BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|34335251 disks large-associated protein 4 isoform b [Homo sapiens] (453 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|34335251 disks large-associated protein 4 isoform b [Homo sap... 911 0.0 gi|34335253 disks large-associated protein 4 isoform a [Homo sap... 813 0.0 gi|109891938 disks large-associated protein 4 isoform c [Homo sa... 577 e-164 gi|19923274 discs large homolog-associated protein 1 isoform alp... 425 e-119 gi|51339031 discs large homolog-associated protein 1 isoform bet... 425 e-119 gi|38202224 discs large-associated protein 2 [Homo sapiens] 393 e-109 gi|122937233 discs, large (Drosophila) homolog-associated protei... 311 1e-84 gi|226371669 discs large homolog 7 isoform b [Homo sapiens] 83 4e-16 gi|226371667 discs large homolog 7 isoform a [Homo sapiens] 83 4e-16 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 48 2e-05 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 45 1e-04 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 43 5e-04 gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 43 7e-04 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 9e-04 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 42 0.001 gi|18079216 CASK interacting protein 1 [Homo sapiens] 41 0.002 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 41 0.003 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 41 0.003 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 41 0.003 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 41 0.003 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 41 0.003 gi|82830424 gon-4-like isoform a [Homo sapiens] 40 0.004 gi|47132519 Ras association and pleckstrin homology domains 1 is... 40 0.006 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 40 0.006 gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 39 0.007 gi|194272142 myosin IXB isoform 2 [Homo sapiens] 39 0.007 gi|33356170 myosin IXB isoform 1 [Homo sapiens] 39 0.007 gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo s... 39 0.007 gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo s... 39 0.007 gi|146134388 YLP motif containing 1 [Homo sapiens] 39 0.007 >gi|34335251 disks large-associated protein 4 isoform b [Homo sapiens] Length = 453 Score = 911 bits (2354), Expect = 0.0 Identities = 453/453 (100%), Positives = 453/453 (100%) Query: 1 MALCLELLKQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEV 60 MALCLELLKQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEV Sbjct: 1 MALCLELLKQCSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEV 60 Query: 61 TSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA 120 TSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA Sbjct: 61 TSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA 120 Query: 121 PKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQ 180 PKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQ Sbjct: 121 PKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQ 180 Query: 181 DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 240 DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP Sbjct: 181 DANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP 240 Query: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL Sbjct: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300 Query: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF Sbjct: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360 Query: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR Sbjct: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420 Query: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL Sbjct: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453 >gi|34335253 disks large-associated protein 4 isoform a [Homo sapiens] Length = 989 Score = 813 bits (2099), Expect = 0.0 Identities = 416/444 (93%), Positives = 420/444 (94%), Gaps = 7/444 (1%) Query: 12 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD Sbjct: 551 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 610 Query: 72 SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ 131 SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ Sbjct: 611 SLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQ 670 Query: 132 VDCIQPVP--KEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189 + E+ P ++I V SSVPSHSMSSRRDTDSDTQDANDSSCKS Sbjct: 671 ERTRRNGSHLSEDNGP----KAIDVMAPSS-ESSVPSHSMSSRRDTDSDTQDANDSSCKS 725 Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS Sbjct: 726 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 785 Query: 250 SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS 309 SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS Sbjct: 786 SSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGS 845 Query: 310 AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN 369 AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN Sbjct: 846 AQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKAN 905 Query: 370 SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS 429 SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS Sbjct: 906 SWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAAS 965 Query: 430 VRQNSATESADSIEIYVPEAQTRL 453 VRQNSATESADSIEIYVPEAQTRL Sbjct: 966 VRQNSATESADSIEIYVPEAQTRL 989 >gi|109891938 disks large-associated protein 4 isoform c [Homo sapiens] Length = 285 Score = 577 bits (1486), Expect = e-164 Identities = 285/285 (100%), Positives = 285/285 (100%) Query: 169 MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN 228 MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN Sbjct: 1 MSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN 60 Query: 229 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK 288 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK Sbjct: 61 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDK 120 Query: 289 ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL 348 ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL Sbjct: 121 ETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDL 180 Query: 349 LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD 408 LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD Sbjct: 181 LQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASD 240 Query: 409 ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453 ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL Sbjct: 241 ASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 285 >gi|19923274 discs large homolog-associated protein 1 isoform alpha [Homo sapiens] Length = 977 Score = 425 bits (1092), Expect = e-119 Identities = 231/453 (50%), Positives = 306/453 (67%), Gaps = 18/453 (3%) Query: 12 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71 SSC+ YKKTPPPVPPRTT+KPFIS+T QSSTESAQD Y+D Q + ++ SQSGLSNS++ Sbjct: 532 SSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTE 591 Query: 72 SLDSSTRPPSVTRGGVA----PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSS 127 SLDS + A PA + + T+T+ + + K + S Sbjct: 592 SLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLS 651 Query: 128 IGIQVD-CIQPVPKEEPSPATKFQSIGVQVEDD--WRSSVPSHSMSSRRDTDSDTQDAND 184 IGIQVD +P E +KFQS+GVQVE++ +R S+S+++ D D D + Sbjct: 652 IGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLE 711 Query: 185 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYG----DNSDPALEASSLPP 240 +S +S E + P P + + Q N + D+ D + S LPP Sbjct: 712 NSLESIE---DNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPP 768 Query: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300 PDPW+++ + P E Q C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++L Sbjct: 769 PDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDIL 828 Query: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360 GK+ +AVGSAQLLM+QKF QFR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKF Sbjct: 829 GKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKF 888 Query: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420 DEL+ LKAN+W+ ++ +K+ E++ PPPVPKKPAK + R+++ ++S QRQEARKR Sbjct: 889 DELHQLKANNWKQMDPLDKK--ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKR 944 Query: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453 L+AAKRAASVRQNSATESA+SIEIY+PEAQTRL Sbjct: 945 LMAAKRAASVRQNSATESAESIEIYIPEAQTRL 977 >gi|51339031 discs large homolog-associated protein 1 isoform beta [Homo sapiens] Length = 675 Score = 425 bits (1092), Expect = e-119 Identities = 231/453 (50%), Positives = 306/453 (67%), Gaps = 18/453 (3%) Query: 12 SSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSD 71 SSC+ YKKTPPPVPPRTT+KPFIS+T QSSTESAQD Y+D Q + ++ SQSGLSNS++ Sbjct: 230 SSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTE 289 Query: 72 SLDSSTRPPSVTRGGVA----PAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSS 127 SLDS + A PA + + T+T+ + + K + S Sbjct: 290 SLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLS 349 Query: 128 IGIQVD-CIQPVPKEEPSPATKFQSIGVQVEDD--WRSSVPSHSMSSRRDTDSDTQDAND 184 IGIQVD +P E +KFQS+GVQVE++ +R S+S+++ D D D + Sbjct: 350 IGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLE 409 Query: 185 SSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYG----DNSDPALEASSLPP 240 +S +S E + P P + + Q N + D+ D + S LPP Sbjct: 410 NSLESIE---DNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPP 466 Query: 241 PDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVL 300 PDPW+++ + P E Q C RDG+WFLKLLQAE +R+EGWC QM++E +ENNL E++L Sbjct: 467 PDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDIL 526 Query: 301 GKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKF 360 GK+ +AVGSAQLLM+QKF QFR LCE+NLNP+A+PRPT+QDLAGFWD+LQLSIE+ISMKF Sbjct: 527 GKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKF 586 Query: 361 DELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKR 420 DEL+ LKAN+W+ ++ +K+ E++ PPPVPKKPAK + R+++ ++S QRQEARKR Sbjct: 587 DELHQLKANNWKQMDPLDKK--ERRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKR 642 Query: 421 LLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453 L+AAKRAASVRQNSATESA+SIEIY+PEAQTRL Sbjct: 643 LMAAKRAASVRQNSATESAESIEIYIPEAQTRL 675 >gi|38202224 discs large-associated protein 2 [Homo sapiens] Length = 975 Score = 393 bits (1010), Expect = e-109 Identities = 226/462 (48%), Positives = 295/462 (63%), Gaps = 42/462 (9%) Query: 18 YKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS--GLSNSSDSLDS 75 YKKTPPPVPPRTTSKP ISVT QSSTES QD Y DS+ + Q GL NS+DSLDS Sbjct: 530 YKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDS 589 Query: 76 STRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCI 135 + ++ A + P + +++++ + S++ E K + SSIGIQ Sbjct: 590 NK---AMNLALETAAAQRHLPESQSSSVRTSDKAILVSKA--EELLKSRCSSIGIQDSEF 644 Query: 136 ---QPVPKEEPSPAT----------KFQSIGVQVEDDWRSSVPSHSMSSRRDTDSD---- 178 QP P+ + AT ++ S+GVQVED+ R S S +D Sbjct: 645 PEHQPYPRSDVETATDSDTESRGLREYHSVGVQVEDEKRHGRFKRSNSVTAAVQADLELE 704 Query: 179 -------TQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDP 231 T+D S +R TP S A + + + SY ++ Sbjct: 705 GFPGHITTEDKGLQFGSSFQRHSEPSTPTQYS---------AVRTVRTQGLFSYREDYRT 755 Query: 232 ALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETK 291 ++ S+LPPPDPWLE + + E + CRRDG WFLKLL AET+R+EGWC +M++E + Sbjct: 756 QVDTSTLPPPDPWLEPAIDT-VETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAE 814 Query: 292 ENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQL 351 EN+LSEE+LGK+ SAVGSAQLLMSQKFQQF LC+QN++P A PRPT+QDLAG+WD+LQL Sbjct: 815 ENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQL 874 Query: 352 SIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASD 411 SIED+SMKFDEL L+ N W+++E+PE RKEE+K PPP+PKKP K K ++R+K+ D D Sbjct: 875 SIEDVSMKFDELQRLRLNDWKMMESPE-RKEERKVPPPIPKKPPKGKFPITREKSLDLPD 933 Query: 412 KQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453 +QRQEAR+RL+AAKRAAS RQNSA+E ADSIEIY+PEAQTRL Sbjct: 934 RQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQTRL 975 >gi|122937233 discs, large (Drosophila) homolog-associated protein 3 [Homo sapiens] Length = 979 Score = 311 bits (796), Expect = 1e-84 Identities = 193/466 (41%), Positives = 261/466 (56%), Gaps = 53/466 (11%) Query: 18 YKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSST 77 ++K PPP+PP + + P IS+T QSST+SA +++ T+ G + S D Sbjct: 537 FRKAPPPIPPGSQAPPRISITAQSSTDSAHESF----------TAAEGPARRCSSADGLD 586 Query: 78 RPPSVTRG-GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQ 136 P R +AP P P P +K+ G E A ++ SIG+QV+ I Sbjct: 587 GPAMGARTLELAPVPPRASPKPPTLIIKTIPGR---EELRSLARQRKWRPSIGVQVETIS 643 Query: 137 PVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSD-------------TQDAN 183 E S +F SIGVQVE+D R + S S +D T+D Sbjct: 644 DSDTENRS-RREFHSIGVQVEEDKRRARFKRSNSVTAGVQADLELEGLAGLATVATEDKA 702 Query: 184 DSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDN-----SDPALEASSL 238 +S +R + P P + + + + +Y + PA + S Sbjct: 703 LQFGRSFQRHASEPQPGPRAPTYSVF-----RTVHTQGQWAYREGYPLPYEPPATDGSPG 757 Query: 239 PPPDP-----------WLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMD 287 P P P W+E S S + + C RDG WF+K+L+AE E+LE WC QM+ Sbjct: 758 PAPAPTPGPGAGRRDSWIERGSRSLPDSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQME 817 Query: 288 KETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWD 347 +E ++ L EE+L K+ SAVGS QLL+SQK QQF LC+Q+++P A P PT QDLAGFWD Sbjct: 818 REAEDYELPEEILEKIRSAVGSTQLLLSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWD 877 Query: 348 LLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKAS 407 LLQLSIED+++KF EL LKANSW+L+E KEEKK PPP+PKKP + + ++++ Sbjct: 878 LLQLSIEDVTLKFLELQQLKANSWKLLEP----KEEKKVPPPIPKKPLRGRGVPVKERSL 933 Query: 408 DASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL 453 D+ D+QRQEARKRLLAAKRAAS R +SATESADSIEIY+PEAQTRL Sbjct: 934 DSVDRQRQEARKRLLAAKRAASFRHSSATESADSIEIYIPEAQTRL 979 >gi|226371669 discs large homolog 7 isoform b [Homo sapiens] Length = 842 Score = 83.2 bits (204), Expect = 4e-16 Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%) Query: 267 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 326 +F +LQ+ETE+L C + D++ E ++ ++ + +AVG +LLM ++F+QF GL + Sbjct: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490 Query: 327 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 386 T DL GFWD++ IED+ KF+ L L+ + WQ+ + Sbjct: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548 Query: 387 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 442 V +K S A S+ K DA R AR RL A K A +RQ E+A S+ Sbjct: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599 >gi|226371667 discs large homolog 7 isoform a [Homo sapiens] Length = 846 Score = 83.2 bits (204), Expect = 4e-16 Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%) Query: 267 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 326 +F +LQ+ETE+L C + D++ E ++ ++ + +AVG +LLM ++F+QF GL + Sbjct: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490 Query: 327 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 386 T DL GFWD++ IED+ KF+ L L+ + WQ+ + Sbjct: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548 Query: 387 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 442 V +K S A S+ K DA R AR RL A K A +RQ E+A S+ Sbjct: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 47.8 bits (112), Expect = 2e-05 Identities = 59/242 (24%), Positives = 86/242 (35%), Gaps = 38/242 (15%) Query: 23 PPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSV 82 P VP +P S Q SA +++ +S +S S S+SS S SS+ S Sbjct: 2499 PGVPHSDVGEPPASTGAQQP--SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS- 2555 Query: 83 TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEE 142 + S +S PE A KR S + ++ E Sbjct: 2556 ------------------SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597 Query: 143 PSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPN 202 P+PA + + SS S S SS + S + ++ SS SS S P P Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657 Query: 203 SISIDAGPRQAP-------------KIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249 ++ A P++ P + R+LSY P P P P + SS Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY----SPVERRRPSPQPSPRDQQSS 2713 Query: 250 SS 251 SS Sbjct: 2714 SS 2715 Score = 37.7 bits (86), Expect = 0.022 Identities = 43/188 (22%), Positives = 69/188 (36%), Gaps = 19/188 (10%) Query: 55 DHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGT----- 109 D KS ++ + S SS + R + G +PE P P+ +S G+ Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645 Query: 110 ------LTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSS 163 +S+ES PE PK + + G + +P K P + ++ R S Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSR-SSPEPKTKSRTPPRRRSSRSSPELTRKARLS 1704 Query: 164 VPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNL 223 S S SS +T S T + RS +P P S + R++ + K Sbjct: 1705 RRSRSASSSPETRSRTPPRH-------RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757 Query: 224 SYGDNSDP 231 G + P Sbjct: 1758 RRGRSPSP 1765 Score = 35.0 bits (79), Expect = 0.14 Identities = 67/267 (25%), Positives = 97/267 (36%), Gaps = 40/267 (14%) Query: 17 AYKKTPPPVPP--RTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD 74 A +TPP P R TS+ S + + +Q +QD S S+ S L Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVP-SAFSDQSRCLI 2463 Query: 75 SSTRP----PSVTRGGVAPAPEAPEPPPKHAALKS--EQGTLTSSESHPEAAPKRKLSSI 128 + T P S++ G VA + H + S G S P A S Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGD---HNGMLSVPAPGVPHSDVGEPPA-------ST 2513 Query: 129 GIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSC- 187 G Q QP PA + +S SS S S SS + S + D+ SS Sbjct: 2514 GAQ----QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569 Query: 188 ---KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPW 244 + + + +P TP P + P + P A+ KR S +S + +SS Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPE-PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628 Query: 245 LETSSSSPAE------------PAQPG 259 +SSSS + PA+PG Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPG 2655 Score = 34.3 bits (77), Expect = 0.24 Identities = 43/176 (24%), Positives = 64/176 (36%), Gaps = 27/176 (15%) Query: 57 KSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESH 116 KS+ + S SS S PP +R + PPPK ++ S +SH Sbjct: 789 KSQTPPRRSRSGSSQPKAKSRTPPRRSRS-------SSSPPPK------QKSKTPSRQSH 835 Query: 117 PEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD 176 ++P K+ S P SP QS+ Q + SS P + SR + Sbjct: 836 SSSSPHPKVKS------GTPPRQGSITSPQANEQSVTPQRRSCFESS-PDPELKSRTPSR 888 Query: 177 SDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPA 232 ++ KSS TP S S + P+ K R S+ +S P+ Sbjct: 889 HSCSGSSPPRVKSS-------TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937 Score = 32.3 bits (72), Expect = 0.91 Identities = 22/77 (28%), Positives = 34/77 (44%) Query: 33 PFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPE 92 P + + QS+ S + S D + S S SS LD+ R PS R A +PE Sbjct: 1367 PSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426 Query: 93 APEPPPKHAALKSEQGT 109 + P+ + +S G+ Sbjct: 1427 MKDGLPRTPSRRSRSGS 1443 Score = 31.6 bits (70), Expect = 1.5 Identities = 50/216 (23%), Positives = 77/216 (35%), Gaps = 13/216 (6%) Query: 56 HKSEVTSQSGLSNSSDSLDSSTRPPSVTRG--GVAPAPEAPEPPPKHAALKSEQGTLTSS 113 H+S + S++S S S + T G +P+P + A T T Sbjct: 261 HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320 Query: 114 ESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSR- 172 S PE A K+ S + + PSP+ + S G + H S + Sbjct: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQP 380 Query: 173 -RDTDSDTQDANDSSCKSSERS-LPDCTPH--PNSISIDAGPRQAPKIAQIKRNLSYGDN 228 T + N S S R P +P P S S ++ P +P+ ++ R+ S Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSP-PSPQPTKVSRHASSSPE 439 Query: 229 SDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264 S P P E SSS ++ G +RD Sbjct: 440 S-----PKPAPAPGSHREISSSPTSKNRSHGRAKRD 470 Score = 30.4 bits (67), Expect = 3.4 Identities = 48/219 (21%), Positives = 82/219 (37%), Gaps = 39/219 (17%) Query: 75 SSTRPPSVTRGGVAPAPEAPE-------------PPPKHAALKSEQGTLTSSESHPEAAP 121 SS P R PAPE P+ P PK K ++ SES Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208 Query: 122 KRKLSSIGIQVDCIQPVPKE--EPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDT 179 ++K S + ++ P+P +K +S + + ++ S + R T +D+ Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268 Query: 180 QDANDSS--------CKSSERSLPDCTPHPNSISIDAGPR-------------QAPKIAQ 218 ++D+S K+ +L +P P S G +P+ A Sbjct: 269 ASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT 328 Query: 219 IKRNLSYGD-NSDPALEASSLPPPDPWLETSSSSPAEPA 256 + + Y D + D ++++ P P P E SS+ P PA Sbjct: 329 KQPSSPYEDKDKDKKEKSATRPSPSP--ERSSTGPEPPA 365 Score = 29.3 bits (64), Expect = 7.7 Identities = 14/65 (21%), Positives = 30/65 (46%) Query: 377 PEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSAT 436 P++ E +PP P P K + + S +S +S + ++ ++S +S++ Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645 Query: 437 ESADS 441 S+ S Sbjct: 2646 SSSPS 2650 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 45.4 bits (106), Expect = 1e-04 Identities = 85/448 (18%), Positives = 160/448 (35%), Gaps = 48/448 (10%) Query: 26 PPRTTSKPFISVTVQSSTESAQDTYLDSQD--HKSEVTSQSGLSNSSDSLDSSTRPPSVT 83 PP+ VTV++ T++ + + +S S S+SS S DS + T Sbjct: 179 PPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAAT 238 Query: 84 RGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEP 143 P + P AA + + +S +S + ++K P P Sbjct: 239 PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAP 298 Query: 144 SPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNS 203 P +S+G Q P ++ ++ +S +++S S E P P Sbjct: 299 PPK---KSLGTQP--------PKKAVEKQQPVESSEDSSDESDSSSEEEKKP-----PTK 342 Query: 204 ISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPA----EPA-QP 258 + + P + + S +SD + + + P + SS+ PA PA +P Sbjct: 343 AVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKP 402 Query: 259 GACRRD---GYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMS 315 A + G L +A++ E + ++E + V A A L + Sbjct: 403 AAAPKQPVGGGQKLLTRKADSSSSE----EESSSSEEEKTKKMVATTKPKATAKAALSLP 458 Query: 316 QKFQQFRGLCEQNLNPDANP-------------RPTAQDLAGFWDLLQLSIEDISMKFDE 362 K Q +G + + + D++ + Q +AG E Sbjct: 459 AK-QAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAG--GAAPSKPASAKKGKAE 515 Query: 363 LYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLL 422 + ++ E EK K + P P PK S KA+ S+++ +E +K + Sbjct: 516 SSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAV 575 Query: 423 AAKRAASVRQNSATESADSIEIYVPEAQ 450 ++ S+++ E+A E P+A+ Sbjct: 576 VVSKSGSLKKRKQNEAAKEAE--TPQAK 601 Score = 42.4 bits (98), Expect = 9e-04 Identities = 50/241 (20%), Positives = 87/241 (36%), Gaps = 40/241 (16%) Query: 58 SEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHP 117 ++ + S SSD D + + GV P +A + PPK A S+ + +SSE P Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK-SSDSDSDSSSEDEP 179 Query: 118 EAAPKRKLSSIGIQVDCIQP------VPK-----------------------EEPSPATK 148 K K++ + ++ P PK EE + AT Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239 Query: 149 FQSIG----VQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS-----SERSLPDCTP 199 +++ V ++ P+ SS D+ SD ++ K+ S P P Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP 299 Query: 200 HPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPG 259 S+ + K ++ + D SD + E PP + +++ P PA+ Sbjct: 300 PKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP-PPAKKA 358 Query: 260 A 260 A Sbjct: 359 A 359 Score = 39.3 bits (90), Expect = 0.007 Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 37/196 (18%) Query: 67 SNSSDSLDSSTRPPSV----TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK 122 ++SSDS DSS V + PA PP K AA SE + S + + Sbjct: 82 ASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQ 141 Query: 123 RKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDA 182 +K QPV K GV+ + + P + SS D+DS ++D Sbjct: 142 KK-----------QPVQK------------GVKPQAKAAKAPPKKAKSSDSDSDSSSEDE 178 Query: 183 NDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPD 242 + K P TP +++ A + PK A+ ++ G + + +SS D Sbjct: 179 PPKNQK------PKITP----VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSD 228 Query: 243 PWLETSSSSPAEPAQP 258 E +++ + P Sbjct: 229 DSEEEKAAATPKKTVP 244 Score = 37.0 bits (84), Expect = 0.037 Identities = 57/253 (22%), Positives = 89/253 (35%), Gaps = 48/253 (18%) Query: 18 YKKTPPPV--PPRT---TSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDS 72 Y PPP PP+ T P +V Q ES++D SSD Sbjct: 289 YSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSED--------------------SSDE 328 Query: 73 LDSST----RPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSI 128 DSS+ +PP T+ V+ A +PPP A +S + S S + AP + + Sbjct: 329 SDSSSEEEKKPP--TKAVVSKA--TTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGT- 383 Query: 129 GIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCK 188 PA +S V+ + V R DS + + SS + Sbjct: 384 ---------TKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSE 434 Query: 189 SSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALE-----ASSLPPPDP 243 + T P + + A A + Q R+ S +S + E + S P Sbjct: 435 EEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKP 494 Query: 244 WLETSSSSPAEPA 256 ++P++PA Sbjct: 495 QKVAGGAAPSKPA 507 Score = 35.4 bits (80), Expect = 0.11 Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 31/135 (22%) Query: 19 KKTPPPVPPRTTSKPFISVTV----QSSTESAQDTYLDSQDHKSEVTSQSGL-------- 66 KK P+ T+K +S+ Q S +S+ D+ S + + E TS+S + Sbjct: 439 KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVA 498 Query: 67 ------------------SNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQG 108 SNSS S DSS +G +P P+AP+ +AL ++ G Sbjct: 499 GGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT-SALTAQNG 557 Query: 109 TLTSSESHPEAAPKR 123 + E K+ Sbjct: 558 KAAKNSEEEEEEKKK 572 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 43.1 bits (100), Expect = 5e-04 Identities = 55/223 (24%), Positives = 82/223 (36%), Gaps = 18/223 (8%) Query: 42 STESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHA 101 S + AQ +++ +S +S SG S+SS S SS G ++ Sbjct: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNC 2602 Query: 102 ALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWR 161 + S + +S S ++ SS S ++ S Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSS--------SSSSSSSSSSSSSSSSSSSSSS 2654 Query: 162 SSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKR 221 SS S S SS + S T D DSSC S + + P T P++ + A P +A K A R Sbjct: 2655 SSSSSSSSSSSSSSSSSTTD-EDSSCSSDDEAAPAPTAGPSAQA--ALPTKATKQAGKAR 2711 Query: 222 NLSYGDNSDPALEASSLPPPDPWLETSSSSPAEP-AQPGACRR 263 ++ PPP P + P +P AQ GA R Sbjct: 2712 PSAHSPGKKTPAPQPQAPPPQP------TQPLQPKAQAGAKSR 2748 Score = 32.7 bits (73), Expect = 0.69 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Query: 29 TTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVA 88 ++S S + SS+ S+ + S S +S S S+SS S S+T S Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684 Query: 89 PAPEAPEPPPKHAALKSEQGTLTSSESHPEA-APKRKLSSIGIQVDCIQPVPKEEP 143 AP P AAL + + T + ++ P A +P +K + Q QP +P Sbjct: 2685 AAPAPTAGPSAQAALPT-KATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQP 2739 >gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 [Homo sapiens] Length = 559 Score = 42.7 bits (99), Expect = 7e-04 Identities = 53/217 (24%), Positives = 75/217 (34%), Gaps = 13/217 (5%) Query: 22 PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81 PPP PPR +SK + + Q + TS S+SS S + S Sbjct: 275 PPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKS 334 Query: 82 VTRGGVAPAPEAPEPPPKHAALK---SEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPV 138 TRG A P K ++ SE SES + SS +P Sbjct: 335 STRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPS 394 Query: 139 PKEEPSPATKF----QSIGVQVEDDWRSSVPSHSMSSRRDT-----DSDTQDANDSSCKS 189 P QS +D + + RD+ DS++ ++ DSS S Sbjct: 395 QNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPS 454 Query: 190 SERSLPDCTPHPNS-ISIDAGPRQAPKIAQIKRNLSY 225 E P P PNS +S P K +I + +Y Sbjct: 455 REPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTY 491 Score = 40.4 bits (93), Expect = 0.003 Identities = 53/242 (21%), Positives = 88/242 (36%), Gaps = 29/242 (11%) Query: 27 PRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD----SSTRPPSV 82 P+ T S + + +++H+ S +SS L+ S++ S Sbjct: 172 PKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSR 231 Query: 83 TRGGVAPAPEAPEPPPKHA------ALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQ 136 G E PPPK A ALK + TS + P P + + Sbjct: 232 KLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPP-----RASSKR 286 Query: 137 PVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPD 196 P + P P+ K Q + + S + S R + S D + KSS R Sbjct: 287 PATADSPKPSAKKQK-----KSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRG--- 338 Query: 197 CTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPP-PDPWLETSSSSPAEP 255 + ++ PR+A K +++ + S + S + A S P ++SS S EP Sbjct: 339 -----EKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEP 393 Query: 256 AQ 257 +Q Sbjct: 394 SQ 395 Score = 30.0 bits (66), Expect = 4.5 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%) Query: 386 PPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESAD 440 PPPP P A SK + D ++ KQ++ + K +A S R +S++ +D Sbjct: 273 PPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAP-GTSPRTSSSSSFSD 326 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 42.4 bits (98), Expect = 9e-04 Identities = 47/215 (21%), Positives = 80/215 (37%), Gaps = 3/215 (1%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS + + +S S+ S S SNSSDS D+S S + + ++ + Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 ++ S + +S S + + SS D + + S D Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738 Query: 161 RSSVPSHSMSSRRDTD-SDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQI 219 SS S S S +D SD+ D+++SS S D + N S D+ + Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN--SSDSNDSSNSSDSSD 796 Query: 220 KRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAE 254 N S NS + ++S D + SS+ ++ Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831 Score = 37.0 bits (84), Expect = 0.037 Identities = 45/213 (21%), Positives = 78/213 (36%) Query: 42 STESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHA 101 S++S+ DS D + +S S SNSSDS DSS S + + ++ + Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763 Query: 102 ALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWR 161 + S + +S S + SS S + S + Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 162 SSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKR 221 S + S SS SD+ D++DSS S S +S S D+ + Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883 Query: 222 NLSYGDNSDPALEASSLPPPDPWLETSSSSPAE 254 + + NS + ++S+ D ++SS ++ Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916 Score = 36.6 bits (83), Expect = 0.048 Identities = 46/211 (21%), Positives = 76/211 (36%), Gaps = 2/211 (0%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS S DS D S+ + S SNSSDS DSS S + + + + Sbjct: 755 SSDSSDSSNSSDSSD-SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 + S+ + S + +++ S D + + + S D Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873 Query: 161 RSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIK 220 +S S S SS + S++ D++DSS S S +S S ++ + Sbjct: 874 SNSSDS-SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932 Query: 221 RNLSYGDNSDPALEASSLPPPDPWLETSSSS 251 N S NS + ++S +S SS Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963 Score = 36.6 bits (83), Expect = 0.048 Identities = 34/164 (20%), Positives = 64/164 (39%), Gaps = 2/164 (1%) Query: 42 STESAQDTYLDSQD--HKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPK 99 S++S+ + DS D + S+ + S S+SS+S +SS S + + ++ + Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953 Query: 100 HAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDD 159 + S + +S S ++ S+ D + S ++ + Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013 Query: 160 WRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNS 203 S+ S SS SD+ D++DSS S D + NS Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057 Score = 36.2 bits (82), Expect = 0.063 Identities = 43/224 (19%), Positives = 80/224 (35%), Gaps = 6/224 (2%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 S++ + D+ S S+ +++S SNSSDS DSS S + + E+ Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 + S + S + +++ S D + + S ++ + + Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSS------DSSESSNSSDNSNSSDSSNSSDSSDSSD 949 Query: 161 RSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIK 220 S+ S SS SD+ D+N S S S +S S D+ + Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009 Query: 221 RNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264 + S NS + +S ++S SS + + + D Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053 Score = 35.8 bits (81), Expect = 0.082 Identities = 52/229 (22%), Positives = 81/229 (35%), Gaps = 7/229 (3%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS S DS D S +S S SNSSDS DSS S + + ++ + Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDS--SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 + S + +S S+ + SS S + S D Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073 Query: 161 RSSVPSHSMSSRRDTD----SDTQDANDSSCKSSERSLPDCTPHPNSI-SIDAGPRQAPK 215 SS S S S +D SD+ D++DSS S D + +S S D+ Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133 Query: 216 IAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264 + N S +S + ++S ++S SS + + + D Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182 Score = 35.4 bits (80), Expect = 0.11 Identities = 43/169 (25%), Positives = 61/169 (36%), Gaps = 5/169 (2%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS S DS D S+ + S SNSSDS DSS S + + ++ E Sbjct: 1096 SSDSSDSSDSSDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 + S + +S S + SS S + S D Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214 Query: 161 RSSVPSHSMSSRRDTDS----DTQDANDSSCKSSERSLPDCTPHPNSIS 205 SS S S S +DS D+ D++DSS S+ D + +S S Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263 Score = 34.7 bits (78), Expect = 0.18 Identities = 49/221 (22%), Positives = 79/221 (35%), Gaps = 8/221 (3%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS S DS D S+ +S S SNSSDS DSS S + + ++ Sbjct: 659 SSNSSNSSDSSDSSD-SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 ++ + + +S+ S + SS S + S D Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777 Query: 161 RSSVPSHSMSSRRDTDS-------DTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQA 213 SS S S S +DS D+ +++DSS S +S S D+ Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837 Query: 214 PKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAE 254 + + S G +SD + + S D + SS+ ++ Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878 Score = 34.3 bits (77), Expect = 0.24 Identities = 42/167 (25%), Positives = 59/167 (35%), Gaps = 5/167 (2%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS S DS D S+ + S SNSSDS DSS S + + ++ E Sbjct: 1030 SSDSSDSSDSSDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 + S + +S S + SS S + S D Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148 Query: 161 RSSVPSHSMSSRRDTDS----DTQDANDSSCKSSERSLPDCTPHPNS 203 SS S S S +DS D+ D++DSS S D + +S Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195 Score = 33.9 bits (76), Expect = 0.31 Identities = 47/226 (20%), Positives = 84/226 (37%), Gaps = 14/226 (6%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 +S++S+ + + S+ ++ S SNSSDS DSS S + + ++ Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 + S + +S S + + SS S + S D Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSS------------DSSNSSDSSDSSDSSDSSDSS 1109 Query: 161 RSSVPSHSMSSRRDTD-SDTQDANDSSCKSSERSLPDCTPHPNSI-SIDAGPRQAPKIAQ 218 SS S S S +D SD+ D++DSS S+ D + +S S D+ + Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169 Query: 219 IKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRD 264 + S NS + ++S ++S SS + + + D Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215 Score = 33.1 bits (74), Expect = 0.53 Identities = 35/157 (22%), Positives = 58/157 (36%), Gaps = 5/157 (3%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS S DS D S+ + S SNSSDS DSS S + + ++ + Sbjct: 1114 SSDSSDSSNSSDSSD-SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172 Query: 101 ----AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQV 156 ++ S+ + S +++ S D + S ++ Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232 Query: 157 EDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERS 193 E S S SS SD+ D++DS+ S++ S Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269 Score = 32.0 bits (71), Expect = 1.2 Identities = 37/150 (24%), Positives = 56/150 (37%), Gaps = 7/150 (4%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 SS S DS D SE + S S+SSDS DSS S + + ++ + Sbjct: 1132 SSDSSDSSNSSDSSD-SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190 Query: 101 AALKSEQGTLTSSESHP-EAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDD 159 + S + +S S +++ S D E S ++ D Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD-----SSD 1245 Query: 160 WRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189 +S S S D+ SD+ D +DS KS Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275 Score = 31.6 bits (70), Expect = 1.5 Identities = 44/212 (20%), Positives = 71/212 (33%), Gaps = 2/212 (0%) Query: 41 SSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKH 100 S ++ A+D DS + S +N +D D S + + + ++ Sbjct: 505 SDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSS 564 Query: 101 AALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDW 160 + S+ SS + SS D + S ++ S D Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD-SSDSSDSSDSK 623 Query: 161 RSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIK 220 S S S SS D+ SD+ D+N S + S +S S D+ + Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS 683 Query: 221 RNLS-YGDNSDPALEASSLPPPDPWLETSSSS 251 N S D+SD + + S D SS S Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 41.6 bits (96), Expect = 0.001 Identities = 40/136 (29%), Positives = 57/136 (41%), Gaps = 11/136 (8%) Query: 22 PPP-----VPPRTT-SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDS 75 PPP +PPR+ S PF V ++S+ + L + +E S ++ S D Sbjct: 2390 PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449 Query: 76 STRPPS--VTRGGVAPAPEAPEPPPKHAALKSEQGTLTS--SESHPEAAPKRKLSSIGIQ 131 +RPPS +R AP + P P P A K+ TS + P A P + + Sbjct: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK 2509 Query: 132 VDCIQPVPKEEPSPAT 147 V QP P SP T Sbjct: 2510 VPSGQP-PNFVRSPGT 2524 Score = 35.4 bits (80), Expect = 0.11 Identities = 65/287 (22%), Positives = 99/287 (34%), Gaps = 58/287 (20%) Query: 21 TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSN-SSDSLDSSTRP 79 +PPP R + P +S ES L +S + S S DS T P Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEESP----LSPPPEESPTSPPPEASRLSPPPEDSPTSP 700 Query: 80 PS-----------------VTRGGVAPAPEAPEPPPK----HAALKSEQGTLTSSESHPE 118 P + + P PE P+ P+ H + + E+ L+ P Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPH 760 Query: 119 AAPKRKLSSIGIQVD--CIQPVPKEEP-----------SPATKFQSIGVQVEDDWRSSVP 165 +P+ + + Q + C+ VP EEP SP + + Q E+ S VP Sbjct: 761 LSPQAEEPHLSPQPEEPCLCAVP-EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819 Query: 166 SHSMSSRRDTDSDTQDANDSSCKSS---------ERSLPDCTPHPNSISIDAGPRQAPKI 216 S + +S ++ C S E P +P P + P Q P Sbjct: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE--PGQCPAP 877 Query: 217 AQIKRNLSYGDNS------DPALEASSLPPPDPWLETSSSSPA-EPA 256 ++ G+ S +PAL PP P E SP+ EP+ Sbjct: 878 EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924 Score = 33.5 bits (75), Expect = 0.41 Identities = 56/246 (22%), Positives = 80/246 (32%), Gaps = 49/246 (19%) Query: 24 PVPPRTTSKPF-------ISVTVQSSTESAQDTYLDSQDHKSEVT---SQSGLSNSSDSL 73 P+ P S PF +S +S A +T L S ++ +S LS + L Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561 Query: 74 DSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVD 133 +S PP +R P PPP+ ES P+ + Sbjct: 562 PTSP-PPEASRLSPPPEESPMSPPPE--------------ESPMSPPPEASRLFPPFEES 606 Query: 134 CIQPVPKEEP-SPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSER 192 + P P+E P SP + + ED S P S S + S S Sbjct: 607 PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS---------PPPEVSRLSPLP 657 Query: 193 SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSP 252 + +P P + P ++P + P EAS L PP TS Sbjct: 658 VVSRLSPPPEESPLSPPPEESP--------------TSPPPEASRLSPPPEDSPTSPPPE 703 Query: 253 AEPAQP 258 PA P Sbjct: 704 DSPASP 709 Score = 32.7 bits (73), Expect = 0.69 Identities = 38/134 (28%), Positives = 51/134 (38%), Gaps = 22/134 (16%) Query: 86 GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPK-----RKLSSIGIQVDCIQPVPK 140 GV P P PE P AA SE + PE PK R S + PK Sbjct: 3088 GVEPGPLGPEERPPPAADASEP---RLASVLPEVKPKVEEGGRHPSPCQFTI----ATPK 3140 Query: 141 EEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPH 200 EP+PA +G++ P SM RDT T + SS ++E++ T Sbjct: 3141 VEPAPAANSLGLGLK---------PGQSMMGSRDTRMGTGPFS-SSGHTAEKASFGATGG 3190 Query: 201 PNSISIDAGPRQAP 214 P + + P P Sbjct: 3191 PPAHLLTPSPLSGP 3204 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 41.2 bits (95), Expect = 0.002 Identities = 54/252 (21%), Positives = 89/252 (35%), Gaps = 18/252 (7%) Query: 22 PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81 PPPVP T+ P + + ++ E + ++ ++ S+S D P + Sbjct: 853 PPPVP---TAVPTLCLPPEADAEPGRPK------KRAHSLNRYAASDSEPERDELLVPAA 903 Query: 82 V-------TRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDC 134 R G + + AP K+ + P PKR S++ Sbjct: 904 AGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLA 963 Query: 135 IQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSL 194 +PVP EP + D SV + S S + + + ++ + R Sbjct: 964 DEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRP 1023 Query: 195 PDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLP-PPDPWLETSSSSPA 253 P+ P P S + G R A +A +K + G + +L P L T+ P Sbjct: 1024 PEGHPTPRPASPEPG-RVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPG 1082 Query: 254 EPAQPGACRRDG 265 E A PG DG Sbjct: 1083 ESADPGPFVEDG 1094 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 40.8 bits (94), Expect = 0.003 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%) Query: 19 KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76 K+T V TT +K + Q+ST+ + T + E TS L+ +S L Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197 Query: 77 T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129 T + + T+G P+ P P P + A+ ++ T T+ +S P E AP S+ Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 255 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189 P +EP+P T + ++ ++ + ++ + + ++ ++ K Sbjct: 256 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308 Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249 + P P P + + P + A + + +PA A P P E + Sbjct: 309 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 366 Query: 250 SSPAEPA 256 ++P EPA Sbjct: 367 TTPKEPA 373 Score = 30.4 bits (67), Expect = 3.4 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%) Query: 21 TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79 TP P TT KP + + + + ++T + K T+ L+ ++ + T P Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512 Query: 80 ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129 P+ PE P P PK AA + E T E P E AP + Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187 P +EP+P T + ++ S + T Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632 Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247 ++ + TP + + P + L+ P S P P ET Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692 Query: 248 SSSSPAEPA 256 + ++P EPA Sbjct: 693 APTTPKEPA 701 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 40.8 bits (94), Expect = 0.003 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%) Query: 19 KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76 K+T V TT +K + Q+ST+ + T + E TS L+ +S L Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238 Query: 77 T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129 T + + T+G P+ P P P + A+ ++ T T+ +S P E AP S+ Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 296 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189 P +EP+P T + ++ ++ + ++ + + ++ ++ K Sbjct: 297 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349 Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249 + P P P + + P + A + + +PA A P P E + Sbjct: 350 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 407 Query: 250 SSPAEPA 256 ++P EPA Sbjct: 408 TTPKEPA 414 Score = 30.4 bits (67), Expect = 3.4 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%) Query: 21 TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79 TP P TT KP + + + + ++T + K T+ L+ ++ + T P Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553 Query: 80 ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129 P+ PE P P PK AA + E T E P E AP + Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187 P +EP+P T + ++ S + T Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673 Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247 ++ + TP + + P + L+ P S P P ET Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733 Query: 248 SSSSPAEPA 256 + ++P EPA Sbjct: 734 APTTPKEPA 742 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 40.8 bits (94), Expect = 0.003 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%) Query: 19 KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76 K+T V TT +K + Q+ST+ + T + E TS L+ +S L Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290 Query: 77 T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129 T + + T+G P+ P P P + A+ ++ T T+ +S P E AP S+ Sbjct: 291 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 348 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189 P +EP+P T + ++ ++ + ++ + + ++ ++ K Sbjct: 349 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401 Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249 + P P P + + P + A + + +PA A P P E + Sbjct: 402 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459 Query: 250 SSPAEPA 256 ++P EPA Sbjct: 460 TTPKEPA 466 Score = 30.4 bits (67), Expect = 3.4 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%) Query: 21 TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79 TP P TT KP + + + + ++T + K T+ L+ ++ + T P Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605 Query: 80 ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129 P+ PE P P PK AA + E T E P E AP + Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187 P +EP+P T + ++ S + T Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725 Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247 ++ + TP + + P + L+ P S P P ET Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785 Query: 248 SSSSPAEPA 256 + ++P EPA Sbjct: 786 APTTPKEPA 794 Score = 29.6 bits (65), Expect = 5.9 Identities = 48/270 (17%), Positives = 94/270 (34%), Gaps = 35/270 (12%) Query: 19 KKTPPPVPP----RTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD 74 KK PPP ++T+K + T+ ++ +++H +S S+SS S Sbjct: 76 KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS 135 Query: 75 SSTRPPSVTRGGVA---------------------PAPEAPEPPPKHAALKSEQGTLTSS 113 S+ R ++ A P P+ P + L + +T+ Sbjct: 136 STIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP 195 Query: 114 ESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRR 173 ++ K S I P P P+ T ++ ++ + + + + + Sbjct: 196 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 255 Query: 174 DTDSDTQDANDSSCKSSER-SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPA 232 TD + + +S E+ S D P ++ + PK + + +P Sbjct: 256 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-----KPTPKAETTTKGPALTTPKEPT 310 Query: 233 ----LEASSLPPPDPWLETSSSSPAEPAQP 258 E +S P +P T S+P P +P Sbjct: 311 PTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 40.8 bits (94), Expect = 0.003 Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 20/247 (8%) Query: 19 KKTPPPVPPRTT--SKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76 K+T V TT +K + Q+ST+ + T + E TS L+ +S L Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331 Query: 77 T-RPPSVTRGGVAPAPEAPEP--PPKHAALKSEQGTLTSSESHP----EAAPKRKLSSIG 129 T + + T+G P+ P P P + A+ ++ T T+ +S P E AP S+ Sbjct: 332 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-- 389 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKS 189 P +EP+P T + ++ ++ + ++ + + ++ ++ K Sbjct: 390 -------PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442 Query: 190 SERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSS 249 + P P P + + P + A + + +PA A P P E + Sbjct: 443 PAPTTPK-EPAPTTPK-EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500 Query: 250 SSPAEPA 256 ++P EPA Sbjct: 501 TTPKEPA 507 Score = 30.4 bits (67), Expect = 3.4 Identities = 50/249 (20%), Positives = 81/249 (32%), Gaps = 14/249 (5%) Query: 21 TPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRP- 79 TP P TT KP + + + + ++T + K T+ L+ ++ + T P Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646 Query: 80 ---PSVTRGGVAPAPEAPEPP-PKHAALKS--EQGTLTSSESHP----EAAPKRKLSSIG 129 P+ PE P P PK AA + E T E P E AP + Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706 Query: 130 IQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTD--SDTQDANDSSC 187 P +EP+P T + ++ S + T Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766 Query: 188 KSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLET 247 ++ + TP + + P + L+ P S P P ET Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826 Query: 248 SSSSPAEPA 256 + ++P EPA Sbjct: 827 APTTPKEPA 835 Score = 29.6 bits (65), Expect = 5.9 Identities = 48/270 (17%), Positives = 94/270 (34%), Gaps = 35/270 (12%) Query: 19 KKTPPPVPP----RTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLD 74 KK PPP ++T+K + T+ ++ +++H +S S+SS S Sbjct: 117 KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSS 176 Query: 75 SSTRPPSVTRGGVA---------------------PAPEAPEPPPKHAALKSEQGTLTSS 113 S+ R ++ A P P+ P + L + +T+ Sbjct: 177 STIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP 236 Query: 114 ESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRR 173 ++ K S I P P P+ T ++ ++ + + + + + Sbjct: 237 DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 296 Query: 174 DTDSDTQDANDSSCKSSER-SLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPA 232 TD + + +S E+ S D P ++ + PK + + +P Sbjct: 297 STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-----KPTPKAETTTKGPALTTPKEPT 351 Query: 233 ----LEASSLPPPDPWLETSSSSPAEPAQP 258 E +S P +P T S+P P +P Sbjct: 352 PTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 40.8 bits (94), Expect = 0.003 Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 40/215 (18%) Query: 27 PRTTSKPFISVTV-QSSTESAQDTYLDSQDHKSEVTS---QSGLSNSSDSLDSSTRPPSV 82 P S+ SVT Q +++ T+ +SQ S + Q S SDS + +PPS Sbjct: 388 PTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSS 447 Query: 83 TRGGVAPAPEAPE--PPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPK 140 + AP P AP+ P P +A S + ++S+S + + + SS + + P Sbjct: 448 S----AP-PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPA 502 Query: 141 EEPSPAT--KFQSIGVQVEDDWRSSV-------------------PSHSMSSRRDTDSDT 179 EP P T K+Q D+W + V P SS T + Sbjct: 503 PEPEPPTTNKWQL------DNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEH 556 Query: 180 QDANDSSCKSSERS--LPDCTPHPNSISIDAGPRQ 212 ++ D KSS ++ P PHP S P Q Sbjct: 557 SESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQ 591 >gi|82830424 gon-4-like isoform a [Homo sapiens] Length = 2240 Score = 40.0 bits (92), Expect = 0.004 Identities = 47/192 (24%), Positives = 73/192 (38%), Gaps = 26/192 (13%) Query: 48 DTYLDSQDHKS--EVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKS 105 DT S++ S EVT Q+ L + + P S + EPP Sbjct: 1357 DTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSS-----------SQEPP-------- 1397 Query: 106 EQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVP 165 ++GT S + + K LSS+ +V P K E S + QS+G V + Sbjct: 1398 DEGT--SGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKN 1455 Query: 166 SHSMSSRRDTDSDTQDANDSSCKSSER---SLPDCTPHPNSISIDAGPRQAPKIAQIKRN 222 D D TQD D +SE S+P+ ++ A R+ + + + Sbjct: 1456 GPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEE 1515 Query: 223 LSYGDNSDPALE 234 S +NS+P E Sbjct: 1516 NSQEENSEPEEE 1527 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 39.7 bits (91), Expect = 0.006 Identities = 51/240 (21%), Positives = 88/240 (36%), Gaps = 20/240 (8%) Query: 22 PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81 P P+PP+ KP +++ +ST++ + V +Q+ + + + + P+ Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTV-----------APVVTQAAPPTPTPPVPPAKKQPA 818 Query: 82 VTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE 141 + P+P P P L +Q S + P +P + S+ Q+ P P Sbjct: 819 FPASYIPPSPPTPPVPVPPPTLPKQQ----SFCAKPPPSPLSPVPSVVKQIASQFPPP-- 872 Query: 142 EPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHP 201 PA + Q + + S P+ + S + D E SL P P Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932 Query: 202 NSISIDAGPRQAPKIAQIKRNLSYG-DNSDPALEASSLPPPDPWLETS--SSSPAEPAQP 258 + + P ++ S G S + PPP P +S SSS AE +P Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992 Score = 33.5 bits (75), Expect = 0.41 Identities = 35/136 (25%), Positives = 47/136 (34%), Gaps = 17/136 (12%) Query: 22 PPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81 PPP PP P + S SA ++ S +T S S +L PP Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY----STITRLQNASQHSGALFKPPTPPV 691 Query: 82 -----------VTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPE-AAPKRKLSSIG 129 V GV P P P PPP + ++ + S P+ +AP L Sbjct: 692 MQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQ 751 Query: 130 IQVDCIQPVPKEEPSP 145 +Q Q P P P Sbjct: 752 VQ-HITQVAPPTPPPP 766 Score = 31.6 bits (70), Expect = 1.5 Identities = 33/130 (25%), Positives = 45/130 (34%), Gaps = 6/130 (4%) Query: 16 VAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQS---GLSNSSDS 72 +A + PPP PP S+P V + +S + S + S S Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924 Query: 73 LDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSE--SHPEAAPKRKLSSIGI 130 L PPS P P P P + ++ + TSS P P+R SSI Sbjct: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN-SSIKS 983 Query: 131 QVDCIQPVPK 140 P PK Sbjct: 984 SSGAEHPEPK 993 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 39.7 bits (91), Expect = 0.006 Identities = 52/239 (21%), Positives = 83/239 (34%), Gaps = 21/239 (8%) Query: 23 PPVPPRTTSKPFISVTVQSSTESAQ-DTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPS 81 P P + P S+ ++S +SA L S++ S + SQ LS + S PP Sbjct: 1324 PEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPS-----NPP- 1377 Query: 82 VTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE 141 G PAP AP PP A + TS+ P + + G + Sbjct: 1378 ----GAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETS 1433 Query: 142 EPSPATKFQSIGVQ-VEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPH 200 +P T + VQ + P+ +S RD + + + P+ +PH Sbjct: 1434 QPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA--------PEPSPH 1485 Query: 201 PNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPG 259 + G + AP + +S + P+ PP P S P + G Sbjct: 1486 SGTPQPALG-QPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVG 1543 Score = 32.7 bits (73), Expect = 0.69 Identities = 48/190 (25%), Positives = 71/190 (37%), Gaps = 21/190 (11%) Query: 36 SVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPE 95 S+T +SS S D + S+ + + R R G + E Sbjct: 1643 SMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAE 1702 Query: 96 PPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPA-TKFQSIGV 154 PPP S+ GT+ SHP+ R L S +P ++ SPA T + V Sbjct: 1703 PPP------SDMGTVGGQASHPQTLGARALGS-----PRKRPEQQDVSSPAKTVGRFSVV 1751 Query: 155 QVEDDWRSSVPSHSMSSRRDTDSDTQDANDS-SCKSSER------SLPDCTPHP-NSISI 206 +D+W + P HS+ D +A S K + R S+ P +S S Sbjct: 1752 STQDEWTLASP-HSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSG 1810 Query: 207 DAGPRQAPKI 216 D GPR P + Sbjct: 1811 DEGPRARPPV 1820 >gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapiens] Length = 729 Score = 39.3 bits (90), Expect = 0.007 Identities = 105/470 (22%), Positives = 181/470 (38%), Gaps = 75/470 (15%) Query: 37 VTVQSSTESAQ-DTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAP---APE 92 ++VQ TE +L+ + +S + S L+ + S ++ P V G V+ +P Sbjct: 257 LSVQQETEDQNYGIFLEMMEARSRGHA-SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG 315 Query: 93 APEPPPK---HAALKSEQGTLTSSESHPEAA------PKRKLSS--IGIQVDCIQPVPKE 141 P+P P+ +AA S + SE+ P A P+R + S G P Sbjct: 316 TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPP 375 Query: 142 EPSPATK----FQSIGVQVEDD------WRSSVPSH------SMSSRRDTDSDTQDANDS 185 EP PA + QS+ V DD + P+ + ++++D+DSD + + Sbjct: 376 EPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGN 435 Query: 186 SCKSSERSLPDCTPHPN-SISIDAGP-----------RQAPKIAQIKRNLSYGDN-SDPA 232 + + D P S + AGP +A A K S+P Sbjct: 436 PMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPE 495 Query: 233 LEASSLPPPDPWLETSSSSPAEPAQPGACR-RDGYWFLKLLQ--AETERLEGWCCQMDKE 289 + SS+P P T+ + A P PG R G + AE E +G + Sbjct: 496 TKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSES 555 Query: 290 TKENNLSEEVLGKVLS-----AVGSAQLLMSQKF---QQFRGLCEQNLNPDANPRPTAQD 341 E ++ ++L V+ + GS + F + +++ P P P Sbjct: 556 DPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLP 615 Query: 342 LAGFW-----DLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAK 396 L F DL L +E+ K + + +TP K K++KK ++ A Sbjct: 616 LPAFRLKNDSDLFGLGLEEAGPKES------SEEGKEGKTPSKEKKKKKKKGKEEEEKAA 669 Query: 397 SKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYV 446 K S+ K S ++ ++E R+R +R R+ +A AD +E ++ Sbjct: 670 KKK--SKHKKSKDKEEGKEERRRR---QQRPPRSRERTA---ADELEAFL 711 >gi|194272142 myosin IXB isoform 2 [Homo sapiens] Length = 2022 Score = 39.3 bits (90), Expect = 0.007 Identities = 82/355 (23%), Positives = 129/355 (36%), Gaps = 68/355 (19%) Query: 88 APAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE----EP 143 AP+PE PP K A +S + + SS E+ +R L + Q IQ +E EP Sbjct: 1120 APSPEKTLPPQKTVAAESHE-KVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREP 1178 Query: 144 SPATKFQSIGVQVEDDWRSS----------VPSHSMSSRRDTDSDTQDANDSSCKSSERS 193 S Q GV + +D + S + + S ++ T+ A + +E++ Sbjct: 1179 SRRVT-QEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKT 1237 Query: 194 LPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPA 253 LP +P P Q++R S AL+ S + PP P ++ +P Sbjct: 1238 LPSGSPRP---------------GQLERPTSL------ALD-SRVSPPAP--GSAPETPE 1273 Query: 254 EPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEV---LGKVLSAVGSA 310 + ++P R E G Q+ + L+ V GK L A S Sbjct: 1274 DKSKPCGSPR---------VQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVAAASP 1324 Query: 311 QLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANS 370 ++SQ L +++ A PT + F S D+S L A + Sbjct: 1325 SAMLSQSLD----LSDRHRATGAALTPTEERRTSF------STSDVSKLLPSL----AKA 1370 Query: 371 WQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAK 425 ET + + KK P V KK ++ S S + KRL K Sbjct: 1371 QPAAETTDGERSAKK--PAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHK 1423 >gi|33356170 myosin IXB isoform 1 [Homo sapiens] Length = 2157 Score = 39.3 bits (90), Expect = 0.007 Identities = 82/355 (23%), Positives = 129/355 (36%), Gaps = 68/355 (19%) Query: 88 APAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKE----EP 143 AP+PE PP K A +S + + SS E+ +R L + Q IQ +E EP Sbjct: 1120 APSPEKTLPPQKTVAAESHE-KVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREP 1178 Query: 144 SPATKFQSIGVQVEDDWRSS----------VPSHSMSSRRDTDSDTQDANDSSCKSSERS 193 S Q GV + +D + S + + S ++ T+ A + +E++ Sbjct: 1179 SRRVT-QEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKT 1237 Query: 194 LPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPA 253 LP +P P Q++R S AL+ S + PP P ++ +P Sbjct: 1238 LPSGSPRP---------------GQLERPTSL------ALD-SRVSPPAP--GSAPETPE 1273 Query: 254 EPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEV---LGKVLSAVGSA 310 + ++P R E G Q+ + L+ V GK L A S Sbjct: 1274 DKSKPCGSPR---------VQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVAAASP 1324 Query: 311 QLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANS 370 ++SQ L +++ A PT + F S D+S L A + Sbjct: 1325 SAMLSQSLD----LSDRHRATGAALTPTEERRTSF------STSDVSKLLPSL----AKA 1370 Query: 371 WQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAK 425 ET + + KK P V KK ++ S S + KRL K Sbjct: 1371 QPAAETTDGERSAKK--PAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHK 1423 >gi|193083172 nuclear assembly factor 1 homolog isoform b [Homo sapiens] Length = 389 Score = 39.3 bits (90), Expect = 0.007 Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 15/132 (11%) Query: 86 GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPV------- 138 GV P AP P A + Q L S E P+A ++ G Q +QPV Sbjct: 22 GVGEGPAAPSPGS--APVPGTQPPLQSFEGSPDAGQTVEVKPAGEQP--LQPVLNAVAAG 77 Query: 139 -PKEEPSPATKFQSIGVQVEDDWRSS---VPSHSMSSRRDTDSDTQDANDSSCKSSERSL 194 P +P P + + G V + P +S D+DSD++ +DSS SS S Sbjct: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 Query: 195 PDCTPHPNSISI 206 + + IS+ Sbjct: 138 SSSSSSSSCISL 149 >gi|193083157 nuclear assembly factor 1 homolog isoform a [Homo sapiens] Length = 494 Score = 39.3 bits (90), Expect = 0.007 Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 15/132 (11%) Query: 86 GVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPV------- 138 GV P AP P A + Q L S E P+A ++ G Q +QPV Sbjct: 22 GVGEGPAAPSPGS--APVPGTQPPLQSFEGSPDAGQTVEVKPAGEQP--LQPVLNAVAAG 77 Query: 139 -PKEEPSPATKFQSIGVQVEDDWRSS---VPSHSMSSRRDTDSDTQDANDSSCKSSERSL 194 P +P P + + G V + P +S D+DSD++ +DSS SS S Sbjct: 78 TPAPQPQPPAESPACGDCVTSPGAAEPARAPDSLETSDSDSDSDSETDSDSSSSSSSSSS 137 Query: 195 PDCTPHPNSISI 206 + + IS+ Sbjct: 138 SSSSSSSSCISL 149 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 39.3 bits (90), Expect = 0.007 Identities = 59/254 (23%), Positives = 93/254 (36%), Gaps = 58/254 (22%) Query: 22 PPPVPPR-----TTSKPFISVTVQSSTESA-QDTYLDSQDH--KSEVTSQSGLSNSSDSL 73 PPP PP T+S+P++ S ++S +YL S +SQS LS+S L Sbjct: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYL 225 Query: 74 DSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHP-EAAPKRKLSSIGIQV 132 SS PS G + + PPP + G T+ + P E+ K K Sbjct: 226 PSSQASPSRPSQGHSKSQLLAPPPP-----SAPPGNKTTVQQEPLESGAKNK------ST 274 Query: 133 DCIQPVPKEEPSPATK-------FQSIGVQVEDDWRSSVPSHSMSS--RRDTDSDTQDAN 183 + Q P+ +PS T ++ + ++ + +P H +DT ++ Sbjct: 275 EQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKE-- 332 Query: 184 DSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDP 243 E ++P + P S S + P P +PPP P Sbjct: 333 -------EVTVPATSQVPESPSSEEPPLPPPN--------------------EEVPPPLP 365 Query: 244 WLETSSSSPAEPAQ 257 E S P E A+ Sbjct: 366 PEEPQSEDPEEDAR 379 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.124 0.358 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,323,524 Number of Sequences: 37866 Number of extensions: 1141561 Number of successful extensions: 11845 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 86 Number of HSP's successfully gapped in prelim test: 497 Number of HSP's that attempted gapping in prelim test: 9633 Number of HSP's gapped (non-prelim): 2639 length of query: 453 length of database: 18,247,518 effective HSP length: 106 effective length of query: 347 effective length of database: 14,233,722 effective search space: 4939101534 effective search space used: 4939101534 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.