Guide to the Human Genome
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Name: EPAS1 Sequence: fasta or formatted (870aa) NCBI GI: 40254439
Description:

endothelial PAS domain protein 1

Referenced in:

Oxygen Sensing and Hemoglobin

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         53           3
 C cysteine            2.5         22           2
 D aspartate           5.1         44           2
 E glutamate           6.8         59           2
 F phenylalanine       4.4         38           2
 G glycine             5.7         50           2
 H histidine           3.1         27           1
 I isoleucine          3.1         27           2
 K lysine              5.7         50           2
 L leucine            10.0         87           2
 M methionine          3.3         29           1
 N asparagine          3.8         33           2
 P proline             8.0         70           2
 Q glutamine           4.6         40           3
 R arginine            4.0         35           2
 S serine             10.9         95           5
 T threonine           5.7         50           2
 V valine              3.8         33           2
 W tryptophan          0.7          6           1
 Y tyrosine            2.5         22           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   endothelial PAS domain protein 1 
HIF1A                 0.335   hypoxia-inducible factor 1, alpha subunit isoform 1 [...
HIF1A                 0.333   hypoxia-inducible factor 1, alpha subunit isoform 2 ...
HIF3A                 0.216   hypoxia inducible factor 3, alpha subunit isoform c ...
HIF3A                 0.215   hypoxia inducible factor 3, alpha subunit isoform a ...
HIF3A                 0.177   hypoxia inducible factor 3, alpha subunit isoform b ...
SIM2                  0.125   single-minded homolog 2 long isoform 
SIM2                  0.125   single-minded homolog 2 short isoform 
SIM1                  0.124   single-minded homolog 1 
NPAS3                 0.116   neuronal PAS domain protein 3 isoform 1 
NPAS3                 0.113   neuronal PAS domain protein 3 isoform 2 
NPAS1                 0.100   neuronal PAS domain protein 1 
ARNTL2                0.068   aryl hydrocarbon receptor nuclear translocator-like ...
CLOCK                 0.064   clock 
ARNTL                 0.063   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.063   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.063   aryl hydrocarbon receptor nuclear translocator-like ...
ARNT2                 0.063   aryl hydrocarbon receptor nuclear translocator 2 [Ho...
NPAS2                 0.063   neuronal PAS domain protein 2 
ARNT                  0.063   aryl hydrocarbon receptor nuclear translocator isofor...
ARNT                  0.062   aryl hydrocarbon receptor nuclear translocator isofo...
AHR                   0.047   aryl hydrocarbon receptor 
NPAS4                 0.036   neuronal PAS domain protein 4 
ARNT                  0.030   aryl hydrocarbon receptor nuclear translocator isofo...
NCOA2                 0.027   nuclear receptor coactivator 2 
NCOA3                 0.025   nuclear receptor coactivator 3 isoform a 
NCOA3                 0.025   nuclear receptor coactivator 3 isoform b 
NCOA1                 0.024   nuclear receptor coactivator 1 isoform 2 
NCOA1                 0.024   nuclear receptor coactivator 1 isoform 3 
NCOA1                 0.024   nuclear receptor coactivator 1 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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