Guide to the Human Genome
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Name: PIK3CD Sequence: fasta or formatted (1044aa) NCBI GI: 156564405
Description:

catalytic phosphatidylinositol 3-kinase delta

Referenced in:

Inositol Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         68           3
 C cysteine            2.9         30           1
 D aspartate           4.4         46           2
 E glutamate           7.8         81           3
 F phenylalanine       4.5         47           1
 G glycine             4.7         49           2
 H histidine           3.0         31           2
 I isoleucine          3.5         37           2
 K lysine              6.4         67           3
 L leucine            13.6        142           3
 M methionine          2.7         28           1
 N asparagine          3.6         38           2
 P proline             5.2         54           3
 Q glutamine           5.0         52           2
 R arginine            5.4         56           2
 S serine              6.4         67           3
 T threonine           4.0         42           1
 V valine              5.9         62           3
 W tryptophan          1.7         18           1
 Y tyrosine            2.8         29           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   catalytic phosphatidylinositol 3-kinase delta [Homo... 
PIK3CB                0.551   catalytic phosphatidylinositol 3-kinase beta 
PIK3CA                0.342   phosphoinositide-3-kinase, catalytic, alpha polypept...
PIK3CG                0.225   phosphoinositide-3-kinase, catalytic, gamma polypept...
PIK3C2A               0.161   phosphoinositide-3-kinase, class 2 alpha polypeptid...
PIK3C2B               0.158   phosphoinositide-3-kinase, class 2 beta polypeptide...
PIK3C2G               0.129   phosphoinositide-3-kinase, class 2 gamma polypeptid...
PIK3C3                0.074   catalytic phosphatidylinositol 3-kinase 3 
PI4KA                 0.041   phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...
PI4KA                 0.041   phosphatidylinositol 4-kinase type 3 alpha isoform ...
PI4KB                 0.036   catalytic phosphatidylinositol 4-kinase beta 
LOC100293141          0.024   PREDICTED: similar to phosphatidylinositol 4-kinase...
PRKDC                 0.023   protein kinase, DNA-activated, catalytic polypeptide...
MTOR                  0.019   FK506 binding protein 12-rapamycin associated protein...
PRKDC                 0.017   protein kinase, DNA-activated, catalytic polypeptid...
LOC731751             0.017   PREDICTED: similar to protein kinase, DNA-activated...
ATM                   0.013   ataxia telangiectasia mutated isoform 2 
ATM                   0.013   ataxia telangiectasia mutated isoform 1 
LOC651610             0.013   PREDICTED: similar to Serine-protein kinase ATM, pa...
ATR                   0.011   ataxia telangiectasia and Rad3 related protein [Hom...
LOC648152             0.011   PREDICTED: similar to ataxia telangiectasia and Rad...
SMG1                  0.008   PI-3-kinase-related kinase SMG-1 
SATB2                 0.004   SATB homeobox 2 
REST                  0.004   RE1-silencing transcription factor 
ARHGAP6               0.004   Rho GTPase activating protein 6 isoform 4 
ARHGAP6               0.004   Rho GTPase activating protein 6 isoform 1 
EAF1                  0.004   ELL associated factor 1 
C15orf54              0.003   hypothetical protein LOC400360 
LOC388553             0.003   PREDICTED: similar to hCG1645909 
LOC388553             0.003   PREDICTED: similar to hCG1645909 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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