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Search of human proteins with 38787957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38787957 tensin like C1 domain containing phosphatase
isoform 2 [Homo sapiens]
(1409 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38787957 tensin like C1 domain containing phosphatase isoform... 2942 0.0
gi|38787941 tensin like C1 domain containing phosphatase isoform... 2901 0.0
gi|38787970 tensin like C1 domain containing phosphatase isoform... 2695 0.0
gi|66529407 tensin [Homo sapiens] 499 e-141
gi|65288071 tensin 3 [Homo sapiens] 461 e-129
gi|157738639 tensin 4 [Homo sapiens] 301 3e-81
gi|73765544 phosphatase and tensin homolog [Homo sapiens] 129 2e-29
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 120 7e-27
gi|157384971 cyclin G associated kinase [Homo sapiens] 120 9e-27
gi|40549435 transmembrane phosphatase with tensin homology isofo... 108 5e-23
gi|40549433 transmembrane phosphatase with tensin homology isofo... 108 5e-23
gi|109689707 transmembrane phosphatase with tensin homology isof... 108 5e-23
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 100 2e-20
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 100 2e-20
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 100 2e-20
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 97 1e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 79 4e-14
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 79 4e-14
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 79 4e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 78 5e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 77 1e-13
gi|55750053 atrophin-1 [Homo sapiens] 76 2e-13
gi|55750041 atrophin-1 [Homo sapiens] 76 2e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 74 8e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 74 1e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 74 1e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 74 1e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 74 1e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 74 1e-12
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 73 2e-12
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 2942 bits (7627), Expect = 0.0
Identities = 1409/1409 (100%), Positives = 1409/1409 (100%)
Query: 1 MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC 60
MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
Sbjct: 1 MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC 60
Query: 61 RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS 120
RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
Sbjct: 61 RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS 120
Query: 121 LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE 180
LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
Sbjct: 121 LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE 180
Query: 181 KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV 240
KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
Sbjct: 181 KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV 240
Query: 241 IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS 300
IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
Sbjct: 241 IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS 300
Query: 301 PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL 360
PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
Sbjct: 301 PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL 360
Query: 361 KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF 420
KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
Sbjct: 361 KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF 420
Query: 421 VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG 480
VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG
Sbjct: 421 VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG 480
Query: 481 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE 540
SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE
Sbjct: 481 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE 540
Query: 541 LDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYRE 600
LDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYRE
Sbjct: 541 LDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYRE 600
Query: 601 PCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK 660
PCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK
Sbjct: 601 PCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK 660
Query: 661 PATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASE 720
PATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASE
Sbjct: 661 PATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASE 720
Query: 721 AGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH 780
AGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH
Sbjct: 721 AGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH 780
Query: 781 PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQ 840
PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQ
Sbjct: 781 PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQ 840
Query: 841 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 900
SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS
Sbjct: 841 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 900
Query: 901 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL 960
ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL
Sbjct: 901 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL 960
Query: 961 PSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP 1020
PSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP
Sbjct: 961 PSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP 1020
Query: 1021 RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP 1080
RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP
Sbjct: 1021 RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP 1080
Query: 1081 GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFW 1140
GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFW
Sbjct: 1081 GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFW 1140
Query: 1141 YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVR 1200
YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVR
Sbjct: 1141 YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVR 1200
Query: 1201 HFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVP 1260
HFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVP
Sbjct: 1201 HFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVP 1260
Query: 1261 TNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSA 1320
TNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSA
Sbjct: 1261 TNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSA 1320
Query: 1321 QGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENV 1380
QGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENV
Sbjct: 1321 QGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENV 1380
Query: 1381 CHLFAELDPDQPAGAIVTFITKVLLGQRK 1409
CHLFAELDPDQPAGAIVTFITKVLLGQRK
Sbjct: 1381 CHLFAELDPDQPAGAIVTFITKVLLGQRK 1409
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 2901 bits (7521), Expect = 0.0
Identities = 1388/1402 (99%), Positives = 1392/1402 (99%)
Query: 8 ERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVAT 67
+ L + L + R A +PRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVAT
Sbjct: 18 QALGQLLRKESRPRRAMKPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVAT 77
Query: 68 HRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMER 127
HRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMER
Sbjct: 78 HRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMER 137
Query: 128 RWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTR 187
RWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTR
Sbjct: 138 RWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTR 197
Query: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH
Sbjct: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
Query: 248 YSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYV 307
YSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYV
Sbjct: 258 YSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYV 317
Query: 308 LIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVT 367
LIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVT
Sbjct: 318 LIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVT 377
Query: 368 CYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPE 427
CYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPE
Sbjct: 378 CYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPE 437
Query: 428 KIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQ 487
KIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQ
Sbjct: 438 KIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQ 497
Query: 488 RPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGG 547
RPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGG
Sbjct: 498 RPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGG 557
Query: 548 CGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNG 607
CGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNG
Sbjct: 558 CGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNG 617
Query: 608 GYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFG 667
GYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFG
Sbjct: 618 GYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFG 677
Query: 668 YRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLH 727
YRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLH
Sbjct: 678 YRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLH 737
Query: 728 PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV 787
PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV
Sbjct: 738 PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV 797
Query: 788 TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE 847
TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE
Sbjct: 798 TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE 857
Query: 848 IPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSG 907
IPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSG
Sbjct: 858 IPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSG 917
Query: 908 PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE 967
PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE
Sbjct: 918 PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE 977
Query: 968 PLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSP 1027
PLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSP
Sbjct: 978 PLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSP 1037
Query: 1028 DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG 1087
DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG
Sbjct: 1038 DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG 1097
Query: 1088 PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSR 1147
PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSR
Sbjct: 1098 PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSR 1157
Query: 1148 DQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETG 1207
DQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETG
Sbjct: 1158 DQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETG 1217
Query: 1208 PKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAA 1267
PKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAA
Sbjct: 1218 PKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAA 1277
Query: 1268 DLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTD 1327
DLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTD
Sbjct: 1278 DLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTD 1337
Query: 1328 NQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAEL 1387
NQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAEL
Sbjct: 1338 NQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAEL 1397
Query: 1388 DPDQPAGAIVTFITKVLLGQRK 1409
DPDQPAGAIVTFITKVLLGQRK
Sbjct: 1398 DPDQPAGAIVTFITKVLLGQRK 1419
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 2695 bits (6985), Expect = 0.0
Identities = 1285/1285 (100%), Positives = 1285/1285 (100%)
Query: 125 MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 184
MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD
Sbjct: 1 MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 60
Query: 185 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 244
LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA
Sbjct: 61 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 120
Query: 245 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 304
YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL
Sbjct: 121 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 180
Query: 305 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 364
HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV
Sbjct: 181 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 240
Query: 365 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 424
MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS
Sbjct: 241 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 300
Query: 425 SPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYA 484
SPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYA
Sbjct: 301 SPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYA 360
Query: 485 QVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRL 544
QVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRL
Sbjct: 361 QVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRL 420
Query: 545 LGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGV 604
LGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGV
Sbjct: 421 LGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGV 480
Query: 605 PNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATG 664
PNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATG
Sbjct: 481 PNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATG 540
Query: 665 DFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP 724
DFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP
Sbjct: 541 DFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP 600
Query: 725 LLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYP 784
LLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYP
Sbjct: 601 LLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYP 660
Query: 785 ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKL 844
ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKL
Sbjct: 661 ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKL 720
Query: 845 SYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSE 904
SYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSE
Sbjct: 721 SYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSE 780
Query: 905 LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGS 964
LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGS
Sbjct: 781 LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGS 840
Query: 965 GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP 1024
GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP
Sbjct: 841 GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP 900
Query: 1025 DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQ 1084
DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQ
Sbjct: 901 DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQ 960
Query: 1085 QPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPH 1144
QPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPH
Sbjct: 961 QPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPH 1020
Query: 1145 LSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLI 1204
LSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLI
Sbjct: 1021 LSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLI 1080
Query: 1205 ETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMS 1264
ETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMS
Sbjct: 1081 ETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMS 1140
Query: 1265 TAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGIT 1324
TAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGIT
Sbjct: 1141 TAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGIT 1200
Query: 1325 LTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLF 1384
LTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLF
Sbjct: 1201 LTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLF 1260
Query: 1385 AELDPDQPAGAIVTFITKVLLGQRK 1409
AELDPDQPAGAIVTFITKVLLGQRK
Sbjct: 1261 AELDPDQPAGAIVTFITKVLLGQRK 1285
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 499 bits (1285), Expect = e-141
Identities = 367/1022 (35%), Positives = 499/1022 (48%), Gaps = 145/1022 (14%)
Query: 120 SLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLS 179
S+ ME +LDL YVTERI+A +FP+ +E+ R +LRE+A +L+SKH YLLFNLS
Sbjct: 2 SVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLS 61
Query: 180 EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLG 239
E+R D+T+L+ KV +FGWP+LH P L+K+CSICKAM+TWL+ADP +VVVL+ KGN+G++G
Sbjct: 62 ERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIG 121
Query: 240 VIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNS 299
V+++AYMHYS ISA ADQAL M++F EDK+ QPSQRRY+ YFSGLLSGSI+MN+
Sbjct: 122 VVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNN 181
Query: 300 SPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALL 359
PLFLH+V++ +P FE G +PFL+IYQ+MQ VYTSG+Y+I G +CI++EP LL
Sbjct: 182 KPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLL 241
Query: 360 LKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVE 419
LKGD+++ CYHK R R ++FRVQFHTC IH + F K+ LD+A+ D+RFP VE
Sbjct: 242 LKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVE 301
Query: 420 FVFSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPL 478
FVFS PEKI+G N PSVSVDYNT++P +RWDSY+NF+ H +D ++ + HT+GPL
Sbjct: 302 FVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPL 361
Query: 479 DGSPYAQVQRPP---------RQTPPAPSPEP-PPPPMLSVSSDSGHS--STLTTEPAAE 526
DGS YA+V++ T P S P LSVSSDSG+S ST T +
Sbjct: 362 DGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEP 421
Query: 527 SPGRPPPTAA----ERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYP 582
PG TAA E++ELDRLL G G+ +GA T L +P G
Sbjct: 422 VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHL--RSRPAGGSAV------ 473
Query: 583 GHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRR 642
P RH Q + NGG E + +G G + ++
Sbjct: 474 ---PSSGRHVVPAQVH------VNGGALASERETDILDDELPNQDGHSAG-SMGTLSSLD 523
Query: 643 LCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTA 702
+ SEG Y PE P T GL YP
Sbjct: 524 GVTNTSEGGY---PEALSPLTN------------------GLDKSYPM------------ 550
Query: 703 ALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGE 762
E + G P R G PA H APM +P + +
Sbjct: 551 ------------EPMVNGGGYPYESASRAG-------PAHAGHTAPM------RPSYSAQ 585
Query: 763 EGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPG 822
EG G EG HP +P VT S+ PS G S E + P+P
Sbjct: 586 EGLAGYQ----REG--PHPAWPQPVTTSHYAHDPS-----GMFRSQSFSEAEPQLPPAPV 634
Query: 823 AHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWRE 882
++ G + Q ++ + R HL S +AS S +P++
Sbjct: 635 RGGSSREAVQRGLNSWQQQQQQQQQ---PRPPPRQQERAHLESL--VASRPSPQPLAETP 689
Query: 883 GPSGHSTLPRSPRDAP-------------CSASSELSGPSTPLHTSSPVQGKESTRRQDT 929
PS LP PR A E + + PLH S V G +
Sbjct: 690 IPS----LPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLS 745
Query: 930 RSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 989
P S +++ P++Q+ +G P S PEP + + P S S + +
Sbjct: 746 SQPLSGSSRQSH------PLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQ 799
Query: 990 RSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASP 1046
G + +SP ++LP H+P GP+ PP S G P+ S
Sbjct: 800 PCLAGPNQDFHSKSPASSSLPAFLPTTHSP-PGPQQPPASLPGLTAQPLLSPKEATSDPS 858
Query: 1047 EPPQSSPTPAFPLAASYDTNGL-------SQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1099
P+ P L A + G+ ++PP P +R GQ PE S +
Sbjct: 859 RTPEEEPLNLEGLVA-HRVAGVQAREKQPAEPPAPLRRRAASDGQYENQ-SPEATSPRSP 916
Query: 1100 GI 1101
G+
Sbjct: 917 GV 918
Score = 412 bits (1060), Expect = e-115
Identities = 380/1143 (33%), Positives = 504/1143 (44%), Gaps = 257/1143 (22%)
Query: 480 GSPYAQVQRP----PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP--GRPP- 532
GS VQR +Q P PPP +S +S + +P AE+P P
Sbjct: 637 GSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEF 696
Query: 533 PTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHC 592
P AA +QE+++ + + A L + G +PG P S+
Sbjct: 697 PRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVP-------GAWPGASPLSSQPL 749
Query: 593 SCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLY 652
S P GY + G G+P+ AS+E RS S Y
Sbjct: 750 SGSSRQSHPLTQSRSGY-----------IPSGHSLGTPEPAPRASLESVPPGRSYSP--Y 796
Query: 653 PYPPEMGKPATGDFGYRAPGYREVVILED---------------PGL---PALYPCPACE 694
Y P + P DF ++P + PGL P L P A
Sbjct: 797 DYQPCLAGP-NQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATS 855
Query: 695 EKLALPTAA---LYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPD 751
+ P L GL R AG + P P PL + G + P+
Sbjct: 856 DPSRTPEEEPLNLEGLVAHRVAGVQAREK------QPAEPPAPLRRRAASDGQYENQSPE 909
Query: 752 YSCLKPPKAGEEGHEGC-------SYTMCPEGRYGHPGYPALVTYSYG-----GAVPSYC 799
+ + P G C + + P GR P P L +Y G PS
Sbjct: 910 ATSPRSP--GVRSPVQCVSPELALTIALNPGGR---PKEPHLHSYKEAFEEMEGTSPSSP 964
Query: 800 P----------------AYGRVPHSCGS--------------------------PGEGRG 817
P A G PH+ E R
Sbjct: 965 PPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRS 1024
Query: 818 YPSPGAHS----PRAGSISPGSPPYPQSRKLSYEIPTEEG--GDRYPLPGHLASAGPLAS 871
Y A + PRA P S P ++ +EIP G G + P L+++ P+ S
Sbjct: 1025 YVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILS 1084
Query: 872 AESLEPVSWREGPSGHSTLPRSPRDAPCSA---SSELSGPS----------TPLHT---- 914
A+S S+ G S PR+P + S L PS +PL T
Sbjct: 1085 ADSTSVGSFPSGESSDQG-PRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSS 1143
Query: 915 -SSP---VQGKESTRRQDTRS----------PTSAPTQRLSPGEALPPVSQAG------T 954
SSP +Q S+ R+ P S + + G PP G +
Sbjct: 1144 YSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPS 1203
Query: 955 GKAPELPSGSGPEPLAP-------------------SPVSPTF----------------- 978
AP PS S + + P +P SP+
Sbjct: 1204 MAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKV 1263
Query: 979 --PPSSPSDWPQERSPGGHSDG----------ASPRSPV--------PTTLPGL----RH 1014
P SPS R PG H ASP SP + +PG RH
Sbjct: 1264 ATTPGSPS---LGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRH 1320
Query: 1015 APWQGPRGPPD---------SPDG--SPLTPV----PSQMPWL---VASPEPP-----QS 1051
+ G P D S G +P TP P+ P L SP P Q
Sbjct: 1321 VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQG 1380
Query: 1052 SPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLL 1111
SPTPA P G LP + G P G SSP+ G + V+F+ L
Sbjct: 1381 SPTPALPEKRRMSV-GDRAGSLPNYATINGKVSSPVASG---MSSPSGGST--VSFSHTL 1434
Query: 1112 SDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQ 1171
D + + E+++ VKFVQDTSK+WYKP +SR+QAIALLKD++PGAF+IRDSHSF+
Sbjct: 1435 PDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFR 1494
Query: 1172 GAYGLALKVATPPPSA--QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALV 1229
GAYGLA+KV++PPP+ Q KGD +LVRHFLIETGP+GVK+KGCP+EP FGSLSALV
Sbjct: 1495 GAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALV 1554
Query: 1230 SQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESL 1289
QHSI P++LPC L IP++DP +E+ ++ P N + ADLL+QGAAC+VL++ SV+ ESL
Sbjct: 1555 YQHSIIPLALPCKLVIPNRDPTDESKDSSGPAN--STADLLKQGAACNVLFVNSVDMESL 1612
Query: 1290 TGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTD 1349
TGPQA+++A+S L+ P P +VHFKVSAQGITLTDNQRKLFFRRHYP+N++TF D
Sbjct: 1613 TGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLD 1672
Query: 1350 PQDRRWTNPD-GTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLL--G 1406
PQ+R+W + G +K+FGFVA+K GS +N CHLFAELDP+QPA AIV F++KV+L G
Sbjct: 1673 PQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAG 1732
Query: 1407 QRK 1409
Q++
Sbjct: 1733 QKR 1735
Score = 43.9 bits (102), Expect = 0.001
Identities = 98/406 (24%), Positives = 139/406 (34%), Gaps = 63/406 (15%)
Query: 881 REGPSGHSTLPRSPRDAPCSASSELSGPSTP-------LHTSSPVQGKESTRRQDTRSPT 933
R P+G S +P S R A ++G + L P Q S T S
Sbjct: 464 RSRPAGGSAVPSSGRHV-VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSL 522
Query: 934 SAPTQRLSPG--EALPPVSQAGTGKAPELP--SGSGPEPLAPSPVSPTFP----PSSPSD 985
T G EAL P++ P P +G G + S P P PS
Sbjct: 523 DGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSY 582
Query: 986 WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS 1045
QE G +G P P P T H P G S S P Q+P
Sbjct: 583 SAQEGLAGYQREGPHPAWPQPVTTSHYAH----DPSGMFRSQSFSEAEP---QLP----- 630
Query: 1046 PEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHV 1105
P P + + A N Q +++ P P QQ E+A + ++
Sbjct: 631 PAPVRGGSSRE---AVQRGLNSWQQQQQQQQQPRPPPRQQ------ERAHLESL-VASRP 680
Query: 1106 TFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPG--AFL 1163
+ PL +P PE P SQ ++ +T L+ D +P A
Sbjct: 681 SPQPLAETPIPSLPEFPRAASQQEIEQSIETLNM-------------LMLDLEPASAAAP 727
Query: 1164 IRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFG 1223
+ S S GA+ A +++ P S + P+ Q ++ P G + G P
Sbjct: 728 LHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYI----PSGHSL-GTPEPAPRA 782
Query: 1224 SLSALVSQHSISPISLPCCLRIP-----SKDPLEETPEAPVPTNMS 1264
SL ++ S SP CL P SK P + A +PT S
Sbjct: 783 SLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHS 828
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 461 bits (1185), Expect = e-129
Identities = 232/444 (52%), Positives = 310/444 (69%), Gaps = 20/444 (4%)
Query: 125 MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 184
ME LDLTY+TERI+A +FPA E+ + +L+E+ +L+SKH D YL+ NLSEKR+D
Sbjct: 1 MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60
Query: 185 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 244
LT+LNPK+ D GWPELHAPPLDK+C+ICKA E+WL+++ QHVVV++C+G KG++GV++S+
Sbjct: 61 LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
Query: 245 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 304
YMH++ +SA ADQAL M+KF +DKV+ +QPSQ+RY+ + SGLLSGS++MN+SPLFL
Sbjct: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
Query: 305 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 364
H+V++ P F+ G +PFLK+YQ+MQ VYTSG+Y++ P ++CI +EPA LLKGDV
Sbjct: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240
Query: 365 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 424
MV CYHK R R ++FR+QFHT + G L F K+ LD A D+RFP VE VFS+
Sbjct: 241 MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300
Query: 425 SPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPY 483
+PEKI+GS ND V VDYNTT+P +RWDSYEN S DG + HT+GP+DGS Y
Sbjct: 301 TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENL------SADGEVLHTQGPVDGSLY 354
Query: 484 AQVQRPPRQTPPAP-SPEPPPPP--------MLSVSSDSGHSSTLTTEPAAE---SPG-R 530
A+V++ P P P+ P LSVSSDSGHS+ E +PG R
Sbjct: 355 AKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTR 414
Query: 531 PPPTAAERQELDRLLGGCGVASGG 554
+A E+ ELD+LL G G+ G
Sbjct: 415 RGLSAQEKAELDQLLSGFGLEDPG 438
Score = 412 bits (1058), Expect = e-114
Identities = 265/594 (44%), Positives = 337/594 (56%), Gaps = 67/594 (11%)
Query: 858 PLPGHLASAGPLASAESL-EPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTS 915
P H P + E+L V E P G ST+ R+ + S + T + ++
Sbjct: 875 PASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCT-ISSN 933
Query: 916 SPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELP-SGSGPEPLAPSPV 974
P Q +ES+ + + S+P P VS G+G+ P S SPV
Sbjct: 934 GPGQRRESSSSAERQWVESSPK---------PMVSLLGSGRPTGSPLSAEFSGTRKDSPV 984
Query: 975 SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTP 1034
FPPS E HS S P + P Q G +P GS L P
Sbjct: 985 LSCFPPS-------ELQAPFHSHELSLAEPPDSLAPPSS----QAFLGFGTAPVGSGLPP 1033
Query: 1035 VPSQMPWLVASPEPPQSSPTPAFPLAA---------------------SYDTNGLS---- 1069
+ L+A+ +SPTP+ PL A S+ + GL
Sbjct: 1034 -EEDLGALLANSHG--ASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGV 1090
Query: 1070 ----QPPLPEKRHLPGPGQQPGPWGPEQA--SSPARGISHHVTFAPLLSD-NVPQTPEPP 1122
QPPLPEK+ + G P + SSP G + + F +L D + P
Sbjct: 1091 TLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
Query: 1123 TQESQSN----VKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLAL 1178
+S + VKFVQDTSKFWYK +SR+QAIA+LKDK+PG+F++RDSHSF+GAYGLA+
Sbjct: 1151 LPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAM 1210
Query: 1179 KVATPPPSAQPWK---GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSIS 1235
KVATPPPS GD +LVRHFLIE PKGV++KGC +EPYFGSL+ALV QHSI+
Sbjct: 1211 KVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSIT 1270
Query: 1236 PISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1295
P++LPC L IP +DPLEE E+ T ++AA+LL+QGAAC+V YL SVE ESLTG QA+
Sbjct: 1271 PLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAI 1330
Query: 1296 ARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRW 1355
+A S L P P VVHFKVSAQGITLTDNQRKLFFRRHYPVNS+ F + DPQDR+W
Sbjct: 1331 QKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKW 1390
Query: 1356 TNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK 1409
DG +SK+FGFVA+K GS +NVCHLFAE DP+QPA AIV F++KV++G K
Sbjct: 1391 IK-DGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPK 1443
Score = 37.0 bits (84), Expect = 0.13
Identities = 57/210 (27%), Positives = 79/210 (37%), Gaps = 31/210 (14%)
Query: 832 SPGSPPYP------QSRKLSYEI-PTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 884
SPGSP Q +L E+ PT E P+P H+ + G A+ S+ P S G
Sbjct: 687 SPGSPTLDIDQSIEQLNRLILELDPTFE-----PIPTHMNALGSQANG-SVSPDSVGGGL 740
Query: 885 SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 944
S LP + + + S PL K S + D + P + + G+
Sbjct: 741 RASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR---KLSLGQYDNDAGGQLPFSKCAWGK 797
Query: 945 ALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWP---QERSPGGHSDGASP 1001
A G AP LP P P +P+ V T P P D S ++P
Sbjct: 798 A-------GVDYAPNLP----PFP-SPADVKETMTPGYPQDLDIIDGRILSSKESMCSTP 845
Query: 1002 RSPVPTTLPGLRHAPWQGPRGPPDSPDGSP 1031
PV P ++ A P PP+ P SP
Sbjct: 846 AFPVSPETPYVKTALRHPPFSPPEPPLSSP 875
Score = 35.4 bits (80), Expect = 0.39
Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 20/179 (11%)
Query: 803 GRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGH 862
G P P G G P GS P P P RK S + G
Sbjct: 530 GEDPQGTLVPDLGLGMDGPYERERTFGSREP-KQPQPLLRKPSVSAQMQAYGQ-----SS 583
Query: 863 LASAGPLASAESLEPVSWREGPSGHSTL-PRSPRDAPCSASSELSGPSTPLHTSSPVQGK 921
++ + + + + P G + L R P D P ++ P TP +S +
Sbjct: 584 YSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTS---SR 640
Query: 922 ESTRRQDTRSPTSAPTQRLSPGEALP---PVSQAGTGKAPELPSGSGPEPLAPSPVSPT 977
+ +R P TQ+ SP +A P Q G PEL +G PSP SPT
Sbjct: 641 VAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTG-------PSPGSPT 692
>gi|157738639 tensin 4 [Homo sapiens]
Length = 715
Score = 301 bits (771), Expect = 3e-81
Identities = 195/492 (39%), Positives = 262/492 (53%), Gaps = 38/492 (7%)
Query: 931 SPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPT----------FPP 980
S S+P SP A P + + G AP+ GS L+ SPVS
Sbjct: 238 SKASSPHGLGSPLVASPRLEKRLGGLAPQ--RGSRISVLSASPVSDVSYMFGSSQSLLHS 295
Query: 981 SSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMP 1040
S+ S RS ++ +S + + R + +Q PR P + G P TP +
Sbjct: 296 SNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTM-GQPRTPHSPPLA 354
Query: 1041 WLVASPEPPQSSPTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQ--QPGPWGPEQASSP 1097
AS PP + + P+ NG +P + PG QPG P
Sbjct: 355 KEHASSCPPSITNSMVDIPIVL---INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPA 411
Query: 1098 ARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDK 1157
R S ++ AP + PE P ++ Q +KFV DTSK+W+KP+++R+QAI LL+ +
Sbjct: 412 TRSNSQTLSDAPFTT-----CPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKE 466
Query: 1158 DPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCP 1217
+PGAF+IRDS S++G++GLALKV P SAQ G+ L+RHFLIE+ KGV +KG
Sbjct: 467 EPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGAD 526
Query: 1218 SEPYFGSLSALVSQHSISPISLPCCLRIPSK-----DPLEETPEAPVPTNMSTAADLLRQ 1272
EPYFGSLSA V QHSI ++LPC L IP + D ++ ++P A ++
Sbjct: 527 EEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSP--------ASCQKK 578
Query: 1273 GAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKL 1332
A C LYL+SV E+LTG AV +A S PTP VVHFKV+ QGITLTD QRK+
Sbjct: 579 SAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKV 638
Query: 1333 FFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQP 1392
FFRRHYP+ ++ F DP+ R+W S IFGFVAK P ENVCHLFAE D QP
Sbjct: 639 FFRRHYPLTTLRFCGMDPEQRKW-QKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQP 697
Query: 1393 AGAIVTFITKVL 1404
A ++ +T +L
Sbjct: 698 ASQVIGLVTALL 709
>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
Length = 403
Score = 129 bits (325), Expect = 2e-29
Identities = 83/279 (29%), Positives = 138/279 (49%), Gaps = 11/279 (3%)
Query: 126 ERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRH-D 184
E +DLDLTY+ I+A FPA E +R ++ ++ L SKH++ Y ++NL +RH D
Sbjct: 18 EDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYD 77
Query: 185 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 244
+ N +V + + + + P L+ + C+ ++ WLS D HV ++CK KG+ GV++ A
Sbjct: 78 TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICA 137
Query: 245 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 304
Y+ + A +AL + + K T PSQRRY+ Y+S LL + L
Sbjct: 138 YLLHRGKFLKAQEALDFYGEVRTRDKKGVT--IPSQRRYVYYYSYLLKNHLDYRPVALLF 195
Query: 305 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQ---LCISLEPALLLK 361
H ++ +P F GT P + Q +Y+S +GP ++ + L +
Sbjct: 196 HKMMFETIPMFSGGT-CNPQFVVCQLKVKIYSSN----SGPTRREDKFMYFEFPQPLPVC 250
Query: 362 GDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPK 400
GD+ V +HK + + +F +T I GP+ T K
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
sapiens]
Length = 913
Score = 120 bits (302), Expect = 7e-27
Identities = 93/353 (26%), Positives = 166/353 (47%), Gaps = 28/353 (7%)
Query: 130 DLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLN 189
DLD TYVT RI+ +FP + R + ++ L S+H D Y ++NLS K + + +
Sbjct: 63 DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122
Query: 190 PKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYS 249
+V + WP AP L L ++C+ M WL +P++V V++C + ++V A +
Sbjct: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182
Query: 250 KISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGS-IRMNSSPLFLHYVL 308
+ + A+ L + + L PS RRY+ Y LL+ R + PL + +
Sbjct: 183 NLYSTPGPAIRLLYAK-----RPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSIT 237
Query: 309 IPMLPAF-EPGTGFQPFLKIYQSMQLVYT--SGVYHIAGPGPQQLCISLEPALLLKGDVM 365
+ +P F + G +P+ + +Y+ + + Q I + + ++GDV+
Sbjct: 238 VSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVV 297
Query: 366 VTCYHK----GGR---GTDRTLVFRVQFHT--CTIHGPQLTFPKDQLDEAWTDERFP--F 414
V+ YH G R T +F++QFHT + L F K +LD E++P F
Sbjct: 298 VSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLF 357
Query: 415 QASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSV 467
Q +++ V +K+ TP + + D N P++ + S+ Q H+D++
Sbjct: 358 QVTLD-VELQPHDKVIDLTPPWEHYCTKDVN---PSILFSSH----QEHQDTL 402
Score = 38.5 bits (88), Expect = 0.046
Identities = 69/326 (21%), Positives = 104/326 (31%), Gaps = 62/326 (19%)
Query: 813 GEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASA 872
G G G P P +PP P+ L + + + P A P ++
Sbjct: 468 GNANGDKPHGVKKPSKKQQEPAAPPPPEDVDL-LGLEGSAMSNSFSPP-----AAPPTNS 521
Query: 873 ESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 932
E L + G +G P A S ++ PS P T +ST R+ S
Sbjct: 522 ELLSDLFGGGGAAG-------PTQAGQSGVEDVFHPSGPAST-------QSTPRRSATST 567
Query: 933 TSAPTQRLSPGEALPP----------------VSQAGTGKAPELPSGSGPEPLAPSPVSP 976
+++PT R+ G P ++ + P L P P + +P
Sbjct: 568 SASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTP 627
Query: 977 --TFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPD------ 1028
P W PGG G+ + PT G H + P + D
Sbjct: 628 AVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT---GSSHGT-PTHQSKPQTLDPFADLG 683
Query: 1029 --GSPLTPVPSQMPWLVASPEPPQSSPTPAF--PLAASYDTNGLSQPPLPEKRHLPGPGQ 1084
GS P + PP SSP A P+ + G P
Sbjct: 684 TLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQP---------- 733
Query: 1085 QPGPWGPEQASSPARGISHHVTFAPL 1110
QP P SSP +++V+F+ +
Sbjct: 734 QPKPQPSMPHSSPQNRPNYNVSFSAM 759
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 120 bits (301), Expect = 9e-27
Identities = 84/305 (27%), Positives = 156/305 (51%), Gaps = 20/305 (6%)
Query: 130 DLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLN 189
DLD++Y+T RI +FPA E + ++ ++ L SKH Y ++NLS + + +R +
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFH 466
Query: 190 PKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYS 249
+V + GW AP L L +IC+ M WL D ++V V++C + V V +++ +
Sbjct: 467 NRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFC 526
Query: 250 KISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGS-IRMNSSPLFLHYVL 308
++ + A+ A+ +M+ + + PS +RYI Y +++ I +S P+ + V+
Sbjct: 527 RLFSTAEAAVYMFSMK-----RCPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVV 581
Query: 309 IPMLPAF-EPGTGFQPFLKIYQSMQLV-YTSGVYHIAGPGPQQLCISLEP-ALLLKGDVM 365
+ +P F + +G +PF ++Y + V TS Y + ++ P + ++GDV+
Sbjct: 582 MTPVPLFSKQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVL 641
Query: 366 VTCYHK----GGRGTDRTL---VFRVQFHTCTI--HGPQLTFPKDQLDEAWTDERFP--F 414
+ YH GGR + +F++QFHT + + + F K LD E++P F
Sbjct: 642 IVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLF 701
Query: 415 QASVE 419
Q ++E
Sbjct: 702 QVNLE 706
Score = 35.0 bits (79), Expect = 0.51
Identities = 63/237 (26%), Positives = 88/237 (37%), Gaps = 33/237 (13%)
Query: 876 EPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSA 935
+P S + +G + P D+ SS S LHT + KE+ + S +
Sbjct: 757 QPGSTAQYDAGAGSPEAEPTDSDSPPSSSADA-SRFLHTLDWQEEKEAETGAENASSKES 815
Query: 936 PTQRLSPGEALPPVSQAGTGKAPE-LPSGSGPEP--LAPSPVSPTF------PPSSPSDW 986
+ + + + G+ + E + PEP LA V P P
Sbjct: 816 ESALMEDRDESEVSDEGGSPISSEGQEPRADPEPPGLAAGLVQQDLVFEVETPAVLPEPV 875
Query: 987 PQERSP---GGHSD-GASPRSPVPTTLPGLRHAPWQGPR------GPPDSPDGSPLTPVP 1036
PQE G HS+ GA P P P AP GPP++ P +
Sbjct: 876 PQEDGVDLLGLHSEVGAGPAVP-----PQACKAPSSNTDLLSCLLGPPEAASQGPPEDLL 930
Query: 1037 SQMPWLVASPEPP---QSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1090
S+ P L+ASP PP QS+P P AA D G P LP + P P +G
Sbjct: 931 SEDPLLLASPAPPLSVQSTPRGGPPAAA--DPFG---PLLPSSGNNSQPCSNPDLFG 982
Score = 32.7 bits (73), Expect = 2.5
Identities = 62/263 (23%), Positives = 85/263 (32%), Gaps = 50/263 (19%)
Query: 860 PGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQ 919
P L S PL A P+S + P G P +S S P S+P
Sbjct: 926 PEDLLSEDPLLLASPAPPLSVQSTPRGGPPAAADPFGPLLPSSGNNSQPC-----SNPDL 980
Query: 920 GKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFP 979
E P S P+ +P PP A +LP P + S +P
Sbjct: 981 FGEFLNSDSVTVPPSFPSAHSAP----PPSCSADFLHLGDLPGE--PSKMTASSSNPDLL 1034
Query: 980 PSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQM 1039
+ W + AS +P P T GP SP G P P SQ
Sbjct: 1035 GGWAA-WTET--------AASAVAPTPAT------------EGPLFSPGGQP-APCGSQA 1072
Query: 1040 PWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1099
W + +P P L ++GL P G PG + P+ A++P
Sbjct: 1073 SWTKSQ------NPDPFADLGDL--SSGLQGSPA---------GFPPGGFIPKTATTPKG 1115
Query: 1100 GISHHVTFAPLLSDNVPQTPEPP 1122
S + P + P +PP
Sbjct: 1116 SSSWQTSRPPAQGASWPPQAKPP 1138
Score = 31.2 bits (69), Expect = 7.4
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 6/98 (6%)
Query: 469 GSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP 528
G + T GS Q RPP Q P P+ PPP ++S + A E
Sbjct: 1104 GFIPKTATTPKGSSSWQTSRPPAQGASWP-PQAKPPPKACTQPRPNYASNFSVIGAREER 1162
Query: 529 GRPPPTAAER-----QELDRLLGGCGVASGGRGAGRET 561
G P+ A++ + + LL G +S G +T
Sbjct: 1163 GVRAPSFAQKPKVSENDFEDLLSNQGFSSRSDKKGPKT 1200
>gi|40549435 transmembrane phosphatase with tensin homology isoform
gamma [Homo sapiens]
Length = 513
Score = 108 bits (269), Expect = 5e-23
Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)
Query: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
+DLDLTYVTERI+A +FP+ + +R ++E+ L KHR+ Y ++NL SE+ +D
Sbjct: 197 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 256
Query: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
+ +V + + P L ++ K + W++ D +++V ++CKG + G +V A++
Sbjct: 257 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 316
Query: 248 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 301
S+I + A ++L R+ DK +E PSQ+RY++YF+ + N P
Sbjct: 317 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 373
Query: 302 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 356
LF+ + +I +P + Q ++ ++ ++ L S + +I ++ I +
Sbjct: 374 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 430
Query: 357 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 413
L L DV V ++ F HT I +L PK++LD + +P
Sbjct: 431 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 490
Query: 414 FQASVEFVFS---SSPEKIKGS 432
+VE +F +S + + GS
Sbjct: 491 SDFAVEILFGEKMTSSDVVAGS 512
>gi|40549433 transmembrane phosphatase with tensin homology isoform
beta [Homo sapiens]
Length = 533
Score = 108 bits (269), Expect = 5e-23
Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)
Query: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
+DLDLTYVTERI+A +FP+ + +R ++E+ L KHR+ Y ++NL SE+ +D
Sbjct: 217 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 276
Query: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
+ +V + + P L ++ K + W++ D +++V ++CKG + G +V A++
Sbjct: 277 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 336
Query: 248 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 301
S+I + A ++L R+ DK +E PSQ+RY++YF+ + N P
Sbjct: 337 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 393
Query: 302 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 356
LF+ + +I +P + Q ++ ++ ++ L S + +I ++ I +
Sbjct: 394 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 450
Query: 357 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 413
L L DV V ++ F HT I +L PK++LD + +P
Sbjct: 451 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 510
Query: 414 FQASVEFVFS---SSPEKIKGS 432
+VE +F +S + + GS
Sbjct: 511 SDFAVEILFGEKMTSSDVVAGS 532
>gi|109689707 transmembrane phosphatase with tensin homology isoform
alpha [Homo sapiens]
Length = 551
Score = 108 bits (269), Expect = 5e-23
Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)
Query: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
+DLDLTYVTERI+A +FP+ + +R ++E+ L KHR+ Y ++NL SE+ +D
Sbjct: 235 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 294
Query: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
+ +V + + P L ++ K + W++ D +++V ++CKG + G +V A++
Sbjct: 295 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 354
Query: 248 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 301
S+I + A ++L R+ DK +E PSQ+RY++YF+ + N P
Sbjct: 355 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 411
Query: 302 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 356
LF+ + +I +P + Q ++ ++ ++ L S + +I ++ I +
Sbjct: 412 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 468
Query: 357 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 413
L L DV V ++ F HT I +L PK++LD + +P
Sbjct: 469 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 528
Query: 414 FQASVEFVFS---SSPEKIKGS 432
+VE +F +S + + GS
Sbjct: 529 SDFAVEILFGEKMTSSDVVAGS 550
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 99.8 bits (247), Expect = 2e-20
Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)
Query: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
+DLDLTYVTERI+A +FP+ + +R + E+ L KHR+ Y ++NL SE+ +D
Sbjct: 106 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 165
Query: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
+ +V + + P L ++ K + W++ D +++V ++CKG KG+ G +V A +
Sbjct: 166 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 225
Query: 248 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 301
S+I A+++L R K +K PSQ RY+ YF+ + N P
Sbjct: 226 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 284
Query: 302 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 358
LF+ +I + Q ++ ++ S L S ++ I ++ I++
Sbjct: 285 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 341
Query: 359 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 413
L DV V + F F+T I +L P+++LD +AW + +P
Sbjct: 342 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 399
Query: 414 FQASVEFVF 422
+ +VE +F
Sbjct: 400 PEFAVEILF 408
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 99.8 bits (247), Expect = 2e-20
Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)
Query: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
+DLDLTYVTERI+A +FP+ + +R + E+ L KHR+ Y ++NL SE+ +D
Sbjct: 217 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 276
Query: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
+ +V + + P L ++ K + W++ D +++V ++CKG KG+ G +V A +
Sbjct: 277 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 336
Query: 248 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 301
S+I A+++L R K +K PSQ RY+ YF+ + N P
Sbjct: 337 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 395
Query: 302 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 358
LF+ +I + Q ++ ++ S L S ++ I ++ I++
Sbjct: 396 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 452
Query: 359 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 413
L DV V + F F+T I +L P+++LD +AW + +P
Sbjct: 453 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 510
Query: 414 FQASVEFVF 422
+ +VE +F
Sbjct: 511 PEFAVEILF 519
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 99.8 bits (247), Expect = 2e-20
Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)
Query: 129 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 187
+DLDLTYVTERI+A +FP+ + +R + E+ L KHR+ Y ++NL SE+ +D
Sbjct: 140 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 199
Query: 188 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247
+ +V + + P L ++ K + W++ D +++V ++CKG KG+ G +V A +
Sbjct: 200 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 259
Query: 248 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 301
S+I A+++L R K +K PSQ RY+ YF+ + N P
Sbjct: 260 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 318
Query: 302 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 358
LF+ +I + Q ++ ++ S L S ++ I ++ I++
Sbjct: 319 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 375
Query: 359 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 413
L DV V + F F+T I +L P+++LD +AW + +P
Sbjct: 376 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 433
Query: 414 FQASVEFVF 422
+ +VE +F
Sbjct: 434 PEFAVEILF 442
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 97.1 bits (240), Expect = 1e-19
Identities = 109/387 (28%), Positives = 152/387 (39%), Gaps = 39/387 (10%)
Query: 779 GHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGY-PSP-GAHSPRAGSISPGSP 836
G G+ G P Y PA+ P S GSPG Y PSP GA SP S SP SP
Sbjct: 1542 GAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSP---SYSPTSP 1598
Query: 837 PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLA-SAESLEPVSWREGPSGHSTLPRSPR 895
Y P GG P + ++ + ++ S P S P+ S P SP
Sbjct: 1599 AYE---------PRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPS 1649
Query: 896 DAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTG 955
+P S S P++P ++ + ++ SP+ +PT S P S
Sbjct: 1650 YSPTSPS---YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPS 1705
Query: 956 KAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSP--VPTTLPGLR 1013
+P PS S P + SP SP++ P+SPS P S S SP SP PT+
Sbjct: 1706 YSPTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSP 1764
Query: 1014 HAPWQGPRGP---PDSPDGSPLTP--VPSQMPWLVASPEPPQSSP-----TPAF-PLAAS 1062
+P P P P SP+ SP +P P+ + SP SSP +P + P + S
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPS 1824
Query: 1063 YDTNGLSQPPLPEKRHLPGPGQQPG-----PWGPEQASSPARGISHHVTFAPLLSDNVPQ 1117
Y + S P K P P P P+ + + + ++P P
Sbjct: 1825 YSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPT 1884
Query: 1118 TPE-PPTQESQSNVKFVQDTSKFWYKP 1143
TP+ PT + S V + Y P
Sbjct: 1885 TPKYSPTSPTYSPTSPVYTPTSPKYSP 1911
Score = 80.5 bits (197), Expect = 1e-14
Identities = 110/404 (27%), Positives = 147/404 (36%), Gaps = 44/404 (10%)
Query: 750 PDYSCLKPPKAGEEGHEGCSYTMCPE-GRYGHPGY----PALVTYSYGGAVPSYCPAYGR 804
P YS P G G G S P G P Y PA S GG P P+Y
Sbjct: 1559 PGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQ-SPSYSP 1617
Query: 805 VPHSCG------SPGEGRGYPSPGAHSPRAGSISPGSPPY-PQSRKLSYEIPTEEGGDRY 857
S SP P+ ++SP + S SP SP Y P S S P+
Sbjct: 1618 TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS----- 1672
Query: 858 PLPGHLASAGPLAS--AESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPS----TP 911
P + P S + S P S P+ S P SP +P S S + PS +P
Sbjct: 1673 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1732
Query: 912 LHTSSPVQGKESTRRQDTRSPTSAPTQ-RLSP-GEALPPVSQAGTGKAPEL-PSGSGPEP 968
++ + ++ SP PT SP + P S T +P P+ P
Sbjct: 1733 SYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSP 1792
Query: 969 LAPS--PVSPTFPPSSPSDWPQERSPGGHSDGASPRSP--VPTTLPGLRHAPWQGPRGP- 1023
+PS P SP++ PSSP PQ + S SP SP PT+ +P P P
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPE 1852
Query: 1024 --PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAF-PLAASYDTNGLSQPPLPEKRHLP 1080
P SP SP +P S + P S TP + P + +Y P K
Sbjct: 1853 YTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPT 1912
Query: 1081 GPGQQP-----GPWGPEQASSPARGISHHVTFAPLLSDNVPQTP 1119
P P P P + + +G T++P P +P
Sbjct: 1913 SPTYSPTSPKYSPTSPTYSPTSPKG----STYSPTSPGYSPTSP 1952
Score = 62.4 bits (150), Expect = 3e-09
Identities = 92/327 (28%), Positives = 123/327 (37%), Gaps = 57/327 (17%)
Query: 843 KLSYEIPTEEGGDRYPLPGHLASAGP----LASAES----LEPVS--WREGPS------- 885
K EIPT +PG L +AGP SA S + P W +G +
Sbjct: 1481 KYGMEIPTN-------IPG-LGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWS 1532
Query: 886 ---GHSTLPRSPRDAPCSASSELSGPSTPLHTS-SPVQGKESTRRQDTRSPTSAPTQRLS 941
G P + +P SA+S+ SG S + SP G SP + S
Sbjct: 1533 PSVGSGMTPGAAGFSP-SAASDASGFSPGYSPAWSPTPGSPG-------SPGPSSPYIPS 1584
Query: 942 PGEALPP-VSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGAS 1000
PG A+ P S P P G P+ + SP SP++ P+SPS P + S S
Sbjct: 1585 PGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYS 1644
Query: 1001 PRSP--VPTTLPGLRHAPWQGPRGP---PDSPDGSPLTP-----VPSQMPWLVA-SPEPP 1049
P SP PT+ +P P P P SP SP +P PS P + SP P
Sbjct: 1645 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1704
Query: 1050 QSSPT-PAF-PLAASYDTNGLSQPPLPEKRHLPGPGQQP-----GPWGPEQASSPARGIS 1102
SPT P++ P + SY S P P P P P +
Sbjct: 1705 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSP 1764
Query: 1103 HHVTFAPLLSDNVPQTPE-PPTQESQS 1128
+++P + P +P PT S S
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYS 1791
Score = 62.4 bits (150), Expect = 3e-09
Identities = 112/465 (24%), Positives = 153/465 (32%), Gaps = 57/465 (12%)
Query: 547 GCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGH--RPGLSR-HCSCRQGYREPCG 603
G G+ G G A D + G P PG PG S + G P
Sbjct: 1536 GSGMTPGAAGFSPSAA--SDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSY 1593
Query: 604 VPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK--P 661
P Y P GGY Y+ S S S Y P P
Sbjct: 1594 SPTSPAYEPRSP--------GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSP 1645
Query: 662 ATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEA 721
+ + +P Y P P+ P PT+ Y + +
Sbjct: 1646 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS----PTSPSYSPTSPSYSPTSPSYSP 1701
Query: 722 GKPLLHPVRPGHP--LPLLLPACGHHHAPMPDYSCLKP---PKAGEEGHEGCSYTMCPEG 776
P P P + P P + P YS P P + +YT P
Sbjct: 1702 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYT--PTS 1759
Query: 777 RYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSP 836
P P SY P+Y P SP P+ ++SP + S SP SP
Sbjct: 1760 PSYSPTSP-----SYSPTSPNYTPTSPNY-----SPTSPSYSPTSPSYSPTSPSYSPSSP 1809
Query: 837 PY-PQSRKLSYEIPT--EEGGDRYPLPGHLASAGPLASAESLE--PVSWREGPSGHSTLP 891
Y PQS + P+ P P S S E P S + P+ P
Sbjct: 1810 RYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSP 1869
Query: 892 RSPRDAPCSASSELS----GPSTPLHT-SSPVQGKESTRRQDTRSPTSAPTQRLSPGEAL 946
SP+ +P S + + P++P ++ +SPV S + T SPT +PT
Sbjct: 1870 TSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPT-SPTYSPTS-------- 1920
Query: 947 PPVSQAGTGKAPELPSGSGPEPLAP--SPVSPTFPPSSPSDWPQE 989
P S +P P GS P +P SP SPT+ +SP+ P +
Sbjct: 1921 PKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDD 1965
Score = 59.7 bits (143), Expect = 2e-08
Identities = 95/380 (25%), Positives = 134/380 (35%), Gaps = 36/380 (9%)
Query: 646 SLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALY 705
++S P P + G + ++P Y P P+ P PT+ Y
Sbjct: 1588 AMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYS----PTSPSY 1643
Query: 706 GLRLEREAGEGWASEAGKPLLHPVRPGHP--LPLLLPACGHHHAPMPDYSCLKP---PKA 760
+ + P P P + P P + P YS P P +
Sbjct: 1644 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1703
Query: 761 GEEGHEGCSYT-MCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYP 819
SY+ P P Y + SY PSY P SP P
Sbjct: 1704 PSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPNY-----SPTSPNYTP 1757
Query: 820 SPGAHSPRAGSISPGSPPY-PQSRKLSYEIPTEE--GGDRYPLPGHLASAGPLASAES-- 874
+ ++SP + S SP SP Y P S S P+ P + + P + +S
Sbjct: 1758 TSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPT 1817
Query: 875 LEPVSWREGPSGHSTLPRSPRDAPCSASSELSGP----STPLHTSSPVQGKESTRRQDTR 930
P S PS S P SP+ P S S S P ++P ++ + + ++ +
Sbjct: 1818 YTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPT 1877
Query: 931 SPTSAPTQ-RLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 989
SPT +PT + SP P S P P S P SP SP + P+SP+ P
Sbjct: 1878 SPTYSPTTPKYSPTS--PTYSPTSPVYTPTSPKYSPTSPTY-SPTSPKYSPTSPTYSP-- 1932
Query: 990 RSPGGH-----SDGASPRSP 1004
SP G S G SP SP
Sbjct: 1933 TSPKGSTYSPTSPGYSPTSP 1952
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 78.6 bits (192), Expect = 4e-14
Identities = 174/674 (25%), Positives = 223/674 (33%), Gaps = 83/674 (12%)
Query: 475 RGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG----R 530
R P +P RPP SP PPPP + G + + +P AE G
Sbjct: 15 RTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 531 PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGG-GPHLGVYPGHRPGLS 589
P +A R R G S A R A E P P PG G +
Sbjct: 69 TIPESAPRAGPTRSAG----TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124
Query: 590 RHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYE---GSPQGYAEASMEKRRLCRS 646
R Q + +R L+ G G G +M +R
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 647 LSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYG 706
GL P P +P G R + P PA + P+A G
Sbjct: 185 TEVGL-PRPAPSARPRPPTEGPRKS------VSSASEHSTTEPSPAARRR---PSA---G 231
Query: 707 LRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPD-YSCLKPPKAGEEGH 765
L+R A +S A PL P R G A H P P L+PP+
Sbjct: 232 GGLQRPASRSLSSSA-TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 766 EGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCP-AYGRVPHSCGSPGEGRGYPSPGAH 824
+ G L T S A+ S P PHS + P P A
Sbjct: 291 DAAP-------ALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ-LATPLPLAP 342
Query: 825 SPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 884
SP +PP Q+ P + P A+ L S L P++ P
Sbjct: 343 P------SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLA-TPPP 394
Query: 885 SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKEST---RRQDTRSPTSAPTQRLS 941
L P AP S + S P +PL T SP + P S P Q
Sbjct: 395 QAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
Query: 942 PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP 1001
A PPVS + T + PS + P PL P P PP SPS P ++P + A P
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAPPPLA--APP 509
Query: 1002 ---RSPVPTTLPGLRHAPWQGPRGPPDS-PDGSPLTPVPSQMPWLVASPEPPQSSPTPAF 1057
P P P L P Q PP S P +P +P S +P + PPQ+ P A
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLATPPPQAPPVLAA 568
Query: 1058 PLAASYDTNGLSQPPL-PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVP 1116
PL L PP P L P + P P GP+ + S R L P
Sbjct: 569 PL--------LQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPR----------LTLALAP 609
Query: 1117 QTPEPPTQESQSNV 1130
P PP++ S +
Sbjct: 610 GPPPPPSRSPSSTL 623
Score = 69.3 bits (168), Expect = 2e-11
Identities = 111/425 (26%), Positives = 155/425 (36%), Gaps = 51/425 (12%)
Query: 800 PAYGRVPHSCGSP-GEGRGYPSPGAHSPRAG---SISPGSP-----PYPQSRKLSYEIPT 850
PA R + G+ G R PS P G S+S S P P +R+ P+
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR----PS 229
Query: 851 EEGGDRYPLPGHLAS-AGPLASAESLEPVSWREGPSGHST--LPRSPRDAPCSASSELSG 907
GG + P L+S A PL+S R GPS T P P L
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPA-------RSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 908 PST--PLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVS-----QAGTGKAPEL 960
P P ++P G S+ T SP++A + P P S Q T
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
Query: 961 PSGSGPEPLAPSPVSPTFPPS-SPSDWPQERSPGGHSDGASP-----RSPVPTTLPGLRH 1014
PS S P L P P PPS + + HS SP +P P P L
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
Query: 1015 APWQGPRGPPDSPDGSPL-TPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPL 1073
P Q P PP SP SPL TP P L SP P+ P+ A + + PP+
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPV 460
Query: 1074 PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFV 1133
P P P ++P + +P +S + P+ P + ++
Sbjct: 461 -------SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 1134 QDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGD 1193
+ + P L+ AL P +F + S + ++ +ATPPP A P
Sbjct: 514 KPPPQA--PPALATPPLQAL--PSPPASFPGQAPFSPSASLPMS-PLATPPPQAPPVLAA 568
Query: 1194 PVEQL 1198
P+ Q+
Sbjct: 569 PLLQV 573
Score = 63.5 bits (153), Expect = 1e-09
Identities = 173/671 (25%), Positives = 221/671 (32%), Gaps = 122/671 (18%)
Query: 469 GSLTHTRGPLDGSPYAQVQRPPRQTP-------PAPSPEPPPP---PMLSVSSDSGHSST 518
G+ T GP G+P + R R PAPS P PP P SVSS S HS+T
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 519 LTTEPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQ--PTVGGGP 576
P P A R GG R L + P+ G P
Sbjct: 219 -----------EPSPAARRRPSA----GGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 577 HLGVYPGH-RP-GLSRHCSCRQGYREPCGVPNGGYYRPE-GTLERRRLAYGGYEGSPQGY 633
+P +P GL Q R P P P G L LA + Q
Sbjct: 264 RAPAHPSQPKPKGL-------QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316
Query: 634 AEASMEKRRLCRSLSEGLY-PYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPA 692
A ++ SL+ L P P P+ AP + + P PA P A
Sbjct: 317 APPTLPATPHSSSLTCQLATPLPLAPPSPS-------APPSLQTL----PSPPATPPSQA 365
Query: 693 CEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVR---PGHPLPLLLPACGHHHAP- 748
L PT + S P L P+ P P L LP +P
Sbjct: 366 TTS-LGSPTL------------QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
Query: 749 -MPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAY---GR 804
P S L P P + P P + A P P+ +
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAP---FSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469
Query: 805 VPHSCGSPGEGRGYPSPGAHSPRAGSISPG--SPPYPQSRKLSYEIPTEEGGDRYPLPGH 862
P S +P + PSP A P + S +P +PP + L P + P
Sbjct: 470 APPSLAAPPL-QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 528
Query: 863 LASAGPLASAESLEPVSWREGPSGHSTLPRSP-RDAPCSASSELSGPSTPLHTSSPVQGK 921
A P AS P S PS ++LP SP P A L+ P + S P
Sbjct: 529 QALPSPPASFPGQAPFS----PS--ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582
Query: 922 -ESTRRQDTRSP---TSAP--TQRLSPGEALPPV-SQAGTGKAPELPSGSGPEPLAPSPV 974
++ RR T P S P T L+PG PP S + T P+L S
Sbjct: 583 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS---------- 632
Query: 975 SPTFPPSSPSDWPQERS--PGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL 1032
SS + P+E G GA+ P L A W PP + G+P
Sbjct: 633 ------SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
Query: 1033 TPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNG-LSQPPLPEKRHLPGPGQQPGPWGP 1091
P +PW PP + P A L Y+T G S P P PG PG G
Sbjct: 687 AP----LPW------PPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGG 733
Query: 1092 EQASSPARGIS 1102
+ A+ G S
Sbjct: 734 KAAAGAGAGAS 744
Score = 50.4 bits (119), Expect = 1e-05
Identities = 128/501 (25%), Positives = 168/501 (33%), Gaps = 79/501 (15%)
Query: 839 PQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESL--EPVSWREGPSGHSTLPRSPRD 896
P +R P G R P P A+ L +A ++ +P++ R G G +T+P S
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES--- 73
Query: 897 APCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP-----PVSQ 951
AP + + +G S+ S P R ++ + P SPG A P+ Q
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS--SPGRASGTTRPGPLGQ 131
Query: 952 AGT----------GKAPELPSGSGPEPLAPSPVS-PTFPPSSPSDWPQERSPGGHSDGAS 1000
G GKA E P S A S PT P +PS RS ++
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGTEVGL 189
Query: 1001 PRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLT---PVPSQMPWLVASPEPP--QSSPTP 1055
PR P P+ P P +GPR S T P + P + P +S +
Sbjct: 190 PR-PAPSARP---RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 1056 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1115
A PL++ S P P QP P G QA P + AP L
Sbjct: 246 ATPLSSP----ARSGPSARGTPRAPAHPSQPKPKGL-QALRPPQVTPPRKDAAPALG--- 297
Query: 1116 PQTPEPPTQESQSNVKFVQDTSKFWYKPH---LSRDQAIAL-LKDKDPGAFLIRDSHSFQ 1171
P + P S S Q PH L+ A L L P A S Q
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA-----PPSLQ 352
Query: 1172 GAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQ 1231
L ATPP A G P Q FL PS P +S
Sbjct: 353 T---LPSPPATPPSQATTSLGSPTLQATHSFL-------------PSPP--------LSP 388
Query: 1232 HSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTG 1291
+ P P L +P PL+ P P +S A Q ++L
Sbjct: 389 LATPPPQAPPALALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445
Query: 1292 PQAVARAS-SAALSCSPRPTP 1311
P A S A+ SP TP
Sbjct: 446 PPVQAPFSPPASPPVSPSATP 466
Score = 41.6 bits (96), Expect = 0.005
Identities = 64/256 (25%), Positives = 81/256 (31%), Gaps = 29/256 (11%)
Query: 796 PSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAG-SISPGSPPYPQS-----RKLSYEIP 849
P P P P +P SP A +SP + P PQ+ L P
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575
Query: 850 TEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPC-SASSELSGP 908
+ P + GP S GP L P P S SS LSGP
Sbjct: 576 SPPASPTLQAPRRPPTPGPDTSVS---------GPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 909 STPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEP 968
H+SS E R D+ P P L A + P P P
Sbjct: 627 DLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685
Query: 969 LAPSPVSPTFPPSS--------PSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP 1020
AP P P P S ++ P+ +P + GA P P T G + A G
Sbjct: 686 GAPLPWPPATGPGSADGLCTIYETEGPESATP---APGALDPGPSPGTSGG-KAAAGAGA 741
Query: 1021 RGPPDSPDGSPLTPVP 1036
SP + L +P
Sbjct: 742 GASSRSPKQARLGELP 757
Score = 31.2 bits (69), Expect = 7.4
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 6/129 (4%)
Query: 951 QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1010
+A G A P+ P L P P PP P P G + GA R P+
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLG-AAGAVGRKPLAERAG 63
Query: 1011 GLRHA--PWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL 1068
G+ A P PR P G+ S+ P P + T P+++ +G
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 1069 SQP-PLPEK 1076
++P PL +K
Sbjct: 124 TRPGPLGQK 132
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 78.6 bits (192), Expect = 4e-14
Identities = 95/346 (27%), Positives = 117/346 (33%), Gaps = 51/346 (14%)
Query: 716 GWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPE 775
G S + KP P PG +P+ GH P PP + G + P+
Sbjct: 132 GGRSTSAKPFSPPSGPGR---FPVPSPGHRSGPPEPQRNRMPPPRPDVGSK-------PD 181
Query: 776 GRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGS 835
S VPS PH+ GSP P PG PR S P
Sbjct: 182 --------------SIPPPVPSTPRPIQSSPHNRGSP------PVPGG--PRQPSPGPTP 219
Query: 836 PPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPR 895
PP+P +R + GG P L+S+ P ++ L P R P
Sbjct: 220 PPFPGNRGTALG-----GGSIRQSP--LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Query: 896 DAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTG 955
+ P S E P P + PV P P R PG P S +G
Sbjct: 273 NRP-SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR--PGPPPLPPSSSGND 329
Query: 956 KAPELP------SGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVP--- 1006
+ P LP S S P +P P PP S P R P G S P PV
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG 389
Query: 1007 TTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1052
+T L P R DSP P P+P P A P PP S+
Sbjct: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435
Score = 57.4 bits (137), Expect = 1e-07
Identities = 105/409 (25%), Positives = 138/409 (33%), Gaps = 79/409 (19%)
Query: 806 PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLAS 865
P G+ G G G+ G G GS GG P G L
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGS----------------FGGGGPPGLGGLFQ 105
Query: 866 AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKES-- 923
AG L + R+ SG S P P +++ S PS P P G S
Sbjct: 106 AG----MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP 161
Query: 924 TRRQDTRSPTSAPTQRLSPGEALPPVS------QAGTGKAPELPSGSGPEPLAPSPVSPT 977
Q R P P P PPV Q+ P GP +P P P
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221
Query: 978 FPPSSPS---DWPQERSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRG--------- 1022
FP + + +SP S S R P+P T + P P G
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281
Query: 1023 -PPDSPDGS----PLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKR 1077
PP P + P TP PS P PP P P ++S + P LP++
Sbjct: 282 VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND---ETPRLPQRN 338
Query: 1078 --------HLPGPGQQPGPWGP---EQASSPAR---GISHHVTFAPLLSDN------VPQ 1117
LP PG+ GP P E+ P R G S + P +S N +P
Sbjct: 339 LSLSSSTPPLPSPGRS-GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 1118 TPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRD 1166
TP+ P S+S V D+ + +P L D+ A P + IR+
Sbjct: 398 TPQLP---SRSGV----DSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439
Score = 35.8 bits (81), Expect = 0.30
Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 20/99 (20%)
Query: 465 DSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPM-----------------L 507
DS+ + T P+ SP+ + P P PSP P PPP L
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
Query: 508 SVSSDSGHSSTLTTEPAA---ESPGRPPPTAAERQELDR 543
S SS + L P+ + P PPP R + R
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279
Score = 33.5 bits (75), Expect = 1.5
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 10/71 (14%)
Query: 477 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSD------SGHSSTLTTEPAAESPGR 530
P P A Q PP PP+ P PPP P S +D + S ++ P SPGR
Sbjct: 295 PSTPRPSASSQAPPPPPPPS-RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353
Query: 531 P---PPTAAER 538
PP +ER
Sbjct: 354 SGPLPPPPSER 364
Score = 32.0 bits (71), Expect = 4.3
Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 491 RQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP--PPTAAERQELDRL 544
R+ P P P+ PP+ S S S P PG P PP+++ E RL
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Score = 32.0 bits (71), Expect = 4.3
Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 476 GPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEP------AAESP- 528
GPL P + P R P P PPPPP VS + S L P +SP
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPP---VSRNGSTSRALPATPQLPSRSGVDSPR 411
Query: 529 -GRPPPTAAER 538
G PP +R
Sbjct: 412 SGPRPPLPPDR 422
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 78.6 bits (192), Expect = 4e-14
Identities = 95/346 (27%), Positives = 117/346 (33%), Gaps = 51/346 (14%)
Query: 716 GWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPE 775
G S + KP P PG +P+ GH P PP + G + P+
Sbjct: 132 GGRSTSAKPFSPPSGPGR---FPVPSPGHRSGPPEPQRNRMPPPRPDVGSK-------PD 181
Query: 776 GRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGS 835
S VPS PH+ GSP P PG PR S P
Sbjct: 182 --------------SIPPPVPSTPRPIQSSPHNRGSP------PVPGG--PRQPSPGPTP 219
Query: 836 PPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPR 895
PP+P +R + GG P L+S+ P ++ L P R P
Sbjct: 220 PPFPGNRGTALG-----GGSIRQSP--LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Query: 896 DAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTG 955
+ P S E P P + PV P P R PG P S +G
Sbjct: 273 NRP-SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR--PGPPPLPPSSSGND 329
Query: 956 KAPELP------SGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVP--- 1006
+ P LP S S P +P P PP S P R P G S P PV
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG 389
Query: 1007 TTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1052
+T L P R DSP P P+P P A P PP S+
Sbjct: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435
Score = 57.4 bits (137), Expect = 1e-07
Identities = 105/409 (25%), Positives = 138/409 (33%), Gaps = 79/409 (19%)
Query: 806 PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLAS 865
P G+ G G G+ G G GS GG P G L
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGS----------------FGGGGPPGLGGLFQ 105
Query: 866 AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKES-- 923
AG L + R+ SG S P P +++ S PS P P G S
Sbjct: 106 AG----MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP 161
Query: 924 TRRQDTRSPTSAPTQRLSPGEALPPVS------QAGTGKAPELPSGSGPEPLAPSPVSPT 977
Q R P P P PPV Q+ P GP +P P P
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221
Query: 978 FPPSSPS---DWPQERSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRG--------- 1022
FP + + +SP S S R P+P T + P P G
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281
Query: 1023 -PPDSPDGS----PLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKR 1077
PP P + P TP PS P PP P P ++S + P LP++
Sbjct: 282 VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND---ETPRLPQRN 338
Query: 1078 --------HLPGPGQQPGPWGP---EQASSPAR---GISHHVTFAPLLSDN------VPQ 1117
LP PG+ GP P E+ P R G S + P +S N +P
Sbjct: 339 LSLSSSTPPLPSPGRS-GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 1118 TPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRD 1166
TP+ P S+S V D+ + +P L D+ A P + IR+
Sbjct: 398 TPQLP---SRSGV----DSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439
Score = 35.8 bits (81), Expect = 0.30
Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 20/99 (20%)
Query: 465 DSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPM-----------------L 507
DS+ + T P+ SP+ + P P PSP P PPP L
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
Query: 508 SVSSDSGHSSTLTTEPAA---ESPGRPPPTAAERQELDR 543
S SS + L P+ + P PPP R + R
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279
Score = 33.5 bits (75), Expect = 1.5
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 10/71 (14%)
Query: 477 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSD------SGHSSTLTTEPAAESPGR 530
P P A Q PP PP+ P PPP P S +D + S ++ P SPGR
Sbjct: 295 PSTPRPSASSQAPPPPPPPS-RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353
Query: 531 P---PPTAAER 538
PP +ER
Sbjct: 354 SGPLPPPPSER 364
Score = 32.0 bits (71), Expect = 4.3
Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 491 RQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP--PPTAAERQELDRL 544
R+ P P P+ PP+ S S S P PG P PP+++ E RL
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Score = 32.0 bits (71), Expect = 4.3
Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 476 GPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEP------AAESP- 528
GPL P + P R P P PPPPP VS + S L P +SP
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPP---VSRNGSTSRALPATPQLPSRSGVDSPR 411
Query: 529 -GRPPPTAAER 538
G PP +R
Sbjct: 412 SGPRPPLPPDR 422
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 78.2 bits (191), Expect = 5e-14
Identities = 167/672 (24%), Positives = 217/672 (32%), Gaps = 118/672 (17%)
Query: 475 RGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG----R 530
R P +P RPP SP PPPP + G + + +P AE G
Sbjct: 15 RTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 531 PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSR 590
P +A R R + GRG + P P PG G +R
Sbjct: 69 TIPESAPRAGPTRT---SRPPASGRG---------ERAPPAKNTSPGPVSSPGRASGTTR 116
Query: 591 HCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYE---GSPQGYAEASMEKRRLCRSL 647
Q + +R L+ G G G +M +R
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 648 SEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGL 707
GL P P +P G R + P PA + P+A G
Sbjct: 177 EVGL-PRPAPSARPRPPTEGPRKS------VSSASEHSTTEPSPAARRR---PSA---GG 223
Query: 708 RLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPD-YSCLKPPKAGEEGHE 766
L+R A +S A PL P R G A H P P L+PP+
Sbjct: 224 GLQRPASRSLSSSA-TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ------- 275
Query: 767 GCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSP 826
+ P + P L + PS P S +P + PSP A P
Sbjct: 276 -----VTPPRKDAAPALGPLSSSPLATPSPS-------APPSPSAPPSLQTLPSPPATPP 323
Query: 827 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSG 886
+ S GSP + P PLA+ P
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLS----------------PLATPP----------PQA 357
Query: 887 HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKEST---RRQDTRSPTSAPTQRLSPG 943
L P AP S + S P +PL T SP + P S P Q
Sbjct: 358 PPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Query: 944 EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP-- 1001
A PPVS + T + PS + P PL P P PP SPS P ++P + A P
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAPPPLA--APPLQ 472
Query: 1002 -RSPVPTTLPGLRHAPWQGPRGPPDS-PDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPL 1059
P P P L P Q PP S P +P +P S +P + PPQ+ P A PL
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLATPPPQAPPVLAAPL 531
Query: 1060 AASYDTNGLSQPPL-PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQT 1118
L PP P L P + P P GP+ + S R L P
Sbjct: 532 --------LQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPR----------LTLALAPGP 572
Query: 1119 PEPPTQESQSNV 1130
P PP++ S +
Sbjct: 573 PPPPSRSPSSTL 584
Score = 73.2 bits (178), Expect = 2e-12
Identities = 116/458 (25%), Positives = 158/458 (34%), Gaps = 78/458 (17%)
Query: 800 PAYGRVPHSCGSPGEGRGYPSPG--------------------AHSPRAGSISPG----- 834
PA P SPG G PG +P+ ++S G
Sbjct: 96 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 155
Query: 835 SPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSP 894
S P P + + + G LP SA P E P S HST SP
Sbjct: 156 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG--PRKSVSSASEHSTTEPSP 213
Query: 895 --RDAPCS-------ASSELSGPSTPLHTSSPVQGKESTRRQDTR-----SPTSAPTQRL 940
R P + AS LS +TPL SSP + S R P Q L
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPL--SSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 941 SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPS-----SPSDWPQERSPGG- 994
P + PP A P L S P +P SP+ PPS SP P ++
Sbjct: 272 RPPQVTPPRKDAAPALGP-LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330
Query: 995 --------HSDGASP-----RSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL-TPVPSQMP 1040
HS SP +P P P L P Q P PP SP SPL TP P
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390
Query: 1041 WLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARG 1100
L SP P+ P+ A + + PP+ P P P ++P
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPV-------SPSATPPSQAPPSLAAPPLQ 441
Query: 1101 ISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPG 1160
+ +P +S + P+ P + ++ + + P L+ AL P
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA--PPALATPPLQAL--PSPPA 497
Query: 1161 AFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQL 1198
+F + S + ++ +ATPPP A P P+ Q+
Sbjct: 498 SFPGQAPFSPSASLPMS-PLATPPPQAPPVLAAPLLQV 534
Score = 69.7 bits (169), Expect = 2e-11
Identities = 168/663 (25%), Positives = 213/663 (32%), Gaps = 136/663 (20%)
Query: 469 GSLTHTRGPLDGSPYAQVQRPPRQTP-------PAPSPEPPPP---PMLSVSSDSGHSST 518
G+ T GP G+P + R R PAPS P PP P SVSS S HS
Sbjct: 150 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-- 207
Query: 519 LTTEPAAESPGRPPPTAAERQELDRLLGGCG--VASGGRGAGRETAILDDEEQPTVGGGP 576
TTEP+ + RP ++ R L ++S R P+ G P
Sbjct: 208 -TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG------------PSARGTP 254
Query: 577 HLGVYPGH-RP-GLSRHCSCRQGYREPCGVPNGGYYRPE-GTLERRRLAYGGYEGSPQGY 633
+P +P GL Q R P P P G L LA P
Sbjct: 255 RAPAHPSQPKPKGL-------QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307
Query: 634 AEASMEKRRLCRSLSEGLYPYPPEMG-KPATGDFGYRAPGYREVVILEDPGLPALYPCPA 692
A S++ P PP AT G + P P P P
Sbjct: 308 APPSLQT-----------LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356
Query: 693 CEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDY 752
LALP + S P L P+ P P A H P
Sbjct: 357 APPALALPPL------------QAPPSPPASPPLSPLAT--PSPQAPNALAVHLLQAPFS 402
Query: 753 SCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSP 812
PP + + P P + PS P P P
Sbjct: 403 PPPSPPV---------------QAPFSPPASPPVS--------PSATPPSQAPPSLAAPP 439
Query: 813 GEGRGYPSPGAHSPRAGSISPG--SPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLA 870
+ PSP A P + S +P +PP + L P + P A P A
Sbjct: 440 LQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 871 SAESLEPVSWREGPSGHSTLPRSP-RDAPCSASSELSGPSTPLHTSSPVQGK-ESTRRQD 928
S P S PS ++LP SP P A L+ P + S P ++ RR
Sbjct: 498 SFPGQAPFS----PS--ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551
Query: 929 TRSP---TSAP--TQRLSPGEALPPV-SQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSS 982
T P S P T L+PG PP S + T P+L S SS
Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS----------------SS 595
Query: 983 PSDWPQERS--PGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMP 1040
+ P+E G GA+ P L A W PP + G+P P +P
Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP----LP 651
Query: 1041 WLVASPEPPQSSPTPAFPLAASYDTNG-LSQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1099
W PP + P A L Y+T G S P P PG PG G + A+
Sbjct: 652 W------PPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGGKAAAGAGA 702
Query: 1100 GIS 1102
G S
Sbjct: 703 GAS 705
Score = 41.6 bits (96), Expect = 0.005
Identities = 64/256 (25%), Positives = 81/256 (31%), Gaps = 29/256 (11%)
Query: 796 PSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAG-SISPGSPPYPQS-----RKLSYEIP 849
P P P P +P SP A +SP + P PQ+ L P
Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 536
Query: 850 TEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPC-SASSELSGP 908
+ P + GP S GP L P P S SS LSGP
Sbjct: 537 SPPASPTLQAPRRPPTPGPDTSVS---------GPRLTLALAPGPPPPPSRSPSSTLSGP 587
Query: 909 STPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEP 968
H+SS E R D+ P P L A + P P P
Sbjct: 588 DLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 646
Query: 969 LAPSPVSPTFPPSS--------PSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP 1020
AP P P P S ++ P+ +P + GA P P T G + A G
Sbjct: 647 GAPLPWPPATGPGSADGLCTIYETEGPESATP---APGALDPGPSPGTSGG-KAAAGAGA 702
Query: 1021 RGPPDSPDGSPLTPVP 1036
SP + L +P
Sbjct: 703 GASSRSPKQARLGELP 718
Score = 31.6 bits (70), Expect = 5.6
Identities = 88/385 (22%), Positives = 130/385 (33%), Gaps = 45/385 (11%)
Query: 951 QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1010
+A G A P+ P L P P PP P P G + GA R P+
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLG-AAGAVGRKPLAERAG 63
Query: 1011 GL------RHAPWQGP---RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLA- 1060
G+ AP GP PP S G P + P V+SP + P PL
Sbjct: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQ 122
Query: 1061 -----ASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQAS-SPARGISHHV--TFAPLLS 1112
++ +T + KR G + GP + SPA T L
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182
Query: 1113 DNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQG 1172
P PPT+ + +V + H + + + A + G L R + +
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASE--------HSTTEPSPAARRRPSAGGGLQRPAS--RS 232
Query: 1173 AYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCP--------SEPYFGS 1224
A +++P S +G P + H + PKG++ P + P G
Sbjct: 233 LSSSATPLSSPARSGPSARGTP--RAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGP 289
Query: 1225 LSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSV 1284
LS+ + SP + P PS L P P P+ +T+ A S L +
Sbjct: 290 LSS-SPLATPSPSAPPSPSAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPL 347
Query: 1285 ETESLTGPQAVARASSAALSCSPRP 1309
+ PQA + L P P
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSP 372
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 77.0 bits (188), Expect = 1e-13
Identities = 130/474 (27%), Positives = 169/474 (35%), Gaps = 72/474 (15%)
Query: 679 LEDPGLPALYP--CPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLP 736
L P PA P P + L+LP + L S A PL P+ HPL
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL---------SPAVSPLSSPLTI-HPLQ 490
Query: 737 LLLPACGHHHA---------PMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV 787
L H P+ S L PP S T P P L
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP---ASLTTPPLENLPSLAPPPLQ 547
Query: 788 TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE 847
T S P P P C +P + PSP P S +PP PQ+
Sbjct: 548 TAS----APLTTPHLETPP--CPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALAS 600
Query: 848 IPTEEGGDRYPLPGHLASAGPLASAE-SLEPVSWREGPSGHSTLPRSPRDAPCSASSE-- 904
P + G P LA+ P A +L P+ + PS ++ P SP P +
Sbjct: 601 PPLQ--GLPSPPLSPLATPPPQAPPXLALPPL--QAPPSPPASPPLSPLATPSPQAPNAL 656
Query: 905 ----LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKA-PE 959
L P +P S PVQ S SP++ P + P A PP+ + A P
Sbjct: 657 AVHLLQAPFSP-PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715
Query: 960 LPSGSGPEPLAPSPVSPT---FPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAP 1016
+ + P P AP P++ PPS P+ P S +P P P L P
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA----------TPPPRVPPLLAAPP 765
Query: 1017 WQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP--AFPLAASYDTNGLSQPPLP 1074
Q P PP S SPL P Q P +A+P P Q+ P+P +FP Q P
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPPASFP----------GQAPFS 814
Query: 1075 EKRHLP-GPGQQPGPWGPEQASSPARGISHHVTFAPLL-SDNVPQTPEPPTQES 1126
LP P P P P ++P + +P L + P TP P T S
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868
Score = 75.9 bits (185), Expect = 3e-13
Identities = 111/389 (28%), Positives = 145/389 (37%), Gaps = 50/389 (12%)
Query: 820 SPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVS 879
S +HSP+A S PP L+ P + PL + SL P
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLA--------PPSLQTPPASLTTPPLENLPSLAPPP 545
Query: 880 WREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQR 939
+ S T P PC A L P +PL T P T P AP
Sbjct: 546 LQTA-SAPLTTPHL-ETPPCPAPCPLQAPPSPLTTPPP-----ETPSSIATPPPQAPPAL 598
Query: 940 LSP---GEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 996
SP G PP+S T P+ P PL P P PP SP P ++P +
Sbjct: 599 ASPPLQGLPSPPLSPLAT-PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657
Query: 997 DGA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPT 1054
+P SP P+ P Q P PP SP SP PSQ P +A+P P Q P+
Sbjct: 658 VHLLQAPFSPPPSP-------PVQAPFSPPASPPVSPSATPPSQAPPSLAAP-PLQVPPS 709
Query: 1055 PAF--PLAASYDTNGLSQPPL--PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPL 1110
P P++ S + PPL P + P P P P P A+ P R PL
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-PMSPS-ATPPPR-------VPPL 760
Query: 1111 LSDNVPQTP-EPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHS 1169
L+ Q P PP S + + P L+ AL P +F + S
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAP----PALATPPLQAL--PSPPASFPGQAPFS 814
Query: 1170 FQGAYGLALKVATPPPSAQPWKGDPVEQL 1198
+ ++ +ATPPP A P P+ Q+
Sbjct: 815 PSASLPMS-PLATPPPQAPPVLAAPLLQV 842
Score = 66.2 bits (160), Expect = 2e-10
Identities = 124/497 (24%), Positives = 158/497 (31%), Gaps = 120/497 (24%)
Query: 830 SISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHST 889
S SP + P P K P + PLP L + PLA+ L P S P T
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAAT--PLPATLPPSPPLATPLPLAPPS-PSAPPSLQT 356
Query: 890 LPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPV 949
LP P P A P T+ P+Q S + T P P SP PP
Sbjct: 357 LPSPPATPPSQAP--------PSMTTPPMQAPPSLQ---TIPPIQVPHSLTSPSLQAPPS 405
Query: 950 SQAGTGKAPELPSGS------------GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 997
A + GS P S SP+ P S+P D
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD------------ 453
Query: 998 GASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS--PEPPQSSPTP 1055
SP P +LP P Q P SP SPLT P Q +AS P+ P SS
Sbjct: 454 --SPPLQAPLSLPA--SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS--- 506
Query: 1056 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1115
L PPL + L P Q P +T PL +N+
Sbjct: 507 ------------LIMPPLETQSSLAPPSLQTPPAS--------------LTTPPL--ENL 538
Query: 1116 PQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYG 1175
P PP Q + + + PHL A + P + L +
Sbjct: 539 PSLAPPPLQTASAPLT----------TPHLETPPCPAPCPLQAPPSPLTTPPPETPSS-- 586
Query: 1176 LALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSIS 1235
+ATPPP A P P ++G PS P +S +
Sbjct: 587 ----IATPPPQAPPALASP-----------------PLQGLPSPP--------LSPLATP 617
Query: 1236 PISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1295
P P L +P PL+ P P +S A Q ++L P
Sbjct: 618 PPQAPPXLALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 1296 ARAS-SAALSCSPRPTP 1311
A S A+ SP TP
Sbjct: 675 APFSPPASPPVSPSATP 691
Score = 62.0 bits (149), Expect = 4e-09
Identities = 81/286 (28%), Positives = 105/286 (36%), Gaps = 22/286 (7%)
Query: 800 PAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPG-------SPPYPQSRKLSYEIPTEE 852
PA P SPG G PG + IS + P+ LS +
Sbjct: 105 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164
Query: 853 GGDRYPLPGHLASAGPLAS-AESLEPVSWREGPSGHSTLP-RSPRDAPCSASSELSGPST 910
G P PG + A S A E R PS P PR + SAS + +
Sbjct: 165 SG---PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221
Query: 911 PLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGP---E 967
P P G +R +RS +S+ T SP + P S GT +AP PS P +
Sbjct: 222 PAARRRPSAGG-GLQRPASRSLSSSATPLSSPARSGP--SARGTPRAPAHPSQPKPKGLQ 278
Query: 968 PLAPSPVSPTFPPSSPSDWPQERSP-GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDS 1026
L P V+P ++P+ P SP S + PVP P P PP +
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
Query: 1027 PDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPP 1072
P PS P L P PP + P+ A P S T + PP
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP---SMTTPPMQAPP 381
Score = 57.8 bits (138), Expect = 7e-08
Identities = 81/299 (27%), Positives = 101/299 (33%), Gaps = 39/299 (13%)
Query: 819 PSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPV 878
PSP A P +SP + P P+ L P + P P PLA P
Sbjct: 739 PSPPASPP----MSPSATPPPRVPPLLAAPPLQVP----PSPPASLPMSPLAKPPPQAPP 790
Query: 879 SWREGPSGHSTLPRS--PRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAP 936
+ P P + P AP S S+ L P +PL T P Q + P S P
Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPP-QAPPVLAAPLLQVPPSPP 847
Query: 937 TQRLSPGEALPPVSQAGTG-KAPELPSGSGPEPLAPSPVSPTFPPSSP---------SDW 986
PP T P L P P P SP+ S P +
Sbjct: 848 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907
Query: 987 PQERS--PGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVA 1044
P+E G GA+ P L A W PP + G+P P +PW
Sbjct: 908 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP----LPW--- 960
Query: 1045 SPEPPQSSPTPAFPLAASYDTNG-LSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGIS 1102
PP + P A L Y+T G S P P PG PG G + A+ G S
Sbjct: 961 ---PPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGGKAAAGAGAGAS 1013
Score = 45.1 bits (105), Expect = 5e-04
Identities = 120/506 (23%), Positives = 170/506 (33%), Gaps = 115/506 (22%)
Query: 839 PQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESL--EPVSWREGPSGHSTLPRSPRD 896
P +R P G R P P A+ L +A ++ +P++ R G G +T+P S
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES--- 73
Query: 897 APCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP-----PVSQ 951
AP + + +G S+ S P R ++ + P SPG A P+ Q
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS--SPGRASGTTRPGPLGQ 131
Query: 952 AGT----------GKAPELP------SGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGH 995
G GKA E P +G+ + P+P +P
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP------------------- 172
Query: 996 SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP 1055
S + RS T GL PR P PS A P PP P
Sbjct: 173 SPAMARRSRAAGTEVGL-------PR------------PAPS------ARPRPPTEGPRK 207
Query: 1056 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1115
+ A+ + T P P R P G SS A +S P +
Sbjct: 208 SVSSASEHSTT----EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP----SA 259
Query: 1116 PQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYG 1175
TP P SQ K +Q L Q KD P + S
Sbjct: 260 RGTPRAPAHPSQPKPKGLQ---------ALRPPQVTPPRKDAAPALGPLSSS-------- 302
Query: 1176 LALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIK-----GCPSEPYFGSLSALVS 1230
+ATP PS + P L T P + PS SL L S
Sbjct: 303 ---PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Query: 1231 QHSISPISLPCCLRIP---SKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVE-T 1286
+ P P + P + L+ P VP ++++ + A S L L+S++ T
Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS----LQAPPSPLALSSLQAT 415
Query: 1287 ESLTGPQAVARASSAALSCSPRPTPA 1312
SL P +A+ + L+ SPR T A
Sbjct: 416 TSLGSP--TLQATHSFLTMSPRQTQA 439
Score = 43.9 bits (102), Expect = 0.001
Identities = 68/271 (25%), Positives = 86/271 (31%), Gaps = 29/271 (10%)
Query: 781 PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAG-SISPGSPPYP 839
P PA + S P P P P +P SP A +SP + P P
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 840 QS-----RKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSP 894
Q+ L P+ P + GP S GP L P
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS---------GPRLTLALAPGP 880
Query: 895 RDAPC-SASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAG 953
P S SS LSGP H+SS E R D+ P P L A
Sbjct: 881 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAA 939
Query: 954 TGKAPELPSGSGPEPLAPSPVSPTFPPSS--------PSDWPQERSPGGHSDGASPRSPV 1005
+ P P P AP P P P S ++ P+ +P + GA P
Sbjct: 940 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP---APGALDPGPS 996
Query: 1006 PTTLPGLRHAPWQGPRGPPDSPDGSPLTPVP 1036
P T G + A G SP + L +P
Sbjct: 997 PGTSGG-KAAAGAGAGASSRSPKQARLGELP 1026
Score = 38.5 bits (88), Expect = 0.046
Identities = 29/73 (39%), Positives = 34/73 (46%), Gaps = 13/73 (17%)
Query: 469 GSLTHTRGPLDGSPYAQVQRPPRQTP-------PAPSPEPPPP---PMLSVSSDSGHSST 518
G+ T GP G+P + R R PAPS P PP P SVSS S HS
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-- 216
Query: 519 LTTEPAAESPGRP 531
TTEP+ + RP
Sbjct: 217 -TTEPSPAARRRP 228
Score = 35.0 bits (79), Expect = 0.51
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 5/65 (7%)
Query: 477 PLDGSPYAQVQRPPRQTPPAPSPEPPP--PPMLS---VSSDSGHSSTLTTEPAAESPGRP 531
PL P PP P +PS PPP PP+L+ + ++L P A+ P +
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Query: 532 PPTAA 536
PP A
Sbjct: 789 PPALA 793
Score = 33.1 bits (74), Expect = 1.9
Identities = 32/95 (33%), Positives = 38/95 (40%), Gaps = 19/95 (20%)
Query: 481 SPYAQV-QRPPRQTPP----------APSPEPPPPPMLSVSSD------SGHSSTLTTEP 523
SP Q +RPP P A +P PPPPP S SS +GHSS+ T+ P
Sbjct: 849 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908
Query: 524 --AAESPGRPPPTAAERQELDRLLGGCGVASGGRG 556
P AA D L C A+ RG
Sbjct: 909 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943
Score = 32.7 bits (73), Expect = 2.5
Identities = 16/48 (33%), Positives = 23/48 (47%)
Query: 489 PPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAA 536
PP Q PP+P PP P+ + S + ++ + A SP PP A
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675
Score = 32.0 bits (71), Expect = 4.3
Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 482 PYAQVQRPPRQTPPAPSPEP-----PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAA 536
P + + +PP Q PPA + P PP + S++L P A P + PP A
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
Score = 31.6 bits (70), Expect = 5.6
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 481 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAA 536
SP A P TPP +P P P L V S ++ P+A P R PP A
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS--PSATPPPRVPPLLA 762
Score = 31.2 bits (69), Expect = 7.4
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 6/129 (4%)
Query: 951 QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1010
+A G A P+ P L P P PP P P G + GA R P+
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLG-AAGAVGRKPLAERAG 63
Query: 1011 GLRHA--PWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL 1068
G+ A P PR P G+ S+ P P + T P+++ +G
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 1069 SQP-PLPEK 1076
++P PL +K
Sbjct: 124 TRPGPLGQK 132
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 76.3 bits (186), Expect = 2e-13
Identities = 148/620 (23%), Positives = 206/620 (33%), Gaps = 119/620 (19%)
Query: 728 PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT--------------MC 773
P RP HP PL P+ P P S + P+A E H + T
Sbjct: 155 PARPYHPPPLFPPS------PQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA 208
Query: 774 PEGRYGHPGYPALVTYSYGGAV--PSYCPAYGRVPHSCGSPGEGRGYPSP---------- 821
P G P +P L GG + P P G S G P G+ +P P
Sbjct: 209 PPG--APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
Query: 822 ---------------GAHSPRAGS------ISPGSPPYPQSRKLSYEIPTEEGGDRYPLP 860
G + P A ++P PP P R L+ + G PLP
Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326
Query: 861 GHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQG 920
GHL S + P +GP TL SP P ++SS + P ++SS
Sbjct: 327 GHLPSPHAMGQGMGGLPPGPEKGP----TLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 921 KESTRRQDTRSPTSAP---TQRLS--PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVS 975
++ + S +++P +Q L P PP S + + + P+ S P S
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP 442
Query: 976 PTFPPSSPSDWPQERSPGGH--SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLT 1033
P PP PG S GA + P + H Q +
Sbjct: 443 PPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ--- 499
Query: 1034 PVPSQMPWLVASPEPPQSSPTP--------AFPLAASYDTNGLSQPPLPEKRHLPGPG-- 1083
Q + P PP + P P A P A S L +P P HLP P
Sbjct: 500 ---QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL-RPYPPGPAHLPPPHSQ 555
Query: 1084 ---QQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPE------PP------TQESQS 1128
Q GP GP +SS S P + Q P+ PP + + S
Sbjct: 556 VSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615
Query: 1129 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPP---- 1184
V +S YK + PGA+ ++ + + TPP
Sbjct: 616 TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG 675
Query: 1185 --PSAQPWKGDPVEQLVRHF-LIETGPKGV-KIKGCPSEPYFGSLSALVSQHSISPISLP 1240
P A P P V L GP G+ + P+ P G P+S
Sbjct: 676 TSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASG-----------PPLSAT 724
Query: 1241 CCLRIPSKDPLEETPEAPVP 1260
+ P+++ ETPE+PVP
Sbjct: 725 QIKQEPAEE--YETPESPVP 742
Score = 31.2 bits (69), Expect = 7.4
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 12/124 (9%)
Query: 423 SSSPEKIKGSTP-------RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTR 475
+SSP K ++P + PS T P + S +F G+ +
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT-SPPA 680
Query: 476 GPLDGSPYAQVQRPPRQTPPAPS--PEPPPPPMLSVSSDSGHSSTLTTEPAA--ESPGRP 531
GP P + P P PS P PPPP S ++ + EPA E+P P
Sbjct: 681 GPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESP 740
Query: 532 PPTA 535
P A
Sbjct: 741 VPPA 744
Score = 30.8 bits (68), Expect = 9.6
Identities = 15/48 (31%), Positives = 22/48 (45%)
Query: 490 PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAE 537
P PPA S P PP SS S S+ ++ ++ S P A++
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 76.3 bits (186), Expect = 2e-13
Identities = 148/620 (23%), Positives = 206/620 (33%), Gaps = 119/620 (19%)
Query: 728 PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT--------------MC 773
P RP HP PL P+ P P S + P+A E H + T
Sbjct: 155 PARPYHPPPLFPPS------PQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA 208
Query: 774 PEGRYGHPGYPALVTYSYGGAV--PSYCPAYGRVPHSCGSPGEGRGYPSP---------- 821
P G P +P L GG + P P G S G P G+ +P P
Sbjct: 209 PPG--APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
Query: 822 ---------------GAHSPRAGS------ISPGSPPYPQSRKLSYEIPTEEGGDRYPLP 860
G + P A ++P PP P R L+ + G PLP
Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326
Query: 861 GHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQG 920
GHL S + P +GP TL SP P ++SS + P ++SS
Sbjct: 327 GHLPSPHAMGQGMGGLPPGPEKGP----TLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 921 KESTRRQDTRSPTSAP---TQRLS--PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVS 975
++ + S +++P +Q L P PP S + + + P+ S P S
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP 442
Query: 976 PTFPPSSPSDWPQERSPGGH--SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLT 1033
P PP PG S GA + P + H Q +
Sbjct: 443 PPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ--- 499
Query: 1034 PVPSQMPWLVASPEPPQSSPTP--------AFPLAASYDTNGLSQPPLPEKRHLPGPG-- 1083
Q + P PP + P P A P A S L +P P HLP P
Sbjct: 500 ---QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL-RPYPPGPAHLPPPHSQ 555
Query: 1084 ---QQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPE------PP------TQESQS 1128
Q GP GP +SS S P + Q P+ PP + + S
Sbjct: 556 VSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615
Query: 1129 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPP---- 1184
V +S YK + PGA+ ++ + + TPP
Sbjct: 616 TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG 675
Query: 1185 --PSAQPWKGDPVEQLVRHF-LIETGPKGV-KIKGCPSEPYFGSLSALVSQHSISPISLP 1240
P A P P V L GP G+ + P+ P G P+S
Sbjct: 676 TSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASG-----------PPLSAT 724
Query: 1241 CCLRIPSKDPLEETPEAPVP 1260
+ P+++ ETPE+PVP
Sbjct: 725 QIKQEPAEE--YETPESPVP 742
Score = 31.2 bits (69), Expect = 7.4
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 12/124 (9%)
Query: 423 SSSPEKIKGSTP-------RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTR 475
+SSP K ++P + PS T P + S +F G+ +
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT-SPPA 680
Query: 476 GPLDGSPYAQVQRPPRQTPPAPS--PEPPPPPMLSVSSDSGHSSTLTTEPAA--ESPGRP 531
GP P + P P PS P PPPP S ++ + EPA E+P P
Sbjct: 681 GPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESP 740
Query: 532 PPTA 535
P A
Sbjct: 741 VPPA 744
Score = 30.8 bits (68), Expect = 9.6
Identities = 15/48 (31%), Positives = 22/48 (45%)
Query: 490 PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAE 537
P PPA S P PP SS S S+ ++ ++ S P A++
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 74.3 bits (181), Expect = 8e-13
Identities = 129/501 (25%), Positives = 169/501 (33%), Gaps = 55/501 (10%)
Query: 655 PPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAG 714
P G PA F A G PA P P PT L + G
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK-----GAPTTPAATLPSPK-GG 1070
Query: 715 EGWASEAGKPLLHPVRPGHPLPLLLPAC-GHHHAPMPDYSCLKPPKAG--EEGHEGCSYT 771
S G P P P P PA APMP + PK G H+G T
Sbjct: 1071 PATPSLKGAPTPPAATP--PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 772 MC-----PEGRY------GHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPS 820
P+G G P PA S G + + P + P G +
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLP------GHLASAGPLASAES 874
P SP+ +P + P S K P+ +G P G LA+ P + +
Sbjct: 1189 P---SPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243
Query: 875 LEPVSWREGPSGHSTLPRSPRDAP----CSASSELSGPSTPLHTSSPVQGKESTRRQDTR 930
P + P G P P+ AP + S G +TP H +P +
Sbjct: 1244 --PAATPPSPKGGPATP-PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 931 SPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQER 990
TS P +P A PP + G P P G+ P P A +P SP P+ P+ P
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPP--PKGA-PTPPAVTPPSPKGTPTLPATTPS-- 1355
Query: 991 SPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVA-SPEPP 1049
S GG + +S P P P + GP P SP P P P P A P P
Sbjct: 1356 SKGGPTTPSSKEGPTP---PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 1050 QSSP-TPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFA 1108
+ +P TP A+ + G PP L P G PA S
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-----GPATPSSKGDPTL 1467
Query: 1109 PLLSDNVPQTPEPPTQESQSN 1129
P ++ P+ P P Q + S+
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSS 1488
Score = 73.2 bits (178), Expect = 2e-12
Identities = 183/737 (24%), Positives = 246/737 (33%), Gaps = 111/737 (15%)
Query: 413 PFQASVEFVFSSSPEKIKGS-TPRNDP-SVSVDYNTTEPAVRWDSYENFNQHHEDSVDGS 470
P QA + SSSP+K + + P+ P S S T PA S +
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG------------ 952
Query: 471 LTHTRGPLDGSPYAQVQRPPRQTPPAP-----SPEP---PPPPMLSVSSDSGHSSTLTTE 522
GP SP PP TPP+P +P P P PP + S G +T + +
Sbjct: 953 -----GPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
Query: 523 PAAESPGRPPPTAAERQELDRLLGGCGVASGG-----RGAGRETAI------LDDEEQPT 571
A P PP+ G +G+ T + P+
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 572 VGGGPHLGVYPG-HRPGLSRHCSCRQGYREPCGVPNGGYYRPEGT--LERRRLAYGGYEG 628
GGP G P + S + G P P G P T + LA ++G
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPS--PKGAPMPPAATPPSPKGGLATPPHKG 1124
Query: 629 SPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALY 688
+P A + G PP G P T +P GL
Sbjct: 1125 APTTPAATPPSPK--------GGLATPPPKGAPTTPAATPPSP---------KGGLATPP 1167
Query: 689 PCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP-----LLHPVRPGHP-LPLLLPAC 742
P A A P + GL G A P L P G P P P
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227
Query: 743 --GHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGG--AVPSY 798
G P P P A +G T P+G P PA S G A P +
Sbjct: 1228 PKGGLATPSPK-GAPTTPAATPPSPKGGPATPPPKGA---PTPPAATPPSLKGGLATPPH 1283
Query: 799 ----CPAYGRVPHSCGSPGEG--RGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEI--PT 850
PA P G P +G P+P A +P + SPG+PP P+ + P+
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP-PKGAPTPPAVTPPS 1342
Query: 851 EEGGDRYPLPGHLASAGPLASAESLEPVSWREGPS---GHSTLPRSPRDAPCSASSELSG 907
+G P + GP + P PS G + P SP+ P S +
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK-GD 1401
Query: 908 PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPP-VSQAGTGKAPELPSGSGP 966
P++P P+ K++ TR + P S G+ PP V+ KAP + G
Sbjct: 1402 PTSP--AVIPLSPKKAPATPVTREGAATP----SKGDLTPPAVTPVSLKKAPATSAPKG- 1454
Query: 967 EPLAPS----PVSPTFPPSSPSDWPQERSPG-GHSDGASPRSPVPTTLPGLRHAPWQGPR 1021
P PS P P P SP + P + S +P +P P P L P
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL-------PA 1507
Query: 1022 GPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKR-HLP 1080
P SP P TP + P +A S TPA P P+K +P
Sbjct: 1508 VIPSSPKEVPATPSSRRDP--IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 1081 GPGQQPGPWGPEQASSP 1097
P + P ++ASSP
Sbjct: 1566 TPKEAPATPSSKEASSP 1582
Score = 68.2 bits (165), Expect = 5e-11
Identities = 84/326 (25%), Positives = 121/326 (37%), Gaps = 50/326 (15%)
Query: 805 VPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLA 864
+P S SP PG S + P S K E PTE+ G
Sbjct: 730 IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK---ECPTEDSG---------- 776
Query: 865 SAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPL-HTSSPVQGKES 923
++ +S +L ++ P G S P++ R S+ GP TP+ + SSPV E+
Sbjct: 777 ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA---GPDTPIGNLSSPVSPVEA 833
Query: 924 T----------RRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSP 973
+ +D+ + T +PT G P + K LP P PS
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP---TPSV 890
Query: 974 VSPTFPPSSPSDWPQERSPGGHSDGASPR----SPVPTTLPGL---RHAPWQGPRGPPDS 1026
V+ FP P+ +++P +SP+ +P P +P + AP P P S
Sbjct: 891 VNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPS 949
Query: 1027 PDGSPLTPVPSQMPWLVASPEP----------PQSSPTPAFPLAASYDTNGLSQPPLPEK 1076
P G P TP P P A+ P P+ +PTP P A G P P+
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP--PAATPPSPKGGPATPSPKG 1007
Query: 1077 RHLPGPGQQPGPWGPEQASSPARGIS 1102
P P P G A+ +G S
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGAS 1033
Score = 67.8 bits (164), Expect = 7e-11
Identities = 92/373 (24%), Positives = 132/373 (35%), Gaps = 49/373 (13%)
Query: 757 PPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTY------SYGGAVPSYCPAYGRVPHSCG 810
P K G G + P G P P ++ S+ G+ S PA P
Sbjct: 809 PTKKGSAGPD------TPIGNLSSPVSPVEASFLPENSLSFQGSKDS--PATTHSP---- 856
Query: 811 SPGEGRGYPSPGAH---SPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGH----- 862
+P +G P+P A SP+ ++ P P P L P + G P P
Sbjct: 857 TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL----PFPKEGPATPAPKQAPALS 912
Query: 863 LASAGPLASAESLEPV------SWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHT-S 915
+ S+ P + + P S + P+ + P SP+ P + S + + P+ P T
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA-PTPPAATPP 971
Query: 916 SPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVS 975
SP G + + +P +A G A P A T A PS G P P
Sbjct: 972 SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031
Query: 976 PTFPPSSPSDWPQERSPGGHSDGASPRSPVPT--------TLPGLRHAPWQGPRGPPDSP 1027
+ PP++ P+ +P +P T P L+ AP P P SP
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP-TPPAATPPSP 1090
Query: 1028 DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG 1087
G P TP P P + + PP A P T + PP P K L P +
Sbjct: 1091 KGGPATPSPKGAP-MPPAATPPSPKGGLATPPHKGAPTTPAATPPSP-KGGLATPPPKGA 1148
Query: 1088 PWGPEQASSPARG 1100
P P +G
Sbjct: 1149 PTTPAATPPSPKG 1161
Score = 67.4 bits (163), Expect = 9e-11
Identities = 162/658 (24%), Positives = 221/658 (33%), Gaps = 109/658 (16%)
Query: 480 GSPYAQ-----VQRPPRQTPPAPSPEP---------PPPPMLSVSSDSGHSSTLTTEPAA 525
GSP A PP TPP+P P P P ++ S G +T + + A
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
Query: 526 ESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGV--YPG 583
P PP+ GG S +GA A + + PH G P
Sbjct: 1081 TPPAATPPSPK---------GGPATPSP-KGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 584 HRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRR--LAYGGYEGSPQGYAEASMEKR 641
P S + G P P G P T + LA +G+P A +
Sbjct: 1131 ATPP-----SPKGGLATP--PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Query: 642 RLCRSLSEGLYPYPPEMGKPAT-GDFGYRAPGYREVVILEDP-----GLPALYPCPACEE 695
+ S P P P+ G +P P GL P A
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243
Query: 696 KLALPTAALYGLRLEREAGEGWASEAGKPLLH-----PVRPGHPLPLLL--PACGHHHAP 748
A P + G G A P L P G P P ++ P+ A
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 749 MPDYSCLKPPKAGEEGHEGCSYTMCPEGR-----------YGHPGYPALVTYSYGGAV-- 795
P PP A +G T P+G G P PA S GG
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 796 --------PSYCPAY-GRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSY 846
P+ P++ G + SP G PSP P + ++ P SP + ++
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG-DPTSPAVIPLSPKKAPATPVTR 1422
Query: 847 E-IPTEEGGDRYP---LPGHLASAGPLASAESLEPV--SWREGPSGHSTLPRSPRDAPC- 899
E T GD P P L A P SA P S + P+ + P SP++ P
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKA-PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 900 ----SASSELSGPSTPLHTSSP------------VQGKESTRRQDTRSPTSAPTQRLSPG 943
++SS P+TP +P V S+RR D +PT+ + +P
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR-DPIAPTATLLSKKTPA 1540
Query: 944 EALPPVSQAGTGKAPELPSGSGPEPLAPSPV-SPTFPPSSPSDWPQERSPGGHSDGASPR 1002
P +A A +PS P P+P +P P S + P +P + SP+
Sbjct: 1541 TLAP--KEALIPPAMTVPSPK-KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 1003 S---PVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQS---SPT 1054
P T P + AP P P SP+ P TP P P + P P S SPT
Sbjct: 1598 ELLIPPAVTSPSPKEAPTP-PAVTPPSPEKGPATPAPKGTP--TSPPVTPSSLKDSPT 1652
Score = 48.9 bits (115), Expect = 3e-05
Identities = 136/569 (23%), Positives = 182/569 (31%), Gaps = 117/569 (20%)
Query: 481 SPYAQVQRPPRQTPPAPSPEP--------PPPPMLSVSSDSGHSSTLTTEPAAES----- 527
SP PP TPP+P P P PP ++ S G + T P+++
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 528 ---PGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGH 584
G PP A + G A R AI + PT P
Sbjct: 1364 SSKEGPTPPAATPSHK-------GGPAMTPPSPKRGPAIPSPKGDPTS---------PAV 1407
Query: 585 RPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLE---RRRLAYGGYEGSPQGYAEASMEKR 641
P + RE P+ G P ++ A +G P A S +
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP---ATPSSKGD 1464
Query: 642 RLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPC--------PAC 693
+++ PP + AT +AP + P LPA+ P P+
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPA--TPAPMGAPTLPAVIPSSPKEVPATPSS 1522
Query: 694 EEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYS 753
PTA L + A+ A K L P P P PA P P
Sbjct: 1523 RRDPIAPTATLLSKKTP-------ATLAPKEALIPPAMTVPSPKKTPAI-----PTP--- 1567
Query: 754 CLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPG 813
K A E S Y G P+ AV S P P + P
Sbjct: 1568 --KEAPATPSSKEASSPPAVTPSTY--KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623
Query: 814 EGRGYPSPGAH-SPRAGSISPGS----PPYPQSR--KLSYEIPTEEGGDRYPLPGHLASA 866
+G +P +P + ++P S P P S K+ +P G LP A
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG----LP---AKK 1676
Query: 867 GPLASAESL-------EPVSWREGPSGHSTLPRSPRDAP-CSASSELSGPSTPLHTSSPV 918
GP A E L P+ G T S P C S +G PL T +P
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736
Query: 919 Q----GKESTRRQDTRSPTSAPTQRLSPGEA--------------LPPVSQAGTGKAPEL 960
K+S++ + + +P L+P E+ LP A AP
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796
Query: 961 PSGSGPEPLAPSPVSPT------FPPSSP 983
P PLAPSPV PT F PSSP
Sbjct: 1797 PVSL---PLAPSPV-PTLPPKQQFLPSSP 1821
Score = 47.8 bits (112), Expect = 8e-05
Identities = 99/412 (24%), Positives = 160/412 (38%), Gaps = 66/412 (16%)
Query: 833 PGSPPYPQSRKLS-------YEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPS 885
P SPP P L + PT++ D +P L A P + A++ ++ ++ P+
Sbjct: 504 PVSPPLPDPEDLKNLPSSVLVKFPTQK--DLQTVPASLEGA-PFSPAQA--GLTTKKDPT 558
Query: 886 GHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL---SP 942
+ +P+++P S S S P PL + + K P S+ T L S
Sbjct: 559 VLPLVQAAPKNSP-SFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSS 617
Query: 943 GEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPT---FPPSS--PSDWPQERSPGG--H 995
+ S AG P +GP L S ++PT FP S P+ + G +
Sbjct: 618 ASVIKTDSYAG-------PDSAGPL-LKSSLITPTVAAFPLESADPAGVAPTTAKGTSTY 669
Query: 996 SDGASPRSPVPTTLPGLRHAPWQGPRGP----PDSPDGSPLTPVPSQ----MPWLVASPE 1047
+ ASP +L H +G P + + P+ P P + LV +PE
Sbjct: 670 TTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE 729
Query: 1048 PPQSSPTPAFPLA----ASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISH 1103
P+S P+P+ P A + +G+S P + P A++ ++G
Sbjct: 730 IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP-VASSPKECPTEDSGASATASSKGTLT 788
Query: 1104 HV--TFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGA 1161
++ + +PL PQT PPT++ + DT +S +A +
Sbjct: 789 YLADSPSPLGVSVSPQTKRPPTKKGSAG----PDTPIGNLSSPVSPVEA----------S 834
Query: 1162 FLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI 1213
FL +S SFQG+ +P P + KG P V PKGV +
Sbjct: 835 FLPENSLSFQGSKDSPATTHSPTPPSP--KGAPTPSAV----TPLSPKGVTL 880
Score = 41.6 bits (96), Expect = 0.005
Identities = 99/412 (24%), Positives = 148/412 (35%), Gaps = 52/412 (12%)
Query: 858 PLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELS---GPSTPLHT 914
P P + P++SA S+ + GP+ +P+ P SA+++ S PST T
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
Query: 915 SSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL--------PSGSGP 966
V +S+ T+ P PP+S A A + PS S P
Sbjct: 77 PLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAP 136
Query: 967 ---EPLAPSPV--SPTFPPSSPSDWPQ--ERSPGGHSDGASPRSP--VPTTLPGLRHAPW 1017
LAP V S FPP+ + P G ++P +P T L +
Sbjct: 137 LALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVV 196
Query: 1018 QGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPE-- 1075
P+G P P + S +P+ +P S + P T ++ P + +
Sbjct: 197 PNPKGTPSPP------CIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTT 250
Query: 1076 -KRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV----PQTPEPPTQESQSNV 1130
L P Q PG + SP +S P+++ + P TP P S +
Sbjct: 251 ISSVLISP-QNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTP-PDFPISLGSH 308
Query: 1131 KFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPW 1190
S F L + AL DP I HS GA + + PP P
Sbjct: 309 LAPLHQSSFGSVQLLGQTGPSAL---SDPTVKTISVDHSSTGASYPSQRSVIPP---LPS 362
Query: 1191 KGDPVEQLVRHF-----LIETGPKGVKIKGC-PSEPYFGSLSALVSQHSISP 1236
+ + V V F ++ GP + C PS GSL+ S S+SP
Sbjct: 363 RNEVVPATVAAFPVVAPSVDKGPSTISSITCSPS----GSLNVATS-FSLSP 409
Score = 35.0 bits (79), Expect = 0.51
Identities = 86/394 (21%), Positives = 136/394 (34%), Gaps = 53/394 (13%)
Query: 884 PSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG 943
PS + +P + P A S GPST + G + + SPT++ + SP
Sbjct: 361 PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420
Query: 944 E-------ALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 996
A PVS GT + P +A +P + TF ++ P P +
Sbjct: 421 ATYHYPLVAQMPVSSVGTTPLVV----TNPCTIAAAPTT-TFEVATCVSPPMSSGPISNI 475
Query: 997 DGASP----RSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1052
+ SP +PV P + A P PD L +PS + LV P
Sbjct: 476 EPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSV--LVKFPTQKDLQ 533
Query: 1053 PTPAFPLAASYD--TNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFA-P 1109
PA A + GL+ P L + P +SSP +S T A
Sbjct: 534 TVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK 593
Query: 1110 LLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHS 1169
L + +P + S V + + +++K DS++
Sbjct: 594 SLGEPLPIGKPASSMTSPLGV-----------------NSSASVIK---------TDSYA 627
Query: 1170 FQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYF-GSLSAL 1228
+ G LK + P+ + P+E + T KG + P+ G++S
Sbjct: 628 GPDSAGPLLKSSLITPTVAAF---PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA 684
Query: 1229 VSQHSISPISLPCCLRIPSKDPLEETPEAPVPTN 1262
H + +L +P+ E P AP P N
Sbjct: 685 PKNHPVKEGTLTTLPLVPTAS--ENCPVAPSPQN 716
Score = 30.8 bits (68), Expect = 9.6
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 9/80 (11%)
Query: 478 LDGSPYAQVQRPPRQTPPAPSPE-----PPPPPMLSVSSDSGHSSTLTTEPAAESPGRPP 532
L SP ++ P + PA E PP P +S S L P +S G P
Sbjct: 1817 LPSSPGLVLESPSKPLAPADEDELLPLIPPEP----ISGGVPFQSVLVNMPTPKSAGIPV 1872
Query: 533 PTAAERQELDRLLGGCGVAS 552
PT + +Q + + G G S
Sbjct: 1873 PTPSAKQPVTKNNKGSGTES 1892
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 73.6 bits (179), Expect = 1e-12
Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)
Query: 820 SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 877
+P +P +P +P P P + K + P E P P P E
Sbjct: 228 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 281
Query: 878 VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 937
+ P+ + P +P++ P + + P+TP + P KE T PT+
Sbjct: 282 TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 329
Query: 938 QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 997
P A T K P + P P AP +PT P P+E +P +
Sbjct: 330 ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Query: 998 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1054
+ +P+ P PTT + AP P + +P TP PS +P P+ P
Sbjct: 380 PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 435
Query: 1055 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1107
P P + T P P+ K+ P ++P P P++ ++P T
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 494
Query: 1108 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1167
L+ P+ P P T E + + T +P + +A A K+P
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 548
Query: 1168 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1223
K P +P P E T PKG + P+ P
Sbjct: 549 --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 594
Query: 1224 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1281
+ L + P S C P+ K TP+ P PT A +G A + L
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654
Query: 1282 TSVETESLTGPQAVA----RASSAALSCSPRPT 1310
+ T P+ +A + ++ S P PT
Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 878
P +P+ + + P P + K + P E + P P P E
Sbjct: 270 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Query: 879 SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 931
P+ P +P++ P + + P+TP + + S +
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389
Query: 932 PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 989
PT+ + + E P +++ T K P + P P P +PT P P+E
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449
Query: 990 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1035
+P + A +P+ P PTT AP + P +P+ +P P
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 507
Query: 1036 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1090
P+ L +PE P + P P P AA+ +T P P K P ++P P
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 566
Query: 1091 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1149
P E A + +G T L + P TP+ P + + + TS KP + +
Sbjct: 567 PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621
Query: 1150 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1209
A K+P ++ G A P P K P E L T K
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 674
Query: 1210 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1261
G K P+ P +A + +P + K P TPE P PT
Sbjct: 675 GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 719
Score = 64.7 bits (156), Expect = 6e-10
Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)
Query: 819 PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 873
PSP A + + +P P P + K + P E P P P E
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 433
Query: 874 SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 932
+ P+ P +P++ P +++ P+TP + P KE+ +
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 491
Query: 933 TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 992
+ P ++L+P P AP P P P P +PT P ++ + P+E +P
Sbjct: 492 PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 548
Query: 993 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1052
+P+ P PTT AP P +P G+ T + P P P + +
Sbjct: 549 ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600
Query: 1053 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1110
PT P + + D P K P ++P P P E A + +G T
Sbjct: 601 PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 651
Query: 1111 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1159
L + P TP+ P + + TS KP + + A K+P
Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 700
Score = 53.5 bits (127), Expect = 1e-06
Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)
Query: 841 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 900
S K + I D P LA P A + P + P +P++ P S
Sbjct: 172 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 226
Query: 901 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 956
+ + P+T S+P KE +PT+ APT P P T K
Sbjct: 227 TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 284
Query: 957 --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1009
AP + P P+P +P P P++P + P+E +P +P+ P PTT
Sbjct: 285 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 338
Query: 1010 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1069
P P + +P P P+ EP ++P P +
Sbjct: 339 E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 385
Query: 1070 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1128
+ P P + P ++P P + A + + S T P + P+ P P T + +
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 443
Query: 1129 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1187
+ +P + + A K+P +++ A K+ T P
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 498
Query: 1188 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1247
P + L T P+ P EP A + + +P +
Sbjct: 499 APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 551
Query: 1248 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1304
K+P TP+ P PT A +G A + L + T P+ +A ++ + +
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 1305 C-SPRPT 1310
C P PT
Sbjct: 612 CDKPAPT 618
Score = 48.9 bits (115), Expect = 3e-05
Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 880
P +P+A + P +P P PT P A P +A P +
Sbjct: 530 PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 583
Query: 881 REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 940
+E T P+ P A EL+ +T TS+ T + T T
Sbjct: 584 KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 634
Query: 941 SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 997
+P E P + + P+ + P+ AP ++PT P S+ SD P +P +
Sbjct: 635 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 693
Query: 998 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1056
+P+ P PTT P+ P P +P+ P T P P SP +
Sbjct: 694 PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 742
Query: 1057 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1103
P ++ T N +P +P + P PE ++ R
Sbjct: 743 TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 795
Query: 1104 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1139
T AP ++ T E T+ +Q QDT+ F
Sbjct: 796 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 837
Score = 36.2 bits (82), Expect = 0.23
Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)
Query: 390 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 443
T GP LT PK+ + A T + P +++ ++P++ +T ++ P+ +
Sbjct: 204 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 262
Query: 444 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 501
T EPA E + + + P + +P ++P TP P+P
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 321
Query: 502 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 538
P P + + + T EPA +P P PTA ++
Sbjct: 322 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 355
Score = 33.9 bits (76), Expect = 1.1
Identities = 47/236 (19%), Positives = 74/236 (31%), Gaps = 27/236 (11%)
Query: 888 STLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP 947
ST P+ P + L S +S KE+T +T+ T+ Q + G+
Sbjct: 113 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT--VETKETTTTNKQTSTDGKEK- 169
Query: 948 PVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPT 1007
T A E S +P S +P + P +P+ P PT
Sbjct: 170 ------TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPT 219
Query: 1008 TLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNG 1067
T P + +P P P+ + +P+ P + T + P
Sbjct: 220 T--------------PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 265
Query: 1068 LSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPT 1123
++ P P P P P S+P T + P+ P P T
Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 321
Score = 32.7 bits (73), Expect = 2.5
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP + P++T P EP P T +PA +P P
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 716
Query: 532 PPTAAE 537
PPT +E
Sbjct: 717 PPTTSE 722
Score = 32.3 bits (72), Expect = 3.3
Identities = 17/66 (25%), Positives = 27/66 (40%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP +P P++ EP P + S + + TT+ A +P P
Sbjct: 203 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 262
Query: 532 PPTAAE 537
PT +
Sbjct: 263 APTTTK 268
Score = 31.6 bits (70), Expect = 5.6
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 528
T T+ P SP + P T AP+ P P + S+ + S T T EPA +P
Sbjct: 375 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431
Query: 529 GRPPPTAAER 538
P PT ++
Sbjct: 432 KEPAPTTPKK 441
Score = 31.6 bits (70), Expect = 5.6
Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 470 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 529
S T T+ P +P + P TP P+P P P + + + T T +PA +P
Sbjct: 419 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 472
Query: 530 RPPPT 534
P PT
Sbjct: 473 EPAPT 477
Score = 30.8 bits (68), Expect = 9.6
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 489 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 534
P PAP+ P+ P P L+ ++ G +ST + +PA +P PT
Sbjct: 649 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 73.6 bits (179), Expect = 1e-12
Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)
Query: 820 SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 877
+P +P +P +P P P + K + P E P P P E
Sbjct: 269 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 322
Query: 878 VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 937
+ P+ + P +P++ P + + P+TP + P KE T PT+
Sbjct: 323 TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 370
Query: 938 QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 997
P A T K P + P P AP +PT P P+E +P +
Sbjct: 371 ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Query: 998 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1054
+ +P+ P PTT + AP P + +P TP PS +P P+ P
Sbjct: 421 PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 476
Query: 1055 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1107
P P + T P P+ K+ P ++P P P++ ++P T
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 535
Query: 1108 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1167
L+ P+ P P T E + + T +P + +A A K+P
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 589
Query: 1168 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1223
K P +P P E T PKG + P+ P
Sbjct: 590 --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 635
Query: 1224 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1281
+ L + P S C P+ K TP+ P PT A +G A + L
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695
Query: 1282 TSVETESLTGPQAVA----RASSAALSCSPRPT 1310
+ T P+ +A + ++ S P PT
Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 878
P +P+ + + P P + K + P E + P P P E
Sbjct: 311 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Query: 879 SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 931
P+ P +P++ P + + P+TP + + S +
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430
Query: 932 PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 989
PT+ + + E P +++ T K P + P P P +PT P P+E
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490
Query: 990 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1035
+P + A +P+ P PTT AP + P +P+ +P P
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 548
Query: 1036 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1090
P+ L +PE P + P P P AA+ +T P P K P ++P P
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 607
Query: 1091 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1149
P E A + +G T L + P TP+ P + + + TS KP + +
Sbjct: 608 PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662
Query: 1150 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1209
A K+P ++ G A P P K P E L T K
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 715
Query: 1210 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1261
G K P+ P +A + +P + K P TPE P PT
Sbjct: 716 GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 760
Score = 64.7 bits (156), Expect = 6e-10
Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)
Query: 819 PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 873
PSP A + + +P P P + K + P E P P P E
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 474
Query: 874 SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 932
+ P+ P +P++ P +++ P+TP + P KE+ +
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 532
Query: 933 TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 992
+ P ++L+P P AP P P P P +PT P ++ + P+E +P
Sbjct: 533 PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 589
Query: 993 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1052
+P+ P PTT AP P +P G+ T + P P P + +
Sbjct: 590 ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641
Query: 1053 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1110
PT P + + D P K P ++P P P E A + +G T
Sbjct: 642 PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 692
Query: 1111 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1159
L + P TP+ P + + TS KP + + A K+P
Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 741
Score = 53.5 bits (127), Expect = 1e-06
Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)
Query: 841 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 900
S K + I D P LA P A + P + P +P++ P S
Sbjct: 213 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 267
Query: 901 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 956
+ + P+T S+P KE +PT+ APT P P T K
Sbjct: 268 TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 325
Query: 957 --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1009
AP + P P+P +P P P++P + P+E +P +P+ P PTT
Sbjct: 326 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 379
Query: 1010 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1069
P P + +P P P+ EP ++P P +
Sbjct: 380 E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 426
Query: 1070 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1128
+ P P + P ++P P + A + + S T P + P+ P P T + +
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 484
Query: 1129 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1187
+ +P + + A K+P +++ A K+ T P
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 539
Query: 1188 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1247
P + L T P+ P EP A + + +P +
Sbjct: 540 APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 592
Query: 1248 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1304
K+P TP+ P PT A +G A + L + T P+ +A ++ + +
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 1305 C-SPRPT 1310
C P PT
Sbjct: 653 CDKPAPT 659
Score = 48.9 bits (115), Expect = 3e-05
Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 880
P +P+A + P +P P PT P A P +A P +
Sbjct: 571 PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 624
Query: 881 REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 940
+E T P+ P A EL+ +T TS+ T + T T
Sbjct: 625 KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675
Query: 941 SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 997
+P E P + + P+ + P+ AP ++PT P S+ SD P +P +
Sbjct: 676 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 734
Query: 998 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1056
+P+ P PTT P+ P P +P+ P T P P SP +
Sbjct: 735 PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783
Query: 1057 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1103
P ++ T N +P +P + P PE ++ R
Sbjct: 784 TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 836
Query: 1104 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1139
T AP ++ T E T+ +Q QDT+ F
Sbjct: 837 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 878
Score = 36.2 bits (82), Expect = 0.23
Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)
Query: 390 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 443
T GP LT PK+ + A T + P +++ ++P++ +T ++ P+ +
Sbjct: 245 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 303
Query: 444 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 501
T EPA E + + + P + +P ++P TP P+P
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 362
Query: 502 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 538
P P + + + T EPA +P P PTA ++
Sbjct: 363 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 396
Score = 33.9 bits (76), Expect = 1.1
Identities = 47/236 (19%), Positives = 74/236 (31%), Gaps = 27/236 (11%)
Query: 888 STLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP 947
ST P+ P + L S +S KE+T +T+ T+ Q + G+
Sbjct: 154 STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT--VETKETTTTNKQTSTDGKEK- 210
Query: 948 PVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPT 1007
T A E S +P S +P + P +P+ P PT
Sbjct: 211 ------TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPT 260
Query: 1008 TLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNG 1067
T P + +P P P+ + +P+ P + T + P
Sbjct: 261 T--------------PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 306
Query: 1068 LSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPT 1123
++ P P P P P S+P T + P+ P P T
Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 362
Score = 32.7 bits (73), Expect = 2.5
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP + P++T P EP P T +PA +P P
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 757
Query: 532 PPTAAE 537
PPT +E
Sbjct: 758 PPTTSE 763
Score = 32.3 bits (72), Expect = 3.3
Identities = 17/66 (25%), Positives = 27/66 (40%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP +P P++ EP P + S + + TT+ A +P P
Sbjct: 244 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 303
Query: 532 PPTAAE 537
PT +
Sbjct: 304 APTTTK 309
Score = 31.6 bits (70), Expect = 5.6
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 528
T T+ P SP + P T AP+ P P + S+ + S T T EPA +P
Sbjct: 416 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472
Query: 529 GRPPPTAAER 538
P PT ++
Sbjct: 473 KEPAPTTPKK 482
Score = 31.6 bits (70), Expect = 5.6
Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 470 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 529
S T T+ P +P + P TP P+P P P + + + T T +PA +P
Sbjct: 460 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 513
Query: 530 RPPPT 534
P PT
Sbjct: 514 EPAPT 518
Score = 30.8 bits (68), Expect = 9.6
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 489 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 534
P PAP+ P+ P P L+ ++ G +ST + +PA +P PT
Sbjct: 690 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 73.6 bits (179), Expect = 1e-12
Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)
Query: 820 SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 877
+P +P +P +P P P + K + P E P P P E
Sbjct: 321 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 374
Query: 878 VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 937
+ P+ + P +P++ P + + P+TP + P KE T PT+
Sbjct: 375 TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 422
Query: 938 QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 997
P A T K P + P P AP +PT P P+E +P +
Sbjct: 423 ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 472
Query: 998 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1054
+ +P+ P PTT + AP P + +P TP PS +P P+ P
Sbjct: 473 PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 528
Query: 1055 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1107
P P + T P P+ K+ P ++P P P++ ++P T
Sbjct: 529 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 587
Query: 1108 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1167
L+ P+ P P T E + + T +P + +A A K+P
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 641
Query: 1168 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1223
K P +P P E T PKG + P+ P
Sbjct: 642 --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 687
Query: 1224 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1281
+ L + P S C P+ K TP+ P PT A +G A + L
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747
Query: 1282 TSVETESLTGPQAVA----RASSAALSCSPRPT 1310
+ T P+ +A + ++ S P PT
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 878
P +P+ + + P P + K + P E + P P P E
Sbjct: 363 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Query: 879 SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 931
P+ P +P++ P + + P+TP + + S +
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482
Query: 932 PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 989
PT+ + + E P +++ T K P + P P P +PT P P+E
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542
Query: 990 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1035
+P + A +P+ P PTT AP + P +P+ +P P
Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 600
Query: 1036 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1090
P+ L +PE P + P P P AA+ +T P P K P ++P P
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 659
Query: 1091 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1149
P E A + +G T L + P TP+ P + + + TS KP + +
Sbjct: 660 PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 1150 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1209
A K+P ++ G A P P K P E L T K
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 767
Query: 1210 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1261
G K P+ P +A + +P + K P TPE P PT
Sbjct: 768 GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 812
Score = 64.7 bits (156), Expect = 6e-10
Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)
Query: 819 PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 873
PSP A + + +P P P + K + P E P P P E
Sbjct: 473 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 526
Query: 874 SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 932
+ P+ P +P++ P +++ P+TP + P KE+ +
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 584
Query: 933 TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 992
+ P ++L+P P AP P P P P +PT P ++ + P+E +P
Sbjct: 585 PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 641
Query: 993 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1052
+P+ P PTT AP P +P G+ T + P P P + +
Sbjct: 642 ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693
Query: 1053 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1110
PT P + + D P K P ++P P P E A + +G T
Sbjct: 694 PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 744
Query: 1111 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1159
L + P TP+ P + + TS KP + + A K+P
Sbjct: 745 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793
Score = 53.5 bits (127), Expect = 1e-06
Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)
Query: 841 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 900
S K + I D P LA P A + P + P +P++ P S
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 319
Query: 901 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 956
+ + P+T S+P KE +PT+ APT P P T K
Sbjct: 320 TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 377
Query: 957 --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1009
AP + P P+P +P P P++P + P+E +P +P+ P PTT
Sbjct: 378 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 431
Query: 1010 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1069
P P + +P P P+ EP ++P P +
Sbjct: 432 E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 478
Query: 1070 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1128
+ P P + P ++P P + A + + S T P + P+ P P T + +
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 536
Query: 1129 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1187
+ +P + + A K+P +++ A K+ T P
Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 591
Query: 1188 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1247
P + L T P+ P EP A + + +P +
Sbjct: 592 APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 644
Query: 1248 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1304
K+P TP+ P PT A +G A + L + T P+ +A ++ + +
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704
Query: 1305 C-SPRPT 1310
C P PT
Sbjct: 705 CDKPAPT 711
Score = 48.9 bits (115), Expect = 3e-05
Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 880
P +P+A + P +P P PT P A P +A P +
Sbjct: 623 PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 676
Query: 881 REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 940
+E T P+ P A EL+ +T TS+ T + T T
Sbjct: 677 KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 727
Query: 941 SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 997
+P E P + + P+ + P+ AP ++PT P S+ SD P +P +
Sbjct: 728 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 786
Query: 998 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1056
+P+ P PTT P+ P P +P+ P T P P SP +
Sbjct: 787 PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 835
Query: 1057 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1103
P ++ T N +P +P + P PE ++ R
Sbjct: 836 TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 888
Query: 1104 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1139
T AP ++ T E T+ +Q QDT+ F
Sbjct: 889 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 930
Score = 37.0 bits (84), Expect = 0.13
Identities = 67/368 (18%), Positives = 116/368 (31%), Gaps = 52/368 (14%)
Query: 799 CPAYGRV---PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD 855
CP Y H+ SP + P P S S + SP P +K I +EE +
Sbjct: 56 CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE 115
Query: 856 RYPLPGHLASAGPLASAES---LEPVSWREGPSGHSTLPRS--PRDAPCSASSELSGPST 910
+ + + S+ +S+ S + + + + + L + +D + + + P
Sbjct: 116 EHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 175
Query: 911 PL------------------HTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQA 952
P+ TS+ K ST SP + ++P +LPP S
Sbjct: 176 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST------SPKITTAKPINPRPSLPPNSDT 229
Query: 953 G-----------------TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGH 995
T + S G E + + + +S D
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 996 SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP 1055
+P++ T P L P P + +P P P+ + +P+ P + T
Sbjct: 290 P---TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346
Query: 1056 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1115
+ P ++ P P P P P S+P T +
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406
Query: 1116 PQTPEPPT 1123
P+ P P T
Sbjct: 407 PKEPAPTT 414
Score = 36.2 bits (82), Expect = 0.23
Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)
Query: 390 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 443
T GP LT PK+ + A T + P +++ ++P++ +T ++ P+ +
Sbjct: 297 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 355
Query: 444 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 501
T EPA E + + + P + +P ++P TP P+P
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 414
Query: 502 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 538
P P + + + T EPA +P P PTA ++
Sbjct: 415 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 448
Score = 32.7 bits (73), Expect = 2.5
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP + P++T P EP P T +PA +P P
Sbjct: 764 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 809
Query: 532 PPTAAE 537
PPT +E
Sbjct: 810 PPTTSE 815
Score = 32.3 bits (72), Expect = 3.3
Identities = 17/66 (25%), Positives = 27/66 (40%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP +P P++ EP P + S + + TT+ A +P P
Sbjct: 296 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 355
Query: 532 PPTAAE 537
PT +
Sbjct: 356 APTTTK 361
Score = 31.6 bits (70), Expect = 5.6
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 528
T T+ P SP + P T AP+ P P + S+ + S T T EPA +P
Sbjct: 468 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524
Query: 529 GRPPPTAAER 538
P PT ++
Sbjct: 525 KEPAPTTPKK 534
Score = 31.6 bits (70), Expect = 5.6
Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 470 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 529
S T T+ P +P + P TP P+P P P + + + T T +PA +P
Sbjct: 512 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 565
Query: 530 RPPPT 534
P PT
Sbjct: 566 EPAPT 570
Score = 30.8 bits (68), Expect = 9.6
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 489 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 534
P PAP+ P+ P P L+ ++ G +ST + +PA +P PT
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 73.6 bits (179), Expect = 1e-12
Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)
Query: 820 SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 877
+P +P +P +P P P + K + P E P P P E
Sbjct: 362 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 415
Query: 878 VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 937
+ P+ + P +P++ P + + P+TP + P KE T PT+
Sbjct: 416 TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 463
Query: 938 QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 997
P A T K P + P P AP +PT P P+E +P +
Sbjct: 464 ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 513
Query: 998 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1054
+ +P+ P PTT + AP P + +P TP PS +P P+ P
Sbjct: 514 PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 569
Query: 1055 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1107
P P + T P P+ K+ P ++P P P++ ++P T
Sbjct: 570 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 628
Query: 1108 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1167
L+ P+ P P T E + + T +P + +A A K+P
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 682
Query: 1168 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1223
K P +P P E T PKG + P+ P
Sbjct: 683 --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 728
Query: 1224 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1281
+ L + P S C P+ K TP+ P PT A +G A + L
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788
Query: 1282 TSVETESLTGPQAVA----RASSAALSCSPRPT 1310
+ T P+ +A + ++ S P PT
Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 878
P +P+ + + P P + K + P E + P P P E
Sbjct: 404 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Query: 879 SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 931
P+ P +P++ P + + P+TP + + S +
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523
Query: 932 PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 989
PT+ + + E P +++ T K P + P P P +PT P P+E
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583
Query: 990 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1035
+P + A +P+ P PTT AP + P +P+ +P P
Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 641
Query: 1036 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1090
P+ L +PE P + P P P AA+ +T P P K P ++P P
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 700
Query: 1091 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1149
P E A + +G T L + P TP+ P + + + TS KP + +
Sbjct: 701 PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 1150 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1209
A K+P ++ G A P P K P E L T K
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 808
Query: 1210 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1261
G K P+ P +A + +P + K P TPE P PT
Sbjct: 809 GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 853
Score = 64.7 bits (156), Expect = 6e-10
Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)
Query: 819 PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 873
PSP A + + +P P P + K + P E P P P E
Sbjct: 514 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 567
Query: 874 SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 932
+ P+ P +P++ P +++ P+TP + P KE+ +
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 625
Query: 933 TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 992
+ P ++L+P P AP P P P P +PT P ++ + P+E +P
Sbjct: 626 PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 682
Query: 993 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1052
+P+ P PTT AP P +P G+ T + P P P + +
Sbjct: 683 ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734
Query: 1053 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1110
PT P + + D P K P ++P P P E A + +G T
Sbjct: 735 PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 785
Query: 1111 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1159
L + P TP+ P + + TS KP + + A K+P
Sbjct: 786 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834
Score = 53.5 bits (127), Expect = 1e-06
Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)
Query: 841 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 900
S K + I D P LA P A + P + P +P++ P S
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 360
Query: 901 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 956
+ + P+T S+P KE +PT+ APT P P T K
Sbjct: 361 TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 418
Query: 957 --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1009
AP + P P+P +P P P++P + P+E +P +P+ P PTT
Sbjct: 419 EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 472
Query: 1010 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1069
P P + +P P P+ EP ++P P +
Sbjct: 473 E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 519
Query: 1070 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1128
+ P P + P ++P P + A + + S T P + P+ P P T + +
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 577
Query: 1129 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1187
+ +P + + A K+P +++ A K+ T P
Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 632
Query: 1188 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1247
P + L T P+ P EP A + + +P +
Sbjct: 633 APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 685
Query: 1248 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1304
K+P TP+ P PT A +G A + L + T P+ +A ++ + +
Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745
Query: 1305 C-SPRPT 1310
C P PT
Sbjct: 746 CDKPAPT 752
Score = 48.9 bits (115), Expect = 3e-05
Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)
Query: 821 PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 880
P +P+A + P +P P PT P A P +A P +
Sbjct: 664 PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 717
Query: 881 REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 940
+E T P+ P A EL+ +T TS+ T + T T
Sbjct: 718 KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 768
Query: 941 SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 997
+P E P + + P+ + P+ AP ++PT P S+ SD P +P +
Sbjct: 769 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 827
Query: 998 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1056
+P+ P PTT P+ P P +P+ P T P P SP +
Sbjct: 828 PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 876
Query: 1057 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1103
P ++ T N +P +P + P PE ++ R
Sbjct: 877 TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 929
Query: 1104 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1139
T AP ++ T E T+ +Q QDT+ F
Sbjct: 930 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 971
Score = 37.0 bits (84), Expect = 0.13
Identities = 67/368 (18%), Positives = 116/368 (31%), Gaps = 52/368 (14%)
Query: 799 CPAYGRV---PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD 855
CP Y H+ SP + P P S S + SP P +K I +EE +
Sbjct: 97 CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE 156
Query: 856 RYPLPGHLASAGPLASAES---LEPVSWREGPSGHSTLPRS--PRDAPCSASSELSGPST 910
+ + + S+ +S+ S + + + + + L + +D + + + P
Sbjct: 157 EHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 216
Query: 911 PL------------------HTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQA 952
P+ TS+ K ST SP + ++P +LPP S
Sbjct: 217 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST------SPKITTAKPINPRPSLPPNSDT 270
Query: 953 G-----------------TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGH 995
T + S G E + + + +S D
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 996 SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP 1055
+P++ T P L P P + +P P P+ + +P+ P + T
Sbjct: 331 P---TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387
Query: 1056 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1115
+ P ++ P P P P P S+P T +
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447
Query: 1116 PQTPEPPT 1123
P+ P P T
Sbjct: 448 PKEPAPTT 455
Score = 36.2 bits (82), Expect = 0.23
Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)
Query: 390 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 443
T GP LT PK+ + A T + P +++ ++P++ +T ++ P+ +
Sbjct: 338 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 396
Query: 444 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 501
T EPA E + + + P + +P ++P TP P+P
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 455
Query: 502 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 538
P P + + + T EPA +P P PTA ++
Sbjct: 456 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 489
Score = 32.7 bits (73), Expect = 2.5
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP + P++T P EP P T +PA +P P
Sbjct: 805 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 850
Query: 532 PPTAAE 537
PPT +E
Sbjct: 851 PPTTSE 856
Score = 32.3 bits (72), Expect = 3.3
Identities = 17/66 (25%), Positives = 27/66 (40%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 531
T T+GP +P P++ EP P + S + + TT+ A +P P
Sbjct: 337 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 396
Query: 532 PPTAAE 537
PT +
Sbjct: 397 APTTTK 402
Score = 31.6 bits (70), Expect = 5.6
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Query: 472 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 528
T T+ P SP + P T AP+ P P + S+ + S T T EPA +P
Sbjct: 509 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565
Query: 529 GRPPPTAAER 538
P PT ++
Sbjct: 566 KEPAPTTPKK 575
Score = 31.6 bits (70), Expect = 5.6
Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 470 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 529
S T T+ P +P + P TP P+P P P + + + T T +PA +P
Sbjct: 553 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 606
Query: 530 RPPPT 534
P PT
Sbjct: 607 EPAPT 611
Score = 30.8 bits (68), Expect = 9.6
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 489 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 534
P PAP+ P+ P P L+ ++ G +ST + +PA +P PT
Sbjct: 783 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 73.6 bits (179), Expect = 1e-12
Identities = 97/349 (27%), Positives = 118/349 (33%), Gaps = 45/349 (12%)
Query: 784 PALVTYSYGGAVPSYCPAYGRVPHSCGSP-GEGRGYPSPGAHSPRAGSISPGSP--PYPQ 840
P+L+ + GA P G P SP G+ +G P G + P+ PG P P PQ
Sbjct: 29 PSLIAGNPQGAPPQG----GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 84
Query: 841 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLE--PVSWREGPSGHSTLPRSPRDAP 898
+ P G + P P S P + + P P G P P+ P
Sbjct: 85 GGN-KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 143
Query: 899 CSASSELSGPSTP-LHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKA 957
++ GP P P QG +R +RSP P PP +
Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSR--SSRSPPGKPQG--------PPPQGGNQPQG 193
Query: 958 PELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSP--VPTTLPGLRHA 1015
P P G P P PP P PQ P G + S RSP P P
Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 1016 PWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPE 1075
QGP PP P G P P P P PQ P P S + S P P+
Sbjct: 252 QPQGPPPPPGKPQGPP--PQGGNKPQGPPPPGKPQGPP----PQGGSKSRSSRSPPGKPQ 305
Query: 1076 KRHLPGPGQQPG--PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPP 1122
GP Q G P GP +G P N PQ P PP
Sbjct: 306 -----GPPPQGGNQPQGPPPPPGKPQG-------PPPQGGNKPQGPPPP 342
Score = 69.3 bits (168), Expect = 2e-11
Identities = 91/343 (26%), Positives = 115/343 (33%), Gaps = 36/343 (10%)
Query: 800 PAYGRVPHSCGSPGEGRGYPSPG--AHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRY 857
P G P PG+ +G P G + SPR+ P PP PQ P G +
Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQG 141
Query: 858 PLP-GHLASAGPLASAESLEPVSWREGPSGHS-TLPRSPRDAPCSASSELSGPSTPLHTS 915
P P G GP + P + S S + P P+ P ++ GP P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201
Query: 916 S---PVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPS 972
P G + P P Q + ++ S G + P G+ P+ P
Sbjct: 202 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR--SPPGKPQGPPPQGGNQPQGPPPP 259
Query: 973 PVSPTFPPSSPSDWPQERSPGGHSDGASP----RSPVPTTLPGLRHAP-------WQGPR 1021
P P PP + PQ P G G P +S + PG P QGP
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319
Query: 1022 GPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPG 1081
PP P G P P P P PQ P P S + S P P+ G
Sbjct: 320 PPPGKPQGPP--PQGGNKPQGPPPPGKPQGPP----PQGGSKSRSARSPPGKPQ-----G 368
Query: 1082 PGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQ 1124
P QQ G P+ PA G P PQ P P Q
Sbjct: 369 PPQQEGN-NPQGPPPPAGGNPQQPQAPPA---GQPQGPPRPPQ 407
Score = 69.3 bits (168), Expect = 2e-11
Identities = 82/308 (26%), Positives = 107/308 (34%), Gaps = 29/308 (9%)
Query: 812 PGEGRGYPSPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPG----HLAS 865
PG+ +G P G + P+ PG P P PQ + P G + P P +S
Sbjct: 115 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP-QGPPPPGKPQGPPPQGDNKSRSS 173
Query: 866 AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTR 925
P + P + P G P P+ P ++ GP P P ++ +
Sbjct: 174 RSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN-K 231
Query: 926 RQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF--PPSSP 983
Q RSP P G P GK P G +P P P PP
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291
Query: 984 SDWPQERSPGGHSDGASPRS-------PVPTTLPGLRHAPWQG---PRGPPDSPDGSPLT 1033
S RSP G G P+ P P P + P QG P+GPP P G P
Sbjct: 292 SKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPP--PPGKPQG 347
Query: 1034 PVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPP--LPEKRHLPGPGQQPGPWGP 1091
P P ++ PP P P + G P P++ P GQ GP P
Sbjct: 348 PPPQGGSKSRSARSPPGKPQGP--PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405
Query: 1092 EQASSPAR 1099
Q P+R
Sbjct: 406 PQGGRPSR 413
Score = 60.8 bits (146), Expect = 9e-09
Identities = 79/277 (28%), Positives = 100/277 (36%), Gaps = 43/277 (15%)
Query: 869 LASAESL-EPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTP--LHTSSPVQGKESTR 925
L+SA++L E VS E PS + +P+ AP ++ GP +P P QG +
Sbjct: 13 LSSAQNLNEDVSQEESPS---LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQ 69
Query: 926 RQDTR--SPTSAPTQRLS-------PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSP 976
P P Q + PG+ P Q ++P P G P P
Sbjct: 70 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 129
Query: 977 TFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP------RGPPDSPDGS 1030
PP P PQ P G G P+ P P P + P QG R PP P G
Sbjct: 130 QGPPPPPGK-PQGPPPQG---GNKPQGPPPPGKP--QGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 1031 PLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1090
P P P P PP P P G ++P P PG Q P P G
Sbjct: 184 P--PQGGNQP---QGPPPPPGKPQGPPP-------QGGNKPQGPPP---PGKPQGPPPQG 228
Query: 1091 PEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQ 1127
++ S AR P N PQ P PP + Q
Sbjct: 229 DNKSQS-ARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 264
Score = 50.1 bits (118), Expect = 2e-05
Identities = 50/189 (26%), Positives = 67/189 (35%), Gaps = 20/189 (10%)
Query: 812 PGEGRGYPSPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPG----HLAS 865
PG+ +G P G + P+ PG P P PQ + P G + P P +S
Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP-QGPPPPGKPQGPPPQGGSKSRSS 297
Query: 866 AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPV-QGKEST 924
P + P + P G P P+ P ++ GP P P QG +
Sbjct: 298 RSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356
Query: 925 RRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE-PLAPSPVSPTFPPSSP 983
R RSP P PP + + P P+G P+ P AP P PP P
Sbjct: 357 R--SARSPPGKPQG--------PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 406
Query: 984 SDWPQERSP 992
R P
Sbjct: 407 QGGRPSRPP 415
Score = 32.0 bits (71), Expect = 4.3
Identities = 36/144 (25%), Positives = 48/144 (33%), Gaps = 11/144 (7%)
Query: 481 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE 540
SP + Q PP Q P PPPP G + P + G PPP +
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG-PPPQGDNKSR 171
Query: 541 LDRLLGGCGVA----SGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRP------GLSR 590
R G G + G + P GG G P +P G ++
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231
Query: 591 HCSCRQGYREPCGVPNGGYYRPEG 614
S R +P G P G +P+G
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQG 255
Score = 31.2 bits (69), Expect = 7.4
Identities = 35/143 (24%), Positives = 47/143 (32%), Gaps = 9/143 (6%)
Query: 481 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE 540
SP + Q PP Q P PPPP G + P + G PP ++ +
Sbjct: 237 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296
Query: 541 LDRLLG---GCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRP------GLSRH 591
G G G + G + P GG G P +P G S+
Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356
Query: 592 CSCRQGYREPCGVPNGGYYRPEG 614
S R +P G P P+G
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQG 379
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 72.8 bits (177), Expect = 2e-12
Identities = 188/771 (24%), Positives = 249/771 (32%), Gaps = 135/771 (17%)
Query: 501 PPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELD------------RLLGGC 548
P PP L + SG + PG P PT + + + LLG
Sbjct: 904 PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963
Query: 549 GVAS--------GGRGAGRETAILDDEEQPTVGGGPHLGVYPGHR--PGLSRHCSCRQGY 598
G G G + D QP + G P L PG + PGL + G
Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG----QPGL 1019
Query: 599 REPCG----VPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSE-GLYP 653
P G + + G+ P+G G G P + + +S GL
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGV--EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1077
Query: 654 YPPEMGKPATGDFGYRA-PGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLERE 712
P G+P G GY PG + V DPGLP L P + + LP
Sbjct: 1078 LPGPKGEP--GLPGYPGNPGIKGSV--GDPGLPGLPGTPGAKGQPGLPG-------FPGT 1126
Query: 713 AGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTM 772
G P +P PG P P+ GH P P GE+G G
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPV--GGGGHPGQPGPP---------GEKGKPGQDGIP 1175
Query: 773 CPEGRYGHPGYPALVTYSYGGAVPSYCPAY------GRVPHSCGSPGEGRGYPSPGAHSP 826
P G+ G PG P +G P P G +P G+PG PG H
Sbjct: 1176 GPAGQKGEPGQP-----GFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF 1230
Query: 827 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSG 886
PG P P P EG P P GP R GP+G
Sbjct: 1231 PGVQGPPGPPGSPG--------PALEGPKGNPGP-----QGP----------PGRPGPTG 1267
Query: 887 HSTL--PRSPRDAPCSA--SSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSP 942
L P P P + E P P P + +P +
Sbjct: 1268 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1327
Query: 943 GEALPPVSQAGTGKAPE-LPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP 1001
LP V K P +P +GPE P + P PP P P +S D P
Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPGSAGPEG-EPGLIGPPGPPGLPG--PSGQSIIIKGDAGPP 1384
Query: 1002 RSPVPTTLPGLRHAPW-QGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLA 1060
P PGL+ P QGP+G P P G P P + +P + P P
Sbjct: 1385 GIP---GQPGLKGLPGPQGPQGLP-GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP-- 1438
Query: 1061 ASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARG--ISHHVTFAPLLSDNVPQT 1118
T GL P PGP GP GP SS A G I+ H + + PQ
Sbjct: 1439 ---GTRGLDGP--------PGPDGLQGPPGPPGTSSVAHGFLITRHSQ-----TTDAPQC 1482
Query: 1119 PEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFL-IRDSHSFQGAYGLA 1177
P+ Q + +K + L + P F I + +F +
Sbjct: 1483 PQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYS 1542
Query: 1178 LKVATPPP---SAQPWKGDPVEQLVRHFLIETGP--------KGVKIKGCP 1217
++TP P S QP KG ++ + + P + ++I CP
Sbjct: 1543 YWLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCP 1593
Score = 55.5 bits (132), Expect = 4e-07
Identities = 93/346 (26%), Positives = 109/346 (31%), Gaps = 64/346 (18%)
Query: 757 PPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGR--------VPHS 808
P G +G G G G+PG P L G P P +G +
Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLP----GNIGPMGPPGFGPPGPVGEKGIQGV 639
Query: 809 CGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQS--RKLSYEIPTEEGGDRYPLPGHLASA 866
G+PG+ G P P P PG P P + R +P + G LPG
Sbjct: 640 AGNPGQP-GIPGPKG-DPGQTITQPGKPGLPGNPGRDGDVGLPGDPG-----LPGQPGLP 692
Query: 867 G-PLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTR 925
G P + E P GP G P P P A P TP
Sbjct: 693 GIPGSKGEPGIPGIGLPGPPGPKGFPGIP--GPPGA------PGTPGRIGL--------- 735
Query: 926 RQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSD 985
+ P P + PG ALP G P GP+ P PP P
Sbjct: 736 -EGPPGPPGFPGPKGEPGFALP--GPPGPPGLPGFKGALGPKGDRGFPG----PPGPPGR 788
Query: 986 WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS 1045
+ PG D P P PGL QGP GPP P G P +P
Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP-GPIGQPGLHGIPGEKGD 847
Query: 1046 PEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP 1091
P PP GL P P +R PG PGP GP
Sbjct: 848 PGPP-----------------GLDVPGPPGERGSPGIPGAPGPIGP 876
Score = 55.1 bits (131), Expect = 5e-07
Identities = 116/448 (25%), Positives = 145/448 (32%), Gaps = 104/448 (23%)
Query: 715 EGWASEAGKPLL--HPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTM 772
+G E G P L HP PG P P P P G++G +G
Sbjct: 44 KGEKGERGFPGLEGHPGLPGFPGP---------EGP--------PGPRGQKGDDGIPGPP 86
Query: 773 CPEGRYGHPGYPALVTYSYGGAVPSY--CPAYGRVPHSCGSPGEGRGYPS----PGAHSP 826
P+G G PG P +P + P +P G+ GE RG+P PG P
Sbjct: 87 GPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE-RGFPGSPGFPGLQGP 145
Query: 827 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYP-LPGHLASAGPLASAESLEPVS--WREG 883
PG P S +S +P +G YP PG GP + P G
Sbjct: 146 PGPPGIPGMKGEPGSIIMS-SLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204
Query: 884 PSGHSTLPRSPR-------DAPCSASSE--LSGPSTPLHTSSPVQGKESTRRQDT----- 929
P G LP P+ P E L GP P P Q E R D
Sbjct: 205 PPGPPGLP-GPKGNMGLNFQGPKGEKGEQGLQGPPGP-----PGQISEQKRPIDVEFQKG 258
Query: 930 -------RSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFP--P 980
R P P R PG + G P G + P P P P
Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318
Query: 981 SSPSDWPQERSPGGHSDGASPRSP---VPTT-------------LPGL------RHAPW- 1017
P + ++ G D P P +P LPGL R P
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378
Query: 1018 QGPRGPPDSPDGSPLTP-----VPSQM-------PWLVASPEPPQSSPTPAFPLAASYDT 1065
QGP G P P + + P P + P ++ P PP P P
Sbjct: 379 QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP------- 431
Query: 1066 NGLSQPPLPEKRHLPGPGQ--QPGPWGP 1091
GL PP P H+P + +PGP GP
Sbjct: 432 -GLPGPPGPAGPHIPPSDEICEPGPPGP 458
Score = 54.3 bits (129), Expect = 8e-07
Identities = 101/383 (26%), Positives = 131/383 (34%), Gaps = 70/383 (18%)
Query: 757 PPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGR 816
P + G +G +G +G G PG P LV G + +P G GE R
Sbjct: 321 PGEPGRDGEKG------QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE-R 373
Query: 817 GYPS----PGAHSPRAGSIS--PGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLA 870
G+P PG P ++ PG P +P R + GD P PG P
Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG--------QKGDEGP-PGISIPGPPGL 424
Query: 871 SAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSP----VQGKESTR- 925
+ P GP G P P P S E+ P P SP +QG++ +
Sbjct: 425 DGQPGAP--GLPGPPG----PAGPHIPP---SDEICEPGPPGPPGSPGDKGLQGEQGVKG 475
Query: 926 -RQDT------RSPTSAPTQRLSPGEALPPVSQAGTGKAPEL--PSGSGPEPLAP---SP 973
+ DT + P Q PG PP S G+ E +GP+ L +P
Sbjct: 476 DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAP 535
Query: 974 VSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQ-------GPRGPP-- 1024
+P FP S PG D SP LPGL P Q GP+G P
Sbjct: 536 GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595
Query: 1025 ---DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPG 1081
G P P +P + PP P P+ P P +PG
Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGVAGNPGQP---GIPG 650
Query: 1082 PGQQPG-----PWGPEQASSPAR 1099
P PG P P +P R
Sbjct: 651 PKGDPGQTITQPGKPGLPGNPGR 673
Score = 52.0 bits (123), Expect = 4e-06
Identities = 175/690 (25%), Positives = 223/690 (32%), Gaps = 133/690 (19%)
Query: 475 RGP--LDGSPYAQVQRPPRQTPPAPSPE-----PPPPPMLSVSSDSGHSSTLTTEPAAES 527
+GP L G P A V PP PP E PP +S+ G L +P A
Sbjct: 379 QGPPGLPGPPGAAVMGPPG--PPGFPGERGQKGDEGPPGISIPGPPG----LDGQPGAPG 432
Query: 528 -PGRPPPTAAERQELDRLLG----GCGVASGGRGAGRETAILDDEEQPTVGG-GPHLGVY 581
PG P P D + G + G +G E + D+ G +
Sbjct: 433 LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492
Query: 582 PGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKR 641
PG +PGL G+P P G+L + G +G +G A A+ K
Sbjct: 493 PG-QPGLP-------------GLPG-----PPGSL-----GFPGQKGE-KGQAGATGPKG 527
Query: 642 RLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYR-EVVILEDPGLPALYPCPACEEKLALP 700
+ G +P G+P GD PG + + L PG P L P + LP
Sbjct: 528 LPGIPGAPGAPGFPGSKGEP--GDI-LTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584
Query: 701 TAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKA 760
L G + E G + E G P G+P LP + PM P
Sbjct: 585 --GLPGPKGE-PGGITFKGERGPP-------GNPG---LPGLPGNIGPMGPPGFGPPGPV 631
Query: 761 GEEGHEGCS----------------YTMCPEGRYGHPGYPAL---VTYSYGGAVPSYCPA 801
GE+G +G + T+ G+ G PG P V +P P
Sbjct: 632 GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ-PG 690
Query: 802 YGRVPHSCGSPG-EGRGYPSP-------GAHSPRAGSISPG-----SPPYPQSRKLSYEI 848
+P S G PG G G P P G P +PG PP P
Sbjct: 691 LPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG------F 744
Query: 849 PTEEGGDRYPLPGHLASAGPLASAESLEPVSWR-----EGPSGHSTLPRSPRDAPCSASS 903
P +G + LPG G +L P R GP G + L P +
Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804
Query: 904 ELSGPSTPLHTSS-PVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPS 962
GP P VQG P P PGE P P
Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGP--PGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862
Query: 963 GSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD---GASPRSPVPTTLPGLRHAPW-- 1017
GS P AP P+ P P P PG + P P P +PG P
Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLK 922
Query: 1018 --QGPRGPPDSP--------DGSPLTPVP--SQMPWLVASPEPPQSSPTPAFP-LAASYD 1064
G +G P P G P P P P L+ S P P ++
Sbjct: 923 GDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG 982
Query: 1065 TNGL----SQPPLPEKRHLPGPGQQPGPWG 1090
GL QP L + LPGP PGP G
Sbjct: 983 YQGLPGDPGQPGLSGQPGLPGP---PGPKG 1009
Score = 45.4 bits (106), Expect = 4e-04
Identities = 84/335 (25%), Positives = 103/335 (30%), Gaps = 82/335 (24%)
Query: 782 GYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQS 841
G PA YG + S C G G GE RG+P H G P PP P+
Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIK----GEKGE-RGFPGLEGHPGLPGFPGPEGPPGPRG 75
Query: 842 RKLSYEIPTEEG--GDRYP--------------LPGHLASAGPLASAESLEPVSWREGPS 885
+K IP G G R P +PGH + GP + + G
Sbjct: 76 QKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-------QGIPGCNGTK 128
Query: 886 GHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEA 945
G P SP L GP P + G + S S P + +PG
Sbjct: 129 GERGFPGSP------GFPGLQGPPGP----PGIPGMKGEPGSIIMS--SLPGPKGNPGYP 176
Query: 946 LPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPV 1005
PP Q LP +G P P+ P P PG P P
Sbjct: 177 GPPGIQG-------LPGPTG----IPGPIGPPGP------------PGLMGPPGPPGLPG 213
Query: 1006 PTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDT 1065
P GL +QGP+G L P PP P+ +
Sbjct: 214 PKGNMGLN---FQGPKGEKGEQG-------------LQGPPGPPGQISEQKRPIDVEFQK 257
Query: 1066 NGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARG 1100
LP R PGP GP GP +G
Sbjct: 258 ---GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,023,841
Number of Sequences: 37866
Number of extensions: 5101127
Number of successful extensions: 45047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 359
Number of HSP's successfully gapped in prelim test: 2105
Number of HSP's that attempted gapping in prelim test: 21562
Number of HSP's gapped (non-prelim): 17585
length of query: 1409
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1294
effective length of database: 13,892,928
effective search space: 17977448832
effective search space used: 17977448832
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.