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Search of human proteins with 38683860
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38683860 insulin receptor substrate 2 [Homo sapiens]
(1338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 2742 0.0
gi|5031805 insulin receptor substrate 1 [Homo sapiens] 650 0.0
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 298 3e-80
gi|163965366 nascent polypeptide-associated complex alpha subuni... 100 9e-21
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 85 5e-16
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 83 2e-15
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 82 3e-15
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 5e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 80 1e-14
gi|153792074 proline rich 12 [Homo sapiens] 80 2e-14
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 79 2e-14
gi|55750053 atrophin-1 [Homo sapiens] 79 3e-14
gi|55750041 atrophin-1 [Homo sapiens] 79 3e-14
gi|112421108 capicua homolog [Homo sapiens] 78 5e-14
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 77 1e-13
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 77 1e-13
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 76 2e-13
gi|110832843 TBP-associated factor 4 [Homo sapiens] 75 3e-13
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 74 1e-12
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 73 2e-12
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 72 4e-12
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 71 6e-12
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 71 6e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 71 6e-12
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 70 1e-11
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 2e-11
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 2e-11
gi|113430177 PREDICTED: hypothetical protein [Homo sapiens] 70 2e-11
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 70 2e-11
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 69 2e-11
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 2742 bits (7108), Expect = 0.0
Identities = 1338/1338 (100%), Positives = 1338/1338 (100%)
Query: 1 MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA 60
MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA
Sbjct: 1 MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA 60
Query: 61 TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE 120
TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE
Sbjct: 61 TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE 120
Query: 121 YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPAAAPAASCSASLPGALGGSAGAAGA 180
YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPAAAPAASCSASLPGALGGSAGAAGA
Sbjct: 121 YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPAAAPAASCSASLPGALGGSAGAAGA 180
Query: 181 EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL 240
EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL
Sbjct: 181 EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL 240
Query: 241 QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF 300
QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF
Sbjct: 241 QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF 300
Query: 301 RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR 360
RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR
Sbjct: 301 RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR 360
Query: 361 VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP 420
VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP
Sbjct: 361 VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP 420
Query: 421 AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR 480
AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR
Sbjct: 421 AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR 480
Query: 481 PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY 540
PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY
Sbjct: 481 PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY 540
Query: 541 GYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL 600
GYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL
Sbjct: 541 GYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL 600
Query: 601 MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA 660
MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA
Sbjct: 601 MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA 660
Query: 661 ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTF 720
ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTF
Sbjct: 661 ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTF 720
Query: 721 PASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTP 780
PASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTP
Sbjct: 721 PASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTP 780
Query: 781 PDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLE 840
PDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLE
Sbjct: 781 PDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLE 840
Query: 841 PQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPS 900
PQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPS
Sbjct: 841 PQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPS 900
Query: 901 LPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGS 960
LPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGS
Sbjct: 901 LPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGS 960
Query: 961 GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPR 1020
GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPR
Sbjct: 961 GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPR 1020
Query: 1021 PSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVA 1080
PSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVA
Sbjct: 1021 PSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVA 1080
Query: 1081 ATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADP 1140
ATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADP
Sbjct: 1081 ATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADP 1140
Query: 1141 QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEP 1200
QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEP
Sbjct: 1141 QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEP 1200
Query: 1201 PTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVRE 1260
PTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVRE
Sbjct: 1201 PTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVRE 1260
Query: 1261 EPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTY 1320
EPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTY
Sbjct: 1261 EPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTY 1320
Query: 1321 ASIDFLSHHLKEATIVKE 1338
ASIDFLSHHLKEATIVKE
Sbjct: 1321 ASIDFLSHHLKEATIVKE 1338
>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
Length = 1242
Score = 650 bits (1677), Expect = 0.0
Identities = 534/1384 (38%), Positives = 669/1384 (48%), Gaps = 301/1384 (21%)
Query: 31 VRKCGYLRKQKHGHKRFFVLRGPGAGGDEATAGGGSAPQPPRLEYYESEKKWRSKAGAPK 90
VRK GYLRK K HKRFFVLR A+ GG P RLEYYE+EKKWR K+ APK
Sbjct: 13 VRKVGYLRKPKSMHKRFFVLRA-------ASEAGG----PARLEYYENEKKWRHKSSAPK 61
Query: 91 RVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRAAA 150
R I L+ C NINKRAD+K+K+L+ALYT+DE+FA+AA++E EQ+ WY+AL L RA
Sbjct: 62 RSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQL--HNRAKG 119
Query: 151 GDAPPAAAPAASCSASLPGALGGSAGAAGAEDSYGLVAPATAAYREVWQVNLKPKGLGQS 210
AA A S G+ G G AG + SYG V P A ++EVWQV LKPKGLGQ+
Sbjct: 120 HHDGAAALGAGGGGGSCSGSSG--LGEAGEDLSYGDVPPGPA-FKEVWQVILKPKGLGQT 176
Query: 211 KNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGEL 270
KNL G+YRLCL+++TI FVKLN E +V LQLMNIRRCGHS++FFFIEVGRSAVTGPGE
Sbjct: 177 KNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEF 236
Query: 271 WMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVN 330
WMQ DDSVVAQN+HETILEAM+A+ + EFRPRSKSQSS S+ ++PISVP R HHL N
Sbjct: 237 WMQVDDSVVAQNMHETILEAMRAMSD--EFRPRSKSQSS-SNCSNPISVP--LRRHHLNN 291
Query: 331 LPPSQTGLVRRSRTDSLAATPPAA----KCSSCRVRTASEGDGGAAAGAAAAGARPVSVA 386
PPSQ GL RRSRT+S+ AT PA+ K S RVR +S+G+G +RP SV
Sbjct: 292 PPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEG--------TMSRPASVD 343
Query: 387 GSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPG 446
GSP+SP R R RGS P L HSRS+ MP + P+ATSP
Sbjct: 344 GSPVSPSTNRTHAHRH---------RGSARLHPP----LNHSRSIPMPASRCSPSATSPV 390
Query: 447 SLSSS--SGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYG 504
SLSSS SGHGS S P SAS SGSPSD GF+S DEYG
Sbjct: 391 SLSSSSTSGHGSTS------------------DCLFPRRSSASVSGSPSDGGFISSDEYG 432
Query: 505 SSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYM--------TMDRP-----LSH 551
SSP D R+ S RS TP+S+ TPPAR G E Y+ T+ P LS
Sbjct: 433 SSPCDFRS--SFRSVTPDSLGHTPPAR---GEEELSNYICMGGKGPSTLTAPNGHYILSR 487
Query: 552 CGRSYR-----------RVSGD---AAQDLDRGLRKRTYSLTTP---ARQRPVPQPSSAS 594
G +R ++GD +A DLD RKRT+S T Q+ Q S AS
Sbjct: 488 GGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVAS 547
Query: 595 LDEYTLMRATF---SGSAGRLCPSCPASSPKVAYHPYPEDYGDIEI-----GSHRSSSSN 646
++EYT M + GS GRL S V YPE+ ++ G HR SS
Sbjct: 548 IEEYTEMMPAYPPGGGSGGRL--PGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSST 605
Query: 647 LGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAG 706
L DDGYMPM+PG A SG S DYMPMSP SVSAP+QI+ P
Sbjct: 606 LHTDDGYMPMSPGVAPVPSGRKG--SGDYMPMSPKSVSAPQQIINP-----IRRHPQRVD 658
Query: 707 PAGPAPTSAAGRTFPASGGGYKASSPAESS-PEDSGYMRMWCGS------------KLSM 753
P G S +G P GGG +SS + ++ P + Y ++W K +
Sbjct: 659 PNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPV 718
Query: 754 EHADGKLLP-NGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKA 812
E + GKLLP GDY+N+SP T +P D + P +P+ Y SLPRS+K
Sbjct: 719 ESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPV-----LSYYSLPRSFKH 773
Query: 813 PYTCG----GDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAG-------PTQP 861
G G Q++ +S+ GR+L + ++ S ++ + G G P+ P
Sbjct: 774 TQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSS---STSSDSLGGGYCGARLEPSLP 830
Query: 862 -PHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLP---SLPSMHE-----YPL--P 910
PH V P P + + R RPTRLSL G P +LP E PL P
Sbjct: 831 HPHHQVLQPHLPR--KVDTAAQTNSRLARPTRLSL-GDPKASTLPRAREQQQQQQPLLHP 887
Query: 911 PEPKSPGEYINIDFG---------------EPGARLSPPAPPL---------------LA 940
PEPKSPGEY+NI+FG P R P L
Sbjct: 888 PEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLG 947
Query: 941 SAASSSSLLSASSPASSLGSGTPGTSSDSRQR----SPLSDYMNLDFSSPKSPKPGAPSG 996
++ S LG PG +S R S DYM + S P+
Sbjct: 948 PGRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPA 1007
Query: 997 HPVGSLD---GLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATA 1053
PV D G+ + E S P + S+S +S+ P P EL +S +
Sbjct: 1008 APVSYADMRTGIAAEEVSLPRATMAAASSSSAASA--SPTGPQGAAEL--AAHSSLLGGP 1063
Query: 1054 QGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARV-ASPTSGVKRLSLME 1112
QGPG S+ + + +P + ++A+V + G +R E
Sbjct: 1064 QGPGGMSAFT---------------------RVNLSPNRNQSAKVIRADPQGCRRRHSSE 1102
Query: 1113 QVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRH 1172
S + + GA V GG SSE + KRH
Sbjct: 1103 TFSSTPSATRVGNTVPFGAGAAV----GGGGGSSSSSE-----------------DVKRH 1141
Query: 1173 NSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCP 1232
+SAS ENV LR GG P +P L G
Sbjct: 1142 SSASFENVWLRPGELGG-------------------------------APKEPAKLCGAA 1170
Query: 1233 GSGGSPMRRETSAGFQNGLNYIAID-VREEPGLP----PQPQPPPPPLP-QP---GDKSS 1283
G G +NGLNYI +D V++ P P+PQPPPPP P QP G+ SS
Sbjct: 1171 G------------GLENGLNYIDLDLVKDFKQCPQECTPEPQPPPPPPPHQPLGSGESSS 1218
Query: 1284 WGRT 1287
R+
Sbjct: 1219 TRRS 1222
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 298 bits (762), Expect = 3e-80
Identities = 348/1211 (28%), Positives = 491/1211 (40%), Gaps = 286/1211 (23%)
Query: 31 VRKCGYLRKQKHGHKRFFVLRGPGAGGDEATAGGGSAPQPPRLEYYESEKKWRSKAGA-- 88
V K GYLRKQKHGH+R+FVL+ +A P RLEYYE+ +K+R A
Sbjct: 79 VCKRGYLRKQKHGHRRYFVLKLE------------TADAPARLEYYENARKFRHSVRAAA 126
Query: 89 -----------------PKRVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQE 131
P+RVI L C ++++RADA++++LIAL+T+DEYFA+ AENE E
Sbjct: 127 AAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESE 186
Query: 132 QEGWYRALTDLVSEG---RAAAGDAPPAAAPAASCSASLPGALGGSAGAAGAEDSYGLVA 188
QE WY L+ L+ E R A P PAA A AA AE +
Sbjct: 187 QESWYLLLSRLILESKRRRCGTLGAQPDGEPAAL------------AAAAAAEPPF---- 230
Query: 189 PATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRC 248
Y++VWQV +KP+GLG K L+GV+RLCL+ + FV+LN E SV +QL++IRRC
Sbjct: 231 -----YKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC 285
Query: 249 GHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQS 308
GHS+ +FF+EVGRS V GPGELWMQ DD VVAQN+HE LE M+AL E+R R +S S
Sbjct: 286 GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALC-ADEYRARCRSYS 344
Query: 309 SGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGD 368
S H +++ ARRH LV L P G +RRSR + C +R +G+
Sbjct: 345 I-SIGAHLLTLLSARRHLGLVPLEPG--GWLRRSRFEQF-----------CHLRAIGDGE 390
Query: 369 ---------------------GGAAAGAAAAGARPVSVAGS---PLSPGPVR-------- 396
G R VSV S L+P P R
Sbjct: 391 DEMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAP 450
Query: 397 ---APLSR--SHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSS 451
A LS S + SG G G+ P G Q ++ + GS
Sbjct: 451 NNGARLSSEVSGSGSGNFGEEGN-----PQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ 505
Query: 452 SGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLR 511
+G GS G + G GQ S G ++G S S D G++ G
Sbjct: 506 GSNGQGSSSHSSGGNQ------CSGEGQ-GSRGGQGSNGQGSGGNQCSRDGQGTAGG--- 555
Query: 512 AFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQ-DLDRG 570
H S + P G GGG+ G + G SG + D +RG
Sbjct: 556 ----HGSGG----GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
Query: 571 --LRKRTY-SLTTPARQRPVPQPSSASLDEYTLMRATFSGSAG---RLCPSCPASSPKVA 624
L+KR+Y T ++Q+ +P P G +G RL + K
Sbjct: 608 KSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKEC 667
Query: 625 YHPYPEDYGDIEI------GSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPM 678
++ D EI G HR+ + + DD Y+PM PG A + S DYMPM
Sbjct: 668 KE--AKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVA-----TPLVSSSDYMPM 720
Query: 679 SPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPE 738
+P +VSA K+ + + P P P+ + +S
Sbjct: 721 APQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPA-------PSPPKAPDTNKEDDSKDN 773
Query: 739 DSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGV 798
DS DY+ ++P P + GG +
Sbjct: 774 DS----------------------ESDYMFMAPGAGAIPKNPRN------PQGGSSSKS- 804
Query: 799 PGCCYSSLPRSYKAPYTCGGDSDQYV--LMSSPVGRILEEERLEPQATPGPSQAAS-AFG 855
Y SLP +++ D+ +YV L +GR L++ E P AAS G
Sbjct: 805 -WSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDK---EVSYNWDPKDAASKPSG 860
Query: 856 AGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKS 915
G P SP +PS P + +A RP RLS Y + P+P+
Sbjct: 861 EGSFSKPGD-GGSPSKPSDHEP-----PKNKAKRPNRLSF-------ITKGYKIKPKPQK 907
Query: 916 P----------GEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTP-- 963
P +Y+N+DF + +++PA S G P
Sbjct: 908 PTHEQREADSSSDYVNMDF----------------------TKRESNTPAPST-QGLPDS 944
Query: 964 -GTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPS 1022
G ++ RQ S S+Y+N++F G P +P L LL +P
Sbjct: 945 WGIIAEPRQ-SAFSNYVNVEF--------GVPFPNPANDLSDLLR--------AIPRANP 987
Query: 1023 ASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAAT 1082
S S+ P PP P +A G A + GDY E+ F A T
Sbjct: 988 LSLDSARWPLPPLP--------------LSATGSNAIE-------EEGDYIEVIFNSAMT 1026
Query: 1083 PPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQG 1142
P +A A R + T + + + ++ L S+ +P A++++ + Q
Sbjct: 1027 PAMALA----DSAIRYDAETGRIYVVDPFSECC-MDISLSPSRCSEPPPVARLLQEEEQE 1081
Query: 1143 GRRRHS-SETF 1152
RR S S++F
Sbjct: 1082 RRRPQSRSQSF 1092
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 100 bits (249), Expect = 9e-21
Identities = 234/1013 (23%), Positives = 318/1013 (31%), Gaps = 212/1013 (20%)
Query: 314 THPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAA 373
T P S+ GA P+Q GL + L A K S T+S + +
Sbjct: 534 TVPASLEGAP-------FSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSP 586
Query: 374 GAAAAGARPVSVAGSPLSPG-PVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMS 432
A A G PL G P + S S + A + G L S ++
Sbjct: 587 EATLAKKS----LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLIT 642
Query: 433 MPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPH-------PPLPHPLHHGPGQRPSSGS 485
VA P + P ++ ++ G+ +Y P P HP+ G
Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVP 702
Query: 486 ASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTM 545
++ P P SP + A + PE I ++ P+ G G +
Sbjct: 703 TASENCPVAP----------SPQNTCAPLATLVLAPE-IPKSVPSPSLPPAGTPPGTKKV 751
Query: 546 DRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATF 605
D + S D G S T P P S+ T T
Sbjct: 752 DGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
Query: 606 SGSAGRLCP----SCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAA 661
GSAG P S P S + ++ P +S S G+ D P T +
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLP-------------ENSLSFQGSKDS--PATTHSP 856
Query: 662 LAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFP 721
S G+ P+SP V+ P + + + P GPA PAP A +
Sbjct: 857 TPPSPKGAPTPSAVTPLSPKGVTLPPK--ETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
Query: 722 ASGGGYKASSPA----ESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVT- 776
+S ++PA +SP G + S P G SP A T
Sbjct: 915 SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS---------PKGGPATPSPKWAPTP 965
Query: 777 -TGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILE 835
TPP P G P P + P + P GG + SP G
Sbjct: 966 PAATPPS-------PKGGP--ATPSPKGAPTPPAATPPSPKGGPA-----TPSPKGAPTP 1011
Query: 836 EERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRP--TRL 893
P +P S AA+ F G + PP PSP G P +G P T
Sbjct: 1012 PAVTPP--SPKGSPAATPFPKGASTPPAATPPSP----KGSPAATPLPKGAPTTPAATLP 1065
Query: 894 SLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASS 953
S +G P+ PS+ P PP P SP P S + +A+
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPP---------------SPKGGPATPSPKGAPMPPAATP 1110
Query: 954 PASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSP 1013
P+ G TP P ++P SPK G + P G+
Sbjct: 1111 PSPKGGLATP----------PHKGAPTTPAATPPSPKGGLATPPPKGA------------ 1148
Query: 1014 YPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPA--SAVATAQGPGAASSLSSDTGDNGD 1071
P P SP L PPP AP PP+ +AT GA ++
Sbjct: 1149 -PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT---------- 1197
Query: 1072 YTEMAFGVAATPPQPIA--APPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDP 1129
AATPP P A P P+ A PT+ A+ PP
Sbjct: 1198 -------PAATPPSPKGGLATPSPKGA----PTT------------------PAATPP-- 1226
Query: 1130 HRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGG 1189
P+GG S + +T TP SP A + S +GG
Sbjct: 1227 ---------SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 1190 VGVGPGGG-------------DEPPTSPRQLQPAPPLA----PQGRPWTPGQPGG----L 1228
+ P G P TSP + P PP A P+G P TP G
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 1229 VGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDK 1281
V P G+P T+ + G P P + P PP P K
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGG-----------PTTPSSKEGPTPPAATPSHK 1379
Score = 96.3 bits (238), Expect = 2e-19
Identities = 234/1015 (23%), Positives = 314/1015 (30%), Gaps = 182/1015 (17%)
Query: 302 PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQT---GLVRRSRTDSLAATPPAAKCSS 358
P S + SA P+S G V LPP +T +V ATP + +
Sbjct: 858 PPSPKGAPTPSAVTPLSPKG-------VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA 910
Query: 359 CRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVAL 418
+ ++S A A P G P SP P AP + T GG
Sbjct: 911 LSMTSSSP---------KKARATPAP-KGIPASPSPKGAPTPPAATPPSPKGG------- 953
Query: 419 LPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPG-PHPPLPHPLHHGP 477
PA + S A +PPAAT P S G + P P G P PP P P
Sbjct: 954 -PA--------TPSPKWAPTPPAATPP------SPKGGPATPSPKGAPTPPAATP----P 994
Query: 478 GQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGG 537
+ + S G+P+ P GS F S P A TPP+ G
Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSPAA--TPFPKGASTPP---AATPPSPKG---- 1045
Query: 538 EFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQ--PSSASL 595
AA L +G + TTPA P P+ P++ SL
Sbjct: 1046 -----------------------SPAATPLPKG------APTTPAATLPSPKGGPATPSL 1076
Query: 596 -DEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYM 654
T AT G P +P P G + H+ + + A
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA----T 1132
Query: 655 PMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPA--- 711
P +P LA P +PA+ P A P P PA
Sbjct: 1133 PPSPKGGLATPPPKGA------PTTPAAT-------PPSPKGGLATPPPKGAPTTPAATP 1179
Query: 712 PTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSP 771
P+ G P+ G ++PA + P G + A P G SP
Sbjct: 1180 PSPKGGLATPSPKGA--PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 772 SDAVTT--GTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSP 829
A TT TPP P + P SL P G + V SP
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Query: 830 VGRILEEERLEPQATPGPSQAASAFGAG-PTQPPHPVVPSPVRPSGGRPEGFLGQRGRAV 888
G P+ P P A G P PP P+P + P+G +
Sbjct: 1298 KG---GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG-----TPTL 1349
Query: 889 RPTRLSLEGLPSLPSMHEYPLPP--EPKSPGEYINIDFGEPGARLSPPAP---------- 936
T S +G P+ PS E P PP P G G ++PP+P
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKG----------GPAMTPPSPKRGPAIPSPK 1399
Query: 937 --PLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAP 994
P + S + ++P + G+ TP + L+ S K+P AP
Sbjct: 1400 GDPTSPAVIPLSPKKAPATPVTREGAATP-------SKGDLTPPAVTPVSLKKAPATSAP 1452
Query: 995 SGHPV--GSLDGLLSPEASSPYPPLPPRP-SASPSSSLQPPPPPPAPGELYRLPPASAVA 1051
G P S P + P P PP P + SSS + P PAP LP +
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
Query: 1052 TAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLM 1111
+ P SS P + + P A V SP +
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI----PPAMTVPSPKK-TPAIPTP 1567
Query: 1112 EQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKR 1171
++ + +AS PP P + S + VT SP A P
Sbjct: 1568 KEAPATPSSKEASSPP---------AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA 1618
Query: 1172 HNSASVENVSLRKSSEGGVGVGP-GGGDEPPTSPRQLQPAPPLAPQGRPWTPGQ--PGGL 1228
S E +G P G PP +P L+ + P +P G P
Sbjct: 1619 VTPPSPE--------KGPATPAPKGTPTSPPVTPSSLKDS-PTSPASVTCKMGATVPQAS 1669
Query: 1229 VGCPGSGGSPMRRET-SAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKS 1282
G P G +E A I R+ P PP P P K+
Sbjct: 1670 KGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKN 1724
Score = 85.1 bits (209), Expect = 4e-16
Identities = 191/836 (22%), Positives = 263/836 (31%), Gaps = 146/836 (17%)
Query: 432 SMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGS 491
S+P PPA T PG+ H P+ P + P+ S AS +
Sbjct: 733 SVPSPSLPPAGTPPGTKKVDG-----------ISHTSALAPVASSPKECPTEDS-GASAT 780
Query: 492 PSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSH 551
S G +L SP L S ++ + PP + G G D P+ +
Sbjct: 781 ASSKG--TLTYLADSPSPLGVSVSPQT-------KRPPTKKGSAG--------PDTPIGN 823
Query: 552 CGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGR 611
V + + S T P P P A T T G
Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP-PSPKGAP----TPSAVTPLSPKGV 878
Query: 612 LCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTP---GAALAGSGSG 668
P +P V P+P++ + S + TP G + S G
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
Query: 669 SCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSA---AGRTFPASGG 725
+ P SP A AA P GPA P+P A T P+ G
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998
Query: 726 GYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFS 785
G SP + + GS + G P TPP S
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP-------------PAATPP---S 1042
Query: 786 AALHPGGEPL-RGVPGCCYSSLPRSYKAPYT---CGGDSDQYVLMSSPVGRILEEERLEP 841
P PL +G P ++LP P T G + SP G
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG---------G 1093
Query: 842 QATPGPSQAASAFGAGP-------TQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLS 894
ATP P A A P PPH P+ + P+G G A P +
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG-----GLATPPPK-- 1146
Query: 895 LEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSP 954
G P+ P+ PP PK G +PP A ++ + SP
Sbjct: 1147 --GAPTTPA----ATPPSPK-------------GGLATPP-----PKGAPTTPAATPPSP 1182
Query: 955 ASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPY 1014
L + +P + + +P S L SPK P P+ P GL +P
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGA- 1240
Query: 1015 PPLPPRPSASPSSSLQPPPPPPAPGELYRLPPA--SAVATAQGPGAASS--LSSDTGDNG 1070
P P SP PPP AP PP+ +AT GA + ++ + G
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 1071 DYTEMAFGV----AATPPQPIAAP--------PKPEAARVASPTSGVKRLSLMEQVSGVE 1118
T G AATPP P +P P P A SP + G
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 1119 AFLQASQPPDP------HRGAKVIR-ADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKR 1171
+ + P P H+G + P+ G S + ++ V P+S PK+
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS------PKK 1414
Query: 1172 HNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPL-APQGRPWTPGQPG 1226
+ V + EG G P +P L+ AP AP+G P TP G
Sbjct: 1415 APATPV-------TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
Score = 77.4 bits (189), Expect = 8e-14
Identities = 165/754 (21%), Positives = 245/754 (32%), Gaps = 115/754 (15%)
Query: 650 DDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPR---------------- 693
D +P+ A S S +P+SP + A K + +P
Sbjct: 556 DPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVN 615
Query: 694 --------------------------AAAAAAAAVPSAGPAGPAPTSAAG-RTFPASGGG 726
AA + SA PAG APT+A G T+ +
Sbjct: 616 SSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASP 675
Query: 727 Y---KASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDF 783
+ S ++ P G + + E+ P ++ + + P
Sbjct: 676 FLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLA-TLVLAPEIPKSV 734
Query: 784 FSAALHPGGEP--LRGVPGCCY-SSLPRSYKAPYTCGGDSDQYVLMSSPVGRIL----EE 836
S +L P G P + V G + S+L +P C + +S G +
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 837 ERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRP--SGGRPEGFLGQRG------RAV 888
L +P + + G+ P + SPV P + PE L +G
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 889 RPTRLSLEGLPSLP-----SMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAA 943
PT S +G P+ S LPP+ +N+ F + G P S
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
Query: 944 SSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLD 1003
SSS + ++PA G P + S +P + ++P SPK G + P
Sbjct: 915 SSSPKKARATPAP---KGIPASPSPKGAPTPPA-------ATPPSPKGGPATPSP----- 959
Query: 1004 GLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLS 1063
+P + PP P A+PS P PP P P AT GA + +
Sbjct: 960 -KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS-----PKGGPATPSPKGAPTPPA 1013
Query: 1064 -SDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPT---SGVKRLSLMEQVSGVEA 1119
+ G F A+ P P A PP P+ + A+P + + + G A
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072
Query: 1120 FLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVEN 1179
P P P+GG S + TP SP H A
Sbjct: 1073 TPSLKGAPTPPAATP---PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129
Query: 1180 VSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPP--LA---PQGRPWTPG----QPGGLVG 1230
+ S +GG+ P G PT+P P+P LA P+G P TP P G +
Sbjct: 1130 AATPPSPKGGLATPPPKG--APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 1231 CPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSL 1290
P G+P + G + G P P P P P + +
Sbjct: 1188 TPSPKGAPTTPAATPPSPKG----GLATPSPKGAPTTPAATP---PSPKGGLATPSPKGA 1240
Query: 1291 GGLISAVGVGSTGGGCGGPGPGA-LPPANTYASI 1323
+A GG P GA PPA T S+
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
Score = 70.1 bits (170), Expect = 1e-11
Identities = 184/739 (24%), Positives = 252/739 (34%), Gaps = 122/739 (16%)
Query: 332 PPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLS 391
PPS G + A T PAA S + A+ GA AA P S G P +
Sbjct: 1202 PPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAPTTPAAT---PPSPKGGPAT 1257
Query: 392 PGPVRAPLSRSHT---LSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSL 448
P P AP + T L GG K A PA + P P A +P +
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA--VVTPPSPKGGPATSPPKGAPTPPAA 1315
Query: 449 SSSSGHGSGSYPPPPG-PHPP-LPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSS 506
+ S GS PPP G P PP + P G P++ + S+ G P+ P S E +
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT-TPSSKGGPTTP---SSKEGPTP 1371
Query: 507 PGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQD 566
P + + TP S P G + PLS V+ + A
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI----PLSPKKAPATPVTREGAAT 1427
Query: 567 LDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYH 626
+G T TP + P S+ AT S P+ SPK
Sbjct: 1428 PSKG--DLTPPAVTPVSLKKAPATSAPKGGP-----ATPSSKGDPTLPAVTPPSPKEP-- 1478
Query: 627 PYPEDYGDIEIGSHRSSSSNLGADDGYMPM--------TPGAALAGSGSGSCRSDDYMPM 678
P P+ +SSS A PM P + + S R D P
Sbjct: 1479 PAPKQVA--------TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530
Query: 679 S-------PASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASS 731
+ PA++ APK+ L P A + P PA P P A PA+ +ASS
Sbjct: 1531 ATLLSKKTPATL-APKEALIPPAMTVPS---PKKTPAIPTPKEA-----PATPSSKEASS 1581
Query: 732 PAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPG 791
P +P S Y +L + A P +P+ T P+ A P
Sbjct: 1582 PPAVTP--STYKGAPSPKELLIPPAVTSPSPKE-----APTPPAVTPPSPEKGPATPAPK 1634
Query: 792 GEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAA 851
G P P SSL S +P + ++ +G + + A GP+
Sbjct: 1635 GTPTS--PPVTPSSLKDSPTSPAS----------VTCKMGATVPQASKGLPAKKGPTALK 1682
Query: 852 SAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPP 911
A P P++ +P R +G ++ A P P+ P
Sbjct: 1683 EVLVA-PAPESTPIITAPTR------KGPQTKKSSATSP-----------------PICP 1718
Query: 912 EPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQ 971
+P + G G LS AP L SS + AS G P +S+
Sbjct: 1719 DPSAKN-------GSKGP-LSTVAPAPLLPVQKDSSKTAKGKDASHSPKG-PLAPPESKA 1769
Query: 972 RSPLSDY-MNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSS-- 1028
+PL+ P+S A PV P A SP P LPP+ PSS
Sbjct: 1770 STPLTAAAFEKVLPKPESASVSAAPSPPVSL------PLAPSPVPTLPPKQQFLPSSPGL 1823
Query: 1029 -LQPPPPPPAPGELYRLPP 1046
L+ P P AP + L P
Sbjct: 1824 VLESPSKPLAPADEDELLP 1842
Score = 42.0 bits (97), Expect = 0.004
Identities = 131/610 (21%), Positives = 197/610 (32%), Gaps = 106/610 (17%)
Query: 685 APKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGG----YKASSPAESSPEDS 740
A +L +A + AA+ GP P P S A + P S + + S S+P +
Sbjct: 21 AETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEV 80
Query: 741 GYMRMWCGSKLSMEHAD--GKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGV 798
+ + G+ L + A LPN +SP+ A+ +P A G P
Sbjct: 81 PFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPA-ALALASP----MIAPTLKGTPSSSA 135
Query: 799 PGCCYSSLPRSYK------------APYTCGGDSDQYVLMSSPV---------GRILEEE 837
P + P S + P +S + +S+P+ ++ E
Sbjct: 136 PLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEV 195
Query: 838 RLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEG 897
P+ TP P S T P H V P SG + + T L++
Sbjct: 196 VPNPKGTPSPPCIVS------TVPYHCVTPMASIQSG------VASLPQTTPTTTLAIAS 243
Query: 898 LPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASS 957
P + + P++PG L P P A + S+ SL +S +
Sbjct: 244 -PQVKDTTISSVLISPQNPG----------SLSLKGPVSPPAALSLSTQSLPVVTSSQKT 292
Query: 958 LGSGTP-------GTSSDSRQRSPLSDYMNLDFSSPKS-PKPGAPSGHPVGSLDGLLSPE 1009
G TP G+ +S L + P + P + S G P
Sbjct: 293 AGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPS 352
Query: 1010 ASSPYPPLPPRPSASPSSSLQPPPPPPA----PGELYRL---PPASA-VATAQGPGAASS 1061
S PPLP R P++ P P+ P + + P S VAT+ +S
Sbjct: 353 QRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTS 412
Query: 1062 LSSDTGDNGDY-----TEM-AFGVAATP-----PQPIAAPPKP--EAARVASPTSGVKRL 1108
L + N Y +M V TP P IAA P E A SP +
Sbjct: 413 LILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPI 472
Query: 1109 SLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHN 1168
S +E S + P +P T +TT PVSP
Sbjct: 473 SNIEPTSPAALVMAPVAPKEP--------------------STQVATTLRIPVSPPLPDP 512
Query: 1169 PKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGL 1228
N S +V ++ ++ + P + P SP Q P P P
Sbjct: 513 EDLKNLPS--SVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNS 570
Query: 1229 VGCPGSGGSP 1238
+ SP
Sbjct: 571 PSFQSTSSSP 580
Score = 35.0 bits (79), Expect = 0.48
Identities = 76/340 (22%), Positives = 111/340 (32%), Gaps = 81/340 (23%)
Query: 439 PPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSAS----------- 487
PPA TSP + + P GP P P P PSS S
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661
Query: 488 -------ASGSPSDPGFMSLDEYGSSPGD-----LRAFCSHRSNTPESIAETPP------ 529
+ G P+ G +L E +P + A T +S A +PP
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
Query: 530 ARDGGGGGEFYGYMTMDRPLSHCGR-SYRRVSGDAAQDLDRGL-----RKRTYSLTTPAR 583
A++G G PL + S + G A +G K + LT A
Sbjct: 1722 AKNGSKGPLS---TVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778
Query: 584 QRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSS 643
++ +P+P SAS+ PS P S P +A P P
Sbjct: 1779 EKVLPKPESASVS---------------AAPSPPVSLP-LAPSPVP-------------- 1808
Query: 644 SSNLGADDGYMPMTPGAALAGSGSGSCRSDD-----YMPMSPASVSAPKQILQPRAAAAA 698
L ++P +PG L +D+ +P P S P Q +
Sbjct: 1809 --TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPK 1866
Query: 699 AAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPE 738
+A +P P+ P + + G G ++ S ES PE
Sbjct: 1867 SAGIPVPTPSAKQPVTKNNK-----GSGTESDSD-ESVPE 1900
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 84.7 bits (208), Expect = 5e-16
Identities = 256/1101 (23%), Positives = 339/1101 (30%), Gaps = 222/1101 (20%)
Query: 364 ASEGDGGAAAGAAAAGARPVSVAGSP-LSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAG 422
A+E D A A +R +SV GS + P P +P ++ G ++ P G
Sbjct: 893 AAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSG-RLTPSPRG 951
Query: 423 GALQHSRSMSMPVAHSP-------PAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHH 475
G +P A SP P T GS S H S P PP H P H HH
Sbjct: 952 GPFNPGSGGPLP-ASSPASFDGPSPPDTRVGSREKSLYH---SGPLPPAHHHPPHHHHHH 1007
Query: 476 GPGQRPSSGSA--------SASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAET 527
P +P A GSP DP G P S TP + + +
Sbjct: 1008 APPPQPHHHHAHPPHPPEMETGGSPDDPPPRLA--LGPQPSLRGWRGGGPSPTPGAPSPS 1065
Query: 528 PPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPV 587
GGGGG G P + R + A R R R L +
Sbjct: 1066 HHGSAGGGGGSSQG------PALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGE 1119
Query: 588 PQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEI--------GS 639
PQ + P+ P P VA P + I I +
Sbjct: 1120 PQKGGG-----------LPPAPSPTSPASPQPPPAVAA---PSEKNSIPIPTIIIKAPST 1165
Query: 640 HRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAA 699
S S+ G+ P T G G G MSP S P + P A+ +
Sbjct: 1166 SSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPS-PSPVPTP-ASPSGP 1223
Query: 700 AAVPSAGPAGPAPTSAAGRTFPASGGGYKASS---PAESSPEDSGYMRMWCGSKLSMEHA 756
A + G A AA R + S+ ++ ED G + G+
Sbjct: 1224 ATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLR 1283
Query: 757 DGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTC 816
K + G + + G+ + GG Y + R+Y
Sbjct: 1284 HSKSIDEGMFSAEPYLRLESAGSGAGY-------GG----------YGAGSRAYGG---- 1322
Query: 817 GGDSDQYV--LMSSPVGRILEEERLEPQATPGPSQAA-------SAFGAGPTQPPHPVVP 867
GG S + L P+ L + L+P + G + AA S+ G G QPP P P
Sbjct: 1323 GGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPP-PRPP 1381
Query: 868 SPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPL-------PPEP--KSPGE 918
SP R A PT P H P+ PP+P + G
Sbjct: 1382 SP--------------RYEAPPPTPHHHS-----PHAHHEPVLRLWGASPPDPARRELGY 1422
Query: 919 YINIDFGEPGARLSPPA---------PPLLASAASSSSLLSASSPASSLGSGTPGTSSDS 969
+ E SPPA PP L PA G P S+
Sbjct: 1423 RAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAP 1482
Query: 970 RQRSPLSDYMN-LDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSS 1028
+ L ++ L+ P++P G P G+ P PP P P AS +
Sbjct: 1483 EEPERLPLHVRFLENCQPRAPVTSG-RGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENG 1541
Query: 1029 LQ----PPPPPPAPGE------LYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFG 1078
L PPP P E + LPP + + + D A
Sbjct: 1542 LPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATP 1601
Query: 1079 VAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRA 1138
+ PP +AA P + +S TS ++ + Q G A PP P A A
Sbjct: 1602 LPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQ--GASAAPGDPHPPGPPAPAAPAPA 1659
Query: 1139 DPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGD 1198
PQ G T S V S S + +P S++ SL G G G G G
Sbjct: 1660 APQPGPDPPPG-TDSGIEEVD--SRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGA 1716
Query: 1199 EPPTSPRQLQ----------------PAPPLAPQ--------GRPW------TPGQPGGL 1228
+ P L P PP PQ GR PG GGL
Sbjct: 1717 GVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGL 1776
Query: 1229 VGCPGSGGSPMRRETSAGFQNGLNYIAID-----------VREEPGLPPQPQP------- 1270
P + SP T AG L A V EP +PP P P
Sbjct: 1777 RD-PVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPR 1835
Query: 1271 -----------PPPPLPQP---------------------GDKSSWGRTRSLGGLISAVG 1298
PPPPLP P +G + + GG +
Sbjct: 1836 KLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWAR 1895
Query: 1299 VGSTGGGCGGPGPGALPPANT 1319
GS GGG G + P T
Sbjct: 1896 GGSGGGGDSHHGGASYVPERT 1916
Score = 62.4 bits (150), Expect = 3e-09
Identities = 190/823 (23%), Positives = 255/823 (30%), Gaps = 189/823 (22%)
Query: 584 QRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHR-- 641
Q+P P PS R + + +L A+ ++ P G +G HR
Sbjct: 800 QQPAPVPSMEK------KRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPK 853
Query: 642 -------SSSSNLGADDGY-----MPMTPGAALAGSGSGSCRSDDYMPMSPA-----SVS 684
S + A Y +P PG L G+ D PA S+S
Sbjct: 854 GFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLS 913
Query: 685 APKQILQPRAAAAAAAAVPSAGPAGPA------PTSAAGRTFPASGGGYKASSPAE---S 735
P P + P + P P+ P+ G P SGG ASSPA
Sbjct: 914 VPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGP 973
Query: 736 SPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPL 795
SP D+ GS+ + G L P + P PP HP P
Sbjct: 974 SPPDTR-----VGSREKSLYHSGPLPPAHHH---PPHHHHHHAPPPQPHHHHAHPPHPPE 1025
Query: 796 RGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPG---PSQAAS 852
G PR L P + P TPG PS S
Sbjct: 1026 METGGSPDDPPPR----------------LALGPQPSLRGWRGGGPSPTPGAPSPSHHGS 1069
Query: 853 AFGAGPTQ----------PPHPVVPSPVRPS-GGRPEGFLGQRGRAVRPTRLSLEGLPSL 901
A G G + PP + P+ GR G++G V+ T+ +EG P
Sbjct: 1070 AGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGR-----GRKGPLVKQTK--VEGEPQK 1122
Query: 902 PSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSG 961
LPP P P + SP PP +A+ + +S+ P ++
Sbjct: 1123 GG----GLPPAP------------SPTSPASPQPPPAVAAPSEKNSI-----PIPTIIIK 1161
Query: 962 TPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRP 1021
P TSS R S + + P P+P G G SP + P+PP P
Sbjct: 1162 APSTSSSGRS----SQGSSTEAEPPTQPEPTGGGG------GGGSSPSPAPAMSPVPPSP 1211
Query: 1022 SASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASS---------LSSDTGDNGDY 1072
S P+ + P PA + A+ V A+ G + LS+D GD D
Sbjct: 1212 SPVPTPA---SPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDE-DG 1267
Query: 1073 TEMAFGVAATP-PQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHR 1131
+ G A P P+ + E A P RL +G + S
Sbjct: 1268 GDGGLGTGAAPGPRLRHSKSIDEGMFSAEP---YLRLESAGSGAGYGGYGAGS------- 1317
Query: 1132 GAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSA-SVENVSLRKSSEGGV 1190
RA GG + V P++ A + +L++SSEGG
Sbjct: 1318 -----RAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGG- 1371
Query: 1191 GVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNG 1250
G PP P APP P L S P RRE G++ G
Sbjct: 1372 ----GAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRE--LGYRAG 1425
Query: 1251 LNYIAIDVREEPGLPPQPQ----------PP--------------PPPLPQPGDKSSWG- 1285
L +E LP P PP PP P PG W
Sbjct: 1426 LG------SQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRS 1479
Query: 1286 -----------RTRSLGGLISAVGVGSTGGGCGGPGPGALPPA 1317
R L V S G GPG PP+
Sbjct: 1480 AAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPS 1522
Score = 41.2 bits (95), Expect = 0.007
Identities = 95/387 (24%), Positives = 125/387 (32%), Gaps = 79/387 (20%)
Query: 845 PGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSL-PS 903
PGPS G P P P+ V +G +G L R + PT G ++ P
Sbjct: 1770 PGPS-------GGLRDPVTPTSPT-VSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPE 1821
Query: 904 MHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTP 963
+ PLP P + + + G PG PP PPL A + A+ AS +
Sbjct: 1822 VPPVPLPTASSLPRKLLPWEEG-PG----PPPPPLPGPLAQPQASALATVKASII----- 1871
Query: 964 GTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLS--PEASSPYP------ 1015
S S L + + P SG S G S PE +S
Sbjct: 1872 -----SELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSD 1926
Query: 1016 ----PLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGD 1071
L +P +S + PP PP P P A+A A P A+SS +S G
Sbjct: 1927 DSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGV 1986
Query: 1072 YTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDP-H 1130
EM + P P P A S + L P P +
Sbjct: 1987 EFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPIL-----------------PSGPLY 2029
Query: 1131 RGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGV 1190
G IR P GG + + P +P F V GG+
Sbjct: 2030 PGLFDIRGSPTGG----------AGGSADPFAPVF--------------VPPHPGISGGL 2065
Query: 1191 GVGPGGGDEPPTSPRQLQPAPPLAPQG 1217
G G G SP +L PP P G
Sbjct: 2066 G-GALSGASRSLSPTRLLSLPPDKPFG 2091
Score = 39.3 bits (90), Expect = 0.026
Identities = 225/956 (23%), Positives = 288/956 (30%), Gaps = 253/956 (26%)
Query: 288 LEAMKALKE-LFEFRPRSKSQSSGSSATHPISVPGARRHH-------HLVNLPPSQTGLV 339
L K++ E +F P + +S+GS A + G+R + LPP LV
Sbjct: 1282 LRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRP--LV 1339
Query: 340 RRSRTDSLAATPPAAKCSSCRVRTASEG-DGGAAAGAAAAGARPVSVAGSPL----SPGP 394
+L P + R R E +GG A P A P SP
Sbjct: 1340 HPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHA 1399
Query: 395 VRAPLSRSHTLS---------GGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSP 445
P+ R S G G GS+ LPA RS+ + PP A
Sbjct: 1400 HHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAAR-RSL---LHRLPPTAPGV 1455
Query: 446 GSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPS---------------SGSASASG 490
G L G PP PHP + P + P + S G
Sbjct: 1456 GPLLLQLG------TEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRG 1509
Query: 491 SPSD--PGFMSLDEYGS---SPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTM 545
PS+ PG S SP RA S + P + P GEF +
Sbjct: 1510 PPSEDGPGVPPPSPRRSVPPSPTSPRA--SEENGLPLLVLPPPAPSVDVEDGEFLFVEPL 1567
Query: 546 DRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSA-----------S 594
PL S+ + L T + TP PVP P+ A S
Sbjct: 1568 PPPLEF-SNSFEKPESPLTPGPPHPLPD-TPAPATPLP--PVPPPAVAAAPPTLDSTASS 1623
Query: 595 LDEYTLMRATFSGSA----------GRLCPSCPA-SSPKVAYHPYPEDYGDIEIGSHRSS 643
L Y AT + A G P+ PA ++P+ P P IE RSS
Sbjct: 1624 LTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSS 1683
Query: 644 S-------------SNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQIL 690
S S+L A+ G G A AG SG D Y+ L
Sbjct: 1684 SDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAY-----------L 1732
Query: 691 QPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSK 750
+A ++ P P P+ GR ASGG P SG +R
Sbjct: 1733 DGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGG---------LRPGPSGGLR------ 1777
Query: 751 LSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSY 810
D + + TG D A G P GV G
Sbjct: 1778 --------------DPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAG---------- 1813
Query: 811 KAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASA-------FGAGPTQPPH 863
PV +EP+ P P AS+ + GP PP
Sbjct: 1814 -----------------GPVA-------VEPEVPPVPLPTASSLPRKLLPWEEGPGPPP- 1848
Query: 864 PVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINID 923
P +P P+ +P+ +A + LS + S P + G D
Sbjct: 1849 PPLPGPL----AQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARG-GSGGGGD 1903
Query: 924 FGEPGARLSPPAPPLL----ASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYM 979
GA P L S S SSLL S P SSL P
Sbjct: 1904 SHHGGASYVPERTSSLQRQRLSDDSQSSLL--SKPVSSLFQNWP---------------- 1945
Query: 980 NLDFSSPKSPKPGAPSGHPV----GSLDGLLSPEASS-----------PYPPLPPRPSAS 1024
K P P P+G V + G SP ASS + PP +
Sbjct: 1946 -------KPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRA 1998
Query: 1025 PSSSLQPP-----PPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGV 1079
PS SL P P P P L LP PG S TG G
Sbjct: 1999 PSPSLLPASEHKVSPAPRPSSLPILPSGPLY-----PGLFDIRGSPTGGAGG-------- 2045
Query: 1080 AATPPQPIAAPPKPE-AARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAK 1134
+A P P+ PP P + + SG R + S PPD GAK
Sbjct: 2046 SADPFAPVFVPPHPGISGGLGGALSGASR--------SLSPTRLLSLPPDKPFGAK 2093
Score = 32.0 bits (71), Expect = 4.1
Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 11/60 (18%)
Query: 1265 PPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYASID 1324
PP PP PP P SS GR S GG PG G PA++ AS D
Sbjct: 923 PPTTSPPEPPYSTPPVPSSSGRLTP-----------SPRGGPFNPGSGGPLPASSPASFD 971
Score = 30.8 bits (68), Expect = 9.1
Identities = 44/165 (26%), Positives = 62/165 (37%), Gaps = 39/165 (23%)
Query: 906 EYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLL---------SASSPAS 956
E + P +SP +Y G PG L+ P L A++ +S +L +ASS A
Sbjct: 404 EQDVVPFQESP-KYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAP 462
Query: 957 SLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPS--GHPVGSLDGLLSPEASSPY 1014
SG+ G S S + LS SSP+ + +PS HP +
Sbjct: 463 GPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDA------------- 509
Query: 1015 PPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAA 1059
+P PSSS P R PA + GPG +
Sbjct: 510 ---KRQPRGRPSSSGTP-----------REGPAGGTGGSGGPGGS 540
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 83.2 bits (204), Expect = 2e-15
Identities = 232/979 (23%), Positives = 311/979 (31%), Gaps = 144/979 (14%)
Query: 360 RVRTASEGDGGAAAGAAAAGAR----PVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSK 415
R R + G GA A GA P AG P PG V A +G G RGS+
Sbjct: 310 RGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGE-----AGPQGPRGSE 364
Query: 416 VALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPL-PHPLH 474
G + + A +P A PG+ ++ G P PG P P
Sbjct: 365 GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424
Query: 475 HGPGQRPSSGSASASGSPSD------PGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETP 528
PG + +SG A GS D PG + + G+ + P + P
Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484
Query: 529 PARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVP 588
R G G F G + P G R G A G R P +
Sbjct: 485 GERGGPGSRGFPGADGVAGPKGPAGE--RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTG 542
Query: 589 QPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLG 648
P S D T +G GR P P + A G + + ++ G
Sbjct: 543 SPGSPGPDGKTGPPGP-AGQDGRPGPPGPPGARGQA--------GVMGFPGPKGAAGEPG 593
Query: 649 -ADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGP 707
A + +P PGA G + P PA + + P A + +P GP
Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQG--PPGPAGPAGERGEQGP-AGSPGFQGLP--GP 648
Query: 708 AGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYL 767
AGP P A G A P+ + E R + G + ++ G P G
Sbjct: 649 AGP-PGEAGKPGEQGVPGDLGAPGPSGARGE-----RGFPGER-GVQGPPGPAGPRG--A 699
Query: 768 NVSPS------DAVTTGTPPDFFSAALH--PGGEPLRGVPGCCYSSLPRSYKAPYTCGGD 819
N +P DA G P + L PG G+PG P GD
Sbjct: 700 NGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPG------------PKGDRGD 747
Query: 820 SDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFG-AGPTQPPHPV----------VPS 868
+ SP G+ P PGP+ A G +GP+ P P P
Sbjct: 748 AGPKGADGSP-GKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG 806
Query: 869 PVRPSG-GRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEP 927
P P+G P G GQ G P +G PP P P G P
Sbjct: 807 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAG---------PPGPAGPA-------GPP 850
Query: 928 GARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPK 987
G + AP + S+ + P ++ G PG S ++ P P+
Sbjct: 851 GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPR 910
Query: 988 SPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPP-PPAPGELYRLPP 1046
P+G P E P PP P SP + P P P +
Sbjct: 911 GET--GPAGRP---------GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959
Query: 1047 ASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAP----PKPEAARVASPT 1102
+ +G L +G+ G PP P+ P P E+ R +P
Sbjct: 960 VVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAP- 1018
Query: 1103 SGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADP----QGGRRRHSSETFSSTTTV 1158
G + + G + + P P GA P G+ ET
Sbjct: 1019 -GAEGSPGRDGSPGAKGDRGETGPAGPP-GAPGAPGAPGPVGPAGKSGDRGET-GPAGPA 1075
Query: 1159 TPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPG-----GGDEPPTSPRQLQPAP-- 1211
PV P A P + + + G+ G G PP SP + P+
Sbjct: 1076 GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS 1135
Query: 1212 -PLAPQGRPWTPGQPG--GLVGCPGSGGSP-MRRETSAGFQNGLNYIAIDVREEPGLPPQ 1267
P P+G P + G PG GL G PG G P R T G PG P
Sbjct: 1136 GPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG----------PPGPPGP 1185
Query: 1268 PQPPPPP--------LPQP 1278
P PP PP LPQP
Sbjct: 1186 PGPPGPPSAGFDFSFLPQP 1204
Score = 72.0 bits (175), Expect = 4e-12
Identities = 214/887 (24%), Positives = 262/887 (29%), Gaps = 175/887 (19%)
Query: 365 SEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHT--LSGGCGGRGSKVALLPAG 422
++G GA A A G P PG P S G G G+K P G
Sbjct: 396 AKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG 455
Query: 423 --GALQHSRSMSMPVAHSPPAATS-PGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGP-G 478
G + A P T PG G GS +P G P GP G
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGP------KGPAG 509
Query: 479 QRPSSGSASASGSPSD---------PGFMSLDEYGSSPGDLRAFCSHRSNTPESIAET-- 527
+R S G A GSP + PG L SPG ++ P +
Sbjct: 510 ERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP-----DGKTGPPGPAGQDGR 564
Query: 528 --PPARDGGGGGEFYGYMTMDRPLSHCGRSYRR----------VSGDAAQDLDRGLRKRT 575
PP G G G M P G + G A +D + G +
Sbjct: 565 PGPPGPPGARGQA--GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622
Query: 576 YSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYG-- 633
PA +R P+ + F G G P P + K P D G
Sbjct: 623 -GPAGPAGERGEQGPAGSP---------GFQGLPGPAGP--PGEAGKPGEQGVPGDLGAP 670
Query: 634 -DIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQP 692
R G P P A G+ + D P +P S AP P
Sbjct: 671 GPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP 730
Query: 693 RAAAAAAAAVPS-----AGPAG-------------------PAPTSAAGRTFPASGGGYK 728
AA P AGP G P P A G + G
Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790
Query: 729 ASSPAESSPEDSGYMRMWCGSKLS-MEHADGKLLPNGDYLNVSPSDAVTTGT--PPDFFS 785
+ A +P D G + + ADG+ G+ P DA G PP
Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE-----PGDAGAKGDAGPPGPAG 845
Query: 786 AALHPGGEPLRGVPGCC----YSSLPRSYKAPYTCG-----GDSDQYVLMSSPVGRILEE 836
A PG G PG + P + P G G S P G +E
Sbjct: 846 PAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGN-AGPPGPPGPAGKE 904
Query: 837 ERLEPQATPGPSQAASAFGAGPTQPPHPV----VPSPVRPSGGR----PEGFLGQRGRAV 888
P+ GP A GP PP P P P+G P+G GQRG
Sbjct: 905 GGKGPRGETGP--AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVG 962
Query: 889 RPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSL 948
P + G P LP P P + G PG P PP LA S
Sbjct: 963 LPGQRGERGFPGLPGPSGEPGKQGPSGASG----ERGPPG----PMGPPGLAGPPGESGR 1014
Query: 949 LSASSPASSLG-SGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGH--------PV 999
A S G G+PG D + P +P +P P P+G P
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP--GAPGAPGPVGPAGKSGDRGETGPA 1072
Query: 1000 GSLDGLLSPEASSPYPPLPPRPSASPS--------------SSLQ-PPPPPPAPGEL--- 1041
G + A P P PR + S LQ PP PP +PGE
Sbjct: 1073 GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS 1132
Query: 1042 -------YRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPE 1094
R PP S A A G + L G G PP P P P
Sbjct: 1133 GASGPAGPRGPPGS--AGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPP- 1189
Query: 1095 AARVASPTSGVKRLSLMEQVSGVEAFLQASQPPD--PHRGAKVIRAD 1139
P++G F QPP H G + RAD
Sbjct: 1190 ----GPPSAGFD-------------FSFLPQPPQEKAHDGGRYYRAD 1219
Score = 70.5 bits (171), Expect = 1e-11
Identities = 232/972 (23%), Positives = 303/972 (31%), Gaps = 188/972 (19%)
Query: 445 PGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYG 504
PG + S G P PGP P PG+ +SG G P PG D
Sbjct: 178 PGPMGPSGPRGLPGPPGAPGPQGFQGPPGE--PGEPGASGPMGPRGPPGPPGKNGDDGEA 235
Query: 505 SSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAA 564
PG P+ P G G+ +D G + + G+
Sbjct: 236 GKPGRPG---ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK--GEPG 290
Query: 565 QDLDRGLRKRTYSLTTPA-RQRP-VPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPK 622
+ G + P R RP P P+ A ++ +G+AG P+ PA P
Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA------TGAAGPPGPTGPAGPPG 344
Query: 623 VAYHPYPEDYGDI-EIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPA 681
+P G E G S P PG A A +G+ +D P +
Sbjct: 345 -----FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADG-QPGAKG 398
Query: 682 SVSAPKQILQPRAAAAAAAAVPSA-GPAGP----APTSAAGRTFPASGGGYKASSPAESS 736
+ AP A A P A GP+GP P G + G K + A+
Sbjct: 399 ANGAP--------GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE 450
Query: 737 PEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLR 796
P G +GK G+ P G P + GG R
Sbjct: 451 PGPVGVQ-----GPPGPAGEEGKRGARGE-----PGPTGLPGPPGE-------RGGPGSR 493
Query: 797 GVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGA 856
G PG + P+ G + P G E R PG + G+
Sbjct: 494 GFPGADGVAGPKGPAGERGSPGPA-------GPKGSPGEAGRPGEAGLPGAKGLTGSPGS 546
Query: 857 ----GPTQPPHPVV----PSPVRPSGGRPE----GFLGQRGRAVRPTRLSLEGLPSLPSM 904
G T PP P P P P G R + GF G +G A P + G+P P
Sbjct: 547 PGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA 606
Query: 905 ---------HEYPLPPEPKSPGEYINIDFGEPGARLSP-------PA-PPLLASAASSSS 947
PP P P + GE G SP PA PP A
Sbjct: 607 VGPAGKDGEAGAQGPPGPAGPAG----ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQG 662
Query: 948 L---LSASSPASSLGS-GTPGTSSDSRQRSPL-----SDYMNLDFSSPKSPKPGAPSGHP 998
+ L A P+ + G G PG P + D + + PGAP
Sbjct: 663 VPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQG 722
Query: 999 VGSLDGLLSPEASSPYP-PLPPRPSASPSSS---------------LQPPPPPPAPGELY 1042
L G+ ++ P P R A P + + PP P APG+
Sbjct: 723 APGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKG 782
Query: 1043 RLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQP--IAAPPKPEAARVAS 1100
P+ GP A D G+ G PP P A PP + A
Sbjct: 783 ESGPSGPA----GPTGARGAPGDRGEPG------------PPGPAGFAGPPGADGQPGAK 826
Query: 1101 PTSGVKRLSLMEQVSGVEAFLQASQPPDP-----HRGAKVIR--ADPQGGRRRHSSETFS 1153
G + +G + PP P GAK R A P G ++
Sbjct: 827 GEPGDAGA---KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG-----ATGFPG 878
Query: 1154 STTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPL 1213
+ V P PS P + EGG G P G P P ++ P P
Sbjct: 879 AAGRVGPPGPSGNAGPPGPPGPA--------GKEGGKG--PRGETGPAGRPGEVGPPGPP 928
Query: 1214 APQGRPWTPGQ--PGGLVGCPGSGGSPMRRETSA--GFQNGLNYIAI-DVREEPGL---- 1264
P G +PG P G G PG G +R G + + + EPG
Sbjct: 929 GPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPS 988
Query: 1265 -------PPQPQPPP----PPLPQ-----PGDKSSWGRTRSLG--GLISAVGVGSTGGGC 1306
PP P PP PP PG + S GR S G G G G
Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048
Query: 1307 GGPG-PGALPPA 1317
G PG PG + PA
Sbjct: 1049 GAPGAPGPVGPA 1060
Score = 58.2 bits (139), Expect = 5e-08
Identities = 120/476 (25%), Positives = 150/476 (31%), Gaps = 83/476 (17%)
Query: 858 PTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPG 917
PT V P +G R G RG A P R + G P LP PP P P
Sbjct: 102 PTDQETTGVEGPKGDTGPR-----GPRGPAGPPGRDGIPGQPGLPG------PPGPPGPP 150
Query: 918 EYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSD 977
G PG L P L+ S S P SG G P
Sbjct: 151 -------GPPG--LGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG- 200
Query: 978 YMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPP--- 1034
F P PG P G P S G + P PP PP + + +P P
Sbjct: 201 -----FQGP----PGEP-GEPGAS--GPMGPRG----PPGPPGKNGDDGEAGKPGRPGER 244
Query: 1035 -PPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEM----AFGVAATPPQPIAA 1089
PP P LP + + +G S L GD G + G P Q
Sbjct: 245 GPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPR 304
Query: 1090 PPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHR-----------GAKVIRA 1138
E R +P R G + A+ PP P GAK A
Sbjct: 305 GLPGERGRPGAPGPAGAR--------GNDGATGAAGPPGPTGPAGPPGFPGAVGAKG-EA 355
Query: 1139 DPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPG-GG 1197
PQG R + P P+ A P + A + + + G+ PG G
Sbjct: 356 GPQGPRGSEGPQGVRGEP--GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPG 413
Query: 1198 DEPPTSPRQLQPAPPLAPQGRPWTPGQPG--GLVGCPGSGGSPMRRETSAGFQNGLNYIA 1255
P+ P+ P P P+G PG PG G G G G P+ + G
Sbjct: 414 ARGPSGPQ--GPGGPPGPKGNSGEPGAPGSKGDTGAKGEPG-PVGVQGPPG--------- 461
Query: 1256 IDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGP 1311
EE + +P P LP P + +R G G G G PGP
Sbjct: 462 -PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGP 516
Score = 49.3 bits (116), Expect = 2e-05
Identities = 159/687 (23%), Positives = 198/687 (28%), Gaps = 124/687 (18%)
Query: 685 APKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMR 744
+P + +P A A + P P P G PA G + +G M
Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMG 581
Query: 745 MWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTP--PDFFSAALHPGGEPLRGVPGCC 802
P P A G P P A G +G PG
Sbjct: 582 F----------------PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPA 625
Query: 803 YSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGA------ 856
+ R + P S + + P G E + Q PG A GA
Sbjct: 626 GPAGERGEQGP----AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681
Query: 857 ----GPTQPPHPVVPSPVRPSGGRP--EGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLP 910
G PP P P R + G P +G G G P GL +P
Sbjct: 682 PGERGVQGPPGPAGP---RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738
Query: 911 PEPKSPGEYINIDFGEPGARLSPP-----------APPLLASAASSSSLLSASSPASSLG 959
P PK D G GA SP PP A A S PA G
Sbjct: 739 PGPKGDRG----DAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794
Query: 960 S-GTPGTSSDSRQRSPLSDYMNLDFSSPKSP--KPGAPSGHP--VGSLDGLLSPEASSPY 1014
+ G PG + P F+ P +PGA G P G+ P + P
Sbjct: 795 ARGAPGDRGEPGPPGPAG------FAGPPGADGQPGA-KGEPGDAGAKGDAGPPGPAGPA 847
Query: 1015 -PPLPPRPSASPSS-----SLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGD 1068
PP P +P + S PP PG R+ P A PG + G
Sbjct: 848 GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE-GG 906
Query: 1069 NGDYTEMAFGVAATPPQPIAAPPKPEAARVASP----------TSGVKRLSLMEQVSGVE 1118
G E G A P + P A SP T G + ++ V G+
Sbjct: 907 KGPRGET--GPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964
Query: 1119 AFL-QASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASV 1177
+ P P + + P G P+ P P +
Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG--------PMGPPGLAGPPGESGR-- 1014
Query: 1178 ENVSLRKSSEGGVGV-GPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGG 1236
EG G G G D P + P P G P PG PG VG G G
Sbjct: 1015 ---------EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP-VGPAGKSG 1064
Query: 1237 SPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGR--TRSLGGLI 1294
R ET G P P + P P GDK G R + G
Sbjct: 1065 D--RGETGPAGPAG-----------PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111
Query: 1295 SAVGVGSTGGGCGGPG----PGALPPA 1317
G+ G G PG GA PA
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPA 1138
Score = 48.5 bits (114), Expect = 4e-05
Identities = 138/567 (24%), Positives = 156/567 (27%), Gaps = 145/567 (25%)
Query: 302 PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV 361
P K +S S P GA PP G D P AK
Sbjct: 778 PGDKGESGPSGPAGPTGARGAPGDRGEPG-PPGPAGFAGPPGADG----QPGAK------ 826
Query: 362 RTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPA 421
GD GA A G P AG P G V AP G G RGS
Sbjct: 827 --GEPGDAGAKGDAGPPG--PAGPAGPPGPIGNVGAP--------GAKGARGSA------ 868
Query: 422 GGALQHSRSMSMPVAHSPPAATS-PGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR 480
PP AT PG+ G PPGP P P G G R
Sbjct: 869 ----------------GPPGATGFPGAAGRVGPPGPSGNAGPPGP--PGPAGKEGGKGPR 910
Query: 481 PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY 540
+G A G PG SPG A+ P G G
Sbjct: 911 GETGPAGRPGEVGPPGPPGPAGEKGSPG----------------ADGPAGAPGTPG---- 950
Query: 541 GYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL 600
P G+ R V G Q +RG P +Q P
Sbjct: 951 -------PQGIAGQ--RGVVGLPGQRGERGFPGLPGPSGEPGKQGP-------------- 987
Query: 601 MRATFSGSAGRLCPSCPASSPKVAYHPYP---EDYGDIEIGSHRSSSSNLGADDGYM-PM 656
SG++G P P P +A P E E R S D G P
Sbjct: 988 -----SGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA 1042
Query: 657 TPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGP-APTSA 715
P A G+ P+ PA S + P A V + GPAGP P
Sbjct: 1043 GPPGAPGAPGAPG-------PVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095
Query: 716 AGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAV 775
G T G K G P G PS A
Sbjct: 1096 KGETGEQGDRGIKGHR--------------------GFSGLQGPPGPPGSPGEQGPSGAS 1135
Query: 776 TTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILE 835
P +A PG + L G+PG P P GD + PVG
Sbjct: 1136 GPAGPRGPPGSAGAPGKDGLNGLPG------PIGPPGPRGRTGD-------AGPVG---P 1179
Query: 836 EERLEPQATPGPSQAASAFGAGPTQPP 862
P PGP A F P QPP
Sbjct: 1180 PGPPGPPGPPGPPSAGFDFSFLP-QPP 1205
Score = 32.0 bits (71), Expect = 4.1
Identities = 36/125 (28%), Positives = 39/125 (31%), Gaps = 32/125 (25%)
Query: 1197 GDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAI 1256
G E PT P G P P G G PG G P
Sbjct: 98 GSESPTDQETTGVEGPKGDTG----PRGPRGPAGPPGRDGIP------------------ 135
Query: 1257 DVREEPGLPPQPQPPPPPLPQPG------DKSSWGRTRSLGGLISAVGVGSTGGGCGGPG 1310
+PGLP P PP P PG + S+G G IS G G G PG
Sbjct: 136 ---GQPGLPGPPGPPG-PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPG 191
Query: 1311 PGALP 1315
P P
Sbjct: 192 PPGAP 196
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 82.0 bits (201), Expect = 3e-15
Identities = 189/761 (24%), Positives = 243/761 (31%), Gaps = 173/761 (22%)
Query: 677 PMSPASV-------SAPKQILQPRAAAAAAAAVPSAGP-AGPAPTSAAGRTFPASGGGYK 728
P++PA++ + ++ L RA A +P + P AGP TS PASG G +
Sbjct: 38 PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP----PASGRGER 93
Query: 729 ASSPAESSP-------EDSGYMRMWC----GSKLSMEH--ADGKLL--PNGDYLNVSP-- 771
A +SP SG R G ++S E A GK P L+
Sbjct: 94 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 153
Query: 772 -SDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPV 830
+ T GTP + G + G+P S+ PR P T G
Sbjct: 154 DTSGPTPGTPSPAMARRSRAAGTEV-GLPRPAPSARPR----PPTEGPRKSVSSASEHST 208
Query: 831 GRILEEERLEPQATPG---PSQAASAFGAGPTQPPHPVVPS-------PVRPSGGRPEGF 880
R P A G P+ + + A P P PS P PS +P+G
Sbjct: 209 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 268
Query: 881 LGQRGRAVRPTR---------LSLEGL----PSLPSMHEYP-----LPPEPKSPGEYINI 922
R V P R LS L PS P P LP P +P
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT 328
Query: 923 DFGEPGARL------SPPA------PPLLASAASSSSLLSASSPASSLGSGTPGTSSDSR 970
G P + SPP PP A + L + SP +S T S
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388
Query: 971 QRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPY--------PPL--PPR 1020
+ + FS P SP AP P +SP A+ P PPL PP
Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPP---VSPSATPPSQAPPSLAAPPLQVPPS 445
Query: 1021 PSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASS--LSSDTGDNGDYTEMA-F 1077
P ASP S PPP AP L P A Q P A ++ L + + A F
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 1078 GVAAT-PPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKV- 1135
+A+ P P+A PP +A+P L + +PP P V
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPL-----LQVPPSPPASPTLQAPRRPPTPGPDTSVS 560
Query: 1136 -------IRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEG 1188
+ P R S T S P A + S E EG
Sbjct: 561 GPRLTLALAPGPPPPPSRSPSSTLSG--------PDLAGHSSSATSTPEELRGYDSGPEG 612
Query: 1189 GVGVGPGGGDE-----PPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRET 1243
G P E P R PAPPLA +G P P P T
Sbjct: 613 GAAASPPPDAELAACHPAAWSRG--PAPPLAFRGAPGAP--------------LPWPPAT 656
Query: 1244 SAGFQNGLNYIAIDVREEPGLPPQPQPPPPPL-PQPGDKSSWGRTRSLGG---------- 1292
G +GL + E G P P P L P P +S G+ + G
Sbjct: 657 GPGSADGL----CTIYETEG-PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711
Query: 1293 -----------------------LISAVGVGSTGGGCGGPG 1310
L+ A G+ GG GGPG
Sbjct: 712 ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 752
Score = 71.6 bits (174), Expect = 5e-12
Identities = 175/739 (23%), Positives = 234/739 (31%), Gaps = 138/739 (18%)
Query: 370 GAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSR 429
GAAA AA A + P SP P + + G G G K AGG
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI----- 65
Query: 430 SMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASAS 489
AT P S + +G S PP G P + PG S G AS +
Sbjct: 66 ----------GGATIPES-APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT 114
Query: 490 GSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPL 549
P G L S A P R G
Sbjct: 115 TRPGPLGQKGLR------------ISAEETVARGKATEAPKRSALSAG------------ 150
Query: 550 SHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSA 609
+ R SG + +R+ + T P P PS+ R + S ++
Sbjct: 151 -----ARRDTSGPTPGTPSPAMARRSRAAGTEV-GLPRPAPSARPRPPTEGPRKSVSSAS 204
Query: 610 GRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGS 669
+ P A P G ++ + RS SS+ TP ++ A SG S
Sbjct: 205 EH-----STTEPSPAARRRPSAGGGLQRPASRSLSSS---------ATPLSSPARSGP-S 249
Query: 670 CRSDDYMPMSPASVSAPK-----QILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASG 724
R P +PA S PK + P+ A P+ GP +P + + P S
Sbjct: 250 ARG---TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 725 GGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFF 784
+ S P S+ + L +L P + T PP
Sbjct: 307 SAPPSLQTLPSPPATP-------PSQATTSLGSPTLQATHSFLPSPPLSPLAT-PPPQAP 358
Query: 785 SAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQAT 844
A P PL+ P S P S L L+ +
Sbjct: 359 PALALP---PLQAPPSPPASPPLSPLATP-------------SPQAPNALAVHLLQAPFS 402
Query: 845 PGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSM 904
P PS A + P P PV PS PS P L V P+ P+ P M
Sbjct: 403 PPPSPPVQAPFSPPASP--PVSPSATPPSQAPPS--LAAPPLQVPPSP------PASPPM 452
Query: 905 HEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPG 964
PP P P +L+ P PP A ++ L + SP +S P
Sbjct: 453 SPSATPPPQAPP------PLAAPPLQLAKP-PPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 965 TSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSAS 1024
+ S S SPL+ +P P AP P ++P +PP P AS
Sbjct: 506 SPSASLPMSPLA-----------TPPPQAP-------------PVLAAPLLQVPPSPPAS 541
Query: 1025 PSSSLQPPPPPPAPG-ELYRLPPASAVATAQGPGAASSLS-SDTGDNGDYTEMAFGVAAT 1082
P +LQ P PP PG + P +A A GP S S S T D + +T
Sbjct: 542 P--TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 599
Query: 1083 PPQPIAAPPKPEAARVASP 1101
P + PE ASP
Sbjct: 600 PEELRGYDSGPEGGAAASP 618
Score = 70.1 bits (170), Expect = 1e-11
Identities = 143/569 (25%), Positives = 189/569 (33%), Gaps = 113/569 (19%)
Query: 841 PQATPGPSQAASAFGAGPTQPPHP-----VVPSPVRPSGGRPEGFLGQRGRAVR------ 889
P+A P + A G G PP V SP R SG G LGQ+G +
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134
Query: 890 -------PTRLSLEGLPSLPSMHEYPLPPEP------KSPGEYINIDFGEPGARLSPPA- 935
P R +L + P P P ++ G + + P AR PP
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194
Query: 936 -PPLLASAASSSSLLSASS-----PASSLGSGTPGTSSDSRQRSPLSDYMNLDFSS---- 985
P S+AS S S P++ G P + S S +PLS S+
Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 254
Query: 986 -----PKSPKPGA-----------PSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSL 1029
P PKP P +L L S ++P P PP PSA P SL
Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP--SL 312
Query: 1030 QPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPP----- 1084
Q P PPA PP+ A + P ++ S ATPP
Sbjct: 313 QTLPSPPA------TPPSQATTSLGSPTLQATHSF-------LPSPPLSPLATPPPQAPP 359
Query: 1085 ----QPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADP 1140
P+ APP P A + P S + S + LQA P P + + P
Sbjct: 360 ALALPPLQAPPSPPA---SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416
Query: 1141 QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEP 1200
S S T + PS A P + + + + S+ P P
Sbjct: 417 A------SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT------PPPQAPP 464
Query: 1201 PTS--PRQLQPAPPLAP--------QGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNG 1250
P + P QL PP AP Q P P G S PM + Q
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-- 522
Query: 1251 LNYIAIDVREEPGLPPQPQPP-PPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGP 1309
A V P L P PP P L P + G S+ G + + G P
Sbjct: 523 ----APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPP 573
Query: 1310 GPGALPPANTYASIDFLSHHLKEATIVKE 1338
P + P++T + D L+ H AT E
Sbjct: 574 PPPSRSPSSTLSGPD-LAGHSSSATSTPE 601
Score = 64.3 bits (155), Expect = 7e-10
Identities = 192/850 (22%), Positives = 290/850 (34%), Gaps = 155/850 (18%)
Query: 367 GDGGAAAGAAAAGARPVSVAGSP-------------LSPGPVRAPLSRSHTL-SGGCGGR 412
G GGA +A A P + P SPGPV +P S T G G +
Sbjct: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123
Query: 413 GSKVA---LLPAGGALQHSRSMSMPVA----HSPPAATSPGSLSSSSGHGSGSYPPPPGP 465
G +++ + G A + + ++ S P +P + +G+ P P
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183
Query: 466 HPPL-PHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESI 524
P P P GP + SS S ++ PS + S+ G L+ S RS + +
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPAS-RSLSSSAT 238
Query: 525 AETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQ 584
+ PAR G R R +Q +GL+ TP R+
Sbjct: 239 PLSSPARSGPS-----------------ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281
Query: 585 RPVPQ--PSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRS 642
P P S+S AT S SA P P++ P + P P + +
Sbjct: 282 DAAPALGPLSSS------PLATPSPSA----PPSPSAPPSLQTLPSPPATPPSQ-ATTSL 330
Query: 643 SSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAV 702
S L A ++P P + LA P +P +++ P + P + A+
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATP----------PPQAPPALALP-PLQAPPSPPASPPLS 379
Query: 703 PSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLP 762
P A P+ AP + A A SP S P + + P
Sbjct: 380 PLATPSPQAPNALAVHLLQA------PFSPPPSPPVQAPFS------------------P 415
Query: 763 NGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQ 822
VSPS + PP + L P P ++ P P
Sbjct: 416 PAS-PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP--------- 465
Query: 823 YVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLG 882
L + P L+ + PQA P+ A A P+ P +P PS P L
Sbjct: 466 --LAAPP----LQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 883 QRGRAVRPTRLS--LEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLA 940
P + L+ PS P+ P P +PG ++ L+P PP
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP--P 575
Query: 941 SAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVG 1000
+ S SS LS A G + TS+ R P+ GA + P
Sbjct: 576 PSRSPSSTLSGPDLA---GHSSSATSTPEELR-----------GYDSGPEGGAAASPPPD 621
Query: 1001 SLDGLLSPEASS--PYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGA 1058
+ P A S P PPL R +P + L P PP PG L + +GP +
Sbjct: 622 AELAACHPAAWSRGPAPPLAFR--GAPGAPL-PWPPATGPGSADGL---CTIYETEGPES 675
Query: 1059 ASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVE 1118
A+ + D G + G AA A+ P+ AR+ G + S+++ +
Sbjct: 676 ATP-APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRT 734
Query: 1119 AFLQASQPP--------------DPHRGAKVIRADPQGGRRRH----SSETFSSTTTVTP 1160
L A++ GA+ +D + GR E+ +S T+VT
Sbjct: 735 LLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTS 794
Query: 1161 VSPSFAHNPK 1170
SP +P+
Sbjct: 795 FSPDDVASPQ 804
Score = 53.1 bits (126), Expect = 2e-06
Identities = 143/586 (24%), Positives = 188/586 (32%), Gaps = 113/586 (19%)
Query: 303 RSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRR--SRTDSLAATP---PAAKCS 357
+S S +S S T P P ARR PS G ++R SR+ S +ATP PA
Sbjct: 198 KSVSSASEHSTTEPS--PAARRR-------PSAGGGLQRPASRSLSSSATPLSSPARSGP 248
Query: 358 SCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVA 417
S R + RP V P PLS S + +
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT-------PSPS 301
Query: 418 LLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPG------PHPPLPH 471
P+ A +++ P A P AT+ SL S + + S+ P P P P P
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATT--SLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 472 PLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPAR 531
L P Q P S AS SP SP A H P S +PP +
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLAT---------PSPQAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 532 DGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPS 591
P S VS A + SL P Q P P+
Sbjct: 411 -----------APFSPPAS------PPVSPSATPP-----SQAPPSLAAPPLQVPPSPPA 448
Query: 592 SASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADD 651
S + S + P A+ P P P+ + ++ S +
Sbjct: 449 SPPMSP--------SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500
Query: 652 GYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPA 711
G P +P A+L PMSP + P+ P AA VP + PA +
Sbjct: 501 GQAPFSPSASL--------------PMSPLATPPPQ---APPVLAAPLLQVPPSPPA--S 541
Query: 712 PTSAAGRTFPASGGGYKAS--------SPAESSPEDSGYMRMWCGSKLSMEHADGKLLPN 763
PT A R P G S +P P G L+ + P
Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 601
Query: 764 G-DYLNVSPSDAVTTGTPPDFFSAALHP-----GGEP---LRGVPGCCYSSLPRSYKAPY 814
+ P PPD AA HP G P RG PG + LP P
Sbjct: 602 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG---APLP---WPPA 655
Query: 815 TCGGDSDQYVLM---SSPVGRILEEERLEPQATPGPSQAASAFGAG 857
T G +D + P L+P +PG S +A GAG
Sbjct: 656 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 701
Score = 52.4 bits (124), Expect = 3e-06
Identities = 84/351 (23%), Positives = 122/351 (34%), Gaps = 77/351 (21%)
Query: 990 KPGAPSGHPVGSLDGLLSPE-ASSPYPPLPPRPSA------------------------- 1023
K GA + P GLL+P SP PP P P+A
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 1024 -SPSSSLQPPPP----PPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFG 1078
P S+ + P PPA G R PPA T+ GP ++ +S T G +
Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAK--NTSPGPVSSPGRASGTTRPGPLGQKGLR 126
Query: 1079 VAATPPQPIAAPPKPEAARVASPTSGVKR-------------LSLMEQVSGVEAFLQASQ 1125
++A + +A EA + ++ ++G +R ++ + +G E L
Sbjct: 127 ISA--EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL---- 180
Query: 1126 PPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVS---PSFAHNPKRHNSASVENVSL 1182
P P A+ R +G R+ SS + STT +P + PS +R S S+ + +
Sbjct: 181 -PRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 1183 RKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRE 1242
SS G G P P Q +P A + TP + SP+
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL--- 295
Query: 1243 TSAGFQNGLNYIAIDVREEPGLPPQPQPPP--PPLPQPGDKSSWGRTRSLG 1291
P PP P PP LP P T SLG
Sbjct: 296 ---------------ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331
Score = 33.1 bits (74), Expect = 1.8
Identities = 62/238 (26%), Positives = 80/238 (33%), Gaps = 38/238 (15%)
Query: 332 PPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGA----AAAGARPVSVAG 387
PP Q V + + +PPA+ R + G + +G A A P +
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578
Query: 388 SPLSP--GPVRAPLSRSHTLS------------GGCGGRGSKVALLPAGGALQHSRSMSM 433
SP S GP A S S T + GG A L A SR +
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638
Query: 434 PVAHSP--------PAATSPGSLSSS----SGHGSGSYPPPPGPHPPLPHPLHHGPGQRP 481
P+A P AT PGS G S P PG P P P G
Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698
Query: 482 SSGSASASGSPSDPGFMSLDEYGSSP-GDLRA-FCSHRSNTPESIAETPPARDGGGGG 537
+G+ ++S SP G P G L+A H + +A A G GGG
Sbjct: 699 GAGAGASSRSPKQA------RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 750
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 81.6 bits (200), Expect = 5e-15
Identities = 200/841 (23%), Positives = 280/841 (33%), Gaps = 163/841 (19%)
Query: 303 RSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRR--SRTDSLAATP---PAAKCS 357
+S S +S S T P P ARR PS G ++R SR+ S +ATP PA
Sbjct: 207 KSVSSASEHSTTEPS--PAARRR-------PSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 358 SCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKV- 416
S R + RP V P PLS S + G ++
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317
Query: 417 -----ALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSS---------SSGHGSGSYPPP 462
A P L S ++ P+ +PP+ ++P SL + S S + PP
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377
Query: 463 PGPH-----PPL--PHPLHHGPGQRPSS----GSASASGSPSDPGFMSLDEYGS-SPGDL 510
P PP+ PH L Q P S S A+ S P + + + SP
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437
Query: 511 RAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRG 570
+A + S + ++PP + PLS A+ L
Sbjct: 438 QASLTSPSRPASTPPDSPP---------------LQAPLSL----------PASPPLQTS 472
Query: 571 LRKRTYSLTTPARQRPVPQPSS-------ASLDEYTLMRATFSGSAGRLCPSCPASSPKV 623
L L++P P+ SS A L + S L P + P
Sbjct: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS---LAPPSLQTPPAS 529
Query: 624 AYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASV 683
P E+ + +++S+ L P P + + P +P+S+
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP--PETPSSI 587
Query: 684 SAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYM 743
+ P P A A A+ P G P+P + T P A P ++ P
Sbjct: 588 ATP-----PPQAPPALASPPLQGL--PSPPLSPLATPPPQAPPXLALPPLQAPPSPPA-- 638
Query: 744 RMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCY 803
LS PN +++ + +PP A P P
Sbjct: 639 ----SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP--VQAPFSPPASPPVSPSATPP 692
Query: 804 SSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQ-PP 862
S P S AP V S P + P ATP P QA A P Q PP
Sbjct: 693 SQAPPSLAAP-------PLQVPPSPPAS-----PPMSPSATP-PPQAPPPLAAPPLQVPP 739
Query: 863 HPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINI 922
P P+ PS P P +P + P P SP + +
Sbjct: 740 SPPASPPMSPSATPP---------------------PRVPPLLAAPPLQVPPSPPASLPM 778
Query: 923 DFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLD 982
P A+ P APP LA+ L + SP +S P + S S SPL+
Sbjct: 779 S---PLAKPPPQAPPALATPP----LQALPSPPASFPGQAPFSPSASLPMSPLA------ 825
Query: 983 FSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPG-EL 1041
+P P AP P ++P +PP P ASP +LQ P PP PG +
Sbjct: 826 -----TPPPQAP-------------PVLAAPLLQVPPSPPASP--TLQAPRRPPTPGPDT 865
Query: 1042 YRLPPASAVATAQGPGAASSLS-SDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVAS 1100
P +A A GP S S S T D + +TP + PE AS
Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Query: 1101 P 1101
P
Sbjct: 926 P 926
Score = 78.6 bits (192), Expect = 4e-14
Identities = 217/864 (25%), Positives = 284/864 (32%), Gaps = 139/864 (16%)
Query: 321 GARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAAGA 380
GARR + RRSR P S R R +EG + + A+
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-APSARPRPPTEGPRKSVSSASEHST 217
Query: 381 RPVSVAGS--PLSPGPVRAPLSRSHTLSG---------GCGGRGSKVALLPAGGALQHSR 429
S A P + G ++ P SRS + S G RG+ A
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 430 SMSMPVAHSPP---AATSPGSLSSS-------SGHGSGSYPPPPGPHPPLPHPLHHGPGQ 479
P +PP AA + G LSSS SG + PPP PLP L P
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL--PPSP 335
Query: 480 RPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEF 539
++ A SPS P SL S P TP S + PP
Sbjct: 336 PLATPLPLAPPSPSAP--PSLQTLPSPPA-----------TPPS--QAPP---------- 370
Query: 540 YGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYT 599
+M P S + + +SLT+P+ Q P P P + S +
Sbjct: 371 ----SMTTPPMQAPPSLQTIPPIQV----------PHSLTSPSLQAP-PSPLALS----S 411
Query: 600 LMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPG 659
L T GS P+ A+ + P S S S P+
Sbjct: 412 LQATTSLGS-----PTLQATHSFLTMSPRQTQ------ASLTSPSRPASTPPDSPPLQAP 460
Query: 660 AALAGSGS-GSCRSDDYMPMSPASVSAPKQIL------QPRAAAAAAAAVPSAGPAGPAP 712
+L S + S P+S P Q L P+A ++ P + AP
Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
Query: 713 TSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPS 772
S +T PAS + P E+ P + + L+ H + P L PS
Sbjct: 521 PSL--QTPPAS----LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574
Query: 773 DAVT--------TGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
T TPP AL PL+G+P S L
Sbjct: 575 PLTTPPPETPSSIATPPPQAPPAL--ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632
Query: 825 LMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQ-----PPHPVVPSPVRPSGGRPEG 879
S P L P ATP P QA +A Q PP P V +P P P
Sbjct: 633 PPSPPA-----SPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP-- 684
Query: 880 FLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPP--APP 937
V P+ P PS+ PL P P P + PP APP
Sbjct: 685 --------VSPSATPPSQAP--PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 938 LLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGH 997
L + +S SP+++ P + + P S +L S P P AP
Sbjct: 735 LQVPPSPPAS--PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 998 PVGSLDGLLSPEASSPYPPLPPRPSAS-PSSSLQPPPPPPAP---GELYRLPPA-SAVAT 1052
L L SP AS P P PSAS P S L PPP P L ++PP+ A T
Sbjct: 793 ATPPLQALPSPPASFP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 1053 AQGPGAASSLSSDTGDNGDYTEMAFGVAATPP---QPIAAPPKPEAARVASPTSGVKRLS 1109
Q P + DT +G +A PP P + P+ A +S +
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE-E 910
Query: 1110 LMEQVSGVEAFLQASQPPDPHRGA 1133
L SG E AS PPD A
Sbjct: 911 LRGYDSGPEGGAAASPPPDAELAA 934
Score = 76.6 bits (187), Expect = 1e-13
Identities = 243/1084 (22%), Positives = 355/1084 (32%), Gaps = 213/1084 (19%)
Query: 349 ATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGG 408
AT P + + R+A A+ A+G + SPGPV +P S T G
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 409 -CGGRGSKVAL---LPAGGALQHSRSMSMPVAH----SPPAATSPGSLSSSSGHGSGSYP 460
G +G +++ + G A + + ++ S P +P + +G+
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 461 PPPGPHPPL-PHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSN 519
P P P P P GP + SS S ++ PS + S+ G L+ S RS
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPAS-RSL 242
Query: 520 TPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLT 579
+ + + PAR G R R +Q +GL+
Sbjct: 243 SSSATPLSSPARSGPSA-----------------RGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 580 TPARQ------------------------RPVPQPSSASLD-EYTLMRATFSGSAGRLCP 614
TP R+ RPVP P +A+ TL + + L P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
Query: 615 SCPASSPKVAYHPYP-----------------------EDYGDIEIGSHRSSSSNLGADD 651
P++ P + P P + I++ H +S +L A
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV-PHSLTSPSLQAPP 404
Query: 652 GYMPMTPGAALAGSGSGSCRSD-DYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGP 710
+ ++ A GS + ++ ++ MSP A + + A+ P P
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL------TSPSRPASTPPDSPPLQ 458
Query: 711 APTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVS 770
AP S PAS + SPA S + H+ L + L +
Sbjct: 459 APLS-----LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS---LIMP 510
Query: 771 PSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPV 830
P + ++ PP + PL +P L ++ AP T P+
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL-QTASAPLTTPHLETPPCPAPCPL 569
Query: 831 GRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAV-- 888
+ P TP P + S+ P Q P P + SP P G P L
Sbjct: 570 -----QAPPSPLTTP-PPETPSSIATPPPQAP-PALASP--PLQGLPSPPLSPLATPPPQ 620
Query: 889 RPTRLSLEGLPSLPSMHEYP-----LPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAA 943
P L+L L + PS P P P++P P + PP+PP+ A +
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS--PPPSPPVQAPFS 678
Query: 944 SSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLD 1003
+S SP+++ S P + + + P S + S +P P AP L
Sbjct: 679 PPAS--PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 1004 GLLSPEASSPYPPL---PPR-PSASPSSSLQPPPPPPAP---GELYRLPPASAVATAQGP 1056
SP AS P P PPR P + LQ PP PPA L + PP + A A P
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796
Query: 1057 GAA--SSLSSDTGDNGDYTEMAFGVAAT-PPQPIAAPPKPEAARVASPTSGVKRLSLMEQ 1113
A S +S G + F +A+ P P+A PP +A+P L +
Sbjct: 797 LQALPSPPASFPG------QAPFSPSASLPMSPLATPPPQAPPVLAAPL-----LQVPPS 845
Query: 1114 VSGVEAFLQASQPPDPHRGAKV--------IRADPQGGRRRHSSETFSSTTTVTPVSPSF 1165
+PP P V + P R S T S P
Sbjct: 846 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG--------PDL 897
Query: 1166 AHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDE-----PPTSPRQLQPAPPLAPQGRPW 1220
A + S E EGG P E P R PAPPLA +G P
Sbjct: 898 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG--PAPPLAFRGAPG 955
Query: 1221 TPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPL-PQPG 1279
P P T G +GL + E G P P P L P P
Sbjct: 956 AP--------------LPWPPATGPGSADGL----CTIYETEG-PESATPAPGALDPGPS 996
Query: 1280 DKSSWGRTRSLGG---------------------------------LISAVGVGSTGGGC 1306
+S G+ + G L+ A G+ GG
Sbjct: 997 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 1056
Query: 1307 GGPG 1310
GGPG
Sbjct: 1057 GGPG 1060
Score = 72.4 bits (176), Expect = 3e-12
Identities = 231/1000 (23%), Positives = 336/1000 (33%), Gaps = 132/1000 (13%)
Query: 370 GAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSR 429
GAAA AA A + P SP P + + G G G K AGG
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI----- 65
Query: 430 SMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASAS 489
+ S P A P + +S S PP G P + PG S G AS +
Sbjct: 66 -GGATIPESAPRA-GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 490 GSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPL 549
P G L S A P R G
Sbjct: 124 TRPGPLGQKGLR------------ISAEETVARGKATEAPKRSALSAG------------ 159
Query: 550 SHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSA 609
+ R SG + +R+ + T P P PS+ R + S ++
Sbjct: 160 -----ARRDTSGPTPGTPSPAMARRSRAAGTEV-GLPRPAPSARPRPPTEGPRKSVSSAS 213
Query: 610 GRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGS 669
+ P A P G ++ + RS SS+ P++ A S G+
Sbjct: 214 EH-----STTEPSPAARRRPSAGGGLQRPASRSLSSSA------TPLSSPARSGPSARGT 262
Query: 670 CRSDDYMPM-SPASVSA--PKQILQPRAAAAAAAAVPSAGP-AGPAPTSAAGRTFPASGG 725
R+ + P + A P Q+ PR AA A S+ P A P+P+ R P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD- 321
Query: 726 GYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFS 785
A++P ++ S + + L + P+ L SP + PP +
Sbjct: 322 --NAATPLPATLPPSPPL----ATPLPLAPPSPSAPPSLQTL-PSPPATPPSQAPPSMTT 374
Query: 786 AALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEP---- 841
+ L+ +P +P S +P + L S L L+
Sbjct: 375 PPMQ-APPSLQTIPPI---QVPHSLTSP-SLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 842 -QATPGPSQAASAFGAGP--TQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRP--TRLSLE 896
+P +QA+ + P T P P + +P+ P AV P + L++
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP--LQTSLSPAVSPLSSPLTIH 487
Query: 897 GLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPA----------PPL--LASAAS 944
L +L S+ + P++P + + E + L+PP+ PPL L S A
Sbjct: 488 PLQALSSLASH----SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA- 542
Query: 945 SSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKS---PKPGAPSGHPVGS 1001
L +AS+P ++ TP + ++P S +P S P P AP
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 1002 LDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASS 1061
L GL SP S P P P LQ PP PPA PP S +AT P A ++
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS------PPLSPLAT-PSPQAPNA 655
Query: 1062 LSSDTGDNGDYTEMAFGVAATPP--QPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEA 1119
L+ + F +PP P + P P + A+P S SL V
Sbjct: 656 LAV------HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP-SLAAPPLQVPP 708
Query: 1120 FLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVEN 1179
AS P P P + S P+SPS P+ +
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAA---PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 1180 VSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPM 1239
+ + S + + P PP +P L PPL Q P P G S PM
Sbjct: 766 LQVPPSPPASLPMSP-LAKPPPQAPPAL-ATPPL--QALPSPPASFPGQAPFSPSASLPM 821
Query: 1240 RRETSAGFQNGLNYIAIDVREEPGLPPQPQPP-PPPLPQPGDKSSWGRTRSLGGLISAVG 1298
+ Q A V P L P PP P L P + G S+ G +
Sbjct: 822 SPLATPPPQ------APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 875
Query: 1299 VGSTGGGCGGPGPGALPPANTYASIDFLSHHLKEATIVKE 1338
+ G P P + P++T + D L+ H AT E
Sbjct: 876 LAP-----GPPPPPSRSPSSTLSGPD-LAGHSSSATSTPE 909
Score = 51.6 bits (122), Expect = 5e-06
Identities = 80/346 (23%), Positives = 123/346 (35%), Gaps = 71/346 (20%)
Query: 990 KPGAPSGHPVGSLDGLLSPE-ASSPYPPLPPRPSA------------------------- 1023
K GA + P GLL+P SP PP P P+A
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 1024 --------------SPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDN 1069
+ +SS P PPA G R PPA T+ GP ++ +S T
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK--NTSPGPVSSPGRASGTTRP 126
Query: 1070 GDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKR-------------LSLMEQVSG 1116
G + ++A + +A EA + ++ ++G +R ++ + +G
Sbjct: 127 GPLGQKGLRISA--EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 1117 VEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVS---PSFAHNPKRHN 1173
E L P P A+ R +G R+ SS + STT +P + PS +R
Sbjct: 185 TEVGL-----PRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 1174 SASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPG 1233
S S+ + + SS G G P P Q +P A + TP +
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 1234 SGGSPMRRETSAGFQNGLNYIAIDVREEPGLP-PQPQPPPPPLPQP 1278
SP+ + +G + + + P P PP PPL P
Sbjct: 299 LSSSPLATPSPSGTKAR----PVPPPDNAATPLPATLPPSPPLATP 340
Score = 33.1 bits (74), Expect = 1.8
Identities = 62/238 (26%), Positives = 80/238 (33%), Gaps = 38/238 (15%)
Query: 332 PPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGA----AAAGARPVSVAG 387
PP Q V + + +PPA+ R + G + +G A A P +
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886
Query: 388 SPLSP--GPVRAPLSRSHTLS------------GGCGGRGSKVALLPAGGALQHSRSMSM 433
SP S GP A S S T + GG A L A SR +
Sbjct: 887 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946
Query: 434 PVAHSP--------PAATSPGSLSSS----SGHGSGSYPPPPGPHPPLPHPLHHGPGQRP 481
P+A P AT PGS G S P PG P P P G
Sbjct: 947 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 1006
Query: 482 SSGSASASGSPSDPGFMSLDEYGSSP-GDLRA-FCSHRSNTPESIAETPPARDGGGGG 537
+G+ ++S SP G P G L+A H + +A A G GGG
Sbjct: 1007 GAGAGASSRSPKQA------RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 1058
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 80.5 bits (197), Expect = 1e-14
Identities = 179/749 (23%), Positives = 246/749 (32%), Gaps = 119/749 (15%)
Query: 370 GAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSR 429
GAAA AA A + P SP P + + G G G K AGG
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI----- 65
Query: 430 SMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASAS 489
+ S P A P + +S S PP G P + PG S G AS +
Sbjct: 66 -GGATIPESAPRA-GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 490 GSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPL 549
P G L S A P R G
Sbjct: 124 TRPGPLGQKGLR------------ISAEETVARGKATEAPKRSALSAG------------ 159
Query: 550 SHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSA 609
+ R SG + +R+ + T P P PS+ R + S ++
Sbjct: 160 -----ARRDTSGPTPGTPSPAMARRSRAAGTEV-GLPRPAPSARPRPPTEGPRKSVSSAS 213
Query: 610 GRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGS 669
+ P A P G ++ + RS SS+ P++ A S G+
Sbjct: 214 EH-----STTEPSPAARRRPSAGGGLQRPASRSLSSSA------TPLSSPARSGPSARGT 262
Query: 670 CRSDDYMPM-SPASVSA--PKQILQPRAAAAAAAAVPSAGP-AGPAPTSAAGRTFPASGG 725
R+ + P + A P Q+ PR AA A S+ P A P+P++A P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP---- 318
Query: 726 GYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFS 785
P + S + + L + P+ L P+ TPP +
Sbjct: 319 ------PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA------TPPSQAT 366
Query: 786 AALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILE---EERLEPQ 842
+L G L+ +S LP +P L P+ L P
Sbjct: 367 TSL--GSPTLQAT----HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Query: 843 ATPGPSQAASAFGAGPTQ-----PPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEG 897
ATP P QA +A Q PP P V +P P P V P+
Sbjct: 421 ATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP----------VSPSATPPSQ 469
Query: 898 LPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPP--APPL-LASAASSSSLLSASSP 954
P PS+ PL P P P + PP APPL LA + A+ P
Sbjct: 470 AP--PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527
Query: 955 ASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPY 1014
+L P + ++P S +L S +P P AP P ++P
Sbjct: 528 LQAL----PSPPASFPGQAPFSPSASLPMSPLATPPPQAP-------------PVLAAPL 570
Query: 1015 PPLPPRPSASPSSSLQPPPPPPAPG-ELYRLPPASAVATAQGPGAASSLS-SDTGDNGDY 1072
+PP P ASP +LQ P PP PG + P +A A GP S S S T D
Sbjct: 571 LQVPPSPPASP--TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 628
Query: 1073 TEMAFGVAATPPQPIAAPPKPEAARVASP 1101
+ +TP + PE ASP
Sbjct: 629 AGHSSSATSTPEELRGYDSGPEGGAAASP 657
Score = 75.5 bits (184), Expect = 3e-13
Identities = 168/701 (23%), Positives = 226/701 (32%), Gaps = 153/701 (21%)
Query: 678 MSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPT---------SAAGRTFPASGGGYK 728
M+ S +A ++ PR A +A P+ GP + S A R P++GGG +
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 729 ASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAAL 788
PA S S + LS G PS GTP A
Sbjct: 236 R--PASRSLSSSA-------TPLSSPARSG------------PS---ARGTP----RAPA 267
Query: 789 HPGGEPLRGVPGCCYSSL--PRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPG 846
HP +G+ + PR AP G S + SP + + ATP
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAP-ALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 847 PSQAASAFGAG-PTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLE-GLPSLPSM 904
S P PP P P ++ P A P++ + G P+L +
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP---------ATPPSQATTSLGSPTLQAT 377
Query: 905 HEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLA----SAASSSSLLSASSPASSLGS 960
H + LP P SP A P APP LA A S SP ++
Sbjct: 378 HSF-LPSPPLSPL-----------ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 425
Query: 961 GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPR 1020
P + ++P S + +P SP P +P P + P ++P +PP
Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPS 484
Query: 1021 PSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASS--LSSDTGDNGDYTEMA-F 1077
P ASP S PPP AP L P A Q P A ++ L + + A F
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 1078 GVAAT-PPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKV- 1135
+A+ P P+A PP +A+P L + +PP P V
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPL-----LQVPPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 1136 -------IRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEG 1188
+ P R S T S P A + S E EG
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLS--------GPDLAGHSSSATSTPEELRGYDSGPEG 651
Query: 1189 GVGVGPGGGDE-----PPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRET 1243
G P E P R PAPPLA +G P P P T
Sbjct: 652 GAAASPPPDAELAACHPAAWSR--GPAPPLAFRGAPGAP--------------LPWPPAT 695
Query: 1244 SAGFQNGLNYIAIDVREEPGLPPQPQPPPPPL-PQPGDKSSWGRTRSLGG---------- 1292
G +GL + E G P P P L P P +S G+ + G
Sbjct: 696 GPGSADGL----CTIYETEG-PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750
Query: 1293 -----------------------LISAVGVGSTGGGCGGPG 1310
L+ A G+ GG GGPG
Sbjct: 751 ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 791
Score = 63.2 bits (152), Expect = 2e-09
Identities = 189/856 (22%), Positives = 285/856 (33%), Gaps = 114/856 (13%)
Query: 349 ATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTL-SG 407
AT P + + R+A A+ A+G + SPGPV +P S T G
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 408 GCGGRGSKVA---LLPAGGALQHSRSMSMPVA----HSPPAATSPGSLSSSSGHGSGSYP 460
G +G +++ + G A + + ++ S P +P + +G+
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 461 PPPGPHPPL-PHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSN 519
P P P P P GP + SS S ++ PS + S+ G L+ S RS
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPAS-RSL 242
Query: 520 TPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLT 579
+ + + PAR G R R +Q +GL+
Sbjct: 243 SSSATPLSSPARSGPS-----------------ARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 580 TPARQRPVPQ--PSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEI 637
TP R+ P P S+S A A P+ P SS P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP--- 342
Query: 638 GSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCR-SDDYMPMSPASVSAPKQILQPRAAA 696
S+ +L P A GS + + + ++P P S A P A A
Sbjct: 343 -PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 697 AAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHA 756
P + PA P + A + A A SP S ++ S
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP-- 459
Query: 757 DGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTC 816
VSPS + PP + L P P ++ P P
Sbjct: 460 ------------VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP--- 504
Query: 817 GGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGR 876
L + P L+ + PQA P+ A A P+ P +P PS
Sbjct: 505 --------LAAPP----LQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASL 550
Query: 877 PEGFLGQRGRAVRPTRLS--LEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPP 934
P L P + L+ PS P+ P P +PG ++ L+P
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 935 APPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAP 994
PP + S SS LS A G + TS+ R P+ GA
Sbjct: 611 PPP--PPSRSPSSTLSGPDLA---GHSSSATSTPEELR-----------GYDSGPEGGAA 654
Query: 995 SGHPVGSLDGLLSPEASS--PYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVAT 1052
+ P + P A S P PPL R +P + L P PP PG L +
Sbjct: 655 ASPPPDAELAACHPAAWSRGPAPPLAFR--GAPGAPL-PWPPATGPGSADGL---CTIYE 708
Query: 1053 AQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLME 1112
+GP +A+ + D G + G AA A+ P+ AR+ G + S+++
Sbjct: 709 TEGPESATP-APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 767
Query: 1113 QVSGVEAFLQASQPP--------------DPHRGAKVIRADPQGGRRRH----SSETFSS 1154
+ L A++ GA+ +D + GR E+ +S
Sbjct: 768 HLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRAS 827
Query: 1155 TTTVTPVSPSFAHNPK 1170
T+VT SP +P+
Sbjct: 828 ITSVTSFSPDDVASPQ 843
Score = 58.2 bits (139), Expect = 5e-08
Identities = 114/464 (24%), Positives = 160/464 (34%), Gaps = 81/464 (17%)
Query: 857 GPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSP 916
G +PP PV P+ +R G G +G++ A R + +P P +S
Sbjct: 31 GSPRPPPPVTPAALRVLGA--AGAVGRKPLAERAGGIGGATIP-----ESAPRAGPTRSA 83
Query: 917 GEYINIDFGEPGA----RLSPPAPPLLASAASSSSLLSASSPASSLG----------SGT 962
G P A +PPA SS S ++ LG +
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 963 PGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPS------GHPVGSLDGLLSPEASS-PYP 1015
G ++++ +RS LS D S P PG PS G+ GL P S+ P P
Sbjct: 144 RGKATEAPKRSALSAGARRDTS---GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200
Query: 1016 PLP-PR---PSASPSSSLQPPPP----PPAPGELYRLPPASAVATAQGPGAASSLSSDTG 1067
P PR SAS S+ +P P P A G L R PAS ++ +S S
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR--PASRSLSSSATPLSSPARSGPS 258
Query: 1068 DNGDYTEMAF-------GVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAF 1120
G A G+ A P P PP+ +AA P S S A
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRP-PQVTPPRKDAAPALGPLS-----SSPLATPSPSAA 312
Query: 1121 LQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENV 1180
LQ+ PP + A P HSS T P++P P + ++ +
Sbjct: 313 LQSQAPP-------TLPATP------HSSSLTCQLATPLPLAPPSPSAPP--SLQTLPSP 357
Query: 1181 SLRKSSEGGVGVGPGGGDEPPT--SPRQLQPAPPLAPQGRPWTPGQPG----GLVGCPGS 1234
S+ +G PT + P+PPL+P P P L P
Sbjct: 358 PATPPSQATTSLG------SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 411
Query: 1235 GGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQP 1278
SP + N +A+ + + P PP P P P
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455
Score = 51.6 bits (122), Expect = 5e-06
Identities = 82/328 (25%), Positives = 119/328 (36%), Gaps = 44/328 (13%)
Query: 994 PSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATA 1053
P G + G PE++ P P SA +SS P PPA G R PPA T+
Sbjct: 57 PLAERAGGIGGATIPESA---PRAGPTRSAG-TSSRNPASRPPASGRGERAPPAK--NTS 110
Query: 1054 QGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKR------ 1107
GP ++ +S T G + ++A + +A EA + ++ ++G +R
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISA--EETVARGKATEAPKRSALSAGARRDTSGPT 168
Query: 1108 -------LSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTP 1160
++ + +G E L P P A+ R +G R+ SS + STT +P
Sbjct: 169 PGTPSPAMARRSRAAGTEVGL-----PRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSP 222
Query: 1161 VS---PSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQP------AP 1211
+ PS +R S S+ + + SS G G P P Q +P P
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 1212 PLAPQGRPWTPGQPGGLVGCPGSGGSP------MRRETSAGFQNGLNYIAIDVREEPGLP 1265
P R G L P + SP T + + P P
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
Query: 1266 PQPQPPP--PPLPQPGDKSSWGRTRSLG 1291
P P PP LP P T SLG
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLG 370
Score = 48.9 bits (115), Expect = 3e-05
Identities = 148/614 (24%), Positives = 191/614 (31%), Gaps = 139/614 (22%)
Query: 303 RSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRR--SRTDSLAATP---PAAKCS 357
+S S +S S T P P ARR PS G ++R SR+ S +ATP PA
Sbjct: 207 KSVSSASEHSTTEPS--PAARRR-------PSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 358 SCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSH--TLSGGCGGRGSK 415
S R + RP V P PLS S T S +
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQA 317
Query: 416 VALLPAGGALQHSRSMSMPVAH-------------------SPPAA------TSPGSLSS 450
LPA HS S++ +A SPPA TS GS +
Sbjct: 318 PPTLPA---TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374
Query: 451 SSGHGSGSYPP-------PPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEY 503
+ H PP PP P L P P P+S S +P
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP----------- 423
Query: 504 GSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDA 563
SP A H P S +PP + P S VS A
Sbjct: 424 --SPQAPNALAVHLLQAPFSPPPSPPVQ-----------APFSPPAS------PPVSPSA 464
Query: 564 AQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKV 623
+ SL P Q P P+S + S + P A+ P
Sbjct: 465 TPP-----SQAPPSLAAPPLQVPPSPPASPPMSP--------SATPPPQAPPPLAAPPLQ 511
Query: 624 AYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASV 683
P P+ + ++ S + G P +P A+L PMSP +
Sbjct: 512 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--------------PMSPLAT 557
Query: 684 SAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKAS--------SPAES 735
P+ P AA VP + PA +PT A R P G S +P
Sbjct: 558 PPPQ---APPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 736 SPEDSGYMRMWCGSKLSMEHADGKLLPNG-DYLNVSPSDAVTTGTPPDFFSAALHP---- 790
P G L+ + P + P PPD AA HP
Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672
Query: 791 -GGEP---LRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLM---SSPVGRILEEERLEPQA 843
G P RG PG + LP P T G +D + P L+P
Sbjct: 673 RGPAPPLAFRGAPG---APLP---WPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726
Query: 844 TPGPSQAASAFGAG 857
+PG S +A GAG
Sbjct: 727 SPGTSGGKAAAGAG 740
Score = 33.1 bits (74), Expect = 1.8
Identities = 62/238 (26%), Positives = 80/238 (33%), Gaps = 38/238 (15%)
Query: 332 PPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGA----AAAGARPVSVAG 387
PP Q V + + +PPA+ R + G + +G A A P +
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617
Query: 388 SPLSP--GPVRAPLSRSHTLS------------GGCGGRGSKVALLPAGGALQHSRSMSM 433
SP S GP A S S T + GG A L A SR +
Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 677
Query: 434 PVAHSP--------PAATSPGSLSSS----SGHGSGSYPPPPGPHPPLPHPLHHGPGQRP 481
P+A P AT PGS G S P PG P P P G
Sbjct: 678 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737
Query: 482 SSGSASASGSPSDPGFMSLDEYGSSP-GDLRA-FCSHRSNTPESIAETPPARDGGGGG 537
+G+ ++S SP G P G L+A H + +A A G GGG
Sbjct: 738 GAGAGASSRSPKQA------RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 789
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 79.7 bits (195), Expect = 2e-14
Identities = 209/988 (21%), Positives = 304/988 (30%), Gaps = 225/988 (22%)
Query: 420 PAGGALQHSRSMSMPVAHSPPAATS-------PGSLSSSSGHGSGSYPP-PPGPHPPLPH 471
PA G L + + + +P +S G + +G G PP PGP P P
Sbjct: 178 PANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPP 237
Query: 472 PLHHGPGQ---RPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETP 528
P H P Q SS +A+A+ S P + G++PG P
Sbjct: 238 P-RHLPTQFNLLASSSAAAAAAEQSSPQLYNFS--GAAPGP-----------------PP 277
Query: 529 PARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVP 588
P R D + H Y+R + + Q P P
Sbjct: 278 PER---------ALPRQDTVIKH----YQRPA---------------------SAQPPPP 303
Query: 589 QPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLG 648
P + +L Y ++ R +C SP P P + G +++ G
Sbjct: 304 PPPAHALQHYLSCGGSYPSMGHRANLAC---SPLGGGEPSPGAGEPSKAGPSGATAGASG 360
Query: 649 ADDGYMPMTPGAALAGSGSGSCRSDDYMP-----MSPASVSAPKQILQPRAAAAAAAAVP 703
G P G AG G G R P +A P + A
Sbjct: 361 RATG--PEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQ 418
Query: 704 SAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPN 763
S G GPA A G+ A G G +A SP + L A G+
Sbjct: 419 SLG--GPAAAYATGKASGAGGAGGQAYSPGQP-------------QGLLGPQAYGQGFGG 463
Query: 764 GDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQY 823
G ++S + + + G P P G P G+ C +SY G Y
Sbjct: 464 GQAQDLSKAPSYSGGPPQP-------PSGPPPPGLATC------QSYSPDQLQG---QLY 507
Query: 824 VLMSSPVGRILEEERLEPQATPGPSQA----------------ASAFGAGPTQPPHPVVP 867
+ P + P A+P S + +S G G P H + P
Sbjct: 508 GVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRP 567
Query: 868 SPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSL--PSMHEYPLPP---EPKSPGEYINI 922
P+ GRP G +G G + L P L P Y + K G +
Sbjct: 568 LQSPPATGRPPG-VGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLA 626
Query: 923 DFGEPGAR------------LSPPAPPLLASAASSSSLLSASSPASSLG-----SGTPGT 965
G P A L P+PP + A A+ + LG G PGT
Sbjct: 627 GPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGT 686
Query: 966 SSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVG----------------SLDGLLSPE 1009
+ + P ++ + S GA + +G + +GL +
Sbjct: 687 PYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSV 746
Query: 1010 A--------------SSPYPPLPPRPSASPSSS--------------LQPPPPPPAPGEL 1041
SP PP P S P+ L PPPP P L
Sbjct: 747 VHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVL 806
Query: 1042 YRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARV--- 1098
P S A+ G + D A PP P PP P ++
Sbjct: 807 SHAPSPSPSASKVGVHLLEPATRDG-------------APQPPPPPPPPPPPMPLQLEAH 853
Query: 1099 --------ASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVI------RADPQGGR 1144
A+P+ ++ ++ ++ L A +P P G + DP G
Sbjct: 854 LRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAY 913
Query: 1145 RRHSSETFSSTTTVTPVS----PSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEP 1200
R S + + V S S + +R ++E + +++ GP +
Sbjct: 914 RSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGD 973
Query: 1201 PTSPRQLQPAPPLAPQGRPWTPGQPGGL-VGCPGSGGSPMRRETSAGFQNGLNYIAIDVR 1259
P + P PP P+ PG+ G PG G P + N I
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033
Query: 1260 EEPGLPPQPQPPPPPLPQPGDKSSWGRT 1287
PP P PPPPP P P + G T
Sbjct: 1034 PHQAAPPPPPPPPPP-PAPASEPKGGLT 1060
Score = 68.2 bits (165), Expect = 5e-11
Identities = 190/876 (21%), Positives = 272/876 (31%), Gaps = 201/876 (22%)
Query: 331 LPPSQTGLVRRSRTDSLAATPPAAKCS------SCRVRTASEGDGGAAAGAAAAGARPVS 384
LP T + R S PP SC S G A + G P
Sbjct: 282 LPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSP 341
Query: 385 VAGSPLSPGPVRAPLSRSHTLSG----GCGGRGSKVALLPAGGALQHSRSMSMPVAHSPP 440
AG P GP A S +G G GG G GG + P+ SP
Sbjct: 342 GAGEPSKAGPSGATAGASGRATGPEAAGGGGAGG------GGGGYR-------PIIQSPG 388
Query: 441 AATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSL 500
T G +++G G+ PPP P L GP ++G AS +G +
Sbjct: 389 YKTGKGGYGAAAG-GATRPPPPRSTATPKCQSL-GGPAAAYATGKASGAGGAGGQAY--- 443
Query: 501 DEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVS 560
SPG P+ + G GGG+
Sbjct: 444 -----SPGQ-----------PQGLLGPQAYGQGFGGGQ---------------------- 465
Query: 561 GDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYT--LMRATFSGSAGRLCPSCPA 618
AQDL + +YS P P P A+ Y+ ++ G G P A
Sbjct: 466 ---AQDLSKA---PSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAA 519
Query: 619 SSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPM 678
S + ++S +L G+ P AL+G G G S +
Sbjct: 520 HSQGLP-----------------TASPSLSYSTGHSP-----ALSGHGGGWGPSS----L 553
Query: 679 SPASVSAPKQILQPRAAAAAAAAVPSAGPAG------PAPTSAAGRTFPASGGGYKASSP 732
++P I++P + A P G G + ++A P G Y A +
Sbjct: 554 GGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAG 613
Query: 733 AESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGT-----PPDFFSAA 787
D + G + D + L +L +PS T+G A+
Sbjct: 614 GYKGKGDGSELLAGPGGPPAERTEDEEFLI--QHLLQAPSPPRTSGADGLVGEDGAADAS 671
Query: 788 LHPGGE-PLRGVPGCCYSSL---PRSYKAP----YTCGGDSDQYVLMSSPVGRILEEERL 839
GG G PG Y P+ Y + D + +GR+ E+++
Sbjct: 672 KGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKG 731
Query: 840 EPQATPGPSQAASA---FGAGPTQ---------PPHPVVPSPVRPSGGRPEGFLGQRGRA 887
+ P A++ +GAG + PP P +P+ P G L + G
Sbjct: 732 PERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPT---PHGLLLEAGGP 788
Query: 888 VRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGAR---------LSPPAPPL 938
P L LPS+ + P P + + EP R PP PP+
Sbjct: 789 DLPLVLPPPPPQLLPSVLSH--APSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM 846
Query: 939 ------------LASAASS---------------SSLLSASSPASSLGSGTPGTSSDSRQ 971
L AA S LL A P T +S
Sbjct: 847 PLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEG 906
Query: 972 RSPLSDYMNLDFSSPKSPKPGAPSGHPVGSL---DGLLSPEASSPYPPL----------- 1017
+ P Y + SP+ K AP P+ S+ D LL E S +P +
Sbjct: 907 KDPAGAYRS---PSPQGTK--APRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD 961
Query: 1018 -----PPRPSASPSSSLQPPPPPPA--PGELYRLPPASAVATAQGPGAASSLSSDTGDNG 1070
PP P + PPP PPA P Y P ++ A + PG +
Sbjct: 962 YGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPY-CPGRASGAGPETPGLGLDPNKPPELPS 1020
Query: 1071 DYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVK 1106
G+ + P A PP P +P S K
Sbjct: 1021 TVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPK 1056
Score = 67.4 bits (163), Expect = 9e-11
Identities = 159/620 (25%), Positives = 199/620 (32%), Gaps = 140/620 (22%)
Query: 785 SAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSP-----VGRILEEERL 839
SA HP R P SL +P G S VL P V L ERL
Sbjct: 149 SAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERL 208
Query: 840 EPQATPGPSQAASAFGAGPTQPP--HPVVPSPVRPSGGRPEGF--LGQRGRAVRPTRLSL 895
GP+ G GP Q P P P P P P F L A S
Sbjct: 209 AGGGVLGPA------GLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSS 262
Query: 896 EGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPA 955
L + P PPE P + I + A PP PP A A S P+
Sbjct: 263 PQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPS 322
Query: 956 ---------SSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLL 1006
S LG G P + ++ S +S ++ P A G G G
Sbjct: 323 MGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA--GASGRATGPEAAGGGGAGGGGGGY 380
Query: 1007 SPEASSP-YPPLPPRPSASPSSSLQPPPP-PPAPGELYRLP-PASAVAT--AQGPGAASS 1061
P SP Y A+ + +PPPP A + L PA+A AT A G G A
Sbjct: 381 RPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGG 440
Query: 1062 LSSDTGD-NGDYTEMAFG----------------VAATPPQPIAAPPKPEAARVASPTSG 1104
+ G G A+G + PPQP + PP P A S +
Sbjct: 441 QAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPD 500
Query: 1105 VKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTP-VSP 1163
L Q+ GV+ +P G HS T +P +S
Sbjct: 501 ----QLQGQLYGVQG-------------------EPYPGPAAHSQ----GLPTASPSLSY 533
Query: 1164 SFAHNPKRHNSASVENVSLRKSSEGGVGVGP----GGGDEPPTSPRQLQPAPPLAPQGRP 1219
S H+P S GG G GP GGG+ P+ + +PP GRP
Sbjct: 534 STGHSPAL-------------SGHGG-GWGPSSLGGGGEASPSHIIRPLQSPPAT--GRP 577
Query: 1220 ---WTPGQPGGLVGC----------PGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPP 1266
+PG PG + PG+G G +G +A PG PP
Sbjct: 578 PGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLA-----GPGGPP 632
Query: 1267 QP-------------QPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGA 1313
Q P PP RT GL+ G G GG G
Sbjct: 633 AERTEDEEFLIQHLLQAPSPP-----------RTSGADGLVGEDGAADASKGLGGSGGAG 681
Query: 1314 LPPANTY--ASIDFLSHHLK 1331
PP Y A D +HL+
Sbjct: 682 GPPGTPYELAKEDPQRYHLQ 701
Score = 52.8 bits (125), Expect = 2e-06
Identities = 209/933 (22%), Positives = 287/933 (30%), Gaps = 194/933 (20%)
Query: 373 AGAAAAGARPVSVAGSPLSPGPV-RAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSM 431
AGA GA + SP P P ++ H L GG + L P L S
Sbjct: 751 AGAKELGA---FLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLS 807
Query: 432 SMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGS 491
P + SP A+ L + PPPP P PP P PL R S G A+ S
Sbjct: 808 HAP-SPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR-SHGLEPAAPS 865
Query: 492 PSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSH 551
P SLD PG ++ P + +T G + G
Sbjct: 866 PRLRPEESLDP----PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAG---------- 911
Query: 552 CGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSA-- 609
+YR S + R LT+ + Q S + M F G A
Sbjct: 912 ---AYRSPSPQGTK------APRFVPLTSICFPDSLLQDEERSF--FPTMEEMFGGGAAD 960
Query: 610 --GRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGS 667
G+ P PED GD + G+ A D Y P PG A +G+G
Sbjct: 961 DYGKAGP--------------PEDEGDPKAGA--GPPPGPPAYDPYGPYCPGRA-SGAGP 1003
Query: 668 ---GSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASG 724
G + P P++V+A L AA P P PAP S P G
Sbjct: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASE-----PKGG 1058
Query: 725 GGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFF 784
+SP ++C +K KLL + + D PP
Sbjct: 1059 ----LTSP------------IFCSTKPK------KLLKTSSFHLLRRRD------PP--- 1087
Query: 785 SAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQAT 844
+ + + Y Y D D+ P L RL +
Sbjct: 1088 ------------------FQTPKKLYAQEYEFEADEDK---ADVPADIRLNPRRLPDLVS 1126
Query: 845 PGPSQAA-SAFGAGPTQPPHPVVPSPVR----PSGGRPEGFLGQRGRA-VRPTRLSLEGL 898
S+ A S G PP+P P R P+ + +G RGR +RP +
Sbjct: 1127 SCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAG 1186
Query: 899 PSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSL 958
P+ S +P+ G E G P PL + + +S
Sbjct: 1187 PASASTPTDGAK-KPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKA---GEGLGTSS 1242
Query: 959 GSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPY---- 1014
G GT +S S + + + +P SG LD L S + P
Sbjct: 1243 GDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAG 1302
Query: 1015 --PPL-PPR--PSASPSSSLQPPPPP------PAPGELYRLPPASAVATAQGPGAASSLS 1063
PPL PP+ P + P+ LQP PP P P + L A A ++G G
Sbjct: 1303 LTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSP 1362
Query: 1064 SDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQA 1123
D E+ + P + S K L E +S + L
Sbjct: 1363 CKRLDE----ELKRNLETLP-----------SFSSDEEDSVAKNRDLQESISSAISALD- 1406
Query: 1124 SQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLR 1183
DP + P G + P P P +++ + E L
Sbjct: 1407 ----DPPLAGPKDTSTPDGPPL--------APAAAVPGPPPLPGLPSANSNGTPEPPLLE 1454
Query: 1184 KSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRET 1243
+ P P +P+ P PP PQ P P P + P S P
Sbjct: 1455 EK--------PPPTPPPAPTPQPQPPPPPPPPQ--PALPSPPPLVAPTPSSPPPPPL--- 1501
Query: 1244 SAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLP 1276
P P P PPPPP P
Sbjct: 1502 ----------------PPPPPPAMPSPPPPPPP 1518
Score = 52.4 bits (124), Expect = 3e-06
Identities = 70/248 (28%), Positives = 90/248 (36%), Gaps = 32/248 (12%)
Query: 834 LEEERLEPQATPGPSQAAS--AFGAGPTQPPHPVVPSPVRPSG--------------GRP 877
L + L P +P S S A G P P P VP P PSG G
Sbjct: 1298 LYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGLG 1356
Query: 878 EGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPE---PKSPGEYINI----DFGEPGAR 930
G R + +LE LPS S E + +S I+ P
Sbjct: 1357 LGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDT 1416
Query: 931 LSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPK 990
+P PPL +AA P+++ +GTP + P P+ P
Sbjct: 1417 STPDGPPLAPAAAVPGPPPLPGLPSAN-SNGTP--EPPLLEEKPPPTPPPAPTPQPQPPP 1473
Query: 991 PGAPSGHPVGSLDGLLSPEASSPYPPL--PPRPSASPSSSLQPPPPPPAPGELYRLPPAS 1048
P P + S L++P SSP PP PP P A PS PPPPPPA L P
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP---PPPPPPAAAPLAAPPEEP 1530
Query: 1049 AVATAQGP 1056
A + + P
Sbjct: 1531 AAPSPEDP 1538
Score = 48.9 bits (115), Expect = 3e-05
Identities = 68/241 (28%), Positives = 80/241 (33%), Gaps = 67/241 (27%)
Query: 899 PSLPSMHEYPLPPE-PKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASS 957
PS+P+ P PP P P + FG GA L +A S L SP
Sbjct: 1315 PSVPARGLQPQPPATPAVPHPPPSGAFGLGGA---------LEAAESEGLGLGCPSPCKR 1365
Query: 958 LGSGT-------PGTSSDSR---------QRSPLSDYMNLDFSSPKSPKP-GAPSGHPVG 1000
L P SSD Q S S LD PK P G P+
Sbjct: 1366 LDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLA 1425
Query: 1001 S---------LDGLLSPEAS-SPYPPL-----PPRPSASPSSSLQPPPPPPAPGELYRLP 1045
L GL S ++ +P PPL PP P +P+ QPPPPPP P P
Sbjct: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
Query: 1046 PASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIA-----APPKPEAARVAS 1100
P T P PP P A PP P AA +A+
Sbjct: 1486 PPLVAPTPSSPPPP--------------------PLPPPPPPAMPSPPPPPPPAAAPLAA 1525
Query: 1101 P 1101
P
Sbjct: 1526 P 1526
Score = 44.3 bits (103), Expect = 8e-04
Identities = 76/295 (25%), Positives = 95/295 (32%), Gaps = 82/295 (27%)
Query: 677 PMSPASV---SAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPA 733
P+SP S P + LQP+ A A VP P+G A + G G SP
Sbjct: 1306 PLSPPKSVPPSVPARGLQPQPPATPA--VPHPPPSGAFGLGGALEAAESEGLGLGCPSPC 1363
Query: 734 ESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVT------------TGTP- 780
+ E+ S S E + + N D L S S A++ T TP
Sbjct: 1364 KRLDEELKRNLETLPSFSSDE--EDSVAKNRD-LQESISSAISALDDPPLAGPKDTSTPD 1420
Query: 781 -PDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERL 839
P AA PG PL G+P + P +LEE
Sbjct: 1421 GPPLAPAAAVPGPPPLPGLPSANSNGTPEP----------------------PLLEE--- 1455
Query: 840 EPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLP 899
+P TP P+ P PP P +PSP V PT P
Sbjct: 1456 KPPPTPPPAPTPQPQPPPPPPPPQPALPSP---------------PPLVAPT-------P 1493
Query: 900 SLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSP 954
S P P PP P P PP PP A A+ +A SP
Sbjct: 1494 SSPPPPPLPPPPPPAMPSP-------------PPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 42.4 bits (98), Expect = 0.003
Identities = 147/678 (21%), Positives = 217/678 (32%), Gaps = 93/678 (13%)
Query: 718 RTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTT 777
R +P++G G + A S E S + GS + H + +L Y P + T
Sbjct: 3 RNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRT-SHPETDILHRQAYAAPHPLQSYAT 61
Query: 778 GTPP----DFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRI 833
P F LH G P +L + ++ G S SS + +
Sbjct: 62 NHHPAGLSGLFDTGLHHAGS---AGPDASVMNLISALESRGPQPGPS-----ASSLLSQF 113
Query: 834 LEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRL 893
TPGP++ F +G P PS S + G R V P+ L
Sbjct: 114 RSPSWQTAMHTPGPTEL---FISGAL-PGSSTFPSSSALSAYQHPASFGSRPFPV-PSSL 168
Query: 894 SLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASS 953
SL+ P P + SP + +++ +P + P+ A L A
Sbjct: 169 SLQDPPFSPPANGL------LSPHDVLHL---KPSQAPTVPSSLGFERLAGGGVLGPAGL 219
Query: 954 PASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPV----GSLDGLLSPE 1009
+ PG L NL SS + S + G+ G PE
Sbjct: 220 GPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPE 279
Query: 1010 ASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDN 1069
+ P + P+S+ PPPPPPA + L S + G ++L+
Sbjct: 280 RALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYL---SCGGSYPSMGHRANLACSPLGG 336
Query: 1070 GDYTEMAFGVAATPPQPIAAPPK-----PEAARVASPTSG-------VKRLSLMEQVSGV 1117
G+ + A + P A PEAA G ++ G
Sbjct: 337 GEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396
Query: 1118 EAFLQASQPPDPHRGAKVIRADPQGG------RRRHSSETFSSTTTVTPVSPSFAHNPKR 1171
A + P P R + GG + S + +P P P+
Sbjct: 397 GAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQA 456
Query: 1172 H----NSASVENVSLRKSSEGGVGVGPGGGDEP------PTSPRQLQPAPPLAPQGRPWT 1221
+ +++S S GG P G P SP QLQ QG P+
Sbjct: 457 YGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQ-GQLYGVQGEPY- 514
Query: 1222 PGQPGGLVGCP--------GSGGSPMRRETSAGFQNGLNYIAIDVREEPG--LPPQPQPP 1271
PG G P +G SP G+ G + + P + P PP
Sbjct: 515 PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGW--GPSSLGGGGEASPSHIIRPLQSPP 572
Query: 1272 ----PPPLPQPGDKSSW-GRTRSLGGLISAVGVGSTGGGCGG-----------PGPGALP 1315
PP + PG + + ++ G GS G GG GPG P
Sbjct: 573 ATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGG-P 631
Query: 1316 PANTYASIDFLSHHLKEA 1333
PA +FL HL +A
Sbjct: 632 PAERTEDEEFLIQHLLQA 649
Score = 33.9 bits (76), Expect = 1.1
Identities = 30/107 (28%), Positives = 37/107 (34%), Gaps = 13/107 (12%)
Query: 434 PVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPS 493
P SPP +P S PPP P PP P P P P +A + P
Sbjct: 1480 PALPSPPPLVAPTPSS-----------PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528
Query: 494 DPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAET-PPARDGGGGGEF 539
+P S E P + + T ET A + GG G F
Sbjct: 1529 EPAAPS-PEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIF 1574
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 79.3 bits (194), Expect = 2e-14
Identities = 195/848 (22%), Positives = 271/848 (31%), Gaps = 170/848 (20%)
Query: 460 PPPPGPHPPLPHP-LHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRS 518
P PG P+P P L P++ S A P P L SP + S
Sbjct: 1811 PSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPES 1870
Query: 519 NTPESIAETPPARDGGGGGEFYGYMTMDR-PLSHCGRSYRRVSGDAAQD----------- 566
+TP + D G ++ P S G+ YR+ G+ ++
Sbjct: 1871 HTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSH 1930
Query: 567 ------LDRGLRKRTYSLTTPARQRPVPQPSSASL---DEYTLMRATFSGSAGRLCPSCP 617
+ T P ++ P P P S D Y M T G P+CP
Sbjct: 1931 SSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLG------PACP 1984
Query: 618 ASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMP 677
P LGA + P A + S + P
Sbjct: 1985 TREPP------------------------LGAAGDWPPCLSTKEAAAGRNTSAEKELSSP 2020
Query: 678 MSPASVSAPKQILQPRAAAAAAAAVPSAGPAGP--------------APTSAAGRTFPAS 723
+SP S+ + AA A VP GP AP + G + P +
Sbjct: 2021 ISPKSLQSDTPTFS--YAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLN 2078
Query: 724 GGGYKASSPAES-SPEDSGYMRMWCGSKLSMEHADG-KLLPNGDYLNVSPSDAVTTGTPP 781
G S S SP++SG W S E G + P + + SP + G+P
Sbjct: 2079 GNILSCSPDRRSPSPKESGRSH-WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPT 2137
Query: 782 DFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEP 841
+ H +S P+ + L P
Sbjct: 2138 LWPETEAH------------------------------------VSPPL-----DSHLGP 2156
Query: 842 QATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEG---FLGQRGRAVR---PTR--- 892
A P ASAFG QP P +PSP P P G F G R A+ PTR
Sbjct: 2157 -ARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSA-PCGSLAFSGDRALALAPGPPTRTRH 2214
Query: 893 ---LSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGA------RLSPPAPPLLASAA 943
L + PSL S P P P SPG + + P + S P+++S A
Sbjct: 2215 DEYLEVTKAPSLDS--SLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVA 2272
Query: 944 S--SSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGS 1001
S SL +A + L G + +PLS +P P P G
Sbjct: 2273 ERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGI 2332
Query: 1002 LDGLL-----SPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQG- 1055
L L + E SP+ +A+ + P PP PAP + A+ A +G
Sbjct: 2333 LPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGA 2392
Query: 1056 --PGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQ 1113
GA S DT + + G + PP +A P+ EA T +
Sbjct: 2393 WPEGAERSSRPDTLLSPEQPVCPAGGSGGPPS--SASPEVEAGPQGCATEPRPHRGELS- 2449
Query: 1114 VSGVEAFLQASQPP---DPHRGAKVIRADPQGGRRRHSSE-TFSSTTTVTPVSPSFAHN- 1168
+FL PP D + +R +GGRRR T VT +P + +
Sbjct: 2450 ----PSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASD 2505
Query: 1169 -----------PKRHNSASVENVSLRKSSEGG--VGVGPGGGDEPPTSPRQLQPAPPL-A 1214
P+ S+ + S E G + V GG PR PPL
Sbjct: 2506 SGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQ 2565
Query: 1215 PQGRPWTP 1222
P RP P
Sbjct: 2566 PDPRPSPP 2573
Score = 53.9 bits (128), Expect = 1e-06
Identities = 182/830 (21%), Positives = 266/830 (32%), Gaps = 188/830 (22%)
Query: 464 GPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPES 523
GP+ PL G+R G A A S + E S A PE
Sbjct: 1900 GPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSS--KVPEASKS----HATTEPEQTEPEQ 1953
Query: 524 IAETP-PARDGGGGGEFYGYM----------TMDRPLSHCGRSYRRVS-GDAAQDLDRGL 571
TP P + Y M T + PL G +S +AA +
Sbjct: 1954 REPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSA 2013
Query: 572 RKRTYSLTTP-ARQRPVPQPSSASLDEYTLMRATFSGSA---GRLCPSCPASSPKVAYHP 627
K S +P + Q P S A+L T+ G + P+ P +P ++ P
Sbjct: 2014 EKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGP 2073
Query: 628 YPEDYGDIEIGS--HRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSA 685
P G+I S RS S + T + L + P P +
Sbjct: 2074 SPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPM 2133
Query: 686 PKQILQPRAAAAAAAAVPS-AGPAGPAPTSAAGRTFPASGGGYKA--------SSPAESS 736
L P A + + S GPA P+ FPAS G+ + SPAE
Sbjct: 2134 GSPTLWPETEAHVSPPLDSHLGPARPS------LDFPASAFGFSSLQPAPPQLPSPAEPR 2187
Query: 737 PEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLR 796
G + L++ + +YL V+ + ++ + P + PG L
Sbjct: 2188 SAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ--LPSPSSPGAPLL- 2244
Query: 797 GVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGR-----ILEEERLEPQATPGPSQAA 851
S+LPR + G S+ + S V + E+ + PG AA
Sbjct: 2245 -------SNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAA 2297
Query: 852 -SAFGAGPTQPPHP------VVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSM 904
S + P P P + P+P P G G + P L +
Sbjct: 2298 HSLWDLTPLSPAPPASLDLALAPAPSLP---------GDMGDGILPCHLECSEAAT---- 2344
Query: 905 HEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPG 964
E SP + + D G + P PP A A + + +A+ PA G+ G
Sbjct: 2345 -------EKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENE-EAAACPAWERGAWPEG 2396
Query: 965 TSSDSRQRSPLSDYMNLDFSSPKSPK-PGAPSGHPVGSLDGLLSPEASS-----PYPPLP 1018
SR + L SP+ P P SG P S SPE + P P
Sbjct: 2397 AERSSRPDTLL---------SPEQPVCPAGGSGGPPSS----ASPEVEAGPQGCATEPRP 2443
Query: 1019 PRPSASPSSSLQPPPPPP-----------------------APGE-------LYRLPPAS 1048
R SP S L PP PP PG PP S
Sbjct: 2444 HRGELSP-SFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTS 2502
Query: 1049 A-------------VATAQGPGAASSLSSDTGDNGDY--TEMAFGVAAT----------- 1082
A T + P + + D+ ++GD+ + A GV+ T
Sbjct: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPP 2562
Query: 1083 --PPQPIAAPPKPEAAR-----VASPTSGVKRLSLMEQVSG----------------VEA 1119
P P +PP+P+ ++S + V+RL E+V G
Sbjct: 2563 LPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRL 2622
Query: 1120 FLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNP 1169
L+ + P P +G P R S+T+ VTP H+P
Sbjct: 2623 DLRGKRSPTPGKG-------PADRASRAPPRPRSTTSQVTPAEEKDGHSP 2665
Score = 47.0 bits (110), Expect = 1e-04
Identities = 80/385 (20%), Positives = 131/385 (34%), Gaps = 75/385 (19%)
Query: 961 GTPGTSSDSRQRSPLSDYMNLDFSSPKSPK----------PGAPSGHPVGSLDGLLSPEA 1010
G P D RSP S P SP PG S P L + E
Sbjct: 1779 GLPPEEEDKLTRSPFEI-----ISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEP 1833
Query: 1011 SSP-----YPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSD 1065
++P PP P+ P + L P P PP P P + TA+ +++
Sbjct: 1834 TTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEG 1893
Query: 1066 TGD--NGDYTEMAF------------GVAATPPQPIAAPPKPEAARVASPTS-------- 1103
+ G Y+ + G A P + + PEA++ + T
Sbjct: 1894 AAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQ 1953
Query: 1104 ----------GVKRLSLMEQV--SGVEAFLQASQPPDPHRG---AKVIRADPQGGRRRHS 1148
+ + EQ+ +G+ +PP G + + GR +
Sbjct: 1954 REPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSA 2013
Query: 1149 SETFSSTTTVTPVSP-SFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQL 1207
+ SS P+SP S + + A++ ++ E PG EP +P +
Sbjct: 2014 EKELSS-----PISPKSLQSDTPTFSYAALAGPTVPPRPE------PGPSMEPSLTPPAV 2062
Query: 1208 QPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGL---NYIAIDVREEPGL 1264
P P+ +G +P G ++ C SP +E+ + + + RE+P
Sbjct: 2063 PPRAPILSKGP--SPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEK 2120
Query: 1265 PPQPQPPPPPLPQPGDKSSWGRTRS 1289
Q PP P+P G + W T +
Sbjct: 2121 EAQSPSPPHPIPM-GSPTLWPETEA 2144
Score = 46.6 bits (109), Expect = 2e-04
Identities = 100/392 (25%), Positives = 135/392 (34%), Gaps = 86/392 (21%)
Query: 868 SPVRPSGGRPEGFLGQRGRAVRPTRLSLEG-LPSLPSMHEYPLP----PEPKSPG----- 917
SP+ + EG + GRA P + S +P H P PE + P
Sbjct: 1903 SPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDE 1962
Query: 918 ---EYINIDFGEPGARLSPPAP---PLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQ 971
+Y +I L P P P L +A LS A+ TS++
Sbjct: 1963 RSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRN-----TSAEKEL 2017
Query: 972 RSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSS--SL 1029
SP+S PKS + P+ +L G P +PPRP PS SL
Sbjct: 2018 SSPIS---------PKSLQSDTPT-FSYAALAG----------PTVPPRPEPGPSMEPSL 2057
Query: 1030 QPPPPPPAPGELYR--LPPASAVATAQGPGAASSLSSDTG-----DNGDYTEMAFGVAAT 1082
PP PP L + PP + + P S ++G D+ +E+ G
Sbjct: 2058 TPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQ 2117
Query: 1083 PPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQG 1142
P + +P P + SPT E S P D H G D
Sbjct: 2118 PEKEAQSPSPPHPIPMGSPT------------LWPETEAHVSPPLDSHLGPARPSLDFPA 2165
Query: 1143 GRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPT 1202
S+ FSS P PS P SA SL S + + + PG PPT
Sbjct: 2166 -----SAFGFSSLQPAPPQLPS----PAEPRSAPCG--SLAFSGDRALALAPG----PPT 2210
Query: 1203 SPR-----QLQPAPPL---APQ-GRPWTPGQP 1225
R ++ AP L PQ P +PG P
Sbjct: 2211 RTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAP 2242
Score = 30.8 bits (68), Expect = 9.1
Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 19/128 (14%)
Query: 1186 SEGGVGVGPGGGDEPPTSPRQLQPAPPLAP-----QGRPWTPGQPGGLVGCPGSGGSP-M 1239
+E VG+ P D+ SP ++ +PP +P Q P PGQ + P P M
Sbjct: 1774 AESPVGLPPEEEDKLTRSPFEII-SPPASPPEMVGQRVPSAPGQESPI---PDPKLMPHM 1829
Query: 1240 RRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKS------SWGRTRSLGGL 1293
+ E + + L I V ++ LPP P P P P P +S SWG T +
Sbjct: 1830 KNEPTT--PSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWG-TAEYDSV 1886
Query: 1294 ISAVGVGS 1301
++AV G+
Sbjct: 1887 VAAVQEGA 1894
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 79.0 bits (193), Expect = 3e-14
Identities = 179/781 (22%), Positives = 255/781 (32%), Gaps = 215/781 (27%)
Query: 618 ASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTP-------GAALAGSGSGSC 670
AS+PKV E+ + E + + P +P G +L GS
Sbjct: 62 ASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDP 121
Query: 671 RSDDYMPMSPA-SVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKA 729
R D S + S+ +P + +++ + P A P P P FP S
Sbjct: 122 RDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP-ARPYHPPPL------FPPS------ 168
Query: 730 SSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDA----VTTGTPPDFFS 785
P +S+P + S E + P G + + P + G PP
Sbjct: 169 PQPPDSTPRQP---------EASFE-PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH-- 216
Query: 786 AALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATP 845
L+PGG G S P K GG + +S VG ++ P TP
Sbjct: 217 PQLYPGGT------GGVLSGPPMGPK-----GGGA------ASSVGGPNGGKQHPPPTTP 259
Query: 846 GPSQAASAFGAGPTQPPH--------PVVPSP-----VRPSGGRPEGFLGQRGRAVRPTR 892
++ A GA PT+PP P P P V P+ P + P
Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG 319
Query: 893 LSLEGLPS-LPSMHEYP-----LPPEPKSPGEYINIDFGEPGARLSPPAPPLL--ASAAS 944
L + LP LPS H LPP P+ P A S PAPP+ S++S
Sbjct: 320 LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSS 379
Query: 945 SSSLLSASSPASSLGSGTPGTSSDSRQRSPLS----DYMNLDFSSPKSPKPGAPS----- 995
SSS ++SS +SS S +P +S + P S +++ PK +P PS
Sbjct: 380 SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS 439
Query: 996 -GHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPP---------------------- 1032
G P G L +++ P P PS S+ PP
Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFP--PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497
Query: 1033 -----------PPPPA------------------------------PGELYRLPPASAVA 1051
PPPP PG + PP S V+
Sbjct: 498 QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVS 557
Query: 1052 TAQG-----PGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAP---PKPEAARVASPTS 1103
+Q P ++SS SS + G Y + P P P P P TS
Sbjct: 558 YSQAGPNGPPVSSSSNSSSSTSQGSY-------PCSHPSPSQGPQGAPYPFPPVPTVTTS 610
Query: 1104 GVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSP 1163
+++ V+ A + + PP P P G+R S + + T
Sbjct: 611 SATLSTVIATVASSPAGYKTASPPGP----------PPYGKRAPSPGAYKTAT------- 653
Query: 1164 SFAHNPKRHNSASVENVSLRKSSEGGVGVGPG-GGDEPPTSPRQLQPAPPLAPQGRPWTP 1222
P + S + G PG G PP P +P P G P P
Sbjct: 654 -----PPGYKPGSPPSFR--------TGTPPGYRGTSPPAGPGTFKPGSPTVGPG-PLPP 699
Query: 1223 GQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPG---------LPPQPQPPPP 1273
P GL P +P +G A +++EP +PP P PP
Sbjct: 700 AGPSGLPSLPPPPAAP---------ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750
Query: 1274 P 1274
P
Sbjct: 751 P 751
Score = 68.9 bits (167), Expect = 3e-11
Identities = 165/708 (23%), Positives = 246/708 (34%), Gaps = 111/708 (15%)
Query: 440 PAATSPGSLSSSSGHGSGSYPPPPGPH--PPLPHPLHHGPGQRPSSGSASASGSPS--DP 495
P+ SPGS+ + S SG P P+ PPL P P P AS PS
Sbjct: 133 PSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPT 192
Query: 496 GFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRS 555
G+ + E P R F + P P GG GG G P+ G
Sbjct: 193 GYHAPME----PPTSRMFQAPPGAPPPH----PQLYPGGTGGVLSG-----PPMGPKG-- 237
Query: 556 YRRVSGDAAQDLDRGLRKRTYSLTTP-------ARQRPVPQPSSASLDEYTLMRATFSGS 608
G A+ K+ TTP A P +P + + L A +
Sbjct: 238 ----GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 609 AGRLCPSCPASSPKVAYHPY------PEDYGDIEIGSHRSSSSNLGADDGYMPMTP--GA 660
+ P+ P P A P P G + H S +G G +P P G
Sbjct: 294 FPHVTPNLP---PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGP 350
Query: 661 ALAGSGSGSCRSDDYMPMSPASVSAPKQILQ-PRAAAAAAAAVPSAGPAGPAPTSAAGRT 719
LA S + PAS SAP ++ P +++++++A S+ + +S++
Sbjct: 351 TLAPSPHS---------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS---SSSSASP 398
Query: 720 FPASGG--GYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVS-PSDAVT 776
FPAS Y S P +S LS+ + K Y S PS AV
Sbjct: 399 FPASQALPSYPHSFPPPTS--------------LSVSNQPPK------YTQPSLPSQAVW 438
Query: 777 TGTPPD-------FFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSP 829
+ PP ++ HPG P P S + + Q
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFP----PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494
Query: 830 VGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSP----VRPSGGRPEGFLGQRG 885
+ +++ P P G + HP SP +RP P L
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP-AHLPPPH 553
Query: 886 RAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLS-PPAPPLLASAAS 944
V ++ G P S + + P + + G GA PP P + S+A+
Sbjct: 554 SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT 613
Query: 945 SSSLLS--ASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSL 1002
S++++ ASSPA + PG ++ Y ++P KPG+P G+
Sbjct: 614 LSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKT---ATPPGYKPGSPPSFRTGTP 670
Query: 1003 DGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPA-PGELYRLPPASAVATAQGPGAASS 1061
G PP P S ++ P P PPA P L LPP A + P +A+
Sbjct: 671 PGYRGTS-----PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQ 725
Query: 1062 LSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLS 1109
+ + + + E + PP +PP P+ V S S R +
Sbjct: 726 IKQEPAEEYETPE-----SPVPPARSPSPP-PKVVDVPSHASQSARFN 767
Score = 54.7 bits (130), Expect = 6e-07
Identities = 143/636 (22%), Positives = 194/636 (30%), Gaps = 141/636 (22%)
Query: 382 PVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPA 441
P+ S + P AP GG GG S + P GG S PP
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 442 ATSPGSLSSSSGHGS------------GSYP--PPPG---------PHPPLPHPLHHGPG 478
T+P S+SSS G+ G+ P PPP P PP PL++
Sbjct: 257 -TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASA 315
Query: 479 QRPSSGSASASGSPSDPGFMSLDEYGSSPGDLR----AFCSHRSNTPESIAETPPARDGG 534
P G+ G P M G PG + A H S A PP R
Sbjct: 316 SPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR--- 372
Query: 535 GGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQ-DLDRGLRKRTYSLTTP-----ARQRP-V 587
+ Y + + S S A+ + L +S P + Q P
Sbjct: 373 -----FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKY 427
Query: 588 PQPSSASL----------DEYTLMRATFSGSAGRLCPSCPASS----PKVAYHPYPEDYG 633
QPS S Y + A + G PS A S P +H + +
Sbjct: 428 TQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQ 487
Query: 634 DIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVS------APK 687
+ + P PGA GS MSP+ S P
Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA 547
Query: 688 QILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAES-SPEDSGYMRMW 746
+ P + + + AGP GP +S++ + S G Y S P+ S P+ + Y
Sbjct: 548 HLPPPHSQVSYS----QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY---- 599
Query: 747 CGSKLSMEHADGKLLPNGDYLNVSPSDA------VTTGTPPDFFSAALHPGGEPL---RG 797
P V+ S A T + P + A PG P
Sbjct: 600 ---------------PFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 798 VPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAAS-AFGA 856
PG ++ P YK G + + P R P A PG + S G
Sbjct: 645 SPGAYKTATPPGYKP-----GSPPSFRTGTPPGYR-----GTSPPAGPGTFKPGSPTVGP 694
Query: 857 GPTQPPHP-----VVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPP 911
GP P P + P P P+ G P LS + P+ EY P
Sbjct: 695 GPLPPAGPSGLPSLPPPPAAPASGPP---------------LSATQIKQEPA-EEYETPE 738
Query: 912 EPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSS 947
P P SP PP + S +S
Sbjct: 739 SPVPPAR-------------SPSPPPKVVDVPSHAS 761
Score = 46.2 bits (108), Expect = 2e-04
Identities = 105/482 (21%), Positives = 161/482 (33%), Gaps = 92/482 (19%)
Query: 316 PISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTAS-----EGDGG 370
P + P A H NLPP ++ +A+PP S +G GG
Sbjct: 286 PSAPPPANFPHVTPNLPPPPA----LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341
Query: 371 AAAG-----AAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSK----VALLPA 421
G A + A S P+R P S S + S S + PA
Sbjct: 342 LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 422 GGALQ---HS--RSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHG 476
AL HS S+ V++ PP T P SL S + G PPPP P+ L +
Sbjct: 402 SQALPSYPHSFPPPTSLSVSNQPPKYTQP-SLPSQAVWSQG--PPPPPPYGRLLANSNAH 458
Query: 477 PGQRPSSGSASASGSPSDPGF------MSLDEYGSSPGDLRAFCSHRSNTPESIAETPPA 530
PG P S A ++ P + + H ++ P P
Sbjct: 459 PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Query: 531 RDGGGGGEFYGYMTMDR--------------PLSHCGRSYRRVSGD-----AAQDLDRGL 571
+GG + Y P H SY + + ++ +
Sbjct: 519 LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST 578
Query: 572 RKRTYSLTTPARQR----------PVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSP 621
+ +Y + P+ + PVP +++S T++ S AG S P P
Sbjct: 579 SQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638
Query: 622 KVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPA 681
P P G++++++ GY P +P + G+ G Y SP
Sbjct: 639 YGKRAPSP--------GAYKTAT-----PPGYKPGSPPSFRTGTPPG------YRGTSP- 678
Query: 682 SVSAPKQILQPRAAAAAAAAVPSAGPAG----PAPTSAAGRTFPASGGGYKASSPAESSP 737
A +P + +P AGP+G P P +A PASG A+ +
Sbjct: 679 --PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA-----PASGPPLSATQIKQEPA 731
Query: 738 ED 739
E+
Sbjct: 732 EE 733
Score = 34.7 bits (78), Expect = 0.63
Identities = 168/779 (21%), Positives = 233/779 (29%), Gaps = 190/779 (24%)
Query: 302 PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV 361
P + S S GS +P PG +LPP S+ A P SS
Sbjct: 529 PYAMSPSLGSLRPYP---PGP------AHLPPPH------SQVSYSQAGPNGPPVSSSSN 573
Query: 362 RTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPA 421
++S G + P G+P PV + S TLS + VA PA
Sbjct: 574 SSSSTSQGSYPCSHPSPSQGP---QGAPYPFPPVPTVTTSSATLSTVI----ATVASSPA 626
Query: 422 G-------GALQHSRSMSMPVAH---SPPAAT--SPGSLSSSSGHGSGSYPPPPGPHPPL 469
G G + + P A+ +PP SP S + + G PP GP
Sbjct: 627 GYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFK 686
Query: 470 PHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGS--SPGDLRAFCSHRSNTPESIAET 527
P GPG P +G SG PS P + G S ++ + TPES
Sbjct: 687 PGSPTVGPGPLPPAG---PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES--PV 741
Query: 528 PPARDGGGGGEFYGYMT-----------MDRPLSHCGRS-----------YRRVSGDAAQ 565
PPAR + + +DR + C RS + D +
Sbjct: 742 PPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVE 801
Query: 566 DLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAY 625
+ R +R R+R + E L R+ GR CP+ P V +
Sbjct: 802 KVRREAEQRAREEKEREREREREKERERE-KERELERSVKLAQEGRAPVECPSLGP-VPH 859
Query: 626 HPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSA 685
P P PG+A+A Y+ ++
Sbjct: 860 RP---------------------------PFEPGSAVA-------TVPPYLGPDTPALRT 885
Query: 686 PKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRM 745
+ +P + P P G G PA +S PA E R
Sbjct: 886 LSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPA----LYSSDPAAREREREARER- 940
Query: 746 WCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSS 805
+L P V PS+ EPL GVPG
Sbjct: 941 ---------DLRDRLKPG---FEVKPSEL------------------EPLHGVPGPGLDP 970
Query: 806 LPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPV 865
PR GG L P G L P P + A AGP
Sbjct: 971 FPRH-------GG----LALQPGPPG--LHPFPFHPSLGP-LERERLALAAGPA------ 1010
Query: 866 VPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFG 925
+RP E +R A R L + L L ++ P + ++++
Sbjct: 1011 ----LRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQ 1066
Query: 926 EPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSS 985
+ S PL+ AS S L PA +L
Sbjct: 1067 DAIHAASASVHPLIDPLASGSHLTRIPYPAGTL--------------------------- 1099
Query: 986 PKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRL 1044
P P P HP+ + L ++PY LP SA S++ Q EL RL
Sbjct: 1100 ---PNPLLP--HPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAELQRL 1153
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 79.0 bits (193), Expect = 3e-14
Identities = 179/781 (22%), Positives = 255/781 (32%), Gaps = 215/781 (27%)
Query: 618 ASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTP-------GAALAGSGSGSC 670
AS+PKV E+ + E + + P +P G +L GS
Sbjct: 62 ASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDP 121
Query: 671 RSDDYMPMSPA-SVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKA 729
R D S + S+ +P + +++ + P A P P P FP S
Sbjct: 122 RDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP-ARPYHPPPL------FPPS------ 168
Query: 730 SSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDA----VTTGTPPDFFS 785
P +S+P + S E + P G + + P + G PP
Sbjct: 169 PQPPDSTPRQP---------EASFE-PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH-- 216
Query: 786 AALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATP 845
L+PGG G S P K GG + +S VG ++ P TP
Sbjct: 217 PQLYPGGT------GGVLSGPPMGPK-----GGGA------ASSVGGPNGGKQHPPPTTP 259
Query: 846 GPSQAASAFGAGPTQPPH--------PVVPSP-----VRPSGGRPEGFLGQRGRAVRPTR 892
++ A GA PT+PP P P P V P+ P + P
Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG 319
Query: 893 LSLEGLPS-LPSMHEYP-----LPPEPKSPGEYINIDFGEPGARLSPPAPPLL--ASAAS 944
L + LP LPS H LPP P+ P A S PAPP+ S++S
Sbjct: 320 LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSS 379
Query: 945 SSSLLSASSPASSLGSGTPGTSSDSRQRSPLS----DYMNLDFSSPKSPKPGAPS----- 995
SSS ++SS +SS S +P +S + P S +++ PK +P PS
Sbjct: 380 SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS 439
Query: 996 -GHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPP---------------------- 1032
G P G L +++ P P PS S+ PP
Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFP--PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497
Query: 1033 -----------PPPPA------------------------------PGELYRLPPASAVA 1051
PPPP PG + PP S V+
Sbjct: 498 QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVS 557
Query: 1052 TAQG-----PGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAP---PKPEAARVASPTS 1103
+Q P ++SS SS + G Y + P P P P P TS
Sbjct: 558 YSQAGPNGPPVSSSSNSSSSTSQGSY-------PCSHPSPSQGPQGAPYPFPPVPTVTTS 610
Query: 1104 GVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSP 1163
+++ V+ A + + PP P P G+R S + + T
Sbjct: 611 SATLSTVIATVASSPAGYKTASPPGP----------PPYGKRAPSPGAYKTAT------- 653
Query: 1164 SFAHNPKRHNSASVENVSLRKSSEGGVGVGPG-GGDEPPTSPRQLQPAPPLAPQGRPWTP 1222
P + S + G PG G PP P +P P G P P
Sbjct: 654 -----PPGYKPGSPPSFR--------TGTPPGYRGTSPPAGPGTFKPGSPTVGPG-PLPP 699
Query: 1223 GQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPG---------LPPQPQPPPP 1273
P GL P +P +G A +++EP +PP P PP
Sbjct: 700 AGPSGLPSLPPPPAAP---------ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750
Query: 1274 P 1274
P
Sbjct: 751 P 751
Score = 68.9 bits (167), Expect = 3e-11
Identities = 165/708 (23%), Positives = 246/708 (34%), Gaps = 111/708 (15%)
Query: 440 PAATSPGSLSSSSGHGSGSYPPPPGPH--PPLPHPLHHGPGQRPSSGSASASGSPS--DP 495
P+ SPGS+ + S SG P P+ PPL P P P AS PS
Sbjct: 133 PSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPT 192
Query: 496 GFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRS 555
G+ + E P R F + P P GG GG G P+ G
Sbjct: 193 GYHAPME----PPTSRMFQAPPGAPPPH----PQLYPGGTGGVLSG-----PPMGPKG-- 237
Query: 556 YRRVSGDAAQDLDRGLRKRTYSLTTP-------ARQRPVPQPSSASLDEYTLMRATFSGS 608
G A+ K+ TTP A P +P + + L A +
Sbjct: 238 ----GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 609 AGRLCPSCPASSPKVAYHPY------PEDYGDIEIGSHRSSSSNLGADDGYMPMTP--GA 660
+ P+ P P A P P G + H S +G G +P P G
Sbjct: 294 FPHVTPNLP---PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGP 350
Query: 661 ALAGSGSGSCRSDDYMPMSPASVSAPKQILQ-PRAAAAAAAAVPSAGPAGPAPTSAAGRT 719
LA S + PAS SAP ++ P +++++++A S+ + +S++
Sbjct: 351 TLAPSPHS---------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS---SSSSASP 398
Query: 720 FPASGG--GYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVS-PSDAVT 776
FPAS Y S P +S LS+ + K Y S PS AV
Sbjct: 399 FPASQALPSYPHSFPPPTS--------------LSVSNQPPK------YTQPSLPSQAVW 438
Query: 777 TGTPPD-------FFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSP 829
+ PP ++ HPG P P S + + Q
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFP----PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494
Query: 830 VGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSP----VRPSGGRPEGFLGQRG 885
+ +++ P P G + HP SP +RP P L
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP-AHLPPPH 553
Query: 886 RAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLS-PPAPPLLASAAS 944
V ++ G P S + + P + + G GA PP P + S+A+
Sbjct: 554 SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT 613
Query: 945 SSSLLS--ASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSL 1002
S++++ ASSPA + PG ++ Y ++P KPG+P G+
Sbjct: 614 LSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKT---ATPPGYKPGSPPSFRTGTP 670
Query: 1003 DGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPA-PGELYRLPPASAVATAQGPGAASS 1061
G PP P S ++ P P PPA P L LPP A + P +A+
Sbjct: 671 PGYRGTS-----PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQ 725
Query: 1062 LSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLS 1109
+ + + + E + PP +PP P+ V S S R +
Sbjct: 726 IKQEPAEEYETPE-----SPVPPARSPSPP-PKVVDVPSHASQSARFN 767
Score = 54.7 bits (130), Expect = 6e-07
Identities = 143/636 (22%), Positives = 194/636 (30%), Gaps = 141/636 (22%)
Query: 382 PVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPA 441
P+ S + P AP GG GG S + P GG S PP
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 442 ATSPGSLSSSSGHGS------------GSYP--PPPG---------PHPPLPHPLHHGPG 478
T+P S+SSS G+ G+ P PPP P PP PL++
Sbjct: 257 -TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASA 315
Query: 479 QRPSSGSASASGSPSDPGFMSLDEYGSSPGDLR----AFCSHRSNTPESIAETPPARDGG 534
P G+ G P M G PG + A H S A PP R
Sbjct: 316 SPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR--- 372
Query: 535 GGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQ-DLDRGLRKRTYSLTTP-----ARQRP-V 587
+ Y + + S S A+ + L +S P + Q P
Sbjct: 373 -----FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKY 427
Query: 588 PQPSSASL----------DEYTLMRATFSGSAGRLCPSCPASS----PKVAYHPYPEDYG 633
QPS S Y + A + G PS A S P +H + +
Sbjct: 428 TQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQ 487
Query: 634 DIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVS------APK 687
+ + P PGA GS MSP+ S P
Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA 547
Query: 688 QILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAES-SPEDSGYMRMW 746
+ P + + + AGP GP +S++ + S G Y S P+ S P+ + Y
Sbjct: 548 HLPPPHSQVSYS----QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY---- 599
Query: 747 CGSKLSMEHADGKLLPNGDYLNVSPSDA------VTTGTPPDFFSAALHPGGEPL---RG 797
P V+ S A T + P + A PG P
Sbjct: 600 ---------------PFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 798 VPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAAS-AFGA 856
PG ++ P YK G + + P R P A PG + S G
Sbjct: 645 SPGAYKTATPPGYKP-----GSPPSFRTGTPPGYR-----GTSPPAGPGTFKPGSPTVGP 694
Query: 857 GPTQPPHP-----VVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPP 911
GP P P + P P P+ G P LS + P+ EY P
Sbjct: 695 GPLPPAGPSGLPSLPPPPAAPASGPP---------------LSATQIKQEPA-EEYETPE 738
Query: 912 EPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSS 947
P P SP PP + S +S
Sbjct: 739 SPVPPAR-------------SPSPPPKVVDVPSHAS 761
Score = 46.2 bits (108), Expect = 2e-04
Identities = 105/482 (21%), Positives = 161/482 (33%), Gaps = 92/482 (19%)
Query: 316 PISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTAS-----EGDGG 370
P + P A H NLPP ++ +A+PP S +G GG
Sbjct: 286 PSAPPPANFPHVTPNLPPPPA----LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341
Query: 371 AAAG-----AAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSK----VALLPA 421
G A + A S P+R P S S + S S + PA
Sbjct: 342 LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 422 GGALQ---HS--RSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHG 476
AL HS S+ V++ PP T P SL S + G PPPP P+ L +
Sbjct: 402 SQALPSYPHSFPPPTSLSVSNQPPKYTQP-SLPSQAVWSQG--PPPPPPYGRLLANSNAH 458
Query: 477 PGQRPSSGSASASGSPSDPGF------MSLDEYGSSPGDLRAFCSHRSNTPESIAETPPA 530
PG P S A ++ P + + H ++ P P
Sbjct: 459 PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Query: 531 RDGGGGGEFYGYMTMDR--------------PLSHCGRSYRRVSGD-----AAQDLDRGL 571
+GG + Y P H SY + + ++ +
Sbjct: 519 LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST 578
Query: 572 RKRTYSLTTPARQR----------PVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSP 621
+ +Y + P+ + PVP +++S T++ S AG S P P
Sbjct: 579 SQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638
Query: 622 KVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPA 681
P P G++++++ GY P +P + G+ G Y SP
Sbjct: 639 YGKRAPSP--------GAYKTAT-----PPGYKPGSPPSFRTGTPPG------YRGTSP- 678
Query: 682 SVSAPKQILQPRAAAAAAAAVPSAGPAG----PAPTSAAGRTFPASGGGYKASSPAESSP 737
A +P + +P AGP+G P P +A PASG A+ +
Sbjct: 679 --PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA-----PASGPPLSATQIKQEPA 731
Query: 738 ED 739
E+
Sbjct: 732 EE 733
Score = 34.7 bits (78), Expect = 0.63
Identities = 168/779 (21%), Positives = 233/779 (29%), Gaps = 190/779 (24%)
Query: 302 PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV 361
P + S S GS +P PG +LPP S+ A P SS
Sbjct: 529 PYAMSPSLGSLRPYP---PGP------AHLPPPH------SQVSYSQAGPNGPPVSSSSN 573
Query: 362 RTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPA 421
++S G + P G+P PV + S TLS + VA PA
Sbjct: 574 SSSSTSQGSYPCSHPSPSQGP---QGAPYPFPPVPTVTTSSATLSTVI----ATVASSPA 626
Query: 422 G-------GALQHSRSMSMPVAH---SPPAAT--SPGSLSSSSGHGSGSYPPPPGPHPPL 469
G G + + P A+ +PP SP S + + G PP GP
Sbjct: 627 GYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFK 686
Query: 470 PHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGS--SPGDLRAFCSHRSNTPESIAET 527
P GPG P +G SG PS P + G S ++ + TPES
Sbjct: 687 PGSPTVGPGPLPPAG---PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES--PV 741
Query: 528 PPARDGGGGGEFYGYMT-----------MDRPLSHCGRS-----------YRRVSGDAAQ 565
PPAR + + +DR + C RS + D +
Sbjct: 742 PPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVE 801
Query: 566 DLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAY 625
+ R +R R+R + E L R+ GR CP+ P V +
Sbjct: 802 KVRREAEQRAREEKEREREREREKERERE-KERELERSVKLAQEGRAPVECPSLGP-VPH 859
Query: 626 HPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSA 685
P P PG+A+A Y+ ++
Sbjct: 860 RP---------------------------PFEPGSAVA-------TVPPYLGPDTPALRT 885
Query: 686 PKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRM 745
+ +P + P P G G PA +S PA E R
Sbjct: 886 LSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPA----LYSSDPAAREREREARER- 940
Query: 746 WCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSS 805
+L P V PS+ EPL GVPG
Sbjct: 941 ---------DLRDRLKPG---FEVKPSEL------------------EPLHGVPGPGLDP 970
Query: 806 LPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPV 865
PR GG L P G L P P + A AGP
Sbjct: 971 FPRH-------GG----LALQPGPPG--LHPFPFHPSLGP-LERERLALAAGPA------ 1010
Query: 866 VPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFG 925
+RP E +R A R L + L L ++ P + ++++
Sbjct: 1011 ----LRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQ 1066
Query: 926 EPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSS 985
+ S PL+ AS S L PA +L
Sbjct: 1067 DAIHAASASVHPLIDPLASGSHLTRIPYPAGTL--------------------------- 1099
Query: 986 PKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRL 1044
P P P HP+ + L ++PY LP SA S++ Q EL RL
Sbjct: 1100 ---PNPLLP--HPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAELQRL 1153
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 78.2 bits (191), Expect = 5e-14
Identities = 261/1163 (22%), Positives = 394/1163 (33%), Gaps = 238/1163 (20%)
Query: 271 WMQADDSVVAQNIHETILEAMKA-LKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLV 329
W A Q H+ + +A K +++ +K + SS P S+ A H
Sbjct: 237 WWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETR 296
Query: 330 NLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSP 389
S+TG + AA +++ S +T D A G+++ GA + G P
Sbjct: 297 ERSMSETG--------TAAAPGVSSELLSVAAQTLLSSDT-KAPGSSSCGAERLHTVGGP 347
Query: 390 LSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHS-PPAATSPGSL 448
S P S H+L GG + + + ++ +S P ++S P +T G+
Sbjct: 348 GSARPRAFSHSGVHSLDGG---------EVDSQALQELTQMVSGPASYSGPKPSTQYGAP 398
Query: 449 SSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASAS-------GSPSDPGFMSLD 501
+ G G G PPL P QR +S ++ D ++ D
Sbjct: 399 GPFAAPGEGGALAATG-RPPL-LPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADD 456
Query: 502 EYGSSPGDLRAFCSHR---SNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRR 558
+G++ DL+ C R S + +S E P G G F + +HC R
Sbjct: 457 GFGTTDIDLK--CKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSS--FTHC-RPPLD 511
Query: 559 VSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATF-------SGSAGR 611
D K S + + P +SA+ ++L TF +AG
Sbjct: 512 PEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAA-TSFSLGSGTFKAQESGQGSTAGP 570
Query: 612 LCPSCPA----SSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGS 667
L P P ++P A P D R ++G + P A +G G+
Sbjct: 571 LRPPPPGAGGPATPSKATRFLPMDPATF----RRKRPESVGGLEPPGPSVIAAPPSGGGN 626
Query: 668 ----------------GSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPA 711
G R +P +PA A P + AA P
Sbjct: 627 ILQTLVLPPNKEEQEGGGAR----VPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSST 682
Query: 712 PTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVS- 770
P A + FP SG AE+SP D+ R G+ G +P G L VS
Sbjct: 683 PVPIASKPFPTSG-------RAEASPNDTAGARTEMGT--------GSRVPGGSPLGVSL 727
Query: 771 -PSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGG---DSDQYVLM 826
SD + S A H PL G G KAP T + Y
Sbjct: 728 VYSDKKSAAAT----SPAPHLVAGPLLGTVG----------KAPATVTNLLVGTPGYGAP 773
Query: 827 SSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGR 886
+ P + + + A G + A S GAG + P PV P G G LG+ G
Sbjct: 774 APPAVQFIAQ-----GAPGGGTTAGSGAGAG-SGPNGPV------PLGILQPGALGKAGG 821
Query: 887 AVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAP------PLLA 940
+ + LP+LP + P P G A S PAP L
Sbjct: 822 ITQVQYI----LPTLPQQLQVAPAPAPAP---------GTKAAAPSGPAPTTSIRFTLPP 868
Query: 941 SAASSSSLLSASSPASSL-------GSGTPGTSSDSRQRSP--------LSDYMNLDFSS 985
+++ +L+A++P + + P S S ++P L + + ++
Sbjct: 869 GTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAA 928
Query: 986 PKSPKPGAPSGHPVGSLDGLLSPEASSP-----YPP-----LPPRPSASPSSSLQPPPPP 1035
P G +G P+ L+SP S P PP L P P ++PS + P P
Sbjct: 929 PSMSVRGGGAGQPL----PLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPA 984
Query: 1036 PAPG-----ELYRLPPASAVATAQGPGA---------ASSLSSDTGDNGDYTEMAFGVAA 1081
PG + LP ++ + Q G ASS + G + +A G +
Sbjct: 985 TLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTS 1044
Query: 1082 TPPQ--------------PIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPP 1127
P P+ AP + + V SP + V + AF S P
Sbjct: 1045 LGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPV--ITAFYSGS--P 1100
Query: 1128 DPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSE 1187
P A + Q + S +T+T P + P +A+ S S+
Sbjct: 1101 APTSSAPL----AQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSAT 1156
Query: 1188 GGVG----VGPGGGDEPPTSPRQLQPAPPLAPQG--RPWTPGQPGGLVGCPGSGGSPMRR 1241
G V P P +P++++ A P G G+PG P G P+R
Sbjct: 1157 AGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPG-PVRE 1215
Query: 1242 ETSAGFQNGLNYIAIDVREEPGLPPQPQPPP------------PPLPQPGDKSSWGRTRS 1289
T+ E G P P PPP PPLP P ++ RT +
Sbjct: 1216 PTA------------PESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEE----RTSA 1259
Query: 1290 LGGLISAVGVGSTGGGCGGPGPG 1312
G A S+ PG G
Sbjct: 1260 KGPETMASKFPSSSSDWRVPGQG 1282
Score = 69.7 bits (169), Expect = 2e-11
Identities = 142/542 (26%), Positives = 198/542 (36%), Gaps = 118/542 (21%)
Query: 638 GSHRSSSSNLGAD---DGYMPM---TPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQ 691
G ++ S GA +G +P+ PGA G G + +P P Q LQ
Sbjct: 787 GGGTTAGSGAGAGSGPNGPVPLGILQPGAL--GKAGGITQVQYILPTLP-------QQLQ 837
Query: 692 PRAAAAAAAAVPSAGPAGPAPTSAAGRTFP----ASGGGYKASSPAESSP-----EDSGY 742
A A A +A P+GPAPT++ T P +G A++P P +
Sbjct: 838 VAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPP 897
Query: 743 MRMWCGSKLSMEHADG--KLLPNGDYLNVS-PSDAVTTG---------TPPDFFSAALHP 790
+ S + G +LLP + ++ PS +V G +PP FS +
Sbjct: 898 PKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPP--FSVPVQN 955
Query: 791 GGEP------LRGVPGCCYSSLPRSYKAPYTCGGDSDQ--YVLMSSPVGRILEEERLEPQ 842
G +P L VP S L +P T G + Q VL+ S RI +
Sbjct: 956 GAQPPSKIIQLTPVPVSTPSGLVPPL-SPATLPGPTSQPQKVLLPSST-RITYVQSAGGH 1013
Query: 843 A-----TPGPSQAASAFGAGPTQ----------PPHPVVPSPVRPSGGRPEGFLGQRGRA 887
A +P SQA + GPT P P P+ +G P
Sbjct: 1014 ALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAP---------L 1064
Query: 888 VRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDF--GEPGARLSPP------APPLL 939
+ P ++ + +PS LPP +PG + F G P S P APP L
Sbjct: 1065 LAPGQVGVSPVPSPQ------LPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSL 1118
Query: 940 ASAASSSSLLSASS--PASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKS--PKPGAP- 994
++S+ A++ P T + S S + M +PK+ P P AP
Sbjct: 1119 VYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQ 1178
Query: 995 ------SGHPVGSLD----GLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRL 1044
+ PVGS + G P P P P R +P S L+ P PPAP L
Sbjct: 1179 KVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPET 1238
Query: 1045 ------------PPASAVATAQGPGAAS----SLSSDTGDNGDYTEMAFGVAATPPQPIA 1088
PPA +A+GP + S SSD G E G TPP P
Sbjct: 1239 WTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENR-GEPPTPPSPAP 1297
Query: 1089 AP 1090
AP
Sbjct: 1298 AP 1299
Score = 61.6 bits (148), Expect = 5e-09
Identities = 206/874 (23%), Positives = 286/874 (32%), Gaps = 116/874 (13%)
Query: 461 PPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNT 520
PP P PP P G+ S +S++ SP+ + + G +A S + +T
Sbjct: 508 PPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGST 567
Query: 521 PESIAETPPARDGGGG----GEFYGYMTMD-------RPLSHCGRSYRRVSGDAAQDLDR 569
+ PP G GG + ++ MD RP S G S AA
Sbjct: 568 AGPLRPPPP---GAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGG 624
Query: 570 GLRKRTYSLTTPARQRP-----VPQPSSASLDEYTLMRATFSGSAGRLCPSC--PASSPK 622
G +T L ++ VP + SL Y A S A + + P SS
Sbjct: 625 GNILQTLVLPPNKEEQEGGGARVPSAPAPSL-AYGAPAAPLSRPAATMVTNVVRPVSSTP 683
Query: 623 V--AYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSP 680
V A P+P G E + ++ + + G PG + G SP
Sbjct: 684 VPIASKPFPTS-GRAEASPNDTAGAR--TEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP 740
Query: 681 ASVSAPKQILQPRAAAAAAAA---VPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSP 737
A +L A A V + G PAP + A GGG A S A +
Sbjct: 741 APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800
Query: 738 EDSGYMRMWCGSKLSMEHADG-----KLLPN-GDYLNVSPSDAVTTGTPPDFFSAALHPG 791
+G + + ++ A G +LP L V+P+ A GT AA G
Sbjct: 801 GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGT-----KAAAPSG 855
Query: 792 GEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAA 851
P + R P T +P IL+ P A P +Q+
Sbjct: 856 PAPTTSI---------RFTLPPGTSTNGKVLAATAPTPGIPILQS---VPSAPPPKAQSV 903
Query: 852 SAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPP 911
S A P ++P V P + + G A +P LP + P+
Sbjct: 904 SPVQAPPPGGSAQLLPGKVLVPLAAPSMSV-RGGGAGQP-------LPLVSPPFSVPVQN 955
Query: 912 EPKSPGEYIN---IDFGEPGARLSPPAPPLLASAASSSS--LLSASS----PASSLGSGT 962
+ P + I + P + P +P L S LL +S+ S+ G
Sbjct: 956 GAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHAL 1015
Query: 963 P-GTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPL--PP 1019
P GTS S Q ++ Y S G S P G + P S+ PL P
Sbjct: 1016 PLGTSPASSQAGTVTSY-----GPTSSVALGFTSLGPSG--PAFVQPLLSAGQAPLLAPG 1068
Query: 1020 RPSASPSSSLQPPPPPPAPG-----ELYRLPPA--SAVATAQGPGAASSLSSDTGDNGDY 1072
+ SP S Q PP APG Y PA S+ AQ A SL T
Sbjct: 1069 QVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVY-TVATSTT 1127
Query: 1073 TEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRG 1132
A + PP P A P P + S T+G SL V Q P P +
Sbjct: 1128 PPAATILPKGPPAPATATPAP-TSPFPSATAGSMTYSL------VAPKAQRPSPKAPQKV 1180
Query: 1133 AKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGV 1192
I + P G +S P+ P P + +S G
Sbjct: 1181 KAAIASIPVGSFEAGASGR-PGPAPRQPLEPGPVREP-----------TAPESELEGQPT 1228
Query: 1193 GPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLN 1252
P P T + +PPL P T + + S R G +N
Sbjct: 1229 PPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLEN--- 1285
Query: 1253 YIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGR 1286
R EP PP P P P P +SS GR
Sbjct: 1286 ------RGEPPTPPSPAPAPAVAPGGSSESSSGR 1313
Score = 38.9 bits (89), Expect = 0.033
Identities = 108/457 (23%), Positives = 146/457 (31%), Gaps = 74/457 (16%)
Query: 332 PPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLS 391
P + G + S A P + AS G AGA+ RP PL
Sbjct: 1153 PSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASG---RPGPAPRQPLE 1209
Query: 392 PGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPV---AHSPPAATSPGSL 448
PGPVR P + L G+ + A P + S P+ A +A P ++
Sbjct: 1210 PGPVREPTAPESELE----GQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETM 1265
Query: 449 -----SSSS-----GHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGS------- 491
SSSS G G + PP P P P P PG S S A+G
Sbjct: 1266 ASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPA-VAPGGSSESSSGRAAGDTPERKEA 1324
Query: 492 ------------PSDPGFMSLDEYGSSPGDL-RAFCSHRSNTPESIAETPPARDGGGGGE 538
P F S+D S D F PE + +P +
Sbjct: 1325 AGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQ------- 1377
Query: 539 FYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEY 598
T R + R R+ S DLD T + +R + + SS S +
Sbjct: 1378 --SLATSPRAILGSYRKKRKNS----TDLDSAPEDPT------SPKRKMRRRSSCSSEPN 1425
Query: 599 TLMRATFSG---SAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMP 655
T A G + R ++ Y P + R+ L D G+ P
Sbjct: 1426 TPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFP 1485
Query: 656 MTPGAALAGS------GSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAG-PA 708
A + S C + + A QP A A P G A
Sbjct: 1486 SAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAA 1545
Query: 709 GPAPT-SAAG---RTFPASGGGYKASSPAESSPEDSG 741
PAPT S AG T P+S G ++P P +SG
Sbjct: 1546 APAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
Score = 37.4 bits (85), Expect = 0.097
Identities = 31/116 (26%), Positives = 40/116 (34%), Gaps = 8/116 (6%)
Query: 1016 PLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEM 1075
P P PS PS + QP P A + ++AVA + PG S + E
Sbjct: 46 PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPE- 104
Query: 1076 AFGVAATPPQPIAA-----PPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQP 1126
PP P+ P P AS G RL + +AFL P
Sbjct: 105 --SPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSP 158
Score = 35.0 bits (79), Expect = 0.48
Identities = 41/160 (25%), Positives = 58/160 (36%), Gaps = 25/160 (15%)
Query: 954 PASSLGSGTPG----TSSDSRQRSPLSDYMNLDFSSPKSPKPGA-------PSGHPVGSL 1002
PASS S G T+ + R + + + F +P P P P+ HPV S
Sbjct: 10 PASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASN 69
Query: 1003 DGLLSPEASSPYPPLPPRPSAS-----------PSSSLQPPPPPPAPGELYRLPPASAVA 1051
E+++ PP + S P S PP P E + PP +
Sbjct: 70 QSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEE 129
Query: 1052 TAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPP 1091
A GP L S+T + D AF +P + PP
Sbjct: 130 EASGPPGEPRLDSETESDHD---DAFLSIMSPEIQLPLPP 166
Score = 33.9 bits (76), Expect = 1.1
Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 25/80 (31%)
Query: 984 SSPKSPKPGAPSGHPVGSLDGLLSPEASSP--------------------YPPLPPRPSA 1023
++P PGA + PV G + A +P PPLPP P +
Sbjct: 1522 ATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPES 1581
Query: 1024 SP-----SSSLQPPPPPPAP 1038
P + QP PPPP P
Sbjct: 1582 GPGQPGWEGAPQPSPPPPGP 1601
Score = 33.1 bits (74), Expect = 1.8
Identities = 37/104 (35%), Positives = 42/104 (40%), Gaps = 16/104 (15%)
Query: 432 SMPVAHS-PPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPL---HHGPGQRPSSGSAS 487
S VAH PP T G + P PGP P PHPL G G P++
Sbjct: 77 SAAVAHERPPGGTGSADPERPPG---ATCPESPGPGP--PHPLGVVESGKGPPPTT-EEE 130
Query: 488 ASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPAR 531
ASG P +P LD S D AF S S PE PP +
Sbjct: 131 ASGPPGEP---RLDSETESDHD-DAFLSIMS--PEIQLPLPPGK 168
Score = 33.1 bits (74), Expect = 1.8
Identities = 21/58 (36%), Positives = 23/58 (39%), Gaps = 8/58 (13%)
Query: 438 SPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDP 495
SP P S SS SG + PPLP P GPGQ G+ S P P
Sbjct: 1552 SPAGGPDPTSPSSDSGTAQAA--------PPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601
Score = 32.3 bits (72), Expect = 3.1
Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 8/54 (14%)
Query: 993 APSGHPVGSLDGLLSPEASS----PYPPLPPRPSASPSS---SLQPPPPPPAPG 1039
AP+ P G D SP + S PPLPP P + P P P PP PG
Sbjct: 1548 APTPSPAGGPDPT-SPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPG 1600
Score = 31.6 bits (70), Expect = 5.3
Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 22/98 (22%)
Query: 927 PGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSP 986
PGA P PP +AA+ + SPA +P + S + Q +P P
Sbjct: 1529 PGAEAPLPVPPPTGTAAAPAP---TPSPAGGPDPTSPSSDSGTAQAAP-----------P 1574
Query: 987 KSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSAS 1024
P P + G P +G A P PP PP PS +
Sbjct: 1575 LPPPPESGPGQP--GWEG-----APQPSPP-PPGPSTA 1604
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 77.0 bits (188), Expect = 1e-13
Identities = 212/949 (22%), Positives = 297/949 (31%), Gaps = 139/949 (14%)
Query: 351 PPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLS------PGPVRAPLSRSHT 404
PP ++ + E G AAA AAA + AG P P+ L
Sbjct: 19 PPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAE 78
Query: 405 LSGGCGGRGSKVALLP-AGGALQHSRSMSMP-VAHSPPAATSPGSLSSSSGHGSGSYPPP 462
+GG GG G+ P A L++S + P A + PG S G G+ PP
Sbjct: 79 SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA--PP 136
Query: 463 PGPHPPLPHPLH---HGPGQRPSSGSASAS-------GSPSDPGFMSLDEYGSSPGDLRA 512
LP P + G+ PS+ +A+A+ G PG +L G G L
Sbjct: 137 HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG--GGLEP 194
Query: 513 FCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLR 572
+ + N + D G Y +R +Y + A RG
Sbjct: 195 YAGPQQN----------SHDHGFPNHQYNSYYPNR------SAYPPPAPAYALSSPRGGT 238
Query: 573 KRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDY 632
+ + + P +SAS + + F G P A P+
Sbjct: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--------GGPSAAGGGTPQPT 290
Query: 633 GDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQP 692
+ +S S+ GY PG +G P + P +
Sbjct: 291 ATPTLNQLLTSPSSARGYQGY----PGGDYSGG-----------PQDGGAGKGPADMASQ 335
Query: 693 RAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLS 752
AAAAAA +A G S P S GG P +P+ S M
Sbjct: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG--GGQPLARTPQPSSPMDQM------ 387
Query: 753 MEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCY-SSLPRSYK 811
GK+ P GT P G + G PG Y S P+ Y
Sbjct: 388 -----GKMRPQ-----------PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY- 430
Query: 812 APYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGP---TQPPHPVVPS 868
P T G + S +G + +++ P GPS G P Q PHP
Sbjct: 431 -PMTMQGRA------QSAMGGLSYTQQIPPYGQQGPSGYGQQ-GQTPYYNQQSPHPQQQQ 482
Query: 869 PVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYP-LPPEPKSPGEYINIDFGEP 927
P + Q +P + S P + P PP +SP Y +
Sbjct: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
Query: 928 GARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPK 987
S P P A S PA S S Q+S + Y F P+
Sbjct: 543 QHPQSQP-PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601
Query: 988 SPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPP--PPAPGELYRLP 1045
S D S +S+P + SLQ P P G + LP
Sbjct: 602 EL-----------SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650
Query: 1046 PASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGV 1105
+ A + G + S +SS G+ + + F +P P P P + V SP S
Sbjct: 651 MGTEGALSPGV-STSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP--SPVGSPASVA 707
Query: 1106 KRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSF 1165
+ S + V PP P G Q H S SS
Sbjct: 708 QSRSGPLSPAAVPG---NQMPPRPPSG--------QSDSIMHPSMNQSSIAQDRGYMQRN 756
Query: 1166 AHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQP 1225
P+ + +S R+ S G + G G Q PQG + G
Sbjct: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGS--------YQQNSMGSYGPQGGQY--GPQ 806
Query: 1226 GGLVGCPGSGGSPMRRETSAGFQNGLNYIAI--DVREEPGLPPQPQPPP 1272
GG P P SAG G+N + + +PG+PP PP
Sbjct: 807 GGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPP 855
Score = 32.3 bits (72), Expect = 3.1
Identities = 116/561 (20%), Positives = 176/561 (31%), Gaps = 105/561 (18%)
Query: 780 PPDFFSAALHPGGEPLRGVPGCCYSS------LPRSYKAPYTCGGDSDQYVLMSSPVGRI 833
PPD F+AA +P P S P+S + GGD S+P +I
Sbjct: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI 1173
Query: 834 LEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRL 893
+ + G A + Q + + P+P +G R+
Sbjct: 1174 PPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMG---------RM 1224
Query: 894 SLE-GLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPA----------------- 935
S E SM + P S G+ N G+P +R + P
Sbjct: 1225 SYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGP 1284
Query: 936 -----------PPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFS 984
P S + L S+P S + S + +Q+ D FS
Sbjct: 1285 YDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFS 1344
Query: 985 SPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELY-- 1042
+ G PSG P S + + Y P PP GE+Y
Sbjct: 1345 TQ-----GTPSGSPFPSQQTTMYQQQQQNYK--------RPMDGTYGPPAKRHEGEMYSV 1391
Query: 1043 ------------RLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAP 1090
+LPPA +Q A S D + A AAT +P P
Sbjct: 1392 PYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGP 1451
Query: 1091 PKP-----EAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRR 1145
RV++P + ++ Q+ G +QAS A+V + R
Sbjct: 1452 QNQFPFQFGRDRVSAPPGTNAQQNMPPQMMG--GPIQAS--------AEVAQQGTMWQGR 1501
Query: 1146 RHSSETFSS--TTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGD-EPPT 1202
+ +++ +T P P++ H R + + + R + EG P G +PP
Sbjct: 1502 NDMTYNYANRQSTGSAPQGPAY-HGVNR--TDEMLHTDQRANHEGS---WPSHGTRQPPY 1555
Query: 1203 SPRQLQPAPPLA---PQGRPWTPGQPGGL--VGCPGSGGSPMRRETSAGFQNGLNYIAID 1257
P P PP+ P P + V P PM TS L+
Sbjct: 1556 GPS--APVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKM 1613
Query: 1258 VREEPGLPPQ---PQPPPPPL 1275
+ P +P P P PP+
Sbjct: 1614 QKAGPPVPASHIAPAPVQPPM 1634
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 77.0 bits (188), Expect = 1e-13
Identities = 212/949 (22%), Positives = 297/949 (31%), Gaps = 139/949 (14%)
Query: 351 PPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLS------PGPVRAPLSRSHT 404
PP ++ + E G AAA AAA + AG P P+ L
Sbjct: 19 PPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAE 78
Query: 405 LSGGCGGRGSKVALLP-AGGALQHSRSMSMP-VAHSPPAATSPGSLSSSSGHGSGSYPPP 462
+GG GG G+ P A L++S + P A + PG S G G+ PP
Sbjct: 79 SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGA--PP 136
Query: 463 PGPHPPLPHPLH---HGPGQRPSSGSASAS-------GSPSDPGFMSLDEYGSSPGDLRA 512
LP P + G+ PS+ +A+A+ G PG +L G G L
Sbjct: 137 HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG--GGLEP 194
Query: 513 FCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLR 572
+ + N + D G Y +R +Y + A RG
Sbjct: 195 YAGPQQN----------SHDHGFPNHQYNSYYPNR------SAYPPPAPAYALSSPRGGT 238
Query: 573 KRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDY 632
+ + + P +SAS + + F G P A P+
Sbjct: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG--------GGPSAAGGGTPQPT 290
Query: 633 GDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQP 692
+ +S S+ GY PG +G P + P +
Sbjct: 291 ATPTLNQLLTSPSSARGYQGY----PGGDYSGG-----------PQDGGAGKGPADMASQ 335
Query: 693 RAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLS 752
AAAAAA +A G S P S GG P +P+ S M
Sbjct: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG--GGQPLARTPQPSSPMDQM------ 387
Query: 753 MEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCY-SSLPRSYK 811
GK+ P GT P G + G PG Y S P+ Y
Sbjct: 388 -----GKMRPQ-----------PYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY- 430
Query: 812 APYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGP---TQPPHPVVPS 868
P T G + S +G + +++ P GPS G P Q PHP
Sbjct: 431 -PMTMQGRA------QSAMGGLSYTQQIPPYGQQGPSGYGQQ-GQTPYYNQQSPHPQQQQ 482
Query: 869 PVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYP-LPPEPKSPGEYINIDFGEP 927
P + Q +P + S P + P PP +SP Y +
Sbjct: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
Query: 928 GARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPK 987
S P P A S PA S S Q+S + Y F P+
Sbjct: 543 QHPQSQP-PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601
Query: 988 SPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPP--PPAPGELYRLP 1045
S D S +S+P + SLQ P P G + LP
Sbjct: 602 EL-----------SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650
Query: 1046 PASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGV 1105
+ A + G + S +SS G+ + + F +P P P P + V SP S
Sbjct: 651 MGTEGALSPGV-STSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSP--SPVGSPASVA 707
Query: 1106 KRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSF 1165
+ S + V PP P G Q H S SS
Sbjct: 708 QSRSGPLSPAAVPG---NQMPPRPPSG--------QSDSIMHPSMNQSSIAQDRGYMQRN 756
Query: 1166 AHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQP 1225
P+ + +S R+ S G + G G Q PQG + G
Sbjct: 757 PQMPQYSSPQPGSALSPRQPSGGQIHTGMGS--------YQQNSMGSYGPQGGQY--GPQ 806
Query: 1226 GGLVGCPGSGGSPMRRETSAGFQNGLNYIAI--DVREEPGLPPQPQPPP 1272
GG P P SAG G+N + + +PG+PP PP
Sbjct: 807 GGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPP 855
Score = 37.0 bits (84), Expect = 0.13
Identities = 66/307 (21%), Positives = 100/307 (32%), Gaps = 34/307 (11%)
Query: 581 PARQRPVPQPSSASLDEYTLMRATFS-GSAGRLCPSCPASSPKVAYHPYPEDYGDIEIG- 638
P Q P P S + T + S G L P PAS+P P P +G
Sbjct: 1128 PKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGI 1187
Query: 639 ---------SHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQI 689
S +++ + GY P + + G S D Y M A S P
Sbjct: 1188 QDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM- 1246
Query: 690 LQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGS 749
++ P+ G P +A G G A P + P Y R+
Sbjct: 1247 --------SSGQGPNGGMGDPYSRAAG------PGLGNVAMGPRQHYPYGGPYDRVRTEP 1292
Query: 750 KLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRS 809
+ E G + N+ PS+ + P + + G +S+
Sbjct: 1293 GIGPE---GNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP 1349
Query: 810 YKAPY----TCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPV 865
+P+ T Q V +P+ R +E R P +P AGP P +
Sbjct: 1350 SGSPFPSQQTTMYQQQQQVSSPAPLPRPMEN-RTSPSKSPFLHSGMKMQKAGPPVPASHI 1408
Query: 866 VPSPVRP 872
P+PV+P
Sbjct: 1409 APAPVQP 1415
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 76.3 bits (186), Expect = 2e-13
Identities = 162/649 (24%), Positives = 212/649 (32%), Gaps = 155/649 (23%)
Query: 721 PASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLL----PNGDYLNVSPS-DAV 775
PA+G S E+ + M+ KL ME +G L P GD + P D
Sbjct: 529 PAAGADLDKIGLHSDSQEE---LWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRG 585
Query: 776 TTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILE 835
GTP G+PG P+ K GD M P+G+
Sbjct: 586 FPGTP----------------GIPGPLGHPGPQGPKGQKGSVGDPG----MEGPMGQRGR 625
Query: 836 EERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSL 895
E + P+ GP + G P P P V S G P+G G G P + L
Sbjct: 626 EGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVG-PKGSSGSPGPQGPPGPVGL 684
Query: 896 EGL---PSLPSM--HEYPL-PPEPKSPGEYINIDFGEPGAR--LSPPAPPLLASAASSSS 947
+GL LP + + P+ PP PK D GE G R P L A
Sbjct: 685 QGLRGEVGLPGVKGDKGPMGPPGPKG-------DQGEKGPRGLTGEPGMRGLPGAVGEPG 737
Query: 948 LLSASSPASSLG-------SGTPGTSSDSRQRSPLSDYMNLDFSSPKSPK--PGAP---- 994
A PA G G G P D + P+ P+ PG P
Sbjct: 738 AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPG 797
Query: 995 -SGHPVGSLDGLLSPEASS----PYPPLPPRPSASPSSSLQPPPPPPAPGEL--YRLPPA 1047
G P G+ +++ E SS P PP PP ++ PP PP APG LP
Sbjct: 798 IKGEP-GAPGKIVTSEGSSMLTVPGPPGPP-------GAMGPPGPPGAPGPAGPAGLPGH 849
Query: 1048 SAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKR 1107
V QGP G G G P + + PP P +
Sbjct: 850 QEVLNLQGPPGP---PGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGS----------- 895
Query: 1108 LSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAH 1167
+S E FL P G K + P G R H E
Sbjct: 896 -----FLSNSETFLSGPPGPPGPPGPKGDQGPP--GPRGHQGE----------------- 931
Query: 1168 NPKRHNSASVENVSLRKSSEGGVGV-GPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPG 1226
+ S SS G+ + GP G P P P+G PG PG
Sbjct: 932 -------QGLPGFSTSGSSSFGLNLQGPPG------------PPGPQGPKGDKGDPGVPG 972
Query: 1227 --GLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDK--- 1281
G+ P GGS +S + +G P PP P PP + G +
Sbjct: 973 ALGIPSGPSEGGS-----SSTMYVSG-----------PPGPPGPPGPPGSISSSGQEIQQ 1016
Query: 1282 --SSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYASIDFLSH 1328
S + ++ S+ +S GV G G PGP T+ + SH
Sbjct: 1017 YISEYMQSDSIRSYLS--GVQGPPGPPGPPGPVTTITGETFDYSELASH 1063
Score = 68.9 bits (167), Expect = 3e-11
Identities = 140/537 (26%), Positives = 192/537 (35%), Gaps = 104/537 (19%)
Query: 827 SSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGR 886
+ P G +E L Q PGP GP PP P +P P P G EG G G
Sbjct: 841 AGPAGLPGHQEVLNLQGPPGPP--------GPRGPPGPSIPGPPGPRGPPGEGLPGPPGP 892
Query: 887 A---VRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGAR--LSPPAPPLLAS 941
+ + L G P P PP PK D G PG R P ++
Sbjct: 893 PGSFLSNSETFLSGPPGPPG------PPGPKG-------DQGPPGPRGHQGEQGLPGFST 939
Query: 942 AASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPK--PGAPS--GH 997
+ SSS L+ P G PG PK K PG P G
Sbjct: 940 SGSSSFGLNLQGPP-----GPPGPQG------------------PKGDKGDPGVPGALGI 976
Query: 998 PVGSLDGLLSPE---ASSPYPPLPPRPSASPSSS---LQPPPPPPAPGELYRLPPASAVA 1051
P G +G S + P PP PP P S SSS +Q + R +
Sbjct: 977 PSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQG 1036
Query: 1052 TAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLM 1111
PG +++ TG+ DY+E+A V + + +S S L+++
Sbjct: 1037 PPGPPGPPGPVTTITGETFDYSELASHVVS-----YLRTSGYGVSLFSSSISSEDILAVL 1091
Query: 1112 EQVSGVEAFLQA--------SQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSP 1163
++ V +L+ PP ++ D R S + S++ ++ P
Sbjct: 1092 QR-DDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILS--YMSSSGISIGLP 1148
Query: 1164 SFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPP-------LAPQ 1216
P ++ E +SL + SE VGP G PP P + + L
Sbjct: 1149 GPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTA 1208
Query: 1217 GRPWTPGQPG-----GLVGCPGSGGS--PMRRETSAGFQNGL-NYIAI-DVRE----EPG 1263
G + PG PG G G PG G+ E S F++ L +Y+ DVR PG
Sbjct: 1209 GLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268
Query: 1264 LPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGST--------GGGCGGPGPG 1312
PP PQ PP +S R S S+V GS+ GGG G G G
Sbjct: 1269 -PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAG 1324
Score = 58.9 bits (141), Expect = 3e-08
Identities = 129/546 (23%), Positives = 179/546 (32%), Gaps = 63/546 (11%)
Query: 792 GEP-LRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQA 850
GEP +RG+PG + P G D Q P G + PGPS
Sbjct: 722 GEPGMRGLPGAVGEPGAKGAMGP--AGPDGHQ-----GPRGEQGLTGMPGIRGPPGPSGD 774
Query: 851 ASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLP 910
G Q P + +P RP G G+ + + L++ G P P P P
Sbjct: 775 PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP 834
Query: 911 PEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSR 970
P P + + L P P S+ P G G PG
Sbjct: 835 PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGP-- 892
Query: 971 QRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQ 1030
S LS+ P P P P G G + P S+S +LQ
Sbjct: 893 PGSFLSNSETFLSGPPGPPGPPGPKGDQ--GPPGPRGHQGEQGLPGFSTSGSSSFGLNLQ 950
Query: 1031 PPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAP 1090
PP PP P PG +L +G + + V+ P P P
Sbjct: 951 GPPGPPG--------PQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPP--GP 1000
Query: 1091 PKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQ-PPDPHRGAKVIRADPQGGRRRHSS 1149
P P + +S + +S Q + ++L Q PP P P G +
Sbjct: 1001 PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGP--------PGPPGPVTTITG 1052
Query: 1150 ETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQP 1209
ETF + + V R + V S SSE + V RQ
Sbjct: 1053 ETFDYSELASHVVSYL-----RTSGYGVSLFSSSISSEDILAV------LQRDDVRQYLR 1101
Query: 1210 APPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQ 1269
+ P+G P PG G GS S E S+ + ++ I + GLP P
Sbjct: 1102 QYLMGPRGPPGPPGASG-----DGSLLSLDYAELSSRILSYMSSSGISI----GLPGPPG 1152
Query: 1270 PPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYASI--DFLS 1327
PP P + S R G++ G G PGP + P N ++SI + LS
Sbjct: 1153 PPGLPGTSYEELLSLLRGSEFRGIV---------GPPGPPGPPGI-PGNVWSSISVEDLS 1202
Query: 1328 HHLKEA 1333
+L A
Sbjct: 1203 SYLHTA 1208
Score = 50.1 bits (118), Expect = 1e-05
Identities = 210/947 (22%), Positives = 301/947 (31%), Gaps = 185/947 (19%)
Query: 387 GSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAG--GAL-QHSRSMSM-PVAHSPPAA 442
G+P PGP+ P G G +G K ++ G G + Q R M P + P
Sbjct: 588 GTPGIPGPLGHP--------GPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGP-- 637
Query: 443 TSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDE 502
PGS +G PGPH P P GP + SSGS G P G L
Sbjct: 638 --PGSGEKGERGAAGE----PGPHGPPGVPGSVGP--KGSSGSPGPQGPPGPVGLQGLRG 689
Query: 503 YGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMD-----RPLSHCGRSYR 557
PG + PP G G + +T + P + +
Sbjct: 690 EVGLPG----------VKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAK 739
Query: 558 RVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCP 617
G A D +G R P + P P PS G G P P
Sbjct: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGP-PGPSGD------------PGKPGLTGPQGP 786
Query: 618 ASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMP 677
P P + E G+ ++ G+ +P PG A G + P
Sbjct: 787 QGLPGTPGRPGIKG----EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPG--P 840
Query: 678 MSPASVSAPKQILQPRAAAAAAAAVPSAGPAG-PAPTSAAGRTFPASGGGYKASSPAESS 736
PA + +++L + GP G P P G + P G P E
Sbjct: 841 AGPAGLPGHQEVLNLQ------------GPPGPPGPRGPPGPSIPGPPG--PRGPPGEGL 886
Query: 737 PEDSGYMRMWCGSKLSMEHA--------DGKLLPNGDYLNVSPSDAVTTGTPPDFFSAAL 788
P G GS LS G P GD P P F ++
Sbjct: 887 PGPPGPP----GSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942
Query: 789 HPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPS 848
G L+G PG P + P GD + P GPS
Sbjct: 943 SSFGLNLQGPPG------PPGPQGPKGDKGDPGVPGALGIP---------------SGPS 981
Query: 849 QAASA---FGAGPTQPPHPV-VPSPVRPSGGRPEGFLGQ--RGRAVRPTRLSLEGLPSLP 902
+ S+ + +GP PP P P + SG + ++ + + ++R ++G P P
Sbjct: 982 EGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPP 1041
Query: 903 SMHEYPLPPEPKSPGEYINIDFGEPGA------RLSPPAPPLLASAASSSSLLSA----- 951
PP P + D+ E + R S L +S+ SS +L+
Sbjct: 1042 G------PPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDD 1095
Query: 952 ---------------SSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSG 996
P + G G+ + + S + YM+ S P P P G
Sbjct: 1096 VRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPG 1155
Query: 997 HPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGP 1056
P S + LLS S + + P PP PP PG ++ +++
Sbjct: 1156 LPGTSYEELLSLLRGSEFRGIVGPPG--------PPGPPGIPGNVWSSISVEDLSSYLHT 1207
Query: 1057 GAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEA-ARVASPTSGVKRLSLMEQVS 1115
S + G G PP P P A A A+ S R L+ ++
Sbjct: 1208 AGLSFIPGPPGPPG------------PPGPRGPPGVSGALATYAAENSDSFRSELISYLT 1255
Query: 1116 GVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPK-RHNS 1174
+ PP P PQG S S+ + + S S +H+ R S
Sbjct: 1256 SPDVRSFIVGPPGP--------PGPQG--PPGDSRLLSTDASHSRGSSSSSHSSSVRRGS 1305
Query: 1175 ASVENVSLRKSSEGGVGV----GPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVG 1230
+ ++S G +G G GD P + P GGL+G
Sbjct: 1306 SYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYG-TDIGPGGGYGAAAEGGMYAGNGGLLG 1364
Query: 1231 CPGSGG-----SPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPP 1272
+G +R S Q L +A V+ PG P PQ PP
Sbjct: 1365 ADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPG-QPGPQGPP 1410
Score = 34.7 bits (78), Expect = 0.63
Identities = 46/171 (26%), Positives = 58/171 (33%), Gaps = 40/171 (23%)
Query: 333 PSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAA-GARPVSVAGSPLS 391
P + GL L TP R +G+ GA + G+ ++V G P
Sbjct: 775 PGKPGLTGPQGPQGLPGTPG---------RPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP 825
Query: 392 PGPVRAPLSRSHTLSGGCGGRGSKVALLPAG--GALQHSRSMSMPVAHSPPAATSPGSLS 449
PG + P G G G PAG G H +++ PP P
Sbjct: 826 PGAMGPP--------GPPGAPG------PAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-- 869
Query: 450 SSSGHGSGSYPPPPGPHPP----LPHPLHHGPGQRPSSGSASASGSPSDPG 496
S P PPGP P LP P PG S+ SG P PG
Sbjct: 870 -------PSIPGPPGPRGPPGEGLPGP-PGPPGSFLSNSETFLSGPPGPPG 912
Score = 33.5 bits (75), Expect = 1.4
Identities = 38/130 (29%), Positives = 44/130 (33%), Gaps = 19/130 (14%)
Query: 379 GARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHS 438
G R G P PGP + LS S T G G P + + P H
Sbjct: 877 GPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGP-------PGPPGPKGDQGPPGPRGHQ 929
Query: 439 PPAATSPGSLSSSSGHGSGSYPPP--PGPHPP--------LPHPLH--HGPGQRPSSGSA 486
S S SS G PP PGP P +P L GP + SS +
Sbjct: 930 GEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTM 989
Query: 487 SASGSPSDPG 496
SG P PG
Sbjct: 990 YVSGPPGPPG 999
Score = 32.0 bits (71), Expect = 4.1
Identities = 44/175 (25%), Positives = 54/175 (30%), Gaps = 34/175 (19%)
Query: 333 PSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPV-SVAGSPLS 391
P G + S S+ P G G A A G + V ++ G P
Sbjct: 802 PGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGP 861
Query: 392 PGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSS 451
PGP P ++ G G RG P G L PP PGS S+
Sbjct: 862 PGPRGPP---GPSIPGPPGPRG------PPGEGLP-----------GPPGP--PGSFLSN 899
Query: 452 SGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSS 506
S P PPGP PG + G G + G GSS
Sbjct: 900 SETFLSGPPGPPGP-----------PGPKGDQGPPGPRGHQGEQGLPGFSTSGSS 943
Score = 30.8 bits (68), Expect = 9.1
Identities = 18/52 (34%), Positives = 21/52 (40%), Gaps = 1/52 (1%)
Query: 446 GSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGP-GQRPSSGSASASGSPSDPG 496
G + S G +P PG PL HP GP GQ+ S G G G
Sbjct: 573 GDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 75.5 bits (184), Expect = 3e-13
Identities = 117/478 (24%), Positives = 169/478 (35%), Gaps = 89/478 (18%)
Query: 807 PRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVV 866
PR+ + G +V+ SP G G AA A GA P P P
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAG------------AAGAGPAAPAEGA-PGAAPEPPP 91
Query: 867 PSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGE 926
RP GG P QR P R + P+ P+ P PPE S G +
Sbjct: 92 AGRARPGGGGP-----QRPGPPSPRRPLVPAGPAPPAAKLRP-PPEG-SAGSCAPVPAAA 144
Query: 927 PGARLSPPAPPLLASAASSSSLLSASSPASSLGSGT-----------PGTSSDSRQRSPL 975
A PAP A A ++L + + P G G PG + + L
Sbjct: 145 AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204
Query: 976 -------SDYMNLDFSSPKS----PKPGAPSG--HPVGSLDGLLSPEASSPYPPLPPRPS 1022
+ ++L + P + PKP AP + P ++P PP P P+
Sbjct: 205 LNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA 264
Query: 1023 ASPSSSLQPPPPPPAPGELYR--------------LPPASAV----------ATAQGPGA 1058
A ++ PPPPPPAP L R +PP +A A A G
Sbjct: 265 APAAA---PPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG 321
Query: 1059 ASSLSSDTGDNGDYTEMAFGVAATPPQPI--AAPPKPEAARVASPTSGVKRLSLMEQVSG 1116
+ +S G A GV A P+ + AAPP + + P S + + + G
Sbjct: 322 PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQG 381
Query: 1117 VEAFLQASQPPDPHRGAKVIR----ADPQGGRRRHSSETFSSTTTVTP--VSPSFAHNPK 1170
A PP P + + A Q R ++ T T+TP ++P P+
Sbjct: 382 ALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQ 441
Query: 1171 RHNSASVENVSLR------KSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTP 1222
N +++N L +S G + + P + QP +AP RP TP
Sbjct: 442 --NPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAP--RPATP 495
Score = 55.8 bits (133), Expect = 3e-07
Identities = 183/819 (22%), Positives = 265/819 (32%), Gaps = 149/819 (18%)
Query: 322 ARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAAGAR 381
A HHHL P + + + + PA + A G A A AR
Sbjct: 37 AAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRAR 96
Query: 382 PVSVAGSPLSPGP--------VRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSM 433
P G P PGP P + L G A +PA A+
Sbjct: 97 P--GGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--- 151
Query: 434 PVAHSPPAATSPGSLSSSSGHGSGSYP-PPPGPHPPLPHPLHHGPGQRPSSGSASASGSP 492
P P P +L++ +G G G P P PGP P P GPG + ++A +
Sbjct: 152 PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP----AGPGAAQTLNGSAALLNS 207
Query: 493 SDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHC 552
++ + P L + P ++ +TPP F G P +
Sbjct: 208 HHAAAPAVSLVNNGPAALLPL--PKPAAPGTVIQTPP---------FVGAAAPPAPAA-- 254
Query: 553 GRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRL 612
S AA + PA P P P+ A TL R
Sbjct: 255 ------PSPPAAP-----------APAAPAAAPPPPPPAPA-----TLARP--------- 283
Query: 613 CPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRS 672
P PA P A P + + + GA P G A SG +
Sbjct: 284 -PGHPAGPPTAAPAVPPP--------AAAQNGGSAGAAPAPAPAAGGPA-GVSGQPGPGA 333
Query: 673 DDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSP 732
P +PK+++Q AA AA + ++GPA A + G T + SP
Sbjct: 334 AAAAPAPGVKAESPKRVVQ--AAPPAAQTLAASGPASTAASMVIGPTMQGA-----LPSP 386
Query: 733 AESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGG 792
A P G LP G V+ S + T A L
Sbjct: 387 AAVPPPAPG---------------TPTGLPKGAAGAVTQSLSRTPTATTSGIRATL---- 427
Query: 793 EPLRGVPGCCYSSLPRSYKAPYTCGGDS--DQYVLMSSPVGRILEEERLEPQATPGPSQA 850
P LP+ + P VL+ S G++L + PQ QA
Sbjct: 428 -----TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLL----MIPQQALAQMQA 478
Query: 851 ASAFGAGPTQPPHPVVPS---PVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEY 907
+ T P P P+ PV+ S + G R V PT + + + ++
Sbjct: 479 QAHAQPQTTMAPRPATPTSAPPVQISTVQAPG-TPIIARQVTPTTIIKQVSQAQTTVQ-- 535
Query: 908 PLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSS 967
P +SPG + G S + + ++ A++ +S + T +
Sbjct: 536 PSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSS---AATETMEN 592
Query: 968 DSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGS-LDGLLSPE----------ASSPYP- 1015
+ ++ LS + L S +S + A V + LDG + E SSP P
Sbjct: 593 VKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPY 652
Query: 1016 -------------PLPPRPSASPSSSLQPPPPP--PAPGELYRLPPASAVATAQGPGAA- 1059
L P +A S Q PPPP A L + +S+V G AA
Sbjct: 653 LVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAAT 712
Query: 1060 --SSLSSDTGDNGDYTEMAFGVAATP-PQPIAAPPKPEA 1095
S+L T++ G P P I PPKP A
Sbjct: 713 VTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGA 751
Score = 51.2 bits (121), Expect = 7e-06
Identities = 87/390 (22%), Positives = 121/390 (31%), Gaps = 96/390 (24%)
Query: 931 LSPPAPPLLASAASS-SSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSP 989
L+P P + A+AA + + + + SPA + G+G P +P
Sbjct: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAG------------------------PAAP 78
Query: 990 KPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASA 1049
GAP P G P P P PP SP L P P P +L P SA
Sbjct: 79 AEGAPGAAPEPPPAGRARPGGGGPQRPGPP----SPRRPLVPAGPAPPAAKLRPPPEGSA 134
Query: 1050 VATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLS 1109
+ A P AA+ VAA P A P KP + +G
Sbjct: 135 GSCAPVPAAAA------------------VAAGPEPAPAGPAKPAGPAALAARAG----- 171
Query: 1110 LMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNP 1169
P P G P G +++T + + + + A
Sbjct: 172 -------------PGPGPGPGPGPGPGPGKPAGPG---AAQTLNGSAALLNSHHAAAPAV 215
Query: 1170 KRHNSASVENVSLRKSSEGG--VGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGG 1227
N+ + L K + G + P G P +P P+PP AP P P
Sbjct: 216 SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA--PSPPAAP-----APAAPAA 268
Query: 1228 LVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRT 1287
P + + R PG P P P +P P + G
Sbjct: 269 APPPPPPAPATLARP-------------------PGHPAGPPTAAPAVPPPAAAQNGGSA 309
Query: 1288 RSLGGLISAVGVGSTGGGCGGPGPGALPPA 1317
+ A G + G GPG A PA
Sbjct: 310 GAAPAPAPAAGGPAGVSGQPGPGAAAAAPA 339
Score = 43.5 bits (101), Expect = 0.001
Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 31/230 (13%)
Query: 302 PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLA---ATPPAAKCSS 358
P +++ G P P RR LV P+ R + A A PAA +
Sbjct: 91 PAGRARPGGGGPQRP-GPPSPRRP--LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147
Query: 359 CRVRTASEGDG---GAAAGAAAAGARPVSVAGSPLSPGPVR-APLSRSHTLSGGCGGRGS 414
A G G AA AA AG P G PGP + A + TL+G S
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 415 KVALLPAGGALQHSRSMSMPV-----------------AHSPPAATSPGSLSSSSGHGSG 457
A PA + + + +P+ A +PPA +P ++ +
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267
Query: 458 SYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSP 507
+ PPPP PP P L PG P+ +A P + G++P
Sbjct: 268 AAPPPP---PPAPATLARPPG-HPAGPPTAAPAVPPPAAAQNGGSAGAAP 313
Score = 31.6 bits (70), Expect = 5.3
Identities = 37/131 (28%), Positives = 42/131 (32%), Gaps = 34/131 (25%)
Query: 1194 PGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCP--GSGGSPMRRETSAGFQNGL 1251
PGGG P P P PL P G P P + P GS GS +A G
Sbjct: 97 PGGGG--PQRPGPPSPRRPLVPAG----PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAG- 149
Query: 1252 NYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGP 1311
P+P P P P L + G G G GPGP
Sbjct: 150 --------------PEPAPAGPAKPA-----------GPAALAARAGPGPGPGPGPGPGP 184
Query: 1312 GALPPANTYAS 1322
G PA A+
Sbjct: 185 GPGKPAGPGAA 195
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 73.6 bits (179), Expect = 1e-12
Identities = 237/1007 (23%), Positives = 296/1007 (29%), Gaps = 215/1007 (21%)
Query: 367 GDGGAAAGAAAAGARPVSVA-GSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGAL 425
G+ G AAGAR A GS PGP P + +G G G+K + PAG
Sbjct: 306 GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT-----AGFPGSPGAKGEVGPAGSPG 360
Query: 426 QHS----RSMSMPVAHS----PPAATSPGSLSSSSGHGS---GSYPPPPG----PHPPLP 470
+ R P H+ PP PG S G G P PG PP P
Sbjct: 361 SNGAPGQRGEPGPQGHAGAQGPPGP--PGINGSPGGKGEMGPAGIPGAPGLMGARGPPGP 418
Query: 471 HPLHHGPGQRPSSGSASASGS---------------PSDPGFMSLDEYGSSPGDLRAFCS 515
+ PG R +G +G+ P PG D SPG+ A
Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA--- 475
Query: 516 HRSNTPESIAE------TPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDR 569
+ P + E PA G GE P R G
Sbjct: 476 --NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533
Query: 570 GLRKRTYSLTTPARQ-RPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPY 628
G+R S P +P P S SG G PS P P V P
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGE-----------SGRPGPPGPSGPRGQPGVMGFPG 582
Query: 629 PEDYGDIEIGSHRSSSSN--LGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAP 686
P+ G+ + N G G P P +G P P
Sbjct: 583 PK-------GNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG-------PPGPTGPGGD 628
Query: 687 KQILQPRAAAAAAAAVPSAGPAG-------PAPTSAAGRTFPASGGGYKASSPAESSPED 739
K P + GP G P P AG A GG A +P E P
Sbjct: 629 KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP-GAPGGKGDAGAPGERGPP- 686
Query: 740 SGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVP 799
+ A G G P PP AA PG L+G+P
Sbjct: 687 ------------GLAGAPGL---RGGAGPPGPEGGKGAAGPPGPPGAAGTPG---LQGMP 728
Query: 800 GCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPT 859
G GG + SP + + E P A P + GP
Sbjct: 729 G--------------ERGG-------LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767
Query: 860 QPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEY 919
PP P + GG P G G G P G P P +PG+
Sbjct: 768 GPPGPAGQPGDKGEGGAP-GLPGIAGPRGSPGERGETGPPGPAGF--------PGAPGQN 818
Query: 920 INIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYM 979
GEPG + AP A P S +G PG +R
Sbjct: 819 -----GEPGGKGERGAP---GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERG------ 864
Query: 980 NLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPG 1039
PG P GL P S+ P PP PS SP PP P
Sbjct: 865 ----------SPGGPGAAGFPGARGLPGPPGSNGNPG-PPGPSGSPGKD-----GPPGPA 908
Query: 1040 ELYRLPPASAVATAQGPGAASSLSSDTGDNG-DYTEMAFGVAA-TPPQPIAAPPKPEAAR 1097
P + V+ +G G G G+A T + +A PP R
Sbjct: 909 GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPR 968
Query: 1098 VASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTT 1157
+ GVK S +G+ PP PQG
Sbjct: 969 GSPGPQGVKGESGKPGANGLSG---ERGPP-----------GPQG--------------- 999
Query: 1158 VTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVG-VGPGGGDEPPTSPRQLQPAPPLAPQ 1216
P A P R + + + R S GG G G G P +P P P+ P
Sbjct: 1000 -LPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPA 1058
Query: 1217 GRPWTPGQ--PGGLVGCPGSGGS--------PMRRETSAGFQNGLNYIAIDVREEPGLPP 1266
G+ G+ P G G PG GS P + G + A ++ G P
Sbjct: 1059 GKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG-----AAGIKGHRGFPG 1113
Query: 1267 QPQPPPPPLPQPGDKSSWGRTRSLG--GLISAVGVGSTGGGCGGPGP 1311
P P P P G + + G G G + G G G PGP
Sbjct: 1114 NPGAPGSPGP-AGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGP 1159
Score = 69.7 bits (169), Expect = 2e-11
Identities = 230/986 (23%), Positives = 276/986 (27%), Gaps = 269/986 (27%)
Query: 362 RTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPA 421
+ S G+ GA AAG R P P + G G RG+ P
Sbjct: 466 KDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE-------KGPAGERGAPGPAGPR 518
Query: 422 GGALQHSRS--------MSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPL 473
G A + R MP SP S G G P PPGP P P
Sbjct: 519 GAAGEPGRDGVPGGPGMRGMP--GSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPG 576
Query: 474 HHG-PGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARD 532
G PG + + G+ +G PG PG + P+ PP
Sbjct: 577 VMGFPGPKGNDGAPGKNGERGGPG---------GPGPQGPPGKNGETGPQG----PPGPT 623
Query: 533 GGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSS 592
G GG + GD +GL+ + P
Sbjct: 624 GPGGDK----------------------GDTGPPGPQGLQGLPGTGGPPGE--------- 652
Query: 593 ASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDG 652
+G G P A +P P GD R GA
Sbjct: 653 -------------NGKPGEPGPKGDAGAPGA-----PGGKGDAGAPGERGPPGLAGAPGL 694
Query: 653 YMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAG---PAG 709
P G G+ P P + P P + P P G
Sbjct: 695 RGGAGPPGPEGGKGAAG------PPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748
Query: 710 PAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNV 769
P G+ P G P D G G + G P G
Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE-----GGAPGLPGIAG---PRG----- 795
Query: 770 SPSDAVTTGTP-PDFFSAAL----HPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
SP + TG P P F A PGG+ RG PG
Sbjct: 796 SPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG------------------------ 831
Query: 825 LMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRP--EGFLG 882
E+ P GP G+GP PP P R S G P GF G
Sbjct: 832 ----------EKGEGGPPGVAGPPG-----GSGPAGPPGPQGVKGERGSPGGPGAAGFPG 876
Query: 883 QRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASA 942
R GLP P + P PP P G PG + PP P A
Sbjct: 877 AR------------GLPGPPGSNGNPGPPGPS----------GSPG-KDGPPGPAGNTGA 913
Query: 943 ASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSL 1002
S + S P +G PG + P PGAP P+G +
Sbjct: 914 PGSPGV---SGPKGD--AGQPGEKGSPGAQGP----------------PGAPG--PLG-I 949
Query: 1003 DGLLSPEASSPYPPLP-PRPSASPSSSLQPPPPPPAPG-ELYRLPPA-----SAVATAQG 1055
G+ + P +P PR S P P A G R PP TA
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009
Query: 1056 PGAASSLSSD--------TGDNGDYTEMAF-GVAATPPQPIAAPPKPEAARVASPTSGVK 1106
PG + SD G GD E G P P PP P S G
Sbjct: 1010 PGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP--GPPGPVGPAGKSGDRG-- 1065
Query: 1107 RLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFA 1166
A + P RGA PQ G R ET F
Sbjct: 1066 --------ESGPAGPAGAPGPAGSRGA----PGPQ-GPRGDKGETGERGAAGIKGHRGFP 1112
Query: 1167 HNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPG 1226
NP S +G +G PG P PR P P P G+ T G PG
Sbjct: 1113 GNPGAPGSPG------PAGQQGAIG-SPG-----PAGPR--GPVGPSGPPGKDGTSGHPG 1158
Query: 1227 GLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPP-PPPLPQPGDKSSWG 1285
+G PG G+ R + PG P QP PP PP P P
Sbjct: 1159 P-IGPPGPRGNRGERGSEG---------------SPGHPGQPGPPGPPGAPGP------- 1195
Query: 1286 RTRSLGGLISAVGVGSTGGGCGGPGP 1311
GG+ +A G G GG P
Sbjct: 1196 ---CCGGVGAAAIAGIGGEKAGGFAP 1218
Score = 69.3 bits (168), Expect = 2e-11
Identities = 217/920 (23%), Positives = 274/920 (29%), Gaps = 151/920 (16%)
Query: 455 GSGSYPPPPGP-----HPPLP-HPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPG 508
G P PPGP HP P P + GP P G A SG P PG + G
Sbjct: 174 GPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEP--GQAGPSGPPGPPGAIGPSGPAGKDG 231
Query: 509 DLRAFCSHRSNTP-ESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDL 567
+ S R P E PP G G G+ M GR+ G+ +
Sbjct: 232 E-----SGRPGRPGERGLPGPPGIKGPAG--IPGFPGMKGHRGFDGRN-----GEKGETG 279
Query: 568 DRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHP 627
GL+ G G P P +P P
Sbjct: 280 APGLKGEN----------------------------GLPGENGAPGPMGPRGAPGERGRP 311
Query: 628 YPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPK 687
G R + G+D P P GS + + SP S AP
Sbjct: 312 -----GLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366
Query: 688 QILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGY----- 742
Q +P A A P P G PA G A P +G
Sbjct: 367 QRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG 426
Query: 743 MRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAAL--HPGGEPLRGVPG 800
+R G A G+ P G+ +A G P PG G+PG
Sbjct: 427 LRGGAGEP-GKNGAKGEPGPRGE-----RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPG 480
Query: 801 CCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFG----- 855
++ P + P G E+ + PGP+ A G
Sbjct: 481 AAGERGAPGFRGP-------------AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527
Query: 856 ---AGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPP- 911
GP P SP P G G +G + RP G P + +P P
Sbjct: 528 GVPGGPGMRGMP--GSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG 585
Query: 912 EPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLG-SGTPGTSSDSR 970
+PG+ N + G PG P PP + P G +G PG
Sbjct: 586 NDGAPGK--NGERGGPGGP-GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPG--PQGL 640
Query: 971 QRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQ 1030
Q P + + P P P +G P G+ G +A +P PP + +P
Sbjct: 641 QGLPGTGGPPGENGKPGEPGPKGDAGAP-GAPGG--KGDAGAPGERGPPGLAGAPGLRGG 697
Query: 1031 PPPPPPAPGELYRLPP----ASAVATAQG-PGAASSLSSDTGDNGDYTEM----AFGVAA 1081
PP P G+ PP A+ QG PG L S G GD E A GV
Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS-PGPKGDKGEPGGPGADGVPG 756
Query: 1082 T-----PPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDP--HRGAK 1134
P PI PP P G L + G + PP P GA
Sbjct: 757 KDGPRGPTGPI-GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAP 815
Query: 1135 VIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVG- 1193
+P G R + P P + V + S GG G
Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPA--GPPGPQGVKGERGSPGGPGAAG 873
Query: 1194 -PGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPG--GLVGCPGSGG-SPMRRETSAGFQN 1249
PG P P PP P G P G PG G G PGS G S + + +
Sbjct: 874 FPGARGLPGPPGSNGNPGPP-GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK 932
Query: 1250 GLNYIAIDVREEPGLPPQPQPPPP--------------PLPQPGDKSSWGRTRSLGGLIS 1295
G PG P P P P PG + S G + + G
Sbjct: 933 G----------SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG-PQGVKGESG 981
Query: 1296 AVGVGSTGGGCGGPGPGALP 1315
G G G PGP LP
Sbjct: 982 KPGANGLSGERGPPGPQGLP 1001
Score = 67.0 bits (162), Expect = 1e-10
Identities = 235/1036 (22%), Positives = 286/1036 (27%), Gaps = 189/1036 (18%)
Query: 387 GSPLSPGPVR------------APLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMP 434
GSP SPGP +P S+ + G + GG + P
Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSG----------VAVGGLAGYPGPAGPP 179
Query: 435 VAHSPPAATS-PGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGP-------GQRPSSGSA 486
PP + PGS S G P GP P P GP G+ G
Sbjct: 180 GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP 239
Query: 487 SASGSPSDPGFMSLDEYGSSPG--DLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMT 544
G P PG PG R F E+ A P G G G
Sbjct: 240 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGA---PGLKGENG--LPGENG 294
Query: 545 MDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRAT 604
P+ G R G G R + + + P P +A
Sbjct: 295 APGPMGPRGAPGER--GRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG---------- 342
Query: 605 FSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAG 664
F GS G PA SP + P G+ H + P PG +
Sbjct: 343 FPGSPGAKGEVGPAGSP--GSNGAPGQRGEPGPQGHAGAQGP--------PGPPGINGSP 392
Query: 665 SGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAG-------------PA 711
G G M PA + ++ R A A + G G P
Sbjct: 393 GGKGE--------MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG 444
Query: 712 PTSAAGRTFPASGGGYKASSPAESSPEDSGYMRM-WCGSKLSMEHADGKLLPNGDYLNVS 770
P G G K + SP + G + + G PNG
Sbjct: 445 PRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKG 504
Query: 771 PSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPV 830
P+ P AA PG + + G PG +P S P + G P
Sbjct: 505 PAGERGAPGPAGPRGAAGEPGRDGVPGGPGM--RGMPGSPGGPGSDG--------KPGPP 554
Query: 831 GRILEEERLEPQATPGPSQAASAFG-AGPT----------QPPHPVVPSPVRPSGGR--- 876
G E R P GP G GP + P P P P G
Sbjct: 555 GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET 614
Query: 877 -------PEGFLGQRGRAVRPTRLSLEGLPSL---PSMHEYPLPPEPK-------SPGEY 919
P G G +G P L+GLP P + P P PK +PG
Sbjct: 615 GPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG- 673
Query: 920 INIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGS----GTPGTSSDSRQRSPL 975
D G PG R PP LA A P G+ G PG + +
Sbjct: 674 -KGDAGAPGER----GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMP 728
Query: 976 SDYMNLDFSSPKSPK--PGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPP 1033
+ L PK K PG P V DG P P PP P+ P +
Sbjct: 729 GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG----PIGPPGPAGQPGDKGEGGA 784
Query: 1034 PP--------PAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQ 1085
P +PGE P PG G+ G E G P
Sbjct: 785 PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE-PGGKGERGAPGEKGEG----GPP 839
Query: 1086 PIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRR 1145
+A PP GVK G F A P P G
Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSP 899
Query: 1146 RHSSETFSSTTTVTPVSPSF------AHNPKRHNSASVENVSLRKSSEGGVGV-GPGGGD 1198
+ T P SP A P S + G G+ G G
Sbjct: 900 GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLA 959
Query: 1199 EPPTSPRQLQPAPPLAPQGRPWTPGQ-----------PGGLVGCPGSGGSPMR------- 1240
PP P P +G PG P GL G G+ G P R
Sbjct: 960 GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019
Query: 1241 ----RETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLP-QPGDKSSWGRTRSLGGLIS 1295
R+ S G + PG P P P PP P P KS R G
Sbjct: 1020 GLPGRDGSPGGKGDRG-----ENGSPGAPGAPGHPGPPGPVGPAGKSG---DRGESGPAG 1071
Query: 1296 AVGVGSTGGGCGGPGP 1311
G G G PGP
Sbjct: 1072 PAGAPGPAGSRGAPGP 1087
Score = 57.0 bits (136), Expect = 1e-07
Identities = 125/556 (22%), Positives = 160/556 (28%), Gaps = 131/556 (23%)
Query: 860 QPPHPVVPSPVRPSGGR-PEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPE-----P 913
QPP +P RP G+ P+G G G P R G+P P P PP P
Sbjct: 90 QPP----TAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCP 145
Query: 914 KSPGEY--------------INIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLG 959
P Y + G PG PP PP +S S SP
Sbjct: 146 TGPQNYSPQYDSYDVKSGVAVGGLAGYPGP-AGPPGPP--GPPGTSGHPGSPGSPGYQGP 202
Query: 960 SGTPGTSSDSRQRSPLSDYMNLDFSSP-----KSPKPGAPSGHPVGSLDGLLSPEASSPY 1014
G PG + S P + S P +S +PG P + G+ P +
Sbjct: 203 PGEPGQAGPSGPPGPPG---AIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259
Query: 1015 P-----------------------------------PLPPRPSASPSSSLQP-------- 1031
P P P P +P +P
Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319
Query: 1032 -----------PPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVA 1080
P PP P P + GP + + G G+ A
Sbjct: 320 RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGA 379
Query: 1081 ATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDP--HRGAKVIR- 1137
PP P P P + G + A PP P GA +R
Sbjct: 380 QGPPGPPGINGSPGGKGEMGPAG----------IPGAPGLMGARGPPGPAGANGAPGLRG 429
Query: 1138 ---------ADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEG 1188
A + G R E +P + + + + + G
Sbjct: 430 GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPG 489
Query: 1189 GVG-VGPGG--GDEPPTSPRQLQ-PAPPLAPQGRPWTPGQPG--GLVGCPGSGGSPMRRE 1242
G GP G G++ P R PA P G P G PG G+ G PGS G P
Sbjct: 490 FRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP---- 545
Query: 1243 TSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGST 1302
S G R P P P+ P + PG K + G A G
Sbjct: 546 GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG----------APGKNGE 595
Query: 1303 GGGCGGPGPGALPPAN 1318
GG GGPGP P N
Sbjct: 596 RGGPGGPGPQGPPGKN 611
Score = 57.0 bits (136), Expect = 1e-07
Identities = 163/736 (22%), Positives = 214/736 (29%), Gaps = 112/736 (15%)
Query: 651 DGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGP 710
D +P PG+ + G C S P P + S ++ A GPAGP
Sbjct: 122 DPGIPGQPGSPGSPGPPGICES---CPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP 178
Query: 711 ----APTSAAGRTFPASGGGYKA--SSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNG 764
P +G GY+ P ++ P G + P+G
Sbjct: 179 PGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGP-------------PGPPGAIGPSG 225
Query: 765 ----DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDS 820
D + P G P PG + G+PG R + G++
Sbjct: 226 PAGKDGESGRPGRPGERGLPGP-------PGIKGPAGIPGFPGMKGHRGFDGRNGEKGET 278
Query: 821 DQYVLMSS-----------PVG-RILEEERLEPQATPGPSQAASAFGA-------GPTQP 861
L P+G R ER P PG + A GA GP P
Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRP-GLPGAAGARGNDGARGSDGQPGPPGP 337
Query: 862 P-------HPVVPSPVRPSGGR-PEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEP 913
P P V P+G G GQRG +G P P ++
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING------- 390
Query: 914 KSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRS 973
SPG GE G P AP L+ + + +P G+G PG + +
Sbjct: 391 -SPGGK-----GEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG 444
Query: 974 PLSD-----YMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPS-- 1026
P + + + + K G+P L G E +P P P+ P
Sbjct: 445 PRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG-ERGAPGFRGPAGPNGIPGEK 503
Query: 1027 --SSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPP 1084
+ + P P P P V GPG S G D G
Sbjct: 504 GPAGERGAPGPAGPRGAAGEPGRDGVPG--GPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561
Query: 1085 QPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRG-AKVIRADPQG- 1142
+P PP P R G + G P P K PQG
Sbjct: 562 RP--GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGP 619
Query: 1143 ----GRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGD 1198
G +T P P + + G G G
Sbjct: 620 PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA 679
Query: 1199 EPPTSPRQLQPAP-------PLAPQGRPWTPGQPG--GLVGCPGSGGSPMRR-------- 1241
P L AP P P+G G PG G G PG G P R
Sbjct: 680 PGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739
Query: 1242 ETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGS 1301
+ G G + ++ P P P PP P QPGDK G L G+ G
Sbjct: 740 KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE-GGAPGLPGIAGPRGSPG 798
Query: 1302 TGGGCGGPGPGALPPA 1317
G G PGP P A
Sbjct: 799 ERGETGPPGPAGFPGA 814
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 73.2 bits (178), Expect = 2e-12
Identities = 150/601 (24%), Positives = 192/601 (31%), Gaps = 160/601 (26%)
Query: 858 PTQPPHPVVPSPVRPSGG----------RPEGFLGQRGRAVRPTRLSL------EGLPSL 901
P PP P P P P G +P + G A P R E SL
Sbjct: 250 PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSL 309
Query: 902 PSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPA-----------PP---LLASAASSSS 947
P + YP P P + + PG PP PP L S S
Sbjct: 310 PHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSR 369
Query: 948 LLSASSPASSLGS---------GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHP 998
+ S+ SPA++ G PGT++ S S S L P PGA
Sbjct: 370 MDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSS--SSNTGLRGVEPNPGIPGADHYQT 427
Query: 999 VG---SLDGLLSPEASSPYPPLPPRPSASPSSSLQP----PPPPPAPGELYRLPPASAVA 1051
S G L P A S P P+A+P SL P PPPPP P L R PP A
Sbjct: 428 PALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCP-RLLRPPPPPA-- 484
Query: 1052 TAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPE--------AARVA---- 1099
+GP ++ ++G+ E F PP+P A PP P A+R +
Sbjct: 485 WLKGPACRAAR-----EDGEILEELFFGTEGPPRP-APPPLPHREGFLGPPASRFSVGTQ 538
Query: 1100 ----SPTSGVKRLSLMEQVSGVEAFLQA---SQPPDPH--RGAKVIRADPQGGRRRHSSE 1150
PT S SG + A S PP P+ R + P +
Sbjct: 539 DSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPP 598
Query: 1151 TFSSTTTVTPVSPSFAHNPK----RHNSASVENVSLRKSSEGGVG------------VGP 1194
T + P PS H R + VS K+ E G G V P
Sbjct: 599 LVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPP 658
Query: 1195 GGGDEPPTSPRQLQPAPPLAPQGRPWTPGQ----PGGLVGC------------------P 1232
G G+ P PR L PP + + P + P GL
Sbjct: 659 GVGELPARGPR-LFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEA 717
Query: 1233 GSGGSPMRRETSAGFQNGLNY----------IAI----------------DVREEPGLPP 1266
G P +E A Q+ +A+ + + P LPP
Sbjct: 718 GVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPP 777
Query: 1267 -----------QPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCG-GPGPGAL 1314
QPQPPPPP P P +SL ++ G G PG L
Sbjct: 778 PPPLAKFPPPSQPQPPPPPPPSPA-----SLLKSLASVLEGQKYCYRGTGAAVSTRPGPL 832
Query: 1315 P 1315
P
Sbjct: 833 P 833
Score = 65.5 bits (158), Expect = 3e-10
Identities = 204/978 (20%), Positives = 312/978 (31%), Gaps = 211/978 (21%)
Query: 376 AAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPV 435
A G PV A P PV P+ + LSG G G L P G + R +
Sbjct: 190 AKRGGPPVKRAAEP----PVVQPVPPA-ALSGPSGEEG----LSPGG---KRRRGCNSEQ 237
Query: 436 AHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDP 495
PP P PPPP P PP P PL PG + S + P
Sbjct: 238 TGLPPGLPLPPP----------PLPPPPPPPPPPPPPL---PGL-----ATSPPFQLTKP 279
Query: 496 GFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRS 555
G S +G + G PE PP R + Y +
Sbjct: 280 GLWST-LHGDAWG------------PERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPG 326
Query: 556 YRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPS 615
+R V R ++ P +P + L E + R+ S
Sbjct: 327 HRLVPAAPPGPGPRPPGAESHGCL------PATRPPGSDLRESRVQRSRMDSSVS----- 375
Query: 616 CPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSG---SGSCRS 672
PA++ A PY G+ SSSS+ ++ G + P + G+ + +
Sbjct: 376 -PAAT--TACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEV 432
Query: 673 DDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSP 732
+ + P++ S+ K L AA + P GP+ P P P +
Sbjct: 433 SHHGRLGPSAHSSRKPFLGAPAATPHLSLPP--GPSSPPPPPCPRLLRPPPPPAWLKGPA 490
Query: 733 AESSPEDSGYMR-MWCGSK-------LSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFF 784
++ ED + ++ G++ + H +G L P +V D+ T TPP
Sbjct: 491 CRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPT 550
Query: 785 SAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLE---- 840
+++ + P P S+ P D SP + +
Sbjct: 551 TSSSNSNSGSHSSSPAG-----PVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLA 605
Query: 841 -PQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLP 899
P A P ++ + P P V P P G P G +A +P + LP
Sbjct: 606 LPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVG-PGPPPGPLSKAPQPVPPGVGELP 664
Query: 900 SL-PSMHEYPLPP---EPKSPGEYINIDFG---------------------EPGARLSPP 934
+ P + ++P P + + P E+ + G E G PP
Sbjct: 665 ARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
Query: 935 APPLLASAAS---SSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKP 991
AS S + + + ++PA ++ + T T++ + + K P P
Sbjct: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQE-----------EEKKPPP 773
Query: 992 GAPSGHPVGSLDGLLSPEASSPYPPLPP-----------------------------RPS 1022
P P+ P P PP PP RP
Sbjct: 774 ALPPPPPLAKFP---PPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPG 830
Query: 1023 ASPSSSLQPPPPPPAPGELYRLPPASAVATAQG---PGAASSLSSDTGDNGDYTEMAFG- 1078
P++ P PP A LPP SA +AQG P A+SS T E G
Sbjct: 831 PLPTTQYSPGPPSGATA----LPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE 886
Query: 1079 -------VAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQV----------------- 1114
PP P++ PP + V S +L+E+V
Sbjct: 887 EPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACE-TLVERVGRSATDPADPVDTAEPA 945
Query: 1115 -SGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSE------TFSSTTTVTP---VSPS 1164
SG E L +Q + G + + ++ H E + P + +
Sbjct: 946 DSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKA 1005
Query: 1165 FAHNPKRHNSASVENVSLRKSSEGG-----VGVGPGGGDEPPTSPR-------QLQPAPP 1212
A PK + + N+ L+ G +G +PPT+P QP PP
Sbjct: 1006 KAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPP 1065
Query: 1213 LA----PQGRPWTPGQPG 1226
A + R PG PG
Sbjct: 1066 SASVPGKKAREEAPGPPG 1083
Score = 65.1 bits (157), Expect = 4e-10
Identities = 134/505 (26%), Positives = 169/505 (33%), Gaps = 117/505 (23%)
Query: 854 FGAGPTQPP-----HPVVPSPVRP---SGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMH 905
+GA PP P V PV P SG E L G+ R GLP +
Sbjct: 188 YGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLP 247
Query: 906 EYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSL-----GS 960
PLPP P P PP PPL A S L+ S+L G
Sbjct: 248 PPPLPPPPPPP---------------PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGP 292
Query: 961 GTPGTSSDSRQRS----------PLSDYM------NLDFSSPKSP---KPGA------PS 995
G++ RQ P Y L ++P P PGA P+
Sbjct: 293 ERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPA 352
Query: 996 GHPVGS-----------LDGLLSPEASS---PYPP-----LPPRPSASPSSSLQ------ 1030
P GS +D +SP A++ PY P LP ++S SSS
Sbjct: 353 TRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRG 412
Query: 1031 PPPPPPAPGELYRLPPASAVA--TAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIA 1088
P P PG + PA V+ GP A SS G ++ + P P
Sbjct: 413 VEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPP 472
Query: 1089 AP----PKPEAARVASPTSGVKRLS---LMEQVSGVEAFLQASQPPDPHRGAKVIRADPQ 1141
P P P A + P R L E G E + + PP PHR + P
Sbjct: 473 CPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHR--EGFLGPPA 530
Query: 1142 GGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPP 1201
R S T S T TP +P+ S+S N SS GP PP
Sbjct: 531 S---RFSVGTQDSHTPPTPPTPT--------TSSSNSNSGSHSSSP----AGPVSFPPPP 575
Query: 1202 TSPRQLQPAP-PLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVRE 1260
R + P P P +P P P + P + S + TS F+ R
Sbjct: 576 YLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRR-----PESPRP 630
Query: 1261 EPGLPPQPQ----PPPPPL---PQP 1278
P P+ PPP PL PQP
Sbjct: 631 RVSFPKTPEVGPGPPPGPLSKAPQP 655
Score = 47.0 bits (110), Expect = 1e-04
Identities = 93/375 (24%), Positives = 128/375 (34%), Gaps = 95/375 (25%)
Query: 984 SSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYR 1043
S + PG S L P P PPLPP PPPPPP P
Sbjct: 218 SGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPP-----------PPPPPPPPP---- 262
Query: 1044 LPPASAVATA-----QGPGAASSLSSDT-------GDNGDYTEMAFGVAATPPQPIAA-- 1089
PP +AT+ PG S+L D + E + P P A
Sbjct: 263 -PPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYT 321
Query: 1090 --PPKPEAARVASPTSGVKRLSLMEQVSGVEAF--LQASQPPDPH-RGAKVIRADPQGGR 1144
PP A P G + G E+ L A++PP R ++V R+
Sbjct: 322 AHPPGHRLVPAAPPGPG-------PRPPGAESHGCLPATRPPGSDLRESRVQRS------ 368
Query: 1145 RRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSP 1204
R SS + ++TT P +PS P + + S S+ G GV P G P +
Sbjct: 369 RMDSSVSPAATTACVPYAPS---RPPGLPGTTTSSSSSSSSNTGLRGVEPNPG--IPGAD 423
Query: 1205 RQLQPAPPLAPQGR--PWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEP 1262
PA ++ GR P +G P +
Sbjct: 424 HYQTPALEVSHHGRLGPSAHSSRKPFLGAPAA------------------------TPHL 459
Query: 1263 GLPPQP-QPPPPPLP---QPGDKSSWGR------TRSLGGLISAVGVGSTGGGCGGPGP- 1311
LPP P PPPPP P +P +W + R G ++ + G+ G P P
Sbjct: 460 SLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPL 519
Query: 1312 ----GAL-PPANTYA 1321
G L PPA+ ++
Sbjct: 520 PHREGFLGPPASRFS 534
Score = 45.1 bits (105), Expect = 5e-04
Identities = 208/901 (23%), Positives = 276/901 (30%), Gaps = 232/901 (25%)
Query: 385 VAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSR--------------- 429
V +P PGP R P + SH G A P G L+ SR
Sbjct: 330 VPAAPPGPGP-RPPGAESH---------GCLPATRPPGSDLRESRVQRSRMDSSVSPAAT 379
Query: 430 SMSMPVAHSPP----AATSPGSLSSSSGHGSGSYPPPPGP------HPPLPHPLHHGP-G 478
+ +P A S P T+ S SSSS G P PG P HHG G
Sbjct: 380 TACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLG 439
Query: 479 QRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGE 538
S G+P+ +SL SSP R P + + P R GE
Sbjct: 440 PSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGE 499
Query: 539 -----FYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSA 593
F+G RP G A G + +++ TP P P SS+
Sbjct: 500 ILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQD-SHTPPTP----PTPTTSSS 554
Query: 594 SLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGY 653
+ + SGS P+ P S P P P I+ S + D
Sbjct: 555 NSN---------SGSHSS-SPAGPVSFP-----PPPYLARSIDPLPRPPSPAQNPQDPPL 599
Query: 654 MPMT------PGAALAGSGSGSCRSDDYMPMSPAS-VSAPKQILQPRAAAAAAAAVPSAG 706
+P+T P ++ + SGS R P SP VS PK P G
Sbjct: 600 VPLTLALPPAPPSSCHQNTSGSFRR----PESPRPRVSFPK--------------TPEVG 641
Query: 707 PAGP-APTSAAGRTFPASGGGYKASSPA----ESSPEDSGYMRMWCGSKLSMEHADGKLL 761
P P P S A + P G A P +P + + E A+ K+L
Sbjct: 642 PGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFE----------EPAEFKIL 691
Query: 762 PNGDYLNVSP--SDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGD 819
P+G N+ +++ A + P PL+ S P T
Sbjct: 692 PDG-LANIMKMLDESIRKEEEQQQHEAGVAPQ-PPLKEPFASLQSPFPTDTAPTTTAPAV 749
Query: 820 S-DQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPE 878
+ ++ EEE+ P A P P A QPP P PSP
Sbjct: 750 AVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLAS 809
Query: 879 GFLGQR------GRAVR------PTRLSLEGLPS----LPSMHEYPLP---PEPKSPGEY 919
GQ+ G AV PT G PS LP P P+P +
Sbjct: 810 VLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSS 869
Query: 920 INIDFGEPGAR---------------LSPPAPPLLASAASSSSLL--------------- 949
G P AR PP P L A S S +L
Sbjct: 870 QFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVG 929
Query: 950 -SASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDF------------------------- 983
SA+ PA + + P S R P
Sbjct: 930 RSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRA 989
Query: 984 -------------SSPKSPKPGAPSGHPVGSLDGLLSPE-------------ASSPYPPL 1017
+ K+ P S +G+LD L S E AS PP
Sbjct: 990 CKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLD-LQSEEIQGREKSRPDLGGASKAKPPT 1048
Query: 1018 PPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAF 1077
P P ++P+ S QP PP + +P A A GP S D ++
Sbjct: 1049 APAPPSAPAPSAQPTPPSAS------VPGKKAREEAPGPPGVS-----RADMLKLRSLSE 1097
Query: 1078 GVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIR 1137
G PPK R+ SG K + +V E L+ + H A V+R
Sbjct: 1098 G-----------PPKELKIRLIKVESGDKETFIASEVE--ERRLRMADLTISHCAADVVR 1144
Query: 1138 A 1138
A
Sbjct: 1145 A 1145
Score = 40.4 bits (93), Expect = 0.011
Identities = 82/337 (24%), Positives = 113/337 (33%), Gaps = 55/337 (16%)
Query: 991 PGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSA----SPSSSLQPPPPPPAPGELYRLPP 1046
PGA + +L GL A S PP PP SA S+ PP PAP LPP
Sbjct: 8 PGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAP-----LPP 62
Query: 1047 ASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVK 1106
S +G ++ + A P+P+ + V +
Sbjct: 63 -----------------SHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPA 105
Query: 1107 RLSLMEQVSGVEAFLQASQPPDP------HRGAKVIRADPQGGRRRHSSETFSSTTTVTP 1160
+ L EQ+ + S+ G P+ GR + + T +
Sbjct: 106 QPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQH 165
Query: 1161 VSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPW 1220
+ + N +E+ + GG V EPP +QP PP A G
Sbjct: 166 RAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAA--EPPV----VQPVPPAALSGPSG 219
Query: 1221 TPG-QPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPG 1279
G PGG RR Q GL + + P PP P PPPPP P PG
Sbjct: 220 EEGLSPGG-----------KRRRGCNSEQTGLPP-GLPLPPPPLPPPPPPPPPPPPPLPG 267
Query: 1280 DKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPP 1316
+S + GL S + G G G+ PP
Sbjct: 268 LATSPPFQLTKPGLWSTL----HGDAWGPERKGSAPP 300
Score = 34.3 bits (77), Expect = 0.82
Identities = 41/161 (25%), Positives = 51/161 (31%), Gaps = 26/161 (16%)
Query: 1158 VTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQG 1217
V PV P+ P S R + G+ PG PP P P PP P
Sbjct: 206 VQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPP- 264
Query: 1218 RPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQ 1277
PG SP + T G + L+ A + PP+ Q LP
Sbjct: 265 -------------LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPH 311
Query: 1278 PGDKSSWGRTRSLGG--LISAVGVGSTGGGCGGPGPGALPP 1316
P + T G L+ A PGPG PP
Sbjct: 312 PYPYPAPAYTAHPPGHRLVPA----------APPGPGPRPP 342
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 72.0 bits (175), Expect = 4e-12
Identities = 175/666 (26%), Positives = 210/666 (31%), Gaps = 107/666 (16%)
Query: 692 PRAAAAAAAAVPSAGPAG-PAPTSAAGRTFPA--SGGGYKASSPAESSPEDSGYM--RMW 746
P+ A + GP G P P G+ FP G G K S + G R
Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGL 1932
Query: 747 CGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSL 806
G S+ + D +LL + + V T D S + P E RG G
Sbjct: 1933 RGEPGSVPNVD-RLLETAGIKASALREIVETW---DESSGSFLPVPERRRGPKGDSGEQG 1988
Query: 807 PRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVV 866
P + P G+ P + L + PGPS A P +P P +
Sbjct: 1989 PPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGE----PGKPGIPGL 2044
Query: 867 PSPVRPSG--GRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDF 924
P G GRP G G+RG +G P LP P PP P PG +++D
Sbjct: 2045 PGRAGGVGEAGRP-GERGERGEKGERGEQGRDGPPGLPGT---PGPPGP--PGPKVSVD- 2097
Query: 925 GEPGARLS-PPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDF 983
EPG LS PP L A P G PG D + P N
Sbjct: 2098 -EPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGD--RGVPGIKGDRGEPGPRGQDGNPGL 2154
Query: 984 ---------------SSPKSPKPGAPSGH----PVGSLDGLLSPEASSPYPPLPPRPSAS 1024
P+ P PG GH P G+ GL P L P +
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGP-PGPVGGHGDPGPPGA-PGLAGPAGPQGPSGLKGEPGET 2212
Query: 1025 --PSSSLQPP------PPPPAPGELYR------LPPASAVATAQGPGAASSLSSDTGDNG 1070
P L P P PP P L LP G S GD G
Sbjct: 2213 GPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRG 2272
Query: 1071 DYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPH 1130
GV +P P PK E +P V L + G L +P
Sbjct: 2273 SP-----GVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEP- 2326
Query: 1131 RGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGV 1190
GAK R P G R E A P + K +G
Sbjct: 2327 -GAKGDRGLP--GPRGEKGEA------------GRAGEPGDPGEDGQKGAPGPKGFKGDP 2371
Query: 1191 GVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNG 1250
GVG G PP P G P PG P G+VG PG G R E +G
Sbjct: 2372 GVGVPGSPGPPGPPGVK------GDLGLPGLPGAP-GVVGFPGQTGP--RGEMGQPGPSG 2422
Query: 1251 LNYIAIDVREEPGL--PPQPQPPPPPLPQPGDKSSWGRTRSLG--GLISAVGVGSTG--G 1304
E GL PP + P PL PG S G + G G GVG G G
Sbjct: 2423 ----------ERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG 2472
Query: 1305 GCGGPG 1310
G PG
Sbjct: 2473 ERGEPG 2478
Score = 58.9 bits (141), Expect = 3e-08
Identities = 235/1005 (23%), Positives = 296/1005 (29%), Gaps = 200/1005 (19%)
Query: 362 RTASEGDGGAAAGAAAAGARPVSVA-GSPLSPGPVRAP-------LSRSHTLSGGCGGRG 413
RT + G G A A G R A G P SPG P L S L G G G
Sbjct: 1279 RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPG 1338
Query: 414 SKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHG----SGSYPP--PPGPHP 467
+ P G P A PG + G G G P PPGP
Sbjct: 1339 ERGPRGPKG----------------EPGA--PGQVIGGEGPGLPGRKGDPGPSGPPGPRG 1380
Query: 468 PLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAET 527
PL P GP P + G + G E G +PG+ S P+
Sbjct: 1381 PLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGP 1440
Query: 528 PPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPV 587
P + G E +P S + R G DRG
Sbjct: 1441 PGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGF---------------- 1484
Query: 588 PQPSSASLDEYTLMRATFSGSAGRLCPSCPASS---PKVAYHPYPEDYGDIEIGSHRSSS 644
P P +G G P PA S P VA P + + R
Sbjct: 1485 PGPLGE------------AGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGE 1532
Query: 645 SNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPS 704
G P G A+AG D P P + + P P
Sbjct: 1533 KGEPGRPG-DPAVVGPAVAGPKG---EKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPK 1588
Query: 705 AGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNG 764
P P GR P G P G + DG++ G
Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG--------PVGPRGRDGEVGEKG 1640
Query: 765 DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
D P D G G LRG PG + P GD
Sbjct: 1641 D--EGPPGDPGLPG----------KAGERGLRGAPG---------VRGPVGEKGDQ---- 1675
Query: 825 LMSSPVGRILEEERLEPQATPGPSQAASAFG-AGPTQPPHPVVPSPVRPSGGRPEGFLGQ 883
G E+ R +PG S G GP PP +V + G R +G G
Sbjct: 1676 ------GDPGEDGR---NGSPGSSGPKGDRGEPGPPGPPGRLVDT---GPGAREKGEPGD 1723
Query: 884 RGRAVRPTRLSLEGLPSLP---SMHEYPLPPEPK-SPGEYINIDFGEPGARLSPPAPPLL 939
RG+ GLP P + + PP P+ PG + GE G R PP L
Sbjct: 1724 RGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG--VRGPAGEKGDR----GPPGL 1777
Query: 940 ASAASSSSLLSASSPASSLGS----------GTPGTSSDSRQRSPLSDYMNLDFSSPKSP 989
+ A+ P+ G+ G PG + P S L +
Sbjct: 1778 DGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGP-SGPPGLPGKPGEDG 1836
Query: 990 KPG--APSGHPVG-SLDGLLSPE----ASSPYPPLPPRPSASPSSSLQPPPPPPAPGELY 1042
KPG +G P DG + AS P+ L P PP PG +
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896
Query: 1043 RLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPT 1102
PP G +TG G+ + G +P + P T
Sbjct: 1897 --PPGQGFPGVPGGTGPKGDRGETGSKGE--QGLPGERGLRGEPGSVPNVDRLLE----T 1948
Query: 1103 SGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVS 1162
+G+K +L E V + S P P R R P+G
Sbjct: 1949 AGIKASALREIVETWDE-SSGSFLPVPER-----RRGPKGDSGEQGP------------- 1989
Query: 1163 PSFAHNPKRHNSASVENVSLRKSSEGGVG-VGPGG---GDEPPTSPRQLQPAPPLAPQGR 1218
P + K G G GP G G+ P P L P G+
Sbjct: 1990 ------PGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEP-----GK 2038
Query: 1219 PWTPGQPG-----GLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPP 1273
P PG PG G G PG G R E + G + PGLP P PP P
Sbjct: 2039 PGIPGLPGRAGGVGEAGRPGERGE--RGEKGERGEQGRD-------GPPGLPGTPGPPGP 2089
Query: 1274 PLPQPG-DKSSWGRTRSLG--GLISAVGVGSTGGGCGGPGPGALP 1315
P P+ D+ G + G GL A G + G G G +P
Sbjct: 2090 PGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134
Score = 55.5 bits (132), Expect = 3e-07
Identities = 135/530 (25%), Positives = 162/530 (30%), Gaps = 115/530 (21%)
Query: 858 PTQPPHPVVPSPVRPSGGRP----EGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEP 913
P P P P P G GF G GR P R G P P + P P P
Sbjct: 1274 PGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGP 1333
Query: 914 K-SPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQR 972
+ PGE G G + P AP ++ P G PG S R
Sbjct: 1334 RGDPGER-----GPRGPKGEPGAP---------GQVIGGEGPGLPGRKGDPGPSGPPGPR 1379
Query: 973 SPLSDYMNLDFSSPKSPKPGAPSGHPVGSLD-----GLLSPEASSPYPPLPPRPSASPSS 1027
PL D P+ P PG P G G P P P P S
Sbjct: 1380 GPLGD------PGPRGP-PGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSP 1432
Query: 1028 SLQPPPPPP------------APGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEM 1075
Q P PP APG L P + +GP A D G G E
Sbjct: 1433 GPQGPVGPPGKKGEKGDSEDGAPG-LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491
Query: 1076 AFGVAATPPQPIAAPPKPEAA--RVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPH--- 1130
PP P + P A A G + + G + +P DP
Sbjct: 1492 GEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKG-----EPGRPGDPAVVG 1546
Query: 1131 ---RGAKVIRAD--PQGGRRRHSSE-TFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRK 1184
G K + D P G R + V P P +P
Sbjct: 1547 PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDP--------------- 1591
Query: 1185 SSEGGVGV----GPGGGDEPP---TSPRQLQPAPPLAPQGR------------PWTPGQP 1225
G +G+ GP G PP P + P P+ P+GR P PG P
Sbjct: 1592 GDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLP 1651
Query: 1226 G-----GLVGCPGSGGSPMRRETSAG--FQNGLNYIAIDV-----REEPGLPPQP----- 1268
G GL G PG G P+ + G ++G N R EPG P P
Sbjct: 1652 GKAGERGLRGAPGVRG-PVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD 1710
Query: 1269 -QPPPPPLPQPGDKSSWGRTRSLG--GLISAVGVGSTGGGCGGPGPGALP 1315
P +PGD+ G G GL A G G G PGP P
Sbjct: 1711 TGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDP 1760
Score = 53.5 bits (127), Expect = 1e-06
Identities = 131/499 (26%), Positives = 165/499 (33%), Gaps = 101/499 (20%)
Query: 846 GPSQAASAFGA-GPTQPPHPVVPSPVRPSG----GRPEGFLGQRGRAVRPTRLSLEGLPS 900
GP A G GP PP +P PV P G G P G G +G +GLP
Sbjct: 1872 GPKGERGAPGILGPQGPPG--LPGPVGPPGQGFPGVPGG-TGPKGDRGETGSKGEQGLPG 1928
Query: 901 LPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLS--ASSPASSL 958
+ GEPG+ P LL +A +S L + S
Sbjct: 1929 ERGLR-------------------GEPGS--VPNVDRLLETAGIKASALREIVETWDESS 1967
Query: 959 GSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPG--APSGHPVGSLDGLLSPEASSPYPP 1016
GS P R+R P D S + PG P G P + L + P P
Sbjct: 1968 GSFLP---VPERRRGPKGD-------SGEQGPPGKEGPIGFPG---ERGLKGDRGDPGPQ 2014
Query: 1017 LPP------RPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNG 1070
PP R PS P P PG R A V A PG + G+ G
Sbjct: 2015 GPPGLALGERGPPGPSGLAGEPGKPGIPGLPGR---AGGVGEAGRPGERG----ERGEKG 2067
Query: 1071 DYTEMAF----GVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGV--EAFLQAS 1124
+ E G+ TP P PP P+ + V P G+ + G E
Sbjct: 2068 ERGEQGRDGPPGLPGTPGPP--GPPGPKVS-VDEPGPGLSGEQGPPGLKGAKGEPGSNGD 2124
Query: 1125 QPPDPHRGAKVIRADP-QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLR 1183
Q P RG I+ D + G R +P P A E
Sbjct: 2125 QGPKGDRGVPGIKGDRGEPGPRGQDG------------NPGL---PGERGMAGPEGKPGL 2169
Query: 1184 KSSEGGVGVGPGGGDE-PPTSPRQLQPAPPLAPQGRPWTPGQPG----GLVGCPGSGGSP 1238
+ G G G GD PP +P PA P P G PG+ G GL G G+ G P
Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP 2229
Query: 1239 MRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLG--GLISA 1296
S + + PGLP Q P PG + G+ G G+ +
Sbjct: 2230 GPPGPSG---------LVGPQGSPGLPGQVGETGKP-GAPGRDGASGKDGDRGSPGVPGS 2279
Query: 1297 VGVGSTGGGCGGPGPGALP 1315
G+ G G PGP P
Sbjct: 2280 PGLPGPVGPKGEPGPTGAP 2298
Score = 40.0 bits (92), Expect = 0.015
Identities = 73/289 (25%), Positives = 92/289 (31%), Gaps = 45/289 (15%)
Query: 1056 PGAASSLSSDTGDNGDYTEMAFGVAATP--PQPIAAPPKPEAARVASPTSGVKRLSLMEQ 1113
PG S + D+G + A AT P+PE V P M
Sbjct: 1205 PGMDSVQTFFAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEM-- 1262
Query: 1114 VSGVEAFLQASQPPDPHRGAKVIRADPQG--GRRRHSSETFSSTTTVTPVSPSFAHNPKR 1171
G+ Q P DP + PQG G E P SP A NP
Sbjct: 1263 --GLRG--QVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT 1318
Query: 1172 HNSASVENVSLRKSSEGGVGV-GPGGGDEPPTSPRQL---------------QPAPPLAP 1215
+ ++ G G GP G P +P Q+ P+ P P
Sbjct: 1319 PGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGP 1378
Query: 1216 QGRPWTPGQPGGLVGCPGSG-----GSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQP 1270
+G PG P G G PG+ G R + G+ EPGLP P
Sbjct: 1379 RGPLGDPG-PRGPPGLPGTAMKGDKGDRGERGPPGPGEGGI------APGEPGLPGLPGS 1431
Query: 1271 PPP--PLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPA 1317
P P P+ PG K G + A G+ G G GP P A
Sbjct: 1432 PGPQGPVGPPGKKGEKGDSED-----GAPGLPGQPGSPGEQGPRGPPGA 1475
Score = 38.1 bits (87), Expect = 0.057
Identities = 96/422 (22%), Positives = 126/422 (29%), Gaps = 99/422 (23%)
Query: 845 PGPSQAASAFGA-------GPTQPPHPVVPSPVRPSG--------GRPE-GFLGQRGRAV 888
PGPS G GP PP P P V P G G P G G RG
Sbjct: 2418 PGPSGERGLAGPPGREGIPGPLGPPGP--PGSVGPPGASGLKGDKGDPGVGLPGPRGERG 2475
Query: 889 RPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSL 948
P +G P PP + GE G + + L S+ +
Sbjct: 2476 EPGIRGEDGRPGQEGPRGLTGPPGSR----------GERGEKGDVGSAGLKGDKGDSAVI 2525
Query: 949 LSASSPASSLGS-GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLS 1007
L P + G G G + P D + K +PG + L GLL
Sbjct: 2526 LGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKG-EPGDKGSAGLPGLRGLLG 2584
Query: 1008 PEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTG 1067
P+ +P P + + P G++ + P + +G A L + G
Sbjct: 2585 PQGQPGAAGIPGDPGSPGKDGV--PGIRGEKGDVGFMGPRG-LKGERGVKGACGLDGEKG 2641
Query: 1068 DNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPP 1127
D G+ A P +P A K E P G E + P
Sbjct: 2642 DKGE--------AGPPGRPGLAGHKGEMGEPGVPGQS--------GAPGKEGLIG----P 2681
Query: 1128 DPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSE 1187
RG D Q G + E K
Sbjct: 2682 KGDRGF-----DGQPGPKGDQGE---------------------------------KGER 2703
Query: 1188 GGVGVG----PGGGDE---PPTSPRQLQPAPPLAPQGRPWTPGQPG-GLVGCPGSGGSPM 1239
G G+G P G D PP P + P P QG+ G PG +VG PG G+P
Sbjct: 2704 GTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPG 2763
Query: 1240 RR 1241
R
Sbjct: 2764 ER 2765
Score = 34.7 bits (78), Expect = 0.63
Identities = 48/179 (26%), Positives = 58/179 (32%), Gaps = 34/179 (18%)
Query: 365 SEGDGGAAAGAAAAGARPV-SVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGG 423
++G+ G+ G R V + G PGP G G G + P G
Sbjct: 2115 AKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP--------RGQDGNPGLPGERGMAGPEGK 2166
Query: 424 -ALQHSRSMSMPVA-HSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRP 481
LQ R PV H P L+ +G P GP P GP R
Sbjct: 2167 PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG--------PQGPSGLKGEPGETGPPGRG 2218
Query: 482 SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAET----PPARDGGGG 536
+G A G P PG L SPG P + ET P RDG G
Sbjct: 2219 LTGPTGAVGLPGPPGPSGLVGPQGSPG-----------LPGQVGETGKPGAPGRDGASG 2266
Score = 33.9 bits (76), Expect = 1.1
Identities = 34/133 (25%), Positives = 42/133 (31%), Gaps = 13/133 (9%)
Query: 367 GDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAG--GA 424
G G GA +V G P + G AP + L G G +G + P G G
Sbjct: 2284 GPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGE 2343
Query: 425 LQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSG 484
+ P A P G G P PPGP PG + G
Sbjct: 2344 AGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP-----------PGVKGDLG 2392
Query: 485 SASASGSPSDPGF 497
G+P GF
Sbjct: 2393 LPGLPGAPGVVGF 2405
Score = 31.6 bits (70), Expect = 5.3
Identities = 39/133 (29%), Positives = 42/133 (31%), Gaps = 3/133 (2%)
Query: 366 EGDGGAAAGAAAAGARPVSVAGSPLSPGP--VRAPLSRSHTLSGGCGGRGSKVALLPAGG 423
+G GA G V V GSP PGP V+ L L G G G P G
Sbjct: 2356 DGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLP-GLPGAPGVVGFPGQTGPRGE 2414
Query: 424 ALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSS 483
Q S +A P PG L GS P G P PG R
Sbjct: 2415 MGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGER 2474
Query: 484 GSASASGSPSDPG 496
G G PG
Sbjct: 2475 GEPGIRGEDGRPG 2487
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 71.2 bits (173), Expect = 6e-12
Identities = 87/353 (24%), Positives = 122/353 (34%), Gaps = 42/353 (11%)
Query: 791 GGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQA 850
GG P G+ G + +P+ + P GR + P + PG
Sbjct: 95 GGPP--GLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 851 AS-AFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPL 909
S +GP +P +P P G +P+ P + P S H
Sbjct: 153 PSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI---------PPPVPSTPRPIQSSPHNRGS 203
Query: 910 PPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDS 969
PP P P + PG PP P +A S+ SP SS SS
Sbjct: 204 PPVPGGPRQ------PSPGPT-PPPFPGNRGTALGGGSI--RQSPLSS--------SSPF 246
Query: 970 RQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSL 1029
R PL + P P P + + P + PP+P P S SS
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 1030 QPPPPPPAPGELYRLPPASA--VATAQGPGAASSLSSDT---GDNGDYTEMAFGVAATPP 1084
PPPPPP+ LPP+S+ T + P SLSS T G + + PP
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPP 366
Query: 1085 QPI--------AAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDP 1129
P+ PP P +R S + + + SGV++ +PP P
Sbjct: 367 PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLP 419
Score = 53.5 bits (127), Expect = 1e-06
Identities = 81/303 (26%), Positives = 108/303 (35%), Gaps = 57/303 (18%)
Query: 843 ATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRA-----VRPTRLSLEG 897
+TP P Q++ P P P PSP G P F G RG A +R + LS
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSP----GPTPPPFPGNRGTALGGGSIRQSPLSSSS 244
Query: 898 -------LPSLPS--MHEYPLPPEP---KSPGEYINIDFGEPGARLSPPAPPLLASAASS 945
LP PS + + P PP P P + P PP P +ASS
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS 304
Query: 946 SSLLSASSPASSLGSGTPGTSS--DSRQRSPLSDYMNLDFSSPKSPKPGA-------PSG 996
+ P+ P +SS D R P + ++L S+P P PG PS
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN-LSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 997 HPVGSLDGLLSPEASSPYPPLPP----------------RPSAS----PSSSLQPPPPPP 1036
P + P S P PP PP PS S P S +PP PP
Sbjct: 364 RPPPPVRD--PPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPD 421
Query: 1037 APGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAA 1096
P PP +T+ G S D ++ Y + PP+P K +
Sbjct: 422 RPSA--GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDL--PPPEPYVQTTKSYPS 477
Query: 1097 RVA 1099
++A
Sbjct: 478 KLA 480
Score = 43.5 bits (101), Expect = 0.001
Identities = 82/380 (21%), Positives = 116/380 (30%), Gaps = 78/380 (20%)
Query: 959 GSGTPGTSSDSRQRSP-LSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYP-P 1016
G G PG + P L N D S S P P G S P +P P
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153
Query: 1017 LPPRPSA--SPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTE 1074
P S P + PPP P + +PP P + S + G
Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPV-------PSTPRPIQSSPHNRG---- 202
Query: 1075 MAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSL------MEQVSGVEAFLQASQPPD 1128
+PP P P +P P G + +L +S F +++PP
Sbjct: 203 -------SPPVP-GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF--SNRPPL 252
Query: 1129 PHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEG 1188
P ++ + P P P + P H A
Sbjct: 253 PPTPSRALDDKPP------------------PPPPPVGNRPSIHREA------------- 281
Query: 1189 GVGVGPGGGDEPP--TSPR---QLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRET 1243
V P ++PP ++PR Q PP P RP P P G+ +P +
Sbjct: 282 -VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS---SSGNDETPRLPQR 337
Query: 1244 SAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSS-------WGRTRSLGGLISA 1296
+ + + R P PP + PPPP+ P +S R S + A
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 1297 VGVGSTGGGCGGPGPGALPP 1316
+ G P G PP
Sbjct: 398 TPQLPSRSGVDSPRSGPRPP 417
Score = 37.4 bits (85), Expect = 0.097
Identities = 59/242 (24%), Positives = 81/242 (33%), Gaps = 41/242 (16%)
Query: 367 GDGGAAAGAAAAGARPVSVAGS-----PLSPGPVRAPLSRSHTLSGGCGGRGS--KVALL 419
G+ G A G + P+S + PL P P RA + G R S + A+
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP 283
Query: 420 PAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQ 479
P P + PP ++P S+S PPP P PP P G +
Sbjct: 284 PPP-----------PQNNKPPVPSTPRP--SASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330
Query: 480 RPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEF 539
P + S S S P S G P P S PP RD G
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLP------------PPPSERPPPPVRDPPGRS-- 376
Query: 540 YGYMTMDRPLSHCGRSYR------RVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSA 593
G + P+S G + R ++ + D R + P+ P P P S
Sbjct: 377 -GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435
Query: 594 SL 595
S+
Sbjct: 436 SI 437
Score = 37.0 bits (84), Expect = 0.13
Identities = 42/142 (29%), Positives = 57/142 (40%), Gaps = 16/142 (11%)
Query: 369 GGAAAGAAAAGARPVSVAGSPLSP--GPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQ 426
GG+ G R S + P SP GP R P+ SG + ++ +P
Sbjct: 122 GGSRPPLLPPGGR--STSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNR---MPPPRPDV 176
Query: 427 HSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHG-PGQRPSSGS 485
S+ S+P PP ++P + SS H GS P P GP P P P PG R G+
Sbjct: 177 GSKPDSIP----PPVPSTPRPIQSSP-HNRGSPPVPGGPRQPSPGPTPPPFPGNR---GT 228
Query: 486 ASASGSPSDPGFMSLDEYGSSP 507
A GS S + + P
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRP 250
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 71.2 bits (173), Expect = 6e-12
Identities = 87/353 (24%), Positives = 122/353 (34%), Gaps = 42/353 (11%)
Query: 791 GGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQA 850
GG P G+ G + +P+ + P GR + P + PG
Sbjct: 95 GGPP--GLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 851 AS-AFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPL 909
S +GP +P +P P G +P+ P + P S H
Sbjct: 153 PSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI---------PPPVPSTPRPIQSSPHNRGS 203
Query: 910 PPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDS 969
PP P P + PG PP P +A S+ SP SS SS
Sbjct: 204 PPVPGGPRQ------PSPGPT-PPPFPGNRGTALGGGSI--RQSPLSS--------SSPF 246
Query: 970 RQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSL 1029
R PL + P P P + + P + PP+P P S SS
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 1030 QPPPPPPAPGELYRLPPASA--VATAQGPGAASSLSSDT---GDNGDYTEMAFGVAATPP 1084
PPPPPP+ LPP+S+ T + P SLSS T G + + PP
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPP 366
Query: 1085 QPI--------AAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDP 1129
P+ PP P +R S + + + SGV++ +PP P
Sbjct: 367 PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLP 419
Score = 53.5 bits (127), Expect = 1e-06
Identities = 81/303 (26%), Positives = 108/303 (35%), Gaps = 57/303 (18%)
Query: 843 ATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRA-----VRPTRLSLEG 897
+TP P Q++ P P P PSP G P F G RG A +R + LS
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSP----GPTPPPFPGNRGTALGGGSIRQSPLSSSS 244
Query: 898 -------LPSLPS--MHEYPLPPEP---KSPGEYINIDFGEPGARLSPPAPPLLASAASS 945
LP PS + + P PP P P + P PP P +ASS
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS 304
Query: 946 SSLLSASSPASSLGSGTPGTSS--DSRQRSPLSDYMNLDFSSPKSPKPGA-------PSG 996
+ P+ P +SS D R P + ++L S+P P PG PS
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN-LSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 997 HPVGSLDGLLSPEASSPYPPLPP----------------RPSAS----PSSSLQPPPPPP 1036
P + P S P PP PP PS S P S +PP PP
Sbjct: 364 RPPPPVRD--PPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPD 421
Query: 1037 APGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAA 1096
P PP +T+ G S D ++ Y + PP+P K +
Sbjct: 422 RPSA--GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDL--PPPEPYVQTTKSYPS 477
Query: 1097 RVA 1099
++A
Sbjct: 478 KLA 480
Score = 43.5 bits (101), Expect = 0.001
Identities = 82/380 (21%), Positives = 116/380 (30%), Gaps = 78/380 (20%)
Query: 959 GSGTPGTSSDSRQRSP-LSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYP-P 1016
G G PG + P L N D S S P P G S P +P P
Sbjct: 94 GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153
Query: 1017 LPPRPSA--SPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTE 1074
P S P + PPP P + +PP P + S + G
Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPV-------PSTPRPIQSSPHNRG---- 202
Query: 1075 MAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSL------MEQVSGVEAFLQASQPPD 1128
+PP P P +P P G + +L +S F +++PP
Sbjct: 203 -------SPPVP-GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF--SNRPPL 252
Query: 1129 PHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEG 1188
P ++ + P P P + P H A
Sbjct: 253 PPTPSRALDDKPP------------------PPPPPVGNRPSIHREA------------- 281
Query: 1189 GVGVGPGGGDEPP--TSPR---QLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRET 1243
V P ++PP ++PR Q PP P RP P P G+ +P +
Sbjct: 282 -VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS---SSGNDETPRLPQR 337
Query: 1244 SAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSS-------WGRTRSLGGLISA 1296
+ + + R P PP + PPPP+ P +S R S + A
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 1297 VGVGSTGGGCGGPGPGALPP 1316
+ G P G PP
Sbjct: 398 TPQLPSRSGVDSPRSGPRPP 417
Score = 37.4 bits (85), Expect = 0.097
Identities = 59/242 (24%), Positives = 81/242 (33%), Gaps = 41/242 (16%)
Query: 367 GDGGAAAGAAAAGARPVSVAGS-----PLSPGPVRAPLSRSHTLSGGCGGRGS--KVALL 419
G+ G A G + P+S + PL P P RA + G R S + A+
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP 283
Query: 420 PAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQ 479
P P + PP ++P S+S PPP P PP P G +
Sbjct: 284 PPP-----------PQNNKPPVPSTPRP--SASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330
Query: 480 RPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEF 539
P + S S S P S G P P S PP RD G
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLP------------PPPSERPPPPVRDPPGRS-- 376
Query: 540 YGYMTMDRPLSHCGRSYR------RVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSA 593
G + P+S G + R ++ + D R + P+ P P P S
Sbjct: 377 -GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST 435
Query: 594 SL 595
S+
Sbjct: 436 SI 437
Score = 37.0 bits (84), Expect = 0.13
Identities = 42/142 (29%), Positives = 57/142 (40%), Gaps = 16/142 (11%)
Query: 369 GGAAAGAAAAGARPVSVAGSPLSP--GPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQ 426
GG+ G R S + P SP GP R P+ SG + ++ +P
Sbjct: 122 GGSRPPLLPPGGR--STSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNR---MPPPRPDV 176
Query: 427 HSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHG-PGQRPSSGS 485
S+ S+P PP ++P + SS H GS P P GP P P P PG R G+
Sbjct: 177 GSKPDSIP----PPVPSTPRPIQSSP-HNRGSPPVPGGPRQPSPGPTPPPFPGNR---GT 228
Query: 486 ASASGSPSDPGFMSLDEYGSSP 507
A GS S + + P
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRP 250
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 71.2 bits (173), Expect = 6e-12
Identities = 210/917 (22%), Positives = 295/917 (32%), Gaps = 226/917 (24%)
Query: 391 SPGPVRAPLSRSHTLS--GGCGGRGSKVALLPAGGALQHSRSMSMPVAHS--PPA----- 441
S G PL+R +L+ G GG G L PA + +S + H+ PP
Sbjct: 309 STGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVA 368
Query: 442 ---------------ATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSA 486
+ SP S+ S S S P P H PSS S
Sbjct: 369 LGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRH--------------PSSSSD 414
Query: 487 SASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMD 546
+ S S S +S SS G ++ S + PP + G G G G T +
Sbjct: 415 TWSHSQSSDTIVSDGSTLSSKGGSE---GQPESSTASNSVVPPPQGGSGRGSPSGGSTAE 471
Query: 547 RPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFS 606
+ RS ++SG + LRK +RP P P R T S
Sbjct: 472 ASDTLSIRSSGQLSGRSV-----SLRK---------LKRPPPPP-----------RRTHS 506
Query: 607 -GSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAA-LAG 664
G P P P P PE ++ ++ + GA P P + + G
Sbjct: 507 LHQRGLAVPDGPLGLP-----PKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPG 561
Query: 665 SGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPA-PTSAAGRTFPAS 723
G R +P++ L P + ++ + P+ P G A P ++ G+ P
Sbjct: 562 LSPGGSRRPP---------RSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPK 612
Query: 724 GGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGK----LLPNGDYLNVSPSDAVTTGT 779
+ +S S + C S +D L P GD + P V
Sbjct: 613 --PERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670
Query: 780 PPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERL 839
P P +P P + P P + S Q S P
Sbjct: 671 SP--------PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQ----SPPT--------- 709
Query: 840 EPQATPGPSQAASAFGAGPTQPPHPVVPS--PVRPSGGRPEGFLGQRGRAVRPTRLSLEG 897
PQ T P Q + + PP P PS P P +PE +
Sbjct: 710 -PQTTLTPLQESPVISKDQSPPPSP-PPSYHPPPPPTKKPE---------------VVVE 752
Query: 898 LPSLPSMHEYPL------PPEPKSPGE--YINIDFGEPGARLSPPAPPLLASAASSSSLL 949
PS E PL PP P +P E DF P A P A + S L+
Sbjct: 753 APSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812
Query: 950 SASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPE 1009
SSPA+S S T L P SP P
Sbjct: 813 --SSPAASSSSATA-----------------LQIQPPGSPDP------------------ 835
Query: 1010 ASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDN 1069
PP PP P +P+SS APG + +LP V ++G G
Sbjct: 836 -----PPAPPAP--APASS--------APGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880
Query: 1070 GDYTEM-------AFGVAATPPQPIAAPPKP-------EAARVASPTSGVKRLSLMEQVS 1115
+M A G A TP +AP KP A+ V +P+SG+ ++ S
Sbjct: 881 PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACS 940
Query: 1116 -GVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNS 1174
L ++QP P P S+ PVSP + +R+
Sbjct: 941 LAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000
Query: 1175 ASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGS 1234
A + ++S ++ PP +P++ APP P R + G P P S
Sbjct: 1001 AELRSISEQR---------------PPQAPKKSPKAPP--PVARKPSVGVPP-----PAS 1038
Query: 1235 GGSPMRRETSAGFQNGL 1251
P +A NGL
Sbjct: 1039 PSYPRAEPLTAPPTNGL 1055
Score = 70.9 bits (172), Expect = 8e-12
Identities = 127/495 (25%), Positives = 177/495 (35%), Gaps = 96/495 (19%)
Query: 841 PQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPE-----GFLGQRGRAVRPTRLSL 895
P+ T PS S+ PT PP + P P +P L G +V + SL
Sbjct: 574 PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSL 633
Query: 896 EGLPSLPSMHE-------------YPLPPEPKSPGEYINIDFGEPGARLSP-PAPPLLAS 941
S P+ + + +PP PK P + P SP PA P LA+
Sbjct: 634 CSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF----SPPPSKPRSPNPAAPALAA 689
Query: 942 AASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGS 1001
A +S ++ AS TP T+ Q SP+ ++ D S P SP PS HP
Sbjct: 690 PAVVPGPVS-TTDASPQSPPTPQTTLTPLQESPV---ISKDQSPPPSP---PPSYHP--- 739
Query: 1002 LDGLLSPEASSPYPPLPPRPSASPSSS--LQ----PPPPPPAPGE----LYRLPPAS--- 1048
P + + PSAS ++ LQ PPPPPPAP E + PP
Sbjct: 740 -----PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAF 794
Query: 1049 -AVATAQGPGAASS---LSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSG 1104
+VA+ + G + S +SS + T + +P P APP P A +S
Sbjct: 795 FSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPP-PAPPAP--APASSAPGH 851
Query: 1105 VKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPS 1164
V +L E V + PP GA ++ R S T + PS
Sbjct: 852 VAKLPQKEPV----GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT-PALGPS 906
Query: 1165 FAHNPKRH------------NSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPP 1212
P R +S V L+ S + G P P + +P P
Sbjct: 907 APQKPLRRALSGRASPVPAPSSGLHAAVRLKACS---LAASEGLSSAQPNGPPEAEPRP- 962
Query: 1213 LAPQGRPWTPGQPGGLVGCPGSG----GSPMRRETSAGFQNGLNYIAIDVREEPGLPPQ- 1267
P +P + GS P+ ET A Q L + E+ PPQ
Sbjct: 963 ------PQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQ--RPPQA 1014
Query: 1268 ----PQPPPPPLPQP 1278
P+ PPP +P
Sbjct: 1015 PKKSPKAPPPVARKP 1029
Score = 63.9 bits (154), Expect = 1e-09
Identities = 111/470 (23%), Positives = 150/470 (31%), Gaps = 102/470 (21%)
Query: 881 LGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLA 940
L QRG AV L GLP P + P P P + G G GA +P P
Sbjct: 507 LHQRGLAVPDGPL---GLPPKPERKQQPQLPRPPTTG-------GSEGAGAAPCPP---- 552
Query: 941 SAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVG 1000
+PA+ S PG S +R P S L SS S + G P+
Sbjct: 553 ------------NPAN---SWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPT----- 592
Query: 1001 SLDGLLSPEASSPYPPLPPRPSASPSSSL-QPPPPPPAPGELYRLPPASAVATAQGPGAA 1059
LPP+ A P +S + PP P R P AS ++ ++
Sbjct: 593 ----------------LPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSS 636
Query: 1060 SSLSSDTGDNGDYTEMAFGVA-ATPPQP-IAAPPKPEAARVASPTSGVKRLSLMEQVSGV 1117
SS + + +G G PP P + AP P ++ SP L+ V G
Sbjct: 637 SSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGP 696
Query: 1118 EAFLQAS--QPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSA 1175
+ AS PP P ++ P S + P P H P
Sbjct: 697 VSTTDASPQSPPTPQTTLTPLQESP----------VISKDQSPPPSPPPSYHPPPPPTKK 746
Query: 1176 SVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWT------PGQPGGLV 1229
V +SE E P P PP AP+ + + P + V
Sbjct: 747 PEVVVEAPSASETA---------EEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSV 797
Query: 1230 GCP---GSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGR 1286
P G GSP + A + + I P PP P P P PG + +
Sbjct: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQ 857
Query: 1287 TRSLG-------------------GLISAVGVGSTGGGCGGPGPGALPPA 1317
+G L+ V + S G G P P P A
Sbjct: 858 KEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSA 907
Score = 44.7 bits (104), Expect = 6e-04
Identities = 204/976 (20%), Positives = 300/976 (30%), Gaps = 235/976 (24%)
Query: 137 RALTDLVSEGRAAAGDAPPAAAPAASCSASLPGALGGSAGAAGAEDSYGLVAPATAAYRE 196
R D GR+ APP P S ++PG GG+ A + + AT +
Sbjct: 298 RVYRDDTFVGRSTGTRAPPLTRPM---SLAVPGLTGGAGPAEPLSPAMSISPQATYLSKL 354
Query: 197 VWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFF 256
+ L P + ++ + R L RT+ L+ P+ ++R G S
Sbjct: 355 IPHAVLPP-----TVDVVALGRCSL--RTLSRCSLHSASPA------SVRSLGRFSSVSS 401
Query: 257 IEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHP 316
+ + + W + S +TI+ L + S+ Q S+A++
Sbjct: 402 PQPRSRHPSSSSDTWSHSQSS-------DTIVSDGSTLSS----KGGSEGQPESSTASNS 450
Query: 317 ISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAA 376
+ +PP Q G R S + TA D + +
Sbjct: 451 V-------------VPPPQGGSGRGSPSGG---------------STAEASDTLSIRSSG 482
Query: 377 AAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVA 436
R VS+ P P R R+H+L RG V P G + R P
Sbjct: 483 QLSGRSVSLRKLKRPPPPPR----RTHSLHQ----RGLAVPDGPLGLPPKPERKQQ-PQL 533
Query: 437 HSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR----------PSSGSA 486
PP T+ GS G+G+ P PP P L G +R PSSG +
Sbjct: 534 PRPP--TTGGS------EGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYS 585
Query: 487 SASGS-----------PSDPG---------FMSLDEYGSS-PGDLRAFCSHRSNTPESIA 525
S SG+ P+ PG SL G+S L + CS S+ S
Sbjct: 586 SQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDR 645
Query: 526 ETPPARDG-GGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQ 584
P G + + P S R + A + S T + Q
Sbjct: 646 SGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQ 705
Query: 585 R-PVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSS 643
P PQ + L E ++ S P SP +YHP P E+ S
Sbjct: 706 SPPTPQTTLTPLQESPVISKDQS----------PPPSPPPSYHPPPPPTKKPEVVVEAPS 755
Query: 644 SSNLG----ADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAA 699
+S D + P P A + +S A P++ A
Sbjct: 756 ASETAEEPLQDPNWPPPPPPA------------PEEQDLSMADFPPPEE---------AF 794
Query: 700 AAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGK 759
+V S PAGP SG SSPA SS + +
Sbjct: 795 FSVASPEPAGP------------SGSPELVSSPAASSSSATAL----------------Q 826
Query: 760 LLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGD 819
+ P G SP P SA H P + GC GG
Sbjct: 827 IQPPG-----SPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKG------------GGP 869
Query: 820 SDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEG 879
+ V +L+ RL PG + + + P +P + P G
Sbjct: 870 PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSG 929
Query: 880 FLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLL 939
AVR SL L S +P P P A PP P
Sbjct: 930 L----HAAVRLKACSLAASEGLSS-------AQPNGP----------PEAEPRPPQSP-- 966
Query: 940 ASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPV 999
A+++S + S S L + QR+ +++ ++ P
Sbjct: 967 --ASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRP------------- 1011
Query: 1000 GSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAA 1059
P+A P PP + PS + PP P P R P +A T P
Sbjct: 1012 --------PQAPKKSPKAPPPVARKPSVGVPPPASPSYP----RAEPLTAPPTNGLPHTQ 1059
Query: 1060 SSLSSDTGDNGDYTEM 1075
+ +NG ++
Sbjct: 1060 DRTKRELAENGGVLQL 1075
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 70.5 bits (171), Expect = 1e-11
Identities = 141/591 (23%), Positives = 195/591 (32%), Gaps = 94/591 (15%)
Query: 787 ALHPGGEPLRGVPG----------CCYSSLPRSYKAPYTCG------GDSDQYVLMSSPV 830
AL PGG L G C +S P + A C G +D Y SP+
Sbjct: 190 ALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTY---QSPL 246
Query: 831 GRILEEER--------------LEPQATPGPSQAASAFGAGPTQPPHPVVPS-PVRPSGG 875
G + ++ LE T P+ + G GP P P+ P R S
Sbjct: 247 GPLFSQDSGRPFTFQSDLALLGLENLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPT 306
Query: 876 RPEGFLGQRGRA---VRPTRLSLEGL--PSLP-SMHEYPLPPEPKS--PGEYINIDFGEP 927
P + G A + P +LS P LP S+ P P + P + I
Sbjct: 307 NPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPK 366
Query: 928 GARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPK 987
P AP S ++P+S S P P+ ++ P
Sbjct: 367 SLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPI 426
Query: 988 SPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPA 1047
PG P P + L P SS P+P + P A ++ PP
Sbjct: 427 QRNPGMPRPPPPSTRP--LPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPF 484
Query: 1048 SAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKR 1107
+A++++ P S+ S+ T + + P+ A P P +A PT K
Sbjct: 485 TALSSSPAPTPGSTRST----RPPATMVPPTSGTSTPRTAPAVPTPGSA----PTGSKKP 536
Query: 1108 LSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSS----ETFSSTTTVTPVSP 1163
+ + S + + P P R K R P S + TT ++P
Sbjct: 537 IG--SEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAP 594
Query: 1164 S-FAHNPKRHNSASVENVSLRKSS-----------EGGVGV-GPGGGDEPPTSPRQLQPA 1210
+ F + R S+ L S+ +G G+ GP G P P P
Sbjct: 595 AQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPR 654
Query: 1211 PPLAPQGRPWTPGQPG--GLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQP 1268
P P G P PG PG G G PG SP + A GL PGL P
Sbjct: 655 GPPGPYGNPGLPGPPGAKGQKGDPGL--SPGKAHDGAKGDMGL----------PGLSGNP 702
Query: 1269 QPP--------PPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGP 1311
PP P P PG++ G S G G G G PGP
Sbjct: 703 GPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAK-GYPGRQGLPGPVGDPGP 752
Score = 59.7 bits (143), Expect = 2e-08
Identities = 218/1011 (21%), Positives = 298/1011 (29%), Gaps = 177/1011 (17%)
Query: 367 GDGGAAAGAAAAGARPVSVAGSPLSP-------GPVRAPLSRSHTLSGGCGGRGSKVALL 419
G G A A +P SP +P GP + PL L + +L
Sbjct: 285 GRGPRGTVAPATPTKPQRT--SPTNPHQHMAVGGPAQTPL-----LPAKLSASNALDPML 337
Query: 420 PA--GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGP 477
PA GG+ + R + + A P SL + S S P PHP
Sbjct: 338 PASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPT--------- 388
Query: 478 GQRPSSGSASASGSPSD----PGFMSLDEYGSSPGD--LRAFCSHRSNTPESIAETPPAR 531
Q+ + S + S P+ P + S P + ++ P S PP
Sbjct: 389 -QKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTT 447
Query: 532 DGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPS 591
+P+ R+ +++ A++ T P P P
Sbjct: 448 SSS-----------KKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPG 496
Query: 592 S--ASLDEYTLMRATFSGSAGRLCPSCPA--SSPKVAYHPYPEDYGDIEIGSHRSSSSNL 647
S ++ T++ T S R P+ P S+P + P IGS S +
Sbjct: 497 STRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKP---------IGSEASKKAGP 547
Query: 648 GADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGP 707
+ P P G + D P Q P A A + S+
Sbjct: 548 KSS----PRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSS-- 601
Query: 708 AGPAPTSAAGRTFPASGG----------GYKASSPAESSPEDSGYMRMWCGSKLSMEHAD 757
P PTS+ F +G G K P G + A
Sbjct: 602 --PRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLP--------GIPGAR 651
Query: 758 GKLLPNGDYLNVS---PSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPY 814
G P G Y N P A P H G + G+PG + P K
Sbjct: 652 GPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHK 711
Query: 815 TCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGA-GPTQPPHPVVPSPVRPS 873
G P G E+ + P+ +PG G GP P P R
Sbjct: 712 GYPG----------PAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGP---KGSRGY 758
Query: 874 GGRP-----EGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPE-PKSPGEYINIDFGEP 927
G P G G+RG P + G+P P + PP +PGE G P
Sbjct: 759 IGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGE-----LGLP 813
Query: 928 GARLSPPAPPLLASAASSSSLLSASSPASSLGS----GTPGTSSDSRQRSPLSDYMNLDF 983
G PP P L + P G G PG D ++ + F
Sbjct: 814 G----PPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGF 869
Query: 984 SSPKSPK--PGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGEL 1041
K + PG P G + + S +P PP P P PP P +
Sbjct: 870 QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPG-PPGPEGFPGDI--GPPGDNGPEGM 926
Query: 1042 YRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASP 1101
P A + PG L + GD G P P +P V
Sbjct: 927 KGKPGARGL-----PGPRGQLGPE-GDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGE 980
Query: 1102 TSGVKRLSLMEQVSGVEAFLQASQPPD--PHRGAKVIRADPQ-GGRRRHSSETFSSTTTV 1158
R + + G F+ P +G + + P G +
Sbjct: 981 PGDPGRPGPVGE-QGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMG 1039
Query: 1159 TPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGR 1218
TP P P + R+ GP G D P P PQGR
Sbjct: 1040 TPGEPGPQGPPGSRGPPGMRGAKGRR--------GPRGPDGPAGEQGSRGLKGPPGPQGR 1091
Query: 1219 PWTPGQPG-----------GLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLP-- 1265
P PGQ G G G PG G P + GLP
Sbjct: 1092 PGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTK---------------------GLPGE 1130
Query: 1266 PQPQPPPPPLPQPGDKSSWGRTRSLG--GLISAVGVGSTGGGCGGPGPGAL 1314
P PQ P P+ PG+ G ++G GL G+ G G PG L
Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181
Score = 47.8 bits (112), Expect = 7e-05
Identities = 221/996 (22%), Positives = 287/996 (28%), Gaps = 192/996 (19%)
Query: 333 PSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGA----AAAGARPVSVAGS 388
P+ T RS PP + S+ R A G A G+ + ++ S
Sbjct: 491 PAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSS 550
Query: 389 PLSPGPVR-APLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGS 447
P P P+R +R LS + P+ Q S+ + + +P S
Sbjct: 551 PRKPVPLRPGKAARDVPLSD--------LTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP 602
Query: 448 LSSSSG----HGSGSYP-----PPPGPH-------PPLPHPLHHGPGQRPSSGSASASGS 491
+SSG H +GS P PPGP PP L PG R G G+
Sbjct: 603 RPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGN 662
Query: 492 PSDPGFMSLD----EYGSSPGDLRAFCSHRSNTPESIAET-PPARDGGGGGEFYGYMTMD 546
P PG + G SPG P PP R G G
Sbjct: 663 PGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKG--------YP 714
Query: 547 RPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQR---PVPQPSSASLDEYTLMRA 603
P H G G + G + P RQ PV P Y +
Sbjct: 715 GPAGHPGEQ-----GQPGPEGSPGAKGY------PGRQGLPGPVGDPGPKGSRGYIGLPG 763
Query: 604 TFS--GSAG-RLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA 660
F GS G R P P K+ +P +G+ + LG +P PG
Sbjct: 764 LFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELG-----LPGPPGV 818
Query: 661 -ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAG---------- 709
L G D + P PK + + G G
Sbjct: 819 PGLIG---------DLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGF 869
Query: 710 ---------PAPTSAAGRTFPASGGGYKASSPAESSPEDSGY--------------MRMW 746
P A G+ P G K S P G+ M+
Sbjct: 870 QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGK 929
Query: 747 CGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSL 806
G++ + G+L P GD + P A P PG + ++G PG
Sbjct: 930 PGAR-GLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPG------ 982
Query: 807 PRSYKAPYTCGGDSDQYVLMSSP--VGRILEEERLEPQATPGPSQAASAFGAGPTQPPHP 864
P G L+ P VG + + P PGP + G P P
Sbjct: 983 DPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGM-PGGMGTP 1041
Query: 865 VVPSPVRPSGGR-PEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSP-GEYINI 922
P P P G R P G G +GR P P P GE +
Sbjct: 1042 GEPGPQGPPGSRGPPGMRGAKGRRG---------------------PRGPDGPAGEQGSR 1080
Query: 923 DF-GEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNL 981
G PG + P P A L S P SG PGT
Sbjct: 1081 GLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTK--------------- 1125
Query: 982 DFSSPKSPKPGAPSG--HPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPG 1039
P P P P G P G + G P + P LP A L P P G
Sbjct: 1126 --GLPGEPGPQGPQGPIGPPGEM-GPKGPPGAVGEPGLP--GEAGMKGDLGPLGTPGEQG 1180
Query: 1040 ELYRL--PPASAVATAQGPGAASSLSSDTGDNGDYTEMA-FGVAATPPQPIAAPPKPEAA 1096
+ + P + GP D G +G++ E G+ P PP
Sbjct: 1181 LIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPP--GPPGVTGV 1238
Query: 1097 RVASPTSGVKRLSLMEQVSGVEAFL----QASQPPDPHRGAKVIRADPQG-----GRRRH 1147
R SG + G + + + P DP P G G R
Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDP---------GPPGTPGPKGSRGS 1289
Query: 1148 SSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQL 1207
T + P A K +G G G + PP P
Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG-EDGKAEGPPGPPGDR 1348
Query: 1208 QPAPPLAPQGRPWTPGQPG-----GLVGCPGSGGSP 1238
P +G P PG PG GL G PG G P
Sbjct: 1349 GPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQP 1384
Score = 45.1 bits (105), Expect = 5e-04
Identities = 122/521 (23%), Positives = 159/521 (30%), Gaps = 82/521 (15%)
Query: 845 PGP-SQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPS 903
PGP Q GP PP G P G GQ GR P R L+G+ P
Sbjct: 936 PGPRGQLGPEGDEGPMGPP------------GAP-GLEGQPGRKGFPGRPGLDGVKGEPG 982
Query: 904 MHEYPLPPEPKSPGEYINIDFGEPG--------ARLSPPAPPLLASAASSSSLLSA-SSP 954
P P + +I + GEPG + PP P + + +P
Sbjct: 983 DPGRPGPVGEQGFMGFIGL-VGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTP 1041
Query: 955 ASSLGSGTPGTSSDSRQRS------------PLSDYMNLDFSSPKSP--KPGAPSGHPVG 1000
G PG+ R P + + P P +PG P V
Sbjct: 1042 GEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVA 1101
Query: 1001 SLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPA--------PGELYRLPPASAVAT 1052
G L S +P +P PS P + P P P PGE+ P AV
Sbjct: 1102 GERGHLG---SRGFPGIPG-PSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGE 1157
Query: 1053 AQGPGAASSLSSDTGDNGDYTEMAF-GVAATPP-QPIAAPPKPEAARVASPTSGVKRLSL 1110
PG A + D G G E G P + + P P+ + G
Sbjct: 1158 PGLPGEAG-MKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDG--- 1213
Query: 1111 MEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSET-----------FSSTTTVT 1159
G E + PP P V + + G++ T
Sbjct: 1214 EHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPG 1273
Query: 1160 PVSPSFAHNPK-RHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGR 1218
P PK S R ++G G+ G + P PP P+G
Sbjct: 1274 DPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPL----GPP-GPKGE 1328
Query: 1219 PWTPGQPGGLVGCPGSGG--SPMRRETSAGFQNGLNYIAID----VREEPGLPPQPQPPP 1272
G+ G G PG G P+ G Y + +R +PG QP P
Sbjct: 1329 KGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQP-GHP 1387
Query: 1273 PPLPQPGDKSSWGRTRSLG--GLISAVGVGSTGGGCGGPGP 1311
P PG K S G G G A G G G PGP
Sbjct: 1388 GPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGP 1428
Score = 44.3 bits (103), Expect = 8e-04
Identities = 92/428 (21%), Positives = 133/428 (31%), Gaps = 93/428 (21%)
Query: 902 PSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSG 961
P+ P P +P +++ + P PLL + S+S+ L PAS GS
Sbjct: 294 PATPTKPQRTSPTNPHQHMAVG--------GPAQTPLLPAKLSASNALDPMLPASVGGS- 344
Query: 962 TPGTSSDSRQRSPLSDYMNLDFSSPKSPK--PGAPSGHPVGSLDGLLSPEASSPYPPLPP 1019
+R P + + ++ K PK P PS P S+ + SP + P
Sbjct: 345 -------TRTPRPAAAQPSQKITATKIPKSLPTKPSA-PSTSIVPIKSPHPTQKTAPSSF 396
Query: 1020 RPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGV 1079
SA P+ PP P P + R PA + PG
Sbjct: 397 TKSALPTQKQVPPTSRPVPARVSR--PAEK-PIQRNPGMPRP------------------ 435
Query: 1080 AATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRAD 1139
PP PP +++ PT + S + ++ P P A
Sbjct: 436 --PPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAP 493
Query: 1140 PQGGRRRHSSETF-------SSTTTVTPVSPSFAHNP----KRHNSASVENVSLRKSSEG 1188
G R +ST P P+ P K S + + + S
Sbjct: 494 TPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRK 553
Query: 1189 GVGVGPG-GGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGF 1247
V + PG + P S +P+P + TP LV P S R TS+G+
Sbjct: 554 PVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPA----LVLAPAQFLSSSPRPTSSGY 609
Query: 1248 QNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCG 1307
+ G P P PP P+ G CG
Sbjct: 610 S---------IFHLAGSTPFPLLMGPPGPK--------------------------GDCG 634
Query: 1308 GPGPGALP 1315
PGP LP
Sbjct: 635 LPGPPGLP 642
Score = 33.5 bits (75), Expect = 1.4
Identities = 93/395 (23%), Positives = 115/395 (29%), Gaps = 85/395 (21%)
Query: 869 PVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEY-----PL-PPEPKSP-GEYIN 921
P P P+G G G P R+ +G P L + PL PP PK GE
Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQ-- 1332
Query: 922 IDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGS-------GTPGTSSDSRQRSP 974
GE G PP PP G G PG P
Sbjct: 1333 ---GEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGP 1389
Query: 975 LS-----DYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSP---------EASSPYPPLPPR 1020
+ K K GAP V L GL P E + LP R
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGR 1449
Query: 1021 PSASPSSSLQPP---PPPPAPGELYRLPPASAVATAQGPGA---ASSLSSDTGDNGDY-T 1073
+ Q P P P P + + AQGP S L G G T
Sbjct: 1450 DGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGT 1509
Query: 1074 EMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGA 1133
E G+ +P + ++ + P G+ PP G
Sbjct: 1510 EGRTGLPGNQGEPGSKGQPGDSGEMGFP--------------GMAGLFGPKGPPGDI-GF 1554
Query: 1134 KVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGV- 1192
K I+ P+G E + + PS PK K S G G+
Sbjct: 1555 KGIQG-PRGPPGLMGKEGIVGPLGI--LGPSGLPGPKGD-----------KGSRGDWGLQ 1600
Query: 1193 GPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGG 1227
GP G P P+GRP PG PGG
Sbjct: 1601 GPRG---------------PPGPRGRPGPPGPPGG 1620
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 69.7 bits (169), Expect = 2e-11
Identities = 98/363 (26%), Positives = 123/363 (33%), Gaps = 70/363 (19%)
Query: 931 LSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPK 990
L PP PP A S P GS P S + PL P P
Sbjct: 138 LIPPPPPGPAPGPPQD----ISEPPG--GSPLPSPPSTAPPPPPL-------LLEPPPPP 184
Query: 991 PGAPSGHPVGSLDGLLSPEA-SSPYPPLPPR--PSASPSSSLQPPPPP-PAPGELYRLPP 1046
AP PV L+ L P SSP P PP P A P + L PPPPP PAP PP
Sbjct: 185 SMAPPPPPV--LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA-----PP 237
Query: 1047 ASAVATAQG-----PGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASP 1101
A A G PG + SD NG E AT P +P +P+ + +
Sbjct: 238 APASPHTVGTRLFPPGGVTKWKSDVALNGRQAE------ATRASPPRSPAEPKGSALGPN 291
Query: 1102 TSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPV 1161
+V PP P R + + + Q R+ T + + + P+
Sbjct: 292 PEPHLTFPRSFKVP----------PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL-PL 340
Query: 1162 SPSFAHNP-------KRHNSASVENVSLRKSSEGGVGVGPGGGDE----PPTSPRQLQPA 1210
PSF P + + + +G DE PP +P PA
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA 400
Query: 1211 PPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQP 1270
PPL P P P P + C P AGF P L P+P P
Sbjct: 401 PPLPPPAPPLPPAAPP--LPCAQKAAHP-----PAGFTK------TPKSSSPALKPKPNP 447
Query: 1271 PPP 1273
P P
Sbjct: 448 PSP 450
Score = 66.2 bits (160), Expect = 2e-10
Identities = 82/303 (27%), Positives = 107/303 (35%), Gaps = 51/303 (16%)
Query: 991 PGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPP-APGELYRLPPASA 1049
P P G G + P SP P P P L+PPPPP AP PP
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP------PPPPV 193
Query: 1050 VATAQGPGAASSLSSDTGDN--GDYTEMAFGVAATPPQPIAAPPKPEAARVAS----PTS 1103
+ P SS S T + +AF PP P APP P + P
Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG 253
Query: 1104 GVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSE---TFSSTTTVTP 1160
GV + ++G +A + PP A+P+G + E TF + V P
Sbjct: 254 GVTKWKSDVALNGRQAEATRASPPRS-------PAEPKGSALGPNPEPHLTFPRSFKVPP 306
Query: 1161 VSPSFAHNPKRHNSASVENV-SLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRP 1219
+ P R +S V+ + EG P PP+ ++PA + P P
Sbjct: 307 PT------PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSF--HIRPASQVYPDRAP 358
Query: 1220 WTPGQPGGL----VGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPL 1275
P PG L P G S + + AG P PP P PP PPL
Sbjct: 359 -EPDCPGELKATAPASPRLGQSQSQADERAG-------------TPPPAPPLP-PPAPPL 403
Query: 1276 PQP 1278
P P
Sbjct: 404 PPP 406
Score = 46.6 bits (109), Expect = 2e-04
Identities = 204/921 (22%), Positives = 308/921 (33%), Gaps = 163/921 (17%)
Query: 434 PVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPS 493
P + +PP +LS S S P PP PP P P P A A +P+
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAP--PPPPVPAPAPPAPA 240
Query: 494 DPGFMSLDEYGSSPGDLRAFCSH---RSNTPESIAETPPARDGGGGGEFYG-----YMTM 545
P + + PG + + S E+ +PP G G ++T
Sbjct: 241 SPHTVGTRLF--PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF 298
Query: 546 DRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVP-----QPSSASLDEYTL 600
R + R S Q+ RK + + P+P +P+S +
Sbjct: 299 PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPD--- 355
Query: 601 MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA 660
RA G L + PA SP++ S + G P+ P A
Sbjct: 356 -RAPEPDCPGELKATAPA-SPRLGQ-------------SQSQADERAGTPPPAPPLPPPA 400
Query: 661 ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAG----PAGPAPTSAA 716
P+ P + P P A AA P AG P +P +
Sbjct: 401 P---------------PLPPPAPPLPP--AAPPLPCAQKAAHPPAGFTKTPKSSSP-ALK 442
Query: 717 GRTFPASGGGYKASSPAE-SSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAV 775
+ P S +S+P + P +R + L + + L + V+P
Sbjct: 443 PKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE 502
Query: 776 TTGTP--PDFFSAALHPGGEPLRGVP--GCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVG 831
P P+ + P + GVP SSL + AP + S Y+ SP
Sbjct: 503 GKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAP-SLTLPSVDYIPQDSPTP 561
Query: 832 RILE-EERLEPQ-ATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVR 889
+ + LE + ++ +A + G+ P +P R GGR + + G
Sbjct: 562 SVRQIRNELEARLSSAAEKEAKPSIGSLPPKP---------RLEGGR----ICENG--AD 606
Query: 890 PTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLL 949
+LS +LP LP P + P A P PP ++L
Sbjct: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI-PPKATPEPAIPP-------KATLW 658
Query: 950 SASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPE 1009
A+ P ++LG TP + S +PL +S + P S L E
Sbjct: 659 PATPPKATLGPATP-LKATSGPTTPLKATSGPAIASTATTLPTTTS---------QLMAE 708
Query: 1010 ASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATA-----QGPGAA----- 1059
S P +P++ S+ +P E RLP A ++A PG
Sbjct: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCL 768
Query: 1060 -------SSLSSDTGDNGDYTEMAFGVAATPPQPI------AAPPKPEAARVASPTSGVK 1106
SSLS + +A G AA P +P+ P KP A+ A PT +
Sbjct: 769 YKPHCHQSSLSREVA--VVMPTLARGGAAGPGEPVEVKEPPGLPAKPPAS--AQPTDELL 824
Query: 1107 RL----SLMEQVSGVEAFLQASQPPDPHR--GAKVIRADPQGGRRRHSSETFSSTTTV-- 1158
R ++E+ S + L A Q R GA + R+ G R HS + +S+ ++
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 1159 ---TPVSPSFAHNPKRHNSASVEN-VSLRKSSEGGVGVG-PGGGDEPP-----TSPRQLQ 1208
TP SF PK A ++ ++ ++ G +G G E T P
Sbjct: 885 SQGTP--NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQA 942
Query: 1209 P------APPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEP 1262
P AP PQG P P P E F+ + P
Sbjct: 943 PVAWERVAPSNLPQGHP----LPKSFSSPPSPSNKREEEEEEFNFE--------VIPPPP 990
Query: 1263 GLPPQPQPPPPPLPQPGDKSS 1283
P+PP P L G +SS
Sbjct: 991 EFSNDPEPPAPALQYLGRQSS 1011
Score = 44.7 bits (104), Expect = 6e-04
Identities = 218/955 (22%), Positives = 297/955 (31%), Gaps = 196/955 (20%)
Query: 351 PPAAKCSSCRVRTASEG---DGGAAAGAAAAGARPVSVAGSPLSPG-PVRAPLSRSHTLS 406
P + SS V+ A E + GA A + P S P S P RAP
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAP-------E 359
Query: 407 GGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPH 466
C G A PA L S+S + A +PP A PP P P
Sbjct: 360 PDCPGELKATA--PASPRLGQSQSQADERAGTPPPA-----------------PPLPPPA 400
Query: 467 PPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAE 526
PPLP P P P A + P P + SSP L+ +PE+ A
Sbjct: 401 PPLPPPAPPLPPAAPPLPCAQKAAHP--PAGFTKTPKSSSPA-LKP--KPNPPSPENTAS 455
Query: 527 TPPA--RDGGG--------GGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRG-----L 571
+ P RD G DR LSH R A G L
Sbjct: 456 SAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH------RPGPTVAPQSKEGKKGPRL 509
Query: 572 RKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPA-SSPKVAYHPYPE 630
++ L+ PA+ P P + GS+ + P+ + P V Y P
Sbjct: 510 PEKETLLSLPAKDTPPGVPEK-----------SLGGSSLTETEAAPSLTLPSVDYIPQDS 558
Query: 631 DYGDI-----EIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSA 685
+ E+ + SS++ A + P L G +DD P + +
Sbjct: 559 PTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNL 618
Query: 686 PKQ--------ILQPRA--------AAAAAAAVP-------------SAGPAGPAPTSAA 716
P Q LQP+A A A+P + GPA P ++
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 717 GRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKL------------LPNG 764
T + G +S A + P + S+L E G P+
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTT--------SQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
Query: 765 DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
SPS+A T SAA P P G C Y P+ + V
Sbjct: 731 ARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYK--------PHCHQSSLSREV 782
Query: 825 LMSSPV----GRILEEERLEPQATPGPSQAASAFGAGPTQP--PHPVVPSPVRPSGGRPE 878
+ P G E +E + PG A A PT HPV V G P
Sbjct: 783 AVVMPTLARGGAAGPGEPVEVKEPPG-LPAKPPASAQPTDELLRHPVTGEVV--ERGSPM 839
Query: 879 GFL------GQRGRAVRPTRLSLEGLPSLP-SMHEYPLPPEPKSPGEYINIDFGEPGARL 931
L Q+GR+V + G SLP S+ ++ E S + F G
Sbjct: 840 ALLLAARQRAQKGRSVG----AALGRSSLPGSLRDHSHQAEASS-----DSIFHSQGTPN 890
Query: 932 SPPAPPLLASAASSSSLLSASSP---ASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKS 988
S P L A S L+ P LG GT R ++ + +P +
Sbjct: 891 SFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRH-----NWTKPEPQAPVA 945
Query: 989 PKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPAS 1048
+ APS P G L SSP P R + + PPPP + P
Sbjct: 946 WERVAPSNLPQGH---PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPE----FSNDPEP 998
Query: 1049 AVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRL 1108
Q G S S + D ++ PP + P AR A G++R
Sbjct: 999 PAPALQYLGRQS--SPPRNNYSDLRQLPNAGPGAPP-ALGFSRFPAGARYAG-AGGLERF 1054
Query: 1109 SLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSE-----------TFSSTTT 1157
S G + +PHRG + P GG R S +
Sbjct: 1055 S----GGGRSLIKKRLYVGEPHRGPGL----PHGGTGRSLSSPNCFGPQPGGPEMRRVNS 1106
Query: 1158 VTPVSPSFAHNPKRHNSASVENVSLRKSSEGG---VGVGPGGGDEPPTSPRQLQP 1209
P H P+ + + K G G P G P T+ R P
Sbjct: 1107 AGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYGSP 1161
Score = 41.6 bits (96), Expect = 0.005
Identities = 88/417 (21%), Positives = 127/417 (30%), Gaps = 83/417 (19%)
Query: 765 DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
D L P G P D PGG PL P P + P
Sbjct: 136 DLLIPPPPPGPAPGPPQDISEP---PGGSPLPSPPSTAPPPPPLLLEPPPPPS------- 185
Query: 825 LMSSPVGRILE-----EERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRP-- 877
M+ P +LE P P A PP P VP+P P+ P
Sbjct: 186 -MAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244
Query: 878 --------------EGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINID 923
+ + GR TR S P+ P PEP ++
Sbjct: 245 VGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEP-------HLT 297
Query: 924 FGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDF 983
F P + PP P+ S+ A G + + R PL ++
Sbjct: 298 F--PRSFKVPPPTPVRTSSIPVQEAQEAPRKEE-------GATKKAPSRLPLPPSFHIRP 348
Query: 984 SSP----KSPKPG--------APSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQP 1031
+S ++P+P AP+ +G A +P P P P A P P
Sbjct: 349 ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAP 408
Query: 1032 PPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPP 1091
P PP AP P A A P + + A P+P PP
Sbjct: 409 PLPPAAP------PLPCAQKAAHPPAGFTKTPKSSS------------PALKPKP--NPP 448
Query: 1092 KPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPD---PHRGAKVIRADPQGGRR 1145
PE ++P + + + + A+L S+ D HR + + G++
Sbjct: 449 SPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKK 505
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 69.7 bits (169), Expect = 2e-11
Identities = 98/363 (26%), Positives = 123/363 (33%), Gaps = 70/363 (19%)
Query: 931 LSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPK 990
L PP PP A S P GS P S + PL P P
Sbjct: 138 LIPPPPPGPAPGPPQD----ISEPPG--GSPLPSPPSTAPPPPPL-------LLEPPPPP 184
Query: 991 PGAPSGHPVGSLDGLLSPEA-SSPYPPLPPR--PSASPSSSLQPPPPP-PAPGELYRLPP 1046
AP PV L+ L P SSP P PP P A P + L PPPPP PAP PP
Sbjct: 185 SMAPPPPPV--LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA-----PP 237
Query: 1047 ASAVATAQG-----PGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASP 1101
A A G PG + SD NG E AT P +P +P+ + +
Sbjct: 238 APASPHTVGTRLFPPGGVTKWKSDVALNGRQAE------ATRASPPRSPAEPKGSALGPN 291
Query: 1102 TSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPV 1161
+V PP P R + + + Q R+ T + + + P+
Sbjct: 292 PEPHLTFPRSFKVP----------PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL-PL 340
Query: 1162 SPSFAHNP-------KRHNSASVENVSLRKSSEGGVGVGPGGGDE----PPTSPRQLQPA 1210
PSF P + + + +G DE PP +P PA
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA 400
Query: 1211 PPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQP 1270
PPL P P P P + C P AGF P L P+P P
Sbjct: 401 PPLPPPAPPLPPAAPP--LPCAQKAAHP-----PAGFTK------TPKSSSPALKPKPNP 447
Query: 1271 PPP 1273
P P
Sbjct: 448 PSP 450
Score = 66.2 bits (160), Expect = 2e-10
Identities = 82/303 (27%), Positives = 107/303 (35%), Gaps = 51/303 (16%)
Query: 991 PGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPP-APGELYRLPPASA 1049
P P G G + P SP P P P L+PPPPP AP PP
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP------PPPPV 193
Query: 1050 VATAQGPGAASSLSSDTGDN--GDYTEMAFGVAATPPQPIAAPPKPEAARVAS----PTS 1103
+ P SS S T + +AF PP P APP P + P
Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG 253
Query: 1104 GVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSE---TFSSTTTVTP 1160
GV + ++G +A + PP A+P+G + E TF + V P
Sbjct: 254 GVTKWKSDVALNGRQAEATRASPPRS-------PAEPKGSALGPNPEPHLTFPRSFKVPP 306
Query: 1161 VSPSFAHNPKRHNSASVENV-SLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRP 1219
+ P R +S V+ + EG P PP+ ++PA + P P
Sbjct: 307 PT------PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSF--HIRPASQVYPDRAP 358
Query: 1220 WTPGQPGGL----VGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPL 1275
P PG L P G S + + AG P PP P PP PPL
Sbjct: 359 -EPDCPGELKATAPASPRLGQSQSQADERAG-------------TPPPAPPLP-PPAPPL 403
Query: 1276 PQP 1278
P P
Sbjct: 404 PPP 406
Score = 46.6 bits (109), Expect = 2e-04
Identities = 204/921 (22%), Positives = 308/921 (33%), Gaps = 163/921 (17%)
Query: 434 PVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPS 493
P + +PP +LS S S P PP PP P P P A A +P+
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAP--PPPPVPAPAPPAPA 240
Query: 494 DPGFMSLDEYGSSPGDLRAFCSH---RSNTPESIAETPPARDGGGGGEFYG-----YMTM 545
P + + PG + + S E+ +PP G G ++T
Sbjct: 241 SPHTVGTRLF--PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF 298
Query: 546 DRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVP-----QPSSASLDEYTL 600
R + R S Q+ RK + + P+P +P+S +
Sbjct: 299 PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPD--- 355
Query: 601 MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA 660
RA G L + PA SP++ S + G P+ P A
Sbjct: 356 -RAPEPDCPGELKATAPA-SPRLGQ-------------SQSQADERAGTPPPAPPLPPPA 400
Query: 661 ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAG----PAGPAPTSAA 716
P+ P + P P A AA P AG P +P +
Sbjct: 401 P---------------PLPPPAPPLPP--AAPPLPCAQKAAHPPAGFTKTPKSSSP-ALK 442
Query: 717 GRTFPASGGGYKASSPAE-SSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAV 775
+ P S +S+P + P +R + L + + L + V+P
Sbjct: 443 PKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE 502
Query: 776 TTGTP--PDFFSAALHPGGEPLRGVP--GCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVG 831
P P+ + P + GVP SSL + AP + S Y+ SP
Sbjct: 503 GKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAP-SLTLPSVDYIPQDSPTP 561
Query: 832 RILE-EERLEPQ-ATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVR 889
+ + LE + ++ +A + G+ P +P R GGR + + G
Sbjct: 562 SVRQIRNELEARLSSAAEKEAKPSIGSLPPKP---------RLEGGR----ICENG--AD 606
Query: 890 PTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLL 949
+LS +LP LP P + P A P PP ++L
Sbjct: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI-PPKATPEPAIPP-------KATLW 658
Query: 950 SASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPE 1009
A+ P ++LG TP + S +PL +S + P S L E
Sbjct: 659 PATPPKATLGPATP-LKATSGPTTPLKATSGPAIASTATTLPTTTS---------QLMAE 708
Query: 1010 ASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATA-----QGPGAA----- 1059
S P +P++ S+ +P E RLP A ++A PG
Sbjct: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCL 768
Query: 1060 -------SSLSSDTGDNGDYTEMAFGVAATPPQPI------AAPPKPEAARVASPTSGVK 1106
SSLS + +A G AA P +P+ P KP A+ A PT +
Sbjct: 769 YKPHCHQSSLSREVA--VVMPTLARGGAAGPGEPVEVKEPPGLPAKPPAS--AQPTDELL 824
Query: 1107 RL----SLMEQVSGVEAFLQASQPPDPHR--GAKVIRADPQGGRRRHSSETFSSTTTV-- 1158
R ++E+ S + L A Q R GA + R+ G R HS + +S+ ++
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 1159 ---TPVSPSFAHNPKRHNSASVEN-VSLRKSSEGGVGVG-PGGGDEPP-----TSPRQLQ 1208
TP SF PK A ++ ++ ++ G +G G E T P
Sbjct: 885 SQGTP--NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQA 942
Query: 1209 P------APPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEP 1262
P AP PQG P P P E F+ + P
Sbjct: 943 PVAWERVAPSNLPQGHP----LPKSFSSPPSPSNKREEEEEEFNFE--------VIPPPP 990
Query: 1263 GLPPQPQPPPPPLPQPGDKSS 1283
P+PP P L G +SS
Sbjct: 991 EFSNDPEPPAPALQYLGRQSS 1011
Score = 44.7 bits (104), Expect = 6e-04
Identities = 218/955 (22%), Positives = 297/955 (31%), Gaps = 196/955 (20%)
Query: 351 PPAAKCSSCRVRTASEG---DGGAAAGAAAAGARPVSVAGSPLSPG-PVRAPLSRSHTLS 406
P + SS V+ A E + GA A + P S P S P RAP
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAP-------E 359
Query: 407 GGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPH 466
C G A PA L S+S + A +PP A PP P P
Sbjct: 360 PDCPGELKATA--PASPRLGQSQSQADERAGTPPPA-----------------PPLPPPA 400
Query: 467 PPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAE 526
PPLP P P P A + P P + SSP L+ +PE+ A
Sbjct: 401 PPLPPPAPPLPPAAPPLPCAQKAAHP--PAGFTKTPKSSSPA-LKP--KPNPPSPENTAS 455
Query: 527 TPPA--RDGGG--------GGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRG-----L 571
+ P RD G DR LSH R A G L
Sbjct: 456 SAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH------RPGPTVAPQSKEGKKGPRL 509
Query: 572 RKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPA-SSPKVAYHPYPE 630
++ L+ PA+ P P + GS+ + P+ + P V Y P
Sbjct: 510 PEKETLLSLPAKDTPPGVPEK-----------SLGGSSLTETEAAPSLTLPSVDYIPQDS 558
Query: 631 DYGDI-----EIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSA 685
+ E+ + SS++ A + P L G +DD P + +
Sbjct: 559 PTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNL 618
Query: 686 PKQ--------ILQPRA--------AAAAAAAVP-------------SAGPAGPAPTSAA 716
P Q LQP+A A A+P + GPA P ++
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 717 GRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKL------------LPNG 764
T + G +S A + P + S+L E G P+
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTT--------SQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
Query: 765 DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
SPS+A T SAA P P G C Y P+ + V
Sbjct: 731 ARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYK--------PHCHQSSLSREV 782
Query: 825 LMSSPV----GRILEEERLEPQATPGPSQAASAFGAGPTQP--PHPVVPSPVRPSGGRPE 878
+ P G E +E + PG A A PT HPV V G P
Sbjct: 783 AVVMPTLARGGAAGPGEPVEVKEPPG-LPAKPPASAQPTDELLRHPVTGEVV--ERGSPM 839
Query: 879 GFL------GQRGRAVRPTRLSLEGLPSLP-SMHEYPLPPEPKSPGEYINIDFGEPGARL 931
L Q+GR+V + G SLP S+ ++ E S + F G
Sbjct: 840 ALLLAARQRAQKGRSVG----AALGRSSLPGSLRDHSHQAEASS-----DSIFHSQGTPN 890
Query: 932 SPPAPPLLASAASSSSLLSASSP---ASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKS 988
S P L A S L+ P LG GT R ++ + +P +
Sbjct: 891 SFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRH-----NWTKPEPQAPVA 945
Query: 989 PKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPAS 1048
+ APS P G L SSP P R + + PPPP + P
Sbjct: 946 WERVAPSNLPQGH---PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPE----FSNDPEP 998
Query: 1049 AVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRL 1108
Q G S S + D ++ PP + P AR A G++R
Sbjct: 999 PAPALQYLGRQS--SPPRNNYSDLRQLPNAGPGAPP-ALGFSRFPAGARYAG-AGGLERF 1054
Query: 1109 SLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSE-----------TFSSTTT 1157
S G + +PHRG + P GG R S +
Sbjct: 1055 S----GGGRSLIKKRLYVGEPHRGPGL----PHGGTGRSLSSPNCFGPQPGGPEMRRVNS 1106
Query: 1158 VTPVSPSFAHNPKRHNSASVENVSLRKSSEGG---VGVGPGGGDEPPTSPRQLQP 1209
P H P+ + + K G G P G P T+ R P
Sbjct: 1107 AGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYGSP 1161
Score = 41.6 bits (96), Expect = 0.005
Identities = 88/417 (21%), Positives = 127/417 (30%), Gaps = 83/417 (19%)
Query: 765 DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
D L P G P D PGG PL P P + P
Sbjct: 136 DLLIPPPPPGPAPGPPQDISEP---PGGSPLPSPPSTAPPPPPLLLEPPPPPS------- 185
Query: 825 LMSSPVGRILE-----EERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRP-- 877
M+ P +LE P P A PP P VP+P P+ P
Sbjct: 186 -MAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244
Query: 878 --------------EGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINID 923
+ + GR TR S P+ P PEP ++
Sbjct: 245 VGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEP-------HLT 297
Query: 924 FGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDF 983
F P + PP P+ S+ A G + + R PL ++
Sbjct: 298 F--PRSFKVPPPTPVRTSSIPVQEAQEAPRKEE-------GATKKAPSRLPLPPSFHIRP 348
Query: 984 SSP----KSPKPG--------APSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQP 1031
+S ++P+P AP+ +G A +P P P P A P P
Sbjct: 349 ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAP 408
Query: 1032 PPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPP 1091
P PP AP P A A P + + A P+P PP
Sbjct: 409 PLPPAAP------PLPCAQKAAHPPAGFTKTPKSSS------------PALKPKP--NPP 448
Query: 1092 KPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPD---PHRGAKVIRADPQGGRR 1145
PE ++P + + + + A+L S+ D HR + + G++
Sbjct: 449 SPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKK 505
>gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]
Length = 2028
Score = 69.7 bits (169), Expect = 2e-11
Identities = 205/855 (23%), Positives = 294/855 (34%), Gaps = 135/855 (15%)
Query: 305 KSQSSGSSATHPISVPG--ARRHHHLVNLPPSQTGLVRRSRTD---SLAATPPAAKCSSC 359
+S+S + A+ P ++ G +R H L P + +RR R+ ++A TP
Sbjct: 549 RSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRDALRRDRSPVRRAIAPTPGTLSGYRS 608
Query: 360 RVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALL 419
R RTA A G RP S +P +R SR+HT +L
Sbjct: 609 RARTAI-----APTPGTLRGYRPRSRRAIASTPATLRGEKSRAHT------------SLA 651
Query: 420 PAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPG---PHPPLPHPLHHG 476
PA GAL+ S A T+ S G G P PP+ +
Sbjct: 652 PAPGALRGDGSR----ARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRPPVRRAIAPT 707
Query: 477 PGQRPSSGSASASGSPSDPGFMSLDEYGSS------PGDLRAFCSHRSNTPESIAETPPA 530
PG S + PG + D G+S PG L CS RS +IA TP A
Sbjct: 708 PGALRCDRSRELTAIDPTPGALCSDRSGASRAIAPTPGTL---CSERSRVRRAIAPTPCA 764
Query: 531 RDGGGGGEFYGYM----TMDRPLSHCGRSY-----------RRVSGDAAQDLDRGLRKRT 575
G G G + R S GR+ RV A L G R
Sbjct: 765 LCGKGSQVGMGVAPTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIA--LPAGALHRD 822
Query: 576 YSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDI 635
S P R+ P P + D + T +GS P S A P P
Sbjct: 823 RS---PVRRAVAPTPGTLHCD--GSRKCTATGSTPGALPG-DRSGVSKATAPAPGALCSE 876
Query: 636 EIGSHRSSSSN---LGADDGYMPM----TPGAALAGSGSGSCRSDDYMPMSPASV----S 684
+ RS + L D ++ M TPGA L G S CR+ + ++P ++ S
Sbjct: 877 RSRARRSIAPTPCLLCGDRSWVGMGIAPTPGALLGGK-SRKCRA---IAITPGALRGGRS 932
Query: 685 APKQILQPRAAA---------AAAAAVPSA--GPAGPAPTSAAGRTFPASGGGYKASSPA 733
++++ P A A A P A G + PA TS P+ G + PA
Sbjct: 933 QKRRVVAPTPEALHGDGSWTYMAIAPTPGALHGDSSPAHTS----IIPSPGALHGDGPPA 988
Query: 734 ESS-PEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTP-PDFFSAALHPG 791
+ P G + HA + P + S A T P P
Sbjct: 989 HMAFPSTPGTLHG------DASHAHMAIAPTPGTMRGDSSTARTATAPSPGALRGDRSWK 1042
Query: 792 GEPLRGVPGCCYSS-LPRSYKAPYTCGGDSDQYVLMSSPVGRILEEE-RLEPQATPGPSQ 849
+ + PG + + RS K +V S + I+ L ++PG +
Sbjct: 1043 RKAIASTPGALHGNRSDRSRKCKAIASTPGTLHVERSPALRAIVPTPGTLGRDSSPGRTS 1102
Query: 850 AASAFGA--GPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEY 907
+ GA G P H + S + G G Q A+ PT ++ G S M
Sbjct: 1103 IIPSPGALHGDRSPAHLDIAS----TPGALHGDSSQAHTAIAPTPGTMRGDSSTARMAIA 1158
Query: 908 PLPPEPKSPGEYINIDFGE-PGA---RLSPPAPPLLASAASSSSLLSASSPASSLGSG-- 961
P + + PGA S + A A++ +LL S S
Sbjct: 1159 PSAGALRGDRSWKRKAIASTPGALRGNRSDRSRKRKAIASTPGALLGNRSDRSRKRKAIA 1218
Query: 962 -TPGT-----SSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGH------PVGSLDGLLSPE 1009
TPG S R +P + D S+ +P PG P G + S G L +
Sbjct: 1219 PTPGAPRIDRSPACRAIAPTPGALGDDSSTAIAPTPGTPRGDSSPANTAIASTPGALHGD 1278
Query: 1010 ASSPYPPLPPRP-SASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGD 1068
S + + P P SS P+PG L+ + A A PGA
Sbjct: 1279 TSQTHKAIAPTPGDLGGGSSSAHKAIAPSPGALHGDRSPAHTAIASTPGAL--------- 1329
Query: 1069 NGDYTEMAFGVAATP 1083
+GD +++ +A TP
Sbjct: 1330 HGDSSQVHTTIAPTP 1344
Score = 40.4 bits (93), Expect = 0.011
Identities = 75/336 (22%), Positives = 114/336 (33%), Gaps = 46/336 (13%)
Query: 870 VRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGA 929
+ P+ G G+ G A+ P +L G S P P + +
Sbjct: 484 IAPNPGAWRGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPGALRGYRSWTR-------- 535
Query: 930 RLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPK-- 987
R P P L+S S S AS+PA+ G + +S + L D + D S +
Sbjct: 536 RAIAPTPGTLSSYRSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRDALRRDRSPVRRA 595
Query: 988 -SPKPGAPSGHPVGSLDGLL-SPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYR-- 1043
+P PG SG+ + + +P Y P R AS ++L+ GE R
Sbjct: 596 IAPTPGTLSGYRSRARTAIAPTPGTLRGYRPRSRRAIASTPATLR--------GEKSRAH 647
Query: 1044 --LPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASP 1101
L PA G A ++ T + G+ P +P R +P
Sbjct: 648 TSLAPAPGALRGDGSRARRAIVPTTCPLCEIWSRV-GIGIAPIADALRRDRPPVRRAIAP 706
Query: 1102 TSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPV 1161
T G R +++ + DP GA + +D G R TP
Sbjct: 707 TPGALRCDRSRELTAI----------DPTPGA--LCSDRSGASR---------AIAPTPG 745
Query: 1162 SPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGG 1197
+ + R A K S+ G+GV P G
Sbjct: 746 TLCSERSRVRRAIAPTPCALCGKGSQVGMGVAPTPG 781
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 69.7 bits (169), Expect = 2e-11
Identities = 98/363 (26%), Positives = 123/363 (33%), Gaps = 70/363 (19%)
Query: 931 LSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPK 990
L PP PP A S P GS P S + PL P P
Sbjct: 138 LIPPPPPGPAPGPPQD----ISEPPG--GSPLPSPPSTAPPPPPL-------LLEPPPPP 184
Query: 991 PGAPSGHPVGSLDGLLSPEA-SSPYPPLPPR--PSASPSSSLQPPPPP-PAPGELYRLPP 1046
AP PV L+ L P SSP P PP P A P + L PPPPP PAP PP
Sbjct: 185 SMAPPPPPV--LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA-----PP 237
Query: 1047 ASAVATAQG-----PGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASP 1101
A A G PG + SD NG E AT P +P +P+ + +
Sbjct: 238 APASPHTVGTRLFPPGGVTKWKSDVALNGRQAE------ATRASPPRSPAEPKGSALGPN 291
Query: 1102 TSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPV 1161
+V PP P R + + + Q R+ T + + + P+
Sbjct: 292 PEPHLTFPRSFKVP----------PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL-PL 340
Query: 1162 SPSFAHNP-------KRHNSASVENVSLRKSSEGGVGVGPGGGDE----PPTSPRQLQPA 1210
PSF P + + + +G DE PP +P PA
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA 400
Query: 1211 PPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQP 1270
PPL P P P P + C P AGF P L P+P P
Sbjct: 401 PPLPPPAPPLPPAAPP--LPCAQKAAHP-----PAGFTK------TPKSSSPALKPKPNP 447
Query: 1271 PPP 1273
P P
Sbjct: 448 PSP 450
Score = 66.2 bits (160), Expect = 2e-10
Identities = 82/303 (27%), Positives = 107/303 (35%), Gaps = 51/303 (16%)
Query: 991 PGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPP-APGELYRLPPASA 1049
P P G G + P SP P P P L+PPPPP AP PP
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP------PPPPV 193
Query: 1050 VATAQGPGAASSLSSDTGDN--GDYTEMAFGVAATPPQPIAAPPKPEAARVAS----PTS 1103
+ P SS S T + +AF PP P APP P + P
Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG 253
Query: 1104 GVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSE---TFSSTTTVTP 1160
GV + ++G +A + PP A+P+G + E TF + V P
Sbjct: 254 GVTKWKSDVALNGRQAEATRASPPRS-------PAEPKGSALGPNPEPHLTFPRSFKVPP 306
Query: 1161 VSPSFAHNPKRHNSASVENV-SLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRP 1219
+ P R +S V+ + EG P PP+ ++PA + P P
Sbjct: 307 PT------PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSF--HIRPASQVYPDRAP 358
Query: 1220 WTPGQPGGL----VGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPL 1275
P PG L P G S + + AG P PP P PP PPL
Sbjct: 359 -EPDCPGELKATAPASPRLGQSQSQADERAG-------------TPPPAPPLP-PPAPPL 403
Query: 1276 PQP 1278
P P
Sbjct: 404 PPP 406
Score = 46.6 bits (109), Expect = 2e-04
Identities = 204/921 (22%), Positives = 308/921 (33%), Gaps = 163/921 (17%)
Query: 434 PVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPS 493
P + +PP +LS S S P PP PP P P P A A +P+
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAP--PPPPVPAPAPPAPA 240
Query: 494 DPGFMSLDEYGSSPGDLRAFCSH---RSNTPESIAETPPARDGGGGGEFYG-----YMTM 545
P + + PG + + S E+ +PP G G ++T
Sbjct: 241 SPHTVGTRLF--PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF 298
Query: 546 DRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVP-----QPSSASLDEYTL 600
R + R S Q+ RK + + P+P +P+S +
Sbjct: 299 PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPD--- 355
Query: 601 MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA 660
RA G L + PA SP++ S + G P+ P A
Sbjct: 356 -RAPEPDCPGELKATAPA-SPRLGQ-------------SQSQADERAGTPPPAPPLPPPA 400
Query: 661 ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAG----PAGPAPTSAA 716
P+ P + P P A AA P AG P +P +
Sbjct: 401 P---------------PLPPPAPPLPP--AAPPLPCAQKAAHPPAGFTKTPKSSSP-ALK 442
Query: 717 GRTFPASGGGYKASSPAE-SSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAV 775
+ P S +S+P + P +R + L + + L + V+P
Sbjct: 443 PKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE 502
Query: 776 TTGTP--PDFFSAALHPGGEPLRGVP--GCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVG 831
P P+ + P + GVP SSL + AP + S Y+ SP
Sbjct: 503 GKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAP-SLTLPSVDYIPQDSPTP 561
Query: 832 RILE-EERLEPQ-ATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVR 889
+ + LE + ++ +A + G+ P +P R GGR + + G
Sbjct: 562 SVRQIRNELEARLSSAAEKEAKPSIGSLPPKP---------RLEGGR----ICENG--AD 606
Query: 890 PTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLL 949
+LS +LP LP P + P A P PP ++L
Sbjct: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI-PPKATPEPAIPP-------KATLW 658
Query: 950 SASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPE 1009
A+ P ++LG TP + S +PL +S + P S L E
Sbjct: 659 PATPPKATLGPATP-LKATSGPTTPLKATSGPAIASTATTLPTTTS---------QLMAE 708
Query: 1010 ASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATA-----QGPGAA----- 1059
S P +P++ S+ +P E RLP A ++A PG
Sbjct: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCL 768
Query: 1060 -------SSLSSDTGDNGDYTEMAFGVAATPPQPI------AAPPKPEAARVASPTSGVK 1106
SSLS + +A G AA P +P+ P KP A+ A PT +
Sbjct: 769 YKPHCHQSSLSREVA--VVMPTLARGGAAGPGEPVEVKEPPGLPAKPPAS--AQPTDELL 824
Query: 1107 RL----SLMEQVSGVEAFLQASQPPDPHR--GAKVIRADPQGGRRRHSSETFSSTTTV-- 1158
R ++E+ S + L A Q R GA + R+ G R HS + +S+ ++
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 1159 ---TPVSPSFAHNPKRHNSASVEN-VSLRKSSEGGVGVG-PGGGDEPP-----TSPRQLQ 1208
TP SF PK A ++ ++ ++ G +G G E T P
Sbjct: 885 SQGTP--NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQA 942
Query: 1209 P------APPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEP 1262
P AP PQG P P P E F+ + P
Sbjct: 943 PVAWERVAPSNLPQGHP----LPKSFSSPPSPSNKREEEEEEFNFE--------VIPPPP 990
Query: 1263 GLPPQPQPPPPPLPQPGDKSS 1283
P+PP P L G +SS
Sbjct: 991 EFSNDPEPPAPALQYLGRQSS 1011
Score = 44.7 bits (104), Expect = 6e-04
Identities = 218/955 (22%), Positives = 297/955 (31%), Gaps = 196/955 (20%)
Query: 351 PPAAKCSSCRVRTASEG---DGGAAAGAAAAGARPVSVAGSPLSPG-PVRAPLSRSHTLS 406
P + SS V+ A E + GA A + P S P S P RAP
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAP-------E 359
Query: 407 GGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPH 466
C G A PA L S+S + A +PP A PP P P
Sbjct: 360 PDCPGELKATA--PASPRLGQSQSQADERAGTPPPA-----------------PPLPPPA 400
Query: 467 PPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAE 526
PPLP P P P A + P P + SSP L+ +PE+ A
Sbjct: 401 PPLPPPAPPLPPAAPPLPCAQKAAHP--PAGFTKTPKSSSPA-LKP--KPNPPSPENTAS 455
Query: 527 TPPA--RDGGG--------GGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRG-----L 571
+ P RD G DR LSH R A G L
Sbjct: 456 SAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH------RPGPTVAPQSKEGKKGPRL 509
Query: 572 RKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPA-SSPKVAYHPYPE 630
++ L+ PA+ P P + GS+ + P+ + P V Y P
Sbjct: 510 PEKETLLSLPAKDTPPGVPEK-----------SLGGSSLTETEAAPSLTLPSVDYIPQDS 558
Query: 631 DYGDI-----EIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSA 685
+ E+ + SS++ A + P L G +DD P + +
Sbjct: 559 PTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNL 618
Query: 686 PKQ--------ILQPRA--------AAAAAAAVP-------------SAGPAGPAPTSAA 716
P Q LQP+A A A+P + GPA P ++
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 717 GRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKL------------LPNG 764
T + G +S A + P + S+L E G P+
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTT--------SQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
Query: 765 DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
SPS+A T SAA P P G C Y P+ + V
Sbjct: 731 ARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYK--------PHCHQSSLSREV 782
Query: 825 LMSSPV----GRILEEERLEPQATPGPSQAASAFGAGPTQP--PHPVVPSPVRPSGGRPE 878
+ P G E +E + PG A A PT HPV V G P
Sbjct: 783 AVVMPTLARGGAAGPGEPVEVKEPPG-LPAKPPASAQPTDELLRHPVTGEVV--ERGSPM 839
Query: 879 GFL------GQRGRAVRPTRLSLEGLPSLP-SMHEYPLPPEPKSPGEYINIDFGEPGARL 931
L Q+GR+V + G SLP S+ ++ E S + F G
Sbjct: 840 ALLLAARQRAQKGRSVG----AALGRSSLPGSLRDHSHQAEASS-----DSIFHSQGTPN 890
Query: 932 SPPAPPLLASAASSSSLLSASSP---ASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKS 988
S P L A S L+ P LG GT R ++ + +P +
Sbjct: 891 SFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRH-----NWTKPEPQAPVA 945
Query: 989 PKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPAS 1048
+ APS P G L SSP P R + + PPPP + P
Sbjct: 946 WERVAPSNLPQGH---PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPE----FSNDPEP 998
Query: 1049 AVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRL 1108
Q G S S + D ++ PP + P AR A G++R
Sbjct: 999 PAPALQYLGRQS--SPPRNNYSDLRQLPNAGPGAPP-ALGFSRFPAGARYAG-AGGLERF 1054
Query: 1109 SLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSE-----------TFSSTTT 1157
S G + +PHRG + P GG R S +
Sbjct: 1055 S----GGGRSLIKKRLYVGEPHRGPGL----PHGGTGRSLSSPNCFGPQPGGPEMRRVNS 1106
Query: 1158 VTPVSPSFAHNPKRHNSASVENVSLRKSSEGG---VGVGPGGGDEPPTSPRQLQP 1209
P H P+ + + K G G P G P T+ R P
Sbjct: 1107 AGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYGSP 1161
Score = 41.6 bits (96), Expect = 0.005
Identities = 88/417 (21%), Positives = 127/417 (30%), Gaps = 83/417 (19%)
Query: 765 DYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYV 824
D L P G P D PGG PL P P + P
Sbjct: 136 DLLIPPPPPGPAPGPPQDISEP---PGGSPLPSPPSTAPPPPPLLLEPPPPPS------- 185
Query: 825 LMSSPVGRILE-----EERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRP-- 877
M+ P +LE P P A PP P VP+P P+ P
Sbjct: 186 -MAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244
Query: 878 --------------EGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINID 923
+ + GR TR S P+ P PEP ++
Sbjct: 245 VGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEP-------HLT 297
Query: 924 FGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDF 983
F P + PP P+ S+ A G + + R PL ++
Sbjct: 298 F--PRSFKVPPPTPVRTSSIPVQEAQEAPRKEE-------GATKKAPSRLPLPPSFHIRP 348
Query: 984 SSP----KSPKPG--------APSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQP 1031
+S ++P+P AP+ +G A +P P P P A P P
Sbjct: 349 ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAP 408
Query: 1032 PPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPP 1091
P PP AP P A A P + + A P+P PP
Sbjct: 409 PLPPAAP------PLPCAQKAAHPPAGFTKTPKSSS------------PALKPKP--NPP 448
Query: 1092 KPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPD---PHRGAKVIRADPQGGRR 1145
PE ++P + + + + A+L S+ D HR + + G++
Sbjct: 449 SPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKK 505
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 69.3 bits (168), Expect = 2e-11
Identities = 244/1071 (22%), Positives = 310/1071 (28%), Gaps = 220/1071 (20%)
Query: 367 GDGGAAAGAAAAGAR----PVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAG 422
GD G A G R G+P PGP P G G G A AG
Sbjct: 135 GDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPP---------GPPGLGGNFAAQMAG 185
Query: 423 GALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPS 482
G + + + V P P +G PGP +P PG+
Sbjct: 186 GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG--------APGPQGFQGNPGE--PGEPGV 235
Query: 483 SGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY-G 541
SG G P PG D PG R A P G G + + G
Sbjct: 236 SGPMGPRGPPGPPGKPGDDGEAGKPGK----AGERGPPGPQGARGFPGTPGLPGVKGHRG 291
Query: 542 YMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPA---RQRPVPQPSSASLDEY 598
Y +D G V G++ + G P R P + D
Sbjct: 292 YPGLDGAKGEAGAP--GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQ 349
Query: 599 TLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTP 658
G AG P PA P + P G+ R G P TP
Sbjct: 350 P-------GPAGPPGPVGPAGGP--GFPGAPGAKGEAGPTGARGPEGAQGPRGE--PGTP 398
Query: 659 GAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSA-GPAGP----APT 713
G+ SG+ +D +P + S AP A A P GP GP P
Sbjct: 399 GSPGPAGASGNPGTDG-IPGAKGSAGAP--------GIAGAPGFPGPRGPPGPQGATGPL 449
Query: 714 SAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSD 773
G+T G+K + P +G +GK G+ V P
Sbjct: 450 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ-----GAPGPAGEEGKRGARGEPGGVGPIG 504
Query: 774 AVTTGTPPDFFSAALH---PGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPV 830
PP A + PG + L G G P P GD + P
Sbjct: 505 ------PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558
Query: 831 GRILEEERLE--PQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPE----GFLGQR 884
R L + PQ GPS A G P P P G R + GF G +
Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPGEDGR----------PGPPGPQGARGQPGVMGFPGPK 608
Query: 885 GRAVRPTRLSLEGLPSLPSMHEYP----------------------------------LP 910
G P + +GLP P + P LP
Sbjct: 609 GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP 668
Query: 911 PEPKSPGEYINI-------------------DFGEPGARLSPPAPPL-----LASAASSS 946
P PGE + G PG R SP A L L +
Sbjct: 669 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 728
Query: 947 SLLSASSPASSLGS-------GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPV 999
AS PA G+ G PG + P D ++ P+ PG G
Sbjct: 729 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA-PGKDGGR-- 785
Query: 1000 GSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPA--------PGELYRLPPASAVA 1051
GL P PP P+ + + PP PA PGE P
Sbjct: 786 ----GLTGPIG-------PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 834
Query: 1052 TAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPK--------PEAARVASPTS 1103
A GP A G+ G+ + A P P AP P+ AR A
Sbjct: 835 FA-GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 893
Query: 1104 GVKRLSLMEQVSGVEAFLQASQPPDP-----HRGAKVIRADPQGGRRRHSSETFSSTTTV 1158
G G PP P G K R D G + E
Sbjct: 894 GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD--SGPPGRAGEPGLQGPAG 951
Query: 1159 TPVS--------PSFAHNPKRHNSAS----VENVSLRKSSEGGVGVGPGGGDEP-----P 1201
P PS A P + + + ++ G G+ PG EP P
Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL-PGPSGEPGKQGAP 1010
Query: 1202 TSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREE 1261
+ P P+ P G G+PG G PG+ G P R+ +AG + R E
Sbjct: 1011 GASGDRGPPGPVGPPGLTGPAGEPGR-EGSPGADGPP-GRDGAAGVKGD--------RGE 1060
Query: 1262 PGLPPQPQPPPPP-LPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGP 1311
G P P PP P P + R G +G G G GP
Sbjct: 1061 TGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP 1111
Score = 66.2 bits (160), Expect = 2e-10
Identities = 231/973 (23%), Positives = 289/973 (29%), Gaps = 208/973 (21%)
Query: 462 PPGPHPPL----PHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHR 517
PPGP P P G++ + G G P PG PG
Sbjct: 121 PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG--------- 171
Query: 518 SNTPESIAETPPARDGGGGGEFYGYM---TMDRPLSHCGRSYRRVSGDAAQDLDRGLRKR 574
P + A+ GG E G M P+ G R G A +G +
Sbjct: 172 ---PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGP--RGPPGPAGAPGPQGFQGN 226
Query: 575 TYSLTTPARQRPV-----PQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYP 629
P P+ P P D+ A G AG P P + +P
Sbjct: 227 PGEPGEPGVSGPMGPRGPPGPPGKPGDDG---EAGKPGKAGERGPPGPQGA-----RGFP 278
Query: 630 EDYGDIEIGSHRSSSSNLGAD-DGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQ 688
G + HR GA + P G + + +GS PM P + +
Sbjct: 279 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG-----PMGPRGLPGERG 333
Query: 689 ILQPRAAAAAAAAVPSAGPAG-PAPTS-AAGRTFPASGGGYKASSPAES-SPEDSGYMRM 745
P AA A GPAG P P A G FP + G + P + PE + R
Sbjct: 334 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 393
Query: 746 WCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSS 805
G+ S A P D + P + G P A PG RG PG ++
Sbjct: 394 EPGTPGSPGPAGASGNPGTDGI---PGAKGSAGAP----GIAGAPGFPGPRGPPGPQGAT 446
Query: 806 LPRSYKA----PYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGA----- 856
P K P G +Q P G E PQ PGP+ GA
Sbjct: 447 GPLGPKGQTGEPGIAGFKGEQ-----GPKG---EPGPAGPQGAPGPAGEEGKRGARGEPG 498
Query: 857 --GPTQPP----------HPVVPSPVRPSGG----RPEGFLGQRGRAVRPTRLSLEGLP- 899
GP PP P P G P G G +G P R GLP
Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558
Query: 900 --------------------SLPSMHEYPLPPEPK----SPG-------EYINIDFGEPG 928
P P PP P+ PG + N + G+ G
Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618
Query: 929 ARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKS 988
+ P AP L +A P +G G + P S + L P
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPGP---AGPAGERGEQGAPGP-SGFQGL----PGP 670
Query: 989 PKPGAPSGHP-------VGSLDGLLSPEASSPYP---------------PLPPRPSA-SP 1025
P P G P GL+ P +P LP P P
Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730
Query: 1026 SSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQ 1085
+ P PP A G PP + G A+ ++ GD GD E G P +
Sbjct: 731 KGASGPAGPPGAQG-----PP--GLQGMPGERGAAGIAGPKGDRGDVGEK--GPEGAPGK 781
Query: 1086 --------PIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIR 1137
PI PP P A G + G + PP P A
Sbjct: 782 DGGRGLTGPI-GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840
Query: 1138 ADPQGGRRRHSSET--FSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPG 1195
AD Q G + E P PS A P+ V+ K + G G PG
Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ-----GPTGVTGPKGARGAQG-PPG 894
Query: 1196 GGDEPPTSPRQLQPAPPLAPQGRPWTPGQPG-----GLVGCPGSGGSPMRRETSAGFQNG 1250
P + R P G P PG PG G G G G P R AG
Sbjct: 895 ATGFPGAAGR----VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR----AG---- 942
Query: 1251 LNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLG--------GLISAVGVGST 1302
EPGL P PP +PGD G G G++ G
Sbjct: 943 ----------EPGL-QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 991
Query: 1303 GGGCGGPGPGALP 1315
G G PGP P
Sbjct: 992 RGFPGLPGPSGEP 1004
Score = 58.2 bits (139), Expect = 5e-08
Identities = 199/856 (23%), Positives = 250/856 (29%), Gaps = 151/856 (17%)
Query: 366 EGDGGAAAGAAAAGARPVSVAGSPLSP-GPVRAPLSRSHTLSGGCGG-------RGSKVA 417
+G G A GAR P+ P G AP +R G G RG
Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538
Query: 418 LLPAGGALQHSR--SMSMPVAHS----PPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPH 471
P G R +P A P A G + S G P PPGP
Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598
Query: 472 PLHHG-PGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPA 530
P G PG + ++G +G PG L G+ A P A
Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA------GPPGPAGPAGE 652
Query: 531 RDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVP-- 588
R G G+ + P G + GD + G L P +R P
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGK--PGDQGVPGEAGAP----GLVGPRGERGFPGE 706
Query: 589 --QPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHP----YPEDYGDIEIGSHRS 642
P + L + T G+ G S PA P P P + G I +
Sbjct: 707 RGSPGAQGLQGPRGLPGT-PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765
Query: 643 SSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAV 702
++G P A G G + P PA + K + P A +A A
Sbjct: 766 DRGDVGEKG------PEGA-PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818
Query: 703 PSAGPAG----PAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADG 758
+ G G P P AG G K D+G + G
Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP--------GPQGPSG 870
Query: 759 KLLPNGDYLNVSPSDAVTTGTPPD---FFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYT 815
P G P A PP F AA G G PG P P
Sbjct: 871 APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 930
Query: 816 CGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFG-AGPTQPPHPVVPSPVRPSG 874
GDS P GR E P PG G +G PP P
Sbjct: 931 ARGDS-------GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGP---------- 973
Query: 875 GRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYP------------LPPEPKSPGEYINI 922
+G GQRG P + G P LP P PP P P +
Sbjct: 974 ---QGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP-PGLTG 1029
Query: 923 DFGEPGARLSPPA--PPLLASAASSSSLLSASSPASSLGS-GTPGTSSDSRQRSPLSDYM 979
GEPG SP A PP AA + + G+ G PG+ + D
Sbjct: 1030 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG 1089
Query: 980 NLDFSSPKSPKPGAPSGHPVGSLDGLLSP-----EASSPYP---------------PLPP 1019
P P P+G + G P EA P P PP
Sbjct: 1090 EAGAQGPMG--PSGPAG--ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1145
Query: 1020 RPS----ASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEM 1075
PS AS + P PP P A+ + GP S +TG G
Sbjct: 1146 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG----- 1200
Query: 1076 AFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKV 1135
P PP P P G+ +S + PDP +
Sbjct: 1201 --------PPGNPGPPGPP----GPPGPGI-------DMSAFAGLGPREKGPDP---LQY 1238
Query: 1136 IRAD-PQGGRRRHSSE 1150
+RAD GG R+H +E
Sbjct: 1239 MRADQAAGGLRQHDAE 1254
Score = 56.2 bits (134), Expect = 2e-07
Identities = 146/581 (25%), Positives = 178/581 (30%), Gaps = 148/581 (25%)
Query: 845 PGPSQAASAFG-----AGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLP 899
PGP G GP PP P P+ + P G G +G P +G P
Sbjct: 100 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG----PRGDRGDKGEKGAPGPRGRDGEP 155
Query: 900 SLPSMHEYPLPPEPKSP--------------------GEYINIDFGEPGARLSPPAPPLL 939
P P PP P P G + + G P + P PP
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG-PMGPMGPRGPPGP 214
Query: 940 ASAASSSSLL---------SASSPASSLG-SGTPGTSSDSRQRSPLSDYMNLDFSSPKSP 989
A A S P G G PG D + P+
Sbjct: 215 AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 274
Query: 990 K--PGAPS--------GHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPP--PPPA 1037
+ PG P G+P LDG EA +P S SP + P P P
Sbjct: 275 RGFPGTPGLPGVKGHRGYP--GLDG-AKGEAGAPG---VKGESGSPGENGSPGPMGPRGL 328
Query: 1038 PGELYRLPPASA------------------VATAQGPG-----AASSLSSDTGDNGDYTE 1074
PGE R PA A V A GPG A + TG G E
Sbjct: 329 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG--PE 386
Query: 1075 MAFGVAATPPQPIAAPPKPEAARVASPTSGV---KRLSLMEQVSGVEAFLQASQPPDPHR 1131
A G P P P P A T G+ K + ++G F PP P
Sbjct: 387 GAQGPRGEPGTP--GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444
Query: 1132 GAKVIRADPQGGRRRHSSETFSSTT----TVTPVSPSFAHNPKRHNSASVENVSLRKSSE 1187
+ P+G F P P A P A E +
Sbjct: 445 ATGPL--GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP-----AGEEGKRGARGEP 497
Query: 1188 GGVG-VGPGG-----------GDE----PPTSPRQLQPAPPLAPQGRPWTPGQPG--GLV 1229
GGVG +GP G G + P +P + P+ P+G PG+PG GL
Sbjct: 498 GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557
Query: 1230 GCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQ-----------P 1278
G G G P AG Q + G P + P PP PQ P
Sbjct: 558 GARGLTGRP----GDAGPQGKVG--------PSGAPGEDGRPGPPGPQGARGQPGVMGFP 605
Query: 1279 GDKSSWGRTRSLG--GLISAVGV----GSTG--GGCGGPGP 1311
G K + G G GL A G+ G G G G PGP
Sbjct: 606 GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646
Score = 56.2 bits (134), Expect = 2e-07
Identities = 225/981 (22%), Positives = 283/981 (28%), Gaps = 215/981 (21%)
Query: 350 TPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHT----- 404
TP + + ++G GA A A G +AG+P PGP P + T
Sbjct: 397 TPGSPGPAGASGNPGTDGIPGAKGSAGAPG-----IAGAPGFPGPRGPPGPQGATGPLGP 451
Query: 405 --------LSGGCGGRGSKVALLPAG--GALQHSRSMSMPVAHSPPAATSP-GSLSSSSG 453
++G G +G K PAG GA + A P P G
Sbjct: 452 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 511
Query: 454 HGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGS------PSDPGFMSLDEYGSSP 507
G+ +P G P PG+R SG A G+ P +PG P
Sbjct: 512 PGNRGFPGQDGLAGP-----KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 566
Query: 508 GDL--RAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQ 565
GD + E PP G G G M P + +G+ +
Sbjct: 567 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQP--GVMGFPGP--------KGANGEPGK 616
Query: 566 DLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAY 625
++GL P + +G+AG P+ PA
Sbjct: 617 AGEKGLPGAPGLRGLPGKDGE-------------------TGAAGPPGPAGPAGERGEQG 657
Query: 626 HPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAG-------------SGSGSCRS 672
P P + + D G L G G+ +
Sbjct: 658 APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 717
Query: 673 DDYMPMSPASVSAPKQILQPRAAAAAAAAVPSA-GPAG----PAPTSAAGRTFPASGGGY 727
+P +P + PK A+ A P A GP G P AAG P G
Sbjct: 718 PRGLPGTPGT-DGPK-------GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769
Query: 728 KASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAA 787
E +P G G L+ G + P G V P A
Sbjct: 770 VGEKGPEGAPGKDG------GRGLT-----GPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818
Query: 788 LHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGP 847
PG G PG P + P G G E + PGP
Sbjct: 819 GAPGERGETGPPG------PAGFAGPPGADG-------QPGAKGEQGEAGQKGDAGAPGP 865
Query: 848 SQAASAFGAGPTQPPHPVVPSPVRPSGGRP--EGFLGQRGRAVRPTRLSLEGLPSLPSMH 905
+ A GP P P R + G P GF G GR V P P +
Sbjct: 866 QGPSGA--PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGR-VGP-----------PGSN 911
Query: 906 EYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGT 965
P PP P P G GAR PP A L + P G PG
Sbjct: 912 GNPGPPGPPGPSG----KDGPKGAR-GDSGPP---GRAGEPGLQGPAGPPGE--KGEPGD 961
Query: 966 SSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASP 1025
S P P P +G + GL +P L P PS P
Sbjct: 962 DGPSGAEGP--------------PGPQGLAGQ--RGIVGLPGQRGERGFPGL-PGPSGEP 1004
Query: 1026 SSSLQP-------PPPPPAPGELYRLPPASAVATAQGPGAASSLSSD--TGDNGDYTEMA 1076
P PP P P L PA PGA D G GD E
Sbjct: 1005 GKQGAPGASGDRGPPGPVGPPGL--TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGET- 1061
Query: 1077 FGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVI 1136
G P AP P + A PT +Q EA Q P GA+ I
Sbjct: 1062 -GAVGAP----GAPGPPGSPGPAGPTG--------KQGDRGEAGAQGPMGPSGPAGARGI 1108
Query: 1137 RADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGV-GPG 1195
+ PQG R P ++ + G G GP
Sbjct: 1109 QG-PQGPRGDKGEAG----------EPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA 1157
Query: 1196 GGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIA 1255
G P+ PR P P+ P G+ G PG +G PG P R G
Sbjct: 1158 G----PSGPR--GPPGPVGPSGKDGANGIPGP-IGPPG----PRGRSGETG--------- 1197
Query: 1256 IDVREEPGLPPQPQPPPPPLP 1276
PG P P PP PP P
Sbjct: 1198 --PAGPPGNPGPPGPPGPPGP 1216
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,253,202
Number of Sequences: 37866
Number of extensions: 5347889
Number of successful extensions: 80541
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 623
Number of HSP's successfully gapped in prelim test: 2502
Number of HSP's that attempted gapping in prelim test: 30700
Number of HSP's gapped (non-prelim): 33988
length of query: 1338
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1224
effective length of database: 13,930,794
effective search space: 17051291856
effective search space used: 17051291856
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.