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Search of human proteins with 125625322
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|125625322 RALBP1 associated Eps domain containing 2 isoform
2 [Homo sapiens]
(659 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 1320 0.0
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 1315 0.0
gi|190886437 RALBP1 associated Eps domain containing 1 isoform b... 380 e-105
gi|190886435 RALBP1 associated Eps domain containing 1 isoform a... 363 e-100
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 91 3e-18
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 91 3e-18
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 91 3e-18
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 81 3e-15
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 81 3e-15
gi|21264315 EH-domain containing 4 [Homo sapiens] 67 4e-11
gi|4503593 epidermal growth factor receptor pathway substrate 15... 67 7e-11
gi|10864047 epidermal growth factor receptor pathway substrate 1... 64 3e-10
gi|21361462 EH-domain containing 2 [Homo sapiens] 61 4e-09
gi|30240932 EH-domain containing 1 [Homo sapiens] 57 4e-08
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 57 5e-08
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 55 3e-07
gi|7657056 EH-domain containing 3 [Homo sapiens] 54 6e-07
gi|24497554 homeobox A13 [Homo sapiens] 51 3e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 50 7e-06
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 50 7e-06
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 50 7e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 50 9e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 50 9e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 50 9e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 50 9e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 49 1e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 49 2e-05
gi|163659920 pannexin 2 isoform 1 [Homo sapiens] 48 3e-05
gi|40353727 synaptopodin isoform A [Homo sapiens] 48 3e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 48 3e-05
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 1320 bits (3416), Expect = 0.0
Identities = 659/659 (100%), Positives = 659/659 (100%)
Query: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60
MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA
Sbjct: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60
Query: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120
ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ
Sbjct: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120
Query: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180
SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED
Sbjct: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180
Query: 181 KQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSS 240
KQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSS
Sbjct: 181 KQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSS 240
Query: 241 GGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFI 300
GGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFI
Sbjct: 241 GGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFI 300
Query: 301 SGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLP 360
SGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLP
Sbjct: 301 SGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLP 360
Query: 361 PTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVT 420
PTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVT
Sbjct: 361 PTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVT 420
Query: 421 SDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPP 480
SDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPP
Sbjct: 421 SDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPP 480
Query: 481 PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSR 540
PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSR
Sbjct: 481 PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSR 540
Query: 541 APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTV 600
APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTV
Sbjct: 541 APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTV 600
Query: 601 QKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659
QKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL
Sbjct: 601 QKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 1315 bits (3404), Expect = 0.0
Identities = 659/660 (99%), Positives = 659/660 (99%), Gaps = 1/660 (0%)
Query: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60
MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA
Sbjct: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60
Query: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120
ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ
Sbjct: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120
Query: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180
SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED
Sbjct: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180
Query: 181 KQ-ETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS 239
KQ ETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS
Sbjct: 181 KQQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS 240
Query: 240 SGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSF 299
SGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSF
Sbjct: 241 SGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSF 300
Query: 300 ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGL 359
ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGL
Sbjct: 301 ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGL 360
Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDV 419
PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDV
Sbjct: 361 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDV 420
Query: 420 TSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTP 479
TSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTP
Sbjct: 421 TSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTP 480
Query: 480 PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLS 539
PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLS
Sbjct: 481 PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLS 540
Query: 540 RAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPT 599
RAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPT
Sbjct: 541 RAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPT 600
Query: 600 VQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659
VQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL
Sbjct: 601 VQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 660
>gi|190886437 RALBP1 associated Eps domain containing 1 isoform b
[Homo sapiens]
Length = 769
Score = 380 bits (976), Expect = e-105
Identities = 274/792 (34%), Positives = 379/792 (47%), Gaps = 186/792 (23%)
Query: 28 LLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVADLFRASQLPAE 87
L LS+ EQ+ YS+LF+ C + G V +LFRA+QLP +
Sbjct: 4 LTLSDAEQKYYSDLFSYCD----------------IESTKKVVVNGRVLELFRAAQLPND 47
Query: 88 TLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKC--ELPLPRFMMSKND 145
+ QI ELCGA R+GYFG +QFYIALKL+A AQSG P+R+ESI +LPLPRF+ SKN+
Sbjct: 48 VVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNE 107
Query: 146 GEIR----FGNPAELHGT----------KVQIPYLTTEKNSFKRMDDEDKQETQSPTMSP 191
E R + + +E G+ + Q+ + ++ + D QE SP +SP
Sbjct: 108 QESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSP 167
Query: 192 LASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGG--------- 242
SPP+SP +++ H ++E+ P P + + SS G
Sbjct: 168 QQSPPTSPHTWRK----HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSP 223
Query: 243 -------------PGTKPL--RHQASL--------IRSFSVERELQDNSSYPDEPWRITE 279
P T L H AS+ + S + E++ SS D+PW+IT+
Sbjct: 224 PPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITD 283
Query: 280 EQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEF 339
EQR+YYVNQF+++QPD + FI GS AK FFTKSKL I ELS+IWELSD D DGALTL EF
Sbjct: 284 EQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEF 343
Query: 340 CAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWD-----------CQLFDSYSES 388
CAAFHL+VARKNGY LPE LP +L P+ + D + S S S
Sbjct: 344 CAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPS 403
Query: 389 LPA------------------------------NQQPRDLNRMEKTSVKDMADLPVPNQD 418
+P+ + Q +L R + L V D
Sbjct: 404 MPSLNQTWPELNQSSEDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSD 463
Query: 419 VTSDDK--QALKSTINEALPKDVSEDPATPKDSNSLKAR-PRSRSYSSTSIEEAMKRGED 475
+ ++K ++K + S + D + + R RS+S TS +
Sbjct: 464 LLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTA----- 518
Query: 476 PPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQS--------- 526
PP PPPRPQ +HSR+SSLD+N+ F + ++G++ PPA+PPRP PSQ+
Sbjct: 519 PPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPV 578
Query: 527 --------------------------------------EQVSEAELLPQL---------- 538
EQ EAE P++
Sbjct: 579 DADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPA 638
Query: 539 ---------SRAPSQAAESSPA--KKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASG 587
S+ + A S+PA K PP KP+RR+ + E++ + T +G
Sbjct: 639 SSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTG 698
Query: 588 PASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALE 647
AA + P++ + K KKAIQ +IR+NKE N VLARLNSELQQQLK+V +ERI+LE
Sbjct: 699 -VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLE 757
Query: 648 NQLEQLRPVTVL 659
QLEQLRP + L
Sbjct: 758 VQLEQLRPFSHL 769
>gi|190886435 RALBP1 associated Eps domain containing 1 isoform a
[Homo sapiens]
Length = 795
Score = 363 bits (931), Expect = e-100
Identities = 275/813 (33%), Positives = 385/813 (47%), Gaps = 202/813 (24%)
Query: 28 LLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVADLFRASQLPAE 87
L LS+ EQ+ YS+LF+ C + G V +LFRA+QLP +
Sbjct: 4 LTLSDAEQKYYSDLFSYCD----------------IESTKKVVVNGRVLELFRAAQLPND 47
Query: 88 TLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKC--ELPLPRFMMSKND 145
+ QI ELCGA R+GYFG +QFYIALKL+A AQSG P+R+ESI +LPLPRF+ SKN+
Sbjct: 48 VVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNE 107
Query: 146 GEIR----FGNPAELHGT----------KVQIPYLTTEKNSFKRMDDEDKQETQSPTMSP 191
E R + + +E G+ + Q+ + ++ + D QE SP +SP
Sbjct: 108 QESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSP 167
Query: 192 LASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGG--------- 242
SPP+SP +++ H ++E+ P P + + SS G
Sbjct: 168 QQSPPTSPHTWRK----HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSP 223
Query: 243 -------------PGTKPL--RHQASL--------IRSFSVERELQDNSSYPDEPWRITE 279
P T L H AS+ + S + E++ SS D+PW+IT+
Sbjct: 224 PPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITD 283
Query: 280 EQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEF 339
EQR+YYVNQF+++QPD + FI GS AK FFTKSKL I ELS+IWELSD D DGALTL EF
Sbjct: 284 EQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEF 343
Query: 340 CAAFHLIVARKNGYPLPEGLPPTLQPEY-------------------------------- 367
CAAFHL+VARKNGY LPE LP +L P+
Sbjct: 344 CAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPS 403
Query: 368 ---LQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL-PVPNQDVTSD- 422
L +P+ + ++++SE ++Q + + D A + PVP + S
Sbjct: 404 MPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKI 463
Query: 423 --DKQALKSTINE---------ALPKDVSEDPATPK-----DSNSLKARPRSRSYS---- 462
+ LK T ++ P D+ E+ N++ S S++
Sbjct: 464 HMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPE 523
Query: 463 ---STSIEEAMKRGEDP----PTP-PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPP 514
S + G P P P PPRPQ +HSR+SSLD+N+ F + ++G++ P
Sbjct: 524 QIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHP 583
Query: 515 PALPPRPCPSQS-----------------------------------------------E 527
PA+PPRP PSQ+ E
Sbjct: 584 PAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDE 643
Query: 528 QVSEAELLPQL-------------------SRAPSQAAESSPA--KKDVLYSQPPSKPIR 566
Q EAE P++ S+ + A S+PA K PP KP+R
Sbjct: 644 QDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVR 703
Query: 567 RKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626
R+ + E++ + T +G AA + P++ + K KKAIQ +IR+NKE N VLA
Sbjct: 704 RRLKSEDELRPEVDEHTQKTG-VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLA 762
Query: 627 RLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659
RLNSELQQQLK+V +ERI+LE QLEQLRP + L
Sbjct: 763 RLNSELQQQLKDVLEERISLEVQLEQLRPFSHL 795
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 90.9 bits (224), Expect = 3e-18
Identities = 97/342 (28%), Positives = 135/342 (39%), Gaps = 39/342 (11%)
Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSG--LPVRIESIKCEL 134
+ F S LPA L +I L + G +F IA+KLI G LPV + I +
Sbjct: 47 NFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
Query: 135 PLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLAS 194
P+ ++S G N + IP + T + PL
Sbjct: 107 PMFSPLISARFGMGSMPN--------LSIPQPLPPAAPITSLSSA----TSGTNLPPLMM 154
Query: 195 PPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS----SGGPGTKPLRH 250
P P L +G + L Q P PY + P GSS GG G ++
Sbjct: 155 PTPLVPSVSTSSLPNGTASLI----QPLPIPYSSS---TLPHGSSYSLMMGGFGGASIQK 207
Query: 251 QASLI-----RSFSVERELQDNSSYPD-EPWRITEEQREYYVNQFRSLQPDPSSFISGSV 304
SLI S S L NS W + + R Y +F +L S ++SG
Sbjct: 208 AQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQ 267
Query: 305 AKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364
A+N +S LS +L+ IW L+D D DG L EF A HL K G PLP LPP L
Sbjct: 268 ARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELV 327
Query: 365 PEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSV 406
P + + DS + +LP+ Q+ ++ +K V
Sbjct: 328 PPSFRGG--------KQIDSINGTLPSYQKMQEEEPQKKLPV 361
Score = 68.6 bits (166), Expect = 2e-11
Identities = 37/90 (41%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334
W IT E+R + QF +L+P +I+G A+NFF +S L P L+ IW LSD + DG +
Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74
Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364
EF A LI + G LP LPP ++
Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLPPIMK 104
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 90.9 bits (224), Expect = 3e-18
Identities = 97/342 (28%), Positives = 135/342 (39%), Gaps = 39/342 (11%)
Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSG--LPVRIESIKCEL 134
+ F S LPA L +I L + G +F IA+KLI G LPV + I +
Sbjct: 47 NFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
Query: 135 PLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLAS 194
P+ ++S G N + IP + T + PL
Sbjct: 107 PMFSPLISARFGMGSMPN--------LSIPQPLPPAAPITSLSSA----TSGTNLPPLMM 154
Query: 195 PPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS----SGGPGTKPLRH 250
P P L +G + L Q P PY + P GSS GG G ++
Sbjct: 155 PTPLVPSVSTSSLPNGTASLI----QPLPIPYSSS---TLPHGSSYSLMMGGFGGASIQK 207
Query: 251 QASLI-----RSFSVERELQDNSSYPD-EPWRITEEQREYYVNQFRSLQPDPSSFISGSV 304
SLI S S L NS W + + R Y +F +L S ++SG
Sbjct: 208 AQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQ 267
Query: 305 AKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364
A+N +S LS +L+ IW L+D D DG L EF A HL K G PLP LPP L
Sbjct: 268 ARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELV 327
Query: 365 PEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSV 406
P + + DS + +LP+ Q+ ++ +K V
Sbjct: 328 PPSFRGG--------KQIDSINGTLPSYQKMQEEEPQKKLPV 361
Score = 68.6 bits (166), Expect = 2e-11
Identities = 37/90 (41%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334
W IT E+R + QF +L+P +I+G A+NFF +S L P L+ IW LSD + DG +
Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74
Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364
EF A LI + G LP LPP ++
Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLPPIMK 104
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 90.9 bits (224), Expect = 3e-18
Identities = 97/342 (28%), Positives = 135/342 (39%), Gaps = 39/342 (11%)
Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSG--LPVRIESIKCEL 134
+ F S LPA L +I L + G +F IA+KLI G LPV + I +
Sbjct: 47 NFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
Query: 135 PLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLAS 194
P+ ++S G N + IP + T + PL
Sbjct: 107 PMFSPLISARFGMGSMPN--------LSIPQPLPPAAPITSLSSA----TSGTNLPPLMM 154
Query: 195 PPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS----SGGPGTKPLRH 250
P P L +G + L Q P PY + P GSS GG G ++
Sbjct: 155 PTPLVPSVSTSSLPNGTASLI----QPLPIPYSSS---TLPHGSSYSLMMGGFGGASIQK 207
Query: 251 QASLI-----RSFSVERELQDNSSYPD-EPWRITEEQREYYVNQFRSLQPDPSSFISGSV 304
SLI S S L NS W + + R Y +F +L S ++SG
Sbjct: 208 AQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQ 267
Query: 305 AKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364
A+N +S LS +L+ IW L+D D DG L EF A HL K G PLP LPP L
Sbjct: 268 ARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELV 327
Query: 365 PEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSV 406
P + + DS + +LP+ Q+ ++ +K V
Sbjct: 328 PPSFRGG--------KQIDSINGTLPSYQKMQEEEPQKKLPV 361
Score = 68.6 bits (166), Expect = 2e-11
Identities = 37/90 (41%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334
W IT E+R + QF +L+P +I+G A+NFF +S L P L+ IW LSD + DG +
Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74
Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364
EF A LI + G LP LPP ++
Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLPPIMK 104
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 80.9 bits (198), Expect = 3e-15
Identities = 100/394 (25%), Positives = 157/394 (39%), Gaps = 29/394 (7%)
Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334
W IT E+R + QF SL+P S FI+G A+NFF +S L P L+ IW L+D + DG +
Sbjct: 15 WAITVEERAKHDQQFHSLKPI-SGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTL--QPEYLQAAFPKPKWDCQLFDSYSESLPAN 392
EF A LI + GY LP LPP + QP + +A + P
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVP 133
Query: 393 QQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSL 452
+ M T V + VP + + + LP PK S+
Sbjct: 134 MGSIPVVGMSPTLVSSVPTAAVPPLANGA-------PPVIQPLPAFAHPAATLPKSSSFS 186
Query: 453 KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP 512
++ P S+ +T +++A + D + PP + ++S L ++F S T SG L
Sbjct: 187 RSGPGSQ--LNTKLQKA--QSFDVASVPPVAEWAVPQSSRLKYRQLFN-SHDKTMSGHLT 241
Query: 513 PPPA---LPPRPCP-SQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPI--R 566
P A L P +Q + + Q + ++ + DV S P P+
Sbjct: 242 GPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPP 301
Query: 567 RKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626
P + + + S + + P ++ + + +K + K N
Sbjct: 302 EYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERG 361
Query: 627 RLNSE------LQQQLKEVHQERIALENQLEQLR 654
L E L+QQ KE QER+A + EQ R
Sbjct: 362 NLELEKRRQALLEQQRKE--QERLAQLERAEQER 393
Score = 77.8 bits (190), Expect = 3e-14
Identities = 85/301 (28%), Positives = 115/301 (38%), Gaps = 43/301 (14%)
Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKCELPL 136
+ F S LP L QI L G +F IA+KLI ++++ + L
Sbjct: 46 NFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIK-------LKLQGYQLPSAL 98
Query: 137 PRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLASPP 196
P M K PA G +P LT +P P+ S P
Sbjct: 99 PPVM--KQQPVAISSAPAFGMGGIASMPPLTAV----------------APV--PMGSIP 138
Query: 197 ---SSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS--SGGPGTKPLRHQ 251
SP VP + + + P P A P+ SS GPG++ L +
Sbjct: 139 VVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQ-LNTK 197
Query: 252 ASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTK 311
+SF V S P W + + R Y F S S ++G A+ +
Sbjct: 198 LQKAQSFDVA------SVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQ 251
Query: 312 SKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAA 371
S L +L+ IW LSD D DG LT EF A HLI +G P LPP L PEY+ +
Sbjct: 252 SSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQP----LPPVLPPEYIPPS 307
Query: 372 F 372
F
Sbjct: 308 F 308
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 80.9 bits (198), Expect = 3e-15
Identities = 100/394 (25%), Positives = 157/394 (39%), Gaps = 29/394 (7%)
Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334
W IT E+R + QF SL+P S FI+G A+NFF +S L P L+ IW L+D + DG +
Sbjct: 15 WAITVEERAKHDQQFHSLKPI-SGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTL--QPEYLQAAFPKPKWDCQLFDSYSESLPAN 392
EF A LI + GY LP LPP + QP + +A + P
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVP 133
Query: 393 QQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSL 452
+ M T V + VP + + + LP PK S+
Sbjct: 134 MGSIPVVGMSPTLVSSVPTAAVPPLANGA-------PPVIQPLPAFAHPAATLPKSSSFS 186
Query: 453 KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP 512
++ P S+ +T +++A + D + PP + ++S L ++F S T SG L
Sbjct: 187 RSGPGSQ--LNTKLQKA--QSFDVASVPPVAEWAVPQSSRLKYRQLFN-SHDKTMSGHLT 241
Query: 513 PPPA---LPPRPCP-SQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPI--R 566
P A L P +Q + + Q + ++ + DV S P P+
Sbjct: 242 GPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPP 301
Query: 567 RKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626
P + + + S + + P ++ + + +K + K N
Sbjct: 302 EYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERG 361
Query: 627 RLNSE------LQQQLKEVHQERIALENQLEQLR 654
L E L+QQ KE QER+A + EQ R
Sbjct: 362 NLELEKRRQALLEQQRKE--QERLAQLERAEQER 393
Score = 77.8 bits (190), Expect = 3e-14
Identities = 85/301 (28%), Positives = 115/301 (38%), Gaps = 43/301 (14%)
Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKCELPL 136
+ F S LP L QI L G +F IA+KLI ++++ + L
Sbjct: 46 NFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIK-------LKLQGYQLPSAL 98
Query: 137 PRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLASPP 196
P M K PA G +P LT +P P+ S P
Sbjct: 99 PPVM--KQQPVAISSAPAFGMGGIASMPPLTAV----------------APV--PMGSIP 138
Query: 197 ---SSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS--SGGPGTKPLRHQ 251
SP VP + + + P P A P+ SS GPG++ L +
Sbjct: 139 VVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQ-LNTK 197
Query: 252 ASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTK 311
+SF V S P W + + R Y F S S ++G A+ +
Sbjct: 198 LQKAQSFDVA------SVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQ 251
Query: 312 SKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAA 371
S L +L+ IW LSD D DG LT EF A HLI +G P LPP L PEY+ +
Sbjct: 252 SSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQP----LPPVLPPEYIPPS 307
Query: 372 F 372
F
Sbjct: 308 F 308
>gi|21264315 EH-domain containing 4 [Homo sapiens]
Length = 541
Score = 67.4 bits (163), Expect = 4e-11
Identities = 41/103 (39%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 272 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 331
+E W + ++ + Y F +L P ISG AK SKL L IW+L+D DCD
Sbjct: 439 EEEWVVAKD-KPVYDELFYTLSPINGK-ISGVNAKKEMVTSKLPNSVLGKIWKLADCDCD 496
Query: 332 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPK 374
G L EF A HLI + +GY LP LPP L P + + PK
Sbjct: 497 GMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPK 539
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 66.6 bits (161), Expect = 7e-11
Identities = 82/366 (22%), Positives = 143/366 (39%), Gaps = 59/366 (16%)
Query: 67 TATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVR 126
T A A + S LP L +I +L G +F++AL+L+A AQ+GL V
Sbjct: 31 TGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS 90
Query: 127 IESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKV-QIPYLTTEKNSFKRMDDEDKQETQ 185
+ S+ +P PRF + + P + GT ++P+ + +D+ K +
Sbjct: 91 LSSLNLAVPPPRFHDTSS--------PLLISGTSAAELPWAV-------KPEDKAKYDAI 135
Query: 186 SPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLV------QPEGSS 239
++SP+ +G+ S +++ P ++ P+ +
Sbjct: 136 FDSLSPV----------------NGFL----SGDKVKPVLLNSKLPVDILGRVWELSDID 175
Query: 240 SGGPGTKPLRHQASLIRSFSVERELQDNSSYPD-------EPWRITEEQREYYVNQFRSL 292
G + A + ++E+E S P + W ++ ++ Y F
Sbjct: 176 HDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTWVVSPAEKAKYDEIFLKT 235
Query: 293 QPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARK-N 351
D F+SG + F K+ L L++IW L D G L+ +F AFHLI +
Sbjct: 236 DKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQFALAFHLISQKLIK 295
Query: 352 GYPLPEGLPPTLQPEYLQAAFPK------PKWDCQLFDSYSESLPANQQPRDLNRMEKTS 405
G P L P + P +A+ K P D F + E N + DL R +
Sbjct: 296 GIDPPHVLTPEMIPPSDRASLQKNIIGSSPVAD---FSAIKELDTLNNEIVDLQREKNNV 352
Query: 406 VKDMAD 411
+D+ +
Sbjct: 353 EQDLKE 358
Score = 39.3 bits (90), Expect = 0.012
Identities = 38/155 (24%), Positives = 55/155 (35%), Gaps = 9/155 (5%)
Query: 285 YVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFH 344
Y +R + + + S A F KS L L IW+L+D D G L EF A
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 345 LIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKT 404
L+ +NG + L A P P++ A + P + +K
Sbjct: 79 LVACAQNGL--------EVSLSSLNLAVPPPRFHDTSSPLLISGTSAAELPWAVKPEDKA 130
Query: 405 SVKDMADLPVPNQDVTSDDKQALKSTINEALPKDV 439
+ D P S DK +N LP D+
Sbjct: 131 KYDAIFDSLSPVNGFLSGDK-VKPVLLNSKLPVDI 164
Score = 31.2 bits (69), Expect = 3.2
Identities = 51/214 (23%), Positives = 81/214 (37%), Gaps = 16/214 (7%)
Query: 75 VADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ-SGL-PVRIESIKC 132
V ++F + LP+ L I LC K G QF +A LI+ G+ P + + +
Sbjct: 248 VREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEM 307
Query: 133 ELPLPRFMMSKN----DGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPT 188
P R + KN F EL +I L EKN+ ++D +E +
Sbjct: 308 IPPSDRASLQKNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNV----EQDLKEKEDTI 363
Query: 189 MSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGGPGTKPL 248
+ QR + KL++ +Q+ E + Q E K
Sbjct: 364 KQRTSEVQDLQDEVQRE--NTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK--EVRKKC 419
Query: 249 RHQASLIRSFSVERELQDN--SSYPDEPWRITEE 280
+A LI S E Q++ S+Y +E + EE
Sbjct: 420 AEEAQLISSLKAELTSQESQISTYEEELAKAREE 453
Score = 30.4 bits (67), Expect = 5.4
Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 20/130 (15%)
Query: 511 LPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFR 570
LPP P RPCP LP R+ ++ P K + + P ++
Sbjct: 771 LPPKIGTPTRPCP-----------LPPGKRSINKLDSPDPFKLNDPFQPFPGNDSPKEKD 819
Query: 571 PE---NQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLAR 627
PE + T + + P++ A +P+ + K+ +E LAR
Sbjct: 820 PEIFCDPFTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKR------ESEREEEQRLAR 873
Query: 628 LNSELQQQLK 637
LN + Q+ L+
Sbjct: 874 LNQQEQEDLE 883
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 64.3 bits (155), Expect = 3e-10
Identities = 47/156 (30%), Positives = 65/156 (41%), Gaps = 13/156 (8%)
Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334
W + E++ + F SL P + +SG K SKL + L +W+LSD D DG L
Sbjct: 121 WAVRVEEKAKFDGIFESLLPI-NGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHL 179
Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQ 394
EF A HL+ P+P LPP+L P K +F LPA+
Sbjct: 180 DRDEFAVAMHLVYRALEKEPVPSALPPSL--------IPPSKRKKTVFPGAVPVLPASPP 231
Query: 395 PRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKST 430
P+D R S + N + K +LK T
Sbjct: 232 PKDSLR----STPSHGSVSSLNSTGSLSPKHSLKQT 263
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/73 (31%), Positives = 36/73 (49%)
Query: 67 TATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVR 126
T A A + S L L +I +L + G+ FY+AL+L+A AQSG V
Sbjct: 31 TGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT 90
Query: 127 IESIKCELPLPRF 139
+ ++ +P P+F
Sbjct: 91 LSNLNLSMPPPKF 103
Score = 39.3 bits (90), Expect = 0.012
Identities = 66/279 (23%), Positives = 104/279 (37%), Gaps = 52/279 (18%)
Query: 285 YVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFH 344
Y + ++ + P + + S A F KS LS L IW+L+D + G L F A
Sbjct: 19 YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78
Query: 345 LIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESL----PANQQPRDLNR 400
L+ ++G+ + TL L + P PK F S L P+ + +
Sbjct: 79 LVACAQSGHEV------TL--SNLNLSMPPPK-----FHDTSSPLMVTPPSAEAHWAVRV 125
Query: 401 MEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALP----------KDVSEDPATPKDSN 450
EK + + +P + S DK +N LP D+ +D +D
Sbjct: 126 EEKAKFDGIFESLLPINGLLSGDK-VKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEF 184
Query: 451 SLKARPRSRSYSSTSIEEAMKRGEDPPT--PPPRPQKTHSRASSLDLNKVFQPSVPATKS 508
++ R+ + A+ PP+ PP + +KT VF +VP +
Sbjct: 185 AVAMHLVYRALEKEPVPSAL-----PPSLIPPSKRKKT-----------VFPGAVPVLPA 228
Query: 509 GLLPPPPALPPRPCPSQ---SEQVSEAELLPQLSRAPSQ 544
PPP R PS S S L P+ S +Q
Sbjct: 229 S---PPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQ 264
Score = 38.9 bits (89), Expect = 0.015
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 1/96 (1%)
Query: 271 PDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADC 330
P W + + + F D ++SG K F S L+ L++IW L+D
Sbjct: 265 PTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQ 324
Query: 331 DGALTLPEFCAAFHLIVAR-KNGYPLPEGLPPTLQP 365
G L+ +F A + I + G P+ L P + P
Sbjct: 325 TGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP 360
>gi|21361462 EH-domain containing 2 [Homo sapiens]
Length = 543
Score = 60.8 bits (146), Expect = 4e-09
Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 16/176 (9%)
Query: 203 QRVPLSHGYSKLRS-------SAEQMHPAPYEARQPLVQPEGSSSGGPGTKPLRHQASLI 255
Q + ++H ++K S + ++M PL++ E S G + + + +
Sbjct: 360 QELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHM 419
Query: 256 RSFSVER------ELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFF 309
F VER E + S + W +T+++ +Y F +L P +SGS AK +
Sbjct: 420 GPF-VERGPDEAMEDGEEGSDDEAEWVVTKDKSKYD-EIFYNLAPADGK-LSGSKAKTWM 476
Query: 310 TKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365
+KL L IW+LSD D DG L EF A HLI A+ G+ LP LP L P
Sbjct: 477 VGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVP 532
>gi|30240932 EH-domain containing 1 [Homo sapiens]
Length = 534
Score = 57.4 bits (137), Expect = 4e-08
Identities = 37/94 (39%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 272 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 331
D W + + + Y F +L P + I+G+ AK KSKL L IW+L+D D D
Sbjct: 436 DVEW-VVGKDKPTYDEIFYTLSP-VNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKD 493
Query: 332 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365
G L EF A HLI + G+ LP LPP L P
Sbjct: 494 GLLDDEEFALANHLIKVKLEGHELPADLPPHLVP 527
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 57.0 bits (136), Expect = 5e-08
Identities = 59/246 (23%), Positives = 97/246 (39%), Gaps = 27/246 (10%)
Query: 390 PANQQPRDLNRME-KTSVKDMADLPVPNQDVTSDDKQALKSTINE---ALPKDVSED--- 442
P NQ+ + R+ + + ++DL ++ +++K L+ + E + +DV+ D
Sbjct: 232 PRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGP 291
Query: 443 ----PAT---PKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDL 495
PA P + + +AR + S + S+EE GEDP + P P+
Sbjct: 292 EPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPE----------- 340
Query: 496 NKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDV 555
+ +P T P PP PP P P +Q EA + A +A E A +DV
Sbjct: 341 --LAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDV 398
Query: 556 LYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAI 615
P + P PE E +A GP + + PT ++K A
Sbjct: 399 ASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAP 458
Query: 616 RKNKEA 621
+EA
Sbjct: 459 EPEREA 464
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 54.7 bits (130), Expect = 3e-07
Identities = 110/511 (21%), Positives = 177/511 (34%), Gaps = 110/511 (21%)
Query: 178 DEDKQETQSPTMS-PLASPPSSPPH--YQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQ 234
D + SP +S P PP SP H Q +P + G SK+
Sbjct: 191 DSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVH------------------- 231
Query: 235 PEGSSSGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRIT-------------EEQ 281
GSS+ G P + L + QD+ P +P T +++
Sbjct: 232 --GSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQK 289
Query: 282 REYYVNQFRSLQPDPSSF-----ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTL 336
YV PS + + F K+ L +P + + +L T
Sbjct: 290 PTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTY 349
Query: 337 P-EFCAAFHLIVARKNGYPLPEGL---PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPAN 392
E ++ + +P P P T +P + FP P D Q + S+ N
Sbjct: 350 SNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEP----SKFPFPTKDSQ----HVSSVTQN 401
Query: 393 QQPRDL------NRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSE---DP 443
Q+ D N + TS DL + + + SD +Q + + + P + +P
Sbjct: 402 QKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSE-DSDSEQTPEKPPSSSAPPSAPQSLPEP 460
Query: 444 ATPKDSNSLKARPRSRSYSSTSIEEAMKRGE-------DPPTPPPRPQKTHSRASSLDLN 496
S+S ++ S S SS+ E + + P P P P T+ L
Sbjct: 461 VASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLT 520
Query: 497 KVFQPSVPATKSGLLPPPPALPPRPCPSQ---SEQVSEAELLPQLS-----RAPSQA--- 545
KV QP+ P PP P S S++ SE++ P S RAP +A
Sbjct: 521 KVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHP 580
Query: 546 ---------AESSPAKKDVLYSQPPSKPIRRKFRPENQA------------------TEN 578
A+ P ++ + ++ P KP++ R ++ T
Sbjct: 581 GKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSK 640
Query: 579 QEPSTAASG-PASAATMKPHPTVQKQSSKQK 608
+P G P +AA+ +P P V S K+K
Sbjct: 641 DKPKVKTKGRPRAAASNEPKPAVPPSSEKKK 671
Score = 35.4 bits (80), Expect = 0.17
Identities = 50/244 (20%), Positives = 94/244 (38%), Gaps = 44/244 (18%)
Query: 434 ALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPP-TPPPRPQKTHSRASS 492
+LP V P +P SN + PR++ S +G P +P K H + +
Sbjct: 203 SLPSPVP--PLSPIHSNQ-QTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETP 259
Query: 493 LDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAE----- 547
D + P+ P +++ PPP+LP + Q + + + +APS++ E
Sbjct: 260 QD--SLVAPAQPPSQTF---PPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLP 314
Query: 548 -------------SSPAKKDVLYSQPPSKPIRRKFRPENQATEN---------QEPSTAA 585
PAK + + PS+ + + + E E P TA
Sbjct: 315 EDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAI 374
Query: 586 SGPASAATMK-PHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERI 644
P++A K P PT Q +++ +N++ ++ +S QQ + ++ +
Sbjct: 375 HTPSTAEPSKFPFPTKDSQH-------VSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL 427
Query: 645 ALEN 648
L +
Sbjct: 428 QLSD 431
Score = 35.4 bits (80), Expect = 0.17
Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 30/251 (11%)
Query: 363 LQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP----NQD 418
+Q + + P P D +L P P + M K ++ ++ +P P ++
Sbjct: 730 VQEDSRKDRLPLPLRDTKLLS------PLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQ 783
Query: 419 VTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPT 478
++DKQ A K SE ++ DS+S A+ R + ++ ++ +
Sbjct: 784 RKAEDKQP------PAGKKHSSEKRSS--DSSSKLAKKRKGEAERDCDNKKIRLEKEIKS 835
Query: 479 PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQL 538
+H +S K +PS ++K +LPPPP S S Q L +
Sbjct: 836 QSSSSSSSHKESSK---TKPSRPSSQSSKKEMLPPPPV-------SSSSQKPAKPALKRS 885
Query: 539 SRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHP 598
R + P S I ++ R E + + + +SG A P P
Sbjct: 886 RREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSG--DTANPFPVP 943
Query: 599 TVQKQSSKQKK 609
++ +SK K
Sbjct: 944 SLPNGNSKPGK 954
Score = 32.7 bits (73), Expect = 1.1
Identities = 100/483 (20%), Positives = 172/483 (35%), Gaps = 60/483 (12%)
Query: 177 DDEDKQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPE 236
D ED Q+P P +S P S P P++ +S SSAE + ++ + E
Sbjct: 431 DSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHS---SSAESESTSDSDSSSD-SESE 486
Query: 237 GSSSGGPGTKPLRHQASLIRSFSVERELQDN-------SSYPDEPWRITEEQREYYVNQF 289
SSS +PL A + + DN + P E R TE R + ++
Sbjct: 487 SSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKG 546
Query: 290 RSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVAR 349
S D ++ S +K+ KS P +A G + + A +
Sbjct: 547 SS---DSATSQEHSESKDPPPKSSSKAPRAP-----PEAPHPGKRSCQKSPAQQEPPQRQ 598
Query: 350 KNGYPLPE---------GLPPTLQPEYLQAAFPKPKWDCQLFDS---YSESLP---ANQQ 394
G P+ G +LQ E P D D ++ P A+ +
Sbjct: 599 TVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNE 658
Query: 395 PRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 454
P+ K + LP P++ ++ + K + + P+ + P T +
Sbjct: 659 PKPAVPPSSEKKKHKSSLPAPSKALSG--PEPAKDNVEDRTPEHFALVPLTES-----QG 711
Query: 455 RPRSRSYSSTS-------IEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATK 507
P S S S TS ++E ++ P P R K S + +
Sbjct: 712 PPHSGSGSRTSGCRQAVVVQEDSRKDRLP--LPLRDTKLLSPLRDTPPPQSLMVKITLDL 769
Query: 508 SGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRR 567
+P PP R ++ +Q + R+ +++ + +K +K IR
Sbjct: 770 LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRL 829
Query: 568 KFRPENQATEN-----QEPSTAASGPASAATMK---PHPTVQKQSSKQKKAIQTAIRKNK 619
+ ++Q++ + + T S P+S ++ K P P V SS QK A R +
Sbjct: 830 EKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPV--SSSSQKPAKPALKRSRR 887
Query: 620 EAN 622
EA+
Sbjct: 888 EAD 890
>gi|7657056 EH-domain containing 3 [Homo sapiens]
Length = 535
Score = 53.5 bits (127), Expect = 6e-07
Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Query: 272 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 331
D W + + + Y F +L P I+G+ AK +SKL L IW+L+D D D
Sbjct: 436 DAEWVVARD-KPMYDEIFYTLSPVDGK-ITGANAKKEMVRSKLPNSVLGKIWKLADIDKD 493
Query: 332 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365
G L EF A HLI + G+ LP LP L P
Sbjct: 494 GMLDDDEFALANHLIKVKLEGHELPNELPAHLLP 527
>gi|24497554 homeobox A13 [Homo sapiens]
Length = 388
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/98 (39%), Positives = 41/98 (41%), Gaps = 22/98 (22%)
Query: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEG----------------EQQCY------ 38
ME AAAAAAAAAAAAAAG G G P P + G QC
Sbjct: 35 MEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHP 94
Query: 39 SELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVA 76
+ L A A PG PP AA A A AAA A
Sbjct: 95 APLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAA 132
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/104 (37%), Positives = 47/104 (45%), Gaps = 25/104 (24%)
Query: 3 AAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAA--GGGP------- 53
AAAAAAAAAAAAAAA G GP +E +QC + C+ AA GP
Sbjct: 119 AAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQC-----SPCSAAAQSSSGPAALPYGY 173
Query: 54 -GSGPPEAARVAP----------GTATAAAGPVADLFRASQLPA 86
GSG AR+ P + AAA AD + + PA
Sbjct: 174 FGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPA 217
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.1 bits (118), Expect = 7e-06
Identities = 44/200 (22%), Positives = 75/200 (37%), Gaps = 26/200 (13%)
Query: 417 QDVTSDDKQALKSTINEALPKDVSEDPATPK-------------DSNSLKARPRSRSYSS 463
++V + A + +N P+D + P TP ++ + P + + +
Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAP 202
Query: 464 TSIEEAMKRGEDPPTPP---PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPP-ALPP 519
S + PPTPP P P + + + + PA S PP A+PP
Sbjct: 203 PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPP 262
Query: 520 RPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQ 579
P + + S A P+ + AP + ++PA PPS P ++ T N
Sbjct: 263 TPSATTLDP-SSASAPPETTAAPPTPSATTPA--------PPSSPAPQETTAAPITTPNS 313
Query: 580 EPSTAASGPASAATMKPHPT 599
P+T A + + H T
Sbjct: 314 SPTTLAPDTSETSAAPTHQT 333
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.1 bits (118), Expect = 7e-06
Identities = 44/200 (22%), Positives = 75/200 (37%), Gaps = 26/200 (13%)
Query: 417 QDVTSDDKQALKSTINEALPKDVSEDPATPK-------------DSNSLKARPRSRSYSS 463
++V + A + +N P+D + P TP ++ + P + + +
Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAP 202
Query: 464 TSIEEAMKRGEDPPTPP---PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPP-ALPP 519
S + PPTPP P P + + + + PA S PP A+PP
Sbjct: 203 PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPP 262
Query: 520 RPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQ 579
P + + S A P+ + AP + ++PA PPS P ++ T N
Sbjct: 263 TPSATTLDP-SSASAPPETTAAPPTPSATTPA--------PPSSPAPQETTAAPITTPNS 313
Query: 580 EPSTAASGPASAATMKPHPT 599
P+T A + + H T
Sbjct: 314 SPTTLAPDTSETSAAPTHQT 333
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.1 bits (118), Expect = 7e-06
Identities = 44/200 (22%), Positives = 75/200 (37%), Gaps = 26/200 (13%)
Query: 417 QDVTSDDKQALKSTINEALPKDVSEDPATPK-------------DSNSLKARPRSRSYSS 463
++V + A + +N P+D + P TP ++ + P + + +
Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAP 202
Query: 464 TSIEEAMKRGEDPPTPP---PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPP-ALPP 519
S + PPTPP P P + + + + PA S PP A+PP
Sbjct: 203 PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPP 262
Query: 520 RPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQ 579
P + + S A P+ + AP + ++PA PPS P ++ T N
Sbjct: 263 TPSATTLDP-SSASAPPETTAAPPTPSATTPA--------PPSSPAPQETTAAPITTPNS 313
Query: 580 EPSTAASGPASAATMKPHPT 599
P+T A + + H T
Sbjct: 314 SPTTLAPDTSETSAAPTHQT 333
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 49.7 bits (117), Expect = 9e-06
Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%)
Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435
++ +EKTS KD+A L P + + K+ +T E
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233
Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492
P + P TPK+ A ++S +T E A ++P PT P P P T A +
Sbjct: 234 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289
Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535
+ P PA + P P P P P P+ E + E
Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349
Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585
P + P+ PA P P +P + T+ P+T
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409
Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617
S P + P T + + K+ T +K
Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 441
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%)
Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413
P P +++A PK + + P P T+ K+ A P
Sbjct: 229 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288
Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
+ + K+ +T + P E P TPK+ + + T+ E A
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 344
Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529
++P PT P +P T + + K +P+ TK P P P P P+ +S
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 398
Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588
+ E P ++ AP+ E SP P +P + T + T P
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458
Query: 589 ASAATMKPHPTVQKQ 603
A T KP PT K+
Sbjct: 459 APTTTKKPAPTTPKE 473
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
P + + K+ +T E P P TPK+ P+ + ++ E
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 363
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534
PT P P T ++ S K +P+ TKS P P P ++S + E
Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 418
Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594
P ++ P+ PA P KP + T + T PA
Sbjct: 419 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 472
Query: 595 KPHPTVQKQSS 605
+P PT K+++
Sbjct: 473 EPAPTTPKETA 483
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%)
Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415
PE L PT E +P + + P P T+ K+ A P
Sbjct: 511 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 559
Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
+ + K+ +T P + E P TPK +P + + T+ +E
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 612
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529
D P P P+ T + P T G P P P P +P P
Sbjct: 613 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 666
Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588
EL P ++ P+ PA P+ P E T +EP+ T P
Sbjct: 667 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 708
Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620
A P PT + S+ T I K+ +
Sbjct: 709 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 740
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473
P + + K+ +T E P E P TPK+ A ++S +T+ E A
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 408
Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533
+ PT P P T ++ + K P+ P P P P P P+ ++ +
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 459
Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593
P ++ P+ PA + P + PE A E + A T
Sbjct: 460 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517
Query: 594 MKPHPT 599
PT
Sbjct: 518 TPEEPT 523
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%)
Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
P P+ SD + T+N+ + E T K +++ + + + SIE+ +
Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185
Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527
P + P P+ + T ++ +L K P+ P + P P P +S
Sbjct: 186 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 240
Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586
+ E P ++ AP+ E +P P +P + T P+T
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 587 GPASAATMKPHPTVQKQ 603
PA KP PT K+
Sbjct: 301 -PAPTTPKKPAPTTPKE 316
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%)
Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449
P P T+ K + T+ +K A T E L E+P
Sbjct: 471 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 528
Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509
P++ + ++ E PT P P T + ++ K P+
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 582
Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553
L P P P +P P + + E P + P+ PA
Sbjct: 583 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642
Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605
+ P + P+ A + P+T GP S + KP PT K+++
Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 693
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 49.7 bits (117), Expect = 9e-06
Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%)
Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435
++ +EKTS KD+A L P + + K+ +T E
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274
Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492
P + P TPK+ A ++S +T E A ++P PT P P P T A +
Sbjct: 275 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330
Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535
+ P PA + P P P P P P+ E + E
Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390
Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585
P + P+ PA P P +P + T+ P+T
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450
Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617
S P + P T + + K+ T +K
Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 482
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%)
Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413
P P +++A PK + + P P T+ K+ A P
Sbjct: 270 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329
Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
+ + K+ +T + P E P TPK+ + + T+ E A
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 385
Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529
++P PT P +P T + + K +P+ TK P P P P P+ +S
Sbjct: 386 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 439
Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588
+ E P ++ AP+ E SP P +P + T + T P
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 589 ASAATMKPHPTVQKQ 603
A T KP PT K+
Sbjct: 500 APTTTKKPAPTTPKE 514
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
P + + K+ +T E P P TPK+ P+ + ++ E
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 404
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534
PT P P T ++ S K +P+ TKS P P P ++S + E
Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 459
Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594
P ++ P+ PA P KP + T + T PA
Sbjct: 460 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 513
Query: 595 KPHPTVQKQSS 605
+P PT K+++
Sbjct: 514 EPAPTTPKETA 524
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%)
Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415
PE L PT E +P + + P P T+ K+ A P
Sbjct: 552 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 600
Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
+ + K+ +T P + E P TPK +P + + T+ +E
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 653
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529
D P P P+ T + P T G P P P P +P P
Sbjct: 654 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 707
Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588
EL P ++ P+ PA P+ P E T +EP+ T P
Sbjct: 708 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 749
Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620
A P PT + S+ T I K+ +
Sbjct: 750 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 781
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473
P + + K+ +T E P E P TPK+ A ++S +T+ E A
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 449
Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533
+ PT P P T ++ + K P+ P P P P P P+ ++ +
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 500
Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593
P ++ P+ PA + P + PE A E + A T
Sbjct: 501 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558
Query: 594 MKPHPT 599
PT
Sbjct: 559 TPEEPT 564
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%)
Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
P P+ SD + T+N+ + E T K +++ + + + SIE+ +
Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226
Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527
P + P P+ + T ++ +L K P+ P + P P P +S
Sbjct: 227 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 281
Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586
+ E P ++ AP+ E +P P +P + T P+T
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 587 GPASAATMKPHPTVQKQ 603
PA KP PT K+
Sbjct: 342 -PAPTTPKKPAPTTPKE 357
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%)
Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449
P P T+ K + T+ +K A T E L E+P
Sbjct: 512 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 569
Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509
P++ + ++ E PT P P T + ++ K P+
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 623
Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553
L P P P +P P + + E P + P+ PA
Sbjct: 624 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683
Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605
+ P + P+ A + P+T GP S + KP PT K+++
Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 734
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 49.7 bits (117), Expect = 9e-06
Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%)
Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435
++ +EKTS KD+A L P + + K+ +T E
Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 326
Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492
P + P TPK+ A ++S +T E A ++P PT P P P T A +
Sbjct: 327 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382
Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535
+ P PA + P P P P P P+ E + E
Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442
Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585
P + P+ PA P P +P + T+ P+T
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617
S P + P T + + K+ T +K
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 534
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%)
Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413
P P +++A PK + + P P T+ K+ A P
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381
Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
+ + K+ +T + P E P TPK+ + + T+ E A
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 437
Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529
++P PT P +P T + + K +P+ TK P P P P P+ +S
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 491
Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588
+ E P ++ AP+ E SP P +P + T + T P
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551
Query: 589 ASAATMKPHPTVQKQ 603
A T KP PT K+
Sbjct: 552 APTTTKKPAPTTPKE 566
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
P + + K+ +T E P P TPK+ P+ + ++ E
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 456
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534
PT P P T ++ S K +P+ TKS P P P ++S + E
Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 511
Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594
P ++ P+ PA P KP + T + T PA
Sbjct: 512 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565
Query: 595 KPHPTVQKQSS 605
+P PT K+++
Sbjct: 566 EPAPTTPKETA 576
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%)
Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415
PE L PT E +P + + P P T+ K+ A P
Sbjct: 604 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 652
Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
+ + K+ +T P + E P TPK +P + + T+ +E
Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 705
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529
D P P P+ T + P T G P P P P +P P
Sbjct: 706 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 759
Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588
EL P ++ P+ PA P+ P E T +EP+ T P
Sbjct: 760 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 801
Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620
A P PT + S+ T I K+ +
Sbjct: 802 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 833
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473
P + + K+ +T E P E P TPK+ A ++S +T+ E A
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 501
Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533
+ PT P P T ++ + K P+ P P P P P P+ ++ +
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 552
Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593
P ++ P+ PA + P + PE A E + A T
Sbjct: 553 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 610
Query: 594 MKPHPT 599
PT
Sbjct: 611 TPEEPT 616
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%)
Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
P P+ SD + T+N+ + E T K +++ + + + SIE+ +
Sbjct: 219 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278
Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527
P + P P+ + T ++ +L K P+ P + P P P +S
Sbjct: 279 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 333
Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586
+ E P ++ AP+ E +P P +P + T P+T
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393
Query: 587 GPASAATMKPHPTVQKQ 603
PA KP PT K+
Sbjct: 394 -PAPTTPKKPAPTTPKE 409
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%)
Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449
P P T+ K + T+ +K A T E L E+P
Sbjct: 564 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 621
Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509
P++ + ++ E PT P P T + ++ K P+
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 675
Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553
L P P P +P P + + E P + P+ PA
Sbjct: 676 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735
Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605
+ P + P+ A + P+T GP S + KP PT K+++
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 786
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 49.7 bits (117), Expect = 9e-06
Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%)
Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435
++ +EKTS KD+A L P + + K+ +T E
Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 367
Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492
P + P TPK+ A ++S +T E A ++P PT P P P T A +
Sbjct: 368 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423
Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535
+ P PA + P P P P P P+ E + E
Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585
P + P+ PA P P +P + T+ P+T
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617
S P + P T + + K+ T +K
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 575
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%)
Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413
P P +++A PK + + P P T+ K+ A P
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422
Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
+ + K+ +T + P E P TPK+ + + T+ E A
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 478
Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529
++P PT P +P T + + K +P+ TK P P P P P+ +S
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 532
Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588
+ E P ++ AP+ E SP P +P + T + T P
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592
Query: 589 ASAATMKPHPTVQKQ 603
A T KP PT K+
Sbjct: 593 APTTTKKPAPTTPKE 607
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
P + + K+ +T E P P TPK+ P+ + ++ E
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 497
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534
PT P P T ++ S K +P+ TKS P P P ++S + E
Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 552
Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594
P ++ P+ PA P KP + T + T PA
Sbjct: 553 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606
Query: 595 KPHPTVQKQSS 605
+P PT K+++
Sbjct: 607 EPAPTTPKETA 617
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%)
Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415
PE L PT E +P + + P P T+ K+ A P
Sbjct: 645 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 693
Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474
+ + K+ +T P + E P TPK +P + + T+ +E
Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 746
Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529
D P P P+ T + P T G P P P P +P P
Sbjct: 747 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 800
Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588
EL P ++ P+ PA P+ P E T +EP+ T P
Sbjct: 801 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 842
Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620
A P PT + S+ T I K+ +
Sbjct: 843 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 874
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%)
Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473
P + + K+ +T E P E P TPK+ A ++S +T+ E A
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 542
Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533
+ PT P P T ++ + K P+ P P P P P P+ ++ +
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 593
Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593
P ++ P+ PA + P + PE A E + A T
Sbjct: 594 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 651
Query: 594 MKPHPT 599
PT
Sbjct: 652 TPEEPT 657
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%)
Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472
P P+ SD + T+N+ + E T K +++ + + + SIE+ +
Sbjct: 260 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319
Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527
P + P P+ + T ++ +L K P+ P + P P P +S
Sbjct: 320 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 374
Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586
+ E P ++ AP+ E +P P +P + T P+T
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434
Query: 587 GPASAATMKPHPTVQKQ 603
PA KP PT K+
Sbjct: 435 -PAPTTPKKPAPTTPKE 450
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%)
Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449
P P T+ K + T+ +K A T E L E+P
Sbjct: 605 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 662
Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509
P++ + ++ E PT P P T + ++ K P+
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 716
Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553
L P P P +P P + + E P + P+ PA
Sbjct: 717 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776
Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605
+ P + P+ A + P+T GP S + KP PT K+++
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 827
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/267 (24%), Positives = 99/267 (37%), Gaps = 28/267 (10%)
Query: 411 DLPVPNQDVTSDDKQALKSTIN-------EALP--KDVSEDPATPKDSNSLKARPRSRSY 461
+LP P+ V Q ST + E +P K+ S + + K+ K RPRSRS
Sbjct: 222 ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSR 281
Query: 462 SSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPA-----TKSGLLPPPPA 516
S + + R P PR ++ SR+ S + P T +PPPP
Sbjct: 282 SKS---RSRTRSRSPSHTRPR-RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
Query: 517 LPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSK---------PIRR 567
P + + S A L S + S + S P K S PP K P RR
Sbjct: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397
Query: 568 KFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLAR 627
+ RP AT + + + S T K +V + K K + +
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
Query: 628 LNSELQQQLKEVHQERIALENQLEQLR 654
EL + +E ++A + ++Q R
Sbjct: 458 RKVELSES-EEDKGGKMAAADSVQQRR 483
Score = 44.7 bits (104), Expect = 3e-04
Identities = 53/213 (24%), Positives = 77/213 (36%), Gaps = 19/213 (8%)
Query: 428 KSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-----PTPPPR 482
K ++ + P P T + S SL ++ R S S S EA R P P+P PR
Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA--RSPQPNKRHSPSPRPR 689
Query: 483 PQKTHS------RASSLDLNKVFQPSV---PATKSGLLPPPPALPPRPCPSQSEQVSEAE 533
+T S R +S + PS P + P P + PS + V
Sbjct: 690 APQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP-QSVRRVS 748
Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593
+S +P AA+ PA + SQ PS + + PS +
Sbjct: 749 SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGG 808
Query: 594 MKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626
K K+ K KK +K+K+ AV A
Sbjct: 809 KKKKKKKDKKHKKDKK--HKKHKKHKKEKAVAA 839
Score = 43.5 bits (101), Expect = 6e-04
Identities = 100/474 (21%), Positives = 165/474 (34%), Gaps = 69/474 (14%)
Query: 169 EKNSFKRMDDE-----DKQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHP 223
EKNS K + E + ++S + + SP + P + S YS R + + P
Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321
Query: 224 APYEARQPLVQP---EGSSSGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEE 280
+P P P S P + R ASL S S + S P R +
Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
Query: 281 QREYYVNQFRSLQPD---PSSFISGSVAKNFFTKSKLS-IPELSYIWELSDADCDGALTL 336
R+ R L P P S K++ S P+ S S T
Sbjct: 382 PRKT-----RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS 436
Query: 337 PEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPR 396
+ V + G E P +P ++ + + ++ + S QQ R
Sbjct: 437 GK--------VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV-----QQRR 483
Query: 397 DLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTI-NEALPKDVSEDPATPKDSNSLKAR 455
R + S D +S+D++ +S + N + + P+ + K +
Sbjct: 484 QYRRQNQQSSSDSGS------SSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQ 537
Query: 456 ----PRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLL 511
PR R S S +R P PPPR ++T P+ P +
Sbjct: 538 KETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT--------------PTPPPRRRTPS 583
Query: 512 PPPPALPPRP---CPSQSEQVSEAELLPQLSRAP-----SQAAESSPAKKDVLYSQPP-- 561
PPP P P P + S + + + +P +A+ S P K+ V +S PP
Sbjct: 584 PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQ 643
Query: 562 -SKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTA 614
S P+ ++ P + + S + S + P P + S + +A QT+
Sbjct: 644 RSSPVTKRRSPSLSSKHRKGSSPSRS---TREARSPQPNKRHSPSPRPRAPQTS 694
Score = 34.7 bits (78), Expect = 0.29
Identities = 53/238 (22%), Positives = 96/238 (40%), Gaps = 34/238 (14%)
Query: 409 MADLPVPNQDVTSDDKQALKSTINEA----LPKDVSEDPATPKDSNSLKARPRSRSYSST 464
+A + ++D DK+ +S+ + P+ +P+ +S R R RS+S +
Sbjct: 141 LASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRS 200
Query: 465 SIEEAMKRGEDPPTPPPRPQKTHSRASSLDLN-KVFQPSVP---ATKSGLLPPPPALPPR 520
R +P P P+K + + KV +PSV +T L P P P
Sbjct: 201 PRHRTKSR-----SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE 255
Query: 521 PCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPS--KPIR------RKFRPE 572
P E+ S+ E + +R S++ S ++ S+ PS +P R R + P
Sbjct: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSR---TRSRSPSHTRPRRRHRSRSRSYSPR 312
Query: 573 NQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNS 630
+ + + PS P M P P ++ S +R+ + ++A L+ +S
Sbjct: 313 RRPSPRRRPSPRRRTP--PRRMPPPPRHRRSRS--------PVRRRRRSSASLSGSSS 360
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/209 (22%), Positives = 72/209 (34%), Gaps = 4/209 (1%)
Query: 386 SESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPAT 445
S SL ++ P S + P QAL+ + P PA
Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPAL 287
Query: 446 PKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPA 505
S+S A P + S S +++ PP PP T + +L F PS P
Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347
Query: 506 TKSGLLPP--PPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSK 563
+ PP PPAL P + + L P + +P + +S PPS
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407
Query: 564 PIRRKFRPENQATENQEPSTAASGPASAA 592
P++ F P + + + P S A
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLA 436
Score = 33.1 bits (74), Expect = 0.84
Identities = 40/161 (24%), Positives = 55/161 (34%), Gaps = 28/161 (17%)
Query: 473 GEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEA 532
G P TP P + SRA+ ++ +P P PP PR S + + S
Sbjct: 157 GPTPGTPSPAMAR-RSRAAGTEVG------LPRPAPSARPRPPTEGPRKSVSSASEHSTT 209
Query: 533 ELLPQLSRAPSQAAE-SSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASA 591
E P R PS PA + + S P S A SGP++
Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLS------------------SPARSGPSAR 251
Query: 592 ATMK--PHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNS 630
T + HP+ K Q K+A L L+S
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292
Score = 32.7 bits (73), Expect = 1.1
Identities = 38/166 (22%), Positives = 52/166 (31%), Gaps = 14/166 (8%)
Query: 445 TPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKV------ 498
+P+ N+L +S P +PP P T + L
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 444
Query: 499 FQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAK--KDVL 556
P+ P PPP A PP P + P L+ P QA S PA
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504
Query: 557 YSQPPSKPIRRKFRPENQATE------NQEPSTAASGPASAATMKP 596
+S S P+ P QA Q P + + P A +P
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550
Score = 29.6 bits (65), Expect = 9.2
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 182 QETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSG 241
Q SP SP SP ++PP PL+ +L Q PA A PL +
Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA--LATPPLQALPSPPAS 498
Query: 242 GPGTKPLRHQASL 254
PG P ASL
Sbjct: 499 FPGQAPFSPSASL 511
>gi|163659920 pannexin 2 isoform 1 [Homo sapiens]
Length = 677
Score = 48.1 bits (113), Expect = 3e-05
Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 23/204 (11%)
Query: 435 LPKDVSEDPATPKDSNSLKARP---RSRSYSSTSIEEAMKR--------GEDP------- 476
LP+ E A + NS +P R ++ + T I + R G DP
Sbjct: 439 LPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPA 498
Query: 477 PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLP 536
P PPP P K H+R SLD++ P + TK PA P + +S+AE
Sbjct: 499 PAPPPAPDKKHARHFSLDVH----PYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDC- 553
Query: 537 QLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKP 596
L AP+ ++ +K++ Y P++ P + + P+ A PAS +P
Sbjct: 554 GLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613
Query: 597 HPTVQKQSSKQKKAIQTAIRKNKE 620
+ + ++ I T +E
Sbjct: 614 LTILSRNATHPLLHINTLYEAREE 637
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 48.1 bits (113), Expect = 3e-05
Identities = 61/219 (27%), Positives = 91/219 (41%), Gaps = 19/219 (8%)
Query: 390 PANQQPRDL-NRMEKTSVKDMADLPVPNQD----VTSDDKQALKST-INEALPKDVSEDP 443
PA DL + K ++ LP P++ TS + +L+ T ++ D+S P
Sbjct: 590 PAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS--P 647
Query: 444 ATPKDSNSLKARPRSRSYSSTSIE--EAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQP 501
+P + S +A+ R ST EA R E PT PP SSLD P
Sbjct: 648 VSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGP 707
Query: 502 SVPATKSGLLPPPPALPPRP-CPSQSEQVSEAELLPQL-SRAPSQAAESSPAKKDVLYSQ 559
P S + PPP PP P PS SE+ S + L P+ +R PS+ ++ A+ + ++
Sbjct: 708 WEPGRGSSMSSPPPLPPPPPMSPSWSER-SVSPLRPETEARPPSRQLQALLARNIINAAR 766
Query: 560 PPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHP 598
R+ P + EN P + P P P
Sbjct: 767 ------RKSASPRSAGAENPRPFSPPRAPPPPPPPPPPP 799
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/154 (25%), Positives = 58/154 (37%), Gaps = 4/154 (2%)
Query: 443 PATPKDSNSL--KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQ 500
PATP S+ A P + S S +++ PP PP T + +L F
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381
Query: 501 PSVPATKSGLLPP--PPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYS 558
PS P + PP PPAL P + + L P + +P + +S
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 559 QPPSKPIRRKFRPENQATENQEPSTAASGPASAA 592
PPS P++ F P + + + P S A
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475
Score = 33.1 bits (74), Expect = 0.84
Identities = 40/161 (24%), Positives = 55/161 (34%), Gaps = 28/161 (17%)
Query: 473 GEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEA 532
G P TP P + SRA+ ++ +P P PP PR S + + S
Sbjct: 166 GPTPGTPSPAMAR-RSRAAGTEVG------LPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 533 ELLPQLSRAPSQAAE-SSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASA 591
E P R PS PA + + S P S A SGP++
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLS------------------SPARSGPSAR 260
Query: 592 ATMK--PHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNS 630
T + HP+ K Q K+A L L+S
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Score = 32.7 bits (73), Expect = 1.1
Identities = 38/166 (22%), Positives = 52/166 (31%), Gaps = 14/166 (8%)
Query: 445 TPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKV------ 498
+P+ N+L +S P +PP P T + L
Sbjct: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483
Query: 499 FQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAK--KDVL 556
P+ P PPP A PP P + P L+ P QA S PA
Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543
Query: 557 YSQPPSKPIRRKFRPENQATE------NQEPSTAASGPASAATMKP 596
+S S P+ P QA Q P + + P A +P
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 589
Score = 29.6 bits (65), Expect = 9.2
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 182 QETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSG 241
Q SP SP SP ++PP PL+ +L Q PA A PL +
Sbjct: 480 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA--LATPPLQALPSPPAS 537
Query: 242 GPGTKPLRHQASL 254
PG P ASL
Sbjct: 538 FPGQAPFSPSASL 550
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,344,335
Number of Sequences: 37866
Number of extensions: 1887865
Number of successful extensions: 21161
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 231
Number of HSP's successfully gapped in prelim test: 1158
Number of HSP's that attempted gapping in prelim test: 14131
Number of HSP's gapped (non-prelim): 6048
length of query: 659
length of database: 18,247,518
effective HSP length: 109
effective length of query: 550
effective length of database: 14,120,124
effective search space: 7766068200
effective search space used: 7766068200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.