Guide to the Human Genome
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Name: HIF1A Sequence: fasta or formatted (735aa) NCBI GI: 31077211
Description:

hypoxia-inducible factor 1, alpha subunit isoform 2

Referenced in:

Oxygen Sensing and Hemoglobin

Other entries for this name:
alt prot [826aa] hypoxia-inducible factor 1, alpha subunit isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         38           2
 C cysteine            1.6         12           1
 D aspartate           6.9         51           3
 E glutamate           7.5         55           3
 F phenylalanine       3.3         24           2
 G glycine             3.7         27           2
 H histidine           2.9         21           2
 I isoleucine          4.4         32           2
 K lysine              6.3         46           3
 L leucine             9.4         69           2
 M methionine          3.5         26           1
 N asparagine          3.9         29           1
 P proline             6.3         46           2
 Q glutamine           5.2         38           2
 R arginine            4.2         31           2
 S serine              9.4         69           3
 T threonine           8.3         61           4
 V valine              5.0         37           2
 W tryptophan          0.3          2           1
 Y tyrosine            2.9         21           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hypoxia-inducible factor 1, alpha subunit isoform 2 ... 
HIF1A                 0.999   hypoxia-inducible factor 1, alpha subunit isoform 1 [...
EPAS1                 0.403   endothelial PAS domain protein 1 
HIF3A                 0.261   hypoxia inducible factor 3, alpha subunit isoform c ...
HIF3A                 0.260   hypoxia inducible factor 3, alpha subunit isoform a ...
HIF3A                 0.217   hypoxia inducible factor 3, alpha subunit isoform b ...
SIM2                  0.172   single-minded homolog 2 long isoform 
SIM2                  0.172   single-minded homolog 2 short isoform 
SIM1                  0.168   single-minded homolog 1 
NPAS3                 0.153   neuronal PAS domain protein 3 isoform 1 
NPAS3                 0.148   neuronal PAS domain protein 3 isoform 2 
NPAS1                 0.129   neuronal PAS domain protein 1 
ARNTL                 0.077   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.077   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.077   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL2                0.077   aryl hydrocarbon receptor nuclear translocator-like ...
CLOCK                 0.072   clock 
ARNT                  0.072   aryl hydrocarbon receptor nuclear translocator isofo...
NPAS2                 0.071   neuronal PAS domain protein 2 
ARNT                  0.070   aryl hydrocarbon receptor nuclear translocator isofor...
ARNT2                 0.068   aryl hydrocarbon receptor nuclear translocator 2 [Ho...
AHR                   0.066   aryl hydrocarbon receptor 
NPAS4                 0.045   neuronal PAS domain protein 4 
NCOA2                 0.034   nuclear receptor coactivator 2 
NCOA1                 0.034   nuclear receptor coactivator 1 isoform 2 
NCOA1                 0.034   nuclear receptor coactivator 1 isoform 3 
NCOA1                 0.034   nuclear receptor coactivator 1 isoform 1 
ARNT                  0.034   aryl hydrocarbon receptor nuclear translocator isofo...
NCOA3                 0.030   nuclear receptor coactivator 3 isoform a 
NCOA3                 0.030   nuclear receptor coactivator 3 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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