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Search of human proteins with 42733592
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42733592 hypothetical protein LOC399693 [Homo sapiens]
(953 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42733592 hypothetical protein LOC399693 [Homo sapiens] 1962 0.0
gi|171184451 centrosome-associated protein 350 [Homo sapiens] 52 3e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 1e-05
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 45 3e-04
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 45 3e-04
gi|33286446 opioid growth factor receptor [Homo sapiens] 45 3e-04
gi|115430243 SCY1-like 1 isoform B [Homo sapiens] 44 6e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 44 6e-04
gi|169209664 PREDICTED: hypothetical protein FLJ39639 [Homo sapi... 43 0.002
gi|113426298 PREDICTED: hypothetical protein FLJ39639 [Homo sapi... 43 0.002
gi|113425870 PREDICTED: hypothetical protein LOC283876 [Homo sap... 43 0.002
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 43 0.002
gi|19924099 synapsin I isoform Ia [Homo sapiens] 42 0.002
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 42 0.003
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ... 42 0.004
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ... 42 0.004
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens] 42 0.004
gi|40353727 synaptopodin isoform A [Homo sapiens] 41 0.005
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 41 0.006
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 40 0.010
gi|19924097 synapsin I isoform Ib [Homo sapiens] 40 0.010
gi|239742514 PREDICTED: similar to Putative POM121-like protein ... 40 0.014
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 40 0.014
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 40 0.014
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 39 0.018
gi|169206171 PREDICTED: hypothetical protein [Homo sapiens] 39 0.018
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 39 0.018
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 39 0.018
gi|163965366 nascent polypeptide-associated complex alpha subuni... 39 0.018
gi|239753377 PREDICTED: hypothetical protein [Homo sapiens] 39 0.023
>gi|42733592 hypothetical protein LOC399693 [Homo sapiens]
Length = 953
Score = 1962 bits (5083), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MPTLVVGTPPTCLGDTPQPCHKNSQRQGPFSHGAPGRAADWKAVAKPRLCAPAAEDDVAA 60
MPTLVVGTPPTCLGDTPQPCHKNSQRQGPFSHGAPGRAADWKAVAKPRLCAPAAEDDVAA
Sbjct: 1 MPTLVVGTPPTCLGDTPQPCHKNSQRQGPFSHGAPGRAADWKAVAKPRLCAPAAEDDVAA 60
Query: 61 LRWPGPSQQPDPPWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDGDSSVSSGRLSC 120
LRWPGPSQQPDPPWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDGDSSVSSGRLSC
Sbjct: 61 LRWPGPSQQPDPPWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDGDSSVSSGRLSC 120
Query: 121 SSGGHDVCVSWKERPPQVLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSA 180
SSGGHDVCVSWKERPPQVLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSA
Sbjct: 121 SSGGHDVCVSWKERPPQVLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSA 180
Query: 181 SRLHKASTLTLRRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQV 240
SRLHKASTLTLRRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQV
Sbjct: 181 SRLHKASTLTLRRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQV 240
Query: 241 PVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGP 300
PVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGP
Sbjct: 241 PVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGP 300
Query: 301 PPVLRRHHSKDPSRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVSGNTPSLA 360
PPVLRRHHSKDPSRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVSGNTPSLA
Sbjct: 301 PPVLRRHHSKDPSRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVSGNTPSLA 360
Query: 361 SFDQPATIQTAMAILQDLRQQIQAGLELAQARKGGQELGPSKRRLQDVAGRGRCRDPNAQ 420
SFDQPATIQTAMAILQDLRQQIQAGLELAQARKGGQELGPSKRRLQDVAGRGRCRDPNAQ
Sbjct: 361 SFDQPATIQTAMAILQDLRQQIQAGLELAQARKGGQELGPSKRRLQDVAGRGRCRDPNAQ 420
Query: 421 SSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPH 480
SSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPH
Sbjct: 421 SSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPH 480
Query: 481 ERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPC 540
ERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPC
Sbjct: 481 ERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPC 540
Query: 541 PRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHA 600
PRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHA
Sbjct: 541 PRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHA 600
Query: 601 LPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKAS 660
LPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKAS
Sbjct: 601 LPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKAS 660
Query: 661 ALRTRELRSRRLQEVYRQQREAVLGRAVPVVSRTTPGIVTFVPSSAQSGGLEASGSLESP 720
ALRTRELRSRRLQEVYRQQREAVLGRAVPVVSRTTPGIVTFVPSSAQSGGLEASGSLESP
Sbjct: 661 ALRTRELRSRRLQEVYRQQREAVLGRAVPVVSRTTPGIVTFVPSSAQSGGLEASGSLESP 720
Query: 721 VLEWSKVTSGMVLGGQEAPGSFCLCLNRAWNHAETLDPPGMGGPQDGRDAPVLLSASPSL 780
VLEWSKVTSGMVLGGQEAPGSFCLCLNRAWNHAETLDPPGMGGPQDGRDAPVLLSASPSL
Sbjct: 721 VLEWSKVTSGMVLGGQEAPGSFCLCLNRAWNHAETLDPPGMGGPQDGRDAPVLLSASPSL 780
Query: 781 GSLELQDLTTRYLPRGMCIYLDPKEAEHLGTSSSLHLRHKQAQLQALETTAKVLKQRVDS 840
GSLELQDLTTRYLPRGMCIYLDPKEAEHLGTSSSLHLRHKQAQLQALETTAKVLKQRVDS
Sbjct: 781 GSLELQDLTTRYLPRGMCIYLDPKEAEHLGTSSSLHLRHKQAQLQALETTAKVLKQRVDS 840
Query: 841 LTAKLQGAEAPDTVRDPAVGLLRSCPHSLPAAPTLATPTLATPACPGALGPNWGRGAPGE 900
LTAKLQGAEAPDTVRDPAVGLLRSCPHSLPAAPTLATPTLATPACPGALGPNWGRGAPGE
Sbjct: 841 LTAKLQGAEAPDTVRDPAVGLLRSCPHSLPAAPTLATPTLATPACPGALGPNWGRGAPGE 900
Query: 901 WVSMQPQPLLPPTYFLEGETLSWGPSWEQQQSVSPRAHCESKPRGVSQAPLLL 953
WVSMQPQPLLPPTYFLEGETLSWGPSWEQQQSVSPRAHCESKPRGVSQAPLLL
Sbjct: 901 WVSMQPQPLLPPTYFLEGETLSWGPSWEQQQSVSPRAHCESKPRGVSQAPLLL 953
>gi|171184451 centrosome-associated protein 350 [Homo sapiens]
Length = 3117
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/190 (26%), Positives = 75/190 (39%), Gaps = 31/190 (16%)
Query: 146 RKSDARLEQLRDKIRAQAWQQ-----GSCASLG-TSAPSSASRLHKASTLTLRRKGQEAK 199
R+ D +LE+L+++IR Q W+ G LG P + + T +R+
Sbjct: 276 RQHDVKLEKLKERIRKQ-WEHSEETNGRGQKLGHIDHPVMVVNVDNSVTAKVRK----VA 330
Query: 200 NPPPAPECSGFSILSAAERRVEAKA-----SHGQGRELSR---------VSQHQVPVLRE 245
PPAP GF+ R + K REL R +S + P +
Sbjct: 331 TAPPAPAYKGFNPSETKIRTPDGKVWQEAEFQNMSRELYRDLALHFADDISIKEKPAEKS 390
Query: 246 KPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGPPPVLR 305
K K+V K +K +L S H L+ +WR GQ LV+ +LGP P +
Sbjct: 391 KEKKVVKPVRKVQKVAQLSSTECRTGSSH------LISTSSWRDGQKLVKKILGPAPRME 444
Query: 306 RHHSKDPSRD 315
+ S D
Sbjct: 445 PKEQRTASSD 454
Score = 40.4 bits (93), Expect = 0.008
Identities = 16/49 (32%), Positives = 35/49 (71%)
Query: 634 HSSESLREFMRQKAQARRRQALEEKASALRTRELRSRRLQEVYRQQREA 682
+ ++ +R+++ ++ + R+R+ EEK + E +++RLQE+YR+Q+EA
Sbjct: 591 YDTDEVRQYIVRQQEERKRKQNEEKKAQKEATEQKNKRLQELYRKQKEA 639
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 49.7 bits (117), Expect = 1e-05
Identities = 113/535 (21%), Positives = 179/535 (33%), Gaps = 84/535 (15%)
Query: 187 STLTLRRKGQEAKNPPPAP--------ECSGFSILSAAERRVEAKASHGQGRELSRVSQH 238
S+ +R+ +EAK P P P E S + +++ + K G+ E S +
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208
Query: 239 QVPVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLL 298
+ ++K R +S S KR+ P +R +KDK +
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT---------------- 252
Query: 299 GPPPVLRRHHSKDPSRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVSGNTPS 358
P P RR H + S D A + D S AA + A + S S ++ G+ P
Sbjct: 253 -PAPKSRRAH-RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAP- 309
Query: 359 LASFDQPATIQTAMAILQDLRQQIQAG----LELAQARKGGQELGPSKRRLQD------- 407
F +P T T + + + + + K PS R
Sbjct: 310 ---FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366
Query: 408 ----VAGRGRCRDPNAQSSFSKSPWAMTERKHSSLERARS-VHTWEPWSSSTARESCPQR 462
G P A + S+ P + +S R RS + E S++ ES P
Sbjct: 367 TPLLAERHGGSPQPLATTPLSQEP--VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPS 424
Query: 463 AWGAQGQDRSFQRPESPHERLGHFSQRPWSAL--------------AGQACSPQRAWGAQ 508
+ + PESP S R S+ + +P R G
Sbjct: 425 PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRS 484
Query: 509 RQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPP 568
R +++R S RS P + + + P RR+ +A P+ R P P
Sbjct: 485 RSPATAKRGRS----RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540
Query: 569 AQRPWSSS------GVQRAGPQGKG-------RGIGSPVSAAKHALPRPTGSFPQNPLGK 615
WS S G R+ +G+ RG + A+ R + +
Sbjct: 541 G---WSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR 597
Query: 616 EKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKASALRTRELRSR 670
R R+ G S S R R ++ RRR ++ A R+ RSR
Sbjct: 598 TPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS--RSRSPARRSGRSRSR 650
Score = 40.8 bits (94), Expect = 0.006
Identities = 70/303 (23%), Positives = 106/303 (34%), Gaps = 33/303 (10%)
Query: 402 KRRLQDVAGRGRCRDPNAQSSFSKSPWAMTERKH--SSLERARSVHTWEPWSSSTARESC 459
K R + + +D + S S +P + R H +S + A S T S S A ++
Sbjct: 228 KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTH 287
Query: 460 PQRAWGAQGQDRSFQRPE--SPHERLGHFS-QRPWS--ALAGQACSPQRAWGAQRQGPSS 514
G S +R E +P G S QRP S Q SP ++ S+
Sbjct: 288 TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA 347
Query: 515 QRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPL--ERPSPPAQR- 571
RP PE+ S P+ P P P A P P PL E +PP++
Sbjct: 348 TRPSPSPERSSTGPEPP------APTP---LLAERHGGSPQPLATTPLSQEPVNPPSEAS 398
Query: 572 -------PWSSSGVQRAGPQGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKD-----T 619
P S + ++ P ++HA P P G ++ T
Sbjct: 399 PTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT 458
Query: 620 LRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKASALRTRELRSRRLQEVYRQQ 679
+ R SHS R R ++ A ++ + + RSR Q +R+
Sbjct: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ--WRRS 516
Query: 680 REA 682
R A
Sbjct: 517 RSA 519
Score = 40.4 bits (93), Expect = 0.008
Identities = 71/298 (23%), Positives = 110/298 (36%), Gaps = 44/298 (14%)
Query: 415 RDPNAQSSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQ 474
R P Q S S S + + K S+ + RS P S + R QR+ + +
Sbjct: 1530 RTPLGQRSRSGSSQEL-DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK 1588
Query: 475 RPESPHERLGHFS----QRPWSA---LAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPF 527
SP S +P +A +G SP+ A R P R GS + R P
Sbjct: 1589 SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
Query: 528 PQQPWSAVATQPCPRRAWTACE-TWEDPGPRLRNPLERPSPPAQRPWSSSG--VQRAGPQ 584
P+ S ++ P ++ TA + P P+ ++ +PP +R SS ++A
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS----RTPPRRRSSRSSPELTRKARLS 1704
Query: 585 GKGRGIGSPVSAAKHALPR----PTGSFPQNPLGKEKDTLR------------------P 622
+ R S PR P+ S P+ P K + + R P
Sbjct: 1705 RRSRSASSSPETRSRTPPRHRRSPSVSSPE-PAEKSRSSRRRRSASSPRTKTTSRRGRSP 1763
Query: 623 CPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKASALRTRELRSRRLQEVYRQQR 680
P+ RGL S R+K + RR+ + + R RSR V R++R
Sbjct: 1764 SPKPRGL------QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRR 1815
Score = 38.5 bits (88), Expect = 0.030
Identities = 64/270 (23%), Positives = 99/270 (36%), Gaps = 20/270 (7%)
Query: 399 GPSKRRLQDVAGRGRCRDPNAQSSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARES 458
G S+ R GR R R P + S S++P R + R RS S R
Sbjct: 571 GRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSP 630
Query: 459 CPQRAWGAQGQDRSFQ-RPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRP 517
+R+ RS + R +P R S+ P ++ +P R G R S+ P
Sbjct: 631 VRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSR----SRTP 686
Query: 518 GSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPG----PRLRNPLERPSPPAQRPW 573
RS P++ S ++ RR + T + G R R S R
Sbjct: 687 ARRGRSRSRTPRRGRS--RSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744
Query: 574 SSSGVQRAG-PQGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRP--------CP 624
SS ++++ + R + SP S AK L +P K+K P P
Sbjct: 745 SSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP 804
Query: 625 RSRGLLGPSHSSESLREFMRQKAQARRRQA 654
+++ P S S +QK++ RQ+
Sbjct: 805 KAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
Score = 38.1 bits (87), Expect = 0.039
Identities = 72/355 (20%), Positives = 118/355 (33%), Gaps = 35/355 (9%)
Query: 261 PKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGPPPVLRRHHSKDPSRDPALTV 320
P PS R ++ S R GQA +SLL P ++D R P +
Sbjct: 2411 PSAPSQSRMTSERAPSPSS--------RMGQAPSQSLLPP--------AQDQPRSPVPSA 2454
Query: 321 DLGDSEKVIAAKCSPVC-AQLPDATSAHSDQQVSGNTPSLASFDQPATIQTAM----AIL 375
D + + A+ +PV +Q + + + +G+ + S P + + A
Sbjct: 2455 -FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 376 QDLRQQIQAGLELAQARKGGQELGPSKRRLQDVAGRGRCRDPNAQSSFSKSPWAMTERKH 435
+ A L+ A+ R+ S + + SS ++ +
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 436 SSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALA 495
+L+R S P RE P A+ + RS S S S+ +
Sbjct: 2574 VALKRVPSP---TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 496 GQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPG 555
+ S + + SS P P + P P P + R ++ D
Sbjct: 2631 SSSSSSSSS-SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
Query: 556 PRLRNPLER------PSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHALPRP 604
+P+ER PSP Q+ SS R G +G R SP + P P
Sbjct: 2690 SLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR---SPSHKRRRETPSP 2741
Score = 34.7 bits (78), Expect = 0.44
Identities = 73/318 (22%), Positives = 124/318 (38%), Gaps = 49/318 (15%)
Query: 389 AQARKGGQELGPSKRRLQDVAGRGRCRDPNAQSSFSKSPWAMTERKHSSLERARSVHTWE 448
+++R + G S+ R GR R R P S S+S R HS + R
Sbjct: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRS-LVRRGRSHSRTPQRRGRS--- 724
Query: 449 PWSSSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQA---CSPQRAW 505
SS+ R++ ++ +Q + RS PE R+ R S+ +A S +R+
Sbjct: 725 --GSSSERKN---KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL 779
Query: 506 GAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERP 565
P Q+ +PP + QP + T PRR+ ++ P P+ ++
Sbjct: 780 SGSSPCP-KQKSQTPPRRSRSGSSQPKAKSRTP--PRRSRSS----SSPPPK-----QKS 827
Query: 566 SPPAQRPWSSSGVQ---RAGPQGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRP 622
P+++ SSS ++G + I SP + + P+ F +P P
Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP--------DP 879
Query: 623 CPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKASALRTRELRSRRLQEVYRQQREA 682
+SR PS S S R K+ RQ+ +S +++ + ++ +
Sbjct: 880 ELKSR---TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP-------QPKVKAIISPRQRS 929
Query: 683 VLGRAVP----VVSRTTP 696
G + P V SRTTP
Sbjct: 930 HSGSSSPSPSRVTSRTTP 947
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 45.1 bits (105), Expect = 3e-04
Identities = 43/130 (33%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 514 SQRPGSPPEKRSPFPQQPWSAVATQPCPRR-AWTACETWEDPGPRLRNPLERPSPPAQRP 572
S+ PG P + SP QP P P++ E P PR P RP+PP QRP
Sbjct: 1112 SRTPGPPSAQSSPIDAQP-----ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP-QRP 1165
Query: 573 WSSSGVQRAGPQGKG-RGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTL---RPCPRSRG 628
SG + P K GIG+P S + R P++P KD + +P P++ G
Sbjct: 1166 PPPSGARSPAPTRKEFGGIGAPPSP---GVARREMEAPKSPGTTRKDNIGRSQPSPQA-G 1221
Query: 629 LLGPSHSSES 638
L GP + S
Sbjct: 1222 LAGPGPAGYS 1231
Score = 32.7 bits (73), Expect = 1.7
Identities = 40/156 (25%), Positives = 62/156 (39%), Gaps = 6/156 (3%)
Query: 512 PSSQRPGSPPEKRSPFPQQPWSAVATQPCP-RRAWTACETWEDPGPRLRNPLERPSPPAQ 570
P RP +PP + +P + P + A P P R+ + PG R +E P P
Sbjct: 1147 PPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGV-ARREMEAPKSPGT 1205
Query: 571 RPWSSSGVQRAGPQGKGRGIG-SPVSAAKHALPRPTG--SFPQNPLGKEKDTLRPCPRSR 627
+ G + PQ G G + S A+ +P G S PQ+ L P +S+
Sbjct: 1206 TRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSK 1265
Query: 628 GLLGPSHSSESLREFMRQKAQARRRQALEEKASALR 663
S S L E ++ +A + +L A L+
Sbjct: 1266 -TSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ 1300
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 45.1 bits (105), Expect = 3e-04
Identities = 43/130 (33%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 514 SQRPGSPPEKRSPFPQQPWSAVATQPCPRR-AWTACETWEDPGPRLRNPLERPSPPAQRP 572
S+ PG P + SP QP P P++ E P PR P RP+PP QRP
Sbjct: 1112 SRTPGPPSAQSSPIDAQP-----ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP-QRP 1165
Query: 573 WSSSGVQRAGPQGKG-RGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTL---RPCPRSRG 628
SG + P K GIG+P S + R P++P KD + +P P++ G
Sbjct: 1166 PPPSGARSPAPTRKEFGGIGAPPSP---GVARREMEAPKSPGTTRKDNIGRSQPSPQA-G 1221
Query: 629 LLGPSHSSES 638
L GP + S
Sbjct: 1222 LAGPGPAGYS 1231
Score = 32.7 bits (73), Expect = 1.7
Identities = 40/156 (25%), Positives = 62/156 (39%), Gaps = 6/156 (3%)
Query: 512 PSSQRPGSPPEKRSPFPQQPWSAVATQPCP-RRAWTACETWEDPGPRLRNPLERPSPPAQ 570
P RP +PP + +P + P + A P P R+ + PG R +E P P
Sbjct: 1147 PPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGV-ARREMEAPKSPGT 1205
Query: 571 RPWSSSGVQRAGPQGKGRGIG-SPVSAAKHALPRPTG--SFPQNPLGKEKDTLRPCPRSR 627
+ G + PQ G G + S A+ +P G S PQ+ L P +S+
Sbjct: 1206 TRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSK 1265
Query: 628 GLLGPSHSSESLREFMRQKAQARRRQALEEKASALR 663
S S L E ++ +A + +L A L+
Sbjct: 1266 -TSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ 1300
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 45.1 bits (105), Expect = 3e-04
Identities = 44/158 (27%), Positives = 58/158 (36%), Gaps = 32/158 (20%)
Query: 509 RQGPSSQRPGSPPEKRSPFP-----QQPWSAVATQPCPRRAWTACE-----TWEDPGPR- 557
R GP PGSP E P P +P + + P PR A A + E PGPR
Sbjct: 507 RTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRP 566
Query: 558 --------LRNPLERPSP---------PAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHA 600
+P E P P PA+ P + G + AGP G S ++
Sbjct: 567 AGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGD----EPAESPSETP 622
Query: 601 LPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSES 638
PRP G P +T P P P+ + E+
Sbjct: 623 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA 660
>gi|115430243 SCY1-like 1 isoform B [Homo sapiens]
Length = 791
Score = 44.3 bits (103), Expect = 6e-04
Identities = 51/236 (21%), Positives = 86/236 (36%), Gaps = 37/236 (15%)
Query: 428 WAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFS 487
WA+T + + RS T P ++ + P+ W Q +D+ S +R +
Sbjct: 572 WAVTGVSSLTSKLIRSHPTTAPTETNIPQRPTPEGHWETQEEDKDTAEDSSTADR---WD 628
Query: 488 QRPWSALAGQACS---PQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRA 544
W +L +A S Q W Q + + + K S P+ WS+ + +
Sbjct: 629 DEDWGSLEQEAESVLAQQDDWSTGGQVSRASQVSNSDHKSSKSPESDWSSWEAE----GS 684
Query: 545 WTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIG-SPVSAAKHALPR 603
W + W++P + PP +S GP+ +G + +SA PR
Sbjct: 685 WE--QGWQEPSSQ--------EPPPDGTRLASEYNWGGPESSDKGDPFATLSARPSTQPR 734
Query: 604 PTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRRQALEEKA 659
P N G E D S + E R+K + RRR+ ++A
Sbjct: 735 PDSWGEDNWEGLETD----------------SRQVKAELARKKREERRREMEAKRA 774
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 44.3 bits (103), Expect = 6e-04
Identities = 73/294 (24%), Positives = 102/294 (34%), Gaps = 48/294 (16%)
Query: 401 SKRRLQDVAGRGRCRDPNAQSS---FSKSPWAMTERKHSSLERARSVHTWEPWSSSTARE 457
S R RG R PNA S + P A +K ++ R E S+ ARE
Sbjct: 378 SVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKEREN---EKEKSALARE 434
Query: 458 SCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRP 517
++ P SP RL SA SP+ S RP
Sbjct: 435 RSLKKRQSL---------PASPRARL--------SASTASELSPKSKARPSSPSTSWHRP 477
Query: 518 GSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLE-RPSPPAQRPWSSS 576
SP P P + P PR T P R+R E + SP A P S
Sbjct: 478 ASP----CPSPGPGHTLPPKPPSPRG------TTASPKGRVRRKEEAKESPSAAGPEDKS 527
Query: 577 GVQRAGPQGKGRGIGSPVSAAKHALPRPTGSFPQN-------PLGKEKDTLRPCPR---- 625
+R K +P S A P PT + PQ P T P P
Sbjct: 528 QSKRRASNEKESA--APASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVT 585
Query: 626 -SRGLLGPSHSSESLREFMRQKAQARRRQALEEKASALRTRELRSRRLQEVYRQ 678
S+ + G + E+ R ++ QAR ++ EE+ L+ + R +++ R+
Sbjct: 586 PSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLARE 639
Score = 42.0 bits (97), Expect = 0.003
Identities = 50/186 (26%), Positives = 70/186 (37%), Gaps = 20/186 (10%)
Query: 518 GSPPE---KRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRN-------PLERPSP 567
G+PP + P P+ + P P + +T D P ++N PLE SP
Sbjct: 12 GAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESP 71
Query: 568 PAQRPWSSSGVQRAGP--QGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRPCPR 625
Q + Q P + K RG P + A P P S +P P +
Sbjct: 72 SGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARP-PRRSSQPSPTAVPASDSPPTKQ 130
Query: 626 SRGLLGPSHSSESLREFMRQKAQARRRQAL---EEKASALRTRELRSRRL----QEVYRQ 678
G H R R K A ++ EEKA ALR ++L+ RR Q + +
Sbjct: 131 EVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAE 190
Query: 679 QREAVL 684
QR A L
Sbjct: 191 QRRAAL 196
>gi|169209664 PREDICTED: hypothetical protein FLJ39639 [Homo
sapiens]
Length = 284
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 501 PQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRN 560
P+ A G +G S +R G P P QP P P ET PG +R
Sbjct: 97 PRAATGTTVRGASVKRTGGPA------PAQPSPPGPLPPTPHGPHARAETGASPGSPVRQ 150
Query: 561 PLERPSPPAQRPWSSSGVQRA 581
PL P+P + W V+RA
Sbjct: 151 PLPGPAPQREAAWGRRRVERA 171
>gi|113426298 PREDICTED: hypothetical protein FLJ39639 [Homo
sapiens]
Length = 284
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 501 PQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRN 560
P+ A G +G S +R G P P QP P P ET PG +R
Sbjct: 97 PRAATGTTVRGASVKRTGGPA------PAQPSPPGPLPPTPHGPHARAETGASPGSPVRQ 150
Query: 561 PLERPSPPAQRPWSSSGVQRA 581
PL P+P + W V+RA
Sbjct: 151 PLPGPAPQREAAWGRRRVERA 171
>gi|113425870 PREDICTED: hypothetical protein LOC283876 [Homo
sapiens]
Length = 284
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 501 PQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRN 560
P+ A G +G S +R G P P QP P P ET PG +R
Sbjct: 97 PRAATGTTVRGASVKRTGGPA------PAQPSPPGPLPPTPHGPHARAETGASPGSPVRQ 150
Query: 561 PLERPSPPAQRPWSSSGVQRA 581
PL P+P + W V+RA
Sbjct: 151 PLPGPAPQREAAWGRRRVERA 171
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 42.7 bits (99), Expect = 0.002
Identities = 58/221 (26%), Positives = 81/221 (36%), Gaps = 26/221 (11%)
Query: 507 AQRQGPSSQRPGSPPEKRSPFPQQ-PWSAVATQPCPRRAWTACETWEDPGPRLRNP-LER 564
A R P++ +PP +P P P +A A PR A A PGP P +R
Sbjct: 114 APRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQR 173
Query: 565 PSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRPCP 624
+P A P + + P R P AA+ P P P ++ +P P
Sbjct: 174 AAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP 233
Query: 625 RSRG---LLGPSHSSESLREFMR----------QKAQARRRQALEEKASALRTRELRSRR 671
G G + SLRE +R + + R + LEE+A+A E
Sbjct: 234 PPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLG 293
Query: 672 LQEVYRQQREAVLGRAVPVVSRTTPGIVTFVPSSAQSGGLE 712
+ R R GRA P S PS ++ GG E
Sbjct: 294 ALALPRGDRP---GRAPPAASAR--------PSRSKRGGEE 323
Score = 32.3 bits (72), Expect = 2.2
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 843 AKLQGAEAPDTVRDPAVGLLRSCPHSLPAAPTLATPTLATPACPGALGPNWG-RGAPGEW 901
A+ A A P+ G + P + AAP A P PA P A+ P G R AP
Sbjct: 146 ARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP--APAAPPAVAPPAGPRRAPPPA 203
Query: 902 VSMQPQPLLPP 912
V+ + PL PP
Sbjct: 204 VAAREPPLPPP 214
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/196 (27%), Positives = 68/196 (34%), Gaps = 46/196 (23%)
Query: 495 AGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDP 554
A QA P + G Q + P + PG+PP R P P P+R P
Sbjct: 519 ASQAAPPTQGQGRQSR-PVAGGPGAPPAARPP----------ASPSPQRQAGP------P 561
Query: 555 GPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHA------------LP 602
+ + P+PP G QR GP K G P A A P
Sbjct: 562 QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQP 621
Query: 603 RPTGSFPQNPLGKEKDTLR-------PCPRSRGLLGPSH----SSESLREFMRQKAQARR 651
RP+G P G+ K L P P + GP H S+SL A
Sbjct: 622 RPSG---PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPP 678
Query: 652 RQAL---EEKASALRT 664
R +L E KA +R+
Sbjct: 679 RPSLSQDEVKAETIRS 694
Score = 38.5 bits (88), Expect = 0.030
Identities = 50/167 (29%), Positives = 65/167 (38%), Gaps = 29/167 (17%)
Query: 487 SQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKR-SPFPQQPWSAV---ATQPCPR 542
SQ+P A Q PQ G + GP QR G P ++R P QQ S + A P P+
Sbjct: 449 SQQPAGPPAQQRPPPQG--GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQ 506
Query: 543 RAWTACETWEDPGPRLRNPLE------RP------SPPAQRPWSSSGVQR-AGPQGKGRG 589
R + + P + P + RP +PPA RP +S QR AGP R
Sbjct: 507 RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566
Query: 590 IGSPVSAAKHALPRPTGSF-----PQNPLG-----KEKDTLRPCPRS 626
A A P G PQ P G ++ P PR+
Sbjct: 567 TSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613
Score = 33.5 bits (75), Expect = 0.97
Identities = 50/151 (33%), Positives = 57/151 (37%), Gaps = 51/151 (33%)
Query: 466 AQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQG-PSSQRPGSPPEKR 524
AQ R QR SP R H GQ SP GA G +SQ+P PP ++
Sbjct: 415 AQALPRQRQRDASPG-RGSH----------GQTPSP----GALPLGRQTSQQPAGPPAQQ 459
Query: 525 SPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQ 584
P PQ P P PGP +R PP Q QR PQ
Sbjct: 460 RPPPQ------GGPPQP-----------GPGP------QRQGPPLQ--------QRPPPQ 488
Query: 585 GKGR--GIGSPV-SAAKHALPRPTGSFPQNP 612
G+ G+G P S LP PT S PQ P
Sbjct: 489 GQQHLSGLGPPAGSPLPQRLPSPT-SAPQQP 518
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 42.0 bits (97), Expect = 0.003
Identities = 108/529 (20%), Positives = 169/529 (31%), Gaps = 61/529 (11%)
Query: 141 PQQRPRKSDARLEQLRDKIRAQAWQQGSCA-SLGTSAPSSASRLHKASTLTLRRKGQEAK 199
P R R S R E+ R R+ + S + S L + S QEA
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEAT 239
Query: 200 N-----------PPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQVPVLREKPK 248
+ P P P+ S E+ E + R SR +P+
Sbjct: 240 STSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPR 299
Query: 249 RVKSSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVR-------SLLGPP 301
R S + + PSPRR + + + R+ ++ VR SL G
Sbjct: 300 RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSS 359
Query: 302 PVLRRHHSKDP--------SRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVS 353
S+ P S P T L S + P P + HS
Sbjct: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419
Query: 354 GNTPSLASFDQPATIQTAMAILQDLRQQIQAGLELAQARK-----GGQELGPSKRRLQDV 408
N + + ++ ++ + RK ++ G V
Sbjct: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV 479
Query: 409 AGRGRCRDPNAQSSFSKSPWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQG 468
R + R N QSS + +E + ++ S +R + P
Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS------- 532
Query: 469 QDRSFQRPESPHERLGHFSQRPWSAL--AGQACSPQRAWGAQRQGPSSQRPGSPPEKRSP 526
R Q+ SP R P + + P R P + P PP +RSP
Sbjct: 533 -PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSP 591
Query: 527 FPQQPWSAV----ATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGV--QR 580
P++ + + P P+R T P P R PSPP +R S S QR
Sbjct: 592 SPRRYSPPIQRRYSPSPPPKR-----RTASPPPPPKRRA--SPSPPPKRRVSHSPPPKQR 644
Query: 581 AGPQGKGRGIGSPVSAAKH---ALPRPTGSFPQNPLGKEKDTLRPCPRS 626
+ P K R SP ++KH + P + ++P ++ + P PR+
Sbjct: 645 SSPVTKRR---SPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Score = 38.1 bits (87), Expect = 0.039
Identities = 103/465 (22%), Positives = 163/465 (35%), Gaps = 95/465 (20%)
Query: 132 KERPPQVLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSASRLHKASTLTL 191
+ PP+ + P R R+S + + + R + S + G+S+ SS+SR
Sbjct: 325 RRTPPRRMPPPPRHRRSRSPVRRRR---------RSSASLSGSSSSSSSSR--------- 366
Query: 192 RRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQVPVLREKPKRVK 251
+++PP P S RR+ AS + R P R P +
Sbjct: 367 ------SRSPPKKPP-KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419
Query: 252 SSSCKREKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKGQALVRSLLGPPPVLRRHHSKD 311
S+ ++ + P KHK + R P P R+
Sbjct: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEK---------------RESPSPAPKPRK----- 459
Query: 312 PSRDPALTVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVSGNTPSLASFDQPATIQTA 371
V+L +SE+ K + + +QQ S ++ S +S +
Sbjct: 460 --------VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE------ 505
Query: 372 MAILQDLRQQIQAGLELAQARKGG--QELGPSKRRLQ-DVAGRGRCR----DPNAQSSFS 424
+ R ++ G E+ + R+ + PS R+ Q + + RGR R P + S
Sbjct: 506 ----RPKRSHVKNG-EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
Query: 425 KSPWAMTERKHSSLERARSVHTWEP---WSSSTARESCP-QRAWG-AQGQDRSFQRPESP 479
SP R+ + R P S S R S P QR + + R P P
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620
Query: 480 HERLGHFSQRPWSALAGQACSPQRAWGA-QRQGPS---SQRPGSPPEKRSPFPQQPWSAV 535
+R S P ++ QR+ +R+ PS R GS P + + + P
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP---- 676
Query: 536 ATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQR 580
QP R + P PR R P SPP R +SS QR
Sbjct: 677 --QPNKRHS---------PSPRPRAPQTSSSPPPVRRGASSSPQR 710
Score = 33.1 bits (74), Expect = 1.3
Identities = 59/272 (21%), Positives = 89/272 (32%), Gaps = 30/272 (11%)
Query: 400 PSKRRLQDVAGRGRCRDPNAQSSFSK--SPWAMTERKHSSLERARSVHTWEPWSSSTARE 457
P K+R V R R P+ S K SP T S R + P + T+
Sbjct: 640 PPKQRSSPVTKR---RSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSS 696
Query: 458 SCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRP 517
P R GA + Q P + S+ P +A SP + R+ SS+
Sbjct: 697 PPPVRR-GASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ--SVRRVSSSRSV 753
Query: 518 GSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSG 577
PE + P P P P ++ + W P + PSP R G
Sbjct: 754 SGSPEPAAKKPPAP-------PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806
Query: 578 --------------VQRAGPQGKGRGIGSPVSAAKHALPRPTG-SFPQNPLGKEKDTLRP 622
+ + K V+AA A P + L +E+ P
Sbjct: 807 GGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAP 866
Query: 623 CPRSRGLLGPSHSSESLREFMRQKAQARRRQA 654
P+ + + L + +R+KA R+A
Sbjct: 867 EPKKETESEAEDNLDDLEKHLREKALRSMRKA 898
Score = 32.3 bits (72), Expect = 2.2
Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 13/174 (7%)
Query: 105 EARDGDSSVSSGRLSCSSGGHDVCVSWKERPPQVLGPQQRPRK-SDARLEQLRDKIRAQA 163
E ++ DS + L+ G + E P +L Q+ A LE +++I+ +
Sbjct: 76 EVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQ 135
Query: 164 WQQGSCASLGTSAPSSASRLHKASTLTLRRKGQEAKNPPPAPECSGFSILSAAERRVEAK 223
+Q AS+ R K + R K + +++P S ++ R E K
Sbjct: 136 IEQEKLASMKKQDEDKDKR-DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERK 194
Query: 224 ASHGQGRELSRVSQHQVPVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDE 277
SH SR +H R K + + K+EKTP+LP P K+ E
Sbjct: 195 RSH------SRSPRH-----RTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
sapiens]
Length = 384
Score = 41.6 bits (96), Expect = 0.004
Identities = 44/150 (29%), Positives = 58/150 (38%), Gaps = 10/150 (6%)
Query: 452 SSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQG 511
S T + P R +Q Q S RP +P R G S R A A + + A G G
Sbjct: 99 SGTTFSAVPPRP--SQHQSGSRLRPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASG 156
Query: 512 PSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQ- 570
S PGS + +P S QP P C R P RP P +
Sbjct: 157 GSG--PGSRGQGSDQVGARP-SRAGGQPPP----LTCRRCRAAPRRSARPFRRPGLPLKS 209
Query: 571 RPWSSSGVQRAGPQGKGRGIGSPVSAAKHA 600
RP S +G + G G G G G+ +++ A
Sbjct: 210 RPGSGTGARSCGTWGSGGGPGTAAASSPSA 239
>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
sapiens]
Length = 384
Score = 41.6 bits (96), Expect = 0.004
Identities = 44/150 (29%), Positives = 58/150 (38%), Gaps = 10/150 (6%)
Query: 452 SSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQG 511
S T + P R +Q Q S RP +P R G S R A A + + A G G
Sbjct: 99 SGTTFSAVPPRP--SQHQSGSRLRPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASG 156
Query: 512 PSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQ- 570
S PGS + +P S QP P C R P RP P +
Sbjct: 157 GSG--PGSRGQGSDQVGARP-SRAGGQPPP----LTCRRCRAAPRRSARPFRRPGLPLKS 209
Query: 571 RPWSSSGVQRAGPQGKGRGIGSPVSAAKHA 600
RP S +G + G G G G G+ +++ A
Sbjct: 210 RPGSGTGARSCGTWGSGGGPGTAAASSPSA 239
>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
Length = 384
Score = 41.6 bits (96), Expect = 0.004
Identities = 44/150 (29%), Positives = 58/150 (38%), Gaps = 10/150 (6%)
Query: 452 SSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQG 511
S T + P R +Q Q S RP +P R G S R A A + + A G G
Sbjct: 99 SGTTFSAVPPRP--SQHQSGSRLRPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASG 156
Query: 512 PSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQ- 570
S PGS + +P S QP P C R P RP P +
Sbjct: 157 GSG--PGSRGQGSDQVGARP-SRAGGQPPP----LTCRRCRAAPRRSARPFRRPGLPLKS 209
Query: 571 RPWSSSGVQRAGPQGKGRGIGSPVSAAKHA 600
RP S +G + G G G G G+ +++ A
Sbjct: 210 RPGSGTGARSCGTWGSGGGPGTAAASSPSA 239
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 41.2 bits (95), Expect = 0.005
Identities = 100/449 (22%), Positives = 145/449 (32%), Gaps = 80/449 (17%)
Query: 130 SWKERPPQ--VLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSASRLHKAS 187
SW PP VL P P+ S + Q + G S A R + S
Sbjct: 332 SWVRSPPSYSVLYPSSDPKSSHLK------------GQAVPASKTGILEESMARRGSRKS 379
Query: 188 TLTLRRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGR------------ELSRV 235
T K + NP +L + E + QG E S
Sbjct: 380 MFTFVEKPKVTPNP---------DLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNF 430
Query: 236 SQHQVPVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDED--SELVGVYAWRKGQAL 293
Q P R++ + E L SPR AK K K SE G KG L
Sbjct: 431 QQEPAP--RDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASG-----KGAEL 483
Query: 294 V---RSLLGPPPVLRRHHSKDPSRDPALTVDLGDSEKVIA--------AKCSPVCAQLPD 342
+S + + H+ + +R P+ T+ L S K A SP A+ P
Sbjct: 484 YARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSP--ARTPP 541
Query: 343 ATSAHSDQQVSGNTPSLASFDQPATIQTAMAILQDLRQQIQAGLELAQ-ARKGGQELGPS 401
A+ H +G + P ++ ++ +L +++ + A A+ +L P+
Sbjct: 542 ASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPN 601
Query: 402 KRR----LQDVAGRGRCRDPNAQSS---FSKSPWAMTERKHSSLERARSVHTWEPWSSST 454
+ R P +S S P A++ + W P +
Sbjct: 602 LPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQA 661
Query: 455 ARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAW---GAQRQG 511
R S R G + QDR P SP PW+ A + S W G G
Sbjct: 662 PRPSFSTRNAGIEAQDRRESLPTSP----------PWTPGASRPPSSLDGWVSPGPWEPG 711
Query: 512 PSSQRPGSPPEKRSPFPQQP-WSAVATQP 539
S SPP P P P WS + P
Sbjct: 712 RGSSM-SSPPPLPPPPPMSPSWSERSVSP 739
Score = 33.9 bits (76), Expect = 0.74
Identities = 65/271 (23%), Positives = 86/271 (31%), Gaps = 44/271 (16%)
Query: 15 DTPQPCHKNSQRQGPFSHGAPGRAADWKAVAKPRLCAPAAEDDVAAL--RWPGPSQQPDP 72
D+ QP + G S +P RA +A PR + A R P+ P
Sbjct: 630 DSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWT 689
Query: 73 PWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDGDSSVSSGRLSCSSGGHDVCVSWK 132
P A+ D PGPW M S P S SW
Sbjct: 690 PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMS----------------PSWS 733
Query: 133 ERPPQVLGPQQRPRKSDARLEQL--RDKIRAQAWQQGSCASLGTSAPSSASRLHKASTLT 190
ER L P+ R +L+ L R+ I A + S S G P S
Sbjct: 734 ERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFS--------- 784
Query: 191 LRRKGQEAKNPPPAPECSGFSILSAAERRVEAKASHGQGRELSRVSQHQVPVLREKPKRV 250
A PPP P + S R + A G P+ R P
Sbjct: 785 ----PPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAA---------FAPIPR-SPLPA 830
Query: 251 KSSSCKREKTPKLPSPRRAAKDKHKDEDSEL 281
SSC ++P LP+P R + DS++
Sbjct: 831 GPSSCTSPRSP-LPAPPRPFLYRRSPTDSDV 860
Score = 33.9 bits (76), Expect = 0.74
Identities = 54/195 (27%), Positives = 67/195 (34%), Gaps = 34/195 (17%)
Query: 427 PWAM-TERKHSSLERARSVHTWEPW---SSSTARESCPQRAWGAQGQDRSFQ--RPES-- 478
PW R SSL+ S WEP S S+ P +RS RPE+
Sbjct: 687 PWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEA 746
Query: 479 --PHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQR---------PGSPPEKRSPF 527
P +L R A + + R+ GA+ P S P PP RSP
Sbjct: 747 RPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQ 806
Query: 528 PQQPWSA----VATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGP 583
P +P SA A P PR A GP P P RP+ + R P
Sbjct: 807 PARPGSAAVPGAAFAPIPRSPLPA-------GPSSCTSPRSPLPAPPRPF----LYRRSP 855
Query: 584 QGKGRGIGSPVSAAK 598
+ S S AK
Sbjct: 856 TDSDVSLDSEDSGAK 870
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 40.8 bits (94), Expect = 0.006
Identities = 111/465 (23%), Positives = 171/465 (36%), Gaps = 69/465 (14%)
Query: 263 LPSPRRAAKDKHKDEDSELVGVYAWRKGQAL-VRSLLGP-PPVLRRHH-----SKDPSRD 315
L R+ + K +E +GV R G L ++S G PP L S+ P+
Sbjct: 466 LTGKRQDSGTMKKPHTTEEIGVPISRNGSTLGLKSQNGCIPPKLPSGSPSPKLSQTPTHM 525
Query: 316 PALTVDLGDSEKVIAAK--CSPVCAQ-LPDATSAHSDQQVSGNTPSLASFD-----QPAT 367
P + D G K A SP AQ LP ++++S + S S S D P
Sbjct: 526 PTILDDPGKKVKKPAPPQHFSPRTAQGLPGTSNSNSSRSGSQRQGSWDSRDVVLSTSPKL 585
Query: 368 IQTAMAILQDLRQQIQ-AGLELAQARKGGQELGPSKRRLQDVAGRGRCRDPNAQSSFSKS 426
+ TA A L+ + AGL+ R+G P + +A S +K+
Sbjct: 586 LATATANGHGLKGNDESAGLD----RRGSSSSSP---------------EHSASSDSTKA 626
Query: 427 PWAMTERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRP---ESPHERL 483
P T R + A + E S+ P GA + + P + E
Sbjct: 627 P--QTPRSGA----AHLCDSQETNCSTAGHSKTPPS--GADSKTVKLKSPVLSNTTTEPA 678
Query: 484 GHFSQRPWSALAGQACSPQRAWGAQRQG--PSSQRPGS----PPEKRSPFPQQPWS---A 534
S P LA A W A P P S P + P W A
Sbjct: 679 STMSPPPAKKLALSAKKASTLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVASTWPVHRA 738
Query: 535 VATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPV 594
A P P+ + + + P P L + +P P P S S + A PQ + +
Sbjct: 739 RAVSPAPQSS-SRLQPPFSPHPTLLSSTPKP-PGTSEPRSCSSISTALPQ-----VNEDL 791
Query: 595 SAAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGLLG--PSHSSESLREFMRQKAQARRR 652
+ H LP + PQ+P K K T P+ G P H E+ ++ + +++
Sbjct: 792 VSLPHQLPEASEP-PQSPSEKRKKTFVGEPQRLGSETRLPQHIREATAAPHGKRKRKKKK 850
Query: 653 QALEEKASALRTRELRSRRLQEVYRQQREAVLGRAVPVVSRTTPG 697
+ + ASAL+ + + + +YR++ +A L P V R G
Sbjct: 851 RPEDTAASALQEGQTQRQPGSPMYRREGQAQL----PAVRRQEDG 891
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 40.0 bits (92), Expect = 0.010
Identities = 46/154 (29%), Positives = 64/154 (41%), Gaps = 11/154 (7%)
Query: 514 SQRPGSPPEKRSPFPQQPWSAVATQPCPRR-AWTACETWEDPGPRLRNPLERPSPPAQRP 572
S+ PG P + SP QP P P++ E P PR P RP+PP QRP
Sbjct: 1068 SRTPGPPSAQSSPIDAQP-----ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP-QRP 1121
Query: 573 WSSSGVQRAGPQGKGRGIG-SPVSAAKHALPRPTG--SFPQNPLGKEKDTLRPCPRSRGL 629
SG + PQ G G + S A+ +P G S PQ+ L P +S+
Sbjct: 1122 PPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSK-T 1180
Query: 630 LGPSHSSESLREFMRQKAQARRRQALEEKASALR 663
S S L E ++ +A + +L A L+
Sbjct: 1181 SETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ 1214
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 40.0 bits (92), Expect = 0.010
Identities = 43/159 (27%), Positives = 54/159 (33%), Gaps = 39/159 (24%)
Query: 495 AGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDP 554
A QA P + G Q + P + PG+PP R P P P+R P
Sbjct: 519 ASQAAPPTQGQGRQSR-PVAGGPGAPPAARPP----------ASPSPQRQAGP------P 561
Query: 555 GPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHA------------LP 602
+ + P+PP G QR GP K G P A A P
Sbjct: 562 QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQP 621
Query: 603 RPTGSFPQNPLGKEKDTLR-------PCPRSRGLLGPSH 634
RP+G P G+ K L P P + GP H
Sbjct: 622 RPSG---PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPH 657
Score = 38.5 bits (88), Expect = 0.030
Identities = 50/167 (29%), Positives = 65/167 (38%), Gaps = 29/167 (17%)
Query: 487 SQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKR-SPFPQQPWSAV---ATQPCPR 542
SQ+P A Q PQ G + GP QR G P ++R P QQ S + A P P+
Sbjct: 449 SQQPAGPPAQQRPPPQG--GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQ 506
Query: 543 RAWTACETWEDPGPRLRNPLE------RP------SPPAQRPWSSSGVQR-AGPQGKGRG 589
R + + P + P + RP +PPA RP +S QR AGP R
Sbjct: 507 RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566
Query: 590 IGSPVSAAKHALPRPTGSF-----PQNPLG-----KEKDTLRPCPRS 626
A A P G PQ P G ++ P PR+
Sbjct: 567 TSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613
Score = 33.5 bits (75), Expect = 0.97
Identities = 50/151 (33%), Positives = 57/151 (37%), Gaps = 51/151 (33%)
Query: 466 AQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQG-PSSQRPGSPPEKR 524
AQ R QR SP R H GQ SP GA G +SQ+P PP ++
Sbjct: 415 AQALPRQRQRDASPG-RGSH----------GQTPSP----GALPLGRQTSQQPAGPPAQQ 459
Query: 525 SPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQ 584
P PQ P P PGP +R PP Q QR PQ
Sbjct: 460 RPPPQ------GGPPQP-----------GPGP------QRQGPPLQ--------QRPPPQ 488
Query: 585 GKGR--GIGSPV-SAAKHALPRPTGSFPQNP 612
G+ G+G P S LP PT S PQ P
Sbjct: 489 GQQHLSGLGPPAGSPLPQRLPSPT-SAPQQP 518
>gi|239742514 PREDICTED: similar to Putative POM121-like protein
1-like [Homo sapiens]
Length = 896
Score = 39.7 bits (91), Expect = 0.014
Identities = 101/457 (22%), Positives = 160/457 (35%), Gaps = 59/457 (12%)
Query: 89 GPWGKACSLPMWSTGPEARDGDSSVSSGRLSCSSGGHDVCVSWKERPPQVLGPQQRPRKS 148
GP C L S+ + DG +VSSG C P Q L P+ +S
Sbjct: 411 GPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTA-------PGQTLAPRGGSPRS 463
Query: 149 DARLEQLRDKIRAQAWQQGSC---------ASLGTSAPSSASRLHKASTLTLRRKGQEAK 199
A + + + C +SL T A S + KA T+ + +
Sbjct: 464 QASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGA-SRGPPVSKAPTMDAQ------Q 516
Query: 200 NPPPAPECSGF--SILSAAERRVEAKASHGQGRELSRVSQHQVPVLREKPKRVKSSSCKR 257
+ P + +C G + SAAE A S + R + P+ P S
Sbjct: 517 DRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPL----PATSSHSRDSA 572
Query: 258 EKTPKLPSPRRAAKDKHKDEDSELVGVYAWRKG-QALVRSLLGPPPVLRRHHSKDPSRDP 316
+ T +P+P AA S G+ R G A + PPP + +P+
Sbjct: 573 QVTSMIPAPFTAA--------SRDAGMRRTRPGTSAPAAAAAAPPP-----STLNPTSGS 619
Query: 317 AL-TVDLGDSEKVIAAKCSPVCAQLPDATSAHSDQQVSGNTPSLASFDQPATIQTAMAIL 375
L VD G S + +A + A+ + ++ + + T S + ++ ++ L
Sbjct: 620 LLNAVDEGPSHFLASATAA---ARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTEGL 676
Query: 376 QDLRQQ---IQAGLELAQARKGG-QELGPSKRRLQDVAGRGRCRDPNAQSSFSKSPWAMT 431
Q+L+++ + +LA + E GP +D RC + + +P +
Sbjct: 677 QELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDT----RCEKADTAPGQTLAPRGGS 732
Query: 432 ERKHSSLERARSVHTWEPWSSSTARESCPQRAWGAQGQDRSFQRPESPHERLGHFSQRPW 491
R +S R S E + S R S P + S P S + RP
Sbjct: 733 PRSQASRPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPK 792
Query: 492 SALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFP 528
S Q C A A SS P S + R P P
Sbjct: 793 S----QDCLGLVAPLASAAEVSSTAPVSGKKHRPPGP 825
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 39.7 bits (91), Expect = 0.014
Identities = 105/480 (21%), Positives = 168/480 (35%), Gaps = 101/480 (21%)
Query: 18 QPCHKNSQRQGPFSHGAPGRAADWKAVAKPRLCAPAAEDDVAALRWPGPSQ-------QP 70
+P +N Q + G + KAVA E+D + S+ Q
Sbjct: 828 KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 887
Query: 71 DPPWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDG---DSSVSSGRLSCSSGGHDV 127
P + + + P A P TGP A D S SS S S G
Sbjct: 888 KPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 947
Query: 128 CVSWKE--RPPQVLGPQQRPRKSDARLEQLRDKIRAQAWQQGSCASLGTSAPSSASRLHK 185
V+ + +PP + P +S A G A+ + +S R +
Sbjct: 948 AVTSAQVIKPPLIFVD---PNRSPA----------------GPAATPAQAQAASTPRKAR 988
Query: 186 ASTLTLRRKGQEAKNPP--PAPEC------SGFSILSAAERRVEAKASHG---QGRELSR 234
AS T R E+++ PA +C + + A R+ KAS +E SR
Sbjct: 989 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSR 1048
Query: 235 VSQHQ---------------VPVLREKPKRVKSSSCKREKTPKLPSPRRAAKDKHKDEDS 279
+S + +P + V++ + + PKLP ++A K +DS
Sbjct: 1049 ISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDS 1108
Query: 280 ELVGVYA--------WRKGQALVRSLLGPPPVLRRHHSKDPSRDPAL---TVDLGDSEKV 328
E + +G +L+GP PSR L T + V
Sbjct: 1109 EDSSDSSSGSEEDGEGPQGAKSAHTLVGP----------TPSRTETLVEETAAESSEDDV 1158
Query: 329 IAAKCSPVCAQL-PDATSAHSDQQVSGNTPSLASFDQPATIQTAMAI------LQDLRQQ 381
+A S + + P T A+S Q S TP L D ++ + +A Q+ + Q
Sbjct: 1159 VAPSQSLLSGYMTPGLTPANS--QASKATPKL---DSSPSVSSTLAAKDDPDGKQEAKPQ 1213
Query: 382 IQAGLELAQARKGGQELG----PSK-RRLQDVAGRGRCRDPNAQSSFSK----SPWAMTE 432
AG + + GG+E P K R+ + AG + QS+ ++ PW + E
Sbjct: 1214 QAAG--MLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNE 1271
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 39.7 bits (91), Expect = 0.014
Identities = 48/170 (28%), Positives = 67/170 (39%), Gaps = 21/170 (12%)
Query: 481 ERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGS----PPEKRSPFPQQPWSAVA 536
E LG QR + G+ C P +A Q +G SS PGS PP K S P + A
Sbjct: 744 EPLGASVQR--DSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPA-- 799
Query: 537 TQPCPRRAWTACETWEDPGPRL--RNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPV 594
+P P + + GP P P PP S +R G + +G G +P
Sbjct: 800 -EPIPPGVASGGLRPDALGPTTAHHGPRHPPKPP-----RSKATERPGQEPEGPG-ATPA 852
Query: 595 SAAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMR 644
P S P+ P ++ PC + L G + + SL+E R
Sbjct: 853 GERDDQSP---DSVPERPRPADRRLCLPCVDASPLPGRT-ACPSLQEATR 898
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 39.3 bits (90), Expect = 0.018
Identities = 48/176 (27%), Positives = 70/176 (39%), Gaps = 25/176 (14%)
Query: 530 QPWSAVATQPCPRRAWTACET------WEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGP 583
+PW +ATQP R ET E GP L P R P Q P S + G
Sbjct: 745 EPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLSPP--RAIPGDQHPESPVHTEPMGI 802
Query: 584 QGKGRG-----IGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSES 638
QG+GR +G P A+ P + PL +E + L P R + G ++
Sbjct: 803 QGRGRQTVDKVMGIPKETAERVGPE------RGPLERETEKLLP-ERQTDVTGEEELTKG 855
Query: 639 LREFMRQKAQARRRQALE-----EKASALRTRELRSRRLQEVYRQQREAVLGRAVP 689
++ +++ AR Q E E AS R RE ++ Q + V + +P
Sbjct: 856 KQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLP 911
>gi|169206171 PREDICTED: hypothetical protein [Homo sapiens]
Length = 466
Score = 39.3 bits (90), Expect = 0.018
Identities = 58/204 (28%), Positives = 71/204 (34%), Gaps = 36/204 (17%)
Query: 463 AWGAQGQDRSFQRPESPHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPE 522
A GA+ Q R ++ P L P S LAG C RA G G
Sbjct: 225 AAGARAQVRGSEKRACPGSTLP-----PSSVLAG--CVGTRARGH----------GGVQR 267
Query: 523 KRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAG 582
+R P + T P P RA P PR +PPA+ G
Sbjct: 268 QRFSAPSSHSTGARTLPTPSRARPG-----KPAPR------GSAPPARLRGGGGGSGLTQ 316
Query: 583 PQGKGRGIGSPVSAAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHS----SES 638
G GRG G S HAL GS P+G LR P R L P+ S S
Sbjct: 317 LVGSGRGSGVTHSVGTHALATRRGSRAPRPVG----VLRGVPHFRPLSSPAPQSPPRSPS 372
Query: 639 LREFMRQKAQARRRQALEEKASAL 662
+R F + R +A+AL
Sbjct: 373 VRAFGPRLGAGRLSCPQAPRAAAL 396
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 39.3 bits (90), Expect = 0.018
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 520 PPEKRSPFPQQPWSAVATQPCPRRAWTACETWEDPGPRLRNPLERPSP-PAQRPWSSSGV 578
PP + PQQP + + P P+R+ GPR PL RP+P PA+RP S
Sbjct: 310 PPFRAGTPPQQPTAPSSEWPGPQRS-------PGTGPRWTAPLPRPAPLPAKRPGDSPAS 362
Query: 579 QRAGPQG 585
+R P G
Sbjct: 363 KRPRPGG 369
Score = 35.0 bits (79), Expect = 0.33
Identities = 37/135 (27%), Positives = 50/135 (37%), Gaps = 22/135 (16%)
Query: 15 DTPQPCHKNSQRQGPFSHGAPG--RAADWKAVAKPRLCAPAAEDDVAALRWPGPSQQP-- 70
+TP P + Q P SHG P D + R P + + WPGP + P
Sbjct: 281 NTPPPIPGSDQ---PSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEWPGPQRSPGT 337
Query: 71 DPPWAAPHVVGSD-DLKEPGPWGKACSLPMWSTGPEARD---GDSSVSSGRLSCSSGGHD 126
P W AP + K PG + PEARD G++ + S + +G
Sbjct: 338 GPRWTAPLPRPAPLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSEAAGETG--- 394
Query: 127 VCVSWKERPPQVLGP 141
P QV GP
Sbjct: 395 --------PTQVRGP 401
Score = 33.1 bits (74), Expect = 1.3
Identities = 42/145 (28%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 499 CSPQRAWGAQRQ--GPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACET--WEDP 554
C P RA +Q PSS+ PG +RSP W+A +P P A ++ + P
Sbjct: 309 CPPFRAGTPPQQPTAPSSEWPGP---QRSPGTGPRWTAPLPRPAPLPAKRPGDSPASKRP 365
Query: 555 GPRLRNPLERPSPPAQRP-WSSSGVQRAGP--------------QGKGR-----GIGSPV 594
P +P R P + P SS GP QGKGR G G
Sbjct: 366 RPGGVSPEARDPPKGENPLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSP 425
Query: 595 SAAKHALPRPTGSFPQNPLGKEKDT 619
A L +P S P L + +T
Sbjct: 426 RPAPPRLGKPPRSRPPQGLAQPPET 450
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 39.3 bits (90), Expect = 0.018
Identities = 56/214 (26%), Positives = 83/214 (38%), Gaps = 27/214 (12%)
Query: 490 PWSALAGQACSPQ-----RAWGAQRQGPSSQRPGSPP-EKRSPFPQQPWSA--------V 535
P S G A PQ RA +RQ PS + P K SP ++ A
Sbjct: 1213 PSSDRHGPATGPQGVPEVRAGPDRRQHPSLESSYPPDLHKSSPHGEKRAHARDPKGSREY 1272
Query: 536 ATQPCPRRAWTACETWEDPG---PRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGS 592
+ QP W D G P+ R P R A+R +++G +R P+ + G S
Sbjct: 1273 SRQPNEHHTWNGTSRKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSPEKRREGTRS 1332
Query: 593 PVSAAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGLLGPSHSSESLREFMRQKAQARRR 652
A + L R + + E+ R R R PS SL + Q+ RR
Sbjct: 1333 ----ADNTLERREKHEKRRDVSPERRRERSPTRRRDG-SPSRRRRSLERLLEQRRSPERR 1387
Query: 653 Q--ALEEKASALRTRELRS---RRLQEVYRQQRE 681
+ + E +A + R RS RR + + ++ RE
Sbjct: 1388 RGGSPERRAKSTDRRRARSPERRRERSLDKRNRE 1421
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 39.3 bits (90), Expect = 0.018
Identities = 40/127 (31%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 496 GQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTA-CETWEDP 554
G P + + GP++ P P + P P AT P P+ A T T P
Sbjct: 938 GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT-PSPKGAPTPPAATPPSP 996
Query: 555 --GPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAKHALPRPTGSFPQNP 612
GP +P P+PPA P S G A P K G +P +A P P GS P
Sbjct: 997 KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK--GASTPPAATP---PSPKGSPAATP 1051
Query: 613 LGKEKDT 619
L K T
Sbjct: 1052 LPKGAPT 1058
Score = 34.3 bits (77), Expect = 0.57
Identities = 36/132 (27%), Positives = 49/132 (37%), Gaps = 15/132 (11%)
Query: 496 GQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRA-WTACETWEDP 554
G +P + + G ++ P P + P P +AT P P+ A T T P
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTPAATPPSP 1251
Query: 555 --GPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKG----------RGIGSPVSAAKHALP 602
GP P P+PPA P S G A P KG G P ++ P
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 603 RPTGSFPQNPLG 614
P + P +P G
Sbjct: 1311 TPPAATPPSPKG 1322
Score = 32.3 bits (72), Expect = 2.2
Identities = 33/138 (23%), Positives = 47/138 (34%), Gaps = 9/138 (6%)
Query: 479 PHERLGHFSQRPWSALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQ 538
P + G + P A A +P G+ P P +PP P P+ + AT
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP-TPPAVTPPSPKGTPTLPATT 1353
Query: 539 PCPRRAWTACETWEDPGPRLRNPLERPSPPAQRPWSSSGVQRAGPQGKGRGIGSPVSAAK 598
P + T + E P P P + P P G P+ G P S A
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK------GDPTSPA- 1406
Query: 599 HALPRPTGSFPQNPLGKE 616
+P P P+ +E
Sbjct: 1407 -VIPLSPKKAPATPVTRE 1423
Score = 32.0 bits (71), Expect = 2.8
Identities = 31/118 (26%), Positives = 42/118 (35%), Gaps = 20/118 (16%)
Query: 2 PTLVVGTPPTCLGDTPQPCHKNSQRQG----PFSHGAPGRAADWKAVAKPRLCAPAAEDD 57
PT TPP+ G P HK + P G P + A P P+ +
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Query: 58 VAALRWPGPSQQPDPPWAAPHVVGSDDLKEPGPWGKACSLPMWSTGPEARDGDSSVSS 115
P P P PP P P P G +LP +T P ++ G ++ SS
Sbjct: 1324 PGT---PPPKGAPTPPAVTP----------PSPKGTP-TLP--ATTPSSKGGPTTPSS 1365
Score = 31.2 bits (69), Expect = 4.8
Identities = 40/147 (27%), Positives = 51/147 (34%), Gaps = 14/147 (9%)
Query: 493 ALAGQACSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVATQPCPRRAWTACETWE 552
+L G P + + GP++ P P + P P +AT P T T
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134
Query: 553 DPGPRLRNPLER--PSPPAQRPWSSSGVQRAGPQGKGR----GIGSPVSAAKHALPRPTG 606
P L P + P+ PA P S G A P KG P A P P G
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPSPKG 1193
Query: 607 SFPQNPLGKEKDTLRPCPRSRGLLGPS 633
+ P P P P+ GL PS
Sbjct: 1194 A-PTTPAATP-----PSPKG-GLATPS 1213
>gi|239753377 PREDICTED: hypothetical protein [Homo sapiens]
Length = 328
Score = 38.9 bits (89), Expect = 0.023
Identities = 40/154 (25%), Positives = 54/154 (35%), Gaps = 14/154 (9%)
Query: 483 LGHFSQRPWSALA-GQA-----CSPQRAWGAQRQGPSSQRPGSPPEKRSPFPQQPWSAVA 536
+GH S P LA G A CSP Q + ++PG P Q P A A
Sbjct: 175 VGHLSHVPGQGLAQGDADGLTGCSPSPGHPEQAESSQGKQPG-------PQQQHPSRAAA 227
Query: 537 TQPCPRRAWTACETWEDPGPRLRNPLERPS-PPAQRPWSSSGVQRAGPQGKGRGIGSPVS 595
R A W GP R L R +SS G R G+ +
Sbjct: 228 DHDPGRMGQGAAAQWTPKGPLRRLRLPRCKWTQGSGSFSSPGNHRFLGSNSPNGVPRALP 287
Query: 596 AAKHALPRPTGSFPQNPLGKEKDTLRPCPRSRGL 629
++ H RP SFP + + ++ P R +
Sbjct: 288 SSSHRPCRPGCSFPTSKPSEAATSIYSSPSGRSI 321
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,996,920
Number of Sequences: 37866
Number of extensions: 2870860
Number of successful extensions: 11992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 479
Number of HSP's that attempted gapping in prelim test: 10870
Number of HSP's gapped (non-prelim): 1624
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.