Guide to the Human Genome
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Search of human proteins with 38570073

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo
sapiens]
         (642 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens]     1370   0.0  
gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]     1318   0.0  
gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens]      433   e-121
gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]      432   e-121
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      431   e-120
gi|22027599 alpha 1 type XIII collagen isoform 14 [Homo sapiens]      429   e-120
gi|22027591 alpha 1 type XIII collagen isoform 10 [Homo sapiens]      429   e-120
gi|22027577 alpha 1 type XIII collagen isoform 5 [Homo sapiens]       427   e-119
gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]     427   e-119
gi|22027593 alpha 1 type XIII collagen isoform 11 [Homo sapiens]      427   e-119
gi|22027574 alpha 1 type XIII collagen isoform 4 [Homo sapiens]       426   e-119
gi|22027571 alpha 1 type XIII collagen isoform 3 [Homo sapiens]       424   e-118
gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens]      422   e-118
gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]      421   e-118
gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens]      417   e-116
gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens]       416   e-116
gi|22027589 alpha 1 type XIII collagen isoform 9 [Homo sapiens]       415   e-116
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     415   e-116
gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens]       412   e-115
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    412   e-115
gi|22027565 alpha 1 type XIII collagen isoform 1 [Homo sapiens]       412   e-115
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   409   e-114
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   409   e-114
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   409   e-114
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     409   e-114
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   408   e-114
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   408   e-114
gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens]       406   e-113
gi|22027595 alpha 1 type XIII collagen isoform 12 [Homo sapiens]      405   e-113
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   405   e-113

>gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens]
          Length = 642

 Score = 1370 bits (3545), Expect = 0.0
 Identities = 642/642 (100%), Positives = 642/642 (100%)

Query: 1   MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQ 60
           MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQ
Sbjct: 1   MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQ 60

Query: 61  ARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNC 120
           ARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNC
Sbjct: 61  ARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNC 120

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
           PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ
Sbjct: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180

Query: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240
           LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG
Sbjct: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240

Query: 241 PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG 300
           PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG
Sbjct: 241 PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG 300

Query: 301 EKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT 360
           EKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT
Sbjct: 301 EKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT 360

Query: 361 KGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQK 420
           KGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQK
Sbjct: 361 KGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQK 420

Query: 421 GDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGL 480
           GDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGL
Sbjct: 421 GDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGL 480

Query: 481 KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPP 540
           KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPP
Sbjct: 481 KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPP 540

Query: 541 GPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP 600
           GPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP
Sbjct: 541 GPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP 600

Query: 601 GPRGEKGDLGEKGEKVTSPSQHVPCLILLLLSALLFSLCDSI 642
           GPRGEKGDLGEKGEKVTSPSQHVPCLILLLLSALLFSLCDSI
Sbjct: 601 GPRGEKGDLGEKGEKVTSPSQHVPCLILLLLSALLFSLCDSI 642


>gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]
          Length = 654

 Score = 1318 bits (3411), Expect = 0.0
 Identities = 615/615 (100%), Positives = 615/615 (100%)

Query: 1   MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQ 60
           MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQ
Sbjct: 1   MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQ 60

Query: 61  ARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNC 120
           ARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNC
Sbjct: 61  ARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNC 120

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
           PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ
Sbjct: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180

Query: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240
           LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG
Sbjct: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240

Query: 241 PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG 300
           PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG
Sbjct: 241 PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG 300

Query: 301 EKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT 360
           EKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT
Sbjct: 301 EKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT 360

Query: 361 KGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQK 420
           KGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQK
Sbjct: 361 KGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQK 420

Query: 421 GDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGL 480
           GDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGL
Sbjct: 421 GDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGL 480

Query: 481 KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPP 540
           KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPP
Sbjct: 481 KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPP 540

Query: 541 GPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP 600
           GPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP
Sbjct: 541 GPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP 600

Query: 601 GPRGEKGDLGEKGEK 615
           GPRGEKGDLGEKGEK
Sbjct: 601 GPRGEKGDLGEKGEK 615



 Score =  167 bits (424), Expect = 2e-41
 Identities = 92/204 (45%), Positives = 109/204 (53%), Gaps = 8/204 (3%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
           P GPPG +G +G +GE G PG PG  G  G KG KG+ GD G  M   K   G       
Sbjct: 450 PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPG--MTGEKGGIGLPG---- 503

Query: 181 LIKRRLIKGDQGQAGPPGPPGPP--GPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGP 238
           L     +KG++G +G PGP GP   GP GPPG  G  GP G  G+PG  G  G  G  GP
Sbjct: 504 LPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGP 563

Query: 239 LGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGD 298
            GP G++G  GA G PG  G  G PG  G  G +G PGP+GE G+ GEKG+ G  G KG+
Sbjct: 564 AGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGE 623

Query: 299 TGEKGDPGSSAAGIKGEPGESGRP 322
            GE G PG        + G  G P
Sbjct: 624 KGEPGQPGLDGLDAPCQLGPDGLP 647


>gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens]
          Length = 668

 Score =  433 bits (1113), Expect = e-121
 Identities = 273/669 (40%), Positives = 328/669 (49%), Gaps = 123/669 (18%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++                            GP GPPG PG RG
Sbjct: 138 AIGMPGRVGSPGDAGLSII----------------------------GPRGPPGQPGTRG 169

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPG--------------- 252
            PG  G   P G+ G PG PG  G+ GL GP G PG +G  G  G               
Sbjct: 170 FPGFPG---PIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMP 226

Query: 253 -------IPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDP 305
                  I  + G++ +  + G  G  G PGP G  G  G  G  G  G  G  G KGDP
Sbjct: 227 AALRSSQIIALKGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDP 286

Query: 306 GSSAAGIKGEPGESGRPGQKGEPGLPGLPGLP--GIKGEPGFIGPQGE------PGLPGL 357
           G    G  G  GE G PG  G+ G  G PG+   G+KGEPG  G +GE      PGLPGL
Sbjct: 287 GIQ--GYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGL 344

Query: 358 PGTKGERGEAGPP---GRGERGEPGAPGPKGKQGESGTRG---PKGSKGDRGEKGDSGAQ 411
            G KGE+G+AG     GRGE G PG PGP G +GE+G  G   P G  GD+GE+G +G Q
Sbjct: 345 LGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQ 404

Query: 412 GPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPP------GPPGPQGLQGPKGE 465
           GP GP G KG+ G  E++DYNGN++EALQ I TL + GPP      GPPG  G+ G KGE
Sbjct: 405 GPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGE 464

Query: 466 QGSPGIPGMDGEQGLKGSKGDMGDPGMTGE---------KGGIGLPGLPGANGMKGEKGD 516
            G PG PG DGE+G +G  GDMG PG  G          KG  G PG PG  G KGE G 
Sbjct: 465 IGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQ 524

Query: 517 SGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPK------------------GTDGPM 558
           +G P P  P   GPPGPPG  G PGP G  GL G K                  GT GP+
Sbjct: 525 AGSPVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPI 584

Query: 559 GPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--V 616
           G  GPAGPKGERG KG  G  GP G  GLPG  G PG  G  G RG+KG  G KG+K   
Sbjct: 585 GVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQ 644

Query: 617 TSPSQHVPC 625
            +P    PC
Sbjct: 645 GAPGLDAPC 653



 Score =  160 bits (405), Expect = 3e-39
 Identities = 91/206 (44%), Positives = 110/206 (53%), Gaps = 26/206 (12%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
           GPPG  G++G RG+ G  G PGPQGPPG  G  G +G+ G         H     ++   
Sbjct: 469 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENG---------HPGSPGEKGE- 518

Query: 183 KRRLIKGDQGQAGPP-----GPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMG 237
                KG+ GQAG P     GP GPPGP G  G  G  G  G+ G  GE G  GE+G  G
Sbjct: 519 -----KGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRG 573

Query: 238 PLGPPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP---GPKGEPGEQGEKGDAG 291
           PLG PG  G IG PG  G  G+   KG+PG+ G  G  G+P   GP G+ G +GE+G  G
Sbjct: 574 PLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKG 633

Query: 292 ENGPKGDTGEKGDPGSSAAGIKGEPG 317
             GPKGD G++G PG  A    GE G
Sbjct: 634 SRGPKGDKGDQGAPGLDAPCPLGEDG 659



 Score =  157 bits (397), Expect = 3e-38
 Identities = 109/281 (38%), Positives = 124/281 (44%), Gaps = 59/281 (20%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ  
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQ-- 164

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
                                        PG  G  G  GP G  G PG PG  G+ GL 
Sbjct: 165 -----------------------------PGTRGFPGFPGPIGLDGKPGHPGPKGDMGLT 195

Query: 482 GSKGDMGDPGMTGEKGGIG-------LPGLPGAN------GMKGEKGDSGMPGPQGPSII 528
           G  G  G  G  GEKG  G       L  +P A        +KGE+  +        SI 
Sbjct: 196 GPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQSQA--------SIQ 247

Query: 529 GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLP 588
           GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G+P
Sbjct: 248 GPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPGMP 304

Query: 589 GKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           GK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 305 GKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 345


>gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]
          Length = 655

 Score =  432 bits (1111), Expect = e-121
 Identities = 278/673 (41%), Positives = 330/673 (49%), Gaps = 144/673 (21%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRR--GESGPPGQPGP 145
            +  +V +LL +K   H  + R A +    CNCP  P G  G  G    G  GPPGQPG 
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCPPAPQGSPGDAGLSIIGPRGPPGQPGT 146

Query: 146 QGPPG---PKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGP 202
           +G PG   P G  G+ G  GP                        KGD G  GPPG PGP
Sbjct: 147 RGFPGFPGPIGLDGKPGHPGP------------------------KGDMGLTGPPGQPGP 182

Query: 203 PGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGE 262
            G +G  G  G+   RG      E  +   QG  GP GPPG  G +G PG+PG     G 
Sbjct: 183 QGQKGEKGQCGEYPHRG------EQSQASIQGPPGPPGPPGPSGPLGHPGLPG---PMGP 233

Query: 263 PGLPGAVGQNGIPGPKGEPGEQG---EKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGES 319
           PGLPG       PGPKG+PG QG    KG+ G  G  G  G KG PG + AG+KGEPG  
Sbjct: 234 PGLPGP------PGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIP 287

Query: 320 GRPGQKGEPGLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGE 374
           G  G+KG  G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+
Sbjct: 288 GTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQ 345

Query: 375 RGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGN 434
            G PG PG KG++G +G +GP G KG +GE G             KG     E++DYNGN
Sbjct: 346 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGN 387

Query: 435 LHEALQRITTLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMG 488
           ++EALQ I TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG
Sbjct: 388 INEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMG 447

Query: 489 DPGMTGE---------KGGIGLPGLPGANGMKGEKGDSGMPGPQG--------------- 524
            PG  G          KG  G PG PG  G KGE G +G PG +G               
Sbjct: 448 PPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGL 507

Query: 525 PSIIGPPGPPGPHGPPGPMGPHGL------------------------------PGPKGT 554
           P   GPPGPPG  G PGP G  GL                              PGP GT
Sbjct: 508 PGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGT 567

Query: 555 DGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
            GP+G  GPAGPKGERG KG  G  GP G  GLPG  G PG  G  G RG+KG  G KG+
Sbjct: 568 PGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGD 627

Query: 615 K--VTSPSQHVPC 625
           K    +P    PC
Sbjct: 628 KGDQGAPGLDAPC 640



 Score =  156 bits (395), Expect = 5e-38
 Identities = 96/225 (42%), Positives = 114/225 (50%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 429 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 488

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 489 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 541

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGM---------------NGQKGEPGLPGAVGQNGIP 275
           GE+G  GPLG PG  G  G PG PG                 G KG+PG+ G  G  G+P
Sbjct: 542 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 601

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 602 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 646



 Score =  154 bits (390), Expect = 2e-37
 Identities = 94/215 (43%), Positives = 109/215 (50%), Gaps = 17/215 (7%)

Query: 427 EIIDYNGNLHEALQRITTLTVTGPPGPPGPQG--------LQGPKGEQGSPGIPGMDGEQ 478
           +++D    LH   +R    T  G   PP PQG        + GP+G  G PG  G  G  
Sbjct: 94  QLLDEKWKLHSRRRREAPKTSPGCNCPPAPQGSPGDAGLSIIGPRGPPGQPGTRGFPGFP 153

Query: 479 GLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGP----SIIGPPGPP 534
           G  G  G  G PG  G+ G  G PG PG  G KGEKG  G    +G     SI GPPGPP
Sbjct: 154 GPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRGEQSQASIQGPPGPP 213

Query: 535 GPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEP 594
           GP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G+PGK G  
Sbjct: 214 GPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK 270

Query: 595 GLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 271 GAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 305


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  431 bits (1107), Expect = e-120
 Identities = 259/593 (43%), Positives = 304/593 (51%), Gaps = 92/593 (15%)

Query: 110  IAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPK---------GDKGEQGD 160
            +  + P     P GP GK G+RGR G  G  G PG  GP G +         G+KG +GD
Sbjct: 588  VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647

Query: 161  QGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKD----- 215
             GP              D   +  R + G+ G  G  GP GPPGP GPPG TG D     
Sbjct: 648  PGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGP 707

Query: 216  ----GPRGMPGVPGEPGKPGEQGLMGP---LGPPGQKGSIGAPGIPGMNGQKGEPGLPGA 268
                GP+G PG PG+ G PG QGL GP   +GPPG+KG +G PG+PGM G  G PG PG 
Sbjct: 708  KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK 767

Query: 269  VGQ------NGIPGPKGE---PGEQGEKGDAGENGPKGDTGEKGDPG----SSAAGIKGE 315
             G        G PGP+G    PG +G KG  G  G KG  GEKG+ G        GIKG+
Sbjct: 768  EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 827

Query: 316  PGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGE------PGLPGLPGTKGERGEAGP 369
             GE G PG +GE G  G  G  G  G+PG +GP GE      PGLPG PG +G +G  G 
Sbjct: 828  RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887

Query: 370  PG-------RGERGEPGAPGPKGKQGES---GTRGPKGSKGDRGEKGDSGAQGPRGPPGQ 419
            PG       +G RG PG PGP+G++G +   G RGP+G  G  G KG+SG  GP GPPG+
Sbjct: 888  PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 947

Query: 420  KGDQGATEIIDYNGNL-------------HEALQRITTLT-VTGPPGPP------GPQGL 459
            +G  G      + G               H   +  T     TGPPGPP      GP G 
Sbjct: 948  RGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE 1007

Query: 460  QGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGM 519
             GP GE+G PG PG  GEQGL G     G  G  G+ G  GLPG  G  G++G  GD G+
Sbjct: 1008 TGPMGERGHPGPPGPPGEQGLPGL---AGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGL 1064

Query: 520  PGPQGPSII----GPPGPPGPHGPPGPMGPHGLPGP---KGTDGPMGPHGPAGPKGERGE 572
            PGP G   +    GPPGPPGP G PG  GP G  GP    G  GP GP GPAG KG  GE
Sbjct: 1065 PGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGE 1124

Query: 573  KGAMGE------------PGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
            KG  G             PGP GP G PG+DG+ G  G PG +G KGD GE+G
Sbjct: 1125 KGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQG 1177



 Score =  415 bits (1067), Expect = e-116
 Identities = 253/540 (46%), Positives = 285/540 (52%), Gaps = 54/540 (10%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVF-PKINHGFLSADQ 179
            P G PGK G  G +G  GPPG  GP G PGP+G KG  G +G +     K   GF     
Sbjct: 761  PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820

Query: 180  QLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPL 239
             +     IKGD+G+ GPPGP G  GP GP G  G +G  G  G PGE GK G  GL G  
Sbjct: 821  DMG----IKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYP 876

Query: 240  GPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDT 299
            G  G KGSIG PG PG NG+KG  G PG  G  G  GP G  GE+G +G  G+ GPKG++
Sbjct: 877  GRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNS 936

Query: 300  GEKGDPG-SSAAGIKGEPGESGRPGQKGEPGLP---GLPGLPGIKGEPGFIGPQGEPGLP 355
            G  G  G     G  G  G +G PG KG PG P   GLPG PG +GE GF G  G PG P
Sbjct: 937  GGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPP 996

Query: 356  GLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGP-- 413
            G+ G +G  GE GP   GERG PG PGP G+QG  G  G +G+KGD G  G  G  GP  
Sbjct: 997  GVVGPQGPTGETGP--MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPG 1054

Query: 414  -RGPPGQKGDQGATEIIDYNGNLHE-----------------ALQRITTLTVTGPPGPPG 455
             RG PG +G  G    +   GN                    A   I      GP GPPG
Sbjct: 1055 LRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPG 1114

Query: 456  PQGLQGPKGEQGSPGIPGMDGEQ---GLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG 512
            P G +G  GE+G  G  G DG Q   GL G  G +G PG  G+KG IG PG  G+ G KG
Sbjct: 1115 PAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKG 1174

Query: 513  EKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGP------ 566
            E+G  G  GPQGP  IG PGP G  G PGP G  GL G KG +GP G  GP GP      
Sbjct: 1175 EQGPPGPTGPQGP--IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232

Query: 567  ------KGERGEKGAM---GEPGPRGPYGLPGKD---GEPGLDGFPGPRGEKGDLGEKGE 614
                  KGE G+ G M   G PGPRGP G PG D   G PG  G PG  GEKG+ GE GE
Sbjct: 1233 PGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGE 1292



 Score =  413 bits (1061), Expect = e-115
 Identities = 242/542 (44%), Positives = 280/542 (51%), Gaps = 60/542 (11%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKIN----HGFLS 176
            P GP G+ G  G RG  GPPG PG QG PG  G +G +GD GP  +  K       GF  
Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF-P 1059

Query: 177  ADQQL---IKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTG------KDGPRGMPGVPGEP 227
             D+ L   +    +KG++G  GPPGP G PG RGP G  G      + GP+G PG  GE 
Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEK 1119

Query: 228  GKPGEQGLMGPLGPPGQKGSIGAPGI------PGMNGQKGEPGLPGAVGQNGIPGPKGEP 281
            G PGE+G  GP G  G +G +G PG       PG +G KGE G PG  G  G  G +G P
Sbjct: 1120 GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPP 1179

Query: 282  GEQGEKGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPGLPGLPGIK 340
            G  G +G  G+ GP G  GE G  G     G KG+ G  G PG  G  GL GLPG PG K
Sbjct: 1180 GPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEK 1239

Query: 341  GEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR----------GERGEPGAPGPKGKQGES 390
            GE G +G  G PG PG  G  G  G  GP G           GE+GEPG  G  G  GE 
Sbjct: 1240 GETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299

Query: 391  GTRGPKGSKGDRGEKGDSGAQGP---RGPPGQKGDQGATEIIDYNGNLHEALQRITTLTV 447
            G  GPKG +G++GE G SGA GP   +GPPG  G +G+   + + G+             
Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD------------- 1346

Query: 448  TGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGA 507
             GPPG PGP G  GP G++G  G PG  G  G  G  G  G PG  G  G  G  G  G 
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGE 1406

Query: 508  NGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGP------PGPMGPHGLPG---PKGTDGPM 558
             G KGE G  G PG  GP  IGP G PG  GP      PGP+G  GLPG   P G  GPM
Sbjct: 1407 KGAKGEAGLEGPPGKTGP--IGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPM 1464

Query: 559  GPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTS 618
            GP G  G KG+ G KG  G PG  G  G PG+ GE G  G PGP+G  G  GE+G  +T 
Sbjct: 1465 GPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQG--ITG 1522

Query: 619  PS 620
            PS
Sbjct: 1523 PS 1524



 Score =  404 bits (1039), Expect = e-112
 Identities = 251/564 (44%), Positives = 284/564 (50%), Gaps = 91/564 (16%)

Query: 121  PAGPPGKRGKRGRRGESG------PPGQPGPQGPPGPKGDKGEQGDQG-------PRMVF 167
            PAGPPG+RG  G +G +G      PPG PG  G PG  G +GE G QG       P +V 
Sbjct: 941  PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000

Query: 168  PKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEP 227
            P+   G               G  G+ G PGPPGPPG +G PG  GK+G +G PG  G P
Sbjct: 1001 PQGPTGET-------------GPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047

Query: 228  GK---------PGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPG-- 276
            GK         PG++GL GP+G  G KG+ G PG PG  G  GE G  GA G  GIPG  
Sbjct: 1048 GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107

Query: 277  -PKGEPGEQGEKGDAGENGPKGDTGEKGDPGS----SAAGIKGEPGESGRPGQKGEPGLP 331
             P+G PG  GEKG  GE GP+G  G  G  G       AG  G PGE G  G+ GEPG  
Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQK 1167

Query: 332  GLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGE------------------RGEAGPPGR- 372
            G  G  G +G PG  GPQG  G PG  G  GE                  RG  GPPG  
Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPV 1227

Query: 373  GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYN 432
            G +G PG PG KG+ G+ G  GP G  G RG  G  GA GP+GPPG  G+ GA   +   
Sbjct: 1228 GLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGA---VGEK 1284

Query: 433  GNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGI---------PGMDGEQGLKGS 483
            G   EA +      + G  GPPGP+G +G KGE G  G          PG DG +G  G 
Sbjct: 1285 GEPGEAGEP----GLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP 1340

Query: 484  KGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPM 543
             G  GDPG  GE G  G  G PG  G  GE G +G PGP G    GP GPPG  GPPGP 
Sbjct: 1341 VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEP--GPSGPPGKRGPPGPA 1398

Query: 544  GPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPR 603
            GP G  G KG  G  G  GP G  G  G +GA G+PGP G  G+PG  GE GL G PGP 
Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPD 1458

Query: 604  GE------------KGDLGEKGEK 615
            G             KGD G KGEK
Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEK 1482



 Score =  403 bits (1036), Expect = e-112
 Identities = 242/535 (45%), Positives = 276/535 (51%), Gaps = 89/535 (16%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E P     PAG PG+RG  G  G  G PG+PGPQGPPGP G+KG  G++GP+   P    
Sbjct: 1077 EGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG--PAGRD 1134

Query: 173  GFLS-----------------ADQQLIK---RRLIKGDQGQAGPPGPPGPPGPRGPPGDT 212
            G                     D+  I    ++  KGD+G+ GPPGP GP GP G PG +
Sbjct: 1135 GLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPS 1194

Query: 213  GKDG------------------PRGMPGVPGE------PGKPGEQG------LMGPLGPP 242
            G DG                  PRG PG PG       PG PGE+G       MGP GPP
Sbjct: 1195 GADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPP 1254

Query: 243  GQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEK 302
            G +G  GAPG  G  G  G  G PGAVG+ G PG  GEPG  GE    G  GPKG+ GEK
Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE---GGPPGPKGERGEK 1311

Query: 303  GDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKG 362
            G+ G S  G  G PG  G PG  G  G PG  G PG  G PG  GP G+ G PG  G  G
Sbjct: 1312 GESGPS--GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDG 1369

Query: 363  ERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGD 422
            E G+ G P  G  GEPG  GP GK+G  G  GP+G +G++G KG++G +GP G  G  G 
Sbjct: 1370 EPGQTGSP--GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGP 1427

Query: 423  QGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMD---GEQG 479
            QGA                       G PGP G +G+ GP GEQG PG PG D   G  G
Sbjct: 1428 QGA----------------------PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMG 1465

Query: 480  LKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGP 539
              G  G  GD G  GEKG  GL GL G  G +GEKGD G+PGPQG S  GP G  G  GP
Sbjct: 1466 PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS--GPKGEQGITGP 1523

Query: 540  PGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEP 594
             GP+GP   PGP G  GP GP G  G  G  G KG  G PGP GP G PG+  +P
Sbjct: 1524 SGPIGP---PGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQP 1575



 Score =  399 bits (1024), Expect = e-111
 Identities = 251/605 (41%), Positives = 294/605 (48%), Gaps = 129/605 (21%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDK----------GEQGDQGPRMVFPKINH 172
            GP G+ G  G RG  G PG PG  G PGP G            G+ G +GP MV  + + 
Sbjct: 487  GPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGP-MVSAQESQ 545

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGP---RGPPGDTGKDGPRGMPGVPGEPGK 229
                  Q  +  R   G  G  G PGP GPPG    +G PGD G  GPRG+ G PG  GK
Sbjct: 546  AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGK 605

Query: 230  PGE---------QGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGE 280
            PG          +G+ G  GP G +G  G  G+PG  G +G+PG  G  G  G  G +G+
Sbjct: 606  PGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGD 665

Query: 281  PGEQGEKGDAGENGPKGDTGEKGDPG----SSAAGIKGEP---------GESGRPGQKGE 327
             GE G +G  GE GP+G  G KG PG        G+ G+P         GE G PGQ+G 
Sbjct: 666  DGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGN 725

Query: 328  PGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT---KGERGEAGPPG-RGERGEPGA--- 380
            PG  GLPG  G  G PG  GP G+PGLPG+PG     G  G+ GPPG +G +G PG    
Sbjct: 726  PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGP 785

Query: 381  ---PGPKGKQGESGTRGPKGSKGDRGE------KGDSGAQGPR---GPPGQKGDQGATEI 428
               PGP+G +G  G RG KG+KG++GE      KGD G +G R   GPPG +G+ G  E 
Sbjct: 786  IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDG-PEG 844

Query: 429  IDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMG 488
                G               GP G PGP G  G KG+ G PG+PG  G QG KGS G  G
Sbjct: 845  PKGRG---------------GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPG 889

Query: 489  DPGMTGEKGGIGLPGLPGANGM---------KGEKGDSGMPGPQGPS-IIGPPGPPGPHG 538
             PG  GEKGG G PG PG  G          +G +G +G PGP+G S   GP GPPG  G
Sbjct: 890  FPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERG 949

Query: 539  PPGPMGPHGLPGPKGTDGP------------------------------MGPHGPAGPKG 568
            P GP GP G PGPKG  GP                              +GP GP G  G
Sbjct: 950  PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009

Query: 569  ERGEKGAMGEPGP------------------RGPYGLPGKDGEPGLDGFPGPRGEKGDLG 610
              GE+G  G PGP                   GP GLPGKDG PGL GFPG RG  G +G
Sbjct: 1010 PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1069

Query: 611  EKGEK 615
              G K
Sbjct: 1070 ALGLK 1074



 Score =  396 bits (1018), Expect = e-110
 Identities = 240/546 (43%), Positives = 276/546 (50%), Gaps = 72/546 (13%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG-PRMVFPKINHGFLSADQQL 181
            G PG+RG+ G +G++GPPG PG  GP GP G+ G  G++G P    P    G       L
Sbjct: 976  GHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPG----L 1031

Query: 182  IKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGP---------RGMPGVPGEPGKPGE 232
              +   KGD G AG PG  GPPG RG PGD G  GP          G PG PG  G PGE
Sbjct: 1032 AGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGE 1091

Query: 233  QGLMG------------PLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGE 280
            +G  G            P GPPG  G  GAPG  G  G  G  GL G VG  G  GP G 
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP 1151

Query: 281  PGEQGEKGDAGE---NGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPGLPGL 336
            PGE G+KG+ GE    G KGD GE+G PG +   G  G+PG SG  G+ G  G  GL G 
Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQ 1211

Query: 337  PGIKGEPGFIGPQGEPGLPGLPGTKGERGEAG---------PPG-RGERGEPGAPGPKGK 386
             G +G  GF GP G  GL GLPG  GE+GE G         PPG RG  G PGA GP+G 
Sbjct: 1212 KGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP 1271

Query: 387  QGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLT 446
             G  G  G  G KG+ GE G+ G  G  GPPG KG++G       +G             
Sbjct: 1272 PGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSG------------- 1318

Query: 447  VTGPPGPPGPQGLQGPKG---------EQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKG 497
              GPPGP GP G  GPKG         + G PG PG  G+ G  G KGD G+PG TG  G
Sbjct: 1319 AAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG 1378

Query: 498  GIGLPGLPGANGMKGEKGDSGMPGPQGPS-IIGPPGPPGPHGPPGPMGPHGLPGPKGTDG 556
              G PG  G  G +G  G +G  G QG     G  G  GP G  GP+GP G PG  G DG
Sbjct: 1379 PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG 1438

Query: 557  PMGPHGPAGPKGERGEKGAMGEPGPRGPYGLP---------GKDGEPGLDGFPGPRGEKG 607
              G  GP G +G  G  G  G PGP GP GLP         G+ G PGL G  GP GE+G
Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQG 1498

Query: 608  DLGEKG 613
            + G++G
Sbjct: 1499 EKGDRG 1504



 Score =  260 bits (665), Expect = 2e-69
 Identities = 172/437 (39%), Positives = 202/437 (46%), Gaps = 68/437 (15%)

Query: 196 PPGPPGPPGPRGPPG-DT---GKDGPRGMPGVPGEPG--KPGEQGLMGPLGPPGQKGSIG 249
           P   P   GP  P   DT   G  GPRG  G  GEP   +PG    M   GPPG +G  G
Sbjct: 423 PTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPG----MLIEGPPGPEGPAG 478

Query: 250 APGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDT-------GEK 302
            PG          PG  G  GQ G PG +G PG  G  G  G  GP G         G  
Sbjct: 479 LPG---------PPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGG 529

Query: 303 GDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKG 362
           GD GS    +  +  ++    Q+    L G  G  G+ G PG +GP      PG  G KG
Sbjct: 530 GDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGP------PGSGGLKG 583

Query: 363 ERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKG 421
           E G+ GP G RG +G PG  G  G++G +G+ G +G  G  G KGD G  G  G PG+KG
Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
            +G                        GP GPPGP G  G +G+ G  G  G+ GE G +
Sbjct: 644 HRGDP----------------------GPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR 681

Query: 482 GSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHGPP 540
           G  G  G PG  G  G  G+ G PG  G  G +G+ G PG QG P   G PGP G  GPP
Sbjct: 682 GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPP 741

Query: 541 GPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP 600
           G  GP G PG  G  G  GP G  G +G  GEKG  G PGP+GP G            +P
Sbjct: 742 GEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIG------------YP 789

Query: 601 GPRGEKGDLGEKGEKVT 617
           GPRG KG  G +G K T
Sbjct: 790 GPRGVKGADGIRGLKGT 806



 Score =  129 bits (325), Expect = 6e-30
 Identities = 78/184 (42%), Positives = 85/184 (46%), Gaps = 18/184 (9%)

Query: 103  EHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG 162
            E  AK     E P     P GP G  GK G  G  G PG  G QG PG  G  G  G  G
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMG 1465

Query: 163  PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPG 222
            P    P +                +KGD G  G  G PG  G  GPPG+ G+ G RG+PG
Sbjct: 1466 P----PGLPG--------------LKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1507

Query: 223  VPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPG 282
              G  G  GEQG+ GP GP G  G  G PG PG  G KG  G  G  G+ G PGP G PG
Sbjct: 1508 PQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPG 1567

Query: 283  EQGE 286
              GE
Sbjct: 1568 PPGE 1571



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 83/251 (33%), Positives = 104/251 (41%), Gaps = 47/251 (18%)

Query: 408 SGAQGPRGPPGQKGDQGATE-----IIDYNGNLHEALQRITTLTVTGPPGPPGPQ----- 457
           S +  P  PPG+  D    E     I + + N ++     T+      PG P  Q     
Sbjct: 384 SNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYE 443

Query: 458 GLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDS 517
           G+ GP+GE+G  G P +  E G       M   G  G +G  GLPG PG  G  G+ GD 
Sbjct: 444 GIGGPRGEKGQKGEPAII-EPG-------MLIEGPPGPEGPAGLPGPPGTMGPTGQVGD- 494

Query: 518 GMPGPQGPSIIGPPGPPGPHGPPGPMGP-------HGLPGPKGTDGPM------------ 558
             PG +GP   G PG PG  G PGP G         G  G  G+ GPM            
Sbjct: 495 --PGERGPP--GRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAIL 550

Query: 559 -----GPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
                   GPAGP G  G  G +G PG  G  G PG  G  G  G  GP G  G  G +G
Sbjct: 551 QQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRG 610

Query: 614 EKVTSPSQHVP 624
              +  ++ +P
Sbjct: 611 RAGSDGARGMP 621



 Score = 33.5 bits (75), Expect = 0.62
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 115  PSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGP 151
            P      +GP G +G+ G  G  GPPG PG    P P
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577


>gi|22027599 alpha 1 type XIII collagen isoform 14 [Homo sapiens]
          Length = 664

 Score =  429 bits (1104), Expect = e-120
 Identities = 278/673 (41%), Positives = 332/673 (49%), Gaps = 135/673 (20%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPG--- 144
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR G  G PG  G   
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGRPGLPGSPGDAGLSI 143

Query: 145 --PQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGP 202
             P+GPPG  G +G  G  GP  +  K  H               KGD G  GPPG PGP
Sbjct: 144 IGPRGPPGQPGTRGFPGFPGPIGLDGKPGHPGP------------KGDMGLTGPPGQPGP 191

Query: 203 PGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGE 262
            G +G  G  G+   RG      E  +   QG  GP GPPG  G +G PG+PG     G 
Sbjct: 192 QGQKGEKGQCGEYPHRG------EQSQASIQGPPGPPGPPGPSGPLGHPGLPG---PMGP 242

Query: 263 PGLPGAVGQNGIPGPKGEPGEQG---EKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGES 319
           PGLPG       PGPKG+PG QG    KG+ G  G  G  G KG PG + AG+KGEPG  
Sbjct: 243 PGLPGP------PGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIP 296

Query: 320 GRPGQKGEPGLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGE 374
           G  G+KG  G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+
Sbjct: 297 GTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQ 354

Query: 375 RGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGN 434
            G PG PG KG++G +G +GP G KG +GE G             KG     E++DYNGN
Sbjct: 355 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGN 396

Query: 435 LHEALQRITTLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMG 488
           ++EALQ I TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG
Sbjct: 397 INEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMG 456

Query: 489 DPGMTGE---------KGGIGLPGLPGANGMKGEKGDSGMPGPQG--------------- 524
            PG  G          KG  G PG PG  G KGE G +G PG +G               
Sbjct: 457 PPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGL 516

Query: 525 PSIIGPPGPPGPHGPPGPMGPHGL------------------------------PGPKGT 554
           P   GPPGPPG  G PGP G  GL                              PGP GT
Sbjct: 517 PGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGT 576

Query: 555 DGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
            GP+G  GPAGPKGERG KG  G  GP G  GLPG  G PG  G  G RG+KG  G KG+
Sbjct: 577 PGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGD 636

Query: 615 K--VTSPSQHVPC 625
           K    +P    PC
Sbjct: 637 KGDQGAPGLDAPC 649



 Score =  156 bits (395), Expect = 5e-38
 Identities = 96/225 (42%), Positives = 114/225 (50%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 438 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 497

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 498 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 550

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGM---------------NGQKGEPGLPGAVGQNGIP 275
           GE+G  GPLG PG  G  G PG PG                 G KG+PG+ G  G  G+P
Sbjct: 551 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 610

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 611 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 655



 Score =  153 bits (386), Expect = 5e-37
 Identities = 102/239 (42%), Positives = 116/239 (48%), Gaps = 41/239 (17%)

Query: 395 PKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPP 454
           PK S G        G  G  G PG  GD G                    L++ GP GPP
Sbjct: 111 PKTSPGCNCPPAFQGPTGRPGLPGSPGDAG--------------------LSIIGPRGPP 150

Query: 455 GPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEK 514
           G  G    +G  G PG  G+DG+ G  G KGDMG   +TG       PG PG  G KGEK
Sbjct: 151 GQPGT---RGFPGFPGPIGLDGKPGHPGPKGDMG---LTGP------PGQPGPQGQKGEK 198

Query: 515 GDSGMPGPQGP----SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGER 570
           G  G    +G     SI GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ 
Sbjct: 199 GQCGEYPHRGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDP 255

Query: 571 GEKGAMGEPGPRGPYGLPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           G +G  G  G RG  G+PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 256 GIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 314


>gi|22027591 alpha 1 type XIII collagen isoform 10 [Homo sapiens]
          Length = 676

 Score =  429 bits (1104), Expect = e-120
 Identities = 277/679 (40%), Positives = 330/679 (48%), Gaps = 135/679 (19%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP                  P   GP G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP------------------PAFQGPTG 128

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQA--GPPGPPGPPGP 205
            PG  GDKG  G  G R+  P                    GD G +  GP GPPG PG 
Sbjct: 129 RPGLPGDKGAIGMPG-RVGSP--------------------GDAGLSIIGPRGPPGQPGT 167

Query: 206 RGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGM---NGQKGE 262
           RG P   G  GP G+ G PG PG  G+ GL GP G PG +G  G  G  G     G++ +
Sbjct: 168 RGFP---GFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRGEQSQ 224

Query: 263 PGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRP 322
             + G  G  G PGP G  G  G  G  G  G  G  G KGDPG    G  G  GE G P
Sbjct: 225 ASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQ--GYHGRKGERGMP 282

Query: 323 GQKGEPGLPGLPGLP--GIKGEPGFIGPQGE------PGLPGLPGTKGERGEAGPP---G 371
           G  G+ G  G PG+   G+KGEPG  G +GE      PGLPGL G KGE+G+AG     G
Sbjct: 283 GMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGG 342

Query: 372 RGERGEPGAPGPKGKQGESGTRG---PKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEI 428
           RGE G PG PGP G +GE+G  G   P G  GD+GE+G +G QGP GP G KG+ G  E+
Sbjct: 343 RGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEM 402

Query: 429 IDYNGNLHEALQRITTLTVTGPPG------PPGPQGLQGPKGEQGSPGIPGMDGEQGLKG 482
           +DYNGN++EALQ I TL + GPPG      PPG  G+ G KGE G PG PG DGE+G +G
Sbjct: 403 VDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRG 462

Query: 483 SKGDMGDPGMTGE---------KGGIGLPGLPGANGMKGEKGDSGMPGPQG--------- 524
             GDMG PG  G          KG  G PG PG  G KGE G +G PG +G         
Sbjct: 463 KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPG 522

Query: 525 ------PSIIGPPGPPGPHGPPGPMGPHGL------------------------------ 548
                 P   GPPGPPG  G PGP G  GL                              
Sbjct: 523 AEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGR 582

Query: 549 PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGD 608
           PGP GT GP+G  GPAGPKGERG KG  G  GP G  GLPG  G PG  G  G RG+KG 
Sbjct: 583 PGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGS 642

Query: 609 LGEKGEK--VTSPSQHVPC 625
            G KG+K    +P    PC
Sbjct: 643 RGPKGDKGDQGAPGLDAPC 661



 Score =  160 bits (404), Expect = 4e-39
 Identities = 102/223 (45%), Positives = 120/223 (53%), Gaps = 26/223 (11%)

Query: 411 QGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPG 470
           QGP G PG  GD+GA  +    G+  +A      L++ GP GPPG  G    +G  G PG
Sbjct: 124 QGPTGRPGLPGDKGAIGMPGRVGSPGDA-----GLSIIGPRGPPGQPGT---RGFPGFPG 175

Query: 471 IPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGP----S 526
             G+DG+ G  G KGDMG   +TG       PG PG  G KGEKG  G    +G     S
Sbjct: 176 PIGLDGKPGHPGPKGDMG---LTGP------PGQPGPQGQKGEKGQCGEYPHRGEQSQAS 226

Query: 527 IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYG 586
           I GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G
Sbjct: 227 IQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPG 283

Query: 587 LPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           +PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 284 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 326



 Score =  156 bits (395), Expect = 5e-38
 Identities = 96/225 (42%), Positives = 114/225 (50%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 450 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 509

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 510 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 562

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGM---------------NGQKGEPGLPGAVGQNGIP 275
           GE+G  GPLG PG  G  G PG PG                 G KG+PG+ G  G  G+P
Sbjct: 563 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 622

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 623 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 667


>gi|22027577 alpha 1 type XIII collagen isoform 5 [Homo sapiens]
          Length = 695

 Score =  427 bits (1099), Expect = e-119
 Identities = 275/696 (39%), Positives = 331/696 (47%), Gaps = 150/696 (21%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++                            GP GPPG PG RG
Sbjct: 138 AIGMPGRVGSPGDAGLSII----------------------------GPRGPPGQPGTRG 169

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPG--------------- 252
            PG  G   P G+ G PG PG  G+ GL GP G PG +G  G  G               
Sbjct: 170 FPGFPG---PIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMP 226

Query: 253 -------IPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDP 305
                  I  + G++ +  + G  G  G PGP G  G  G  G  G  G  G  G KGDP
Sbjct: 227 AALRSSQIIALKGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDP 286

Query: 306 GSSAAGIKGEPGESGRPGQKGEPGLPGLPGLP--GIKGEPGFIGPQGE------PGLPGL 357
           G    G  G  GE G PG  G+ G  G PG+   G+KGEPG  G +GE      PGLPGL
Sbjct: 287 GIQ--GYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGL 344

Query: 358 PGTKGERGEAGPP---GRGERGEPGAPGPKGKQGESGTRG---PKGSKGDRGEKGDSGAQ 411
            G KGE+G+AG     GRGE G PG PGP G +GE+G  G   P G  GD+GE+G +G Q
Sbjct: 345 LGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQ 404

Query: 412 GPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPG------PPGPQGLQGPKGE 465
           GP GP G KG+ G  E++DYNGN++EALQ I TL + GPPG      PPG  G+ G KGE
Sbjct: 405 GPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGE 464

Query: 466 QGSPGIPGMDGEQGLKGSKGDMGDPGMTGE---------KGGIGLPGLPGANGMKGEKGD 516
            G PG PG DGE+G +G  GDMG PG  G          KG  G PG PG  G KGE G 
Sbjct: 465 IGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQ 524

Query: 517 SGMPGPQG---------------PSIIGPPGPPGPHGPPGPMGPHGL------------- 548
           +G PG +G               P   GPPGPPG  G PGP G  GL             
Sbjct: 525 AGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEK 584

Query: 549 -----------------PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKD 591
                            PGP GT GP+G  GPAGPKGERG KG  G  GP G  GLPG  
Sbjct: 585 GDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLH 644

Query: 592 GEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
           G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 645 GPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 680



 Score =  157 bits (397), Expect = 3e-38
 Identities = 109/281 (38%), Positives = 124/281 (44%), Gaps = 59/281 (20%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ  
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQ-- 164

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
                                        PG  G  G  GP G  G PG PG  G+ GL 
Sbjct: 165 -----------------------------PGTRGFPGFPGPIGLDGKPGHPGPKGDMGLT 195

Query: 482 GSKGDMGDPGMTGEKGGIG-------LPGLPGAN------GMKGEKGDSGMPGPQGPSII 528
           G  G  G  G  GEKG  G       L  +P A        +KGE+  +        SI 
Sbjct: 196 GPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQSQA--------SIQ 247

Query: 529 GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLP 588
           GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G+P
Sbjct: 248 GPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPGMP 304

Query: 589 GKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           GK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 305 GKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 345



 Score =  156 bits (395), Expect = 5e-38
 Identities = 97/225 (43%), Positives = 116/225 (51%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 469 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 528

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 529 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 581

Query: 231 GEQGLMGPLG------------PPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP 275
           GE+G  GPLG            PPG  G IG PG  G  G+   KG+PG+ G  G  G+P
Sbjct: 582 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 641

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 642 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 686


>gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]
          Length = 717

 Score =  427 bits (1097), Expect = e-119
 Identities = 278/722 (38%), Positives = 335/722 (46%), Gaps = 180/722 (24%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP GPPG  G+ G  G+ G  G PG  G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCPPGPPGPTGRPGLPGDKGAIGMPGRVG 146

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
            PG         D G  ++ P+   G              +G  G  GP G  G PG  G
Sbjct: 147 SPG---------DAGLSIIGPRGPPGQPGT----------RGFPGFPGPIGLDGKPGHPG 187

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQG--------------------------------- 234
           P GD G  GP G PG  G+ G+ G+ G                                 
Sbjct: 188 PKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVR 247

Query: 235 --------------------LMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
                               + GP GPPG  G  G  G PG+ G  G PGLPG       
Sbjct: 248 LAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGP------ 301

Query: 275 PGPKGEPGEQG---EKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLP 331
           PGPKG+PG QG    KG+ G  G  G  G KG PG + AG+KGE                
Sbjct: 302 PGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGE---------------- 345

Query: 332 GLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPP---GRGERGEPGAPGPKGKQG 388
             PG+PG KGE G    +G PGLPGL G KGE+G+AG     GRGE G PG PGP G +G
Sbjct: 346 --PGIPGTKGEKG---AEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKG 400

Query: 389 ESGTRG---PKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTL 445
           E+G  G   P G  GD+GE+G +G QGP GP G KG+ G  E++DYNGN++EALQ I TL
Sbjct: 401 EAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTL 460

Query: 446 TVTGPPG------PPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE---- 495
            + GPPG      PPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G     
Sbjct: 461 ALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKD 520

Query: 496 -----KGGIGLPGLPGANGMKGEKGDSGMPGPQG---------------PSIIGPPGPPG 535
                KG  G PG PG  G KGE G +G PG +G               P   GPPGPPG
Sbjct: 521 GPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPG 580

Query: 536 PHGPPGPMGPHGL------------------------------PGPKGTDGPMGPHGPAG 565
             G PGP G  GL                              PGP GT GP+G  GPAG
Sbjct: 581 LQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAG 640

Query: 566 PKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHV 623
           PKGERG KG  G  GP G  GLPG  G PG  G  G RG+KG  G KG+K    +P    
Sbjct: 641 PKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDA 700

Query: 624 PC 625
           PC
Sbjct: 701 PC 702



 Score =  156 bits (395), Expect = 5e-38
 Identities = 97/225 (43%), Positives = 116/225 (51%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 491 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 550

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 551 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 603

Query: 231 GEQGLMGPLG------------PPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP 275
           GE+G  GPLG            PPG  G IG PG  G  G+   KG+PG+ G  G  G+P
Sbjct: 604 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 663

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 664 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 708



 Score =  147 bits (372), Expect = 2e-35
 Identities = 111/292 (38%), Positives = 125/292 (42%), Gaps = 82/292 (28%)

Query: 383 PKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRI 442
           PK   G +   GP G  G  G  GD GA G  G  G  GD G                  
Sbjct: 111 PKTSPGCNCPPGPPGPTGRPGLPGDKGAIGMPGRVGSPGDAG------------------ 152

Query: 443 TTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLP 502
             L++ GP GPPG  G    +G  G PG  G+DG+ G  G KGDMG   +TG       P
Sbjct: 153 --LSIIGPRGPPGQPGT---RGFPGFPGPIGLDGKPGHPGPKGDMG---LTGP------P 198

Query: 503 GLPGANGMKGEKGDSG----------------------------------MPGP------ 522
           G PG  G KGEKG  G                                   P P      
Sbjct: 199 GQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRT 258

Query: 523 -QGP----SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMG 577
            QG     SI GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G
Sbjct: 259 FQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHG 315

Query: 578 EPGPRGPYGLPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
             G RG  G+PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 316 RKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 367



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 38/109 (34%), Positives = 44/109 (40%), Gaps = 32/109 (29%)

Query: 112 REAPSECNCPAGPPGKRGKRGRRGESGPPGQPGP---------QGPPGPKGDKGEQGDQG 162
           R  P     P G PG  G +G RG  G PG  GP          GPPG KG++GE+G +G
Sbjct: 623 RPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKG 682

Query: 163 PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG--PPGPPGPRGPP 209
            R                       KGD+G  G PG   P P G  G P
Sbjct: 683 SRGP---------------------KGDKGDQGAPGLDAPCPLGEDGLP 710


>gi|22027593 alpha 1 type XIII collagen isoform 11 [Homo sapiens]
          Length = 686

 Score =  427 bits (1097), Expect = e-119
 Identities = 275/687 (40%), Positives = 332/687 (48%), Gaps = 141/687 (20%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++                            GP GPPG PG RG
Sbjct: 138 AIGMPGRVGSPGDAGLSII----------------------------GPRGPPGQPGTRG 169

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPG---------IPGMN- 257
            PG  G   P G+ G PG PG  G+ GL GP G PG +G  G  G         +P +N 
Sbjct: 170 FPGFPG---PIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRLLPLLNS 226

Query: 258 ---------------GQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEK 302
                          G++ +  + G  G  G PGP G  G  G  G  G  G  G  G K
Sbjct: 227 VRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPK 286

Query: 303 GDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLP--GIKGEPGFIGPQGE------PGL 354
           GDPG    G  G  GE G PG  G+ G  G PG+   G+KGEPG  G +GE      PGL
Sbjct: 287 GDPGIQ--GYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGL 344

Query: 355 PGLPGTKGERGEAGPP---GRGERGEPGAPGPKGKQGESGTRG---PKGSKGDRGEKGDS 408
           PGL G KGE+G+AG     GRGE G PG PGP G +GE+G  G   P G  GD+GE+G +
Sbjct: 345 PGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAA 404

Query: 409 GAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPP------GPPGPQGLQGP 462
           G QGP GP G KG+ G  E++DYNGN++EALQ I TL + GPP      GPPG  G+ G 
Sbjct: 405 GEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQ 464

Query: 463 KGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE---------KGGIGLPGLPGANGMKGE 513
           KGE G PG PG DGE+G +G  GDMG PG  G          KG  G PG PG  G KGE
Sbjct: 465 KGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGE 524

Query: 514 KGDSGMPGPQG---------------PSIIGPPGPPGPHGPPGPMGPHGLPGPK------ 552
            G +G PG +G               P   GPPGPPG  G PGP G  GL G K      
Sbjct: 525 TGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 584

Query: 553 ------------GTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP 600
                       GT GP+G  GPAGPKGERG KG  G  GP G  GLPG  G PG  G  
Sbjct: 585 GEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNR 644

Query: 601 GPRGEKGDLGEKGEK--VTSPSQHVPC 625
           G RG+KG  G KG+K    +P    PC
Sbjct: 645 GERGKKGSRGPKGDKGDQGAPGLDAPC 671



 Score =  158 bits (400), Expect = 1e-38
 Identities = 94/213 (44%), Positives = 112/213 (52%), Gaps = 25/213 (11%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 472 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 531

Query: 179 QQLIKRRLIKGDQGQAGPPG--------PPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKP 230
            +       KG+ G+ G PG        P GPPGP G  G  G  G  G+ G  GE G  
Sbjct: 532 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 584

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP---GPKGEPGEQ 284
           GE+G  GPLG PG  G IG PG  G  G+   KG+PG+ G  G  G+P   GP G+ G +
Sbjct: 585 GEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNR 644

Query: 285 GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
           GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 645 GERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 677



 Score =  152 bits (384), Expect = 9e-37
 Identities = 105/245 (42%), Positives = 122/245 (49%), Gaps = 48/245 (19%)

Query: 411 QGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPG 470
           QGP G PG  GD+GA  +    G+  +A      L++ GP GPPG  G    +G  G PG
Sbjct: 124 QGPTGRPGLPGDKGAIGMPGRVGSPGDA-----GLSIIGPRGPPGQPGT---RGFPGFPG 175

Query: 471 IPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSG------------ 518
             G+DG+ G  G KGDMG   +TG       PG PG  G KGEKG  G            
Sbjct: 176 PIGLDGKPGHPGPKGDMG---LTGP------PGQPGPQGQKGEKGQCGEYPHRLLPLLNS 226

Query: 519 ---MPGP-------QGP----SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPA 564
               P P       QG     SI GPPGPPGP GP GP+G  GLPGP G   P G  GP 
Sbjct: 227 VRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPP 283

Query: 565 GPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQH 622
           GPKG+ G +G  G  G RG  G+PGK G  G  G    G +GE G  G KGEK    S  
Sbjct: 284 GPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPG 343

Query: 623 VPCLI 627
           +P L+
Sbjct: 344 LPGLL 348



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 48/116 (41%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 511 KGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGER 570
           K   G +  P  QGP+  G PG PG  G  G  G  G PG  G    +GP GP G  G R
Sbjct: 112 KTSPGCNCPPAFQGPT--GRPGLPGDKGAIGMPGRVGSPGDAGLS-IIGPRGPPGQPGTR 168

Query: 571 GEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTSPSQHVPCL 626
           G  G  G  G  G  G PG  G+ GL G PG  G +G  GEKG+    P + +P L
Sbjct: 169 GFPGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRLLPLL 224


>gi|22027574 alpha 1 type XIII collagen isoform 4 [Homo sapiens]
          Length = 698

 Score =  426 bits (1095), Expect = e-119
 Identities = 276/699 (39%), Positives = 333/699 (47%), Gaps = 153/699 (21%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++                            GP GPPG PG RG
Sbjct: 138 AIGMPGRVGSPGDAGLSII----------------------------GPRGPPGQPGTRG 169

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPG---------IPGMN- 257
            PG  G   P G+ G PG PG  G+ GL GP G PG +G  G  G         +P +N 
Sbjct: 170 FPGFPG---PIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRLLPLLNS 226

Query: 258 ---------------GQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEK 302
                          G++ +  + G  G  G PGP G  G  G  G  G  G  G  G K
Sbjct: 227 VRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPK 286

Query: 303 GDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLP--GIKGEPGFIGPQGE------PGL 354
           GDPG    G  G  GE G PG  G+ G  G PG+   G+KGEPG  G +GE      PGL
Sbjct: 287 GDPGIQ--GYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGL 344

Query: 355 PGLPGTKGERGEAGPP---GRGERGEPGAPGPKGKQGESGTRG---PKGSKGDRGEKGDS 408
           PGL G KGE+G+AG     GRGE G PG PGP G +GE+G  G   P G  GD+GE+G +
Sbjct: 345 PGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAA 404

Query: 409 GAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPG------PPGPQGLQGP 462
           G QGP GP G KG+ G  E++DYNGN++EALQ I TL + GPPG      PPG  G+ G 
Sbjct: 405 GEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQ 464

Query: 463 KGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE---------KGGIGLPGLPGANGMKGE 513
           KGE G PG PG DGE+G +G  GDMG PG  G          KG  G PG PG  G KGE
Sbjct: 465 KGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGE 524

Query: 514 KGDSGMPGPQG---------------PSIIGPPGPPGPHGPPGPMGPHGL---------- 548
            G +G PG +G               P   GPPGPPG  G PGP G  GL          
Sbjct: 525 TGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 584

Query: 549 --------------------PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLP 588
                               PGP GT GP+G  GPAGPKGERG KG  G  GP G  GLP
Sbjct: 585 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 644

Query: 589 GKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
           G  G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 645 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 683



 Score =  156 bits (395), Expect = 5e-38
 Identities = 97/225 (43%), Positives = 116/225 (51%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 472 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 531

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 532 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 584

Query: 231 GEQGLMGPLG------------PPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP 275
           GE+G  GPLG            PPG  G IG PG  G  G+   KG+PG+ G  G  G+P
Sbjct: 585 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 644

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 645 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 689



 Score =  152 bits (384), Expect = 9e-37
 Identities = 105/245 (42%), Positives = 122/245 (49%), Gaps = 48/245 (19%)

Query: 411 QGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPG 470
           QGP G PG  GD+GA  +    G+  +A      L++ GP GPPG  G    +G  G PG
Sbjct: 124 QGPTGRPGLPGDKGAIGMPGRVGSPGDA-----GLSIIGPRGPPGQPGT---RGFPGFPG 175

Query: 471 IPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSG------------ 518
             G+DG+ G  G KGDMG   +TG       PG PG  G KGEKG  G            
Sbjct: 176 PIGLDGKPGHPGPKGDMG---LTGP------PGQPGPQGQKGEKGQCGEYPHRLLPLLNS 226

Query: 519 ---MPGP-------QGP----SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPA 564
               P P       QG     SI GPPGPPGP GP GP+G  GLPGP G   P G  GP 
Sbjct: 227 VRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPP 283

Query: 565 GPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQH 622
           GPKG+ G +G  G  G RG  G+PGK G  G  G    G +GE G  G KGEK    S  
Sbjct: 284 GPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPG 343

Query: 623 VPCLI 627
           +P L+
Sbjct: 344 LPGLL 348



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 48/116 (41%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 511 KGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGER 570
           K   G +  P  QGP+  G PG PG  G  G  G  G PG  G    +GP GP G  G R
Sbjct: 112 KTSPGCNCPPAFQGPT--GRPGLPGDKGAIGMPGRVGSPGDAGLS-IIGPRGPPGQPGTR 168

Query: 571 GEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTSPSQHVPCL 626
           G  G  G  G  G  G PG  G+ GL G PG  G +G  GEKG+    P + +P L
Sbjct: 169 GFPGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRLLPLL 224


>gi|22027571 alpha 1 type XIII collagen isoform 3 [Homo sapiens]
          Length = 700

 Score =  424 bits (1089), Expect = e-118
 Identities = 279/713 (39%), Positives = 332/713 (46%), Gaps = 179/713 (25%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPA---------GPPGKRGKRGRRGESG 138
            +  +V +LL +K   H  + R A +    CNCP          G PG +G  G  G  G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVG 146

Query: 139 PPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG 198
            PG  G  G PGP G  G+ G  GP                        KGD G  GPPG
Sbjct: 147 QPGTRGFPGFPGPIGLDGKPGHPGP------------------------KGDMGLTGPPG 182

Query: 199 PPGPPGPRGPPGDTGKDGPR----GMPGV------------------------------- 223
            PGP G +G  G  G+   R     MP                                 
Sbjct: 183 QPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTF 242

Query: 224 PGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGE 283
            GE  +   QG  GP GPPG  G +G PG+PG     G PGLPG       PGPKG+PG 
Sbjct: 243 QGEQSQASIQGPPGPPGPPGPSGPLGHPGLPG---PMGPPGLPGP------PGPKGDPGI 293

Query: 284 QG---EKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIK 340
           QG    KG+ G  G  G  G KG PG + AG+KGE                  PG+PG K
Sbjct: 294 QGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGE------------------PGIPGTK 335

Query: 341 GEPGFIGPQGEPGLPGLPGTKGERGEAGPP---GRGERGEPGAPGPKGKQGESGTRG--- 394
           GE G    +G PGLPGL G KGE+G+AG     GRGE G PG PGP G +GE+G  G   
Sbjct: 336 GEKG---AEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVG 392

Query: 395 PKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPG-- 452
           P G  GD+GE+G +G QGP GP G KG+ G  E++DYNGN++EALQ I TL + GPPG  
Sbjct: 393 PPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLP 452

Query: 453 ----PPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE---------KGGI 499
               PPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G          KG  
Sbjct: 453 GQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGEN 512

Query: 500 GLPGLPGANGMKGEKGDSGMPGPQG---------------PSIIGPPGPPGPHGPPGPMG 544
           G PG PG  G KGE G +G PG +G               P   GPPGPPG  G PGP G
Sbjct: 513 GHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKG 572

Query: 545 PHGL------------------------------PGPKGTDGPMGPHGPAGPKGERGEKG 574
             GL                              PGP GT GP+G  GPAGPKGERG KG
Sbjct: 573 EAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKG 632

Query: 575 AMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
             G  GP G  GLPG  G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 633 DPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 685



 Score =  281 bits (719), Expect = 1e-75
 Identities = 184/461 (39%), Positives = 216/461 (46%), Gaps = 100/461 (21%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPR----MVFPKINHGFLS 176
           P GPPG  G  G  G  GP G PG  GPPGPKGD G QG  G +    M      HG   
Sbjct: 257 PPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKG 316

Query: 177 AD----------------------------QQLIKRRLIKGD--------QGQAGPPGPP 200
           A                               L+ ++  KGD        +G+ GPPG P
Sbjct: 317 APGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLP 376

Query: 201 GPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGP---------------------- 238
           GPPGP+G  G  G+ GP G PG  GE G  GEQG  GP                      
Sbjct: 377 GPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEA 436

Query: 239 ---------LGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQ---GE 286
                    +GPPG  G IG PG PG+ GQKGE GLPG  G +G  GP+G+PG+    G 
Sbjct: 437 LQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGP 496

Query: 287 KGDAGENGPKGDTGEKGDPGS-SAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGF 345
           +G  G++GP G  GE G PGS    G KGE G++G PG+KGE G  G PG   + G PG 
Sbjct: 497 QGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAE-VPGLPGP 555

Query: 346 IGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGE 404
            GP G PGL G+PG KGE G  G  G +G +GE G  GP G  G SG  G  G  G  G 
Sbjct: 556 EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGP 615

Query: 405 KGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKG 464
            G  G  GP+G  G KGD G                      +TGP G  G  GL GP G
Sbjct: 616 IGVPGPAGPKGERGSKGDPG----------------------MTGPTGAAGLPGLHGPPG 653

Query: 465 EQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLP 505
           ++G+ G  G  G +G KG KGD G PG+      +G  GLP
Sbjct: 654 DKGNRGERGKKGSRGPKGDKGDQGAPGLDA-PCPLGEDGLP 693



 Score =  137 bits (346), Expect = 2e-32
 Identities = 101/260 (38%), Positives = 115/260 (44%), Gaps = 62/260 (23%)

Query: 427 EIIDYNGNLHEALQRITTLTVTG---PP---GPPGPQGLQGPKGEQGSPGIPGMDGEQGL 480
           +++D    LH   +R    T  G   PP   GP G  GL G KG  G PG  G  G +G 
Sbjct: 94  QLLDEKWKLHSRRRREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGQPGTRGF 153

Query: 481 KGSKGDMG---DPGMTGEKGGIGL---PGLPGANGMKGEKGDSG---------------- 518
            G  G +G    PG  G KG +GL   PG PG  G KGEKG  G                
Sbjct: 154 PGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALR 213

Query: 519 ------------------MPGP-------QGP----SIIGPPGPPGPHGPPGPMGPHGLP 549
                              P P       QG     SI GPPGPPGP GP GP+G  GLP
Sbjct: 214 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLP 273

Query: 550 GPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP--GPRGEKG 607
           GP G   P G  GP GPKG+ G +G  G  G RG  G+PGK G  G  G    G +GE G
Sbjct: 274 GPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG 330

Query: 608 DLGEKGEKVTSPSQHVPCLI 627
             G KGEK    S  +P L+
Sbjct: 331 IPGTKGEKGAEGSPGLPGLL 350



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 38/109 (34%), Positives = 44/109 (40%), Gaps = 32/109 (29%)

Query: 112 REAPSECNCPAGPPGKRGKRGRRGESGPPGQPGP---------QGPPGPKGDKGEQGDQG 162
           R  P     P G PG  G +G RG  G PG  GP          GPPG KG++GE+G +G
Sbjct: 606 RPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKG 665

Query: 163 PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG--PPGPPGPRGPP 209
            R                       KGD+G  G PG   P P G  G P
Sbjct: 666 SRGP---------------------KGDKGDQGAPGLDAPCPLGEDGLP 693


>gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens]
          Length = 657

 Score =  422 bits (1086), Expect = e-118
 Identities = 273/682 (40%), Positives = 326/682 (47%), Gaps = 160/682 (23%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP    G+ G RG  G  GP G  G  G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCPPVFQGQPGTRGFPGFPGPIGLDGKPG 146

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
            PGPKG                                    D G  GPPG PGP G +G
Sbjct: 147 HPGPKG------------------------------------DMGLTGPPGQPGPQGQKG 170

Query: 208 PPGDTGKDGPR----GMPG---------VPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIP 254
             G  G+   R     MP          + GE  +   QG  GP GPPG  G +G PG+P
Sbjct: 171 EKGQCGEYPHRECLSSMPAALRSSQIIALKGEQSQASIQGPPGPPGPPGPSGPLGHPGLP 230

Query: 255 GMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG---EKGDAGENGPKGDTGEKGDPGSSAAG 311
           G     G PGLPG       PGPKG+PG QG    KG+ G  G  G  G KG PG + AG
Sbjct: 231 G---PMGPPGLPGP------PGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAG 281

Query: 312 IKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPP- 370
           +KGE                  PG+PG KGE G    +G PGLPGL G KGE+G+AG   
Sbjct: 282 MKGE------------------PGIPGTKGEKG---AEGSPGLPGLLGQKGEKGDAGNSI 320

Query: 371 --GRGERGEPGAPGPKGKQGESGTRG---PKGSKGDRGEKGDSGAQGPRGPPGQKGDQGA 425
             GRGE G PG PGP G +GE+G  G   P G  GD+GE+G +G QGP GP G KG+ G 
Sbjct: 321 GGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGK 380

Query: 426 TEIIDYNGNLHEALQRITTLTVTGPPG------PPGPQGLQGPKGEQGSPGIPGMDGEQG 479
            E++DYNGN++EALQ I TL + GPPG      PPG  G+ G KGE G PG PG DGE+G
Sbjct: 381 GEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKG 440

Query: 480 LKGSKGDMGDPGMTGE---------KGGIGLPGLPGANGMKGEKGDSGMPGPQG------ 524
            +G  GDMG PG  G          KG  G PG PG  G KGE G +G PG +G      
Sbjct: 441 PRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKG 500

Query: 525 ---------PSIIGPPGPPGPHGPPGPMGPHGL--------------------------- 548
                    P   GPPGPPG  G PGP G  GL                           
Sbjct: 501 NPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGL 560

Query: 549 ---PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGE 605
              PGP GT GP+G  GPAGPKGERG KG  G  GP G  GLPG  G PG  G  G RG+
Sbjct: 561 DGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGK 620

Query: 606 KGDLGEKGEK--VTSPSQHVPC 625
           KG  G KG+K    +P    PC
Sbjct: 621 KGSRGPKGDKGDQGAPGLDAPC 642



 Score =  156 bits (395), Expect = 5e-38
 Identities = 96/225 (42%), Positives = 114/225 (50%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 431 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 490

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 491 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 543

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGM---------------NGQKGEPGLPGAVGQNGIP 275
           GE+G  GPLG PG  G  G PG PG                 G KG+PG+ G  G  G+P
Sbjct: 544 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 603

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 604 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 648



 Score =  142 bits (358), Expect = 9e-34
 Identities = 94/226 (41%), Positives = 110/226 (48%), Gaps = 37/226 (16%)

Query: 427 EIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGD 486
           +++D    LH   +R    T  G   PP  QG  G +G  G PG  G+DG+ G  G KGD
Sbjct: 94  QLLDEKWKLHSRRRREAPKTSPGCNCPPVFQGQPGTRGFPGFPGPIGLDGKPGHPGPKGD 153

Query: 487 MGDPGMTGEKGGIGLPGLPGANGMKGEKGDSG----------------------MPGPQG 524
           MG   +TG       PG PG  G KGEKG  G                      + G Q 
Sbjct: 154 MG---LTGP------PGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQS 204

Query: 525 P-SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRG 583
             SI GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG
Sbjct: 205 QASIQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERG 261

Query: 584 PYGLPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
             G+PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 262 MPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 307


>gi|22027603 alpha 1 type XIII collagen isoform 16 [Homo sapiens]
          Length = 660

 Score =  421 bits (1083), Expect = e-118
 Identities = 272/685 (39%), Positives = 326/685 (47%), Gaps = 163/685 (23%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP    G+ G RG  G  GP G  G  G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCPPVFQGQPGTRGFPGFPGPIGLDGKPG 146

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
            PGPKG                                    D G  GPPG PGP G +G
Sbjct: 147 HPGPKG------------------------------------DMGLTGPPGQPGPQGQKG 170

Query: 208 PPGDTGKDGPRGMPGV----------------PGEPGKPGEQGLMGPLGPPGQKGSIGAP 251
             G  G+   R +P +                 GE  +   QG  GP GPPG  G +G P
Sbjct: 171 EKGQCGEYPHRLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHP 230

Query: 252 GIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG---EKGDAGENGPKGDTGEKGDPGSS 308
           G+PG     G PGLPG       PGPKG+PG QG    KG+ G  G  G  G KG PG +
Sbjct: 231 GLPG---PMGPPGLPGP------PGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIA 281

Query: 309 AAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAG 368
            AG+KGE                  PG+PG KGE G    +G PGLPGL G KGE+G+AG
Sbjct: 282 VAGMKGE------------------PGIPGTKGEKG---AEGSPGLPGLLGQKGEKGDAG 320

Query: 369 PP---GRGERGEPGAPGPKGKQGESGTRG---PKGSKGDRGEKGDSGAQGPRGPPGQKGD 422
                GRGE G PG PGP G +GE+G  G   P G  GD+GE+G +G QGP GP G KG+
Sbjct: 321 NSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGE 380

Query: 423 QGATEIIDYNGNLHEALQRITTLTVTGPPG------PPGPQGLQGPKGEQGSPGIPGMDG 476
            G  E++DYNGN++EALQ I TL + GPPG      PPG  G+ G KGE G PG PG DG
Sbjct: 381 PGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDG 440

Query: 477 EQGLKGSKGDMGDPGMTGE---------KGGIGLPGLPGANGMKGEKGDSGMPGPQG--- 524
           E+G +G  GDMG PG  G          KG  G PG PG  G KGE G +G PG +G   
Sbjct: 441 EKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 500

Query: 525 ------------PSIIGPPGPPGPHGPPGPMGPHGL------------------------ 548
                       P   GPPGPPG  G PGP G  GL                        
Sbjct: 501 EKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGA 560

Query: 549 ------PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGP 602
                 PGP GT GP+G  GPAGPKGERG KG  G  GP G  GLPG  G PG  G  G 
Sbjct: 561 SGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGE 620

Query: 603 RGEKGDLGEKGEK--VTSPSQHVPC 625
           RG+KG  G KG+K    +P    PC
Sbjct: 621 RGKKGSRGPKGDKGDQGAPGLDAPC 645



 Score =  156 bits (395), Expect = 5e-38
 Identities = 96/225 (42%), Positives = 114/225 (50%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 434 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 493

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 494 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 546

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGM---------------NGQKGEPGLPGAVGQNGIP 275
           GE+G  GPLG PG  G  G PG PG                 G KG+PG+ G  G  G+P
Sbjct: 547 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 606

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 607 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 651



 Score =  141 bits (355), Expect = 2e-33
 Identities = 96/229 (41%), Positives = 111/229 (48%), Gaps = 40/229 (17%)

Query: 427 EIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGD 486
           +++D    LH   +R    T  G   PP  QG  G +G  G PG  G+DG+ G  G KGD
Sbjct: 94  QLLDEKWKLHSRRRREAPKTSPGCNCPPVFQGQPGTRGFPGFPGPIGLDGKPGHPGPKGD 153

Query: 487 MGDPGMTGEKGGIGLPGLPGANGMKGEKGDSG---------------MPGP-------QG 524
           MG   +TG       PG PG  G KGEKG  G                P P       QG
Sbjct: 154 MG---LTGP------PGQPGPQGQKGEKGQCGEYPHRLLPLLNSVRLAPPPVIKRRTFQG 204

Query: 525 P----SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPG 580
                SI GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G
Sbjct: 205 EQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKG 261

Query: 581 PRGPYGLPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
            RG  G+PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 262 ERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 310


>gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens]
          Length = 690

 Score =  417 bits (1072), Expect = e-116
 Identities = 275/697 (39%), Positives = 332/697 (47%), Gaps = 157/697 (22%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++ P+                   G  GQ G  G PG PGP G
Sbjct: 138 AIGMPGRVGSPGDAGLSIIGPR-------------------GPPGQPGTRGFPGFPGPIG 178

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQ----------------------- 244
             G  G  GP+G  G+ G PG+PG QG  G  G  G+                       
Sbjct: 179 LDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALK 238

Query: 245 ------------------------------KGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
                                         +G  G PG PG +G  G PGLPG +G  G+
Sbjct: 239 LLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGL 298

Query: 275 ---PGPKGEPGEQ---GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
              PGPKG+PG Q   G KG+ G  G  G  G KG PG + AG+KGEPG  G  G+KG  
Sbjct: 299 PGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAE 358

Query: 329 GLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGP 383
           G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+ G PG PG 
Sbjct: 359 GSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQVGPPGQPGD 416

Query: 384 KGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT 443
           KG++G +G +GP G KG +GE G             KG     E++DYNGN++EALQ I 
Sbjct: 417 KGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGNINEALQEIR 458

Query: 444 TLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE-- 495
           TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G   
Sbjct: 459 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPG 518

Query: 496 -------KGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGL 548
                  KG  G PG PG  G KGE G +G P P  P   GPPGPPG  G PGP G  GL
Sbjct: 519 KDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPKGEAGL 578

Query: 549 PGPK------------------GTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGK 590
            G K                  GT GP+G  GPAGPKGERG KG  G  GP G  GLPG 
Sbjct: 579 DGAKGEKGFQGEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGL 638

Query: 591 DGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
            G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 639 HGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 675



 Score =  160 bits (405), Expect = 3e-39
 Identities = 91/206 (44%), Positives = 110/206 (53%), Gaps = 26/206 (12%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
           GPPG  G++G RG+ G  G PGPQGPPG  G  G +G+ G         H     ++   
Sbjct: 491 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENG---------HPGSPGEKGE- 540

Query: 183 KRRLIKGDQGQAGPP-----GPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMG 237
                KG+ GQAG P     GP GPPGP G  G  G  G  G+ G  GE G  GE+G  G
Sbjct: 541 -----KGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRG 595

Query: 238 PLGPPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP---GPKGEPGEQGEKGDAG 291
           PLG PG  G IG PG  G  G+   KG+PG+ G  G  G+P   GP G+ G +GE+G  G
Sbjct: 596 PLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKG 655

Query: 292 ENGPKGDTGEKGDPGSSAAGIKGEPG 317
             GPKGD G++G PG  A    GE G
Sbjct: 656 SRGPKGDKGDQGAPGLDAPCPLGEDG 681



 Score =  154 bits (390), Expect = 2e-37
 Identities = 109/283 (38%), Positives = 125/283 (44%), Gaps = 41/283 (14%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ G
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPG 166

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
            +G                        GP G  G  G  GPKG+ G  G PG  G QG K
Sbjct: 167 TRGFPGF-------------------PGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQK 207

Query: 482 GSKGDMGD----------PGMTGEKGGIGLPGLPGANGMKGE-----KGDSGMPGPQGPS 526
           G KG  G+          P        I L  LP  N ++       K  +        S
Sbjct: 208 GEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQAS 267

Query: 527 IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYG 586
           I GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G
Sbjct: 268 IQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPG 324

Query: 587 LPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           +PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 325 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 367


>gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens]
          Length = 702

 Score =  416 bits (1070), Expect = e-116
 Identities = 276/709 (38%), Positives = 333/709 (46%), Gaps = 169/709 (23%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++ P+                   G  GQ G  G PG PGP G
Sbjct: 138 AIGMPGRVGSPGDAGLSIIGPR-------------------GPPGQPGTRGFPGFPGPIG 178

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQ----------------------- 244
             G  G  GP+G  G+ G PG+PG QG  G  G  G+                       
Sbjct: 179 LDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALK 238

Query: 245 ------------------------------KGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
                                         +G  G PG PG +G  G PGLPG +G  G+
Sbjct: 239 LLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGL 298

Query: 275 ---PGPKGEPGEQ---GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
              PGPKG+PG Q   G KG+ G  G  G  G KG PG + AG+KGEPG  G  G+KG  
Sbjct: 299 PGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAE 358

Query: 329 GLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGP 383
           G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+ G PG PG 
Sbjct: 359 GSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQVGPPGQPGD 416

Query: 384 KGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT 443
           KG++G +G +GP G KG +GE G             KG     E++DYNGN++EALQ I 
Sbjct: 417 KGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGNINEALQEIR 458

Query: 444 TLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE-- 495
           TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G   
Sbjct: 459 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPG 518

Query: 496 -------KGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGL 548
                  KG  G PG PG  G KGE G +G P P  P   GPPGPPG  G PGP G  GL
Sbjct: 519 KDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPKGEAGL 578

Query: 549 ------------------------------PGPKGTDGPMGPHGPAGPKGERGEKGAMGE 578
                                         PGP GT GP+G  GPAGPKGERG KG  G 
Sbjct: 579 DGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGM 638

Query: 579 PGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
            GP G  GLPG  G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 639 TGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 687



 Score =  159 bits (402), Expect = 7e-39
 Identities = 94/211 (44%), Positives = 110/211 (52%), Gaps = 24/211 (11%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 491 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 550

Query: 179 QQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGK------PGE 232
                   + G  G  GPPGPPG  G  GP G+ G DG +G  G  GE G       PG 
Sbjct: 551 --------VPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGA 602

Query: 233 QGLMGPLGPPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP---GPKGEPGEQGE 286
            GL G  GPPG  G IG PG  G  G+   KG+PG+ G  G  G+P   GP G+ G +GE
Sbjct: 603 SGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGE 662

Query: 287 KGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
           +G  G  GPKGD G++G PG  A    GE G
Sbjct: 663 RGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 693



 Score =  154 bits (390), Expect = 2e-37
 Identities = 109/283 (38%), Positives = 125/283 (44%), Gaps = 41/283 (14%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ G
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPG 166

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
            +G                        GP G  G  G  GPKG+ G  G PG  G QG K
Sbjct: 167 TRGFPGF-------------------PGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQK 207

Query: 482 GSKGDMGD----------PGMTGEKGGIGLPGLPGANGMKGE-----KGDSGMPGPQGPS 526
           G KG  G+          P        I L  LP  N ++       K  +        S
Sbjct: 208 GEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQAS 267

Query: 527 IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYG 586
           I GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G
Sbjct: 268 IQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPG 324

Query: 587 LPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           +PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 325 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 367


>gi|22027589 alpha 1 type XIII collagen isoform 9 [Homo sapiens]
          Length = 688

 Score =  415 bits (1067), Expect = e-116
 Identities = 277/703 (39%), Positives = 329/703 (46%), Gaps = 171/703 (24%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR G  G PG  G  G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGRPGLPGQPGTRGFPG 143

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
            PGP G  G+ G  GP                        KGD G  GPPG PGP G +G
Sbjct: 144 FPGPIGLDGKPGHPGP------------------------KGDMGLTGPPGQPGPQGQKG 179

Query: 208 PPGDTGKDGPR----GMPGV-------------------------------PGEPGKPGE 232
             G  G+   R     MP                                  GE  +   
Sbjct: 180 EKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASI 239

Query: 233 QGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG---EKGD 289
           QG  GP GPPG  G +G PG+PG     G PGLPG       PGPKG+PG QG    KG+
Sbjct: 240 QGPPGPPGPPGPSGPLGHPGLPG---PMGPPGLPGP------PGPKGDPGIQGYHGRKGE 290

Query: 290 AGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPG----- 344
            G  G  G  G KG PG + AG+KGEPG  G  G+KG  G PGLPGL G KGE G     
Sbjct: 291 RGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNS 350

Query: 345 FIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGE 404
             G +GEPG PGLPG  G +GEAG    G+ G PG PG KG++G +G +GP G KG +GE
Sbjct: 351 IGGGRGEPGPPGLPGPPGPKGEAGVD--GQVGPPGQPGDKGERGAAGEQGPDGPKGSKGE 408

Query: 405 KGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPP------GPPGPQG 458
            G             KG     E++DYNGN++EALQ I TL + GPP      GPPG  G
Sbjct: 409 PG-------------KG-----EMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPG 450

Query: 459 LQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE---------KGGIGLPGLPGANG 509
           + G KGE G PG PG DGE+G +G  GDMG PG  G          KG  G PG PG  G
Sbjct: 451 IPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKG 510

Query: 510 MKGEKGDSGMPGPQG---------------PSIIGPPGPPGPHGPPGPMGPHGL------ 548
            KGE G +G PG +G               P   GPPGPPG  G PGP G  GL      
Sbjct: 511 EKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGE 570

Query: 549 ------------------------PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGP 584
                                   PGP GT GP+G  GPAGPKGERG KG  G  GP G 
Sbjct: 571 KGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGA 630

Query: 585 YGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
            GLPG  G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 631 AGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 673



 Score =  156 bits (395), Expect = 5e-38
 Identities = 96/225 (42%), Positives = 114/225 (50%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 462 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 521

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 522 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 574

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGM---------------NGQKGEPGLPGAVGQNGIP 275
           GE+G  GPLG PG  G  G PG PG                 G KG+PG+ G  G  G+P
Sbjct: 575 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 634

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 635 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 679



 Score =  138 bits (347), Expect = 2e-32
 Identities = 98/251 (39%), Positives = 110/251 (43%), Gaps = 56/251 (22%)

Query: 427 EIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGD 486
           +++D    LH   +R    T    PG   P   QGP G  G PG PG  G  G  G  G 
Sbjct: 94  QLLDEKWKLHSRRRREAPKT---SPGCNCPPAFQGPTGRPGLPGQPGTRGFPGFPGPIGL 150

Query: 487 MGDPGMTGEKGGIGL---PGLPGANGMKGEKGDSG------------------------- 518
            G PG  G KG +GL   PG PG  G KGEKG  G                         
Sbjct: 151 DGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKL 210

Query: 519 ---------MPGP-------QGP----SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPM 558
                     P P       QG     SI GPPGPPGP GP GP+G  GLPGP G   P 
Sbjct: 211 LPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMG---PP 267

Query: 559 GPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP--GPRGEKGDLGEKGEKV 616
           G  GP GPKG+ G +G  G  G RG  G+PGK G  G  G    G +GE G  G KGEK 
Sbjct: 268 GLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKG 327

Query: 617 TSPSQHVPCLI 627
              S  +P L+
Sbjct: 328 AEGSPGLPGLL 338


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  415 bits (1066), Expect = e-116
 Identities = 244/547 (44%), Positives = 284/547 (51%), Gaps = 46/547 (8%)

Query: 113 EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
           E P     P GP G  G  GR G  G PG PGP GPPGP G  G  G+  P++     ++
Sbjct: 111 EGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQL-----SY 165

Query: 173 GFLSADQQLIKRRLIKGDQGQAGP---PGPPGPPGPRG---PPGDTGKDG------PRGM 220
           G+   D++      + G  G +GP   PGPPG PGP+G   PPG+ G+ G      PRG 
Sbjct: 166 GY---DEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGP 222

Query: 221 PGVPG------EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
           PG PG      E GKPG  G  GP GP G +G  G  G+PGM G +G  GL GA G  G 
Sbjct: 223 PGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP 282

Query: 275 PGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGS-SAAGIKGEPGESGRPGQKGEPGLPGL 333
            GPKGEPG  GE G  G+ GP+G  GE+G PG+   AG +G  G +G  G  G  G  G 
Sbjct: 283 AGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGP 342

Query: 334 PGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGT 392
           PG PG  G  G  GPQG  G  G  G +GE G  GP G  G  G PGA G  G +G +G 
Sbjct: 343 PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402

Query: 393 RGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPG 452
            G  G+ G  G +G SG QGP GPPG KG+ G        G+   A      + V GPPG
Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDT-GAKGEPGPVGVQGPPG 461

Query: 453 P------------PGPQGLQGPKGEQGSP---GIPGMDGEQGLKGSKGDMGDPGMTGEKG 497
           P            PGP GL GP GE+G P   G PG DG  G KG  G+ G PG  G KG
Sbjct: 462 PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKG 521

Query: 498 GIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGP 557
             G  G PG  G+ G KG +G PG  GP   G  GPPGP G  G  GP G PG +G  G 
Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPD--GKTGPPGPAGQDGRPGPPGPPGARGQAGV 579

Query: 558 MGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVT 617
           MG  GP G  GE G+ G  G PGP G  G  GKDGE G  G PGP G  G+ GE+G   +
Sbjct: 580 MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGS 639

Query: 618 SPSQHVP 624
              Q +P
Sbjct: 640 PGFQGLP 646



 Score =  404 bits (1038), Expect = e-112
 Identities = 244/570 (42%), Positives = 280/570 (49%), Gaps = 103/570 (18%)

Query: 112 REAPSECNCPA--GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQGPRMV 166
           R  P E   P   GP G RG  G  G +GPPG  GP GPPG     G KGE G QGPR  
Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363

Query: 167 FPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGP------RGM 220
                                +G QG  G PGPPGP G  GP G+ G DG        G 
Sbjct: 364 ---------------------EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402

Query: 221 PGVPGEPGKPGEQGLMGPLGP---PGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGP 277
           PG+ G PG PG +G  GP GP   PG KG+ G PG PG  G  G  G PG VG  G PGP
Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGP 462

Query: 278 KGEPGEQGEKGDAGENGPKGDTGEKGDPGSSA-------------AGIKGEPGESG---R 321
            GE G++G +G+ G  G  G  GE+G PGS               AG +G PG +G    
Sbjct: 463 AGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522

Query: 322 PGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGA 380
           PG+ G PG  GLPG  G+ G PG  GP G+ G PG  G  G  G  GPPG RG+ G  G 
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF 582

Query: 381 PGPKG------KQGESGTRGPKGSKGDRGEKGDSGAQGP---RGPPGQKGDQGATEIIDY 431
           PGPKG      K GE G  GP G+ G  G+ G++GAQGP    GP G++G+QG      +
Sbjct: 583 PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642

Query: 432 NGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPG 491
            G    A          GPPG  G  G QG  G+ G+PG  G  GE+G  G +G  G PG
Sbjct: 643 QGLPGPA----------GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG 692

Query: 492 MTGEKGGIGLPG------------------LPGANGMKGEKGDSGMPGPQGPSIIGPPGP 533
             G +G  G PG                   PG  GM GE+G +G+PGP+G    G  GP
Sbjct: 693 PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDR--GDAGP 750

Query: 534 PGPHGPPGPMGPHGLPGPKGTDGPMG---------PHGPAGPKGERGEKGAMGEPGPRGP 584
            G  G PG  G  GL GP G  GP G         P GPAGP G RG  G  GEPGP GP
Sbjct: 751 KGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP 810

Query: 585 YGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
            G  G    PG DG PG +GE GD G KG+
Sbjct: 811 AGFAGP---PGADGQPGAKGEPGDAGAKGD 837



 Score =  397 bits (1019), Expect = e-110
 Identities = 234/544 (43%), Positives = 268/544 (49%), Gaps = 64/544 (11%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGP---------------PGPKGDKGEQGDQGPRM 165
           P GP G+ GKRG RGE GP G PGP G                 GPKG  GE+G  GP  
Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGP-- 516

Query: 166 VFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG 225
             PK + G      +      + G +G  G PG PGP G  GPPG  G+DG  G PG PG
Sbjct: 517 AGPKGSPGEAGRPGEAG----LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572

Query: 226 EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
             G+ G  G  GP G  G+ G  G  G+PG  G  G  G  G  G  G PGP G  GE+G
Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632

Query: 286 EKGDAGENGPKGDTGEKGDPGSSA-AGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPG 344
           E+G AG  G +G  G  G PG +   G +G PG+ G PG  G  G  G PG  G++G PG
Sbjct: 633 EQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG 692

Query: 345 FIGPQGEPGLPGLPGTKGERGEAGPPGR----------GERGEPGAPGPKGKQGESGTRG 394
             GP+G  G PG  G KG+ G  G PG           GERG  G PGPKG +G++G +G
Sbjct: 693 PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKG 752

Query: 395 PKGSKGDRGEKGDSGAQGPRGP---PGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPP 451
             GS G  G +G +G  GP GP   PG KG+ G +      G       R       G P
Sbjct: 753 ADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR-------GEP 805

Query: 452 GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMK 511
           GPPGP G  GP G  G PG  G  G+ G KG  G  G  G  G  G IG  G PGA G +
Sbjct: 806 GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGAR 865

Query: 512 GEKGD---------SGMPGPQGPS-IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPH 561
           G  G          +G  GP GPS   GPPGPPGP G  G  GP G  GP G  G +GP 
Sbjct: 866 GSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP 925

Query: 562 GPAGPKGERGE------KGAMGEPGP------RGPYGLPGKDGEPGLDGFPGPRGEKGDL 609
           GP GP GE+G        GA G PGP      RG  GLPG+ GE G  G PGP GE G  
Sbjct: 926 GPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985

Query: 610 GEKG 613
           G  G
Sbjct: 986 GPSG 989



 Score =  396 bits (1017), Expect = e-110
 Identities = 240/561 (42%), Positives = 271/561 (48%), Gaps = 76/561 (13%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
            GPPG  G  G RGE GP G PG QG PGP G  GE G  G + V      G L A     
Sbjct: 620  GPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGV-----PGDLGAPGPSG 674

Query: 183  KR--RLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240
             R  R   G++G  GPPGP GP G  G PG+ G  G  G PG PG  G PG QG+ G  G
Sbjct: 675  ARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERG 734

Query: 241  P---PGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGP-- 295
                PG KG  G  G  G +G  G+ G+ G  G  G PGP G PG++GE G +G  GP  
Sbjct: 735  AAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794

Query: 296  -KGDTGEKGDPGSSA-AGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPG 353
             +G  G++G+PG    AG  G PG  G+PG KGEPG  G  G  G  G  G  GP G  G
Sbjct: 795  ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 354  LPGLPGTKGERGEAGPPGR----------------GERGEPGAPGPKGKQGESGTRG--- 394
              G PG KG RG AGPPG                 G  G PG PGP GK+G  G RG   
Sbjct: 855  NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG 914

Query: 395  ---------PKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATE---IIDYNGNLHE----- 437
                     P G  G  GEKG  GA GP G PG  G QG      ++   G   E     
Sbjct: 915  PAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974

Query: 438  --------ALQRITTLT-VTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGS---KG 485
                      Q  +  +   GPPGP GP GL GP GE G  G PG +G  G  GS   KG
Sbjct: 975  LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034

Query: 486  DMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP 545
            D G+ G  G  G  G PG PG  G  G+ GD G  GP GP+  GP GP G  GP GP GP
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPA--GPVGPVGARGPAGPQGP 1092

Query: 546  HG------------LPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGE 593
             G            + G +G  G  GP GP G  GE+G  GA G  GPRGP G  G  G+
Sbjct: 1093 RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152

Query: 594  PGLDGFPGPRGEKGDLGEKGE 614
             GL+G PGP G  G  G  G+
Sbjct: 1153 DGLNGLPGPIGPPGPRGRTGD 1173



 Score =  384 bits (986), Expect = e-106
 Identities = 235/549 (42%), Positives = 265/549 (48%), Gaps = 76/549 (13%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG-PRMVFPKINHGFLSADQ 179
           P GPPG  GK G  GE+G PG+PG +GPPGP+G +G  G  G P M   K + GF   D 
Sbjct: 219 PRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGM---KGHRGFSGLDG 275

Query: 180 QLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGK---DGPRGMPGVPGEPGKPGEQGLM 236
                   KGD G AGP G PG PG  G PG  G     G RG PG PG  G  G  G  
Sbjct: 276 A-------KGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT 328

Query: 237 GPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPK 296
           G  GPPG  G  G PG PG  G KGE G  G  G  G  G +GEPG  G  G AG  G  
Sbjct: 329 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP 388

Query: 297 GDTGEKGDPGSSAA-GIKGEPG------------ESGRPGQKG---EPGLPGLPGLPGIK 340
           G  G+ G  G++ A GI G PG              G PG KG   EPG PG  G  G K
Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448

Query: 341 GEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR----GERGEPGAPGPKGKQGESGTRGPK 396
           GEPG +G QG PG  G  G +G RGE GP G     GERG PG+ G  G  G +G +GP 
Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPA 508

Query: 397 GSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGP 456
           G +G  G  G  G+ G  G PG+ G  GA  +    G+              G  GPPGP
Sbjct: 509 GERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP----------DGKTGPPGP 558

Query: 457 QGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGD 516
            G  G  G  G PG  G  G  G  G KG  G+PG  GE+G  G PG  G  G  GE G 
Sbjct: 559 AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA 618

Query: 517 SGMPGPQGPSIIGPPGPPGP---------HGPPGPMGPHGLPGPKGTDGPMGPHGPAGPK 567
            G PGP GP+  G  G  GP          GP GP G  G PG +G  G +G  GP+G +
Sbjct: 619 QGPPGPAGPA--GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676

Query: 568 GER---GEKGAMGEPGPRGPY------------------GLPGKDGEPGLDGFPGPRGEK 606
           GER   GE+G  G PGP GP                   G PG  G PGL G PG RG  
Sbjct: 677 GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736

Query: 607 GDLGEKGEK 615
           G  G KG++
Sbjct: 737 GLPGPKGDR 745



 Score =  328 bits (841), Expect = 9e-90
 Identities = 196/453 (43%), Positives = 224/453 (49%), Gaps = 77/453 (16%)

Query: 111  AREAPSECNCP--------AGPPGKRGKRGRRGE---------SGPPGQPGPQGPPGPKG 153
            AR AP +   P        AGPPG  G+ G +GE         +GPPG  GP GPPGP G
Sbjct: 795  ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 154  DKGEQGDQGPR-MVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDT 212
            + G  G +G R    P    GF  A  ++       G  G AGPPGPPGP G  G  G  
Sbjct: 855  NVGAPGAKGARGSAGPPGATGFPGAAGRVGP----PGPSGNAGPPGPPGPAGKEGGKGPR 910

Query: 213  GKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQN 272
            G+ GP G PG  G PG PG  G  G  G  G  G+ G PG  G+ GQ+G  GLPG  G+ 
Sbjct: 911  GETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGER 970

Query: 273  ---GIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPG 329
               G+PGP GEPG+QG  G +GE GP G  G          G+ G PGESGR G  G  G
Sbjct: 971  GFPGLPGPSGEPGKQGPSGASGERGPPGPMG--------PPGLAGPPGESGREGAPGAEG 1022

Query: 330  LPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGE 389
             PG  G PG KG+ G  GP G PG PG PG  G  G AG    G+RGE G  GP G  G 
Sbjct: 1023 SPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGK--SGDRGETGPAGPAGPVGP 1080

Query: 390  SGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTG 449
             G RGP G +G RG+KG++G QG RG  G +G  G                      + G
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSG----------------------LQG 1118

Query: 450  PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANG 509
            PPGPPG  G QGP                G  G  G  G PG  G  G  GL GLPG  G
Sbjct: 1119 PPGPPGSPGEQGP---------------SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIG 1163

Query: 510  MKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGP 542
              G +G +G  GP     +GPPGPPGP GPPGP
Sbjct: 1164 PPGPRGRTGDAGP-----VGPPGPPGPPGPPGP 1191



 Score =  301 bits (771), Expect = 1e-81
 Identities = 190/459 (41%), Positives = 212/459 (46%), Gaps = 69/459 (15%)

Query: 197 PGPPGPPGPRGPPGDTGKDGPRGMP--GVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIP 254
           PG   P G   P    G + P      GV G  G  G +G  GP GPPG+ G  G PG+P
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 255 GMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKG 314
           G  G                PGP G PG  G        G      EK   G S  G  G
Sbjct: 142 GPPGP---------------PGPPGPPGLGGNFAPQLSYG----YDEKSTGGISVPGPMG 182

Query: 315 EPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR-G 373
             G  G PG  G PG  G  G PG  GEPG  GP G  G PG PG  G+ GEAG PGR G
Sbjct: 183 PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242

Query: 374 ERGEPGAPGPK---------------------GKQGESGTRGPKGSKGDRGEKGDSGAQG 412
           ERG PG  G +                     G +G++G  GPKG  G  GE G  G  G
Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302

Query: 413 PRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIP 472
           PRG PG++G  GA       GN             TG  GPPGP G  GP G  G+ G  
Sbjct: 303 PRGLPGERGRPGAPGPAGARGN----------DGATGAAGPPGPTGPAGPPGFPGAVGAK 352

Query: 473 GMDGEQGLKGSKGDM---GDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPG----PQGP 525
           G  G QG +GS+G     G+PG  G  G  G  G PGA+G  G KG +G PG    P  P
Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412

Query: 526 SIIGPPGPPGPHGPPGPMGPHGLP---------GPKGTDGPMGPHGPAGPKGERGEKGAM 576
              GP GP GP GPPGP G  G P         G KG  GP+G  GP GP GE G++GA 
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 577 GEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK 615
           GEPGP G  G PG+ G PG  GFPG  G  G  G  GE+
Sbjct: 473 GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER 511



 Score =  246 bits (627), Expect = 6e-65
 Identities = 140/325 (43%), Positives = 172/325 (52%), Gaps = 25/325 (7%)

Query: 109  RIAREAPSECNCPAGPPG---KRGKRGRRGESGP---PGQPGPQGPPGPKGDKGEQGDQG 162
            R+    PS    P GPPG   K G +G RGE+GP   PG+ GP GPPGP G+KG  G  G
Sbjct: 882  RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941

Query: 163  PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGP---PGDTGKDGPRG 219
            P           ++  + ++     +G++G  G PGP G PG +GP    G+ G  GP G
Sbjct: 942  PAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMG 1001

Query: 220  MPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKG 279
             PG+ G PG+ G +G  G  G PG+ GS GA G  G  G  G PG PGA G  G  GP G
Sbjct: 1002 PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAG 1061

Query: 280  EPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGI 339
            + G++GE G AG  GP G  G +G  G    G +G+ GE+G  G +            GI
Sbjct: 1062 KSGDRGETGPAGPAGPVGPVGARGPAGPQ--GPRGDKGETGEQGDR------------GI 1107

Query: 340  KGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSK 399
            KG  GF G QG PG PG PG +G  G +GP   G RG PG+ G  GK G +G  GP G  
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGP--AGPRGPPGSAGAPGKDGLNGLPGPIGPP 1165

Query: 400  GDRGEKGDSGAQGPRGPPGQKGDQG 424
            G RG  GD+G  GP GPPG  G  G
Sbjct: 1166 GPRGRTGDAGPVGPPGPPGPPGPPG 1190



 Score =  220 bits (561), Expect = 3e-57
 Identities = 129/306 (42%), Positives = 150/306 (49%), Gaps = 30/306 (9%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPG---PQGPPGPKGDKGEQGDQGPR------------- 164
            P GP GK G +G RGE+GP G+PG   P GPPGP G+KG  G  GP              
Sbjct: 897  PPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAG 956

Query: 165  ------MVFPKINHGF--LSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDG 216
                  +   +   GF  L        ++   G  G+ GPPGP GPPG  GPPG++G++G
Sbjct: 957  QRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREG 1016

Query: 217  PRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPG 276
              G  G PG  G PG +G  G  GP G  G+ GAPG PG  G  G+ G  G  G  G  G
Sbjct: 1017 APGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076

Query: 277  PKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGL 336
            P G  G +G  G  G  G KG+TGE+GD      GIKG  G SG  G  G PG PG  G 
Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGD-----RGIKGHRGFSGLQGPPGPPGSPGEQGP 1131

Query: 337  PGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGP 395
             G  G  G  GP G  G PG  G  G  G  GPPG RG  G+ G  GP G  G  G  GP
Sbjct: 1132 SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191

Query: 396  KGSKGD 401
              +  D
Sbjct: 1192 PSAGFD 1197


>gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens]
          Length = 705

 Score =  412 bits (1060), Expect = e-115
 Identities = 276/712 (38%), Positives = 334/712 (46%), Gaps = 172/712 (24%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++ P+                   G  GQ G  G PG PGP G
Sbjct: 138 AIGMPGRVGSPGDAGLSIIGPR-------------------GPPGQPGTRGFPGFPGPIG 178

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQ----------------------- 244
             G  G  GP+G  G+ G PG+PG QG  G  G  G+                       
Sbjct: 179 LDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALK 238

Query: 245 ------------------------------KGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
                                         +G  G PG PG +G  G PGLPG +G  G+
Sbjct: 239 LLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGL 298

Query: 275 ---PGPKGEPGEQ---GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
              PGPKG+PG Q   G KG+ G  G  G  G KG PG + AG+KGEPG  G  G+KG  
Sbjct: 299 PGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAE 358

Query: 329 GLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGP 383
           G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+ G PG PG 
Sbjct: 359 GSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQVGPPGQPGD 416

Query: 384 KGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT 443
           KG++G +G +GP G KG +GE G             KG     E++DYNGN++EALQ I 
Sbjct: 417 KGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGNINEALQEIR 458

Query: 444 TLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE-- 495
           TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G   
Sbjct: 459 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPG 518

Query: 496 -------KGGIGLPGLPGANGMKGEKGDSGMPGPQG---------------PSIIGPPGP 533
                  KG  G PG PG  G KGE G +G PG +G               P   GPPGP
Sbjct: 519 KDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGP 578

Query: 534 PGPHGPPGPMGPHGLPGPK------------------GTDGPMGPHGPAGPKGERGEKGA 575
           PG  G PGP G  GL G K                  GT GP+G  GPAGPKGERG KG 
Sbjct: 579 PGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGD 638

Query: 576 MGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
            G  GP G  GLPG  G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 639 PGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 690



 Score =  158 bits (400), Expect = 1e-38
 Identities = 94/213 (44%), Positives = 112/213 (52%), Gaps = 25/213 (11%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 491 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 550

Query: 179 QQLIKRRLIKGDQGQAGPPG--------PPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKP 230
            +       KG+ G+ G PG        P GPPGP G  G  G  G  G+ G  GE G  
Sbjct: 551 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 603

Query: 231 GEQGLMGPLGPPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP---GPKGEPGEQ 284
           GE+G  GPLG PG  G IG PG  G  G+   KG+PG+ G  G  G+P   GP G+ G +
Sbjct: 604 GEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNR 663

Query: 285 GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
           GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 664 GERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 696



 Score =  154 bits (390), Expect = 2e-37
 Identities = 109/283 (38%), Positives = 125/283 (44%), Gaps = 41/283 (14%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ G
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPG 166

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
            +G                        GP G  G  G  GPKG+ G  G PG  G QG K
Sbjct: 167 TRGFPGF-------------------PGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQK 207

Query: 482 GSKGDMGD----------PGMTGEKGGIGLPGLPGANGMKGE-----KGDSGMPGPQGPS 526
           G KG  G+          P        I L  LP  N ++       K  +        S
Sbjct: 208 GEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQAS 267

Query: 527 IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYG 586
           I GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G
Sbjct: 268 IQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPG 324

Query: 587 LPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           +PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 325 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 367


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  412 bits (1059), Expect = e-115
 Identities = 252/574 (43%), Positives = 298/574 (51%), Gaps = 85/574 (14%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
            GP G  G  G +G+ G PG  GP+G PG KGDKG+ G  G      K++ G +       
Sbjct: 894  GPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQ---- 949

Query: 183  KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTG---KDGPRGMPGVPGEPGKPGEQGLMGPL 239
                 KGDQG+ G  GP G  G RG PG  G   KDG  G PG PG  G PG  G  G  
Sbjct: 950  -----KGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAP 1004

Query: 240  GPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG-------------- 285
            G PG KGS+G  G+PG  G+KG PG+PG  G  G+PG KG  GE+G              
Sbjct: 1005 GLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRG 1064

Query: 286  EKGDAGENGPKGDTGEKGDPGS-------SAAGIKGEPGE------SGRPGQKGEPGLPG 332
            EKGD G  G  G  GEKG+ GS        + G+KG PG        G PG+KG+ GLPG
Sbjct: 1065 EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPG 1124

Query: 333  LPGLPGIKGE------PGFIGP---QGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGP 383
            L G+PG+KGE      PG  GP   +GEPG  G+PG+ GE+GE G PGRG  G PGA G 
Sbjct: 1125 LDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGD 1184

Query: 384  KGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT 443
            KG +GE G  G  GS G  G KG+ G  GP GP GQ G  G+              Q   
Sbjct: 1185 KGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQP 1244

Query: 444  TLT-VTGPPGPPGPQGLQGPKGEQGSPG------IPGMDGEQGLKGSKGDMGDPGMTGEK 496
             L  + GP GPPG  G+ G KG++G+PG      +PG  G+ G +G  G  G PG+TG K
Sbjct: 1245 GLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSK 1304

Query: 497  GGIGLPG---------LPGANGMKGEKGDSGMPGPQG-PSIIGPPGP----------PGP 536
            G +G PG         LPG  G+KG++GD G+PG +G P   GPPGP          PGP
Sbjct: 1305 GDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGP 1364

Query: 537  HGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKG------ERGEKGAMGEPGPRGPYGLPGK 590
             GPPG  G  GLPGPKG  G  G  G  GP G        G+KG MG  GP GP G PG 
Sbjct: 1365 EGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGP 1424

Query: 591  DGEPGLDGFPGPRGEKGDLG-EKGEKVTSPSQHV 623
               PG DG PG  G  G    + G  VT  SQ +
Sbjct: 1425 ---PGPDGLPGSMGPPGTPSVDHGFLVTRHSQTI 1455



 Score =  387 bits (994), Expect = e-107
 Identities = 248/576 (43%), Positives = 292/576 (50%), Gaps = 122/576 (21%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPG-----PKGDKGEQGDQGPRMVFPKINHGFLSA 177
            GPPG +G RG   E GPPG PG  G PG     P G +G  G QGP              
Sbjct: 773  GPPGLQGIRG---EPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGP-------------- 815

Query: 178  DQQLIKRRLIKGDQGQAG-----PPGPPGPPGPRGPPGDTGKDGPRGMPG---VPGEPGK 229
               L     IKG++G  G      PGP G  G +G PG TG+ G  G+PG    PG PG 
Sbjct: 816  -PGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGF 874

Query: 230  PGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGE------ 283
            PG +G MG +G PGQ GS G  G PG+ G+KG+ G PG+ G  G PG KG+ G+      
Sbjct: 875  PGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGK 934

Query: 284  ------------QGEKGDAGENG---PKGDTGEKGDPGSSA-------AGIKGEPGESGR 321
                        +G+KGD GE G   P G+ G +GDPG+         AG  G+PG  G 
Sbjct: 935  PGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGD 994

Query: 322  PGQKGEPGLPGLPG------------LPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGP 369
            PG  G PG PGLPG             PG KG PG  GPQG PGLPG  G KGE+G+AGP
Sbjct: 995  PGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGP 1054

Query: 370  PG------RGERGE------PGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPP 417
            PG      RGE+G+      PG+PG KG++G  G  G  GS G +G  G  G  G  G P
Sbjct: 1055 PGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLP 1114

Query: 418  GQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGE 477
            G+KGD+G   +    G   EA          G PG PGP G  G KGE GS GIPG  GE
Sbjct: 1115 GEKGDKGLPGLDGIPGVKGEA----------GLPGTPGPTGPAGQKGEPGSDGIPGSAGE 1164

Query: 478  QGL-----------------KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMP 520
            +G                  KGSKG++G PG+ G       PG+PG+   KGE+G  G P
Sbjct: 1165 KGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGS------PGIPGS---KGEQGFMGPP 1215

Query: 521  GPQG-PSIIGPPG--PPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMG 577
            GPQG P + G PG    GP G  GP G  GLPG  G  GP G  G  G KG++G  G  G
Sbjct: 1216 GPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPG 1275

Query: 578  EPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
             PG  GP G PG  G PG+ G PG  G KGD+G  G
Sbjct: 1276 APGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPG 1311



 Score =  375 bits (964), Expect = e-104
 Identities = 235/567 (41%), Positives = 283/567 (49%), Gaps = 95/567 (16%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGP--QGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
            G PG  G+ G  GE G  GQPG    GPPGPKG  G  GD GP                 
Sbjct: 667  GFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGT-------------- 712

Query: 181  LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240
                    G  G  G PG PG  G +G PG  G  G +G+PG+PG PG PGE+G +G  G
Sbjct: 713  -------PGRPGFNGLPGNPGVQGQKGEPG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764

Query: 241  PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPG-----PKGEPGEQGEKGDAGENGP 295
             PG+ G+IG PG+ G+ G+ G PGLPG+VG  G+PG      +G PG QG  G +G  G 
Sbjct: 765  VPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGI 824

Query: 296  KGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLP 355
            KG+ G  G PG    G KG+ G  G PG  G+ GLPGLPG  G  G PGF G +GE G+ 
Sbjct: 825  KGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVM 884

Query: 356  GLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKG-------------- 400
            G PG  G  G  G PG  GE+G+ G PG  G +G+ G +G KG  G              
Sbjct: 885  GTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMG 944

Query: 401  -DRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGP--- 456
              +G+KGD G +G  GP G+KG +G        G   +A Q        G PGP G    
Sbjct: 945  SMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQ-------PGQPGPKGDPGI 997

Query: 457  ------QGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKG-----------GI 499
                   GL GPKG  G  G+PG  GE+G+ G  G  G PG+ G+KG           GI
Sbjct: 998  SGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI 1057

Query: 500  GLPGL------------PGANGMKGEKGDSGMPG-PQGPSIIGPPGP---PGPHGPPGPM 543
            G+PGL            PG+ G KGEKG  G+PG P  P + G PG    PG  G PG  
Sbjct: 1058 GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEK 1117

Query: 544  GPHGL------PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLD 597
            G  GL      PG KG  G  G  GP GP G++GE G+ G PG  G  G PG  G  G  
Sbjct: 1118 GDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGR-GFP 1176

Query: 598  GFPGPRGEKGDLGEKGEKVTSPSQHVP 624
            GFPG +G+KG  GE G    + S  +P
Sbjct: 1177 GFPGAKGDKGSKGEVGFPGLAGSPGIP 1203



 Score =  371 bits (952), Expect = e-102
 Identities = 240/558 (43%), Positives = 270/558 (48%), Gaps = 66/558 (11%)

Query: 115 PSECNCPAGPPGKRGKRGRRG--------ESGPPGQPGPQGPPGPKGDKG---------- 156
           P +   P G PG+RG++G RG         SG  G PGP G PGP G  G          
Sbjct: 378 PGQAGAP-GFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQP 436

Query: 157 -EQGDQGPRMVFPKINH-GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGK 214
              GDQGP  +  +    G +    Q  +  LI    G  GPPGP GPPG  G PG  G 
Sbjct: 437 GPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGA 496

Query: 215 DGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGA-------------PGIPGMNGQKG 261
            G RG+PG  G  G PG QG  G +G PG KG  G              PG PG  G  G
Sbjct: 497 KGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTG 556

Query: 262 EPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGR 321
             G PG  G  G+PGPKG PG  G KG+ G  G  G  G +GD G       G  G  G 
Sbjct: 557 RAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGD 616

Query: 322 PGQKGEPGLPGLPGLPGIKGEPGFI-------GPQGEPGLPGLPGTKGERGEAGPPGR-- 372
            GQ G PG PG PGLPG KGEPG I       G +G PG PG PG +G+RG  G PGR  
Sbjct: 617 KGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG 676

Query: 373 --GERGE--------PGAPGPKGKQGESGTRGPKGSKGD---RGEKGDSGAQGPRGPP-- 417
             GE+G         PG PGPKG  G  G  GP G+ G     G  G+ G QG +G P  
Sbjct: 677 LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736

Query: 418 GQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGE 477
           G  G +G   +    G   E    I    V G  G  GP GLQG +GE G PG+PG  G 
Sbjct: 737 GLPGLKGLPGLPGIPGTPGEK-GSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGS 795

Query: 478 QGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPH 537
            G+ G    +G PG  G  GG G PGL G  G+KGEKG  G PG   P   GP G  G  
Sbjct: 796 PGVPG----IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMP---GPKGDKGAQ 848

Query: 538 GPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLD 597
           G PG  G  GLPG  G  G  G  G  G KGE G  G  G+PG  GP G PG  GE G  
Sbjct: 849 GLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDH 908

Query: 598 GFPGPRGEKGDLGEKGEK 615
           GFPG  G +GD G KG+K
Sbjct: 909 GFPGSSGPRGDPGLKGDK 926



 Score =  367 bits (941), Expect = e-101
 Identities = 236/559 (42%), Positives = 274/559 (49%), Gaps = 75/559 (13%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSAD---- 178
           G PG  G  G +G  GPPG  GP GPPGP G  GE+G  G     PK + G         
Sbjct: 182 GTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPG 241

Query: 179 ---QQLIKRR---LIKGDQGQAGPP-----------GPPGPPGPRGPPGDTGKDGPRGMP 221
              Q  ++ +     KG++GQ G P           G PG PGPRG PG  G  G +G P
Sbjct: 242 VPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSP 301

Query: 222 GVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGM------NGQKGEPGLPGAVGQNGIP 275
           G PGEPG P   GL+G  GP G+KG  G PG PG+       G+KGE G PG  G  G P
Sbjct: 302 GFPGEPGYP---GLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEP 358

Query: 276 GPKGEPGEQGE--------KGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGE 327
           GPKG PG  G+         G AG  G  G+ GEKGD G     +   PG SGR G  G 
Sbjct: 359 GPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSL---PGPSGRDGLPGP 415

Query: 328 PGLPGLPGLPG-----IKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR--------GE 374
           PG PG PG PG     ++ +PG  G QG PG+PG PG  GE GE G  G         G 
Sbjct: 416 PGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGY 475

Query: 375 RGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGN 434
           RG PG  GP G+ G  G  G KG +G  G  G +G  GP+G PG  G  GA       G 
Sbjct: 476 RGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAK---GEPGE 532

Query: 435 LHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDP---G 491
            +  L+        G PG PG  G  G  G  G PG+PG  G  G  G KG+ G P   G
Sbjct: 533 FYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVG 592

Query: 492 MTGEKGGIGLPGLPGAN--GMKGEKGDSGMP-GPQGPSIIGPPGPPGPHGP-PGPMGPHG 547
             G +G  G PG PG    G  G+KG +G P GP  P + GP G PG   P PGP G  G
Sbjct: 593 FPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEG 652

Query: 548 LPGPKGTDGPMGPHGPAGPKGE---RGEKGAMGE--------PGPRGPYGLPGKDGEPGL 596
           LPG  G  GP G  G  G  G     GEKGA+G+        PGP+G  GLPG  G PG 
Sbjct: 653 LPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGT 712

Query: 597 DGFPGPRGEKGDLGEKGEK 615
            G PG  G  G+ G +G+K
Sbjct: 713 PGRPGFNGLPGNPGVQGQK 731



 Score =  366 bits (940), Expect = e-101
 Identities = 244/588 (41%), Positives = 281/588 (47%), Gaps = 128/588 (21%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
           P G PG  G +G RG  GPPG PG  G PGP G  G +GD G       + H        
Sbjct: 119 PPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPG-----EILGH-------- 165

Query: 181 LIKRRLIKGDQGQAGPPGPPGPP------GPRGPPGDTGKDGPRGMPGVPGEPGK----- 229
            +   L+KG++G  G PG PGPP      GP GPPG TG  GP G PG PGE G+     
Sbjct: 166 -VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSF 224

Query: 230 ------PGEQGLMGPLGPPGQ--------------KGSIGAPGIPGMN--GQKGEPGLPG 267
                  G+QG+ GP G PGQ              KG  G PG  GM   G+KGEPG PG
Sbjct: 225 QGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPG 284

Query: 268 AVGQNGIPGPKGE------PGEQGEKGDAGENGPKGDTGEKGDP-------GSSAAGIKG 314
             G+ G  G KGE      PGE G  G  G  GP+G+ GE G P       G+   G KG
Sbjct: 285 PRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKG 344

Query: 315 EPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR-- 372
           E G  G PG +GEPG  G PGLPG  G PG   P G+ G PG PG +GE+G+ G PG   
Sbjct: 345 ERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVP-GQAGAPGFPGERGEKGDRGFPGTSL 403

Query: 373 -GERGEPGAPGPKGKQGESGTRG--------PKGSKGDRGEKGDSGAQGPRGPPGQKGDQ 423
            G  G  G PGP G  G  G  G          G  GD+G  G  G  G  G  G+KG +
Sbjct: 404 PGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQK 463

Query: 424 GATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGS 483
           G + +I                 + G  GPPGP   QGP GE G PG PG  G++GL G 
Sbjct: 464 GESCLI---------------CDIDGYRGPPGP---QGPPGEIGFPGQPGAKGDRGLPGR 505

Query: 484 KGDMGDPGMTGEKGGIGLPGLPGANG-------MKGEKGDSGMPGPQG-------PSIIG 529
            G  G PG  G  G IG PG  G  G       +KG+KGD G PG  G       P   G
Sbjct: 506 DGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDG 565

Query: 530 PPGPPGPHGPP---------GPMGPHGLPGPKGTDGPMGP--HGPAGP---KGERGEKGA 575
            PG PGP G P         GP G  G PG +G  GP GP  +GPAGP   KG+ G  G 
Sbjct: 566 HPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGG 625

Query: 576 MGEPGPRGPYGLPGK----------DGEPGLDGFPGPRGEKGDLGEKG 613
            G PG  GP G PGK          +G PG  GFPGP+G++G  G  G
Sbjct: 626 PGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPG 673



 Score =  364 bits (935), Expect = e-100
 Identities = 226/525 (43%), Positives = 263/525 (50%), Gaps = 91/525 (17%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG-PRMVFPKINHGFLSADQ 179
            P G  G RG  G  G  G  GQ G  G PGPKGD G  G  G P +  PK + G +    
Sbjct: 961  PIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMG--- 1017

Query: 180  QLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGE------------- 226
                   + G  G+ G PG PGP G  G PGD G  G +G  G PG              
Sbjct: 1018 -------LPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQG 1070

Query: 227  ----PGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPG 282
                PG PGE+G  G +G PG  GS G  G PG  G  G PGLPG  G  G+PG  G PG
Sbjct: 1071 IAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPG 1130

Query: 283  EQGEKGDAGENGPKGDTGEKGDPGSS----AAGIKGEPGESGR-----PGQKGE------ 327
             +GE G  G  GP G  G+KG+PGS     +AG KGEPG  GR     PG KG+      
Sbjct: 1131 VKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGE 1190

Query: 328  ---PGLPGLPGLPGIKGEPGFI---GPQGEPGLPGLPG--TKGERGEAGPPGRGERGEPG 379
               PGL G PG+PG KGE GF+   GPQG+PGLPG PG  T+G +G+ GP  +G+ G PG
Sbjct: 1191 VGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGP--QGQPGLPG 1248

Query: 380  APGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEAL 439
             PGP G  G  G  G KG KG+ G  G  G  GP+G PG                     
Sbjct: 1249 LPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPG--------------------- 1287

Query: 440  QRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQ---GLKGSKGDMGDPGMTGEK 496
                     G PG  G  G+ G KG+ G PG+PG  G +   GL+G KGD GD G+ G K
Sbjct: 1288 -------FQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAK 1340

Query: 497  GGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDG 556
            G  G PG PG   +   KG+ G+PGP+     GPPG  G  G PGP G  G+ G  G  G
Sbjct: 1341 GLPGPPGPPGPYDI--IKGEPGLPGPE-----GPPGLKGLQGLPGPKGQQGVTGLVGIPG 1393

Query: 557  PMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPG 601
            P G  G  G  G++GE G  G  GPRG  G PG DG PG  G PG
Sbjct: 1394 PPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPG 1438



 Score =  361 bits (926), Expect = 1e-99
 Identities = 247/601 (41%), Positives = 287/601 (47%), Gaps = 122/601 (20%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
           G PG +G  G  GE G PG+PGP+G PG  GDKGE+G  G    FP    G+      LI
Sbjct: 264 GEPGFQGMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSPG----FPG-EPGYPG----LI 313

Query: 183 KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPP 242
            R+  +G++G+AGPPGPPG     GP G+ G+ G  G PG  GEPG  G  GL G  GPP
Sbjct: 314 GRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPP 373

Query: 243 G--QKGSIGAPGIPGMNGQKGEPG-----LPGAVGQNGIPGPKGE--------------- 280
           G    G  GAPG PG  G+KG+ G     LPG  G++G+PGP G                
Sbjct: 374 GLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVE 433

Query: 281 -----PGEQGEKGDAGENGPKGDTGEKGDPGSSAA-----GIKGEPGESGRPGQKGEPGL 330
                PG+QG  G  G+ G  G+ GEKG  G S       G +G PG  G PG+ G PG 
Sbjct: 434 CQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQ 493

Query: 331 PGLP---GLPGIKGEPGFIGPQGEPGLPGLPGTKGERGE--------------------- 366
           PG     GLPG  G  G  GPQG PGL G PG KGE GE                     
Sbjct: 494 PGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPG 553

Query: 367 ----AGPPGRGERGEPGAPGPKGKQGE---SGTRGPKGSKGDRGEKGDSGAQGP--RGPP 417
               AG PGR   G PG PGPKG  G     G RGP G  G  G +GD+G  GP   GP 
Sbjct: 554 MTGRAGSPGRD--GHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPA 611

Query: 418 GQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGL---------QGPKGEQGS 468
           G  GD+G        G+      +     +   PGPPG +GL         QG +G  G+
Sbjct: 612 GPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGT 671

Query: 469 PGIPGMDGE-----------------QGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMK 511
           PG PG+ GE                 +G+ G  GDMG PG  G  G  GLPG PG  G K
Sbjct: 672 PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQK 731

Query: 512 GE--------KGDSGMPG----PQGPSIIGPPGPPGPH---GPPGPMGPHGLPGPKGTDG 556
           GE        KG  G+PG    P     IG PG PG H   GPPG  G  G PGP G  G
Sbjct: 732 GEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPG 791

Query: 557 PMGPHG--PAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDG--FPGPRGEKGDLGEK 612
            +G  G    GP G RG  G  G PG  GP G+ G+ G PG  G   PGP+G+KG  G  
Sbjct: 792 SVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLP 851

Query: 613 G 613
           G
Sbjct: 852 G 852



 Score =  341 bits (875), Expect = 1e-93
 Identities = 207/488 (42%), Positives = 248/488 (50%), Gaps = 64/488 (13%)

Query: 189 GDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSI 248
           G +GQ G  G PG  G  G PG  G +GP+G PG  G+ G+PG  G  G  GPPG  G  
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102

Query: 249 GAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSS 308
           G PG+PG+ GQ G PG PG  G NG  G +G  G  G  G AG  GP G  G KGDPG  
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162

Query: 309 AAGIKGE--PGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGE 366
              + G    GE G PG  G PG PGLPGL G  G PGF GP G PG PG PG KG+ G 
Sbjct: 163 LGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGL 222

Query: 367 AGPPGRGERGEPGAPGPKG--------KQGESGTRGPKGSKGDR--------GEKGDSGA 410
           +    +G++G+ G  GP G        ++G+  T+G KG KG+         GEKG+ G 
Sbjct: 223 SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGK 282

Query: 411 QGPRGPPGQKGDQGATEIIDYNG--NLHEALQRITTLTVTGPPGPPGPQGL------QGP 462
            GPRG PG+ GD+G      + G       + R       G  GPPGP G+       G 
Sbjct: 283 PGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGE 342

Query: 463 KGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTG--EKGGIGLPGLPGANGMKGEKGDSG-- 518
           KGE+G PG PG  GE G KG  G  G PG  G    G  G PG PG  G KG++G  G  
Sbjct: 343 KGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTS 402

Query: 519 MPGPQG-PSIIGPPGPPGP--------------HGPPGPMGPHGLPGPKGTDGPMGP--- 560
           +PGP G   + GPPG PGP               GPPG  GP G+PG  G  G +G    
Sbjct: 403 LPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQ 462

Query: 561 -------------HGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKG 607
                         GP GP+G  GE G  G+PG +G  GLPG+D   G+ G PGP+G  G
Sbjct: 463 KGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRD---GVAGVPGPQGTPG 519

Query: 608 DLGEKGEK 615
            +G+ G K
Sbjct: 520 LIGQPGAK 527



 Score =  245 bits (626), Expect = 8e-65
 Identities = 159/383 (41%), Positives = 187/383 (48%), Gaps = 61/383 (15%)

Query: 296 KGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLP 355
           KG     G       G+KG+ GE G PG +G  G PG+ G  G +G PG  G  GEPGLP
Sbjct: 28  KGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLP 87

Query: 356 GLPGTKGERGEAGPPGR----GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ 411
           G  GT+G  G +G PG     G  G+ G PGP G  G +GT+G +G  G  G  G +G  
Sbjct: 88  GTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNP 147

Query: 412 GPRGPPGQKGDQGATEIIDYNGNLHEALQR--------------------ITTLTVTGPP 451
           GP G PG KGD G  EI+ +   +    +R                    +     TGPP
Sbjct: 148 GPPGLPGMKGDPG--EILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPP 205

Query: 452 GPPGPQG-----------LQGPKGEQGS------PGIPGM-----DGEQGLKGSKGDMGD 489
           GPPGP G            QGPKG++G       PG+PG       G+   KG KG  G+
Sbjct: 206 GPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGE 265

Query: 490 PGM-----TGEKGGIGLP---GLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHGPP 540
           PG       GEKG  G P   G PG +G KGEKG  G PG  G P +IG  GP G  G  
Sbjct: 266 PGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEA 325

Query: 541 GPMGPHGL---PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLD 597
           GP GP G+    GP G  G  G  G  GP+GE G KG  G PG  GP GLP   G+ G  
Sbjct: 326 GPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLP-VPGQAGAP 384

Query: 598 GFPGPRGEKGDLGEKGEKVTSPS 620
           GFPG RGEKGD G  G  +  PS
Sbjct: 385 GFPGERGEKGDRGFPGTSLPGPS 407



 Score =  144 bits (364), Expect = 2e-34
 Identities = 95/228 (41%), Positives = 105/228 (46%), Gaps = 20/228 (8%)

Query: 111  AREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG-PRMVFPK 169
            A E P     P G PG  G  G  G  G PG  G       KGDKG  G  G P +  PK
Sbjct: 1230 ATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGV------KGDKGNPGWPGAPGVPGPK 1283

Query: 170  INHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGK 229
             + GF      +     I G +G  GPPG PG  GP+G PG  G  G +G  GVPG  G 
Sbjct: 1284 GDPGF-QGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGL 1342

Query: 230  PGEQGLMGPL----GPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
            PG  G  GP     G PG  G  G PG+ G+ G  G  G  G  G  GIPGP G PG  G
Sbjct: 1343 PGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDG 1402

Query: 286  EKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGL 333
              G  GE GP G TG +G P        G PG  G PG  G PG P +
Sbjct: 1403 APGQKGEMGPAGPTGPRGFP--------GPPGPDGLPGSMGPPGTPSV 1442



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 38/104 (36%), Positives = 44/104 (42%), Gaps = 33/104 (31%)

Query: 121  PAGPPGKRG------KRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQGPRMVFPKIN 171
            P GPPG +G       +G++G +G  G PGP G PG     G KGE G  GP        
Sbjct: 1364 PEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP-------- 1415

Query: 172  HGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKD 215
                             G +G  GPPGP G PG  GPPG    D
Sbjct: 1416 ----------------TGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443


>gi|22027565 alpha 1 type XIII collagen isoform 1 [Homo sapiens]
          Length = 717

 Score =  412 bits (1058), Expect = e-115
 Identities = 277/724 (38%), Positives = 335/724 (46%), Gaps = 184/724 (25%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++ P+                   G  GQ G  G PG PGP G
Sbjct: 138 AIGMPGRVGSPGDAGLSIIGPR-------------------GPPGQPGTRGFPGFPGPIG 178

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQ----------------------- 244
             G  G  GP+G  G+ G PG+PG QG  G  G  G+                       
Sbjct: 179 LDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALK 238

Query: 245 ------------------------------KGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
                                         +G  G PG PG +G  G PGLPG +G  G+
Sbjct: 239 LLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGL 298

Query: 275 ---PGPKGEPGEQ---GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
              PGPKG+PG Q   G KG+ G  G  G  G KG PG + AG+KGEPG  G  G+KG  
Sbjct: 299 PGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAE 358

Query: 329 GLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGP 383
           G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+ G PG PG 
Sbjct: 359 GSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQVGPPGQPGD 416

Query: 384 KGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT 443
           KG++G +G +GP G KG +GE G             KG     E++DYNGN++EALQ I 
Sbjct: 417 KGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGNINEALQEIR 458

Query: 444 TLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE-- 495
           TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G   
Sbjct: 459 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPG 518

Query: 496 -------KGGIGLPGLPGANGMKGEKGDSGMPGPQG---------------PSIIGPPGP 533
                  KG  G PG PG  G KGE G +G PG +G               P   GPPGP
Sbjct: 519 KDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGP 578

Query: 534 PGPHGPPGPMGPHGL------------------------------PGPKGTDGPMGPHGP 563
           PG  G PGP G  GL                              PGP GT GP+G  GP
Sbjct: 579 PGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGP 638

Query: 564 AGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQ 621
           AGPKGERG KG  G  GP G  GLPG  G PG  G  G RG+KG  G KG+K    +P  
Sbjct: 639 AGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGL 698

Query: 622 HVPC 625
             PC
Sbjct: 699 DAPC 702



 Score =  156 bits (395), Expect = 5e-38
 Identities = 97/225 (43%), Positives = 116/225 (51%), Gaps = 37/225 (16%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 491 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 550

Query: 179 QQLIKRRLIKGDQGQAGPPGP-----PGPPGPRGPPGDTGKDGPRG---MPGVPGEPGKP 230
            +       KG+ G+ G PG      PGP GP GPPG  G  GP+G   + G  GE G  
Sbjct: 551 GE-------KGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQ 603

Query: 231 GEQGLMGPLG------------PPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP 275
           GE+G  GPLG            PPG  G IG PG  G  G+   KG+PG+ G  G  G+P
Sbjct: 604 GEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLP 663

Query: 276 ---GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
              GP G+ G +GE+G  G  GPKGD G++G PG  A    GE G
Sbjct: 664 GLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 708



 Score =  154 bits (390), Expect = 2e-37
 Identities = 109/283 (38%), Positives = 125/283 (44%), Gaps = 41/283 (14%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ G
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPG 166

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
            +G                        GP G  G  G  GPKG+ G  G PG  G QG K
Sbjct: 167 TRGFPGF-------------------PGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQK 207

Query: 482 GSKGDMGD----------PGMTGEKGGIGLPGLPGANGMKGE-----KGDSGMPGPQGPS 526
           G KG  G+          P        I L  LP  N ++       K  +        S
Sbjct: 208 GEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQAS 267

Query: 527 IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYG 586
           I GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G
Sbjct: 268 IQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPG 324

Query: 587 LPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           +PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 325 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 367



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 38/109 (34%), Positives = 44/109 (40%), Gaps = 32/109 (29%)

Query: 112 REAPSECNCPAGPPGKRGKRGRRGESGPPGQPGP---------QGPPGPKGDKGEQGDQG 162
           R  P     P G PG  G +G RG  G PG  GP          GPPG KG++GE+G +G
Sbjct: 623 RPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKG 682

Query: 163 PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG--PPGPPGPRGPP 209
            R                       KGD+G  G PG   P P G  G P
Sbjct: 683 SRGP---------------------KGDKGDQGAPGLDAPCPLGEDGLP 710


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  409 bits (1052), Expect = e-114
 Identities = 254/582 (43%), Positives = 288/582 (49%), Gaps = 100/582 (17%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGP-RMVFPKINHGFLSAD- 178
            P GP G RG RG  G+ GP G  G  GPPGP G++G QG QGP     PK   G    D 
Sbjct: 896  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG 955

Query: 179  -QQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGK-------- 229
                  +R   G QG+ GPPGP G  GP+GP G+TG  G RG PG PG PG+        
Sbjct: 956  LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG 1015

Query: 230  -------PGEQGLMGPLGP------PGQKGSIGAPGIPGMNGQKGEPGLPGAVGQ----- 271
                   PG QG+ G  GP      PG++G  GA G PG+ G +G  G PG VG      
Sbjct: 1016 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERG 1075

Query: 272  ----------NGIPGPKGEPGEQGEKGDAGENGPKGDTGE---------------KGDPG 306
                       G PGP+G PG  GEKG  GE GP+G  G                 G PG
Sbjct: 1076 SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1135

Query: 307  SSA-AGIKGEPGESGRPGQKGEPGLPGLPGL------PGIKGEPGFIGPQGEPGLPGLPG 359
                 G  GEPG+ G  G KGE G PG PGL      PGI G  G  GP+G+ G+ G  G
Sbjct: 1136 EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1195

Query: 360  TKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPG 418
             +G RG  GPPG  G +G PG PG KG+ G+ G  GP G  G RG +G +GA GP+GPPG
Sbjct: 1196 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1255

Query: 419  QKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQ 478
              G  G    +   G   EA          G PGPPG  G+ GPKGE+G  G  G  G  
Sbjct: 1256 SVGSVGG---VGEKGEPGEA----------GNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1302

Query: 479  GLKGSKGDMGDPGMTGEKGGIGLPGLP------------GANGMKGEKGDSGMPGPQGPS 526
            G  G+KG  GD G  G  G +G PG P            G  G KGE GD G PGP GPS
Sbjct: 1303 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1362

Query: 527  -IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585
               GPPGPPG  GPPG  G  G  G KG  G  G  GP G  G  G +G  G+PGP G  
Sbjct: 1363 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1422

Query: 586  GLPGKDGEPGL------DGFPGPRGE------KGDLGEKGEK 615
            G+PG  GE GL      DG PGP G       KGD G KGEK
Sbjct: 1423 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1464



 Score =  399 bits (1026), Expect = e-111
 Identities = 234/540 (43%), Positives = 272/540 (50%), Gaps = 115/540 (21%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E P     P G PG+RG  G  G  G PG+PGPQGPPGP G+KG  G++GP+        
Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ-------- 1110

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGE 232
                            G  G+ G  GP G PGP GP G  G+DG +G  G PG+ G  G+
Sbjct: 1111 ----------------GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD 1154

Query: 233  QGLMGPLGPPGQKGSIGAPGI------------PGMNGQKGE------PGLPGAVGQNGI 274
            +G  GP GPPG +G +GAPGI             GM GQKG+      PG PG +G  G+
Sbjct: 1155 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1214

Query: 275  PGPKGEPGEQGE---------KGDAGENGPKGDTGEKGDPGS----SAAGIKGEPGESGR 321
            PGP GE GE G+          G  G  GP G  G +G PGS       G KGEPGE+G 
Sbjct: 1215 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1274

Query: 322  P---------------GQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGE 366
            P               G+KGE G PG  G PG KG PG  GP+G PG  G PG  G  GE
Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334

Query: 367  AGPPG-------RGERGEPGAPGPKGKQGESGTRGP------------KGSKGDRGEKGD 407
             GP G       +GE G+PG PGP G  GE+G  GP            +G +G++G KG+
Sbjct: 1335 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394

Query: 408  SGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQG 467
            +GA+GP G  G  G QG                        G PGP G +G+ GP GEQG
Sbjct: 1395 AGAEGPPGKTGPVGPQGP----------------------AGKPGPEGLRGIPGPVGEQG 1432

Query: 468  SPGIPGMD---GEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG 524
             PG  G D   G  G  G  G  GDPG  GEKG  GL GL G  G +GEKGD G+PG QG
Sbjct: 1433 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1492

Query: 525  -PSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRG 583
             P   G  G PGP GP GP GP GLPGP+G  G  G  GPAG KG+ G  G  G PGP G
Sbjct: 1493 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  398 bits (1022), Expect = e-110
 Identities = 243/534 (45%), Positives = 273/534 (51%), Gaps = 56/534 (10%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E P     P G PG  G+ G +G+ G PG PG  G  GPKG  G  G       FP  N 
Sbjct: 825  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG-------FPGAN- 876

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGE 232
            G   A       R + G  G  G  GP GP G RG  G TGK GP+G  G  G PG PGE
Sbjct: 877  GEKGA-------RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 929

Query: 233  QGLMGPLGP---PGQKGSIGAP---GIPGMNGQKGEPGLPGAV---GQNGIPGPKGEPGE 283
            +G  GP GP   PG KG  G P   G+PG  GQ+GE G  G     G  G+ GP+G  GE
Sbjct: 930  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 989

Query: 284  QGEKGDAGENGPKGDTGEKGDPGSSA-AGIKGEPGESGRPGQKGEPGLPGLP---GLPGI 339
             G  G+ G  GP G  GE+G PG++   G KG+PG  G  G+ G  GL G P   GLPG 
Sbjct: 990  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1049

Query: 340  KGEPGF---IGPQGEPGLPGLPGTKGERGEAGP---PGR-GERGEPGAPGPKGKQGESGT 392
            +G PG     GPQG PG  G PG +G  G AGP   PGR G +G PG  G KG  GE G 
Sbjct: 1050 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1109

Query: 393  RGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPG 452
            +GP G  G +G  G  G  GP G PG+ GD+G        G+  +  +        GPPG
Sbjct: 1110 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE-------NGPPG 1162

Query: 453  PPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG 512
            PPG QG  G  G  G  G PG  G+QG+ G KGD G  G  G  G IGL GLPG  G KG
Sbjct: 1163 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1222

Query: 513  EKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP------------HGLPGPKGTDGPMGP 560
            E GD G  GP GP   GP GP GP+G  GP GP             G PG  G  GP G 
Sbjct: 1223 ENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1280

Query: 561  HGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
             G  GPKGERGEKG  G PG  GP G  G  G+ G  G PGP G  GD G  GE
Sbjct: 1281 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334



 Score =  397 bits (1021), Expect = e-110
 Identities = 245/615 (39%), Positives = 289/615 (46%), Gaps = 131/615 (21%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
            P G PG  G +G  G+ GP G  G QGPPGP G  G++G  G               D+ 
Sbjct: 554  PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 613

Query: 181  LIKRRLIKGDQGQAGPPGPPGPPGP----------------------------------- 205
                  + GD+G  G  GP GPPGP                                   
Sbjct: 614  FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 673

Query: 206  ----------RGPPGDTGKDGPRGMPGVPGEPGKPGEQGL---MGPLGPPGQKGSIGAPG 252
                       GPPG  G  GP+G PG PG+ G PG QGL    GP+GPPG+KG  G PG
Sbjct: 674  APGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG 733

Query: 253  IPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQ------------------------GEKG 288
            + G+ G  G PG PG  GQ+G  G  G PG Q                        GEKG
Sbjct: 734  LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 793

Query: 289  DAGENGPKGDTGEKGDPG----------------SSAAGIKGEPGESGRPGQKGEPGLPG 332
            + G  G KGD G KGD G                   AG  G+PG SG+ G+KG+ G+PG
Sbjct: 794  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853

Query: 333  LPGLPGIKGE------PGFIGPQGEPGLPGLPGTKGERGEAGPPG----RGERGEPGAPG 382
            LPG PG +G       PGF G  GE G  G+ G  G RG+ GP G    RG RG  G PG
Sbjct: 854  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 913

Query: 383  PKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRI 442
            PKG  G  G  GP G +G +G +G  G  GP+GPPG  G  G   +  + G   E     
Sbjct: 914  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG---LPGHPGQRGET---- 966

Query: 443  TTLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGL------KGSKGDMGDP 490
                 TGPP      GP GP G  GP GE+G PG PG  GEQGL      +G+KGD G  
Sbjct: 967  GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ 1026

Query: 491  GMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGP------------PGPHG 538
            G++G+ G  GL G PG  G+ G +G  G+ G +GP   GPPGP             GP G
Sbjct: 1027 GISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ--GPPGPVGSPGERGSAGTAGPIG 1084

Query: 539  PPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDG 598
             PG  GP G PGP G  G  G  GP GP G  G +G +G PGP GP G PG+DG+ G  G
Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1144

Query: 599  FPGPRGEKGDLGEKG 613
             PG +G KGD GE G
Sbjct: 1145 EPGQKGSKGDKGENG 1159



 Score =  393 bits (1009), Expect = e-109
 Identities = 240/549 (43%), Positives = 274/549 (49%), Gaps = 59/549 (10%)

Query: 112  REAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKIN 171
            R+ P       G PG  G++G RG +G PG  G +GP GP+G +G +G  G     PK  
Sbjct: 860  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG--KPGPKGT 917

Query: 172  HGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGE----- 226
             G               G++G  GP GP G PGP+GPPG  GKDG  G PG  GE     
Sbjct: 918  SGGDGPPGP-------PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 970

Query: 227  -PGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
              G PG  G++GP GP G+ G IG  G PG  G  GE GLPGA G+    G KG+PG QG
Sbjct: 971  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE---GAKGDPGPQG 1027

Query: 286  EKGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPG 344
              G  G  G +G  GE+G PG+  A G+KG  G  G PG  G PG  G  G  G  G PG
Sbjct: 1028 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1087

Query: 345  FIGPQGEPGLPGLPGTKGERGEAGPPGR----GERGEPGAPGPKGKQGESGTRGPKGSKG 400
              GPQG PG  G  G  GE+G  GP GR    G  G PG  GP G  GE G +G  G  G
Sbjct: 1088 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1147

Query: 401  DRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQR--------ITTLTVTGPPG 452
             +G KGD G  GP GPPG +G  GA  I   +G      Q+               GPPG
Sbjct: 1148 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1207

Query: 453  PPGPQGLQGPKGEQGS---------PGIPGMDGEQGLKGSKGDMGDPGMTGEKGGI---- 499
            P G QGL GP GE+G          PG PG  G QG  G+ G  G PG  G  GG+    
Sbjct: 1208 PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1267

Query: 500  --------GLPGLPGANGMKGEKGDSGMPGPQG----PSIIGPPGPPGPHGPPGPMGPHG 547
                    G PG  G  G KGE+G+ G  GP G    P   GPPG  GP G PGP+G  G
Sbjct: 1268 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1327

Query: 548  LPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGP---RGPYGLPGKDGEPGLDGFPGPRG 604
             PGP G  GP G  G  G KGE G+ G  G PGP    GP G PGK G PG  G  G +G
Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1387

Query: 605  EKGDLGEKG 613
            EKG  GE G
Sbjct: 1388 EKGAKGEAG 1396



 Score =  390 bits (1003), Expect = e-108
 Identities = 227/526 (43%), Positives = 276/526 (52%), Gaps = 43/526 (8%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGP--RMVFPKINHGFLSAD 178
           PAGP G  G  G +G +GPPG PG +GPPG  G  G  G  GP   M+     +G   + 
Sbjct: 458 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517

Query: 179 QQLIKRRLIKGD----QGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQG 234
              I  +  +      Q +    GPPGP G  G PG  G  G  G  G  G+PG  G +G
Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577

Query: 235 LMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENG 294
           + GP GP G+ G  G PG  G  G  GEPG  G  G +G+PG  G+ G +GE+G  G  G
Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 637

Query: 295 PKGDTGEKGDPGS-SAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEP---GFIGPQG 350
           P GD G +G+ G     G+ GE G  G  G +G PG PG PG+ G+ G P   G +GPQG
Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 697

Query: 351 EPGLPGLPGTKGERGEAGPPG----RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKG 406
           EPG PG  G  G +G  GP G     GE+G  G PG  G  G  G  G  G +G  GEKG
Sbjct: 698 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 757

Query: 407 DSGAQGPRGP---PGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPK 463
             G  GP+GP   PG +G +GA  +    G+  E  +        G PG  G  GL+G +
Sbjct: 758 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE-------DGFPGFKGDMGLKGDR 810

Query: 464 GEQGSPGIPGMDGEQGLKGSKGDMGDP---GMTGEKGGIGLPGLPGANGMKGEKGDSGMP 520
           GE G  G  G DG +G KG  G  GDP   G  GEKG +G+PGLPG  G +G KG +G P
Sbjct: 811 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870

Query: 521 GPQGPS-------IIGPPGPPGPHGPPGP------MGPHGLPGPKGTDGPMGPHGPAGPK 567
           G  G +       + G PGP G  GP GP       GP G PGPKGT G  GP GP G +
Sbjct: 871 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930

Query: 568 GERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
           G +G +G +G PGP+GP G PGKDG P   G PG RGE G  G+ G
Sbjct: 931 GPQGPQGPVGFPGPKGPPGPPGKDGLP---GHPGQRGETGFQGKTG 973



 Score =  341 bits (875), Expect = 1e-93
 Identities = 210/530 (39%), Positives = 255/530 (48%), Gaps = 92/530 (17%)

Query: 150 GPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG---PPGPPGPR 206
           G  G+KG++G+  P +V P +               L++G  G AGP G   PPG  GP 
Sbjct: 432 GAYGEKGQKGE--PAVVEPGM---------------LVEGPPGPAGPAGIMGPPGLQGPT 474

Query: 207 GPPGDTGKDGPRGMPGVPGEPGKPGEQGLM------------------------------ 236
           GPPGD G  GP G PG+PG  G PG  G M                              
Sbjct: 475 GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ 534

Query: 237 ---------GPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEK 287
                    GP+G  G+ G +G PG  G  G+ G+PG  G  G  G PGP G+PG++G  
Sbjct: 535 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 594

Query: 288 GDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIG 347
           G  G  G  G+ G KGD G    G+ G PG+ G  G++G  G PG PG  G++GE G IG
Sbjct: 595 GADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIG 652

Query: 348 PQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKG 406
           P+G PG  G  G  G RG  G PG+ G  G  G PGPKG  G  G  GP G +G+ G +G
Sbjct: 653 PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG 712

Query: 407 DSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQ 466
             G QGP GPPG+KG QG   +    G               GPPG PG +G  G KG  
Sbjct: 713 LPGPQGPIGPPGEKGPQGKPGLAGLPG-------------ADGPPGHPGKEGQSGEKGAL 759

Query: 467 GSPG------------IPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEK 514
           G PG            + G DG +GLKGSKG+ G+ G  G KG +GL G  G  G  G +
Sbjct: 760 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819

Query: 515 GDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKG 574
           G+ G  GP+G +  GP G PGP G  G  G  G+PG  G  G  GP G  G  G     G
Sbjct: 820 GEDGPEGPKGRA--GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF---PG 874

Query: 575 AMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTSPSQHVP 624
           A GE G RG  G PG  G+ G  G  G RG +G  G+ G K TS     P
Sbjct: 875 ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 924



 Score =  156 bits (394), Expect = 6e-38
 Identities = 91/220 (41%), Positives = 112/220 (50%), Gaps = 41/220 (18%)

Query: 121  PAGPPGKRG------------KRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFP 168
            P GPPGKRG            ++G +GE+G  G PG  GP GP+G  G+ G +G R +  
Sbjct: 1367 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1426

Query: 169  KINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPG 228
             +                 +G  G AG  GPPGP GP G P      G +G PG  GE G
Sbjct: 1427 PVGE---------------QGLPGAAGQDGPPGPMGPPGLP------GLKGDPGSKGEKG 1465

Query: 229  KPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKG 288
             PG  GL+GP G  G+KG  G PG  G  G KG+ G+PG  G  G PGP G PG QG KG
Sbjct: 1466 HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1525

Query: 289  DAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
            + G  GP    G+KGD     +G+ G PG  G PG+  +P
Sbjct: 1526 NKGSTGP---AGQKGD-----SGLPGPPGSPGPPGEVIQP 1557



 Score =  132 bits (331), Expect = 1e-30
 Identities = 76/184 (41%), Positives = 85/184 (46%), Gaps = 18/184 (9%)

Query: 103  EHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG 162
            E  AK     E P     P GP G  GK G  G  G PG  G QG PG  G  G  G  G
Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447

Query: 163  PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPG 222
            P    P +                +KGD G  G  G PG  G  GPPG+ G+ G RG+PG
Sbjct: 1448 P----PGLPG--------------LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489

Query: 223  VPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPG 282
              G PG  G+ G+ GP GP G  G  G PG  G  G KG  G  G  G +G+PGP G PG
Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549

Query: 283  EQGE 286
              GE
Sbjct: 1550 PPGE 1553


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  409 bits (1052), Expect = e-114
 Identities = 254/582 (43%), Positives = 288/582 (49%), Gaps = 100/582 (17%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGP-RMVFPKINHGFLSAD- 178
            P GP G RG RG  G+ GP G  G  GPPGP G++G QG QGP     PK   G    D 
Sbjct: 845  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG 904

Query: 179  -QQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGK-------- 229
                  +R   G QG+ GPPGP G  GP+GP G+TG  G RG PG PG PG+        
Sbjct: 905  LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG 964

Query: 230  -------PGEQGLMGPLGP------PGQKGSIGAPGIPGMNGQKGEPGLPGAVGQ----- 271
                   PG QG+ G  GP      PG++G  GA G PG+ G +G  G PG VG      
Sbjct: 965  KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERG 1024

Query: 272  ----------NGIPGPKGEPGEQGEKGDAGENGPKGDTGE---------------KGDPG 306
                       G PGP+G PG  GEKG  GE GP+G  G                 G PG
Sbjct: 1025 SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1084

Query: 307  SSA-AGIKGEPGESGRPGQKGEPGLPGLPGL------PGIKGEPGFIGPQGEPGLPGLPG 359
                 G  GEPG+ G  G KGE G PG PGL      PGI G  G  GP+G+ G+ G  G
Sbjct: 1085 EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144

Query: 360  TKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPG 418
             +G RG  GPPG  G +G PG PG KG+ G+ G  GP G  G RG +G +GA GP+GPPG
Sbjct: 1145 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1204

Query: 419  QKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQ 478
              G  G    +   G   EA          G PGPPG  G+ GPKGE+G  G  G  G  
Sbjct: 1205 SVGSVGG---VGEKGEPGEA----------GNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251

Query: 479  GLKGSKGDMGDPGMTGEKGGIGLPGLP------------GANGMKGEKGDSGMPGPQGPS 526
            G  G+KG  GD G  G  G +G PG P            G  G KGE GD G PGP GPS
Sbjct: 1252 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1311

Query: 527  -IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585
               GPPGPPG  GPPG  G  G  G KG  G  G  GP G  G  G +G  G+PGP G  
Sbjct: 1312 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1371

Query: 586  GLPGKDGEPGL------DGFPGPRGE------KGDLGEKGEK 615
            G+PG  GE GL      DG PGP G       KGD G KGEK
Sbjct: 1372 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1413



 Score =  399 bits (1026), Expect = e-111
 Identities = 234/540 (43%), Positives = 272/540 (50%), Gaps = 115/540 (21%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E P     P G PG+RG  G  G  G PG+PGPQGPPGP G+KG  G++GP+        
Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ-------- 1059

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGE 232
                            G  G+ G  GP G PGP GP G  G+DG +G  G PG+ G  G+
Sbjct: 1060 ----------------GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD 1103

Query: 233  QGLMGPLGPPGQKGSIGAPGI------------PGMNGQKGE------PGLPGAVGQNGI 274
            +G  GP GPPG +G +GAPGI             GM GQKG+      PG PG +G  G+
Sbjct: 1104 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1163

Query: 275  PGPKGEPGEQGE---------KGDAGENGPKGDTGEKGDPGS----SAAGIKGEPGESGR 321
            PGP GE GE G+          G  G  GP G  G +G PGS       G KGEPGE+G 
Sbjct: 1164 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1223

Query: 322  P---------------GQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGE 366
            P               G+KGE G PG  G PG KG PG  GP+G PG  G PG  G  GE
Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283

Query: 367  AGPPG-------RGERGEPGAPGPKGKQGESGTRGP------------KGSKGDRGEKGD 407
             GP G       +GE G+PG PGP G  GE+G  GP            +G +G++G KG+
Sbjct: 1284 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343

Query: 408  SGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQG 467
            +GA+GP G  G  G QG                        G PGP G +G+ GP GEQG
Sbjct: 1344 AGAEGPPGKTGPVGPQGP----------------------AGKPGPEGLRGIPGPVGEQG 1381

Query: 468  SPGIPGMD---GEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG 524
             PG  G D   G  G  G  G  GDPG  GEKG  GL GL G  G +GEKGD G+PG QG
Sbjct: 1382 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1441

Query: 525  -PSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRG 583
             P   G  G PGP GP GP GP GLPGP+G  G  G  GPAG KG+ G  G  G PGP G
Sbjct: 1442 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  398 bits (1022), Expect = e-110
 Identities = 243/534 (45%), Positives = 273/534 (51%), Gaps = 56/534 (10%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E P     P G PG  G+ G +G+ G PG PG  G  GPKG  G  G       FP  N 
Sbjct: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG-------FPGAN- 825

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGE 232
            G   A       R + G  G  G  GP GP G RG  G TGK GP+G  G  G PG PGE
Sbjct: 826  GEKGA-------RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 878

Query: 233  QGLMGPLGP---PGQKGSIGAP---GIPGMNGQKGEPGLPGAV---GQNGIPGPKGEPGE 283
            +G  GP GP   PG KG  G P   G+PG  GQ+GE G  G     G  G+ GP+G  GE
Sbjct: 879  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 938

Query: 284  QGEKGDAGENGPKGDTGEKGDPGSSA-AGIKGEPGESGRPGQKGEPGLPGLP---GLPGI 339
             G  G+ G  GP G  GE+G PG++   G KG+PG  G  G+ G  GL G P   GLPG 
Sbjct: 939  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 998

Query: 340  KGEPGF---IGPQGEPGLPGLPGTKGERGEAGP---PGR-GERGEPGAPGPKGKQGESGT 392
            +G PG     GPQG PG  G PG +G  G AGP   PGR G +G PG  G KG  GE G 
Sbjct: 999  QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1058

Query: 393  RGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPG 452
            +GP G  G +G  G  G  GP G PG+ GD+G        G+  +  +        GPPG
Sbjct: 1059 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE-------NGPPG 1111

Query: 453  PPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG 512
            PPG QG  G  G  G  G PG  G+QG+ G KGD G  G  G  G IGL GLPG  G KG
Sbjct: 1112 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1171

Query: 513  EKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP------------HGLPGPKGTDGPMGP 560
            E GD G  GP GP   GP GP GP+G  GP GP             G PG  G  GP G 
Sbjct: 1172 ENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229

Query: 561  HGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
             G  GPKGERGEKG  G PG  GP G  G  G+ G  G PGP G  GD G  GE
Sbjct: 1230 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283



 Score =  397 bits (1021), Expect = e-110
 Identities = 245/615 (39%), Positives = 289/615 (46%), Gaps = 131/615 (21%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
            P G PG  G +G  G+ GP G  G QGPPGP G  G++G  G               D+ 
Sbjct: 503  PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 562

Query: 181  LIKRRLIKGDQGQAGPPGPPGPPGP----------------------------------- 205
                  + GD+G  G  GP GPPGP                                   
Sbjct: 563  FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 622

Query: 206  ----------RGPPGDTGKDGPRGMPGVPGEPGKPGEQGL---MGPLGPPGQKGSIGAPG 252
                       GPPG  G  GP+G PG PG+ G PG QGL    GP+GPPG+KG  G PG
Sbjct: 623  APGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG 682

Query: 253  IPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQ------------------------GEKG 288
            + G+ G  G PG PG  GQ+G  G  G PG Q                        GEKG
Sbjct: 683  LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 742

Query: 289  DAGENGPKGDTGEKGDPG----------------SSAAGIKGEPGESGRPGQKGEPGLPG 332
            + G  G KGD G KGD G                   AG  G+PG SG+ G+KG+ G+PG
Sbjct: 743  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802

Query: 333  LPGLPGIKGE------PGFIGPQGEPGLPGLPGTKGERGEAGPPG----RGERGEPGAPG 382
            LPG PG +G       PGF G  GE G  G+ G  G RG+ GP G    RG RG  G PG
Sbjct: 803  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 862

Query: 383  PKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRI 442
            PKG  G  G  GP G +G +G +G  G  GP+GPPG  G  G   +  + G   E     
Sbjct: 863  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG---LPGHPGQRGET---- 915

Query: 443  TTLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGL------KGSKGDMGDP 490
                 TGPP      GP GP G  GP GE+G PG PG  GEQGL      +G+KGD G  
Sbjct: 916  GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ 975

Query: 491  GMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGP------------PGPHG 538
            G++G+ G  GL G PG  G+ G +G  G+ G +GP   GPPGP             GP G
Sbjct: 976  GISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ--GPPGPVGSPGERGSAGTAGPIG 1033

Query: 539  PPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDG 598
             PG  GP G PGP G  G  G  GP GP G  G +G +G PGP GP G PG+DG+ G  G
Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1093

Query: 599  FPGPRGEKGDLGEKG 613
             PG +G KGD GE G
Sbjct: 1094 EPGQKGSKGDKGENG 1108



 Score =  393 bits (1009), Expect = e-109
 Identities = 240/549 (43%), Positives = 274/549 (49%), Gaps = 59/549 (10%)

Query: 112  REAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKIN 171
            R+ P       G PG  G++G RG +G PG  G +GP GP+G +G +G  G     PK  
Sbjct: 809  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG--KPGPKGT 866

Query: 172  HGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGE----- 226
             G               G++G  GP GP G PGP+GPPG  GKDG  G PG  GE     
Sbjct: 867  SGGDGPPGP-------PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919

Query: 227  -PGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
              G PG  G++GP GP G+ G IG  G PG  G  GE GLPGA G+    G KG+PG QG
Sbjct: 920  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE---GAKGDPGPQG 976

Query: 286  EKGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPG 344
              G  G  G +G  GE+G PG+  A G+KG  G  G PG  G PG  G  G  G  G PG
Sbjct: 977  ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1036

Query: 345  FIGPQGEPGLPGLPGTKGERGEAGPPGR----GERGEPGAPGPKGKQGESGTRGPKGSKG 400
              GPQG PG  G  G  GE+G  GP GR    G  G PG  GP G  GE G +G  G  G
Sbjct: 1037 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1096

Query: 401  DRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQR--------ITTLTVTGPPG 452
             +G KGD G  GP GPPG +G  GA  I   +G      Q+               GPPG
Sbjct: 1097 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156

Query: 453  PPGPQGLQGPKGEQGS---------PGIPGMDGEQGLKGSKGDMGDPGMTGEKGGI---- 499
            P G QGL GP GE+G          PG PG  G QG  G+ G  G PG  G  GG+    
Sbjct: 1157 PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1216

Query: 500  --------GLPGLPGANGMKGEKGDSGMPGPQG----PSIIGPPGPPGPHGPPGPMGPHG 547
                    G PG  G  G KGE+G+ G  GP G    P   GPPG  GP G PGP+G  G
Sbjct: 1217 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1276

Query: 548  LPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGP---RGPYGLPGKDGEPGLDGFPGPRG 604
             PGP G  GP G  G  G KGE G+ G  G PGP    GP G PGK G PG  G  G +G
Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1336

Query: 605  EKGDLGEKG 613
            EKG  GE G
Sbjct: 1337 EKGAKGEAG 1345



 Score =  390 bits (1003), Expect = e-108
 Identities = 227/526 (43%), Positives = 276/526 (52%), Gaps = 43/526 (8%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGP--RMVFPKINHGFLSAD 178
           PAGP G  G  G +G +GPPG PG +GPPG  G  G  G  GP   M+     +G   + 
Sbjct: 407 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466

Query: 179 QQLIKRRLIKGD----QGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQG 234
              I  +  +      Q +    GPPGP G  G PG  G  G  G  G  G+PG  G +G
Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526

Query: 235 LMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENG 294
           + GP GP G+ G  G PG  G  G  GEPG  G  G +G+PG  G+ G +GE+G  G  G
Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586

Query: 295 PKGDTGEKGDPGS-SAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEP---GFIGPQG 350
           P GD G +G+ G     G+ GE G  G  G +G PG PG PG+ G+ G P   G +GPQG
Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 646

Query: 351 EPGLPGLPGTKGERGEAGPPG----RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKG 406
           EPG PG  G  G +G  GP G     GE+G  G PG  G  G  G  G  G +G  GEKG
Sbjct: 647 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706

Query: 407 DSGAQGPRGP---PGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPK 463
             G  GP+GP   PG +G +GA  +    G+  E  +        G PG  G  GL+G +
Sbjct: 707 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE-------DGFPGFKGDMGLKGDR 759

Query: 464 GEQGSPGIPGMDGEQGLKGSKGDMGDP---GMTGEKGGIGLPGLPGANGMKGEKGDSGMP 520
           GE G  G  G DG +G KG  G  GDP   G  GEKG +G+PGLPG  G +G KG +G P
Sbjct: 760 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819

Query: 521 GPQGPS-------IIGPPGPPGPHGPPGP------MGPHGLPGPKGTDGPMGPHGPAGPK 567
           G  G +       + G PGP G  GP GP       GP G PGPKGT G  GP GP G +
Sbjct: 820 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879

Query: 568 GERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
           G +G +G +G PGP+GP G PGKDG P   G PG RGE G  G+ G
Sbjct: 880 GPQGPQGPVGFPGPKGPPGPPGKDGLP---GHPGQRGETGFQGKTG 922



 Score =  341 bits (875), Expect = 1e-93
 Identities = 210/530 (39%), Positives = 255/530 (48%), Gaps = 92/530 (17%)

Query: 150 GPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG---PPGPPGPR 206
           G  G+KG++G+  P +V P +               L++G  G AGP G   PPG  GP 
Sbjct: 381 GAYGEKGQKGE--PAVVEPGM---------------LVEGPPGPAGPAGIMGPPGLQGPT 423

Query: 207 GPPGDTGKDGPRGMPGVPGEPGKPGEQGLM------------------------------ 236
           GPPGD G  GP G PG+PG  G PG  G M                              
Sbjct: 424 GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ 483

Query: 237 ---------GPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEK 287
                    GP+G  G+ G +G PG  G  G+ G+PG  G  G  G PGP G+PG++G  
Sbjct: 484 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 543

Query: 288 GDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIG 347
           G  G  G  G+ G KGD G    G+ G PG+ G  G++G  G PG PG  G++GE G IG
Sbjct: 544 GADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIG 601

Query: 348 PQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKG 406
           P+G PG  G  G  G RG  G PG+ G  G  G PGPKG  G  G  GP G +G+ G +G
Sbjct: 602 PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG 661

Query: 407 DSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQ 466
             G QGP GPPG+KG QG   +    G               GPPG PG +G  G KG  
Sbjct: 662 LPGPQGPIGPPGEKGPQGKPGLAGLPG-------------ADGPPGHPGKEGQSGEKGAL 708

Query: 467 GSPG------------IPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEK 514
           G PG            + G DG +GLKGSKG+ G+ G  G KG +GL G  G  G  G +
Sbjct: 709 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768

Query: 515 GDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKG 574
           G+ G  GP+G +  GP G PGP G  G  G  G+PG  G  G  GP G  G  G     G
Sbjct: 769 GEDGPEGPKGRA--GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF---PG 823

Query: 575 AMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTSPSQHVP 624
           A GE G RG  G PG  G+ G  G  G RG +G  G+ G K TS     P
Sbjct: 824 ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873



 Score =  156 bits (394), Expect = 6e-38
 Identities = 91/220 (41%), Positives = 112/220 (50%), Gaps = 41/220 (18%)

Query: 121  PAGPPGKRG------------KRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFP 168
            P GPPGKRG            ++G +GE+G  G PG  GP GP+G  G+ G +G R +  
Sbjct: 1316 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1375

Query: 169  KINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPG 228
             +                 +G  G AG  GPPGP GP G P      G +G PG  GE G
Sbjct: 1376 PVGE---------------QGLPGAAGQDGPPGPMGPPGLP------GLKGDPGSKGEKG 1414

Query: 229  KPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKG 288
             PG  GL+GP G  G+KG  G PG  G  G KG+ G+PG  G  G PGP G PG QG KG
Sbjct: 1415 HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1474

Query: 289  DAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
            + G  GP    G+KGD     +G+ G PG  G PG+  +P
Sbjct: 1475 NKGSTGP---AGQKGD-----SGLPGPPGSPGPPGEVIQP 1506



 Score =  132 bits (331), Expect = 1e-30
 Identities = 76/184 (41%), Positives = 85/184 (46%), Gaps = 18/184 (9%)

Query: 103  EHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG 162
            E  AK     E P     P GP G  GK G  G  G PG  G QG PG  G  G  G  G
Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396

Query: 163  PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPG 222
            P    P +                +KGD G  G  G PG  G  GPPG+ G+ G RG+PG
Sbjct: 1397 P----PGLPG--------------LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438

Query: 223  VPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPG 282
              G PG  G+ G+ GP GP G  G  G PG  G  G KG  G  G  G +G+PGP G PG
Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498

Query: 283  EQGE 286
              GE
Sbjct: 1499 PPGE 1502


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  409 bits (1052), Expect = e-114
 Identities = 254/582 (43%), Positives = 288/582 (49%), Gaps = 100/582 (17%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGP-RMVFPKINHGFLSAD- 178
            P GP G RG RG  G+ GP G  G  GPPGP G++G QG QGP     PK   G    D 
Sbjct: 884  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG 943

Query: 179  -QQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGK-------- 229
                  +R   G QG+ GPPGP G  GP+GP G+TG  G RG PG PG PG+        
Sbjct: 944  LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG 1003

Query: 230  -------PGEQGLMGPLGP------PGQKGSIGAPGIPGMNGQKGEPGLPGAVGQ----- 271
                   PG QG+ G  GP      PG++G  GA G PG+ G +G  G PG VG      
Sbjct: 1004 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERG 1063

Query: 272  ----------NGIPGPKGEPGEQGEKGDAGENGPKGDTGE---------------KGDPG 306
                       G PGP+G PG  GEKG  GE GP+G  G                 G PG
Sbjct: 1064 SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1123

Query: 307  SSA-AGIKGEPGESGRPGQKGEPGLPGLPGL------PGIKGEPGFIGPQGEPGLPGLPG 359
                 G  GEPG+ G  G KGE G PG PGL      PGI G  G  GP+G+ G+ G  G
Sbjct: 1124 EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183

Query: 360  TKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPG 418
             +G RG  GPPG  G +G PG PG KG+ G+ G  GP G  G RG +G +GA GP+GPPG
Sbjct: 1184 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1243

Query: 419  QKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQ 478
              G  G    +   G   EA          G PGPPG  G+ GPKGE+G  G  G  G  
Sbjct: 1244 SVGSVGG---VGEKGEPGEA----------GNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290

Query: 479  GLKGSKGDMGDPGMTGEKGGIGLPGLP------------GANGMKGEKGDSGMPGPQGPS 526
            G  G+KG  GD G  G  G +G PG P            G  G KGE GD G PGP GPS
Sbjct: 1291 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1350

Query: 527  -IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585
               GPPGPPG  GPPG  G  G  G KG  G  G  GP G  G  G +G  G+PGP G  
Sbjct: 1351 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1410

Query: 586  GLPGKDGEPGL------DGFPGPRGE------KGDLGEKGEK 615
            G+PG  GE GL      DG PGP G       KGD G KGEK
Sbjct: 1411 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1452



 Score =  399 bits (1026), Expect = e-111
 Identities = 234/540 (43%), Positives = 272/540 (50%), Gaps = 115/540 (21%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E P     P G PG+RG  G  G  G PG+PGPQGPPGP G+KG  G++GP+        
Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ-------- 1098

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGE 232
                            G  G+ G  GP G PGP GP G  G+DG +G  G PG+ G  G+
Sbjct: 1099 ----------------GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD 1142

Query: 233  QGLMGPLGPPGQKGSIGAPGI------------PGMNGQKGE------PGLPGAVGQNGI 274
            +G  GP GPPG +G +GAPGI             GM GQKG+      PG PG +G  G+
Sbjct: 1143 KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL 1202

Query: 275  PGPKGEPGEQGE---------KGDAGENGPKGDTGEKGDPGS----SAAGIKGEPGESGR 321
            PGP GE GE G+          G  G  GP G  G +G PGS       G KGEPGE+G 
Sbjct: 1203 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1262

Query: 322  P---------------GQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGE 366
            P               G+KGE G PG  G PG KG PG  GP+G PG  G PG  G  GE
Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322

Query: 367  AGPPG-------RGERGEPGAPGPKGKQGESGTRGP------------KGSKGDRGEKGD 407
             GP G       +GE G+PG PGP G  GE+G  GP            +G +G++G KG+
Sbjct: 1323 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382

Query: 408  SGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQG 467
            +GA+GP G  G  G QG                        G PGP G +G+ GP GEQG
Sbjct: 1383 AGAEGPPGKTGPVGPQGP----------------------AGKPGPEGLRGIPGPVGEQG 1420

Query: 468  SPGIPGMD---GEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG 524
             PG  G D   G  G  G  G  GDPG  GEKG  GL GL G  G +GEKGD G+PG QG
Sbjct: 1421 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1480

Query: 525  -PSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRG 583
             P   G  G PGP GP GP GP GLPGP+G  G  G  GPAG KG+ G  G  G PGP G
Sbjct: 1481 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  398 bits (1022), Expect = e-110
 Identities = 243/534 (45%), Positives = 273/534 (51%), Gaps = 56/534 (10%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E P     P G PG  G+ G +G+ G PG PG  G  GPKG  G  G       FP  N 
Sbjct: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG-------FPGAN- 864

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGE 232
            G   A       R + G  G  G  GP GP G RG  G TGK GP+G  G  G PG PGE
Sbjct: 865  GEKGA-------RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917

Query: 233  QGLMGPLGP---PGQKGSIGAP---GIPGMNGQKGEPGLPGAV---GQNGIPGPKGEPGE 283
            +G  GP GP   PG KG  G P   G+PG  GQ+GE G  G     G  G+ GP+G  GE
Sbjct: 918  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 977

Query: 284  QGEKGDAGENGPKGDTGEKGDPGSSA-AGIKGEPGESGRPGQKGEPGLPGLP---GLPGI 339
             G  G+ G  GP G  GE+G PG++   G KG+PG  G  G+ G  GL G P   GLPG 
Sbjct: 978  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1037

Query: 340  KGEPGF---IGPQGEPGLPGLPGTKGERGEAGP---PGR-GERGEPGAPGPKGKQGESGT 392
            +G PG     GPQG PG  G PG +G  G AGP   PGR G +G PG  G KG  GE G 
Sbjct: 1038 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1097

Query: 393  RGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPG 452
            +GP G  G +G  G  G  GP G PG+ GD+G        G+  +  +        GPPG
Sbjct: 1098 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE-------NGPPG 1150

Query: 453  PPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG 512
            PPG QG  G  G  G  G PG  G+QG+ G KGD G  G  G  G IGL GLPG  G KG
Sbjct: 1151 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1210

Query: 513  EKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP------------HGLPGPKGTDGPMGP 560
            E GD G  GP GP   GP GP GP+G  GP GP             G PG  G  GP G 
Sbjct: 1211 ENGDVGPMGPPGPP--GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268

Query: 561  HGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
             G  GPKGERGEKG  G PG  GP G  G  G+ G  G PGP G  GD G  GE
Sbjct: 1269 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322



 Score =  397 bits (1021), Expect = e-110
 Identities = 245/615 (39%), Positives = 289/615 (46%), Gaps = 131/615 (21%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
            P G PG  G +G  G+ GP G  G QGPPGP G  G++G  G               D+ 
Sbjct: 542  PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 601

Query: 181  LIKRRLIKGDQGQAGPPGPPGPPGP----------------------------------- 205
                  + GD+G  G  GP GPPGP                                   
Sbjct: 602  FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 661

Query: 206  ----------RGPPGDTGKDGPRGMPGVPGEPGKPGEQGL---MGPLGPPGQKGSIGAPG 252
                       GPPG  G  GP+G PG PG+ G PG QGL    GP+GPPG+KG  G PG
Sbjct: 662  APGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG 721

Query: 253  IPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQ------------------------GEKG 288
            + G+ G  G PG PG  GQ+G  G  G PG Q                        GEKG
Sbjct: 722  LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 781

Query: 289  DAGENGPKGDTGEKGDPG----------------SSAAGIKGEPGESGRPGQKGEPGLPG 332
            + G  G KGD G KGD G                   AG  G+PG SG+ G+KG+ G+PG
Sbjct: 782  EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841

Query: 333  LPGLPGIKGE------PGFIGPQGEPGLPGLPGTKGERGEAGPPG----RGERGEPGAPG 382
            LPG PG +G       PGF G  GE G  G+ G  G RG+ GP G    RG RG  G PG
Sbjct: 842  LPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPG 901

Query: 383  PKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRI 442
            PKG  G  G  GP G +G +G +G  G  GP+GPPG  G  G   +  + G   E     
Sbjct: 902  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG---LPGHPGQRGET---- 954

Query: 443  TTLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGL------KGSKGDMGDP 490
                 TGPP      GP GP G  GP GE+G PG PG  GEQGL      +G+KGD G  
Sbjct: 955  GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ 1014

Query: 491  GMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGP------------PGPHG 538
            G++G+ G  GL G PG  G+ G +G  G+ G +GP   GPPGP             GP G
Sbjct: 1015 GISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ--GPPGPVGSPGERGSAGTAGPIG 1072

Query: 539  PPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDG 598
             PG  GP G PGP G  G  G  GP GP G  G +G +G PGP GP G PG+DG+ G  G
Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1132

Query: 599  FPGPRGEKGDLGEKG 613
             PG +G KGD GE G
Sbjct: 1133 EPGQKGSKGDKGENG 1147



 Score =  393 bits (1009), Expect = e-109
 Identities = 240/549 (43%), Positives = 274/549 (49%), Gaps = 59/549 (10%)

Query: 112  REAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKIN 171
            R+ P       G PG  G++G RG +G PG  G +GP GP+G +G +G  G     PK  
Sbjct: 848  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG--KPGPKGT 905

Query: 172  HGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGE----- 226
             G               G++G  GP GP G PGP+GPPG  GKDG  G PG  GE     
Sbjct: 906  SGGDGPPGP-------PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 958

Query: 227  -PGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
              G PG  G++GP GP G+ G IG  G PG  G  GE GLPGA G+    G KG+PG QG
Sbjct: 959  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE---GAKGDPGPQG 1015

Query: 286  EKGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPG 344
              G  G  G +G  GE+G PG+  A G+KG  G  G PG  G PG  G  G  G  G PG
Sbjct: 1016 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1075

Query: 345  FIGPQGEPGLPGLPGTKGERGEAGPPGR----GERGEPGAPGPKGKQGESGTRGPKGSKG 400
              GPQG PG  G  G  GE+G  GP GR    G  G PG  GP G  GE G +G  G  G
Sbjct: 1076 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1135

Query: 401  DRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQR--------ITTLTVTGPPG 452
             +G KGD G  GP GPPG +G  GA  I   +G      Q+               GPPG
Sbjct: 1136 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195

Query: 453  PPGPQGLQGPKGEQGS---------PGIPGMDGEQGLKGSKGDMGDPGMTGEKGGI---- 499
            P G QGL GP GE+G          PG PG  G QG  G+ G  G PG  G  GG+    
Sbjct: 1196 PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1255

Query: 500  --------GLPGLPGANGMKGEKGDSGMPGPQG----PSIIGPPGPPGPHGPPGPMGPHG 547
                    G PG  G  G KGE+G+ G  GP G    P   GPPG  GP G PGP+G  G
Sbjct: 1256 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1315

Query: 548  LPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGP---RGPYGLPGKDGEPGLDGFPGPRG 604
             PGP G  GP G  G  G KGE G+ G  G PGP    GP G PGK G PG  G  G +G
Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1375

Query: 605  EKGDLGEKG 613
            EKG  GE G
Sbjct: 1376 EKGAKGEAG 1384



 Score =  390 bits (1003), Expect = e-108
 Identities = 227/526 (43%), Positives = 276/526 (52%), Gaps = 43/526 (8%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGP--RMVFPKINHGFLSAD 178
           PAGP G  G  G +G +GPPG PG +GPPG  G  G  G  GP   M+     +G   + 
Sbjct: 446 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505

Query: 179 QQLIKRRLIKGD----QGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQG 234
              I  +  +      Q +    GPPGP G  G PG  G  G  G  G  G+PG  G +G
Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565

Query: 235 LMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENG 294
           + GP GP G+ G  G PG  G  G  GEPG  G  G +G+PG  G+ G +GE+G  G  G
Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625

Query: 295 PKGDTGEKGDPGS-SAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEP---GFIGPQG 350
           P GD G +G+ G     G+ GE G  G  G +G PG PG PG+ G+ G P   G +GPQG
Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685

Query: 351 EPGLPGLPGTKGERGEAGPPG----RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKG 406
           EPG PG  G  G +G  GP G     GE+G  G PG  G  G  G  G  G +G  GEKG
Sbjct: 686 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745

Query: 407 DSGAQGPRGP---PGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPK 463
             G  GP+GP   PG +G +GA  +    G+  E  +        G PG  G  GL+G +
Sbjct: 746 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE-------DGFPGFKGDMGLKGDR 798

Query: 464 GEQGSPGIPGMDGEQGLKGSKGDMGDP---GMTGEKGGIGLPGLPGANGMKGEKGDSGMP 520
           GE G  G  G DG +G KG  G  GDP   G  GEKG +G+PGLPG  G +G KG +G P
Sbjct: 799 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858

Query: 521 GPQGPS-------IIGPPGPPGPHGPPGP------MGPHGLPGPKGTDGPMGPHGPAGPK 567
           G  G +       + G PGP G  GP GP       GP G PGPKGT G  GP GP G +
Sbjct: 859 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918

Query: 568 GERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
           G +G +G +G PGP+GP G PGKDG P   G PG RGE G  G+ G
Sbjct: 919 GPQGPQGPVGFPGPKGPPGPPGKDGLP---GHPGQRGETGFQGKTG 961



 Score =  341 bits (875), Expect = 1e-93
 Identities = 210/530 (39%), Positives = 255/530 (48%), Gaps = 92/530 (17%)

Query: 150 GPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG---PPGPPGPR 206
           G  G+KG++G+  P +V P +               L++G  G AGP G   PPG  GP 
Sbjct: 420 GAYGEKGQKGE--PAVVEPGM---------------LVEGPPGPAGPAGIMGPPGLQGPT 462

Query: 207 GPPGDTGKDGPRGMPGVPGEPGKPGEQGLM------------------------------ 236
           GPPGD G  GP G PG+PG  G PG  G M                              
Sbjct: 463 GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ 522

Query: 237 ---------GPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEK 287
                    GP+G  G+ G +G PG  G  G+ G+PG  G  G  G PGP G+PG++G  
Sbjct: 523 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRP 582

Query: 288 GDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIG 347
           G  G  G  G+ G KGD G    G+ G PG+ G  G++G  G PG PG  G++GE G IG
Sbjct: 583 GADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIG 640

Query: 348 PQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKG 406
           P+G PG  G  G  G RG  G PG+ G  G  G PGPKG  G  G  GP G +G+ G +G
Sbjct: 641 PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG 700

Query: 407 DSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQ 466
             G QGP GPPG+KG QG   +    G               GPPG PG +G  G KG  
Sbjct: 701 LPGPQGPIGPPGEKGPQGKPGLAGLPG-------------ADGPPGHPGKEGQSGEKGAL 747

Query: 467 GSPG------------IPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEK 514
           G PG            + G DG +GLKGSKG+ G+ G  G KG +GL G  G  G  G +
Sbjct: 748 GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807

Query: 515 GDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKG 574
           G+ G  GP+G +  GP G PGP G  G  G  G+PG  G  G  GP G  G  G     G
Sbjct: 808 GEDGPEGPKGRA--GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF---PG 862

Query: 575 AMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTSPSQHVP 624
           A GE G RG  G PG  G+ G  G  G RG +G  G+ G K TS     P
Sbjct: 863 ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 912



 Score =  156 bits (394), Expect = 6e-38
 Identities = 91/220 (41%), Positives = 112/220 (50%), Gaps = 41/220 (18%)

Query: 121  PAGPPGKRG------------KRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFP 168
            P GPPGKRG            ++G +GE+G  G PG  GP GP+G  G+ G +G R +  
Sbjct: 1355 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1414

Query: 169  KINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPG 228
             +                 +G  G AG  GPPGP GP G P      G +G PG  GE G
Sbjct: 1415 PVGE---------------QGLPGAAGQDGPPGPMGPPGLP------GLKGDPGSKGEKG 1453

Query: 229  KPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKG 288
             PG  GL+GP G  G+KG  G PG  G  G KG+ G+PG  G  G PGP G PG QG KG
Sbjct: 1454 HPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG 1513

Query: 289  DAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
            + G  GP    G+KGD     +G+ G PG  G PG+  +P
Sbjct: 1514 NKGSTGP---AGQKGD-----SGLPGPPGSPGPPGEVIQP 1545



 Score =  132 bits (331), Expect = 1e-30
 Identities = 76/184 (41%), Positives = 85/184 (46%), Gaps = 18/184 (9%)

Query: 103  EHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG 162
            E  AK     E P     P GP G  GK G  G  G PG  G QG PG  G  G  G  G
Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435

Query: 163  PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPG 222
            P    P +                +KGD G  G  G PG  G  GPPG+ G+ G RG+PG
Sbjct: 1436 P----PGLPG--------------LKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477

Query: 223  VPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPG 282
              G PG  G+ G+ GP GP G  G  G PG  G  G KG  G  G  G +G+PGP G PG
Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537

Query: 283  EQGE 286
              GE
Sbjct: 1538 PPGE 1541


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  409 bits (1050), Expect = e-114
 Identities = 246/558 (44%), Positives = 284/558 (50%), Gaps = 86/558 (15%)

Query: 112 REAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKIN 171
           R AP E   P G PG  G RG  G  G  GQPGP GPPG  G  G  G +G   V P  +
Sbjct: 302 RGAPGERGRP-GLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGE--VGPAGS 358

Query: 172 HGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG------ 225
            G   A  Q    R   G QG AG  GPPGPPG  G PG  G+ GP G+PG PG      
Sbjct: 359 PGSNGAPGQ----RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414

Query: 226 ---------------EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVG 270
                            G+PG+ G  G  GP G++G  G PG+PG  G+ G+ G PG  G
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG 474

Query: 271 QNGIPGPKGEPGEQGEKGDAGENG---PKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKG 326
            NG+PG  GE G  G +G AG NG    KG  GE+G PG +   G  GEPG  G PG  G
Sbjct: 475 ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG 534

Query: 327 EPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKG 385
             G+PG PG PG  G+PG  G QGE G PG PG  G RG+ G  G  G +G  GAPG  G
Sbjct: 535 MRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594

Query: 386 KQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTL 445
           ++G  G  GP+G  G  GE G  G  GP GP G KGD                       
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGD----------------------- 631

Query: 446 TVTGPPGPPGPQGLQG---PKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLP 502
             TGPPGP G QGL G   P GE G PG PG  G+ G  G+ G  GD G  GE+G  GL 
Sbjct: 632 --TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLA 689

Query: 503 GLPGANG------MKGEKGDSGMPGPQG----PSI---------IGPPGPPGPHGPPGPM 543
           G PG  G       +G KG +G PGP G    P +         +G PGP G  G PG  
Sbjct: 690 GAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGP 749

Query: 544 GPHGLPG---PKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGE---PGLD 597
           G  G+PG   P+G  GP+GP GPAG  G++GE GA G PG  GP G PG+ GE   PG  
Sbjct: 750 GADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA 809

Query: 598 GFPGPRGEKGDLGEKGEK 615
           GFPG  G+ G+ G KGE+
Sbjct: 810 GFPGAPGQNGEPGGKGER 827



 Score =  400 bits (1028), Expect = e-111
 Identities = 246/565 (43%), Positives = 280/565 (49%), Gaps = 74/565 (13%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
            GP G  G  G+ GE G PG PGPQGPPG  G+ G QG  GP               Q L 
Sbjct: 582  GPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQ 641

Query: 183  KRRLIKGDQGQAGPPGPPGPPGPRGPPG------DTGKDGPRGMPGVPGEPG------KP 230
                  G  G+ G PG PGP G  G PG      D G  G RG PG+ G PG       P
Sbjct: 642  GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701

Query: 231  GEQGLMGPLGPPGQKGSIGAPGI------------PGMNGQKGEPGLPGAVGQNGIPGPK 278
            G +G  G  GPPG  G+ G PG+            PG  G KGEPG PGA G  G  GP+
Sbjct: 702  GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPR 761

Query: 279  GEPGEQGEKGDAGENGPKGDTGEKGDPG-SSAAGIKGEPGESGRPGQKGEPGLPGLPGLP 337
            G  G  G  G AG+ G KG+ G  G PG +   G  GE GE+G PG  G PG PG  G P
Sbjct: 762  GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEP 821

Query: 338  GIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPG----RGERGEPGAPGPKGKQGESGTR 393
            G KGE G  G +GE G PG+ G  G  G AGPPG    +GERG PG PG  G  G  G  
Sbjct: 822  GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP 881

Query: 394  GPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQR------------ 441
            GP GS G+ G  G SG+ G  GPPG  G+ GA      +G   +A Q             
Sbjct: 882  GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPP 941

Query: 442  -------ITTLT----VTGPPGPPGPQGLQGP---KGEQGSPGIPGMDGE------QGLK 481
                   I  +T    + GPPG PGP+G  GP   KGE G PG  G+ GE      QGL 
Sbjct: 942  GAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP 1001

Query: 482  GSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPG-PQGPSIIGPPGPPGP---- 536
            G  G  G+PG  G  G  GLPG  G+ G KG++G++G PG P  P   GPPGP GP    
Sbjct: 1002 GLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKS 1061

Query: 537  --HGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEP 594
               G  GP GP G PGP G+ G  GP GP G KGE GE+GA G  G RG  G PG  G P
Sbjct: 1062 GDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP 1121

Query: 595  ------GLDGFPGPRGEKGDLGEKG 613
                  G  G PGP G +G +G  G
Sbjct: 1122 GPAGQQGAIGSPGPAGPRGPVGPSG 1146



 Score =  399 bits (1024), Expect = e-111
 Identities = 239/571 (41%), Positives = 272/571 (47%), Gaps = 111/571 (19%)

Query: 115 PSEC-NCPAGPPGKR---------------GKRGRRGESGPPGQPGPQGPPGPKGDKGEQ 158
           P  C +CP GP                   G  G  G +GPPG PGP G  G  G  G  
Sbjct: 138 PGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSP 197

Query: 159 GDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPR 218
           G QGP                         G+ GQAGP GPPGPPG  GP G  GKDG  
Sbjct: 198 GYQGP------------------------PGEPGQAGPSGPPGPPGAIGPSGPAGKDGES 233

Query: 219 GMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIP--- 275
           G PG PGE G PG  G+ GP G PG  G  G  G  G NG+KGE G PG  G+NG+P   
Sbjct: 234 GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN 293

Query: 276 ------GPKGEPGEQGE---------------KGDAGENGPKGDTGEKGDPGSSAA---- 310
                 GP+G PGE+G                +G  G+ GP G  G  G PGS  A    
Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 311 GIKGEPGESGRPGQKGEP------GLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGER 364
           G  G PG +G PGQ+GEP      G  G PG PGI G PG  G  G  G+PG PG  G R
Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413

Query: 365 GEAGPPG-------RGERGEP------GAPGPKGKQGESGTRGPKGSKGDRGEKGD---- 407
           G  GP G       RG  GEP      G PGP+G++GE+G  G  G+KG+ G+ G     
Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473

Query: 408 -----SGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGP 462
                 GA G RG PG +G  G   I    G   E           G PGP GP+G  G 
Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGE----------RGAPGPAGPRGAAGE 523

Query: 463 KGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGP 522
            G  G PG PGM G  G  G  G  G PG  G +G  G PG PG +G +G+ G  G PGP
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGP 583

Query: 523 QGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPR 582
           +G    G PG  G  G PG  GP G PG  G  GP GP GP GP G++G+    G PGP+
Sbjct: 584 KGND--GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGD---TGPPGPQ 638

Query: 583 GPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
           G  GLPG  G PG +G PG  G KGD G  G
Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPKGDAGAPG 669



 Score =  396 bits (1017), Expect = e-110
 Identities = 239/553 (43%), Positives = 274/553 (49%), Gaps = 90/553 (16%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
            GP G RG  G  G  G PG PG +G PG  G  G  G  GP                   
Sbjct: 513  GPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP------------------- 553

Query: 183  KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPP 242
                  G QG++G PGPPGP GPRG PG  G  GP+G  G PG+ G+ G  G  GP GPP
Sbjct: 554  -----PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608

Query: 243  GQKGSIGAPGIPGMNG---QKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDT 299
            G+ G  G  G PG  G    KG+ G PG  G  G+PG  G PGE G+ G   E GPKGD 
Sbjct: 609  GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPG---EPGPKGDA 665

Query: 300  GEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGL---PG 356
            G  G PG    G  G PGE G PG  G PGL G  G PG +G  G  GP G PG    PG
Sbjct: 666  GAPGAPGGK--GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPG 723

Query: 357  LPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGS------KGDRGEKGDSG 409
            L G  GERG  G PG +G++GEPG PG  G  G+ G RGP G        G  G+KG+ G
Sbjct: 724  LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGG 783

Query: 410  AQG------PRGPPGQKGDQGATEIIDY------NGNLHEALQRITTLT--------VTG 449
            A G      PRG PG++G+ G      +      NG      +R             V G
Sbjct: 784  APGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAG 843

Query: 450  PPG------PPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGG----- 498
            PPG      PPGPQG++G +G  G PG  G  G +GL G  G  G+PG  G  G      
Sbjct: 844  PPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG 903

Query: 499  ----IGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHGPPGPMGPHGLPGPKG 553
                 G  G PG+ G+ G KGD+G PG +G P   GPPG PGP G  G  G  GL GP G
Sbjct: 904  PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPG 963

Query: 554  TDGPMGPHGPAGPKGERGEKGA---MGEPGPRGPYGLPG---------KDGEPGLDGFPG 601
              GP G  GP G KGE G+ GA    GE GP GP GLPG         +DG PG DG PG
Sbjct: 964  MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023

Query: 602  PRGEKGDLGEKGE 614
              G  G  G++GE
Sbjct: 1024 RDGSPGGKGDRGE 1036



 Score =  394 bits (1013), Expect = e-109
 Identities = 233/563 (41%), Positives = 273/563 (48%), Gaps = 60/563 (10%)

Query: 115 PSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF 174
           P     P  PP  +G +G +G+ GPPG PG  G PG  G  G  G  GP  +      G 
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148

Query: 175 LSADQQL----IKRRL----IKGDQGQAGPPGPPGPPGP------------RGPPGDTGK 214
            +   Q     +K  +    + G  G AGPPGPPGPPG             +GPPG+ G+
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 215 DGPRGMPGVPG------------EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGE 262
            GP G PG PG            E G+PG  G  G  GPPG KG  G PG PGM G +G 
Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGF 268

Query: 263 PGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPG-SSAAGIKGEPGESGR 321
            G  G  G+ G PG KGE G  GE G  G  GP+G  GE+G PG   AAG +G  G  G 
Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328

Query: 322 PGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGE---------RGEAGPPG- 371
            GQ G PG PG  G PG  G  G +GP G PG  G PG +GE         +G  GPPG 
Sbjct: 329 DGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388

Query: 372 ---------RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGD 422
                     G  G PGAPG  G +G  G  G  G+ G RG  G+ G  G +G PG +G+
Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448

Query: 423 QGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKG 482
           +G   I    G   E  +        G PG PG  GL G  GE+G+PG  G  G  G+ G
Sbjct: 449 RGEAGIPGVPGAKGEDGK-------DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPG 501

Query: 483 SKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPG-PQGPSIIGPPGPPGPHGPPG 541
            KG  G+ G  G  G  G  G PG +G+ G  G  GMPG P GP   G PGPPG  G  G
Sbjct: 502 EKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561

Query: 542 PMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPG 601
             GP G  GP+G  G MG  GP G  G  G+ G  G PG  GP G PGK+GE G  G PG
Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG 621

Query: 602 PRGEKGDLGEKGEKVTSPSQHVP 624
           P G  GD G+ G       Q +P
Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLP 644



 Score =  391 bits (1005), Expect = e-109
 Identities = 236/559 (42%), Positives = 281/559 (50%), Gaps = 97/559 (17%)

Query: 122 AGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQL 181
           AG PG  G +G  G+ G PG+PG  G PG  G++G  G +GP                  
Sbjct: 452 AGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPA----------------- 494

Query: 182 IKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGP 241
                I G++G AG  G PGP GPRG  G+ G+DG  G PG+ G PG PG  G  G  GP
Sbjct: 495 -GPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553

Query: 242 PGQKGSIGAPGIPGMNGQKGEPGL---------PGAVGQNGI------PGPKGEPGEQGE 286
           PG +G  G PG PG +G +G+PG+          GA G+NG       PGP+G PG+ GE
Sbjct: 554 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613

Query: 287 KGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPG------LPGLPGI 339
            G  G  GP G  G+KGD G     G++G PG  G PG+ G+PG PG       PG PG 
Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673

Query: 340 KGEPGFIGPQGEPGL---PGL------PGTKGERGEAGPPGR-------------GERGE 377
           KG+ G  G +G PGL   PGL      PG +G +G AGPPG              GERG 
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733

Query: 378 PGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHE 437
            G+PGPKG +GE G  G  G  G  G +G +G  GP GP GQ GD+G        G    
Sbjct: 734 LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG---- 789

Query: 438 ALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGS------KGDMGDPG 491
                    + GP G PG +G  GP G  G PG PG +GE G KG       KG+ G PG
Sbjct: 790 ---------IAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840

Query: 492 MTGEKGGIGLPGLPGANGMKGEKGDSG------------MPGPQGPS-IIGPPGPPGPHG 538
           + G  GG G  G PG  G+KGE+G  G            +PGP G +   GPPGP G  G
Sbjct: 841 VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPG 900

Query: 539 PPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGL-- 596
             GP GP G  G  G+ G  GP G AG  GE+G  GA G PG  GP G+ G  G  GL  
Sbjct: 901 KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAG 960

Query: 597 -DGFPGPRGEKGDLGEKGE 614
             G PGPRG  G  G KGE
Sbjct: 961 PPGMPGPRGSPGPQGVKGE 979



 Score =  328 bits (841), Expect = 9e-90
 Identities = 197/469 (42%), Positives = 232/469 (49%), Gaps = 68/469 (14%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQG----PRMVFPKINHGFLS 176
            P G PG+RG+ G  G +G PG PG  G PG KG++G  G++G    P +  P        
Sbjct: 793  PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP-------- 844

Query: 177  ADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGK---DGPRGMPGVP---GEPGKP 230
                        G  G AGPPGP G  G RG PG  G     G RG+PG P   G PG P
Sbjct: 845  -----------PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893

Query: 231  GEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDA 290
            G  G  G  GPPG  G+ GAPG PG++G KG+ G PG  G  G  GP G PG  G  G  
Sbjct: 894  GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT 953

Query: 291  GEN---GPKGDTGEKGDPG-SSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFI 346
            G     GP G  G +G PG     G  G+PG +G  G++G PG  GLPGL G  GEPG  
Sbjct: 954  GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD 1013

Query: 347  GPQGEPGLP---GLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDR 402
            G  G  GLP   G PG KG+RGE G PG  G  G PG PGP G  G+SG RG  G  G  
Sbjct: 1014 GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA 1073

Query: 403  GEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGP 462
            G  G +G++G  GP G +GD+G T                            G +G  G 
Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGET----------------------------GERGAAGI 1105

Query: 463  KGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGP 522
            KG +G PG PG  G  G  G +G +G PG  G +G +G  G PG +G  G  G  G PGP
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP 1165

Query: 523  QG-PSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGER 570
            +G     G  G PG  G PGP GP G PGP    G +G    AG  GE+
Sbjct: 1166 RGNRGERGSEGSPGHPGQPGPPGPPGAPGP--CCGGVGAAAIAGIGGEK 1212



 Score =  317 bits (811), Expect = 3e-86
 Identities = 190/450 (42%), Positives = 225/450 (50%), Gaps = 62/450 (13%)

Query: 114  APSECNCPAGPPGKRGKRGRRGESGPP------GQPGPQGPPGPKGDKGEQGDQGPRMVF 167
            AP +   P G  G+RG  G +GE GPP      G  GP GPPGP+G KGE+G  G     
Sbjct: 814  APGQNGEPGGK-GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGA- 871

Query: 168  PKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEP 227
                 GF              G +G  GPPG  G PGP GP G  GKDGP G  G  G P
Sbjct: 872  ----AGF-------------PGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914

Query: 228  GKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGA---VGQNGIPGPKGEPGEQ 284
            G PG  G  G  G PG+KGS GA G PG  G  G  G+ GA    G  G+PGP+G PG Q
Sbjct: 915  GSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQ 974

Query: 285  GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPG 344
            G KG++G+ G  G +GE+G PG    G+ G  G +G PG+ G PG  GLPG  G  G  G
Sbjct: 975  GVKGESGKPGANGLSGERGPPGPQ--GLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKG 1032

Query: 345  FIGPQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRG 403
              G  G PG PG PG  G  G  GP G+ G+RGE G  GP G  G +G+RG  G +G RG
Sbjct: 1033 DRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRG 1092

Query: 404  EKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPK 463
            +KG++G +G  G  G +G                             PG PG  G  GP 
Sbjct: 1093 DKGETGERGAAGIKGHRGF----------------------------PGNPGAPGSPGPA 1124

Query: 464  GEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQ 523
            G+QG+ G PG  G +G  G  G  G  G +G  G IG PG  G  G +G +G  G PG  
Sbjct: 1125 GQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184

Query: 524  GPSIIGPPGPPGP-HGPPGPMGPHGLPGPK 552
            GP   GPPG PGP  G  G     G+ G K
Sbjct: 1185 GPP--GPPGAPGPCCGGVGAAAIAGIGGEK 1212



 Score =  142 bits (359), Expect = 7e-34
 Identities = 100/287 (34%), Positives = 116/287 (40%), Gaps = 50/287 (17%)

Query: 377 EPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPR---GPPGQKGDQGATEIIDYNG 433
           E   P P+   GE     P+            G QGP+   GPPG  G  G   I    G
Sbjct: 71  ELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG 130

Query: 434 N----------------------LHEALQRITTLTV---------TGPPGPPGPQGLQGP 462
           +                       +++    + + V          GPPGPPGP G  G 
Sbjct: 131 SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGH 190

Query: 463 KGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGP 522
            G  GSPG  G  GE G  G  G  G PG  G  G  G  G  G  G  GE+G  G PG 
Sbjct: 191 PGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGI 250

Query: 523 QGPSII-------------GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGE 569
           +GP+ I             G  G  G  G PG  G +GLPG  G  GPMGP G  G +G 
Sbjct: 251 KGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGR 310

Query: 570 ---RGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
               G  GA G  G RG  G PG  G PG  GFPG  G KG++G  G
Sbjct: 311 PGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAG 357



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 35/117 (29%)

Query: 110  IAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPK 169
            I    P+    P GP G  GK G  G  GP G       PGP+G++GE+G +G       
Sbjct: 1130 IGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP------PGPRGNRGERGSEGS------ 1177

Query: 170  INHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGE 226
                               G  GQ GPPGPPG PGP       G  G   + G+ GE
Sbjct: 1178 ------------------PGHPGQPGPPGPPGAPGP-----CCGGVGAAAIAGIGGE 1211


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  408 bits (1048), Expect = e-114
 Identities = 245/546 (44%), Positives = 281/546 (51%), Gaps = 62/546 (11%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF--LSADQQ 180
           G  G  G RGR GE G PG PGP GPPGP G  G  G+   +M       GF   +   Q
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA-----GGFDEKAGGAQ 195

Query: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRG---------PPGDTGKDGPRGMPGVPG------ 225
           L   +   G  G  GPPGP G PGP+G          PG +G  GPRG PG PG      
Sbjct: 196 LGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG 255

Query: 226 EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
           E GKPG+ G  GP GP G +G  G PG+PG+ G +G PGL GA G+ G PG KGE G  G
Sbjct: 256 EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 315

Query: 286 EKGDAGENGPKGDTGEKGDPG----SSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKG 341
           E G  G  GP+G  GE+G  G    + A G  G+PG +G PG  G  G PG PG PG KG
Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 375

Query: 342 E---------PGFIGPQGEPGLPGLP------------GTKGERGEAGPPG-RGERGEPG 379
           E          G  GP+GEPG PG P            G  G +G AG PG  G  G PG
Sbjct: 376 EAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG 435

Query: 380 APGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEAL 439
             GP G QG +G  GPKG  G+ G  G  G QGP+G PG  G QGA       G   E  
Sbjct: 436 PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP------GPAGEEG 489

Query: 440 QRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGI 499
           +R       G PG  GP G  G +G  G+ G PG DG  G KG+ G+ G  G+ G KG  
Sbjct: 490 KR----GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 545

Query: 500 GLPGLPGANGMKGEKGDSGMPGPQGP-SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPM 558
           G PG PG  G+ G +G +G PG  GP   +GP G PG  G PGP GP G  G  G  G  
Sbjct: 546 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 605

Query: 559 GPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTS 618
           GP G  G  G+ GEKG  G PG R   GLPGKDGE G  G PGP G  G+ GE+G    S
Sbjct: 606 GPKGANGEPGKAGEKGLPGAPGLR---GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 662

Query: 619 PSQHVP 624
             Q +P
Sbjct: 663 GFQGLP 668



 Score =  396 bits (1018), Expect = e-110
 Identities = 250/604 (41%), Positives = 289/604 (47%), Gaps = 139/604 (23%)

Query: 115  PSECNCPAGPPGKRGK---RGRRGESGPPGQPGPQGP---PGPKGDKGEQGDQG-PRMVF 167
            P     P GP G+ G+    G +GE GP G+PGP GP   PGP G++G++G +G P  V 
Sbjct: 442  PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 501

Query: 168  PKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEP 227
            P    G   A          +G  GQ G  GP G PG RGP G  G  G  G PG PGEP
Sbjct: 502  PIGPPGERGAPGN-------RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554

Query: 228  GKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGI---PGPKG---EP 281
            G PG +GL G  G  G +G +G  G PG +G+ G PG  GA GQ G+   PGPKG   EP
Sbjct: 555  GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 614

Query: 282  GEQGEKG---------------------DAGENGPKGDTGEKGDPGSSA----AGIKGEP 316
            G+ GEKG                       G  GP G+ GE+G PG S      G  G P
Sbjct: 615  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674

Query: 317  GESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPG---------LPGLPGTKGERGEA 367
            GE G+PG +G PG  G PGL G +GE GF G +G PG         LPG PGT G +G +
Sbjct: 675  GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 734

Query: 368  GPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATE 427
            GP G      PGA GP G QG  G RG  G  G +G++GD G +GP G PG+ G +G   
Sbjct: 735  GPAG-----PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG--- 786

Query: 428  IIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDM 487
                               +TGP GPPGP G  G KGE G PG  G  G +G  G +G+ 
Sbjct: 787  -------------------LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827

Query: 488  GDPGMTGEKGGIGLPGLPGANGMKGE---KGDSGMPGPQGPSII---------------- 528
            G PG  G  G  G  G PGA G +GE   KGD+G PGPQGPS                  
Sbjct: 828  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887

Query: 529  ---------------------------GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPH 561
                                       GPPGPPGP G  GP G  G  GP G  G  G  
Sbjct: 888  GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947

Query: 562  GPAGPKGERGE------KGAMGEPGP------RGPYGLPGKDGEPGLDGFPGPRGEKGDL 609
            GPAGP GE+GE       GA G PGP      RG  GLPG+ GE G  G PGP GE G  
Sbjct: 948  GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ 1007

Query: 610  GEKG 613
            G  G
Sbjct: 1008 GAPG 1011



 Score =  395 bits (1016), Expect = e-110
 Identities = 231/520 (44%), Positives = 265/520 (50%), Gaps = 38/520 (7%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPG---------------PKGDKGEQGDQGPRM 165
            P G PG  G  G +G SGP G PG QGPPG               PKGD+G+ G++GP  
Sbjct: 718  PRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG 777

Query: 166  VFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG 225
               K     L+            G++G+ GPPGP G  G RG PG+ G+ GP G  G  G
Sbjct: 778  APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAG 837

Query: 226  EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
             PG  G+ G  G  G  GQKG  GAPG  G +G  G  G  G  G  G  G +G PG  G
Sbjct: 838  PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 897

Query: 286  EKGDAGENGPKGDTGEKGDPG----SSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKG 341
              G AG  GP G  G  G PG    S   G KG  G+SG PG+ GEPGL G  G PG KG
Sbjct: 898  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957

Query: 342  EPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKG 400
            EPG  GP G  G PG  G  G+RG  G PG RGERG PG PGP G+ G+ G  G  G +G
Sbjct: 958  EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRG 1017

Query: 401  DRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTV-----TGPPGPPG 455
              G  G  G  GP G PG++G  GA      +G       R  T  V      GPPG PG
Sbjct: 1018 PPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPG 1077

Query: 456  PQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKG 515
            P G  G +G++G  G  G  G  G  G++G  G  G  G+KG  G PG  G  G +G  G
Sbjct: 1078 PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1137

Query: 516  DSGMPGPQGPS----IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERG 571
              G+PGP GPS      GP GP GP GPPGP+GP G  G  G  GP+GP GP G  GE G
Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETG 1197

Query: 572  EKGAMGEPGPRGPYGLPGKDGEPGLD----GFPGPRGEKG 607
              G  G PGP GP G PG    PG+D       GPR EKG
Sbjct: 1198 PAGPPGNPGPPGPPGPPG----PGIDMSAFAGLGPR-EKG 1232



 Score =  395 bits (1014), Expect = e-110
 Identities = 233/561 (41%), Positives = 274/561 (48%), Gaps = 106/561 (18%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGP---------PGPKGDKGEQGDQGPRMVFPKINHG 173
           GP G  G RG  G+ GP G PGP GP         PG KG+ G  G +GP          
Sbjct: 336 GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP---------- 385

Query: 174 FLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKD------GPRGMPGVPGEP 227
                         +G QG  G PG PG PGP G  G+ G D      G  G PG+ G P
Sbjct: 386 --------------EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431

Query: 228 GKPGEQGLMGP---LGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQ 284
           G PG +G  GP    GP G KG  G PGI G  G++G  G PG  G  G PGP GE G++
Sbjct: 432 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491

Query: 285 GEKGDAGENGPKGDTGEKGDPGS-------SAAGIKGEPGE---------SGRPGQKGEP 328
           G +G+ G  GP G  GE+G PG+         AG KG PGE          G  G  G P
Sbjct: 492 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP 551

Query: 329 GLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQ 387
           G PGLPG  G+ G PG  GPQG+ G  G PG  G  G  GP G RG+ G  G PGPKG  
Sbjct: 552 GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 388 GESGTRGPK---------GSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEA 438
           GE G  G K         G  G  GE G +G  GP GP G++G+QGA     + G     
Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG----- 666

Query: 439 LQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGG 498
                   + GPPGPPG  G  G +G  G  G PG+ G +G +G  G+ G PG  G +G 
Sbjct: 667 --------LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718

Query: 499 IGLPGLPGANGMKGEKGDSGMPGPQGP-------------SIIGPPGPPGPHGPPGPMGP 545
            GLPG PG +G KG  G +G PG QGP              I GP G  G  G  GP G 
Sbjct: 719 RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 778

Query: 546 HGLPGPKGTDGPMGPHGPAGPKGERGE------------KGAMGEPGPRGPYGLPGKDGE 593
            G  G +G  GP+GP GPAG  GE+GE            +GA GE G  GP G  G  G 
Sbjct: 779 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838

Query: 594 PGLDGFPGPRGEKGDLGEKGE 614
           PG DG PG +GE+G+ G+KG+
Sbjct: 839 PGADGQPGAKGEQGEAGQKGD 859



 Score =  394 bits (1011), Expect = e-109
 Identities = 236/544 (43%), Positives = 273/544 (50%), Gaps = 81/544 (14%)

Query: 122  AGPPGKRGKRGRRGESGPPGQPGPQG---PPGPKGDKGEQGDQG-------PRMVFPKIN 171
            AGPPG  G  G RGE G PG  G QG   PPGP G+ G+ GDQG       P +V P+  
Sbjct: 641  AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 700

Query: 172  HGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPG 231
             GF          R   G QG  GP G PG PG  GP G +G  GP G  G PG  G PG
Sbjct: 701  RGFPG-------ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 753

Query: 232  EQGLMGPLGPPGQKGSIG------APGIPGMNGQKGEPGLPGAVGQNGI------PGPKG 279
            E+G  G  GP G +G +G      APG  G  G  G  G PG  G NG       PGP G
Sbjct: 754  ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 813

Query: 280  EPGEQGEKGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPGLPGLPG 338
              G +G  G+ GE GP G  G  G PG+    G KGE GE+G+ G  G PG  G  G PG
Sbjct: 814  SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 873

Query: 339  IKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKG 397
             +G  G  GP+G  G  G PG  G  G AG  G  G  G PG PGP G  G+ G +G +G
Sbjct: 874  PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG 933

Query: 398  SKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQ 457
              G  G  G+ G QGP GPPG+KG+ G                       +G  GPPGPQ
Sbjct: 934  DSGPPGRAGEPGLQGPAGPPGEKGEPGDDG-------------------PSGAEGPPGPQ 974

Query: 458  GLQGPKG---------EQGSPGIPGMDGEQGLKGSKGDMGD---------PGMTGEKGGI 499
            GL G +G         E+G PG+PG  GE G +G+ G  GD         PG+TG  G  
Sbjct: 975  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034

Query: 500  GLPGLPGANGMKGEKGDSGMPGPQGPS-IIGPPGPPGPHGPPGPMGPHGLPGPKG---TD 555
            G  G PGA+G  G  G +G+ G +G +  +G PG PGP G PGP GP G  G +G     
Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1094

Query: 556  GPMGPHGPAG------PKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDL 609
            GPMGP GPAG      P+G RG+KG  GEPG R   GL G  G  GL G PGP G  GD 
Sbjct: 1095 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER---GLKGHRGFTGLQGLPGPPGPSGDQ 1151

Query: 610  GEKG 613
            G  G
Sbjct: 1152 GASG 1155



 Score =  393 bits (1009), Expect = e-109
 Identities = 236/547 (43%), Positives = 274/547 (50%), Gaps = 67/547 (12%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
           P GPPG  GK G  GE+G PG+ G +GPPGP+G +G  G  G   V     +  L   + 
Sbjct: 241 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 300

Query: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240
                 +KG+ G  G  G PGP GPRG PG+ G+ GP G  G  G  G+PG      P G
Sbjct: 301 EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG------PAG 354

Query: 241 PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG 300
           PPG  G  G PG PG  G KGE G  GA G  G  GP+GEPG  G  G AG +G  G  G
Sbjct: 355 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 414

Query: 301 EKGDPGSSAA----GIKGEPGESGRPG------------QKGEPGLPGLPGLPGIKGEPG 344
             G  GS+ A    G  G PG  G PG            Q GEPG+ G  G  G KGEPG
Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474

Query: 345 FIGPQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRG 403
             GPQG PG  G  G +G RGE G  G  G  GE GAPG +G  G+ G  GPKG+ G+RG
Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 534

Query: 404 EKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPK 463
             G +G +G  G PG+ G+ G        G   +A  +       GP G PG  G  GP 
Sbjct: 535 PSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQ----GKVGPSGAPGEDGRPGPP 590

Query: 464 GEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQ 523
           G QG+ G PG+    G  G KG  G+PG  GEKG  G PGL G  G  GE G +G PGP 
Sbjct: 591 GPQGARGQPGV---MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647

Query: 524 GPS----IIGPPGPPGPHGPPGPMGP---------HGLPGPKGTDGPMGPHGPAGPKGER 570
           GP+      G PGP G  G PGP GP          G+PG  G  G +GP G  G  GER
Sbjct: 648 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 707

Query: 571 GEKGAMGEPGPR---------------GPYGLPGKDGEPGLDGFP---------GPRGEK 606
           G  GA G  GPR               GP G PG  G PGL G P         GP+G++
Sbjct: 708 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR 767

Query: 607 GDLGEKG 613
           GD+GEKG
Sbjct: 768 GDVGEKG 774



 Score =  389 bits (1000), Expect = e-108
 Identities = 247/617 (40%), Positives = 295/617 (47%), Gaps = 137/617 (22%)

Query: 121  PAGPPGKRGKRGR---RGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSA 177
            P G PG+RG  G    +G +G PG+PG  G PG +G  G  GD GP              
Sbjct: 526  PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP-------------- 571

Query: 178  DQQLIKRRLIKGDQGQAGPPGP------------PGPPGPRGPPGDTGKDGPRGMPGVPG 225
             Q  +      G+ G+ GPPGP            PGP G  G PG  G+ G  G PG+ G
Sbjct: 572  -QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG 630

Query: 226  EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
             PGK GE G  GP GP G  G  G  G PG +G +G PG PG  G+ G PG +G PGE G
Sbjct: 631  LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAG 690

Query: 286  EKGDAGENGPKGDTGEKGDPGSSAA-------------GIKGEPGESGRPGQKGEPGLPG 332
              G  G  G +G  GE+G PG+                G KG  G +G PG +G PGL G
Sbjct: 691  APGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 750

Query: 333  LP------GLPGIKGEPGFI---GPQGEPGL------------PGLPGTKGERGEAGPPG 371
            +P      G+ G KG+ G +   GP+G PG             PG  G  GE+GE GPPG
Sbjct: 751  MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 810

Query: 372  ----------RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGE---KGDSGAQGPRGPPG 418
                       GERGE G PGP G  G  G  G  G+KG++GE   KGD+GA GP+GP G
Sbjct: 811  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 870

Query: 419  QKGDQGATEIIDYNG-----------NLHEALQRI---TTLTVTGPPGPPGPQGLQGPKG 464
              G QG T +    G               A  R+    +    GPPGPPGP G  GPKG
Sbjct: 871  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 930

Query: 465  EQGSPGIPGMDGEQGLK------GSKGDMGD------------PGMTGEKGGIGLPGLPG 506
             +G  G PG  GE GL+      G KG+ GD             G+ G++G +GLPG  G
Sbjct: 931  ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG 990

Query: 507  ANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHGPPGPMGPHGLPGPKGT---DGPMGPHG 562
              G  G  G SG PG QG P   G  GPPGP GPPG  GP G PG +G+   DGP G  G
Sbjct: 991  ERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDG 1050

Query: 563  PAGPKGERGEKGAMGEPGPRGPYGLPGKDGEP------------------------GLDG 598
             AG KG+RGE GA+G PG  GP G PG  G                          G+ G
Sbjct: 1051 AAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1110

Query: 599  FPGPRGEKGDLGEKGEK 615
              GPRG+KG+ GE GE+
Sbjct: 1111 PQGPRGDKGEAGEPGER 1127



 Score =  388 bits (997), Expect = e-108
 Identities = 235/530 (44%), Positives = 267/530 (50%), Gaps = 72/530 (13%)

Query: 121 PAGPPGKRGKRGRRGE------SGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF 174
           PAG PG +G +G  GE      SGP G  GP GPPG  GD GE G  G            
Sbjct: 214 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK----------- 262

Query: 175 LSADQQLIKRRLIKGDQGQAGPPGPPGPP---GPRGPPGDTGKDGPRGMPGVPGEPGKPG 231
                     R   G QG  G PG PG P   G RG PG  G  G  G PGV GE G PG
Sbjct: 263 -------AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 315

Query: 232 EQGLMGPLGP---PGQKGSIGAPGIPGMNGQKGEP---GLPGAVGQNGIPGPKGEPGEQG 285
           E G  GP+GP   PG++G  G  G  G  G  G+P   G PG VG  G PG  G PG +G
Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 375

Query: 286 EKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGF 345
           E G  G  GP+G  G +G+PG+   G  G  G SG PG  G PG  G  G PGI G PGF
Sbjct: 376 EAGPTGARGPEGAQGPRGEPGT--PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433

Query: 346 IGPQGEPGLPGLPGTKGERGEAGPPG----RGERGEPGAPGPKGKQGESGTRGPKGSKGD 401
            GP+G PG  G  G  G +G+ G PG    +GE+G  G PGP G Q   G  GP G +G 
Sbjct: 434 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ---GAPGPAGEEGK 490

Query: 402 RGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQG 461
           RG +G+ G  GP GPPG++G  G       +G               G PG  GP GL G
Sbjct: 491 RGARGEPGGVGPIGPPGERGAPGNRGFPGQDG----------LAGPKGAPGERGPSGLAG 540

Query: 462 PK---GEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGG---IGLPGLPGANGMKGEKG 515
           PK   G+ G PG PG+ G +GL G  GD G  G  G  G     G PG PG  G +G+ G
Sbjct: 541 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG 600

Query: 516 DSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGA 575
             G PGP+G +  G PG  G  G PG  G  GLPG  G  G  GP GPAGP GERGE+GA
Sbjct: 601 VMGFPGPKGAN--GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658

Query: 576 ---------MGEPGPRGPYGLPGKDGEPGLDGFP---GPRGEKGDLGEKG 613
                     G PGP G  G PG  G PG  G P   GPRGE+G  GE+G
Sbjct: 659 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG 708



 Score =  362 bits (928), Expect = e-100
 Identities = 232/575 (40%), Positives = 263/575 (45%), Gaps = 141/575 (24%)

Query: 147 GPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPR 206
           G PGPKG KGE GD                          IK   G  GPPGP GP G +
Sbjct: 98  GQPGPKGQKGEPGD--------------------------IKDIVGPKGPPGPQGPAGEQ 131

Query: 207 GPPGDTGKDG------PRGMPGVPGEPGKPGE---------------------------- 232
           GP GD G  G      PRG  G PG PG PG                             
Sbjct: 132 GPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKA 191

Query: 233 --------QGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGA---VGQNGIPGPKGEP 281
                   QG MGP+GP G  G  GAPG  G  G  GEPG PG    +G  G PGP G+P
Sbjct: 192 GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 251

Query: 282 GEQGE---KGDAGENGPKGDTGEKGDPG----------------------SSAAGIKGE- 315
           G+ GE    G AGE GP G  G +G PG                      + A G+KGE 
Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311

Query: 316 --PGESGRPGQKGEPGLP---------------GLPGLPGIKGEPGFIGPQGEPGLPGLP 358
             PGE+G PG  G  GLP               G  G PG  G PG +GP G PG PG P
Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 371

Query: 359 GTKGERGEAGPPG-------RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ 411
           G KGE G  G  G       RGE G PG+PGP G  G  GT G  G+KG  G  G +GA 
Sbjct: 372 GAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431

Query: 412 GPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGI 471
           G  GP G  G QGAT  +   G   E         + G  G  GP+G  GP G QG+PG 
Sbjct: 432 GFPGPRGPPGPQGATGPLGPKGQTGEP-------GIAGFKGEQGPKGEPGPAGPQGAPGP 484

Query: 472 PGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGM------KGEKGDSGMPGPQG- 524
            G +G++G +G  G +G  G  GE+G  G  G PG +G+       GE+G SG+ GP+G 
Sbjct: 485 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 544

Query: 525 ---PSIIGPPGPPGPH---GPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGE 578
              P   G PG PG     G PG  GP G  GP G  G  G  GP GP+G RG+ G MG 
Sbjct: 545 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 579 PGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
           PGP+G  G PGK GE GL G PG RG  G  GE G
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 639



 Score =  249 bits (637), Expect = 4e-66
 Identities = 159/390 (40%), Positives = 192/390 (49%), Gaps = 65/390 (16%)

Query: 112  REAPSECNCPAGPPGKR------GKRGRRGESGPP---GQPGPQGPPGPKGDKGEQGDQG 162
            R  P   N   GPPG        G +G RG+SGPP   G+PG QGP GP G+KGE GD G
Sbjct: 904  RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDG 963

Query: 163  PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPP---GDTGKDGPRG 219
            P           L+  + ++     +G++G  G PGP G PG +G P   GD G  GP G
Sbjct: 964  PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023

Query: 220  MPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKG 279
             PG+ G  G+PG +G  G  GPPG+    GA G+ G  G+ G  G PGA G  G PGP G
Sbjct: 1024 PPGLTGPAGEPGREGSPGADGPPGRD---GAAGVKGDRGETGAVGAPGAPGPPGSPGPAG 1080

Query: 280  EPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGI 339
              G+QG++G+AG  GP G +G  G     A GI+G  G  G  G+ GEPG  GL      
Sbjct: 1081 PTGKQGDRGEAGAQGPMGPSGPAG-----ARGIQGPQGPRGDKGEAGEPGERGL------ 1129

Query: 340  KGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSK 399
            KG  GF G QG PG PG  G +G  G AGP   G RG PG  GP GK G +G  GP G  
Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGDQGASGPAGP--SGPRGPPGPVGPSGKDGANGIPGPIGPP 1187

Query: 400  GDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGP--- 456
            G RG  G++G  GP G PG                              GPPGPPGP   
Sbjct: 1188 GPRGRSGETGPAGPPGNPGP----------------------------PGPPGPPGPGID 1219

Query: 457  ----QGLQGPKGEQGSPGIPGMDGEQGLKG 482
                 GL GP+ E+G   +  M  +Q   G
Sbjct: 1220 MSAFAGL-GPR-EKGPDPLQYMRADQAAGG 1247



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 38/97 (39%), Positives = 45/97 (46%), Gaps = 16/97 (16%)

Query: 533 PPGPHGPPGPMGPHGLPGPKGTDGP-------------MGPHGPAGPKGERGEKGAMGEP 579
           P  P G   P+ P  L    G  GP             +GP GP GP+G  GE+G  G+ 
Sbjct: 78  PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137

Query: 580 GPRGPYGLP---GKDGEPGLDGFPGPRGEKGDLGEKG 613
           G +G  G P   G+DGEPG  G PGP G  G  G  G
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPG 174



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 7/66 (10%)

Query: 557 PMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPG--KD-----GEPGLDGFPGPRGEKGDL 609
           P  P G   P        A G+PGP+G  G PG  KD     G PG  G  G +G +GD 
Sbjct: 78  PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137

Query: 610 GEKGEK 615
           G+KGEK
Sbjct: 138 GDKGEK 143


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  408 bits (1048), Expect = e-114
 Identities = 245/546 (44%), Positives = 281/546 (51%), Gaps = 62/546 (11%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF--LSADQQ 180
           G  G  G RGR GE G PG PGP GPPGP G  G  G+   +M       GF   +   Q
Sbjct: 72  GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMA-----GGFDEKAGGAQ 126

Query: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRG---------PPGDTGKDGPRGMPGVPG------ 225
           L   +   G  G  GPPGP G PGP+G          PG +G  GPRG PG PG      
Sbjct: 127 LGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG 186

Query: 226 EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
           E GKPG+ G  GP GP G +G  G PG+PG+ G +G PGL GA G+ G PG KGE G  G
Sbjct: 187 EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 246

Query: 286 EKGDAGENGPKGDTGEKGDPG----SSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKG 341
           E G  G  GP+G  GE+G  G    + A G  G+PG +G PG  G  G PG PG PG KG
Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 306

Query: 342 E---------PGFIGPQGEPGLPGLP------------GTKGERGEAGPPG-RGERGEPG 379
           E          G  GP+GEPG PG P            G  G +G AG PG  G  G PG
Sbjct: 307 EAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG 366

Query: 380 APGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEAL 439
             GP G QG +G  GPKG  G+ G  G  G QGP+G PG  G QGA       G   E  
Sbjct: 367 PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP------GPAGEEG 420

Query: 440 QRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGI 499
           +R       G PG  GP G  G +G  G+ G PG DG  G KG+ G+ G  G+ G KG  
Sbjct: 421 KR----GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476

Query: 500 GLPGLPGANGMKGEKGDSGMPGPQGP-SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPM 558
           G PG PG  G+ G +G +G PG  GP   +GP G PG  G PGP GP G  G  G  G  
Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 536

Query: 559 GPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTS 618
           GP G  G  G+ GEKG  G PG R   GLPGKDGE G  G PGP G  G+ GE+G    S
Sbjct: 537 GPKGANGEPGKAGEKGLPGAPGLR---GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 593

Query: 619 PSQHVP 624
             Q +P
Sbjct: 594 GFQGLP 599



 Score =  396 bits (1018), Expect = e-110
 Identities = 250/604 (41%), Positives = 289/604 (47%), Gaps = 139/604 (23%)

Query: 115 PSECNCPAGPPGKRGK---RGRRGESGPPGQPGPQGP---PGPKGDKGEQGDQG-PRMVF 167
           P     P GP G+ G+    G +GE GP G+PGP GP   PGP G++G++G +G P  V 
Sbjct: 373 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432

Query: 168 PKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEP 227
           P    G   A          +G  GQ G  GP G PG RGP G  G  G  G PG PGEP
Sbjct: 433 PIGPPGERGAPGN-------RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485

Query: 228 GKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGI---PGPKG---EP 281
           G PG +GL G  G  G +G +G  G PG +G+ G PG  GA GQ G+   PGPKG   EP
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 545

Query: 282 GEQGEKG---------------------DAGENGPKGDTGEKGDPGSSA----AGIKGEP 316
           G+ GEKG                       G  GP G+ GE+G PG S      G  G P
Sbjct: 546 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605

Query: 317 GESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPG---------LPGLPGTKGERGEA 367
           GE G+PG +G PG  G PGL G +GE GF G +G PG         LPG PGT G +G +
Sbjct: 606 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 665

Query: 368 GPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATE 427
           GP G      PGA GP G QG  G RG  G  G +G++GD G +GP G PG+ G +G   
Sbjct: 666 GPAG-----PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG--- 717

Query: 428 IIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDM 487
                              +TGP GPPGP G  G KGE G PG  G  G +G  G +G+ 
Sbjct: 718 -------------------LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758

Query: 488 GDPGMTGEKGGIGLPGLPGANGMKGE---KGDSGMPGPQGPSII---------------- 528
           G PG  G  G  G  G PGA G +GE   KGD+G PGPQGPS                  
Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818

Query: 529 ---------------------------GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPH 561
                                      GPPGPPGP G  GP G  G  GP G  G  G  
Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 878

Query: 562 GPAGPKGERGE------KGAMGEPGP------RGPYGLPGKDGEPGLDGFPGPRGEKGDL 609
           GPAGP GE+GE       GA G PGP      RG  GLPG+ GE G  G PGP GE G  
Sbjct: 879 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ 938

Query: 610 GEKG 613
           G  G
Sbjct: 939 GAPG 942



 Score =  395 bits (1016), Expect = e-110
 Identities = 241/570 (42%), Positives = 281/570 (49%), Gaps = 92/570 (16%)

Query: 114 APSECNCPAGPPGKRGKRGRRGESGP---------PGQPGPQGPPGPKGDKGEQGDQGPR 164
           +P E   P GP G RG  G RG +GP          GQPGP GPPGP G  G  G  G  
Sbjct: 244 SPGENGSP-GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 302

Query: 165 MVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKD------GPR 218
               K   G   A       R  +G QG  G PG PG PGP G  G+ G D      G  
Sbjct: 303 GA--KGEAGPTGA-------RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 353

Query: 219 GMPGVPGEPGKPGEQGLMGP---LGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIP 275
           G PG+ G PG PG +G  GP    GP G KG  G PGI G  G++G  G PG  G  G P
Sbjct: 354 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 413

Query: 276 GPKGEPGEQGEKGDAGENGPKGDTGEKGDPGS-------SAAGIKGEPGE---------S 319
           GP GE G++G +G+ G  GP G  GE+G PG+         AG KG PGE          
Sbjct: 414 GPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK 473

Query: 320 GRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEP 378
           G  G  G PG PGLPG  G+ G PG  GPQG+ G  G PG  G  G  GP G RG+ G  
Sbjct: 474 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 533

Query: 379 GAPGPKGKQGESGTRGPK---------GSKGDRGEKGDSGAQGPRGPPGQKGDQGATEII 429
           G PGPKG  GE G  G K         G  G  GE G +G  GP GP G++G+QGA    
Sbjct: 534 GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 593

Query: 430 DYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGD 489
            + G             + GPPGPPG  G  G +G  G  G PG+ G +G +G  G+ G 
Sbjct: 594 GFQG-------------LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640

Query: 490 PGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGP-------------SIIGPPGPPGP 536
           PG  G +G  GLPG PG +G KG  G +G PG QGP              I GP G  G 
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700

Query: 537 HGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGE------------KGAMGEPGPRGP 584
            G  GP G  G  G +G  GP+GP GPAG  GE+GE            +GA GE G  GP
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760

Query: 585 YGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
            G  G  G PG DG PG +GE+G+ G+KG+
Sbjct: 761 PGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790



 Score =  395 bits (1016), Expect = e-110
 Identities = 231/520 (44%), Positives = 265/520 (50%), Gaps = 38/520 (7%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPG---------------PKGDKGEQGDQGPRM 165
            P G PG  G  G +G SGP G PG QGPPG               PKGD+G+ G++GP  
Sbjct: 649  PRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG 708

Query: 166  VFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG 225
               K     L+            G++G+ GPPGP G  G RG PG+ G+ GP G  G  G
Sbjct: 709  APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAG 768

Query: 226  EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
             PG  G+ G  G  G  GQKG  GAPG  G +G  G  G  G  G  G  G +G PG  G
Sbjct: 769  PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 828

Query: 286  EKGDAGENGPKGDTGEKGDPG----SSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKG 341
              G AG  GP G  G  G PG    S   G KG  G+SG PG+ GEPGL G  G PG KG
Sbjct: 829  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888

Query: 342  EPGFIGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKG 400
            EPG  GP G  G PG  G  G+RG  G PG RGERG PG PGP G+ G+ G  G  G +G
Sbjct: 889  EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRG 948

Query: 401  DRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTV-----TGPPGPPG 455
              G  G  G  GP G PG++G  GA      +G       R  T  V      GPPG PG
Sbjct: 949  PPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPG 1008

Query: 456  PQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKG 515
            P G  G +G++G  G  G  G  G  G++G  G  G  G+KG  G PG  G  G +G  G
Sbjct: 1009 PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1068

Query: 516  DSGMPGPQGPS----IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERG 571
              G+PGP GPS      GP GP GP GPPGP+GP G  G  G  GP+GP GP G  GE G
Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETG 1128

Query: 572  EKGAMGEPGPRGPYGLPGKDGEPGLD----GFPGPRGEKG 607
              G  G PGP GP G PG    PG+D       GPR EKG
Sbjct: 1129 PAGPPGNPGPPGPPGPPG----PGIDMSAFAGLGPR-EKG 1163



 Score =  394 bits (1011), Expect = e-109
 Identities = 236/544 (43%), Positives = 273/544 (50%), Gaps = 81/544 (14%)

Query: 122  AGPPGKRGKRGRRGESGPPGQPGPQG---PPGPKGDKGEQGDQG-------PRMVFPKIN 171
            AGPPG  G  G RGE G PG  G QG   PPGP G+ G+ GDQG       P +V P+  
Sbjct: 572  AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 631

Query: 172  HGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPG 231
             GF          R   G QG  GP G PG PG  GP G +G  GP G  G PG  G PG
Sbjct: 632  RGFPG-------ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684

Query: 232  EQGLMGPLGPPGQKGSIG------APGIPGMNGQKGEPGLPGAVGQNGI------PGPKG 279
            E+G  G  GP G +G +G      APG  G  G  G  G PG  G NG       PGP G
Sbjct: 685  ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 744

Query: 280  EPGEQGEKGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPGLPGLPG 338
              G +G  G+ GE GP G  G  G PG+    G KGE GE+G+ G  G PG  G  G PG
Sbjct: 745  SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 804

Query: 339  IKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKG 397
             +G  G  GP+G  G  G PG  G  G AG  G  G  G PG PGP G  G+ G +G +G
Sbjct: 805  PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG 864

Query: 398  SKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQ 457
              G  G  G+ G QGP GPPG+KG+ G                       +G  GPPGPQ
Sbjct: 865  DSGPPGRAGEPGLQGPAGPPGEKGEPGDDG-------------------PSGAEGPPGPQ 905

Query: 458  GLQGPKG---------EQGSPGIPGMDGEQGLKGSKGDMGD---------PGMTGEKGGI 499
            GL G +G         E+G PG+PG  GE G +G+ G  GD         PG+TG  G  
Sbjct: 906  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965

Query: 500  GLPGLPGANGMKGEKGDSGMPGPQGPS-IIGPPGPPGPHGPPGPMGPHGLPGPKG---TD 555
            G  G PGA+G  G  G +G+ G +G +  +G PG PGP G PGP GP G  G +G     
Sbjct: 966  GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1025

Query: 556  GPMGPHGPAG------PKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDL 609
            GPMGP GPAG      P+G RG+KG  GEPG R   GL G  G  GL G PGP G  GD 
Sbjct: 1026 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER---GLKGHRGFTGLQGLPGPPGPSGDQ 1082

Query: 610  GEKG 613
            G  G
Sbjct: 1083 GASG 1086



 Score =  393 bits (1009), Expect = e-109
 Identities = 236/547 (43%), Positives = 274/547 (50%), Gaps = 67/547 (12%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
           P GPPG  GK G  GE+G PG+ G +GPPGP+G +G  G  G   V     +  L   + 
Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 231

Query: 181 LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240
                 +KG+ G  G  G PGP GPRG PG+ G+ GP G  G  G  G+PG      P G
Sbjct: 232 EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG------PAG 285

Query: 241 PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG 300
           PPG  G  G PG PG  G KGE G  GA G  G  GP+GEPG  G  G AG +G  G  G
Sbjct: 286 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 345

Query: 301 EKGDPGSSAA----GIKGEPGESGRPG------------QKGEPGLPGLPGLPGIKGEPG 344
             G  GS+ A    G  G PG  G PG            Q GEPG+ G  G  G KGEPG
Sbjct: 346 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 405

Query: 345 FIGPQGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKGDRG 403
             GPQG PG  G  G +G RGE G  G  G  GE GAPG +G  G+ G  GPKG+ G+RG
Sbjct: 406 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 465

Query: 404 EKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPK 463
             G +G +G  G PG+ G+ G        G   +A  +       GP G PG  G  GP 
Sbjct: 466 PSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQ----GKVGPSGAPGEDGRPGPP 521

Query: 464 GEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQ 523
           G QG+ G PG+    G  G KG  G+PG  GEKG  G PGL G  G  GE G +G PGP 
Sbjct: 522 GPQGARGQPGV---MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578

Query: 524 GPS----IIGPPGPPGPHGPPGPMGP---------HGLPGPKGTDGPMGPHGPAGPKGER 570
           GP+      G PGP G  G PGP GP          G+PG  G  G +GP G  G  GER
Sbjct: 579 GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER 638

Query: 571 GEKGAMGEPGPR---------------GPYGLPGKDGEPGLDGFP---------GPRGEK 606
           G  GA G  GPR               GP G PG  G PGL G P         GP+G++
Sbjct: 639 GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR 698

Query: 607 GDLGEKG 613
           GD+GEKG
Sbjct: 699 GDVGEKG 705



 Score =  389 bits (1000), Expect = e-108
 Identities = 247/617 (40%), Positives = 295/617 (47%), Gaps = 137/617 (22%)

Query: 121  PAGPPGKRGKRGR---RGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSA 177
            P G PG+RG  G    +G +G PG+PG  G PG +G  G  GD GP              
Sbjct: 457  PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP-------------- 502

Query: 178  DQQLIKRRLIKGDQGQAGPPGP------------PGPPGPRGPPGDTGKDGPRGMPGVPG 225
             Q  +      G+ G+ GPPGP            PGP G  G PG  G+ G  G PG+ G
Sbjct: 503  -QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG 561

Query: 226  EPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQG 285
             PGK GE G  GP GP G  G  G  G PG +G +G PG PG  G+ G PG +G PGE G
Sbjct: 562  LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAG 621

Query: 286  EKGDAGENGPKGDTGEKGDPGSSAA-------------GIKGEPGESGRPGQKGEPGLPG 332
              G  G  G +G  GE+G PG+                G KG  G +G PG +G PGL G
Sbjct: 622  APGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 681

Query: 333  LP------GLPGIKGEPGFI---GPQGEPGL------------PGLPGTKGERGEAGPPG 371
            +P      G+ G KG+ G +   GP+G PG             PG  G  GE+GE GPPG
Sbjct: 682  MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741

Query: 372  ----------RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGE---KGDSGAQGPRGPPG 418
                       GERGE G PGP G  G  G  G  G+KG++GE   KGD+GA GP+GP G
Sbjct: 742  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 801

Query: 419  QKGDQGATEIIDYNG-----------NLHEALQRI---TTLTVTGPPGPPGPQGLQGPKG 464
              G QG T +    G               A  R+    +    GPPGPPGP G  GPKG
Sbjct: 802  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 861

Query: 465  EQGSPGIPGMDGEQGLK------GSKGDMGD------------PGMTGEKGGIGLPGLPG 506
             +G  G PG  GE GL+      G KG+ GD             G+ G++G +GLPG  G
Sbjct: 862  ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG 921

Query: 507  ANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHGPPGPMGPHGLPGPKGT---DGPMGPHG 562
              G  G  G SG PG QG P   G  GPPGP GPPG  GP G PG +G+   DGP G  G
Sbjct: 922  ERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDG 981

Query: 563  PAGPKGERGEKGAMGEPGPRGPYGLPGKDGEP------------------------GLDG 598
             AG KG+RGE GA+G PG  GP G PG  G                          G+ G
Sbjct: 982  AAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1041

Query: 599  FPGPRGEKGDLGEKGEK 615
              GPRG+KG+ GE GE+
Sbjct: 1042 PQGPRGDKGEAGEPGER 1058



 Score =  388 bits (997), Expect = e-108
 Identities = 235/530 (44%), Positives = 267/530 (50%), Gaps = 72/530 (13%)

Query: 121 PAGPPGKRGKRGRRGE------SGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF 174
           PAG PG +G +G  GE      SGP G  GP GPPG  GD GE G  G            
Sbjct: 145 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK----------- 193

Query: 175 LSADQQLIKRRLIKGDQGQAGPPGPPGPP---GPRGPPGDTGKDGPRGMPGVPGEPGKPG 231
                     R   G QG  G PG PG P   G RG PG  G  G  G PGV GE G PG
Sbjct: 194 -------AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 246

Query: 232 EQGLMGPLGP---PGQKGSIGAPGIPGMNGQKGEP---GLPGAVGQNGIPGPKGEPGEQG 285
           E G  GP+GP   PG++G  G  G  G  G  G+P   G PG VG  G PG  G PG +G
Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 306

Query: 286 EKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGF 345
           E G  G  GP+G  G +G+PG+   G  G  G SG PG  G PG  G  G PGI G PGF
Sbjct: 307 EAGPTGARGPEGAQGPRGEPGT--PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364

Query: 346 IGPQGEPGLPGLPGTKGERGEAGPPG----RGERGEPGAPGPKGKQGESGTRGPKGSKGD 401
            GP+G PG  G  G  G +G+ G PG    +GE+G  G PGP G Q   G  GP G +G 
Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ---GAPGPAGEEGK 421

Query: 402 RGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQG 461
           RG +G+ G  GP GPPG++G  G       +G               G PG  GP GL G
Sbjct: 422 RGARGEPGGVGPIGPPGERGAPGNRGFPGQDG----------LAGPKGAPGERGPSGLAG 471

Query: 462 PK---GEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGG---IGLPGLPGANGMKGEKG 515
           PK   G+ G PG PG+ G +GL G  GD G  G  G  G     G PG PG  G +G+ G
Sbjct: 472 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG 531

Query: 516 DSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGA 575
             G PGP+G +  G PG  G  G PG  G  GLPG  G  G  GP GPAGP GERGE+GA
Sbjct: 532 VMGFPGPKGAN--GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589

Query: 576 ---------MGEPGPRGPYGLPGKDGEPGLDGFP---GPRGEKGDLGEKG 613
                     G PGP G  G PG  G PG  G P   GPRGE+G  GE+G
Sbjct: 590 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG 639



 Score =  360 bits (923), Expect = 3e-99
 Identities = 231/573 (40%), Positives = 262/573 (45%), Gaps = 141/573 (24%)

Query: 149 PGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGP 208
           PGPKG KGE GD                          IK   G  GPPGP GP G +GP
Sbjct: 31  PGPKGQKGEPGD--------------------------IKDIVGPKGPPGPQGPAGEQGP 64

Query: 209 PGDTGKDG------PRGMPGVPGEPGKPGE------------------------------ 232
            GD G  G      PRG  G PG PG PG                               
Sbjct: 65  RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG 124

Query: 233 ------QGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGA---VGQNGIPGPKGEPGE 283
                 QG MGP+GP G  G  GAPG  G  G  GEPG PG    +G  G PGP G+PG+
Sbjct: 125 AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184

Query: 284 QGE---KGDAGENGPKGDTGEKGDPG----------------------SSAAGIKGE--- 315
            GE    G AGE GP G  G +G PG                      + A G+KGE   
Sbjct: 185 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244

Query: 316 PGESGRPGQKGEPGLP---------------GLPGLPGIKGEPGFIGPQGEPGLPGLPGT 360
           PGE+G PG  G  GLP               G  G PG  G PG +GP G PG PG PG 
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304

Query: 361 KGERGEAGPPG-------RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGP 413
           KGE G  G  G       RGE G PG+PGP G  G  GT G  G+KG  G  G +GA G 
Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364

Query: 414 RGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPG 473
            GP G  G QGAT  +   G   E         + G  G  GP+G  GP G QG+PG  G
Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEP-------GIAGFKGEQGPKGEPGPAGPQGAPGPAG 417

Query: 474 MDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGM------KGEKGDSGMPGPQG--- 524
            +G++G +G  G +G  G  GE+G  G  G PG +G+       GE+G SG+ GP+G   
Sbjct: 418 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 477

Query: 525 -PSIIGPPGPPGPH---GPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPG 580
            P   G PG PG     G PG  GP G  GP G  G  G  GP GP+G RG+ G MG PG
Sbjct: 478 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 537

Query: 581 PRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
           P+G  G PGK GE GL G PG RG  G  GE G
Sbjct: 538 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 570



 Score =  251 bits (642), Expect = 1e-66
 Identities = 165/451 (36%), Positives = 186/451 (41%), Gaps = 137/451 (30%)

Query: 289 DAGENGPKGDTGEKGD----------PGSSA-------------AGIKGEPGESGRPGQK 325
           D  + GPKG  GE GD          PG                 G KG PG  GR G+ 
Sbjct: 27  DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86

Query: 326 GEPGLPGLPGLPGIKGEP------------------------------------------ 343
           G PG PG PG PG  G P                                          
Sbjct: 87  GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146

Query: 344 ------GFIGPQGEPGLPGLPGTKGERGEAGPPGR-------------GERGEPGA---- 380
                 GF G  GEPG PG+ G  G RG  GPPG+             GERG PG     
Sbjct: 147 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 206

Query: 381 -----------------PGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQ 423
                            PG  G +GE+G  G KG  G  GE G  G  GPRG PG++G  
Sbjct: 207 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 266

Query: 424 GATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGE------ 477
           G        GN              G PGP GP G  GP G  G PG PG  GE      
Sbjct: 267 GPAGAAGARGN-------------DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 313

Query: 478 QGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGP 536
           +G +G++G  G+PG  G  G  G  G PG +G+ G KG +G PG  G P   GP GPPGP
Sbjct: 314 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 373

Query: 537 HGPPGPMGPHGL------------PGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGP 584
            G  GP+GP G              GPKG  GP GP G  GP GE G++GA GEPG  GP
Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 433

Query: 585 YGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK 615
            G PG+ G PG  GFPG  G  G  G  GE+
Sbjct: 434 IGPPGERGAPGNRGFPGQDGLAGPKGAPGER 464



 Score =  249 bits (637), Expect = 4e-66
 Identities = 159/390 (40%), Positives = 192/390 (49%), Gaps = 65/390 (16%)

Query: 112  REAPSECNCPAGPPGKR------GKRGRRGESGPP---GQPGPQGPPGPKGDKGEQGDQG 162
            R  P   N   GPPG        G +G RG+SGPP   G+PG QGP GP G+KGE GD G
Sbjct: 835  RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDG 894

Query: 163  PRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPP---GDTGKDGPRG 219
            P           L+  + ++     +G++G  G PGP G PG +G P   GD G  GP G
Sbjct: 895  PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954

Query: 220  MPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKG 279
             PG+ G  G+PG +G  G  GPPG+    GA G+ G  G+ G  G PGA G  G PGP G
Sbjct: 955  PPGLTGPAGEPGREGSPGADGPPGRD---GAAGVKGDRGETGAVGAPGAPGPPGSPGPAG 1011

Query: 280  EPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGI 339
              G+QG++G+AG  GP G +G  G     A GI+G  G  G  G+ GEPG  GL      
Sbjct: 1012 PTGKQGDRGEAGAQGPMGPSGPAG-----ARGIQGPQGPRGDKGEAGEPGERGL------ 1060

Query: 340  KGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSK 399
            KG  GF G QG PG PG  G +G  G AGP   G RG PG  GP GK G +G  GP G  
Sbjct: 1061 KGHRGFTGLQGLPGPPGPSGDQGASGPAGP--SGPRGPPGPVGPSGKDGANGIPGPIGPP 1118

Query: 400  GDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGP--- 456
            G RG  G++G  GP G PG                              GPPGPPGP   
Sbjct: 1119 GPRGRSGETGPAGPPGNPGP----------------------------PGPPGPPGPGID 1150

Query: 457  ----QGLQGPKGEQGSPGIPGMDGEQGLKG 482
                 GL GP+ E+G   +  M  +Q   G
Sbjct: 1151 MSAFAGL-GPR-EKGPDPLQYMRADQAAGG 1178



 Score =  228 bits (580), Expect = 2e-59
 Identities = 139/325 (42%), Positives = 162/325 (49%), Gaps = 37/325 (11%)

Query: 309 AAGIKGEPGESGRPGQKGEPGLPG-LPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEA 367
           AA ++ +  +  +PG KG+ G PG +  + G KG PG  GP GE G  G  G KGE+G  
Sbjct: 18  AAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP 77

Query: 368 GPPGR-GERGEPGAPGPKGKQGESGTRGPKGS-----KGDRGEK----------GDSGAQ 411
           GP GR GE G PG PGP G  G  G  G  G+      G   EK          G  G  
Sbjct: 78  GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 137

Query: 412 GPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGI 471
           GPRGPPG  G  G      + GN              G PG PG  G  GP+G  G PG 
Sbjct: 138 GPRGPPGPAGAPGPQ---GFQGN-------------PGEPGEPGVSGPMGPRGPPGPPGK 181

Query: 472 PGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGP 530
           PG DGE G  G  G+ G PG  G +G  G PGLPG  G +G  G  G  G  G P + G 
Sbjct: 182 PGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE 241

Query: 531 PGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGK 590
            G PG +G PGPMGP GLPG +G  GP    G AG +G  G+ G  G PGP GP G PG 
Sbjct: 242 SGSPGENGSPGPMGPRGLPGERGRTGPA---GAAGARGNDGQPGPAGPPGPVGPAGGPGF 298

Query: 591 DGEPGLDGFPGPRGEKGDLGEKGEK 615
            G PG  G  GP G +G  G +G +
Sbjct: 299 PGAPGAKGEAGPTGARGPEGAQGPR 323


>gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens]
          Length = 703

 Score =  406 bits (1044), Expect = e-113
 Identities = 273/710 (38%), Positives = 333/710 (46%), Gaps = 170/710 (23%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++ P+                   G  GQ G  G PG PGP G
Sbjct: 138 AIGMPGRVGSPGDAGLSIIGPR-------------------GPPGQPGTRGFPGFPGPIG 178

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQ----------------------- 244
             G  G  GP+G  G+ G PG+PG QG  G  G  G+                       
Sbjct: 179 LDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALK 238

Query: 245 ------------------------------KGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
                                         +G  G PG PG +G  G PGLPG +G  G+
Sbjct: 239 LLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGL 298

Query: 275 ---PGPKGEPGEQ---GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
              PGPKG+PG Q   G KG+ G  G  G  G KG PG + AG+KGEPG  G  G+KG  
Sbjct: 299 PGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAE 358

Query: 329 GLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGP 383
           G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+ G PG PG 
Sbjct: 359 GSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQVGPPGQPGD 416

Query: 384 KGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT 443
           KG++G +G +GP G KG +GE G             KG     E++DYNGN++EALQ I 
Sbjct: 417 KGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGNINEALQEIR 458

Query: 444 TLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE-- 495
           TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G   
Sbjct: 459 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPG 518

Query: 496 -------KGGIGLPGLPGANGMKGEKGDSGMPGPQGPS----------IIGPPGPP---- 534
                  KG  G PG PG  G KGE G +G PG +G +          + G PGP     
Sbjct: 519 KDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQGVPGPKGEAG 578

Query: 535 -----------------GPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMG 577
                            GP G PG  G  G PGP GT GP+G  GPAGPKGERG KG  G
Sbjct: 579 LDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPG 638

Query: 578 EPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
             GP G  GLPG  G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 639 MTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 688



 Score =  154 bits (390), Expect = 2e-37
 Identities = 109/283 (38%), Positives = 125/283 (44%), Gaps = 41/283 (14%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ G
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPG 166

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
            +G                        GP G  G  G  GPKG+ G  G PG  G QG K
Sbjct: 167 TRGFPGF-------------------PGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQK 207

Query: 482 GSKGDMGD----------PGMTGEKGGIGLPGLPGANGMKGE-----KGDSGMPGPQGPS 526
           G KG  G+          P        I L  LP  N ++       K  +        S
Sbjct: 208 GEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQAS 267

Query: 527 IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYG 586
           I GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G
Sbjct: 268 IQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPG 324

Query: 587 LPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           +PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 325 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 367



 Score =  154 bits (390), Expect = 2e-37
 Identities = 92/211 (43%), Positives = 110/211 (52%), Gaps = 23/211 (10%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPG---PKGDKGEQGDQG-PRMVFPKINHGFLSAD 178
           GPPG  G++G RG+ G  G PGPQGPPG   P G KGE G  G P     K   G   + 
Sbjct: 491 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSP 550

Query: 179 QQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGK------PGE 232
            +       KG+ G+ G PG  G  G  GP G+ G DG +G  G  GE G       PG 
Sbjct: 551 GE-------KGEAGEKGNPGAEGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGA 603

Query: 233 QGLMGPLGPPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP---GPKGEPGEQGE 286
            GL G  GPPG  G IG PG  G  G+   KG+PG+ G  G  G+P   GP G+ G +GE
Sbjct: 604 SGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGE 663

Query: 287 KGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
           +G  G  GPKGD G++G PG  A    GE G
Sbjct: 664 RGKKGSRGPKGDKGDQGAPGLDAPCPLGEDG 694


>gi|22027595 alpha 1 type XIII collagen isoform 12 [Homo sapiens]
          Length = 691

 Score =  405 bits (1042), Expect = e-113
 Identities = 272/698 (38%), Positives = 331/698 (47%), Gaps = 158/698 (22%)

Query: 28  ARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKT 87
           AR   P +     L++ ++   L    +T +LQAR+  LE+ +G             ++T
Sbjct: 37  ARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGE----------QQMET 86

Query: 88  MVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQG 147
            +  +V +LL +K   H  + R A +    CNCP   P  +G  GR      PG PG +G
Sbjct: 87  AILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCP---PAFQGPTGR------PGLPGDKG 137

Query: 148 PPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG 207
             G  G  G  GD G  ++ P+                   G  GQ G  G PG PGP G
Sbjct: 138 AIGMPGRVGSPGDAGLSIIGPR-------------------GPPGQPGTRGFPGFPGPIG 178

Query: 208 PPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQ----------------------- 244
             G  G  GP+G  G+ G PG+PG QG  G  G  G+                       
Sbjct: 179 LDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALK 238

Query: 245 ------------------------------KGSIGAPGIPGMNGQKGEPGLPGAVGQNGI 274
                                         +G  G PG PG +G  G PGLPG +G  G+
Sbjct: 239 LLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGL 298

Query: 275 ---PGPKGEPGEQ---GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEP 328
              PGPKG+PG Q   G KG+ G  G  G  G KG PG + AG+KGEPG  G  G+KG  
Sbjct: 299 PGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAE 358

Query: 329 GLPGLPGLPGIKGEPG-----FIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGP 383
           G PGLPGL G KGE G       G +GEPG PGLPG  G +GEAG    G+ G PG PG 
Sbjct: 359 GSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVD--GQVGPPGQPGD 416

Query: 384 KGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT 443
           KG++G +G +GP G KG +GE G             KG     E++DYNGN++EALQ I 
Sbjct: 417 KGERGAAGEQGPDGPKGSKGEPG-------------KG-----EMVDYNGNINEALQEIR 458

Query: 444 TLTVTGPP------GPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGE-- 495
           TL + GPP      GPPG  G+ G KGE G PG PG DGE+G +G  GDMG PG  G   
Sbjct: 459 TLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPG 518

Query: 496 -------KGGIGLPGLPGANGMKGEKGDSGMPGPQGPS-IIGPPGPPGPHGPPGPMGPHG 547
                  KG  G PG PG  G KGE G +G PG +G +   G PG  G  G PGP G  G
Sbjct: 519 KDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQGVPGPKGEAG 578

Query: 548 LPGPK------------------GTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPG 589
           L G K                  GT GP+G  GPAGPKGERG KG  G  GP G  GLPG
Sbjct: 579 LDGAKGEKGFQGEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPG 638

Query: 590 KDGEPGLDGFPGPRGEKGDLGEKGEK--VTSPSQHVPC 625
             G PG  G  G RG+KG  G KG+K    +P    PC
Sbjct: 639 LHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 676



 Score =  154 bits (390), Expect = 2e-37
 Identities = 109/283 (38%), Positives = 125/283 (44%), Gaps = 41/283 (14%)

Query: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ--GPRGPPGQKG 421
           R EA     G    P   GP G+ G  G +G  G  G  G  GD+G    GPRGPPGQ G
Sbjct: 107 RREAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPG 166

Query: 422 DQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLK 481
            +G                        GP G  G  G  GPKG+ G  G PG  G QG K
Sbjct: 167 TRGFPGF-------------------PGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQK 207

Query: 482 GSKGDMGD----------PGMTGEKGGIGLPGLPGANGMKGE-----KGDSGMPGPQGPS 526
           G KG  G+          P        I L  LP  N ++       K  +        S
Sbjct: 208 GEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQAS 267

Query: 527 IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYG 586
           I GPPGPPGP GP GP+G  GLPGP G   P G  GP GPKG+ G +G  G  G RG  G
Sbjct: 268 IQGPPGPPGPPGPSGPLGHPGLPGPMG---PPGLPGPPGPKGDPGIQGYHGRKGERGMPG 324

Query: 587 LPGKDGEPGLDGFP--GPRGEKGDLGEKGEKVTSPSQHVPCLI 627
           +PGK G  G  G    G +GE G  G KGEK    S  +P L+
Sbjct: 325 MPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLL 367



 Score =  153 bits (386), Expect = 5e-37
 Identities = 88/207 (42%), Positives = 108/207 (52%), Gaps = 27/207 (13%)

Query: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182
           GPPG  G++G RG+ G  G PGPQGPPG  G  G +G+ G         H     ++   
Sbjct: 491 GPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENG---------HPGSPGEKGE- 540

Query: 183 KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDG------PRGMPGVPGEPGKPGEQGLM 236
                KG+ GQAG PG  G  G +G PG  G  G        G+ G  GE G  GE+G  
Sbjct: 541 -----KGETGQAGSPGEKGEAGEKGNPGAEGLQGVPGPKGEAGLDGAKGEKGFQGEKGDR 595

Query: 237 GPLGPPGQKGSIGAPGIPGMNGQ---KGEPGLPGAVGQNGIP---GPKGEPGEQGEKGDA 290
           GPLG PG  G IG PG  G  G+   KG+PG+ G  G  G+P   GP G+ G +GE+G  
Sbjct: 596 GPLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKK 655

Query: 291 GENGPKGDTGEKGDPGSSAAGIKGEPG 317
           G  GPKGD G++G PG  A    GE G
Sbjct: 656 GSRGPKGDKGDQGAPGLDAPCPLGEDG 682


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  405 bits (1041), Expect = e-113
 Identities = 236/510 (46%), Positives = 268/510 (52%), Gaps = 32/510 (6%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPR--MVFPKINHGFLSADQQ 180
            GP G +G+ G  G+ GPPG  G +G  G  G  G  G QGP+  + FP    GF  A  +
Sbjct: 683  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP----GFPGASGE 738

Query: 181  LIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLG 240
               R L  G  G  G  GP GP G RGP G TGK G +G  G  G  G PGE+GL GP G
Sbjct: 739  KGARGL-SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG 797

Query: 241  PPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTG 300
            P G  G  G PG PG +G  G PG  G VG  G  GP G PG  G +G AGE GP G+ G
Sbjct: 798  PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG 857

Query: 301  EKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGT 360
              G PG    G +G PG +G+ G KG+PG PG PG  G  G  GF G +G PG  G PG 
Sbjct: 858  HPGPPG--PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915

Query: 361  KGERGEAGPPG----RGER---------GEPGAPGPKGKQGESGTRGPKGSKGDRGEKGD 407
            KG  G +GPPG     GER         G PG PGP+G  G +G +G  G KG  G  G 
Sbjct: 916  KGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGR 975

Query: 408  SGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRIT--TLTVTGPPGPPGPQGLQGPKGE 465
             G QGP G PG  G  G        G + +  Q+ T       GPPGPPGP G  G  G 
Sbjct: 976  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1035

Query: 466  QGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGP 525
             G+ G PG  G QG  G+KGD G  G  G  G IGL GLPG +G KGE GD G       
Sbjct: 1036 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGP------ 1089

Query: 526  SIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585
              +GPPGPPGP GP GP G  G  GP G  G +GP G  G  GE G  G  GEPG +GP 
Sbjct: 1090 --MGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1147

Query: 586  GLPGKDGEPGLDGFPGPRGEKGDLGEKGEK 615
            G  G+ GE G  G PGP G KG  G+ G K
Sbjct: 1148 GERGEKGESGQPGEPGPPGPKGPTGDDGPK 1177



 Score =  402 bits (1034), Expect = e-112
 Identities = 250/574 (43%), Positives = 282/574 (49%), Gaps = 104/574 (18%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGP------QGPPGPKGDKGEQGDQGPRMVFPKINHGF 174
            P G PG+ G RG  G  GPPG PGP       GP GPKG  G QG+ GP           
Sbjct: 513  PRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP----------- 561

Query: 175  LSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQG 234
                Q     + + G QG  GP G  GP G  G PG  G DGP G PG  G PG  G QG
Sbjct: 562  -PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 620

Query: 235  LMGPLGP---PGQKGSIGAPGIPGMNG---QKGEPGLPGAVGQNGIPGPKGEPGEQGEKG 288
              GP GP   PG +G  G  GI G+ G   +KGE G PG  G  G+ G +GE G  G +G
Sbjct: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680

Query: 289  DAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGE---PGF 345
            + G  GPKG TG  GDPG         PG  G  G+ G PGLPG PG  G KG    PGF
Sbjct: 681  EDGPEGPKGRTGPTGDPGP--------PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 732

Query: 346  IGPQGEPGLPGLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKGDRG- 403
             G  GE G  GL G  G RGE GP G RG+RG  GA G  G +G SG  GP G  G+RG 
Sbjct: 733  PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL 792

Query: 404  --EKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPG---PQG 458
               +G +G  GP+GPPG  G  G        G        +     TGPPGPPG   PQG
Sbjct: 793  PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE-------VGFQGKTGPPGPPGVVGPQG 845

Query: 459  LQG---PKGEQGSPGIPGMDGEQGL------KGSKGDMGDPGMTGEKGGIGLPGLPGANG 509
              G   P GE+G PG PG  GEQGL      +G+KGD G PG  G+ G  GL G PG  G
Sbjct: 846  AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERG 905

Query: 510  M---------KGEKGDSGMPGPQGP----------SIIGPPGPPGPHGPPGPMGPHGLPG 550
            +         KG +G SG PGP G             IGPPG PGP GPPG  G  G+PG
Sbjct: 906  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 965

Query: 551  PKG---------TDGPMGPHGPAGP------------------KGERGEKGAMGEPGPRG 583
             KG           GP+G  GPAGP                  KG +G KG  G PGP G
Sbjct: 966  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025

Query: 584  PYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVT 617
            P G  G+ G  G DG PG RG +G  G KG++ T
Sbjct: 1026 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1059



 Score =  401 bits (1030), Expect = e-111
 Identities = 253/586 (43%), Positives = 293/586 (50%), Gaps = 104/586 (17%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGP---------PGPKGDKGEQGDQGPR-MVFPKINH 172
            GPPGK G+RGR G  G  G PG  G          PG  G+KG +GD G + +  P    
Sbjct: 443  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 502

Query: 173  GFLSADQQLIKRRLI--KGDQGQAGPPGPPGPPGP------RGPPGDTGKDGPRGMPGVP 224
            G    D ++  R L    G +G  GP GPPG PGP       GP G  G  GP+G PG P
Sbjct: 503  GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562

Query: 225  GEPGKPGEQGLMGP---LGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQN--------- 272
            G+ G PG QGL GP   +GP G+KG  G PG+PGM G  G PG PG  G           
Sbjct: 563  GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 622

Query: 273  ------GIPGP---------------KGEPGEQGEKGDAGENGPKGDTGEKGDPGS---- 307
                  G PGP               KGE GE G  G  G+ G KGD GE G PGS    
Sbjct: 623  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 682

Query: 308  ------SAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGE------PGFIGPQGEPGLP 355
                     G  G+PG  G  G+KG+ G+PGLPG PG +G       PGF G  GE G  
Sbjct: 683  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742

Query: 356  GLPGTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKGDR---GEKGDSGAQ 411
            GL G  G RGE GP G RG+RG  GA G  G +G SG  GP G  G+R   G +G +G  
Sbjct: 743  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802

Query: 412  GPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPP---GPQGL---QGPKGE 465
            GP+GPPG  G  G        G        +     TGPPGPP   GPQG     GP GE
Sbjct: 803  GPKGPPGPPGKDGLPGHPGQRG-------EVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855

Query: 466  QGSPGIPGMDGEQGL------KGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGM 519
            +G PG PG  GEQGL      +G+KGD G PG  G+ G  GL G PG  G+ G  G  G+
Sbjct: 856  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGL 915

Query: 520  PGPQGPSIIGPPGPP------------GPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPK 567
             G +GPS  GPPGP             GP GPPG  GP G PG  G  G  G  GP GP 
Sbjct: 916  KGNEGPS--GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973

Query: 568  GERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
            G  G +G +G PGP GP G+ G+DG+ G  G PG +G KG+ GE G
Sbjct: 974  GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHG 1019



 Score =  399 bits (1025), Expect = e-111
 Identities = 234/514 (45%), Positives = 266/514 (51%), Gaps = 35/514 (6%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPR-MVFPKINHGFLSADQ 179
            P GP G+RG RG  G+SG  G  G  GP GP G++G  G QGP     PK   G    D 
Sbjct: 756  PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 815

Query: 180  QLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPL 239
             L      +G+ G  G  GPPGPPG  GP G  G+ GP G  G PG PG PGEQGL G  
Sbjct: 816  -LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 874

Query: 240  GPPGQKGSIGAPGIPGMNGQKG---------------EPGLPGAVGQNGIPGPKGEPGEQ 284
            G  G KG  G PG PG +G  G                PGL G  G +G PGP G PGE+
Sbjct: 875  GKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER 934

Query: 285  GEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPG 344
            G  G  G  GP G  G +G PG  AAG KG PGE G  G  G  G+ G  GLPG  G PG
Sbjct: 935  GAAGSGGPIGPPGRPGPQGPPG--AAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG 992

Query: 345  FIGP---QGEPGLPGLPGTKGERGEAGPPGR-GERGEPGAPGPKGKQGESGTRGPKGSKG 400
              G    +GE G PG  GTKG +GE GPPG  G  G  G PG  G  GE G RGP+G  G
Sbjct: 993  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1052

Query: 401  DRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQ 460
             +G++G  G  GP GP G +G  G +      G++             GPPGPPGP+G  
Sbjct: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM----------GPPGPPGPRGPA 1102

Query: 461  GPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMP 520
            GP G  G  G PG  G  G  G KG+ G+ G  G +G  G+ G  G  G KGE G  G P
Sbjct: 1103 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEP 1162

Query: 521  GPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPG 580
            GP GP   GP G  GP G PGP+G  G PGP G  GP G  G  G +GE GE G  G PG
Sbjct: 1163 GPPGPK--GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1220

Query: 581  PRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
            P G  G PG  G+ G  G PG  G +G  G KG+
Sbjct: 1221 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1254



 Score =  396 bits (1018), Expect = e-110
 Identities = 243/589 (41%), Positives = 289/589 (49%), Gaps = 117/589 (19%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFP-------------- 168
            GP GK G  G  G  GPPG PG +GPPG KG++G  G QGP + +P              
Sbjct: 587  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGP-LGYPGPRGVKGVDGIRGL 645

Query: 169  ------KINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPG 222
                  K   GF      +     +KGD+G+ G PG  G  GP GP G TG  G  G PG
Sbjct: 646  KGHKGEKGEDGFPGFKGDIG----VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 701

Query: 223  VPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPG 282
            + GE GK G  GL G  G  G KGS+G PG PG +G+KG  GL G  G  G  GP G  G
Sbjct: 702  LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRG 761

Query: 283  EQGEKGDAGENGPKGDTGEKGDPGSSAA-GIKGEPGESGRPGQKGEPGLPG---LPGLPG 338
            ++G +G  G++G KG +G  G  G     G+ G  G +G PG KG PG PG   LPG PG
Sbjct: 762  QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 821

Query: 339  IKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGS 398
             +GE GF G  G PG PG+ G +G  GE GP   GERG PG PGP G+QG  GT G +G+
Sbjct: 822  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--MGERGHPGPPGPPGEQGLPGTAGKEGT 879

Query: 399  KGDRGEKGDSGAQGP---RGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPG 455
            KGD G  G  G  GP   RG PG++G  G        GN              GP GPPG
Sbjct: 880  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN-------------EGPSGPPG 926

Query: 456  PQGLQG------------PKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPG 503
            P G  G            P G  G  G PG  GE+G+ G KG +G  G  G +G +GLPG
Sbjct: 927  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 986

Query: 504  L---PGANGMKGEKGDSGMPGPQGPS----IIGPPGPPGP-------------------- 536
                PG  G  G+KG+ G PG +G        GPPGPPGP                    
Sbjct: 987  PAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1046

Query: 537  ----------------HGPPGPMGPHGLPGPKGTD------GPMGPHGPAGPKGERGEKG 574
                            +GPPGP+G  GLPGP G        GPMGP GP GP+G  G  G
Sbjct: 1047 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1106

Query: 575  A---------MGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
            A         +G  GP G  G PG+ G PG+ G PG +G +G+ GEKGE
Sbjct: 1107 ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155



 Score =  388 bits (996), Expect = e-107
 Identities = 229/545 (42%), Positives = 265/545 (48%), Gaps = 102/545 (18%)

Query: 113  EAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINH 172
            E PS    PAG PG+RG  G  G  GPPG+PGPQGPPG  G+KG  G++GP         
Sbjct: 919  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-------- 970

Query: 173  GFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGE 232
                            G  G+ G  GP G PGP GPPG  G+DG +G  G PG+ G  G 
Sbjct: 971  ----------------GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN 1014

Query: 233  QGLMGPLGPPGQKGSIGAPGIPGMNGQ------------------KGEPGLPGAVGQNGI 274
            +G  GP GPPG  G +G PG  G +G+                  +G  G PG +G  G+
Sbjct: 1015 KGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1074

Query: 275  PGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSA-------AGIKGEPGESGRPGQKGE 327
            PGP GE GE G+ G  G  GP G  G  G  G+          G  G PGE G PG+ G 
Sbjct: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1134

Query: 328  PGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQ 387
            PG+ G PG+ G +GE G  G  G+PG PG PG KG  G+ GP  +G  G  G PG  G  
Sbjct: 1135 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGP--KGNPGPVGFPGDPGPP 1192

Query: 388  GESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTV 447
            GE G RG  G+KGDRGE G+ G  G  GP G+ G  G                    L  
Sbjct: 1193 GEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP-------------------LGK 1233

Query: 448  TGPPGPPGPQGLQGPKGEQGSPGI------------------PGMDGEQGLKGSKGDMGD 489
             GP G PG +G QG KG +G PG                   PG DG +GL GS G  G 
Sbjct: 1234 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1293

Query: 490  PGMTGEKGG---IGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPH 546
            PG TG+ G    +G PGLPG  G  G KG+ G PG  G  +IGPPG  G  G  G  GP 
Sbjct: 1294 PGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG--LIGPPGEQGEKGDRGLPGPQ 1351

Query: 547  GLPGPK------GTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFP 600
            G PG K      G  GP+GP GP G  G  G KGA G  GP GP G  G  G P   G P
Sbjct: 1352 GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP---GHP 1408

Query: 601  GPRGE 605
            GP GE
Sbjct: 1409 GPPGE 1413



 Score =  383 bits (983), Expect = e-106
 Identities = 234/539 (43%), Positives = 267/539 (49%), Gaps = 66/539 (12%)

Query: 121  PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQ 180
            P G  G+ G  G RG  GPPG PG QG PG  G +G +GD GP     K     L     
Sbjct: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902

Query: 181  LIKRRL--------IKGDQGQAGPPGPPGPPGPRG------PPGDTGKDGPRGMPGVPGE 226
              +R L        +KG++G +GPPGP G PG RG      P G  G+ GP+G PG  GE
Sbjct: 903  --ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 960

Query: 227  PGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGE 286
             G PGE+G +GP G  G +G +G PG  G  G  GE G  G VG  G  G KG  GE G 
Sbjct: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP 1020

Query: 287  KGDAGENGPKGDTGEKGDPGSSAA-------GIKGEPGESGRPGQKGEPGLPGLPGLPGI 339
             G  G  GP G  G  G  G   A       G KG+ G  G  G  G  GL GLPG  G 
Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080

Query: 340  KGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR----------GERGEPGAPGPKGKQGE 389
            KGE G +GP G PG PG  G  G  G  GP G           GE+GEPG  G  G QGE
Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140

Query: 390  SGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTG 449
             G +GP+G +G++GE G  G  GP GP G  GD G        GN              G
Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGP------KGNPGPV----------G 1184

Query: 450  PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGD---PGMTGEKGGIGLPGLPG 506
             PG PGP G  GP+G+ G+ G  G DGE G  GS G  G+   PG  G++G  G PG  G
Sbjct: 1185 FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEG 1244

Query: 507  ANGMKGEKGDSGM---PGPQGPSIIGPPGPPGPHGP------PGPMGPHGLPGPKGTDGP 557
              G KG KGD G    PG  GP  +GP GP G  GP      PG +G  G PG  G  GP
Sbjct: 1245 RQGGKGAKGDPGAIGAPGKTGP--VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP 1302

Query: 558  MGPHGPAGPKGERGEKGAMGEPGPRGPYGL---PGKDGEPGLDGFPGPRGEKGDLGEKG 613
             GP GP G  G RG+ GA GE G  G  GL   PG+ GE G  G PGP+G  G  GE G
Sbjct: 1303 PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMG 1361



 Score =  378 bits (970), Expect = e-104
 Identities = 237/584 (40%), Positives = 282/584 (48%), Gaps = 107/584 (18%)

Query: 121 PAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGP---------RMVFPKIN 171
           P GP G  G  G +G  GP G PG +GPPG  G  G  G  GP         R      +
Sbjct: 317 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD 376

Query: 172 HGFLSADQQLIKRRLIK-------------GDQGQAGPPGPPGPPGPRGPPGDTGKDGPR 218
            G + A Q+   + +++             G  G+ GP G PG PG +G  GD G  GPR
Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR 436

Query: 219 GMPGVPGEPGKPGEQGLMGP------LGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQN 272
           G  G+ G PGK G +G  G        G PG KG  G  G+PG+ G+KG  G  GA    
Sbjct: 437 GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA---Q 493

Query: 273 GIPGPKGEPGEQGEKGDAG------ENGPKGDTGEKGDPG-------------SSAAGIK 313
           G+PGP GE GE+G+ G+ G      E+GP+G  G KG PG                 G  
Sbjct: 494 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 553

Query: 314 GEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKG---ERGEAGPP 370
           G  GE G PGQ+G PG  GLPG  G  G  G  GPQG+PGLPG+PG+ G     G+ GPP
Sbjct: 554 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 613

Query: 371 GR-------GERGEPGAPGPKGKQGESGTRGPKGSKGDRGE------KGDSGAQGPRGPP 417
           G        G +G  G PGP+G +G  G RG KG KG++GE      KGD G +G RG  
Sbjct: 614 GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 673

Query: 418 GQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGE 477
           G  G +G        G              TGP G PGP GL G KG+ G PG+PG  G 
Sbjct: 674 GVPGSRGEDGPEGPKGR-------------TGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720

Query: 478 QGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPS----IIGPPGP 533
           QG KGS G  G PG +GEKG  GL G  G  G +G  G  G  GP+G +      G  G 
Sbjct: 721 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 780

Query: 534 PGPHGP------PGPMGPHGLPGPKGTDGP------------------MGPHGPAGPKGE 569
            GPHGP      PGP GP+G PGPKG  GP                   G  GP GP G 
Sbjct: 781 DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840

Query: 570 RGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
            G +GA GE GP G  G PG  G PG  G PG  G++G  G+ G
Sbjct: 841 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 884



 Score =  335 bits (859), Expect = 8e-92
 Identities = 218/587 (37%), Positives = 263/587 (44%), Gaps = 148/587 (25%)

Query: 139 PPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPG 198
           PP +    GP G KG+KGE     P M+                            GPPG
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVE--------------------------GPPG 316

Query: 199 PPGP------------PGPRGPPGDTGKDGPRGMPGVPGEPGKPGE-------------- 232
           P GP            PGP G PG+ G  G  G+PG  G PG PG               
Sbjct: 317 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD 376

Query: 233 -----------------------QGLMGPLGPPGQKGSIGAPGIPGMNGQKGE------- 262
                                  +G  GP+G  G+ G +G PG PG+ G+ G+       
Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR 436

Query: 263 --------------------------PGLPGAVGQNGIPGPKGEPGEQGEKGDAGEN--- 293
                                     PG PG  G  G  G  G PGE+G +GD G     
Sbjct: 437 GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 496

Query: 294 GPKGDTGEKGDPGS-SAAGIKGEPGESGRPGQKGEPGLPGLPGLPGI---KGEPGFIGPQ 349
           GP G+ GE+GD G     G+ GE G  G  G KG PG+PG PG+ G+   +G  G +GPQ
Sbjct: 497 GPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQ 556

Query: 350 GEPGLPGLPGTKGERGEAGPPG-------RGERGEPGAPGPKGKQGESGTRGPKGSKGDR 402
           GEPG PG  GT G +G  GP G       +G +G+PG PG  G  G  G  G +G  G +
Sbjct: 557 GEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 616

Query: 403 GEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGP 462
           G +G SG QGP G PG +G +G   I    G+  E  +        G PG  G  G++G 
Sbjct: 617 GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE-------DGFPGFKGDIGVKGD 669

Query: 463 KGEQGSPGIPGMDGEQGLKGSKGDMGD---PGMTGEKGGIGLPGLPGANGMKGEKGDSGM 519
           +GE G PG  G DG +G KG  G  GD   PG+ GEKG +G+PGLPG  G +G KG  G 
Sbjct: 670 RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 729

Query: 520 PGPQGPS-------------IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGP 566
           PG  G S               G  GP GP G  GP G  G  G KGT G  GPHGP G 
Sbjct: 730 PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 789

Query: 567 KGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
           +G  G +G  G PGP+GP G PGKDG P   G PG RGE G  G+ G
Sbjct: 790 RGLPGPQGPNGFPGPKGPPGPPGKDGLP---GHPGQRGEVGFQGKTG 833



 Score =  333 bits (855), Expect = 2e-91
 Identities = 214/485 (44%), Positives = 243/485 (50%), Gaps = 63/485 (12%)

Query: 123  GPPGKRGKRGRRGESGPPGQPGPQGP---PGPKGDKGEQGDQGPRMVF----PKINHGFL 175
            G PG++G +G +GE GPPG PGP GP   PG  G  GE G +GP+  F     +   GF 
Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063

Query: 176  SADQQLIKRRLI-----KGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMP------GVP 224
                 +  + L      KG+ G  GP GPPGPPGPRGP G  G DGP+G P      G P
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123

Query: 225  GEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQ 284
            GE G+PGE G  G  G PG KG  G  G  G +GQ GEPG PG  G  G  GPKG PG  
Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1183

Query: 285  GEKGD---AGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKG 341
            G  GD    GE GP+G  G KGD G       GEPG+ G PG  GE G PG  G  G  G
Sbjct: 1184 GFPGDPGPPGEGGPRGQDGAKGDRGED-----GEPGQPGSPGPTGENGPPGPLGKRGPAG 1238

Query: 342  EPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGD 401
             PG  G QG  G  G PG  G  G+ GP   G  G  G PGP G +G  G+ G +G  G 
Sbjct: 1239 SPGSEGRQGGKGAKGDPGAIGAPGKTGPV--GPAGPAGKPGPDGLRGLPGSVGQQGRPGA 1296

Query: 402  RGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQG 461
             G+ G  G  GP G PG +GD GA                       G  G PG  GL G
Sbjct: 1297 TGQAGPPGPVGPPGLPGLRGDAGA----------------------KGEKGHPGLIGLIG 1334

Query: 462  PKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPG 521
            P GEQG  G  G+ G QG  G KG+MG PG +G  G  G PGLPG  G KG KG +G  G
Sbjct: 1335 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGG 1394

Query: 522  PQGPSIIGPPGPPGPHGPPGP-MGPHGLPGPKGT----DGP-MGPHGPAGPKGERGEKGA 575
            P+G    G  GPPG  GPPG  + P  +  PK T    DG  +     A P G     GA
Sbjct: 1395 PKGEK--GVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG-----GA 1447

Query: 576  MGEPG 580
             G PG
Sbjct: 1448 PGSPG 1452



 Score =  233 bits (593), Expect = 5e-61
 Identities = 142/364 (39%), Positives = 176/364 (48%), Gaps = 63/364 (17%)

Query: 293 NGPKGDTGEKGDPGSSAAG--IKGEPGESGRPGQKGEPGLPGLPGL---PGIKGEPGFIG 347
           +GP+G  GEKG+P     G  ++G PG  G  G  G PG+ G PG    PG +G PG  G
Sbjct: 290 HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 349

Query: 348 PQGEPGLPGLPGTK--------GERGEAGPPGRGERGEP------------GAPGPKGKQ 387
             G  G PG PGT            G+ GP    +  +             G PGP G  
Sbjct: 350 LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 409

Query: 388 GESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTV 447
           G  G  G  GS G +GE GD G QGPRGP G                            +
Sbjct: 410 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQG----------------------------L 441

Query: 448 TGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGA 507
           TGPPG  G +G  G  G +G PG PG+ G++G  G  G  G+ G  G+ G  GLPG PG 
Sbjct: 442 TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 501

Query: 508 NGMKGEKGD---SGMPGPQGP-SIIGPPGPPGPHGPP------GPMGPHGLPGPKGTDGP 557
           +G +G+ G+    G+PG  GP  ++GP GPPG  GPP      GP GP G  GP+G  GP
Sbjct: 502 DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 561

Query: 558 MGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVT 617
            G  G  G +G  G +GA+G  G +GP G PG  G PG DG PG  G++G  G KG +  
Sbjct: 562 PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGP 621

Query: 618 SPSQ 621
           S  Q
Sbjct: 622 SGPQ 625



 Score =  188 bits (478), Expect = 1e-47
 Identities = 124/310 (40%), Positives = 150/310 (48%), Gaps = 34/310 (10%)

Query: 317 GESGRPGQKGEPGL--PGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGE 374
           G  G  G+KGEP +  PG+     ++G PG   P+G  GL G PG +G  G  G P    
Sbjct: 291 GPRGLKGEKGEPAVLEPGML----VEGPPG---PEGPAGLIGPPGIQGNPGPVGDP---- 339

Query: 375 RGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGN 434
            GE G PG  G  G  G  GP G+      +  SG        G KG   A +       
Sbjct: 340 -GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG-------GDKGPVVAAQEAQAQAI 391

Query: 435 LHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTG 494
           L +A      L + GPPGP G  G  GP G+   PG PG+ GE G  G +G  G  G+TG
Sbjct: 392 LQQA-----RLALRGPPGPMGYTGRPGPLGQ---PGSPGLKGESGDLGPQGPRGPQGLTG 443

Query: 495 EKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGT 554
             G  G  G  GA+G +G  GD G+ G +G    G PG PG  G  G  G  GLPGP G 
Sbjct: 444 PPGKAGRRGRAGADGARGMPGDPGVKGDRG--FDGLPGLPGEKGHRGDTGAQGLPGPPGE 501

Query: 555 DGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGE 614
           DG  G  G  GP+G  GE G  G  GP+GP G+PG    PG+ G  GP+G KG LG +GE
Sbjct: 502 DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP---PGVRGMDGPQGPKGSLGPQGE 558

Query: 615 KVTSPSQHVP 624
                 Q  P
Sbjct: 559 PGPPGQQGTP 568



 Score =  152 bits (383), Expect = 1e-36
 Identities = 98/249 (39%), Positives = 114/249 (45%), Gaps = 45/249 (18%)

Query: 121  PAGPPGKRGKRGRRGESGPPG------QPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF 174
            PAG PG  G++G +G  G PG      + GP GP GP G  G  G +G            
Sbjct: 1236 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG------------ 1283

Query: 175  LSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQG 234
                        + G  GQ G PG  G  GP GP G  G  G RG  G  GE G PG  G
Sbjct: 1284 ------------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1331

Query: 235  LMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENG 294
            L+GP G  G+KG  G PG  G  GQKGE G+PGA G  G  GP G PG  G KG  G  G
Sbjct: 1332 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG 1391

Query: 295  PKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLP-----GLPG--IKGEPGFIG 347
            P G  GEK        G++G PG  G PG+  +P    +P      + G  +  E   I 
Sbjct: 1392 PGGPKGEK--------GVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP 1443

Query: 348  PQGEPGLPG 356
              G PG PG
Sbjct: 1444 TGGAPGSPG 1452



 Score =  143 bits (361), Expect = 4e-34
 Identities = 102/288 (35%), Positives = 128/288 (44%), Gaps = 59/288 (20%)

Query: 359 GTKGERGEAGPPGRGERGEPGAPG----PKGKQGESGTRGPKGSKGDRGEKG-----DSG 409
           G + ER +   P R +R     P     P+ ++ +S    P G + +  E       +  
Sbjct: 230 GGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTP-GEEEEILESSLLPPLEEA 288

Query: 410 AQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSP 469
           A GPRG  G+KG+    E                 + V GPPGP GP GL GP G QG+P
Sbjct: 289 AHGPRGLKGEKGEPAVLE---------------PGMLVEGPPGPEGPAGLIGPPGIQGNP 333

Query: 470 GIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSII- 528
           G  G  GE+G          PG  G  G  G PG PG + M   +  SG  G +GP +  
Sbjct: 334 GPVGDPGERG---------PPGRAGLPGSDGAPGPPGTSLMLPFRFGSG-GGDKGPVVAA 383

Query: 529 -----------------GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPK---- 567
                            GPPGP G  G PGP+G  G PG KG  G +GP GP GP+    
Sbjct: 384 QEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTG 443

Query: 568 --GERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKG 613
             G+ G +G  G  G RG  G PG  G+ G DG PG  GEKG  G+ G
Sbjct: 444 PPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 491



 Score =  111 bits (278), Expect = 2e-24
 Identities = 81/239 (33%), Positives = 96/239 (40%), Gaps = 43/239 (17%)

Query: 115  PSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGF 174
            P+  N P GP GKRG  G  G  G  G  G +G PG  G  G+ G  GP     K     
Sbjct: 1221 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1280

Query: 175  LSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRG---------------------PPGDTG 213
            L      + ++   G  GQAGPPGP GPPG  G                     PPG+ G
Sbjct: 1281 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG 1340

Query: 214  KDGPRGMPGVPGEPGKPGEQG---------------LMGPLGPPGQKGSIGAPGIPGMNG 258
            + G RG+PG  G PG+ GE G               L GP GP G KG+ G  G  G  G
Sbjct: 1341 EKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG 1400

Query: 259  QKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPG 317
             +G PG PG  G+   P P   P +     D       G    + D      G  G PG
Sbjct: 1401 VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD-------GSRLMQEDEAIPTGGAPGSPG 1452


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.142    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,811,994
Number of Sequences: 37866
Number of extensions: 3984841
Number of successful extensions: 196314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 539
Number of HSP's successfully gapped in prelim test: 1346
Number of HSP's that attempted gapping in prelim test: 14495
Number of HSP's gapped (non-prelim): 19323
length of query: 642
length of database: 18,247,518
effective HSP length: 109
effective length of query: 533
effective length of database: 14,120,124
effective search space: 7526026092
effective search space used: 7526026092
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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