PIK3CA 32727

Name: PIK3CA	Sequence: fasta or formatted (1068aa)		NCBI GI: 54792082
Description: phosphoinositide-3-kinase, catalytic, alpha polypeptide		Referenced in: Inositol Pathways
Composition: Amino acid Percentage Count Longest homopolymer A alanine 4.2 45 2 C cysteine 3.0 32 1 D aspartate 5.4 58 2 E glutamate 7.1 76 2 F phenylalanine 4.1 44 3 G glycine 4.6 49 2 H histidine 2.8 30 2 I isoleucine 6.6 71 2 K lysine 6.7 72 4 L leucine 11.8 126 3 M methionine 3.7 39 2 N asparagine 5.2 56 2 P proline 4.8 51 2 Q glutamine 4.5 48 1 R arginine 5.5 59 2 S serine 5.4 58 2 T threonine 3.7 40 2 V valine 5.2 56 2 W tryptophan 1.8 19 1 Y tyrosine 3.7 39 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 phosphoinositide-3-kinase, catalytic, alpha polypept... PIK3CD 0.330 catalytic phosphatidylinositol 3-kinase delta [Homo... PIK3CB 0.327 catalytic phosphatidylinositol 3-kinase beta PIK3CG 0.236 phosphoinositide-3-kinase, catalytic, gamma polypept... PIK3C2B 0.165 phosphoinositide-3-kinase, class 2 beta polypeptide... PIK3C2A 0.161 phosphoinositide-3-kinase, class 2 alpha polypeptid... PIK3C2G 0.132 phosphoinositide-3-kinase, class 2 gamma polypeptid... PIK3C3 0.064 catalytic phosphatidylinositol 3-kinase 3 PI4KA 0.059 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ... PI4KA 0.059 phosphatidylinositol 4-kinase type 3 alpha isoform ... PI4KB 0.041 catalytic phosphatidylinositol 4-kinase beta LOC100293141 0.027 PREDICTED: similar to phosphatidylinositol 4-kinase... MTOR 0.014 FK506 binding protein 12-rapamycin associated protein... PRKDC 0.010 protein kinase, DNA-activated, catalytic polypeptid... LOC731751 0.010 PREDICTED: similar to protein kinase, DNA-activated... ATM 0.009 ataxia telangiectasia mutated isoform 2 ATM 0.009 ataxia telangiectasia mutated isoform 1 LOC651610 0.009 PREDICTED: similar to Serine-protein kinase ATM, pa... PRKDC 0.009 protein kinase, DNA-activated, catalytic polypeptide... ATR 0.008 ataxia telangiectasia and Rad3 related protein [Hom... LOC648152 0.008 PREDICTED: similar to ataxia telangiectasia and Rad... SMG1 0.007 PI-3-kinase-related kinase SMG-1 LARP4 0.004 c-Mpl binding protein isoform a LARP4 0.004 c-Mpl binding protein isoform c AP4B1 0.003 adaptor-related protein complex 4, beta 1 subunit [... WASF3 0.003 WAS protein family, member 3 FBXO46 0.003 F-box protein 46 KIN 0.003 HsKin17 protein ARMCX2 0.003 ALEX2 protein ARMCX2 0.003 ALEX2 protein Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.