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Search of human proteins with 34335253
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34335253 disks large-associated protein 4 isoform a [Homo
sapiens]
(989 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34335253 disks large-associated protein 4 isoform a [Homo sap... 1998 0.0
gi|34335251 disks large-associated protein 4 isoform b [Homo sap... 813 0.0
gi|19923274 discs large homolog-associated protein 1 isoform alp... 799 0.0
gi|38202224 discs large-associated protein 2 [Homo sapiens] 677 0.0
gi|109891938 disks large-associated protein 4 isoform c [Homo sa... 577 e-164
gi|51339031 discs large homolog-associated protein 1 isoform bet... 556 e-158
gi|122937233 discs, large (Drosophila) homolog-associated protei... 500 e-141
gi|226371669 discs large homolog 7 isoform b [Homo sapiens] 83 1e-15
gi|226371667 discs large homolog 7 isoform a [Homo sapiens] 83 1e-15
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 54 7e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 54 9e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 51 6e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 49 2e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 48 4e-05
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 47 1e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 46 2e-04
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 45 3e-04
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 45 3e-04
gi|146134388 YLP motif containing 1 [Homo sapiens] 45 3e-04
gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho... 45 4e-04
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 45 4e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 44 6e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 44 6e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 43 0.001
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 43 0.002
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 43 0.002
gi|161016767 mucin 21 [Homo sapiens] 43 0.002
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 42 0.003
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 42 0.004
gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens] 42 0.004
>gi|34335253 disks large-associated protein 4 isoform a [Homo
sapiens]
Length = 989
Score = 1998 bits (5177), Expect = 0.0
Identities = 989/989 (100%), Positives = 989/989 (100%)
Query: 1 MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPL 60
MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPL
Sbjct: 1 MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPL 60
Query: 61 NNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFS 120
NNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFS
Sbjct: 61 NNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFS 120
Query: 121 TLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGSKKGGMEDGKGR 180
TLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGSKKGGMEDGKGR
Sbjct: 121 TLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGSKKGGMEDGKGR 180
Query: 181 RAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERSQPR 240
RAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERSQPR
Sbjct: 181 RAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERSQPR 240
Query: 241 YFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLS 300
YFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLS
Sbjct: 241 YFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLS 300
Query: 301 HAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIP 360
HAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIP
Sbjct: 301 HAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIP 360
Query: 361 CRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLD 420
CRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLD
Sbjct: 361 CRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLD 420
Query: 421 SVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYE 480
SVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYE
Sbjct: 421 SVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYE 480
Query: 481 AACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTG 540
AACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTG
Sbjct: 481 AACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTG 540
Query: 541 SLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVT 600
SLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVT
Sbjct: 541 SLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVT 600
Query: 601 SQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAP 660
SQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAP
Sbjct: 601 SQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAP 660
Query: 661 KRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDAND 720
KRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDAND
Sbjct: 661 KRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDAND 720
Query: 721 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPW 780
SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPW
Sbjct: 721 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPW 780
Query: 781 LETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVL 840
LETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVL
Sbjct: 781 LETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVL 840
Query: 841 SAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELY 900
SAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELY
Sbjct: 841 SAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELY 900
Query: 901 HLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAA 960
HLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAA
Sbjct: 901 HLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAA 960
Query: 961 KRAASVRQNSATESADSIEIYVPEAQTRL 989
KRAASVRQNSATESADSIEIYVPEAQTRL
Sbjct: 961 KRAASVRQNSATESADSIEIYVPEAQTRL 989
>gi|34335251 disks large-associated protein 4 isoform b [Homo
sapiens]
Length = 453
Score = 813 bits (2099), Expect = 0.0
Identities = 416/444 (93%), Positives = 420/444 (94%), Gaps = 7/444 (1%)
Query: 551 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 610
SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD
Sbjct: 12 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71
Query: 611 SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ 670
SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ
Sbjct: 72 SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ 131
Query: 671 ERTRRNGSHLSEDNGP----KAIDVMAPSS-ESSVPSHSMSSRRDTDSDTQDANDSSCKS 725
+ E+ P ++I V SSVPSHSMSSRRDTDSDTQDANDSSCKS
Sbjct: 132 VDCIQPVP--KEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189
Query: 726 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 785
SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS
Sbjct: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249
Query: 786 SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS 845
SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS
Sbjct: 250 SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS 309
Query: 846 AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN 905
AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN
Sbjct: 310 AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN 369
Query: 906 SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS 965
SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS
Sbjct: 370 SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS 429
Query: 966 VRQNSATESADSIEIYVPEAQTRL 989
VRQNSATESADSIEIYVPEAQTRL
Sbjct: 430 VRQNSATESADSIEIYVPEAQTRL 453
>gi|19923274 discs large homolog-associated protein 1 isoform alpha
[Homo sapiens]
Length = 977
Score = 799 bits (2063), Expect = 0.0
Identities = 476/1033 (46%), Positives = 623/1033 (60%), Gaps = 100/1033 (9%)
Query: 1 MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAF-AREARFPGQNTLPGDGLFP 59
MKGL SR H + D + L +DR PYLLSP E A + +N+ + + P
Sbjct: 1 MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGP 60
Query: 60 LNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGF 119
++ P SSTFPR HY S E+ +E ATK NR+PANLLDQFE+QLP+ RDG+
Sbjct: 61 FSD--PLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGY 118
Query: 120 STLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTA-GKV-GGNGSKKGGMEDG 177
TLQ+ R + R +SPGRIRHLVHSVQ+LF TK+ SLEG + G V GG S
Sbjct: 119 HTLQYKRTAVEHRSDSPGRIRHLVHSVQKLF-TKSHSLEGPSKGSVNGGKASPDEAQAAR 177
Query: 178 KGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERS 237
G+R+KSKER EPK R S GWWSSDDNLDG+ + + SG+MT+GR +RS
Sbjct: 178 YGKRSKSKERR--AEPKARP-STSPGWWSSDDNLDGDMCIYHAP---SGVMTMGRCPDRS 231
Query: 238 QPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWS-T 296
+YF+ AYNTIS +K +++N +TC +L V DT +K+ +WS T
Sbjct: 232 ASQYFLEAYNTISEQAVKASRSNND---------VKCSTCANLPVSLDTPLLKKSAWSST 282
Query: 297 LTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAE 356
LT+S A EV QK S +D++++KS+SC Q + YLQVP EW T +PR D
Sbjct: 283 LTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQVPQD--EW--TGYTPRGKD---- 334
Query: 357 GPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGE-------- 408
IPCRRMRSGSYIKAMGDEDS +S SPKPSPK AARR+SYL+ATQ SL E
Sbjct: 335 DEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISN 394
Query: 409 QSNPR------------------RSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCI 450
+ +P+ RSLD LD +L K S E Y +++
Sbjct: 395 EHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTIS----- 449
Query: 451 SQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRS 510
QV E E++ Q+E+ CES SE ES A E LDLP+P FR RS
Sbjct: 450 ------------------QVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRS 491
Query: 511 HSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTS 570
HSY+RAI+ GCSQ+++ VSL+S SPP +T ++ ++ SSC+ YKKTPPPVPPRTT+
Sbjct: 492 HSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTT 551
Query: 571 KPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVA--- 627
KPFIS+T QSSTESAQD Y+D Q + ++ SQSGLSNS++SLDS + A
Sbjct: 552 KPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIH 611
Query: 628 -PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGP 686
PA + + T+T+ + + K + SIGIQ E+ P
Sbjct: 612 GPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAP 671
Query: 687 KAIDVMAPSSESS------VPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSI 740
+ E S+S+++ D D D ++S +S E + P P +
Sbjct: 672 SKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIE---DNSCPGPMAR 728
Query: 741 SIDAGPRQAPKIAQIKRNLSYG----DNSDPALEASSLPPPDPWLETSSSSPAEPAQPGA 796
+ Q N + D+ D + S LPPPDPW+++ + P E Q
Sbjct: 729 QFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSV 788
Query: 797 CRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQ 856
C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++LGK+ +AVGSAQLLM+QKF Q
Sbjct: 789 CHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQ 848
Query: 857 FRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKR 916
FR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKFDEL+ LKAN+W+ ++ +K+
Sbjct: 849 FRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKK 908
Query: 917 KEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESAD 976
E++ PPPVPKKPAK + R+++ ++S QRQEARKRL+AAKRAASVRQNSATESA+
Sbjct: 909 --ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKRLMAAKRAASVRQNSATESAE 964
Query: 977 SIEIYVPEAQTRL 989
SIEIY+PEAQTRL
Sbjct: 965 SIEIYIPEAQTRL 977
>gi|38202224 discs large-associated protein 2 [Homo sapiens]
Length = 975
Score = 677 bits (1747), Expect = 0.0
Identities = 452/1053 (42%), Positives = 591/1053 (56%), Gaps = 142/1053 (13%)
Query: 1 MKGLGDSRPRHLSDS-----LDPPH--EPLFAGTD-RNPYLLSPTEAF--AREARFPGQN 50
MKGL SR + S L PP E L G D R PYLLSP ++ R P +
Sbjct: 1 MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPRSS 60
Query: 51 TLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEK 110
+ P+ SSTFPR+HY+SH++ ++ +HA A KINR+PANLLDQFEK
Sbjct: 61 VHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAV-AHAGA-KINRIPANLLDQFEK 118
Query: 111 QLPIHRDGFSTLQFPRGEAKA--RGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNG 168
QLP+HRDGF TLQ+ R A A R ESPGRIRHLVHSVQ+LF TK+ SLEG++ K NG
Sbjct: 119 QLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLF-TKSHSLEGSS-KSNANG 176
Query: 169 SKKGGMEDGK--------GRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRS 220
+K G D +R+KSKER G+P R +S WWSSDDNLD ++ +R+
Sbjct: 177 TKADGRADDHHHAHHAKHSKRSKSKERKPEGKP----RPGMSSWWSSDDNLDSDS-TYRT 231
Query: 221 SGPASGLMTLGRQAERSQPRYFMHAYNTISGHM-LKTTKNNTTELTAPPPPPAPPATCPS 279
L R + A + G + LKT+K+N + C
Sbjct: 232 PS------VLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNND---------VKCSACEG 276
Query: 280 LGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGG 339
L + D Y+KR SWSTLT+S A E +K+S LDK LL + HYLQVP
Sbjct: 277 LALTPDAKYLKRSSWSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQD-- 334
Query: 340 EWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYL 399
EW ++ + IPCRRMRSGSYIKAMGDE+S ES SPK SPK+A + L
Sbjct: 335 EWGGYPTGGKDEE------IPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILPEPLL 388
Query: 400 RAT-QQSLGE---QSNPRRSLD-----RLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCI 450
++ Q+ LGE Q+ + + D LD K S + Y +L+ +SC+
Sbjct: 389 KSIGQRPLGEHQTQTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCV 448
Query: 451 SQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRS 510
SQ V EAE++ Q+E+ CES SE ES A + LDLP FR+RS
Sbjct: 449 SQ-----------------VSEAEINGQFESVCESVFSEVESQAMDALDLP--GCFRTRS 489
Query: 511 HSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTS 570
HSYLRAIQAG SQ+++ + + ++P T ++ ++ + ++ YKKTPPPVPPRTTS
Sbjct: 490 HSYLRAIQAGYSQDDECIPM--MTPSDITSTIRSTAAVSYTN----YKKTPPPVPPRTTS 543
Query: 571 KPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS--GLSNSSDSLDSSTRP---------- 618
KP ISVT QSSTES QD Y DS+ + Q GL NS+DSLDS+
Sbjct: 544 KPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQ 603
Query: 619 ---PSVTRGGVAPAPEAPEPPPKHAALKSEQGTL-------------------TSSESHP 656
P V + +A LKS ++ T+++S
Sbjct: 604 RHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIGIQDSEFPEHQPYPRSDVETATDSDT 663
Query: 657 EAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQ 716
E+ R+ S+G+Q + N A V A P H T+
Sbjct: 664 ESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAA-VQADLELEGFPGHIT---------TE 713
Query: 717 DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 776
D S +R TP S A + + + SY ++ ++ S+LPP
Sbjct: 714 DKGLQFGSSFQRHSEPSTPTQYS---------AVRTVRTQGLFSYREDYRTQVDTSTLPP 764
Query: 777 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 836
PDPWLE + + E + CRRDG WFLKLL AET+R+EGWC +M++E +EN+LSEE+L
Sbjct: 765 PDPWLEPAIDT-VETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEIL 823
Query: 837 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 896
GK+ SAVGSAQLLMSQKFQQF LC+QN++P A PRPT+QDLAG+WD+LQLSIED+SMKF
Sbjct: 824 GKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKF 883
Query: 897 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 956
DEL L+ N W+++E+PE RKEE+K PPP+PKKP K K ++R+K+ D D+QRQEAR+R
Sbjct: 884 DELQRLRLNDWKMMESPE-RKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRR 942
Query: 957 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 989
L+AAKRAAS RQNSA+E ADSIEIY+PEAQTRL
Sbjct: 943 LMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975
>gi|109891938 disks large-associated protein 4 isoform c [Homo
sapiens]
Length = 285
Score = 577 bits (1486), Expect = e-164
Identities = 285/285 (100%), Positives = 285/285 (100%)
Query: 705 MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN 764
MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN
Sbjct: 1 MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN 60
Query: 765 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK 824
SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK
Sbjct: 61 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK 120
Query: 825 ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL 884
ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL
Sbjct: 121 ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL 180
Query: 885 LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD 944
LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD
Sbjct: 181 LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD 240
Query: 945 ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 989
ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL
Sbjct: 241 ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 285
>gi|51339031 discs large homolog-associated protein 1 isoform beta
[Homo sapiens]
Length = 675
Score = 556 bits (1433), Expect = e-158
Identities = 316/679 (46%), Positives = 414/679 (60%), Gaps = 70/679 (10%)
Query: 351 TDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGE-- 408
T + IPCRRMRSGSYIKAMGDEDS +S SPKPSPK AARR+SYL+ATQ SL E
Sbjct: 27 TPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELT 86
Query: 409 ------QSNPR------------------RSLDRLDSVDMLLPSKCPSWEEDYTPVSDSL 444
+ +P+ RSLD LD +L K S E Y ++
Sbjct: 87 TLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTI 146
Query: 445 NDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPS 504
+ QV E E++ Q+E+ CES SE ES A E LDLP+P
Sbjct: 147 S-----------------------QVSEMEVNGQFESVCESVFSELESQAVEALDLPMPG 183
Query: 505 YFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPV 564
FR RSHSY+RAI+ GCSQ+++ VSL+S SPP +T ++ ++ SSC+ YKKTPPPV
Sbjct: 184 CFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPV 243
Query: 565 PPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRG 624
PPRTT+KPFIS+T QSSTESAQD Y+D Q + ++ SQSGLSNS++SLDS +
Sbjct: 244 PPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEA 303
Query: 625 GVA----PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHL 680
A PA + + T+T+ + + K + SIGIQ
Sbjct: 304 ANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKT 363
Query: 681 SEDNGPKAIDVMAPSSESS------VPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCT 734
E+ P + E S+S+++ D D D ++S +S E +
Sbjct: 364 GENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIE---DNSC 420
Query: 735 PHPNSISIDAGPRQAPKIAQIKRNLSYG----DNSDPALEASSLPPPDPWLETSSSSPAE 790
P P + + Q N + D+ D + S LPPPDPW+++ + P E
Sbjct: 421 PGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLE 480
Query: 791 PAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLM 850
Q C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++LGK+ +AVGSAQLLM
Sbjct: 481 AVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLM 540
Query: 851 SQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLV 910
+QKF QFR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKFDEL+ LKAN+W+ +
Sbjct: 541 AQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQM 600
Query: 911 ETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNS 970
+ +K+ E++ PPPVPKKPAK + R+++ ++S QRQEARKRL+AAKRAASVRQNS
Sbjct: 601 DPLDKK--ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKRLMAAKRAASVRQNS 656
Query: 971 ATESADSIEIYVPEAQTRL 989
ATESA+SIEIY+PEAQTRL
Sbjct: 657 ATESAESIEIYIPEAQTRL 675
>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
[Homo sapiens]
Length = 979
Score = 500 bits (1288), Expect = e-141
Identities = 380/1074 (35%), Positives = 500/1074 (46%), Gaps = 237/1074 (22%)
Query: 29 RNPYLLSPTEAFAREARF-------------------PGQNTLPGDGLFPLNNQLPPPSS 69
R PYLL EAF+ E RF G + P G P + SS
Sbjct: 30 RAPYLLGSREAFSTEPRFCAPRAGLGHISPEGPLSLSEGPSVGPEGG--PAGAGVGGGSS 87
Query: 70 TFPRIHYNSHFEVPEESPFPS------HAQATKINRLPANLLDQFEKQLPIHRDGFSTLQ 123
TFPR++ P + PF + H Q RLP LLDQFEKQLP+ +DGF TL
Sbjct: 88 TFPRMY-------PGQGPFDTCEDCVGHPQGKGAPRLPPTLLDQFEKQLPVQQDGFHTLP 140
Query: 124 FPRGEAKA--------------RGESPGRIRHLVHSVQRLFFTK------------APSL 157
+ RG A A R ESP RIRHLVHSVQ+LF P
Sbjct: 141 YQRGPAGAGPGPAPGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKA 200
Query: 158 EGTAGKVGGN--GSKKGGM---------------EDGKGRRAKSKERAKAGEPKRRSRSN 200
EG G G + G GG + G+R+KSK+R G + +S
Sbjct: 201 EGRGGSGGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKGDGRHQAKS--- 257
Query: 201 ISGWWSSDDNLDGEAGAF---RSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKTT 257
+GWWSSDDNLD ++G R G G L + F G L
Sbjct: 258 -TGWWSSDDNLDSDSGFLAGGRPPGEPGGPFCLEGPDGSYRDLSFKGRSGGSEGRCL--- 313
Query: 258 KNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSL 317
C + + D VKR +W T+ +S + A K L
Sbjct: 314 ------------------ACTGMSMSLDGQSVKRSAWHTMMVSQGRD--GYPGAGPGKGL 353
Query: 318 LKSKSCHQGLAYHYLQVPGGG-GEWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDE 376
L ++ + YHYLQVP G + T +G IPCRRMRSGSYIKAMGDE
Sbjct: 354 LGPETKAKARTYHYLQVPQDDWGGYPT---------GGKDGEIPCRRMRSGSYIKAMGDE 404
Query: 377 DSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEED 436
+S +S GSPK SPK ARR + R++
Sbjct: 405 ESGDSDGSPKTSPKAVARRFTTRRSSSV-------------------------------- 432
Query: 437 YTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSD----QYEAACESACSEAES 492
D + C+ S IP G+ + + +LSD Q EA C S E ES
Sbjct: 433 -----DQARINCCVPPRIHPRSSIP---GYSRSLTTGQLSDELNQQLEAVCGSVFGELES 484
Query: 493 TAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSS 552
A + LDLP FR RSHSYLRAIQAGCSQ++D + L + +P +G P SS
Sbjct: 485 QAVDALDLP--GCFRMRSHSYLRAIQAGCSQDDDCLPLLA-TPAAVSGR-------PGSS 534
Query: 553 CLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSL 612
++K PPP+PP + + P IS+T QSST+SA +++ T+ G + S
Sbjct: 535 --FNFRKAPPPIPPGSQAPPRISITAQSSTDSAHESF----------TAAEGPARRCSSA 582
Query: 613 DSSTRPPSVTRG-GVAPAPEAPEPPPKHAALKSEQG--------------------TLTS 651
D P R +AP P P P +K+ G T
Sbjct: 583 DGLDGPAMGARTLELAPVPPRASPKPPTLIIKTIPGREELRSLARQRKWRPSIGVQVETI 642
Query: 652 SESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDT 711
S+S E +R+ SIG+Q + + N A V A + + +
Sbjct: 643 SDSDTENRSRREFHSIGVQVEEDKRRARFKRSNSVTA-GVQADLELEGLAGLATVA---- 697
Query: 712 DSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN-----SD 766
T+D +S +R + P P + + + + +Y +
Sbjct: 698 ---TEDKALQFGRSFQRHASEPQPGPRAPTYSVF-----RTVHTQGQWAYREGYPLPYEP 749
Query: 767 PALEASSLPPPDP-----------WLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERL 815
PA + S P P P W+E S S + + C RDG WF+K+L+AE E+L
Sbjct: 750 PATDGSPGPAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEKL 809
Query: 816 EGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTA 875
E WC QM++E ++ L EE+L K+ SAVGS QLL+SQK QQF LC+Q+++P A P PT
Sbjct: 810 EHWCQQMEREAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPTF 869
Query: 876 QDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKP 935
QDLAGFWDLLQLSIED+++KF EL LKANSW+L+E KEEKK PPP+PKKP + +
Sbjct: 870 QDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKLLEP----KEEKKVPPPIPKKPLRGRG 925
Query: 936 AVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 989
++++ D+ D+QRQEARKRLLAAKRAAS R +SATESADSIEIY+PEAQTRL
Sbjct: 926 VPVKERSLDSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979
>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
Length = 842
Score = 83.2 bits (204), Expect = 1e-15
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%)
Query: 803 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 862
+F +LQ+ETE+L C + D++ E ++ ++ + +AVG +LLM ++F+QF GL +
Sbjct: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490
Query: 863 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 922
T DL GFWD++ IED+ KF+ L L+ + WQ+ +
Sbjct: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548
Query: 923 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 978
V +K S A S+ K DA R AR RL A K A +RQ E+A S+
Sbjct: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599
>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
Length = 846
Score = 83.2 bits (204), Expect = 1e-15
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%)
Query: 803 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 862
+F +LQ+ETE+L C + D++ E ++ ++ + +AVG +LLM ++F+QF GL +
Sbjct: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490
Query: 863 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 922
T DL GFWD++ IED+ KF+ L L+ + WQ+ +
Sbjct: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548
Query: 923 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 978
V +K S A S+ K DA R AR RL A K A +RQ E+A S+
Sbjct: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 53.9 bits (128), Expect = 7e-07
Identities = 69/282 (24%), Positives = 107/282 (37%), Gaps = 23/282 (8%)
Query: 520 GCSQEEDSVSLQSL-SPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTV 578
G ++ SL SL S PP+ GS P ++ ++ P + + P
Sbjct: 2488 GAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNP------ 2541
Query: 579 QSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPK 638
S + AQ +++ +S +S SG S+SS S SS G +
Sbjct: 2542 -KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
Query: 639 HAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSES 698
+ + S + +S S ++ SS + + S S + + + SS S
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
Query: 699 SVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRN 758
S S S SS TD D SSC S + + P T P++ + A P +A K A R
Sbjct: 2661 SSSSSSSSSSSTTDED------SSCSSDDEAAPAPTAGPSAQA--ALPTKATKQAGKARP 2712
Query: 759 LSYGDNSDPALEASSLPPPDPWLETSSSSPAEP-AQPGACRR 799
++ PPP P + P +P AQ GA R
Sbjct: 2713 SAHSPGKKTPAPQPQAPPPQP------TQPLQPKAQAGAKSR 2748
Score = 37.4 bits (85), Expect = 0.070
Identities = 65/270 (24%), Positives = 98/270 (36%), Gaps = 53/270 (19%)
Query: 383 GSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSD 442
GS P+ ++ + + +AT L ++ P + + DS + P K + E+D S+
Sbjct: 2502 GSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFE--DSGNPKSPDKAQA-EQDGAEESE 2558
Query: 443 SLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESA---CSEAESTAAE--- 496
S + SS S +S G E + E E + C + CS A S AA
Sbjct: 2559 SSSSSSSGSSSSSSSS---SSSGSETEGEE-EGDKNGDGGCGTGGRNCSAASSRAASPAS 2614
Query: 497 --------TLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTL 548
+ S S S S + + S S S S S S+ S S+S T
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674
Query: 549 PSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNS 608
SSC + P P T S ++A T + T Q+G
Sbjct: 2675 EDSSCSSDDEAAPAP-------------TAGPSAQAALPT---------KATKQAG---- 2708
Query: 609 SDSLDSSTRPPSVTRGGVAPAPEAPEPPPK 638
RP + + G PAP+ PPP+
Sbjct: 2709 ------KARPSAHSPGKKTPAPQPQAPPPQ 2732
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 53.5 bits (127), Expect = 9e-07
Identities = 94/436 (21%), Positives = 161/436 (36%), Gaps = 33/436 (7%)
Query: 366 SGSYIKAMGDEDSD--------ESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLD 417
+GS K D+DSD +S G+ + S + S + S+ S D
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562
Query: 418 RLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSD 477
DS D S + D + SDS + S S +S ++ SD
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSD-SDSSDSSDSDSSDSSNSS---DSSDSSDSSDSSDSSD 618
Query: 478 QYEAACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPP 537
++ +S+ SE++S+ +++ S S + + + S DS S
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 538 STGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKS 597
S+ SNS SS S S++S+ DS D +
Sbjct: 679 SSSDSSNSSDSSDSS------------------DSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 598 EVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTS--SESH 655
+S S SNSSDS DSS S + + ++ + + S + +S S+S
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 656 PEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSM-SSRRDTDSD 714
+ +S + + + S S D+ + + SS SS S+S SS SD
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 715 TQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSL 774
+ D++DSS S S +S S D+ + + + NS + ++S+
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900
Query: 775 PPPDPWLETSSSSPAE 790
D ++SS ++
Sbjct: 901 SDSDSSDSSNSSDSSD 916
Score = 52.0 bits (123), Expect = 3e-06
Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 35/424 (8%)
Query: 375 DEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPS-KCPSW 433
+ DS +S S S + + S S + SN S D DS + S S
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSS----DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 434 EEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAEST 493
+ D + SDS N +S S + ++ S + +S+ S S
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSS--------------DSSDSSNSSDSSDSSDSSNSSD 754
Query: 494 AAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSC 553
++++ D S S S + + S DS + S ++ SNS SS
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS- 813
Query: 554 LVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHK-SEVTSQSGLSNSSDSL 612
+ ++ S + SS S DS D S+ +++S SNSSDS
Sbjct: 814 -----DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Query: 613 DSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQER 672
DSS S + + E+ + S + S + +++ S
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 673 TRRNGSHLSEDNGPKAIDV--MAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSL 730
+ N + N + D + SS+SS S S +S +DS++ D++DSS S
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988
Query: 731 PDCTPHPNSI-------SIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 783
D + +S S D+ + N S NS + ++S ++
Sbjct: 989 SDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS 1048
Query: 784 SSSS 787
S SS
Sbjct: 1049 SDSS 1052
Score = 51.2 bits (121), Expect = 5e-06
Identities = 85/388 (21%), Positives = 140/388 (36%), Gaps = 19/388 (4%)
Query: 366 SGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDML 425
S S + + SD S S S ++ S + E SN + + DS +
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN-- 940
Query: 426 LPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACES 485
S S D + SDS N S + S ++ SD +++ +S
Sbjct: 941 --SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS-DS 997
Query: 486 ACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNS 545
+ S S ++++ D S S+S + + S DS S + SNS
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 546 RTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHK-----SEVT 600
SS + +S+ S +S++S+ + DS D S+ +
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS--DSSDSSDSSDSSDSS 1115
Query: 601 SQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAP 660
S SNSSDS DSS S + + ++ E + S + +S S +
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 661 KRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTD-------S 713
SS + S S+ + + SS+SS S S S +D S
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235
Query: 714 DTQDANDSSCKSSERSLPDCTPHPNSIS 741
D+ D++DSS S+ D + +S S
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263
Score = 48.1 bits (113), Expect = 4e-05
Identities = 90/440 (20%), Positives = 161/440 (36%), Gaps = 12/440 (2%)
Query: 366 SGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDML 425
S S + SD S S ++ S + + + S+ S D DS D
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848
Query: 426 LPSKCPSWEEDYTPVSDSLNDS-SCISQIFGQASLIPQLFGHEQQVREAELSDQYEAA-C 483
S + D + SDS N S S S +S + ++ SD ++
Sbjct: 849 DGS-----DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903
Query: 484 ESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLS 543
+S+ S S ++++ + S + S + + + S DS + S ++ S
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 544 NSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQD--HKSEVTS 601
NS S+ + + ++ S + SS S DS D + S+ ++
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023
Query: 602 QSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK 661
S SNSSDS DSS S + + ++ + S + +S S + +
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 662 RKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTD-SDTQDAND 720
SS + S S+ + + SS+SS S S S +D SD+ +++D
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 721 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPW 780
SS S D + +S S D+ + N S +S + ++S
Sbjct: 1144 SSDSSESSDSSDSS--DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201
Query: 781 LETSSSSPAEPAQPGACRRD 800
++S SS + + + D
Sbjct: 1202 SDSSDSSDSSDSSDSSDSSD 1221
Score = 45.1 bits (105), Expect = 3e-04
Identities = 74/350 (21%), Positives = 119/350 (34%), Gaps = 12/350 (3%)
Query: 378 SDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDY 437
SD S S ++ ++ S S+ S D DS + S S D
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS-DSSDSSDSSDS 994
Query: 438 TPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAET 497
+ SDS N S S ++ S + +S+ S S ++++
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDS---------SNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045
Query: 498 LDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAY 557
D S + S S + + S DS S + SNS SS
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105
Query: 558 KKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTR 617
+ +S S S++S+ + + S+ + S S+SSDS DSS
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165
Query: 618 PPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNG 677
S + + + + + S + +S S + SS +
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225
Query: 678 SHLSEDNGPKAIDVMAPSSESSVPSHS--MSSRRDTDSDTQDANDSSCKS 725
S S+ N + SS+SS S S S D+ SD+ D +DS KS
Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275
Score = 37.4 bits (85), Expect = 0.070
Identities = 70/345 (20%), Positives = 117/345 (33%), Gaps = 6/345 (1%)
Query: 366 SGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDML 425
S S + + SD + S ++ S + + SN S D DS D
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016
Query: 426 LPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACES 485
S + D + SDS + S S + ++ S + +S
Sbjct: 1017 NSSDSSN-SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 486 ACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSV----SLQSLSPPPSTGS 541
+ S S ++++ D S S S + + S DS S S S+ S
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135
Query: 542 LSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTS 601
+S + SS + + ++ S + SS S DS D S+ +
Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD-SSDSSD 1194
Query: 602 QSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK 661
S S+SSDS DSS S + + ++ + + + S + +S S+ +
Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254
Query: 662 RKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMS 706
SS + + S NG SE S +HS S
Sbjct: 1255 SSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
Score = 33.9 bits (76), Expect = 0.78
Identities = 43/200 (21%), Positives = 75/200 (37%), Gaps = 17/200 (8%)
Query: 575 SVTVQSSTESAQDTY-LDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAP 633
S T S D+Y D + + + + S SN +D +S + S +RG
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGD-------- 490
Query: 634 EPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMA 693
A+ S++ + S + A S + NG+ + ++ D
Sbjct: 491 ------ASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544
Query: 694 PSSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIA 753
S+SS S SS SD+ D++ S SS S D + +S S D+ + +
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS--DSSDSDSSDSSDSDSSDSSNSS 602
Query: 754 QIKRNLSYGDNSDPALEASS 773
+ D+SD + + S
Sbjct: 603 DSSDSSDSSDSSDSSDSSDS 622
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 50.8 bits (120), Expect = 6e-06
Identities = 113/501 (22%), Positives = 165/501 (32%), Gaps = 99/501 (19%)
Query: 346 LSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQS 405
+ P + P+ RR S S + S S PK PK R S R T++
Sbjct: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPK---RTSSPPRKTRRL 388
Query: 406 LGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQAS-LIPQLF 464
S PRR S P P TP + S +S G+ S + +
Sbjct: 389 SPSASPPRRR--HRPSPPATPP---PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHK 443
Query: 465 GHEQ--------QVREAELSD-------------------QYEAACESACSEAESTAAET 497
G E+ + R+ ELS+ QY + + S++ S+++
Sbjct: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503
Query: 498 LDLPLPSYF------RSRSHSYLRAIQAGCSQEEDSVS-----LQSLSPPPSTGSLSNSR 546
+ P S+ R R HS R+ + + S +S SPPP + R
Sbjct: 504 DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPP-----TRRR 558
Query: 547 TLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLS 606
PS + ++TP P P R T P + S S
Sbjct: 559 RSPSPAPPPRRRRTPTPPPRRRTPSP---------------------PPRRRSPSPRRYS 597
Query: 607 NSSDSLDSSTRPPSVTRGGVAPAPE----APEPPPKHAALKSEQGTLTSSESHP---EAA 659
PP R +P P+ +P PPPK A S S S P ++
Sbjct: 598 -----------PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSS 646
Query: 660 PKRKLSSIGIQERTRRNGS---HLSEDNGPKAIDVMAPSSESSVPSHSMSS---RRDTDS 713
P K S + + R+ S E P+ +PS P S S RR S
Sbjct: 647 PVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS 706
Query: 714 DTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASS 773
Q S + TP P I A P + ++ + S + +PA +
Sbjct: 707 SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP-SPQSVRRVSSSRSVSGSPEPAAKKPP 765
Query: 774 LPPPDPWLETSSSSPAEPAQP 794
PP P S S+ PA P
Sbjct: 766 -APPSPVQSQSPSTNWSPAVP 785
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 49.3 bits (116), Expect = 2e-05
Identities = 80/312 (25%), Positives = 108/312 (34%), Gaps = 71/312 (22%)
Query: 501 PLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKT 560
P+PS F +S R + A + S SL S + +T S + + S
Sbjct: 2450 PVPSAFSDQS----RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA------- 2498
Query: 561 PPPVPPRTTSKPFISVTVQSSTESAQ----DTYLDSQDHKSEVTSQSGLSNSSDSLDSST 616
P VP +P S Q + A S S +S S S+SS S SS
Sbjct: 2499 -PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSG 2557
Query: 617 RPPSVTRGGVAPA-PE-------APEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIG 668
S + G P PE +P P PK A + PE P +
Sbjct: 2558 SSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP---------PEPTPAK------ 2602
Query: 669 IQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKSSER 728
R RR+ S S SS SS S S SS + S + ++ SS SS
Sbjct: 2603 ---RKRRSSSSSSS------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 729 SLPDCTPHPNSISIDAGPRQAP-------------KIAQIKRNLSYGDNSDPALEASSLP 775
S P P ++ A P++ P + R+LSY P P
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY----SPVERRRPSP 2703
Query: 776 PPDPWLETSSSS 787
P P + SSSS
Sbjct: 2704 QPSPRDQQSSSS 2715
Score = 46.2 bits (108), Expect = 2e-04
Identities = 62/240 (25%), Positives = 94/240 (39%), Gaps = 38/240 (15%)
Query: 503 PSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCL-------- 554
P+ ++ S L A+Q + S S S S S+ S S+S + SS
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 555 ----VAYKKTPPPVP-----------PRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEV 599
VA K+ P P P P T + SS+ S+ + S S
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 600 TSQSGLSNSSDSLDSSTRPPSVTRGG--VAPAPEAP-EPPPKHAALKSEQ---GTLTSSE 653
+S S S+SS S SS+ PS + G P P +P +PPP +S + +L S
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
Query: 654 SHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDS 713
S + +R+ S + + R+ S + G + +S PSH RR+T S
Sbjct: 2690 SLSYSPVERRRPS---PQPSPRDQQSSSSERGSR----RGQRGDSRSPSH--KRRRETPS 2740
Score = 41.6 bits (96), Expect = 0.004
Identities = 72/300 (24%), Positives = 106/300 (35%), Gaps = 65/300 (21%)
Query: 518 QAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVT 577
++G SQE D + P S S S + P S A +TP R+ S P +
Sbjct: 1538 RSGSSQELD------VKPSASPQERSESDSSPDSK---AKTRTPLRQRSRSGSSPEV--- 1585
Query: 578 VQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPP 637
D KS ++ + S SS + R + G +PE P P
Sbjct: 1586 ----------------DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAP 1629
Query: 638 KHAALKSEQGT-----------LTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGP 686
+ +S G+ +S+ES PE PK RT R GS S +
Sbjct: 1630 RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK---------SRTARRGSRSSPE--- 1677
Query: 687 KAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDC---TP--HPNSIS 741
P ++S P SSR + T+ A S S S P+ TP H S S
Sbjct: 1678 -------PKTKSRTPPRRRSSRSSPEL-TRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729
Query: 742 IDA-GPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 800
+ + P + + ++ +R+ S + S P L+ S S RRD
Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
Score = 39.7 bits (91), Expect = 0.014
Identities = 62/264 (23%), Positives = 96/264 (36%), Gaps = 38/264 (14%)
Query: 507 RSRSHSYL--RAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPV 564
R RSHS R ++G S E + S S S S ++ SS +++
Sbjct: 710 RGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISS------RRSRSLS 763
Query: 565 PPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRG 624
PR+ +K +S+ S S KS+ + S SS S PP +R
Sbjct: 764 SPRSKAKSRLSLRRSLSGSSP------CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS 817
Query: 625 GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDN 684
+ PPPK ++ S +SH ++P K+ S R GS S
Sbjct: 818 -------SSSPPPK------QKSKTPSRQSHSSSSPHPKVKS----GTPPRQGSITSPQA 860
Query: 685 GPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDA 744
+++ S S P + SR + ++ KSS TP S S +
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS-------TPPRQSPSRSS 913
Query: 745 GPRQAPKIAQIKRNLSYGDNSDPA 768
P+ K R S+ +S P+
Sbjct: 914 SPQPKVKAIISPRQRSHSGSSSPS 937
Score = 37.7 bits (86), Expect = 0.054
Identities = 55/247 (22%), Positives = 89/247 (36%), Gaps = 19/247 (7%)
Query: 572 PFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPE 631
P + + QS+ S + S D + S S SS LD+ R PS R A +PE
Sbjct: 1367 PSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426
Query: 632 APEPPPKHAALKSEQGTLTSSESHPEAAPKRKL--SSIGIQERTR---RNGSHLSEDNGP 686
+ P+ + +S G+ + L SS G+++ R R S P
Sbjct: 1427 MKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP 1486
Query: 687 KAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKS---SERSLPDCTPHPNSISID 743
KA+ S S ++++ T + ++SS + L + +S +D
Sbjct: 1487 KALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 744 AGPRQAPK-----------IAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPA 792
P +P+ A+ + L S + E S P S SSP
Sbjct: 1547 VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606
Query: 793 QPGACRR 799
+P A R
Sbjct: 1607 KPRAAPR 1613
Score = 37.4 bits (85), Expect = 0.070
Identities = 60/245 (24%), Positives = 90/245 (36%), Gaps = 54/245 (22%)
Query: 601 SQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAP 660
SQS +++ SS + ++ + PA + P P A S+Q +++ P A
Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAF--SDQSRCLIAQTTPVAG- 2471
Query: 661 KRKLSSIGIQERTRRNGSHLS-----------EDNG----------PKAIDVMAP----- 694
+ LSS + T G H D G P A+ + P
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERR 2531
Query: 695 SSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERS------------LPDCTPHPNSISI 742
SS SS S S SS + S + ++ SS SE S +P TP P
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
Query: 743 DAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAE------------ 790
+ P + P A+ KR S +S + +SS +SSSS +
Sbjct: 2592 EGRPPE-PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 791 PAQPG 795
PA+PG
Sbjct: 2651 PAKPG 2655
Score = 36.6 bits (83), Expect = 0.12
Identities = 98/428 (22%), Positives = 152/428 (35%), Gaps = 74/428 (17%)
Query: 340 EWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDE----SGGSP--KPSPKTAA 393
E S++ SP D P RR RSGS + SG SP K P+T +
Sbjct: 1417 ERSSSASSPEMKDGLPR--TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS 1474
Query: 394 RRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQI 453
R +S ++ + PR S + L +KC + + + + S++ +
Sbjct: 1475 RGRSECDSSPEPKALPQTPRPRSRSPSSPE--LNNKCLTPQRERSGSESSVDQKTVARTP 1532
Query: 454 FGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHSY 513
GQ S G Q++ D +A SE++S+ P RSRS S
Sbjct: 1533 LGQRSRS----GSSQEL------DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS 1582
Query: 514 L----------RAIQAGCSQEED--------SVSLQSLSPPPS------------TGSLS 543
R ++G S E + S SP P +GS S
Sbjct: 1583 PEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSS 1642
Query: 544 NSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS 603
R PS + + +P P T++ + + T+S S E+T ++
Sbjct: 1643 KGRG-PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA 1701
Query: 604 GLSNSSDSLDSS--TRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK 661
LS S S SS TR + R +P+ +PEP K + +S ++P+
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEK---------SRSSRRRRSASSPR 1752
Query: 662 RKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDS 721
K +S RR S PK + S S + RRD +Q +
Sbjct: 1753 TKTTS-------RRGRS-----PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
Query: 722 SCKSSERS 729
+S RS
Sbjct: 1801 RQRSRSRS 1808
Score = 35.8 bits (81), Expect = 0.20
Identities = 83/378 (21%), Positives = 132/378 (34%), Gaps = 40/378 (10%)
Query: 461 PQLFGHEQQVREAELSDQY---EAACESACSEAESTAAETLDLPLPSYFRSRSHSY---- 513
P L EQ R + S +A ++ S +S ++ LD + R RS S
Sbjct: 1367 PSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426
Query: 514 ----LRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNS----RTLPS------SSCLVAYKK 559
L + S+ S L+ S PS SLS S + +P S C + +
Sbjct: 1427 MKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP 1486
Query: 560 TPPPVPPRTTSKPFISVTVQSST------ESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD 613
P PR S+ S + + S ++ +D + Q S SS LD
Sbjct: 1487 KALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 614 --SSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQE 671
S P + +P +A P +S S+S R SS +++
Sbjct: 1547 VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606
Query: 672 RTR-----RNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKS- 725
+ R ++GS S + A + S S S + S T+ + + KS
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR 1666
Query: 726 ----SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWL 781
RS P+ + R +P++ + R ++ + E S PP
Sbjct: 1667 TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR 1726
Query: 782 ETSSSSPAEPAQPGACRR 799
S SSP EPA+ R
Sbjct: 1727 SPSVSSP-EPAEKSRSSR 1743
Score = 35.4 bits (80), Expect = 0.27
Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 7/163 (4%)
Query: 523 QEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSST 582
+++D + P PS S P+ + L+A + P P TT P V +
Sbjct: 338 KDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATT--PLSQEPVNPPS 395
Query: 583 ESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAAL 642
E A T S E Q S+SS+S S +P V+R + +PE+P+P P +
Sbjct: 396 E-ASPTRDRSPPKSPEKLPQ---SSSSESSPPSPQPTKVSR-HASSSPESPKPAPAPGSH 450
Query: 643 KSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNG 685
+ + TS A + K S R R+ S + G
Sbjct: 451 REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRG 493
Score = 33.5 bits (75), Expect = 1.0
Identities = 51/219 (23%), Positives = 81/219 (36%), Gaps = 42/219 (19%)
Query: 614 SSTRPPSVTRGGVAPAPEAPE-------------PPPKHAALKSEQGTLTSSESHPEAAP 660
SS P R PAPE P+ P PK K ++ SES
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208
Query: 661 KRKLSS----IGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPS-HSMSSRRDTDSDT 715
++K S E +R + + K+ D S S+ P+ S + R T +D+
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268
Query: 716 QDANDSS--------CKSSERSLPDCTPHPNSISIDAGPR-------------QAPKIAQ 754
++D+S K+ +L +P P S G +P+ A
Sbjct: 269 ASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT 328
Query: 755 IKRNLSYGD-NSDPALEASSLPPPDPWLETSSSSPAEPA 792
+ + Y D + D ++++ P P P E SS+ P PA
Sbjct: 329 KQPSSPYEDKDKDKKEKSATRPSPSP--ERSSTGPEPPA 365
Score = 31.6 bits (70), Expect = 3.8
Identities = 48/219 (21%), Positives = 79/219 (36%), Gaps = 22/219 (10%)
Query: 595 HKSEVTSQSGLSNSSDSLDSSTRPPSVTRG--GVAPAPEAPEPPPKHAALKSEQGTLTSS 652
H+S + S++S S S + T G +P+P + A T T
Sbjct: 261 HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320
Query: 653 ESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRR--- 709
S PE A K+ S +++ ++ S P+ + E P+ ++ R
Sbjct: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER---SSTGPEPPAPTPLLAERHGGS 377
Query: 710 -----DTDSDTQDANDSSCKSSERS-LPDCTPH--PNSISIDAGPRQAPKIAQIKRNLSY 761
T + N S S R P +P P S S ++ P +P+ ++ R+ S
Sbjct: 378 PQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSP-PSPQPTKVSRHASS 436
Query: 762 GDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 800
S P P E SSS ++ G +RD
Sbjct: 437 SPES-----PKPAPAPGSHREISSSPTSKNRSHGRAKRD 470
Score = 30.4 bits (67), Expect = 8.6
Identities = 54/233 (23%), Positives = 89/233 (38%), Gaps = 29/233 (12%)
Query: 508 SRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSS------SCLVAYKKTP 561
+RS +R A S + S S + PP+T + S SRT P + SC +P
Sbjct: 2069 TRSPPAIRRRSASGSSSDRSRS----ATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSP 2124
Query: 562 PPVP---------PRTTSKPFISVTVQSSTESAQDTYLDSQDHK------SEVTSQSGLS 606
P+ P +S+ +SV Q+ DH+ + S+ L+
Sbjct: 2125 TPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALA 2184
Query: 607 NSSDSLDSSTRPPSVTRGGVAP-APEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLS 665
++ SL ++ PPS++ G+A + P P P + + L S AA S
Sbjct: 2185 LTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLAS 2244
Query: 666 SIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDA 718
+ T N L++ P A M +S + + S + D + T A
Sbjct: 2245 ARTPAIPTAVN---LADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA 2294
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/241 (20%), Positives = 86/241 (35%), Gaps = 43/241 (17%)
Query: 597 SEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHP 656
++ + S SSD D + + GV P +A + PPK A S+ + +SSE P
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK-SSDSDSDSSSEDEP 179
Query: 657 EAAPKRKLSSIGIQERTR------------RNGSHLSEDNG------------------- 685
K K++ + ++ +T+ NG S +
Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239
Query: 686 -----PKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKS-----SERSLPDCTP 735
K + AP ++ P+ SS D+ SD ++ K+ S P P
Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP 299
Query: 736 HPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPG 795
S+ + K ++ + D SD + E PP + +++ P PA+
Sbjct: 300 PKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP-PPAKKA 358
Query: 796 A 796
A
Sbjct: 359 A 359
Score = 45.4 bits (106), Expect = 3e-04
Identities = 108/548 (19%), Positives = 189/548 (34%), Gaps = 112/548 (20%)
Query: 482 ACESACSEAESTAAETLDL---PLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPS 538
A ES+ SE S + D P+ + ++ + + S + DS S PP
Sbjct: 123 ASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPP-- 180
Query: 539 TGSLSNSRTLPSSSCLVAYKKTPPP---VPPRTTSKPFISVTVQSSTESAQDTYLDSQDH 595
N + + + A K PP P+ + S + SS+ S+ D DS++
Sbjct: 181 ----KNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSD---DSEEE 233
Query: 596 KSEVTSQSGLSN------------------SSDSLDSSTRPPSVTRGGVA--PAPEAPEP 635
K+ T + + SS S DSS+ + + P P + P
Sbjct: 234 KAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP 293
Query: 636 PPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPS 695
PP K GT P+ A +++ ++ + + S E+ P V++ +
Sbjct: 294 PPSAPPPKKSLGT-----QPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKA 348
Query: 696 SESSVPSHSMSSRRDTDSDTQDANDSSCKS-------SERSLPDCTPHPNSISIDAGPRQ 748
+ P+ + SD+ + D S + + P T ++ A P+Q
Sbjct: 349 TTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQ 408
Query: 749 ----APKIAQIKRNLSYGDNSDPALEAS------SLPPPDPWLETSSSSPAEPAQPGACR 798
K+ K + S + + E + P + + S PA+ A G+
Sbjct: 409 PVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGS-- 466
Query: 799 RDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFR 858
RD D ++ + EE K SAV +K Q+
Sbjct: 467 RDS-------------------SSDSDSSSSEEEEEKTSK--SAV-------KKKPQKVA 498
Query: 859 GLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKE 918
G A P A G + S D S + +E EK K
Sbjct: 499 G--------GAAPSKPASAKKGKAESSNSSSSDDSSEEEE---------------EKLKG 535
Query: 919 EKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSI 978
+ P P PK S KA+ S+++ +E +K + ++ S+++ E+A
Sbjct: 536 KGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEA 595
Query: 979 EIYVPEAQ 986
E P+A+
Sbjct: 596 E--TPQAK 601
Score = 39.3 bits (90), Expect = 0.018
Identities = 44/188 (23%), Positives = 74/188 (39%), Gaps = 35/188 (18%)
Query: 543 SNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTV----QSSTESAQDTYLDSQDHKSE 598
S+S SSS KK P+ T+K +S+ Q S +S+ D+ S + + E
Sbjct: 424 SSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEE 483
Query: 599 VTSQSGL--------------------------SNSSDSLDSSTRPPSVTRGGVAPAPEA 632
TS+S + SNSS S DSS +G +P P+A
Sbjct: 484 KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQA 543
Query: 633 PEPPPKHAALKSEQGTLTSSESHPEAAPKRKL----SSIGIQERTRRNGSHLSEDNGPKA 688
P+ +AL ++ G + E K+ S +++R + + +E K
Sbjct: 544 PKANGT-SALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK 602
Query: 689 IDVMAPSS 696
I + P++
Sbjct: 603 IKLQTPNT 610
Score = 37.0 bits (84), Expect = 0.092
Identities = 47/194 (24%), Positives = 76/194 (39%), Gaps = 36/194 (18%)
Query: 606 SNSSDSLDSSTRPPSV----TRGGVAPAPEAPEPPPKHAALKSEQGTLT-SSESHPEAAP 660
++SSDS DSS V + PA PP K AA SE + SS+ E
Sbjct: 82 ASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQ 141
Query: 661 KRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDAND 720
K++ G++ P+A AP P + SS D+DS ++D
Sbjct: 142 KKQPVQKGVK---------------PQAKAAKAP------PKKAKSSDSDSDSSSEDEPP 180
Query: 721 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPW 780
+ K P TP +++ A + PK A+ ++ G + + +SS D
Sbjct: 181 KNQK------PKITP----VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDS 230
Query: 781 LETSSSSPAEPAQP 794
E +++ + P
Sbjct: 231 EEEKAAATPKKTVP 244
>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
Length = 1894
Score = 46.6 bits (109), Expect = 1e-04
Identities = 71/323 (21%), Positives = 111/323 (34%), Gaps = 42/323 (13%)
Query: 488 SEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVS-------LQSLSPPPSTG 540
S +ST +PS+ S SH L + G ++E + + S S P +
Sbjct: 847 SSPQSTVPSRAHPRVPSH--SDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISR 904
Query: 541 SLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVT 600
+ R P + ++K P P P++T SS S S D +E
Sbjct: 905 GWEDLRRSPQRGASL-HRKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGH 963
Query: 601 SQSGLSNSSDSLDSSTRPP--------SVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSS 652
S S+D S RPP SV R +PPP A + G +
Sbjct: 964 SPKAQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRD 1023
Query: 653 ESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTD 712
+ P+ L+ G T + SH S D SS +P ++ ++ D
Sbjct: 1024 AGRSPSQPRLSLTQAGRPRPTSQGRSHSSS-------DPYTASSRGMLP----TALQNQD 1072
Query: 713 SDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEAS 772
D Q + D S+E D ++ PK Q++ G D +
Sbjct: 1073 EDAQGSYDDD--STEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHRSQRG 1130
Query: 773 SLPPPDPWLETSSSSPAEPAQPG 795
++SPA P++PG
Sbjct: 1131 -----------HAASPARPSRPG 1142
Score = 34.3 bits (77), Expect = 0.59
Identities = 69/305 (22%), Positives = 107/305 (35%), Gaps = 58/305 (19%)
Query: 377 DSDESGGSPKPSPKTAARRQSYLR-ATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEE 435
D+D G SPK P + R S R +S S PRR + P + P ++
Sbjct: 957 DADTEGHSPKAQPGSTDRHASPARPPAARSQQHPSVPRR----------MTPGRAPQ-QQ 1005
Query: 436 DYTPVSDSLNDSSCISQIFGQASLIPQLFGHE-------QQVREAELSDQYEAACESACS 488
PV+ S + S+ G++ P+L + Q R SD Y A+
Sbjct: 1006 PPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLP 1065
Query: 489 EA--------------ESTAAETLDLPLPSYFRSR--------SHSYLRA-IQAGCSQEE 525
A +ST E D+ P++ H + + AG +
Sbjct: 1066 TALQNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDH 1125
Query: 526 DSVSLQSLSP--PPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTE 583
S + SP P G + +PS + A K+ PP +SK SV+ + E
Sbjct: 1126 RSQRGHAASPARPSRPGGPQSRARVPSRA---APGKSEPPSKRPLSSKSQQSVSAEDDEE 1182
Query: 584 --------SAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVT---RGGVAPAPEA 632
+D S ++ G ++ SL R P++ RGG +
Sbjct: 1183 EDAGFFKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKR 1242
Query: 633 PEPPP 637
P PPP
Sbjct: 1243 PLPPP 1247
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 45.8 bits (107), Expect = 2e-04
Identities = 71/308 (23%), Positives = 116/308 (37%), Gaps = 38/308 (12%)
Query: 385 PKPSPKTAARRQSYLRATQQSLGEQSN------PRRSLDRLDSVDMLLPSKCPSWEEDYT 438
P PSP A + L A+ + Q P + + D L +CPS +
Sbjct: 2198 PYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV 2257
Query: 439 PVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACES--------ACSEA 490
P S + + L P FG ++ E + ++ A+ S S +
Sbjct: 2258 PESPGVGGGKASEPL-----LSPPPFGESRKALEVK-KEELGASSPSYGPPNLGFVDSPS 2311
Query: 491 ESTAAETLDLPLPSYFRSRSHSYLRAIQAGCS----QEEDSVSLQSLSP-PPSTGSL--S 543
T L+L P F++ ++ + ++ Q+L+P PPS +
Sbjct: 2312 SGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRP 2371
Query: 544 NSRTLPSSSCLVAYKKTPPP------VPPRTT-SKPFISVTVQSSTESAQDTYLDSQDHK 596
S T P + + + PPP +PPR+ S PF V ++S+ + L +
Sbjct: 2372 GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLS 2431
Query: 597 SEVTSQSGLSNSSDSLDSSTRPPS--VTRGGVAPAPEAPEPPPKHAALKSEQGTLTS--S 652
+E S ++ S D +RPPS +R AP + P P P A K+ TS +
Sbjct: 2432 AEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGA 2491
Query: 653 ESHPEAAP 660
P A P
Sbjct: 2492 GGFPAALP 2499
Score = 31.2 bits (69), Expect = 5.0
Identities = 58/265 (21%), Positives = 85/265 (32%), Gaps = 52/265 (19%)
Query: 533 LSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDS 592
LSPPP LS P SS +++P P + P + + E++
Sbjct: 494 LSPPPEESPLSPP---PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP------ 544
Query: 593 QDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALK---SEQGTL 649
S +S LS + L +S PP +R P PPP+ + +
Sbjct: 545 ---LSPPFEESPLSPPPEELPTSP-PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
Query: 650 TSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRR 709
E P + P + S LS P+A + P P S S
Sbjct: 601 PPFEESPLSPPPEE--------------SPLSPP--PEASRLSPP------PEDSPMSPP 638
Query: 710 DTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPAL 769
+S + S S + +P P + P ++P + P
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP--------------TSPPP 684
Query: 770 EASSLPPPDPWLETSSSSPAEPAQP 794
EAS L PP TS PA P
Sbjct: 685 EASRLSPPPEDSPTSPPPEDSPASP 709
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 45.4 bits (106), Expect = 3e-04
Identities = 77/367 (20%), Positives = 128/367 (34%), Gaps = 42/367 (11%)
Query: 460 IPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLP----LPSYFRSRSHSY-- 513
+P G + + L + E E ++ LD P LP+ R R S
Sbjct: 143 VPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKG 202
Query: 514 --LRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTL----PSSSCLVAYKKTPPPVPPR 567
L + + S++ Q + P S + +S L P L K+ P
Sbjct: 203 DTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKP 262
Query: 568 TTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVA 627
+K F T ++ Q T KS T+QS S T G +
Sbjct: 263 LETKSFTPKTKTKTSSPGQKT-------KSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRS 315
Query: 628 PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQER---TRRNGSHLSEDN 684
+P++P+ P + + P A K+S IQ + T + L+ +N
Sbjct: 316 KSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSEN 375
Query: 685 GPKAIDVMAPSSESSVPS--HSMSSRRDTD-----SDTQDANDSSCKSSERSLPDCTPHP 737
PK V + E+S+ + + R+ D S ++ D S P+CT
Sbjct: 376 QPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPK 435
Query: 738 NSISIDAGPRQAPKIAQIKRNLSYGDNS---DPALEA----------SSLPPPDPWLETS 784
S S + + + S DNS D +++ S++PP P++ +
Sbjct: 436 ASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSP 495
Query: 785 SSSPAEP 791
S SP P
Sbjct: 496 SVSPPTP 502
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 45.1 bits (105), Expect = 3e-04
Identities = 135/696 (19%), Positives = 240/696 (34%), Gaps = 117/696 (16%)
Query: 378 SDESGGSPKPSPKTAARRQSYLR-ATQQSLGEQSNPRRSLDRLDS--------VDMLLPS 428
S+E G S P+ RR S +R A L E S P + ++ D L +
Sbjct: 210 SEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKT 269
Query: 429 KCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACS 488
+ EE+ D + Q +A ++ + +++ + + + ++
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329
Query: 489 EAE---------STAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPST 539
E E + E L + + ++ + + S L+ S PS
Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSP 389
Query: 540 GSLSNSRTLPSSSCL----VAYKKTPPPVPPRTTSKPFISVTVQSSTE------------ 583
L+ R S L + ++TPPP+ + S P + S E
Sbjct: 390 PRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVL 449
Query: 584 ---SAQDTYLDSQD---HKSEVTSQSGLSNSSDSLDSSTRPPS--VTRGGVAPAPEAPEP 635
S +T D+++ + V GLS S D+ P+ V V P +
Sbjct: 450 IQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTL 509
Query: 636 PPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPS 695
A E + S++ P + L+ GI E + S L + G +A
Sbjct: 510 ADYSAQKDLEPESDRSAQPLPLKIEELALAK-GITEECLKQPS-LEQKEGRRA------- 560
Query: 696 SESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISI------------D 743
S + +PSH + D+ S ++ SS S PD + + +
Sbjct: 561 SHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTH 620
Query: 744 AGPRQAPKIAQIKRNLSYGDNSDPALEAS-----SLPPPDPWLETSSSSPAEPAQPGACR 798
A PR PK+ + S + + AS SL P SS+S E P + +
Sbjct: 621 ANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVS--RDSSTSYTETKDPSSGQ 678
Query: 799 RDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFR 858
+ LQ C+ + T + S V + LS SA+ ++Q+ Q R
Sbjct: 679 EVATPPVPQLQV---------CEPKERTSTS--SSSVQARRLSQPESAEKHVTQRLQPER 727
Query: 859 GLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQL-VETPEKRK 917
G ++ +A P Q L + + ++H ++ ++T E R
Sbjct: 728 GSPKKCEAEEAEPPAATQPQTSETQTSHLP------ESERIHHTVEEKEEVTMDTSENRP 781
Query: 918 EEKKPPPPVP------------------KKPAKSKPAVSRDK-----------ASDASDK 948
E P PP+P +K S P + K A ++ +
Sbjct: 782 ENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTE 841
Query: 949 QRQEARKRLLAAKRAASVRQNSATESADSIEIYVPE 984
Q RKR A A + ++ S + + +S++ +P+
Sbjct: 842 GGQPGRKRRWGASTATTQKKPSISITTESLKSLIPD 877
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 45.1 bits (105), Expect = 3e-04
Identities = 42/151 (27%), Positives = 63/151 (41%), Gaps = 11/151 (7%)
Query: 533 LSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTES-AQDTYL- 590
L PP + + +P S + + PP P T+S+P++ S ++S +YL
Sbjct: 143 LESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLA 202
Query: 591 -DSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAP----APEAPEPPPKHAALKS- 644
S +SQS LS+S L SS PS G + AP P PP +
Sbjct: 203 PTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQ 262
Query: 645 ---EQGTLTSSESHPEAAPKRKLSSIGIQER 672
E G S +AAP+ S++ QE+
Sbjct: 263 EPLESGAKNKSTEQQQAAPEPDPSTMTPQEQ 293
>gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo
sapiens]
Length = 1075
Score = 44.7 bits (104), Expect = 4e-04
Identities = 79/395 (20%), Positives = 145/395 (36%), Gaps = 39/395 (9%)
Query: 402 TQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIP 461
T +++ + P S LD + L S W +S+ S++ +
Sbjct: 338 TPETVPRSTKPTTS-SALDVSETTLASSEKPWIVPTAKISED-------SKVLQPQTATY 389
Query: 462 QLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGC 521
+F E E+SD Y A + + TL+ P + S + + ++
Sbjct: 390 DVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFT 449
Query: 522 SQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSS 581
S E +Q +P P + ++PS+ K P P RTTS I+ + S
Sbjct: 450 SPE-----MQPTTPAPQ-----QTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKS 499
Query: 582 TESAQDTYLDSQDH----KSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPP 637
E T + K ++ ++++ + + R P + P +P P
Sbjct: 500 PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVP 559
Query: 638 K-HAALKSEQGTLTSSE-SHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPS 695
K + ++ T S E S+ APK L ++ E G I +++PS
Sbjct: 560 KVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPS 619
Query: 696 SESSVPSHSMSSRRDTDSDTQDANDSSC-KSSERSLPDCTPH----------PNSISIDA 744
++ +TD TQ+ + +++E + PH + I
Sbjct: 620 PSQ---EELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRP 676
Query: 745 GPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDP 779
G +QAP+ + RN+S D++ P + + PP P
Sbjct: 677 GVKQAPRPSGADRNVSV-DSTHPTKKPGTRRPPLP 710
>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo
sapiens]
Length = 1233
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/119 (31%), Positives = 60/119 (50%), Gaps = 14/119 (11%)
Query: 526 DSVS---LQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSST 582
DS+S +Q++ PP S+ +S T+ S S + +TPP T + P VT S T
Sbjct: 295 DSLSCPVMQNVQPPKSSPVVS---TVLSGSSGSSSTRTPP-----TANHPVEPVT--SVT 344
Query: 583 ESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPE-APEPPPKHA 640
+ ++ D S +S S + NS D+L+ + P ++ +PAP+ APEP P A
Sbjct: 345 QPSELLQQKGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASA 403
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 44.3 bits (103), Expect = 6e-04
Identities = 65/268 (24%), Positives = 98/268 (36%), Gaps = 32/268 (11%)
Query: 534 SPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQ 593
SP S+ SN LP + K PPP PP V + S Q
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP---------VGNRPSIHREAVPPPPPQ 288
Query: 594 DHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAP-------EAPEPPPKHAALKSEQ 646
++K V S S SS + PP +R G P P E P P ++ +L S
Sbjct: 289 NNKPPVPSTPRPSASSQA---PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
Query: 647 GTLTS-SESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSM 705
L S S P P + +++ R+G P + +S + + +
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP----PPPVSRNGSTSRALPATPQL 401
Query: 706 SSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNS 765
SR DS S P P S SI G + +P + + + S
Sbjct: 402 PSRSGVDSPRSGPRPP-LPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460
Query: 766 DPALEASSLPPPDPWLETSSSSPAEPAQ 793
D LPPP+P+++T+ S P++ A+
Sbjct: 461 D-------LPPPEPYVQTTKSYPSKLAR 481
Score = 32.0 bits (71), Expect = 2.9
Identities = 50/205 (24%), Positives = 68/205 (33%), Gaps = 40/205 (19%)
Query: 602 QSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK 661
QS LS+SS + PP+ +R + P PPP + H EA P
Sbjct: 237 QSPLSSSSPFSNRPPLPPTPSRA----LDDKPPPPPPPVGNRPS--------IHREAVPP 284
Query: 662 RKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSD---TQDA 718
++N P PS+ S P R +
Sbjct: 285 PP-----------------PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 719 NDSSCKSSER--SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 776
ND + + +R SL TP P +GP P + + DP + LPP
Sbjct: 328 NDETPRLPQRNLSLSSSTP-PLPSPGRSGPLPPPPSERPPPPVR-----DPPGRSGPLPP 381
Query: 777 PDPWLETSSSSPAEPAQPGACRRDG 801
P P S+S A PA P R G
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSG 406
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 44.3 bits (103), Expect = 6e-04
Identities = 65/268 (24%), Positives = 98/268 (36%), Gaps = 32/268 (11%)
Query: 534 SPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQ 593
SP S+ SN LP + K PPP PP V + S Q
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP---------VGNRPSIHREAVPPPPPQ 288
Query: 594 DHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAP-------EAPEPPPKHAALKSEQ 646
++K V S S SS + PP +R G P P E P P ++ +L S
Sbjct: 289 NNKPPVPSTPRPSASSQA---PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
Query: 647 GTLTS-SESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSM 705
L S S P P + +++ R+G P + +S + + +
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP----PPPVSRNGSTSRALPATPQL 401
Query: 706 SSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNS 765
SR DS S P P S SI G + +P + + + S
Sbjct: 402 PSRSGVDSPRSGPRPP-LPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460
Query: 766 DPALEASSLPPPDPWLETSSSSPAEPAQ 793
D LPPP+P+++T+ S P++ A+
Sbjct: 461 D-------LPPPEPYVQTTKSYPSKLAR 481
Score = 32.0 bits (71), Expect = 2.9
Identities = 50/205 (24%), Positives = 68/205 (33%), Gaps = 40/205 (19%)
Query: 602 QSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK 661
QS LS+SS + PP+ +R + P PPP + H EA P
Sbjct: 237 QSPLSSSSPFSNRPPLPPTPSRA----LDDKPPPPPPPVGNRPS--------IHREAVPP 284
Query: 662 RKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSD---TQDA 718
++N P PS+ S P R +
Sbjct: 285 PP-----------------PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 719 NDSSCKSSER--SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 776
ND + + +R SL TP P +GP P + + DP + LPP
Sbjct: 328 NDETPRLPQRNLSLSSSTP-PLPSPGRSGPLPPPPSERPPPPVR-----DPPGRSGPLPP 381
Query: 777 PDPWLETSSSSPAEPAQPGACRRDG 801
P P S+S A PA P R G
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSG 406
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 43.1 bits (100), Expect = 0.001
Identities = 55/214 (25%), Positives = 83/214 (38%), Gaps = 20/214 (9%)
Query: 533 LSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDS 592
LSP ST S + PS + + T P P T S S T +S S T +
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097
Query: 593 QDHKSEVTSQSGLSNSS-DSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTS 651
S V+ +S S+S S ++ P S T G+ + EP H++ S + TL+
Sbjct: 4098 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGL-----SQEPTTSHSSQGSTEATLSP 4152
Query: 652 SESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDT 711
+ SS+G Q T + +E + + E+S P+HS + T
Sbjct: 4153 GST--------TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 4204
Query: 712 ------DSDTQDANDSSCKSSERSLPDCTPHPNS 739
+ T +S+ S S D TP P S
Sbjct: 4205 TLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPS 4238
Score = 42.4 bits (98), Expect = 0.002
Identities = 120/544 (22%), Positives = 191/544 (35%), Gaps = 64/544 (11%)
Query: 218 FRSSGPASGLMTLGRQAERS--QPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPA 275
F S +SG++ + S PR + ++ S + + T + P+PP+
Sbjct: 2650 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPS 2709
Query: 276 TCPSLGVGTDTNYVKRGSWSTL------TLSHAHEVCQKTSATLDKSLLKSKSCHQGLAY 329
T + + T + GS T T S E ++ D S S H
Sbjct: 2710 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHS---- 2765
Query: 330 HYLQVPGGGGEWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSP 389
G GE +T+ +SP T+ +P GS E S SP+ SP
Sbjct: 2766 ----TTSGRGESTTSRISPGSTEITT---LP------GSTTTPGLSEASTTFYSSPR-SP 2811
Query: 390 KTAARRQSYLRATQQSLGEQSNPRRSLD-RLDSVDMLLPSKCPSWEEDYTPVSDSLNDSS 448
T S T +GE+S RS S + P E+ T V S + S
Sbjct: 2812 TTTLSPASM---TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS-SPGS 2867
Query: 449 CISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRS 508
+ +F + S + G E + + + + + T T P+ ++
Sbjct: 2868 TETTVFPR-STTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 2926
Query: 509 RSHSYLRAIQAGCSQEEDSVSLQS--------LSPPPSTGSLSNSRTLPSSSCLVAYKKT 560
+ L G E+S + S LSP ST S + PS + + T
Sbjct: 2927 GLPATLTTADLG----EESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETT 2982
Query: 561 PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSS-DSLDSSTRPP 619
P P T S S T +S S T + S V+ +S S+S S ++ P
Sbjct: 2983 TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD 3042
Query: 620 SVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSH 679
S T G+ + EP H++ S + TL+ + SS+G Q T +
Sbjct: 3043 STTTSGL-----SQEPTASHSSQGSTEATLSPGST--------TASSLGQQSTTFHSSPG 3089
Query: 680 LSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDA------NDSSCKSSERSLPDC 733
+E + + E+S P+HS + T + +S+ S S D
Sbjct: 3090 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDT 3149
Query: 734 TPHP 737
TP P
Sbjct: 3150 TPSP 3153
Score = 42.4 bits (98), Expect = 0.002
Identities = 137/594 (23%), Positives = 211/594 (35%), Gaps = 83/594 (13%)
Query: 197 SRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQA-----ERSQPRYFMHAYNTISG 251
+ S +S ++ L E+ SS P S T+ ++ R +P F H+ S
Sbjct: 3922 THSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTF-HS-RPAST 3979
Query: 252 HMLKTTKNNTT-----ELTAPPPPPAP-----PATCPSLGVGTDTNYVKRGSWSTLT-LS 300
H T+++TT E TA P PA PAT + +G ++ S ST T LS
Sbjct: 3980 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLS 4039
Query: 301 HAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIP 360
A S L S P + +T SPR DA
Sbjct: 4040 PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 4099
Query: 361 CR----------RMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLR-----ATQQS 405
+ GS + + SG S +P+ +++ + T S
Sbjct: 4100 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASS 4159
Query: 406 LGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQ--ASLIPQL 463
LG+QS S D+ LLP D T S + S+ G +L P
Sbjct: 4160 LGQQSTTFHSSPG-DTETTLLP--------DDTITSGLVEASTPTHSSTGSLHTTLTPAS 4210
Query: 464 FGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHS----YLRAIQA 519
E+ + ++ ++ S +TA + + + + + SR S + A
Sbjct: 4211 STSTGLQEESTTFQSWPSSSDTTPSPPSTTA---VPVEVSTTYHSRPSSTPTTHFSASST 4267
Query: 520 GCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPP---------PVPPRTTS 570
+ E+S ++ S P +TG+ + T ++S LV T P +P TT+
Sbjct: 4268 TLGRSEESTTVHS--SPGATGT-ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 4324
Query: 571 KPFI--SVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD-SLDSSTRPPSVTRGGVA 627
S T SS S T + S V+ +S S+S S+ ++ P S T GV+
Sbjct: 4325 AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVS 4384
Query: 628 PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPK 687
A P G+ T+S PE+ SS G E T L DN
Sbjct: 4385 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH--SSPGSTETT------LLPDN--- 4433
Query: 688 AIDVMAPSSESSVPSHSMSSRRDTD----SDTQDANDSSCKSSERSLPDCTPHP 737
+ E+S P HS + T T +S+ S + D TP P
Sbjct: 4434 --TTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 4485
Score = 39.3 bits (90), Expect = 0.018
Identities = 118/543 (21%), Positives = 187/543 (34%), Gaps = 62/543 (11%)
Query: 218 FRSSGPASGLMTLGRQAERS--QPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPA 275
F S +SG++ + S PR + ++ S + + T + P+PP+
Sbjct: 1093 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 1152
Query: 276 TCPSLGVGTDTNYVKRGSWSTL------TLSHAHEVCQKTSATLDKSLLKSKSCHQGLAY 329
T + + T + GS T T S E ++ D S S H
Sbjct: 1153 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHS---- 1208
Query: 330 HYLQVPGGGGEWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSP 389
G GE +T+ +SP T+ +P GS E S SP+ SP
Sbjct: 1209 ----TTSGRGESTTSRISPGSTEITT---LP------GSTTTPGLSEASTTFYSSPR-SP 1254
Query: 390 KTAARRQSYLRATQQSLGEQSNPRRSLD-RLDSVDMLLPSKCPSWEEDYTPVSDSLNDSS 448
T S T +GE+S RS S + P E+ T V S S+
Sbjct: 1255 TTTLSPASM---TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGST 1311
Query: 449 CISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRS 508
+ +F S + G E + + + + + T T P+ ++
Sbjct: 1312 -ETTVFPH-STTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 1369
Query: 509 RSHSYLRAIQAGCSQEEDSVSLQS--------LSPPPSTGSLSNSRTLPSSSCLVAYKKT 560
+ L G E+S + S LSP ST S + PS + + T
Sbjct: 1370 GLPATLTTADLG----EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETT 1425
Query: 561 PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 620
P P T S S T +S S T + S V+ +S S+S +T P
Sbjct: 1426 TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD 1485
Query: 621 VTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHL 680
T + + EP H++ S + TL+ + SS+G Q T +
Sbjct: 1486 ST----TTSDLSQEPTTSHSSQGSTEATLSPGST--------TASSLGQQSTTFHSSPGD 1533
Query: 681 SEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDA------NDSSCKSSERSLPDCT 734
+E + + E+S P+HS + T + +S+ S S D T
Sbjct: 1534 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 1593
Query: 735 PHP 737
P P
Sbjct: 1594 PSP 1596
Score = 38.5 bits (88), Expect = 0.031
Identities = 124/527 (23%), Positives = 179/527 (33%), Gaps = 83/527 (15%)
Query: 256 TTKNNTTELTAPPPPPAP-----PATCPSLGVGTDTNYVKRGSWSTLT-LSHAHEVCQKT 309
TT T E TA P PA PAT + +G ++ S ST T LS A
Sbjct: 1349 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 1408
Query: 310 SATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIPCRRMRSGSY 369
S L S P + +T SPR DA P SG
Sbjct: 1409 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS---PATTTSSGV- 1464
Query: 370 IKAMGDEDSDESGGSP-----------------KPSPKTAARRQSYLRAT-------QQS 405
E+S S P P T+ Q AT S
Sbjct: 1465 -----SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASS 1519
Query: 406 LGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQ--ASLIPQL 463
LG+QS S D+ LLP D T S + S+ G +L P
Sbjct: 1520 LGQQSTTFHSSPG-DTETTLLP--------DDTITSGLVEASTPTHSSTGSLHTTLTPAS 1570
Query: 464 FGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHS----YLRAIQA 519
E+ + ++ ++ S +TAA + + + + SR S + A
Sbjct: 1571 STSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP---VEVSTTYHSRPSSTPTTHFSASST 1627
Query: 520 GCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPP---------PVPPRTTS 570
+ E+S ++ S P +TG+ + T ++S LV T P +P TT+
Sbjct: 1628 TLGRSEESTTVHS--SPGATGT-ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 1684
Query: 571 KPFI--SVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTR-PPSVTRGGVA 627
S T SS S T + S V+ +S S+S +T P S T GV+
Sbjct: 1685 AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVS 1744
Query: 628 PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPK 687
A P G+ T+S PE+ SS G E T L DN
Sbjct: 1745 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH--SSPGSTETT------LLPDNTTA 1796
Query: 688 A--IDVMAP-SSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLP 731
+ ++ P S + P ++S T + S SS+ ++P
Sbjct: 1797 SGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1843
Score = 37.4 bits (85), Expect = 0.070
Identities = 71/294 (24%), Positives = 101/294 (34%), Gaps = 26/294 (8%)
Query: 524 EEDSVSLQSLSPPPSTGSLSNSRTLPSS-------SCLVAYKKTPPPVPPRTTSKPFISV 576
E + S S S P+T ++S TL S S VA TP P T+ S
Sbjct: 1854 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 1913
Query: 577 TVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPP 636
SS S Q + S + +S S+SS + S+ PPS T V P
Sbjct: 1914 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS-PPSTTSALVEEPTSYHSSP 1972
Query: 637 PKHAALKSEQGTLTSSESHPEAA-------------PKRKLSSIGIQERTRRNGSHLSED 683
A + TS S A P R +S+ + E T S S +
Sbjct: 1973 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 2032
Query: 684 NGPKAIDVMAPS-SESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISI 742
P SE S H SS R + A+ +S SE S + P S
Sbjct: 2033 TTALPGSTTTPGLSEKSTTFH--SSPRSPATTLSPASTTSSGVSEESTTSHS-RPGSTHT 2089
Query: 743 DAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGA 796
A P + + R+ + +S + + + LP S S + PG+
Sbjct: 2090 TAFP-DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGS 2142
Score = 35.8 bits (81), Expect = 0.20
Identities = 55/228 (24%), Positives = 88/228 (38%), Gaps = 36/228 (15%)
Query: 564 VPPRTTSKPFI--SVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSV 621
+P R+T+ + S T S+ S + T L T+ GLS S + SS R P+
Sbjct: 925 LPARSTTSVLLGESTTSPISSGSMETTALPGS------TTTPGLSERSTTFHSSPRSPAT 978
Query: 622 TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLS 681
T ++PA + + + T + + P++ LS + T + S S
Sbjct: 979 T---LSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLS----RHSTTSHSSPGS 1031
Query: 682 EDNG--PKAIDVMAPSSESSVPSHSMSSRRDT--------------DSDTQDANDSSCKS 725
D P + PS ES+ SHS S DT +S T +N S +
Sbjct: 1032 TDTTLLPASTTTSGPSQESTT-SHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHT 1090
Query: 726 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASS 773
+ PD T +S ++A R + LS ++ P L+ S
Sbjct: 1091 T--LFPDST--TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 1134
Score = 33.1 bits (74), Expect = 1.3
Identities = 48/224 (21%), Positives = 82/224 (36%), Gaps = 28/224 (12%)
Query: 564 VPPRTTSKPFI--SVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSV 621
+P R+T+ + S T S+ S + T L T+ GLS S + SS R P+
Sbjct: 3565 LPARSTTSVLLGESTTSPISSGSMETTALPGS------TTTPGLSEKSTTFHSSPRSPAT 3618
Query: 622 TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLS 681
T ++PA + + + T + + P++ LS T + +
Sbjct: 3619 T---LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSR---HSTTSHSSPGST 3672
Query: 682 EDNGPKAIDVMAPSSESSVPSHSMSSRRDT------------DSDTQDANDSSCKSSERS 729
+ A + SS+ S SHS S DT ++ + S +
Sbjct: 3673 DTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 3732
Query: 730 LPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASS 773
PD T +S ++A R + LS ++ P L+ S
Sbjct: 3733 FPDST--TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 3774
Score = 32.7 bits (73), Expect = 1.7
Identities = 40/153 (26%), Positives = 55/153 (35%), Gaps = 8/153 (5%)
Query: 524 EEDSVSLQSLSPPPSTGSLSNSRTLPSS-------SCLVAYKKTPPPVPPRTTSKPFISV 576
E+ + S S P+T ++S TL S S VA TP P T+ S
Sbjct: 4687 EKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 4746
Query: 577 TVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPP 636
SS S Q + S + +S S+SS + S+ PPS T V P
Sbjct: 4747 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS-PPSTTSALVEEPTSYHSSP 4805
Query: 637 PKHAALKSEQGTLTSSESHPEAAPKRKLSSIGI 669
A + + TS S A + GI
Sbjct: 4806 GSIATTHFPESSTTSGRSEESTASHSSPDTNGI 4838
Score = 32.3 bits (72), Expect = 2.3
Identities = 66/279 (23%), Positives = 100/279 (35%), Gaps = 43/279 (15%)
Query: 529 SLQSLSPPPSTGSL---SNSRTL-----PSSSCLVAYKKTPPPVPPRTTSKPFI--SVTV 578
S S S P +TG+ S+S T P +S + + +P TT+ S T
Sbjct: 224 STVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTF 283
Query: 579 QSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTR-PPSVTRGGVAPAPEAPEPPP 637
SS S T ++ S V+ +S S+S + P S T GV+ A P
Sbjct: 284 YSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIP 343
Query: 638 KHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSE 697
GT T S PE+ SS G + TR L ++ + E
Sbjct: 344 GSTDTTLSPGTTTPSSLGPESTTFH--SSPGYTKTTR-----LPDNTTTSGL------LE 390
Query: 698 SSVPSHSMSSRRDT----DSDTQDANDSSCKSSERSLPDCTPHPN---------SISIDA 744
+S P HS + T S T + + S S D +P P+ S + +
Sbjct: 391 ASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHS 450
Query: 745 GPRQAP--KIAQIKRNLSYGDNSDPA----LEASSLPPP 777
P P + L + + S P + ++ PPP
Sbjct: 451 SPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPP 489
Score = 32.3 bits (72), Expect = 2.3
Identities = 119/537 (22%), Positives = 178/537 (33%), Gaps = 95/537 (17%)
Query: 256 TTKNNTTELTAPPPPPAP-----PATCPSLGVGTDTNYVKRGSWST-LTLSHAHEVCQKT 309
TT T E TA P PA PAT + +G ++ S ST TLS A
Sbjct: 2906 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2965
Query: 310 SATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIPCR------- 362
S L S P + +T SPR DA
Sbjct: 2966 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 3025
Query: 363 ---RMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLR-----ATQQSLGEQSNPRR 414
+ GS + + SG S +P+ +++ + T SLG+QS
Sbjct: 3026 STSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFH 3085
Query: 415 SLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQ--ASLIPQLFGHEQQVRE 472
S D+ LLP D T S + S+ G +L P E
Sbjct: 3086 SSPG-DTETTLLP--------DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEE 3136
Query: 473 AELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHS----YLRAIQAGCSQEEDSV 528
+ + ++ ++ S +TAA + + + + SR S + A + E+S
Sbjct: 3137 STTFQSWPSSSDTTPSPPGTTAAP---VEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 3193
Query: 529 SLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDT 588
++ S P +TG+ + T ++S LV T P S+ S + T
Sbjct: 3194 TVHS--SPGATGT-ALFPTRSATSVLVGEPTTSP-----------------ISSGSTETT 3233
Query: 589 YLDSQDHKSEVTSQSGLSNSSDSLDSSTR-------PPSVTRGGVAPAPEAPEPPPKHAA 641
L T+ +GLS S + SS R P S T GV+ P
Sbjct: 3234 ALPGS------TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH 3287
Query: 642 LKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDV-MAPSS---- 696
+ G+ T E+ SS G + T GS + GP++ P S
Sbjct: 3288 TTAFPGSTTMPGVSQESTASH--SSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETT 3345
Query: 697 ------------ESSVPSHSMSSRRDTD----SDTQDANDSSCKSSERSLPDCTPHP 737
E+S P HS + T T +S+ S + D TP P
Sbjct: 3346 LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 3402
Score = 31.2 bits (69), Expect = 5.0
Identities = 57/241 (23%), Positives = 88/241 (36%), Gaps = 42/241 (17%)
Query: 507 RSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPP 566
RS ++L A E+S + S T + S T+P S + P P
Sbjct: 644 RSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPG-PT 702
Query: 567 RTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVT------SQSGLSNSSDSLDSSTRPP- 619
TT P + +S+ + T S+ +E T + SGL +S + SSTR P
Sbjct: 703 DTTLSPG---STTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPH 759
Query: 620 -------SVTRGGVAPA--------PEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKL 664
S TR G + P PP +A T+S P + P +
Sbjct: 760 TTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS---TTSHGSPSSIPTTHI 816
Query: 665 SSIG-----IQERTRRNGS-------HLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTD 712
S+ ++E T + S H E + + +S SS +H++SS T
Sbjct: 817 SARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST-THTISSAPSTT 875
Query: 713 S 713
S
Sbjct: 876 S 876
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 42.7 bits (99), Expect = 0.002
Identities = 64/259 (24%), Positives = 92/259 (35%), Gaps = 24/259 (9%)
Query: 525 EDSVSLQSLSPPPSTG----SLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQS 580
E + + +PPP ++ T S+ PPP PPR +SK +
Sbjct: 235 EGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPK 294
Query: 581 STESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHA 640
+ Q + TS S+SS S + S TRG A P K
Sbjct: 295 PSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKAL 354
Query: 641 ALK---SEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSE 697
++ SE SES +++P SS + S + GP V SE
Sbjct: 355 EVEESNSEDEASFKSES-AQSSPSNSSSSSDSSSDSDFEPSQ-NHSQGPLRSMVEDLQSE 412
Query: 698 SSVPSHSMSSR---------RDT-----DSDTQDANDSSCKSSERSLPDCTPHPNS-ISI 742
S S S RD+ DS++ ++ DSS S E P P PNS +S
Sbjct: 413 ESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSG 472
Query: 743 DAGPRQAPKIAQIKRNLSY 761
P K +I + +Y
Sbjct: 473 RRSPESCSKPEKILKKGTY 491
Score = 38.9 bits (89), Expect = 0.024
Identities = 53/239 (22%), Positives = 87/239 (36%), Gaps = 26/239 (10%)
Query: 566 PRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD----SSTRPPSV 621
P+ T S + + +++H+ S +SS L+ S++ S
Sbjct: 172 PKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSR 231
Query: 622 TRGGVAPAPEAPEPPPKHA------ALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRR 675
G E PPPK A ALK + TS + P P + + T
Sbjct: 232 KLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPAT-- 289
Query: 676 NGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTP 735
++ P A SS+ S + S R + S D + KSS R
Sbjct: 290 -----ADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRG------ 338
Query: 736 HPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP-PDPWLETSSSSPAEPAQ 793
+ ++ PR+A K +++ + S + S + A S P ++SS S EP+Q
Sbjct: 339 --EKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQ 395
Score = 32.3 bits (72), Expect = 2.3
Identities = 71/371 (19%), Positives = 128/371 (34%), Gaps = 41/371 (11%)
Query: 604 GLSNSSDSLDSSTRP----PSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHP--- 656
G+ + D+ +RP P + ++ + + P H + + + + +S+ H
Sbjct: 140 GVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTK 199
Query: 657 --EAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDSD 714
P++ S + R + S+D K + P E + P +
Sbjct: 200 EHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALK 259
Query: 715 TQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSL 774
+S K P P +S P + K++ S G S P +
Sbjct: 260 ETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTS 319
Query: 775 PPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEE 834
+SS S +PA+ + R + ++AE+E E + E +E+N +E
Sbjct: 320 -------SSSSFSDKKPAKDKSSTRG-----EKVKAESEPREA---KKALEVEESNSEDE 364
Query: 835 VLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANP-RPTAQDLAGFWDLLQLSIEDIS 893
K SA S S E + N P R +DL + S ED S
Sbjct: 365 ASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQS-----EESDEDDS 419
Query: 894 MKFDELY---------HLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD 944
+E L + + + + ++PPPP P SK VS ++ +
Sbjct: 420 SSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSK--VSGRRSPE 477
Query: 945 ASDKQRQEARK 955
+ K + +K
Sbjct: 478 SCSKPEKILKK 488
Score = 32.0 bits (71), Expect = 2.9
Identities = 28/113 (24%), Positives = 43/113 (38%), Gaps = 7/113 (6%)
Query: 167 NGSKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASG 226
+GSK E K + + P++ S S SS L+ E +SS S
Sbjct: 179 HGSKDANKESSKTSKPHKVTKEHRERPRKDSESK-----SSSKELEREQA--KSSKDTSR 231
Query: 227 LMTLGRQAERSQPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPS 279
+ GR + + A+ + +T +T+ PPPPP PP S
Sbjct: 232 KLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASS 284
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 42.7 bits (99), Expect = 0.002
Identities = 73/354 (20%), Positives = 131/354 (37%), Gaps = 53/354 (14%)
Query: 404 QSLGEQSNPRRSLDRLDSVDMLLPSKCPSWE---EDYTPVSDSLND-----SSCISQIFG 455
+S+ Q P + +D D PS+ P + EDY + D + ++++
Sbjct: 282 KSVAMQQKPTAYVRPMDGQDQA-PSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKM 340
Query: 456 QASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHSYLR 515
+ + Q + +E E L + + + + AE P P+ + ++
Sbjct: 341 PSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPT----KDSQHVS 396
Query: 516 AIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFIS 575
++ Q + S S S ++ L + L S + + P PP +++ P
Sbjct: 397 SVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSED--SDSEQTPEKPPSSSAPP--- 451
Query: 576 VTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGV-APAPEAPE 634
S+ +S + + +E S S +SSDS S+ S + PAPE PE
Sbjct: 452 ----SAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPE-PE 506
Query: 635 PPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAP 694
PP + K + + S P A P+ GP++ +
Sbjct: 507 PPTTN---KWQLDNWLTKVSQPAAPPE-----------------------GPRSTEPPRR 540
Query: 695 SSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQ 748
ES S S +S+ S+++D S + R+ P+ PHP S P Q
Sbjct: 541 HPESKGSSDSATSQE--HSESKDPPPKSSSKAPRAPPE-APHPGKRSCQKSPAQ 591
Score = 42.0 bits (97), Expect = 0.003
Identities = 90/380 (23%), Positives = 137/380 (36%), Gaps = 53/380 (13%)
Query: 365 RSGSYIKAMGDED-------SDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLD 417
R+GS G+ + S + KP KT R RA + + + P S
Sbjct: 614 RAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRP----RAAASNEPKPAVPPSSEK 669
Query: 418 RLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSD 477
+ + PSK S E P D++ D + +L+P E Q S
Sbjct: 670 KKHKSSLPAPSKALSGPE---PAKDNVEDRTP-----EHFALVPLT---ESQGPPHSGSG 718
Query: 478 QYEAACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCS-QEEDSVSLQSLSP- 535
+ C A E + + L LPL ++ S LR S + ++ L S P
Sbjct: 719 SRTSGCRQAVVVQEDSRKDRLPLPLRD---TKLLSPLRDTPPPQSLMVKITLDLLSRIPQ 775
Query: 536 PPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDH 595
PP GS A K PP ++ K + + + + + D +
Sbjct: 776 PPGKGSRQRK----------AEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNK 825
Query: 596 K----SEVTSQSGLSNSSDSLDSSTRP--PSVTRGGVAPAPEAP-----EPPPKHAALKS 644
K E+ SQS S+SS S T+P PS P P + P K A +S
Sbjct: 826 KIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRS 885
Query: 645 EQGTLTSSESHPEAAPKRKL----SSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSV 700
+ T + P++A K SSI Q R GS S ++ + D P S+
Sbjct: 886 RREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSL 945
Query: 701 PS-HSMSSRRDTDSDTQDAN 719
P+ +S + D Q A+
Sbjct: 946 PNGNSKPGKPQVKFDKQQAD 965
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/259 (22%), Positives = 99/259 (38%), Gaps = 25/259 (9%)
Query: 485 SACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSN 544
+A + ST + + + S + S A + S S + S +T S ++
Sbjct: 89 TATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGAS 148
Query: 545 SRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSG 604
+ T SS + T TTS + T +S S + + + T+ SG
Sbjct: 149 TATNSDSSTTSSEASTATNSESSTTSSG--ASTATNSESSTVSSRASTATNSESSTTSSG 206
Query: 605 LSNSSDSLDSSTR---------PPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESH 655
S +++S +T S T G + A + P A GT T+SES
Sbjct: 207 ASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGA-----GTATNSESS 261
Query: 656 PEA-----APKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRD 710
+ A + S++ T N SE + P + A +SESS S ++ +
Sbjct: 262 TTSSGAGTATNSESSTVSSGISTVTN----SESSTPSSGANTATNSESSTTSSGANTATN 317
Query: 711 TDSDTQDANDSSCKSSERS 729
+DS T + S+ +SE S
Sbjct: 318 SDSSTTSSGASTATNSESS 336
Score = 33.1 bits (74), Expect = 1.3
Identities = 31/144 (21%), Positives = 59/144 (40%), Gaps = 7/144 (4%)
Query: 589 YLDSQDHKSEVTSQSGLSNSSDSLDSSTRP---PSVTRGGVAPAPEAPEPPPKHAALKSE 645
+L++ + +E ++ + +S S +ST SVT GV+ A + +
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 646 QGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSM 705
++ S A + S++ N + +G A +SESS PS
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGAST----ATNSESSTPSSGA 132
Query: 706 SSRRDTDSDTQDANDSSCKSSERS 729
S+ ++DS T + S+ +S+ S
Sbjct: 133 STATNSDSSTTSSGASTATNSDSS 156
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 42.0 bits (97), Expect = 0.003
Identities = 64/277 (23%), Positives = 106/277 (38%), Gaps = 33/277 (11%)
Query: 537 PSTGSLSNSRTLPSSSCLVAYKKTPPPVPPR---TTSKPFISVTVQSSTESAQDTYLDSQ 593
PST SL+ + S + ++ + +P PPR T S P S+++ ST T +
Sbjct: 197 PSTASLTKMDSTASITRTLS-RASPTGTPPRASPTGSPPRASLSMMPSTALLIRT--PPR 253
Query: 594 DHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSE 653
+ + S++ L+ DS S TR PS P+ +P P A+L T +
Sbjct: 254 ASPTGMLSRTSLTKM-DSTASITRTPS------RPSTASPTGTPSRASLSMTPSTASLMR 306
Query: 654 SHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMSSRRDTDS 713
P A+P LS + T+ + + P+A PS S S +S T S
Sbjct: 307 MLPRASPTGMLSRTSL---TKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPS 363
Query: 714 DTQDANDSSCKS----SERSLPDCTP-------HPNSISIDAGPRQAPKIAQIKRNLSYG 762
S S S + P TP P++ S+ P +A + R
Sbjct: 364 RASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSR----- 418
Query: 763 DNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRR 799
S +++++ P P + + +P + G R
Sbjct: 419 -TSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSR 454
Score = 31.6 bits (70), Expect = 3.8
Identities = 60/272 (22%), Positives = 110/272 (40%), Gaps = 41/272 (15%)
Query: 527 SVSLQSLSPPPSTGSLSN--SRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTES 584
+ S+ SL PS SL+ S +L + + +A K PP RT + P S+ + ST S
Sbjct: 61 TTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTAS 120
Query: 585 AQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP--PSVTRGGVAPAPEAPEPPPKHAAL 642
T S+ + S++ LS + + + T P S+TR P A+L
Sbjct: 121 L--TRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTR------------TPPRASL 166
Query: 643 KSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPS 702
T + + + P A+P G+ RT G P + S +S+ +
Sbjct: 167 TMTPSTASLTRTPPRASP------TGMPSRTSPTGM-------PSTASLTKMDSTASI-T 212
Query: 703 HSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYG 762
++S T + + + S + S+ T ++ I PR +P + +L+
Sbjct: 213 RTLSRASPTGTPPRASPTGSPPRASLSMMPST----ALLIRTPPRASPTGMLSRTSLTKM 268
Query: 763 DNS-----DPALEASSLPPPDPWLETSSSSPA 789
D++ P+ +++ P P + S +P+
Sbjct: 269 DSTASITRTPSRPSTASPTGTPSRASLSMTPS 300
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 41.6 bits (96), Expect = 0.004
Identities = 36/158 (22%), Positives = 67/158 (42%), Gaps = 4/158 (2%)
Query: 579 QSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD----SSTRPPSVTRGGVAPAPEAPE 634
Q +S D+ DS+++ S+ SQ+ SS+S SS S ++ V
Sbjct: 308 QPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN 367
Query: 635 PPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAP 694
P P + ++ ++ + +S E K S Q + + S + P++ +
Sbjct: 368 PDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENS 427
Query: 695 SSESSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPD 732
SS+ + SHS S+ ++ + +DS + S RS D
Sbjct: 428 SSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKED 465
>gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]
Length = 1909
Score = 41.6 bits (96), Expect = 0.004
Identities = 64/275 (23%), Positives = 108/275 (39%), Gaps = 45/275 (16%)
Query: 535 PPPSTGSLSNSRT---LPSSSCLVAYKKTPPPVPPRTTSK--PFISVTVQSSTESAQDTY 589
P PS ++ +R PSSS V P P R K P ++ Q
Sbjct: 1008 PMPSPEAVIQTRCPAHAPSSSFTVMALGPPKVSPKRGVPKTSPRQTLGTPQRDIGLQTPR 1067
Query: 590 LDSQDHKS-EVTSQSGLS--NSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQ 646
+ H+ E+TS +S DS++ PP + GV +P + + S
Sbjct: 1068 ISPSTHEPLEMTSSKSVSPGRKGQLNDSASTPPKPSFLGVNESPSSQ--------VSSSS 1119
Query: 647 GTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMAPSSESSVPSHSMS 706
+ + ++SH + G++ R P + V+ S + S ++
Sbjct: 1120 SSSSPAKSHNSPHGCQSAHEKGLKTRL------------PVGLKVLMKSPQLLRKSSTVP 1167
Query: 707 SRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSD 766
+ + DS +A+ SS + +S P+ + +P S+ I AG +RN++ D+
Sbjct: 1168 GKHEKDS-LNEASKSSV-AVNKSKPEDSKNPASMEITAG----------ERNVTLPDSQA 1215
Query: 767 PALEASSLPPPDPWLETSSSSPAEPAQPGACRRDG 801
A LP LET+ P E + PG+ RDG
Sbjct: 1216 QGSLADGLP-----LETALQEPLESSIPGSDGRDG 1245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,386,431
Number of Sequences: 37866
Number of extensions: 2549915
Number of successful extensions: 21782
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 676
Number of HSP's that attempted gapping in prelim test: 17631
Number of HSP's gapped (non-prelim): 4628
length of query: 989
length of database: 18,247,518
effective HSP length: 112
effective length of query: 877
effective length of database: 14,006,526
effective search space: 12283723302
effective search space used: 12283723302
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.