Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 34335251

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34335251 disks large-associated protein 4 isoform b [Homo
sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34335251 disks large-associated protein 4 isoform b [Homo sap...   911   0.0  
gi|34335253 disks large-associated protein 4 isoform a [Homo sap...   813   0.0  
gi|109891938 disks large-associated protein 4 isoform c [Homo sa...   577   e-164
gi|19923274 discs large homolog-associated protein 1 isoform alp...   425   e-119
gi|51339031 discs large homolog-associated protein 1 isoform bet...   425   e-119
gi|38202224 discs large-associated protein 2 [Homo sapiens]           393   e-109
gi|122937233 discs, large (Drosophila) homolog-associated protei...   311   1e-84
gi|226371669 discs large homolog 7 isoform b [Homo sapiens]            83   4e-16
gi|226371667 discs large homolog 7 isoform a [Homo sapiens]            83   4e-16
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        48   2e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    45   1e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         43   5e-04
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    43   7e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    42   9e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    42   0.001
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  41   0.002
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   41   0.003
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   41   0.003
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   41   0.003
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    41   0.003
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    41   0.003
gi|82830424 gon-4-like isoform a [Homo sapiens]                        40   0.004
gi|47132519 Ras association and pleckstrin homology domains 1 is...    40   0.006
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       40   0.006
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    39   0.007
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       39   0.007
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        39   0.007
gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo s...    39   0.007
gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo s...    39   0.007
gi|146134388 YLP motif containing 1 [Homo sapiens]                     39   0.007

>gi|34335251 disks large-associated protein 4 isoform b [Homo
           sapiens]
          Length = 453

 Score =  911 bits (2354), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MALCLELLKQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEV 60
           MALCLELLKQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEV
Sbjct: 1   MALCLELLKQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEV 60

Query: 61  TSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA 120
           TSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA
Sbjct: 61  TSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA 120

Query: 121 PKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQ 180
           PKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQ
Sbjct: 121 PKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQ 180

Query: 181 DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 240
           DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP
Sbjct: 181 DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 240

Query: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300
           PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL
Sbjct: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300

Query: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360
           GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF
Sbjct: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360

Query: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420
           DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR
Sbjct: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420

Query: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453
           LLAAKRAASVRQNSATESADSIEIYVPEAQTRL
Sbjct: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453


>gi|34335253 disks large-associated protein 4 isoform a [Homo
           sapiens]
          Length = 989

 Score =  813 bits (2099), Expect = 0.0
 Identities = 416/444 (93%), Positives = 420/444 (94%), Gaps = 7/444 (1%)

Query: 12  SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71
           SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD
Sbjct: 551 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 610

Query: 72  SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ 131
           SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ
Sbjct: 611 SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ 670

Query: 132 VDCIQPVP--KEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189
               +      E+  P    ++I V       SSVPSHSMSSRRDTDSDTQDANDSSCKS
Sbjct: 671 ERTRRNGSHLSEDNGP----KAIDVMAPSS-ESSVPSHSMSSRRDTDSDTQDANDSSCKS 725

Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249
           SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS
Sbjct: 726 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 785

Query: 250 SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS 309
           SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS
Sbjct: 786 SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS 845

Query: 310 AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN 369
           AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN
Sbjct: 846 AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN 905

Query: 370 SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS 429
           SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS
Sbjct: 906 SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS 965

Query: 430 VRQNSATESADSIEIYVPEAQTRL 453
           VRQNSATESADSIEIYVPEAQTRL
Sbjct: 966 VRQNSATESADSIEIYVPEAQTRL 989


>gi|109891938 disks large-associated protein 4 isoform c [Homo
           sapiens]
          Length = 285

 Score =  577 bits (1486), Expect = e-164
 Identities = 285/285 (100%), Positives = 285/285 (100%)

Query: 169 MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN 228
           MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN
Sbjct: 1   MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN 60

Query: 229 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK 288
           SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK
Sbjct: 61  SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK 120

Query: 289 ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL 348
           ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL
Sbjct: 121 ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL 180

Query: 349 LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD 408
           LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD
Sbjct: 181 LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD 240

Query: 409 ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453
           ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL
Sbjct: 241 ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 285


>gi|19923274 discs large homolog-associated protein 1 isoform alpha
           [Homo sapiens]
          Length = 977

 Score =  425 bits (1092), Expect = e-119
 Identities = 231/453 (50%), Positives = 306/453 (67%), Gaps = 18/453 (3%)

Query: 12  SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71
           SSC+  YKKTPPPVPPRTT+KPFIS+T QSSTESAQD Y+D Q  + ++ SQSGLSNS++
Sbjct: 532 SSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTE 591

Query: 72  SLDSSTRPPSVTRGGVA----PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSS 127
           SLDS     +      A    PA +            +   T+T+ +   +   K +  S
Sbjct: 592 SLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLS 651

Query: 128 IGIQVD-CIQPVPKEEPSPATKFQSIGVQVEDD--WRSSVPSHSMSSRRDTDSDTQDAND 184
           IGIQVD   +P    E    +KFQS+GVQVE++  +R    S+S+++    D D  D  +
Sbjct: 652 IGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLE 711

Query: 185 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYG----DNSDPALEASSLPP 240
           +S +S E    +  P P +         +    Q   N  +     D+ D   + S LPP
Sbjct: 712 NSLESIE---DNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPP 768

Query: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300
           PDPW+++ +  P E  Q   C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++L
Sbjct: 769 PDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDIL 828

Query: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360
           GK+ +AVGSAQLLM+QKF QFR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKF
Sbjct: 829 GKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKF 888

Query: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420
           DEL+ LKAN+W+ ++  +K+  E++ PPPVPKKPAK    + R+++ ++S  QRQEARKR
Sbjct: 889 DELHQLKANNWKQMDPLDKK--ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKR 944

Query: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453
           L+AAKRAASVRQNSATESA+SIEIY+PEAQTRL
Sbjct: 945 LMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977


>gi|51339031 discs large homolog-associated protein 1 isoform beta
           [Homo sapiens]
          Length = 675

 Score =  425 bits (1092), Expect = e-119
 Identities = 231/453 (50%), Positives = 306/453 (67%), Gaps = 18/453 (3%)

Query: 12  SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71
           SSC+  YKKTPPPVPPRTT+KPFIS+T QSSTESAQD Y+D Q  + ++ SQSGLSNS++
Sbjct: 230 SSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTE 289

Query: 72  SLDSSTRPPSVTRGGVA----PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSS 127
           SLDS     +      A    PA +            +   T+T+ +   +   K +  S
Sbjct: 290 SLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLS 349

Query: 128 IGIQVD-CIQPVPKEEPSPATKFQSIGVQVEDD--WRSSVPSHSMSSRRDTDSDTQDAND 184
           IGIQVD   +P    E    +KFQS+GVQVE++  +R    S+S+++    D D  D  +
Sbjct: 350 IGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLE 409

Query: 185 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYG----DNSDPALEASSLPP 240
           +S +S E    +  P P +         +    Q   N  +     D+ D   + S LPP
Sbjct: 410 NSLESIE---DNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPP 466

Query: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300
           PDPW+++ +  P E  Q   C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++L
Sbjct: 467 PDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDIL 526

Query: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360
           GK+ +AVGSAQLLM+QKF QFR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKF
Sbjct: 527 GKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKF 586

Query: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420
           DEL+ LKAN+W+ ++  +K+  E++ PPPVPKKPAK    + R+++ ++S  QRQEARKR
Sbjct: 587 DELHQLKANNWKQMDPLDKK--ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKR 642

Query: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453
           L+AAKRAASVRQNSATESA+SIEIY+PEAQTRL
Sbjct: 643 LMAAKRAASVRQNSATESAESIEIYIPEAQTRL 675


>gi|38202224 discs large-associated protein 2 [Homo sapiens]
          Length = 975

 Score =  393 bits (1010), Expect = e-109
 Identities = 226/462 (48%), Positives = 295/462 (63%), Gaps = 42/462 (9%)

Query: 18  YKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS--GLSNSSDSLDS 75
           YKKTPPPVPPRTTSKP ISVT QSSTES QD Y DS+  +     Q   GL NS+DSLDS
Sbjct: 530 YKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDS 589

Query: 76  STRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCI 135
           +    ++       A +   P  + +++++    +  S++  E   K + SSIGIQ    
Sbjct: 590 NK---AMNLALETAAAQRHLPESQSSSVRTSDKAILVSKA--EELLKSRCSSIGIQDSEF 644

Query: 136 ---QPVPKEEPSPAT----------KFQSIGVQVEDDWRSSVPSHSMSSRRDTDSD---- 178
              QP P+ +   AT          ++ S+GVQVED+ R      S S      +D    
Sbjct: 645 PEHQPYPRSDVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELE 704

Query: 179 -------TQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDP 231
                  T+D       S +R     TP   S         A +  + +   SY ++   
Sbjct: 705 GFPGHITTEDKGLQFGSSFQRHSEPSTPTQYS---------AVRTVRTQGLFSYREDYRT 755

Query: 232 ALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETK 291
            ++ S+LPPPDPWLE +  +  E  +   CRRDG WFLKLL AET+R+EGWC +M++E +
Sbjct: 756 QVDTSTLPPPDPWLEPAIDT-VETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAE 814

Query: 292 ENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQL 351
           EN+LSEE+LGK+ SAVGSAQLLMSQKFQQF  LC+QN++P A PRPT+QDLAG+WD+LQL
Sbjct: 815 ENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQL 874

Query: 352 SIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASD 411
           SIED+SMKFDEL  L+ N W+++E+PE RKEE+K PPP+PKKP K K  ++R+K+ D  D
Sbjct: 875 SIEDVSMKFDELQRLRLNDWKMMESPE-RKEERKVPPPIPKKPPKGKFPITREKSLDLPD 933

Query: 412 KQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453
           +QRQEAR+RL+AAKRAAS RQNSA+E ADSIEIY+PEAQTRL
Sbjct: 934 RQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975


>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
           [Homo sapiens]
          Length = 979

 Score =  311 bits (796), Expect = 1e-84
 Identities = 193/466 (41%), Positives = 261/466 (56%), Gaps = 53/466 (11%)

Query: 18  YKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSST 77
           ++K PPP+PP + + P IS+T QSST+SA +++          T+  G +    S D   
Sbjct: 537 FRKAPPPIPPGSQAPPRISITAQSSTDSAHESF----------TAAEGPARRCSSADGLD 586

Query: 78  RPPSVTRG-GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQ 136
            P    R   +AP P    P P    +K+  G     E    A  ++   SIG+QV+ I 
Sbjct: 587 GPAMGARTLELAPVPPRASPKPPTLIIKTIPGR---EELRSLARQRKWRPSIGVQVETIS 643

Query: 137 PVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSD-------------TQDAN 183
               E  S   +F SIGVQVE+D R +    S S      +D             T+D  
Sbjct: 644 DSDTENRS-RREFHSIGVQVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKA 702

Query: 184 DSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN-----SDPALEASSL 238
               +S +R   +  P P + +         +    +   +Y +        PA + S  
Sbjct: 703 LQFGRSFQRHASEPQPGPRAPTYSVF-----RTVHTQGQWAYREGYPLPYEPPATDGSPG 757

Query: 239 PPPDP-----------WLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMD 287
           P P P           W+E  S S  +  +   C RDG WF+K+L+AE E+LE WC QM+
Sbjct: 758 PAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQME 817

Query: 288 KETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWD 347
           +E ++  L EE+L K+ SAVGS QLL+SQK QQF  LC+Q+++P A P PT QDLAGFWD
Sbjct: 818 REAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWD 877

Query: 348 LLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKAS 407
           LLQLSIED+++KF EL  LKANSW+L+E     KEEKK PPP+PKKP + +    ++++ 
Sbjct: 878 LLQLSIEDVTLKFLELQQLKANSWKLLEP----KEEKKVPPPIPKKPLRGRGVPVKERSL 933

Query: 408 DASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453
           D+ D+QRQEARKRLLAAKRAAS R +SATESADSIEIY+PEAQTRL
Sbjct: 934 DSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979


>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
          Length = 842

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%)

Query: 267 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 326
           +F  +LQ+ETE+L   C + D++  E ++ ++    + +AVG  +LLM ++F+QF GL +
Sbjct: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490

Query: 327 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 386
                      T  DL GFWD++   IED+  KF+ L  L+ + WQ+         +   
Sbjct: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548

Query: 387 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 442
              V +K   S  A S+ K  DA    R  AR RL A K A    +RQ    E+A S+
Sbjct: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599


>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
          Length = 846

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%)

Query: 267 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 326
           +F  +LQ+ETE+L   C + D++  E ++ ++    + +AVG  +LLM ++F+QF GL +
Sbjct: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490

Query: 327 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 386
                      T  DL GFWD++   IED+  KF+ L  L+ + WQ+         +   
Sbjct: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548

Query: 387 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 442
              V +K   S  A S+ K  DA    R  AR RL A K A    +RQ    E+A S+
Sbjct: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 59/242 (24%), Positives = 86/242 (35%), Gaps = 38/242 (15%)

Query: 23   PPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSV 82
            P VP     +P  S   Q    SA      +++ +S  +S S  S+SS S  SS+   S 
Sbjct: 2499 PGVPHSDVGEPPASTGAQQP--SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS- 2555

Query: 83   TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEE 142
                              +   S     +S    PE A KR  S      + ++     E
Sbjct: 2556 ------------------SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597

Query: 143  PSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPN 202
            P+PA + +           SS  S S SS   + S +  ++ SS  SS  S     P P 
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657

Query: 203  SISIDAGPRQAP-------------KIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249
            ++   A P++ P                +  R+LSY     P       P P P  + SS
Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY----SPVERRRPSPQPSPRDQQSS 2713

Query: 250  SS 251
            SS
Sbjct: 2714 SS 2715



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 43/188 (22%), Positives = 69/188 (36%), Gaps = 19/188 (10%)

Query: 55   DHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGT----- 109
            D KS ++ +   S SS  +    R     + G   +PE   P P+    +S  G+     
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645

Query: 110  ------LTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSS 163
                   +S+ES PE  PK + +  G +    +P  K    P  +      ++    R S
Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSR-SSPEPKTKSRTPPRRRSSRSSPELTRKARLS 1704

Query: 164  VPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNL 223
              S S SS  +T S T   +        RS    +P P   S  +  R++    + K   
Sbjct: 1705 RRSRSASSSPETRSRTPPRH-------RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757

Query: 224  SYGDNSDP 231
              G +  P
Sbjct: 1758 RRGRSPSP 1765



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 67/267 (25%), Positives = 97/267 (36%), Gaps = 40/267 (14%)

Query: 17   AYKKTPPPVPP--RTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD 74
            A  +TPP  P   R TS+   S + +     +Q     +QD        S  S+ S  L 
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVP-SAFSDQSRCLI 2463

Query: 75   SSTRP----PSVTRGGVAPAPEAPEPPPKHAALKS--EQGTLTSSESHPEAAPKRKLSSI 128
            + T P     S++ G VA    +      H  + S    G   S    P A       S 
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGD---HNGMLSVPAPGVPHSDVGEPPA-------ST 2513

Query: 129  GIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSC- 187
            G Q    QP       PA + +S          SS  S S SS   + S + D+  SS  
Sbjct: 2514 GAQ----QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569

Query: 188  ---KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPW 244
               + + + +P  TP P     +  P + P  A+ KR  S   +S  +  +SS       
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPE-PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628

Query: 245  LETSSSSPAE------------PAQPG 259
              +SSSS +             PA+PG
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPG 2655



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 43/176 (24%), Positives = 64/176 (36%), Gaps = 27/176 (15%)

Query: 57  KSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESH 116
           KS+   +   S SS     S  PP  +R        +  PPPK      ++    S +SH
Sbjct: 789 KSQTPPRRSRSGSSQPKAKSRTPPRRSRS-------SSSPPPK------QKSKTPSRQSH 835

Query: 117 PEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD 176
             ++P  K+ S         P      SP    QS+  Q    + SS P   + SR  + 
Sbjct: 836 SSSSPHPKVKS------GTPPRQGSITSPQANEQSVTPQRRSCFESS-PDPELKSRTPSR 888

Query: 177 SDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPA 232
                ++    KSS       TP   S S  + P+   K     R  S+  +S P+
Sbjct: 889 HSCSGSSPPRVKSS-------TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937



 Score = 32.3 bits (72), Expect = 0.91
 Identities = 22/77 (28%), Positives = 34/77 (44%)

Query: 33   PFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPE 92
            P + +  QS+  S   +   S D   +    S  S SS  LD+  R PS  R   A +PE
Sbjct: 1367 PSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426

Query: 93   APEPPPKHAALKSEQGT 109
              +  P+  + +S  G+
Sbjct: 1427 MKDGLPRTPSRRSRSGS 1443



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 50/216 (23%), Positives = 77/216 (35%), Gaps = 13/216 (6%)

Query: 56  HKSEVTSQSGLSNSSDSLDSSTRPPSVTRG--GVAPAPEAPEPPPKHAALKSEQGTLTSS 113
           H+S     +  S++S S   S    + T    G +P+P +       A       T T  
Sbjct: 261 HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320

Query: 114 ESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSR- 172
            S PE A K+  S    +    +      PSP+ +  S G +           H  S + 
Sbjct: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQP 380

Query: 173 -RDTDSDTQDANDSSCKSSERS-LPDCTPH--PNSISIDAGPRQAPKIAQIKRNLSYGDN 228
              T    +  N  S  S  R   P  +P   P S S ++ P  +P+  ++ R+ S    
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSP-PSPQPTKVSRHASSSPE 439

Query: 229 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264
           S         P P    E SSS  ++    G  +RD
Sbjct: 440 S-----PKPAPAPGSHREISSSPTSKNRSHGRAKRD 470



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 48/219 (21%), Positives = 82/219 (37%), Gaps = 39/219 (17%)

Query: 75  SSTRPPSVTRGGVAPAPEAPE-------------PPPKHAALKSEQGTLTSSESHPEAAP 121
           SS  P    R    PAPE P+             P PK    K ++     SES      
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208

Query: 122 KRKLSSIGIQVDCIQPVPKE--EPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDT 179
           ++K S         +   ++   P+P +K +S   + +    ++    S  + R T +D+
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268

Query: 180 QDANDSS--------CKSSERSLPDCTPHPNSISIDAGPR-------------QAPKIAQ 218
             ++D+S         K+   +L   +P P S     G                +P+ A 
Sbjct: 269 ASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT 328

Query: 219 IKRNLSYGD-NSDPALEASSLPPPDPWLETSSSSPAEPA 256
            + +  Y D + D   ++++ P P P  E SS+ P  PA
Sbjct: 329 KQPSSPYEDKDKDKKEKSATRPSPSP--ERSSTGPEPPA 365



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 14/65 (21%), Positives = 30/65 (46%)

Query: 377  PEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSAT 436
            P++   E +PP P P K  +   + S   +S +S      +     ++  ++S   +S++
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645

Query: 437  ESADS 441
             S+ S
Sbjct: 2646 SSSPS 2650


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 85/448 (18%), Positives = 160/448 (35%), Gaps = 48/448 (10%)

Query: 26  PPRTTSKPFISVTVQSSTESAQDTYLDSQD--HKSEVTSQSGLSNSSDSLDSSTRPPSVT 83
           PP+        VTV++ T++       +    +    +S S  S+SS S DS     + T
Sbjct: 179 PPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAAT 238

Query: 84  RGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEP 143
                P  +     P  AA    + + +S +S  +   ++K              P   P
Sbjct: 239 PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAP 298

Query: 144 SPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNS 203
            P    +S+G Q         P  ++  ++  +S    +++S   S E   P     P  
Sbjct: 299 PPK---KSLGTQP--------PKKAVEKQQPVESSEDSSDESDSSSEEEKKP-----PTK 342

Query: 204 ISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPA----EPA-QP 258
             +     + P   +   + S   +SD + +  +   P    + SS+ PA     PA +P
Sbjct: 343 AVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKP 402

Query: 259 GACRRD---GYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMS 315
            A  +    G   L   +A++   E    +    ++E    + V      A   A L + 
Sbjct: 403 AAAPKQPVGGGQKLLTRKADSSSSE----EESSSSEEEKTKKMVATTKPKATAKAALSLP 458

Query: 316 QKFQQFRGLCEQNLNPDANP-------------RPTAQDLAGFWDLLQLSIEDISMKFDE 362
            K Q  +G  + + + D++              +   Q +AG                 E
Sbjct: 459 AK-QAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAG--GAAPSKPASAKKGKAE 515

Query: 363 LYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLL 422
             +  ++     E  EK K +  P P  PK    S       KA+  S+++ +E +K  +
Sbjct: 516 SSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAV 575

Query: 423 AAKRAASVRQNSATESADSIEIYVPEAQ 450
              ++ S+++    E+A   E   P+A+
Sbjct: 576 VVSKSGSLKKRKQNEAAKEAE--TPQAK 601



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 50/241 (20%), Positives = 87/241 (36%), Gaps = 40/241 (16%)

Query: 58  SEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHP 117
           ++ +  S    SSD  D   +     + GV P  +A + PPK A   S+  + +SSE  P
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK-SSDSDSDSSSEDEP 179

Query: 118 EAAPKRKLSSIGIQVDCIQP------VPK-----------------------EEPSPATK 148
               K K++ + ++     P       PK                       EE + AT 
Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239

Query: 149 FQSIG----VQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS-----SERSLPDCTP 199
            +++     V       ++ P+   SS  D+ SD ++      K+     S    P   P
Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP 299

Query: 200 HPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPG 259
              S+      +   K   ++ +    D SD + E    PP    +  +++ P  PA+  
Sbjct: 300 PKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP-PPAKKA 358

Query: 260 A 260
           A
Sbjct: 359 A 359



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 37/196 (18%)

Query: 67  SNSSDSLDSSTRPPSV----TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK 122
           ++SSDS DSS     V     +    PA     PP K AA  SE  +   S    +   +
Sbjct: 82  ASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQ 141

Query: 123 RKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDA 182
           +K           QPV K            GV+ +     + P  + SS  D+DS ++D 
Sbjct: 142 KK-----------QPVQK------------GVKPQAKAAKAPPKKAKSSDSDSDSSSEDE 178

Query: 183 NDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPD 242
              + K      P  TP    +++ A  +  PK A+    ++ G  +  +  +SS    D
Sbjct: 179 PPKNQK------PKITP----VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSD 228

Query: 243 PWLETSSSSPAEPAQP 258
              E  +++  +   P
Sbjct: 229 DSEEEKAAATPKKTVP 244



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 57/253 (22%), Positives = 89/253 (35%), Gaps = 48/253 (18%)

Query: 18  YKKTPPPV--PPRT---TSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDS 72
           Y   PPP   PP+    T  P  +V  Q   ES++D                    SSD 
Sbjct: 289 YSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSED--------------------SSDE 328

Query: 73  LDSST----RPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSI 128
            DSS+    +PP  T+  V+ A    +PPP   A +S   +  S  S  + AP +   + 
Sbjct: 329 SDSSSEEEKKPP--TKAVVSKA--TTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGT- 383

Query: 129 GIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCK 188
                           PA   +S  V+     +  V        R  DS + +   SS +
Sbjct: 384 ---------TKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSE 434

Query: 189 SSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALE-----ASSLPPPDP 243
             +      T  P + +  A    A +  Q  R+ S   +S  + E     + S     P
Sbjct: 435 EEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKP 494

Query: 244 WLETSSSSPAEPA 256
                 ++P++PA
Sbjct: 495 QKVAGGAAPSKPA 507



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 31/135 (22%)

Query: 19  KKTPPPVPPRTTSKPFISVTV----QSSTESAQDTYLDSQDHKSEVTSQSGL-------- 66
           KK      P+ T+K  +S+      Q S +S+ D+   S + + E TS+S +        
Sbjct: 439 KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVA 498

Query: 67  ------------------SNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQG 108
                             SNSS S DSS       +G  +P P+AP+     +AL ++ G
Sbjct: 499 GGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT-SALTAQNG 557

Query: 109 TLTSSESHPEAAPKR 123
               +    E   K+
Sbjct: 558 KAAKNSEEEEEEKKK 572


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 55/223 (24%), Positives = 82/223 (36%), Gaps = 18/223 (8%)

Query: 42   STESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHA 101
            S + AQ     +++ +S  +S SG S+SS S  SS         G            ++ 
Sbjct: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNC 2602

Query: 102  ALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWR 161
            +  S +    +S S   ++     SS                S ++   S          
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSS--------SSSSSSSSSSSSSSSSSSSSSS 2654

Query: 162  SSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKR 221
            SS  S S SS   + S T D  DSSC S + + P  T  P++ +  A P +A K A   R
Sbjct: 2655 SSSSSSSSSSSSSSSSSTTD-EDSSCSSDDEAAPAPTAGPSAQA--ALPTKATKQAGKAR 2711

Query: 222  NLSYGDNSDPALEASSLPPPDPWLETSSSSPAEP-AQPGACRR 263
              ++             PPP P      + P +P AQ GA  R
Sbjct: 2712 PSAHSPGKKTPAPQPQAPPPQP------TQPLQPKAQAGAKSR 2748



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 2/116 (1%)

Query: 29   TTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVA 88
            ++S    S +  SS+ S+  +   S    S  +S S  S+SS S  S+T   S       
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684

Query: 89   PAPEAPEPPPKHAALKSEQGTLTSSESHPEA-APKRKLSSIGIQVDCIQPVPKEEP 143
             AP     P   AAL + + T  + ++ P A +P +K  +   Q    QP    +P
Sbjct: 2685 AAPAPTAGPSAQAALPT-KATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQP 2739


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 53/217 (24%), Positives = 75/217 (34%), Gaps = 13/217 (5%)

Query: 22  PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81
           PPP PPR +SK   +      +   Q          +  TS    S+SS S     +  S
Sbjct: 275 PPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKS 334

Query: 82  VTRGGVAPAPEAPEPPPKHAALK---SEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPV 138
            TRG    A   P    K   ++   SE      SES   +      SS        +P 
Sbjct: 335 STRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPS 394

Query: 139 PKEEPSPATKF----QSIGVQVEDDWRSSVPSHSMSSRRDT-----DSDTQDANDSSCKS 189
                 P        QS     +D       +   +  RD+     DS++ ++ DSS  S
Sbjct: 395 QNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPS 454

Query: 190 SERSLPDCTPHPNS-ISIDAGPRQAPKIAQIKRNLSY 225
            E   P   P PNS +S    P    K  +I +  +Y
Sbjct: 455 REPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTY 491



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 53/242 (21%), Positives = 88/242 (36%), Gaps = 29/242 (11%)

Query: 27  PRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD----SSTRPPSV 82
           P+ T     S      +      +  +++H+      S   +SS  L+     S++  S 
Sbjct: 172 PKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSR 231

Query: 83  TRGGVAPAPEAPEPPPKHA------ALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQ 136
             G      E   PPPK A      ALK  +   TS +  P   P         +    +
Sbjct: 232 KLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPP-----RASSKR 286

Query: 137 PVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPD 196
           P   + P P+ K Q      +   + S  +   S R  + S   D   +  KSS R    
Sbjct: 287 PATADSPKPSAKKQK-----KSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRG--- 338

Query: 197 CTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP-PDPWLETSSSSPAEP 255
                  +  ++ PR+A K  +++ + S  + S  +  A S P       ++SS S  EP
Sbjct: 339 -----EKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEP 393

Query: 256 AQ 257
           +Q
Sbjct: 394 SQ 395



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 386 PPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESAD 440
           PPPP P   A SK   + D    ++ KQ++ + K   +A    S R +S++  +D
Sbjct: 273 PPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAP-GTSPRTSSSSSFSD 326


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 47/215 (21%), Positives = 80/215 (37%), Gaps = 3/215 (1%)

Query: 41  SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
           SS   +  +  +S    S+  S S  SNSSDS D+S    S      + + ++ +     
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678

Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
           ++  S   + +S  S    + +   SS     D          + +    S      D  
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738

Query: 161 RSSVPSHSMSSRRDTD-SDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQI 219
            SS  S S  S   +D SD+ D+++SS  S      D +   N  S D+        +  
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN--SSDSNDSSNSSDSSD 796

Query: 220 KRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAE 254
             N S   NS  + ++S     D    + SS+ ++
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 45/213 (21%), Positives = 78/213 (36%)

Query: 42  STESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHA 101
           S++S+     DS D  +  +S S  SNSSDS DSS    S      + + ++ +      
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 102 ALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWR 161
           +  S   + +S  S    +     SS                S  +   S     +    
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 162 SSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKR 221
           S   + S SS     SD+ D++DSS  S   S        +S S D+        +    
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883

Query: 222 NLSYGDNSDPALEASSLPPPDPWLETSSSSPAE 254
           + +   NS  + ++S+    D    ++SS  ++
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916



 Score = 36.6 bits (83), Expect = 0.048
 Identities = 46/211 (21%), Positives = 76/211 (36%), Gaps = 2/211 (0%)

Query: 41  SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
           SS  S      DS D  S+ +  S  SNSSDS DSS    S      + +  + +     
Sbjct: 755 SSDSSDSSNSSDSSD-SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813

Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
            +  S+    + S +  +++     S      D       +  + +    S       D 
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873

Query: 161 RSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIK 220
            +S  S S SS  +  S++ D++DSS  S   S        +S S ++        +   
Sbjct: 874 SNSSDS-SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932

Query: 221 RNLSYGDNSDPALEASSLPPPDPWLETSSSS 251
            N S   NS  + ++S          +S SS
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963



 Score = 36.6 bits (83), Expect = 0.048
 Identities = 34/164 (20%), Positives = 64/164 (39%), Gaps = 2/164 (1%)

Query: 42   STESAQDTYLDSQD--HKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPK 99
            S++S+  +  DS D  + S+ +  S  S+SS+S +SS    S      + + ++ +    
Sbjct: 894  SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953

Query: 100  HAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDD 159
              +  S   + +S  S   ++     S+     D        + S ++         +  
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 160  WRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNS 203
              S+    S SS     SD+ D++DSS  S      D +   NS
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057



 Score = 36.2 bits (82), Expect = 0.063
 Identities = 43/224 (19%), Positives = 80/224 (35%), Gaps = 6/224 (2%)

Query: 41   SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
            S++  + D+   S    S+ +++S  SNSSDS DSS    S      + + E+       
Sbjct: 836  SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895

Query: 101  AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
             +  S     + S +  +++     S      D  +     + S ++   +     +   
Sbjct: 896  DSSNSSDSDSSDSSNSSDSSDSSNSS------DSSESSNSSDNSNSSDSSNSSDSSDSSD 949

Query: 161  RSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIK 220
             S+    S SS     SD+ D+N S    S  S        +S S D+        +   
Sbjct: 950  SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009

Query: 221  RNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264
             + S   NS  +  +S         ++S SS +  +   +   D
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 52/229 (22%), Positives = 81/229 (35%), Gaps = 7/229 (3%)

Query: 41   SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
            SS  S      DS D  S  +S S  SNSSDS DSS    S      + + ++ +     
Sbjct: 956  SSNSSDSSNSSDSSDSNSSDSSDS--SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 101  AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
             +  S   + +S  S+   +     SS                S  +   S      D  
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073

Query: 161  RSSVPSHSMSSRRDTD----SDTQDANDSSCKSSERSLPDCTPHPNSI-SIDAGPRQAPK 215
             SS  S S  S   +D    SD+ D++DSS  S      D +   +S  S D+       
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133

Query: 216  IAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264
             +    N S   +S  + ++S         ++S SS +  +   +   D
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 43/169 (25%), Positives = 61/169 (36%), Gaps = 5/169 (2%)

Query: 41   SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
            SS  S      DS D  S+ +  S  SNSSDS DSS    S      + + ++ E     
Sbjct: 1096 SSDSSDSSDSSDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154

Query: 101  AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
             +  S   + +S  S    +     SS                S  +   S      D  
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214

Query: 161  RSSVPSHSMSSRRDTDS----DTQDANDSSCKSSERSLPDCTPHPNSIS 205
             SS  S S  S   +DS    D+ D++DSS  S+     D +   +S S
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 49/221 (22%), Positives = 79/221 (35%), Gaps = 8/221 (3%)

Query: 41  SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
           SS  S      DS D  S+ +S S  SNSSDS DSS    S      + + ++       
Sbjct: 659 SSNSSNSSDSSDSSD-SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717

Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
           ++  +   + +S+ S    +     SS                S  +   S      D  
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 161 RSSVPSHSMSSRRDTDS-------DTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQA 213
            SS  S S  S   +DS       D+ +++DSS  S            +S S D+     
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 214 PKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAE 254
              +    + S G +SD +  + S    D    + SS+ ++
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 42/167 (25%), Positives = 59/167 (35%), Gaps = 5/167 (2%)

Query: 41   SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
            SS  S      DS D  S+ +  S  SNSSDS DSS    S      + + ++ E     
Sbjct: 1030 SSDSSDSSDSSDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088

Query: 101  AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
             +  S   + +S  S    +     SS                S  +   S      D  
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148

Query: 161  RSSVPSHSMSSRRDTDS----DTQDANDSSCKSSERSLPDCTPHPNS 203
             SS  S S  S   +DS    D+ D++DSS  S      D +   +S
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 47/226 (20%), Positives = 84/226 (37%), Gaps = 14/226 (6%)

Query: 41   SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
            +S++S+  +      + S+ ++ S  SNSSDS DSS    S      + + ++       
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061

Query: 101  AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
             +  S   + +S  S    + +   SS                S  +   S      D  
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSS------------DSSNSSDSSDSSDSSDSSDSS 1109

Query: 161  RSSVPSHSMSSRRDTD-SDTQDANDSSCKSSERSLPDCTPHPNSI-SIDAGPRQAPKIAQ 218
             SS  S S  S   +D SD+ D++DSS  S+     D +   +S  S D+        + 
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169

Query: 219  IKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264
               + S   NS  + ++S         ++S SS +  +   +   D
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215



 Score = 33.1 bits (74), Expect = 0.53
 Identities = 35/157 (22%), Positives = 58/157 (36%), Gaps = 5/157 (3%)

Query: 41   SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
            SS  S      DS D  S+ +  S  SNSSDS DSS    S      + + ++ +     
Sbjct: 1114 SSDSSDSSNSSDSSD-SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172

Query: 101  ----AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQV 156
                ++  S+    + S    +++     S      D        + S ++         
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232

Query: 157  EDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERS 193
            E    S     S SS     SD+ D++DS+  S++ S
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 37/150 (24%), Positives = 56/150 (37%), Gaps = 7/150 (4%)

Query: 41   SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
            SS  S      DS D  SE +  S  S+SSDS DSS    S      + + ++ +     
Sbjct: 1132 SSDSSDSSNSSDSSD-SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190

Query: 101  AALKSEQGTLTSSESHP-EAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDD 159
             +  S   + +S  S   +++     S      D        E S ++           D
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD-----SSD 1245

Query: 160  WRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189
              +S  S   S   D+ SD+ D +DS  KS
Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 44/212 (20%), Positives = 71/212 (33%), Gaps = 2/212 (0%)

Query: 41  SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100
           S ++ A+D   DS    +   S    +N +D  D S      +    + + ++       
Sbjct: 505 SDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSS 564

Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160
            +  S+     SS     +      SS     D        + S ++   S      D  
Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD-SSDSSDSSDSK 623

Query: 161 RSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIK 220
             S  S S SS  D+ SD+ D+N S    +  S        +S S D+        +   
Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS 683

Query: 221 RNLS-YGDNSDPALEASSLPPPDPWLETSSSS 251
            N S   D+SD +  + S    D     SS S
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 40/136 (29%), Positives = 57/136 (41%), Gaps = 11/136 (8%)

Query: 22   PPP-----VPPRTT-SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDS 75
            PPP     +PPR+  S PF  V     ++S+  + L  +   +E    S ++    S D 
Sbjct: 2390 PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449

Query: 76   STRPPS--VTRGGVAPAPEAPEPPPKHAALKSEQGTLTS--SESHPEAAPKRKLSSIGIQ 131
             +RPPS   +R   AP  + P P P   A K+     TS  +   P A P      +  +
Sbjct: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK 2509

Query: 132  VDCIQPVPKEEPSPAT 147
            V   QP P    SP T
Sbjct: 2510 VPSGQP-PNFVRSPGT 2524



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 65/287 (22%), Positives = 99/287 (34%), Gaps = 58/287 (20%)

Query: 21  TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSN-SSDSLDSSTRP 79
           +PPP   R +  P +S       ES     L     +S  +     S  S    DS T P
Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEESP----LSPPPEESPTSPPPEASRLSPPPEDSPTSP 700

Query: 80  PS-----------------VTRGGVAPAPEAPEPPPK----HAALKSEQGTLTSSESHPE 118
           P                  +    + P PE P+  P+    H + + E+  L+     P 
Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPH 760

Query: 119 AAPKRKLSSIGIQVD--CIQPVPKEEP-----------SPATKFQSIGVQVEDDWRSSVP 165
            +P+ +   +  Q +  C+  VP EEP           SP  +   +  Q E+   S VP
Sbjct: 761 LSPQAEEPHLSPQPEEPCLCAVP-EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819

Query: 166 SHSMSSRRDTDSDTQDANDSSCKSS---------ERSLPDCTPHPNSISIDAGPRQAPKI 216
                S +  +S     ++  C S          E   P  +P P     +  P Q P  
Sbjct: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE--PGQCPAP 877

Query: 217 AQIKRNLSYGDNS------DPALEASSLPPPDPWLETSSSSPA-EPA 256
            ++      G+ S      +PAL     PP  P  E    SP+ EP+
Sbjct: 878 EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 56/246 (22%), Positives = 80/246 (32%), Gaps = 49/246 (19%)

Query: 24  PVPPRTTSKPF-------ISVTVQSSTESAQDTYLDSQDHKSEVT---SQSGLSNSSDSL 73
           P+ P   S PF       +S   +S    A +T L      S ++    +S LS   + L
Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561

Query: 74  DSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVD 133
            +S  PP  +R    P      PPP+              ES     P+        +  
Sbjct: 562 PTSP-PPEASRLSPPPEESPMSPPPE--------------ESPMSPPPEASRLFPPFEES 606

Query: 134 CIQPVPKEEP-SPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSER 192
            + P P+E P SP  +   +    ED   S  P  S  S            + S  S   
Sbjct: 607 PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS---------PPPEVSRLSPLP 657

Query: 193 SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSP 252
            +   +P P    +   P ++P              + P  EAS L PP     TS    
Sbjct: 658 VVSRLSPPPEESPLSPPPEESP--------------TSPPPEASRLSPPPEDSPTSPPPE 703

Query: 253 AEPAQP 258
             PA P
Sbjct: 704 DSPASP 709



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 38/134 (28%), Positives = 51/134 (38%), Gaps = 22/134 (16%)

Query: 86   GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK-----RKLSSIGIQVDCIQPVPK 140
            GV P P  PE  P  AA  SE      +   PE  PK     R  S     +      PK
Sbjct: 3088 GVEPGPLGPEERPPPAADASEP---RLASVLPEVKPKVEEGGRHPSPCQFTI----ATPK 3140

Query: 141  EEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPH 200
             EP+PA     +G++         P  SM   RDT   T   + SS  ++E++    T  
Sbjct: 3141 VEPAPAANSLGLGLK---------PGQSMMGSRDTRMGTGPFS-SSGHTAEKASFGATGG 3190

Query: 201  PNSISIDAGPRQAP 214
            P +  +   P   P
Sbjct: 3191 PPAHLLTPSPLSGP 3204


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 54/252 (21%), Positives = 89/252 (35%), Gaps = 18/252 (7%)

Query: 22   PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81
            PPPVP   T+ P + +  ++  E  +         ++   ++   S+S    D    P +
Sbjct: 853  PPPVP---TAVPTLCLPPEADAEPGRPK------KRAHSLNRYAASDSEPERDELLVPAA 903

Query: 82   V-------TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDC 134
                     R G + +  AP    K+             +  P   PKR  S++      
Sbjct: 904  AGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLA 963

Query: 135  IQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSL 194
             +PVP  EP           +   D   SV + S  S +   +  + ++      + R  
Sbjct: 964  DEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRP 1023

Query: 195  PDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLP-PPDPWLETSSSSPA 253
            P+  P P   S + G R A  +A +K   + G   +      +L  P    L T+   P 
Sbjct: 1024 PEGHPTPRPASPEPG-RVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPG 1082

Query: 254  EPAQPGACRRDG 265
            E A PG    DG
Sbjct: 1083 ESADPGPFVEDG 1094


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%)

Query: 19  KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76
           K+T   V   TT  +K   +   Q+ST+  + T    +    E TS   L+ +S  L   
Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197

Query: 77  T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129
           T +  + T+G     P+ P P  P + A+   ++ T T+ +S P    E AP    S+  
Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 255

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189
                  P   +EP+P T  +      ++   ++    + ++ +   +  ++   ++ K 
Sbjct: 256 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308

Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249
              + P   P P +   +  P    + A   +  +     +PA  A   P P    E + 
Sbjct: 309 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 366

Query: 250 SSPAEPA 256
           ++P EPA
Sbjct: 367 TTPKEPA 373



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%)

Query: 21  TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79
           TP    P TT KP  +   + +  + ++T   +   K   T+   L+ ++    + T P 
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512

Query: 80  ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129
              P+         PE P P  PK AA  +  E    T  E  P    E AP     +  
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187
                  P   +EP+P T  +    ++         S +      T              
Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632

Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247
            ++ +     TP   + +    P          + L+      P    S  P P    ET
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692

Query: 248 SSSSPAEPA 256
           + ++P EPA
Sbjct: 693 APTTPKEPA 701


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%)

Query: 19  KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76
           K+T   V   TT  +K   +   Q+ST+  + T    +    E TS   L+ +S  L   
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238

Query: 77  T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129
           T +  + T+G     P+ P P  P + A+   ++ T T+ +S P    E AP    S+  
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 296

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189
                  P   +EP+P T  +      ++   ++    + ++ +   +  ++   ++ K 
Sbjct: 297 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349

Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249
              + P   P P +   +  P    + A   +  +     +PA  A   P P    E + 
Sbjct: 350 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 407

Query: 250 SSPAEPA 256
           ++P EPA
Sbjct: 408 TTPKEPA 414



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%)

Query: 21  TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79
           TP    P TT KP  +   + +  + ++T   +   K   T+   L+ ++    + T P 
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553

Query: 80  ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129
              P+         PE P P  PK AA  +  E    T  E  P    E AP     +  
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187
                  P   +EP+P T  +    ++         S +      T              
Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673

Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247
            ++ +     TP   + +    P          + L+      P    S  P P    ET
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733

Query: 248 SSSSPAEPA 256
           + ++P EPA
Sbjct: 734 APTTPKEPA 742


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%)

Query: 19  KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76
           K+T   V   TT  +K   +   Q+ST+  + T    +    E TS   L+ +S  L   
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290

Query: 77  T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129
           T +  + T+G     P+ P P  P + A+   ++ T T+ +S P    E AP    S+  
Sbjct: 291 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 348

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189
                  P   +EP+P T  +      ++   ++    + ++ +   +  ++   ++ K 
Sbjct: 349 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401

Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249
              + P   P P +   +  P    + A   +  +     +PA  A   P P    E + 
Sbjct: 402 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459

Query: 250 SSPAEPA 256
           ++P EPA
Sbjct: 460 TTPKEPA 466



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%)

Query: 21  TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79
           TP    P TT KP  +   + +  + ++T   +   K   T+   L+ ++    + T P 
Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605

Query: 80  ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129
              P+         PE P P  PK AA  +  E    T  E  P    E AP     +  
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187
                  P   +EP+P T  +    ++         S +      T              
Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725

Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247
            ++ +     TP   + +    P          + L+      P    S  P P    ET
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785

Query: 248 SSSSPAEPA 256
           + ++P EPA
Sbjct: 786 APTTPKEPA 794



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 48/270 (17%), Positives = 94/270 (34%), Gaps = 35/270 (12%)

Query: 19  KKTPPPVPP----RTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD 74
           KK PPP       ++T+K       +  T+   ++   +++H      +S  S+SS S  
Sbjct: 76  KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS 135

Query: 75  SSTRPPSVTRGGVA---------------------PAPEAPEPPPKHAALKSEQGTLTSS 113
           S+ R    ++   A                     P P+ P      + L +    +T+ 
Sbjct: 136 STIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP 195

Query: 114 ESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRR 173
           ++      K   S        I P P   P+  T  ++     ++    +  + + + + 
Sbjct: 196 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 255

Query: 174 DTDSDTQDANDSSCKSSER-SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPA 232
            TD   +  +    +S E+ S  D  P    ++     +  PK     +  +     +P 
Sbjct: 256 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-----KPTPKAETTTKGPALTTPKEPT 310

Query: 233 ----LEASSLPPPDPWLETSSSSPAEPAQP 258
                E +S  P +P   T  S+P  P +P
Sbjct: 311 PTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%)

Query: 19  KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76
           K+T   V   TT  +K   +   Q+ST+  + T    +    E TS   L+ +S  L   
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331

Query: 77  T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129
           T +  + T+G     P+ P P  P + A+   ++ T T+ +S P    E AP    S+  
Sbjct: 332 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 389

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189
                  P   +EP+P T  +      ++   ++    + ++ +   +  ++   ++ K 
Sbjct: 390 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442

Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249
              + P   P P +   +  P    + A   +  +     +PA  A   P P    E + 
Sbjct: 443 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500

Query: 250 SSPAEPA 256
           ++P EPA
Sbjct: 501 TTPKEPA 507



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%)

Query: 21  TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79
           TP    P TT KP  +   + +  + ++T   +   K   T+   L+ ++    + T P 
Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646

Query: 80  ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129
              P+         PE P P  PK AA  +  E    T  E  P    E AP     +  
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706

Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187
                  P   +EP+P T  +    ++         S +      T              
Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766

Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247
            ++ +     TP   + +    P          + L+      P    S  P P    ET
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826

Query: 248 SSSSPAEPA 256
           + ++P EPA
Sbjct: 827 APTTPKEPA 835



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 48/270 (17%), Positives = 94/270 (34%), Gaps = 35/270 (12%)

Query: 19  KKTPPPVPP----RTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD 74
           KK PPP       ++T+K       +  T+   ++   +++H      +S  S+SS S  
Sbjct: 117 KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS 176

Query: 75  SSTRPPSVTRGGVA---------------------PAPEAPEPPPKHAALKSEQGTLTSS 113
           S+ R    ++   A                     P P+ P      + L +    +T+ 
Sbjct: 177 STIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP 236

Query: 114 ESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRR 173
           ++      K   S        I P P   P+  T  ++     ++    +  + + + + 
Sbjct: 237 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 296

Query: 174 DTDSDTQDANDSSCKSSER-SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPA 232
            TD   +  +    +S E+ S  D  P    ++     +  PK     +  +     +P 
Sbjct: 297 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-----KPTPKAETTTKGPALTTPKEPT 351

Query: 233 ----LEASSLPPPDPWLETSSSSPAEPAQP 258
                E +S  P +P   T  S+P  P +P
Sbjct: 352 PTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 40/215 (18%)

Query: 27  PRTTSKPFISVTV-QSSTESAQDTYLDSQDHKSEVTS---QSGLSNSSDSLDSSTRPPSV 82
           P   S+   SVT  Q   +++  T+ +SQ   S +     Q   S  SDS  +  +PPS 
Sbjct: 388 PTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSS 447

Query: 83  TRGGVAPAPEAPE--PPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPK 140
           +    AP P AP+  P P  +A  S   + ++S+S   +  + + SS   + +     P 
Sbjct: 448 S----AP-PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPA 502

Query: 141 EEPSPAT--KFQSIGVQVEDDWRSSV-------------------PSHSMSSRRDTDSDT 179
            EP P T  K+Q       D+W + V                   P    SS   T  + 
Sbjct: 503 PEPEPPTTNKWQL------DNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEH 556

Query: 180 QDANDSSCKSSERS--LPDCTPHPNSISIDAGPRQ 212
            ++ D   KSS ++   P   PHP   S    P Q
Sbjct: 557 SESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQ 591


>gi|82830424 gon-4-like isoform a [Homo sapiens]
          Length = 2240

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 47/192 (24%), Positives = 73/192 (38%), Gaps = 26/192 (13%)

Query: 48   DTYLDSQDHKS--EVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKS 105
            DT   S++  S  EVT Q+ L    +    +  P S           + EPP        
Sbjct: 1357 DTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSS-----------SQEPP-------- 1397

Query: 106  EQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVP 165
            ++GT  S     + + K  LSS+  +V    P  K E S +   QS+G  V  +      
Sbjct: 1398 DEGT--SGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKN 1455

Query: 166  SHSMSSRRDTDSDTQDANDSSCKSSER---SLPDCTPHPNSISIDAGPRQAPKIAQIKRN 222
                    D D  TQD  D    +SE    S+P+       ++  A  R+  +  + +  
Sbjct: 1456 GPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEE 1515

Query: 223  LSYGDNSDPALE 234
             S  +NS+P  E
Sbjct: 1516 NSQEENSEPEEE 1527


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 51/240 (21%), Positives = 88/240 (36%), Gaps = 20/240 (8%)

Query: 22  PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81
           P P+PP+   KP +++   +ST++            + V +Q+     +  +  + + P+
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTV-----------APVVTQAAPPTPTPPVPPAKKQPA 818

Query: 82  VTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE 141
                + P+P  P  P     L  +Q    S  + P  +P   + S+  Q+    P P  
Sbjct: 819 FPASYIPPSPPTPPVPVPPPTLPKQQ----SFCAKPPPSPLSPVPSVVKQIASQFPPP-- 872

Query: 142 EPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHP 201
              PA + Q +     +    S P+     +    S    + D      E SL    P P
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932

Query: 202 NSISIDAGPRQAPKIAQIKRNLSYG-DNSDPALEASSLPPPDPWLETS--SSSPAEPAQP 258
           + +     P          ++ S G   S  +      PPP P   +S  SSS AE  +P
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 35/136 (25%), Positives = 47/136 (34%), Gaps = 17/136 (12%)

Query: 22  PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81
           PPP PP     P +      S  SA   ++      S +T     S  S +L     PP 
Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY----STITRLQNASQHSGALFKPPTPPV 691

Query: 82  -----------VTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPE-AAPKRKLSSIG 129
                      V   GV P P  P PPP   +  ++      + S P+ +AP   L    
Sbjct: 692 MQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQ 751

Query: 130 IQVDCIQPVPKEEPSP 145
           +Q    Q  P   P P
Sbjct: 752 VQ-HITQVAPPTPPPP 766



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 33/130 (25%), Positives = 45/130 (34%), Gaps = 6/130 (4%)

Query: 16  VAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS---GLSNSSDS 72
           +A +  PPP PP   S+P   V    + +S        +   S +   S          S
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924

Query: 73  LDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSE--SHPEAAPKRKLSSIGI 130
           L     PPS       P P    P P  +    ++ + TSS     P   P+R  SSI  
Sbjct: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN-SSIKS 983

Query: 131 QVDCIQPVPK 140
                 P PK
Sbjct: 984 SSGAEHPEPK 993


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 52/239 (21%), Positives = 83/239 (34%), Gaps = 21/239 (8%)

Query: 23   PPVPPRTTSKPFISVTVQSSTESAQ-DTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81
            P  P  +   P  S+  ++S +SA     L S++  S + SQ  LS +  S      PP 
Sbjct: 1324 PEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPS-----NPP- 1377

Query: 82   VTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE 141
                G  PAP AP  PP  A  +      TS+   P +    +    G        +   
Sbjct: 1378 ----GAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETS 1433

Query: 142  EPSPATKFQSIGVQ-VEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPH 200
            +P   T    + VQ +        P+   +S RD  +  +     +        P+ +PH
Sbjct: 1434 QPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA--------PEPSPH 1485

Query: 201  PNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPG 259
              +     G + AP +      +S   +  P+       PP P     S     P + G
Sbjct: 1486 SGTPQPALG-QPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVG 1543



 Score = 32.7 bits (73), Expect = 0.69
 Identities = 48/190 (25%), Positives = 71/190 (37%), Gaps = 21/190 (11%)

Query: 36   SVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPE 95
            S+T +SS  S      D +   S+      +     +     R     R G      + E
Sbjct: 1643 SMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAE 1702

Query: 96   PPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPA-TKFQSIGV 154
            PPP      S+ GT+    SHP+    R L S        +P  ++  SPA T  +   V
Sbjct: 1703 PPP------SDMGTVGGQASHPQTLGARALGS-----PRKRPEQQDVSSPAKTVGRFSVV 1751

Query: 155  QVEDDWRSSVPSHSMSSRRDTDSDTQDANDS-SCKSSER------SLPDCTPHP-NSISI 206
              +D+W  + P HS+      D    +A  S   K + R      S+      P +S S 
Sbjct: 1752 STQDEWTLASP-HSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSG 1810

Query: 207  DAGPRQAPKI 216
            D GPR  P +
Sbjct: 1811 DEGPRARPPV 1820


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 105/470 (22%), Positives = 181/470 (38%), Gaps = 75/470 (15%)

Query: 37  VTVQSSTESAQ-DTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAP---APE 92
           ++VQ  TE      +L+  + +S   + S L+ +  S    ++ P V  G V+    +P 
Sbjct: 257 LSVQQETEDQNYGIFLEMMEARSRGHA-SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG 315

Query: 93  APEPPPK---HAALKSEQGTLTSSESHPEAA------PKRKLSS--IGIQVDCIQPVPKE 141
            P+P P+   +AA  S    +  SE+ P  A      P+R + S   G         P  
Sbjct: 316 TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPP 375

Query: 142 EPSPATK----FQSIGVQVEDD------WRSSVPSH------SMSSRRDTDSDTQDANDS 185
           EP PA +     QS+   V DD         + P+       + ++++D+DSD +    +
Sbjct: 376 EPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGN 435

Query: 186 SCKSSERSLPDCTPHPN-SISIDAGP-----------RQAPKIAQIKRNLSYGDN-SDPA 232
              +  +   D    P  S  + AGP            +A   A  K         S+P 
Sbjct: 436 PMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPE 495

Query: 233 LEASSLPPPDPWLETSSSSPAEPAQPGACR-RDGYWFLKLLQ--AETERLEGWCCQMDKE 289
            + SS+P   P   T+ +  A P  PG    R G       +  AE E  +G      + 
Sbjct: 496 TKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSES 555

Query: 290 TKENNLSEEVLGKVLS-----AVGSAQLLMSQKF---QQFRGLCEQNLNPDANPRPTAQD 341
             E  ++ ++L  V+      + GS     +  F        + +++  P   P P    
Sbjct: 556 DPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLP 615

Query: 342 LAGFW-----DLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAK 396
           L  F      DL  L +E+   K        +   +  +TP K K++KK      ++ A 
Sbjct: 616 LPAFRLKNDSDLFGLGLEEAGPKES------SEEGKEGKTPSKEKKKKKKKGKEEEEKAA 669

Query: 397 SKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYV 446
            K   S+ K S   ++ ++E R+R    +R    R+ +A   AD +E ++
Sbjct: 670 KKK--SKHKKSKDKEEGKEERRRR---QQRPPRSRERTA---ADELEAFL 711


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 82/355 (23%), Positives = 129/355 (36%), Gaps = 68/355 (19%)

Query: 88   APAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE----EP 143
            AP+PE   PP K  A +S +  + SS    E+  +R L  +  Q   IQ   +E    EP
Sbjct: 1120 APSPEKTLPPQKTVAAESHE-KVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREP 1178

Query: 144  SPATKFQSIGVQVEDDWRSS----------VPSHSMSSRRDTDSDTQDANDSSCKSSERS 193
            S     Q  GV + +D + S            + + S ++ T+     A     + +E++
Sbjct: 1179 SRRVT-QEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKT 1237

Query: 194  LPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPA 253
            LP  +P P                Q++R  S       AL+ S + PP P   ++  +P 
Sbjct: 1238 LPSGSPRP---------------GQLERPTSL------ALD-SRVSPPAP--GSAPETPE 1273

Query: 254  EPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEV---LGKVLSAVGSA 310
            + ++P    R           E     G   Q+ +      L+  V    GK L A  S 
Sbjct: 1274 DKSKPCGSPR---------VQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVAAASP 1324

Query: 311  QLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANS 370
              ++SQ       L +++    A   PT +    F      S  D+S     L    A +
Sbjct: 1325 SAMLSQSLD----LSDRHRATGAALTPTEERRTSF------STSDVSKLLPSL----AKA 1370

Query: 371  WQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAK 425
                ET +  +  KK  P V KK      ++     S  S    +   KRL   K
Sbjct: 1371 QPAAETTDGERSAKK--PAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHK 1423


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 82/355 (23%), Positives = 129/355 (36%), Gaps = 68/355 (19%)

Query: 88   APAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE----EP 143
            AP+PE   PP K  A +S +  + SS    E+  +R L  +  Q   IQ   +E    EP
Sbjct: 1120 APSPEKTLPPQKTVAAESHE-KVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREP 1178

Query: 144  SPATKFQSIGVQVEDDWRSS----------VPSHSMSSRRDTDSDTQDANDSSCKSSERS 193
            S     Q  GV + +D + S            + + S ++ T+     A     + +E++
Sbjct: 1179 SRRVT-QEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKT 1237

Query: 194  LPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPA 253
            LP  +P P                Q++R  S       AL+ S + PP P   ++  +P 
Sbjct: 1238 LPSGSPRP---------------GQLERPTSL------ALD-SRVSPPAP--GSAPETPE 1273

Query: 254  EPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEV---LGKVLSAVGSA 310
            + ++P    R           E     G   Q+ +      L+  V    GK L A  S 
Sbjct: 1274 DKSKPCGSPR---------VQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVAAASP 1324

Query: 311  QLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANS 370
              ++SQ       L +++    A   PT +    F      S  D+S     L    A +
Sbjct: 1325 SAMLSQSLD----LSDRHRATGAALTPTEERRTSF------STSDVSKLLPSL----AKA 1370

Query: 371  WQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAK 425
                ET +  +  KK  P V KK      ++     S  S    +   KRL   K
Sbjct: 1371 QPAAETTDGERSAKK--PAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHK 1423


>gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo
           sapiens]
          Length = 389

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 86  GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPV------- 138
           GV   P AP P    A +   Q  L S E  P+A    ++   G Q   +QPV       
Sbjct: 22  GVGEGPAAPSPGS--APVPGTQPPLQSFEGSPDAGQTVEVKPAGEQP--LQPVLNAVAAG 77

Query: 139 -PKEEPSPATKFQSIGVQVEDDWRSS---VPSHSMSSRRDTDSDTQDANDSSCKSSERSL 194
            P  +P P  +  + G  V     +     P    +S  D+DSD++  +DSS  SS  S 
Sbjct: 78  TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137

Query: 195 PDCTPHPNSISI 206
              +   + IS+
Sbjct: 138 SSSSSSSSCISL 149


>gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo
           sapiens]
          Length = 494

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 86  GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPV------- 138
           GV   P AP P    A +   Q  L S E  P+A    ++   G Q   +QPV       
Sbjct: 22  GVGEGPAAPSPGS--APVPGTQPPLQSFEGSPDAGQTVEVKPAGEQP--LQPVLNAVAAG 77

Query: 139 -PKEEPSPATKFQSIGVQVEDDWRSS---VPSHSMSSRRDTDSDTQDANDSSCKSSERSL 194
            P  +P P  +  + G  V     +     P    +S  D+DSD++  +DSS  SS  S 
Sbjct: 78  TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137

Query: 195 PDCTPHPNSISI 206
              +   + IS+
Sbjct: 138 SSSSSSSSCISL 149


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 59/254 (23%), Positives = 93/254 (36%), Gaps = 58/254 (22%)

Query: 22  PPPVPPR-----TTSKPFISVTVQSSTESA-QDTYLDSQDH--KSEVTSQSGLSNSSDSL 73
           PPP PP      T+S+P++     S ++S    +YL        S  +SQS LS+S   L
Sbjct: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYL 225

Query: 74  DSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHP-EAAPKRKLSSIGIQV 132
            SS   PS    G + +     PPP      +  G  T+ +  P E+  K K        
Sbjct: 226 PSSQASPSRPSQGHSKSQLLAPPPP-----SAPPGNKTTVQQEPLESGAKNK------ST 274

Query: 133 DCIQPVPKEEPSPATK-------FQSIGVQVEDDWRSSVPSHSMSS--RRDTDSDTQDAN 183
           +  Q  P+ +PS  T        ++   + ++   +  +P H       +DT    ++  
Sbjct: 275 EQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKE-- 332

Query: 184 DSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDP 243
                  E ++P  +  P S S +  P   P                       +PPP P
Sbjct: 333 -------EVTVPATSQVPESPSSEEPPLPPPN--------------------EEVPPPLP 365

Query: 244 WLETSSSSPAEPAQ 257
             E  S  P E A+
Sbjct: 366 PEEPQSEDPEEDAR 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,323,524
Number of Sequences: 37866
Number of extensions: 1141561
Number of successful extensions: 11845
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 497
Number of HSP's that attempted gapping in prelim test: 9633
Number of HSP's gapped (non-prelim): 2639
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press