Guide to the Human Genome
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Name: PIK3C3 Sequence: fasta or formatted (887aa) NCBI GI: 34761064
Description:

catalytic phosphatidylinositol 3-kinase 3

Referenced in:

Inositol Pathways
Additional Membrane Functions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         46           2
 C cysteine            1.4         12           1
 D aspartate           6.5         58           2
 E glutamate           6.9         61           2
 F phenylalanine       3.6         32           2
 G glycine             4.7         42           2
 H histidine           2.0         18           2
 I isoleucine          4.2         37           2
 K lysine              8.1         72           3
 L leucine            11.5        102           3
 M methionine          3.0         27           1
 N asparagine          3.9         35           1
 P proline             5.2         46           3
 Q glutamine           5.1         45           2
 R arginine            4.6         41           2
 S serine              7.1         63           2
 T threonine           4.8         43           2
 V valine              6.7         59           2
 W tryptophan          1.2         11           1
 Y tyrosine            4.2         37           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   catalytic phosphatidylinositol 3-kinase 3 
PIK3CG                0.093   phosphoinositide-3-kinase, catalytic, gamma polypept...
PIK3CD                0.088   catalytic phosphatidylinositol 3-kinase delta [Homo...
PIK3C2G               0.086   phosphoinositide-3-kinase, class 2 gamma polypeptid...
PIK3C2A               0.084   phosphoinositide-3-kinase, class 2 alpha polypeptid...
PIK3CB                0.083   catalytic phosphatidylinositol 3-kinase beta 
PIK3CA                0.079   phosphoinositide-3-kinase, catalytic, alpha polypept...
PIK3C2B               0.077   phosphoinositide-3-kinase, class 2 beta polypeptide...
PI4KB                 0.053   catalytic phosphatidylinositol 4-kinase beta 
PI4KA                 0.052   phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...
PI4KA                 0.052   phosphatidylinositol 4-kinase type 3 alpha isoform ...
LOC100293141          0.032   PREDICTED: similar to phosphatidylinositol 4-kinase...
ATM                   0.027   ataxia telangiectasia mutated isoform 2 
ATM                   0.027   ataxia telangiectasia mutated isoform 1 
MTOR                  0.027   FK506 binding protein 12-rapamycin associated protein...
LOC651610             0.027   PREDICTED: similar to Serine-protein kinase ATM, pa...
PRKDC                 0.024   protein kinase, DNA-activated, catalytic polypeptid...
LOC731751             0.024   PREDICTED: similar to protein kinase, DNA-activated...
ATR                   0.021   ataxia telangiectasia and Rad3 related protein [Hom...
LOC648152             0.021   PREDICTED: similar to ataxia telangiectasia and Rad...
SMG1                  0.016   PI-3-kinase-related kinase SMG-1 
PRKDC                 0.014   protein kinase, DNA-activated, catalytic polypeptide...
TSG101                0.006   tumor susceptibility gene 101 
ERC2                  0.005   cytomatrix protein p110 
C15orf27              0.004   hypothetical protein LOC123591 
TMEM99                0.004   transmembrane protein 99 
AXIN1                 0.003   axin 1 isoform a 
AXIN1                 0.003   axin 1 isoform b 
STRN4                 0.003   zinedin isoform 2 
STRN4                 0.003   zinedin isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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