Guide to the Human Genome
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Search of human proteins with 42560231

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo
sapiens]
         (458 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]    932   0.0  
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]    691   0.0  
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]    684   0.0  
gi|112789532 poliovirus receptor related 2 isoform delta precurs...   208   9e-54
gi|11386199 poliovirus receptor-related 3 [Homo sapiens]              208   9e-54
gi|5360210 poliovirus receptor related 2 isoform alpha precursor...   200   2e-51
gi|209413732 poliovirus receptor isoform delta [Homo sapiens]         183   3e-46
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]         183   3e-46
gi|209413728 poliovirus receptor isoform beta [Homo sapiens]          178   1e-44
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]         174   1e-43
gi|222136611 poliovirus receptor-related 4 [Homo sapiens]             150   3e-36
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]         82   1e-15
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          82   1e-15
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho...    81   2e-15
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho...    78   2e-14
gi|21686977 cell adhesion molecule 4 [Homo sapiens]                    70   5e-12
gi|90903245 CD200 antigen isoform b [Homo sapiens]                     69   9e-12
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]           69   9e-12
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]       65   1e-10
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   63   6e-10
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             62   8e-10
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]               62   1e-09
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]                62   1e-09
gi|68161541 carcinoembryonic antigen-related cell adhesion molec...    59   7e-09
gi|19923195 carcinoembryonic antigen-related cell adhesion molec...    59   9e-09
gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho...    58   2e-08
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    56   6e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    56   6e-08
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    56   6e-08
gi|166295173 kin of IRRE like [Homo sapiens]                           55   1e-07

>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
          Length = 458

 Score =  932 bits (2409), Expect = 0.0
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
           MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV
Sbjct: 1   MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60

Query: 61  KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
           KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG
Sbjct: 61  KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120

Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
           VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP
Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180

Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
           SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240

Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
           LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL
Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300

Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAARLLAGTVAVFLIL 360
           FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAARLLAGTVAVFLIL
Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAARLLAGTVAVFLIL 360

Query: 361 VAVLTVFFLYNRQQKSPPETDGAGTDQPLSQKPEPSPSRQSSLVPEDIQVVHLDPGRQQQ 420
           VAVLTVFFLYNRQQKSPPETDGAGTDQPLSQKPEPSPSRQSSLVPEDIQVVHLDPGRQQQ
Sbjct: 361 VAVLTVFFLYNRQQKSPPETDGAGTDQPLSQKPEPSPSRQSSLVPEDIQVVHLDPGRQQQ 420

Query: 421 QEEEDLQKLSLQPPYYDLGVSPSYHPSVRTTEPRGECP 458
           QEEEDLQKLSLQPPYYDLGVSPSYHPSVRTTEPRGECP
Sbjct: 421 QEEEDLQKLSLQPPYYDLGVSPSYHPSVRTTEPRGECP 458


>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
          Length = 517

 Score =  691 bits (1782), Expect = 0.0
 Identities = 344/370 (92%), Positives = 350/370 (94%), Gaps = 6/370 (1%)

Query: 1   MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
           MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV
Sbjct: 1   MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60

Query: 61  KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
           KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG
Sbjct: 61  KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120

Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
           VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP
Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180

Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
           SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240

Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
           LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL
Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300

Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP----RPQRG--LGSAARLLAGTV 354
           FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITE P     P+ G   G     + G V
Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGV 360

Query: 355 AVFLILVAVL 364
           A  ++LV ++
Sbjct: 361 AGSILLVLIV 370


>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
          Length = 352

 Score =  684 bits (1764), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
           MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV
Sbjct: 1   MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60

Query: 61  KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
           KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG
Sbjct: 61  KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120

Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
           VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP
Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180

Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
           SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240

Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
           LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL
Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300

Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
           FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT
Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334


>gi|112789532 poliovirus receptor related 2 isoform delta precursor
           [Homo sapiens]
          Length = 538

 Score =  208 bits (529), Expect = 9e-54
 Identities = 145/444 (32%), Positives = 209/444 (47%), Gaps = 43/444 (9%)

Query: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89

Query: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149

Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204

Query: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262

Query: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321

Query: 309 SLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAARLLAGTVAVFLILVAVLTVFF 368
               T++C  TN +G    +  + + E P    G G+   ++ G +A  +I  AV     
Sbjct: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETPN-TAGAGATGGIIGGIIAA-IIATAVAATGI 379

Query: 369 LYNRQQKSPPETDGAGTDQPLSQKPE-PSPSRQSSLVPEDIQVVHLDPGRQQQQEEEDLQ 427
           L  RQQ+      GA  D+ L   P    P+ ++ L  +++       G  +        
Sbjct: 380 LICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHS------ 433

Query: 428 KLSLQPPYYDLGVS------PSYH 445
              L+ PY+D G S      P YH
Sbjct: 434 --PLKTPYFDAGASCTEQEMPRYH 455


>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
          Length = 549

 Score =  208 bits (529), Expect = 9e-54
 Identities = 108/279 (38%), Positives = 162/279 (58%), Gaps = 8/279 (2%)

Query: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGV 121
           ITQ++W+K    S Q VA+++P  G SV   Y+ RV F   S  D TI L  +   D G 
Sbjct: 86  ITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGK 145

Query: 122 YICEFATFPTGNRESQLNLTVMAKPT-NWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
           YIC+  TFP GN +S   +TV+ +PT + I+G  +++       ++ + A C +A GKP 
Sbjct: 146 YICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDG----GNETVAAICIAATGKPV 201

Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKES 238
           + + WE  L GE E      PN T T+IS+Y+L P+R A  + + C+V +       + S
Sbjct: 202 AHIDWEGDL-GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260

Query: 239 LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNR 298
             L++QY PEV++ G+DGNW++ R  V L C ADANPP  +  W+ L+G  P G+ A + 
Sbjct: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDN 320

Query: 299 TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
           TL F  P+ ++ +G YIC+ TN +G RS Q  + I++ P
Sbjct: 321 TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPP 359


>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
           [Homo sapiens]
          Length = 479

 Score =  200 bits (509), Expect = 2e-51
 Identities = 144/436 (33%), Positives = 208/436 (47%), Gaps = 38/436 (8%)

Query: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89

Query: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149

Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204

Query: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262

Query: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321

Query: 309 SLAGTYICEATNPIGTRSGQVEVNITEKPRPQ-RGLGSAA-RLLAGTVAVFLILVAVLTV 366
               T++C  TN +G    +  + + E PR   R +G      + GT+ V L+L      
Sbjct: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGGSLA 381

Query: 367 FFL--YNRQQKSP------PETDGAGTDQPLSQKPEPSPSRQSSLVPEDIQVVHLDPGRQ 418
           F L    R++KSP         DG   D          P   + +VP  ++    D   +
Sbjct: 382 FILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDPVFWTPVVPGPMEPDGKD--EE 439

Query: 419 QQQEEEDLQKLSLQPP 434
           +++EEE  +K  + PP
Sbjct: 440 EEEEEEKAEKGLMLPP 455


>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
          Length = 392

 Score =  183 bits (464), Expect = 3e-46
 Identities = 126/377 (33%), Positives = 192/377 (50%), Gaps = 25/377 (6%)

Query: 6   LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
           +A A    W L   AL + ++  PG    VVQ    + GF+G  V L C    P   V  
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
           ++Q+TW +  +G   ++A+++ + G S      +R+EF    L     + ++R+  L +E
Sbjct: 61  VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116

Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
           DEG Y C F TFP G+R   + L V+AKP N  E  +  L       + V +A C S  G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171

Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
           +PP+ ++W + L G     ++    +GTVTV S + LVPS +   +++ C V +      
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231

Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
           + LT+N  V Y PEV+I G+D NWYL + +  LTC A +NP  T Y+W+T  G LP    
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291

Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLG---SAARLLA 351
           AQ   L  + P++  +  T IC  TN +G R  ++ V + E P P    G   +A   L 
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP-PSEHSGISRNAIIFLV 349

Query: 352 GTVAVFLILVAVLTVFF 368
             + VFLIL+ +   F+
Sbjct: 350 LGILVFLILLGIGIYFY 366


>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
          Length = 417

 Score =  183 bits (464), Expect = 3e-46
 Identities = 126/377 (33%), Positives = 192/377 (50%), Gaps = 25/377 (6%)

Query: 6   LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
           +A A    W L   AL + ++  PG    VVQ    + GF+G  V L C    P   V  
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
           ++Q+TW +  +G   ++A+++ + G S      +R+EF    L     + ++R+  L +E
Sbjct: 61  VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116

Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
           DEG Y C F TFP G+R   + L V+AKP N  E  +  L       + V +A C S  G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171

Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
           +PP+ ++W + L G     ++    +GTVTV S + LVPS +   +++ C V +      
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231

Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
           + LT+N  V Y PEV+I G+D NWYL + +  LTC A +NP  T Y+W+T  G LP    
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291

Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLG---SAARLLA 351
           AQ   L  + P++  +  T IC  TN +G R  ++ V + E P P    G   +A   L 
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP-PSEHSGISRNAIIFLV 349

Query: 352 GTVAVFLILVAVLTVFF 368
             + VFLIL+ +   F+
Sbjct: 350 LGILVFLILLGIGIYFY 366


>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
          Length = 372

 Score =  178 bits (451), Expect = 1e-44
 Identities = 116/343 (33%), Positives = 177/343 (51%), Gaps = 21/343 (6%)

Query: 6   LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
           +A A    W L   AL + ++  PG    VVQ    + GF+G  V L C    P   V  
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
           ++Q+TW +  +G   ++A+++ + G S      +R+EF    L     + ++R+  L +E
Sbjct: 61  VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116

Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
           DEG Y C F TFP G+R   + L V+AKP N  E  +  L       + V +A C S  G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171

Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
           +PP+ ++W + L G     ++    +GTVTV S + LVPS +   +++ C V +      
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231

Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
           + LT+N  V Y PEV+I G+D NWYL + +  LTC A +NP  T Y+W+T  G LP    
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291

Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
           AQ   L  + P++  +  T IC  TN +G R  ++ V + E P
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP 333


>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
          Length = 364

 Score =  174 bits (442), Expect = 1e-43
 Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%)

Query: 6   LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
           +A A    W L   AL + ++  PG    VVQ    + GF+G  V L C    P   V  
Sbjct: 1   MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60

Query: 62  ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
           ++Q+TW +  +G   ++A+++ + G S      +R+EF    L     + ++R+  L +E
Sbjct: 61  VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116

Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
           DEG Y C F TFP G+R   + L V+AKP N  E  +  L       + V +A C S  G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171

Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
           +PP+ ++W + L G     ++    +GTVTV S + LVPS +   +++ C V +      
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231

Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
           + LT+N  V Y PEV+I G+D NWYL + +  LTC A +NP  T Y+W+T  G LP    
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291

Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
           AQ   L  + P++  +  T IC  TN +G R  ++ V +
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329


>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
          Length = 510

 Score =  150 bits (378), Expect = 3e-36
 Identities = 128/442 (28%), Positives = 211/442 (47%), Gaps = 41/442 (9%)

Query: 4   MGLAGAAGRW----WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPS 59
           M L+  A  W    W L L L A F     +  ++ +D +   +G D  L C +      
Sbjct: 1   MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SG 59

Query: 60  VKITQVTWQKSTNGS-KQNVAIYNPSMGVSVLAPYRERVEFLRPSFT--DGTIRLSRLEL 116
            ++ QV W +   G   Q +A+ +   G+ V   Y  RVE   P     DG++ L     
Sbjct: 60  EQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQ 119

Query: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
            DEG Y C  +TFP G+ +++L L V+  P   +    A+   ++GQ    L A+CT A 
Sbjct: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL---EEGQ-GLTLAASCT-AE 174

Query: 177 GKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
           G P   V+W+T +KG    +  ++ + +  V S + LVPSR  + Q L C+V++      
Sbjct: 175 GSPAPSVTWDTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233

Query: 237 ESLT--LNVQYEPEVTIEGFDGN--WYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
           + +T  L+V +  E ++ G +    W++ R    L C ++  PP + Y+WT L+G LP G
Sbjct: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSG 292

Query: 293 VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI---TEKPRPQRGLGSAARL 349
           V     TL F  P+    +G Y+C  +N   +R  QV V++    E    Q  L SA+ +
Sbjct: 293 VRVDGDTLGFP-PLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVV 351

Query: 350 LAGTVA--VFLILVAVLTVFFLYNRQQKSPPETDGAGTDQPLSQK--PEPSPSRQSSLVP 405
           + G +A  +F +LV V+ +   Y+R++            Q ++QK   E + +R++S+  
Sbjct: 352 VVGVIAALLFCLLVVVVVLMSRYHRRKA-----------QQMTQKYEEELTLTRENSI-- 398

Query: 406 EDIQVVHLDPGRQQQQEEEDLQ 427
             +   H DP R Q +E   L+
Sbjct: 399 RRLHSHHTDP-RSQPEESVGLR 419


>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
          Length = 398

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 78/283 (27%), Positives = 124/283 (43%), Gaps = 22/283 (7%)

Query: 96  RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
           R++ +  +  + +I +S + L DEG Y C   T P    +S +  L +  KP   I G +
Sbjct: 82  RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 139

Query: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
           + LR K           C S+  KP + ++W   +  L GE    QE  +PNG T TV S
Sbjct: 140 SSLREKD-----TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 192

Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLT---LNVQYEPEVTIEGFDGNWYLQRMDVK 266
                 +RE    S+ C VN+   +  +  T   + V Y P   I   D     +   + 
Sbjct: 193 SVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLL 251

Query: 267 LTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRS 326
           L C+   NP   +Y W    GS+P     Q   L F   +N S +GTY C AT+ +G+  
Sbjct: 252 LHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSYK 309

Query: 327 GQVEVNITEKPRPQRGLGSAARLLAGTVAVFLILVAVLTVFFL 369
               +N+ + P P     S    + G +  F++ + ++ + FL
Sbjct: 310 AYYTLNVND-PSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFL 351


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 78/283 (27%), Positives = 124/283 (43%), Gaps = 22/283 (7%)

Query: 96  RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
           R++ +  +  + +I +S + L DEG Y C   T P    +S +  L +  KP   I G +
Sbjct: 116 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 173

Query: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
           + LR K           C S+  KP + ++W   +  L GE    QE  +PNG T TV S
Sbjct: 174 SSLREKD-----TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 226

Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLT---LNVQYEPEVTIEGFDGNWYLQRMDVK 266
                 +RE    S+ C VN+   +  +  T   + V Y P   I   D     +   + 
Sbjct: 227 SVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLL 285

Query: 267 LTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRS 326
           L C+   NP   +Y W    GS+P     Q   L F   +N S +GTY C AT+ +G+  
Sbjct: 286 LHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSYK 343

Query: 327 GQVEVNITEKPRPQRGLGSAARLLAGTVAVFLILVAVLTVFFL 369
               +N+ + P P     S    + G +  F++ + ++ + FL
Sbjct: 344 AYYTLNVND-PSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFL 385


>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 82/326 (25%), Positives = 141/326 (43%), Gaps = 33/326 (10%)

Query: 78  VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
           + + NP+        +R     R + L  S ++  + L+ + + DEG Y C+  T P   
Sbjct: 74  IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131

Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
           +ES   +TV+  P N +   Q    A +G++ +V    CT+   KP + + W    T LK
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187

Query: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
           G++E +E    +   TV S+  L   +E     + C V +       +    L VQY+P+
Sbjct: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244

Query: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
           V I+     + LQ +      ++LTC+A   P      W  ++  +P+        LF  
Sbjct: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301

Query: 304 GPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAA--RLLAGTVAV----F 357
             +N +  GTY CEA+N +G       + + +    + G   A    ++ G VAV     
Sbjct: 302 N-LNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAM 360

Query: 358 LILVAVLTVFFLYNRQQKSPPETDGA 383
           L L+ +L  +F  ++      E  GA
Sbjct: 361 LCLLIILGRYFARHKGTYFTHEAKGA 386


>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 70/274 (25%), Positives = 121/274 (44%), Gaps = 27/274 (9%)

Query: 78  VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
           + + NP+        +R     R + L  S ++  + L+ + + DEG Y C+  T P   
Sbjct: 74  IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131

Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
           +ES   +TV+  P N +   Q    A +G++ +V    CT+   KP + + W    T LK
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187

Query: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
           G++E +E    +   TV S+  L   +E     + C V +       +    L VQY+P+
Sbjct: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244

Query: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
           V I+     + LQ +      ++LTC+A   P      W  ++  +P+        LF  
Sbjct: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301

Query: 304 GPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
             +N +  GTY CEA+N +G       + + + P
Sbjct: 302 N-LNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334


>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
          Length = 388

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 86/328 (26%), Positives = 133/328 (40%), Gaps = 34/328 (10%)

Query: 78  VAIYNPSM------GVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPT 131
           V I NP+       G   L   R ++E   P      IRLS   LEDEG Y C+  T  T
Sbjct: 54  VVIQNPARQTLFFNGTRALKDERFQLEEFSPRRV--RIRLSDARLEDEGGYFCQLYTEDT 111

Query: 132 GNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETR 188
            ++ +   LTV+  P N +   +   +A +G + ++   +C     +P + + W      
Sbjct: 112 HHQIA--TLTVLVAPENPVVEVRE--QAVEGGEVEL---SCLVPRSRPAATLRWYRDRKE 164

Query: 189 LKGEAEYQEIRNPNGTV-TVISRYRLVPSREAHQQSLACIVNYHM----DRFKESLTLNV 243
           LKG +  QE    NG V +V S  R    R+     + C             +    L+V
Sbjct: 165 LKGVSSSQE----NGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDV 220

Query: 244 QYEPEVTIEGFDGNWYLQRMD-VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFF 302
           QY P   I        ++  D + LTC    NP   +  W   N SLP+  EA   TL  
Sbjct: 221 QYSPTARIHASQA--VVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTL 278

Query: 303 KGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAARLLAG---TVAVFLI 359
            G ++    GTY CEA+N  G       + + +         S    + G    + VFLI
Sbjct: 279 PGLVSAD-NGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLI 337

Query: 360 LVAVLTVFFLYNRQQKSPPETDGAGTDQ 387
           +  ++ + +   RQ+ S    + +G D+
Sbjct: 338 ICVLVGMVWCSVRQKGSYLTHEASGLDE 365


>gi|90903245 CD200 antigen isoform b [Homo sapiens]
          Length = 294

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 14/185 (7%)

Query: 45  TDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSF 104
           T   L CS  N   ++    VTWQK    S +N+  ++ + GV +   Y++++   +   
Sbjct: 70  TPASLKCSLQNAQEALI---VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGL 126

Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164
            + TI    + LEDEG Y+C F TF  G       LTV  +P          L  K  +D
Sbjct: 127 QNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPI-------VSLHYKFSED 179

Query: 165 DKVLVATCTSANGKPPSVVSWETRLKG-EAEYQEIRNPNGTVTVISRYRLVPSREAHQQS 223
              L  TC SA  +P  +V W+    G E     + +PNGT +V S   +   +    + 
Sbjct: 180 H--LNITC-SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKE 236

Query: 224 LACIV 228
           + C V
Sbjct: 237 VICQV 241


>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
          Length = 269

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 14/185 (7%)

Query: 45  TDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSF 104
           T   L CS  N   ++    VTWQK    S +N+  ++ + GV +   Y++++   +   
Sbjct: 45  TPASLKCSLQNAQEALI---VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGL 101

Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164
            + TI    + LEDEG Y+C F TF  G       LTV  +P          L  K  +D
Sbjct: 102 QNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPI-------VSLHYKFSED 154

Query: 165 DKVLVATCTSANGKPPSVVSWETRLKG-EAEYQEIRNPNGTVTVISRYRLVPSREAHQQS 223
              L  TC SA  +P  +V W+    G E     + +PNGT +V S   +   +    + 
Sbjct: 155 H--LNITC-SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKE 211

Query: 224 LACIV 228
           + C V
Sbjct: 212 VICQV 216


>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
          Length = 437

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 64/252 (25%), Positives = 104/252 (41%), Gaps = 20/252 (7%)

Query: 96  RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
           R+E +R S+ + +I +S + L DEG Y C   T P   + S+  LTV+  P    E  Q 
Sbjct: 78  RIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPV--KTSKAYLTVLGVP----EKPQI 131

Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGEAEYQEIRNPNGTVTVISRYR 212
              +    +  ++  TC ++  KP + + W   +  +K     +E      T TV S   
Sbjct: 132 SGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLD 191

Query: 213 LVPSREAHQQSLACIVNYHMDRFKESL---TLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
               R     ++ C V++        +    L + Y P V I      +  +   + LTC
Sbjct: 192 FRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIP-STPFPQEGQPLILTC 250

Query: 270 KADANPPATEYHWTTLNGSLPKG----VEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325
           ++   P      WT   G LP      V  +   + F   +N +  GTY CEATN IG  
Sbjct: 251 ESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILF---LNKTDNGTYRCEATNTIGQS 307

Query: 326 SGQVEVNITEKP 337
           S +  + + + P
Sbjct: 308 SAEYVLIVHDVP 319


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 69/248 (27%), Positives = 107/248 (43%), Gaps = 37/248 (14%)

Query: 104 FTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNL----TVMAKPTNWIEGTQAVLRA 159
           F DGT+ +      D+GVY C  A    G  ++Q  +    ++ AKP+  I+        
Sbjct: 285 FDDGTLMIRNTRESDQGVYQC-MARNSAGEAKTQSAMLRYSSLPAKPSFVIQ-------- 335

Query: 160 KKGQDDKVLVATCTS----ANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVP 215
              QD +VL+ T T+    A G P  +++W TR  G     E+       T    Y    
Sbjct: 336 --PQDTEVLIGTSTTLECMATGHPHPLITW-TRDNG----LELDGSRHVATSSGLYLQNI 388

Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANP 275
           ++  H +   C  N      + +  + VQ  P+ T+   D    L+   V+  C+AD NP
Sbjct: 389 TQRDHGR-FTCHANNSHGTVQAAANIIVQAPPQFTVTPKD-QVVLEEHAVEWLCEADGNP 446

Query: 276 PATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYICEATNPIGTRSGQVE 330
           P     WT   G LP  VE Q+ T+   G +    A     G Y C+A + +G +  +V 
Sbjct: 447 PPV-IVWTKTGGQLP--VEGQH-TVLSSGTLRIDRAAQHDQGQYECQAVSSLGVK--KVS 500

Query: 331 VNITEKPR 338
           V +T KP+
Sbjct: 501 VQLTVKPK 508



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 65  VTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYIC 124
           V W    +G+   V ++  + G       +  VE      + GT+R+ R    D+G Y C
Sbjct: 436 VEWLCEADGNPPPVIVWTKTGG-------QLPVEGQHTVLSSGTLRIDRAAQHDQGQYEC 488

Query: 125 EFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVS 184
           + A    G ++  + LTV  K              + G++  +   +C  A G+P  +++
Sbjct: 489 Q-AVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINI---SC-HAQGEPQPIIT 543

Query: 185 W 185
           W
Sbjct: 544 W 544


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 74/309 (23%), Positives = 124/309 (40%), Gaps = 40/309 (12%)

Query: 47   VVLHCSFANPLPSVKITQVTWQKS-----TNGSKQNVAIYNPSMGVSVLAPYRERVEFLR 101
            V +  S   P+P+  + Q  + ++     T G   ++    P    + +  Y+       
Sbjct: 2908 VTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPA 2967

Query: 102  PSFTDGT-IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA- 159
               T G+ +RL  +   D G Y+C  A+ P   +E+   +TV        EG+   LR+ 
Sbjct: 2968 RHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPS-----EGSSYRLRSP 3022

Query: 160  -----------KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVI 208
                       ++GQD       C   +G  P  + W+TR + E E     +PNG++  I
Sbjct: 3023 VISIDPPSSTVQQGQDASF---KCLIHDGAAPISLEWKTRNQ-ELEDNVHISPNGSIITI 3078

Query: 209  SRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLT 268
                 V +R ++  +  C+ +      +  + L+V   P V++      W      V L 
Sbjct: 3079 -----VGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLE 3133

Query: 269  CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPI------NYSLAGTYICEATNPI 322
            C   A  P +   WT ++ S P  +E +   L     +        S AGTY+C A N +
Sbjct: 3134 C-VSAGEPRSSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191

Query: 323  GTRSGQVEV 331
            GT   QVEV
Sbjct: 3192 GTAQKQVEV 3200



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 75/328 (22%), Positives = 121/328 (36%), Gaps = 60/328 (18%)

Query: 20   LTAFFLPGVHSQVVQVNDSMYG-FIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNV 78
            L A  +P   +  VQV   +    IG  V  HC+    +PS + TQ+ W K         
Sbjct: 3389 LPATSIPAGSTPTVQVTPQLETKSIGASVEFHCA----VPSDRGTQLRWFKEGGQ----- 3439

Query: 79   AIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQL 138
                       L P          S  DG +R+  L+   +G YIC+ A  P G  ++  
Sbjct: 3440 -----------LPPGH--------SVQDGVLRIQNLDQSCQGTYICQ-AHGPWGKAQASA 3479

Query: 139  NLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEI 198
             L + A P+  I    +V     G      V     A G P   V+W +++ G      +
Sbjct: 3480 QLVIQALPSVLINIRTSVQTVVVGH----AVEFECLALGDPKPQVTW-SKVGGHLRPGIV 3534

Query: 199  RNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNW 258
            ++  G V  I+   L  + +       C         +  + L VQ  P++++       
Sbjct: 3535 QS--GGVVRIAHVELADAGQYR-----CTATNAAGTTQSHVLLLVQALPQISMP------ 3581

Query: 259  YLQRMDVKLTCKADA-------NPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA 311
                 +V++   + A         P  +  W+ L+GSLP     +N  L     +    A
Sbjct: 3582 ----QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPS-VRPQDA 3636

Query: 312  GTYICEATNPIGTRSGQVEVNITEKPRP 339
            GTY+C ATN  G       + + E+  P
Sbjct: 3637 GTYVCTATNRQGKVKAFAHLQVPERVVP 3664



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 54/235 (22%), Positives = 90/235 (38%), Gaps = 24/235 (10%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTV----MAKPTNWIEGTQAVLRAKKGQD 164
            +++S  +  D G Y+C  A    G  + Q+ + V    MA     ++  +A L  + G  
Sbjct: 3170 LQISSAKPSDAGTYVC-LAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGH- 3227

Query: 165  DKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQS- 223
                   C SA G P   + W           ++R+P      +    L+  R A Q S 
Sbjct: 3228 --TATLRC-SATGSPAPTIHWS----------KLRSPLPWQHRLEGDTLIIPRVAQQDSG 3274

Query: 224  -LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHW 282
               C         + ++ L+V+  P  T      +       V+L C A   PP T + W
Sbjct: 3275 QYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGET-VQLQCLAHGTPPLT-FQW 3332

Query: 283  TTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
            + +  SLP    A+N  L F+       +G Y C  TN +G+     ++ +   P
Sbjct: 3333 SRVGSSLPGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAEAFAQLLVQGPP 3386



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 77/318 (24%), Positives = 116/318 (36%), Gaps = 42/318 (13%)

Query: 106  DGTIRLSRLELEDEGVYICEFATF-----PTGNRESQLNLTVMAKPTNWIEGTQAVLRAK 160
            +G + +  ++L D G Y+C  +        T     Q + T+ A P   I   Q  L  +
Sbjct: 1822 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSA-PVVSIHPPQ--LTVQ 1878

Query: 161  KGQDDKVLVATCTSANGKPPSVVSW------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214
             GQ    L     SA G P   + W      +   K +     +R P    T  ++Y   
Sbjct: 1879 PGQ----LAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCR 1934

Query: 215  PSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADAN 274
                A QQ    +++ H           VQ  PE T +   G        V+L C+A   
Sbjct: 1935 AHSSAGQQVARAVLHVHGGGGPR-----VQVSPERT-QVHAGR------TVRLYCRAAGV 1982

Query: 275  PPATEYHWTTLNGSLPKGVEAQNRTL--FFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332
            P AT   W    GSLP    ++   +       I  + AG Y+C AT+P GT   +++V 
Sbjct: 1983 PSAT-ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVV 2041

Query: 333  ITE----KPRPQRGLGSAARLLAGTVAVFLILVA--VLTVFFLYNRQQKSPPETDGAGTD 386
            +       P P +   S+  +  G       +VA         Y R    PP T   G+ 
Sbjct: 2042 VLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR 2101

Query: 387  QPLSQKPEPSPSRQSSLV 404
              L   P+ SP+     V
Sbjct: 2102 LRL---PQVSPADSGEYV 2116



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 53/233 (22%), Positives = 89/233 (38%), Gaps = 31/233 (13%)

Query: 118  DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
            + G Y C  A+   G  +S +NL+V   PT  +   +  +  K G   K +   C SA G
Sbjct: 3085 NHGTYRC-VASNAYGVAQSVVNLSVHGPPTVSVL-PEGPVWVKVG---KAVTLECVSA-G 3138

Query: 178  KPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKE 237
            +P S   W TR+       E R   G +   +  ++  ++ +   +  C+    +   ++
Sbjct: 3139 EPRSSARW-TRISSTPAKLEQRT-YGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK 3196

Query: 238  SLTLNVQY-------------EPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTT 284
             + + V               E E+T+E              L C A  +P  T  HW+ 
Sbjct: 3197 QVEVIVDTGAMAPGAPQVQAEEAELTVEAGH--------TATLRCSATGSPAPT-IHWSK 3247

Query: 285  LNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
            L   LP     +  TL          +G YIC AT+P G     + +++   P
Sbjct: 3248 LRSPLPWQHRLEGDTLIIPRVAQQD-SGQYICNATSPAGHAEATIILHVESPP 3299



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 264  DVKLTCKADANPPATEYHWTTL-NGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPI 322
            DV   C A +  PA    WT L NG LP      N  L  +  +  S AGTY+C  +N  
Sbjct: 1788 DVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRN-VQLSDAGTYVCTGSNMF 1846

Query: 323  GTRSGQVEVNI 333
                G   +++
Sbjct: 1847 AMDQGTATLHV 1857



 Score = 35.8 bits (81), Expect = 0.083
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 265  VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGT 324
            V+  C A    P  +  W+ + G L  G+  Q+  +     +  + AG Y C ATN  GT
Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVGGHLRPGI-VQSGGVVRIAHVELADAGQYRCTATNAAGT 3563

Query: 325  RSGQVEVNITEKPRPQRGLGSAARLLAGTVAVF 357
               Q  V +  +  PQ  +    R+ AG+ AVF
Sbjct: 3564 T--QSHVLLLVQALPQISMPQEVRVPAGSAAVF 3594



 Score = 32.7 bits (73), Expect = 0.70
 Identities = 56/258 (21%), Positives = 93/258 (36%), Gaps = 43/258 (16%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTV-----------MAKPTNWIEGTQAVL 157
            +RL ++   D G Y+C      +G +E+ + +T+           +A P   IE + A L
Sbjct: 2488 LRLLQVTPADSGEYVCRVVG-SSGTQEASVLVTIQQRLSGSHSQGVAYPVR-IESSSASL 2545

Query: 158  RAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSR 217
                  D   LVA+      + P  ++W  R        +I        V SR R+    
Sbjct: 2546 ANGHTLDLNCLVAS------QAPHTITWYKRGGSLPSRHQI--------VGSRLRIPQVT 2591

Query: 218  EAHQQSLACIVNYHMDRFKESLTLNVQ---------YEPEVTIEGFDGNWYLQRMDVKLT 268
             A      C V+      + SL + +Q           P + IE       ++   + L 
Sbjct: 2592 PADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT-VVEGQTLDLN 2650

Query: 269  CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328
            C     P A    W    GSLP   +     L     ++ + +G Y+C A N I      
Sbjct: 2651 CVVARQPQAI-ITWYKRGGSLPSRHQTHGSHLRLH-QMSVADSGEYVCRANNNIDALEAS 2708

Query: 329  VEVNITEKPRPQRGLGSA 346
            + ++++    P  G  SA
Sbjct: 2709 IVISVS----PSAGSPSA 2722



 Score = 32.3 bits (72), Expect = 0.92
 Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 3/73 (4%)

Query: 267  LTCKADANPPATEYHWTTLNGS-LPKGVEAQNRTLFFKGP-INYSLAGTYICEATNPIGT 324
            L C+   +PP   ++W+  +G  +P G + +++      P +  S AG YIC   N   +
Sbjct: 1696 LRCQVSGSPPHY-FYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQS 1754

Query: 325  RSGQVEVNITEKP 337
             + + E+ +TE P
Sbjct: 1755 NTSRAELLVTEAP 1767


>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
          Length = 600

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 57/239 (23%), Positives = 101/239 (42%), Gaps = 23/239 (9%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           +++ R EL+D+ VY C+        R     LTV+  P + +     V+  + G     L
Sbjct: 112 LKILRAELQDDAVYECQ--AIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDP---L 166

Query: 169 VATCTSANGKPPSVVSWETR---LKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225
             TC + N KP + + W  +   + G    + +       +++S   + P    + QS+ 
Sbjct: 167 NLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIV 226

Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
           C   N  +   KE S+T+++Q+ P V +   +    L+   V   C A ANP  T+Y W 
Sbjct: 227 CRATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRWA 285

Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPR 338
                + +      RT     +F  P++        CE TN +G+ +    V++   PR
Sbjct: 286 KRGQIIKEASGEVYRTTVDYTYFSEPVS--------CEVTNALGSTNLSRTVDVYFGPR 336



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 13/114 (11%)

Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
           T+ L  +  ED G Y+C       G  E ++ LTV   P      TQ  L  +KGQ    
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQ---- 437

Query: 168 LVATCTSANGKPPSVVSW-------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214
               C   +  PP  ++W       E+   G    + I    G ++ ++   +V
Sbjct: 438 --IKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489


>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
          Length = 778

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 57/239 (23%), Positives = 101/239 (42%), Gaps = 23/239 (9%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           +++ R EL+D+ VY C+        R     LTV+  P + +     V+  + G     L
Sbjct: 112 LKILRAELQDDAVYECQ--AIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDP---L 166

Query: 169 VATCTSANGKPPSVVSWETR---LKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225
             TC + N KP + + W  +   + G    + +       +++S   + P    + QS+ 
Sbjct: 167 NLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIV 226

Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
           C   N  +   KE S+T+++Q+ P V +   +    L+   V   C A ANP  T+Y W 
Sbjct: 227 CRATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRWA 285

Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPR 338
                + +      RT     +F  P++        CE TN +G+ +    V++   PR
Sbjct: 286 KRGQIIKEASGEVYRTTVDYTYFSEPVS--------CEVTNALGSTNLSRTVDVYFGPR 336



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 13/114 (11%)

Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
           T+ L  +  ED G Y+C       G  E ++ LTV   P      TQ  L  +KGQ    
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQ---- 437

Query: 168 LVATCTSANGKPPSVVSW-------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214
               C   +  PP  ++W       E+   G    + I    G ++ ++   +V
Sbjct: 438 --IKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489


>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 2 precursor [Homo sapiens]
          Length = 464

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 79/333 (23%), Positives = 119/333 (35%), Gaps = 32/333 (9%)

Query: 54  ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSR 113
           +NP+        T +  T  +     I N S+ VS           L+ S  + T+ L  
Sbjct: 154 SNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPR---------LQLSNGNRTLTLLS 204

Query: 114 LELEDEGVYICEFATFPTGNRESQLNLTVMAKP-TNWIEGTQAVLRAKKGQDDKVLVATC 172
           +   D G Y CE     + NR   + L V   P T  I  +    R         L  +C
Sbjct: 205 VTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGAN-----LSLSC 259

Query: 173 TSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM 232
            +A+  PP+  SW      +   QE+  PN TV     Y    +      +   +    +
Sbjct: 260 YAASN-PPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIV 318

Query: 233 DRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
                 +        + T+ G        +  V LTC    N       W   N SLP  
Sbjct: 319 TELSPVVAKPQIKASKTTVTG-------DKDSVNLTCST--NDTGISIRWFFKNQSLPSS 369

Query: 293 VE---AQNRTLFFKGPINYSLAGTYICEATNPIG-TRSGQVEVNITEKPRPQ-RGL--GS 345
                +Q  T     P+    AGTY CE  NPI   +S  + +N+     PQ  GL  G+
Sbjct: 370 ERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGA 429

Query: 346 AARLLAGTVAVFLILVAVLTVFFLYNRQQKSPP 378
            A ++ G VA+  ++   L  F  + +   S P
Sbjct: 430 IAGIVIGVVALVALIAVALACFLHFGKTGSSGP 462


>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 1 precursor [Homo sapiens]
          Length = 526

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 78/336 (23%), Positives = 121/336 (36%), Gaps = 32/336 (9%)

Query: 54  ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSR 113
           +NP+        T +  T  +     I N S+ VS           L+ S  + T+ L  
Sbjct: 154 SNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPR---------LQLSNGNRTLTLLS 204

Query: 114 LELEDEGVYICEFATFPTGNRESQLNLTVMAKP-TNWIEGTQAVLRAKKGQDDKVLVATC 172
           +   D G Y CE     + NR   + L V   P T  I  +    R         L  +C
Sbjct: 205 VTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGAN-----LSLSC 259

Query: 173 TSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM 232
            +A+  PP+  SW      +   QE+  PN TV     Y    +      +   +    +
Sbjct: 260 YAASN-PPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIV 318

Query: 233 DRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
                 +        + T+ G        +  V LTC    N       W   N SLP  
Sbjct: 319 TELSPVVAKPQIKASKTTVTG-------DKDSVNLTCST--NDTGISIRWFFKNQSLPSS 369

Query: 293 VE---AQNRTLFFKGPINYSLAGTYICEATNPIG-TRSGQVEVNITEKPRPQ-RGL--GS 345
                +Q  T     P+    AGTY CE  NPI   +S  + +N+     PQ  GL  G+
Sbjct: 370 ERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGA 429

Query: 346 AARLLAGTVAVFLILVAVLTVFFLYNRQQKSPPETD 381
            A ++ G VA+  ++   L  F  + +  ++  + D
Sbjct: 430 IAGIVIGVVALVALIAVALACFLHFGKTGRASDQRD 465


>gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo
           sapiens]
          Length = 602

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 69/291 (23%), Positives = 120/291 (41%), Gaps = 31/291 (10%)

Query: 150 IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
           ++G    L  +KGQ  ++L A    A+ +PP+ +SW      +       +P G  T+  
Sbjct: 268 LQGNVIYLEVQKGQFLRLLCA----ADSQPPATLSWVL----QDRVLSSSHPWGPRTLGL 319

Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPE-----------VTIEGFDGNW 258
             R V + ++ + +  C     +   +++L L+VQY PE             +E      
Sbjct: 320 ELRGVRAGDSGRYT--CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGT 377

Query: 259 ---YLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYI 315
               L+   ++L C   ++PPA    WT    ++     +    L    PI     G + 
Sbjct: 378 SLPVLEGQSLRLVCVTHSSPPA-RLSWTRWGQTVGPSQPSDPGVLELP-PIQMEHEGEFT 435

Query: 316 CEATNPIGTRSGQVEVNITEKPRPQRGLGSAARLLAGTVAVFLILVAVLTVFFL----YN 371
           C A +P+G++   + +++  K     GLG  A L AG VA  L   + L VF +      
Sbjct: 436 CHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAALGAG-VAALLAFCSCLVVFRVKICRKE 494

Query: 372 RQQKSPPETDGAGTDQPLSQKPEPSPSRQSSLVPEDIQVVHLDPGRQQQQE 422
            ++++  E D   T  P+SQ  +   S  SS            PG+ ++QE
Sbjct: 495 ARKRAAAEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQE 545


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 62/231 (26%), Positives = 94/231 (40%), Gaps = 17/231 (7%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           ++L R +  D GVY C+ A+   G  E    L V   PT  IEG        K    + +
Sbjct: 367 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 423

Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227
              C  A G P   +SW       AE  E R   +G+V      RL    EA     +C+
Sbjct: 424 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 477

Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
            +          ++ VQ  P++ + EG      +    ++L C+A  +P  T   W   N
Sbjct: 478 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 535

Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
           G   +   GV+ A   T      +    +G + C+ATN  GT   +VEV++
Sbjct: 536 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 586



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 60/250 (24%), Positives = 99/250 (39%), Gaps = 19/250 (7%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            + +   ++ D+G+Y C+ +    G       LTV   PT     T+ V +         L
Sbjct: 1897 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 1951

Query: 169  VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
            V TC   +G P   V+W   LK      E    +G V+   R +L   + A   +  C+ 
Sbjct: 1952 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 2006

Query: 229  NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287
                   ++   + V   P +   G     + L+  +V+L C+AD  PP  +  W     
Sbjct: 2007 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP-DVAWLKDGS 2065

Query: 288  SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQR 341
             L + +    R      +L  KG +  S AG Y C A NP G  +    VN+   P  ++
Sbjct: 2066 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 2124

Query: 342  GLGSAARLLA 351
            G   +  L++
Sbjct: 2125 GADGSGTLVS 2134



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 83/324 (25%), Positives = 119/324 (36%), Gaps = 54/324 (16%)

Query: 41  GFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFL 100
           G  G DV L C  +     V   QV W K     +Q V    P + V             
Sbjct: 229 GLAGADVELQCWTSG----VPTPQVEWTKD----RQPVLPGGPHLQVQ------------ 268

Query: 101 RPSFTDGTI-RLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA 159
                DG + R++   + DEG Y C  A  P G +     L V A PT W  G+      
Sbjct: 269 ----EDGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIW--GSNETGEV 321

Query: 160 KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISR----YRLVP 215
              +D   LV     A G P   ++W    K  A       P  T  V +R     +L  
Sbjct: 322 AVMEDH--LVQLLCEARGVPTPNITW---FKDGALL-----PTSTKVVYTRGGRQLQLGR 371

Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM----DVKLTCKA 271
           ++ +      C  +  +   +++  L+V   P  TIEG  G  Y+ +      V L C A
Sbjct: 372 AQSSDAGVYTCKASNAVGAAEKATRLDVYVPP--TIEGAGGRPYVVKAVAGRPVALECVA 429

Query: 272 DANP-PATEYHWTTLN--GSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328
             +P P   +H   L    S    +E     L  + P   S +G Y C A++P G    Q
Sbjct: 430 RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEAS-SGLYSCVASSPAGEAVLQ 488

Query: 329 --VEVNITEKPRPQRGLGSAARLL 350
             VEV +  +     GLG    ++
Sbjct: 489 YSVEVQVPPQLLVAEGLGQVTTIV 512



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 60/238 (25%), Positives = 92/238 (38%), Gaps = 25/238 (10%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           +++ +++L DEG+Y C  AT   G  + ++ L V+  P N   G        K   +   
Sbjct: 659 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 711

Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226
           V     A+G PP  VSW    KG   +Q + +  G TV+V  R  R+  ++ +   S  C
Sbjct: 712 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 765

Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
           + +      +    L V   P +T+        L    V+LTC A   P  T       N
Sbjct: 766 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 825

Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIGTRSGQVEVNITEKP 337
              P G         F G    +LA       G Y C A + +G     V + +   P
Sbjct: 826 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPP 880



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/243 (21%), Positives = 90/243 (37%), Gaps = 36/243 (14%)

Query: 107  GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158
            G +R++    ED G Y+C  A    G+   +  L V   P         +  EG+ A L 
Sbjct: 2809 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2867

Query: 159  AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218
             K              A G P   ++W+       + Q +    G  T+     L+    
Sbjct: 2868 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 2907

Query: 219  AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
              Q +    C     + R +  + L +   P  T     G+  L+  D + L C A  +P
Sbjct: 2908 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 2965

Query: 276  PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
                  WT  +  + +GV  Q+  +   +  ++   +GTY+C A N +G       V++ 
Sbjct: 2966 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 3024

Query: 335  EKP 337
            E P
Sbjct: 3025 EAP 3027



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 56/238 (23%), Positives = 83/238 (34%), Gaps = 26/238 (10%)

Query: 111  LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170
            L + +L  EG Y CE +    GN    L L V   P   I G +          D V   
Sbjct: 1031 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 1087

Query: 171  TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
             C +A GKPP  V+WE   +  G     +++N   ++ V        ++ AH    +C+ 
Sbjct: 1088 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 1140

Query: 229  NYHMDRFKESLTLNVQYEPEV--TIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
                 R +    L+V   PE+   ++            + L C+A   PP     W    
Sbjct: 1141 ENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPA-IRW--FR 1197

Query: 287  GSLPKGVEAQNRTLFFKGPINYSL-------AGTYICEATNPIGTRSGQVEVNITEKP 337
            G  P  V     T    G     +       +G Y C A+N  G       V +   P
Sbjct: 1198 GEEP--VSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPP 1253



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 72/314 (22%), Positives = 109/314 (34%), Gaps = 53/314 (16%)

Query: 37   DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95
            + +   + + V L C   A+P P     +VTW K +            S+G  V      
Sbjct: 1754 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 1793

Query: 96   RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
               FL P     T++L R  L D G+Y CE A    G  +  + L+V+  P        A
Sbjct: 1794 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 1839

Query: 156  VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
              +A +G  D VLV     A      +  P   V+W    +     Q  +   G      
Sbjct: 1840 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 1895

Query: 210  RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
            R  +  ++ + +   +C V+        + TL VQ  P       +    +    + LTC
Sbjct: 1896 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1955

Query: 270  KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATNPIGT 324
                 P  T    T L   +P    A +  +   G +  S      AGTY C A N    
Sbjct: 1956 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAE 2012

Query: 325  RSGQVEVNITEKPR 338
                  V +   PR
Sbjct: 2013 ARKDFVVAVLVAPR 2026



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 59/247 (23%), Positives = 90/247 (36%), Gaps = 27/247 (10%)

Query: 100  LRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--NWIEGTQAVL 157
            LR     G++ L  L   D G Y C  A  P G       + V+  PT     +G+   L
Sbjct: 2075 LRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGS-GTL 2132

Query: 158  RAKKGQDDKVLVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPS 216
             ++ G+    LV       G PP  VSW +  L      + + + +G    IS+ +L   
Sbjct: 2133 VSRPGE----LVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQL--- 2185

Query: 217  REAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
              A      C+          + TL VQ  P +    F  +  + R   V+L C+A    
Sbjct: 2186 --ADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEA-RGV 2242

Query: 276  PATEYHWTT-----LNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVE 330
            P     W       L+ SL +G   Q         +    +GTY C A +  G      +
Sbjct: 2243 PLPLVSWMKDGEPLLSQSLEQGPSLQLEA------VGAGDSGTYSCVAVSEAGEARRHFQ 2296

Query: 331  VNITEKP 337
            + + E P
Sbjct: 2297 LTVMEPP 2303



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 53/236 (22%), Positives = 84/236 (35%), Gaps = 21/236 (8%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           +R+ + +L D G Y C  A+   G+ E +  L V   P          +         VL
Sbjct: 750 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 799

Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223
           V T      +A G P   + W   LK          P   V    R   L  +R +    
Sbjct: 800 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 856

Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
            +C+    +   ++ + L V   P +  E  + +  +    V L C++ A PP     W 
Sbjct: 857 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 915

Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
                 P+ GV  + ++ L      +   AG Y CEA N  G       +N+   P
Sbjct: 916 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAP 971



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 54/261 (20%), Positives = 86/261 (32%), Gaps = 38/261 (14%)

Query: 90   LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149
            L P   R E L     +G++R+  +  +D G Y+C  A+   G+     +L V+  P   
Sbjct: 2522 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 2576

Query: 150  IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
               +   L A         +  C ++    P VV W+   K +   Q+            
Sbjct: 2577 PSPSNLTLTAHTPA-----LLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 2620

Query: 210  RYRLVPSREA--------HQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261
             YRL+PS                 C+V+  +        + V   P +  +  D    + 
Sbjct: 2621 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 2680

Query: 262  RMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYIC 316
               V LTC +   P  T   W+     L  G       +   G +    A     G Y C
Sbjct: 2681 A-PVVLTCHSTGIPAPT-VSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTC 2736

Query: 317  EATNPIGTRSGQVEVNITEKP 337
             A N  G     V + +   P
Sbjct: 2737 SARNSAGVAHKHVFLTVQASP 2757



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 63/312 (20%), Positives = 114/312 (36%), Gaps = 38/312 (12%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            +++ +  L   G Y C  A    G +     L+V+  PT        +L   +   D+ +
Sbjct: 1310 LQVLQANLSSAGHYSC-IAANAVGEKTKHFQLSVLLAPT--------ILGGAEDSADEEV 1360

Query: 169  VATCTS-------ANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQ 221
              T  +       A   P   ++W   +K  A ++  RN    +      +++ +++   
Sbjct: 1361 TVTVNNPISLICEALAFPSPNITW---MKDGAPFEASRNIQ-LLPGTHGLQILNAQKEDA 1416

Query: 222  QSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVK------LTCKADANP 275
                C+V   +    ++  + V   P ++ +   G   ++ +  K      L C++ A P
Sbjct: 1417 GQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVP 1476

Query: 276  PATEYHWTTLNGSLPKG---VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332
            P T   +       P     V  + R L  + P   S +G Y+C ATN  G       V 
Sbjct: 1477 PPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQ-PTQVSDSGRYLCVATNVAGEDDQDFNVL 1535

Query: 333  ITEKPRPQR--GLGSAARLLA------GTVAVFLILVAVLTVFFLYNRQQKSPPETDGAG 384
            I   P  Q+     +A  +L+      G V  +  +V     +   +     PP+     
Sbjct: 1536 IQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR 1595

Query: 385  TDQPLSQKPEPS 396
             DQPLS   E S
Sbjct: 1596 EDQPLSAGDEVS 1607



 Score = 32.7 bits (73), Expect = 0.70
 Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 23/250 (9%)

Query: 108  TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
            T++ + +  ED G Y+C +A    G  ++   + V   P    E    ++    G     
Sbjct: 2990 TLQRAAVSREDSGTYVC-WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS---- 3044

Query: 168  LVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226
            +   C    G P   + W +  L     +   +  NG++T+    R    R        C
Sbjct: 3045 IQLDCV-VRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGR------YQC 3097

Query: 227  IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
            +    M   K+ + L +Q  P   +E  D        DV L C+A   P  T   W  L 
Sbjct: 3098 LAENEMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDDVALRCQATGEPTPT-IEW--LQ 3153

Query: 287  GSLPKGVEAQNRTL----FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRG 342
               P     + RTL     +   +    AGTY C A N +G  S      +  +  PQ  
Sbjct: 3154 AGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLG--SATARAFLVVRGEPQGS 3211

Query: 343  LGSAARLLAG 352
             GS   ++ G
Sbjct: 3212 WGSMTGVING 3221



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 53/240 (22%), Positives = 87/240 (36%), Gaps = 23/240 (9%)

Query: 108  TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
            +++L  +   D G Y C  A    G       LTVM  P     G    L    G   ++
Sbjct: 2266 SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 2324

Query: 168  LVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACI 227
            L      A G P   ++W     G+A  +   N   T       R++  R+A   +  C+
Sbjct: 2325 LC----DAQGTPQPNITWHK--DGQALTRLENNSRAT-------RVLRVRDAGLYT--CL 2369

Query: 228  VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANP-PATEYHWT 283
                    ++S  + VQ  P +   G  G  ++  +    + L C  +A P P   +H  
Sbjct: 2370 AESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 2427

Query: 284  TLNGSLPKGVEAQNRTLFFK-GPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRG 342
             +        +   R  F +   ++ + +G Y C A N  G+ S    V I   P  + G
Sbjct: 2428 GIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSG 2487



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 61/258 (23%), Positives = 89/258 (34%), Gaps = 50/258 (19%)

Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQ---- 163
           T+ +  +EL+  G++ C+ AT   G   +++ ++V  +   W  G   VL    GQ    
Sbjct: 553 TLHIDHVELDHSGLFACQ-ATNEAGTAGAEVEVSVHGE---WAPG---VLEVPIGQYHWG 605

Query: 164 --DDKVLVATCT-------SANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYR 212
                   A C         A+ KPP V  W +   L GE        P G       Y 
Sbjct: 606 XEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGE--------PTGIPVA---YS 654

Query: 213 LVPSREAHQQSL------ACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVK 266
           L P  +  +  L       C         K  + L V   P +   G      L+   V 
Sbjct: 655 LPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE-PGPVNKAVLENASVT 713

Query: 267 LTCKADANPPATEYHWTTLNGSLPKG------VEAQNRTLFFKGPINYSLAGTYICEATN 320
           L C A   PP  +  W    G  P        V    R L  +     S AG+Y C A+N
Sbjct: 714 LECLASGVPPP-DVSW--FKGHQPVSSWMGVTVSVDGRVLRIE-QAQLSDAGSYRCVASN 769

Query: 321 PIGTRSGQVEVNITEKPR 338
             G+   +  + +   PR
Sbjct: 770 VAGSTELRYGLRVNVPPR 787



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%)

Query: 96   RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
            R   LR    +G++ + R E +D G Y C  A    G  +  + L + + P   +E    
Sbjct: 3069 RGSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 3127

Query: 156  VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185
             +R+  G D    VA    A G+P   + W
Sbjct: 3128 TVRS--GDD----VALRCQATGEPTPTIEW 3151


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 62/231 (26%), Positives = 94/231 (40%), Gaps = 17/231 (7%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            ++L R +  D GVY C+ A+   G  E    L V   PT  IEG        K    + +
Sbjct: 1558 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 1614

Query: 169  VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227
               C  A G P   +SW       AE  E R   +G+V      RL    EA     +C+
Sbjct: 1615 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 1668

Query: 228  VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
             +          ++ VQ  P++ + EG      +    ++L C+A  +P  T   W   N
Sbjct: 1669 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 1726

Query: 287  GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
            G   +   GV+ A   T      +    +G + C+ATN  GT   +VEV++
Sbjct: 1727 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 60/250 (24%), Positives = 99/250 (39%), Gaps = 19/250 (7%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            + +   ++ D+G+Y C+ +    G       LTV   PT     T+ V +         L
Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 3142

Query: 169  VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
            V TC   +G P   V+W   LK      E    +G V+   R +L   + A   +  C+ 
Sbjct: 3143 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 3197

Query: 229  NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287
                   ++   + V   P +   G     + L+  +V+L C+AD  PP  +  W     
Sbjct: 3198 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP-DVAWLKDGS 3256

Query: 288  SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQR 341
             L + +    R      +L  KG +  S AG Y C A NP G  +    VN+   P  ++
Sbjct: 3257 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 3315

Query: 342  GLGSAARLLA 351
            G   +  L++
Sbjct: 3316 GADGSGTLVS 3325



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 83/324 (25%), Positives = 119/324 (36%), Gaps = 54/324 (16%)

Query: 41   GFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFL 100
            G  G DV L C  +     V   QV W K     +Q V    P + V             
Sbjct: 1420 GLAGADVELQCWTSG----VPTPQVEWTKD----RQPVLPGGPHLQVQ------------ 1459

Query: 101  RPSFTDGTI-RLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA 159
                 DG + R++   + DEG Y C  A  P G +     L V A PT W  G+      
Sbjct: 1460 ----EDGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIW--GSNETGEV 1512

Query: 160  KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISR----YRLVP 215
               +D   LV     A G P   ++W    K  A       P  T  V +R     +L  
Sbjct: 1513 AVMEDH--LVQLLCEARGVPTPNITW---FKDGALL-----PTSTKVVYTRGGRQLQLGR 1562

Query: 216  SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM----DVKLTCKA 271
            ++ +      C  +  +   +++  L+V   P  TIEG  G  Y+ +      V L C A
Sbjct: 1563 AQSSDAGVYTCKASNAVGAAEKATRLDVYVPP--TIEGAGGRPYVVKAVAGRPVALECVA 1620

Query: 272  DANP-PATEYHWTTLN--GSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328
              +P P   +H   L    S    +E     L  + P   S +G Y C A++P G    Q
Sbjct: 1621 RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEAS-SGLYSCVASSPAGEAVLQ 1679

Query: 329  --VEVNITEKPRPQRGLGSAARLL 350
              VEV +  +     GLG    ++
Sbjct: 1680 YSVEVQVPPQLLVAEGLGQVTTIV 1703



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 60/238 (25%), Positives = 92/238 (38%), Gaps = 25/238 (10%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            +++ +++L DEG+Y C  AT   G  + ++ L V+  P N   G        K   +   
Sbjct: 1850 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 1902

Query: 169  VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226
            V     A+G PP  VSW    KG   +Q + +  G TV+V  R  R+  ++ +   S  C
Sbjct: 1903 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 1956

Query: 227  IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
            + +      +    L V   P +T+        L    V+LTC A   P  T       N
Sbjct: 1957 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 2016

Query: 287  GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIGTRSGQVEVNITEKP 337
               P G         F G    +LA       G Y C A + +G     V + +   P
Sbjct: 2017 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPP 2071



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 54/220 (24%), Positives = 87/220 (39%), Gaps = 45/220 (20%)

Query: 151 EGTQ---AVLRAKKGQDDKVLVAT--------CTSANGKPPSVVSWETRLKGEAEYQEIR 199
           EGT    AV RA  G+    +V T          +    P        R+ GEA Y    
Sbjct: 491 EGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYN--- 547

Query: 200 NPNGTVTVISRYRLVPSREAHQQSLA------------------CIVNYHMDRFKESLTL 241
                +T +  +R++P+       LA                  C+ +      + S+ L
Sbjct: 548 -----LTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWL 602

Query: 242 NVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG----VEAQN 297
            V+  P+V+I       + Q ++VK++C A   P      W+  + +L +     V+AQ 
Sbjct: 603 LVREAPQVSIHT-SSQHFSQGVEVKVSCSASGYP-TPHISWSRESQALQEDSRIHVDAQG 660

Query: 298 RTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
            TL  +G +    AG Y C+ATN +GT    V +  T+ P
Sbjct: 661 -TLIIQG-VAPEDAGNYSCQATNEVGTDQETVTLYYTDPP 698



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/243 (21%), Positives = 90/243 (37%), Gaps = 36/243 (14%)

Query: 107  GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158
            G +R++    ED G Y+C  A    G+   +  L V   P         +  EG+ A L 
Sbjct: 4000 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 4058

Query: 159  AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218
             K              A G P   ++W+       + Q +    G  T+     L+    
Sbjct: 4059 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 4098

Query: 219  AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
              Q +    C     + R +  + L +   P  T     G+  L+  D + L C A  +P
Sbjct: 4099 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 4156

Query: 276  PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
                  WT  +  + +GV  Q+  +   +  ++   +GTY+C A N +G       V++ 
Sbjct: 4157 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 4215

Query: 335  EKP 337
            E P
Sbjct: 4216 EAP 4218



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 54/238 (22%), Positives = 98/238 (41%), Gaps = 27/238 (11%)

Query: 107  GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDK 166
            G++RL+++++ D G Y C  A+ P G+   +  L V   P   ++    VL+   G+   
Sbjct: 1082 GSLRLAQVQVGDSGHYECT-ASNPAGSASHRYVLGVQVPPQ--VQPGPRVLKVLVGE--- 1135

Query: 167  VLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226
             L   C  A G P   +SW      +    + R P G+V     +  + + +A +     
Sbjct: 1136 ALDLNCV-AEGNPEPQLSWSK----DGVVLQGRGPQGSV----HFAAIRTSDAGRYRCEA 1186

Query: 227  IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANPPATEYHWT 283
              +  +D ++  + L V   P    +   G   L+R+   +  L C A   P   +  W 
Sbjct: 1187 SNSAGVDAWE--VELRVLEPPHWGADETSG--LLERVAGENASLPCPARGTPKP-QVTWR 1241

Query: 284  TLNGSLP----KGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
                S P     GV        F   ++ + +G Y C+ATN +G+ S + ++ +   P
Sbjct: 1242 KGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPP 1299



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 56/238 (23%), Positives = 83/238 (34%), Gaps = 26/238 (10%)

Query: 111  LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170
            L + +L  EG Y CE +    GN    L L V   P   I G +          D V   
Sbjct: 2222 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 2278

Query: 171  TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
             C +A GKPP  V+WE   +  G     +++N   ++ V        ++ AH    +C+ 
Sbjct: 2279 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 2331

Query: 229  NYHMDRFKESLTLNVQYEPEV--TIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
                 R +    L+V   PE+   ++            + L C+A   PP     W    
Sbjct: 2332 ENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPA-IRW--FR 2388

Query: 287  GSLPKGVEAQNRTLFFKGPINYSL-------AGTYICEATNPIGTRSGQVEVNITEKP 337
            G  P  V     T    G     +       +G Y C A+N  G       V +   P
Sbjct: 2389 GEEP--VSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPP 2444



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 72/314 (22%), Positives = 109/314 (34%), Gaps = 53/314 (16%)

Query: 37   DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95
            + +   + + V L C   A+P P     +VTW K +            S+G  V      
Sbjct: 2945 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 2984

Query: 96   RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
               FL P     T++L R  L D G+Y CE A    G  +  + L+V+  P        A
Sbjct: 2985 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 3030

Query: 156  VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
              +A +G  D VLV     A      +  P   V+W    +     Q  +   G      
Sbjct: 3031 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 3086

Query: 210  RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
            R  +  ++ + +   +C V+        + TL VQ  P       +    +    + LTC
Sbjct: 3087 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 3146

Query: 270  KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATNPIGT 324
                 P  T    T L   +P    A +  +   G +  S      AGTY C A N    
Sbjct: 3147 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAE 3203

Query: 325  RSGQVEVNITEKPR 338
                  V +   PR
Sbjct: 3204 ARKDFVVAVLVAPR 3217



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 58/248 (23%), Positives = 88/248 (35%), Gaps = 30/248 (12%)

Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164
           + G +R+   +  D G Y C  A    G+  +++ L V   P         + R    + 
Sbjct: 746 SSGKLRIPAAQERDAGTYTCR-AVNELGDASAEIQLAVGHAPQ-----LTELPRDVTVEL 799

Query: 165 DKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSL 224
            +  +  C  A G+PP  V+W    +G+ +   +R   G     SR R   S     +S+
Sbjct: 800 GRSALLACR-ATGRPPPTVTWR---RGDGQPLGLRLGAGRG---SRSRQPDSGVLFFESV 852

Query: 225 A--------CIVNYHMDRFKESLTLNVQ-YEPEVTIEGFDGNWYLQRMDVKLTCKADANP 275
           A        C       + +    L V  + P            L+   V L C   A  
Sbjct: 853 APEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGR 912

Query: 276 PATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYICEATNPIGTRSGQVE 330
           P  E HW      LP G     R     G ++   A     G Y C ATN  G++   VE
Sbjct: 913 PLPERHWLKDGRPLPPGSRHSIRA---DGSLHLDRALQEHAGRYSCVATNTAGSQHRDVE 969

Query: 331 VNITEKPR 338
           + +   PR
Sbjct: 970 LVVQVPPR 977



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 59/247 (23%), Positives = 90/247 (36%), Gaps = 27/247 (10%)

Query: 100  LRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--NWIEGTQAVL 157
            LR     G++ L  L   D G Y C  A  P G       + V+  PT     +G+   L
Sbjct: 3266 LRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGS-GTL 3323

Query: 158  RAKKGQDDKVLVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPS 216
             ++ G+    LV       G PP  VSW +  L      + + + +G    IS+ +L   
Sbjct: 3324 VSRPGE----LVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQL--- 3376

Query: 217  REAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
              A      C+          + TL VQ  P +    F  +  + R   V+L C+A    
Sbjct: 3377 --ADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEA-RGV 3433

Query: 276  PATEYHWTT-----LNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVE 330
            P     W       L+ SL +G   Q         +    +GTY C A +  G      +
Sbjct: 3434 PLPLVSWMKDGEPLLSQSLEQGPSLQLEA------VGAGDSGTYSCVAVSEAGEARRHFQ 3487

Query: 331  VNITEKP 337
            + + E P
Sbjct: 3488 LTVMEPP 3494



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 74/336 (22%), Positives = 115/336 (34%), Gaps = 52/336 (15%)

Query: 20   LTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTN--GSKQN 77
            L  +  P +     + N S  G  G  + L C  AN  P   + ++ W K     G    
Sbjct: 1293 LVVYVPPSIREDGRKANVS--GMAGQSLTLECD-ANGFP---VPEIVWLKDAQLVGVPLG 1346

Query: 78   VAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQ 137
             A Y   +G   +  +R   E         ++   R++  D G+Y C  A    G  +  
Sbjct: 1347 WAGYGWDLGWGQVGGHRLLDE-------GQSLHFPRIQEGDSGLYSCR-AENQAGTAQRD 1398

Query: 138  LNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWET---------- 187
             +L V+  P+    G    +    G D ++   T    +G P   V W            
Sbjct: 1399 FHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWT----SGVPTPQVEWTKDRQPVLPGGP 1454

Query: 188  RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEP 247
             L+ + + Q +R     V    RY+ V    A QQ+                 L V   P
Sbjct: 1455 HLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQA-------------RDFQLRVHAPP 1501

Query: 248  EVTIEGFDGNWYLQRMD---VKLTCKADANPPATEYHWTTLNGSLP---KGVEAQNRTLF 301
              TI G +    +  M+   V+L C+A    P     W      LP   K V  +     
Sbjct: 1502 --TIWGSNETGEVAVMEDHLVQLLCEA-RGVPTPNITWFKDGALLPTSTKVVYTRGGRQL 1558

Query: 302  FKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
              G    S AG Y C+A+N +G       +++   P
Sbjct: 1559 QLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPP 1594



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 53/236 (22%), Positives = 84/236 (35%), Gaps = 21/236 (8%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            +R+ + +L D G Y C  A+   G+ E +  L V   P          +         VL
Sbjct: 1941 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 1990

Query: 169  VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223
            V T      +A G P   + W   LK          P   V    R   L  +R +    
Sbjct: 1991 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 2047

Query: 224  LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
             +C+    +   ++ + L V   P +  E  + +  +    V L C++ A PP     W 
Sbjct: 2048 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 2106

Query: 284  TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
                  P+ GV  + ++ L      +   AG Y CEA N  G       +N+   P
Sbjct: 2107 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAP 2162



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 54/261 (20%), Positives = 86/261 (32%), Gaps = 38/261 (14%)

Query: 90   LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149
            L P   R E L     +G++R+  +  +D G Y+C  A+   G+     +L V+  P   
Sbjct: 3713 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 3767

Query: 150  IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
               +   L A         +  C ++    P VV W+   K +   Q+            
Sbjct: 3768 PSPSNLTLTAHTPA-----LLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 3811

Query: 210  RYRLVPSREA--------HQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261
             YRL+PS                 C+V+  +        + V   P +  +  D    + 
Sbjct: 3812 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 3871

Query: 262  RMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYIC 316
               V LTC +   P  T   W+     L  G       +   G +    A     G Y C
Sbjct: 3872 A-PVVLTCHSTGIPAPT-VSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTC 3927

Query: 317  EATNPIGTRSGQVEVNITEKP 337
             A N  G     V + +   P
Sbjct: 3928 SARNSAGVAHKHVFLTVQASP 3948



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 63/312 (20%), Positives = 114/312 (36%), Gaps = 38/312 (12%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            +++ +  L   G Y C  A    G +     L+V+  PT        +L   +   D+ +
Sbjct: 2501 LQVLQANLSSAGHYSC-IAANAVGEKTKHFQLSVLLAPT--------ILGGAEDSADEEV 2551

Query: 169  VATCTS-------ANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQ 221
              T  +       A   P   ++W   +K  A ++  RN    +      +++ +++   
Sbjct: 2552 TVTVNNPISLICEALAFPSPNITW---MKDGAPFEASRNIQ-LLPGTHGLQILNAQKEDA 2607

Query: 222  QSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVK------LTCKADANP 275
                C+V   +    ++  + V   P ++ +   G   ++ +  K      L C++ A P
Sbjct: 2608 GQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVP 2667

Query: 276  PATEYHWTTLNGSLPKG---VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332
            P T   +       P     V  + R L  + P   S +G Y+C ATN  G       V 
Sbjct: 2668 PPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQ-PTQVSDSGRYLCVATNVAGEDDQDFNVL 2726

Query: 333  ITEKPRPQR--GLGSAARLLA------GTVAVFLILVAVLTVFFLYNRQQKSPPETDGAG 384
            I   P  Q+     +A  +L+      G V  +  +V     +   +     PP+     
Sbjct: 2727 IQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR 2786

Query: 385  TDQPLSQKPEPS 396
             DQPLS   E S
Sbjct: 2787 EDQPLSAGDEVS 2798



 Score = 32.7 bits (73), Expect = 0.70
 Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 23/250 (9%)

Query: 108  TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
            T++ + +  ED G Y+C +A    G  ++   + V   P    E    ++    G     
Sbjct: 4181 TLQRAAVSREDSGTYVC-WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS---- 4235

Query: 168  LVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226
            +   C    G P   + W +  L     +   +  NG++T+    R    R        C
Sbjct: 4236 IQLDCV-VRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGR------YQC 4288

Query: 227  IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
            +    M   K+ + L +Q  P   +E  D        DV L C+A   P  T   W  L 
Sbjct: 4289 LAENEMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDDVALRCQATGEPTPT-IEW--LQ 4344

Query: 287  GSLPKGVEAQNRTL----FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRG 342
               P     + RTL     +   +    AGTY C A N +G  S      +  +  PQ  
Sbjct: 4345 AGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLG--SATARAFLVVRGEPQGS 4402

Query: 343  LGSAARLLAG 352
             GS   ++ G
Sbjct: 4403 WGSMTGVING 4412



 Score = 32.3 bits (72), Expect = 0.92
 Identities = 53/241 (21%), Positives = 87/241 (36%), Gaps = 36/241 (14%)

Query: 107  GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDK 166
            G +    +  ED+  Y+CE A    G  +++  L V       I  +   +R  +GQ   
Sbjct: 845  GVLFFESVAPEDQAPYVCE-ARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVS 903

Query: 167  VLVATCTSANGKPPSVVSW--ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSL 224
            +    C    G+P     W  + R         IR  +G++       L  + + H    
Sbjct: 904  L---PCIVLAGRPLPERHWLKDGRPLPPGSRHSIR-ADGSL------HLDRALQEHAGRY 953

Query: 225  ACIVNYHMDRFKESLTLNVQYEPEV--------TIEGFDGNWYLQRMDVKLTCKADANPP 276
            +C+           + L VQ  P +        T EG         +   L C A +  P
Sbjct: 954  SCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEG---------VPASLPCVA-SGVP 1003

Query: 277  ATEYHWTTLNGSL----PKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332
            A    WT    +L    P    ++  TL    P     AG Y+C ATN +G  S ++ ++
Sbjct: 1004 APTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQD-AGAYVCTATNTVGFSSQEMRLS 1062

Query: 333  I 333
            +
Sbjct: 1063 V 1063



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 53/240 (22%), Positives = 87/240 (36%), Gaps = 23/240 (9%)

Query: 108  TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
            +++L  +   D G Y C  A    G       LTVM  P     G    L    G   ++
Sbjct: 3457 SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 3515

Query: 168  LVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACI 227
            L      A G P   ++W     G+A  +   N   T       R++  R+A   +  C+
Sbjct: 3516 LC----DAQGTPQPNITWHK--DGQALTRLENNSRAT-------RVLRVRDAGLYT--CL 3560

Query: 228  VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANP-PATEYHWT 283
                    ++S  + VQ  P +   G  G  ++  +    + L C  +A P P   +H  
Sbjct: 3561 AESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 3618

Query: 284  TLNGSLPKGVEAQNRTLFFK-GPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRG 342
             +        +   R  F +   ++ + +G Y C A N  G+ S    V I   P  + G
Sbjct: 3619 GIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSG 3678



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 61/258 (23%), Positives = 89/258 (34%), Gaps = 50/258 (19%)

Query: 108  TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQ---- 163
            T+ +  +EL+  G++ C+ AT   G   +++ ++V  +   W  G   VL    GQ    
Sbjct: 1744 TLHIDHVELDHSGLFACQ-ATNEAGTAGAEVEVSVHGE---WAPG---VLEVPIGQYHWG 1796

Query: 164  --DDKVLVATCT-------SANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYR 212
                    A C         A+ KPP V  W +   L GE        P G       Y 
Sbjct: 1797 XEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGE--------PTGIPVA---YS 1845

Query: 213  LVPSREAHQQSL------ACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVK 266
            L P  +  +  L       C         K  + L V   P +   G      L+   V 
Sbjct: 1846 LPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE-PGPVNKAVLENASVT 1904

Query: 267  LTCKADANPPATEYHWTTLNGSLPKG------VEAQNRTLFFKGPINYSLAGTYICEATN 320
            L C A   PP  +  W    G  P        V    R L  +     S AG+Y C A+N
Sbjct: 1905 LECLASGVPPP-DVSW--FKGHQPVSSWMGVTVSVDGRVLRIE-QAQLSDAGSYRCVASN 1960

Query: 321  PIGTRSGQVEVNITEKPR 338
              G+   +  + +   PR
Sbjct: 1961 VAGSTELRYGLRVNVPPR 1978



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%)

Query: 96   RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
            R   LR    +G++ + R E +D G Y C  A    G  +  + L + + P   +E    
Sbjct: 4260 RGSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 4318

Query: 156  VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185
             +R+  G D    VA    A G+P   + W
Sbjct: 4319 TVRS--GDD----VALRCQATGEPTPTIEW 4342


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 62/231 (26%), Positives = 94/231 (40%), Gaps = 17/231 (7%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           ++L R +  D GVY C+ A+   G  E    L V   PT  IEG        K    + +
Sbjct: 276 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 332

Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227
              C  A G P   +SW       AE  E R   +G+V      RL    EA     +C+
Sbjct: 333 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 386

Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
            +          ++ VQ  P++ + EG      +    ++L C+A  +P  T   W   N
Sbjct: 387 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 444

Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
           G   +   GV+ A   T      +    +G + C+ATN  GT   +VEV++
Sbjct: 445 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 495



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 60/250 (24%), Positives = 99/250 (39%), Gaps = 19/250 (7%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            + +   ++ D+G+Y C+ +    G       LTV   PT     T+ V +         L
Sbjct: 1806 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 1860

Query: 169  VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
            V TC   +G P   V+W   LK      E    +G V+   R +L   + A   +  C+ 
Sbjct: 1861 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 1915

Query: 229  NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287
                   ++   + V   P +   G     + L+  +V+L C+AD  PP  +  W     
Sbjct: 1916 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP-DVAWLKDGS 1974

Query: 288  SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQR 341
             L + +    R      +L  KG +  S AG Y C A NP G  +    VN+   P  ++
Sbjct: 1975 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 2033

Query: 342  GLGSAARLLA 351
            G   +  L++
Sbjct: 2034 GADGSGTLVS 2043



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 83/324 (25%), Positives = 119/324 (36%), Gaps = 54/324 (16%)

Query: 41  GFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFL 100
           G  G DV L C  +     V   QV W K     +Q V    P + V             
Sbjct: 138 GLAGADVELQCWTSG----VPTPQVEWTKD----RQPVLPGGPHLQVQ------------ 177

Query: 101 RPSFTDGTI-RLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA 159
                DG + R++   + DEG Y C  A  P G +     L V A PT W  G+      
Sbjct: 178 ----EDGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIW--GSNETGEV 230

Query: 160 KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISR----YRLVP 215
              +D   LV     A G P   ++W    K  A       P  T  V +R     +L  
Sbjct: 231 AVMEDH--LVQLLCEARGVPTPNITW---FKDGALL-----PTSTKVVYTRGGRQLQLGR 280

Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM----DVKLTCKA 271
           ++ +      C  +  +   +++  L+V   P  TIEG  G  Y+ +      V L C A
Sbjct: 281 AQSSDAGVYTCKASNAVGAAEKATRLDVYVPP--TIEGAGGRPYVVKAVAGRPVALECVA 338

Query: 272 DANP-PATEYHWTTLN--GSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328
             +P P   +H   L    S    +E     L  + P   S +G Y C A++P G    Q
Sbjct: 339 RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEAS-SGLYSCVASSPAGEAVLQ 397

Query: 329 --VEVNITEKPRPQRGLGSAARLL 350
             VEV +  +     GLG    ++
Sbjct: 398 YSVEVQVPPQLLVAEGLGQVTTIV 421



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 60/238 (25%), Positives = 92/238 (38%), Gaps = 25/238 (10%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           +++ +++L DEG+Y C  AT   G  + ++ L V+  P N   G        K   +   
Sbjct: 568 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 620

Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226
           V     A+G PP  VSW    KG   +Q + +  G TV+V  R  R+  ++ +   S  C
Sbjct: 621 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 674

Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
           + +      +    L V   P +T+        L    V+LTC A   P  T       N
Sbjct: 675 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 734

Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIGTRSGQVEVNITEKP 337
              P G         F G    +LA       G Y C A + +G     V + +   P
Sbjct: 735 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPP 789



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/243 (21%), Positives = 90/243 (37%), Gaps = 36/243 (14%)

Query: 107  GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158
            G +R++    ED G Y+C  A    G+   +  L V   P         +  EG+ A L 
Sbjct: 2718 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2776

Query: 159  AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218
             K              A G P   ++W+       + Q +    G  T+     L+    
Sbjct: 2777 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 2816

Query: 219  AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
              Q +    C     + R +  + L +   P  T     G+  L+  D + L C A  +P
Sbjct: 2817 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 2874

Query: 276  PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
                  WT  +  + +GV  Q+  +   +  ++   +GTY+C A N +G       V++ 
Sbjct: 2875 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 2933

Query: 335  EKP 337
            E P
Sbjct: 2934 EAP 2936



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 56/238 (23%), Positives = 83/238 (34%), Gaps = 26/238 (10%)

Query: 111  LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170
            L + +L  EG Y CE +    GN    L L V   P   I G +          D V   
Sbjct: 940  LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 996

Query: 171  TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
             C +A GKPP  V+WE   +  G     +++N   ++ V        ++ AH    +C+ 
Sbjct: 997  EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 1049

Query: 229  NYHMDRFKESLTLNVQYEPEV--TIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
                 R +    L+V   PE+   ++            + L C+A   PP     W    
Sbjct: 1050 ENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPA-IRW--FR 1106

Query: 287  GSLPKGVEAQNRTLFFKGPINYSL-------AGTYICEATNPIGTRSGQVEVNITEKP 337
            G  P  V     T    G     +       +G Y C A+N  G       V +   P
Sbjct: 1107 GEEP--VSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPP 1162



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 72/314 (22%), Positives = 109/314 (34%), Gaps = 53/314 (16%)

Query: 37   DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95
            + +   + + V L C   A+P P     +VTW K +            S+G  V      
Sbjct: 1663 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 1702

Query: 96   RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
               FL P     T++L R  L D G+Y CE A    G  +  + L+V+  P        A
Sbjct: 1703 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 1748

Query: 156  VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
              +A +G  D VLV     A      +  P   V+W    +     Q  +   G      
Sbjct: 1749 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 1804

Query: 210  RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
            R  +  ++ + +   +C V+        + TL VQ  P       +    +    + LTC
Sbjct: 1805 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1864

Query: 270  KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATNPIGT 324
                 P  T    T L   +P    A +  +   G +  S      AGTY C A N    
Sbjct: 1865 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAE 1921

Query: 325  RSGQVEVNITEKPR 338
                  V +   PR
Sbjct: 1922 ARKDFVVAVLVAPR 1935



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 59/247 (23%), Positives = 90/247 (36%), Gaps = 27/247 (10%)

Query: 100  LRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--NWIEGTQAVL 157
            LR     G++ L  L   D G Y C  A  P G       + V+  PT     +G+   L
Sbjct: 1984 LRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGS-GTL 2041

Query: 158  RAKKGQDDKVLVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPS 216
             ++ G+    LV       G PP  VSW +  L      + + + +G    IS+ +L   
Sbjct: 2042 VSRPGE----LVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQL--- 2094

Query: 217  REAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
              A      C+          + TL VQ  P +    F  +  + R   V+L C+A    
Sbjct: 2095 --ADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEA-RGV 2151

Query: 276  PATEYHWTT-----LNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVE 330
            P     W       L+ SL +G   Q         +    +GTY C A +  G      +
Sbjct: 2152 PLPLVSWMKDGEPLLSQSLEQGPSLQLEA------VGAGDSGTYSCVAVSEAGEARRHFQ 2205

Query: 331  VNITEKP 337
            + + E P
Sbjct: 2206 LTVMEPP 2212



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 70/315 (22%), Positives = 108/315 (34%), Gaps = 50/315 (15%)

Query: 41  GFIGTDVVLHCSFANPLPSVKITQVTWQKSTN--GSKQNVAIYNPSMGVSVLAPYRERVE 98
           G  G  + L C  AN  P   + ++ W K     G     A Y   +G   +  +R   E
Sbjct: 30  GMAGQSLTLECD-ANGFP---VPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDE 85

Query: 99  FLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLR 158
                    ++   R++  D G+Y C  A    G  +   +L V+  P+    G    + 
Sbjct: 86  -------GQSLHFPRIQEGDSGLYSCR-AENQAGTAQRDFHLLVLTPPSVLGAGAAQEVL 137

Query: 159 AKKGQDDKVLVATCTSANGKPPSVVSWET----------RLKGEAEYQEIRNPNGTVTVI 208
              G D ++   T    +G P   V W             L+ + + Q +R     V   
Sbjct: 138 GLAGADVELQCWT----SGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE 193

Query: 209 SRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD---V 265
            RY+ V    A QQ+                 L V   P  TI G +    +  M+   V
Sbjct: 194 GRYQCVAFSPAGQQA-------------RDFQLRVHAPP--TIWGSNETGEVAVMEDHLV 238

Query: 266 KLTCKADANPPATEYHWTTLNGSLP---KGVEAQNRTLFFKGPINYSLAGTYICEATNPI 322
           +L C+A    P     W      LP   K V  +       G    S AG Y C+A+N +
Sbjct: 239 QLLCEA-RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAV 297

Query: 323 GTRSGQVEVNITEKP 337
           G       +++   P
Sbjct: 298 GAAEKATRLDVYVPP 312



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 53/236 (22%), Positives = 84/236 (35%), Gaps = 21/236 (8%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           +R+ + +L D G Y C  A+   G+ E +  L V   P          +         VL
Sbjct: 659 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 708

Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223
           V T      +A G P   + W   LK          P   V    R   L  +R +    
Sbjct: 709 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 765

Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
            +C+    +   ++ + L V   P +  E  + +  +    V L C++ A PP     W 
Sbjct: 766 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 824

Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
                 P+ GV  + ++ L      +   AG Y CEA N  G       +N+   P
Sbjct: 825 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAP 880



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 54/261 (20%), Positives = 86/261 (32%), Gaps = 38/261 (14%)

Query: 90   LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149
            L P   R E L     +G++R+  +  +D G Y+C  A+   G+     +L V+  P   
Sbjct: 2431 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 2485

Query: 150  IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
               +   L A         +  C ++    P VV W+   K +   Q+            
Sbjct: 2486 PSPSNLTLTAHTPA-----LLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 2529

Query: 210  RYRLVPSREA--------HQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261
             YRL+PS                 C+V+  +        + V   P +  +  D    + 
Sbjct: 2530 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 2589

Query: 262  RMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYIC 316
               V LTC +   P  T   W+     L  G       +   G +    A     G Y C
Sbjct: 2590 A-PVVLTCHSTGIPAPT-VSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTC 2645

Query: 317  EATNPIGTRSGQVEVNITEKP 337
             A N  G     V + +   P
Sbjct: 2646 SARNSAGVAHKHVFLTVQASP 2666



 Score = 32.7 bits (73), Expect = 0.70
 Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 23/250 (9%)

Query: 108  TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
            T++ + +  ED G Y+C +A    G  ++   + V   P    E    ++    G     
Sbjct: 2899 TLQRAAVSREDSGTYVC-WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS---- 2953

Query: 168  LVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226
            +   C    G P   + W +  L     +   +  NG++T+    R    R        C
Sbjct: 2954 IQLDCV-VRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGR------YQC 3006

Query: 227  IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
            +    M   K+ + L +Q  P   +E  D        DV L C+A   P  T   W  L 
Sbjct: 3007 LAENEMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDDVALRCQATGEPTPT-IEW--LQ 3062

Query: 287  GSLPKGVEAQNRTL----FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRG 342
               P     + RTL     +   +    AGTY C A N +G  S      +  +  PQ  
Sbjct: 3063 AGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLG--SATARAFLVVRGEPQGS 3120

Query: 343  LGSAARLLAG 352
             GS   ++ G
Sbjct: 3121 WGSMTGVING 3130



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 53/240 (22%), Positives = 87/240 (36%), Gaps = 23/240 (9%)

Query: 108  TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
            +++L  +   D G Y C  A    G       LTVM  P     G    L    G   ++
Sbjct: 2175 SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 2233

Query: 168  LVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACI 227
            L      A G P   ++W     G+A  +   N   T       R++  R+A   +  C+
Sbjct: 2234 LC----DAQGTPQPNITWHK--DGQALTRLENNSRAT-------RVLRVRDAGLYT--CL 2278

Query: 228  VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANP-PATEYHWT 283
                    ++S  + VQ  P +   G  G  ++  +    + L C  +A P P   +H  
Sbjct: 2279 AESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 2336

Query: 284  TLNGSLPKGVEAQNRTLFFK-GPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRG 342
             +        +   R  F +   ++ + +G Y C A N  G+ S    V I   P  + G
Sbjct: 2337 GIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSG 2396



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 61/258 (23%), Positives = 89/258 (34%), Gaps = 50/258 (19%)

Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQ---- 163
           T+ +  +EL+  G++ C+ AT   G   +++ ++V  +   W  G   VL    GQ    
Sbjct: 462 TLHIDHVELDHSGLFACQ-ATNEAGTAGAEVEVSVHGE---WAPG---VLEVPIGQYHWG 514

Query: 164 --DDKVLVATCT-------SANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYR 212
                   A C         A+ KPP V  W +   L GE        P G       Y 
Sbjct: 515 XEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGE--------PTGIPVA---YS 563

Query: 213 LVPSREAHQQSL------ACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVK 266
           L P  +  +  L       C         K  + L V   P +   G      L+   V 
Sbjct: 564 LPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE-PGPVNKAVLENASVT 622

Query: 267 LTCKADANPPATEYHWTTLNGSLPKG------VEAQNRTLFFKGPINYSLAGTYICEATN 320
           L C A   PP  +  W    G  P        V    R L  +     S AG+Y C A+N
Sbjct: 623 LECLASGVPPP-DVSW--FKGHQPVSSWMGVTVSVDGRVLRIE-QAQLSDAGSYRCVASN 678

Query: 321 PIGTRSGQVEVNITEKPR 338
             G+   +  + +   PR
Sbjct: 679 VAGSTELRYGLRVNVPPR 696



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 62/312 (19%), Positives = 113/312 (36%), Gaps = 38/312 (12%)

Query: 109  IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
            +++ +  L   G Y C  A    G +     L+V+  PT        +L   +   D+ +
Sbjct: 1219 LQVLQANLSSAGHYSC-IAANAVGEKTKHFQLSVLLAPT--------ILGGAEDSADEEV 1269

Query: 169  VATCTS-------ANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQ 221
              T  +       A   P   ++W   +K  A ++  RN    +      +++ +++   
Sbjct: 1270 TVTVNNPISLICEALAFPSPNITW---MKDGAPFEASRNIQ-LLPGTHGLQILNAQKEDA 1325

Query: 222  QSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVK------LTCKADANP 275
                C+V   +    ++  + V   P ++ +       ++ +  K      L C++ A P
Sbjct: 1326 GQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVP 1385

Query: 276  PATEYHWTTLNGSLPKG---VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332
            P T   +       P     V  + R L  + P   S +G Y+C ATN  G       V 
Sbjct: 1386 PPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQ-PTQVSDSGRYLCVATNVAGEDDQDFNVL 1444

Query: 333  ITEKPRPQR--GLGSAARLLA------GTVAVFLILVAVLTVFFLYNRQQKSPPETDGAG 384
            I   P  Q+     +A  +L+      G V  +  +V     +   +     PP+     
Sbjct: 1445 IQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR 1504

Query: 385  TDQPLSQKPEPS 396
             DQPLS   E S
Sbjct: 1505 EDQPLSAGDEVS 1516



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%)

Query: 96   RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
            R   LR    +G++ + R E +D G Y C  A    G  +  + L + + P   +E    
Sbjct: 2978 RGSHLRHQLQNGSLTIRRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 3036

Query: 156  VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185
             +R+  G D    VA    A G+P   + W
Sbjct: 3037 TVRS--GDD----VALRCQATGEPTPTIEW 3060


>gi|166295173 kin of IRRE like [Homo sapiens]
          Length = 757

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 55/239 (23%), Positives = 98/239 (41%), Gaps = 23/239 (9%)

Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
           + ++  EL D+  Y C+       +R ++L + +  + T    G   +L+A    +    
Sbjct: 85  LEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHN---- 140

Query: 169 VATCTSANGKPPSVVSW---ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225
             TC + N KP + + W    T+ +G     E+       T +S+  + P+     +   
Sbjct: 141 -LTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFT 199

Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
           C  +N  +   KE S+ L+V + P VT+   +     +   V  TC+A ANP    Y W 
Sbjct: 200 CRSMNEAIPSGKETSIELDVHHPPTVTLS-IEPQTVQEGERVVFTCQATANPEILGYRWA 258

Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKPR 338
                +    E++  T     FF  P++        CE  N +G+ +    VN+   PR
Sbjct: 259 KGGFLIEDAHESRYETNVDYSFFTEPVS--------CEVHNKVGSTNVSTLVNVHFAPR 309



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 7/130 (5%)

Query: 209 SRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLT 268
           SRY          + ++C V+  +     S  +NV + P + ++       +   DV LT
Sbjct: 270 SRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGS-DVTLT 328

Query: 269 CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNP-IGTRSG 327
           C    NPP T   WT  + ++   V + +  L  K  +  + AGTY C A  P IG    
Sbjct: 329 CVWVGNPPLT-LTWTKKDSNM---VLSNSNQLLLKS-VTQADAGTYTCRAIVPRIGVAER 383

Query: 328 QVEVNITEKP 337
           +V + +   P
Sbjct: 384 EVPLYVNGPP 393


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,282,407
Number of Sequences: 37866
Number of extensions: 942536
Number of successful extensions: 4796
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 258
Number of HSP's that attempted gapping in prelim test: 3772
Number of HSP's gapped (non-prelim): 1054
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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