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Search of human proteins with 37700249
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens]
(450 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens] 925 0.0
gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens] 896 0.0
gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] 108 1e-23
gi|21314600 carcinoembryonic antigen-related cell adhesion molec... 82 8e-16
gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 82 1e-15
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi... 79 6e-15
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [... 76 7e-14
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1... 75 1e-13
gi|68161541 carcinoembryonic antigen-related cell adhesion molec... 74 3e-13
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 74 3e-13
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 68 1e-11
gi|118572606 hemicentin 1 [Homo sapiens] 68 2e-11
gi|54792136 follistatin-like 4 [Homo sapiens] 67 3e-11
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 66 7e-11
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 66 7e-11
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 66 7e-11
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 66 7e-11
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 65 1e-10
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 65 1e-10
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 65 1e-10
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 65 1e-10
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 65 1e-10
gi|110349719 titin isoform N2-A [Homo sapiens] 64 4e-10
gi|52317156 carcinoembryonic antigen-related cell adhesion molec... 64 4e-10
gi|148612793 carcinoembryonic antigen-related cell adhesion mole... 63 5e-10
gi|85861202 carcinoembryonic antigen-related cell adhesion molec... 63 6e-10
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens] 61 2e-09
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H... 60 3e-09
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [... 60 3e-09
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2... 60 3e-09
>gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens]
Length = 450
Score = 925 bits (2390), Expect = 0.0
Identities = 450/450 (100%), Positives = 450/450 (100%)
Query: 1 MWLKVFTTFLSFATGACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFER 60
MWLKVFTTFLSFATGACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFER
Sbjct: 1 MWLKVFTTFLSFATGACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFER 60
Query: 61 PHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTL 120
PHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTL
Sbjct: 61 PHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTL 120
Query: 121 SASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTS 180
SASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTS
Sbjct: 121 SASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTS 180
Query: 181 STYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGL 240
STYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGL
Sbjct: 181 STYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGL 240
Query: 241 KVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMD 300
KVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMD
Sbjct: 241 KVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMD 300
Query: 301 YVCCAYNNITGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLW 360
YVCCAYNNITGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLW
Sbjct: 301 YVCCAYNNITGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLW 360
Query: 361 KKYQPYKVIKQKLEGRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVP 420
KKYQPYKVIKQKLEGRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVP
Sbjct: 361 KKYQPYKVIKQKLEGRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVP 420
Query: 421 ASDCVSGQDLHSTVYEVIQHIPAQQQDHPE 450
ASDCVSGQDLHSTVYEVIQHIPAQQQDHPE
Sbjct: 421 ASDCVSGQDLHSTVYEVIQHIPAQQQDHPE 450
>gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens]
Length = 462
Score = 896 bits (2316), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 15 GACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNK 74
GACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNK
Sbjct: 27 GACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNK 86
Query: 75 SVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPV 134
SVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPV
Sbjct: 87 SVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPV 146
Query: 135 TKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHI 194
TKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHI
Sbjct: 147 TKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHI 206
Query: 195 APVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAI 254
APVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAI
Sbjct: 207 APVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAI 266
Query: 255 LFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQD 314
LFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQD
Sbjct: 267 LFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQD 326
Query: 315 ETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKVIKQKLE 374
ETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKVIKQKLE
Sbjct: 327 ETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKVIKQKLE 386
Query: 375 GRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVPASDCVSGQDLHSTV 434
GRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVPASDCVSGQDLHSTV
Sbjct: 387 GRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVPASDCVSGQDLHSTV 446
Query: 435 YEVIQHIPAQQQDHPE 450
YEVIQHIPAQQQDHPE
Sbjct: 447 YEVIQHIPAQQQDHPE 462
>gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]
Length = 416
Score = 108 bits (270), Expect = 1e-23
Identities = 72/227 (31%), Positives = 115/227 (50%), Gaps = 10/227 (4%)
Query: 3 LKVFTTFLSFATGACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQII-WLFERP 61
L F L T G+ +T P +HG G++ L V Y + +SD ++ W +R
Sbjct: 17 LAPFVYLLLIQTDPLEGVNITSPVRLIHGTVGKSALLSVQYS--STSSDRPVVKWQLKRD 74
Query: 62 HTMPKYLLGSVNKSVVPDL--EYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGT 119
P ++ S+ V+ L +Y+ + + N SLL++ LQ DEG Y V+++I + T
Sbjct: 75 K--PVTVVQSIGTEVIGTLRPDYRDRIRLFE-NGSLLLSDLQLADEGTYEVEISITDD-T 130
Query: 120 LSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHT 179
+ + I +TVD P+++P V + + +E TL C E GT+ +Y WLK+G+P+
Sbjct: 131 FTGEKTINLTVDVPISRPQVLVASTT-VLELSEAFTLNCSHENGTKPSYTWLKDGKPLLN 189
Query: 180 SSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIY 226
S SP L I V ED YSC+V NP+S+ S + +Y
Sbjct: 190 DSRMLLSPDQKVLTITRVLMEDDDLYSCMVENPISQGRSLPVKITVY 236
>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
8 [Homo sapiens]
Length = 349
Score = 82.4 bits (202), Expect = 8e-16
Identities = 88/329 (26%), Positives = 144/329 (43%), Gaps = 31/329 (9%)
Query: 21 KVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSV--NKSVVP 78
++T+ + + G+ + L VH + P W + ++G V N+ + P
Sbjct: 35 QLTIEAVPSNAAEGKEVLLLVH---NLPQDPRGYNWYKGETVDANRRIIGYVISNQQITP 91
Query: 79 DLEYQHKFTMMPPNASLLINPLQFPDEGNY---IVKVNIQGNGTLSASQKIQVTVDDPVT 135
Y ++ T+ P NASLL+ + D G+Y ++K+N+ +S Q +V
Sbjct: 92 GPAYSNRETIYP-NASLLMRNVTRNDTGSYTLQVIKLNL-----MSEEVTGQFSVHPETP 145
Query: 136 KPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIA 195
KP + + S VE + TC E Y W NG+ + S S N TL +
Sbjct: 146 KPSISSNN-SNPVEDKDAVAFTCEPET-QNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLL 203
Query: 196 PVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVN-SDKGLKVGEVFTVDLGEAI 254
VT+ D+G Y C ++NP S SD + + YGP ++ SD G V+L
Sbjct: 204 SVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAG----VNLN--- 256
Query: 255 LFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQD 314
C A S+PP+ YSW + N T+ ++ +L + + + + Y C N+ TGR +
Sbjct: 257 -LSCHAASNPPSQYSW---SVNGTF-QQYTQKLFIPN-ITTKNSGSYACHTTNSATGR-N 309
Query: 315 ETHFTVIITSVGLEKLAQKGKSLSPLASI 343
T +I S L + + G S SI
Sbjct: 310 RTTVRMITVSDALVQGSSPGLSARATVSI 338
>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
6 (non-specific cross reacting antigen) [Homo sapiens]
Length = 344
Score = 81.6 bits (200), Expect = 1e-15
Identities = 89/328 (27%), Positives = 135/328 (41%), Gaps = 26/328 (7%)
Query: 21 KVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSV--NKSVVP 78
K+T+ S + G+ + L H + P + I W ++G V + P
Sbjct: 35 KLTIESTPFNVAEGKEVLLLAH---NLPQNRIGYSWYKGERVDGNSLIVGYVIGTQQATP 91
Query: 79 DLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPV 138
Y + T+ P NASLLI + D G Y ++V A+ + V + P KP
Sbjct: 92 GPAYSGRETIYP-NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELP--KPS 148
Query: 139 VQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVT 198
+ + S VE + TC E Y W NG+ + S S N TL + V
Sbjct: 149 ISSNN-SNPVEDKDAVAFTCEPEV-QNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVK 206
Query: 199 KEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDC 258
+ D G+Y C ++NP S SD + + YGP G ++ K GE + C
Sbjct: 207 RNDAGSYECEIQNPASANRSDPVTLNVLYGPDGPTISPSKA-------NYRPGENLNLSC 259
Query: 259 SADSHPPNTYSW-IRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITG--RQDE 315
A S+PP YSW I T + P + V + Y+C A+N+ TG R
Sbjct: 260 HAASNPPAQYSWFINGTFQQSTQELFIPNITV------NNSGSYMCQAHNSATGLNRTTV 313
Query: 316 THFTVIITSVGLEKLAQKGKSLSPLASI 343
T TV ++ L +A G ++ LA +
Sbjct: 314 TMITVSGSAPVLSAVATVGITIGVLARV 341
>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
sapiens]
Length = 335
Score = 79.3 bits (194), Expect = 6e-15
Identities = 70/241 (29%), Positives = 105/241 (43%), Gaps = 21/241 (8%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHP--PSGAVE 149
NASLLI + D G+Y + + +G+GT + T+ KP + P A+E
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAME 163
Query: 150 YVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLV 209
V LTC E +YQW NG+ + + + S N TL + VTK G Y C +
Sbjct: 164 TV---ILTCDPETPDT-SYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEI 219
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
RN S SD + + +GP +++ G+ + C A+S+PP YS
Sbjct: 220 RNSGSASRSDPVTLNLLHGPDLPRIHP-------SYTNYRSGDNLYLSCFANSNPPAQYS 272
Query: 270 WIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII---TSVG 326
W T N + + G L + + YVC N+ TG + T TV + T +G
Sbjct: 273 W---TINGKF-QQSGQNLFIPQITTKHSGL-YVCSVRNSATGEESSTSLTVKVSASTRIG 327
Query: 327 L 327
L
Sbjct: 328 L 328
>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
[Homo sapiens]
Length = 326
Score = 75.9 bits (185), Expect = 7e-14
Identities = 67/234 (28%), Positives = 98/234 (41%), Gaps = 18/234 (7%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHP--PSGAVE 149
NASLLI + D G+Y + + + +GT + T+ KP + P A+E
Sbjct: 104 NASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAME 163
Query: 150 YVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLV 209
V LTC +YQW NG+ + + S N TL I VTK G Y C +
Sbjct: 164 AV---ILTCD-PATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEI 219
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
RNPVS SD + + +GP D GE + C A+S+P YS
Sbjct: 220 RNPVSASRSDPVTLNLLHGP-------DLPSIYPSFTYYRSGENLYLSCFAESNPRAQYS 272
Query: 270 WIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIIT 323
W T N + + G +L + + Y C N+ TG++ TV ++
Sbjct: 273 W---TINGKFQLS-GQKLSIPQITTKHSGL-YACSVRNSATGKESSKSITVKVS 321
>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
[Homo sapiens]
Length = 335
Score = 75.1 bits (183), Expect = 1e-13
Identities = 71/243 (29%), Positives = 104/243 (42%), Gaps = 19/243 (7%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHP--PSGAVE 149
NASLLI + D G+Y + + +G+GT + T+ KP + P A+E
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAME 163
Query: 150 YVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLV 209
V LTC+ E +Y W NG+ + + S N TL + VTK G Y C +
Sbjct: 164 TV---ILTCNPETPDA-SYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEI 219
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
N S SD + + +GP D V + GE + C A+S+PP YS
Sbjct: 220 WNSGSASRSDPVTLNLLHGP-------DLPRIFPSVTSYYSGENLDLSCFANSNPPAQYS 272
Query: 270 WIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTV-IITSVGLE 328
W T N + + G +L + + Y C A N+ TG + T T+ +I GL
Sbjct: 273 W---TINGKFQLS-GQKLFIPQITPKHNGL-YACSARNSATGEESSTSLTIRVIAPPGLG 327
Query: 329 KLA 331
A
Sbjct: 328 TFA 330
>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 2 precursor [Homo sapiens]
Length = 464
Score = 73.9 bits (180), Expect = 3e-13
Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 20/256 (7%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
PNASLLI + D G Y ++V A+ + V + P KP + + S VE
Sbjct: 103 PNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELP--KPSISSNN-SNPVED 159
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
+ TC E Y W N + + S S N TL + VT+ D G Y C ++
Sbjct: 160 KDAVAFTCEPETQDT-TYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQ 218
Query: 211 NPVSEMESDIIMPIIYYGPYGLQVN-SDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
NPVS SD + + YGP ++ SD + G ++ C A S+PP YS
Sbjct: 219 NPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSL--------SCYAASNPPAQYS 270
Query: 270 WIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEK 329
W+ N T+ + + + Y C A N++TG T T+I+T L
Sbjct: 271 WL---INGTF--QQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTE--LSP 323
Query: 330 LAQKGKSLSPLASITG 345
+ K + + ++TG
Sbjct: 324 VVAKPQIKASKTTVTG 339
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/170 (28%), Positives = 73/170 (42%), Gaps = 8/170 (4%)
Query: 87 TMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQK-IQVTVDDPVT-KPVVQIHPP 144
T L I + + G+Y N G + K I VT PV KP ++
Sbjct: 276 TFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKT 335
Query: 145 SGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGN 204
+ + ++ LTC T ++ +W + + +S S N TL I PV +ED G
Sbjct: 336 TVTGDK-DSVNLTCSTND-TGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGT 393
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPY----GLQVNSDKGLKVGEVFTVDL 250
Y C V NP+S+ +SD IM + Y GL + G+ +G V V L
Sbjct: 394 YWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVAL 443
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 73.9 bits (180), Expect = 3e-13
Identities = 72/256 (28%), Positives = 109/256 (42%), Gaps = 20/256 (7%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
PNASLLI + D G Y ++V A+ + V + P KP + + S VE
Sbjct: 103 PNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELP--KPSISSNN-SNPVED 159
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
+ TC E Y W N + + S S N TL + VT+ D G Y C ++
Sbjct: 160 KDAVAFTCEPETQDT-TYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQ 218
Query: 211 NPVSEMESDIIMPIIYYGPYGLQVN-SDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
NPVS SD + + YGP ++ SD + G ++ C A S+PP YS
Sbjct: 219 NPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSL--------SCYAASNPPAQYS 270
Query: 270 WIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEK 329
W+ N T+ + + + Y C A N++TG T T+I+T L
Sbjct: 271 WL---INGTF--QQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTE--LSP 323
Query: 330 LAQKGKSLSPLASITG 345
+ K + + ++TG
Sbjct: 324 VVAKPQIKASKTTVTG 339
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/170 (28%), Positives = 73/170 (42%), Gaps = 8/170 (4%)
Query: 87 TMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQK-IQVTVDDPVT-KPVVQIHPP 144
T L I + + G+Y N G + K I VT PV KP ++
Sbjct: 276 TFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKT 335
Query: 145 SGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGN 204
+ + ++ LTC T ++ +W + + +S S N TL I PV +ED G
Sbjct: 336 TVTGDK-DSVNLTCSTND-TGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGT 393
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPY----GLQVNSDKGLKVGEVFTVDL 250
Y C V NP+S+ +SD IM + Y GL + G+ +G V V L
Sbjct: 394 YWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVAL 443
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 68.2 bits (165), Expect = 1e-11
Identities = 77/304 (25%), Positives = 121/304 (39%), Gaps = 22/304 (7%)
Query: 21 KVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSV--NKSVVP 78
K+T+ S + G+ + L VH + P W + ++G V + P
Sbjct: 35 KLTIESTPFNVAEGKEVLLLVH---NLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATP 91
Query: 79 DLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPV 138
Y + ++ PNASLLI + D G Y + V A+ + +V + P KP
Sbjct: 92 GPAYSGR-EIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELP--KPS 148
Query: 139 VQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVT 198
+ + S VE + TC E Y W N + + S S N TL + VT
Sbjct: 149 ISSNN-SKPVEDKDAVAFTCEPETQDA-TYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVT 206
Query: 199 KEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDC 258
+ D +Y C +NPVS SD ++ + YGP ++ + GE + C
Sbjct: 207 RNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLN-------TSYRSGENLNLSC 259
Query: 259 SADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHF 318
A S+PP YSW N T+ + + + Y C A+N+ TG T
Sbjct: 260 HAASNPPAQYSWF---VNGTF--QQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVT 314
Query: 319 TVII 322
T+ +
Sbjct: 315 TITV 318
Score = 65.5 bits (158), Expect = 1e-10
Identities = 62/254 (24%), Positives = 99/254 (38%), Gaps = 16/254 (6%)
Query: 87 TMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSG 146
T L I + + G+Y + + G L+ + +TV KP + + S
Sbjct: 276 TFQQSTQELFIPNITVNNSGSYTCQAHNSDTG-LNRTTVTTITVYAEPPKPFITSNN-SN 333
Query: 147 AVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYS 206
VE + LTC E Y W N + + S S N TL + VT+ D+G Y
Sbjct: 334 PVEDEDAVALTCEPEI-QNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYE 392
Query: 207 CLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPN 266
C ++N +S SD ++ + YGP D + + G + C A S+PP
Sbjct: 393 CGIQNKLSVDHSDPVILNVLYGP------DDPTISPSYTY-YRPGVNLSLSCHAASNPPA 445
Query: 267 TYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVG 326
YSW+ + I +H L +++ + +K C NN T I S
Sbjct: 446 QYSWLIDGN----IQQHTQELFISN--ITEKNSGLYTCQANNSASGHSRTTVKTITVSAE 499
Query: 327 LEKLAQKGKSLSPL 340
L K + + P+
Sbjct: 500 LPKPSISSNNSKPV 513
Score = 56.6 bits (135), Expect = 4e-08
Identities = 57/255 (22%), Positives = 99/255 (38%), Gaps = 16/255 (6%)
Query: 95 LLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNM 154
L I+ + + G Y + N +G + K +TV + KP + + S VE +
Sbjct: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKT-ITVSAELPKPSISSNN-SKPVEDKDAV 519
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVS 214
TC E Y W NG+ + S S N TL + VT+ D Y C ++N VS
Sbjct: 520 AFTCEPEA-QNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVS 578
Query: 215 EMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRT 274
SD + + YGP ++ + G + C + S+P YSW
Sbjct: 579 ANRSDPVTLDVLYGPDTPIISPPDSSYLS-------GANLNLSCHSASNPSPQYSW---- 627
Query: 275 DNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEKLAQKG 334
I + ++ ++ Y C N TGR + ++ +++ G G
Sbjct: 628 -RINGIPQQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPGLSAG 686
Query: 335 KSLSPLASI-TGISL 348
++ + + G++L
Sbjct: 687 ATVGIMIGVLVGVAL 701
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 67.8 bits (164), Expect = 2e-11
Identities = 68/247 (27%), Positives = 106/247 (42%), Gaps = 24/247 (9%)
Query: 84 HKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHP 143
HKF + L I Q D G Y+ + N SA + + V P P V I P
Sbjct: 2919 HKF--LSNGRILQILNTQITDIGRYVC---VAENTAGSAKKYFNLNVHVP---PSV-IGP 2969
Query: 144 PSGAVEYVGN--MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKED 201
S + V N ++LTC V G WLKN +P+ ++ P TL I D
Sbjct: 2970 KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSD 3029
Query: 202 IGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSAD 261
G Y+C+ N E + + + Y P ++ + + L V V G ++ +C ++
Sbjct: 3030 GGEYTCIAINQAGESKKKFSLTV--YVPPSIKDHDSESL---SVVNVREGTSVSLECESN 3084
Query: 262 SHPPNTYSWIRR----TDNT-TYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDET 316
+ PP +W + T++T I+ G L + +V+ T YVC A N+ GR D+
Sbjct: 3085 AVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSD-TGQYVCRAI-NVAGRDDKN 3142
Query: 317 -HFTVII 322
H V +
Sbjct: 3143 FHLNVYV 3149
Score = 62.0 bits (149), Expect = 1e-09
Identities = 65/268 (24%), Positives = 108/268 (40%), Gaps = 31/268 (11%)
Query: 93 ASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
+ L I Q D GNY + N++G IQV V PS +
Sbjct: 3207 SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS------VAGAEIPSDVSVLL 3260
Query: 152 G-NMTLTCHVEGGTRLAYQWLKNGRPVHTSST--YSFSPQNNTLHIAPVTKEDIGNYSCL 208
G N+ L C+ G QWLK+G+P+ + T S +TL+I D G Y+C+
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 209 VRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
NP E D I + Y ++ N D+ K+ + + +I +C A PP
Sbjct: 3321 ATNPAG--EEDRIFNLNVYVTPTIRGNKDEAEKLMTL----VDTSINIECRATGTPPPQI 3374
Query: 269 SWIRR-----TDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII- 322
+W++ + ++ G + + +V+ + Y C A N D H+ + +
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAV-YTCVASNR--AGVDNKHYNLQVF 3431
Query: 323 ------TSVGLEKLAQKGKSLSPLASIT 344
S+G E++ S + +A IT
Sbjct: 3432 APPNMDNSMGTEEITVLKGSSTSMACIT 3459
Score = 60.8 bits (146), Expect = 2e-09
Identities = 54/217 (24%), Positives = 92/217 (42%), Gaps = 18/217 (8%)
Query: 95 LLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGN 153
L + + D G Y+ V VN+ G +K ++V P + P + +V +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAG----MTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
++LTC G + W K+G PV S++ L + T ED G Y+C+VRN
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR- 272
E E I + P+ + N+ + +KV E +++ C +P +W +
Sbjct: 2464 GE-ERKIFGLSVLVPPHIVGENTLEDVKVKE------KQSVTLTCEVTGNPVPEITWHKD 2516
Query: 273 ----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCA 305
+ D +II G L++ + +V T Y C A
Sbjct: 2517 GQPLQEDEAHHIISGGRFLQITNVQVPH-TGRYTCLA 2552
Score = 58.2 bits (139), Expect = 2e-08
Identities = 64/254 (25%), Positives = 98/254 (38%), Gaps = 21/254 (8%)
Query: 95 LLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNM 154
L I +Q P G Y + G S S + V V + +P V
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPA-GHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVS 214
+L C W K+G P+ ++ P TL I +++ G YSC+ N
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 215 EMESD-----IIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
EM I PII G GL EV + + + +C A + P + S
Sbjct: 2654 EMIKHYEVKVYIPPIINKGDLW-----GPGLSPKEV-KIKVNNTLTLECEAYAIPSASLS 2707
Query: 270 WIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTV-IIT 323
W + ++D+ I +G L++ +++ T Y C A +NI G +DE F V I
Sbjct: 2708 WYKDGQPLKSDDHVNIAANGHTLQIKEAQISD-TGRYTCVA-SNIAG-EDELDFDVNIQV 2764
Query: 324 SVGLEKLAQKGKSL 337
+KL + G L
Sbjct: 2765 PPSFQKLWEIGNML 2778
Score = 55.1 bits (131), Expect = 1e-07
Identities = 66/268 (24%), Positives = 102/268 (38%), Gaps = 28/268 (10%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
P+ L I+ D G Y+ + N +A KI++ V P PV+ H +
Sbjct: 4039 PSGGLQISRAVREDAGTYMC---VAQNPAGTALGKIKLNVQVP---PVISPHLKEYVIAV 4092
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
+TL+C +G W K+GR + S + +L IA V D G+Y+C+
Sbjct: 4093 DKPITLSCEADGLPPPDITWHKDGRAI-VESIRQRVLSSGSLQIAFVQPGDAGHYTCMAA 4151
Query: 211 NPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
N V+ S ++ P ++ S +G +TV+ + C AD P +W
Sbjct: 4152 N-VAGSSSTSTKLTVHVPP---RIRSTEG-----HYTVNENSQAILPCVADGIPTPAINW 4202
Query: 271 IRRTDNTTYIIKHG-----PRLEVASEKVAQKTMDYVCCAYNNITGRQDET-----HFTV 320
+ DN G P E+ E V + + C NN G T H
Sbjct: 4203 --KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Query: 321 IITSVGLEKLAQKGKSLSPLASITGISL 348
T + + KG+ L TGI L
Sbjct: 4261 TFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Score = 54.7 bits (130), Expect = 2e-07
Identities = 52/240 (21%), Positives = 94/240 (39%), Gaps = 15/240 (6%)
Query: 80 LEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVV 139
LE ++P +L I Q + G Y + G + +++V + + K +
Sbjct: 2616 LESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEA-GEMIKHYEVKVYIPPIINKGDL 2674
Query: 140 Q---IHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAP 196
+ P ++ +TL C + W K+G+P+ + + + +TL I
Sbjct: 2675 WGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKE 2734
Query: 197 VTKEDIGNYSCLVRNPVSEMESD----IIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGE 252
D G Y+C+ N E E D I +P + + + D G + GE V +
Sbjct: 2735 AQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTG-RNGEAKDVIINN 2793
Query: 253 AILFDCSADSHPPNTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
I C ++ PP T +W + + + I+ G L++ KV + Y C A N
Sbjct: 2794 PISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKV-EDAGRYTCVAVN 2852
Score = 54.3 bits (129), Expect = 2e-07
Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 23/235 (9%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQI 141
Q+ + + + SL I +Q D G Y V N+ G + S + V P + QI
Sbjct: 933 QNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL---PTIQHGQQI 989
Query: 142 HPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKED 201
+ +TL C G + + W K G + TSS + + +L++ E+
Sbjct: 990 LSTIEGIP----VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEE 1045
Query: 202 IGNYSCLVRNPVSEMESDI-----IMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILF 256
G Y C N + + + P ++ GL + DK +++ +V GE +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGL--SQDKPVEI----SVLAGEEVTL 1099
Query: 257 DCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQ-KTMD---YVCCAYN 307
C S PP +W + T + L S K+ + +T D Y+C A N
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Score = 53.5 bits (127), Expect = 4e-07
Identities = 55/224 (24%), Positives = 85/224 (37%), Gaps = 19/224 (8%)
Query: 91 PNASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVE 149
P+ S+ I + D G Y+ V NI GN T Q +++ V P P +Q P V+
Sbjct: 1131 PSGSMKITETRTSDSGMYLCVATNIAGNVT----QAVKLNVHVP---PKIQRGPKHLKVQ 1183
Query: 150 YVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLV 209
+ + C+ +G W K G + + S + TL I T D G Y+C+
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVA 1243
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
N E++I + + P + E + I F C A P T
Sbjct: 1244 TNIAGTDETEITLH-VQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIK 1299
Query: 270 WIRRTDNTT------YIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
W+ T I++ G L +AS +Y+C A N
Sbjct: 1300 WLHNGRELTGREPGISILEDGTLLVIAS-VTPYDNGEYICVAVN 1342
Score = 53.1 bits (126), Expect = 5e-07
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 14/164 (8%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+ LTC G W+K+GRP+ + L I+ ED G Y+CL +P
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR 273
+ + + ++ + + P + G TV + +C +D+ PP +W+R
Sbjct: 3606 GDDDKEYLVRV--HVPPNI-----AGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRN 3658
Query: 274 TDN-----TTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGR 312
+ I+ G L++ + + T +Y C A +NI G+
Sbjct: 3659 GERLQATPRVRILSGGRYLQINNADLGD-TANYTCVA-SNIAGK 3700
Score = 51.2 bits (121), Expect = 2e-06
Identities = 51/220 (23%), Positives = 82/220 (37%), Gaps = 20/220 (9%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
N SL + ++F D G Y V+ +G S++ + +TV +P P V + P + +
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGG---SSAASVFLTVQEP---PKVTVMPKNQSFTGG 626
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
+++ C G + W N + S Y + + TL I +D G Y CL N
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGTLFIKNAAPKDAGIYGCLASN 685
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW- 270
+ + + I + K + V V LG+ + +C PP W
Sbjct: 686 SAGTDKQNSTLRYI---------EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF 736
Query: 271 ---IRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+ +T II L E DY C A N
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAIN 776
Score = 51.2 bits (121), Expect = 2e-06
Identities = 57/231 (24%), Positives = 86/231 (37%), Gaps = 28/231 (12%)
Query: 126 IQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF 185
I+ + P+ K VV H ++TL C G WLK+G PV +
Sbjct: 1641 IEGNLATPLNKQVVIAH----------SLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 186 SPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEV 245
L I + D G Y C+ + E E I Y L + +G
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE-------IKYEVDVLVPPAIEGGDETSY 1743
Query: 246 FTVDLGEAILFDCSADSHPPNTYSWIRRTD-----NTTYIIKHGPRLEVASEKVAQKTMD 300
F V + + DC PP T W++ + I+ +G +L +A +V+ +
Sbjct: 1744 FIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGL- 1802
Query: 301 YVCCAYNNITGRQDETHFTV----IITSVGL-EKLAQKGKSLSPLASITGI 346
Y C A N + E TV I S GL E++ K K ++ GI
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGI 1853
Score = 50.8 bits (120), Expect = 2e-06
Identities = 59/255 (23%), Positives = 99/255 (38%), Gaps = 40/255 (15%)
Query: 64 MPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSAS 123
+PK L + N +++P F + ++ L+I + D G Y+ N
Sbjct: 4288 LPK-LTWTFNNNIIPA-----HFDSVNGHSELVIERVSKEDSGTYVCTAE---NSVGFVK 4338
Query: 124 QKIQVTVDDPVTKPVVQIHPPSGAVEYVG-NMTLTCHVEGGTRLAYQWLKNGRPVHTSST 182
V V +P PV + PS +E +G N L C V+G QW + G + S
Sbjct: 4339 AIGFVYVKEP---PVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR 4395
Query: 183 YSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIM-----PIIYYGPYGLQVNSD 237
N +L I ED G+Y+C+ N +E + + PII P +N+
Sbjct: 4396 IR-QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINA- 4453
Query: 238 KGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR-----TDNTTYIIKHGPRLEVASE 292
G I+ +C A P T +W R+ D+ ++ + ++
Sbjct: 4454 -------------GGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQ 4500
Query: 293 KVAQKTMDYVCCAYN 307
K + T ++ C A N
Sbjct: 4501 K--EDTSEFECVARN 4513
Score = 50.1 bits (118), Expect = 4e-06
Identities = 40/160 (25%), Positives = 61/160 (38%), Gaps = 10/160 (6%)
Query: 153 NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNP 212
++TLTC V G W K+G+P+ + L I V G Y+CL +P
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSP 2555
Query: 213 VSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
+ ++ P V SD E TV L C A S+PP T +W +
Sbjct: 2556 AGHKSRSFSLN-VFVSPTIAGVGSDGN---PEDVTVILNSPTSLVCEAYSYPPATITWFK 2611
Query: 273 -----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
++ I+ G L++ + + Y C A N
Sbjct: 2612 DGTPLESNRNIRILPGGRTLQILNAQ-EDNAGRYSCVATN 2650
Score = 49.7 bits (117), Expect = 5e-06
Identities = 38/182 (20%), Positives = 73/182 (40%), Gaps = 21/182 (11%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSE 215
L C G A W K+G+P+ +SS + + LHI D Y+C V N
Sbjct: 1567 LECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGT 1626
Query: 216 MES----DIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWI 271
E D+ +P + G +N V + ++ +C A +P +W+
Sbjct: 1627 AEKSFHVDVYVPPMIEGNLATPLNKQ----------VVIAHSLTLECKAAGNPSPILTWL 1676
Query: 272 R-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVG 326
+ + ++ I G +LE+ S + + Y+C A ++ G ++ + ++
Sbjct: 1677 KDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG-QYICVA-TSVAGEKEIKYEVDVLVPPA 1734
Query: 327 LE 328
+E
Sbjct: 1735 IE 1736
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/246 (21%), Positives = 96/246 (39%), Gaps = 29/246 (11%)
Query: 88 MMPPNASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSG 146
++P +L I + D G Y + +N G + +K +TV P P ++ H
Sbjct: 3013 IVPGGRTLQIIRAKVSDGGEYTCIAINQAGE----SKKKFSLTVYVP---PSIKDHDSES 3065
Query: 147 A----VEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDI 202
V +++L C W KNGR + S+ LHI D
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDT 3125
Query: 203 GNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADS 262
G Y C N + + + + Y P ++ EV + + C A
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNV--YVPPSIEGPER------EVIVETISNPVTLTCDATG 3177
Query: 263 HPPNTYSWI---RRTDNT----TYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDE 315
PP T +W+ +R +N+ I+ G +L++A + + + +Y C A +N+ G+ +
Sbjct: 3178 IPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSD-SGNYTCIA-SNMEGKAQK 3235
Query: 316 THFTVI 321
+F I
Sbjct: 3236 YYFLSI 3241
Score = 48.1 bits (113), Expect = 2e-05
Identities = 37/161 (22%), Positives = 67/161 (41%), Gaps = 14/161 (8%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSS-TYSFSPQNNTLHIAPVTKEDIGNYSCLVRNP 212
+ L C G + WLK+ +PV+T+ L IA ED G Y+C+ N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903
Query: 213 VSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
E + I + + + P L+ D G + E TV + + +C A +P +W +
Sbjct: 1904 AGETQQHIQLHV--HEPPSLE---DAGKMLNE--TVLVSNPVQLECKAAGNPVPVITWYK 1956
Query: 273 RT-----DNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNN 308
+ + G +++ S +++ + Y C A N+
Sbjct: 1957 DNRLLSGSTSMTFLNRGQIIDIESAQISDAGI-YKCVAINS 1996
Score = 47.8 bits (112), Expect = 2e-05
Identities = 59/243 (24%), Positives = 87/243 (35%), Gaps = 53/243 (21%)
Query: 94 SLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY-V 151
+L I Q D G Y V NI G L IQV PPS + +
Sbjct: 2729 TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQV--------------PPSFQKLWEI 2774
Query: 152 GNM------------------TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLH 193
GNM +L C W K+G P+ +S P L
Sbjct: 2775 GNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQ 2834
Query: 194 IAPVTKEDIGNYSCLVRNPVSE----MESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVD 249
I ED G Y+C+ N E + +++P I G NSD + E TV
Sbjct: 2835 IPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKG-----ANSD----LPEEVTVL 2885
Query: 250 LGEAILFDCSADSHPPNTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCC 304
+ ++ L +C + P SW + D+ + +G L++ + ++ YVC
Sbjct: 2886 VNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD-IGRYVCV 2944
Query: 305 AYN 307
A N
Sbjct: 2945 AEN 2947
Score = 46.2 bits (108), Expect = 6e-05
Identities = 57/232 (24%), Positives = 85/232 (36%), Gaps = 32/232 (13%)
Query: 104 DEGNYIVK-VNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSG-AVEYVGNMTLTCHVE 161
D G Y K +NI G SQK +D V ++ + P+ +V ++ L C V+
Sbjct: 1425 DAGRYSCKAINIAGT-----SQKY-FNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK 1478
Query: 162 GGTRLAYQWLKNGRPVHTSS-TYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDI 220
G W K+G+P+ + LH+ + D G Y C V N + DI
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 221 IMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW------IRRT 274
+ IY P S KG V +V + I +C P +W I +
Sbjct: 1539 KL-TIYIPP------SIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSS 1591
Query: 275 DNTTYIIK----HGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
YI K H PR +V+ + Y C N + H V +
Sbjct: 1592 SQALYIDKGQYLHIPRAQVSD------SATYTCHVANVAGTAEKSFHVDVYV 1637
Score = 46.2 bits (108), Expect = 6e-05
Identities = 39/154 (25%), Positives = 59/154 (38%), Gaps = 12/154 (7%)
Query: 117 NGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRP 176
N SA + + + V +P PV+Q P V + L C G W K G
Sbjct: 3971 NAAGSAHRHVTLHVHEP---PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGIN 4027
Query: 177 VHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNS 236
V+TS + L I+ +ED G Y C+ +NP I + +QV
Sbjct: 4028 VNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKL--------NVQVPP 4079
Query: 237 DKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
+ E + + + + I C AD PP +W
Sbjct: 4080 VISPHLKE-YVIAVDKPITLSCEADGLPPPDITW 4112
Score = 43.9 bits (102), Expect = 3e-04
Identities = 62/267 (23%), Positives = 100/267 (37%), Gaps = 30/267 (11%)
Query: 95 LLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGN 153
L + Q D G Y V VN G ++ V P + + +V
Sbjct: 2068 LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP-------PNIMGEEQNVSVLISQA 2120
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+ L C + WLK+G P+ S S + L I +D G Y+C N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR 273
+ E + + I G SD+ ++ TV G I C + PP W ++
Sbjct: 2181 GKTEKNYNVNIWVPPNIG---GSDELTQL----TVIEGNLISLLCESSGIPPPNLIWKKK 2233
Query: 274 -----TDN--TTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTV----II 322
TD+ I+ G +L+++ + + + Y C A N + E + V I
Sbjct: 2234 GSPVLTDSMGRVRILSGGRQLQISIAEKSDAAL-YSCVASNVAGTAKKEYNLQVYIRPTI 2292
Query: 323 TSVG---LEKLAQKGKSLSPLASITGI 346
T+ G E + +GKS+S + GI
Sbjct: 2293 TNSGSHPTEIIVTRGKSISLECEVQGI 2319
Score = 43.9 bits (102), Expect = 3e-04
Identities = 33/157 (21%), Positives = 64/157 (40%), Gaps = 15/157 (9%)
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVS 214
++ C +G + WL++G+P+ + + S L + ED G Y+C+ N
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 215 EMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR-- 272
E+ I+ + L+ G + E +V + + C A P +W++
Sbjct: 3514 EVSKHFILKV-------LEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDG 3566
Query: 273 ----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCA 305
+TD + G L +++ +V + T Y C A
Sbjct: 3567 RPLPQTDQ-VQTLGGGEVLRISTAQV-EDTGRYTCLA 3601
Score = 43.5 bits (101), Expect = 4e-04
Identities = 71/290 (24%), Positives = 113/290 (38%), Gaps = 63/290 (21%)
Query: 91 PNASLLINPL---------QFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQ 140
P+ L+I+PL Q D G+Y V +N G T KI + V P PV
Sbjct: 744 PSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT----GKITLDVGSP---PVFI 796
Query: 141 IHPPSGAVEYVGNMTLTCHVEGGTRLAYQW--LKN----GRPVHTSSTYSFSPQNNTLHI 194
P ++E N+TL C+V+G +W L N RP SS + L I
Sbjct: 797 QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQL--RTGALFI 854
Query: 195 APVTKEDIGNYSCLVRNPVSEMESD-------IIMPIIYYGPYGLQVNSDKGLKVGEVFT 247
+ D G Y C N +++S+ ++ P+I P V
Sbjct: 855 LNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISP--------------SVAN 900
Query: 248 VDLGEAILFDCS-ADSHPPNTYSWIRRTDNTTYIIKHGPRLEVAS------EKVAQKTMD 300
V G+ + C+ +P WI+ N+ ++++ P + V S E+V +
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIK---NSAMLLQN-PYITVRSDGSLHIERVQLQDGG 956
Query: 301 YVCCAYNNITGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFL 350
C +N+ G ++T TSV + L L++I GI + L
Sbjct: 957 EYTCVASNVAGTNNKT------TSVVVHVLPTIQHGQQILSTIEGIPVTL 1000
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 8/124 (6%)
Query: 104 DEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGG 163
D G YI V + GT ++V V PV K Q+ S + + N L C VEG
Sbjct: 1332 DNGEYIC-VAVNEAGTTERKYNLKVHVP-PVIKDKEQVTNVSVLLNQLTN--LFCEVEGT 1387
Query: 164 TRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMES----D 219
W K+ V SST L + T ED G YSC N + D
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNID 1447
Query: 220 IIMP 223
+++P
Sbjct: 1448 VLVP 1451
Score = 41.6 bits (96), Expect = 0.001
Identities = 38/164 (23%), Positives = 59/164 (35%), Gaps = 21/164 (12%)
Query: 153 NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNP 212
++ + C G WLKNG P+ SS + I D+ Y+C+ N
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 213 VSEMESDIIMPIIYYGPYGLQV----NSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
+ Y LQV N D + E+ TV G + C D P +
Sbjct: 3419 AG----------VDNKHYNLQVFAPPNMDNSMGTEEI-TVLKGSSTSMACITDGTPAPSM 3467
Query: 269 SWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+W+R D + HG L++ + + + Y C A N
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE-TEDSGKYTCIASN 3510
Score = 38.9 bits (89), Expect = 0.010
Identities = 43/201 (21%), Positives = 75/201 (37%), Gaps = 26/201 (12%)
Query: 118 GTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPV 177
GT +QV + +T HP V +++L C V+G W+K+G P+
Sbjct: 2276 GTAKKEYNLQVYIRPTITNS--GSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPL 2333
Query: 178 HTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVN-- 235
+ + + L + + D G Y C+ N + + + + P + N
Sbjct: 2334 IKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV--HAPPSIIGNHR 2391
Query: 236 SDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR-----RTDNTTYIIKHGPRLEVA 290
S + + V E +V L C A P + +W + N+ I+ G L
Sbjct: 2392 SPENISVVEKNSVSL------TCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRML--- 2442
Query: 291 SEKVAQKTMD----YVCCAYN 307
++ Q TM+ Y C N
Sbjct: 2443 --RLMQTTMEDAGQYTCVVRN 2461
Score = 38.5 bits (88), Expect = 0.013
Identities = 56/230 (24%), Positives = 83/230 (36%), Gaps = 29/230 (12%)
Query: 91 PNASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAV- 148
P+ +L I+ D G Y V NI G +I + V +P T V + PP
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTD----ETEITLHVQEPPT--VEDLEPPYNTTF 1275
Query: 149 -EYVGNMTLT--CHVEGGTRLAYQWLKNGRPV-HTSSTYSFSPQNNTLHIAPVTKEDIGN 204
E V N + C +G + +WL NGR + S L IA VT D G
Sbjct: 1276 QERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGE 1335
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFT---VDLGEAILFDCSAD 261
Y C+ N E Y L+V+ +K E T V L + C +
Sbjct: 1336 YICVAVNEAGTTER----------KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVE 1385
Query: 262 SHPPNTYSW----IRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
P W ++ T+++T + ++ + Y C A N
Sbjct: 1386 GTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAIN 1435
Score = 37.4 bits (85), Expect = 0.028
Identities = 44/209 (21%), Positives = 75/209 (35%), Gaps = 34/209 (16%)
Query: 135 TKPVVQIH---PPSGAVEYVGNMT-----------LTCHVEGGTRLAYQWLKNGRPVHTS 180
T+ +Q+H PPS +E G M L C G W K+ R + S
Sbjct: 1907 TQQHIQLHVHEPPS--LEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGS 1964
Query: 181 STYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGL 240
++ +F + + I D G Y C+ N E Y LQV+ +
Sbjct: 1965 TSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF----------YSLQVHVAPSI 2014
Query: 241 K-VGEVFTVDLGEAILFDCSADSHPPNTYSWIR------RTDNTTYIIKHGPRLEVASEK 293
+ V + + +C A P + +W++ N ++ G L + S +
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 294 VAQKTMDYVCCAYNNITGRQDETHFTVII 322
++ T Y C A N +Q + V +
Sbjct: 2075 ISD-TGRYTCVAVNAAGEKQRDIDLRVYV 2102
Score = 37.0 bits (84), Expect = 0.037
Identities = 35/160 (21%), Positives = 58/160 (36%), Gaps = 17/160 (10%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+TL C + WL+NG + + L I D NY+C+ N
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIA 3698
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVG-EVFTVDLGEAILFDCSADSHPPNTYSW-- 270
+ + I L VN +K G + + L ++ + +C A+ P +W
Sbjct: 3699 GKTTREFI----------LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRK 3748
Query: 271 ---IRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+ ++ Y I L + S V T Y+C A N
Sbjct: 3749 DGAVLAGNHARYSILENGFLHIQSAHVTD-TGRYLCMATN 3787
Score = 36.2 bits (82), Expect = 0.062
Identities = 39/180 (21%), Positives = 63/180 (35%), Gaps = 20/180 (11%)
Query: 151 VGNMT-LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLV 209
+G++T + C G +W K + S+ P L I D G+Y+C+
Sbjct: 715 LGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYS 269
N I + + P +Q +D +++G T+ C +P T
Sbjct: 775 INEAGRATGKITLD-VGSPPVFIQEPADVSMEIGSNVTL--------PCYVQGYPEPTIK 825
Query: 270 WIRRTDNTTYIIKHGPRLEVASEKV---------AQKTMDYVCCAYNNITGRQDETHFTV 320
W RR DN + ++ + A Y+C A N Q ET TV
Sbjct: 826 W-RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884
Score = 31.2 bits (69), Expect = 2.0
Identities = 29/123 (23%), Positives = 47/123 (38%), Gaps = 10/123 (8%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
N L I D G Y+ N + ++I + V P P + P + V
Sbjct: 3765 NGFLHIQSAHVTDTGRYLCMAT---NAAGTDRRRIDLQVHVP---PSIAPGPTNMTVIVN 3818
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVH---TSSTYSFSPQNNTLHIAPVTKEDIGNYSCL 208
TL C G + + W KNG ++ ++Y + + I+P + +D Y C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SVDDTATYECT 3877
Query: 209 VRN 211
V N
Sbjct: 3878 VTN 3880
>gi|54792136 follistatin-like 4 [Homo sapiens]
Length = 842
Score = 67.4 bits (163), Expect = 3e-11
Identities = 58/174 (33%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 104 DEGNYIVKVNI--QGNGTLSAS---QKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTC 158
D+ YI KV GN T AS Q Q V PV++++P S A E +L C
Sbjct: 303 DDSLYITKVTTIHMGNYTCHASGHEQLFQTHVLQVNVPPVIRVYPESQAQEPGVAASLRC 362
Query: 159 HVEGGTRLAYQWLKNGRPVHT--SSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEM 216
H EG WLKNG V T S S + LHI+ V ED G Y+C+ +N V +
Sbjct: 363 HAEGIPMPRITWLKNGVDVSTQMSKQLSLLANGSELHISSVRYEDTGAYTCIAKNEVG-V 421
Query: 217 ESDIIMPIIYYGPYGLQVN---SDKGLKVGEVFTVDLGEAIL----FDCSADSH 263
+ DI I N ++GL VG +F V + I+ DC H
Sbjct: 422 DEDISSLFIEDSARKTLANILWREEGLSVGNMFYVFSDDGIIVIHPVDCEIQRH 475
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 29/188 (15%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSP--QNNTLHIAPVTKEDIGNYSCLVRNPV 213
LTC V G R W +NG ++ + ++++L+I VT +GNY+C
Sbjct: 268 LTCAVHGDLRPPIIWKRNGLTLNFLDLEDINDFGEDDSLYITKVTTIHMGNYTCHASGHE 327
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKV-GEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
++ + LQVN ++V E + G A C A+ P +W++
Sbjct: 328 QLFQTHV-----------LQVNVPPVIRVYPESQAQEPGVAASLRCHAEGIPMPRITWLK 376
Query: 273 R-TDNTTYIIK------HGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSV 325
D +T + K +G L ++S + + T Y C A N + +D I+S+
Sbjct: 377 NGVDVSTQMSKQLSLLANGSELHISSVRY-EDTGAYTCIAKNEVGVDED-------ISSL 428
Query: 326 GLEKLAQK 333
+E A+K
Sbjct: 429 FIEDSARK 436
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 65.9 bits (159), Expect = 7e-11
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
Query: 134 VTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLH 193
+ KP + + P + A+E +T C + + W+ N V S L
Sbjct: 67 LAKPSIAVSPGT-AIEQKDMVTFYCTTKD-VNITIHWVSNNLSVVFHERMQLSKDGKILT 124
Query: 194 IAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEA 253
I V +ED G Y C R+ + SD I + YGP +++ + G+ GEV V G +
Sbjct: 125 ILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS 184
Query: 254 ILFDCSADSHPPNTYSW 270
+ F SHPP Y+W
Sbjct: 185 MTFLAETKSHPPCAYTW 201
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 120 LSASQKIQVTVDDPVTKPVVQIHPPS-GAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVH 178
LS+ ++V V + +T P Q+ P S VE ++ LTC + + QW +G+P+
Sbjct: 239 LSSLGTLKVRVLETLTMP--QVVPSSLNLVENARSVDLTCQTVNQS-VNVQWFLSGQPLL 295
Query: 179 TSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESD 219
S S N TL I + + D G Y+C V N S S+
Sbjct: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 65.9 bits (159), Expect = 7e-11
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
Query: 134 VTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLH 193
+ KP + + P + A+E +T C + + W+ N V S L
Sbjct: 67 LAKPSIAVSPGT-AIEQKDMVTFYCTTKD-VNITIHWVSNNLSVVFHERMQLSKDGKILT 124
Query: 194 IAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEA 253
I V +ED G Y C R+ + SD I + YGP +++ + G+ GEV V G +
Sbjct: 125 ILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS 184
Query: 254 ILFDCSADSHPPNTYSW 270
+ F SHPP Y+W
Sbjct: 185 MTFLAETKSHPPCAYTW 201
Score = 64.3 bits (155), Expect = 2e-10
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 10/208 (4%)
Query: 120 LSASQKIQVTVDDPVTKPVVQIHPPS-GAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVH 178
LS+ ++V V + +T P Q+ P S VE ++ LTC + + QW +G+P+
Sbjct: 239 LSSLGTLKVRVLETLTMP--QVVPSSLNLVENARSVDLTCQTVNQS-VNVQWFLSGQPLL 295
Query: 179 TSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDK 238
S S N TL I + + D G Y+C V N S S+ + I YGP + + +
Sbjct: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRES 355
Query: 239 GLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKT 298
++ +L ++ C A+S P Y W ++ G +L + +
Sbjct: 356 ASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHL---GEQLIIRALTWEHDG 412
Query: 299 MDYVCCAYNNITGRQDETHFTVIITSVG 326
+ Y C A N++TG T +V++ VG
Sbjct: 413 I-YNCTASNSLTGLARST--SVLVKVVG 437
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 65.9 bits (159), Expect = 7e-11
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
Query: 134 VTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLH 193
+ KP + + P + A+E +T C + + W+ N V S L
Sbjct: 67 LAKPSIAVSPGT-AIEQKDMVTFYCTTKD-VNITIHWVSNNLSVVFHERMQLSKDGKILT 124
Query: 194 IAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEA 253
I V +ED G Y C R+ + SD I + YGP +++ + G+ GEV V G +
Sbjct: 125 ILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS 184
Query: 254 ILFDCSADSHPPNTYSW 270
+ F SHPP Y+W
Sbjct: 185 MTFLAETKSHPPCAYTW 201
Score = 64.3 bits (155), Expect = 2e-10
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 10/208 (4%)
Query: 120 LSASQKIQVTVDDPVTKPVVQIHPPS-GAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVH 178
LS+ ++V V + +T P Q+ P S VE ++ LTC + + QW +G+P+
Sbjct: 239 LSSLGTLKVRVLETLTMP--QVVPSSLNLVENARSVDLTCQTVNQS-VNVQWFLSGQPLL 295
Query: 179 TSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDK 238
S S N TL I + + D G Y+C V N S S+ + I YGP + + +
Sbjct: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRES 355
Query: 239 GLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKT 298
++ +L ++ C A+S P Y W ++ G +L + +
Sbjct: 356 ASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHL---GEQLIIRALTWEHDG 412
Query: 299 MDYVCCAYNNITGRQDETHFTVIITSVG 326
+ Y C A N++TG T +V++ VG
Sbjct: 413 I-YNCTASNSLTGLARST--SVLVKVVG 437
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 65.9 bits (159), Expect = 7e-11
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
Query: 134 VTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLH 193
+ KP + + P + A+E +T C + + W+ N V S L
Sbjct: 67 LAKPSIAVSPGT-AIEQKDMVTFYCTTKD-VNITIHWVSNNLSVVFHERMQLSKDGKILT 124
Query: 194 IAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEA 253
I V +ED G Y C R+ + SD I + YGP +++ + G+ GEV V G +
Sbjct: 125 ILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS 184
Query: 254 ILFDCSADSHPPNTYSW 270
+ F SHPP Y+W
Sbjct: 185 MTFLAETKSHPPCAYTW 201
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 120 LSASQKIQVTVDDPVTKPVVQIHPPS-GAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVH 178
LS+ ++V V + +T P Q+ P S VE ++ LTC + + QW +G+P+
Sbjct: 239 LSSLGTLKVRVLETLTMP--QVVPSSLNLVENARSVDLTCQTVNQS-VNVQWFLSGQPLL 295
Query: 179 TSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESD 219
S S N TL I + + D G Y+C V N S S+
Sbjct: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 65.5 bits (158), Expect = 1e-10
Identities = 57/224 (25%), Positives = 91/224 (40%), Gaps = 28/224 (12%)
Query: 95 LLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQV--TVDDPVTKPVVQIHPPSGAVEYV 151
L I Q D+G Y KV N+ G + + +QV T ++P T+ V Q+ +G+
Sbjct: 1897 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQV---AGSP--- 1950
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
+ LTC V G WLK+ PV +S+ + + L ++ + G Y+C+ N
Sbjct: 1951 --LVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 2008
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWI 271
+E D ++ + L + V V G+ + DC AD PP +W+
Sbjct: 2009 TQAEARKDFVVAV-------LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWL 2061
Query: 272 RRTDNTTYIIKHGPRLE--------VASEKVAQKTMDYVCCAYN 307
+ D + GP L V A Y C A+N
Sbjct: 2062 K--DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHN 2103
Score = 58.9 bits (141), Expect = 9e-09
Identities = 51/183 (27%), Positives = 76/183 (41%), Gaps = 26/183 (14%)
Query: 95 LLINPLQFPDEGNY-IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPS--GAVEYV 151
L I Q D G+Y V N+ G+ L ++ V P + + PPS G V
Sbjct: 750 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVP-------PRITL-PPSLPGPVLVN 801
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFS--PQNNTLHIAPVTKEDIGNYSCLV 209
+ LTC+ G WLK+G PV + T P L +A D G YSC+
Sbjct: 802 TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVA 861
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDL--GEAILFDCSADSHPPNT 267
+ V E D++ LQV+ + +GE V + E++ +C + + PP
Sbjct: 862 VSAVGEDRQDVV----------LQVHMPPSI-LGEELNVSVVANESVALECQSHAMPPPV 910
Query: 268 YSW 270
SW
Sbjct: 911 LSW 913
Score = 55.8 bits (133), Expect = 8e-08
Identities = 53/215 (24%), Positives = 92/215 (42%), Gaps = 32/215 (14%)
Query: 114 IQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKN 173
I G SA +++ VTV++P++ + PS N+T W+K+
Sbjct: 1348 ILGGAEDSADEEVTVTVNNPISLICEALAFPSP------NIT--------------WMKD 1387
Query: 174 GRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQ 233
G P S P + L I KED G Y+C+V N + E + + ++ P +
Sbjct: 1388 GAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLI--PPSIS 1445
Query: 234 VNSDKG-LKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTT-----YIIKHGPRL 287
+ G + V EV T + + +C + + PP T W + T ++ G L
Sbjct: 1446 KDDPLGEVGVKEVKT-KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLL 1504
Query: 288 EVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
++ +V+ Y+C A N+ G +D+ F V+I
Sbjct: 1505 QIQPTQVSDSGR-YLCVA-TNVAG-EDDQDFNVLI 1536
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/219 (24%), Positives = 82/219 (37%), Gaps = 17/219 (7%)
Query: 95 LLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGN 153
L + Q EG Y + N+ GN +SQ +Q+ V P + P +V G
Sbjct: 1029 LYLGQAQLAQEGTYTCECSNVVGN----SSQDLQLEVHVPPQIAGPREPPTQVSVVQDGV 1084
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
TL C+ G W ++G+PV Q +LH+ G YSC+ N
Sbjct: 1085 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLA 1144
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR 273
E + ++ P L + D + T L + C A PP W R
Sbjct: 1145 GRAERKFELSVLV--PPELIGDLDPLTNI----TAALHSPLTLLCEAMGIPPPAIRWFRG 1198
Query: 274 TD-----NTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+ TY++ G L++ ++ Q + Y C A N
Sbjct: 1199 EEPVSPGEDTYLLAGGWMLKM-TQTQEQDSGLYSCLASN 1236
Score = 49.3 bits (116), Expect = 7e-06
Identities = 63/268 (23%), Positives = 99/268 (36%), Gaps = 27/268 (10%)
Query: 87 TMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSG 146
T + P L I D GNY+ I N SA K ++ V P PV++ P
Sbjct: 2803 TQVLPGGQLRIAHASPEDAGNYLC---IAKNSAGSAMGKTRLVVQVP---PVIENGLPDL 2856
Query: 147 AVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVH-TSSTYSFSPQNNTLHIAPVTKEDIGNY 205
+ + L C G W K+G+PV ++ P L + + +D G Y
Sbjct: 2857 STTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTY 2915
Query: 206 SCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPP 265
+C N V + + I+ P + D+ L+ LG+ + C+A P
Sbjct: 2916 TCTAENAVGRARRRVHLTILVL-PVFTTLPGDRSLR--------LGDRLWLRCAARGSPT 2966
Query: 266 NTYSWIRRTDNTTYIIKH---GPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
W T + G L+ A+ + + YVC A N + GR F +
Sbjct: 2967 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVS-REDSGTYVCWAENRV-GRTQAVSFVHV- 3023
Query: 323 TSVGLEKLAQKGKSLSPLASITGISLFL 350
E +G++ S L G S+ L
Sbjct: 3024 ----KEAPVLQGEAFSYLVEPVGGSIQL 3047
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/142 (26%), Positives = 57/142 (40%), Gaps = 21/142 (14%)
Query: 137 PVVQIHPPSGAVEYVG-NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIA 195
PV+Q S VE VG ++ L C V G W+K+G P+ S QN +L I
Sbjct: 3027 PVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR-GSHLRHQLQNGSLTIH 3085
Query: 196 PVTKEDIGNYSCLVRNPVSEMESDIIM-----PIIYYGPYGLQVNSDKGLKVGEVFTVDL 250
++D G Y CL N + + +I+ P+ P + V S
Sbjct: 3086 RTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRS-------------- 3131
Query: 251 GEAILFDCSADSHPPNTYSWIR 272
G+ + C A P T W++
Sbjct: 3132 GDDVALRCQATGEPTPTIEWLQ 3153
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 4/117 (3%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSE 215
L C+V G + W K+GRP+ + SP L + G+YSC+ N V E
Sbjct: 1274 LMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGE 1333
Query: 216 MESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
+ ++ P L D E TV + I C A + P +W++
Sbjct: 1334 KTKHFQLSVL-LAPTILGGAED---SADEEVTVTVNNPISLICEALAFPSPNITWMK 1386
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/190 (23%), Positives = 69/190 (36%), Gaps = 23/190 (12%)
Query: 86 FTMMPPNASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPP 144
+++ PP L I + DEG Y N+ G + K+ V P ++ P
Sbjct: 653 YSLPPP---LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVP-------PNIEPGPV 702
Query: 145 SGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGN 204
+ AV ++TL C G W K +PV + + S L I D G+
Sbjct: 703 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 762
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVF--TVDLGEAILFDCSADS 262
Y C+ N E YGL+VN + + V + + C+A
Sbjct: 763 YRCVASNVAGSTEL----------RYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATG 812
Query: 263 HPPNTYSWIR 272
P T W++
Sbjct: 813 APSPTLMWLK 822
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 21/165 (12%)
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
G + L C VE W ++G + + F + L + ++ D G+YSC RN
Sbjct: 2406 GQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 2465
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVG-EVFTVDLGEAILFDCSADSHPPNTYSW 270
+ +++++ ++ G V + + L C AD P SW
Sbjct: 2466 AAGSTSV----------AFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW 2515
Query: 271 IRRTDNTTYIIKHGPRLEVASE-------KVAQKTMDYVCCAYNN 308
R D + PR E+ E +AQ Y+C A N+
Sbjct: 2516 --RKDRVP-LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS 2557
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/250 (24%), Positives = 90/250 (36%), Gaps = 27/250 (10%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIH 142
Q + ++P NA LL P D + V+ N A + QVTV P P +
Sbjct: 2619 QGAYRLLPSNALLLTAPGP-QDSAQFECVVS---NEVGEAHRLYQVTVHVP---PTIADD 2671
Query: 143 PPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHT-SSTYSFSPQNNTLHIAPVTKED 201
V + + LTCH G W K G + S Y SP + L I
Sbjct: 2672 QTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP-SGALEIGQALPIH 2730
Query: 202 IGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLK-VGEVFTVDLGEAILFDCSA 260
G Y+C RN + L V + +K + V E +L C A
Sbjct: 2731 AGRYTCSARNSAGVAHKHVF----------LTVQASPVVKPLPSVVRAVAEEEVLLPCEA 2780
Query: 261 DSHPPNTYSWIRR-----TDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDE 315
P T +W + T +T ++ G +L +A + +Y+C A N+ +
Sbjct: 2781 SGIPRPTITWQKEGLNVATGVSTQVLP-GGQLRIAHAS-PEDAGNYLCIAKNSAGSAMGK 2838
Query: 316 THFTVIITSV 325
T V + V
Sbjct: 2839 TRLVVQVPPV 2848
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
N SL I+ + D G Y + ++K+ + V + PV Q+ P V
Sbjct: 3079 NGSLTIHRTERDDAGRY----QCLAENEMGVAKKVVILVLQ--SAPVFQVEPQDMTVRSG 3132
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
++ L C G +WL+ G+P+ S P + +L + V D G Y C+ N
Sbjct: 3133 DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP-DGSLWLENVETGDAGTYDCVAHN 3191
Score = 42.7 bits (99), Expect = 7e-04
Identities = 43/183 (23%), Positives = 67/183 (36%), Gaps = 19/183 (10%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
P SL I P+ D G+Y+ + N S Q + V +P P + P + +
Sbjct: 2533 PEGSLRIQPVLAQDAGHYLC---LASNSAGSDRQGRDLRVLEP---PAIAPSPSNLTLTA 2586
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVH---TSSTYSFSPQNNTLHIAPVTKEDIGNYSC 207
L C G + W K+G+ + Y P N L AP +D + C
Sbjct: 2587 HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAP-GPQDSAQFEC 2645
Query: 208 LVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNT 267
+V N V E + ++ P +D FTV + ++ C + P T
Sbjct: 2646 VVSNEVGEAHR-LYQVTVHVPPTIADDQTD--------FTVTMMAPVVLTCHSTGIPAPT 2696
Query: 268 YSW 270
SW
Sbjct: 2697 VSW 2699
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 8/90 (8%)
Query: 139 VQIHPPSGAVEYVGNMT--------LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN 190
VQ+ P E +G +T L C G QWL+NGRP + + Q
Sbjct: 493 VQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT 552
Query: 191 TLHIAPVTKEDIGNYSCLVRNPVSEMESDI 220
TLHI V + G ++C N +++
Sbjct: 553 TLHIDHVELDHSGLFACQATNEAGTAGAEV 582
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 14/140 (10%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+T+ C V G + WLK+G P+ S +TL I+ V D G ++C+ +P
Sbjct: 2140 VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPA 2199
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEV---FTVDLGEAILFDCSADSHPPNTYSW 270
+ + + LQV L+ E V G + C A P SW
Sbjct: 2200 GVADRN----------FTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSW 2249
Query: 271 IRRTDN-TTYIIKHGPRLEV 289
++ + + ++ GP L++
Sbjct: 2250 MKDGEPLLSQSLEQGPSLQL 2269
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 6/117 (5%)
Query: 95 LLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNM 154
L + L D G+Y G+ S + ++++ T P ++ PP+ V
Sbjct: 2446 LQLQALSTADSGDYSCTAR-NAAGSTSVAFRVEIH-----TVPTIRSGPPAVNVSVNQTA 2499
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
L C +G W K+ P+ S +L I PV +D G+Y CL N
Sbjct: 2500 LLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 2556
Score = 39.3 bits (90), Expect = 0.007
Identities = 29/119 (24%), Positives = 40/119 (33%), Gaps = 14/119 (11%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSE 215
L C G W K+G + TS+ ++ L + D G Y+C N V
Sbjct: 331 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA 390
Query: 216 MES----DIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
E D+ +P G G V G + +C A HP T SW
Sbjct: 391 AEKATRLDVYVPPTIEGAGGRPY----------VVKAVAGRPVALECVARGHPSPTLSW 439
Score = 38.9 bits (89), Expect = 0.010
Identities = 47/230 (20%), Positives = 78/230 (33%), Gaps = 26/230 (11%)
Query: 88 MMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGA 147
++P +L + + D G Y + L+A+ + Q V V P P G
Sbjct: 1795 LLPGTHTLQLGRARLSDSGMYTCEA-------LNAAGRDQKLVQLSVLVPPAFRQAPRGP 1847
Query: 148 VEYV-----GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDI 202
+ V L+C + W K+G+P+ + L I D
Sbjct: 1848 QDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDK 1907
Query: 203 GNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADS 262
G YSC V N E + + QV E + G ++ C
Sbjct: 1908 GLYSCKVSNVAGEAVRTFTLTV--------QVPPTFENPKTETVSQVAGSPLVLTCDVSG 1959
Query: 263 HPPNTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
P T +W++ + ++ G RL+++ + AQ Y C A N
Sbjct: 1960 VPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ-AGTYTCVAEN 2008
Score = 36.6 bits (83), Expect = 0.048
Identities = 54/276 (19%), Positives = 95/276 (34%), Gaps = 33/276 (11%)
Query: 65 PKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLI----NPLQFPDEGNYIVKVNIQGNGTL 120
P YL N PDL + + + + + LQ P +V+ G +
Sbjct: 1576 PAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIP-----LVRAENAGRYSC 1630
Query: 121 SASQKIQ---VTVDDPVTKPVVQIHPPSGAVEYV-----GNMTLTCHVEGGTRLAYQWLK 172
AS ++ + + V P V + VE V ++L C G WL+
Sbjct: 1631 KASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQ 1690
Query: 173 NGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGL 232
NG P S L ++ D +Y C+ N E + +
Sbjct: 1691 NGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV-------- 1742
Query: 233 QVNSD-KGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTD-----NTTYIIKHGPR 286
QV GL + +V T L ++ C +HP +W + + +++
Sbjct: 1743 QVPPRIAGLDLEQV-TAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT 1801
Query: 287 LEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
L++ +++ M Y C A N Q +V++
Sbjct: 1802 LQLGRARLSDSGM-YTCEALNAAGRDQKLVQLSVLV 1836
Score = 36.2 bits (82), Expect = 0.062
Identities = 53/227 (23%), Positives = 88/227 (38%), Gaps = 40/227 (17%)
Query: 94 SLLINPLQFPDEGNY-IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQI--HPPSGAVEY 150
SL + + D G Y V V+ G A + Q+TV +P P ++ P ++
Sbjct: 2266 SLQLEAVGAGDSGTYSCVAVSEAGE----ARRHFQLTVMEP---PHIEDSGQPTELSLTP 2318
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
M L C +G + W K+G+ + +NN+ + D G Y+CL
Sbjct: 2319 GAPMELLCDAQGTPQPNITWHKDGQALTRL-------ENNSRATRVLRVRDAGLYTCLAE 2371
Query: 211 NPVSEMESD----IIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEA-ILFDCSADSHPP 265
+P +E + P GP G + F V L ++ +CS ++ P
Sbjct: 2372 SPAGAIEKSFRVRVQAPPNIVGPRGPR------------FVVGLAPGQLVLECSVEAEPA 2419
Query: 266 NTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+W R + D T + G L++ + A + DY C A N
Sbjct: 2420 PKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTAD-SGDYSCTARN 2465
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/123 (22%), Positives = 44/123 (35%), Gaps = 15/123 (12%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+ L C G W G PV S+ + L + + G YSC+ +P
Sbjct: 423 VALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPA 482
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKV----GEVFTVDLGEAILFDCSADSHPPNTYS 269
E Y ++V L V G+V T+ +G+ + C A P T
Sbjct: 483 GEAVLQ----------YSVEVQVPPQLLVAEGLGQVTTI-VGQPLELPCQASGSPVPTIQ 531
Query: 270 WIR 272
W++
Sbjct: 532 WLQ 534
Score = 34.7 bits (78), Expect = 0.18
Identities = 30/124 (24%), Positives = 44/124 (35%), Gaps = 18/124 (14%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPV--HTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
L C +G WLK+G P+ F +L + + D G Y+C+ NP
Sbjct: 2046 LDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPA 2105
Query: 214 SE-----MESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
E + ++ P I G G G V GE + C PP
Sbjct: 2106 GEDARLHTVNVLVPPTIKQGADG------SGTLVSRP-----GELVTMVCPVRGSPPIHV 2154
Query: 269 SWIR 272
SW++
Sbjct: 2155 SWLK 2158
Score = 29.6 bits (65), Expect = 5.8
Identities = 22/88 (25%), Positives = 30/88 (34%), Gaps = 8/88 (9%)
Query: 138 VVQIHPPSGA------VEYVGN--MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN 189
V+Q+H P V V N + L C W K+GRP+ S
Sbjct: 873 VLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADK 932
Query: 190 NTLHIAPVTKEDIGNYSCLVRNPVSEME 217
L + D G+Y+C N E
Sbjct: 933 ALLQVDRADVWDAGHYTCEALNQAGRSE 960
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 65.5 bits (158), Expect = 1e-10
Identities = 57/224 (25%), Positives = 91/224 (40%), Gaps = 28/224 (12%)
Query: 95 LLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQV--TVDDPVTKPVVQIHPPSGAVEYV 151
L I Q D+G Y KV N+ G + + +QV T ++P T+ V Q+ +G+
Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQV---AGSP--- 3141
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
+ LTC V G WLK+ PV +S+ + + L ++ + G Y+C+ N
Sbjct: 3142 --LVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 3199
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWI 271
+E D ++ + L + V V G+ + DC AD PP +W+
Sbjct: 3200 TQAEARKDFVVAV-------LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWL 3252
Query: 272 RRTDNTTYIIKHGPRLE--------VASEKVAQKTMDYVCCAYN 307
+ D + GP L V A Y C A+N
Sbjct: 3253 K--DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHN 3294
Score = 58.9 bits (141), Expect = 9e-09
Identities = 51/183 (27%), Positives = 76/183 (41%), Gaps = 26/183 (14%)
Query: 95 LLINPLQFPDEGNY-IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPS--GAVEYV 151
L I Q D G+Y V N+ G+ L ++ V P + + PPS G V
Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVP-------PRITL-PPSLPGPVLVN 1992
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFS--PQNNTLHIAPVTKEDIGNYSCLV 209
+ LTC+ G WLK+G PV + T P L +A D G YSC+
Sbjct: 1993 TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVA 2052
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDL--GEAILFDCSADSHPPNT 267
+ V E D++ LQV+ + +GE V + E++ +C + + PP
Sbjct: 2053 VSAVGEDRQDVV----------LQVHMPPSI-LGEELNVSVVANESVALECQSHAMPPPV 2101
Query: 268 YSW 270
SW
Sbjct: 2102 LSW 2104
Score = 55.8 bits (133), Expect = 8e-08
Identities = 53/215 (24%), Positives = 92/215 (42%), Gaps = 32/215 (14%)
Query: 114 IQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKN 173
I G SA +++ VTV++P++ + PS N+T W+K+
Sbjct: 2539 ILGGAEDSADEEVTVTVNNPISLICEALAFPSP------NIT--------------WMKD 2578
Query: 174 GRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQ 233
G P S P + L I KED G Y+C+V N + E + + ++ P +
Sbjct: 2579 GAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLI--PPSIS 2636
Query: 234 VNSDKG-LKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTT-----YIIKHGPRL 287
+ G + V EV T + + +C + + PP T W + T ++ G L
Sbjct: 2637 KDDPLGEVGVKEVKT-KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLL 2695
Query: 288 EVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
++ +V+ Y+C A N+ G +D+ F V+I
Sbjct: 2696 QIQPTQVSDSGR-YLCVA-TNVAG-EDDQDFNVLI 2727
Score = 53.5 bits (127), Expect = 4e-07
Identities = 61/262 (23%), Positives = 98/262 (37%), Gaps = 27/262 (10%)
Query: 90 PPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVE 149
P + L + D+ Y+ + G + A ++ VT P P + P+ V
Sbjct: 842 PDSGVLFFESVAPEDQAPYVCEAR-NVFGKVQAEARLIVTGHAP---PQIASSAPTVRVL 897
Query: 150 YVGNMTLTCHVEGGTRLAYQ-WLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCL 208
++L C V G L + WLK+GRP+ S +S + +LH+ +E G YSC+
Sbjct: 898 EGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRA-DGSLHLDRALQEHAGRYSCV 956
Query: 209 VRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
N D+ ++ P + + + + G C A P T
Sbjct: 957 ATNTAGSQHRDV--ELVVQVPPRIHPTATHHI-------TNEGVPASLPCVASGVPAPTI 1007
Query: 269 SWIRRTDNTTYIIKHGPRLEVASEKV-------AQKTMDYVCCAYNNITGRQDETHFTVI 321
+W + T+ T GP V+ E AQ YVC A N + E +V
Sbjct: 1008 TWTKETNALT---SRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV- 1063
Query: 322 ITSVGLEKLAQKGKSLSPLASI 343
+ L K + L P S+
Sbjct: 1064 -NRLALSKYVWEEYGLLPSGSL 1084
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/219 (24%), Positives = 82/219 (37%), Gaps = 17/219 (7%)
Query: 95 LLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGN 153
L + Q EG Y + N+ GN +SQ +Q+ V P + P +V G
Sbjct: 2220 LYLGQAQLAQEGTYTCECSNVVGN----SSQDLQLEVHVPPQIAGPREPPTQVSVVQDGV 2275
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
TL C+ G W ++G+PV Q +LH+ G YSC+ N
Sbjct: 2276 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLA 2335
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR 273
E + ++ P L + D + T L + C A PP W R
Sbjct: 2336 GRAERKFELSVLV--PPELIGDLDPLTNI----TAALHSPLTLLCEAMGIPPPAIRWFRG 2389
Query: 274 TD-----NTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+ TY++ G L++ ++ Q + Y C A N
Sbjct: 2390 EEPVSPGEDTYLLAGGWMLKM-TQTQEQDSGLYSCLASN 2427
Score = 49.3 bits (116), Expect = 7e-06
Identities = 63/268 (23%), Positives = 99/268 (36%), Gaps = 27/268 (10%)
Query: 87 TMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSG 146
T + P L I D GNY+ I N SA K ++ V P PV++ P
Sbjct: 3994 TQVLPGGQLRIAHASPEDAGNYLC---IAKNSAGSAMGKTRLVVQVP---PVIENGLPDL 4047
Query: 147 AVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVH-TSSTYSFSPQNNTLHIAPVTKEDIGNY 205
+ + L C G W K+G+PV ++ P L + + +D G Y
Sbjct: 4048 STTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTY 4106
Query: 206 SCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPP 265
+C N V + + I+ P + D+ L+ LG+ + C+A P
Sbjct: 4107 TCTAENAVGRARRRVHLTILVL-PVFTTLPGDRSLR--------LGDRLWLRCAARGSPT 4157
Query: 266 NTYSWIRRTDNTTYIIKH---GPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
W T + G L+ A+ + + YVC A N + GR F +
Sbjct: 4158 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVS-REDSGTYVCWAENRV-GRTQAVSFVHV- 4214
Query: 323 TSVGLEKLAQKGKSLSPLASITGISLFL 350
E +G++ S L G S+ L
Sbjct: 4215 ----KEAPVLQGEAFSYLVEPVGGSIQL 4238
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/142 (26%), Positives = 57/142 (40%), Gaps = 21/142 (14%)
Query: 137 PVVQIHPPSGAVEYVG-NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIA 195
PV+Q S VE VG ++ L C V G W+K+G P+ S QN +L I
Sbjct: 4218 PVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR-GSHLRHQLQNGSLTIH 4276
Query: 196 PVTKEDIGNYSCLVRNPVSEMESDIIM-----PIIYYGPYGLQVNSDKGLKVGEVFTVDL 250
++D G Y CL N + + +I+ P+ P + V S
Sbjct: 4277 RTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRS-------------- 4322
Query: 251 GEAILFDCSADSHPPNTYSWIR 272
G+ + C A P T W++
Sbjct: 4323 GDDVALRCQATGEPTPTIEWLQ 4344
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 4/117 (3%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSE 215
L C+V G + W K+GRP+ + SP L + G+YSC+ N V E
Sbjct: 2465 LMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGE 2524
Query: 216 MESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
+ ++ P L D E TV + I C A + P +W++
Sbjct: 2525 KTKHFQLSVL-LAPTILGGAED---SADEEVTVTVNNPISLICEALAFPSPNITWMK 2577
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/190 (23%), Positives = 69/190 (36%), Gaps = 23/190 (12%)
Query: 86 FTMMPPNASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPP 144
+++ PP L I + DEG Y N+ G + K+ V P ++ P
Sbjct: 1844 YSLPPP---LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVP-------PNIEPGPV 1893
Query: 145 SGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGN 204
+ AV ++TL C G W K +PV + + S L I D G+
Sbjct: 1894 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 1953
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVF--TVDLGEAILFDCSADS 262
Y C+ N E YGL+VN + + V + + C+A
Sbjct: 1954 YRCVASNVAGSTEL----------RYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATG 2003
Query: 263 HPPNTYSWIR 272
P T W++
Sbjct: 2004 APSPTLMWLK 2013
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 21/165 (12%)
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
G + L C VE W ++G + + F + L + ++ D G+YSC RN
Sbjct: 3597 GQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 3656
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVG-EVFTVDLGEAILFDCSADSHPPNTYSW 270
+ +++++ ++ G V + + L C AD P SW
Sbjct: 3657 AAGSTSV----------AFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW 3706
Query: 271 IRRTDNTTYIIKHGPRLEVASE-------KVAQKTMDYVCCAYNN 308
R D + PR E+ E +AQ Y+C A N+
Sbjct: 3707 --RKDRVP-LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS 3748
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/250 (24%), Positives = 90/250 (36%), Gaps = 27/250 (10%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIH 142
Q + ++P NA LL P D + V+ N A + QVTV P P +
Sbjct: 3810 QGAYRLLPSNALLLTAPGP-QDSAQFECVVS---NEVGEAHRLYQVTVHVP---PTIADD 3862
Query: 143 PPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHT-SSTYSFSPQNNTLHIAPVTKED 201
V + + LTCH G W K G + S Y SP + L I
Sbjct: 3863 QTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP-SGALEIGQALPIH 3921
Query: 202 IGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLK-VGEVFTVDLGEAILFDCSA 260
G Y+C RN + L V + +K + V E +L C A
Sbjct: 3922 AGRYTCSARNSAGVAHKHVF----------LTVQASPVVKPLPSVVRAVAEEEVLLPCEA 3971
Query: 261 DSHPPNTYSWIRR-----TDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDE 315
P T +W + T +T ++ G +L +A + +Y+C A N+ +
Sbjct: 3972 SGIPRPTITWQKEGLNVATGVSTQVLP-GGQLRIAHAS-PEDAGNYLCIAKNSAGSAMGK 4029
Query: 316 THFTVIITSV 325
T V + V
Sbjct: 4030 TRLVVQVPPV 4039
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
N SL I+ + D G Y + ++K+ + V + PV Q+ P V
Sbjct: 4270 NGSLTIHRTERDDAGRY----QCLAENEMGVAKKVVILVLQ--SAPVFQVEPQDMTVRSG 4323
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
++ L C G +WL+ G+P+ S P + +L + V D G Y C+ N
Sbjct: 4324 DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP-DGSLWLENVETGDAGTYDCVAHN 4382
Score = 42.7 bits (99), Expect = 7e-04
Identities = 43/183 (23%), Positives = 67/183 (36%), Gaps = 19/183 (10%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
P SL I P+ D G+Y+ + N S Q + V +P P + P + +
Sbjct: 3724 PEGSLRIQPVLAQDAGHYLC---LASNSAGSDRQGRDLRVLEP---PAIAPSPSNLTLTA 3777
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVH---TSSTYSFSPQNNTLHIAPVTKEDIGNYSC 207
L C G + W K+G+ + Y P N L AP +D + C
Sbjct: 3778 HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAP-GPQDSAQFEC 3836
Query: 208 LVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNT 267
+V N V E + ++ P +D FTV + ++ C + P T
Sbjct: 3837 VVSNEVGEAHR-LYQVTVHVPPTIADDQTD--------FTVTMMAPVVLTCHSTGIPAPT 3887
Query: 268 YSW 270
SW
Sbjct: 3888 VSW 3890
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 8/90 (8%)
Query: 139 VQIHPPSGAVEYVGNMT--------LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN 190
VQ+ P E +G +T L C G QWL+NGRP + + Q
Sbjct: 1684 VQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT 1743
Query: 191 TLHIAPVTKEDIGNYSCLVRNPVSEMESDI 220
TLHI V + G ++C N +++
Sbjct: 1744 TLHIDHVELDHSGLFACQATNEAGTAGAEV 1773
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 14/140 (10%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+T+ C V G + WLK+G P+ S +TL I+ V D G ++C+ +P
Sbjct: 3331 VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPA 3390
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEV---FTVDLGEAILFDCSADSHPPNTYSW 270
+ + + LQV L+ E V G + C A P SW
Sbjct: 3391 GVADRN----------FTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSW 3440
Query: 271 IRRTDN-TTYIIKHGPRLEV 289
++ + + ++ GP L++
Sbjct: 3441 MKDGEPLLSQSLEQGPSLQL 3460
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 6/117 (5%)
Query: 95 LLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNM 154
L + L D G+Y G+ S + ++++ T P ++ PP+ V
Sbjct: 3637 LQLQALSTADSGDYSCTAR-NAAGSTSVAFRVEIH-----TVPTIRSGPPAVNVSVNQTA 3690
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
L C +G W K+ P+ S +L I PV +D G+Y CL N
Sbjct: 3691 LLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 3747
Score = 39.3 bits (90), Expect = 0.007
Identities = 29/119 (24%), Positives = 40/119 (33%), Gaps = 14/119 (11%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSE 215
L C G W K+G + TS+ ++ L + D G Y+C N V
Sbjct: 1522 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA 1581
Query: 216 MES----DIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
E D+ +P G G V G + +C A HP T SW
Sbjct: 1582 AEKATRLDVYVPPTIEGAGGRPY----------VVKAVAGRPVALECVARGHPSPTLSW 1630
Score = 38.9 bits (89), Expect = 0.010
Identities = 49/223 (21%), Positives = 79/223 (35%), Gaps = 33/223 (14%)
Query: 104 DEGNY-IVKVNIQGNGTLSASQKIQVTVDDP----VTKPVVQIHPPSGAVEYVGNMTLTC 158
+EG Y V+ G G A Q+ V DP V P V + P AV L+C
Sbjct: 490 EEGTYECTAVSRAGTGRAKA----QIVVTDPPPQLVPAPNVTVSPGETAV-------LSC 538
Query: 159 HVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMES 218
V G W+++ R + S+ + +L I+ + D G Y C+ N +
Sbjct: 539 RVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA 598
Query: 219 DIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRT---- 274
+ + + + +S G + CSA +P SW R +
Sbjct: 599 SVWLLVREAPQVSIHTSSQH---------FSQGVEVKVSCSASGYPTPHISWSRESQALQ 649
Query: 275 -DNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDET 316
D+ ++ G + + VA + C N G ET
Sbjct: 650 EDSRIHVDAQG---TLIIQGVAPEDAGNYSCQATNEVGTDQET 689
Score = 38.9 bits (89), Expect = 0.010
Identities = 47/230 (20%), Positives = 78/230 (33%), Gaps = 26/230 (11%)
Query: 88 MMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGA 147
++P +L + + D G Y + L+A+ + Q V V P P G
Sbjct: 2986 LLPGTHTLQLGRARLSDSGMYTCEA-------LNAAGRDQKLVQLSVLVPPAFRQAPRGP 3038
Query: 148 VEYV-----GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDI 202
+ V L+C + W K+G+P+ + L I D
Sbjct: 3039 QDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDK 3098
Query: 203 GNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADS 262
G YSC V N E + + QV E + G ++ C
Sbjct: 3099 GLYSCKVSNVAGEAVRTFTLTV--------QVPPTFENPKTETVSQVAGSPLVLTCDVSG 3150
Query: 263 HPPNTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
P T +W++ + ++ G RL+++ + AQ Y C A N
Sbjct: 3151 VPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ-AGTYTCVAEN 3199
Score = 38.5 bits (88), Expect = 0.013
Identities = 41/179 (22%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 94 SLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGN 153
+L+I + D GNY + N + + + + DP P V V
Sbjct: 661 TLIIQGVAPEDAGNYSCQAT---NEVGTDQETVTLYYTDP---PSVSAVNAVVLVAVGEE 714
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
L C G W + G + + S S + L I + D G Y+C N +
Sbjct: 715 AVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGK---LRIPAAQERDAGTYTCRAVNEL 771
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
+ ++I + + + P ++ D TV+LG + L C A PP T +W R
Sbjct: 772 GDASAEIQLAV-GHAPQLTELPRD--------VTVELGRSALLACRATGRPPPTVTWRR 821
Score = 36.6 bits (83), Expect = 0.048
Identities = 54/276 (19%), Positives = 95/276 (34%), Gaps = 33/276 (11%)
Query: 65 PKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLI----NPLQFPDEGNYIVKVNIQGNGTL 120
P YL N PDL + + + + + LQ P +V+ G +
Sbjct: 2767 PAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIP-----LVRAENAGRYSC 2821
Query: 121 SASQKIQ---VTVDDPVTKPVVQIHPPSGAVEYV-----GNMTLTCHVEGGTRLAYQWLK 172
AS ++ + + V P V + VE V ++L C G WL+
Sbjct: 2822 KASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQ 2881
Query: 173 NGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGL 232
NG P S L ++ D +Y C+ N E + +
Sbjct: 2882 NGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV-------- 2933
Query: 233 QVNSD-KGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTD-----NTTYIIKHGPR 286
QV GL + +V T L ++ C +HP +W + + +++
Sbjct: 2934 QVPPRIAGLDLEQV-TAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT 2992
Query: 287 LEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
L++ +++ M Y C A N Q +V++
Sbjct: 2993 LQLGRARLSDSGM-YTCEALNAAGRDQKLVQLSVLV 3027
Score = 36.2 bits (82), Expect = 0.062
Identities = 53/227 (23%), Positives = 88/227 (38%), Gaps = 40/227 (17%)
Query: 94 SLLINPLQFPDEGNY-IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQI--HPPSGAVEY 150
SL + + D G Y V V+ G A + Q+TV +P P ++ P ++
Sbjct: 3457 SLQLEAVGAGDSGTYSCVAVSEAGE----ARRHFQLTVMEP---PHIEDSGQPTELSLTP 3509
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
M L C +G + W K+G+ + +NN+ + D G Y+CL
Sbjct: 3510 GAPMELLCDAQGTPQPNITWHKDGQALTRL-------ENNSRATRVLRVRDAGLYTCLAE 3562
Query: 211 NPVSEMESD----IIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEA-ILFDCSADSHPP 265
+P +E + P GP G + F V L ++ +CS ++ P
Sbjct: 3563 SPAGAIEKSFRVRVQAPPNIVGPRGPR------------FVVGLAPGQLVLECSVEAEPA 3610
Query: 266 NTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+W R + D T + G L++ + A + DY C A N
Sbjct: 3611 PKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTAD-SGDYSCTARN 3656
Score = 35.4 bits (80), Expect = 0.11
Identities = 43/180 (23%), Positives = 64/180 (35%), Gaps = 19/180 (10%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
P+ SL + +Q D G+Y + N SAS + + V P P VQ P V
Sbjct: 1080 PSGSLRLAQVQVGDSGHYECTAS---NPAGSASHRYVLGVQVP---PQVQPGPRVLKVLV 1133
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
+ L C EG W K+G + PQ + +H A + D G Y C
Sbjct: 1134 GEALDLNCVAEGNPEPQLSWSKDGVVLQGRG-----PQGS-VHFAAIRTSDAGRYRCEAS 1187
Query: 211 NPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
N ++ + ++ +G S +V GE C A P +W
Sbjct: 1188 NSAGVDAWEVELRVLEPPHWGADETSGLLERVA-------GENASLPCPARGTPKPQVTW 1240
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/123 (22%), Positives = 44/123 (35%), Gaps = 15/123 (12%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+ L C G W G PV S+ + L + + G YSC+ +P
Sbjct: 1614 VALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPA 1673
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKV----GEVFTVDLGEAILFDCSADSHPPNTYS 269
E Y ++V L V G+V T+ +G+ + C A P T
Sbjct: 1674 GEAVLQ----------YSVEVQVPPQLLVAEGLGQVTTI-VGQPLELPCQASGSPVPTIQ 1722
Query: 270 WIR 272
W++
Sbjct: 1723 WLQ 1725
Score = 34.7 bits (78), Expect = 0.18
Identities = 30/124 (24%), Positives = 44/124 (35%), Gaps = 18/124 (14%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPV--HTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
L C +G WLK+G P+ F +L + + D G Y+C+ NP
Sbjct: 3237 LDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPA 3296
Query: 214 SE-----MESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
E + ++ P I G G G V GE + C PP
Sbjct: 3297 GEDARLHTVNVLVPPTIKQGADG------SGTLVSRP-----GELVTMVCPVRGSPPIHV 3345
Query: 269 SWIR 272
SW++
Sbjct: 3346 SWLK 3349
Score = 29.6 bits (65), Expect = 5.8
Identities = 22/88 (25%), Positives = 30/88 (34%), Gaps = 8/88 (9%)
Query: 138 VVQIHPPSGA------VEYVGN--MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN 189
V+Q+H P V V N + L C W K+GRP+ S
Sbjct: 2064 VLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADK 2123
Query: 190 NTLHIAPVTKEDIGNYSCLVRNPVSEME 217
L + D G+Y+C N E
Sbjct: 2124 ALLQVDRADVWDAGHYTCEALNQAGHSE 2151
Score = 29.3 bits (64), Expect = 7.6
Identities = 35/145 (24%), Positives = 56/145 (38%), Gaps = 14/145 (9%)
Query: 92 NASLLINPLQFPDEGNYIVK-VNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
+ L I Q D G Y + VN G+ AS +IQ+ V P + P VE
Sbjct: 747 SGKLRIPAAQERDAGTYTCRAVNELGD----ASAEIQLAVGHA---PQLTELPRDVTVEL 799
Query: 151 VGNMTLTCHVEGGTRLAYQWLK-NGRPVHTS-----STYSFSPQNNTLHIAPVTKEDIGN 204
+ L C G W + +G+P+ + S P + L V ED
Sbjct: 800 GRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAP 859
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGP 229
Y C RN +++++ + + + P
Sbjct: 860 YVCEARNVFGKVQAEARLIVTGHAP 884
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 65.5 bits (158), Expect = 1e-10
Identities = 57/224 (25%), Positives = 91/224 (40%), Gaps = 28/224 (12%)
Query: 95 LLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQV--TVDDPVTKPVVQIHPPSGAVEYV 151
L I Q D+G Y KV N+ G + + +QV T ++P T+ V Q+ +G+
Sbjct: 1806 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQV---AGSP--- 1859
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
+ LTC V G WLK+ PV +S+ + + L ++ + G Y+C+ N
Sbjct: 1860 --LVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 1917
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWI 271
+E D ++ + L + V V G+ + DC AD PP +W+
Sbjct: 1918 TQAEARKDFVVAV-------LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWL 1970
Query: 272 RRTDNTTYIIKHGPRLE--------VASEKVAQKTMDYVCCAYN 307
+ D + GP L V A Y C A+N
Sbjct: 1971 K--DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHN 2012
Score = 58.9 bits (141), Expect = 9e-09
Identities = 51/183 (27%), Positives = 76/183 (41%), Gaps = 26/183 (14%)
Query: 95 LLINPLQFPDEGNY-IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPS--GAVEYV 151
L I Q D G+Y V N+ G+ L ++ V P + + PPS G V
Sbjct: 659 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVP-------PRITL-PPSLPGPVLVN 710
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFS--PQNNTLHIAPVTKEDIGNYSCLV 209
+ LTC+ G WLK+G PV + T P L +A D G YSC+
Sbjct: 711 TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVA 770
Query: 210 RNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDL--GEAILFDCSADSHPPNT 267
+ V E D++ LQV+ + +GE V + E++ +C + + PP
Sbjct: 771 VSAVGEDRQDVV----------LQVHMPPSI-LGEELNVSVVANESVALECQSHAMPPPV 819
Query: 268 YSW 270
SW
Sbjct: 820 LSW 822
Score = 53.9 bits (128), Expect = 3e-07
Identities = 54/216 (25%), Positives = 92/216 (42%), Gaps = 34/216 (15%)
Query: 114 IQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKN 173
I G SA +++ VTV++P++ + PS N+T W+K+
Sbjct: 1257 ILGGAEDSADEEVTVTVNNPISLICEALAFPSP------NIT--------------WMKD 1296
Query: 174 GRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQ 233
G P S P + L I KED G Y+C+V N + E + + ++ P +
Sbjct: 1297 GAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLI--PPSIS 1354
Query: 234 VNSDKGLKVG--EVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTT-----YIIKHGPR 286
D +VG EV T + + +C + + PP T W + T ++ G
Sbjct: 1355 -KDDPLAEVGVKEVKT-KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL 1412
Query: 287 LEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
L++ +V+ Y+C A N+ G +D+ F V+I
Sbjct: 1413 LQIQPTQVSDSGR-YLCVA-TNVAG-EDDQDFNVLI 1445
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/219 (24%), Positives = 82/219 (37%), Gaps = 17/219 (7%)
Query: 95 LLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGN 153
L + Q EG Y + N+ GN +SQ +Q+ V P + P +V G
Sbjct: 938 LYLGQAQLAQEGTYTCECSNVVGN----SSQDLQLEVHVPPQIAGPREPPTQVSVVQDGV 993
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
TL C+ G W ++G+PV Q +LH+ G YSC+ N
Sbjct: 994 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLA 1053
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR 273
E + ++ P L + D + T L + C A PP W R
Sbjct: 1054 GRAERKFELSVLV--PPELIGDLDPLTNI----TAALHSPLTLLCEAMGIPPPAIRWFRG 1107
Query: 274 TD-----NTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+ TY++ G L++ ++ Q + Y C A N
Sbjct: 1108 EEPVSPGEDTYLLAGGWMLKM-TQTQEQDSGLYSCLASN 1145
Score = 49.3 bits (116), Expect = 7e-06
Identities = 63/268 (23%), Positives = 99/268 (36%), Gaps = 27/268 (10%)
Query: 87 TMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSG 146
T + P L I D GNY+ I N SA K ++ V P PV++ P
Sbjct: 2712 TQVLPGGQLRIAHASPEDAGNYLC---IAKNSAGSAMGKTRLVVQVP---PVIENGLPDL 2765
Query: 147 AVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVH-TSSTYSFSPQNNTLHIAPVTKEDIGNY 205
+ + L C G W K+G+PV ++ P L + + +D G Y
Sbjct: 2766 STTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTY 2824
Query: 206 SCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPP 265
+C N V + + I+ P + D+ L+ LG+ + C+A P
Sbjct: 2825 TCTAENAVGRARRRVHLTILVL-PVFTTLPGDRSLR--------LGDRLWLRCAARGSPT 2875
Query: 266 NTYSWIRRTDNTTYIIKH---GPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
W T + G L+ A+ + + YVC A N + GR F +
Sbjct: 2876 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVS-REDSGTYVCWAENRV-GRTQAVSFVHV- 2932
Query: 323 TSVGLEKLAQKGKSLSPLASITGISLFL 350
E +G++ S L G S+ L
Sbjct: 2933 ----KEAPVLQGEAFSYLVEPVGGSIQL 2956
Score = 48.5 bits (114), Expect = 1e-05
Identities = 38/142 (26%), Positives = 57/142 (40%), Gaps = 21/142 (14%)
Query: 137 PVVQIHPPSGAVEYVG-NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIA 195
PV+Q S VE VG ++ L C V G W+K+G P+ S QN +L I
Sbjct: 2936 PVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR-GSHLRHQLQNGSLTIR 2994
Query: 196 PVTKEDIGNYSCLVRNPVSEMESDIIM-----PIIYYGPYGLQVNSDKGLKVGEVFTVDL 250
++D G Y CL N + + +I+ P+ P + V S
Sbjct: 2995 RTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRS-------------- 3040
Query: 251 GEAILFDCSADSHPPNTYSWIR 272
G+ + C A P T W++
Sbjct: 3041 GDDVALRCQATGEPTPTIEWLQ 3062
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 4/117 (3%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSE 215
L C+V G + W K+GRP+ + SP L + G+YSC+ N V E
Sbjct: 1183 LMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGE 1242
Query: 216 MESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
+ ++ P L D E TV + I C A + P +W++
Sbjct: 1243 KTKHFQLSVL-LAPTILGGAED---SADEEVTVTVNNPISLICEALAFPSPNITWMK 1295
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/190 (23%), Positives = 69/190 (36%), Gaps = 23/190 (12%)
Query: 86 FTMMPPNASLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPP 144
+++ PP L I + DEG Y N+ G + K+ V P ++ P
Sbjct: 562 YSLPPP---LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVP-------PNIEPGPV 611
Query: 145 SGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGN 204
+ AV ++TL C G W K +PV + + S L I D G+
Sbjct: 612 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 671
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVF--TVDLGEAILFDCSADS 262
Y C+ N E YGL+VN + + V + + C+A
Sbjct: 672 YRCVASNVAGSTEL----------RYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATG 721
Query: 263 HPPNTYSWIR 272
P T W++
Sbjct: 722 APSPTLMWLK 731
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 21/165 (12%)
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
G + L C VE W ++G + + F + L + ++ D G+YSC RN
Sbjct: 2315 GQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARN 2374
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVG-EVFTVDLGEAILFDCSADSHPPNTYSW 270
+ +++++ ++ G V + + L C AD P SW
Sbjct: 2375 AAGSTSV----------AFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW 2424
Query: 271 IRRTDNTTYIIKHGPRLEVASE-------KVAQKTMDYVCCAYNN 308
R D + PR E+ E +AQ Y+C A N+
Sbjct: 2425 --RKDRVP-LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS 2466
Score = 44.3 bits (103), Expect = 2e-04
Identities = 60/250 (24%), Positives = 90/250 (36%), Gaps = 27/250 (10%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIH 142
Q + ++P NA LL P D + V+ N A + QVTV P P +
Sbjct: 2528 QGAYRLLPSNALLLTAPGP-QDSAQFECVVS---NEVGEAHRLYQVTVHVP---PTIADD 2580
Query: 143 PPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHT-SSTYSFSPQNNTLHIAPVTKED 201
V + + LTCH G W K G + S Y SP + L I
Sbjct: 2581 QTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP-SGALEIGQALPIH 2639
Query: 202 IGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLK-VGEVFTVDLGEAILFDCSA 260
G Y+C RN + L V + +K + V E +L C A
Sbjct: 2640 AGRYTCSARNSAGVAHKHVF----------LTVQASPVVKPLPSVVRAVAEEEVLLPCEA 2689
Query: 261 DSHPPNTYSWIRR-----TDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDE 315
P T +W + T +T ++ G +L +A + +Y+C A N+ +
Sbjct: 2690 SGIPRPTITWQKEGLNVATGVSTQVLP-GGQLRIAHAS-PEDAGNYLCIAKNSAGSAMGK 2747
Query: 316 THFTVIITSV 325
T V + V
Sbjct: 2748 TRLVVQVPPV 2757
Score = 42.7 bits (99), Expect = 7e-04
Identities = 43/183 (23%), Positives = 67/183 (36%), Gaps = 19/183 (10%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
P SL I P+ D G+Y+ + N S Q + V +P P + P + +
Sbjct: 2442 PEGSLRIQPVLAQDAGHYLC---LASNSAGSDRQGRDLRVLEP---PAIAPSPSNLTLTA 2495
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVH---TSSTYSFSPQNNTLHIAPVTKEDIGNYSC 207
L C G + W K+G+ + Y P N L AP +D + C
Sbjct: 2496 HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAP-GPQDSAQFEC 2554
Query: 208 LVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNT 267
+V N V E + ++ P +D FTV + ++ C + P T
Sbjct: 2555 VVSNEVGEAHR-LYQVTVHVPPTIADDQTD--------FTVTMMAPVVLTCHSTGIPAPT 2605
Query: 268 YSW 270
SW
Sbjct: 2606 VSW 2608
Score = 42.7 bits (99), Expect = 7e-04
Identities = 30/120 (25%), Positives = 48/120 (40%), Gaps = 7/120 (5%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
N SL I + D G Y + ++K+ + V + PV Q+ P V
Sbjct: 2988 NGSLTIRRTERDDAGRY----QCLAENEMGVAKKVVILVLQ--SAPVFQVEPQDMTVRSG 3041
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
++ L C G +WL+ G+P+ S P + +L + V D G Y C+ N
Sbjct: 3042 DDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP-DGSLWLENVETGDAGTYDCVAHN 3100
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 8/90 (8%)
Query: 139 VQIHPPSGAVEYVGNMT--------LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN 190
VQ+ P E +G +T L C G QWL+NGRP + + Q
Sbjct: 402 VQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT 461
Query: 191 TLHIAPVTKEDIGNYSCLVRNPVSEMESDI 220
TLHI V + G ++C N +++
Sbjct: 462 TLHIDHVELDHSGLFACQATNEAGTAGAEV 491
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 14/140 (10%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+T+ C V G + WLK+G P+ S +TL I+ V D G ++C+ +P
Sbjct: 2049 VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPA 2108
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEV---FTVDLGEAILFDCSADSHPPNTYSW 270
+ + + LQV L+ E V G + C A P SW
Sbjct: 2109 GVADRN----------FTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSW 2158
Query: 271 IRRTDN-TTYIIKHGPRLEV 289
++ + + ++ GP L++
Sbjct: 2159 MKDGEPLLSQSLEQGPSLQL 2178
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 6/117 (5%)
Query: 95 LLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNM 154
L + L D G+Y G+ S + ++++ T P ++ PP+ V
Sbjct: 2355 LQLQALSTADSGDYSCTAR-NAAGSTSVAFRVEIH-----TVPTIRSGPPAVNVSVNQTA 2408
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
L C +G W K+ P+ S +L I PV +D G+Y CL N
Sbjct: 2409 LLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 2465
Score = 39.3 bits (90), Expect = 0.007
Identities = 29/119 (24%), Positives = 40/119 (33%), Gaps = 14/119 (11%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSE 215
L C G W K+G + TS+ ++ L + D G Y+C N V
Sbjct: 240 LLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGA 299
Query: 216 MES----DIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
E D+ +P G G V G + +C A HP T SW
Sbjct: 300 AEKATRLDVYVPPTIEGAGGRPY----------VVKAVAGRPVALECVARGHPSPTLSW 348
Score = 38.9 bits (89), Expect = 0.010
Identities = 47/230 (20%), Positives = 78/230 (33%), Gaps = 26/230 (11%)
Query: 88 MMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGA 147
++P +L + + D G Y + L+A+ + Q V V P P G
Sbjct: 1704 LLPGTHTLQLGRARLSDSGMYTCEA-------LNAAGRDQKLVQLSVLVPPAFRQAPRGP 1756
Query: 148 VEYV-----GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDI 202
+ V L+C + W K+G+P+ + L I D
Sbjct: 1757 QDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDK 1816
Query: 203 GNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADS 262
G YSC V N E + + QV E + G ++ C
Sbjct: 1817 GLYSCKVSNVAGEAVRTFTLTV--------QVPPTFENPKTETVSQVAGSPLVLTCDVSG 1868
Query: 263 HPPNTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
P T +W++ + ++ G RL+++ + AQ Y C A N
Sbjct: 1869 VPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ-AGTYTCVAEN 1917
Score = 36.6 bits (83), Expect = 0.048
Identities = 54/276 (19%), Positives = 95/276 (34%), Gaps = 33/276 (11%)
Query: 65 PKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLI----NPLQFPDEGNYIVKVNIQGNGTL 120
P YL N PDL + + + + + LQ P +V+ G +
Sbjct: 1485 PAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIP-----LVRAENAGRYSC 1539
Query: 121 SASQKIQ---VTVDDPVTKPVVQIHPPSGAVEYV-----GNMTLTCHVEGGTRLAYQWLK 172
AS ++ + + V P V + VE V ++L C G WL+
Sbjct: 1540 KASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQ 1599
Query: 173 NGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGL 232
NG P S L ++ D +Y C+ N E + +
Sbjct: 1600 NGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV-------- 1651
Query: 233 QVNSD-KGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTD-----NTTYIIKHGPR 286
QV GL + +V T L ++ C +HP +W + + +++
Sbjct: 1652 QVPPRIAGLDLEQV-TAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT 1710
Query: 287 LEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVII 322
L++ +++ M Y C A N Q +V++
Sbjct: 1711 LQLGRARLSDSGM-YTCEALNAAGRDQKLVQLSVLV 1745
Score = 36.2 bits (82), Expect = 0.062
Identities = 53/227 (23%), Positives = 88/227 (38%), Gaps = 40/227 (17%)
Query: 94 SLLINPLQFPDEGNY-IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQI--HPPSGAVEY 150
SL + + D G Y V V+ G A + Q+TV +P P ++ P ++
Sbjct: 2175 SLQLEAVGAGDSGTYSCVAVSEAGE----ARRHFQLTVMEP---PHIEDSGQPTELSLTP 2227
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
M L C +G + W K+G+ + +NN+ + D G Y+CL
Sbjct: 2228 GAPMELLCDAQGTPQPNITWHKDGQALTRL-------ENNSRATRVLRVRDAGLYTCLAE 2280
Query: 211 NPVSEMESD----IIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEA-ILFDCSADSHPP 265
+P +E + P GP G + F V L ++ +CS ++ P
Sbjct: 2281 SPAGAIEKSFRVRVQAPPNIVGPRGPR------------FVVGLAPGQLVLECSVEAEPA 2328
Query: 266 NTYSWIR-----RTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYN 307
+W R + D T + G L++ + A + DY C A N
Sbjct: 2329 PKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTAD-SGDYSCTARN 2374
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/123 (22%), Positives = 44/123 (35%), Gaps = 15/123 (12%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+ L C G W G PV S+ + L + + G YSC+ +P
Sbjct: 332 VALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPA 391
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKV----GEVFTVDLGEAILFDCSADSHPPNTYS 269
E Y ++V L V G+V T+ +G+ + C A P T
Sbjct: 392 GEAVLQ----------YSVEVQVPPQLLVAEGLGQVTTI-VGQPLELPCQASGSPVPTIQ 440
Query: 270 WIR 272
W++
Sbjct: 441 WLQ 443
Score = 34.7 bits (78), Expect = 0.18
Identities = 30/124 (24%), Positives = 44/124 (35%), Gaps = 18/124 (14%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPV--HTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
L C +G WLK+G P+ F +L + + D G Y+C+ NP
Sbjct: 1955 LDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPA 2014
Query: 214 SE-----MESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
E + ++ P I G G G V GE + C PP
Sbjct: 2015 GEDARLHTVNVLVPPTIKQGADG------SGTLVSRP-----GELVTMVCPVRGSPPIHV 2063
Query: 269 SWIR 272
SW++
Sbjct: 2064 SWLK 2067
Score = 29.6 bits (65), Expect = 5.8
Identities = 22/88 (25%), Positives = 30/88 (34%), Gaps = 8/88 (9%)
Query: 138 VVQIHPPSGA------VEYVGN--MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN 189
V+Q+H P V V N + L C W K+GRP+ S
Sbjct: 782 VLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADK 841
Query: 190 NTLHIAPVTKEDIGNYSCLVRNPVSEME 217
L + D G+Y+C N E
Sbjct: 842 ALLQVDRADVWDAGHYTCEALNQAGHSE 869
>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/233 (24%), Positives = 96/233 (41%), Gaps = 14/233 (6%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
NASLLI + D G+Y + + +G+ T + + + KP + I+ S E
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINN-SKPRENK 162
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
+ TC + Y W NG+ + S +N L + VT+ + G Y C +R+
Sbjct: 163 DVLAFTCEPKS-ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWI 271
M SD + + YGP D GE + C A+S+PP Y W
Sbjct: 222 RDGGMRSDPVTLNVLYGP-------DLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFW- 273
Query: 272 RRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITS 324
T N + + G +L + + + Y C N+ TG++ TV +++
Sbjct: 274 --TINGKF-QQSGQKLSIPQITTKHRGL-YTCSVRNSATGKESSKSMTVEVSA 322
Score = 38.9 bits (89), Expect = 0.010
Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 15/107 (14%)
Query: 132 DPVTKPVV------QIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF 185
DPVT V+ I+P N+ L+C E Y W NG+ F
Sbjct: 229 DPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGK---------F 279
Query: 186 SPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGL 232
L I +T + G Y+C VRN + ES M + P G+
Sbjct: 280 QQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAPSGI 326
>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/233 (24%), Positives = 96/233 (41%), Gaps = 14/233 (6%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYV 151
NASLLI + D G+Y + + +G+ T + + + KP + I+ S E
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINN-SKPRENK 162
Query: 152 GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
+ TC + Y W NG+ + S +N L + VT+ + G Y C +R+
Sbjct: 163 DVLAFTCEPKS-ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221
Query: 212 PVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWI 271
M SD + + YGP D GE + C A+S+PP Y W
Sbjct: 222 RDGGMRSDPVTLNVLYGP-------DLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFW- 273
Query: 272 RRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITS 324
T N + + G +L + + + Y C N+ TG++ TV +++
Sbjct: 274 --TINGKF-QQSGQKLSIPQITTKHRGL-YTCSVRNSATGKESSKSMTVEVSA 322
Score = 38.9 bits (89), Expect = 0.010
Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 15/107 (14%)
Query: 132 DPVTKPVV------QIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF 185
DPVT V+ I+P N+ L+C E Y W NG+ F
Sbjct: 229 DPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGK---------F 279
Query: 186 SPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGL 232
L I +T + G Y+C VRN + ES M + P G+
Sbjct: 280 QQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAPSGI 326
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 63.5 bits (153), Expect = 4e-10
Identities = 59/246 (23%), Positives = 94/246 (38%), Gaps = 24/246 (9%)
Query: 121 SASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTS 180
+AS ++T +P P I P S V + CHV G + W K+ + +
Sbjct: 6255 TASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPG 6314
Query: 181 STYSFSPQNNTLH--IAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDK 238
Y+ + NT H I V K D G Y+C N V + + + + ++ + K
Sbjct: 6315 GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASK 6374
Query: 239 GLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTD--------NTTYIIKHGPRLEVA 290
K GE+I +C P SW R N ++I + L
Sbjct: 6375 VAK--------QGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFI--NSVALLTI 6424
Query: 291 SEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEKL----AQKGKSLSPLASITGI 346
+E A+ + DY+C A+N + T TV V +K A KG + I+G
Sbjct: 6425 NEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGT 6484
Query: 347 SLFLII 352
F ++
Sbjct: 6485 PPFEVV 6490
Score = 55.8 bits (133), Expect = 8e-08
Identities = 36/110 (32%), Positives = 48/110 (43%), Gaps = 5/110 (4%)
Query: 104 DEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGG 163
D G Y KV+ L S + + +P PV H V + L+CHV+G
Sbjct: 8316 DAGLYTCKVSNDAGSALCTSS---IVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGS 8372
Query: 164 TRLAYQWLKNGRPVHTSSTYSFSPQNNT--LHIAPVTKEDIGNYSCLVRN 211
+ QWLK GR + S SFS + T L + V K D G+Y C N
Sbjct: 8373 EPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASN 8422
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/289 (22%), Positives = 111/289 (38%), Gaps = 41/289 (14%)
Query: 51 DIQIIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIV 110
+I+++W F H +P +++ T + A + +N L D G++I
Sbjct: 5452 EIRVVW-FRNEHELPA--------------SDKYRMTFIDSVAVIQMNNLSTEDSGDFIC 5496
Query: 111 KVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQW 170
+ N S S +V V +P PV PP ++L C + G W
Sbjct: 5497 EAQ---NPAGSTSCSTKVIVKEP---PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVW 5550
Query: 171 LKNGRPVHTSSTYSFSPQN--NTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYG 228
K+ R + +S Y + +N ++HI V DIG Y C +N V + +
Sbjct: 5551 YKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 5610
Query: 229 PYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW-------IRRTDNTTY-I 280
+ ++NS TV GE S + P W IR ++N
Sbjct: 5611 RFVSKLNS---------LTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITF 5661
Query: 281 IKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEK 329
+++ L+ A + A Y+C N+ R++ V+ +V +EK
Sbjct: 5662 VENVATLQFAKAEPA-NAGKYICQIKNDGGMRENMATLMVLEPAVIVEK 5709
Score = 51.2 bits (121), Expect = 2e-06
Identities = 62/259 (23%), Positives = 110/259 (42%), Gaps = 28/259 (10%)
Query: 82 YQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQI 141
+++ + + A L IN D G+YI + + NG AS +TV P PV
Sbjct: 6409 WKYNMSFINSVALLTINEASAEDSGDYICEAH---NGVGDASCSTALTVKAP---PVFTQ 6462
Query: 142 HP-PSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN--NTLHIAPVT 198
P P GA++ ++ L C + G W+K+ + V S + + ++ +LHI +
Sbjct: 6463 KPSPVGALKG-SDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLE 6521
Query: 199 KEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDC 258
D+G Y C N E+ SD + + V K+ + T+ +G+A+
Sbjct: 6522 ASDVGEYHCKATN---EVGSDTCSCSVKFKEPPRFVK-----KLSDTSTL-IGDAVELRA 6572
Query: 259 SADSHPPNTYSW-------IRRTDNTTY-IIKHGPRLEVASEKVAQKTMDYVCCAYNNIT 310
+ P + W IR ++NT I + L++ S + A + Y+C N+
Sbjct: 6573 IVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPE-ASNSGKYICQIKNDAG 6631
Query: 311 GRQDETHFTVIITSVGLEK 329
R+ TV+ + +EK
Sbjct: 6632 MRECSAVLTVLEPARIIEK 6650
Score = 50.4 bits (119), Expect = 3e-06
Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 8/131 (6%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIH 142
+H + + A+ I+ + + G Y+ + N +AS I++ V +P T ++
Sbjct: 4907 KHGISFIDGLATFQISGARVENSGTYVCEAR---NDAGTASCSIELKVKEPPT--FIREL 4961
Query: 143 PPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHIAPVTKE 200
P V+Y ++ L C V G WLKN R + +S Y+ + + + LHI
Sbjct: 4962 KPVEVVKY-SDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPS 5020
Query: 201 DIGNYSCLVRN 211
D G Y C+V N
Sbjct: 5021 DTGEYQCIVSN 5031
Score = 50.1 bits (118), Expect = 4e-06
Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 36/203 (17%)
Query: 134 VTKPVVQIHPPSGAVEYVGNM-TLTCHVEGGTRLAYQWLKNGRPVHTSSTY--SFSPQNN 190
V +P + P G+ TL C V G L+ +W K+G+ + + + Y SF + +
Sbjct: 7582 VLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS 7641
Query: 191 TLHIAPVTKEDIGNYSCLVRNPV-------SEMESDIIMPIIYYGPYGLQVNSDKGLKVG 243
L I V D G YS V+NPV S SD +P + ++ GL
Sbjct: 7642 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVP----PSFTRKLKETNGLS-- 7695
Query: 244 EVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTM-DYV 302
G +++ +C PP + SW + E++S + Q T+ D
Sbjct: 7696 -------GSSVVMECKVYGSPPISVSWFHEGN------------EISSGRKYQTTLTDNT 7736
Query: 303 CCAYNNITGRQDETHFTVIITSV 325
C N+ D +T I T++
Sbjct: 7737 CALTVNMLEESDSGDYTCIATNM 7759
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 29/193 (15%)
Query: 144 PSGAVEYVGNMTLT--------CHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN--NTLH 193
P+ VE G MT+T C V G L+ +W K+G+ + +S + FS N ++L
Sbjct: 5703 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLR 5762
Query: 194 IAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLK-VGEVFTVDLGE 252
I V ++D G Y+ V+N V + ++ + + + + LK G V LG
Sbjct: 5763 ILSVERQDAGTYTFQVQNNVGKSSCTAVVDV---SDRAVPPSFTRRLKNTGGV----LGA 5815
Query: 253 AILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGR 312
+ + +C P + +W H V+ K D VC N
Sbjct: 5816 SCILECKVAGSSPISVAWF-----------HEKTKIVSGAKYQTTFSDNVCTLQLNSLDS 5864
Query: 313 QDETHFTVIITSV 325
D ++T + +V
Sbjct: 5865 SDMGNYTCVAANV 5877
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/293 (21%), Positives = 107/293 (36%), Gaps = 33/293 (11%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIH 142
+HKF+ +SL I ++ D G Y +V N +S V V D P
Sbjct: 5749 KHKFSFYNKISSLRILSVERQDAGTYTFQVQ---NNVGKSSCTAVVDVSDRAVPPSFTRR 5805
Query: 143 PPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTY--SFSPQNNTLHIAPVTKE 200
+ + L C V G + ++ W + + + Y +FS TL + +
Sbjct: 5806 LKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSS 5865
Query: 201 DIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSA 260
D+GNY+C+ N E ++ + +K E V G+ + F
Sbjct: 5866 DMGNYTCVAANVAGSDECRAVLTV---------QEPPSFVKEPEPLEVLPGKNVTFTSVI 5916
Query: 261 DSHPPNTYSWIRRTDN-------TTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQ 313
PP +W R Y LE+ + ++Q + +Y C NN
Sbjct: 5917 RGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQ-SGEYTCVVSNNAGQAS 5975
Query: 314 DETHFTVIITSVGLEKLA----QKGKSLSPLASITGISLFLIISMCLLFLWKK 362
T V + L++L+ + GKS+ ++ TG ++ + WKK
Sbjct: 5976 CTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTG-------TLPISVTWKK 6021
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/122 (28%), Positives = 51/122 (41%), Gaps = 10/122 (8%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHIAPVTKEDIGNYSCLVRN 211
MTL C V G L +WLK+G+ + S +S S +NN + I V K+D G Y+ V N
Sbjct: 5158 MTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVEN 5217
Query: 212 PVSEMESDIIMPIIYYG-PYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
D + ++ P K KV LG +I +C P + W
Sbjct: 5218 DFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKV-------LGSSIHMECKVSGSLPISAQW 5270
Query: 271 IR 272
+
Sbjct: 5271 FK 5272
Score = 47.8 bits (112), Expect = 2e-05
Identities = 55/232 (23%), Positives = 88/232 (37%), Gaps = 31/232 (13%)
Query: 93 ASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVG 152
A+L+ N + D G YI K N S +TV + P E VG
Sbjct: 8016 ATLVFNQVDINDSGEYICKAE---NSVGEVSASTFLTVQEQKLPPSFS-RQLRDVQETVG 8071
Query: 153 -NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTY--SFSPQNNTLHIAPVTKEDIGNYSCLV 209
+ C + G ++ W K+G+P+ S SF TL+I + G YSC
Sbjct: 8072 LPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTA 8131
Query: 210 RNPVSEMESD--IIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNT 267
NP+ S +I+ P+ +++ V V +GE+ F+C P
Sbjct: 8132 TNPIGSASSSARLILTEGKNPPF-------FDIRLAPVDAV-VGESADFECHVTGTQPIK 8183
Query: 268 YSWIRRTDNTTYIIKHGPRLEVA-SEKVAQKTM---------DYVCCAYNNI 309
SW + + I+ G + +++ E A T+ Y C A N +
Sbjct: 8184 VSWAKDSRE----IRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEV 8231
Score = 47.0 bits (110), Expect = 4e-05
Identities = 56/239 (23%), Positives = 93/239 (38%), Gaps = 32/239 (13%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQVTVDDP---VTKPV 138
++KF+ A L I+ L+ D G Y N G+ S +TV +P V KP
Sbjct: 4720 KYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSG----HLTVKEPPYFVEKPQ 4775
Query: 139 VQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF--SPQNNTLHIAP 196
Q P+ V+ L V G + +W K+ + +H+ + S + +L +
Sbjct: 4776 SQDVNPNTRVQ------LKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFA 4829
Query: 197 VTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILF 256
D G Y C + N V S + + P ++ K V + G++ F
Sbjct: 4830 AKATDSGTYICQLSNDVGTATSKATL-FVKEPPQFIK-------KPSPVLVLRNGQSTTF 4881
Query: 257 DCSADSHPPNTYSWIRRTDNTTYIIKHG-------PRLEVASEKVAQKTMDYVCCAYNN 308
+C P SW + T I KHG +++ +V + + YVC A N+
Sbjct: 4882 ECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARV-ENSGTYVCEARND 4939
Score = 45.4 bits (106), Expect = 1e-04
Identities = 66/270 (24%), Positives = 99/270 (36%), Gaps = 33/270 (12%)
Query: 93 ASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVG 152
A L + D G Y +++ N S+S + TV D P P V+ V
Sbjct: 4072 AQLKFYSAELHDSGQYTFEIS---NEVGSSSCETTFTVLDRDIAPFFT--KPLRNVDSVV 4126
Query: 153 NMT--LTCHVEGGTRLAYQWLKNGRPVHTSSTY--SFSPQNNTLHIAPVTKEDIGNYSCL 208
N T L C + G + W K+G+ + S Y +F +L I V D GN++C
Sbjct: 4127 NGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCR 4186
Query: 209 VRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
N V +S + I+ P + K V G A+ + P T
Sbjct: 4187 ATNSVGSKDSSGAL-IVQEPPSFVTKPGSK--------DVLPGSAVCLKSTFQGSTPLTI 4237
Query: 269 SWIRR-----TDNTTYIIKHGPRLEVASEKVAQKTMD---YVCCAYNNITGRQDETHFTV 320
W + + + YI K LE + E KT D Y C N G + + V
Sbjct: 4238 RWFKGNKELVSGGSCYITKEA--LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV 4295
Query: 321 IITSVGLEK-----LAQKGKSLSPLASITG 345
+ +EK L +KG + +TG
Sbjct: 4296 KEPATFVEKLEPSQLLKKGDATQLACKVTG 4325
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/209 (22%), Positives = 84/209 (40%), Gaps = 26/209 (12%)
Query: 79 DLEYQHKFTM--MPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTK 136
+++ KF M + A L ++ L D G+Y + + N SAS + V +P
Sbjct: 7345 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAH---NAAGSASSSTSLKVKEP--- 7398
Query: 137 PVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN--NTLHI 194
P+ + P ++ L C ++G W K+ R + + Y +N ++HI
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHI 7458
Query: 195 APVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAI 254
V DIG Y C N V SD + G L+ K+ ++ TV +G+ +
Sbjct: 7459 LNVDAADIGEYQCKATNDVG---SDTCV-----GSIALKAPPRFVKKLSDISTV-VGKEV 7509
Query: 255 LFDCSADSHPPNTYSW-------IRRTDN 276
+ + P + W +R +DN
Sbjct: 7510 QLQTTIEGAEPISVVWFKDKGEIVRESDN 7538
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/142 (25%), Positives = 63/142 (44%), Gaps = 11/142 (7%)
Query: 74 KSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKV-NIQGNGTLSASQKI-QVTVD 131
K +VP + F AS I + D G Y KV N G+ + A ++ +
Sbjct: 5179 KQIVPSRYFSMSFENNV--ASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIP 5236
Query: 132 DPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF--SPQN 189
TK + ++ G+ ++ + C V G ++ QW K+G+ + TS+ Y ++
Sbjct: 5237 PSFTKKLTKMDKVLGS-----SIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERS 5291
Query: 190 NTLHIAPVTKEDIGNYSCLVRN 211
+L + + ED NY+C V N
Sbjct: 5292 VSLEVNNLELEDTANYTCKVSN 5313
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/142 (25%), Positives = 57/142 (40%), Gaps = 9/142 (6%)
Query: 134 VTKPVVQIHPPSGAVEYVGN-MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN-- 190
V +P I P +G TL C V+G + W K + ++ Y +NN
Sbjct: 7016 VLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVA 7075
Query: 191 TLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDL 250
+L I V D+G YSC N V + S ++ I ++ K+ +V L
Sbjct: 7076 SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI-----KARKLPPFFARKLKDVHET-L 7129
Query: 251 GEAILFDCSADSHPPNTYSWIR 272
G + F+C + P SW +
Sbjct: 7130 GFPVAFECRINGSEPLQVSWYK 7151
Score = 42.7 bits (99), Expect = 7e-04
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 4/96 (4%)
Query: 118 GTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPV 177
GT S+S K+ ++ + P + P S + + T CHV G + W K+ R +
Sbjct: 7195 GTASSSAKLILSEHE--VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREI 7252
Query: 178 HTSSTYSFSPQNN--TLHIAPVTKEDIGNYSCLVRN 211
Y + N TL + V K D G Y+C N
Sbjct: 7253 RPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASN 7288
Score = 42.0 bits (97), Expect = 0.001
Identities = 66/288 (22%), Positives = 104/288 (36%), Gaps = 38/288 (13%)
Query: 78 PDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKP 137
P EY+ FT A+L+ N + D G Y K N +AS K + + P
Sbjct: 6121 PTPEYRTYFTNNV--ATLVFNKVNINDSGEYTCKAE---NSIGTASSKTVFRIQERQLPP 6175
Query: 138 VVQIHPPSGAVEYVG-NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHI 194
+ VG +TLTC + G + W ++G + S +N TL I
Sbjct: 6176 SFA-RQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKI 6234
Query: 195 APVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDL---- 250
G YSC NP+ S L K ++ V +
Sbjct: 6235 LQTDLSHSGQYSCSASNPLGTASSSA----------RLTAREPKKSPFFDIKPVSIDVIA 6284
Query: 251 GEAILFDCSADSHPPNTYSW------IRRTDN-TTYIIKHGPRLEVASEKVAQ-KTMDYV 302
GE+ F+C P +W IR N T + + P L + KV + + Y
Sbjct: 6285 GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRIL--KVGKGDSGQYT 6342
Query: 303 CCAYNNITGRQDETHFTV-----IITSVGLEKLAQKGKSLSPLASITG 345
C A N++ +V + + K+A++G+S+ I+G
Sbjct: 6343 CQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISG 6390
Score = 42.0 bits (97), Expect = 0.001
Identities = 47/190 (24%), Positives = 76/190 (40%), Gaps = 18/190 (9%)
Query: 87 TMMPPNASLLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPS 145
T +A L I D G Y + N G + SA Q+ + +P V Q+ P
Sbjct: 7917 TTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSA----QILILEPPYF-VKQLEPVK 7971
Query: 146 GAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHIAPVTKEDIG 203
+V + +L C + G + W K + ++TY +NN TL V D G
Sbjct: 7972 VSVG--DSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSG 8029
Query: 204 NYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLK-VGEVFTVDLGEAILFDCSADS 262
Y C N V E+ + + + L + + L+ V E +G ++FDC+
Sbjct: 8030 EYICKAENSVGEVSASTFLTV---QEQKLPPSFSRQLRDVQET----VGLPVVFDCAISG 8082
Query: 263 HPPNTYSWIR 272
P + SW +
Sbjct: 8083 SEPISVSWYK 8092
Score = 41.2 bits (95), Expect = 0.002
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 15/149 (10%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKP----- 137
+H T + ASL I + D+G Y +V N ++ + V V D + P
Sbjct: 6690 KHHITFINKVASLKIPCAEMSDKGLYSFEVK---NSVGKSNCTVSVHVSDRIVPPSFIRK 6746
Query: 138 VVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTY--SFSPQNNTLHIA 195
+ ++ GA ++ L C V G ++ W ++G + + SFS TL+++
Sbjct: 6747 LKDVNAILGA-----SVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLS 6801
Query: 196 PVTKEDIGNYSCLVRNPVSEMESDIIMPI 224
+ D G Y+C+ N E ++ +
Sbjct: 6802 LLEPSDTGIYTCVAANVAGSDECSAVLTV 6830
Score = 40.8 bits (94), Expect = 0.003
Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPV-----TKP 137
++K ++ + L I + D G Y +V N +S K ++ V D + TK
Sbjct: 4624 KYKISVTDTVSILKIISTEKKDSGEYTFEVQ---NDVGRSSCKARINVLDLIIPPSFTKK 4680
Query: 138 VVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNT--LHIA 195
+ ++ G+ + L C V G ++ QW K+ + + S Y FS +NT L I+
Sbjct: 4681 LKKMDSIKGSF-----IDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEIS 4735
Query: 196 PVTKEDIGNYSCLVRN 211
+ D G Y+C N
Sbjct: 4736 QLEGTDSGTYTCSATN 4751
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/116 (25%), Positives = 46/116 (39%), Gaps = 10/116 (8%)
Query: 109 IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPS-------GAVEYVGNMTLTCHVE 161
I V ++ +G+ S V D T+ V++ PPS + N L C V
Sbjct: 3797 ITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK-EPPSFIKTLEPADIVRGTNALLQCEVS 3855
Query: 162 GGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHIAPVTKEDIGNYSCLVRNPVSE 215
G W K+ + + +S Y Q + L I D+G Y C+V N V +
Sbjct: 3856 GTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 3911
Score = 40.0 bits (92), Expect = 0.004
Identities = 45/199 (22%), Positives = 80/199 (40%), Gaps = 23/199 (11%)
Query: 94 SLLINPLQFPDEGNYI-VKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVG 152
+L ++ L+ D G Y V N+ G+ SA +TV +P P + P S V
Sbjct: 6797 TLNLSLLEPSDTGIYTCVAANVAGSDECSAV----LTVQEP---PSFEQTPDSVEVLPGM 6849
Query: 153 NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN--NTLHIAPVTKEDIGNYSCLVR 210
++T T + G +W K R + + + S ++ L + V + G+YSCLV
Sbjct: 6850 SLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVT 6909
Query: 211 NPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
N + + + ++ F+V+ G I+ + + PP + SW
Sbjct: 6910 NDAGSASCTTHLFVKEPATFVKRLAD---------FSVETGSPIVLEATYTGTPPISVSW 6960
Query: 271 IRRTDNTTYIIKHGPRLEV 289
I+ Y+I R +
Sbjct: 6961 IK----DEYLISQSERCSI 6975
Score = 39.7 bits (91), Expect = 0.006
Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 15/184 (8%)
Query: 93 ASLLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQVTVDDPV-TKPVVQIHPPSGAVEY 150
ASL+IN + D G Y K N G SA I+ P + + +H G
Sbjct: 7075 ASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFP-- 7132
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHIAPVTKEDIGNYSCL 208
+ C + G L W K+G + + S +N TL I + IG Y+C
Sbjct: 7133 ---VAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCS 7189
Query: 209 VRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
NP+ S + + + +V LK V + LGE+ F C P
Sbjct: 7190 ASNPLGTASSSAKLILSEH-----EVPPFFDLKPVSV-DLALGESGTFKCHVTGTAPIKI 7243
Query: 269 SWIR 272
+W +
Sbjct: 7244 TWAK 7247
Score = 39.7 bits (91), Expect = 0.006
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 158 CHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLH--IAPVTKEDIGNYSCLVRNPVSE 215
CHV G + W K+ R + + Y S N+ H + V K D G Y+C N V +
Sbjct: 8174 CHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGK 8233
Score = 39.3 bits (90), Expect = 0.007
Identities = 46/182 (25%), Positives = 67/182 (36%), Gaps = 16/182 (8%)
Query: 93 ASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVG 152
A+L I + D G Y+ + N S+S VTV +P + V+ PS +
Sbjct: 3699 ATLEIPLAKLKDSGTYVCTAS---NEAGSSSCSATVTVREPPS--FVKKVDPSYLMLPGE 3753
Query: 153 NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYS--FSPQNNTLHIAPVTKEDIGNYSCLVR 210
+ L C ++G + W KN + + S+T F L I V ED G+YSC
Sbjct: 3754 SARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAV 3813
Query: 211 NPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSW 270
N V I+ P +K E + G L C P SW
Sbjct: 3814 NDVG--SDSCSTEIVIKEPPSF-------IKTLEPADIVRGTNALLQCEVSGTGPFEISW 3864
Query: 271 IR 272
+
Sbjct: 3865 FK 3866
Score = 38.9 bits (89), Expect = 0.010
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 10/86 (11%)
Query: 134 VTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNT-- 191
+TKPVVQ G+V + C V G + W K+G P+ T Y S T
Sbjct: 1085 ITKPVVQKLVEGGSVVF------GCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGE 1138
Query: 192 --LHIAPVTKEDIGNYSCLVRNPVSE 215
L I+ +D G Y+ +VRN E
Sbjct: 1139 CKLVISMTFADDAGEYTIVVRNKHGE 1164
Score = 38.9 bits (89), Expect = 0.010
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 137 PVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHI 194
P P S + N+ TC + G +W KN P+ SS S S N +L I
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 33193
Query: 195 APVTKEDIGNYSCLVRN---PVSEMESDIIMPII 225
+ D G Y+ +N S S +++P++
Sbjct: 33194 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLV 33227
Score = 38.5 bits (88), Expect = 0.013
Identities = 56/250 (22%), Positives = 89/250 (35%), Gaps = 22/250 (8%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIV-KVNIQGNGTLSASQKIQVTVDDPVTKPVVQI 141
+++ + + +A L + + D G Y VN G + +A Q+ + + + P
Sbjct: 8198 KYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTA----QLNIKERLIPPSFTK 8253
Query: 142 HPPSGAVEYVGN-MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNT--LHIAPVT 198
E GN L V G + W KN + +S + +NNT L +
Sbjct: 8254 RLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAG 8313
Query: 199 KEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDC 258
D G Y+C V N + I+ P V V TV GE + C
Sbjct: 8314 MNDAGLYTCKVSNDAG--SALCTSSIVIKEPKKPPVFDQHLTPV----TVSEGEYVQLSC 8367
Query: 259 SADSHPPNTYSW------IRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGR 312
P W I+ +D ++ G + + + DYVC A +N+ G
Sbjct: 8368 HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKA-SNVAG- 8425
Query: 313 QDETHFTVII 322
D T V I
Sbjct: 8426 SDTTKSKVTI 8435
Score = 38.5 bits (88), Expect = 0.013
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 7/107 (6%)
Query: 128 VTVDDPVTKPVVQIHPPSGA---VEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYS 184
+TV + + P V + GA V N+ L +G + + WLK+G P+ S
Sbjct: 27552 ITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 27611
Query: 185 FSPQNN--TLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGP 229
FS N TL I KE G Y+ ++ N V + + + +I GP
Sbjct: 27612 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIA--VPITVITLGP 27656
Score = 37.0 bits (84), Expect = 0.037
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 37/194 (19%)
Query: 134 VTKPVVQIHPPSGAVEYVGN-MTLTCHVEGGTRLAYQWLKNGRPVHTSSTY--SFSPQNN 190
V +P I P GN L C V G L+ +W K+GR + S + +F +
Sbjct: 6641 VLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVA 6700
Query: 191 TLHIAPVTKEDIGNYSCLVRNPVSEME-------SDIIMPIIYYGPYGLQVNSDKGLKVG 243
+L I D G YS V+N V + SD I+P + K+
Sbjct: 6701 SLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFI------------RKLK 6748
Query: 244 EVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVA-SEKVAQKTMD-- 300
+V + LG +++ +C P + W + + I GP+ + + SE V +
Sbjct: 6749 DVNAI-LGASVVLECRVSGSAPISVGWFQDGNE----IVSGPKCQSSFSENVCTLNLSLL 6803
Query: 301 -------YVCCAYN 307
Y C A N
Sbjct: 6804 EPSDTGIYTCVAAN 6817
Score = 37.0 bits (84), Expect = 0.037
Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 95 LLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNM 154
L+IN QF DEG Y +V + I++ P+ V+ +
Sbjct: 11541 LVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETA--------- 11591
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNT--LHIAPVTKEDIGNYSCLVRNP 212
T C + ++ W KN +HTS T S + T L + VT +DI ++
Sbjct: 11592 TFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQ----IKAQ 11646
Query: 213 VSEMESDIIMPIIYYGPY 230
V E+ S + ++ PY
Sbjct: 11647 VKELSSTAQLKVLEADPY 11664
Score = 36.6 bits (83), Expect = 0.048
Identities = 50/248 (20%), Positives = 86/248 (34%), Gaps = 41/248 (16%)
Query: 40 PVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINP 99
P + +D+++ W S +K + P + + T L I
Sbjct: 3361 PARFQCRVSGTDLKVSWY-------------SKDKKIKPSRFF--RMTQFEDTYQLEIAE 3405
Query: 100 LQFPDEGNY-------IVKVNIQGNGTLSASQKI------QVTVDDPVTKPVVQ--IHPP 144
DEG Y + +V+ N +L A + I Q + PV++ I P
Sbjct: 3406 AYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPL 3465
Query: 145 SGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF--SPQNNTLHIAPVTKEDI 202
A+ ++ T C ++ + +QW K GR ++ S S S ++L I D
Sbjct: 3466 EVALGHLAKFT--CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 3523
Query: 203 GNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADS 262
G Y+C N + + + P L + T +G+A F C+
Sbjct: 3524 GEYTCKASNEYGSVSCTATLTVTEAYP-------PTFLSRPKSLTTFVGKAAKFICTVTG 3576
Query: 263 HPPNTYSW 270
P W
Sbjct: 3577 TPVIETIW 3584
Score = 36.2 bits (82), Expect = 0.062
Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 22/108 (20%)
Query: 120 LSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHT 179
+ ++ IQVT DP T +EY V G L +W K+GRP+
Sbjct: 4020 IERAELIQVTAGDPAT------------LEYT--------VAGTPELKPKWYKDGRPLVA 4059
Query: 180 SSTYSFSPQNNTLHIAPVTKE--DIGNYSCLVRNPVSEMESDIIMPII 225
S Y S +NN + + E D G Y+ + N V + ++
Sbjct: 4060 SKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVL 4107
Score = 36.2 bits (82), Expect = 0.062
Identities = 30/123 (24%), Positives = 50/123 (40%), Gaps = 8/123 (6%)
Query: 93 ASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVG 152
ASL ++ ++ +G Y+ + G S + V +T+ V I G
Sbjct: 4541 ASLYLSGIEVKHDGKYVCQAKNDA-GIQRCSALLSVKEPATITEEAVSIDVTQG-----D 4594
Query: 153 NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN--NTLHIAPVTKEDIGNYSCLVR 210
TL G + +W K+G+ + S Y S + + L I K+D G Y+ V+
Sbjct: 4595 PATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQ 4654
Query: 211 NPV 213
N V
Sbjct: 4655 NDV 4657
Score = 35.8 bits (81), Expect = 0.081
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSP--QNNTLHIAPVTKEDIGNYSCLVRNPV 213
L+C + G +W + G+ + S Y S + +TL + +ED G Y+C+ N V
Sbjct: 30552 LSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEV 30611
Query: 214 SEMES 218
E+E+
Sbjct: 30612 GEVET 30616
Score = 35.0 bits (79), Expect = 0.14
Identities = 32/155 (20%), Positives = 57/155 (36%), Gaps = 5/155 (3%)
Query: 76 VVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVT 135
VV L ++K+ + + SL + + Y +V+ + +I V D V
Sbjct: 19919 VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVV 19978
Query: 136 KPVVQIHPPSGAVEYV---GNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF--SPQNN 190
P + + N L ++G + W K P+ T + S S N
Sbjct: 19979 APDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT 20038
Query: 191 TLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPII 225
TL + K D G Y+ ++N E I + ++
Sbjct: 20039 TLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 20073
Score = 34.3 bits (77), Expect = 0.24
Identities = 37/182 (20%), Positives = 65/182 (35%), Gaps = 17/182 (9%)
Query: 147 AVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNT--LHIAPVTKEDIGN 204
+VE ++ L G ++ W K+G + TS + T L I TK D G
Sbjct: 5996 SVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQ 6055
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHP 264
YSC + N ++ + + ++ E +G+++ C P
Sbjct: 6056 YSCEIENEAGRDVCGALVSTLEPPYFVTEL---------EPLEAAVGDSVSLQCQVAGTP 6106
Query: 265 PNTYSW------IRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHF 318
T SW +R T + V ++ + +Y C A N+I +T F
Sbjct: 6107 EITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 6166
Query: 319 TV 320
+
Sbjct: 6167 RI 6168
Score = 34.3 bits (77), Expect = 0.24
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 149 EYVGNMTL-TCHVEGGTRLAYQWLKNGRPVHTSSTYSF--SPQNNTLHIAPVTKEDIGNY 205
E+VG+ + C V T + W+K+G + S + F ++ LHI V D G Y
Sbjct: 11130 EFVGSSAIFECLVSPSTAIT-TWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEY 11188
Query: 206 SCLVR 210
+C++R
Sbjct: 11189 TCVLR 11193
Score = 33.9 bits (76), Expect = 0.31
Identities = 28/128 (21%), Positives = 50/128 (39%), Gaps = 11/128 (8%)
Query: 147 AVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFS--PQNNTLHIAPVTKEDIGN 204
+VE + L G ++ W+K+ + S S + ++ L I T ED
Sbjct: 6937 SVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQ 6996
Query: 205 YSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHP 264
YSCL+ N + + ++ ++ PY ++ +GE T+ C D P
Sbjct: 6997 YSCLIENEAGQDICEALVSVL-EPPYFIEPLEHVEAVIGEPATL--------QCKVDGTP 7047
Query: 265 PNTYSWIR 272
SW +
Sbjct: 7048 EIRISWYK 7055
Score = 33.9 bits (76), Expect = 0.31
Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
Query: 109 IVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAY 168
+V VN +G S + + D V +P V+ S +V+ ++ + + G +
Sbjct: 23203 VVAVNEKGRSD-PRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTI 23261
Query: 169 QWLKNGRPVH--TSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDI 220
W K+G P+ T + S TL I K+D G Y V N V + + I
Sbjct: 23262 TWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 23315
Score = 33.5 bits (75), Expect = 0.40
Identities = 21/107 (19%), Positives = 44/107 (41%), Gaps = 2/107 (1%)
Query: 120 LSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHT 179
++ + ++ V+ PVT P + + V ++TL CH+ G W + + +
Sbjct: 926 VTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIES 985
Query: 180 SSTYSFSPQNN--TLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPI 224
S + + Q+ L I ED G ++C N + + + +
Sbjct: 986 SIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 33.5 bits (75), Expect = 0.40
Identities = 39/198 (19%), Positives = 70/198 (35%), Gaps = 17/198 (8%)
Query: 83 QHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIH 142
+H+ + + A L + + D G Y+ + + G+ S + V TK +
Sbjct: 4345 KHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEA-GSDHCSSIVIVKESPYFTK---EFK 4400
Query: 143 PPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNN--TLHIAPVTKE 200
P EY ++ L V G W K+ + + Y Q++ +L I
Sbjct: 4401 PIEVLKEY--DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAA 4458
Query: 201 DIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSA 260
D G Y C V N V + + + ++ S L+ G F +
Sbjct: 4459 DAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLR---------GGTAAFQATL 4509
Query: 261 DSHPPNTYSWIRRTDNTT 278
P T +W++ +D T
Sbjct: 4510 KGSLPITVTWLKDSDEIT 4527
Score = 32.3 bits (72), Expect = 0.90
Identities = 35/146 (23%), Positives = 53/146 (36%), Gaps = 35/146 (23%)
Query: 95 LLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNM 154
L I FPDEG YIV D ++ I P+ VE++ +
Sbjct: 12790 LTIKDCGFPDEGEYIVTAG-----------------QDKSVAELLIIEAPTEFVEHLEDQ 12832
Query: 155 TLT--------CHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN--NTLHIAPVTKEDIGN 204
T+T C + + +W +NGR + Y F + L I +D
Sbjct: 12833 TVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECE 12891
Query: 205 YSCLVRNP-------VSEMESDIIMP 223
Y+C V + V E+ +II P
Sbjct: 12892 YACGVEDRKSRARLFVEEIPVEIIRP 12917
Score = 32.0 bits (71), Expect = 1.2
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 9/64 (14%)
Query: 170 WLKNGRPVHTSSTYSF--SPQNNTLHIAPVTKEDIGNYSCLV-------RNPVSEMESDI 220
W+K+G+ V S Q++ L I +TKED GNYS + VS D+
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2447
Query: 221 IMPI 224
I P+
Sbjct: 2448 ITPL 2451
Score = 31.6 bits (70), Expect = 1.5
Identities = 35/154 (22%), Positives = 54/154 (35%), Gaps = 18/154 (11%)
Query: 86 FTMMPPNASLLINPLQFPDEGNYIVKV-NIQGNGTLSASQKIQVTVDDPVTKPVVQIHPP 144
F+ A L + + D G+Y+ K N+ G+ T + I+ D P P +
Sbjct: 8394 FSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK---DKPAVAPATKKAAV 8450
Query: 145 SGAVEYVGN-----------MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNT-- 191
G + +V T V G +W K F Q
Sbjct: 8451 DGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEA 8510
Query: 192 -LHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPI 224
L I TK D G Y C+ N E+ES++ + +
Sbjct: 8511 KLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 31.2 bits (69), Expect = 2.0
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 4/93 (4%)
Query: 123 SQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSS- 181
S+ I D P+ P + + V Y N TL C V G + +W + G+ +
Sbjct: 30914 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 30973
Query: 182 ---TYSFSPQNNTLHIAPVTKEDIGNYSCLVRN 211
F + L IA VT +D Y N
Sbjct: 30974 KYRIQEFKGGYHQLIIASVTDDDATVYQVRATN 31006
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/88 (25%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 139 VQIHPPSGAVEYV-----GNMTLTCHVEGGTRLAY-QWLKNGRPVHTSSTYSFSPQNNT- 191
++I P SG + + G++ C +E + W R + S Y + ++
Sbjct: 31565 IEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVA 31624
Query: 192 -LHIAPVTKEDIGNYSCLVRNPVSEMES 218
L++ +TK D G Y C V N E S
Sbjct: 31625 ILYVKDITKLDDGTYRCKVVNDYGEDSS 31652
Score = 30.0 bits (66), Expect = 4.5
Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 4/61 (6%)
Query: 155 TLTCHVEGGTRLAYQWLKNGRPVHTSST----YSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
T H+ G W ++G+ + TS+ SFS L I VTK + G YS
Sbjct: 24 TFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKAT 83
Query: 211 N 211
N
Sbjct: 84 N 84
Score = 30.0 bits (66), Expect = 4.5
Identities = 18/88 (20%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Query: 126 IQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF 185
+ V D +P +++ + +++ ++ + V G R W+K+G P+ ++ +
Sbjct: 24301 VPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV 24360
Query: 186 --SPQNNTLHIAPVTKEDIGNYSCLVRN 211
+ + LHI K+D G Y+ N
Sbjct: 24361 EETATSTVLHIKEGNKDDFGKYTVTATN 24388
Score = 30.0 bits (66), Expect = 4.5
Identities = 21/102 (20%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 126 IQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSF 185
+ V D KP V++ + V+ + + +G + W K+G+ + ++ +
Sbjct: 25384 VPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNV 25443
Query: 186 SPQNN--TLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPII 225
S +L I +KED+G Y V N + I + ++
Sbjct: 25444 SSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVL 25485
Score = 29.6 bits (65), Expect = 5.8
Identities = 23/107 (21%), Positives = 38/107 (35%), Gaps = 3/107 (2%)
Query: 121 SASQKIQVTVDDPVT-KPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHT 179
+ ++K + +P++ KPV+ V G R W K+G+ +
Sbjct: 32835 TVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQ 32894
Query: 180 SSTYSFSPQNNT--LHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPI 224
Y S L I D G Y+C V+N + S + I
Sbjct: 32895 GGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 32941
Score = 29.3 bits (64), Expect = 7.6
Identities = 14/59 (23%), Positives = 26/59 (44%), Gaps = 2/59 (3%)
Query: 156 LTCHVEGGTRLAYQWLKNGRPVHTSSTY--SFSPQNNTLHIAPVTKEDIGNYSCLVRNP 212
L C + G + W +N + S Y +F + + ++ ED G++ C +NP
Sbjct: 5443 LECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNP 5501
Score = 29.3 bits (64), Expect = 7.6
Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 12/116 (10%)
Query: 160 VEGGTRLAYQWLKN-GRPVHTSSTY--SFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEM 216
+EG ++ W K+ G V S S+S TL + V + G Y+C ++N
Sbjct: 7515 IEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQ 7574
Query: 217 ESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIR 272
E + ++ ++ E V G+ +C+ P + W +
Sbjct: 7575 ECFATLSVLEPATI---------VEKPESIKVTTGDTCTLECTVAGTPELSTKWFK 7621
Score = 29.3 bits (64), Expect = 7.6
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 170 WLKNGRPVHTSSTYSF--SPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYY 227
W K+ + + + + YS + ++ L I VT+ D G Y + N V E +S + +
Sbjct: 27305 WRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLD 27364
Query: 228 GPYGLQVNSDKGLKVGEV 245
P Q K + G V
Sbjct: 27365 TPAACQKLQVKHVSRGTV 27382
Score = 29.3 bits (64), Expect = 7.6
Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 4/79 (5%)
Query: 137 PVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQN----NTL 192
P ++ P +++ +T+ C G W GR +H+ F +N TL
Sbjct: 33329 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 33388
Query: 193 HIAPVTKEDIGNYSCLVRN 211
I V K+D G Y+ + N
Sbjct: 33389 IIMDVQKQDGGLYTLSLGN 33407
>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
isoform 2 [Homo sapiens]
Length = 292
Score = 63.5 bits (153), Expect = 4e-10
Identities = 41/137 (29%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
P+ L + D G Y ++V + + AS ++V + V +P +Q S V
Sbjct: 103 PSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVY--ESVAQPSIQAS--STTVTE 158
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
G++ LTCH T ++QW+ N + + + S N+ L I P+ +ED G Y C V
Sbjct: 159 KGSVVLTCHTNN-TGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVS 217
Query: 211 NPVSEMESDIIMPIIYY 227
NPVS SD + + Y
Sbjct: 218 NPVSSNRSDPLKLTVKY 234
>gi|148612793 carcinoembryonic antigen-related cell adhesion
molecule isoform 1 [Homo sapiens]
Length = 293
Score = 63.2 bits (152), Expect = 5e-10
Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 14/147 (9%)
Query: 91 PNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEY 150
P+ L + D G Y ++V + + AS ++V + V +P +Q S V
Sbjct: 103 PSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVY--ESVAQPSIQAS--STTVTE 158
Query: 151 VGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVR 210
G++ LTCH T ++QW+ N + + + S N+ L I P+ +ED G Y C V
Sbjct: 159 KGSVVLTCHTNN-TGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVS 217
Query: 211 NPVSEMESDIIMPIIYYGPYGLQVNSD 237
NPVS SD P L V SD
Sbjct: 218 NPVSSNRSD---------PLKLTVKSD 235
>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
16 [Homo sapiens]
Length = 484
Score = 62.8 bits (151), Expect = 6e-10
Identities = 74/315 (23%), Positives = 122/315 (38%), Gaps = 28/315 (8%)
Query: 2 WLKVFTTFLSFATGACSGLKVTVPSH------TVHGVRGQALYLPVHYGFHTPASDIQII 55
WL + TFL+ L+ PS VHG+ G+ L + G P + +
Sbjct: 67 WLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAG---PTLSVSYL 123
Query: 56 WLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQ 115
+ Y++ + +++ P + + P+ SL I + G YI++ +
Sbjct: 124 --------VASYIVSTGDETPGPAHTGREA---VRPDGSLDIQGILPRHSGTYILQTFNR 172
Query: 116 GNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGR 175
T +QV + + +P V + + VE + L C T +W NG
Sbjct: 173 QLQTEVGYGHVQV--HEILAQPTVLANS-TALVERRDTLRLMCSSPSPTA-EVRWFFNGG 228
Query: 176 PVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVN 235
+ + SP L + +E+ G Y C V NPVS S+ I +Y+GP + +
Sbjct: 229 ALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAIL 288
Query: 236 SDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVA 295
D + G VD ++ C + S P Y W T N + L ++S A
Sbjct: 289 QDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVW---TFNGQALKNGQDHLNISSMTAA 345
Query: 296 QKTMDYVCCAYNNIT 310
Q+ Y C A N T
Sbjct: 346 QEG-TYTCIAKNTKT 359
>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
Length = 426
Score = 61.2 bits (147), Expect = 2e-09
Identities = 64/276 (23%), Positives = 108/276 (39%), Gaps = 19/276 (6%)
Query: 48 PASDIQIIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGN 107
P ++ + L P T L +N +P H + N +L + + G
Sbjct: 158 PRETMEAVSLTCDPETPDASYLWWMNGQSLP---MTHSLKLSETNRTLFLLGVTKYTAGP 214
Query: 108 YIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLA 167
Y + I+ + S S + + + + KP + I+ + E + TC +
Sbjct: 215 Y--ECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPR-ENKDVLNFTCEPKS-ENYT 270
Query: 168 YQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYY 227
Y W NG+ + S +N L + VT+ + G Y C +R+ + SD + + Y
Sbjct: 271 YIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLY 330
Query: 228 GPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRL 287
GP D GE + CSADS+PP YSW T N + + G +L
Sbjct: 331 GP-------DLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSW---TINEKFQLP-GQKL 379
Query: 288 EVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIIT 323
+ + YVC N+ TG++ TV ++
Sbjct: 380 FIRHITTKHSGL-YVCSVRNSATGKESSKSMTVEVS 414
Score = 58.9 bits (141), Expect = 9e-09
Identities = 55/203 (27%), Positives = 87/203 (42%), Gaps = 12/203 (5%)
Query: 21 KVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSV--NKSVVP 78
+VT+ + G+ + L VH + P + IW + + Y+ V + ++
Sbjct: 35 QVTIEAEPTKVSEGKDVLLLVH---NLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIY 91
Query: 79 DLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPV 138
Y + T NASLLI + D G+Y + + +GT + + T+ KP
Sbjct: 92 GPAYSGRETAYS-NASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPS 150
Query: 139 VQIHP--PSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAP 196
+ P +E V +LTC E +Y W NG+ + + + S N TL +
Sbjct: 151 ISSSNLNPRETMEAV---SLTCDPETPDA-SYLWWMNGQSLPMTHSLKLSETNRTLFLLG 206
Query: 197 VTKEDIGNYSCLVRNPVSEMESD 219
VTK G Y C +RNPVS SD
Sbjct: 207 VTKYTAGPYECEIRNPVSASRSD 229
Score = 28.9 bits (63), Expect = 9.9
Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 25/110 (22%)
Query: 132 DPVTKPVV------QIHPP-----SGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTS 180
DPVT V+ +I+P SG V Y L+C + Y W N +
Sbjct: 322 DPVTLNVLYGPDLPRIYPSFTYYRSGEVLY-----LSCSADSNPPAQYSWTINEK----- 371
Query: 181 STYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPY 230
F L I +T + G Y C VRN + ES M + G +
Sbjct: 372 ----FQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSGKW 417
>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
sapiens]
Length = 435
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 8/131 (6%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQ---IHPPSGAV 148
NASLLI + D G+Y + + +G+GT + VT+ KP + ++P
Sbjct: 103 NASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPR---- 158
Query: 149 EYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCL 208
E + + L C E +Y WL NG+ + + S N TL++ VTK G Y C
Sbjct: 159 EVMEAVRLICDPETPDA-SYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECE 217
Query: 209 VRNPVSEMESD 219
+RNPVS SD
Sbjct: 218 IRNPVSASRSD 228
Score = 49.3 bits (116), Expect = 7e-06
Identities = 42/181 (23%), Positives = 70/181 (38%), Gaps = 13/181 (7%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+ TC + Y W NG+ + S +N L + VT+ + G Y C +R+
Sbjct: 257 LAFTCEPKS-RNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRY 315
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR 273
+ S+ + + YGP D GE + C ADS+PP YSW
Sbjct: 316 GGIRSNPVTLNVLYGP-------DLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSW--- 365
Query: 274 TDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEKLAQK 333
T N + + G +L + + Y C N+ TG++ V ++ ++
Sbjct: 366 TINGKFQLS-GQKLFIPQITTNHSGL-YACSVRNSATGKEISKSMIVKVSETASPQVTYA 423
Query: 334 G 334
G
Sbjct: 424 G 424
Score = 32.0 bits (71), Expect = 1.2
Identities = 18/65 (27%), Positives = 25/65 (38%), Gaps = 9/65 (13%)
Query: 153 NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNP 212
N+ L+C + Y W NG+ F L I +T G Y+C VRN
Sbjct: 348 NLDLSCFADSNPPAEYSWTINGK---------FQLSGQKLFIPQITTNHSGLYACSVRNS 398
Query: 213 VSEME 217
+ E
Sbjct: 399 ATGKE 403
>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
[Homo sapiens]
Length = 424
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 8/131 (6%)
Query: 92 NASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQ---IHPPSGAV 148
NASLLI + D G+Y + + +G+GT + VT+ KP + ++P
Sbjct: 103 NASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPR---- 158
Query: 149 EYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCL 208
E + + L C E +Y WL NG+ + + S N TL++ VTK G Y C
Sbjct: 159 EVMEAVRLICDPETPDA-SYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECE 217
Query: 209 VRNPVSEMESD 219
+RNPVS SD
Sbjct: 218 IRNPVSASRSD 228
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/160 (25%), Positives = 64/160 (40%), Gaps = 13/160 (8%)
Query: 154 MTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPV 213
+ TC + Y W NG+ + S +N L + VT+ + G Y C +R+
Sbjct: 257 LAFTCEPKS-RNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRY 315
Query: 214 SEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRR 273
+ S+ + + YGP D GE + C ADS+PP YSW
Sbjct: 316 GGIRSNPVTLNVLYGP-------DLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSW--- 365
Query: 274 TDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQ 313
T N + + G +L + + Y C N+ TG++
Sbjct: 366 TINGKFQLS-GQKLFIPQITTNHSGL-YACSVRNSATGKE 403
Score = 34.7 bits (78), Expect = 0.18
Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
Query: 153 NMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNP 212
N+ L+C + Y W NG+ F L I +T G Y+C VRN
Sbjct: 348 NLDLSCFADSNPPAEYSWTINGK---------FQLSGQKLFIPQITTNHSGLYACSVRNS 398
Query: 213 VSEMESDIIMPIIYYGP-YGLQVNS 236
+ E M + GP +G Q S
Sbjct: 399 ATGKEISKSMIVKVSGPCHGNQTES 423
>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
[Homo sapiens]
Length = 213
Score = 60.5 bits (145), Expect = 3e-09
Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 14/184 (7%)
Query: 149 EYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCL 208
E + + LTC+ E +Y W NG+ + + S N TL + VTK G Y C
Sbjct: 38 EAMETVILTCNPETPDA-SYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECE 96
Query: 209 VRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTY 268
+ N S SD + + +GP D V + GE + C A+S+PP Y
Sbjct: 97 IWNSGSASRSDPVTLNLLHGP-------DLPRIFPSVTSYYSGENLDLSCFANSNPPAQY 149
Query: 269 SWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTV-IITSVGL 327
SW T N + + G +L + + Y C A N+ TG + T T+ +I GL
Sbjct: 150 SW---TINGKFQLS-GQKLFIPQITPKHNGL-YACSARNSATGEESSTSLTIRVIAPPGL 204
Query: 328 EKLA 331
A
Sbjct: 205 GTFA 208
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,520,157
Number of Sequences: 37866
Number of extensions: 851038
Number of successful extensions: 3445
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 204
Number of HSP's that attempted gapping in prelim test: 1927
Number of HSP's gapped (non-prelim): 1123
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.