Search of human proteins with 39652628

Search of human proteins with 39652628

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39652628 oxidative stress-associated Src activator [Homo
sapiens]
         (1118 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39652628 oxidative stress-associated Src activator [Homo sapi...  2300   0.0  
gi|157388908 hypothetical protein LOC54954 [Homo sapiens]            1084   0.0  
gi|149363702 hypothetical protein LOC445577 [Homo sapiens]            254   2e-67
gi|24308334 family with sequence similarity 120B [Homo sapiens]       130   9e-30
gi|146134388 YLP motif containing 1 [Homo sapiens]                     47   8e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    46   2e-04
gi|161016767 mucin 21 [Homo sapiens]                                   44   9e-04
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        44   0.001
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      43   0.001
gi|4557853 transcription factor SOX9 [Homo sapiens]                    43   0.001
gi|71040090 regulatory factor X, 5 [Homo sapiens]                      43   0.001
gi|4557843 regulatory factor X, 5 [Homo sapiens]                       43   0.001
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    43   0.002
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    43   0.002
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    43   0.002
gi|57864582 hornerin [Homo sapiens]                                    42   0.002
gi|193788649 retinoic acid induced 2 [Homo sapiens]                    42   0.003
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]          42   0.003
gi|55750053 atrophin-1 [Homo sapiens]                                  42   0.004
gi|55750041 atrophin-1 [Homo sapiens]                                  42   0.004
gi|208022661 hypothetical protein LOC57701 [Homo sapiens]              41   0.006
gi|41349472 PR domain containing 16 isoform 2 [Homo sapiens]           41   0.007
gi|41349470 PR domain containing 16 isoform 1 [Homo sapiens]           41   0.007
gi|91208420 bassoon protein [Homo sapiens]                             41   0.007
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         40   0.012
gi|186928829 dermokine isoform 4 precursor [Homo sapiens]              40   0.012
gi|186928827 dermokine isoform 5 precursor [Homo sapiens]              40   0.012
gi|186928825 dermokine isoform 3 precursor [Homo sapiens]              40   0.012
gi|33504489 dermokine isoform 2 precursor [Homo sapiens]               40   0.012
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                40   0.012

>gi|39652628 oxidative stress-associated Src activator [Homo sapiens]
          Length = 1118

 Score = 2300 bits (5961), Expect = 0.0
 Identities = 1118/1118 (100%), Positives = 1118/1118 (100%)

Query: 1    MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGG 60
            MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGG
Sbjct: 1    MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGG 60

Query: 61   FYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQ 120
            FYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQ
Sbjct: 61   FYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQ 120

Query: 121  QIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFH 180
            QIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFH
Sbjct: 121  QIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFH 180

Query: 181  GLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALL 240
            GLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALL
Sbjct: 181  GLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALL 240

Query: 241  GNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTSDLD 300
            GNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTSDLD
Sbjct: 241  GNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTSDLD 300

Query: 301  AIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKPMSFHPPHYLAARPGPFGMPGMVPPHV 360
            AIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKPMSFHPPHYLAARPGPFGMPGMVPPHV
Sbjct: 301  AIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKPMSFHPPHYLAARPGPFGMPGMVPPHV 360

Query: 361  PPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSN 420
            PPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSN
Sbjct: 361  PPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSN 420

Query: 421  IPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKI 480
            IPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKI
Sbjct: 421  IPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKI 480

Query: 481  GWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPIPCLLSMPTRNH 540
            GWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPIPCLLSMPTRNH
Sbjct: 481  GWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPIPCLLSMPTRNH 540

Query: 541  MDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAAL 600
            MDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAAL
Sbjct: 541  MDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAAL 600

Query: 601  LYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVE 660
            LYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVE
Sbjct: 601  LYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVE 660

Query: 661  ALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLR 720
            ALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLR
Sbjct: 661  ALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLR 720

Query: 721  YMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMA 780
            YMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMA
Sbjct: 721  YMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMA 780

Query: 781  LFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQ 840
            LFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQ
Sbjct: 781  LFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQ 840

Query: 841  SVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGE 900
            SVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGE
Sbjct: 841  SVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGE 900

Query: 901  TVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGS 960
            TVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGS
Sbjct: 901  TVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGS 960

Query: 961  RRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPY 1020
            RRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPY
Sbjct: 961  RRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPY 1020

Query: 1021 AASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESA 1080
            AASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESA
Sbjct: 1021 AASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESA 1080

Query: 1081 LNNDSKTCNTNPHLNALSTDSACRREAALEAAVLNKEE 1118
            LNNDSKTCNTNPHLNALSTDSACRREAALEAAVLNKEE
Sbjct: 1081 LNNDSKTCNTNPHLNALSTDSACRREAALEAAVLNKEE 1118


>gi|157388908 hypothetical protein LOC54954 [Homo sapiens]
          Length = 1096

 Score = 1084 bits (2803), Expect = 0.0
 Identities = 609/1098 (55%), Positives = 731/1098 (66%), Gaps = 129/1098 (11%)

Query: 39   PPQTP-LRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACF---GGNIELFV 94
            PPQ P  R+LVDA + L RLYGG+ TDWV GGQWN MLGYL+AL +AC    G  +EL V
Sbjct: 110  PPQLPGARVLVDAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVV 169

Query: 95   FFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIR 154
             F G L K RL EW +R   ERQTAQ IV HV NKGTPPP+ WFLPP C++HC+RLALIR
Sbjct: 170  MFPGGLGKDRLAEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIR 229

Query: 155  FHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTT 214
            F VKV QS+EDHH EV+ F RENGFHGL+A+DS+YAL NIP Y+S+HALKLS NGK+LTT
Sbjct: 230  FRVKVFQSLEDHHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTT 289

Query: 215  SQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQL 274
            +Q+LM EVAKQL L    FPIFAALLGNHILPDEDLA+FHWSLLGPEHPLASLKVRAHQL
Sbjct: 290  NQFLMQEVAKQLGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQL 349

Query: 275  VLPPCDVVIKAVADYVRNIQDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKP 334
            VLPPCDVVIKAV++YV +I+D S+LD + KDVF+ SQSRT+DK+ RFK+A+ YYS T+K 
Sbjct: 350  VLPPCDVVIKAVSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKL 409

Query: 335  MSFHP-PHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPV-APQVPSPGGAPGQGP 392
             S    P +L  R    G P        P   N   T    KP+ + QVP     P   P
Sbjct: 410  SSLPVGPSFLGFRNNRLGNP--------PLPRNQVGTISAGKPMFSHQVPQKVKYPP--P 459

Query: 393  YPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAY 452
            +P   +     +L  S   L E +++S  P   +++P    +   + + S  PN++ S  
Sbjct: 460  FPVGPNS----SLLFSSHALGESHAFSEDPML-QNSPFANWAVSYDSSASQFPNYLPSKA 514

Query: 453  FP----GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSST 508
             P     SS SSSSD DE +G +++HI+           H +P+     G+  +  GS  
Sbjct: 515  SPPLGPDSSHSSSSDGDEPNGASSDHIT--------EAFHHQPEW----GNPNRDRGSWA 562

Query: 509  ASSGSQLAEGKGSQMGTVQP-IPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGL 567
                + ++E   + +G  +P IP LLSM TRNHMDIT PPLPPVAPEVLRVAEHRH++GL
Sbjct: 563  QPVDTGVSE---ASLGDGEPHIPSLLSMSTRNHMDITIPPLPPVAPEVLRVAEHRHRRGL 619

Query: 568  MYPYIFHVLTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLA 627
            MYPYI+HVLTKGEIKI V IEDE N +LPPAALL+R  RQYVYGVLFSLAE+++K ERLA
Sbjct: 620  MYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQYVYGVLFSLAETQRKMERLA 679

Query: 628  FRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRR 687
             R+ RLP E   VI+KEW+AYKGKSPQTPELV AL FREWTCPNLK+LWLGKAVEDKNRR
Sbjct: 680  MRR-RLPVEVPSVILKEWSAYKGKSPQTPELVSALTFREWTCPNLKKLWLGKAVEDKNRR 738

Query: 688  MRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPK 747
            MRAFLACM+SDTP+MLNPANVPTHL+++CCVLRYMVQWPG RIL R ELD FLAQA+S +
Sbjct: 739  MRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGRILHRHELDTFLAQAVSTQ 798

Query: 748  LYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLF 807
            LYEPD+LQELKIE LD RGIQL+ALFMSGVD ALFANDACGQP+PWEHCCPW+YFDGKLF
Sbjct: 799  LYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQPVPWEHCCPWIYFDGKLF 858

Query: 808  QSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFSR--QSHTLPFPP--PPAL 863
            QSKL+KA RE+  L++LCDGQAD A KVEKMRQS+LEG++ +    S  LP P   PP +
Sbjct: 859  QSKLIKAGRERVSLVELCDGQADLATKVEKMRQSILEGVNMNHPPPSALLPSPTFVPPMV 918

Query: 864  P-FYPASAYPRHFGPVP-PSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGA 921
            P  YP S Y R  G +P P QGR RGFAG                               
Sbjct: 919  PSLYPVSLYSRAMGSMPLPPQGRSRGFAG------------------------------- 947

Query: 922  FSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPA 981
                           + PIP QGGKLEIAG VVG WAGSR  R GRG F +QVVSVGGP 
Sbjct: 948  ---------------LHPIPPQGGKLEIAGMVVGQWAGSRSSR-GRGSFGMQVVSVGGPG 991

Query: 982  RGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSS 1041
            +G  +           GRG + + +G K             S++ V+K L+   G S+S 
Sbjct: 992  KGHGK--------EQTGRGSKGHKKGNKQ-----------GSSDGVSKSLELHQGRSRSQ 1032

Query: 1042 AMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESALNNDSKTCNT-NPHLNALSTD 1100
               + G+L     + EEK          D R P+ S+ AL+ DS  CN  N +L   + +
Sbjct: 1033 VNGNSGAL-----IKEEK---------SDHRLPAPSQCALSRDSNECNNGNRYLPMNNRE 1078

Query: 1101 SACRREAALEAAVLNKEE 1118
                +E  LE     KE+
Sbjct: 1079 KNHLQEQKLETVAQRKED 1096



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 21/28 (75%), Positives = 25/28 (89%)

Query: 1  MGVQGFQDYIEKHCPSAVVPVELQKLAR 28
          MGVQGFQ+++EK CP AVVPV+L KLAR
Sbjct: 1  MGVQGFQEFLEKRCPGAVVPVDLLKLAR 28


>gi|149363702 hypothetical protein LOC445577 [Homo sapiens]
          Length = 196

 Score =  254 bits (650), Expect = 2e-67
 Identities = 127/147 (86%), Positives = 130/147 (88%), Gaps = 5/147 (3%)

Query: 352 MPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKN 411
           MPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKN
Sbjct: 1   MPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKN 60

Query: 412 LTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGA 471
           LTEQNSYSNIPHEGKHTPLYERS PINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGA
Sbjct: 61  LTEQNSYSNIPHEGKHTPLYERSLPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGA 120

Query: 472 TNHISGNKIGWEKTGSH---SEPQARG 495
           T +      G+  T  H    + QARG
Sbjct: 121 TKYTI--YWGFRATDHHVQGRDSQARG 145


>gi|24308334 family with sequence similarity 120B [Homo sapiens]
          Length = 910

 Score =  130 bits (326), Expect = 9e-30
 Identities = 85/265 (32%), Positives = 131/265 (49%), Gaps = 22/265 (8%)

Query: 554 EVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVL 613
           E+L+VA   H +   Y  ++++++ GEI+ + ++EDE ++ LP  A +YRP+RQ VY +L
Sbjct: 575 EILKVARTHHVQAESY-LVYNIMSSGEIECSNTLEDELDQALPSQAFIYRPIRQRVYSLL 633

Query: 614 FSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFR-EWTCPNL 672
               +    T                + +KEW  Y G   + P+LV  L        P+L
Sbjct: 634 LEDCQDVTST---------------CLAVKEWFVYPGNPLRHPDLVRPLQMTIPGGTPSL 678

Query: 673 KRLWLGKAVEDKNRRMRAFLACMR-SDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARIL 731
           K LWL +  E + RR+   LAC   S +   L     P     LCC+L Y+        L
Sbjct: 679 KILWLNQEPEIQVRRLDTLLACFNLSSSREELQAVESP--FQALCCLLIYLFVQVDTLCL 736

Query: 732 RRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPI 791
             ++L AF+AQAL  +     QL  L+ + ++PR +QL +L + G+   +  N ACG P 
Sbjct: 737 --EDLHAFIAQALCLQGKSTSQLVNLQPDYINPRAVQLGSLLVRGLTTLVLVNSACGFPW 794

Query: 792 PWEHCCPWMYFDGKLFQSKLLKASR 816
                 PW  FDGKLF  K L++ +
Sbjct: 795 KTSDFMPWNVFDGKLFHQKYLQSEK 819



 Score =  103 bits (256), Expect = 1e-21
 Identities = 72/258 (27%), Positives = 115/258 (44%), Gaps = 11/258 (4%)

Query: 1   MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGG 60
           MGV+G Q ++   CP     V  ++LA        R + P     ++VDA  CL   Y  
Sbjct: 1   MGVRGLQGFVGSTCPHICTVVNFKELAEHH-----RSKYPGCTPTIVVDAMCCLRYWYTP 55

Query: 61  FYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQ 120
               W+ GGQW      L    K      I+L  FF+G +E+ +  EWVKR+    +   
Sbjct: 56  --ESWICGGQWREYFSALRDFVKTFTAAGIKLIFFFDGMVEQDKRDEWVKRRLKNNREIS 113

Query: 121 QIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFH 180
           +I  ++++    P +  F  P  +A   R AL     +   S+++   EV  +  ++   
Sbjct: 114 RIFHYIKSHKEQPGRNMFFIPSGLAVFTRFALKTLGQETLCSLQEADYEVASYGLQHNCL 173

Query: 181 GLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALL 240
           G++  D+DY + +   YFS   L L    +SL T      ++ + L L     P+ A LL
Sbjct: 174 GILGEDTDYLIYDTCPYFSISELCL----ESLDTVMLCREKLCESLGLCVADLPLLACLL 229

Query: 241 GNHILPDEDLASFHWSLL 258
           GN I+P+    SF +  L
Sbjct: 230 GNDIIPEGMFESFRYKCL 247


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 60/219 (27%), Positives = 83/219 (37%), Gaps = 13/219 (5%)

Query: 334 PMSFHPPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPY 393
           P S  PP    A P     PGM PP +PP +     TS+    + P + S G  P   P 
Sbjct: 539 PPSLPPPVMPPALPATVPPPGMPPPVMPPSL----PTSVPPPGMPPSLSSAGPPPVLPPP 594

Query: 394 PYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYF 453
             S + P P+ L     + T       +P     TP      P      G P  + +A  
Sbjct: 595 SLSSAGPPPV-LPPPSLSSTAPPPVMPLPPLSSATP--PPGIPPPGVPQGIPPQLTAAPV 651

Query: 454 PGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQ--TKAEGSSTASS 511
           P +S+S SS   E    A      +      T  H   Q+ G P +Q  +KA  S +A  
Sbjct: 652 PPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAG-PSEQVNSKAPLSKSALP 710

Query: 512 GSQLAEGKG---SQMGTVQPIPCLLSMPTRNHMDITTPP 547
            S  +  +G   S     QPI  +  MP R+   +  PP
Sbjct: 711 YSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPP 749



 Score = 30.4 bits (67), Expect = 9.8
 Identities = 29/107 (27%), Positives = 38/107 (35%), Gaps = 1/107 (0%)

Query: 354 GMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLT 413
           GM+P     Q    P TSL  +   PQ   P  A GQ       S+  PL+ +      T
Sbjct: 810 GMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADT 869

Query: 414 EQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSS 460
             N   N   +     +      +  AQS + N  DS   P  S  S
Sbjct: 870 SSNQQKNFKMQSAAFSIAADVKDVKAAQS-NENLSDSQQEPPKSEVS 915


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 50/186 (26%), Positives = 61/186 (32%), Gaps = 21/186 (11%)

Query: 329 SATSKPMSFHPPHYLAARPGPFGMPGMVPP-HVPP-------QMLNIPQTSLQAKPVAPQ 380
           S    P+   PPH    +P P   P   PP H PP       Q    P     +KPV  Q
Sbjct: 54  SGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQ 113

Query: 381 VPSPGGAPGQGPYPYSLSEPAPLTLDTS--------GKNLTEQNSYSNIPHEGKHTPLYE 432
            P P  APG G  P + S   P T  TS        G   T   + ++ P          
Sbjct: 114 GPGP--APGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPS 171

Query: 433 RSSPINPAQSGSPNHVDSAY---FPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHS 489
              P  P Q+G P    +A     PG          +G         G   G    G H 
Sbjct: 172 SGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHP 231

Query: 490 EPQARG 495
           +P  RG
Sbjct: 232 KPPHRG 237



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 5/99 (5%)

Query: 347 PGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLD 406
           PGP G  G  PP +PP   +  Q     +   PQ P P   P   P P+   +P P   D
Sbjct: 49  PGP-GQSGPKPP-IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH-PQPHQQQQPPPPPQD 105

Query: 407 TSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSP 445
           +S K +  Q      P  G   P    + P  P  SG+P
Sbjct: 106 SS-KPVVAQGP-GPAPGVGSAPPASSSAPPATPPTSGAP 142



 Score = 30.4 bits (67), Expect = 9.8
 Identities = 25/96 (26%), Positives = 31/96 (32%), Gaps = 9/96 (9%)

Query: 879 PPSQGRGRGFAGVCGFGGPYGETVATGP---------YRAFRVAAASGHCGAFSGSDSSR 929
           P  +    G  G    G PYG      P         Y A      +   G+  GSD   
Sbjct: 605 PRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRT 664

Query: 930 TSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRG 965
               QGG  P+  QG +    GT  G+  G     G
Sbjct: 665 ERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEG 700


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 3/118 (2%)

Query: 407 TSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDN-- 464
           TS +  T  NS S+    G  T     SS ++   S + N   S    G+ST+++S++  
Sbjct: 158 TSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRT 217

Query: 465 -DEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGS 521
              G+G ATN  S        T ++SE               SST SSG+  A    S
Sbjct: 218 TSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSES 275



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 4/138 (2%)

Query: 407 TSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDE 466
           TS    T  NS S+    G  T     SS  +   S + N   S    G+ST+++S++  
Sbjct: 323 TSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESST 382

Query: 467 GSGG---ATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQM 523
            S G   AT   S        T ++SE               SST SSG+  A   GS +
Sbjct: 383 VSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSV 442

Query: 524 GTV-QPIPCLLSMPTRNH 540
            +       L  M T +H
Sbjct: 443 TSAGSGTAALTGMHTTSH 460



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 7/156 (4%)

Query: 369 QTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHT 428
           ++S  +   +    S    P  G    + SE +     TS    T  NS S+    G  T
Sbjct: 229 ESSTTSSGASTATNSESSTPSSGAGTATNSESST----TSSGAGTATNSESSTVSSGIST 284

Query: 429 PLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGA---TNHISGNKIGWEKT 485
                SS  +   + + N   S    G++T+++SD+   S GA   TN  S        T
Sbjct: 285 VTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAST 344

Query: 486 GSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGS 521
            ++SE              GSST SSG+  A    S
Sbjct: 345 ATNSESSTTSSGASTATNSGSSTTSSGTSTATNSES 380



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 3/110 (2%)

Query: 416 NSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGA---T 472
           NS S+    G  T     SS  +   S + N   S    G+ST+++SD+   S  A   T
Sbjct: 107 NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT 166

Query: 473 NHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQ 522
           N  S        T ++SE               SST SSG+  A    S+
Sbjct: 167 NSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESR 216



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 3/118 (2%)

Query: 407 TSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDE 466
           TS    T  NS S+ P  G  T     SS  +   S + N   S     +ST+++S++  
Sbjct: 113 TSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESST 172

Query: 467 GSGGA---TNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGS 521
            S GA   TN  S        T ++SE               S T S+G+  A    S
Sbjct: 173 TSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSES 230



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 35/121 (28%), Positives = 46/121 (38%), Gaps = 10/121 (8%)

Query: 407 TSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDE 466
           +SG N T  NS S+    G +T     SS  +   S + N   S    G+ST   + N E
Sbjct: 294 SSGAN-TATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAST---ATNSE 349

Query: 467 ------GSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKG 520
                 G+  ATN  S        T ++SE               SST SSG+  A    
Sbjct: 350 SSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSE 409

Query: 521 S 521
           S
Sbjct: 410 S 410



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 9/135 (6%)

Query: 396 SLSEPAPLTLDTSGKNLTEQ------NSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVD 449
           S++     T   SG ++T        NS  +    G  T      S ++   S + N   
Sbjct: 51  SVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSES 110

Query: 450 SAYFPGSSTSSSSDNDEGSGGA---TNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGS 506
           S    G+ST+++S++   S GA   TN  S        T ++S+               S
Sbjct: 111 STTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSES 170

Query: 507 STASSGSQLAEGKGS 521
           ST SSG+  A    S
Sbjct: 171 STTSSGASTATNSES 185



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 32/118 (27%), Positives = 43/118 (36%), Gaps = 3/118 (2%)

Query: 407 TSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDE 466
           TS    T  NS  +    G        SS  +   S + N   S    G+ST+++SD+  
Sbjct: 83  TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSST 142

Query: 467 GSGGA---TNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGS 521
            S GA   TN  S        T ++SE               SST SS +  A    S
Sbjct: 143 TSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSES 200


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 38/148 (25%), Positives = 57/148 (38%), Gaps = 21/148 (14%)

Query: 339  PPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLS 398
            PP YL  +      P   PP +P Q+ +IP     A PV P        P  GP  Y+L 
Sbjct: 1279 PPPYLPPQQPSLPPPPQQPPPLP-QLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLG 1337

Query: 399  EPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPI---------NPAQSGSPNHVD 449
             P       +G        +      G+H PL++ +SP+          PA    P H  
Sbjct: 1338 RPGRAPRRGAG-------GHPQFAPHGRH-PLHQPTSPLPLYSPAPQHPPAHKQGPKHFI 1389

Query: 450  SAYFPGSSTSSSSDNDEGS---GGATNH 474
             ++ P    ++ +    GS   GG+ +H
Sbjct: 1390 FSHHPQMMPAAGAAGGPGSRPPGGSYSH 1417



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 37/155 (23%), Positives = 50/155 (32%), Gaps = 39/155 (25%)

Query: 339  PPHYLAARPG-----------PFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPS---- 383
            P HY   RPG            F   G  P H P   L +   + Q  P   Q P     
Sbjct: 1331 PQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIF 1390

Query: 384  ---------------PGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHT 428
                           PG  P  G Y +     +PL+  +    +    SY  +P    HT
Sbjct: 1391 SHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSP---IPPHPSYPPLPPPSPHT 1447

Query: 429  PLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSD 463
            P     SP+ P     P H      PG++   S++
Sbjct: 1448 P----HSPLPPTSPHGPLHASGP--PGTANPPSAN 1476


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/224 (28%), Positives = 73/224 (32%), Gaps = 36/224 (16%)

Query: 877  PVPPSQGRGRGFAGVCGFGGP---------YGETVATGPYRAFRVAAASGHCGAF----- 922
            P PP     RG AGV GF GP          GE    GP  A   A   G  GA      
Sbjct: 565  PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624

Query: 923  ---SGSDSSRTSKSQGGVQPIPSQGGKLEIAGT-----VVGHWA--GSRRGRGGRGPFPL 972
               +G    +      G Q +P   G    AG      V G     G    RG RG FP 
Sbjct: 625  AGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG-FPG 683

Query: 973  QVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPP-YAASAEEVAKEL 1031
            +    G P    PRG    P     G  G     G       QG P       E  A  L
Sbjct: 684  ERGVQGPPGPAGPRGANGAP-----GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738

Query: 1032 KSKSGE-SKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAP 1074
                G+   +    +DGS  ++GV     P     G  G A AP
Sbjct: 739  PGPKGDRGDAGPKGADGSPGKDGVRGLTGPI----GPPGPAGAP 778



 Score = 37.4 bits (85), Expect = 0.080
 Identities = 55/212 (25%), Positives = 72/212 (33%), Gaps = 24/212 (11%)

Query: 877  PVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGG 936
            P  P     RG  G  G  GP G T   GP        A G     +G    R S+   G
Sbjct: 313  PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGE----AGPQGPRGSEGPQG 368

Query: 937  VQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGP-ARG--RPRGVISTPV 993
            V+  P   G    AG      A  + G  G    P    + G P ARG   P+G    P 
Sbjct: 369  VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428

Query: 994  IRTFGRGGRYYGRGYKNQAAIQGRP-------PYAASAEEVAKELKSKSGES-------K 1039
             +  G  G     G K     +G P       P   + EE  +  + + G +       +
Sbjct: 429  PK--GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGE 486

Query: 1040 SSAMSSDGSLAENGVMAEEKPAPQMNGSTGDA 1071
                 S G    +GV   + PA +  GS G A
Sbjct: 487  RGGPGSRGFPGADGVAGPKGPAGE-RGSPGPA 517



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 48/186 (25%), Positives = 62/186 (33%), Gaps = 22/186 (11%)

Query: 348  GPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDT 407
            GP G PG V P  PP            +  +P    P GAPG  P P  ++    + +  
Sbjct: 914  GPAGRPGEVGPPGPP--------GPAGEKGSPGADGPAGAPGT-PGPQGIAGQRGV-VGL 963

Query: 408  SGKNLTEQNSYSNIP----HEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSD 463
             G+    +  +  +P      GK  P         P   G P     A  PG S    + 
Sbjct: 964  PGQR--GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG---LAGPPGESGREGAP 1018

Query: 464  NDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQM 523
              EGS G      G K    +TG    P A G PG            SG +   G     
Sbjct: 1019 GAEGSPGRDGS-PGAKGDRGETGPAGPPGAPGAPG--APGPVGPAGKSGDRGETGPAGPA 1075

Query: 524  GTVQPI 529
            G V P+
Sbjct: 1076 GPVGPV 1081



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 45/163 (27%), Positives = 53/163 (32%), Gaps = 33/163 (20%)

Query: 858  PPPPALPFYPASAYPRHFGPVPPSQGRG----------------RGFAGVCGFGGPYGET 901
            P  PA P  P  A     GP  P   RG                RGF+G+ G  GP G  
Sbjct: 1071 PAGPAGPVGPVGAR----GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126

Query: 902  VATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSR 961
               GP  A   A   G  G+         +   G + P P   G+   AG V     G  
Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGP-PGPRGRTGDAGPV-----GPP 1180

Query: 962  RGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYY 1004
               G  GP        G P+ G     +  P       GGRYY
Sbjct: 1181 GPPGPPGP-------PGPPSAGFDFSFLPQPPQEKAHDGGRYY 1216



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 42/158 (26%), Positives = 54/158 (34%), Gaps = 20/158 (12%)

Query: 876  GPV-PPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFS--GSDSSRTSK 932
            GP+ PP      G  G  G  GP G T A G           G  G     G+D    +K
Sbjct: 767  GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826

Query: 933  SQGGVQPIPSQGGKLEIAGTV-----VGHWA--GSRRGRGGRGP-----FPLQVVSVGGP 980
             + G        G    AG       +G+    G++  RG  GP     FP     VG P
Sbjct: 827  GEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP 886

Query: 981  ARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRP 1018
                  G    P     G  G+  G+G + +    GRP
Sbjct: 887  GPSGNAGPPGPP-----GPAGKEGGKGPRGETGPAGRP 919



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 50/187 (26%), Positives = 61/187 (32%), Gaps = 20/187 (10%)

Query: 344 AARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPL 403
           A  PG  G PG    +  P +   P       P  PQ   PGG P  GP   S    AP 
Sbjct: 385 AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ--GPGGPP--GPKGNSGEPGAPG 440

Query: 404 TL-DTSGKN----LTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSST 458
           +  DT  K     +  Q        EGK      R +   P  +G P        PGS  
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGK------RGARGEPGPTGLPGPPGERGGPGSRG 494

Query: 459 SSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQ-TKAEGSSTASSGSQLAE 517
              +D   G  G     +G +      G    P   G PG+         T S GS   +
Sbjct: 495 FPGADGVAGPKGP----AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPD 550

Query: 518 GKGSQMG 524
           GK    G
Sbjct: 551 GKTGPPG 557



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 49/202 (24%), Positives = 60/202 (29%), Gaps = 37/202 (18%)

Query: 886  RGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGG 945
            +G  G  G  GP G+T   GP      A   G      G      ++ Q GV   P   G
Sbjct: 538  KGLTGSPGSPGPDGKTGPPGP------AGQDGR----PGPPGPPGARGQAGVMGFPGPKG 587

Query: 946  KLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYG 1005
                        A    G+ G    P    +VG   +    G    P     G  G    
Sbjct: 588  ------------AAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP--GPAGPAGERGE 633

Query: 1006 RGYKNQAAIQGRPPYAASAEEVAKELK-----SKSGESKSSAMSSDGSLAENGVMAEEKP 1060
            +G       QG P  A    E  K  +            S A    G   E GV     P
Sbjct: 634  QGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGP 693

Query: 1061 --------APQMNGSTGDARAP 1074
                    AP  +G+ GDA AP
Sbjct: 694  AGPRGANGAPGNDGAKGDAGAP 715



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 60/229 (26%), Positives = 77/229 (33%), Gaps = 35/229 (15%)

Query: 858  PPPPALPFYPASAYPRHFGPVPPSQGRG-RGFAGVCGFGGPYGETVATGPYRAFRVAAAS 916
            PP PA P  P    P   G V     +G RG AG  G  G  G     GP      A   
Sbjct: 840  PPGPAGPAGP----PGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895

Query: 917  GHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVS 976
            G  G  +G +  +  + + G    P + G     G      AG +   G  GP       
Sbjct: 896  GPPGP-AGKEGGKGPRGETGPAGRPGEVGPPGPPGP-----AGEKGSPGADGP------- 942

Query: 977  VGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRP----PYAASAEE------ 1026
             G P    P+G+     +   G  G+   RG+       G P    P  AS E       
Sbjct: 943  AGAPGTPGPQGIAGQRGV--VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 1027 VAKELKSKSGES-KSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAP 1074
                L    GES +  A  ++GS   +G       A    G TG A  P
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDG----SPGAKGDRGETGPAGPP 1045



 Score = 30.4 bits (67), Expect = 9.8
 Identities = 47/195 (24%), Positives = 66/195 (33%), Gaps = 19/195 (9%)

Query: 347 PGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPG-----------GAPGQ-GPYP 394
           PGP G PG      PP     P  S    P  P  P PG           G PG+ GP  
Sbjct: 190 PGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGP-PGKNGDDGEAGKPGRPGERGPPG 248

Query: 395 YSLSEPAPLTLDTSGKNLTEQNSYSNIPH-EGKHTPLYERSSPINPAQSGSPNHVDSAYF 453
              +   P T    G  +     +S +   +G   P   +  P +P ++G+P  +     
Sbjct: 249 PQGARGLPGTAGLPG--MKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL 306

Query: 454 PGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGS 513
           PG      +    G+ G  +  +G       TG    P   G  G   K E       GS
Sbjct: 307 PGERGRPGAPGPAGARG-NDGATGAAGPPGPTGPAGPPGFPGAVG--AKGEAGPQGPRGS 363

Query: 514 QLAEGKGSQMGTVQP 528
           +  +G   + G   P
Sbjct: 364 EGPQGVRGEPGPPGP 378


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 36/139 (25%), Positives = 58/139 (41%), Gaps = 10/139 (7%)

Query: 357 PPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNL-TEQ 415
           PP  PPQ    PQ   Q +   PQ P+   AP Q P  ++L+  +     +   ++ TEQ
Sbjct: 345 PPQQPPQAPPAPQAPPQPQAAPPQQPA---APPQQPQAHTLTTLSSEPGQSQRTHIKTEQ 401

Query: 416 NSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHI 475
            S S+   + +H+P     SP N        H   +Y P + +     + + S    +H 
Sbjct: 402 LSPSHYSEQQQHSPQQIAYSPFNLP------HYSPSYPPITRSQYDYTDHQNSSSYYSHA 455

Query: 476 SGNKIGWEKTGSHSEPQAR 494
           +G   G   T ++  P  R
Sbjct: 456 AGQGTGLYSTFTYMNPAQR 474


>gi|71040090 regulatory factor X, 5 [Homo sapiens]
          Length = 616

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 59/233 (25%), Positives = 85/233 (36%), Gaps = 36/233 (15%)

Query: 376 PVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSS 435
           P  P +P PG  PG+ P P  L++P        G    +Q  +          P+ E S 
Sbjct: 386 PTVPALPGPGPGPGRAP-PGGLTQPRGTENREVGIG-GDQGPHDKGVKRTAEVPVSEASG 443

Query: 436 PINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSG----------GATNHISGNKIGWEKT 485
              PA++   +  D+A               GSG           A      +++ WE  
Sbjct: 444 QAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWETW 503

Query: 486 GSHSEPQARGD---PGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPIPCLLSMPTRNHMD 542
           GS  E  + G    PG   +AE       G+ LA+G+G   GTV         P   H  
Sbjct: 504 GSGGEGNSAGGAERPGPMGEAE------KGAVLAQGQGD--GTVSKGG---RGPGSQHTK 552

Query: 543 ITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDL 595
                +P V  +V  +   R +K   +P     L KGE+  A     + NKDL
Sbjct: 553 EAEDKIPLVPSKVSVIKGSRSQKE-AFP-----LAKGEVDTA----PQGNKDL 595


>gi|4557843 regulatory factor X, 5 [Homo sapiens]
          Length = 616

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 59/233 (25%), Positives = 85/233 (36%), Gaps = 36/233 (15%)

Query: 376 PVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSS 435
           P  P +P PG  PG+ P P  L++P        G    +Q  +          P+ E S 
Sbjct: 386 PTVPALPGPGPGPGRAP-PGGLTQPRGTENREVGIG-GDQGPHDKGVKRTAEVPVSEASG 443

Query: 436 PINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSG----------GATNHISGNKIGWEKT 485
              PA++   +  D+A               GSG           A      +++ WE  
Sbjct: 444 QAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWETW 503

Query: 486 GSHSEPQARGD---PGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPIPCLLSMPTRNHMD 542
           GS  E  + G    PG   +AE       G+ LA+G+G   GTV         P   H  
Sbjct: 504 GSGGEGNSAGGAERPGPMGEAE------KGAVLAQGQGD--GTVSKGG---RGPGSQHTK 552

Query: 543 ITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDL 595
                +P V  +V  +   R +K   +P     L KGE+  A     + NKDL
Sbjct: 553 EAEDKIPLVPSKVSVIKGSRSQKE-AFP-----LAKGEVDTA----PQGNKDL 595


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 49/182 (26%), Positives = 60/182 (32%), Gaps = 27/182 (14%)

Query: 348 GPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDT 407
           GP G PG   P  PP    +P   +Q  P  P +P P G PG    P    +P P  LD 
Sbjct: 802 GPNGQPG---PMGPP---GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 408 SGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEG 467
            G                   P  ER SP  P   G      S   PG + +S     +G
Sbjct: 856 PG-------------------PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 468 SGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTK-AEGSSTASSGSQLAEGKGSQMGTV 526
             G      G        G    P  +GD G Q +      T   GS+   G     G +
Sbjct: 897 EMGMMGP-PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM 955

Query: 527 QP 528
            P
Sbjct: 956 DP 957



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 46/178 (25%), Positives = 59/178 (33%), Gaps = 16/178 (8%)

Query: 335  MSFHPPHYLAARPGPFGMPGMV-PPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPY 393
            M F  P  +   PGP G+PG    P +P Q  +     + +  + P +P P G PG   Y
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL-PGLPGPKGEPGLPGY 1090

Query: 394  P------YSLSEPA-PLTLDTSG-KNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSP 445
            P       S+ +P  P    T G K       +   P  G   P      P NP   G P
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP--GPPGPKGISGPPGNPGLPGEP 1148

Query: 446  NHVDSAYFPGSSTSSSSDNDEGSGG----ATNHISGNKIGWEKTGSHSEPQARGDPGD 499
              V     PG           G  G    A       + G+   G    P   G  GD
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD 1206



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 11/56 (19%)

Query: 340 PHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPG---QGP 392
           P  +   PGP G+PG + P  PP         L   P  P +P P G  G   QGP
Sbjct: 178 PPGIQGLPGPTGIPGPIGPPGPP--------GLMGPPGPPGLPGPKGNMGLNFQGP 225



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 40/153 (26%), Positives = 47/153 (30%), Gaps = 29/153 (18%)

Query: 346  RPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTL 405
            +PG FG PG  PP +P          L   P  P +P P G PG   +P     P P   
Sbjct: 1186 QPG-FGNPG--PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP--- 1239

Query: 406  DTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDND 465
                               G   P  E     NP   G P       F G          
Sbjct: 1240 ------------------PGSPGPALEGPKG-NPGPQGPPGRPGPTGFQGLPGPEGPPGL 1280

Query: 466  EGSGGATNHISGNKIGWEKTGSHSEPQARGDPG 498
             G+GG    I G K    + G    P  +GD G
Sbjct: 1281 PGNGG----IKGEKGNPGQPGLPGLPGLKGDQG 1309


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 49/182 (26%), Positives = 60/182 (32%), Gaps = 27/182 (14%)

Query: 348 GPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDT 407
           GP G PG   P  PP    +P   +Q  P  P +P P G PG    P    +P P  LD 
Sbjct: 802 GPNGQPG---PMGPP---GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 408 SGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEG 467
            G                   P  ER SP  P   G      S   PG + +S     +G
Sbjct: 856 PG-------------------PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 468 SGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTK-AEGSSTASSGSQLAEGKGSQMGTV 526
             G      G        G    P  +GD G Q +      T   GS+   G     G +
Sbjct: 897 EMGMMGP-PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM 955

Query: 527 QP 528
            P
Sbjct: 956 DP 957



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 46/178 (25%), Positives = 59/178 (33%), Gaps = 16/178 (8%)

Query: 335  MSFHPPHYLAARPGPFGMPGMV-PPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPY 393
            M F  P  +   PGP G+PG    P +P Q  +     + +  + P +P P G PG   Y
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL-PGLPGPKGEPGLPGY 1090

Query: 394  P------YSLSEPA-PLTLDTSG-KNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSP 445
            P       S+ +P  P    T G K       +   P  G   P      P NP   G P
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP--GPPGPKGISGPPGNPGLPGEP 1148

Query: 446  NHVDSAYFPGSSTSSSSDNDEGSGG----ATNHISGNKIGWEKTGSHSEPQARGDPGD 499
              V     PG           G  G    A       + G+   G    P   G  GD
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD 1206



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 11/56 (19%)

Query: 340 PHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPG---QGP 392
           P  +   PGP G+PG + P  PP         L   P  P +P P G  G   QGP
Sbjct: 178 PPGIQGLPGPTGIPGPIGPPGPP--------GLMGPPGPPGLPGPKGNMGLNFQGP 225


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 49/182 (26%), Positives = 60/182 (32%), Gaps = 27/182 (14%)

Query: 348 GPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDT 407
           GP G PG   P  PP    +P   +Q  P  P +P P G PG    P    +P P  LD 
Sbjct: 802 GPNGQPG---PMGPP---GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855

Query: 408 SGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEG 467
            G                   P  ER SP  P   G      S   PG + +S     +G
Sbjct: 856 PG-------------------PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 468 SGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTK-AEGSSTASSGSQLAEGKGSQMGTV 526
             G      G        G    P  +GD G Q +      T   GS+   G     G +
Sbjct: 897 EMGMMGP-PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM 955

Query: 527 QP 528
            P
Sbjct: 956 DP 957



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 46/178 (25%), Positives = 59/178 (33%), Gaps = 16/178 (8%)

Query: 335  MSFHPPHYLAARPGPFGMPGMV-PPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPY 393
            M F  P  +   PGP G+PG    P +P Q  +     + +  + P +P P G PG   Y
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL-PGLPGPKGEPGLPGY 1090

Query: 394  P------YSLSEPA-PLTLDTSG-KNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSP 445
            P       S+ +P  P    T G K       +   P  G   P      P NP   G P
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP--GPPGPKGISGPPGNPGLPGEP 1148

Query: 446  NHVDSAYFPGSSTSSSSDNDEGSGG----ATNHISGNKIGWEKTGSHSEPQARGDPGD 499
              V     PG           G  G    A       + G+   G    P   G  GD
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD 1206



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 11/56 (19%)

Query: 340 PHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPG---QGP 392
           P  +   PGP G+PG + P  PP         L   P  P +P P G  G   QGP
Sbjct: 178 PPGIQGLPGPTGIPGPIGPPGPP--------GLMGPPGPPGLPGPKGNMGLNFQGP 225


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 12/101 (11%)

Query: 422 PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIG 481
           P  G+H   + RSS   P  SGS       +   SS  SS     GSG      SG+  G
Sbjct: 437 PSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSG------SGHSSG 490

Query: 482 WEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQ 522
             + GS S   +RG+       +GSS  SS S    G GS+
Sbjct: 491 HGQHGSRSGQSSRGE------RQGSSAGSSSSYGQHGSGSR 525



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 32/104 (30%), Positives = 43/104 (41%), Gaps = 12/104 (11%)

Query: 422  PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIG 481
            P  G+H     RSS      SG        +   SS  SSS +  GSG      SG+  G
Sbjct: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG------SGHSSG 1192

Query: 482  WEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGT 525
            + + GS S   +RG+        GSS+ SS      G GS+  +
Sbjct: 1193 YGQHGSRSGQSSRGE------RHGSSSGSSSHYGQHGSGSRQSS 1230



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 32/104 (30%), Positives = 43/104 (41%), Gaps = 12/104 (11%)

Query: 422  PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIG 481
            P  G+H     RSS      SG        +   SS  SSS +  GSG      SG+  G
Sbjct: 2549 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG------SGHSSG 2602

Query: 482  WEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGT 525
            + + GS S   +RG+        GSS+ SS      G GS+  +
Sbjct: 2603 YGQHGSRSGQSSRGE------RHGSSSGSSSHYGQHGSGSRQSS 2640



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 32/104 (30%), Positives = 43/104 (41%), Gaps = 12/104 (11%)

Query: 422  PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIG 481
            P  G+H     RSS      SG        +   SS  SSS +  GSG      SG+  G
Sbjct: 1609 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG------SGHSSG 1662

Query: 482  WEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGT 525
            + + GS S   +RG+        GSS+ SS      G GS+  +
Sbjct: 1663 YGQHGSRSGQSSRGE------RHGSSSRSSSRYGQHGSGSRQSS 1700



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 8/103 (7%)

Query: 422 PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIG 481
           P+ G+H     +SS  +   SGS      +    SS  SS  +  GSG      SG+  G
Sbjct: 203 PNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSG------SGHSSG 256

Query: 482 WEKTGSHSEPQARGDPGDQTKAEGSSTA--SSGSQLAEGKGSQ 522
           + + GS S   +RG+    +    SS     SGS+ + G G Q
Sbjct: 257 YGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQ 299



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 31/104 (29%), Positives = 42/104 (40%), Gaps = 12/104 (11%)

Query: 422  PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIG 481
            P  G+H     RSS       G        +   SS  SSS +  GSG      SG+  G
Sbjct: 2079 PSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSG------SGHSSG 2132

Query: 482  WEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGT 525
            + + GS S   +RG+        GSS+ SS      G GS+  +
Sbjct: 2133 YGQHGSRSGQSSRGE------RHGSSSGSSSRYGQHGSGSRQSS 2170



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 35/108 (32%), Positives = 45/108 (41%), Gaps = 13/108 (12%)

Query: 422  PHEGKHTPLYERSSPINPAQSGSPNHVDSA-YFPGSSTSSSSDNDEGSG----GATNHIS 476
            P  G+H      SS      SGS     S  +  GS  SS   + E S     G T H S
Sbjct: 1360 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS 1419

Query: 477  GN--KIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQ 522
            G+     +E+ GS S   +RG+        GSS+ SS S    G GS+
Sbjct: 1420 GSGHSSSYEQHGSRSGQSSRGE------RHGSSSGSSSSYGQHGSGSR 1461



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 12/81 (14%)

Query: 442  SGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQT 501
            SGS       +   SS  SS     GSG      SG+   +E+ GS S   +RG+     
Sbjct: 1863 SGSGQSSGFGHHESSSWQSSGYTQHGSG------SGHSSSYEQHGSRSGQSSRGE----- 1911

Query: 502  KAEGSSTASSGSQLAEGKGSQ 522
               GSS+ SS S    G GS+
Sbjct: 1912 -QHGSSSGSSSSYGQHGSGSR 1931



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 12/81 (14%)

Query: 442  SGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQT 501
            SGS       +   SS  SS     GSG      SG+   +E+ GS S   +RG+     
Sbjct: 2333 SGSGQSSGFGHHESSSWQSSGYTQHGSG------SGHSSSYEQHGSRSGQSSRGE----- 2381

Query: 502  KAEGSSTASSGSQLAEGKGSQ 522
               GSS+ SS S    G GS+
Sbjct: 2382 -RHGSSSGSSSSYGQHGSGSR 2401



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 32/101 (31%), Positives = 41/101 (40%), Gaps = 13/101 (12%)

Query: 422 PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIG 481
           P  G+H     RSS      SGS       +   SS  SS     GSG      SG+   
Sbjct: 904 PSYGRHGSGSGRSSSSGRHGSGSGQSSGFGH-KSSSGQSSGYTQHGSG------SGHSSS 956

Query: 482 WEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQ 522
           +E+ GS S   +R +        GSS+ SS S    G GS+
Sbjct: 957 YEQHGSRSGQSSRSEQ------HGSSSGSSSSYGQHGSGSR 991



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 16/112 (14%)

Query: 422 PHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSD---NDEGSG---GATNHI 475
           P  G+H   +  SS     Q GS +   S+  P  S S  S    +  GSG   G + H 
Sbjct: 660 PSRGRHGSDFGHSSSYG--QHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHG 717

Query: 476 SGNK--IGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGT 525
           SG+    G+ K GS S   +R +        GSS+  S S    G GS   +
Sbjct: 718 SGSSHSSGYRKHGSRSGQSSRSEQ------HGSSSGLSSSYGQHGSGSHQSS 763



 Score = 30.8 bits (68), Expect = 7.5
 Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 4/99 (4%)

Query: 422  PHEGKHTPLYERSSPINPAQSGSP-NHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKI 480
            P  G+H     +SS  +P  SGS  +     Y  GSS SS   + E   G +   SG   
Sbjct: 1479 PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQS---SGYGQ 1535

Query: 481  GWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGK 519
                +G  S     G    Q+ + G   ASSG   + G+
Sbjct: 1536 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1574



 Score = 30.8 bits (68), Expect = 7.5
 Identities = 33/121 (27%), Positives = 45/121 (37%), Gaps = 15/121 (12%)

Query: 408  SGKNLTEQNSYSNIPHE---GKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDN 464
            SG++ +     S + H    G+H     RSS   P +S S +          S  SS+ +
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS 1768

Query: 465  DEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMG 524
              GSG  + H           G H     +    DQ   EGSST  S S    G GS   
Sbjct: 1769 QHGSG--SGHFCSQ-------GQHGSTSGQSSTFDQ---EGSSTGQSSSHGQHGSGSSQS 1816

Query: 525  T 525
            +
Sbjct: 1817 S 1817



 Score = 30.8 bits (68), Expect = 7.5
 Identities = 53/212 (25%), Positives = 73/212 (34%), Gaps = 24/212 (11%)

Query: 880  PSQGRGRGFAGVCGFGGPYGE----TVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQG 935
            PS+GR    +G     GPYG     + + GPY      + SGH     G   SR+ +S G
Sbjct: 1949 PSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYE-----SGSGHSSGL-GHRESRSGQSSG 2002

Query: 936  GVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIR 995
              Q   S  G     G   G  +G     G  G    Q  S G    G  +   S+   R
Sbjct: 2003 YGQH-GSSSGHSSTHGQ-HGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ---SSGYGR 2057

Query: 996  TFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSSAMSSDGSLAENGVM 1055
                 G+  G G +   + Q  P Y            S SG S SS     G    +G  
Sbjct: 2058 QGSGSGQSPGHGQRGSGSRQS-PSYGRHG--------SGSGRSSSSGQHGPGLGESSGFG 2108

Query: 1056 AEEKPAPQMNGSTGDARAPSHSESALNNDSKT 1087
              E  + Q +  +       HS     + S++
Sbjct: 2109 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2140


>gi|193788649 retinoic acid induced 2 [Homo sapiens]
          Length = 530

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 51/200 (25%), Positives = 67/200 (33%), Gaps = 38/200 (19%)

Query: 339 PPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLS 398
           PP Y    P PF  P  + P VPP  L +P   +   PV   +P P   P      +S S
Sbjct: 206 PPGYAPVPPQPFSSP--LSPLVPPATLLVPYPVIVPLPVPVPIPIPIPMPQSSESKFSSS 263

Query: 399 EPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSST 458
            P P             +S+   P +G  TPL      + P     P      YF     
Sbjct: 264 FPKP------------PSSFGLHPFKGTQTPL--EKDELKPFDILQPKE----YF---QL 302

Query: 459 SSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGD---------------PGDQTKA 503
           S  +    GS      +S   + W K G  S P  + D               P +    
Sbjct: 303 SRHTVIKMGSENEALDLSMKSVPWLKAGEVSPPIFQEDAALDLSVAAHRKSEPPPETLYD 362

Query: 504 EGSSTASSGSQLAEGKGSQM 523
            G+S  SSG  + E   S M
Sbjct: 363 SGASVDSSGHTVMEKLPSGM 382


>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
          Length = 845

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 52/199 (26%), Positives = 77/199 (38%), Gaps = 24/199 (12%)

Query: 356 VPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAP-----GQGPYPYSLSEPAPLTLDTSGK 410
           VPP         P TS  ++   P  PS G +      G GP+P S +   P T  T G 
Sbjct: 461 VPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGG 520

Query: 411 NLTEQNSYSNIP----HEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTS----SSS 462
               +NS S+ P     +   TP    S P+ P    S +H  +    G++ +    +S 
Sbjct: 521 PPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQ 580

Query: 463 DNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGS- 521
                 G +T+H      G    G+   P+A      Q    G  T++S      G G+ 
Sbjct: 581 PMPPSMGTSTSHQPATPGG----GTAQTPEA---GTSQPMPPGMGTSTSHQPTTPGGGTA 633

Query: 522 ---QMGTVQPIPCLLSMPT 537
              + GT QP+P   S P+
Sbjct: 634 QTPEPGTSQPMPLSKSTPS 652



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 49/190 (25%), Positives = 66/190 (34%), Gaps = 23/190 (12%)

Query: 369 QTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHT 428
           Q S Q  P     PSP      GP+  + SE  P   + S    T  +     PH    T
Sbjct: 450 QVSEQEPPSTDVPPSPEAGGTTGPWTSTTSE-VPRPPEPSQGPSTTSSGGGTGPHPPSGT 508

Query: 429 PLYERSSPINPAQSGSPNHVD-SAYFPGSSTS------SSSDNDEGSGGATNHISGNKIG 481
            L   +S       G+ N        PG  T+      +S     G G +T+H      G
Sbjct: 509 TLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSG 568

Query: 482 WEKTGSHSEPQARGDPG-DQTKAEGSSTASSGSQLAEGKGS----QMGTVQPIPCLLSMP 536
               G+   P    +PG  Q       T++S      G G+    + GT QP+P    M 
Sbjct: 569 ----GTAQTP----EPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMP--PGMG 618

Query: 537 TRNHMDITTP 546
           T      TTP
Sbjct: 619 TSTSHQPTTP 628


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 55/208 (26%), Positives = 76/208 (36%), Gaps = 27/208 (12%)

Query: 353 PGMVPPHVPPQM--------LNIPQTSLQAKPVAPQVPSPGGAPGQGP--YPYSLSEPA- 401
           PG  PPH  PQ+        L+ P    +    A  V  P G     P   P S+S    
Sbjct: 210 PGAPPPH--PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267

Query: 402 -------PLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFP 454
                  P T    G NL      +N PH   + P      P+N A S SP  + +   P
Sbjct: 268 SGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA-SASPPGLGAQPLP 326

Query: 455 GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGS-HSEPQARGD-PGDQTKAEGSSTASSG 512
           G   S  +   +G GG      G + G     S HS P A    P    +   SS++SS 
Sbjct: 327 GHLPSPHA-MGQGMGGLP---PGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382

Query: 513 SQLAEGKGSQMGTVQPIPCLLSMPTRNH 540
           +  +    S   +  P P   ++P+  H
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPH 410



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 30/107 (28%), Positives = 43/107 (40%), Gaps = 18/107 (16%)

Query: 853 HTLP-FPPPPAL-PFYPASAYPRHFGP------VPPSQGRGRGFAGVCGFGGPYGETVAT 904
           H  P  PPPPAL P   ASA P   G       +P     G+G  G+   G   G T+A 
Sbjct: 296 HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP-GPEKGPTLAP 354

Query: 905 GPYRAFRVAAAS---------GHCGAFSGSDSSRTSKSQGGVQPIPS 942
            P+     ++++             + S + SS +S S     P P+
Sbjct: 355 SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 55/208 (26%), Positives = 76/208 (36%), Gaps = 27/208 (12%)

Query: 353 PGMVPPHVPPQM--------LNIPQTSLQAKPVAPQVPSPGGAPGQGP--YPYSLSEPA- 401
           PG  PPH  PQ+        L+ P    +    A  V  P G     P   P S+S    
Sbjct: 210 PGAPPPH--PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267

Query: 402 -------PLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFP 454
                  P T    G NL      +N PH   + P      P+N A S SP  + +   P
Sbjct: 268 SGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA-SASPPGLGAQPLP 326

Query: 455 GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGS-HSEPQARGD-PGDQTKAEGSSTASSG 512
           G   S  +   +G GG      G + G     S HS P A    P    +   SS++SS 
Sbjct: 327 GHLPSPHA-MGQGMGGLP---PGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382

Query: 513 SQLAEGKGSQMGTVQPIPCLLSMPTRNH 540
           +  +    S   +  P P   ++P+  H
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPH 410



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 30/107 (28%), Positives = 43/107 (40%), Gaps = 18/107 (16%)

Query: 853 HTLP-FPPPPAL-PFYPASAYPRHFGP------VPPSQGRGRGFAGVCGFGGPYGETVAT 904
           H  P  PPPPAL P   ASA P   G       +P     G+G  G+   G   G T+A 
Sbjct: 296 HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP-GPEKGPTLAP 354

Query: 905 GPYRAFRVAAAS---------GHCGAFSGSDSSRTSKSQGGVQPIPS 942
            P+     ++++             + S + SS +S S     P P+
Sbjct: 355 SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401


>gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
          Length = 1334

 Score = 41.2 bits (95), Expect = 0.006
 Identities = 52/188 (27%), Positives = 71/188 (37%), Gaps = 36/188 (19%)

Query: 350 FGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQV-PSPGGAPGQG-PYPYSLSEPAPLTLDT 407
           F  P   PP  P Q+   PQ +L+  P AP+V  SPG  P    P  Y    P   +LD 
Sbjct: 567 FRGPSPEPPPSPLQVPTYPQLTLEV-PQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDK 625

Query: 408 SGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEG 467
           +G         S  PH G+ TP    +S   P+Q        S   PG   S+   +   
Sbjct: 626 AG---------SESPHPGRRTP---GNSSKKPSQG-------SGRRPGDPGSTPLRDRLA 666

Query: 468 SGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQL---------AEG 518
           + G         +G EK G  + P       ++T+  G S  S+G  +          E 
Sbjct: 667 ALGKLKTGPEGALGSEKNGVPARPGT-----EKTRGPGKSGESAGDMVPSIHRPLEQLEA 721

Query: 519 KGSQMGTV 526
           KG   G V
Sbjct: 722 KGGIRGAV 729


>gi|41349472 PR domain containing 16 isoform 2 [Homo sapiens]
          Length = 1256

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 38/180 (21%)

Query: 332 SKPMSFHPPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPV----APQVPSPGGA 387
           S P S  PP + A  PG    PG+ PP + P+   +P TSL   P+      ++PSP G 
Sbjct: 497 SLPFSTAPPTFPALTPG---FPGIFPPSLYPRPPLLPPTSLLKSPLNHTQDAKLPSPLGN 553

Query: 388 PGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNH 447
           P              L L ++  N ++  + +  P E   + L    S +   ++ S + 
Sbjct: 554 PA-------------LPLVSAVSNSSQGTTAAAGPEEKFESRL--EDSCVEKLKTRSSDM 598

Query: 448 VDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSS 507
            D + F   +T++ +D D  +G               TGS  +     DP D+ K +G S
Sbjct: 599 SDGSDFEDVNTTTGTDLDTTTG---------------TGSDLDSDVDSDP-DKDKGKGKS 642


>gi|41349470 PR domain containing 16 isoform 1 [Homo sapiens]
          Length = 1275

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 38/180 (21%)

Query: 332 SKPMSFHPPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPV----APQVPSPGGA 387
           S P S  PP + A  PG    PG+ PP + P+   +P TSL   P+      ++PSP G 
Sbjct: 497 SLPFSTAPPTFPALTPG---FPGIFPPSLYPRPPLLPPTSLLKSPLNHTQDAKLPSPLGN 553

Query: 388 PGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNH 447
           P              L L ++  N ++  + +  P E   + L    S +   ++ S + 
Sbjct: 554 PA-------------LPLVSAVSNSSQGTTAAAGPEEKFESRL--EDSCVEKLKTRSSDM 598

Query: 448 VDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSS 507
            D + F   +T++ +D D  +G               TGS  +     DP D+ K +G S
Sbjct: 599 SDGSDFEDVNTTTGTDLDTTTG---------------TGSDLDSDVDSDP-DKDKGKGKS 642


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 43/155 (27%), Positives = 55/155 (35%), Gaps = 12/155 (7%)

Query: 339 PPHYLAARPGPFGMPGM-VPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSL 397
           PP      PGP   PG   PP  P     +P          P VP PG  PG GP P S 
Sbjct: 17  PPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGST 76

Query: 398 SEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSS 457
           S      LD   + L  Q + S  P +   T     S     AQ  +    D     G  
Sbjct: 77  SR----RLDPK-EPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEAD-----GPR 126

Query: 458 TSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQ 492
            +   D+     G +  +S ++ G   T  +S PQ
Sbjct: 127 RTLQVDSRTQRSGRSPSVSPDR-GSTPTSPYSVPQ 160


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 44/175 (25%), Positives = 53/175 (30%), Gaps = 25/175 (14%)

Query: 326  GYYSATSKPMSFHPPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPG 385
            G      +P  + PP +    PG  G PG   P  PP       T L+     P +P   
Sbjct: 996  GMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPP-----GSTGLRGFIGFPGLPGDQ 1050

Query: 386  GAPGQ-GPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGS 444
            G PG  GP  +S            G    + N      H G   P  E  SP  P   G+
Sbjct: 1051 GEPGSPGPPGFS---------GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGA 1101

Query: 445  PNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGD 499
                      G   S       GS G               G H  P  RG PG+
Sbjct: 1102 SGEQGLPGIQGPRGSPGRPGPPGSSGPPG----------CPGDHGMPGLRGQPGE 1146



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 37/164 (22%), Positives = 51/164 (31%), Gaps = 17/164 (10%)

Query: 338  HPPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSL 397
            H P  L   PGPFG  G+  P  P     +P          P  P   G PG    P + 
Sbjct: 881  HGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPG--------FPGFPGERGKPGAEGCPGAK 932

Query: 398  SEPAPLTLD--TSGKNLTEQNSYSNIP-HEGKHTPLYERSSPINPAQSGSPNHVDSAYFP 454
             EP    +      + L         P  EG+   + ++ +P  P   G         FP
Sbjct: 933  GEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDG------FP 986

Query: 455  GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPG 498
            G      +   +G  G             + G   +P   G PG
Sbjct: 987  GERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPG 1030



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 41/138 (29%), Positives = 45/138 (32%), Gaps = 14/138 (10%)

Query: 858 PPPPALPFYPAS----AYPRHFG----PVPPSQGRGRGFAGVCGFGGPYGETVATGPYRA 909
           P PP LP    S      P   G    P PP      G  G  G  GP G   A G    
Sbjct: 502 PGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVV 561

Query: 910 FRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGP 969
            RV    GH G   G D       Q G        G+    G    H   +  G+G  GP
Sbjct: 562 SRV---KGHKGE-RGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGP 617

Query: 970 F--PLQVVSVGGPARGRP 985
              P +   VG P  G P
Sbjct: 618 LGPPGKAGPVGPPGLGFP 635



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 41/165 (24%), Positives = 53/165 (32%), Gaps = 22/165 (13%)

Query: 344 AARPGPFGMPGMVPPHVPPQM-----LNIP-QTSLQAKPVAPQVPSPGGAPGQGPYPYSL 397
           A  PGP G PG  PP +P +      L +P     +  P  P    P G PG+    +  
Sbjct: 493 ACEPGPMGPPG--PPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGK----HGA 546

Query: 398 SEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSS 457
           S P P      G  +  +       H+G+  P      P  P   G   H      PG  
Sbjct: 547 SGP-PGNKGAKGDMVVSRVK----GHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPG-P 600

Query: 458 TSSSSDNDEGSGGATNHI----SGNKIGWEKTGSHSEPQARGDPG 498
                D   G  G    +        +G    G    P  RG PG
Sbjct: 601 PGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPG 645



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 50/205 (24%), Positives = 62/205 (30%), Gaps = 16/205 (7%)

Query: 877  PVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGG 936
            P PP     RGF G  G  G  GE  + GP     +  A G  G      S        G
Sbjct: 1029 PGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKG 1088

Query: 937  VQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRT 996
                P   G    +G          RG  GR   P      G P      G+   P    
Sbjct: 1089 EPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQP---- 1144

Query: 997  FGRGGRYYGRGYKNQAAIQGRP----PYAASAEEVAKELKSKSGESKSSAMSSDGSLAEN 1052
             G  G    RG +    I G P    P  +        LK + G   +S +   G     
Sbjct: 1145 -GEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPV 1203

Query: 1053 GVMAEEKPAPQMNGSTGDARAPSHS 1077
            G+       P + G  GD  +P  S
Sbjct: 1204 GI-------PGLKGERGDPGSPGIS 1221



 Score = 30.8 bits (68), Expect = 7.5
 Identities = 64/257 (24%), Positives = 81/257 (31%), Gaps = 54/257 (21%)

Query: 858  PPPPALPFY------PASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFR 911
            P PP  P        P      H GP  P +   RG +GV G  GP G+    G      
Sbjct: 744  PGPPGSPGVNGQKGIPGDPAFGHLGP--PGK---RGLSGVPGIKGPRGDPGCPGAEGPAG 798

Query: 912  V---------AAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRR 962
            +             GH G F G         + G   IP Q G        +  + GS  
Sbjct: 799  IPGFLGLKGPKGREGHAG-FPGVPGPPGHSCERGAPGIPGQPG--------LPGYPGSPG 849

Query: 963  GRGGRG-------PFPLQVVSVGG-PARGRPRGVISTPVI-RTFGRGGRYYGRGYKNQAA 1013
              GG+G       P P  +  + G P R    G    P I   FG  G     G K    
Sbjct: 850  APGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRG 909

Query: 1014 IQGRPPYAASAEEVAKE----LKSKSGESKSSAMSSD----------GSLAENGVMA--E 1057
            + G P +     +   E     K + GE   S +  D          G   + G MA   
Sbjct: 910  LPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIIS 969

Query: 1058 EKPAPQMNGSTGDARAP 1074
            +K  P   G  GD   P
Sbjct: 970  QKGTPGEPGPPGDDGFP 986



 Score = 30.4 bits (67), Expect = 9.8
 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 4/60 (6%)

Query: 347  PGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPG----QGPYPYSLSEPAP 402
            PGP G+PG+      P    I     + K   P  P   G PG     G  P  + +P P
Sbjct: 1200 PGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGP 1259


>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
          Length = 386

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 41/145 (28%), Positives = 57/145 (39%), Gaps = 19/145 (13%)

Query: 383 SPGGAP-GQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQ 441
           +P GAP GQG          P    T+ +    Q  Y ++    ++          NP  
Sbjct: 187 NPQGAPWGQG------GNGGPPNFGTNTQGAVAQPGYGSVRASNQN------EGCTNPPP 234

Query: 442 SGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQT 501
           SGS     S+   G S S S  +  GS G  N+  G+  G   +GS S   + G  G  +
Sbjct: 235 SGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSS 290

Query: 502 KAEGSSTASSGSQLAEGK--GSQMG 524
              G S   SGS+ + G   GS  G
Sbjct: 291 GNSGGSRGDSGSESSWGSSTGSSSG 315



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 22/46 (47%), Positives = 27/46 (58%), Gaps = 6/46 (13%)

Query: 455 GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQ 500
           GSST SSS N  GSGG     +G+K G EK G  +E +  G+ G Q
Sbjct: 307 GSSTGSSSGNHGGSGGG----NGHKPGCEKPG--NEARGSGESGIQ 346


>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
          Length = 398

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 41/145 (28%), Positives = 57/145 (39%), Gaps = 19/145 (13%)

Query: 383 SPGGAP-GQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQ 441
           +P GAP GQG          P    T+ +    Q  Y ++    ++          NP  
Sbjct: 187 NPQGAPWGQG------GNGGPPNFGTNTQGAVAQPGYGSVRASNQN------EGCTNPPP 234

Query: 442 SGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQT 501
           SGS     S+   G S S S  +  GS G  N+  G+  G   +GS S   + G  G  +
Sbjct: 235 SGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSS 290

Query: 502 KAEGSSTASSGSQLAEGK--GSQMG 524
              G S   SGS+ + G   GS  G
Sbjct: 291 GNSGGSRGDSGSESSWGSSTGSSSG 315



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 26/65 (40%), Positives = 36/65 (55%), Gaps = 7/65 (10%)

Query: 455 GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQ-TKAEGSSTASSGS 513
           GSST SSS N  GSGG     +G+K G EK G  +E +  G+ G Q  + +G S+    S
Sbjct: 307 GSSTGSSSGNHGGSGGG----NGHKPGCEKPG--NEARGSGESGIQGFRGQGVSSNMRNS 360

Query: 514 QLAEG 518
           + + G
Sbjct: 361 ETSPG 365


>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
          Length = 416

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 41/145 (28%), Positives = 57/145 (39%), Gaps = 19/145 (13%)

Query: 383 SPGGAP-GQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQ 441
           +P GAP GQG          P    T+ +    Q  Y ++    ++          NP  
Sbjct: 187 NPQGAPWGQG------GNGGPPNFGTNTQGAVAQPGYGSVRASNQN------EGCTNPPP 234

Query: 442 SGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQT 501
           SGS     S+   G S S S  +  GS G  N+  G+  G   +GS S   + G  G  +
Sbjct: 235 SGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSS 290

Query: 502 KAEGSSTASSGSQLAEGK--GSQMG 524
              G S   SGS+ + G   GS  G
Sbjct: 291 GNSGGSRGDSGSESSWGSSTGSSSG 315



 Score = 38.5 bits (88), Expect = 0.036
 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 455 GSSTSSSSDNDEGSGGATNHISG-NKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGS 513
           GSST SSS N  GSGG   H  G  K G E  GS  E   +G  G    +     +  G+
Sbjct: 307 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGS-GESGIQGFRGQGVSSNMREISKEGN 365

Query: 514 QLAEGKGSQMGTVQPIPCLLSMPT 537
           +L  G G      +  P + +  T
Sbjct: 366 RLLGGSGDNYRNSETSPGMFNFDT 389


>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
          Length = 476

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 41/145 (28%), Positives = 57/145 (39%), Gaps = 19/145 (13%)

Query: 383 SPGGAP-GQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQ 441
           +P GAP GQG          P    T+ +    Q  Y ++    ++          NP  
Sbjct: 187 NPQGAPWGQG------GNGGPPNFGTNTQGAVAQPGYGSVRASNQN------EGCTNPPP 234

Query: 442 SGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQT 501
           SGS     S+   G S S S  +  GS G  N+  G+  G   +GS S   + G  G  +
Sbjct: 235 SGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSS 290

Query: 502 KAEGSSTASSGSQLAEGK--GSQMG 524
              G S   SGS+ + G   GS  G
Sbjct: 291 GNSGGSRGDSGSESSWGSSTGSSSG 315



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 22/46 (47%), Positives = 27/46 (58%), Gaps = 6/46 (13%)

Query: 455 GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQ 500
           GSST SSS N  GSGG     +G+K G EK G  +E +  G+ G Q
Sbjct: 307 GSSTGSSSGNHGGSGGG----NGHKPGCEKPG--NEARGSGESGIQ 346


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 55/232 (23%), Positives = 73/232 (31%), Gaps = 22/232 (9%)

Query: 856  PFPPPPALPFYPASAYPRHFGPV----PPSQGRGRGFAGVCGFGGPYGETVATGPYRAFR 911
            P PPPP  P  P S        +    P  +    G AG  G  GP G+  A GP  A  
Sbjct: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511

Query: 912  VAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGR-GGRGPF 970
                 G  G        +  K   G+   P + G   + G           G  G RGP 
Sbjct: 512  PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGP- 570

Query: 971  PLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEE---- 1026
                   G P    P G +  P ++  G  G    RG K +  + G P       +    
Sbjct: 571  ------QGPPGLPGPPGRVGAPGLQ--GERGEKGTRGEKGERGLDGFPGKPGDTGQQGRP 622

Query: 1027 ----VAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAP 1074
                VA     K     +      GS+ +   +  E+ AP   G  G    P
Sbjct: 623  GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPP 674



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 49/185 (26%), Positives = 59/185 (31%), Gaps = 29/185 (15%)

Query: 347  PGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPS-PGGAPGQGPYPYSLSEPAPLTL 405
            PGP G  G +     P    +P       P  PQ P  P G PG+   P S  EP P   
Sbjct: 1287 PGPRGESGAMGL---PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP--S 1341

Query: 406  DTSG-KNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDN 464
             T G K    +N    +P       L  R  P  P + G P        PG         
Sbjct: 1342 GTPGQKGSKGENGSPGLPGF-----LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396

Query: 465  DEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQ-TKAEGSSTASSGSQLAEGKGSQM 523
            D G       I G+K           P  +G PGD         T   G Q   G+   +
Sbjct: 1397 DPG-------IKGDK---------GPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV 1440

Query: 524  GTVQP 528
            G   P
Sbjct: 1441 GPPGP 1445



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 44/181 (24%), Positives = 59/181 (32%), Gaps = 40/181 (22%)

Query: 348 GPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGA---PGQGPYPYSLSEPAPLT 404
           GP G+PG++    PP             P  P  P PGG+   PG+  +P     P P  
Sbjct: 702 GPPGIPGLLGLQGPP-----------GPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGP-- 748

Query: 405 LDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDN 464
               GK             +G + P      P  P   G P        PG         
Sbjct: 749 TGPPGK-------------DGPNGP------PGPPGTKGEPGERGEDGLPGKPGLRGEIG 789

Query: 465 DEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQ-TKAEGSSTASSGSQLAEGKGSQM 523
           ++G  G      G K      G+   P  RG+ GDQ  K E       G +  +G+    
Sbjct: 790 EQGLAGR----PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 845

Query: 524 G 524
           G
Sbjct: 846 G 846


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,035,791
Number of Sequences: 37866
Number of extensions: 2803759
Number of successful extensions: 16156
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 492
Number of HSP's that attempted gapping in prelim test: 13112
Number of HSP's gapped (non-prelim): 3390
length of query: 1118
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1005
effective length of database: 13,968,660
effective search space: 14038503300
effective search space used: 14038503300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.