BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens] (518 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens] 1071 0.0 gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] 1006 0.0 gi|14249412 tripartite motif-containing 52 [Homo sapiens] 344 1e-94 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 227 2e-59 gi|21630277 tripartite motif-containing 11 [Homo sapiens] 215 9e-56 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 214 1e-55 gi|5730009 ret finger protein [Homo sapiens] 214 2e-55 gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 202 6e-52 gi|15208660 tripartite motif protein 21 [Homo sapiens] 190 3e-48 gi|37622899 ring finger protein 137 [Homo sapiens] 186 3e-47 gi|112421127 tripartite motif-containing 58 [Homo sapiens] 180 2e-45 gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] 177 2e-44 gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 177 2e-44 gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 177 2e-44 gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 176 5e-44 gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 176 5e-44 gi|22749269 ring finger protein 129 [Homo sapiens] 176 6e-44 gi|157743261 tripartite motif-containing 75 [Homo sapiens] 168 1e-41 gi|5454014 tripartite motif-containing 38 [Homo sapiens] 158 1e-38 gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapi... 156 4e-38 gi|149193331 tripartite motif protein 15 [Homo sapiens] 154 1e-37 gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 152 7e-37 gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 152 7e-37 gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 149 5e-36 gi|4508005 tripartite motif-containing 26 [Homo sapiens] 141 1e-33 gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 137 2e-32 gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 133 3e-31 gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 128 1e-29 gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 128 1e-29 gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 128 1e-29 >gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens] Length = 518 Score = 1072 bits (2771), Expect = 0.0 Identities = 518/518 (100%), Positives = 518/518 (100%) Query: 1 MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60 MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD Sbjct: 1 MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60 Query: 61 REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120 REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM Sbjct: 61 REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120 Query: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC Sbjct: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180 Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV Sbjct: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT Sbjct: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL Sbjct: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK Sbjct: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG Sbjct: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480 Query: 481 FRSGRHYWEEPKEPSWPPAQPSLTYYVCPTDRPEFSFT 518 FRSGRHYWEEPKEPSWPPAQPSLTYYVCPTDRPEFSFT Sbjct: 481 FRSGRHYWEEPKEPSWPPAQPSLTYYVCPTDRPEFSFT 518 >gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] Length = 630 Score = 1006 bits (2601), Expect = 0.0 Identities = 489/489 (100%), Positives = 489/489 (100%) Query: 1 MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60 MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD Sbjct: 1 MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60 Query: 61 REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120 REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM Sbjct: 61 REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNM 120 Query: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC Sbjct: 121 DYVWEEEDEEEDLDYYLGDMEEEDLRGEDEEDEEEVLEEVEEEDLDPVTPLPPPPAPRRC 180 Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV Sbjct: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT Sbjct: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL Sbjct: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK Sbjct: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG Sbjct: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480 Query: 481 FRSGRHYWE 489 FRSGRHYWE Sbjct: 481 FRSGRHYWE 489 >gi|14249412 tripartite motif-containing 52 [Homo sapiens] Length = 297 Score = 344 bits (883), Expect = 1e-94 Identities = 178/277 (64%), Positives = 213/277 (76%), Gaps = 12/277 (4%) Query: 1 MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEEDRDELD 60 MA A TP+P+QTLQEEAVCAICLDYF DPVSI CGHNFCR CVTQLW EDEED++E Sbjct: 1 MAGYATTPSPMQTLQEEAVCAICLDYFKDPVSISCGHNFCRGCVTQLWSKEDEEDQNE-- 58 Query: 61 REEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEV-EEEEEGVFWTSGMSRSSWDN 119 EE+E EEE+ EAVGA GWD +R+ Y G+ +EE+ +++++ W ++WDN Sbjct: 59 --EEDEWEEEEDEEAVGAMDGWDGSIREVLYRGNADEELFQDQDDDELWLGDSGITNWDN 116 Query: 120 MDYVW--EEEDEEEDLDYYLGDMEEEDLRGEDEEDEE--EVLEEVEEEDLDP-VTPLPPP 174 +DY+W EEE+EEED DYYLG + DLR + +EE E +E E+E+L P + P P Sbjct: 117 VDYMWDEEEEEEEEDQDYYLGGLRP-DLRIDVYREEEILEAYDEDEDEELYPDIHPPPSL 175 Query: 175 PAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEAL 234 P P + FTCPQCRKSF RRSFRPNLQLANMVQ+IRQM PTP RG+R DQG+C KHQEAL Sbjct: 176 PLPGQ-FTCPQCRKSFTRRSFRPNLQLANMVQIIRQMCPTPYRGNRSNDQGMCFKHQEAL 234 Query: 235 KLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYK 271 KLFCEVD+EAICVVCRESRSHKQHSV+PLEEVVQEY+ Sbjct: 235 KLFCEVDKEAICVVCRESRSHKQHSVLPLEEVVQEYQ 271 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 227 bits (578), Expect = 2e-59 Identities = 123/312 (39%), Positives = 184/312 (58%), Gaps = 8/312 (2%) Query: 179 RCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFC 238 R F CP CRK+ RS RPN QL +MV++ +Q+ ++ D+ +CP+H EAL LFC Sbjct: 62 RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVK---RKIRDESLCPQHHEALSLFC 118 Query: 239 EVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERR 298 D+EA+C++C S +H+ H+VVPL++ QEYK KLQ +EPL + L+ + + K+ EE++ Sbjct: 119 YEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKK 178 Query: 299 VTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAA 358 ELK ++S + EF L R L EEQ L RL E + L R A+ L ++ Sbjct: 179 PGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRR 238 Query: 359 QLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIV 418 L+ L AE + + Q G +L+D+K T +CE+V+ S + + S+ + Sbjct: 239 DLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFAL 298 Query: 419 RKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERR-QEVADHPKRFSADCCVLG 477 RK+ + D+TLDP+TAHP L+LS DR+ V+ E R +++ D P+RF+ CVL Sbjct: 299 RKILKQLI----ADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLA 354 Query: 478 AQGFRSGRHYWE 489 +GF SGRHYWE Sbjct: 355 TEGFTSGRHYWE 366 Score = 60.8 bits (146), Expect = 3e-09 Identities = 23/47 (48%), Positives = 33/47 (70%) Query: 2 AAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 A+ A T ++ LQ EA C++CL+Y +PV I CGHNFC+ C+T+ W Sbjct: 11 ASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWW 57 >gi|21630277 tripartite motif-containing 11 [Homo sapiens] Length = 468 Score = 215 bits (547), Expect = 9e-56 Identities = 122/316 (38%), Positives = 174/316 (55%), Gaps = 20/316 (6%) Query: 177 PRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKL 236 P + CP+CR+ P+R+ RPN LA M ++ R++HP QG+CP H+E L Sbjct: 47 PEGPYACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSP-----VPQGVCPAHREPLAA 101 Query: 237 FCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEE 296 FC + +C C S H H V PL++ ++ KAKL+ +E LRK ++ +A+ + Sbjct: 102 FCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQAD 161 Query: 297 RRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQ 356 + ++S+ V EF RL R LAEE+ L +RL E L R A+ L +Q Sbjct: 162 ETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQ 221 Query: 357 AAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD---PCQPHSHDFL 413 +A L+ L+AE + R Q L LLQDIK+ R ++V+LQPPEV + C+ Sbjct: 222 SAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCR------- 274 Query: 414 TDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADC 473 +V + R R D+TLDPDTA+P L+LS DRR V+ + RQ + D P+RF Sbjct: 275 VPGLVETLRRF-----RGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGP 329 Query: 474 CVLGAQGFRSGRHYWE 489 CVLG + F SGRHYWE Sbjct: 330 CVLGQERFTSGRHYWE 345 Score = 69.3 bits (168), Expect = 8e-12 Identities = 28/42 (66%), Positives = 31/42 (73%) Query: 8 PNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWG 49 P+ LQEEA CAICLDYFTDPV CGHNFCR C+ + WG Sbjct: 4 PDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWG 45 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 214 bits (546), Expect = 1e-55 Identities = 125/342 (36%), Positives = 185/342 (54%), Gaps = 38/342 (11%) Query: 179 RCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFC 238 R F CP CRK+ RS RPN QL +MV++ +Q+ ++ D+ +CP+H EAL LFC Sbjct: 62 RDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVK---RKIRDESLCPQHHEALSLFC 118 Query: 239 EVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERR 298 D+EA+C++C S +H+ H+VVPL++ QEYK KLQ +EPL + L+ + + K+ EE++ Sbjct: 119 YEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKK 178 Query: 299 VTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAA 358 ELK ++S + EF L R L EEQ L RL E + L R A+ L ++ Sbjct: 179 PGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRR 238 Query: 359 QLSRLLAEAQERSQQGGLRLLQDIKETF------------------------------NR 388 L+ L AE + + Q G +L+D+K T NR Sbjct: 239 DLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINR 298 Query: 389 CEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSP 448 CE+V+ S + + S+ +RK+ + D+TLDP+TAHP L+LS Sbjct: 299 CEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLI----ADVTLDPETAHPNLVLSE 354 Query: 449 DRRGVRLAERR-QEVADHPKRFSADCCVLGAQGFRSGRHYWE 489 DR+ V+ E R +++ D P+RF+ CVL +GF SGRHYWE Sbjct: 355 DRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWE 396 Score = 60.8 bits (146), Expect = 3e-09 Identities = 23/47 (48%), Positives = 33/47 (70%) Query: 2 AAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 A+ A T ++ LQ EA C++CL+Y +PV I CGHNFC+ C+T+ W Sbjct: 11 ASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWW 57 >gi|5730009 ret finger protein [Homo sapiens] Length = 513 Score = 214 bits (544), Expect = 2e-55 Identities = 121/325 (37%), Positives = 189/325 (58%), Gaps = 19/325 (5%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CPQCR++FP+R RPN LAN+ Q+++Q+ G + G+C KH+E LKL+CE D Sbjct: 52 SCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPG-GEMGVCEKHREPLKLYCEED 110 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + ICVVC SR H+ HSV+PLEE V+ +K ++Q ++ L++ + ++ +A+ E+ E Sbjct: 111 QMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAE 170 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 L S + E + EF +L L E + L RL E+ A A ++ + + LS Sbjct: 171 LLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLS 230 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHD------FLTD 415 L+A+ +E+ QQ LLQDI +T +R E +++ P + PD Q H FLT+ Sbjct: 231 SLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPD-LQEKIHIFAQKCLFLTE 289 Query: 416 AIVRKMSRM-----------FCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464 ++ + +M Q VD+TLDPDTA+P+L+LS + R VR + +Q++ D Sbjct: 290 SLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPD 349 Query: 465 HPKRFSADCCVLGAQGFRSGRHYWE 489 +P+RF+ CVLG+ F +GRHYWE Sbjct: 350 NPERFNLFPCVLGSPCFIAGRHYWE 374 Score = 53.1 bits (126), Expect = 6e-07 Identities = 17/38 (44%), Positives = 25/38 (65%) Query: 12 QTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWG 49 + LQ+E C +CL YF +P+ + CGHN C C+ + WG Sbjct: 8 ECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWG 45 >gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] Length = 511 Score = 202 bits (514), Expect = 6e-52 Identities = 124/337 (36%), Positives = 180/337 (53%), Gaps = 21/337 (6%) Query: 169 TPLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMH---PTPGR-GSRVTDQ 224 T PP P P CPQCR+ RPN QLA + ++R+ PG GS+ Sbjct: 69 TRAPPFPLP-----CPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAA 123 Query: 225 GI----CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEP 280 C +H E KL+C+ D AICVVC +R H++H+V+PL+E VQE K L+ + Sbjct: 124 RAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRV 183 Query: 281 LRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHE 340 L+K LE + ++ E++ EL QM +E V +EF L FL E++ L RL E+ Sbjct: 184 LKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSR 243 Query: 341 AQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVW 400 + ++L + QLS+L ++ QE +Q+ L LQ+ K T +RC V P Sbjct: 244 EVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTV 303 Query: 401 SPDPCQPHSHDFLTDAIVRKMSRMFCQAAR--------VDLTLDPDTAHPALMLSPDRRG 452 S + + L +++ M + F + R V+LTLDPDTA+P L+LS D +G Sbjct: 304 SSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKG 363 Query: 453 VRLAERRQEVADHPKRFSADCCVLGAQGFRSGRHYWE 489 VRL ER Q++ +HP RF + VL + GF SGRH+WE Sbjct: 364 VRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWE 400 Score = 55.5 bits (132), Expect = 1e-07 Identities = 20/35 (57%), Positives = 27/35 (77%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 LQ EA C+ICL+ F +PVS+ CGH+FCR C+ + W Sbjct: 23 LQGEATCSICLELFREPVSVECGHSFCRACIGRCW 57 >gi|15208660 tripartite motif protein 21 [Homo sapiens] Length = 475 Score = 190 bits (482), Expect = 3e-48 Identities = 110/307 (35%), Positives = 169/307 (55%), Gaps = 12/307 (3%) Query: 183 CPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVDE 242 CP CR+ F ++ RPN QLANMV ++++ G T C H E L LFCE D Sbjct: 51 CPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREG---TQGERCAVHGERLHLFCEKDG 107 Query: 243 EAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTEL 302 +A+C VC +SR H+ H++VPLEE QEY+ KLQ + LR+ E +K++ + + + Sbjct: 108 KALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADW 167 Query: 303 KSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSR 362 K ++++ + + +EF + FL EE+ + L + QL G ++LA+Q+ L Sbjct: 168 KKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQE 227 Query: 363 LLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMS 422 L++E R L LLQ++ R E L+ ++ SP + + V + Sbjct: 228 LISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSP--------ELRSVCHVPGLK 279 Query: 423 RMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQGFR 482 +M + V +TLDPDTA+P L+LS DRR VRL + +Q + + +RF + VLGAQ F Sbjct: 280 KML-RTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFH 338 Query: 483 SGRHYWE 489 SG+HYWE Sbjct: 339 SGKHYWE 345 Score = 51.6 bits (122), Expect = 2e-06 Identities = 20/35 (57%), Positives = 26/35 (74%) Query: 16 EEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGG 50 EE C ICLD F +PVSI CGH+FC+ C++Q+ G Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG 46 >gi|37622899 ring finger protein 137 [Homo sapiens] Length = 485 Score = 186 bits (473), Expect = 3e-47 Identities = 117/324 (36%), Positives = 173/324 (53%), Gaps = 32/324 (9%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 +TCP CR R+ RPN QLAN+V+ +R + PG G + +C +H E LK+FC+ Sbjct: 55 YTCPLCRAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLK---GDLCERHGEKLKMFCKE 111 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 D +C C +S H+ HSVVP+E+V EYK +L +E L+K E K++ E +R Sbjct: 112 DVLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTA 171 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQ--------------AGLERRLRE-MHEAQLGR 345 K Q+++ ++ EF + R L ++Q A L+R E M + +L Sbjct: 172 TWKIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNH 231 Query: 346 AGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPC 405 S L +Q+ L R++AE +ERSQ+ +LQDI+E NR + LQ PE Sbjct: 232 -----SELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPE------- 279 Query: 406 QPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADH 465 P S + TD V + R + D+ LDPDTA+ L++S DR+ V + Q++ D+ Sbjct: 280 -PISLELKTDCRVLGL-REILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDN 337 Query: 466 PKRFSADCCVLGAQGFRSGRHYWE 489 P+RF VLG+Q SGRHYWE Sbjct: 338 PERFYRYNIVLGSQCISSGRHYWE 361 Score = 50.1 bits (118), Expect = 5e-06 Identities = 17/38 (44%), Positives = 26/38 (68%) Query: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 V+ + EE C IC+ + +P+SI CGH+FC C++ LW Sbjct: 7 VEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLW 44 >gi|112421127 tripartite motif-containing 58 [Homo sapiens] Length = 486 Score = 180 bits (457), Expect = 2e-45 Identities = 111/310 (35%), Positives = 161/310 (51%), Gaps = 16/310 (5%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 + CPQCR F FRPN QLA +V+ +R++ G G+R C +H E L FCE Sbjct: 55 YACPQCRGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARR-----CARHGEDLSRFCEE 109 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 DE A+C VC H+ H PL+E Y+ KLQ +E +RK LE +A ++ Sbjct: 110 DEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTV 169 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 K +++ + EF + FLA+E+ RRL A L R + SRL +Q+ L Sbjct: 170 IWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKAL 229 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEV-QLQPPEVWSPDPCQPHSHDFLTDAIVR 419 L E QER Q+ L LL+ ++ +R + V +L+ + P + L A Sbjct: 230 KELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENI----PME------LKTACCI 279 Query: 420 KMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQ 479 R + +VD+ LDP TAHP+L+L+ D R V+ E ++V ++P+RF C+LG Q Sbjct: 280 PGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQ 339 Query: 480 GFRSGRHYWE 489 F SGRHYWE Sbjct: 340 SFSSGRHYWE 349 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 14/112 (12%) Query: 10 PVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDEED-------------R 56 P + L+E+A C +CLD+ +PVS+ CGH+FC C+++ D R Sbjct: 6 PGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFR 65 Query: 57 DELDREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFW 108 R + G E V +G GAG R + D+ EE+E + W Sbjct: 66 PSGFRPNRQLAGLVESVRRLGLGAG-PGARRCARHGEDLSRFCEEDEAALCW 116 >gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] Length = 450 Score = 177 bits (449), Expect = 2e-44 Identities = 110/310 (35%), Positives = 165/310 (53%), Gaps = 16/310 (5%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 F CP+CR+ P+R+ PN L + ++ +Q HP + Q +C +H E LKLFC+ Sbjct: 33 FPCPECREMSPQRNLLPNRLLTKVAEMAQQ-HPG------LQKQDLCQEHHEPLKLFCQK 85 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 D+ ICVVCRESR H+ H V+P EE VQ YK KL+ +E LR+ + ++A+EE+ + Sbjct: 86 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLA 145 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 E + ++K + EF ++ +L EE+ L + L E R + + L Q L Sbjct: 146 EWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSL 205 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 LL + +ERS QG L++LQD+KE +R V +Q PEV P +P + + I + Sbjct: 206 ELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEV--APPTRPRTVCRVPGQI--E 261 Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPK-RFSADCCVLGAQ 479 + R F + D+ D +A+P L+L R+ L + K RF A C +G Sbjct: 262 VLRGFLE----DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQT 317 Query: 480 GFRSGRHYWE 489 F SGRHYWE Sbjct: 318 AFSSGRHYWE 327 Score = 30.4 bits (67), Expect = 4.1 Identities = 9/14 (64%), Positives = 10/14 (71%) Query: 35 CGHNFCRVCVTQLW 48 CGHNFCR C+ W Sbjct: 4 CGHNFCRACIQLSW 17 >gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] Length = 477 Score = 177 bits (449), Expect = 2e-44 Identities = 110/310 (35%), Positives = 165/310 (53%), Gaps = 16/310 (5%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 F CP+CR+ P+R+ PN L + ++ +Q HP + Q +C +H E LKLFC+ Sbjct: 60 FPCPECREMSPQRNLLPNRLLTKVAEMAQQ-HPG------LQKQDLCQEHHEPLKLFCQK 112 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 D+ ICVVCRESR H+ H V+P EE VQ YK KL+ +E LR+ + ++A+EE+ + Sbjct: 113 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLA 172 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 E + ++K + EF ++ +L EE+ L + L E R + + L Q L Sbjct: 173 EWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSL 232 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 LL + +ERS QG L++LQD+KE +R V +Q PEV P +P + + I + Sbjct: 233 ELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEV--APPTRPRTVCRVPGQI--E 288 Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPK-RFSADCCVLGAQ 479 + R F + D+ D +A+P L+L R+ L + K RF A C +G Sbjct: 289 VLRGFLE----DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQT 344 Query: 480 GFRSGRHYWE 489 F SGRHYWE Sbjct: 345 AFSSGRHYWE 354 Score = 63.9 bits (154), Expect = 3e-10 Identities = 25/35 (71%), Positives = 27/35 (77%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 LQEEA C+ICLDYFTDPV CGHNFCR C+ W Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW 44 >gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] Length = 477 Score = 177 bits (449), Expect = 2e-44 Identities = 110/310 (35%), Positives = 165/310 (53%), Gaps = 16/310 (5%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 F CP+CR+ P+R+ PN L + ++ +Q HP + Q +C +H E LKLFC+ Sbjct: 60 FPCPECREMSPQRNLLPNRLLTKVAEMAQQ-HPG------LQKQDLCQEHHEPLKLFCQK 112 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 D+ ICVVCRESR H+ H V+P EE VQ YK KL+ +E LR+ + ++A+EE+ + Sbjct: 113 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLA 172 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 E + ++K + EF ++ +L EE+ L + L E R + + L Q L Sbjct: 173 EWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSL 232 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 LL + +ERS QG L++LQD+KE +R V +Q PEV P +P + + I + Sbjct: 233 ELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEV--APPTRPRTVCRVPGQI--E 288 Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPK-RFSADCCVLGAQ 479 + R F + D+ D +A+P L+L R+ L + K RF A C +G Sbjct: 289 VLRGFLE----DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQT 344 Query: 480 GFRSGRHYWE 489 F SGRHYWE Sbjct: 345 AFSSGRHYWE 354 Score = 63.9 bits (154), Expect = 3e-10 Identities = 25/35 (71%), Positives = 27/35 (77%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 LQEEA C+ICLDYFTDPV CGHNFCR C+ W Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW 44 >gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapiens] Length = 481 Score = 176 bits (446), Expect = 5e-44 Identities = 105/324 (32%), Positives = 173/324 (53%), Gaps = 11/324 (3%) Query: 173 PPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQE 232 P P TCP C++ F SFRPN QLAN+V+ I ++ G + ++ +C +H E Sbjct: 47 PGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLG--LGEEDVCQEHGE 104 Query: 233 ALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMK 292 + FCE DE +CVVCRE+ H H++ LE+ Y+ ++ ++ LRK E +Q+++ Sbjct: 105 KIYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQ 164 Query: 293 AKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASR 352 ++E +R+ L +Q+ ++ V SEF L +FL E+Q+ L +L L + Sbjct: 165 SRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLL 224 Query: 353 LAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDF 412 +A + + S L+ E +E++++ LL DI+ T RCE + + P SP+ Q DF Sbjct: 225 VAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQ-RIRDF 283 Query: 413 LTDAI-VRKMSRMFCQAARVDL-------TLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464 A+ +++ +MF + +L +LDP T+HP L+LS D + + + + Q D Sbjct: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPD 343 Query: 465 HPKRFSADCCVLGAQGFRSGRHYW 488 +P+RF CVL G GRH W Sbjct: 344 NPQRFDRATCVLAHTGITGGRHTW 367 Score = 46.2 bits (108), Expect = 7e-05 Identities = 18/36 (50%), Positives = 24/36 (66%) Query: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQ 46 V +L +E C IC +PV+I CGHNFCR C+T+ Sbjct: 7 VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTR 42 >gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapiens] Length = 395 Score = 176 bits (446), Expect = 5e-44 Identities = 105/324 (32%), Positives = 173/324 (53%), Gaps = 11/324 (3%) Query: 173 PPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQE 232 P P TCP C++ F SFRPN QLAN+V+ I ++ G + ++ +C +H E Sbjct: 47 PGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLG--LGEEDVCQEHGE 104 Query: 233 ALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMK 292 + FCE DE +CVVCRE+ H H++ LE+ Y+ ++ ++ LRK E +Q+++ Sbjct: 105 KIYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQ 164 Query: 293 AKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASR 352 ++E +R+ L +Q+ ++ V SEF L +FL E+Q+ L +L L + Sbjct: 165 SRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLL 224 Query: 353 LAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDF 412 +A + + S L+ E +E++++ LL DI+ T RCE + + P SP+ Q DF Sbjct: 225 VAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQ-RIRDF 283 Query: 413 LTDAI-VRKMSRMFCQAARVDL-------TLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464 A+ +++ +MF + +L +LDP T+HP L+LS D + + + + Q D Sbjct: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPD 343 Query: 465 HPKRFSADCCVLGAQGFRSGRHYW 488 +P+RF CVL G GRH W Sbjct: 344 NPQRFDRATCVLAHTGITGGRHTW 367 Score = 46.2 bits (108), Expect = 7e-05 Identities = 18/36 (50%), Positives = 24/36 (66%) Query: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQ 46 V +L +E C IC +PV+I CGHNFCR C+T+ Sbjct: 7 VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTR 42 >gi|22749269 ring finger protein 129 [Homo sapiens] Length = 471 Score = 176 bits (445), Expect = 6e-44 Identities = 100/318 (31%), Positives = 169/318 (53%), Gaps = 8/318 (2%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 F CP CR FP +SFR N QL N+ ++ +Q+ + R + +C KH + L LFC Sbjct: 51 FPCPVCRFCFPYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVK 110 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 D E +C C S H++H + P+++ ++ L+G +EPLR ++E V+K+ + + Sbjct: 111 DLEILCTQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSV 170 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 ELK +++ + + SEF ++ FL EQ + R++++ L + L++ + L Sbjct: 171 ELKKKVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTL 230 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRK 420 LL E + +S Q L LL K ++ + L+ PE++S + + F Sbjct: 231 KHLLREVEGKSVQSNLELLTQAKSMHHKYQ--NLKCPELFS---FRLTKYGFSLPPQYSG 285 Query: 421 MSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVLGAQG 480 + R+ + +VD+ LD +TAHP L++S DR+ VR +++ + P+RF VLG+Q Sbjct: 286 LDRII-KPFQVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQR 344 Query: 481 FRSGRHYWEEP--KEPSW 496 F SGRHYWE +P W Sbjct: 345 FSSGRHYWEVEVGNKPKW 362 Score = 58.5 bits (140), Expect = 1e-08 Identities = 23/40 (57%), Positives = 29/40 (72%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWGGEDE 53 LQEE+ C ICL+Y DPV+I CGHNFCR C++ W D+ Sbjct: 10 LQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDD 49 >gi|157743261 tripartite motif-containing 75 [Homo sapiens] Length = 468 Score = 168 bits (425), Expect = 1e-41 Identities = 94/313 (30%), Positives = 158/313 (50%), Gaps = 15/313 (4%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 F CP CR FR N QL M+++ + + T + + +C KH + L +FC+ Sbjct: 51 FPCPVCRHQCQEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKE 110 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 D +C +C + H+ H V P+E+ Y+ + +++PL+K L +QK+ + + ++ Sbjct: 111 DLMVLCPLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPL 170 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 EL+ ++++ ++SEF L +FL EQ + RL E + + A + + +A L Sbjct: 171 ELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATL 230 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWS----PDPCQPHSHDFLTDA 416 L++ E S+ L LL IK + E P ++S D C Sbjct: 231 KSQLSKVVELSELSELELLSQIKIFY---ESENESSPSIFSIHLKRDGCSFPPQYSALQR 287 Query: 417 IVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476 I++K +V++ LDP+TAHP L++S D++ VR +R+Q+V PKRF+ VL Sbjct: 288 IIKKF--------KVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVL 339 Query: 477 GAQGFRSGRHYWE 489 G F SGRH+WE Sbjct: 340 GFPYFHSGRHFWE 352 Score = 61.6 bits (148), Expect = 2e-09 Identities = 24/35 (68%), Positives = 28/35 (80%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 LQ EA C+ICLDY +DPV+I CGHNFCR C+ Q W Sbjct: 10 LQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSW 44 >gi|5454014 tripartite motif-containing 38 [Homo sapiens] Length = 465 Score = 158 bits (399), Expect = 1e-38 Identities = 104/313 (33%), Positives = 160/313 (51%), Gaps = 23/313 (7%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGI-CPKHQEALKLFCE 239 F CPQCR F S RPN QL ++++ +++ TDQ + C +H E LFCE Sbjct: 57 FCCPQCRAPFHMDSLRPNKQLGSLIEALKE-----------TDQEMSCEEHGEQFHLFCE 105 Query: 240 VDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRV 299 + + IC C + HK H+ +E+V Q YK KLQ V L++ + + K R+ Sbjct: 106 DEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRI 165 Query: 300 TELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQ 359 T+ K +++ + + S+F L FL EE+ RL + + L R + L ++ + Sbjct: 166 TKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNE 225 Query: 360 LSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD---PCQPHSHDFLTDA 416 L + E +E+ Q +LLQ++ +T +R V+L+ E S + C F Sbjct: 226 LKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYF---- 281 Query: 417 IVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476 V+KM R + +V +TLDPDTAH L+LS DRR V ++ +RF+A CVL Sbjct: 282 DVKKMLR----SHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVL 337 Query: 477 GAQGFRSGRHYWE 489 G +GF SGR Y+E Sbjct: 338 GCEGFTSGRRYFE 350 Score = 51.6 bits (122), Expect = 2e-06 Identities = 18/35 (51%), Positives = 26/35 (74%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 + EEA C+ICL T+PVSI CGH++C +C+T + Sbjct: 10 MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFF 44 >gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapiens] Length = 343 Score = 156 bits (395), Expect = 4e-38 Identities = 84/222 (37%), Positives = 126/222 (56%), Gaps = 7/222 (3%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEV 240 F CP+CR+ P+R+ PN L + ++ +Q HP + Q +C +H E LKLFC+ Sbjct: 60 FPCPECREMSPQRNLLPNRLLTKVAEMAQQ-HPG------LQKQDLCQEHHEPLKLFCQK 112 Query: 241 DEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVT 300 D+ ICVVCRESR H+ H V+P EE VQ YK KL+ +E LR+ + ++A+EE+ + Sbjct: 113 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLA 172 Query: 301 ELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 E + ++K + EF ++ +L EE+ L + L E R + + L Q L Sbjct: 173 EWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSL 232 Query: 361 SRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSP 402 LL + +ERS QG L++LQD+KE +R V +Q PEV P Sbjct: 233 ELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPP 274 Score = 63.9 bits (154), Expect = 3e-10 Identities = 25/35 (71%), Positives = 27/35 (77%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 LQEEA C+ICLDYFTDPV CGHNFCR C+ W Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSW 44 >gi|149193331 tripartite motif protein 15 [Homo sapiens] Length = 465 Score = 154 bits (390), Expect = 1e-37 Identities = 87/270 (32%), Positives = 144/270 (53%), Gaps = 7/270 (2%) Query: 227 CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLE 286 C +H E + FCE D E +CV CRE +H+ H+V L+E +Q Y+ +L+ +E L + Sbjct: 83 CEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERD 142 Query: 287 AVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRA 346 ++ +K +E++++ L +Q++S+ V + F RL + L +++ L RLRE+ + Sbjct: 143 EIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKER 202 Query: 347 GAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQ 406 ++++E+ +L + E +E+ QQ LLQD++ +RCE PE SPD + Sbjct: 203 DEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVK 262 Query: 407 P----HSHDFLTDAIVRKMSRMFCQAARVD---LTLDPDTAHPALMLSPDRRGVRLAERR 459 H ++R S +D +TLDP TA +L+LS DR+ VR ++ Sbjct: 263 KIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQK 322 Query: 460 QEVADHPKRFSADCCVLGAQGFRSGRHYWE 489 + + D P RF VLG GF SGRH W+ Sbjct: 323 KSLPDSPLRFDGLPAVLGFPGFSSGRHRWQ 352 Score = 38.1 bits (87), Expect = 0.020 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 7 TPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQL 47 TP+ ++ + E C +C D V+I CGH FCR+C+ L Sbjct: 4 TPS-LKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPAL 43 >gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] Length = 488 Score = 152 bits (384), Expect = 7e-37 Identities = 100/322 (31%), Positives = 165/322 (51%), Gaps = 16/322 (4%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CP C+ S+ + RPN LAN+V+ +R++ PG+ + +C H E L+LFC+ D Sbjct: 55 SCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAV---LCADHGEKLQLFCQED 111 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + IC +C S+ H+ H +EEV QEY+ K Q ++ L+ + +K+ A + T Sbjct: 112 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 171 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 K+QM+ E + +EF +L L + ++L + + L A + L Q L Sbjct: 172 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 231 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKM 421 L+++ + R Q + LLQD+ + R E L+ PE P + S D +++M Sbjct: 232 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEAL---PTKLRSMFRAPD--LKRM 286 Query: 422 SRMF-----CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476 R+ Q+ VD+TL+P TA+ L+L+ +RR VR + ++ DC VL Sbjct: 287 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVL 345 Query: 477 GAQGFRSGRHYWE--EPKEPSW 496 G+Q F SG+HYWE K+ +W Sbjct: 346 GSQHFSSGKHYWEVDVAKKTAW 367 Score = 51.2 bits (121), Expect = 2e-06 Identities = 19/40 (47%), Positives = 28/40 (70%) Query: 6 MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45 MT + ++EE C ICL+ T+P+SI CGH+FC+ C+T Sbjct: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT 40 >gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] Length = 516 Score = 152 bits (384), Expect = 7e-37 Identities = 100/322 (31%), Positives = 165/322 (51%), Gaps = 16/322 (4%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CP C+ S+ + RPN LAN+V+ +R++ PG+ + +C H E L+LFC+ D Sbjct: 83 SCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAV---LCADHGEKLQLFCQED 139 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + IC +C S+ H+ H +EEV QEY+ K Q ++ L+ + +K+ A + T Sbjct: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 K+QM+ E + +EF +L L + ++L + + L A + L Q L Sbjct: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKM 421 L+++ + R Q + LLQD+ + R E L+ PE P + S D +++M Sbjct: 260 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEAL---PTKLRSMFRAPD--LKRM 314 Query: 422 SRMF-----CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476 R+ Q+ VD+TL+P TA+ L+L+ +RR VR + ++ DC VL Sbjct: 315 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK-HYDCSVL 373 Query: 477 GAQGFRSGRHYWE--EPKEPSW 496 G+Q F SG+HYWE K+ +W Sbjct: 374 GSQHFSSGKHYWEVDVAKKTAW 395 Score = 51.2 bits (121), Expect = 2e-06 Identities = 19/40 (47%), Positives = 28/40 (70%) Query: 6 MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45 MT + ++EE C ICL+ T+P+SI CGH+FC+ C+T Sbjct: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT 68 >gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sapiens] Length = 474 Score = 149 bits (377), Expect = 5e-36 Identities = 100/331 (30%), Positives = 157/331 (47%), Gaps = 42/331 (12%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVI--RQMHPTPGRGSRVTDQGICPKHQEALKLFC 238 F CP+CR + RPN LA + + R++ P P G+C +H E L+LFC Sbjct: 47 FPCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVP--------PGLCGRHWEPLRLFC 98 Query: 239 EVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERR 298 E D+ +C+VCRES+ H+ H++ P++E + Y+ KL L ++ V ++ E + Sbjct: 99 EDDQRPVCLVCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKN 158 Query: 299 VTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAA 358 T+ K ++KS+ +++EF +L FL EE+ +RL + E + +L + A Sbjct: 159 ATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIA 218 Query: 359 QLSRLLAEAQERSQQGGLRLLQDIKETFNRCE--EVQLQPPEVWSPDPCQPHSHDFLTDA 416 L +L+ E E+SQ L LLQ+ KE R E +V V CQ Sbjct: 219 SLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQ--------IP 270 Query: 417 IVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVR------------------LAER 458 ++++M + F +V + L DTAHP L+ S + R V+ R Sbjct: 271 LMKEMLKRF----QVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWR 326 Query: 459 RQEVADHPKRFSADCCVLGAQGFRSGRHYWE 489 + +RF CVLG F SG+HYWE Sbjct: 327 NPQKTAFVERFQHLPCVLGKNVFTSGKHYWE 357 Score = 60.8 bits (146), Expect = 3e-09 Identities = 24/37 (64%), Positives = 28/37 (75%) Query: 12 QTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 + +QEE C ICLDYF DPVSI CGHNFCR C+ + W Sbjct: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW 40 >gi|4508005 tripartite motif-containing 26 [Homo sapiens] Length = 539 Score = 141 bits (356), Expect = 1e-33 Identities = 93/332 (28%), Positives = 166/332 (50%), Gaps = 23/332 (6%) Query: 183 CPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRG-SRVT----DQGICPKHQEALKLF 237 CP C+K F + + RP QLA++V+ I ++ GR VT D +C +H+E L + Sbjct: 53 CPLCKKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYY 112 Query: 238 CEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEER 297 CE D + +CV+CRESR H+ H+ V +E+ Q ++ K+ H+ LR+ + +Q +AK E Sbjct: 113 CEDDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEA 172 Query: 298 RVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQA 357 + +++ + + +EF + +FL E + L +L ++ + SR + Sbjct: 173 DILAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGEL 232 Query: 358 AQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDP----CQPHSHDFL 413 A+L+ +++E + ++QQ L+QD ++ NR + W P + + +F Sbjct: 233 ARLALVISELEGKAQQPAAELMQDTRDFLNRYPR-----KKFWVGKPIARVVKKKTGEFS 287 Query: 414 TDAI-VRKMSRMF-------CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADH 465 + +++ R F + V +TLDP +A L LS D + V + H Sbjct: 288 DKLLSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLH 347 Query: 466 PKRFSADCCVLGAQGFRSGRHYWE-EPKEPSW 496 P++F + VLG++GF G+ YWE E + W Sbjct: 348 PQQFDCEPGVLGSKGFTWGKVYWEVEVEREGW 379 Score = 58.9 bits (141), Expect = 1e-08 Identities = 23/41 (56%), Positives = 30/41 (73%) Query: 7 TPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQL 47 T P+++L+EE C+ICLDY DPV+I CGH FCR C T + Sbjct: 3 TSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDV 43 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/70 (51%), Positives = 41/70 (58%), Gaps = 9/70 (12%) Query: 51 EDEEDRDELDREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYE--GDMEEEVEEEEEGVFW 108 EDEE+ DE EEE EEEE E G G G+D DED E GD EEE EEEEE V Sbjct: 381 EDEEEGDE-----EEEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLE 435 Query: 109 TS--GMSRSS 116 + G++R S Sbjct: 436 SCMVGVARDS 445 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 27/87 (31%) Query: 82 WDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEEDLDYYLG--- 138 W+ + E + D EEE +EEEEG EEE+EEE+ Y G Sbjct: 370 WEVEVEREGWSED-EEEGDEEEEG-------------------EEEEEEEEAGYGDGYDD 409 Query: 139 ---DMEEEDLRGEDEEDEEEVLEEVEE 162 D +EE L G++EE+EEE EEV E Sbjct: 410 WETDEDEESL-GDEEEEEEEEEEEVLE 435 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/78 (41%), Positives = 39/78 (50%), Gaps = 20/78 (25%) Query: 81 GWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEEDLDYYLGDM 140 GW +++ EGD EEE EEEEE G W+ +EDEE LGD Sbjct: 378 GWS----EDEEEGDEEEEGEEEEEEEEAGYGDGYDDWET------DEDEES-----LGDE 422 Query: 141 EEEDLRGEDEEDEEEVLE 158 EEE+ E+EEEVLE Sbjct: 423 EEEE-E----EEEEEVLE 435 Score = 34.3 bits (77), Expect = 0.28 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 15/84 (17%) Query: 51 EDEEDRDEL-DREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWT 109 E +ED + L D EEEEE+ EEE +E+ G D+ R +GD+ E+GV W Sbjct: 411 ETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKR----KGDLS---LRPEDGV-WA 462 Query: 110 SGMSRSSWDNMDYVWEEEDEEEDL 133 +S S +W E +L Sbjct: 463 LRLSSSG------IWANTSPEAEL 480 >gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo sapiens] Length = 500 Score = 137 bits (345), Expect = 2e-32 Identities = 103/357 (28%), Positives = 159/357 (44%), Gaps = 68/357 (19%) Query: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVI--RQMHPTPGRGSRVTDQGICPKHQEALKLFC 238 F CP+CR + RPN LA + + R++ P P G+C +H E L+LFC Sbjct: 47 FPCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVP--------PGLCGRHWEPLRLFC 98 Query: 239 EVDEEAICVVCRESRSHKQHSVVPLEEVVQEYK-AKLQGHVEPLRKHL------------ 285 E D+ +C+VCRES+ H+ H++ P++E + Y+ HV+ ++ L Sbjct: 99 EDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEE 158 Query: 286 -------EAVQKMKA------KEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLE 332 V KMK E + T+ K ++KS+ +++EF +L FL EE+ Sbjct: 159 KLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFL 218 Query: 333 RRLREMHEAQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCE-- 390 +RL + E + +L + A L +L+ E E+SQ L LLQ+ KE R E Sbjct: 219 QRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQ 278 Query: 391 EVQLQPPEVWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDR 450 +V V CQ ++++M + F +V + L DTAHP L+ S + Sbjct: 279 DVNYSLEAVKVKTVCQ--------IPLMKEMLKRF----QVAVNLAEDTAHPKLVFSQEG 326 Query: 451 RGVR------------------LAERRQEVADHPKRFSADCCVLGAQGFRSGRHYWE 489 R V+ R + +RF CVLG F SG+HYWE Sbjct: 327 RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWE 383 Score = 60.8 bits (146), Expect = 3e-09 Identities = 24/37 (64%), Positives = 28/37 (75%) Query: 12 QTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 + +QEE C ICLDYF DPVSI CGHNFCR C+ + W Sbjct: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW 40 >gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo sapiens] Length = 493 Score = 133 bits (335), Expect = 3e-31 Identities = 92/325 (28%), Positives = 160/325 (49%), Gaps = 17/325 (5%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CP CR S+ + RPN +AN+V+ +R++ +P G +V C +H E L LFC+ D Sbjct: 54 SCPVCRISYQPENIRPNRHVANLVEKLREVKLSP-EGQKVDH---CARHGEKLLLFCQED 109 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + IC +C S+ H+ H P EEV QEY+ KLQ +E LR+ + ++++A Sbjct: 110 GKVICWLCERSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKAS 169 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 K+Q++ + V ++F +L L E++ + L + E L + + + +Q L Sbjct: 170 WKTQIQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLR 229 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDFLTDAIVRKM 421 L+++ + R Q + LLQ + R E V L+ PE + + + L + ++ Sbjct: 230 ELISDLEHRLQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGML--EV 287 Query: 422 SRMFCQAAR--VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSA----DCC- 474 R R VD+T+ P+ A ++S D+R V + + R+ + C Sbjct: 288 FRELTDVRRYWVDVTVAPNNISCA-VISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCT 346 Query: 475 -VLGAQGFRSGRHYWE--EPKEPSW 496 +LG+Q SG+HYWE K+ +W Sbjct: 347 GILGSQSITSGKHYWEVDVSKKTAW 371 Score = 47.4 bits (111), Expect = 3e-05 Identities = 16/32 (50%), Positives = 24/32 (75%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45 ++EE C ICL+ T P+S+ CGH+FC+ C+T Sbjct: 9 VKEEVTCPICLELLTQPLSLDCGHSFCQACLT 40 >gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 128 bits (322), Expect = 1e-29 Identities = 96/323 (29%), Positives = 160/323 (49%), Gaps = 24/323 (7%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CP C S+ + N LAN+V+ ++++ +P G + + +C H E L LFC+ D Sbjct: 55 SCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKK---RDLCDHHGEKLLLFCKED 111 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + IC +C S+ H+ H V EEV +E + KLQ ++ L+K E +K++A T Sbjct: 112 RKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTS 171 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 K Q+++E + +EF +L L E+ +RL E + L + A L +Q + Sbjct: 172 WKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVR 231 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD-PCQPHSHDFLTDAIVRK 420 L+++ + RSQ + LLQD+ E +L+ P++ S H+ D + + Sbjct: 232 ELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPD------LSR 285 Query: 421 MSRMFCQAAR-----VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCV 475 M +MF + VD+TL+ + L+LS D+R V V P + + V Sbjct: 286 MLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQ-CYNYGV 338 Query: 476 LGAQGFRSGRHYWE--EPKEPSW 496 LG+Q F SG+HYWE K+ +W Sbjct: 339 LGSQYFSSGKHYWEVDVSKKTAW 361 Score = 49.7 bits (117), Expect = 6e-06 Identities = 17/32 (53%), Positives = 24/32 (75%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45 +QEE C ICL+ T+P+S+ CGH+ CR C+T Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACIT 40 >gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 128 bits (322), Expect = 1e-29 Identities = 96/323 (29%), Positives = 160/323 (49%), Gaps = 24/323 (7%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CP C S+ + N LAN+V+ ++++ +P G + + +C H E L LFC+ D Sbjct: 55 SCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKK---RDLCDHHGEKLLLFCKED 111 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + IC +C S+ H+ H V EEV +E + KLQ ++ L+K E +K++A T Sbjct: 112 RKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTS 171 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 K Q+++E + +EF +L L E+ +RL E + L + A L +Q + Sbjct: 172 WKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVR 231 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD-PCQPHSHDFLTDAIVRK 420 L+++ + RSQ + LLQD+ E +L+ P++ S H+ D + + Sbjct: 232 ELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPD------LSR 285 Query: 421 MSRMFCQAAR-----VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCV 475 M +MF + VD+TL+ + L+LS D+R V V P + + V Sbjct: 286 MLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQ-CYNYGV 338 Query: 476 LGAQGFRSGRHYWE--EPKEPSW 496 LG+Q F SG+HYWE K+ +W Sbjct: 339 LGSQYFSSGKHYWEVDVSKKTAW 361 Score = 49.7 bits (117), Expect = 6e-06 Identities = 17/32 (53%), Positives = 24/32 (75%) Query: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45 +QEE C ICL+ T+P+S+ CGH+ CR C+T Sbjct: 9 VQEEVTCPICLELLTEPLSLDCGHSLCRACIT 40 >gi|51477690 tripartite motif-containing 6 and tripartite motif-containing 34 [Homo sapiens] Length = 842 Score = 128 bits (322), Expect = 1e-29 Identities = 96/323 (29%), Positives = 160/323 (49%), Gaps = 24/323 (7%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CP C S+ + N LAN+V+ ++++ +P G + + +C H E L LFC+ D Sbjct: 409 SCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKK---RDLCDHHGEKLLLFCKED 465 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + IC +C S+ H+ H V EEV +E + KLQ ++ L+K E +K++A T Sbjct: 466 RKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTS 525 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 K Q+++E + +EF +L L E+ +RL E + L + A L +Q + Sbjct: 526 WKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVR 585 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD-PCQPHSHDFLTDAIVRK 420 L+++ + RSQ + LLQD+ E +L+ P++ S H+ D + + Sbjct: 586 ELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPD------LSR 639 Query: 421 MSRMFCQAAR-----VDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCV 475 M +MF + VD+TL+ + L+LS D+R V V P + + V Sbjct: 640 MLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQ-CYNYGV 692 Query: 476 LGAQGFRSGRHYWE--EPKEPSW 496 LG+Q F SG+HYWE K+ +W Sbjct: 693 LGSQYFSSGKHYWEVDVSKKTAW 715 Score = 119 bits (298), Expect = 7e-27 Identities = 66/217 (30%), Positives = 112/217 (51%), Gaps = 3/217 (1%) Query: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 +CP C+ S+ + RPN LAN+V+ +R++ PG+ + +C H E L+LFC+ D Sbjct: 83 SCPVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAV---LCADHGEKLQLFCQED 139 Query: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 + IC +C S+ H+ H +EEV QEY+ K Q ++ L+ + +K+ A + T Sbjct: 140 GKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTS 199 Query: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361 K+QM+ E + +EF +L L + ++L + + L A + L Q L Sbjct: 200 WKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLR 259 Query: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPE 398 L+++ + R Q + LLQD+ + R E L+ PE Sbjct: 260 ELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPE 296 Score = 51.2 bits (121), Expect = 2e-06 Identities = 19/40 (47%), Positives = 28/40 (70%) Query: 6 MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45 MT + ++EE C ICL+ T+P+SI CGH+FC+ C+T Sbjct: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT 68 Score = 51.2 bits (121), Expect = 2e-06 Identities = 19/41 (46%), Positives = 27/41 (65%) Query: 5 AMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVT 45 AM + +QEE C ICL+ T+P+S+ CGH+ CR C+T Sbjct: 354 AMASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACIT 394 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,221,741 Number of Sequences: 37866 Number of extensions: 1388226 Number of successful extensions: 32806 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 623 Number of HSP's successfully gapped in prelim test: 679 Number of HSP's that attempted gapping in prelim test: 14104 Number of HSP's gapped (non-prelim): 8959 length of query: 518 length of database: 18,247,518 effective HSP length: 107 effective length of query: 411 effective length of database: 14,195,856 effective search space: 5834496816 effective search space used: 5834496816 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.