Search of human proteins with 38787941

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38787941 tensin like C1 domain containing phosphatase
isoform 1 [Homo sapiens]
         (1419 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38787941 tensin like C1 domain containing phosphatase isoform...  2966   0.0  
gi|38787957 tensin like C1 domain containing phosphatase isoform...  2901   0.0  
gi|38787970 tensin like C1 domain containing phosphatase isoform...  2695   0.0  
gi|66529407 tensin [Homo sapiens]                                     499   e-141
gi|65288071 tensin 3 [Homo sapiens]                                   461   e-129
gi|157738639 tensin 4 [Homo sapiens]                                  301   3e-81
gi|73765544 phosphatase and tensin homolog [Homo sapiens]             129   2e-29
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap...   120   7e-27
gi|157384971 cyclin G associated kinase [Homo sapiens]                120   9e-27
gi|40549435 transmembrane phosphatase with tensin homology isofo...   108   5e-23
gi|40549433 transmembrane phosphatase with tensin homology isofo...   108   5e-23
gi|109689707 transmembrane phosphatase with tensin homology isof...   108   5e-23
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase...   100   2e-20
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase...   100   2e-20
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase...   100   2e-20
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             97   1e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    79   4e-14
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    79   4e-14
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    79   4e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    78   5e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    77   1e-13
gi|55750053 atrophin-1 [Homo sapiens]                                  76   2e-13
gi|55750041 atrophin-1 [Homo sapiens]                                  76   2e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni...    74   8e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   74   1e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   74   1e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   74   1e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    74   1e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     74   1e-12
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    73   2e-12

>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 2966 bits (7688), Expect = 0.0
 Identities = 1419/1419 (100%), Positives = 1419/1419 (100%)

Query: 1    MDGGGVCVGRGDLLSSPQALGQLLRKESRPRRAMKPRKAEPHSFREKVFRKKPPVCAVCK 60
            MDGGGVCVGRGDLLSSPQALGQLLRKESRPRRAMKPRKAEPHSFREKVFRKKPPVCAVCK
Sbjct: 1    MDGGGVCVGRGDLLSSPQALGQLLRKESRPRRAMKPRKAEPHSFREKVFRKKPPVCAVCK 60

Query: 61   VTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSK 120
            VTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSK
Sbjct: 61   VTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSK 120

Query: 121  QRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHR 180
            QRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHR
Sbjct: 121  QRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHR 180

Query: 181  DKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLY 240
            DKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLY
Sbjct: 181  DKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLY 240

Query: 241  CKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGL 300
            CKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGL
Sbjct: 241  CKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGL 300

Query: 301  LSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQL 360
            LSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQL
Sbjct: 301  LSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQL 360

Query: 361  CISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDE 420
            CISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDE
Sbjct: 361  CISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDE 420

Query: 421  RFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGS 480
            RFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGS
Sbjct: 421  RFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGS 480

Query: 481  LTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGR 540
            LTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGR
Sbjct: 481  LTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGR 540

Query: 541  PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSR 600
            PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSR
Sbjct: 541  PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSR 600

Query: 601  HCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEG 660
            HCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEG
Sbjct: 601  HCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEG 660

Query: 661  LYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLE 720
            LYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLE
Sbjct: 661  LYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLE 720

Query: 721  REAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSY 780
            REAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSY
Sbjct: 721  REAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSY 780

Query: 781  TMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGS 840
            TMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGS
Sbjct: 781  TMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGS 840

Query: 841  ISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL 900
            ISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL
Sbjct: 841  ISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL 900

Query: 901  PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVS 960
            PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVS
Sbjct: 901  PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVS 960

Query: 961  QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1020
            QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP
Sbjct: 961  QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1020

Query: 1021 GLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQ 1080
            GLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQ
Sbjct: 1021 GLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQ 1080

Query: 1081 PPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNV 1140
            PPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNV
Sbjct: 1081 PPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNV 1140

Query: 1141 KFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPW 1200
            KFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPW
Sbjct: 1141 KFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPW 1200

Query: 1201 KGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDP 1260
            KGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDP
Sbjct: 1201 KGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDP 1260

Query: 1261 LEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPT 1320
            LEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPT
Sbjct: 1261 LEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPT 1320

Query: 1321 PAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVA 1380
            PAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVA
Sbjct: 1321 PAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVA 1380

Query: 1381 KKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK 1419
            KKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
Sbjct: 1381 KKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK 1419


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 2901 bits (7521), Expect = 0.0
 Identities = 1388/1402 (99%), Positives = 1392/1402 (99%)

Query: 18   QALGQLLRKESRPRRAMKPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVAT 77
            + L + L +    R A +PRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVAT
Sbjct: 8    ERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVAT 67

Query: 78   HRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMER 137
            HRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMER
Sbjct: 68   HRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMER 127

Query: 138  RWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTR 197
            RWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTR
Sbjct: 128  RWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTR 187

Query: 198  LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
            LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH
Sbjct: 188  LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 247

Query: 258  YSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYV 317
            YSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYV
Sbjct: 248  YSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYV 307

Query: 318  LIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVT 377
            LIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVT
Sbjct: 308  LIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVT 367

Query: 378  CYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPE 437
            CYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPE
Sbjct: 368  CYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPE 427

Query: 438  KIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQ 497
            KIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQ
Sbjct: 428  KIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQ 487

Query: 498  RPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGG 557
            RPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGG
Sbjct: 488  RPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGG 547

Query: 558  CGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNG 617
            CGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNG
Sbjct: 548  CGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNG 607

Query: 618  GYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFG 677
            GYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFG
Sbjct: 608  GYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFG 667

Query: 678  YRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLH 737
            YRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLH
Sbjct: 668  YRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLH 727

Query: 738  PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV 797
            PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV
Sbjct: 728  PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV 787

Query: 798  TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE 857
            TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE
Sbjct: 788  TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE 847

Query: 858  IPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSG 917
            IPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSG
Sbjct: 848  IPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSG 907

Query: 918  PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE 977
            PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE
Sbjct: 908  PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE 967

Query: 978  PLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSP 1037
            PLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSP
Sbjct: 968  PLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSP 1027

Query: 1038 DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG 1097
            DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG
Sbjct: 1028 DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG 1087

Query: 1098 PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSR 1157
            PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSR
Sbjct: 1088 PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSR 1147

Query: 1158 DQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETG 1217
            DQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETG
Sbjct: 1148 DQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETG 1207

Query: 1218 PKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAA 1277
            PKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAA
Sbjct: 1208 PKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAA 1267

Query: 1278 DLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTD 1337
            DLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTD
Sbjct: 1268 DLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTD 1327

Query: 1338 NQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAEL 1397
            NQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAEL
Sbjct: 1328 NQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAEL 1387

Query: 1398 DPDQPAGAIVTFITKVLLGQRK 1419
            DPDQPAGAIVTFITKVLLGQRK
Sbjct: 1388 DPDQPAGAIVTFITKVLLGQRK 1409


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
            [Homo sapiens]
          Length = 1285

 Score = 2695 bits (6985), Expect = 0.0
 Identities = 1285/1285 (100%), Positives = 1285/1285 (100%)

Query: 135  MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 194
            MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD
Sbjct: 1    MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 60

Query: 195  LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 254
            LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA
Sbjct: 61   LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 120

Query: 255  YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 314
            YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL
Sbjct: 121  YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 180

Query: 315  HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 374
            HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV
Sbjct: 181  HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 240

Query: 375  MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 434
            MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS
Sbjct: 241  MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 300

Query: 435  SPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYA 494
            SPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYA
Sbjct: 301  SPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYA 360

Query: 495  QVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRL 554
            QVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRL
Sbjct: 361  QVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRL 420

Query: 555  LGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGV 614
            LGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGV
Sbjct: 421  LGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGV 480

Query: 615  PNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATG 674
            PNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATG
Sbjct: 481  PNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATG 540

Query: 675  DFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP 734
            DFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP
Sbjct: 541  DFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP 600

Query: 735  LLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYP 794
            LLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYP
Sbjct: 601  LLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYP 660

Query: 795  ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKL 854
            ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKL
Sbjct: 661  ALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKL 720

Query: 855  SYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSE 914
            SYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSE
Sbjct: 721  SYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSE 780

Query: 915  LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGS 974
            LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGS
Sbjct: 781  LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGS 840

Query: 975  GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP 1034
            GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP
Sbjct: 841  GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPP 900

Query: 1035 DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQ 1094
            DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQ
Sbjct: 901  DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQ 960

Query: 1095 QPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPH 1154
            QPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPH
Sbjct: 961  QPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPH 1020

Query: 1155 LSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLI 1214
            LSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLI
Sbjct: 1021 LSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLI 1080

Query: 1215 ETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMS 1274
            ETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMS
Sbjct: 1081 ETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMS 1140

Query: 1275 TAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGIT 1334
            TAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGIT
Sbjct: 1141 TAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGIT 1200

Query: 1335 LTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLF 1394
            LTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLF
Sbjct: 1201 LTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLF 1260

Query: 1395 AELDPDQPAGAIVTFITKVLLGQRK 1419
            AELDPDQPAGAIVTFITKVLLGQRK
Sbjct: 1261 AELDPDQPAGAIVTFITKVLLGQRK 1285


>gi|66529407 tensin [Homo sapiens]
          Length = 1735

 Score =  499 bits (1285), Expect = e-141
 Identities = 367/1022 (35%), Positives = 499/1022 (48%), Gaps = 145/1022 (14%)

Query: 130  SLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLS 189
            S+   ME   +LDL YVTERI+A +FP+  +E+  R +LRE+A +L+SKH   YLLFNLS
Sbjct: 2    SVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLS 61

Query: 190  EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLG 249
            E+R D+T+L+ KV +FGWP+LH P L+K+CSICKAM+TWL+ADP +VVVL+ KGN+G++G
Sbjct: 62   ERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIG 121

Query: 250  VIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNS 309
            V+++AYMHYS ISA ADQAL    M++F EDK+    QPSQRRY+ YFSGLLSGSI+MN+
Sbjct: 122  VVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNN 181

Query: 310  SPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALL 369
             PLFLH+V++  +P FE   G +PFL+IYQ+MQ VYTSG+Y+I G     +CI++EP LL
Sbjct: 182  KPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLL 241

Query: 370  LKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVE 429
            LKGD+++ CYHK  R   R ++FRVQFHTC IH   + F K+ LD+A+ D+RFP    VE
Sbjct: 242  LKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVE 301

Query: 430  FVFSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPL 488
            FVFS  PEKI+G     N PSVSVDYNT++P +RWDSY+NF+ H +D ++  + HT+GPL
Sbjct: 302  FVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPL 361

Query: 489  DGSPYAQVQRPP---------RQTPPAPSPEP-PPPPMLSVSSDSGHS--STLTTEPAAE 536
            DGS YA+V++             T P  S  P      LSVSSDSG+S  ST T +    
Sbjct: 362  DGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEP 421

Query: 537  SPGRPPPTAA----ERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYP 592
             PG    TAA    E++ELDRLL G G+    +GA   T  L    +P  G         
Sbjct: 422  VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHL--RSRPAGGSAV------ 473

Query: 593  GHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRR 652
               P   RH    Q +       NGG    E   +         +G   G +  ++    
Sbjct: 474  ---PSSGRHVVPAQVH------VNGGALASERETDILDDELPNQDGHSAG-SMGTLSSLD 523

Query: 653  LCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTA 712
               + SEG Y   PE   P T                   GL   YP             
Sbjct: 524  GVTNTSEGGY---PEALSPLTN------------------GLDKSYPM------------ 550

Query: 713  ALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGE 772
                        E   +  G P     R G       PA   H APM      +P  + +
Sbjct: 551  ------------EPMVNGGGYPYESASRAG-------PAHAGHTAPM------RPSYSAQ 585

Query: 773  EGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPG 832
            EG  G       EG   HP +P  VT S+    PS     G       S  E +  P+P 
Sbjct: 586  EGLAGYQ----REG--PHPAWPQPVTTSHYAHDPS-----GMFRSQSFSEAEPQLPPAPV 634

Query: 833  AHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWRE 892
                   ++  G   + Q ++   +        R     HL S   +AS  S +P++   
Sbjct: 635  RGGSSREAVQRGLNSWQQQQQQQQQ---PRPPPRQQERAHLESL--VASRPSPQPLAETP 689

Query: 893  GPSGHSTLPRSPRDAP-------------CSASSELSGPSTPLHTSSPVQGKESTRRQDT 939
             PS    LP  PR A                   E +  + PLH S  V G        +
Sbjct: 690  IPS----LPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLS 745

Query: 940  RSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 999
              P S  +++        P++Q+ +G  P   S   PEP   + +    P  S S +  +
Sbjct: 746  SQPLSGSSRQSH------PLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQ 799

Query: 1000 RSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASP 1056
                G +     +SP  ++LP      H+P  GP+ PP S  G    P+ S         
Sbjct: 800  PCLAGPNQDFHSKSPASSSLPAFLPTTHSP-PGPQQPPASLPGLTAQPLLSPKEATSDPS 858

Query: 1057 EPPQSSPTPAFPLAASYDTNGL-------SQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1109
              P+  P     L A +   G+       ++PP P +R     GQ      PE  S  + 
Sbjct: 859  RTPEEEPLNLEGLVA-HRVAGVQAREKQPAEPPAPLRRRAASDGQYENQ-SPEATSPRSP 916

Query: 1110 GI 1111
            G+
Sbjct: 917  GV 918



 Score =  412 bits (1060), Expect = e-115
 Identities = 380/1143 (33%), Positives = 504/1143 (44%), Gaps = 257/1143 (22%)

Query: 490  GSPYAQVQRP----PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP--GRPP- 542
            GS    VQR      +Q      P PPP        +S  +S  + +P AE+P    P  
Sbjct: 637  GSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEF 696

Query: 543  PTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHC 602
            P AA +QE+++ +    +           A L   +          G +PG  P  S+  
Sbjct: 697  PRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVP-------GAWPGASPLSSQPL 749

Query: 603  SCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLY 662
            S       P      GY           +  G   G+P+    AS+E     RS S   Y
Sbjct: 750  SGSSRQSHPLTQSRSGY-----------IPSGHSLGTPEPAPRASLESVPPGRSYSP--Y 796

Query: 663  PYPPEMGKPATGDFGYRAPGYREVVILED---------------PGL---PALYPCPACE 704
             Y P +  P   DF  ++P    +                    PGL   P L P  A  
Sbjct: 797  DYQPCLAGP-NQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATS 855

Query: 705  EKLALPTAA---LYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPD 761
            +    P      L GL   R AG     +       P  P  PL     + G +    P+
Sbjct: 856  DPSRTPEEEPLNLEGLVAHRVAGVQAREK------QPAEPPAPLRRRAASDGQYENQSPE 909

Query: 762  YSCLKPPKAGEEGHEGC-------SYTMCPEGRYGHPGYPALVTYSYG-----GAVPSYC 809
             +  + P  G      C       +  + P GR   P  P L +Y        G  PS  
Sbjct: 910  ATSPRSP--GVRSPVQCVSPELALTIALNPGGR---PKEPHLHSYKEAFEEMEGTSPSSP 964

Query: 810  P----------------AYGRVPHSCGS--------------------------PGEGRG 827
            P                A G  PH+                               E R 
Sbjct: 965  PPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRS 1024

Query: 828  YPSPGAHS----PRAGSISPGSPPYPQSRKLSYEIPTEEG--GDRYPLPGHLASAGPLAS 881
            Y    A +    PRA    P S   P ++   +EIP   G  G  +  P  L+++ P+ S
Sbjct: 1025 YVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILS 1084

Query: 882  AESLEPVSWREGPSGHSTLPRSPRDAPCSA---SSELSGPS----------TPLHT---- 924
            A+S    S+  G S     PR+P      +   S  L  PS          +PL T    
Sbjct: 1085 ADSTSVGSFPSGESSDQG-PRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSS 1143

Query: 925  -SSP---VQGKESTRRQDTRS----------PTSAPTQRLSPGEALPPVSQAG------T 964
             SSP   +Q   S+     R+          P S   +  + G   PP    G      +
Sbjct: 1144 YSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPS 1203

Query: 965  GKAPELPSGSGPEPLAP-------------------SPVSPTF----------------- 988
              AP  PS S  + + P                   +P SP+                  
Sbjct: 1204 MAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKV 1263

Query: 989  --PPSSPSDWPQERSPGGHSDG----------ASPRSPV--------PTTLPGL----RH 1024
               P SPS     R PG H             ASP SP          + +PG     RH
Sbjct: 1264 ATTPGSPS---LGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRH 1320

Query: 1025 APWQGPRGPPD---------SPDG--SPLTPV----PSQMPWL---VASPEPP-----QS 1061
              + G   P D         S  G  +P TP     P+  P L     SP P      Q 
Sbjct: 1321 VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQG 1380

Query: 1062 SPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLL 1121
            SPTPA P        G     LP    + G    P   G    SSP+ G +  V+F+  L
Sbjct: 1381 SPTPALPEKRRMSV-GDRAGSLPNYATINGKVSSPVASG---MSSPSGGST--VSFSHTL 1434

Query: 1122 SDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQ 1181
             D    +    + E+++ VKFVQDTSK+WYKP +SR+QAIALLKD++PGAF+IRDSHSF+
Sbjct: 1435 PDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFR 1494

Query: 1182 GAYGLALKVATPPPSA--QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALV 1239
            GAYGLA+KV++PPP+   Q  KGD   +LVRHFLIETGP+GVK+KGCP+EP FGSLSALV
Sbjct: 1495 GAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALV 1554

Query: 1240 SQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESL 1299
             QHSI P++LPC L IP++DP +E+ ++  P N  + ADLL+QGAAC+VL++ SV+ ESL
Sbjct: 1555 YQHSIIPLALPCKLVIPNRDPTDESKDSSGPAN--STADLLKQGAACNVLFVNSVDMESL 1612

Query: 1300 TGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTD 1359
            TGPQA+++A+S  L+  P P   +VHFKVSAQGITLTDNQRKLFFRRHYP+N++TF   D
Sbjct: 1613 TGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLD 1672

Query: 1360 PQDRRWTNPD-GTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLL--G 1416
            PQ+R+W   + G  +K+FGFVA+K GS  +N CHLFAELDP+QPA AIV F++KV+L  G
Sbjct: 1673 PQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAG 1732

Query: 1417 QRK 1419
            Q++
Sbjct: 1733 QKR 1735



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 98/406 (24%), Positives = 139/406 (34%), Gaps = 63/406 (15%)

Query: 891  REGPSGHSTLPRSPRDAPCSASSELSGPSTP-------LHTSSPVQGKESTRRQDTRSPT 943
            R  P+G S +P S R     A   ++G +         L    P Q   S     T S  
Sbjct: 464  RSRPAGGSAVPSSGRHV-VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSL 522

Query: 944  SAPTQRLSPG--EALPPVSQAGTGKAPELP--SGSGPEPLAPSPVSPTFP----PSSPSD 995
               T     G  EAL P++       P  P  +G G    + S   P       P  PS 
Sbjct: 523  DGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSY 582

Query: 996  WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS 1055
              QE   G   +G  P  P P T     H     P G   S   S   P   Q+P     
Sbjct: 583  SAQEGLAGYQREGPHPAWPQPVTTSHYAH----DPSGMFRSQSFSEAEP---QLP----- 630

Query: 1056 PEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHV 1115
            P P +   +     A     N   Q    +++  P P QQ      E+A   +  ++   
Sbjct: 631  PAPVRGGSSRE---AVQRGLNSWQQQQQQQQQPRPPPRQQ------ERAHLESL-VASRP 680

Query: 1116 TFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPG--AFL 1173
            +  PL    +P  PE P   SQ  ++   +T                L+ D +P   A  
Sbjct: 681  SPQPLAETPIPSLPEFPRAASQQEIEQSIETLNM-------------LMLDLEPASAAAP 727

Query: 1174 IRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFG 1233
            +  S S  GA+  A  +++ P S    +  P+ Q    ++    P G  + G P      
Sbjct: 728  LHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYI----PSGHSL-GTPEPAPRA 782

Query: 1234 SLSALVSQHSISPISLPCCLRIP-----SKDPLEETPEAPVPTNMS 1274
            SL ++    S SP     CL  P     SK P   +  A +PT  S
Sbjct: 783  SLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHS 828


>gi|65288071 tensin 3 [Homo sapiens]
          Length = 1445

 Score =  461 bits (1185), Expect = e-129
 Identities = 232/444 (52%), Positives = 310/444 (69%), Gaps = 20/444 (4%)

Query: 135 MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 194
           ME    LDLTY+TERI+A +FPA   E+ +  +L+E+  +L+SKH D YL+ NLSEKR+D
Sbjct: 1   MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60

Query: 195 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 254
           LT+LNPK+ D GWPELHAPPLDK+C+ICKA E+WL+++ QHVVV++C+G KG++GV++S+
Sbjct: 61  LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120

Query: 255 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 314
           YMH++ +SA ADQAL    M+KF +DKV+  +QPSQ+RY+ + SGLLSGS++MN+SPLFL
Sbjct: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180

Query: 315 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 374
           H+V++   P F+ G   +PFLK+YQ+MQ VYTSG+Y++    P ++CI +EPA LLKGDV
Sbjct: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240

Query: 375 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 434
           MV CYHK  R   R ++FR+QFHT  + G  L F K+ LD A  D+RFP    VE VFS+
Sbjct: 241 MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300

Query: 435 SPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPY 493
           +PEKI+GS    ND  V VDYNTT+P +RWDSYEN       S DG + HT+GP+DGS Y
Sbjct: 301 TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENL------SADGEVLHTQGPVDGSLY 354

Query: 494 AQVQRPPRQTPPAP-SPEPPPPP--------MLSVSSDSGHSSTLTTEPAAE---SPG-R 540
           A+V++     P  P  P+  P           LSVSSDSGHS+        E   +PG R
Sbjct: 355 AKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTR 414

Query: 541 PPPTAAERQELDRLLGGCGVASGG 564
              +A E+ ELD+LL G G+   G
Sbjct: 415 RGLSAQEKAELDQLLSGFGLEDPG 438



 Score =  412 bits (1058), Expect = e-114
 Identities = 265/594 (44%), Positives = 337/594 (56%), Gaps = 67/594 (11%)

Query: 868  PLPGHLASAGPLASAESL-EPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTS 925
            P   H     P +  E+L   V   E P G  ST+ R+   +  S     +   T + ++
Sbjct: 875  PASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCT-ISSN 933

Query: 926  SPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELP-SGSGPEPLAPSPV 984
             P Q +ES+   + +   S+P          P VS  G+G+    P S         SPV
Sbjct: 934  GPGQRRESSSSAERQWVESSPK---------PMVSLLGSGRPTGSPLSAEFSGTRKDSPV 984

Query: 985  SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTP 1044
               FPPS       E     HS   S   P  +  P       Q   G   +P GS L P
Sbjct: 985  LSCFPPS-------ELQAPFHSHELSLAEPPDSLAPPSS----QAFLGFGTAPVGSGLPP 1033

Query: 1045 VPSQMPWLVASPEPPQSSPTPAFPLAA---------------------SYDTNGLS---- 1079
                +  L+A+     +SPTP+ PL A                     S+ + GL     
Sbjct: 1034 -EEDLGALLANSHG--ASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGV 1090

Query: 1080 ----QPPLPEKRHLPGPGQQPGPWGPEQA--SSPARGISHHVTFAPLLSD-NVPQTPEPP 1132
                QPPLPEK+      +  G   P  +  SSP  G +  + F  +L D +       P
Sbjct: 1091 TLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150

Query: 1133 TQESQSN----VKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLAL 1188
              +S  +    VKFVQDTSKFWYK  +SR+QAIA+LKDK+PG+F++RDSHSF+GAYGLA+
Sbjct: 1151 LPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAM 1210

Query: 1189 KVATPPPSAQPWK---GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSIS 1245
            KVATPPPS        GD   +LVRHFLIE  PKGV++KGC +EPYFGSL+ALV QHSI+
Sbjct: 1211 KVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSIT 1270

Query: 1246 PISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1305
            P++LPC L IP +DPLEE  E+   T  ++AA+LL+QGAAC+V YL SVE ESLTG QA+
Sbjct: 1271 PLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAI 1330

Query: 1306 ARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRW 1365
             +A S  L   P P   VVHFKVSAQGITLTDNQRKLFFRRHYPVNS+ F + DPQDR+W
Sbjct: 1331 QKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKW 1390

Query: 1366 TNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK 1419
               DG +SK+FGFVA+K GS  +NVCHLFAE DP+QPA AIV F++KV++G  K
Sbjct: 1391 IK-DGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPK 1443



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 57/210 (27%), Positives = 79/210 (37%), Gaps = 31/210 (14%)

Query: 842  SPGSPPYP------QSRKLSYEI-PTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 894
            SPGSP         Q  +L  E+ PT E     P+P H+ + G  A+  S+ P S   G 
Sbjct: 687  SPGSPTLDIDQSIEQLNRLILELDPTFE-----PIPTHMNALGSQANG-SVSPDSVGGGL 740

Query: 895  SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 954
               S LP +      +   + S    PL        K S  + D  +    P  + + G+
Sbjct: 741  RASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR---KLSLGQYDNDAGGQLPFSKCAWGK 797

Query: 955  ALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWP---QERSPGGHSDGASP 1011
            A       G   AP LP    P P +P+ V  T  P  P D             S  ++P
Sbjct: 798  A-------GVDYAPNLP----PFP-SPADVKETMTPGYPQDLDIIDGRILSSKESMCSTP 845

Query: 1012 RSPVPTTLPGLRHAPWQGPRGPPDSPDGSP 1041
              PV    P ++ A    P  PP+ P  SP
Sbjct: 846  AFPVSPETPYVKTALRHPPFSPPEPPLSSP 875



 Score = 35.4 bits (80), Expect = 0.39
 Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 20/179 (11%)

Query: 813 GRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGH 872
           G  P     P  G G   P       GS  P   P P  RK S     +  G        
Sbjct: 530 GEDPQGTLVPDLGLGMDGPYERERTFGSREP-KQPQPLLRKPSVSAQMQAYGQ-----SS 583

Query: 873 LASAGPLASAESLEPVSWREGPSGHSTL-PRSPRDAPCSASSELSGPSTPLHTSSPVQGK 931
            ++   +   + +    +   P G + L  R P D P    ++   P TP   +S    +
Sbjct: 584 YSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTS---SR 640

Query: 932 ESTRRQDTRSPTSAPTQRLSPGEALP---PVSQAGTGKAPELPSGSGPEPLAPSPVSPT 987
            + +R     P    TQ+ SP +A     P  Q   G  PEL +G       PSP SPT
Sbjct: 641 VAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTG-------PSPGSPT 692


>gi|157738639 tensin 4 [Homo sapiens]
          Length = 715

 Score =  301 bits (771), Expect = 3e-81
 Identities = 195/492 (39%), Positives = 262/492 (53%), Gaps = 38/492 (7%)

Query: 941  SPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPT----------FPP 990
            S  S+P    SP  A P + +   G AP+   GS    L+ SPVS               
Sbjct: 238  SKASSPHGLGSPLVASPRLEKRLGGLAPQ--RGSRISVLSASPVSDVSYMFGSSQSLLHS 295

Query: 991  SSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMP 1050
            S+ S     RS    ++ +S    + +     R + +Q PR P  +  G P TP    + 
Sbjct: 296  SNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTM-GQPRTPHSPPLA 354

Query: 1051 WLVASPEPPQSSPTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQ--QPGPWGPEQASSP 1107
               AS  PP  + +    P+      NG  +P     +  PG     QPG   P      
Sbjct: 355  KEHASSCPPSITNSMVDIPIVL---INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPA 411

Query: 1108 ARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDK 1167
             R  S  ++ AP  +      PE P ++ Q  +KFV DTSK+W+KP+++R+QAI LL+ +
Sbjct: 412  TRSNSQTLSDAPFTT-----CPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKE 466

Query: 1168 DPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCP 1227
            +PGAF+IRDS S++G++GLALKV   P SAQ   G+    L+RHFLIE+  KGV +KG  
Sbjct: 467  EPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGAD 526

Query: 1228 SEPYFGSLSALVSQHSISPISLPCCLRIPSK-----DPLEETPEAPVPTNMSTAADLLRQ 1282
             EPYFGSLSA V QHSI  ++LPC L IP +     D   ++ ++P        A   ++
Sbjct: 527  EEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSP--------ASCQKK 578

Query: 1283 GAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKL 1342
             A C  LYL+SV  E+LTG  AV +A S        PTP VVHFKV+ QGITLTD QRK+
Sbjct: 579  SAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKV 638

Query: 1343 FFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQP 1402
            FFRRHYP+ ++ F   DP+ R+W       S IFGFVAK    P ENVCHLFAE D  QP
Sbjct: 639  FFRRHYPLTTLRFCGMDPEQRKW-QKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQP 697

Query: 1403 AGAIVTFITKVL 1414
            A  ++  +T +L
Sbjct: 698  ASQVIGLVTALL 709


>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
          Length = 403

 Score =  129 bits (325), Expect = 2e-29
 Identities = 83/279 (29%), Positives = 138/279 (49%), Gaps = 11/279 (3%)

Query: 136 ERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRH-D 194
           E  +DLDLTY+   I+A  FPA   E  +R ++ ++   L SKH++ Y ++NL  +RH D
Sbjct: 18  EDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYD 77

Query: 195 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 254
             + N +V  + + + + P L+ +   C+ ++ WLS D  HV  ++CK  KG+ GV++ A
Sbjct: 78  TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICA 137

Query: 255 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 314
           Y+ +      A +AL      +  + K  T   PSQRRY+ Y+S LL   +      L  
Sbjct: 138 YLLHRGKFLKAQEALDFYGEVRTRDKKGVT--IPSQRRYVYYYSYLLKNHLDYRPVALLF 195

Query: 315 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQ---LCISLEPALLLK 371
           H ++   +P F  GT   P   + Q    +Y+S     +GP  ++   +       L + 
Sbjct: 196 HKMMFETIPMFSGGT-CNPQFVVCQLKVKIYSSN----SGPTRREDKFMYFEFPQPLPVC 250

Query: 372 GDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPK 410
           GD+ V  +HK  +   +  +F    +T  I GP+ T  K
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289


>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
           sapiens]
          Length = 913

 Score =  120 bits (302), Expect = 7e-27
 Identities = 93/353 (26%), Positives = 166/353 (47%), Gaps = 28/353 (7%)

Query: 140 DLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLN 199
           DLD TYVT RI+  +FP    +   R  + ++   L S+H D Y ++NLS K +   + +
Sbjct: 63  DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122

Query: 200 PKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYS 259
            +V +  WP   AP L  L ++C+ M  WL  +P++V V++C   +    ++V A   + 
Sbjct: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182

Query: 260 KISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGS-IRMNSSPLFLHYVL 318
            + +    A+  L  +     +    L PS RRY+ Y   LL+    R +  PL +  + 
Sbjct: 183 NLYSTPGPAIRLLYAK-----RPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSIT 237

Query: 319 IPMLPAF-EPGTGFQPFLKIYQSMQLVYT--SGVYHIAGPGPQQLCISLEPALLLKGDVM 375
           +  +P F +   G +P+  +      +Y+  +    +     Q   I +   + ++GDV+
Sbjct: 238 VSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVV 297

Query: 376 VTCYHK----GGR---GTDRTLVFRVQFHT--CTIHGPQLTFPKDQLDEAWTDERFP--F 424
           V+ YH     G R       T +F++QFHT    +    L F K +LD     E++P  F
Sbjct: 298 VSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLF 357

Query: 425 QASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSV 477
           Q +++ V     +K+   TP  +   + D N   P++ + S+    Q H+D++
Sbjct: 358 QVTLD-VELQPHDKVIDLTPPWEHYCTKDVN---PSILFSSH----QEHQDTL 402



 Score = 38.5 bits (88), Expect = 0.046
 Identities = 69/326 (21%), Positives = 104/326 (31%), Gaps = 62/326 (19%)

Query: 823  GEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASA 882
            G   G    G   P      P +PP P+   L   +      + +  P     A P  ++
Sbjct: 468  GNANGDKPHGVKKPSKKQQEPAAPPPPEDVDL-LGLEGSAMSNSFSPP-----AAPPTNS 521

Query: 883  ESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 942
            E L  +    G +G       P  A  S   ++  PS P  T       +ST R+   S 
Sbjct: 522  ELLSDLFGGGGAAG-------PTQAGQSGVEDVFHPSGPAST-------QSTPRRSATST 567

Query: 943  TSAPTQRLSPGEALPP----------------VSQAGTGKAPELPSGSGPEPLAPSPVSP 986
            +++PT R+  G    P                ++ +     P L     P P   +  +P
Sbjct: 568  SASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTP 627

Query: 987  --TFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPD------ 1038
                 P     W     PGG   G+   +  PT   G  H      +  P + D      
Sbjct: 628  AVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT---GSSHGT-PTHQSKPQTLDPFADLG 683

Query: 1039 --GSPLTPVPSQMPWLVASPEPPQSSPTPAF--PLAASYDTNGLSQPPLPEKRHLPGPGQ 1094
              GS         P  +    PP SSP  A   P+   +   G      P          
Sbjct: 684  TLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQP---------- 733

Query: 1095 QPGPWGPEQASSPARGISHHVTFAPL 1120
            QP P      SSP    +++V+F+ +
Sbjct: 734  QPKPQPSMPHSSPQNRPNYNVSFSAM 759


>gi|157384971 cyclin G associated kinase [Homo sapiens]
          Length = 1311

 Score =  120 bits (301), Expect = 9e-27
 Identities = 84/305 (27%), Positives = 156/305 (51%), Gaps = 20/305 (6%)

Query: 140 DLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLN 199
           DLD++Y+T RI   +FPA   E   + ++ ++   L SKH   Y ++NLS + +  +R +
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFH 466

Query: 200 PKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYS 259
            +V + GW    AP L  L +IC+ M  WL  D ++V V++C   +    V V +++ + 
Sbjct: 467 NRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFC 526

Query: 260 KISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGS-IRMNSSPLFLHYVL 318
           ++ + A+ A+   +M+     +    + PS +RYI Y   +++   I  +S P+ +  V+
Sbjct: 527 RLFSTAEAAVYMFSMK-----RCPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVV 581

Query: 319 IPMLPAF-EPGTGFQPFLKIYQSMQLV-YTSGVYHIAGPGPQQLCISLEP-ALLLKGDVM 375
           +  +P F +  +G +PF ++Y   + V  TS  Y        +   ++ P  + ++GDV+
Sbjct: 582 MTPVPLFSKQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVL 641

Query: 376 VTCYHK----GGRGTDRTL---VFRVQFHTCTI--HGPQLTFPKDQLDEAWTDERFP--F 424
           +  YH     GGR   +     +F++QFHT  +  +   + F K  LD     E++P  F
Sbjct: 642 IVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLF 701

Query: 425 QASVE 429
           Q ++E
Sbjct: 702 QVNLE 706



 Score = 35.0 bits (79), Expect = 0.51
 Identities = 63/237 (26%), Positives = 88/237 (37%), Gaps = 33/237 (13%)

Query: 886  EPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSA 945
            +P S  +  +G  +    P D+    SS     S  LHT    + KE+    +  S   +
Sbjct: 757  QPGSTAQYDAGAGSPEAEPTDSDSPPSSSADA-SRFLHTLDWQEEKEAETGAENASSKES 815

Query: 946  PTQRLSPGEALPPVSQAGTGKAPE-LPSGSGPEP--LAPSPVSPTF------PPSSPSDW 996
             +  +   +      + G+  + E     + PEP  LA   V          P   P   
Sbjct: 816  ESALMEDRDESEVSDEGGSPISSEGQEPRADPEPPGLAAGLVQQDLVFEVETPAVLPEPV 875

Query: 997  PQERSP---GGHSD-GASPRSPVPTTLPGLRHAPWQGPR------GPPDSPDGSPLTPVP 1046
            PQE      G HS+ GA P  P     P    AP           GPP++    P   + 
Sbjct: 876  PQEDGVDLLGLHSEVGAGPAVP-----PQACKAPSSNTDLLSCLLGPPEAASQGPPEDLL 930

Query: 1047 SQMPWLVASPEPP---QSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1100
            S+ P L+ASP PP   QS+P    P AA  D  G   P LP   +   P   P  +G
Sbjct: 931  SEDPLLLASPAPPLSVQSTPRGGPPAAA--DPFG---PLLPSSGNNSQPCSNPDLFG 982



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 62/263 (23%), Positives = 85/263 (32%), Gaps = 50/263 (19%)

Query: 870  PGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQ 929
            P  L S  PL  A    P+S +  P G       P      +S   S P      S+P  
Sbjct: 926  PEDLLSEDPLLLASPAPPLSVQSTPRGGPPAAADPFGPLLPSSGNNSQPC-----SNPDL 980

Query: 930  GKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFP 989
              E         P S P+   +P    PP   A      +LP    P  +  S  +P   
Sbjct: 981  FGEFLNSDSVTVPPSFPSAHSAP----PPSCSADFLHLGDLPGE--PSKMTASSSNPDLL 1034

Query: 990  PSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQM 1049
                + W +          AS  +P P T             GP  SP G P  P  SQ 
Sbjct: 1035 GGWAA-WTET--------AASAVAPTPAT------------EGPLFSPGGQP-APCGSQA 1072

Query: 1050 PWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1109
             W  +       +P P   L     ++GL   P          G  PG + P+ A++P  
Sbjct: 1073 SWTKSQ------NPDPFADLGDL--SSGLQGSPA---------GFPPGGFIPKTATTPKG 1115

Query: 1110 GISHHVTFAPLLSDNVPQTPEPP 1132
              S   +  P    + P   +PP
Sbjct: 1116 SSSWQTSRPPAQGASWPPQAKPP 1138



 Score = 31.2 bits (69), Expect = 7.4
 Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 6/98 (6%)

Query: 479  GSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP 538
            G +  T     GS   Q  RPP Q    P P+  PPP         ++S  +   A E  
Sbjct: 1104 GFIPKTATTPKGSSSWQTSRPPAQGASWP-PQAKPPPKACTQPRPNYASNFSVIGAREER 1162

Query: 539  GRPPPTAAER-----QELDRLLGGCGVASGGRGAGRET 571
            G   P+ A++      + + LL   G +S     G +T
Sbjct: 1163 GVRAPSFAQKPKVSENDFEDLLSNQGFSSRSDKKGPKT 1200


>gi|40549435 transmembrane phosphatase with tensin homology isoform
           gamma [Homo sapiens]
          Length = 513

 Score =  108 bits (269), Expect = 5e-23
 Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)

Query: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
           +DLDLTYVTERI+A +FP+   +  +R  ++E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 197 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 256

Query: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
            + +V      + + P L ++    K +  W++ D +++V ++CKG   + G +V A++ 
Sbjct: 257 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 316

Query: 258 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 311
            S+I + A ++L     R+   DK  +E       PSQ+RY++YF+  +      N  P 
Sbjct: 317 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 373

Query: 312 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 366
             LF+ + +I  +P +      Q  ++   ++ ++ L   S + +I      ++ I +  
Sbjct: 374 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 430

Query: 367 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 423
            L L  DV V  ++           F    HT  I   +L  PK++LD     +    +P
Sbjct: 431 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 490

Query: 424 FQASVEFVFS---SSPEKIKGS 442
              +VE +F    +S + + GS
Sbjct: 491 SDFAVEILFGEKMTSSDVVAGS 512


>gi|40549433 transmembrane phosphatase with tensin homology isoform
           beta [Homo sapiens]
          Length = 533

 Score =  108 bits (269), Expect = 5e-23
 Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)

Query: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
           +DLDLTYVTERI+A +FP+   +  +R  ++E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 217 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 276

Query: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
            + +V      + + P L ++    K +  W++ D +++V ++CKG   + G +V A++ 
Sbjct: 277 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 336

Query: 258 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 311
            S+I + A ++L     R+   DK  +E       PSQ+RY++YF+  +      N  P 
Sbjct: 337 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 393

Query: 312 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 366
             LF+ + +I  +P +      Q  ++   ++ ++ L   S + +I      ++ I +  
Sbjct: 394 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 450

Query: 367 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 423
            L L  DV V  ++           F    HT  I   +L  PK++LD     +    +P
Sbjct: 451 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 510

Query: 424 FQASVEFVFS---SSPEKIKGS 442
              +VE +F    +S + + GS
Sbjct: 511 SDFAVEILFGEKMTSSDVVAGS 532


>gi|109689707 transmembrane phosphatase with tensin homology isoform
           alpha [Homo sapiens]
          Length = 551

 Score =  108 bits (269), Expect = 5e-23
 Identities = 86/322 (26%), Positives = 157/322 (48%), Gaps = 24/322 (7%)

Query: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
           +DLDLTYVTERI+A +FP+   +  +R  ++E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 235 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKH 294

Query: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
            + +V      + + P L ++    K +  W++ D +++V ++CKG   + G +V A++ 
Sbjct: 295 FHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLI 354

Query: 258 YSKISAGADQALATLTMRKFCEDKVATEL-----QPSQRRYISYFSGLLSGSIRMNSSP- 311
            S+I + A ++L     R+   DK  +E       PSQ+RY++YF+  +      N  P 
Sbjct: 355 ASEICSTAKESLYYFGERR--TDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 411

Query: 312 --LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEP 366
             LF+ + +I  +P +      Q  ++   ++ ++ L   S + +I      ++ I +  
Sbjct: 412 RILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNIT---TDKILIDVFD 468

Query: 367 ALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDER---FP 423
            L L  DV V  ++           F    HT  I   +L  PK++LD     +    +P
Sbjct: 469 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP 528

Query: 424 FQASVEFVFS---SSPEKIKGS 442
              +VE +F    +S + + GS
Sbjct: 529 SDFAVEILFGEKMTSSDVVAGS 550


>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
           isoform delta [Homo sapiens]
          Length = 411

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)

Query: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
           +DLDLTYVTERI+A +FP+   +  +R  + E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 106 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 165

Query: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
            + +V      + + P L ++    K +  W++ D +++V ++CKG KG+ G +V A + 
Sbjct: 166 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 225

Query: 258 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 311
            S+I   A+++L     R   K   +K      PSQ RY+ YF+  +      N  P   
Sbjct: 226 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 284

Query: 312 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 368
           LF+   +I  +         Q  ++   ++ S  L   S ++ I      ++ I++    
Sbjct: 285 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 341

Query: 369 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 423
            L  DV V  +            F   F+T  I   +L  P+++LD     +AW  + +P
Sbjct: 342 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 399

Query: 424 FQASVEFVF 432
            + +VE +F
Sbjct: 400 PEFAVEILF 408


>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
           isoform gamma [Homo sapiens]
          Length = 522

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)

Query: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
           +DLDLTYVTERI+A +FP+   +  +R  + E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 217 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 276

Query: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
            + +V      + + P L ++    K +  W++ D +++V ++CKG KG+ G +V A + 
Sbjct: 277 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 336

Query: 258 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 311
            S+I   A+++L     R   K   +K      PSQ RY+ YF+  +      N  P   
Sbjct: 337 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 395

Query: 312 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 368
           LF+   +I  +         Q  ++   ++ S  L   S ++ I      ++ I++    
Sbjct: 396 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 452

Query: 369 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 423
            L  DV V  +            F   F+T  I   +L  P+++LD     +AW  + +P
Sbjct: 453 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 510

Query: 424 FQASVEFVF 432
            + +VE +F
Sbjct: 511 PEFAVEILF 519


>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
           isoform alpha [Homo sapiens]
          Length = 445

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 84/309 (27%), Positives = 147/309 (47%), Gaps = 21/309 (6%)

Query: 139 WDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEKRHDLTR 197
           +DLDLTYVTERI+A +FP+   +  +R  + E+   L  KHR+ Y ++NL SE+ +D   
Sbjct: 140 FDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKH 199

Query: 198 LNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMH 257
            + +V      + + P L ++    K +  W++ D +++V ++CKG KG+ G +V A + 
Sbjct: 200 FHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLI 259

Query: 258 YSKISAGADQALATLTMR---KFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP--- 311
            S+I   A+++L     R   K   +K      PSQ RY+ YF+  +      N  P   
Sbjct: 260 ASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPRRI 318

Query: 312 LFLHYVLIPMLPAFEPGTGFQPFLK---IYQSMQLVYTSGVYHIAGPGPQQLCISLEPAL 368
           LF+   +I  +         Q  ++   ++ S  L   S ++ I      ++ I++    
Sbjct: 319 LFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIE---TDKILINVYDGP 375

Query: 369 LLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLD-----EAWTDERFP 423
            L  DV V  +            F   F+T  I   +L  P+++LD     +AW  + +P
Sbjct: 376 PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAW--KIYP 433

Query: 424 FQASVEFVF 432
            + +VE +F
Sbjct: 434 PEFAVEILF 442


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 109/387 (28%), Positives = 152/387 (39%), Gaps = 39/387 (10%)

Query: 789  GHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGY-PSP-GAHSPRAGSISPGSP 846
            G  G+         G  P Y PA+   P S GSPG    Y PSP GA SP   S SP SP
Sbjct: 1542 GAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSP---SYSPTSP 1598

Query: 847  PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLA-SAESLEPVSWREGPSGHSTLPRSPR 905
             Y          P   GG     P +  ++   + ++ S  P S    P+  S  P SP 
Sbjct: 1599 AYE---------PRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPS 1649

Query: 906  DAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTG 965
             +P S S     P++P ++ +      ++      SP+ +PT   S     P  S     
Sbjct: 1650 YSPTSPS---YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPS 1705

Query: 966  KAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSP--VPTTLPGLR 1023
             +P  PS S   P + SP SP++ P+SPS  P   S    S   SP SP   PT+     
Sbjct: 1706 YSPTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSP 1764

Query: 1024 HAPWQGPRGP---PDSPDGSPLTP--VPSQMPWLVASPEPPQSSP-----TPAF-PLAAS 1072
             +P   P  P   P SP+ SP +P   P+   +   SP    SSP     +P + P + S
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPS 1824

Query: 1073 YDTNGLSQPPLPEKRHLPGPGQQPG-----PWGPEQASSPARGISHHVTFAPLLSDNVPQ 1127
            Y  +  S  P   K     P   P      P  P+ + +  +       ++P      P 
Sbjct: 1825 YSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPT 1884

Query: 1128 TPE-PPTQESQSNVKFVQDTSKFWYKP 1153
            TP+  PT  + S    V   +   Y P
Sbjct: 1885 TPKYSPTSPTYSPTSPVYTPTSPKYSP 1911



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 110/404 (27%), Positives = 147/404 (36%), Gaps = 44/404 (10%)

Query: 760  PDYSCLKPPKAGEEGHEGCSYTMCPE-GRYGHPGY----PALVTYSYGGAVPSYCPAYGR 814
            P YS    P  G  G  G S    P  G    P Y    PA    S GG  P   P+Y  
Sbjct: 1559 PGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQ-SPSYSP 1617

Query: 815  VPHSCG------SPGEGRGYPSPGAHSPRAGSISPGSPPY-PQSRKLSYEIPTEEGGDRY 867
               S        SP      P+  ++SP + S SP SP Y P S   S   P+       
Sbjct: 1618 TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS----- 1672

Query: 868  PLPGHLASAGPLAS--AESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPS----TP 921
            P     +   P  S  + S  P S    P+  S  P SP  +P S S   + PS    +P
Sbjct: 1673 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1732

Query: 922  LHTSSPVQGKESTRRQDTRSPTSAPTQ-RLSP-GEALPPVSQAGTGKAPEL-PSGSGPEP 978
             ++ +      ++      SP   PT    SP   +  P S   T  +P   P+     P
Sbjct: 1733 SYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSP 1792

Query: 979  LAPS--PVSPTFPPSSPSDWPQERSPGGHSDGASPRSP--VPTTLPGLRHAPWQGPRGP- 1033
             +PS  P SP++ PSSP   PQ  +    S   SP SP   PT+      +P   P  P 
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPE 1852

Query: 1034 --PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAF-PLAASYDTNGLSQPPLPEKRHLP 1090
              P SP  SP +P  S      +   P  S  TP + P + +Y        P   K    
Sbjct: 1853 YTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPT 1912

Query: 1091 GPGQQP-----GPWGPEQASSPARGISHHVTFAPLLSDNVPQTP 1129
             P   P      P  P  + +  +G     T++P      P +P
Sbjct: 1913 SPTYSPTSPKYSPTSPTYSPTSPKG----STYSPTSPGYSPTSP 1952



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 92/327 (28%), Positives = 123/327 (37%), Gaps = 57/327 (17%)

Query: 853  KLSYEIPTEEGGDRYPLPGHLASAGP----LASAES----LEPVS--WREGPS------- 895
            K   EIPT        +PG L +AGP      SA S    + P    W +G +       
Sbjct: 1481 KYGMEIPTN-------IPG-LGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWS 1532

Query: 896  ---GHSTLPRSPRDAPCSASSELSGPSTPLHTS-SPVQGKESTRRQDTRSPTSAPTQRLS 951
               G    P +   +P SA+S+ SG S     + SP  G          SP  +     S
Sbjct: 1533 PSVGSGMTPGAAGFSP-SAASDASGFSPGYSPAWSPTPGSPG-------SPGPSSPYIPS 1584

Query: 952  PGEALPP-VSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGAS 1010
            PG A+ P  S       P  P G  P+  + SP SP++ P+SPS  P   +    S   S
Sbjct: 1585 PGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYS 1644

Query: 1011 PRSP--VPTTLPGLRHAPWQGPRGP---PDSPDGSPLTP-----VPSQMPWLVA-SPEPP 1059
            P SP   PT+      +P   P  P   P SP  SP +P      PS  P   + SP  P
Sbjct: 1645 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1704

Query: 1060 QSSPT-PAF-PLAASYDTNGLSQPPLPEKRHLPGPGQQP-----GPWGPEQASSPARGIS 1112
              SPT P++ P + SY     S  P         P   P      P  P    +      
Sbjct: 1705 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSP 1764

Query: 1113 HHVTFAPLLSDNVPQTPE-PPTQESQS 1138
               +++P   +  P +P   PT  S S
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYS 1791



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 112/465 (24%), Positives = 153/465 (32%), Gaps = 57/465 (12%)

Query: 557  GCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGH--RPGLSR-HCSCRQGYREPCG 613
            G G+  G  G     A   D    + G  P     PG    PG S  +     G   P  
Sbjct: 1536 GSGMTPGAAGFSPSAA--SDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSY 1593

Query: 614  VPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK--P 671
             P    Y P           GGY      Y+  S        S S     Y P      P
Sbjct: 1594 SPTSPAYEPRSP--------GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSP 1645

Query: 672  ATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEA 731
             +  +   +P Y        P  P+  P          PT+  Y       +    +   
Sbjct: 1646 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS----PTSPSYSPTSPSYSPTSPSYSP 1701

Query: 732  GKPLLHPVRPGHP--LPLLLPACGHHHAPMPDYSCLKP---PKAGEEGHEGCSYTMCPEG 786
              P   P  P +    P   P    +    P YS   P   P +        +YT  P  
Sbjct: 1702 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYT--PTS 1759

Query: 787  RYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSP 846
                P  P     SY    P+Y P          SP      P+  ++SP + S SP SP
Sbjct: 1760 PSYSPTSP-----SYSPTSPNYTPTSPNY-----SPTSPSYSPTSPSYSPTSPSYSPSSP 1809

Query: 847  PY-PQSRKLSYEIPT--EEGGDRYPLPGHLASAGPLASAESLE--PVSWREGPSGHSTLP 901
             Y PQS   +   P+         P         P  S  S E  P S +  P+     P
Sbjct: 1810 RYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSP 1869

Query: 902  RSPRDAPCSASSELS----GPSTPLHT-SSPVQGKESTRRQDTRSPTSAPTQRLSPGEAL 956
             SP+ +P S +   +     P++P ++ +SPV    S +   T SPT +PT         
Sbjct: 1870 TSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPT-SPTYSPTS-------- 1920

Query: 957  PPVSQAGTGKAPELPSGSGPEPLAP--SPVSPTFPPSSPSDWPQE 999
            P  S      +P  P GS   P +P  SP SPT+  +SP+  P +
Sbjct: 1921 PKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDD 1965



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 95/380 (25%), Positives = 134/380 (35%), Gaps = 36/380 (9%)

Query: 656  SLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALY 715
            ++S    P  P     + G +  ++P Y        P  P+  P          PT+  Y
Sbjct: 1588 AMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYS----PTSPSY 1643

Query: 716  GLRLEREAGEGWASEAGKPLLHPVRPGHP--LPLLLPACGHHHAPMPDYSCLKP---PKA 770
                   +    +     P   P  P +    P   P    +    P YS   P   P +
Sbjct: 1644 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1703

Query: 771  GEEGHEGCSYT-MCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYP 829
                    SY+   P      P Y    + SY    PSY P          SP      P
Sbjct: 1704 PSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPNY-----SPTSPNYTP 1757

Query: 830  SPGAHSPRAGSISPGSPPY-PQSRKLSYEIPTEE--GGDRYPLPGHLASAGPLASAES-- 884
            +  ++SP + S SP SP Y P S   S   P+         P     + + P  + +S  
Sbjct: 1758 TSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPT 1817

Query: 885  LEPVSWREGPSGHSTLPRSPRDAPCSASSELSGP----STPLHTSSPVQGKESTRRQDTR 940
              P S    PS  S  P SP+  P S S   S P    ++P ++ +  +   ++ +    
Sbjct: 1818 YTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPT 1877

Query: 941  SPTSAPTQ-RLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 999
            SPT +PT  + SP    P  S       P  P  S   P   SP SP + P+SP+  P  
Sbjct: 1878 SPTYSPTTPKYSPTS--PTYSPTSPVYTPTSPKYSPTSPTY-SPTSPKYSPTSPTYSP-- 1932

Query: 1000 RSPGGH-----SDGASPRSP 1014
             SP G      S G SP SP
Sbjct: 1933 TSPKGSTYSPTSPGYSPTSP 1952


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 174/674 (25%), Positives = 223/674 (33%), Gaps = 83/674 (12%)

Query: 485  RGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG----R 540
            R P   +P     RPP       SP PPPP   +     G +  +  +P AE  G     
Sbjct: 15   RTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 541  PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGG-GPHLGVYPGHRPGLS 599
              P +A R    R  G     S    A R  A    E  P      P     PG   G +
Sbjct: 69   TIPESAPRAGPTRSAG----TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124

Query: 600  RHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYE---GSPQGYAEASMEKRRLCRS 656
            R     Q              +     +R  L+ G      G   G    +M +R     
Sbjct: 125  RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184

Query: 657  LSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYG 716
               GL P P    +P     G R        +          P PA   +   P+A   G
Sbjct: 185  TEVGL-PRPAPSARPRPPTEGPRKS------VSSASEHSTTEPSPAARRR---PSA---G 231

Query: 717  LRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPD-YSCLKPPKAGEEGH 775
              L+R A    +S A  PL  P R G        A  H   P P     L+PP+      
Sbjct: 232  GGLQRPASRSLSSSA-TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290

Query: 776  EGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCP-AYGRVPHSCGSPGEGRGYPSPGAH 834
            +            G      L T S   A+ S  P      PHS     +    P P A 
Sbjct: 291  DAAP-------ALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ-LATPLPLAP 342

Query: 835  SPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 894
                   SP +PP  Q+       P  +       P   A+   L S   L P++    P
Sbjct: 343  P------SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLA-TPPP 394

Query: 895  SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKEST---RRQDTRSPTSAPTQRLS 951
                 L   P  AP S  +  S P +PL T SP           +     P S P Q   
Sbjct: 395  QAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452

Query: 952  PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP 1011
               A PPVS + T  +   PS + P PL   P  P  PP SPS  P  ++P   +  A P
Sbjct: 453  SPPASPPVSPSATPPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAPPPLA--APP 509

Query: 1012 ---RSPVPTTLPGLRHAPWQGPRGPPDS-PDGSPLTPVPSQMPWLVASPEPPQSSPTPAF 1067
                 P P   P L   P Q    PP S P  +P +P  S +P    +  PPQ+ P  A 
Sbjct: 510  LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLATPPPQAPPVLAA 568

Query: 1068 PLAASYDTNGLSQPPL-PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVP 1126
            PL        L  PP  P    L  P + P P GP+ + S  R          L     P
Sbjct: 569  PL--------LQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPR----------LTLALAP 609

Query: 1127 QTPEPPTQESQSNV 1140
              P PP++   S +
Sbjct: 610  GPPPPPSRSPSSTL 623



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 111/425 (26%), Positives = 155/425 (36%), Gaps = 51/425 (12%)

Query: 810  PAYGRVPHSCGSP-GEGRGYPSPGAHSPRAG---SISPGSP-----PYPQSRKLSYEIPT 860
            PA  R   + G+  G  R  PS     P  G   S+S  S      P P +R+     P+
Sbjct: 174  PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR----PS 229

Query: 861  EEGGDRYPLPGHLAS-AGPLASAESLEPVSWREGPSGHST--LPRSPRDAPCSASSELSG 917
              GG + P    L+S A PL+S         R GPS   T   P  P          L  
Sbjct: 230  AGGGLQRPASRSLSSSATPLSSPA-------RSGPSARGTPRAPAHPSQPKPKGLQALRP 282

Query: 918  PST--PLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVS-----QAGTGKAPEL 970
            P    P   ++P  G  S+    T SP++A   +  P     P S     Q  T      
Sbjct: 283  PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342

Query: 971  PSGSGPEPLAPSPVSPTFPPS-SPSDWPQERSPGGHSDGASP-----RSPVPTTLPGLRH 1024
            PS S P  L   P  P  PPS + +          HS   SP      +P P   P L  
Sbjct: 343  PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402

Query: 1025 APWQGPRGPPDSPDGSPL-TPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPL 1083
             P Q P  PP SP  SPL TP P     L         SP P+ P+ A +     + PP+
Sbjct: 403  PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPV 460

Query: 1084 PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFV 1143
                    P   P    P   ++P   +      +P +S +    P+ P   +   ++  
Sbjct: 461  -------SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513

Query: 1144 QDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGD 1203
            +   +    P L+     AL     P +F  +   S   +  ++  +ATPPP A P    
Sbjct: 514  KPPPQA--PPALATPPLQAL--PSPPASFPGQAPFSPSASLPMS-PLATPPPQAPPVLAA 568

Query: 1204 PVEQL 1208
            P+ Q+
Sbjct: 569  PLLQV 573



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 173/671 (25%), Positives = 221/671 (32%), Gaps = 122/671 (18%)

Query: 479  GSLTHTRGPLDGSPYAQVQRPPRQTP-------PAPSPEPPPP---PMLSVSSDSGHSST 528
            G+   T GP  G+P   + R  R          PAPS  P PP   P  SVSS S HS+T
Sbjct: 159  GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 529  LTTEPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQ--PTVGGGP 586
                        P P A  R       GG       R        L    +  P+  G P
Sbjct: 219  -----------EPSPAARRRPSA----GGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263

Query: 587  HLGVYPGH-RP-GLSRHCSCRQGYREPCGVPNGGYYRPE-GTLERRRLAYGGYEGSPQGY 643
                +P   +P GL       Q  R P   P      P  G L    LA      + Q  
Sbjct: 264  RAPAHPSQPKPKGL-------QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316

Query: 644  AEASMEKRRLCRSLSEGLY-PYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPA 702
            A  ++       SL+  L  P P     P+       AP   + +    P  PA  P  A
Sbjct: 317  APPTLPATPHSSSLTCQLATPLPLAPPSPS-------APPSLQTL----PSPPATPPSQA 365

Query: 703  CEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVR---PGHPLPLLLPACGHHHAP- 758
                L  PT             +   S    P L P+    P  P  L LP      +P 
Sbjct: 366  TTS-LGSPTL------------QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 759  -MPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAY---GR 814
              P  S L  P               P   +  P  P +       A P   P+     +
Sbjct: 413  ASPPLSPLATPSPQAPNALAVHLLQAP---FSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469

Query: 815  VPHSCGSPGEGRGYPSPGAHSPRAGSISPG--SPPYPQSRKLSYEIPTEEGGDRYPLPGH 872
             P S  +P   +  PSP A  P + S +P   +PP   +  L    P  +       P  
Sbjct: 470  APPSLAAPPL-QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 528

Query: 873  LASAGPLASAESLEPVSWREGPSGHSTLPRSP-RDAPCSASSELSGPSTPLHTSSPVQGK 931
             A   P AS     P S    PS  ++LP SP    P  A   L+ P   +  S P    
Sbjct: 529  QALPSPPASFPGQAPFS----PS--ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582

Query: 932  -ESTRRQDTRSP---TSAP--TQRLSPGEALPPV-SQAGTGKAPELPSGSGPEPLAPSPV 984
             ++ RR  T  P    S P  T  L+PG   PP  S + T   P+L   S          
Sbjct: 583  LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS---------- 632

Query: 985  SPTFPPSSPSDWPQERS--PGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL 1042
                  SS +  P+E      G   GA+   P    L     A W     PP +  G+P 
Sbjct: 633  ------SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686

Query: 1043 TPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNG-LSQPPLPEKRHLPGPGQQPGPWGP 1101
             P    +PW      PP + P  A  L   Y+T G  S  P P       PG  PG  G 
Sbjct: 687  AP----LPW------PPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGG 733

Query: 1102 EQASSPARGIS 1112
            + A+    G S
Sbjct: 734  KAAAGAGAGAS 744



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 128/501 (25%), Positives = 168/501 (33%), Gaps = 79/501 (15%)

Query: 849  PQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESL--EPVSWREGPSGHSTLPRSPRD 906
            P +R      P   G  R P P   A+   L +A ++  +P++ R G  G +T+P S   
Sbjct: 17   PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES--- 73

Query: 907  APCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP-----PVSQ 961
            AP +  +  +G S+    S P       R    ++ +  P    SPG A       P+ Q
Sbjct: 74   APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS--SPGRASGTTRPGPLGQ 131

Query: 962  AGT----------GKAPELPSGSGPEPLAPSPVS-PTFPPSSPSDWPQERSPGGHSDGAS 1010
             G           GKA E P  S     A    S PT  P +PS     RS    ++   
Sbjct: 132  KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGTEVGL 189

Query: 1011 PRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLT---PVPSQMPWLVASPEPP--QSSPTP 1065
            PR P P+  P     P +GPR    S      T   P   + P      + P  +S  + 
Sbjct: 190  PR-PAPSARP---RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245

Query: 1066 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1125
            A PL++       S P        P    QP P G  QA  P +        AP L    
Sbjct: 246  ATPLSSP----ARSGPSARGTPRAPAHPSQPKPKGL-QALRPPQVTPPRKDAAPALG--- 297

Query: 1126 PQTPEPPTQESQSNVKFVQDTSKFWYKPH---LSRDQAIAL-LKDKDPGAFLIRDSHSFQ 1181
            P +  P    S S     Q        PH   L+   A  L L    P A       S Q
Sbjct: 298  PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA-----PPSLQ 352

Query: 1182 GAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQ 1241
                L    ATPP  A    G P  Q    FL             PS P        +S 
Sbjct: 353  T---LPSPPATPPSQATTSLGSPTLQATHSFL-------------PSPP--------LSP 388

Query: 1242 HSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTG 1301
             +  P   P  L +P   PL+  P  P    +S  A    Q      ++L          
Sbjct: 389  LATPPPQAPPALALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445

Query: 1302 PQAVARAS-SAALSCSPRPTP 1321
            P   A  S  A+   SP  TP
Sbjct: 446  PPVQAPFSPPASPPVSPSATP 466



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 64/256 (25%), Positives = 81/256 (31%), Gaps = 29/256 (11%)

Query: 806  PSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAG-SISPGSPPYPQS-----RKLSYEIP 859
            P   P     P     P     +P     SP A   +SP + P PQ+       L    P
Sbjct: 516  PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575

Query: 860  TEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPC-SASSELSGP 918
            +         P    + GP  S           GP     L   P   P  S SS LSGP
Sbjct: 576  SPPASPTLQAPRRPPTPGPDTSVS---------GPRLTLALAPGPPPPPSRSPSSTLSGP 626

Query: 919  STPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEP 978
                H+SS     E  R  D+  P         P   L     A   + P  P      P
Sbjct: 627  DLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685

Query: 979  LAPSPVSPTFPPSS--------PSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP 1030
             AP P  P   P S         ++ P+  +P   + GA    P P T  G + A   G 
Sbjct: 686  GAPLPWPPATGPGSADGLCTIYETEGPESATP---APGALDPGPSPGTSGG-KAAAGAGA 741

Query: 1031 RGPPDSPDGSPLTPVP 1046
                 SP  + L  +P
Sbjct: 742  GASSRSPKQARLGELP 757



 Score = 31.2 bits (69), Expect = 7.4
 Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 6/129 (4%)

Query: 961  QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1020
            +A  G A   P+   P  L P P     PP  P   P      G + GA  R P+     
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLG-AAGAVGRKPLAERAG 63

Query: 1021 GLRHA--PWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL 1078
            G+  A  P   PR  P    G+      S+ P        P +  T   P+++    +G 
Sbjct: 64   GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123

Query: 1079 SQP-PLPEK 1086
            ++P PL +K
Sbjct: 124  TRPGPLGQK 132


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 95/346 (27%), Positives = 117/346 (33%), Gaps = 51/346 (14%)

Query: 726  GWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPE 785
            G  S + KP   P  PG      +P+ GH   P        PP   + G +       P+
Sbjct: 132  GGRSTSAKPFSPPSGPGR---FPVPSPGHRSGPPEPQRNRMPPPRPDVGSK-------PD 181

Query: 786  GRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGS 845
                          S    VPS        PH+ GSP      P PG   PR  S  P  
Sbjct: 182  --------------SIPPPVPSTPRPIQSSPHNRGSP------PVPGG--PRQPSPGPTP 219

Query: 846  PPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPR 905
            PP+P +R  +       GG     P  L+S+ P ++   L P   R         P    
Sbjct: 220  PPFPGNRGTALG-----GGSIRQSP--LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272

Query: 906  DAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTG 965
            + P S   E   P  P +   PV             P   P  R  PG    P S +G  
Sbjct: 273  NRP-SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR--PGPPPLPPSSSGND 329

Query: 966  KAPELP------SGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVP--- 1016
            + P LP      S S P   +P    P  PP S    P  R P G S    P  PV    
Sbjct: 330  ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG 389

Query: 1017 TTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1062
            +T   L   P    R   DSP   P  P+P   P   A P PP S+
Sbjct: 390  STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 105/409 (25%), Positives = 138/409 (33%), Gaps = 79/409 (19%)

Query: 816  PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLAS 875
            P   G+ G G G+   G      G    GS                 GG   P  G L  
Sbjct: 62   PKGAGAGGGGGGFGGGGGFGGGGGGGGGGS----------------FGGGGPPGLGGLFQ 105

Query: 876  AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKES-- 933
            AG       L   + R+  SG S  P  P     +++   S PS P     P  G  S  
Sbjct: 106  AG----MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP 161

Query: 934  TRRQDTRSPTSAPTQRLSPGEALPPVS------QAGTGKAPELPSGSGPEPLAPSPVSPT 987
               Q  R P   P     P    PPV       Q+        P   GP   +P P  P 
Sbjct: 162  PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221

Query: 988  FPPSSPS---DWPQERSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRG--------- 1032
            FP +  +        +SP   S   S R P+P T       +  P   P G         
Sbjct: 222  FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281

Query: 1033 -PPDSPDGS----PLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKR 1087
             PP  P  +    P TP PS        P PP     P  P ++S +      P LP++ 
Sbjct: 282  VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND---ETPRLPQRN 338

Query: 1088 --------HLPGPGQQPGPWGP---EQASSPAR---GISHHVTFAPLLSDN------VPQ 1127
                     LP PG+  GP  P   E+   P R   G S  +   P +S N      +P 
Sbjct: 339  LSLSSSTPPLPSPGRS-GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397

Query: 1128 TPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRD 1176
            TP+ P   S+S V    D+ +   +P L  D+  A      P +  IR+
Sbjct: 398  TPQLP---SRSGV----DSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 20/99 (20%)

Query: 475 DSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPM-----------------L 517
           DS+   +  T  P+  SP+ +   P    P  PSP P PPP                  L
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240

Query: 518 SVSSDSGHSSTLTTEPAA---ESPGRPPPTAAERQELDR 553
           S SS   +   L   P+    + P  PPP    R  + R
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 10/71 (14%)

Query: 487 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSD------SGHSSTLTTEPAAESPGR 540
           P    P A  Q PP   PP+  P PPP P  S  +D        + S  ++ P   SPGR
Sbjct: 295 PSTPRPSASSQAPPPPPPPS-RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353

Query: 541 P---PPTAAER 548
               PP  +ER
Sbjct: 354 SGPLPPPPSER 364



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%)

Query: 501 RQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP--PPTAAERQELDRL 554
           R+  P P P+   PP+ S    S  S      P    PG P  PP+++   E  RL
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 11/71 (15%)

Query: 486 GPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEP------AAESP- 538
           GPL   P  +   P R  P    P PPPPP   VS +   S  L   P        +SP 
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPP---VSRNGSTSRALPATPQLPSRSGVDSPR 411

Query: 539 -GRPPPTAAER 548
            G  PP   +R
Sbjct: 412 SGPRPPLPPDR 422


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 95/346 (27%), Positives = 117/346 (33%), Gaps = 51/346 (14%)

Query: 726  GWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPE 785
            G  S + KP   P  PG      +P+ GH   P        PP   + G +       P+
Sbjct: 132  GGRSTSAKPFSPPSGPGR---FPVPSPGHRSGPPEPQRNRMPPPRPDVGSK-------PD 181

Query: 786  GRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGS 845
                          S    VPS        PH+ GSP      P PG   PR  S  P  
Sbjct: 182  --------------SIPPPVPSTPRPIQSSPHNRGSP------PVPGG--PRQPSPGPTP 219

Query: 846  PPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPR 905
            PP+P +R  +       GG     P  L+S+ P ++   L P   R         P    
Sbjct: 220  PPFPGNRGTALG-----GGSIRQSP--LSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272

Query: 906  DAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTG 965
            + P S   E   P  P +   PV             P   P  R  PG    P S +G  
Sbjct: 273  NRP-SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR--PGPPPLPPSSSGND 329

Query: 966  KAPELP------SGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVP--- 1016
            + P LP      S S P   +P    P  PP S    P  R P G S    P  PV    
Sbjct: 330  ETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNG 389

Query: 1017 TTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1062
            +T   L   P    R   DSP   P  P+P   P   A P PP S+
Sbjct: 390  STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 105/409 (25%), Positives = 138/409 (33%), Gaps = 79/409 (19%)

Query: 816  PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLAS 875
            P   G+ G G G+   G      G    GS                 GG   P  G L  
Sbjct: 62   PKGAGAGGGGGGFGGGGGFGGGGGGGGGGS----------------FGGGGPPGLGGLFQ 105

Query: 876  AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKES-- 933
            AG       L   + R+  SG S  P  P     +++   S PS P     P  G  S  
Sbjct: 106  AG----MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP 161

Query: 934  TRRQDTRSPTSAPTQRLSPGEALPPVS------QAGTGKAPELPSGSGPEPLAPSPVSPT 987
               Q  R P   P     P    PPV       Q+        P   GP   +P P  P 
Sbjct: 162  PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221

Query: 988  FPPSSPS---DWPQERSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRG--------- 1032
            FP +  +        +SP   S   S R P+P T       +  P   P G         
Sbjct: 222  FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281

Query: 1033 -PPDSPDGS----PLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKR 1087
             PP  P  +    P TP PS        P PP     P  P ++S +      P LP++ 
Sbjct: 282  VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND---ETPRLPQRN 338

Query: 1088 --------HLPGPGQQPGPWGP---EQASSPAR---GISHHVTFAPLLSDN------VPQ 1127
                     LP PG+  GP  P   E+   P R   G S  +   P +S N      +P 
Sbjct: 339  LSLSSSTPPLPSPGRS-GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397

Query: 1128 TPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRD 1176
            TP+ P   S+S V    D+ +   +P L  D+  A      P +  IR+
Sbjct: 398  TPQLP---SRSGV----DSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 20/99 (20%)

Query: 475 DSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPM-----------------L 517
           DS+   +  T  P+  SP+ +   P    P  PSP P PPP                  L
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240

Query: 518 SVSSDSGHSSTLTTEPAA---ESPGRPPPTAAERQELDR 553
           S SS   +   L   P+    + P  PPP    R  + R
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR 279



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 10/71 (14%)

Query: 487 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSD------SGHSSTLTTEPAAESPGR 540
           P    P A  Q PP   PP+  P PPP P  S  +D        + S  ++ P   SPGR
Sbjct: 295 PSTPRPSASSQAPPPPPPPS-RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353

Query: 541 P---PPTAAER 548
               PP  +ER
Sbjct: 354 SGPLPPPPSER 364



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%)

Query: 501 RQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP--PPTAAERQELDRL 554
           R+  P P P+   PP+ S    S  S      P    PG P  PP+++   E  RL
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 11/71 (15%)

Query: 486 GPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEP------AAESP- 538
           GPL   P  +   P R  P    P PPPPP   VS +   S  L   P        +SP 
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPP---VSRNGSTSRALPATPQLPSRSGVDSPR 411

Query: 539 -GRPPPTAAER 548
            G  PP   +R
Sbjct: 412 SGPRPPLPPDR 422


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 167/672 (24%), Positives = 217/672 (32%), Gaps = 118/672 (17%)

Query: 485  RGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG----R 540
            R P   +P     RPP       SP PPPP   +     G +  +  +P AE  G     
Sbjct: 15   RTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 541  PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSR 600
              P +A R    R        + GRG         +   P     P     PG   G +R
Sbjct: 69   TIPESAPRAGPTRT---SRPPASGRG---------ERAPPAKNTSPGPVSSPGRASGTTR 116

Query: 601  HCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYE---GSPQGYAEASMEKRRLCRSL 657
                 Q              +     +R  L+ G      G   G    +M +R      
Sbjct: 117  PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176

Query: 658  SEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGL 717
              GL P P    +P     G R        +          P PA   +   P+A   G 
Sbjct: 177  EVGL-PRPAPSARPRPPTEGPRKS------VSSASEHSTTEPSPAARRR---PSA---GG 223

Query: 718  RLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPD-YSCLKPPKAGEEGHE 776
             L+R A    +S A  PL  P R G        A  H   P P     L+PP+       
Sbjct: 224  GLQRPASRSLSSSA-TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ------- 275

Query: 777  GCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSP 836
                 + P  +   P    L +       PS        P S  +P   +  PSP A  P
Sbjct: 276  -----VTPPRKDAAPALGPLSSSPLATPSPS-------APPSPSAPPSLQTLPSPPATPP 323

Query: 837  RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSG 896
               + S GSP    +       P                  PLA+            P  
Sbjct: 324  SQATTSLGSPTLQATHSFLPSPPLS----------------PLATPP----------PQA 357

Query: 897  HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKEST---RRQDTRSPTSAPTQRLSPG 953
               L   P  AP S  +  S P +PL T SP           +     P S P Q     
Sbjct: 358  PPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 954  EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP-- 1011
             A PPVS + T  +   PS + P PL   P  P  PP SPS  P  ++P   +  A P  
Sbjct: 416  PASPPVSPSATPPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAPPPLA--APPLQ 472

Query: 1012 -RSPVPTTLPGLRHAPWQGPRGPPDS-PDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPL 1069
               P P   P L   P Q    PP S P  +P +P  S +P    +  PPQ+ P  A PL
Sbjct: 473  LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLATPPPQAPPVLAAPL 531

Query: 1070 AASYDTNGLSQPPL-PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQT 1128
                    L  PP  P    L  P + P P GP+ + S  R          L     P  
Sbjct: 532  --------LQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPR----------LTLALAPGP 572

Query: 1129 PEPPTQESQSNV 1140
            P PP++   S +
Sbjct: 573  PPPPSRSPSSTL 584



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 116/458 (25%), Positives = 158/458 (34%), Gaps = 78/458 (17%)

Query: 810  PAYGRVPHSCGSPGEGRGYPSPG--------------------AHSPRAGSISPG----- 844
            PA    P    SPG   G   PG                      +P+  ++S G     
Sbjct: 96   PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 155

Query: 845  SPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSP 904
            S P P +   +    +   G    LP    SA P    E   P       S HST   SP
Sbjct: 156  SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG--PRKSVSSASEHSTTEPSP 213

Query: 905  --RDAPCS-------ASSELSGPSTPLHTSSPVQGKESTRRQDTR-----SPTSAPTQRL 950
              R  P +       AS  LS  +TPL  SSP +   S R           P     Q L
Sbjct: 214  AARRRPSAGGGLQRPASRSLSSSATPL--SSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271

Query: 951  SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPS-----SPSDWPQERSPGG- 1004
             P +  PP   A     P L S     P   +P SP+ PPS     SP   P  ++    
Sbjct: 272  RPPQVTPPRKDAAPALGP-LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330

Query: 1005 --------HSDGASP-----RSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL-TPVPSQMP 1050
                    HS   SP      +P P   P L   P Q P  PP SP  SPL TP P    
Sbjct: 331  GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390

Query: 1051 WLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARG 1110
             L         SP P+ P+ A +     + PP+        P   P    P   ++P   
Sbjct: 391  ALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPV-------SPSATPPSQAPPSLAAPPLQ 441

Query: 1111 ISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPG 1170
            +      +P +S +    P+ P   +   ++  +   +    P L+     AL     P 
Sbjct: 442  VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA--PPALATPPLQAL--PSPPA 497

Query: 1171 AFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQL 1208
            +F  +   S   +  ++  +ATPPP A P    P+ Q+
Sbjct: 498  SFPGQAPFSPSASLPMS-PLATPPPQAPPVLAAPLLQV 534



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 168/663 (25%), Positives = 213/663 (32%), Gaps = 136/663 (20%)

Query: 479  GSLTHTRGPLDGSPYAQVQRPPRQTP-------PAPSPEPPPP---PMLSVSSDSGHSST 528
            G+   T GP  G+P   + R  R          PAPS  P PP   P  SVSS S HS  
Sbjct: 150  GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-- 207

Query: 529  LTTEPAAESPGRPPPTAAERQELDRLLGGCG--VASGGRGAGRETAILDDEEQPTVGGGP 586
             TTEP+  +  RP      ++   R L      ++S  R              P+  G P
Sbjct: 208  -TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG------------PSARGTP 254

Query: 587  HLGVYPGH-RP-GLSRHCSCRQGYREPCGVPNGGYYRPE-GTLERRRLAYGGYEGSPQGY 643
                +P   +P GL       Q  R P   P      P  G L    LA       P   
Sbjct: 255  RAPAHPSQPKPKGL-------QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307

Query: 644  AEASMEKRRLCRSLSEGLYPYPPEMG-KPATGDFGYRAPGYREVVILEDPGLPALYPCPA 702
            A  S++             P PP      AT   G          +   P  P   P P 
Sbjct: 308  APPSLQT-----------LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356

Query: 703  CEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDY 762
                LALP              +   S    P L P+    P P    A   H    P  
Sbjct: 357  APPALALPPL------------QAPPSPPASPPLSPLAT--PSPQAPNALAVHLLQAPFS 402

Query: 763  SCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSP 822
                PP                +  +  P  P +         PS  P     P     P
Sbjct: 403  PPPSPPV---------------QAPFSPPASPPVS--------PSATPPSQAPPSLAAPP 439

Query: 823  GEGRGYPSPGAHSPRAGSISPG--SPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLA 880
             +    PSP A  P + S +P   +PP   +  L    P  +       P   A   P A
Sbjct: 440  LQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497

Query: 881  SAESLEPVSWREGPSGHSTLPRSP-RDAPCSASSELSGPSTPLHTSSPVQGK-ESTRRQD 938
            S     P S    PS  ++LP SP    P  A   L+ P   +  S P     ++ RR  
Sbjct: 498  SFPGQAPFS----PS--ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551

Query: 939  TRSP---TSAP--TQRLSPGEALPPV-SQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSS 992
            T  P    S P  T  L+PG   PP  S + T   P+L   S                SS
Sbjct: 552  TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS----------------SS 595

Query: 993  PSDWPQERS--PGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMP 1050
             +  P+E      G   GA+   P    L     A W     PP +  G+P  P    +P
Sbjct: 596  ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP----LP 651

Query: 1051 WLVASPEPPQSSPTPAFPLAASYDTNG-LSQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1109
            W      PP + P  A  L   Y+T G  S  P P       PG  PG  G + A+    
Sbjct: 652  W------PPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGGKAAAGAGA 702

Query: 1110 GIS 1112
            G S
Sbjct: 703  GAS 705



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 64/256 (25%), Positives = 81/256 (31%), Gaps = 29/256 (11%)

Query: 806  PSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAG-SISPGSPPYPQS-----RKLSYEIP 859
            P   P     P     P     +P     SP A   +SP + P PQ+       L    P
Sbjct: 477  PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 536

Query: 860  TEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPC-SASSELSGP 918
            +         P    + GP  S           GP     L   P   P  S SS LSGP
Sbjct: 537  SPPASPTLQAPRRPPTPGPDTSVS---------GPRLTLALAPGPPPPPSRSPSSTLSGP 587

Query: 919  STPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEP 978
                H+SS     E  R  D+  P         P   L     A   + P  P      P
Sbjct: 588  DLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 646

Query: 979  LAPSPVSPTFPPSS--------PSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP 1030
             AP P  P   P S         ++ P+  +P   + GA    P P T  G + A   G 
Sbjct: 647  GAPLPWPPATGPGSADGLCTIYETEGPESATP---APGALDPGPSPGTSGG-KAAAGAGA 702

Query: 1031 RGPPDSPDGSPLTPVP 1046
                 SP  + L  +P
Sbjct: 703  GASSRSPKQARLGELP 718



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 88/385 (22%), Positives = 130/385 (33%), Gaps = 45/385 (11%)

Query: 961  QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1020
            +A  G A   P+   P  L P P     PP  P   P      G + GA  R P+     
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLG-AAGAVGRKPLAERAG 63

Query: 1021 GL------RHAPWQGP---RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLA- 1070
            G+        AP  GP     PP S  G    P  +  P  V+SP     +  P  PL  
Sbjct: 64   GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQ 122

Query: 1071 -----ASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQAS-SPARGISHHV--TFAPLLS 1122
                 ++ +T    +     KR     G +    GP   + SPA         T   L  
Sbjct: 123  KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182

Query: 1123 DNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQG 1182
                  P PPT+  + +V    +        H + + + A  +    G  L R +   + 
Sbjct: 183  PAPSARPRPPTEGPRKSVSSASE--------HSTTEPSPAARRRPSAGGGLQRPAS--RS 232

Query: 1183 AYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCP--------SEPYFGS 1234
                A  +++P  S    +G P  +   H   +  PKG++    P        + P  G 
Sbjct: 233  LSSSATPLSSPARSGPSARGTP--RAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGP 289

Query: 1235 LSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSV 1294
            LS+     + SP + P     PS   L   P  P P+  +T+       A  S L    +
Sbjct: 290  LSS-SPLATPSPSAPPSPSAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPL 347

Query: 1295 ETESLTGPQAVARASSAALSCSPRP 1319
               +   PQA    +   L   P P
Sbjct: 348  SPLATPPPQAPPALALPPLQAPPSP 372


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 130/474 (27%), Positives = 169/474 (35%), Gaps = 72/474 (15%)

Query: 689  LEDPGLPALYP--CPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLP 746
            L  P  PA  P   P  +  L+LP +      L         S A  PL  P+   HPL 
Sbjct: 441  LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL---------SPAVSPLSSPLTI-HPLQ 490

Query: 747  LLLPACGHHHA---------PMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALV 797
             L     H            P+   S L PP          S T  P         P L 
Sbjct: 491  ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP---ASLTTPPLENLPSLAPPPLQ 547

Query: 798  TYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYE 857
            T S     P   P     P  C +P   +  PSP    P     S  +PP PQ+      
Sbjct: 548  TAS----APLTTPHLETPP--CPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALAS 600

Query: 858  IPTEEGGDRYPLPGHLASAGPLASAE-SLEPVSWREGPSGHSTLPRSPRDAPCSASSE-- 914
             P +  G   P    LA+  P A    +L P+  +  PS  ++ P SP   P   +    
Sbjct: 601  PPLQ--GLPSPPLSPLATPPPQAPPXLALPPL--QAPPSPPASPPLSPLATPSPQAPNAL 656

Query: 915  ----LSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKA-PE 969
                L  P +P   S PVQ   S       SP++ P  +  P  A PP+    +  A P 
Sbjct: 657  AVHLLQAPFSP-PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715

Query: 970  LPSGSGPEPLAPSPVSPT---FPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAP 1026
            +   + P P AP P++      PPS P+  P   S           +P P   P L   P
Sbjct: 716  MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA----------TPPPRVPPLLAAPP 765

Query: 1027 WQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP--AFPLAASYDTNGLSQPPLP 1084
             Q P  PP S   SPL   P Q P  +A+P P Q+ P+P  +FP           Q P  
Sbjct: 766  LQVPPSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPPASFP----------GQAPFS 814

Query: 1085 EKRHLP-GPGQQPGPWGPEQASSPARGISHHVTFAPLL-SDNVPQTPEPPTQES 1136
                LP  P   P P  P   ++P   +      +P L +   P TP P T  S
Sbjct: 815  PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 111/389 (28%), Positives = 145/389 (37%), Gaps = 50/389 (12%)

Query: 830  SPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVS 889
            S  +HSP+A   S   PP      L+              P    +  PL +  SL P  
Sbjct: 494  SLASHSPQAPLSSLIMPPLETQSSLA--------PPSLQTPPASLTTPPLENLPSLAPPP 545

Query: 890  WREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQR 949
             +   S   T P      PC A   L  P +PL T  P      T       P  AP   
Sbjct: 546  LQTA-SAPLTTPHL-ETPPCPAPCPLQAPPSPLTTPPP-----ETPSSIATPPPQAPPAL 598

Query: 950  LSP---GEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 1006
             SP   G   PP+S   T   P+ P      PL   P  P  PP SP   P  ++P   +
Sbjct: 599  ASPPLQGLPSPPLSPLAT-PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 1007 DGA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPT 1064
                 +P SP P+        P Q P  PP SP  SP    PSQ P  +A+P P Q  P+
Sbjct: 658  VHLLQAPFSPPPSP-------PVQAPFSPPASPPVSPSATPPSQAPPSLAAP-PLQVPPS 709

Query: 1065 PAF--PLAASYDTNGLSQPPL--PEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPL 1120
            P    P++ S      + PPL  P  +  P P   P P  P  A+ P R         PL
Sbjct: 710  PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-PMSPS-ATPPPR-------VPPL 760

Query: 1121 LSDNVPQTP-EPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHS 1179
            L+    Q P  PP     S +      +     P L+     AL     P +F  +   S
Sbjct: 761  LAAPPLQVPPSPPASLPMSPLAKPPPQAP----PALATPPLQAL--PSPPASFPGQAPFS 814

Query: 1180 FQGAYGLALKVATPPPSAQPWKGDPVEQL 1208
               +  ++  +ATPPP A P    P+ Q+
Sbjct: 815  PSASLPMS-PLATPPPQAPPVLAAPLLQV 842



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 124/497 (24%), Positives = 158/497 (31%), Gaps = 120/497 (24%)

Query: 840  SISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHST 899
            S SP + P P   K     P +      PLP  L  + PLA+   L P S    P    T
Sbjct: 300  SSSPLATPSPSGTKARPVPPPDNAAT--PLPATLPPSPPLATPLPLAPPS-PSAPPSLQT 356

Query: 900  LPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPV 959
            LP  P   P  A         P  T+ P+Q   S +   T  P   P    SP    PP 
Sbjct: 357  LPSPPATPPSQAP--------PSMTTPPMQAPPSLQ---TIPPIQVPHSLTSPSLQAPPS 405

Query: 960  SQAGTGKAPELPSGS------------GPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 1007
              A +        GS             P     S  SP+ P S+P D            
Sbjct: 406  PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD------------ 453

Query: 1008 GASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS--PEPPQSSPTP 1065
              SP    P +LP     P Q    P  SP  SPLT  P Q    +AS  P+ P SS   
Sbjct: 454  --SPPLQAPLSLPA--SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS--- 506

Query: 1066 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1125
                        L  PPL  +  L  P  Q  P                +T  PL  +N+
Sbjct: 507  ------------LIMPPLETQSSLAPPSLQTPPAS--------------LTTPPL--ENL 538

Query: 1126 PQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYG 1185
            P    PP Q + + +            PHL      A    + P + L         +  
Sbjct: 539  PSLAPPPLQTASAPLT----------TPHLETPPCPAPCPLQAPPSPLTTPPPETPSS-- 586

Query: 1186 LALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSIS 1245
                +ATPPP A P    P                  ++G PS P        +S  +  
Sbjct: 587  ----IATPPPQAPPALASP-----------------PLQGLPSPP--------LSPLATP 617

Query: 1246 PISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1305
            P   P  L +P   PL+  P  P    +S  A    Q      ++L          P   
Sbjct: 618  PPQAPPXLALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 1306 ARAS-SAALSCSPRPTP 1321
            A  S  A+   SP  TP
Sbjct: 675  APFSPPASPPVSPSATP 691



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 81/286 (28%), Positives = 105/286 (36%), Gaps = 22/286 (7%)

Query: 810  PAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPG-------SPPYPQSRKLSYEIPTEE 862
            PA    P    SPG   G   PG    +   IS         +   P+   LS     + 
Sbjct: 105  PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164

Query: 863  GGDRYPLPGHLASAGPLAS-AESLEPVSWREGPSGHSTLP-RSPRDAPCSASSELSGPST 920
             G   P PG  + A    S A   E    R  PS     P   PR +  SAS   +   +
Sbjct: 165  SG---PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221

Query: 921  PLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGP---E 977
            P     P  G    +R  +RS +S+ T   SP  + P  S  GT +AP  PS   P   +
Sbjct: 222  PAARRRPSAGG-GLQRPASRSLSSSATPLSSPARSGP--SARGTPRAPAHPSQPKPKGLQ 278

Query: 978  PLAPSPVSPTFPPSSPSDWPQERSP-GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDS 1036
             L P  V+P    ++P+  P   SP    S   +   PVP         P   P  PP +
Sbjct: 279  ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338

Query: 1037 PDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPP 1082
                   P PS  P L   P PP + P+ A P   S  T  +  PP
Sbjct: 339  TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP---SMTTPPMQAPP 381



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 81/299 (27%), Positives = 101/299 (33%), Gaps = 39/299 (13%)

Query: 829  PSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPV 888
            PSP A  P    +SP + P P+   L    P +      P P       PLA      P 
Sbjct: 739  PSPPASPP----MSPSATPPPRVPPLLAAPPLQVP----PSPPASLPMSPLAKPPPQAPP 790

Query: 889  SWREGPSGHSTLPRS--PRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAP 946
            +    P      P +  P  AP S S+ L  P +PL T  P Q          + P S P
Sbjct: 791  ALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPP-QAPPVLAAPLLQVPPSPP 847

Query: 947  TQRLSPGEALPPVSQAGTG-KAPELPSGSGPEPLAPSPVSPTFPPSSP---------SDW 996
                      PP     T    P L     P P  P   SP+   S P         +  
Sbjct: 848  ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907

Query: 997  PQERS--PGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVA 1054
            P+E      G   GA+   P    L     A W     PP +  G+P  P    +PW   
Sbjct: 908  PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP----LPW--- 960

Query: 1055 SPEPPQSSPTPAFPLAASYDTNG-LSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGIS 1112
               PP + P  A  L   Y+T G  S  P P       PG  PG  G + A+    G S
Sbjct: 961  ---PPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGGKAAAGAGAGAS 1013



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 120/506 (23%), Positives = 170/506 (33%), Gaps = 115/506 (22%)

Query: 849  PQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESL--EPVSWREGPSGHSTLPRSPRD 906
            P +R      P   G  R P P   A+   L +A ++  +P++ R G  G +T+P S   
Sbjct: 17   PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES--- 73

Query: 907  APCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP-----PVSQ 961
            AP +  +  +G S+    S P       R    ++ +  P    SPG A       P+ Q
Sbjct: 74   APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS--SPGRASGTTRPGPLGQ 131

Query: 962  AGT----------GKAPELP------SGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGH 1005
             G           GKA E P      +G+  +   P+P +P                   
Sbjct: 132  KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP------------------- 172

Query: 1006 SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP 1065
            S   + RS    T  GL       PR            P PS      A P PP   P  
Sbjct: 173  SPAMARRSRAAGTEVGL-------PR------------PAPS------ARPRPPTEGPRK 207

Query: 1066 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1125
            +   A+ + T      P P  R  P  G           SS A  +S      P    + 
Sbjct: 208  SVSSASEHSTT----EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP----SA 259

Query: 1126 PQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYG 1185
              TP  P   SQ   K +Q          L   Q     KD  P    +  S        
Sbjct: 260  RGTPRAPAHPSQPKPKGLQ---------ALRPPQVTPPRKDAAPALGPLSSS-------- 302

Query: 1186 LALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIK-----GCPSEPYFGSLSALVS 1240
                +ATP PS    +  P        L  T P    +        PS     SL  L S
Sbjct: 303  ---PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359

Query: 1241 QHSISPISLPCCLRIP---SKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVE-T 1296
              +  P   P  +  P   +   L+  P   VP ++++ +      A  S L L+S++ T
Sbjct: 360  PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS----LQAPPSPLALSSLQAT 415

Query: 1297 ESLTGPQAVARASSAALSCSPRPTPA 1322
             SL  P    +A+ + L+ SPR T A
Sbjct: 416  TSLGSP--TLQATHSFLTMSPRQTQA 439



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 68/271 (25%), Positives = 86/271 (31%), Gaps = 29/271 (10%)

Query: 791  PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAG-SISPGSPPYP 849
            P  PA +  S     P   P     P     P     +P     SP A   +SP + P P
Sbjct: 770  PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 850  QS-----RKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSP 904
            Q+       L    P+         P    + GP  S           GP     L   P
Sbjct: 830  QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS---------GPRLTLALAPGP 880

Query: 905  RDAPC-SASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAG 963
               P  S SS LSGP    H+SS     E  R  D+  P         P   L     A 
Sbjct: 881  PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAA 939

Query: 964  TGKAPELPSGSGPEPLAPSPVSPTFPPSS--------PSDWPQERSPGGHSDGASPRSPV 1015
              + P  P      P AP P  P   P S         ++ P+  +P   + GA    P 
Sbjct: 940  WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP---APGALDPGPS 996

Query: 1016 PTTLPGLRHAPWQGPRGPPDSPDGSPLTPVP 1046
            P T  G + A   G      SP  + L  +P
Sbjct: 997  PGTSGG-KAAAGAGAGASSRSPKQARLGELP 1026



 Score = 38.5 bits (88), Expect = 0.046
 Identities = 29/73 (39%), Positives = 34/73 (46%), Gaps = 13/73 (17%)

Query: 479 GSLTHTRGPLDGSPYAQVQRPPRQTP-------PAPSPEPPPP---PMLSVSSDSGHSST 528
           G+   T GP  G+P   + R  R          PAPS  P PP   P  SVSS S HS  
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-- 216

Query: 529 LTTEPAAESPGRP 541
            TTEP+  +  RP
Sbjct: 217 -TTEPSPAARRRP 228



 Score = 35.0 bits (79), Expect = 0.51
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 487 PLDGSPYAQVQRPPRQTPPAPSPEPPP--PPMLS---VSSDSGHSSTLTTEPAAESPGRP 541
           PL   P      PP   P +PS  PPP  PP+L+   +       ++L   P A+ P + 
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788

Query: 542 PPTAA 546
           PP  A
Sbjct: 789 PPALA 793



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 32/95 (33%), Positives = 38/95 (40%), Gaps = 19/95 (20%)

Query: 491 SPYAQV-QRPPRQTPP----------APSPEPPPPPMLSVSSD------SGHSSTLTTEP 533
           SP  Q  +RPP   P           A +P PPPPP  S SS       +GHSS+ T+ P
Sbjct: 849 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908

Query: 534 --AAESPGRPPPTAAERQELDRLLGGCGVASGGRG 566
                    P   AA     D  L  C  A+  RG
Sbjct: 909 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 16/48 (33%), Positives = 23/48 (47%)

Query: 499 PPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAA 546
           PP Q PP+P   PP  P+ + S  + ++  +    A  SP   PP  A
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 5/60 (8%)

Query: 492 PYAQVQRPPRQTPPAPSPEP-----PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAA 546
           P + + +PP Q PPA +  P      PP      +    S++L   P A  P + PP  A
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 2/56 (3%)

Query: 491 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAA 546
           SP A     P  TPP  +P P   P L V      S  ++  P+A  P R PP  A
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS--PSATPPPRVPPLLA 762



 Score = 31.2 bits (69), Expect = 7.4
 Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 6/129 (4%)

Query: 961  QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP 1020
            +A  G A   P+   P  L P P     PP  P   P      G + GA  R P+     
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLG-AAGAVGRKPLAERAG 63

Query: 1021 GLRHA--PWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL 1078
            G+  A  P   PR  P    G+      S+ P        P +  T   P+++    +G 
Sbjct: 64   GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123

Query: 1079 SQP-PLPEK 1086
            ++P PL +K
Sbjct: 124  TRPGPLGQK 132


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 148/620 (23%), Positives = 206/620 (33%), Gaps = 119/620 (19%)

Query: 738  PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT--------------MC 783
            P RP HP PL  P+      P P  S  + P+A  E H   + T                
Sbjct: 155  PARPYHPPPLFPPS------PQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA 208

Query: 784  PEGRYGHPGYPALVTYSYGGAV--PSYCPAYGRVPHSCGSPGEGRGYPSP---------- 831
            P G    P +P L     GG +  P   P  G    S G P  G+ +P P          
Sbjct: 209  PPG--APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266

Query: 832  ---------------GAHSPRAGS------ISPGSPPYPQSRKLSYEIPTEEGGDRYPLP 870
                           G + P A        ++P  PP P  R L+    +  G    PLP
Sbjct: 267  ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326

Query: 871  GHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQG 930
            GHL S   +       P    +GP    TL  SP   P ++SS  + P    ++SS    
Sbjct: 327  GHLPSPHAMGQGMGGLPPGPEKGP----TLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382

Query: 931  KESTRRQDTRSPTSAP---TQRLS--PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVS 985
              ++    + S +++P   +Q L   P    PP S + + + P+    S P     S   
Sbjct: 383  AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP 442

Query: 986  PTFPPSSPSDWPQERSPGGH--SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLT 1043
            P  PP           PG    S GA   +  P +     H   Q  +            
Sbjct: 443  PPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ--- 499

Query: 1044 PVPSQMPWLVASPEPPQSSPTP--------AFPLAASYDTNGLSQPPLPEKRHLPGPG-- 1093
                Q     + P PP + P P        A P A S     L +P  P   HLP P   
Sbjct: 500  ---QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL-RPYPPGPAHLPPPHSQ 555

Query: 1094 ---QQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPE------PP------TQESQS 1138
                Q GP GP  +SS     S      P    +  Q P+      PP      +  + S
Sbjct: 556  VSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615

Query: 1139 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPP---- 1194
             V     +S   YK            +   PGA+       ++     + +  TPP    
Sbjct: 616  TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG 675

Query: 1195 --PSAQPWKGDPVEQLVRHF-LIETGPKGV-KIKGCPSEPYFGSLSALVSQHSISPISLP 1250
              P A P    P    V    L   GP G+  +   P+ P  G            P+S  
Sbjct: 676  TSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASG-----------PPLSAT 724

Query: 1251 CCLRIPSKDPLEETPEAPVP 1270
               + P+++   ETPE+PVP
Sbjct: 725  QIKQEPAEE--YETPESPVP 742



 Score = 31.2 bits (69), Expect = 7.4
 Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 12/124 (9%)

Query: 433 SSSPEKIKGSTP-------RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTR 485
           +SSP   K ++P       +  PS       T P  +  S  +F         G+ +   
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT-SPPA 680

Query: 486 GPLDGSPYAQVQRPPRQTPPAPS--PEPPPPPMLSVSSDSGHSSTLTTEPAA--ESPGRP 541
           GP    P +    P    P  PS  P  PPPP    S     ++ +  EPA   E+P  P
Sbjct: 681 GPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESP 740

Query: 542 PPTA 545
            P A
Sbjct: 741 VPPA 744



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 15/48 (31%), Positives = 22/48 (45%)

Query: 500 PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAE 547
           P   PPA S  P PP     SS S  S+  ++  ++ S    P  A++
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 148/620 (23%), Positives = 206/620 (33%), Gaps = 119/620 (19%)

Query: 738  PVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT--------------MC 783
            P RP HP PL  P+      P P  S  + P+A  E H   + T                
Sbjct: 155  PARPYHPPPLFPPS------PQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA 208

Query: 784  PEGRYGHPGYPALVTYSYGGAV--PSYCPAYGRVPHSCGSPGEGRGYPSP---------- 831
            P G    P +P L     GG +  P   P  G    S G P  G+ +P P          
Sbjct: 209  PPG--APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266

Query: 832  ---------------GAHSPRAGS------ISPGSPPYPQSRKLSYEIPTEEGGDRYPLP 870
                           G + P A        ++P  PP P  R L+    +  G    PLP
Sbjct: 267  ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326

Query: 871  GHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQG 930
            GHL S   +       P    +GP    TL  SP   P ++SS  + P    ++SS    
Sbjct: 327  GHLPSPHAMGQGMGGLPPGPEKGP----TLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382

Query: 931  KESTRRQDTRSPTSAP---TQRLS--PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVS 985
              ++    + S +++P   +Q L   P    PP S + + + P+    S P     S   
Sbjct: 383  AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP 442

Query: 986  PTFPPSSPSDWPQERSPGGH--SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLT 1043
            P  PP           PG    S GA   +  P +     H   Q  +            
Sbjct: 443  PPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ--- 499

Query: 1044 PVPSQMPWLVASPEPPQSSPTP--------AFPLAASYDTNGLSQPPLPEKRHLPGPG-- 1093
                Q     + P PP + P P        A P A S     L +P  P   HLP P   
Sbjct: 500  ---QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL-RPYPPGPAHLPPPHSQ 555

Query: 1094 ---QQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPE------PP------TQESQS 1138
                Q GP GP  +SS     S      P    +  Q P+      PP      +  + S
Sbjct: 556  VSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615

Query: 1139 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPP---- 1194
             V     +S   YK            +   PGA+       ++     + +  TPP    
Sbjct: 616  TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG 675

Query: 1195 --PSAQPWKGDPVEQLVRHF-LIETGPKGV-KIKGCPSEPYFGSLSALVSQHSISPISLP 1250
              P A P    P    V    L   GP G+  +   P+ P  G            P+S  
Sbjct: 676  TSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASG-----------PPLSAT 724

Query: 1251 CCLRIPSKDPLEETPEAPVP 1270
               + P+++   ETPE+PVP
Sbjct: 725  QIKQEPAEE--YETPESPVP 742



 Score = 31.2 bits (69), Expect = 7.4
 Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 12/124 (9%)

Query: 433 SSSPEKIKGSTP-------RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTR 485
           +SSP   K ++P       +  PS       T P  +  S  +F         G+ +   
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT-SPPA 680

Query: 486 GPLDGSPYAQVQRPPRQTPPAPS--PEPPPPPMLSVSSDSGHSSTLTTEPAA--ESPGRP 541
           GP    P +    P    P  PS  P  PPPP    S     ++ +  EPA   E+P  P
Sbjct: 681 GPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESP 740

Query: 542 PPTA 545
            P A
Sbjct: 741 VPPA 744



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 15/48 (31%), Positives = 22/48 (45%)

Query: 500 PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAE 547
           P   PPA S  P PP     SS S  S+  ++  ++ S    P  A++
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 129/501 (25%), Positives = 169/501 (33%), Gaps = 55/501 (10%)

Query: 665  PPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAG 724
            P   G PA   F   A            G PA  P P        PT     L   +  G
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK-----GAPTTPAATLPSPK-GG 1070

Query: 725  EGWASEAGKPLLHPVRPGHPLPLLLPAC-GHHHAPMPDYSCLKPPKAG--EEGHEGCSYT 781
                S  G P      P  P P   PA      APMP  +    PK G     H+G   T
Sbjct: 1071 PATPSLKGAPTPPAATP--PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128

Query: 782  MC-----PEGRY------GHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPS 830
                   P+G        G P  PA    S  G + +  P       +   P    G  +
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLP------GHLASAGPLASAES 884
            P   SP+    +P + P   S K     P+ +G    P        G LA+  P  +  +
Sbjct: 1189 P---SPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243

Query: 885  LEPVSWREGPSGHSTLPRSPRDAP----CSASSELSGPSTPLHTSSPVQGKESTRRQDTR 940
              P +    P G    P  P+ AP     +  S   G +TP H  +P     +       
Sbjct: 1244 --PAATPPSPKGGPATP-PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300

Query: 941  SPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQER 1000
              TS P    +P  A PP  +   G  P  P G+ P P A +P SP   P+ P+  P   
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPP--PKGA-PTPPAVTPPSPKGTPTLPATTPS-- 1355

Query: 1001 SPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVA-SPEPP 1059
            S GG +  +S   P P   P    +   GP   P SP   P  P P   P   A  P  P
Sbjct: 1356 SKGGPTTPSSKEGPTP---PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412

Query: 1060 QSSP-TPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFA 1118
            + +P TP     A+  + G   PP      L        P G      PA   S      
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-----GPATPSSKGDPTL 1467

Query: 1119 PLLSDNVPQTPEPPTQESQSN 1139
            P ++   P+ P  P Q + S+
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSS 1488



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 183/737 (24%), Positives = 246/737 (33%), Gaps = 111/737 (15%)

Query: 423  PFQASVEFVFSSSPEKIKGS-TPRNDP-SVSVDYNTTEPAVRWDSYENFNQHHEDSVDGS 480
            P QA    + SSSP+K + +  P+  P S S     T PA    S +             
Sbjct: 905  PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG------------ 952

Query: 481  LTHTRGPLDGSPYAQVQRPPRQTPPAP-----SPEP---PPPPMLSVSSDSGHSSTLTTE 532
                 GP   SP      PP  TPP+P     +P P   P PP  +  S  G  +T + +
Sbjct: 953  -----GPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006

Query: 533  PAAESPGRPPPTAAERQELDRLLGGCGVASGG-----RGAGRETAI------LDDEEQPT 581
             A   P   PP+            G            +G+   T +            P+
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066

Query: 582  VGGGPHLGVYPG-HRPGLSRHCSCRQGYREPCGVPNGGYYRPEGT--LERRRLAYGGYEG 638
              GGP      G   P  +   S + G   P   P G    P  T    +  LA   ++G
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPS--PKGAPMPPAATPPSPKGGLATPPHKG 1124

Query: 639  SPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALY 698
            +P   A      +        G    PP  G P T      +P           GL    
Sbjct: 1125 APTTPAATPPSPK--------GGLATPPPKGAPTTPAATPPSP---------KGGLATPP 1167

Query: 699  PCPACEEKLALPTAALYGLRLEREAGEGWASEAGKP-----LLHPVRPGHP-LPLLLPAC 752
            P  A     A P +   GL      G      A  P     L  P   G P  P   P  
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227

Query: 753  --GHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGG--AVPSY 808
              G    P P       P A     +G   T  P+G    P  PA    S  G  A P +
Sbjct: 1228 PKGGLATPSPK-GAPTTPAATPPSPKGGPATPPPKGA---PTPPAATPPSLKGGLATPPH 1283

Query: 809  ----CPAYGRVPHSCGSPGEG--RGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEI--PT 860
                 PA    P   G P     +G P+P A +P +   SPG+PP P+       +  P+
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP-PKGAPTPPAVTPPS 1342

Query: 861  EEGGDRYPLPGHLASAGPLASAESLEPVSWREGPS---GHSTLPRSPRDAPCSASSELSG 917
             +G    P     +  GP   +    P      PS   G +  P SP+  P   S +   
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK-GD 1401

Query: 918  PSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPP-VSQAGTGKAPELPSGSGP 976
            P++P     P+  K++     TR   + P    S G+  PP V+     KAP   +  G 
Sbjct: 1402 PTSP--AVIPLSPKKAPATPVTREGAATP----SKGDLTPPAVTPVSLKKAPATSAPKG- 1454

Query: 977  EPLAPS----PVSPTFPPSSPSDWPQERSPG-GHSDGASPRSPVPTTLPGLRHAPWQGPR 1031
             P  PS    P  P   P SP + P  +      S   +P +P P   P L       P 
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL-------PA 1507

Query: 1032 GPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKR-HLP 1090
              P SP   P TP   + P  +A      S  TPA               P P+K   +P
Sbjct: 1508 VIPSSPKEVPATPSSRRDP--IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565

Query: 1091 GPGQQPGPWGPEQASSP 1107
             P + P     ++ASSP
Sbjct: 1566 TPKEAPATPSSKEASSP 1582



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 84/326 (25%), Positives = 121/326 (37%), Gaps = 50/326 (15%)

Query: 815  VPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLA 874
            +P S  SP        PG       S +    P   S K   E PTE+ G          
Sbjct: 730  IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK---ECPTEDSG---------- 776

Query: 875  SAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPL-HTSSPVQGKES 933
            ++   +S  +L  ++    P G S  P++ R      S+   GP TP+ + SSPV   E+
Sbjct: 777  ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA---GPDTPIGNLSSPVSPVEA 833

Query: 934  T----------RRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSP 983
            +            +D+ + T +PT     G   P      + K   LP    P    PS 
Sbjct: 834  SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP---TPSV 890

Query: 984  VSPTFPPSSPSDWPQERSPGGHSDGASPR----SPVPTTLPGL---RHAPWQGPRGPPDS 1036
            V+  FP   P+    +++P      +SP+    +P P  +P     + AP   P   P S
Sbjct: 891  VNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPS 949

Query: 1037 PDGSPLTPVPSQMPWLVASPEP----------PQSSPTPAFPLAASYDTNGLSQPPLPEK 1086
            P G P TP P   P   A+  P          P+ +PTP  P A      G    P P+ 
Sbjct: 950  PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP--PAATPPSPKGGPATPSPKG 1007

Query: 1087 RHLPGPGQQPGPWGPEQASSPARGIS 1112
               P     P P G   A+   +G S
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGAS 1033



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 92/373 (24%), Positives = 132/373 (35%), Gaps = 49/373 (13%)

Query: 767  PPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTY------SYGGAVPSYCPAYGRVPHSCG 820
            P K G  G +       P G    P  P   ++      S+ G+  S  PA    P    
Sbjct: 809  PTKKGSAGPD------TPIGNLSSPVSPVEASFLPENSLSFQGSKDS--PATTHSP---- 856

Query: 821  SPGEGRGYPSPGAH---SPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGH----- 872
            +P   +G P+P A    SP+  ++ P   P P    L    P  + G   P P       
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL----PFPKEGPATPAPKQAPALS 912

Query: 873  LASAGPLASAESLEPV------SWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHT-S 925
            + S+ P  +  +  P       S +  P+  +  P SP+  P + S + + P+ P  T  
Sbjct: 913  MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA-PTPPAATPP 971

Query: 926  SPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVS 985
            SP  G  +   +   +P +A       G A P    A T  A   PS  G     P P  
Sbjct: 972  SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031

Query: 986  PTFPPSSPSDWPQERSPGGHSDGASPRSPVPT--------TLPGLRHAPWQGPRGPPDSP 1037
             + PP++    P+           +P +P  T          P L+ AP   P   P SP
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP-TPPAATPPSP 1090

Query: 1038 DGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPG 1097
             G P TP P   P +  +  PP      A P      T   + PP P K  L  P  +  
Sbjct: 1091 KGGPATPSPKGAP-MPPAATPPSPKGGLATPPHKGAPTTPAATPPSP-KGGLATPPPKGA 1148

Query: 1098 PWGPEQASSPARG 1110
            P  P       +G
Sbjct: 1149 PTTPAATPPSPKG 1161



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 162/658 (24%), Positives = 221/658 (33%), Gaps = 109/658 (16%)

Query: 490  GSPYAQ-----VQRPPRQTPPAPSPEP---------PPPPMLSVSSDSGHSSTLTTEPAA 535
            GSP A         PP  TPP+P   P         P  P  ++ S  G  +T + + A 
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080

Query: 536  ESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGV--YPG 593
              P   PP+           GG    S  +GA    A      +  +   PH G    P 
Sbjct: 1081 TPPAATPPSPK---------GGPATPSP-KGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130

Query: 594  HRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRR--LAYGGYEGSPQGYAEASMEKR 651
              P      S + G   P   P G    P  T    +  LA    +G+P   A      +
Sbjct: 1131 ATPP-----SPKGGLATP--PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183

Query: 652  RLCRSLSEGLYPYPPEMGKPAT-GDFGYRAPGYREVVILEDP-----GLPALYPCPACEE 705
                + S    P  P    P+  G     +P          P     GL    P  A   
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243

Query: 706  KLALPTAALYGLRLEREAGEGWASEAGKPLLH-----PVRPGHPLPLLL--PACGHHHAP 758
              A P +   G       G      A  P L      P   G P P ++  P+     A 
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303

Query: 759  MPDYSCLKPPKAGEEGHEGCSYTMCPEGR-----------YGHPGYPALVTYSYGGAV-- 805
             P      PP A     +G   T  P+G             G P  PA    S GG    
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363

Query: 806  --------PSYCPAY-GRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSY 856
                    P+  P++ G    +  SP  G   PSP    P + ++ P SP    +  ++ 
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG-DPTSPAVIPLSPKKAPATPVTR 1422

Query: 857  E-IPTEEGGDRYP---LPGHLASAGPLASAESLEPV--SWREGPSGHSTLPRSPRDAPC- 909
            E   T   GD  P    P  L  A P  SA    P   S +  P+  +  P SP++ P  
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKA-PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481

Query: 910  ----SASSELSGPSTPLHTSSP------------VQGKESTRRQDTRSPTSAPTQRLSPG 953
                ++SS    P+TP    +P            V    S+RR D  +PT+    + +P 
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR-DPIAPTATLLSKKTPA 1540

Query: 954  EALPPVSQAGTGKAPELPSGSGPEPLAPSPV-SPTFPPSSPSDWPQERSPGGHSDGASPR 1012
               P   +A    A  +PS     P  P+P  +P  P S  +  P   +P  +    SP+
Sbjct: 1541 TLAP--KEALIPPAMTVPSPK-KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597

Query: 1013 S---PVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQS---SPT 1064
                P   T P  + AP   P   P SP+  P TP P   P   + P  P S   SPT
Sbjct: 1598 ELLIPPAVTSPSPKEAPTP-PAVTPPSPEKGPATPAPKGTP--TSPPVTPSSLKDSPT 1652



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 136/569 (23%), Positives = 182/569 (31%), Gaps = 117/569 (20%)

Query: 491  SPYAQVQRPPRQTPPAPSPEP--------PPPPMLSVSSDSGHSSTLTTEPAAES----- 537
            SP      PP  TPP+P   P        P PP ++  S  G  +   T P+++      
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363

Query: 538  ---PGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGH 594
                G  PP A    +        G A       R  AI   +  PT          P  
Sbjct: 1364 SSKEGPTPPAATPSHK-------GGPAMTPPSPKRGPAIPSPKGDPTS---------PAV 1407

Query: 595  RPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLE---RRRLAYGGYEGSPQGYAEASMEKR 651
             P   +        RE    P+ G   P        ++  A    +G P   A  S +  
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP---ATPSSKGD 1464

Query: 652  RLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPC--------PAC 703
                +++      PP   + AT     +AP       +  P LPA+ P         P+ 
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPA--TPAPMGAPTLPAVIPSSPKEVPATPSS 1522

Query: 704  EEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYS 763
                  PTA L   +         A+ A K  L P     P P   PA      P P   
Sbjct: 1523 RRDPIAPTATLLSKKTP-------ATLAPKEALIPPAMTVPSPKKTPAI-----PTP--- 1567

Query: 764  CLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPG 823
              K   A     E  S        Y   G P+        AV S  P     P +   P 
Sbjct: 1568 --KEAPATPSSKEASSPPAVTPSTY--KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623

Query: 824  EGRGYPSPGAH-SPRAGSISPGS----PPYPQSR--KLSYEIPTEEGGDRYPLPGHLASA 876
              +G  +P    +P +  ++P S    P  P S   K+   +P    G    LP   A  
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG----LP---AKK 1676

Query: 877  GPLASAESL-------EPVSWREGPSGHSTLPRSPRDAP-CSASSELSGPSTPLHTSSPV 928
            GP A  E L        P+       G  T   S    P C   S  +G   PL T +P 
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736

Query: 929  Q----GKESTRRQDTRSPTSAPTQRLSPGEA--------------LPPVSQAGTGKAPEL 970
                  K+S++    +  + +P   L+P E+              LP    A    AP  
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796

Query: 971  PSGSGPEPLAPSPVSPT------FPPSSP 993
            P      PLAPSPV PT      F PSSP
Sbjct: 1797 PVSL---PLAPSPV-PTLPPKQQFLPSSP 1821



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 99/412 (24%), Positives = 160/412 (38%), Gaps = 66/412 (16%)

Query: 843  PGSPPYPQSRKLS-------YEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPS 895
            P SPP P    L         + PT++  D   +P  L  A P + A++   ++ ++ P+
Sbjct: 504  PVSPPLPDPEDLKNLPSSVLVKFPTQK--DLQTVPASLEGA-PFSPAQA--GLTTKKDPT 558

Query: 896  GHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL---SP 952
                +  +P+++P S  S  S P  PL   + +  K          P S+ T  L   S 
Sbjct: 559  VLPLVQAAPKNSP-SFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSS 617

Query: 953  GEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPT---FPPSS--PSDWPQERSPGG--H 1005
               +   S AG       P  +GP  L  S ++PT   FP  S  P+      + G   +
Sbjct: 618  ASVIKTDSYAG-------PDSAGPL-LKSSLITPTVAAFPLESADPAGVAPTTAKGTSTY 669

Query: 1006 SDGASPRSPVPTTLPGLRHAPWQGPRGP----PDSPDGSPLTPVPSQ----MPWLVASPE 1057
            +  ASP      +L    H   +G        P + +  P+ P P      +  LV +PE
Sbjct: 670  TTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE 729

Query: 1058 PPQSSPTPAFPLA----ASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISH 1113
             P+S P+P+ P A     +   +G+S            P + P       A++ ++G   
Sbjct: 730  IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP-VASSPKECPTEDSGASATASSKGTLT 788

Query: 1114 HV--TFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGA 1171
            ++  + +PL     PQT  PPT++  +      DT        +S  +A          +
Sbjct: 789  YLADSPSPLGVSVSPQTKRPPTKKGSAG----PDTPIGNLSSPVSPVEA----------S 834

Query: 1172 FLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI 1223
            FL  +S SFQG+        +P P +   KG P    V        PKGV +
Sbjct: 835  FLPENSLSFQGSKDSPATTHSPTPPSP--KGAPTPSAV----TPLSPKGVTL 880



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 99/412 (24%), Positives = 148/412 (35%), Gaps = 52/412 (12%)

Query: 868  PLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELS---GPSTPLHT 924
            P P    +  P++SA S+     + GP+       +P+  P SA+++ S    PST   T
Sbjct: 17   PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76

Query: 925  SSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL--------PSGSGP 976
               V   +S+        T+       P    PP+S A    A  +        PS S P
Sbjct: 77   PLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAP 136

Query: 977  ---EPLAPSPV--SPTFPPSSPSDWPQ--ERSPGGHSDGASPRSP--VPTTLPGLRHAPW 1027
                 LAP  V  S  FPP+  +  P       G     ++P +P    T L  +     
Sbjct: 137  LALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVV 196

Query: 1028 QGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPE-- 1085
              P+G P  P       + S +P+   +P     S   + P      T  ++ P + +  
Sbjct: 197  PNPKGTPSPP------CIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTT 250

Query: 1086 -KRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV----PQTPEPPTQESQSNV 1140
                L  P Q PG    +   SP   +S      P+++ +     P TP P    S  + 
Sbjct: 251  ISSVLISP-QNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTP-PDFPISLGSH 308

Query: 1141 KFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPW 1200
                  S F     L +    AL    DP    I   HS  GA   + +   PP    P 
Sbjct: 309  LAPLHQSSFGSVQLLGQTGPSAL---SDPTVKTISVDHSSTGASYPSQRSVIPP---LPS 362

Query: 1201 KGDPVEQLVRHF-----LIETGPKGVKIKGC-PSEPYFGSLSALVSQHSISP 1246
            + + V   V  F      ++ GP  +    C PS    GSL+   S  S+SP
Sbjct: 363  RNEVVPATVAAFPVVAPSVDKGPSTISSITCSPS----GSLNVATS-FSLSP 409



 Score = 35.0 bits (79), Expect = 0.51
 Identities = 86/394 (21%), Positives = 136/394 (34%), Gaps = 53/394 (13%)

Query: 894  PSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG 953
            PS +  +P +    P  A S   GPST    +    G  +     + SPT++   + SP 
Sbjct: 361  PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420

Query: 954  E-------ALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 1006
                    A  PVS  GT         + P  +A +P + TF  ++    P    P  + 
Sbjct: 421  ATYHYPLVAQMPVSSVGTTPLVV----TNPCTIAAAPTT-TFEVATCVSPPMSSGPISNI 475

Query: 1007 DGASP----RSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1062
            +  SP     +PV    P  + A        P  PD   L  +PS +  LV  P      
Sbjct: 476  EPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSV--LVKFPTQKDLQ 533

Query: 1063 PTPAFPLAASYD--TNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFA-P 1119
              PA    A +     GL+    P    L     +  P     +SSP   +S   T A  
Sbjct: 534  TVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK 593

Query: 1120 LLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHS 1179
             L + +P      +  S   V                 + + +++K          DS++
Sbjct: 594  SLGEPLPIGKPASSMTSPLGV-----------------NSSASVIK---------TDSYA 627

Query: 1180 FQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYF-GSLSAL 1238
               + G  LK +   P+   +   P+E      +  T  KG       + P+  G++S  
Sbjct: 628  GPDSAGPLLKSSLITPTVAAF---PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA 684

Query: 1239 VSQHSISPISLPCCLRIPSKDPLEETPEAPVPTN 1272
               H +   +L     +P+    E  P AP P N
Sbjct: 685  PKNHPVKEGTLTTLPLVPTAS--ENCPVAPSPQN 716



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 9/80 (11%)

Query: 488  LDGSPYAQVQRPPRQTPPAPSPE-----PPPPPMLSVSSDSGHSSTLTTEPAAESPGRPP 542
            L  SP   ++ P +   PA   E     PP P    +S      S L   P  +S G P 
Sbjct: 1817 LPSSPGLVLESPSKPLAPADEDELLPLIPPEP----ISGGVPFQSVLVNMPTPKSAGIPV 1872

Query: 543  PTAAERQELDRLLGGCGVAS 562
            PT + +Q + +   G G  S
Sbjct: 1873 PTPSAKQPVTKNNKGSGTES 1892


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)

Query: 830  SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 887
            +P   +P     +P +P  P P + K +   P E      P P       P    E    
Sbjct: 228  TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 281

Query: 888  VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 947
             +    P+   + P +P++ P   + +   P+TP   + P   KE T       PT+   
Sbjct: 282  TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 329

Query: 948  QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 1007
                      P   A T K P   +   P P AP   +PT P       P+E +P    +
Sbjct: 330  ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379

Query: 1008 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1064
             +  +P+ P PTT    + AP       P +   +P TP  PS       +P  P+  P 
Sbjct: 380  PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 435

Query: 1065 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1117
            P  P   +  T     P  P+       K+  P   ++P P  P++ ++P        T 
Sbjct: 436  PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 494

Query: 1118 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1177
               L+   P+ P P T E  +     + T     +P  +  +A A    K+P        
Sbjct: 495  PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 548

Query: 1178 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1233
                       K   P    +P    P E         T PKG       +  P+ P   
Sbjct: 549  --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 594

Query: 1234 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1291
            +   L    +  P S  C    P+  K     TP+ P PT     A    +G A + L  
Sbjct: 595  APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654

Query: 1292 TSVETESLTGPQAVA----RASSAALSCSPRPT 1320
             +  T     P+ +A    +  ++  S  P PT
Sbjct: 655  PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 888
            P   +P+  + +    P P + K +   P E      + P P       P    E     
Sbjct: 270  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329

Query: 889  SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 941
                 P+     P +P++        P   + +   P+TP   +     + S       +
Sbjct: 330  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389

Query: 942  PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 999
            PT+  +   +  E  P  +++   T K P   +   P P  P   +PT P       P+E
Sbjct: 390  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449

Query: 1000 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1045
             +P    + A          +P+ P PTT      AP    +  P +P+     +P  P 
Sbjct: 450  PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 507

Query: 1046 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1100
            P+    L   +PE P  +    P P  P AA+ +T     P  P K   P   ++P P  
Sbjct: 508  PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 566

Query: 1101 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1159
            P E A +  +G     T    L +  P TP+ P  +  +     + TS    KP  +  +
Sbjct: 567  PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621

Query: 1160 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1219
              A    K+P     ++        G A      P    P K  P E      L  T  K
Sbjct: 622  GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 674

Query: 1220 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1271
            G       K  P+ P     +A  +    +P +         K P   TPE P PT
Sbjct: 675  GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 719



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)

Query: 829  PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 883
            PSP      A + +  +P     P P + K +   P E      P P       P    E
Sbjct: 380  PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 433

Query: 884  SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 942
                   +  P+      P +P++ P   +++   P+TP   + P   KE+      +  
Sbjct: 434  PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 491

Query: 943  TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 1002
             + P ++L+P     P        AP  P    P P  P   +PT P ++  + P+E +P
Sbjct: 492  PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 548

Query: 1003 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1062
                   +P+ P PTT      AP       P +P G+  T +    P     P P + +
Sbjct: 549  ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600

Query: 1063 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1120
            PT    P + + D       P   K   P   ++P P  P E A +  +G     T    
Sbjct: 601  PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 651

Query: 1121 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1169
            L +  P TP+ P  +  +       TS    KP  +  +  A    K+P
Sbjct: 652  LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 700



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)

Query: 851  SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 910
            S K +  I      D  P    LA   P A   +  P       +     P +P++ P S
Sbjct: 172  SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 226

Query: 911  ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 966
             + +   P+T    S+P   KE        +PT+    APT    P    P      T K
Sbjct: 227  TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 284

Query: 967  --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1019
              AP     +   P  P+P +P  P P++P +     P+E +P       +P+ P PTT 
Sbjct: 285  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 338

Query: 1020 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1079
                      P  P +    +P  P P+         EP  ++P    P      +    
Sbjct: 339  E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 385

Query: 1080 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1138
            + P P   +  P   ++P P   + A +  +  S   T  P  +   P+ P P T +  +
Sbjct: 386  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 443

Query: 1139 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1197
                 +       +P  +  +  A    K+P     +++     A     K+  T P   
Sbjct: 444  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 498

Query: 1198 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1257
             P   +         L  T P+       P EP      A  +  + +P +         
Sbjct: 499  APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 551

Query: 1258 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1314
            K+P   TP+ P PT     A    +G A + L   +  T     P+ +A  ++    + +
Sbjct: 552  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611

Query: 1315 C-SPRPT 1320
            C  P PT
Sbjct: 612  CDKPAPT 618



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 890
            P   +P+A +  P +P  P         PT         P   A   P  +A    P + 
Sbjct: 530  PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 583

Query: 891  REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 950
            +E      T P+ P      A  EL+  +T   TS+       T  + T   T       
Sbjct: 584  KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 634

Query: 951  SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 1007
            +P E  P   +       + P+ + P+  AP  ++PT    P S+ SD P   +P   + 
Sbjct: 635  TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 693

Query: 1008 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1066
              +P+ P PTT           P+ P P +P+  P T      P     P     SP  +
Sbjct: 694  PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 742

Query: 1067 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1113
             P  ++  T     N   +P +P  +        P    PE  ++          R    
Sbjct: 743  TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 795

Query: 1114 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1149
              T AP ++     T E  T+       +Q      QDT+ F
Sbjct: 796  TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 837



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)

Query: 400 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 453
           T  GP LT PK+       + A T  + P   +++    ++P++   +T ++ P+   + 
Sbjct: 204 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 262

Query: 454 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 511
               T EPA             E +   + +    P + +P    ++P   TP  P+P  
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 321

Query: 512 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 548
           P  P  +   +   +   T EPA  +P  P PTA ++
Sbjct: 322 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 355



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 47/236 (19%), Positives = 74/236 (31%), Gaps = 27/236 (11%)

Query: 898  STLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP 957
            ST P+     P +    L   S     +S    KE+T   +T+  T+   Q  + G+   
Sbjct: 113  STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT--VETKETTTTNKQTSTDGKEK- 169

Query: 958  PVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPT 1017
                  T  A E  S         +P S      +P      + P       +P+ P PT
Sbjct: 170  ------TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPT 219

Query: 1018 TLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNG 1077
            T              P +    +P  P P+ +     +P+ P  + T + P         
Sbjct: 220  T--------------PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 265

Query: 1078 LSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPT 1133
             ++ P P     P P     P      S+P        T     +   P+ P P T
Sbjct: 266  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 321



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +        P++T P    EP P              T   +PA  +P  P
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 716

Query: 542 PPTAAE 547
           PPT +E
Sbjct: 717 PPTTSE 722



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 17/66 (25%), Positives = 27/66 (40%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +P       P++       EP P  + S  +     +  TT+ A  +P  P
Sbjct: 203 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 262

Query: 542 PPTAAE 547
            PT  +
Sbjct: 263 APTTTK 268



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 538
           T T+ P   SP    +  P  T  AP+    P P  + S+ +     S T T EPA  +P
Sbjct: 375 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431

Query: 539 GRPPPTAAER 548
             P PT  ++
Sbjct: 432 KEPAPTTPKK 441



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)

Query: 480 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 539
           S T T+ P   +P    + P   TP  P+P  P  P  +   +   + T T +PA  +P 
Sbjct: 419 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 472

Query: 540 RPPPT 544
            P PT
Sbjct: 473 EPAPT 477



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 499 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 544
           P     PAP+ P+ P P  L+ ++  G +ST + +PA  +P    PT
Sbjct: 649 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)

Query: 830  SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 887
            +P   +P     +P +P  P P + K +   P E      P P       P    E    
Sbjct: 269  TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 322

Query: 888  VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 947
             +    P+   + P +P++ P   + +   P+TP   + P   KE T       PT+   
Sbjct: 323  TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 370

Query: 948  QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 1007
                      P   A T K P   +   P P AP   +PT P       P+E +P    +
Sbjct: 371  ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420

Query: 1008 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1064
             +  +P+ P PTT    + AP       P +   +P TP  PS       +P  P+  P 
Sbjct: 421  PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 476

Query: 1065 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1117
            P  P   +  T     P  P+       K+  P   ++P P  P++ ++P        T 
Sbjct: 477  PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 535

Query: 1118 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1177
               L+   P+ P P T E  +     + T     +P  +  +A A    K+P        
Sbjct: 536  PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 589

Query: 1178 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1233
                       K   P    +P    P E         T PKG       +  P+ P   
Sbjct: 590  --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 635

Query: 1234 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1291
            +   L    +  P S  C    P+  K     TP+ P PT     A    +G A + L  
Sbjct: 636  APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695

Query: 1292 TSVETESLTGPQAVA----RASSAALSCSPRPT 1320
             +  T     P+ +A    +  ++  S  P PT
Sbjct: 696  PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 888
            P   +P+  + +    P P + K +   P E      + P P       P    E     
Sbjct: 311  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370

Query: 889  SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 941
                 P+     P +P++        P   + +   P+TP   +     + S       +
Sbjct: 371  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430

Query: 942  PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 999
            PT+  +   +  E  P  +++   T K P   +   P P  P   +PT P       P+E
Sbjct: 431  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490

Query: 1000 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1045
             +P    + A          +P+ P PTT      AP    +  P +P+     +P  P 
Sbjct: 491  PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 548

Query: 1046 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1100
            P+    L   +PE P  +    P P  P AA+ +T     P  P K   P   ++P P  
Sbjct: 549  PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 607

Query: 1101 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1159
            P E A +  +G     T    L +  P TP+ P  +  +     + TS    KP  +  +
Sbjct: 608  PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662

Query: 1160 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1219
              A    K+P     ++        G A      P    P K  P E      L  T  K
Sbjct: 663  GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 715

Query: 1220 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1271
            G       K  P+ P     +A  +    +P +         K P   TPE P PT
Sbjct: 716  GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 760



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)

Query: 829  PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 883
            PSP      A + +  +P     P P + K +   P E      P P       P    E
Sbjct: 421  PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 474

Query: 884  SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 942
                   +  P+      P +P++ P   +++   P+TP   + P   KE+      +  
Sbjct: 475  PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 532

Query: 943  TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 1002
             + P ++L+P     P        AP  P    P P  P   +PT P ++  + P+E +P
Sbjct: 533  PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 589

Query: 1003 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1062
                   +P+ P PTT      AP       P +P G+  T +    P     P P + +
Sbjct: 590  ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641

Query: 1063 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1120
            PT    P + + D       P   K   P   ++P P  P E A +  +G     T    
Sbjct: 642  PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 692

Query: 1121 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1169
            L +  P TP+ P  +  +       TS    KP  +  +  A    K+P
Sbjct: 693  LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 741



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)

Query: 851  SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 910
            S K +  I      D  P    LA   P A   +  P       +     P +P++ P S
Sbjct: 213  SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 267

Query: 911  ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 966
             + +   P+T    S+P   KE        +PT+    APT    P    P      T K
Sbjct: 268  TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 325

Query: 967  --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1019
              AP     +   P  P+P +P  P P++P +     P+E +P       +P+ P PTT 
Sbjct: 326  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 379

Query: 1020 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1079
                      P  P +    +P  P P+         EP  ++P    P      +    
Sbjct: 380  E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 426

Query: 1080 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1138
            + P P   +  P   ++P P   + A +  +  S   T  P  +   P+ P P T +  +
Sbjct: 427  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 484

Query: 1139 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1197
                 +       +P  +  +  A    K+P     +++     A     K+  T P   
Sbjct: 485  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 539

Query: 1198 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1257
             P   +         L  T P+       P EP      A  +  + +P +         
Sbjct: 540  APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 592

Query: 1258 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1314
            K+P   TP+ P PT     A    +G A + L   +  T     P+ +A  ++    + +
Sbjct: 593  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652

Query: 1315 C-SPRPT 1320
            C  P PT
Sbjct: 653  CDKPAPT 659



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 890
            P   +P+A +  P +P  P         PT         P   A   P  +A    P + 
Sbjct: 571  PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 624

Query: 891  REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 950
            +E      T P+ P      A  EL+  +T   TS+       T  + T   T       
Sbjct: 625  KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675

Query: 951  SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 1007
            +P E  P   +       + P+ + P+  AP  ++PT    P S+ SD P   +P   + 
Sbjct: 676  TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 734

Query: 1008 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1066
              +P+ P PTT           P+ P P +P+  P T      P     P     SP  +
Sbjct: 735  PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783

Query: 1067 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1113
             P  ++  T     N   +P +P  +        P    PE  ++          R    
Sbjct: 784  TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 836

Query: 1114 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1149
              T AP ++     T E  T+       +Q      QDT+ F
Sbjct: 837  TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 878



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)

Query: 400 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 453
           T  GP LT PK+       + A T  + P   +++    ++P++   +T ++ P+   + 
Sbjct: 245 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 303

Query: 454 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 511
               T EPA             E +   + +    P + +P    ++P   TP  P+P  
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 362

Query: 512 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 548
           P  P  +   +   +   T EPA  +P  P PTA ++
Sbjct: 363 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 396



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 47/236 (19%), Positives = 74/236 (31%), Gaps = 27/236 (11%)

Query: 898  STLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALP 957
            ST P+     P +    L   S     +S    KE+T   +T+  T+   Q  + G+   
Sbjct: 154  STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT--VETKETTTTNKQTSTDGKEK- 210

Query: 958  PVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPT 1017
                  T  A E  S         +P S      +P      + P       +P+ P PT
Sbjct: 211  ------TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPT 260

Query: 1018 TLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNG 1077
            T              P +    +P  P P+ +     +P+ P  + T + P         
Sbjct: 261  T--------------PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 306

Query: 1078 LSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPT 1133
             ++ P P     P P     P      S+P        T     +   P+ P P T
Sbjct: 307  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 362



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +        P++T P    EP P              T   +PA  +P  P
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 757

Query: 542 PPTAAE 547
           PPT +E
Sbjct: 758 PPTTSE 763



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 17/66 (25%), Positives = 27/66 (40%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +P       P++       EP P  + S  +     +  TT+ A  +P  P
Sbjct: 244 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 303

Query: 542 PPTAAE 547
            PT  +
Sbjct: 304 APTTTK 309



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 538
           T T+ P   SP    +  P  T  AP+    P P  + S+ +     S T T EPA  +P
Sbjct: 416 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472

Query: 539 GRPPPTAAER 548
             P PT  ++
Sbjct: 473 KEPAPTTPKK 482



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)

Query: 480 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 539
           S T T+ P   +P    + P   TP  P+P  P  P  +   +   + T T +PA  +P 
Sbjct: 460 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 513

Query: 540 RPPPT 544
            P PT
Sbjct: 514 EPAPT 518



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 499 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 544
           P     PAP+ P+ P P  L+ ++  G +ST + +PA  +P    PT
Sbjct: 690 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)

Query: 830  SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 887
            +P   +P     +P +P  P P + K +   P E      P P       P    E    
Sbjct: 321  TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 374

Query: 888  VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 947
             +    P+   + P +P++ P   + +   P+TP   + P   KE T       PT+   
Sbjct: 375  TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 422

Query: 948  QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 1007
                      P   A T K P   +   P P AP   +PT P       P+E +P    +
Sbjct: 423  ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 472

Query: 1008 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1064
             +  +P+ P PTT    + AP       P +   +P TP  PS       +P  P+  P 
Sbjct: 473  PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 528

Query: 1065 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1117
            P  P   +  T     P  P+       K+  P   ++P P  P++ ++P        T 
Sbjct: 529  PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 587

Query: 1118 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1177
               L+   P+ P P T E  +     + T     +P  +  +A A    K+P        
Sbjct: 588  PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 641

Query: 1178 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1233
                       K   P    +P    P E         T PKG       +  P+ P   
Sbjct: 642  --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 687

Query: 1234 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1291
            +   L    +  P S  C    P+  K     TP+ P PT     A    +G A + L  
Sbjct: 688  APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747

Query: 1292 TSVETESLTGPQAVA----RASSAALSCSPRPT 1320
             +  T     P+ +A    +  ++  S  P PT
Sbjct: 748  PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 888
            P   +P+  + +    P P + K +   P E      + P P       P    E     
Sbjct: 363  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422

Query: 889  SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 941
                 P+     P +P++        P   + +   P+TP   +     + S       +
Sbjct: 423  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482

Query: 942  PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 999
            PT+  +   +  E  P  +++   T K P   +   P P  P   +PT P       P+E
Sbjct: 483  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542

Query: 1000 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1045
             +P    + A          +P+ P PTT      AP    +  P +P+     +P  P 
Sbjct: 543  PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 600

Query: 1046 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1100
            P+    L   +PE P  +    P P  P AA+ +T     P  P K   P   ++P P  
Sbjct: 601  PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 659

Query: 1101 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1159
            P E A +  +G     T    L +  P TP+ P  +  +     + TS    KP  +  +
Sbjct: 660  PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714

Query: 1160 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1219
              A    K+P     ++        G A      P    P K  P E      L  T  K
Sbjct: 715  GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 767

Query: 1220 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1271
            G       K  P+ P     +A  +    +P +         K P   TPE P PT
Sbjct: 768  GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 812



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)

Query: 829  PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 883
            PSP      A + +  +P     P P + K +   P E      P P       P    E
Sbjct: 473  PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 526

Query: 884  SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 942
                   +  P+      P +P++ P   +++   P+TP   + P   KE+      +  
Sbjct: 527  PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 584

Query: 943  TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 1002
             + P ++L+P     P        AP  P    P P  P   +PT P ++  + P+E +P
Sbjct: 585  PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 641

Query: 1003 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1062
                   +P+ P PTT      AP       P +P G+  T +    P     P P + +
Sbjct: 642  ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693

Query: 1063 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1120
            PT    P + + D       P   K   P   ++P P  P E A +  +G     T    
Sbjct: 694  PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 744

Query: 1121 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1169
            L +  P TP+ P  +  +       TS    KP  +  +  A    K+P
Sbjct: 745  LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)

Query: 851  SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 910
            S K +  I      D  P    LA   P A   +  P       +     P +P++ P S
Sbjct: 265  SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 319

Query: 911  ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 966
             + +   P+T    S+P   KE        +PT+    APT    P    P      T K
Sbjct: 320  TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 377

Query: 967  --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1019
              AP     +   P  P+P +P  P P++P +     P+E +P       +P+ P PTT 
Sbjct: 378  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 431

Query: 1020 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1079
                      P  P +    +P  P P+         EP  ++P    P      +    
Sbjct: 432  E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 478

Query: 1080 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1138
            + P P   +  P   ++P P   + A +  +  S   T  P  +   P+ P P T +  +
Sbjct: 479  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 536

Query: 1139 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1197
                 +       +P  +  +  A    K+P     +++     A     K+  T P   
Sbjct: 537  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 591

Query: 1198 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1257
             P   +         L  T P+       P EP      A  +  + +P +         
Sbjct: 592  APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 644

Query: 1258 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1314
            K+P   TP+ P PT     A    +G A + L   +  T     P+ +A  ++    + +
Sbjct: 645  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704

Query: 1315 C-SPRPT 1320
            C  P PT
Sbjct: 705  CDKPAPT 711



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 890
            P   +P+A +  P +P  P         PT         P   A   P  +A    P + 
Sbjct: 623  PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 676

Query: 891  REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 950
            +E      T P+ P      A  EL+  +T   TS+       T  + T   T       
Sbjct: 677  KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 727

Query: 951  SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 1007
            +P E  P   +       + P+ + P+  AP  ++PT    P S+ SD P   +P   + 
Sbjct: 728  TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 786

Query: 1008 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1066
              +P+ P PTT           P+ P P +P+  P T      P     P     SP  +
Sbjct: 787  PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 835

Query: 1067 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1113
             P  ++  T     N   +P +P  +        P    PE  ++          R    
Sbjct: 836  TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 888

Query: 1114 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1149
              T AP ++     T E  T+       +Q      QDT+ F
Sbjct: 889  TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 930



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 67/368 (18%), Positives = 116/368 (31%), Gaps = 52/368 (14%)

Query: 809  CPAYGRV---PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD 865
            CP Y       H+  SP   +  P P   S    S +  SP  P  +K    I +EE  +
Sbjct: 56   CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE 115

Query: 866  RYPLPGHLASAGPLASAES---LEPVSWREGPSGHSTLPRS--PRDAPCSASSELSGPST 920
             + +  +  S+   +S+ S   +  +   +  + +  L +    +D   + + +   P  
Sbjct: 116  EHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 175

Query: 921  PL------------------HTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQA 962
            P+                   TS+    K ST      SP     + ++P  +LPP S  
Sbjct: 176  PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST------SPKITTAKPINPRPSLPPNSDT 229

Query: 963  G-----------------TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGH 1005
                              T    +  S  G E    +  + +   +S  D          
Sbjct: 230  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289

Query: 1006 SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP 1065
                +P++   T  P L       P  P +    +P  P P+ +     +P+ P  + T 
Sbjct: 290  P---TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346

Query: 1066 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1125
            + P          ++ P P     P P     P      S+P        T     +   
Sbjct: 347  SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406

Query: 1126 PQTPEPPT 1133
            P+ P P T
Sbjct: 407  PKEPAPTT 414



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)

Query: 400 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 453
           T  GP LT PK+       + A T  + P   +++    ++P++   +T ++ P+   + 
Sbjct: 297 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 355

Query: 454 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 511
               T EPA             E +   + +    P + +P    ++P   TP  P+P  
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 414

Query: 512 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 548
           P  P  +   +   +   T EPA  +P  P PTA ++
Sbjct: 415 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 448



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +        P++T P    EP P              T   +PA  +P  P
Sbjct: 764 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 809

Query: 542 PPTAAE 547
           PPT +E
Sbjct: 810 PPTTSE 815



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 17/66 (25%), Positives = 27/66 (40%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +P       P++       EP P  + S  +     +  TT+ A  +P  P
Sbjct: 296 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 355

Query: 542 PPTAAE 547
            PT  +
Sbjct: 356 APTTTK 361



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 538
           T T+ P   SP    +  P  T  AP+    P P  + S+ +     S T T EPA  +P
Sbjct: 468 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524

Query: 539 GRPPPTAAER 548
             P PT  ++
Sbjct: 525 KEPAPTTPKK 534



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)

Query: 480 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 539
           S T T+ P   +P    + P   TP  P+P  P  P  +   +   + T T +PA  +P 
Sbjct: 512 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 565

Query: 540 RPPPT 544
            P PT
Sbjct: 566 EPAPT 570



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 499 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 544
           P     PAP+ P+ P P  L+ ++  G +ST + +PA  +P    PT
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 114/513 (22%), Positives = 176/513 (34%), Gaps = 75/513 (14%)

Query: 830  SPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEP 887
            +P   +P     +P +P  P P + K +   P E      P P       P    E    
Sbjct: 362  TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPT 415

Query: 888  VSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPT 947
             +    P+   + P +P++ P   + +   P+TP   + P   KE T       PT+   
Sbjct: 416  TTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPA-PTTPKEPT-------PTT--- 463

Query: 948  QRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD 1007
                      P   A T K P   +   P P AP   +PT P       P+E +P    +
Sbjct: 464  ----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 513

Query: 1008 GA--SPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPV-PSQMPWLVASPEPPQSSPT 1064
             +  +P+ P PTT    + AP       P +   +P TP  PS       +P  P+  P 
Sbjct: 514  PSPTTPKEPAPTTT---KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE-PA 569

Query: 1065 PAFPLAASYDTNGLSQPPLPE-------KRHLPGPGQQPGPWGPEQASSPARGISHHVTF 1117
            P  P   +  T     P  P+       K+  P   ++P P  P++ ++P        T 
Sbjct: 570  PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE-TAPTTPKKLTPTT 628

Query: 1118 APLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDS 1177
               L+   P+ P P T E  +     + T     +P  +  +A A    K+P        
Sbjct: 629  PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 682

Query: 1178 HSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKI----KGCPSEPYFG 1233
                       K   P    +P    P E         T PKG       +  P+ P   
Sbjct: 683  --------TTPKEPAPTTPKEPAPTTPKETA------PTTPKGTAPTTLKEPAPTTPKKP 728

Query: 1234 SLSALVSQHSISPISLPCCLRIPS--KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYL 1291
            +   L    +  P S  C    P+  K     TP+ P PT     A    +G A + L  
Sbjct: 729  APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788

Query: 1292 TSVETESLTGPQAVA----RASSAALSCSPRPT 1320
             +  T     P+ +A    +  ++  S  P PT
Sbjct: 789  PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 105/476 (22%), Positives = 163/476 (34%), Gaps = 61/476 (12%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD--RYPLPGHLASAGPLASAESLEPV 888
            P   +P+  + +    P P + K +   P E      + P P       P    E     
Sbjct: 404  PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463

Query: 889  SWREGPSGHSTLPRSPRDA-------PCSASSELSGPSTPLHTSSPVQGKESTRRQDTRS 941
                 P+     P +P++        P   + +   P+TP   +     + S       +
Sbjct: 464  PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523

Query: 942  PTSAPTQRLSPGEALPPVSQAG--TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 999
            PT+  +   +  E  P  +++   T K P   +   P P  P   +PT P       P+E
Sbjct: 524  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583

Query: 1000 RSPGGHSDGA----------SPRSPVPTTLPGLRHAPWQGPRGPPDSPDG----SPLTPV 1045
             +P    + A          +P+ P PTT      AP    +  P +P+     +P  P 
Sbjct: 584  PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK--ETAPTTPKKLTPTTPEKLAPTTPEKPA 641

Query: 1046 PSQMPWLV-ASPEPPQSS----PTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1100
            P+    L   +PE P  +    P P  P AA+ +T     P  P K   P   ++P P  
Sbjct: 642  PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP-KEPAPTTPKEPAPTT 700

Query: 1101 P-EQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQ 1159
            P E A +  +G     T    L +  P TP+ P  +  +     + TS    KP  +  +
Sbjct: 701  PKETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755

Query: 1160 AIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPK 1219
              A    K+P     ++        G A      P    P K  P E      L  T  K
Sbjct: 756  GTAPTTPKEPAPTTPKEPAPTTPK-GTAPTTLKEPAPTTPKKPAPKE------LAPTTTK 808

Query: 1220 G----VKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPT 1271
            G       K  P+ P     +A  +    +P +         K P   TPE P PT
Sbjct: 809  GPTSTTSDKPAPTTP---KETAPTTPKEPAPTT--------PKKPAPTTPETPPPT 853



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 36/349 (10%)

Query: 829  PSPGAHSPRAGSISPGSP-----PYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAE 883
            PSP      A + +  +P     P P + K +   P E      P P       P    E
Sbjct: 514  PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE------PSPTTTKEPAPTTPKE 567

Query: 884  SLEPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 942
                   +  P+      P +P++ P   +++   P+TP   + P   KE+      +  
Sbjct: 568  PAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLT 625

Query: 943  TSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSP 1002
             + P ++L+P     P        AP  P    P P  P   +PT P ++  + P+E +P
Sbjct: 626  PTTP-EKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTPEEPAPTTPKAAAPNTPKEPAP 682

Query: 1003 GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSS 1062
                   +P+ P PTT      AP       P +P G+  T +    P     P P + +
Sbjct: 683  ------TTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734

Query: 1063 PTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP-EQASSPARGISHHVTFAPL 1120
            PT    P + + D       P   K   P   ++P P  P E A +  +G     T    
Sbjct: 735  PTTTKEPTSTTCD----KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-----TAPTT 785

Query: 1121 LSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDP 1169
            L +  P TP+ P  +  +       TS    KP  +  +  A    K+P
Sbjct: 786  LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 103/487 (21%), Positives = 168/487 (34%), Gaps = 57/487 (11%)

Query: 851  SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS 910
            S K +  I      D  P    LA   P A   +  P       +     P +P++ P S
Sbjct: 306  SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL----TTPKEPTPTTPKE-PAS 360

Query: 911  ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS----APTQRLSPGEALPPVSQAGTGK 966
             + +   P+T    S+P   KE        +PT+    APT    P    P      T K
Sbjct: 361  TTPKEPTPTTI--KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 418

Query: 967  --APELPSGSGPEPLAPSPVSPTFP-PSSPSD----WPQERSPGGHSDGASPRSPVPTTL 1019
              AP     +   P  P+P +P  P P++P +     P+E +P       +P+ P PTT 
Sbjct: 419  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP------TTPKEPAPTTK 472

Query: 1020 PGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLS 1079
                      P  P +    +P  P P+         EP  ++P    P      +    
Sbjct: 473  E-------PAPTTPKEPAPTAPKKPAPT------TPKEPAPTTPKEPAPTTTKEPSPTTP 519

Query: 1080 QPPLP-EKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS 1138
            + P P   +  P   ++P P   + A +  +  S   T  P  +   P+ P P T +  +
Sbjct: 520  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP--APTTPKEPAPTTPKKPA 577

Query: 1139 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA-TPPPSA 1197
                 +       +P  +  +  A    K+P     +++     A     K+  T P   
Sbjct: 578  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET-----APTTPKKLTPTTPEKL 632

Query: 1198 QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPS 1257
             P   +         L  T P+       P EP      A  +  + +P +         
Sbjct: 633  APTTPEKPAPTTPEELAPTTPE-EPTPTTPEEP------APTTPKAAAPNTPKEPAPTTP 685

Query: 1258 KDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASS---AALS 1314
            K+P   TP+ P PT     A    +G A + L   +  T     P+ +A  ++    + +
Sbjct: 686  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745

Query: 1315 C-SPRPT 1320
            C  P PT
Sbjct: 746  CDKPAPT 752



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 76/342 (22%), Positives = 117/342 (34%), Gaps = 57/342 (16%)

Query: 831  PGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSW 890
            P   +P+A +  P +P  P         PT         P   A   P  +A    P + 
Sbjct: 664  PAPTTPKAAA--PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA----PTTL 717

Query: 891  REGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRL 950
            +E      T P+ P      A  EL+  +T   TS+       T  + T   T       
Sbjct: 718  KEPAP---TTPKKP------APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 768

Query: 951  SPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF---PPSSPSDWPQERSPGGHSD 1007
            +P E  P   +       + P+ + P+  AP  ++PT    P S+ SD P   +P   + 
Sbjct: 769  TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-KETA 827

Query: 1008 GASPRSPVPTTLPGLRHAPWQGPRGP-PDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPA 1066
              +P+ P PTT           P+ P P +P+  P T      P     P     SP  +
Sbjct: 828  PTTPKEPAPTT-----------PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 876

Query: 1067 FPLAASYDT-----NGLSQPPLPEKRHLPGPGQQPGPWGPEQASS--------PARGISH 1113
             P  ++  T     N   +P +P  +        P    PE  ++          R    
Sbjct: 877  TPELSAEPTPKALENSPKEPGVPTTK-------TPAATKPEMTTTAKDKTTERDLRTTPE 929

Query: 1114 HVTFAPLLSDNVPQTPEPPTQE------SQSNVKFVQDTSKF 1149
              T AP ++     T E  T+       +Q      QDT+ F
Sbjct: 930  TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 971



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 67/368 (18%), Positives = 116/368 (31%), Gaps = 52/368 (14%)

Query: 809  CPAYGRV---PHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGD 865
            CP Y       H+  SP   +  P P   S    S +  SP  P  +K    I +EE  +
Sbjct: 97   CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE 156

Query: 866  RYPLPGHLASAGPLASAES---LEPVSWREGPSGHSTLPRS--PRDAPCSASSELSGPST 920
             + +  +  S+   +S+ S   +  +   +  + +  L +    +D   + + +   P  
Sbjct: 157  EHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 216

Query: 921  PL------------------HTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQA 962
            P+                   TS+    K ST      SP     + ++P  +LPP S  
Sbjct: 217  PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVST------SPKITTAKPINPRPSLPPNSDT 270

Query: 963  G-----------------TGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGH 1005
                              T    +  S  G E    +  + +   +S  D          
Sbjct: 271  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330

Query: 1006 SDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTP 1065
                +P++   T  P L       P  P +    +P  P P+ +     +P+ P  + T 
Sbjct: 331  P---TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387

Query: 1066 AFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNV 1125
            + P          ++ P P     P P     P      S+P        T     +   
Sbjct: 388  SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447

Query: 1126 PQTPEPPT 1133
            P+ P P T
Sbjct: 448  PKEPAPTT 455



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 13/157 (8%)

Query: 400 TIHGPQLTFPKDQL-----DEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVD- 453
           T  GP LT PK+       + A T  + P   +++    ++P++   +T ++ P+   + 
Sbjct: 338 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKSAPTTPKEP 396

Query: 454 --YNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEP 511
               T EPA             E +   + +    P + +P    ++P   TP  P+P  
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT 455

Query: 512 PPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAER 548
           P  P  +   +   +   T EPA  +P  P PTA ++
Sbjct: 456 PKEPTPTTPKEPAPT---TKEPAPTTPKEPAPTAPKK 489



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 14/66 (21%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +        P++T P    EP P              T   +PA  +P  P
Sbjct: 805 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--------------TTPKKPAPTTPETP 850

Query: 542 PPTAAE 547
           PPT +E
Sbjct: 851 PPTTSE 856



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 17/66 (25%), Positives = 27/66 (40%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP 541
           T T+GP   +P       P++       EP P  + S  +     +  TT+ A  +P  P
Sbjct: 337 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 396

Query: 542 PPTAAE 547
            PT  +
Sbjct: 397 APTTTK 402



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 482 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGH---SSTLTTEPAAESP 538
           T T+ P   SP    +  P  T  AP+    P P  + S+ +     S T T EPA  +P
Sbjct: 509 TTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565

Query: 539 GRPPPTAAER 548
             P PT  ++
Sbjct: 566 KEPAPTTPKK 575



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 6/65 (9%)

Query: 480 SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG 539
           S T T+ P   +P    + P   TP  P+P  P  P  +   +   + T T +PA  +P 
Sbjct: 553 SPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPK 606

Query: 540 RPPPT 544
            P PT
Sbjct: 607 EPAPT 611



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 499 PPRQTPPAPS-PEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPT 544
           P     PAP+ P+ P P  L+ ++  G +ST + +PA  +P    PT
Sbjct: 783 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 97/349 (27%), Positives = 118/349 (33%), Gaps = 45/349 (12%)

Query: 794  PALVTYSYGGAVPSYCPAYGRVPHSCGSP-GEGRGYPSPGAHSPRAGSISPGSP--PYPQ 850
            P+L+  +  GA P      G  P    SP G+ +G P  G + P+     PG P  P PQ
Sbjct: 29   PSLIAGNPQGAPPQG----GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 84

Query: 851  SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLE--PVSWREGPSGHSTLPRSPRDAP 908
                  + P   G  + P P    S  P +     +  P      P G    P  P+  P
Sbjct: 85   GGN-KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 143

Query: 909  CSASSELSGPSTP-LHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKA 967
                ++  GP  P      P QG   +R   +RSP   P          PP       + 
Sbjct: 144  PQGGNKPQGPPPPGKPQGPPPQGDNKSR--SSRSPPGKPQG--------PPPQGGNQPQG 193

Query: 968  PELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSP--VPTTLPGLRHA 1025
            P  P G    P       P  PP  P   PQ   P G +   S RSP   P   P     
Sbjct: 194  PPPPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251

Query: 1026 PWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPE 1085
              QGP  PP  P G P  P     P     P  PQ  P    P   S   +  S P  P+
Sbjct: 252  QPQGPPPPPGKPQGPP--PQGGNKPQGPPPPGKPQGPP----PQGGSKSRSSRSPPGKPQ 305

Query: 1086 KRHLPGPGQQPG--PWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPP 1132
                 GP  Q G  P GP       +G        P    N PQ P PP
Sbjct: 306  -----GPPPQGGNQPQGPPPPPGKPQG-------PPPQGGNKPQGPPPP 342



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 91/343 (26%), Positives = 115/343 (33%), Gaps = 36/343 (10%)

Query: 810  PAYGRVPHSCGSPGEGRGYPSPG--AHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRY 867
            P  G  P     PG+ +G P  G  + SPR+    P  PP PQ        P   G  + 
Sbjct: 83   PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQG 141

Query: 868  PLP-GHLASAGPLASAESLEPVSWREGPSGHS-TLPRSPRDAPCSASSELSGPSTPLHTS 925
            P P G     GP    +   P    +  S  S + P  P+  P    ++  GP  P    
Sbjct: 142  PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201

Query: 926  S---PVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPS 982
                P  G +         P   P Q  +  ++    S  G  + P    G+ P+   P 
Sbjct: 202  QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR--SPPGKPQGPPPQGGNQPQGPPPP 259

Query: 983  PVSPTFPPSSPSDWPQERSPGGHSDGASP----RSPVPTTLPGLRHAP-------WQGPR 1031
            P  P  PP    + PQ   P G   G  P    +S    + PG    P        QGP 
Sbjct: 260  PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319

Query: 1032 GPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPG 1091
             PP  P G P  P     P     P  PQ  P    P   S   +  S P  P+     G
Sbjct: 320  PPPGKPQGPP--PQGGNKPQGPPPPGKPQGPP----PQGGSKSRSARSPPGKPQ-----G 368

Query: 1092 PGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQ 1134
            P QQ G   P+    PA G        P      PQ P  P Q
Sbjct: 369  PPQQEGN-NPQGPPPPAGGNPQQPQAPPA---GQPQGPPRPPQ 407



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 82/308 (26%), Positives = 107/308 (34%), Gaps = 29/308 (9%)

Query: 822  PGEGRGYPSPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPG----HLAS 875
            PG+ +G P  G + P+     PG P  P PQ      + P   G  + P P       +S
Sbjct: 115  PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP-QGPPPPGKPQGPPPQGDNKSRSS 173

Query: 876  AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTR 935
              P    +   P    + P G    P  P+  P    ++  GP  P     P    ++ +
Sbjct: 174  RSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN-K 231

Query: 936  RQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTF--PPSSP 993
             Q  RSP   P      G   P       GK    P   G +P  P P       PP   
Sbjct: 232  SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291

Query: 994  SDWPQERSPGGHSDGASPRS-------PVPTTLPGLRHAPWQG---PRGPPDSPDGSPLT 1043
            S     RSP G   G  P+        P P   P  +  P QG   P+GPP  P G P  
Sbjct: 292  SKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPP--PPGKPQG 347

Query: 1044 PVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPP--LPEKRHLPGPGQQPGPWGP 1101
            P P       ++  PP     P  P     +  G   P    P++   P  GQ  GP  P
Sbjct: 348  PPPQGGSKSRSARSPPGKPQGP--PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405

Query: 1102 EQASSPAR 1109
             Q   P+R
Sbjct: 406  PQGGRPSR 413



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 79/277 (28%), Positives = 100/277 (36%), Gaps = 43/277 (15%)

Query: 879  LASAESL-EPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTP--LHTSSPVQGKESTR 935
            L+SA++L E VS  E PS    +  +P+ AP    ++  GP +P       P QG    +
Sbjct: 13   LSSAQNLNEDVSQEESPS---LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQ 69

Query: 936  RQDTR--SPTSAPTQRLS-------PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSP 986
                    P   P Q  +       PG+   P  Q    ++P  P G    P       P
Sbjct: 70   GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 129

Query: 987  TFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP------RGPPDSPDGS 1040
              PP  P   PQ   P G   G  P+ P P   P  +  P QG       R PP  P G 
Sbjct: 130  QGPPPPPGK-PQGPPPQG---GNKPQGPPPPGKP--QGPPPQGDNKSRSSRSPPGKPQGP 183

Query: 1041 PLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWG 1100
            P  P     P     P PP   P    P        G ++P  P     PG  Q P P G
Sbjct: 184  P--PQGGNQP---QGPPPPPGKPQGPPP-------QGGNKPQGPPP---PGKPQGPPPQG 228

Query: 1101 PEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQ 1137
              ++ S AR         P    N PQ P PP  + Q
Sbjct: 229  DNKSQS-ARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 264



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 50/189 (26%), Positives = 67/189 (35%), Gaps = 20/189 (10%)

Query: 822  PGEGRGYPSPGAHSPRAGSISPGSP--PYPQSRKLSYEIPTEEGGDRYPLPG----HLAS 875
            PG+ +G P  G + P+     PG P  P PQ      + P   G  + P P       +S
Sbjct: 239  PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP-QGPPPPGKPQGPPPQGGSKSRSS 297

Query: 876  AGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPV-QGKEST 934
              P    +   P    + P G    P  P+  P    ++  GP  P     P  QG   +
Sbjct: 298  RSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356

Query: 935  RRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE-PLAPSPVSPTFPPSSP 993
            R    RSP   P          PP  +    + P  P+G  P+ P AP    P  PP  P
Sbjct: 357  R--SARSPPGKPQG--------PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 406

Query: 994  SDWPQERSP 1002
                  R P
Sbjct: 407  QGGRPSRPP 415



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 36/144 (25%), Positives = 48/144 (33%), Gaps = 11/144 (7%)

Query: 491 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE 550
           SP  + Q PP Q    P   PPPP         G +      P  +  G PPP    +  
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG-PPPQGDNKSR 171

Query: 551 LDRLLGGCGVA----SGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRP------GLSR 600
             R   G         G +  G        +  P  GG    G  P  +P      G ++
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231

Query: 601 HCSCRQGYREPCGVPNGGYYRPEG 624
             S R    +P G P  G  +P+G
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQG 255



 Score = 31.2 bits (69), Expect = 7.4
 Identities = 35/143 (24%), Positives = 47/143 (32%), Gaps = 9/143 (6%)

Query: 491 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE 550
           SP  + Q PP Q    P   PPPP         G +      P  +  G PP   ++ + 
Sbjct: 237 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296

Query: 551 LDRLLG---GCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRP------GLSRH 601
                G   G     G +  G        +  P  GG    G  P  +P      G S+ 
Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356

Query: 602 CSCRQGYREPCGVPNGGYYRPEG 624
            S R    +P G P      P+G
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQG 379


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 188/771 (24%), Positives = 249/771 (32%), Gaps = 135/771 (17%)

Query: 511  PPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELD------------RLLGGC 558
            P PP  L +   SG       +     PG P PT  +  + +             LLG  
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 559  GVAS--------GGRGAGRETAILDDEEQPTVGGGPHLGVYPGHR--PGLSRHCSCRQGY 608
            G           G  G      +  D  QP + G P L   PG +  PGL      + G 
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG----QPGL 1019

Query: 609  REPCG----VPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSE-GLYP 663
              P G    + + G+  P+G          G  G P        +  +    +S  GL  
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGV--EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1077

Query: 664  YPPEMGKPATGDFGYRA-PGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLERE 722
             P   G+P  G  GY   PG +  V   DPGLP L   P  + +  LP            
Sbjct: 1078 LPGPKGEP--GLPGYPGNPGIKGSV--GDPGLPGLPGTPGAKGQPGLPG-------FPGT 1126

Query: 723  AGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTM 782
             G         P  +P  PG P P+     GH   P P          GE+G  G     
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPV--GGGGHPGQPGPP---------GEKGKPGQDGIP 1175

Query: 783  CPEGRYGHPGYPALVTYSYGGAVPSYCPAY------GRVPHSCGSPGEGRGYPSPGAHSP 836
             P G+ G PG P      +G   P   P        G +P   G+PG       PG H  
Sbjct: 1176 GPAGQKGEPGQP-----GFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF 1230

Query: 837  RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSG 896
                  PG P  P         P  EG    P P      GP            R GP+G
Sbjct: 1231 PGVQGPPGPPGSPG--------PALEGPKGNPGP-----QGP----------PGRPGPTG 1267

Query: 897  HSTL--PRSPRDAPCSA--SSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSP 952
               L  P  P   P +     E   P  P     P    +        +P       +  
Sbjct: 1268 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1327

Query: 953  GEALPPVSQAGTGKAPE-LPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP 1011
               LP V      K P  +P  +GPE   P  + P  PP  P   P  +S     D   P
Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPGSAGPEG-EPGLIGPPGPPGLPG--PSGQSIIIKGDAGPP 1384

Query: 1012 RSPVPTTLPGLRHAPW-QGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLA 1070
              P     PGL+  P  QGP+G P  P G P  P  + +P    +         P  P  
Sbjct: 1385 GIP---GQPGLKGLPGPQGPQGLP-GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP-- 1438

Query: 1071 ASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARG--ISHHVTFAPLLSDNVPQT 1128
                T GL  P        PGP    GP GP   SS A G  I+ H       + + PQ 
Sbjct: 1439 ---GTRGLDGP--------PGPDGLQGPPGPPGTSSVAHGFLITRHSQ-----TTDAPQC 1482

Query: 1129 PEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFL-IRDSHSFQGAYGLA 1187
            P+   Q  +         +K  +   L    +        P  F  I +  +F      +
Sbjct: 1483 PQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYS 1542

Query: 1188 LKVATPPP---SAQPWKGDPVEQLVRHFLIETGP--------KGVKIKGCP 1227
              ++TP P   S QP KG  ++  +    +   P        + ++I  CP
Sbjct: 1543 YWLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCP 1593



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 93/346 (26%), Positives = 109/346 (31%), Gaps = 64/346 (18%)

Query: 767  PPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGR--------VPHS 818
            P   G +G  G        G  G+PG P L     G   P   P +G         +   
Sbjct: 584  PGLPGPKGEPGGITFKGERGPPGNPGLPGLP----GNIGPMGPPGFGPPGPVGEKGIQGV 639

Query: 819  CGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQS--RKLSYEIPTEEGGDRYPLPGHLASA 876
             G+PG+  G P P    P      PG P  P +  R     +P + G     LPG     
Sbjct: 640  AGNPGQP-GIPGPKG-DPGQTITQPGKPGLPGNPGRDGDVGLPGDPG-----LPGQPGLP 692

Query: 877  G-PLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTR 935
            G P +  E   P     GP G    P  P   P  A      P TP              
Sbjct: 693  GIPGSKGEPGIPGIGLPGPPGPKGFPGIP--GPPGA------PGTPGRIGL--------- 735

Query: 936  RQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSD 995
             +    P   P  +  PG ALP     G    P      GP+     P     PP  P  
Sbjct: 736  -EGPPGPPGFPGPKGEPGFALP--GPPGPPGLPGFKGALGPKGDRGFPG----PPGPPGR 788

Query: 996  WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS 1055
               +  PG   D      P P   PGL     QGP GPP  P G    P    +P     
Sbjct: 789  TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP-GPIGQPGLHGIPGEKGD 847

Query: 1056 PEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGP 1101
            P PP                 GL  P  P +R  PG    PGP GP
Sbjct: 848  PGPP-----------------GLDVPGPPGERGSPGIPGAPGPIGP 876



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 116/448 (25%), Positives = 145/448 (32%), Gaps = 104/448 (23%)

Query: 725  EGWASEAGKPLL--HPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTM 782
            +G   E G P L  HP  PG P P           P        P   G++G +G     
Sbjct: 44   KGEKGERGFPGLEGHPGLPGFPGP---------EGP--------PGPRGQKGDDGIPGPP 86

Query: 783  CPEGRYGHPGYPALVTYSYGGAVPSY--CPAYGRVPHSCGSPGEGRGYPS----PGAHSP 836
             P+G  G PG P          +P +   P    +P   G+ GE RG+P     PG   P
Sbjct: 87   GPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE-RGFPGSPGFPGLQGP 145

Query: 837  RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYP-LPGHLASAGPLASAESLEPVS--WREG 893
                  PG    P S  +S  +P  +G   YP  PG     GP      + P       G
Sbjct: 146  PGPPGIPGMKGEPGSIIMS-SLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204

Query: 894  PSGHSTLPRSPR-------DAPCSASSE--LSGPSTPLHTSSPVQGKESTRRQDT----- 939
            P G   LP  P+         P     E  L GP  P     P Q  E  R  D      
Sbjct: 205  PPGPPGLP-GPKGNMGLNFQGPKGEKGEQGLQGPPGP-----PGQISEQKRPIDVEFQKG 258

Query: 940  -------RSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFP--P 990
                   R P   P  R  PG       + G    P      G +     P  P  P  P
Sbjct: 259  DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318

Query: 991  SSPSDWPQERSPGGHSDGASPRSP---VPTT-------------LPGL------RHAPW- 1027
              P +  ++   G   D   P  P   +P               LPGL      R  P  
Sbjct: 319  GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI 378

Query: 1028 QGPRGPPDSPDGSPLTP-----VPSQM-------PWLVASPEPPQSSPTPAFPLAASYDT 1075
            QGP G P  P  + + P      P +        P  ++ P PP     P  P       
Sbjct: 379  QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP------- 431

Query: 1076 NGLSQPPLPEKRHLPGPGQ--QPGPWGP 1101
             GL  PP P   H+P   +  +PGP GP
Sbjct: 432  -GLPGPPGPAGPHIPPSDEICEPGPPGP 458



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 101/383 (26%), Positives = 131/383 (34%), Gaps = 70/383 (18%)

Query: 767  PPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGR 826
            P + G +G +G       +G  G PG P LV    G  +         +P   G  GE R
Sbjct: 321  PGEPGRDGEKG------QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE-R 373

Query: 827  GYPS----PGAHSPRAGSIS--PGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLA 880
            G+P     PG   P   ++   PG P +P  R         + GD  P PG      P  
Sbjct: 374  GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG--------QKGDEGP-PGISIPGPPGL 424

Query: 881  SAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSP----VQGKESTR- 935
              +   P     GP G    P  P   P   S E+  P  P    SP    +QG++  + 
Sbjct: 425  DGQPGAP--GLPGPPG----PAGPHIPP---SDEICEPGPPGPPGSPGDKGLQGEQGVKG 475

Query: 936  -RQDT------RSPTSAPTQRLSPGEALPPVSQAGTGKAPEL--PSGSGPEPLAP---SP 983
             + DT         +  P Q   PG   PP S    G+  E      +GP+ L     +P
Sbjct: 476  DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAP 535

Query: 984  VSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQ-------GPRGPP-- 1034
             +P FP S          PG   D     SP    LPGL   P Q       GP+G P  
Sbjct: 536  GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 1035 ---DSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPG 1091
                   G P  P    +P  +    PP   P    P+           P  P    +PG
Sbjct: 596  ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGVAGNPGQP---GIPG 650

Query: 1092 PGQQPG-----PWGPEQASSPAR 1109
            P   PG     P  P    +P R
Sbjct: 651  PKGDPGQTITQPGKPGLPGNPGR 673



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 175/690 (25%), Positives = 223/690 (32%), Gaps = 133/690 (19%)

Query: 485  RGP--LDGSPYAQVQRPPRQTPPAPSPE-----PPPPPMLSVSSDSGHSSTLTTEPAAES 537
            +GP  L G P A V  PP   PP    E        PP +S+    G    L  +P A  
Sbjct: 379  QGPPGLPGPPGAAVMGPPG--PPGFPGERGQKGDEGPPGISIPGPPG----LDGQPGAPG 432

Query: 538  -PGRPPPTAAERQELDRLLG----GCGVASGGRGAGRETAILDDEEQPTVGG-GPHLGVY 591
             PG P P        D +      G   + G +G   E  +  D+        G  +   
Sbjct: 433  LPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGP 492

Query: 592  PGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKR 651
            PG +PGL              G+P      P G+L      + G +G  +G A A+  K 
Sbjct: 493  PG-QPGLP-------------GLPG-----PPGSL-----GFPGQKGE-KGQAGATGPKG 527

Query: 652  RLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYR-EVVILEDPGLPALYPCPACEEKLALP 710
                  + G   +P   G+P  GD     PG + +   L  PG P L   P    +  LP
Sbjct: 528  LPGIPGAPGAPGFPGSKGEP--GDI-LTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584

Query: 711  TAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKA 770
               L G + E   G  +  E G P       G+P    LP    +  PM       P   
Sbjct: 585  --GLPGPKGE-PGGITFKGERGPP-------GNPG---LPGLPGNIGPMGPPGFGPPGPV 631

Query: 771  GEEGHEGCS----------------YTMCPEGRYGHPGYPAL---VTYSYGGAVPSYCPA 811
            GE+G +G +                 T+   G+ G PG P     V       +P   P 
Sbjct: 632  GEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ-PG 690

Query: 812  YGRVPHSCGSPG-EGRGYPSP-------GAHSPRAGSISPG-----SPPYPQSRKLSYEI 858
               +P S G PG  G G P P       G   P     +PG      PP P         
Sbjct: 691  LPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG------F 744

Query: 859  PTEEGGDRYPLPGHLASAGPLASAESLEPVSWR-----EGPSGHSTLPRSPRDAPCSASS 913
            P  +G   + LPG     G      +L P   R      GP G + L   P        +
Sbjct: 745  PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 914  ELSGPSTPLHTSS-PVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPS 972
               GP  P       VQG           P   P     PGE   P         P    
Sbjct: 805  GQPGPMGPPGLPGIGVQGPPGP--PGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862

Query: 973  GSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSD---GASPRSPVPTTLPGLRHAPW-- 1027
            GS   P AP P+ P   P  P        PG   +      P  P P  +PG    P   
Sbjct: 863  GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLK 922

Query: 1028 --QGPRGPPDSP--------DGSPLTPVP--SQMPWLVASPEPPQSSPTPAFP-LAASYD 1074
               G +G P  P         G P  P P     P L+ S         P  P ++    
Sbjct: 923  GDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG 982

Query: 1075 TNGL----SQPPLPEKRHLPGPGQQPGPWG 1100
              GL     QP L  +  LPGP   PGP G
Sbjct: 983  YQGLPGDPGQPGLSGQPGLPGP---PGPKG 1009



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 84/335 (25%), Positives = 103/335 (30%), Gaps = 82/335 (24%)

Query: 792  GYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQS 851
            G PA     YG +  S C   G      G  GE RG+P    H    G   P  PP P+ 
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIK----GEKGE-RGFPGLEGHPGLPGFPGPEGPPGPRG 75

Query: 852  RKLSYEIPTEEG--GDRYP--------------LPGHLASAGPLASAESLEPVSWREGPS 895
            +K    IP   G  G R P              +PGH  + GP       + +    G  
Sbjct: 76   QKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP-------QGIPGCNGTK 128

Query: 896  GHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEA 955
            G    P SP          L GP  P      + G +        S  S P  + +PG  
Sbjct: 129  GERGFPGSP------GFPGLQGPPGP----PGIPGMKGEPGSIIMS--SLPGPKGNPGYP 176

Query: 956  LPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPV 1015
             PP  Q        LP  +G     P P+ P  P            PG       P  P 
Sbjct: 177  GPPGIQG-------LPGPTG----IPGPIGPPGP------------PGLMGPPGPPGLPG 213

Query: 1016 PTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDT 1075
            P    GL    +QGP+G                   L   P PP        P+   +  
Sbjct: 214  PKGNMGLN---FQGPKGEKGEQG-------------LQGPPGPPGQISEQKRPIDVEFQK 257

Query: 1076 NGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARG 1110
                   LP  R  PGP    GP GP       +G
Sbjct: 258  ---GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,823,129
Number of Sequences: 37866
Number of extensions: 5150682
Number of successful extensions: 45146
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 359
Number of HSP's successfully gapped in prelim test: 2110
Number of HSP's that attempted gapping in prelim test: 21640
Number of HSP's gapped (non-prelim): 17618
length of query: 1419
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1304
effective length of database: 13,892,928
effective search space: 18116378112
effective search space used: 18116378112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.