Guide to the Human Genome
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Name: PRKDC Sequence: fasta or formatted (4097aa) NCBI GI: 126032350
Description:

protein kinase, DNA-activated, catalytic polypeptide isoform 2

Referenced in:

DNases, Recombination, and DNA Repair
Serine / Threonine Protein Phosphatases
Additional Serine / Threonine Protein Kinases
p53 Pathway

Other entries for this name:
alt prot [4128aa] protein kinase, DNA-activated, catalytic polypeptide isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5        268           4
 C cysteine            2.1         87           2
 D aspartate           5.1        208           2
 E glutamate           7.1        292           3
 F phenylalanine       4.8        196           2
 G glycine             4.5        186           3
 H histidine           2.2         90           2
 I isoleucine          4.8        198           3
 K lysine              6.7        274           3
 L leucine            12.7        522           3
 M methionine          2.9        117           2
 N asparagine          3.7        151           2
 P proline             4.6        187           2
 Q glutamine           4.6        187           3
 R arginine            5.2        214           3
 S serine              8.0        326           3
 T threonine           4.4        180           3
 V valine              6.1        249           3
 W tryptophan          1.2         48           2
 Y tyrosine            2.9        117           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   protein kinase, DNA-activated, catalytic polypeptid... 
LOC731751             0.998   PREDICTED: similar to protein kinase, DNA-activated...
PRKDC                 0.998   protein kinase, DNA-activated, catalytic polypeptide...
ATR                   0.014   ataxia telangiectasia and Rad3 related protein [Hom...
LOC648152             0.014   PREDICTED: similar to ataxia telangiectasia and Rad...
MTOR                  0.014   FK506 binding protein 12-rapamycin associated protein...
ATM                   0.011   ataxia telangiectasia mutated isoform 2 
ATM                   0.011   ataxia telangiectasia mutated isoform 1 
LOC651610             0.011   PREDICTED: similar to Serine-protein kinase ATM, pa...
SMG1                  0.009   PI-3-kinase-related kinase SMG-1 
PIK3C3                0.005   catalytic phosphatidylinositol 3-kinase 3 
TRRAP                 0.005   transformation/transcription domain-associated protei...
PIK3CG                0.005   phosphoinositide-3-kinase, catalytic, gamma polypept...
PIK3CD                0.004   catalytic phosphatidylinositol 3-kinase delta [Homo...
PIK3CB                0.004   catalytic phosphatidylinositol 3-kinase beta 
LOC651921             0.003   PREDICTED: similar to ataxia telangiectasia and Rad...
PI4KB                 0.003   catalytic phosphatidylinositol 4-kinase beta 
PIK3CA                0.003   phosphoinositide-3-kinase, catalytic, alpha polypept...
PIK3C2G               0.003   phosphoinositide-3-kinase, class 2 gamma polypeptid...
PIK3C2B               0.002   phosphoinositide-3-kinase, class 2 beta polypeptide...
PIK3C2A               0.002   phosphoinositide-3-kinase, class 2 alpha polypeptid...
XPO4                  0.001   exportin 4 
CCDC135               0.001   coiled-coil domain containing 135 
FASTKD1               0.001   FAST kinase domains 1 
PI4KA                 0.001   phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...
PI4KA                 0.001   phosphatidylinositol 4-kinase type 3 alpha isoform ...
CENPI                 0.001   centromere protein I 
LOC100293141          0.001   PREDICTED: similar to phosphatidylinositol 4-kinase...
TMC3                  0.001   transmembrane channel-like 3 
DZIP1L                0.001   DAZ interacting protein 1-like 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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