Guide to the Human Genome
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Name: TPTE Sequence: fasta or formatted (551aa) NCBI GI: 109689707
Description:

transmembrane phosphatase with tensin homology isoform alpha

Referenced in:

Inositol Pathways
Sodium Channels

Other entries for this name:
alt prot [533aa] transmembrane phosphatase with tensin homology isoform beta
alt prot [513aa] transmembrane phosphatase with tensin homology isoform gamma
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.7         26           2
 C cysteine            1.1          6           1
 D aspartate           6.4         35           2
 E glutamate           5.8         32           2
 F phenylalanine       6.9         38           2
 G glycine             3.1         17           2
 H histidine           3.1         17           1
 I isoleucine          8.2         45           2
 K lysine              6.2         34           2
 L leucine            10.7         59           3
 M methionine          1.6          9           1
 N asparagine          4.0         22           2
 P proline             3.8         21           2
 Q glutamine           2.5         14           2
 R arginine            6.9         38           3
 S serine              7.3         40           2
 T threonine           4.7         26           2
 V valine              7.8         43           2
 W tryptophan          0.7          4           1
 Y tyrosine            4.5         25           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transmembrane phosphatase with tensin homology isof... 
TPTE                  0.957   transmembrane phosphatase with tensin homology isofo...
TPTE                  0.900   transmembrane phosphatase with tensin homology isofo...
TPTE2                 0.831   TPTE and PTEN homologous inositol lipid phosphatase...
TPTE2                 0.666   TPTE and PTEN homologous inositol lipid phosphatase...
TPTE2                 0.553   TPTE and PTEN homologous inositol lipid phosphatase...
PTEN                  0.168   phosphatase and tensin homolog 
TNS1                  0.092   tensin 
TNS3                  0.090   tensin 3 
GAK                   0.087   cyclin G associated kinase 
TENC1                 0.077   tensin like C1 domain containing phosphatase isoform...
TENC1                 0.077   tensin like C1 domain containing phosphatase isoform...
TENC1                 0.077   tensin like C1 domain containing phosphatase isoform...
LOC100293174          0.073   PREDICTED: similar to transmembrane phosphoinositid...
DNAJC6                0.067   DnaJ (Hsp40) homolog, subfamily C, member 6 
HVCN1                 0.036   hydrogen voltage-gated channel 1 
HVCN1                 0.036   hydrogen voltage-gated channel 1 
SCN8A                 0.020   sodium channel, voltage gated, type VIII, alpha [Homo...
SLC9A10               0.019   sperm-specific sodium proton exchanger 
SCN4A                 0.017   voltage-gated sodium channel type 4 alpha 
CACNA1H               0.016   calcium channel, voltage-dependent, T type, alpha 1H...
DUSP11                0.016   dual specificity phosphatase 11 
CATSPER2              0.015   sperm-associated cation channel 2 isoform 2 
CATSPER2              0.015   sperm-associated cation channel 2 isoform 1 
CACNA1H               0.015   calcium channel, voltage-dependent, T type, alpha 1H...
CACNA1I               0.015   calcium channel, voltage-dependent, T type, alpha 1I...
CACNA1I               0.015   calcium channel, voltage-dependent, T type, alpha 1I...
PTPRB                 0.013   protein tyrosine phosphatase, receptor type, B isof...
PTPRB                 0.013   protein tyrosine phosphatase, receptor type, B isof...
SCN3A                 0.013   sodium channel, voltage-gated, type III, alpha isof...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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