BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33286446 opioid growth factor receptor [Homo sapiens] (677 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33286446 opioid growth factor receptor [Homo sapiens] 1413 0.0 gi|55770902 opioid growth factor receptor-like 1 [Homo sapiens] 273 4e-73 gi|150170670 piccolo isoform 2 [Homo sapiens] 91 3e-18 gi|150378539 piccolo isoform 1 [Homo sapiens] 91 3e-18 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 89 1e-17 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 88 2e-17 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 85 3e-16 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 82 1e-15 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 82 1e-15 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 82 1e-15 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 81 4e-15 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 80 8e-15 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 80 8e-15 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 80 8e-15 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 80 8e-15 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 79 2e-14 gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-ch... 79 2e-14 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 77 4e-14 gi|110832843 TBP-associated factor 4 [Homo sapiens] 77 7e-14 gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] 77 7e-14 gi|157074225 nuclear pore complex interacting protein-like 3 [Ho... 76 9e-14 gi|139394646 iroquois homeobox protein 5 [Homo sapiens] 75 2e-13 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 75 3e-13 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 74 3e-13 gi|48762934 alpha 2 type I collagen [Homo sapiens] 74 4e-13 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 74 4e-13 gi|163965366 nascent polypeptide-associated complex alpha subuni... 73 8e-13 gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 72 2e-12 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 71 3e-12 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 71 3e-12 >gi|33286446 opioid growth factor receptor [Homo sapiens] Length = 677 Score = 1413 bits (3658), Expect = 0.0 Identities = 677/677 (100%), Positives = 677/677 (100%) Query: 1 MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRM 60 MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRM Sbjct: 1 MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRM 60 Query: 61 TGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDN 120 TGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDN Sbjct: 61 TGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDN 120 Query: 121 YDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGI 180 YDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGI Sbjct: 121 YDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGI 180 Query: 181 RLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEET 240 RLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEET Sbjct: 181 RLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEET 240 Query: 241 LVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSL 300 LVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSL Sbjct: 241 LVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSL 300 Query: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLER 360 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLER Sbjct: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLER 360 Query: 361 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALS 420 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALS Sbjct: 361 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALS 420 Query: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA 480 QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA Sbjct: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA 480 Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE Sbjct: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540 Query: 541 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSE 600 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSE Sbjct: 541 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSE 600 Query: 601 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA 660 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA Sbjct: 601 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA 660 Query: 661 AELQDAEVESSAKSGKP 677 AELQDAEVESSAKSGKP Sbjct: 661 AELQDAEVESSAKSGKP 677 >gi|55770902 opioid growth factor receptor-like 1 [Homo sapiens] Length = 451 Score = 273 bits (698), Expect = 4e-73 Identities = 161/424 (37%), Positives = 233/424 (54%), Gaps = 43/424 (10%) Query: 5 DCDSTWEEDEEDAEDA-------------EDEDCEDGEAAGARDADAGDEDEESEEPRAA 51 DCDSTW+ D E + ++ + E AG R + DE++E A Sbjct: 18 DCDSTWQTDSEPEPEEPGPGGGSEGPGQESEQPAQPPEQAGGRPGASPAPDEDAEAAGAE 77 Query: 52 RPS-SFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFI 110 + S ++ R++ A RD+ +YRH YP+ + D NL FY+N+I F P+G +I Sbjct: 78 QGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYI 137 Query: 111 EDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRA 170 E++L W +Y+ LE NH+YIQWLFPLRE G+N++AK LT E+E FK ++E R + A Sbjct: 138 EEVLSKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLA 197 Query: 171 YELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQA 230 Y++ML F+GI+L D+ TG V RA N+Q+RFQ+LN HN LRITRILKSLGELG E F++ Sbjct: 198 YKMMLEFFGIKLTDK-TGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKS 256 Query: 231 PLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQD 290 PLV+F L E LV +P ++QSAL+YF++ +R R +RR+L+ FA +H+ P F+WGP Sbjct: 257 PLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPR 316 Query: 291 KLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRV---DEGPQP 347 K EGS K ++ SP H + T + V + + Sbjct: 317 K----------EQSEGS-KAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAED 365 Query: 348 RSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKE-SKKRKLEL-SRREQPPTEPGPQSAS 405 + V P++ P+E + DRP P E +K R E S E ++P + Sbjct: 366 KKVAPKE--PVEET----------DRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTT 413 Query: 406 EVEK 409 EK Sbjct: 414 PTEK 417 Score = 37.4 bits (85), Expect = 0.046 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 5/60 (8%) Query: 504 TEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 563 T+ P+E PG SE PG ++PA+ P + G A PA DE AE+ G Sbjct: 25 TDSEPEPEEPGPGGGSEGPGQE-----SEQPAQPPEQAGGRPGASPAPDEDAEAAGAEQG 79 Score = 36.2 bits (82), Expect = 0.10 Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 15/94 (15%) Query: 583 GPSPAGPTRDEPAESPSET---PGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 639 G S PT E +S +T P P GP G SE PG ++PA+ P Sbjct: 7 GVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGG------SEGPGQE-----SEQPAQPPE 55 Query: 640 ETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAK 673 + G A P DE A+A A + D+ E++AK Sbjct: 56 QAGGRPGASPAPDEDAEAAGAEQGGDS-TEATAK 88 Score = 32.3 bits (72), Expect = 1.5 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 12/72 (16%) Query: 552 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAG 611 D ++ SE P P GP G SE PG ++PA+ P + G A PA Sbjct: 20 DSTWQTDSE-PEPEEPGPGGG------SEGPGQES-----EQPAQPPEQAGGRPGASPAP 67 Query: 612 DEPAESPSETPG 623 DE AE+ G Sbjct: 68 DEDAEAAGAEQG 79 Score = 32.3 bits (72), Expect = 1.5 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 11/62 (17%) Query: 522 PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 581 P P GP G SE PG ++PA+ P + G A PA DE AE+ Sbjct: 29 PEPEEPGPGGG------SEGPGQE-----SEQPAQPPEQAGGRPGASPAPDEDAEAAGAE 77 Query: 582 PG 583 G Sbjct: 78 QG 79 Score = 32.0 bits (71), Expect = 1.9 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 14/84 (16%) Query: 523 GPSPAGPAGDEPAESPSET---PGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 579 G S P E +S +T P P GP G SE PG ++PA+ P Sbjct: 7 GVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGG------SEGPGQE-----SEQPAQPPE 55 Query: 580 ETPGPSPAGPTRDEPAESPSETPG 603 + G A P DE AE+ G Sbjct: 56 QAGGRPGASPAPDEDAEAAGAEQG 79 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 91.3 bits (225), Expect = 3e-18 Identities = 91/390 (23%), Positives = 151/390 (38%), Gaps = 36/390 (9%) Query: 320 DHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGED-RPEPLS 378 D EAS + T + + EG ++ Q P+ + QG +D P+ +S Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240 Query: 379 PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCA--LSQGSLRTGTQEVGGQDP 436 ++ +K K + +P P ++ K+ L + Q + G + V P Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG-ESVKPSLP 299 Query: 437 GEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALA-----------GSP 485 + P +QP + + K G A SG + LA G+ Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359 Query: 486 APSGHP----KAGHSENGVEEDTEGRTGPKE-----GTPGSPSETPGPSPAG-------- 528 P P K + G E+ + + GPK G +P++ PGP+ Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419 Query: 529 PAGDEPA-ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587 P +P +SP++ PGP P + P++ GP P + PS+ PGP+ Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP 479 Query: 588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647 P + PA+ P + PG A P +P + P PA P+ +P + + P A Sbjct: 480 PPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537 Query: 648 GPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 P+ +P+ A +A+ Q + S SGKP Sbjct: 538 KPSAQQPSPAKPSAQ-QSTKPVSQTGSGKP 566 Score = 77.8 bits (190), Expect = 3e-14 Identities = 84/370 (22%), Positives = 142/370 (38%), Gaps = 36/370 (9%) Query: 306 GSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERS---- 361 G ++++G+P + + ++ P G G+ +GP PL+R Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPP----GTGKPIQGPTQTPQTDHAKLPLQRDASRP 281 Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG-----PQSASEVEKIALNLEG 416 Q +A + +P P SK + + + P +PG P A + + + Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341 Query: 417 CALSQGSLRTGTQEVGG-QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGG 475 A G+++ Q G + P + + P + P ++K + + V Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP 401 Query: 476 AQTLALAGSPAPS-GHPKAGHSENGVEEDTEG----RTGPKEGTPGS-PSETPGPSPAGP 529 AQ A P G PK + G++ + +T ++ PG P++ GP Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461 Query: 530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPSPA 587 P + PS+ PGP P PA+ P + PG A P +P + P + PGP+ Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKP 519 Query: 588 GPTRDEPAESPSETPG--------PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 639 P + + PS+ PG P PA P+ + + S+T +P P P SPS Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP----PTVSPS 575 Query: 640 ETPGPSPAGP 649 PS P Sbjct: 576 AKQPPSQGLP 585 Score = 45.1 bits (105), Expect = 2e-04 Identities = 84/356 (23%), Positives = 123/356 (34%), Gaps = 59/356 (16%) Query: 345 PQPRSVEPQ-DAGPLERSQGDEAGGHGEDRPEPL--------SPKESKKRKLELSR--RE 393 PQP+ P+ DA P + D + +P PL SP K+ E + Sbjct: 677 PQPQQTSPKKDAAPKQ----DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732 Query: 394 QPPTEPGPQSASEVEKIA---------LNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR 444 PP EP S + +A + +S S T + +A + Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792 Query: 445 QPLGARVADKVRKRRKVDEGAG--DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEE 502 PL A + E DS A+ + + ++ P PS K + V++ Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS-HPGPSSESKGQKQVDPVQK 851 Query: 503 DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSET 561 E + K T SP P P G SP+ PGPRP AG P +SP Sbjct: 852 KEEPK---KAQTKMSPKPDAKPMPKG--------SPTP-PGPRPTAGQTVPTPQQSPKPQ 899 Query: 562 PGPRP----AGPAGDEPAESPSETPGPSPAGPTRDEPAE---------SPSETPGPRPAG 608 R G D P P+ TP + G A S + PGP Sbjct: 900 EQSRRFSLNLGSITDAPKSQPT-TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958 Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQ 664 G ++P+ + P GP P + P P+ + P + E KA A +L+ Sbjct: 959 GPGAPMKQAPAPSQPPTSQGP----PKSTGQAPPAPAKSIPVKKE-TKAPAAEKLE 1009 Score = 37.4 bits (85), Expect = 0.046 Identities = 44/193 (22%), Positives = 73/193 (37%), Gaps = 15/193 (7%) Query: 478 TLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAES 537 T + +P + + ++D PK+ P T SP+ A P Sbjct: 668 TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727 Query: 538 PSETPGP--RPAGPAGDEPAESPSETP-GPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594 P P P+ P+ + A + P P+ P D + S + T P+ + + Sbjct: 728 SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787 Query: 595 AES---PSETPGPRPA---GPAGDEPAESPSETPGPRPAGPAG--DEPAESPSETPGPSP 646 E P +T +P+ P G++ + S+ PRPA + P S SE+ G Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI-PRPASDSKIISHPGPS-SESKGQKQ 845 Query: 647 AGPT--RDEPAKA 657 P ++EP KA Sbjct: 846 VDPVQKKEEPKKA 858 Score = 32.7 bits (73), Expect = 1.1 Identities = 60/284 (21%), Positives = 94/284 (33%), Gaps = 39/284 (13%) Query: 345 PQPRSVEPQDAGPLERSQGDEAGGHGEDRPEP----LSPKESKKRKLELSR--REQPPTE 398 P + + Q+ LE+ D+A E +P P L P+E K R E E+ PT Sbjct: 1187 PMVTTDQKQEESKLEK---DKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTP 1243 Query: 399 PGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKR 458 + E + A + L + ++ +++ G+ + VQ +QP K Sbjct: 1244 EDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ--------TKM 1295 Query: 459 RKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSP 518 + G S T + P P K E G E+ + + P Sbjct: 1296 EGLPSGTPQSLP-KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP 1354 Query: 519 SETPGPSPAGPAGDEPAESPSETPG---------------------PRPAGPAGDEPAES 557 G S G + D + S E P P+ P+ ES Sbjct: 1355 KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414 Query: 558 PSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET 601 + A DE +E ++ SP P E +S SET Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458 Score = 31.6 bits (70), Expect = 2.5 Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 569 PAGDEPAESPSETPGPSPAGP-TRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 627 PA P+ SPS + P+ P R + ++ P P P P P P P P P Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431 Query: 628 GP 629 P Sbjct: 2432 SP 2433 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 91.3 bits (225), Expect = 3e-18 Identities = 91/390 (23%), Positives = 151/390 (38%), Gaps = 36/390 (9%) Query: 320 DHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGED-RPEPLS 378 D EAS + T + + EG ++ Q P+ + QG +D P+ +S Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240 Query: 379 PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCA--LSQGSLRTGTQEVGGQDP 436 ++ +K K + +P P ++ K+ L + Q + G + V P Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG-ESVKPSLP 299 Query: 437 GEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALA-----------GSP 485 + P +QP + + K G A SG + LA G+ Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359 Query: 486 APSGHP----KAGHSENGVEEDTEGRTGPKE-----GTPGSPSETPGPSPAG-------- 528 P P K + G E+ + + GPK G +P++ PGP+ Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419 Query: 529 PAGDEPA-ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587 P +P +SP++ PGP P + P++ GP P + PS+ PGP+ Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP 479 Query: 588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647 P + PA+ P + PG A P +P + P PA P+ +P + + P A Sbjct: 480 PPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537 Query: 648 GPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 P+ +P+ A +A+ Q + S SGKP Sbjct: 538 KPSAQQPSPAKPSAQ-QSTKPVSQTGSGKP 566 Score = 77.8 bits (190), Expect = 3e-14 Identities = 84/370 (22%), Positives = 142/370 (38%), Gaps = 36/370 (9%) Query: 306 GSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERS---- 361 G ++++G+P + + ++ P G G+ +GP PL+R Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPP----GTGKPIQGPTQTPQTDHAKLPLQRDASRP 281 Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG-----PQSASEVEKIALNLEG 416 Q +A + +P P SK + + + P +PG P A + + + Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341 Query: 417 CALSQGSLRTGTQEVGG-QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGG 475 A G+++ Q G + P + + P + P ++K + + V Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP 401 Query: 476 AQTLALAGSPAPS-GHPKAGHSENGVEEDTEG----RTGPKEGTPGS-PSETPGPSPAGP 529 AQ A P G PK + G++ + +T ++ PG P++ GP Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461 Query: 530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPSPA 587 P + PS+ PGP P PA+ P + PG A P +P + P + PGP+ Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKP 519 Query: 588 GPTRDEPAESPSETPG--------PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 639 P + + PS+ PG P PA P+ + + S+T +P P P SPS Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP----PTVSPS 575 Query: 640 ETPGPSPAGP 649 PS P Sbjct: 576 AKQPPSQGLP 585 Score = 45.1 bits (105), Expect = 2e-04 Identities = 84/356 (23%), Positives = 123/356 (34%), Gaps = 59/356 (16%) Query: 345 PQPRSVEPQ-DAGPLERSQGDEAGGHGEDRPEPL--------SPKESKKRKLELSR--RE 393 PQP+ P+ DA P + D + +P PL SP K+ E + Sbjct: 677 PQPQQTSPKKDAAPKQ----DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732 Query: 394 QPPTEPGPQSASEVEKIA---------LNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR 444 PP EP S + +A + +S S T + +A + Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792 Query: 445 QPLGARVADKVRKRRKVDEGAG--DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEE 502 PL A + E DS A+ + + ++ P PS K + V++ Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS-HPGPSSESKGQKQVDPVQK 851 Query: 503 DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSET 561 E + K T SP P P G SP+ PGPRP AG P +SP Sbjct: 852 KEEPK---KAQTKMSPKPDAKPMPKG--------SPTP-PGPRPTAGQTVPTPQQSPKPQ 899 Query: 562 PGPRP----AGPAGDEPAESPSETPGPSPAGPTRDEPAE---------SPSETPGPRPAG 608 R G D P P+ TP + G A S + PGP Sbjct: 900 EQSRRFSLNLGSITDAPKSQPT-TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958 Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQ 664 G ++P+ + P GP P + P P+ + P + E KA A +L+ Sbjct: 959 GPGAPMKQAPAPSQPPTSQGP----PKSTGQAPPAPAKSIPVKKE-TKAPAAEKLE 1009 Score = 37.4 bits (85), Expect = 0.046 Identities = 44/193 (22%), Positives = 73/193 (37%), Gaps = 15/193 (7%) Query: 478 TLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAES 537 T + +P + + ++D PK+ P T SP+ A P Sbjct: 668 TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727 Query: 538 PSETPGP--RPAGPAGDEPAESPSETP-GPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594 P P P+ P+ + A + P P+ P D + S + T P+ + + Sbjct: 728 SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787 Query: 595 AES---PSETPGPRPA---GPAGDEPAESPSETPGPRPAGPAG--DEPAESPSETPGPSP 646 E P +T +P+ P G++ + S+ PRPA + P S SE+ G Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI-PRPASDSKIISHPGPS-SESKGQKQ 845 Query: 647 AGPT--RDEPAKA 657 P ++EP KA Sbjct: 846 VDPVQKKEEPKKA 858 Score = 32.7 bits (73), Expect = 1.1 Identities = 60/284 (21%), Positives = 94/284 (33%), Gaps = 39/284 (13%) Query: 345 PQPRSVEPQDAGPLERSQGDEAGGHGEDRPEP----LSPKESKKRKLELSR--REQPPTE 398 P + + Q+ LE+ D+A E +P P L P+E K R E E+ PT Sbjct: 1187 PMVTTDQKQEESKLEK---DKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTP 1243 Query: 399 PGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKR 458 + E + A + L + ++ +++ G+ + VQ +QP K Sbjct: 1244 EDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ--------TKM 1295 Query: 459 RKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSP 518 + G S T + P P K E G E+ + + P Sbjct: 1296 EGLPSGTPQSLP-KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP 1354 Query: 519 SETPGPSPAGPAGDEPAESPSETPG---------------------PRPAGPAGDEPAES 557 G S G + D + S E P P+ P+ ES Sbjct: 1355 KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414 Query: 558 PSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET 601 + A DE +E ++ SP P E +S SET Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458 Score = 31.6 bits (70), Expect = 2.5 Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 569 PAGDEPAESPSETPGPSPAGP-TRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 627 PA P+ SPS + P+ P R + ++ P P P P P P P P P Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431 Query: 628 GP 629 P Sbjct: 2432 SP 2433 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 89.0 bits (219), Expect = 1e-17 Identities = 73/218 (33%), Positives = 95/218 (43%), Gaps = 28/218 (12%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSE 540 GSP P+G PK E G + G G K G+PGSP P GPAG + P Sbjct: 512 GSPGPAG-PKGSPGEAGRPGEA-GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569 Query: 541 TPG----------PRPAGPAGDEPAESPSETPGPRPA-GPAGDEPAESPSETPGPSPAGP 589 PG P P G AG+ PGP A GPAG + E+ ++ P P PAGP Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD-GEAGAQGP-PGPAGP 627 Query: 590 TRDEPAESPSETPG----PRPAGPAGD--EPAES--PSETPGPRPAGPAGDE--PAESPS 639 + + P+ +PG P PAGP G+ +P E P + P P+G G+ P E Sbjct: 628 AGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGV 687 Query: 640 ETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 + P P PAGP A + A+ + G P Sbjct: 688 QGP-PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724 Score = 75.9 bits (185), Expect = 1e-13 Identities = 112/383 (29%), Positives = 134/383 (34%), Gaps = 47/383 (12%) Query: 306 GSRKVEEEGSPGDPD-HEASTQGRTCGPEHSKGGGRVDEGPQ----PRSVEPQDAGPLER 360 G+ E E P PD E+ T T G E KG D GP+ P +D P + Sbjct: 83 GAEVPEGECCPVCPDGSESPTDQETTGVEGPKG----DTGPRGPRGPAGPPGRDGIPGQP 138 Query: 361 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTE-PGPQSASEVEKIALNLEGCAL 419 G G P L + + + PGP S G Sbjct: 139 GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS-------GPRGLPG 191 Query: 420 SQGSLRTGTQEVGGQDPGEAVQP-CRQPLGARVADKVRKRRKVDEGAG------DSAAVA 472 G+ G Q G PGE +P P+G R + D AG + Sbjct: 192 PPGA--PGPQGFQGP-PGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248 Query: 473 SGGAQTL-ALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAG 531 GA+ L AG P GH G S + G GPK G PGSP E P GP G Sbjct: 249 PQGARGLPGTAGLPGMKGH--RGFSGLDGAKGDAGPAGPK-GEPGSPGENGAPGQMGPRG 305 Query: 532 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPT 590 PG PAG G++ A + PGP PAGP G A GP GP Sbjct: 306 LPGERGRPGAPG--PAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ--GPR 361 Query: 591 RDEPAESPSETPGP----RPAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETP 642 E + PGP AGPAG+ A+ G P AG G A PS Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ 421 Query: 643 GP-SPAGP--TRDEPAKAGEAAE 662 GP P GP EP G + Sbjct: 422 GPGGPPGPKGNSGEPGAPGSKGD 444 Score = 71.6 bits (174), Expect = 2e-12 Identities = 120/420 (28%), Positives = 153/420 (36%), Gaps = 96/420 (22%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373 G+PG P GP +G G GP+ S EP G S+GD G GE Sbjct: 407 GAPGFPGAR--------GPSGPQGPGG-PPGPKGNSGEPGAPG----SKGD-TGAKGEPG 452 Query: 374 PEPLS--PKESKKRKLELSRREQPPTE-PGP--QSASEVEKIALNLEGCALSQGSL-RTG 427 P + P + + +R E PT PGP + + +G A +G G Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG 512 Query: 428 TQEVGGQ--DPGEAVQPCRQPL-GARVADKVRKRRKVDEGAGDSAAV------------- 471 + G PGEA +P L GA+ D G Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572 Query: 472 ASGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPA 530 A G A + G +G P KAG E GV G GP G G P PAGPA Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAG--ERGVP-GPPGAVGPA-GKDGEAGAQGPPGPAGPA 628 Query: 531 GDEPAESPSETPG----PRPAGPAGD--EPAES--PSETPGPRPAGPAGDE--PAESPSE 580 G+ + P+ +PG P PAGP G+ +P E P + P P+G G+ P E + Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688 Query: 581 TPGPSPAGPTR------DEPAESPSETPG----------------------PRPAGPAGD 612 P P PAGP ++ A+ + PG P P G GD Sbjct: 689 GP-PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747 Query: 613 EPAESPSETPGPR----------PAGPAGDEPAESPSETPGPS-PAGPT--RDEPAKAGE 659 + +PG P GPAG A GPS PAGPT R P GE Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAG---APGDKGESGPSGPAGPTGARGAPGDRGE 804 Score = 71.6 bits (174), Expect = 2e-12 Identities = 115/428 (26%), Positives = 139/428 (32%), Gaps = 134/428 (31%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKG----GGRVDE-GPQPRSVEPQDAGPLERSQGDEAGG 368 G+PG S GP + G GRV GP + P GP + G G Sbjct: 857 GAPGAKGARGSA-----GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK--GP 909 Query: 369 HGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGT 428 GE P R E+ PP PGP EK + +G A + G+ G Sbjct: 910 RGETGPAG--------RPGEVG----PPGPPGPAG----EKGSPGADGPAGAPGT--PGP 951 Query: 429 QEVGGQD-----------------PGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAA 470 Q + GQ PG + +P +Q P GA +G+ Sbjct: 952 QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA---------------SGERGP 996 Query: 471 VASGGAQTLALAGSPAPSGHPKAGHSENGVEED-------TEGRTGPKEGTPGSPSETPG 523 G LAG P SG A +E D G TGP G PG+P Sbjct: 997 PGPMGPP--GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA-GPPGAPGAPGA 1053 Query: 524 PSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR------------------ 565 P P GPAG + ET PAGP G A P+ GPR Sbjct: 1054 PGPVGPAGK--SGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111 Query: 566 -------PAGPAGDEPAESPSETPGPS-PAGPTRDEPAES---------PSETPGPRPAG 608 P GP G + PS GP+ P GP A P PGPR G Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR--G 1169 Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG--------PTRDEPAKAGEA 660 GD AGP G P PGP AG P +++ G Sbjct: 1170 RTGD--------------AGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRY 1215 Query: 661 AELQDAEV 668 DA V Sbjct: 1216 YRADDANV 1223 Score = 69.7 bits (169), Expect = 8e-12 Identities = 112/400 (28%), Positives = 133/400 (33%), Gaps = 71/400 (17%) Query: 305 EGSRKVEEE----GSPGDPDHEASTQGR-------TCGPEHSKGGGRVDEGPQPRSVEPQ 353 EG R E G PG P R GP+ G R GP P Sbjct: 466 EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPK-GPAGERGSPGPAGPKGSPG 524 Query: 354 DAG-PLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIAL 412 +AG P E G G K R PP PG + + V Sbjct: 525 EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFP- 583 Query: 413 NLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 +G A G + G + V G P AV P + A E G+ Sbjct: 584 GPKGAAGEPG--KAGERGVPG--PPGAVGPAGKDGEAGAQGPPGPAGPAGE-RGEQGPAG 638 Query: 473 SGGAQTL-ALAGSPAPSGHPKAGHSENGVEEDTEGRTGP-----KEGTPGSPSETPGPSP 526 S G Q L AG P +G P E GV D G GP + G PG P P Sbjct: 639 SPGFQGLPGPAGPPGEAGKP----GEQGVPGDL-GAPGPSGARGERGFPGERGVQGPPGP 693 Query: 527 AGPAG------DEPAESPSETPG----------------------PRPAGPAGDEPAESP 558 AGP G ++ A+ + PG P P G GD + Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753 Query: 559 SETPGPR-------PAGPAGDEPAESPSETPGPS-PAGPTRDEPAESPSETPGPRPAGPA 610 +PG P GP G A GPS PAGPT A P + P P GPA Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA--PGDRGEPGPPGPA 811 Query: 611 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPS-PAGP 649 G A P P G GD A+ + PGP+ PAGP Sbjct: 812 GF--AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP 849 Score = 69.7 bits (169), Expect = 8e-12 Identities = 119/418 (28%), Positives = 139/418 (33%), Gaps = 103/418 (24%) Query: 314 GSPGDPDHEAST--------QGRTC--GPEHSKGGGRVDEGPQPRSV--EPQDAGPL--- 358 GSPG P + T GR GP ++G V P P+ EP AG Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601 Query: 359 -------ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPT-EPGPQSASEVEKI 410 + EAG G P P P R EQ P PG Q Sbjct: 602 GPPGAVGPAGKDGEAGAQGP--PGPAGPAGE--------RGEQGPAGSPGFQG------- 644 Query: 411 ALNLEGCALSQGSL-RTGTQEVGGQ--------------DPGE-AVQPCRQPLGARVADK 454 L G A G + G Q V G PGE VQ P G R A+ Sbjct: 645 ---LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANG 701 Query: 455 VRKRRKVDEGAGDSAAVASGGAQTL-ALAGSPAPSGH-----PKAGHSENGVEEDTEGRT 508 D GD+ A + G+Q L G P G PK + G + +G Sbjct: 702 APGN---DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG-PKGADGSP 757 Query: 509 GPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR-------------PAGPAGDEPA 555 G K+G G P PAG GD+ PS GP P GPAG Sbjct: 758 G-KDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP 816 Query: 556 ESPSETPG----PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPA--- 607 PG P AG GD P+ G P P G A+ + GP A Sbjct: 817 PGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGF 876 Query: 608 -GPAGDEPAESPSETPG-PRPAGPAGDE----------PAESPSETPGPSPAGPTRDE 653 G AG PS G P P GPAG E PA P E P P GP ++ Sbjct: 877 PGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEK 934 Score = 69.3 bits (168), Expect = 1e-11 Identities = 101/365 (27%), Positives = 126/365 (34%), Gaps = 48/365 (13%) Query: 331 GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELS 390 GP +G P P+ + P E G G P + + + K Sbjct: 182 GPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRP 241 Query: 391 RREQPPTEPGPQSASEVEKIALNLEGCALSQG--SLRTGTQEVGGQDP-GEAVQPCRQPL 447 PP GPQ A + A L G +G L + G P GE P Sbjct: 242 GERGPP---GPQGARGLPGTA-GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297 Query: 448 GARVADKVRKRRKVDEGAGDSAAV-----ASGGAQTLALAGSPAPSGHPKA-GHSENGVE 501 ++ + + GA A A+G A G P G P A G Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGP 357 Query: 502 EDTEGRTGPKEGTPGSPSETPGPS-PAGPAGDEPAESPSETPG----PRPAGPAGDEPAE 556 + G GP +G G P PGP+ AGPAG+ A+ G P AG G A Sbjct: 358 QGPRGSEGP-QGVRGEPGP-PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 557 SPSETPGP-RPAGPAGD--EPAESPSE-------TPGP----SPAGPTRDEPAESPSETP 602 PS GP P GP G+ EP S+ PGP P GP +E P Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 603 GPRP-AGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKA 657 GP GP G+ PG P GPAG E P PAGP + P +A Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG--------ERGSPGPAGP-KGSPGEA 526 Query: 658 GEAAE 662 G E Sbjct: 527 GRPGE 531 Score = 67.8 bits (164), Expect = 3e-11 Identities = 76/254 (29%), Positives = 92/254 (36%), Gaps = 54/254 (21%) Query: 463 EGAGDSAAV--ASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSP 518 +GA SA A+G G P PSG+ AG EG GP+ G G P Sbjct: 862 KGARGSAGPPGATGFPGAAGRVGPPGPSGN--AGPPGPPGPAGKEGGKGPRGETGPAGRP 919 Query: 519 SETPGPSPAGPAG-------DEPAESPSETPGPRPA----------------------GP 549 E P P GPAG D PA +P TPGP+ GP Sbjct: 920 GEVGPPGPPGPAGEKGSPGADGPAGAPG-TPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978 Query: 550 AGDEPAESPSETPG----PRPAGPAG--DEPAESPSETPGPSPAGPTRDEPAESPSETPG 603 +G+ + PS G P P GP G P ES E + P RD + + Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038 Query: 604 PRPAGPAGDEPAESPSETPGPR-------PAGPAGDEPAESPSETPGPS-PAGPTRDEPA 655 PAGP G A GP GPAG P GP+ P GP D+ Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK-- 1096 Query: 656 KAGEAAELQDAEVE 669 GE E D ++ Sbjct: 1097 --GETGEQGDRGIK 1108 Score = 66.2 bits (160), Expect = 9e-11 Identities = 70/230 (30%), Positives = 85/230 (36%), Gaps = 45/230 (19%) Query: 473 SGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGP 529 SG A G+P G P G + +G+ G K G G+ + P PAGP Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846 Query: 530 AGDEPAESPSETPGPRPA-------------GPAGDEPAESPSETPG-PRPAGPAGDE-- 573 AG PG + A G AG PS G P P GPAG E Sbjct: 847 AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906 Query: 574 --------PAESPSETPGPSPAGPTRDE---PAESPSETPG-PRPAGPAGDE-----PAE 616 PA P E P P GP ++ A+ P+ PG P P G AG P + Sbjct: 907 KGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQ 966 Query: 617 SPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAKAGEAAE 662 E P GP+G+ + PS G P P GP P AG E Sbjct: 967 R-GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP----PGLAGPPGE 1011 Score = 52.0 bits (123), Expect = 2e-06 Identities = 54/175 (30%), Positives = 64/175 (36%), Gaps = 36/175 (20%) Query: 515 PGSPSETPGPSPAGPAGDEP--------AESPSETPGPR----PAGPAGDEPAESPSETP 562 PG+ P P G E E P GPR PAGP G + P Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141 Query: 563 G-PRPAGPAG----------------DEPAESPSETPGPSPAGPTRDEPAESPSETPGPR 605 G P P GP G DE + PG P GP+ P PGP+ Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPG--PMGPSGPRGLPGPPGAPGPQ 199 Query: 606 P-AGPAGDEPAESPSETP-GPR-PAGPAGDEPAESPSETPG-PSPAGPTRDEPAK 656 GP G EP E + P GPR P GP G + + PG P GP + A+ Sbjct: 200 GFQGPPG-EPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253 Score = 45.4 bits (106), Expect = 2e-04 Identities = 42/150 (28%), Positives = 52/150 (34%), Gaps = 40/150 (26%) Query: 529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PSP 586 P + +ESP++ GP GD GPR P GPAG + PG P P Sbjct: 93 PVCPDGSESPTDQETTGVEGPKGDT---------GPRGPRGPAGPPGRDGIPGQPGLPGP 143 Query: 587 AGPTRDEPAESPSETPGPRPAGPAG-------------DEPAESPSETPGPRPAGPAGDE 633 GP P P GP G DE + PGP GP+G Sbjct: 144 PGP--------------PGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPM--GPSGPR 187 Query: 634 PAESPSETPGPSPAGPTRDEPAKAGEAAEL 663 P PGP EP + G + + Sbjct: 188 GLPGPPGAPGPQGFQGPPGEPGEPGASGPM 217 Score = 44.7 bits (104), Expect = 3e-04 Identities = 90/336 (26%), Positives = 106/336 (31%), Gaps = 88/336 (26%) Query: 287 GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--------G 338 GP + P P P E+GSPG D A G T GP+ G G Sbjct: 914 GPAGRPGEVGPPGPPGP------AGEKGSPG-ADGPAGAPG-TPGPQGIAGQRGVVGLPG 965 Query: 339 GRVDEG----PQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPKESKKRKLELSRRE 393 R + G P P S EP GP +G GE P P+ P E R Sbjct: 966 QRGERGFPGLPGP-SGEPGKQGP--------SGASGERGPPGPMGPPGLAGPPGESGREG 1016 Query: 394 QPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVAD 453 P E P +G ++G E G P A P A Sbjct: 1017 APGAEGSP-----------GRDGSPGAKGD----RGETGPAGPPGAPGAPGAPGPVGPAG 1061 Query: 454 KVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDT--------E 505 K R + AG + V GA+ G P G P+ E G + D Sbjct: 1062 KSGDRGETGP-AGPAGPVGPVGAR-----GPAGPQG-PRGDKGETGEQGDRGIKGHRGFS 1114 Query: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGD 552 G GP G PGSP E +GPAG + PG P P G GD Sbjct: 1115 GLQGPP-GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173 Query: 553 EPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 588 AGP G P PGP AG Sbjct: 1174 --------------AGPVGPPGPPGPPGPPGPPSAG 1195 Score = 32.7 bits (73), Expect = 1.1 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Query: 572 DEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPA 630 DE P P + +ESP++ GP GD GPR PAGP Sbjct: 76 DETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPR------GPRGPAGPP 129 Query: 631 GDEPAESPSETPG-PSPAGP 649 G + PG P P GP Sbjct: 130 GRDGIPGQPGLPGPPGPPGP 149 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 88.2 bits (217), Expect = 2e-17 Identities = 97/369 (26%), Positives = 130/369 (35%), Gaps = 44/369 (11%) Query: 319 PDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLS 378 P S G+ GP GG +GP P +PQ GP + G +P+ Sbjct: 47 PQGPPSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQ--GPPPQGGNKPQGPPPPGKPQGPP 102 Query: 379 PKESKKRKLELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDP 436 P+ K R S R P P P PQ ++ + G G + G GG P Sbjct: 103 PQGDKSR----SPRSPPGKPQGPPPQGGNQPQ-------GPPPPPGKPQ-GPPPQGGNKP 150 Query: 437 GEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHS 496 + P +P G + R GG Q G P P G P+ Sbjct: 151 -QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPP 206 Query: 497 ENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP-GPRPAG---PAGD 552 + G K P P + GP P G + A SP P GP P G P G Sbjct: 207 QGG----------NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP 256 Query: 553 EPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETP-GPRPAG--- 608 P P + GP P G + P + GP P G ++ + SP P GP P G Sbjct: 257 PPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314 Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668 P G P P + GP P G + P + GP P G ++ A++ + Sbjct: 315 PQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQ 372 Query: 669 ESSAKSGKP 677 E + G P Sbjct: 373 EGNNPQGPP 381 Score = 84.7 bits (208), Expect = 3e-16 Identities = 94/363 (25%), Positives = 126/363 (34%), Gaps = 54/363 (14%) Query: 303 PLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--------GGRVDEGPQPRSVEPQD 354 P +G K + PG P ++ P G GG +GP P +PQ Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ- 140 Query: 355 AGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKIAL 412 GP + G +P+ P+ K + S R P P P PQ ++ + Sbjct: 141 -GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR---SSRSPPGKPQGPPPQGGNQPQ---- 192 Query: 413 NLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 G G+ G Q +P G K + + SA Sbjct: 193 --------------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238 Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGD 532 G Q G P G P G + + G K P P + GP P G + Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPP----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 294 Query: 533 EPAESPSETP-GPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 588 + SP P GP P G P G P P + GP P G + P + GP P G Sbjct: 295 RSSRSPPGKPQGPPPQGGNQPQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352 Query: 589 PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 648 ++ A SP PG +P GP P + + GP P PAG P + P P P G Sbjct: 353 GSKSRSARSP---PG-KPQGP----PQQEGNNPQGPPP--PAGGNP-QQPQAPPAGQPQG 401 Query: 649 PTR 651 P R Sbjct: 402 PPR 404 Score = 71.2 bits (173), Expect = 3e-12 Identities = 66/236 (27%), Positives = 83/236 (35%), Gaps = 35/236 (14%) Query: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521 D +S ++ +G Q G P G P G P +G G+ + Sbjct: 22 DVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP---------PPQG--GNQPQG 70 Query: 522 PGPSPAGPAGDEP--------AESPSETPGPRPAGPAGDEPAESPSETPGPRPAG---PA 570 P P P P G P P + GP P G P P + GP P G P Sbjct: 71 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130 Query: 571 GDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETP-GPRPAG- 628 G P P + GP P G + + P + GP P G + SP P GP P G Sbjct: 131 G--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188 Query: 629 --PAGDEPAESPSETPGPSPAG---PTRDEPAKAGEAAELQDAEVESSAKS--GKP 677 P G P P + GP P G P P + Q SA+S GKP Sbjct: 189 NQPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 84.7 bits (208), Expect = 3e-16 Identities = 61/185 (32%), Positives = 84/185 (45%), Gaps = 11/185 (5%) Query: 484 SPAPSGHPKAGHSENGVE-EDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-AESP 538 +P P G P+ + G + + R G EG P G+ S+ P P P P G P + Sbjct: 50 TPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQ 109 Query: 539 SETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP-A 595 S+ P PRP P G P + S+ P PRP P G P + S+ P P P P P Sbjct: 110 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 169 Query: 596 ESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEPAESPSETPGPSP-AGPTRDE 653 + S+ P P P P G P + S+ P PRP P G P + +++ GP P G Sbjct: 170 GNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGNQSQGPPPRPGKPEGP 228 Query: 654 PAKAG 658 P++ G Sbjct: 229 PSQGG 233 Score = 81.6 bits (200), Expect = 2e-15 Identities = 60/177 (33%), Positives = 78/177 (44%), Gaps = 10/177 (5%) Query: 488 SGHPKAGHSENGVE-EDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-AESPSETP 542 SG P+ + G + + T G EG P G+ S+ P P P P G P + S+ P Sbjct: 33 SGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 92 Query: 543 GPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP-AESPS 599 PRP P G P + S+ P PRP P G P + S+ P P P P P + S Sbjct: 93 PPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 152 Query: 600 ETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP 654 + P PRP P G P + S+ P P P P G P + S+ P P P P P Sbjct: 153 QGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 209 Score = 81.3 bits (199), Expect = 3e-15 Identities = 72/252 (28%), Positives = 95/252 (37%), Gaps = 22/252 (8%) Query: 427 GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPA 486 G + GG P P +P G + + GG Q+ P Sbjct: 38 GRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG 97 Query: 487 -PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-AESPSET 541 P G P G +++ + R G EG P G+ S+ P P P P G P + S+ Sbjct: 98 KPEGQPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG 154 Query: 542 PGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP-AESP 598 P PRP P G P + S+ P P P P G P + S+ P P P P P + Sbjct: 155 PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214 Query: 599 SETPGPRPAGPAG-DEPAESPSETPGPRPAGPAGDEPAES--------PSETPGPSPAG- 648 S+ P PRP P G + + P P P P G P E P GP P G Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGG 274 Query: 649 -PTRDEPAKAGE 659 P + P AG+ Sbjct: 275 NPQQPLPPPAGK 286 Score = 79.0 bits (193), Expect = 1e-14 Identities = 59/190 (31%), Positives = 80/190 (42%), Gaps = 13/190 (6%) Query: 474 GGAQTLALAGSPA-PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGP 529 GG Q+ P P G P G +++ + R G EG P G+ S+ P P P P Sbjct: 106 GGNQSQGPPPRPGKPEGPPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 162 Query: 530 AGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEPAESPSETPGPSP- 586 G P + S+ P P P P G P + S+ P PRP P G P + +++ GP P Sbjct: 163 EGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGNQSQGPPPR 221 Query: 587 AGPTRDEPAE--SPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 644 G P++ + + P P P P G P E P P P G P + P P Sbjct: 222 PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLP 281 Query: 645 SPAGPTRDEP 654 PAG + P Sbjct: 282 PPAGKPQGPP 291 Score = 76.6 bits (187), Expect = 7e-14 Identities = 61/182 (33%), Positives = 80/182 (43%), Gaps = 10/182 (5%) Query: 479 LALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEP-AES 537 LAL+ + + + S + + EGR P+ G P TP P P P G P + Sbjct: 11 LALSSAQSLNEDVSQEESPSVISGKPEGRR-PQGGN--QPQRTP-PPPGKPEGRPPQGGN 66 Query: 538 PSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP- 594 S+ P PRP P G P + S+ P PRP P G P + S+ P P P P P Sbjct: 67 QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQ 126 Query: 595 AESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRD 652 + S+ P PRP P G P + S+ P PRP P G P + S+ P P P P Sbjct: 127 GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGP 186 Query: 653 EP 654 P Sbjct: 187 PP 188 Score = 75.1 bits (183), Expect = 2e-13 Identities = 76/297 (25%), Positives = 106/297 (35%), Gaps = 40/297 (13%) Query: 371 EDRPEPLSPKESKKRKLELSRREQPPTEPG------PQSASEVEKIALNLEGCALSQGSL 424 E+ P +S K +R ++ ++ P PG PQ ++ + G G Sbjct: 26 EESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQ-------GPPPRPGKP 78 Query: 425 RTGTQEVGGQDPGEAVQPCRQ----PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA 480 + G Q G +P + P G + R EG GG Q+ Sbjct: 79 EGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQ-----GGNQSQG 133 Query: 481 LAGSPA-PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-A 535 P P G P G +++ + R G EG P G+ S+ P P P P G P Sbjct: 134 PPPRPGKPEGPPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQG 190 Query: 536 ESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDE---------PAESPSETPGPS 585 + S+ P PRP P G P + S+ P PRP P G P P + GP Sbjct: 191 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPP 250 Query: 586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 642 P + + P GP P G +P P+ P P P G P P P Sbjct: 251 PQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307 Score = 66.6 bits (161), Expect = 7e-11 Identities = 80/333 (24%), Positives = 109/333 (32%), Gaps = 49/333 (14%) Query: 289 QDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPR 348 +D + PS + EG R P +GR P+ GG +GP PR Sbjct: 21 EDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRP--PQ----GGNQSQGPPPR 74 Query: 349 SVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVE 408 +P+ P GG+ P P K + ++ + PP PG Sbjct: 75 PGKPEGPPP--------QGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP------ 120 Query: 409 KIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDS 468 +G G + G P P G + R EG Sbjct: 121 ------------EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 168 Query: 469 AAVASGGAQTLALAGSPA-PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGP 524 GG Q+ P P G P G +++ + R G EG P G+ S+ P P Sbjct: 169 -----GGNQSQGPPPHPGKPEGPPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPP 220 Query: 525 SPAGPAG-DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 583 P P G + + P P P P G P E P P P G P + P Sbjct: 221 RPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPL 280 Query: 584 PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAE 616 P PAG +P P G RP P +P + Sbjct: 281 PPPAG----KPQGPPPPPQGGRPHRPPQGQPPQ 309 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 5/110 (4%) Query: 557 SPSETPGPRPAGPAGDEP--AESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEP 614 S E+P P G P P TP P R + S+ P PRP P G P Sbjct: 24 SQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPP 83 Query: 615 -AESPSETPGPRPAGPAGDEPAESPSETPGPSP-AGPTRDEPAKAGEAAE 662 + S+ P PRP P G +P + +++ GP P G P + G ++ Sbjct: 84 QGGNQSQGPPPRPGKPEG-QPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 132 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 82.4 bits (202), Expect = 1e-15 Identities = 114/436 (26%), Positives = 151/436 (34%), Gaps = 65/436 (14%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDH--EASTQGRTCGPEHSKG-----GGRVDEGPQPRS 349 P+ P P ++G PG P E QG+T GP G G + GP Sbjct: 798 PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT-GPPGPPGVVGPQGAAGETGPMGER 856 Query: 350 VEPQDAGP-----------LERSQGDEA--GGHGEDRPEPLSPKESKKRKLE------LS 390 P GP E ++GD G G+D P L ++ L Sbjct: 857 GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 916 Query: 391 RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450 E P PGP + S E+ A G G R G Q G + V + P+G Sbjct: 917 GNEGPSGPPGP-AGSPGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPT 973 Query: 451 VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510 D V+ + AG G + G P G K E+G G GP Sbjct: 974 GRDGVQGPVGLPGPAGPPGVAGEDGDK--GEVGDPGQKG-TKGNKGEHG-PPGPPGPIGP 1029 Query: 511 KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAES 557 G PG+ P GP G A+ T G P P+G G+ Sbjct: 1030 V-GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1088 Query: 558 PSETPGPR-PAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPG----PRPAGPAG 611 P PGP P GPAG A+ P PG GP ++ S +PG P GP G Sbjct: 1089 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148 Query: 612 DEPAESPSETPG----PRPAGPAGDE-------PAESPSETPGPSPAGPTRDEPAKAGEA 660 + + S PG P P GP GD+ P P + P GP + AK Sbjct: 1149 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1208 Query: 661 AELQDAEVESSAKSGK 676 + + + S +G+ Sbjct: 1209 EDGEPGQPGSPGPTGE 1224 Score = 82.4 bits (202), Expect = 1e-15 Identities = 119/427 (27%), Positives = 146/427 (34%), Gaps = 79/427 (18%) Query: 312 EEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLERSQGDE 365 E G PG P QG T G E +KG D GP + AG P ER Sbjct: 855 ERGHPGPPGPPGE-QGLPGTAGKEGTKG----DPGPPGAPGKDGPAGLRGFPGERGLPGT 909 Query: 366 AGGHG----EDRPEPLSPKESKKRKLELSRREQ--PPTEPGPQ----SASEV----EKIA 411 AGG G E P P S + PP PGPQ +A E EK Sbjct: 910 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 969 Query: 412 LNLEGCALSQGSLR----TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGA 465 + G QG + G V G+D GE P K K K + G Sbjct: 970 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---------GQKGTKGNKGEHGP 1020 Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPG---- 516 Q A P GH +E T G GP +G PG Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080 Query: 517 -------SPSETPGP-SPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG---- 563 P PGP P GPAG A+ P PG GP G++ S +PG Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140 Query: 564 PRPAGPAGDEPAESPSETPG----PSPAGPTRDE-------PAESPSETPGPRPAGPAGD 612 P GP G+ + S PG P P GPT D+ P P + P GP G Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200 Query: 613 EPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668 + A+ G P GP G+ P G PAG E + G+ A+ + Sbjct: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG--PAGSPGSEGRQGGKGAKGDPGAI 1258 Query: 669 ESSAKSG 675 + K+G Sbjct: 1259 GAPGKTG 1265 Score = 69.3 bits (168), Expect = 1e-11 Identities = 95/324 (29%), Positives = 117/324 (36%), Gaps = 55/324 (16%) Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSA-SEVEKIAL-NLEG 416 +R + G GED PE PK R P +PGP E K+ + L G Sbjct: 669 DRGEVGVPGSRGEDGPE--GPKG----------RTGPTGDPGPPGLMGEKGKLGVPGLPG 716 Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 QG + G G+ + P G R R +R G A Sbjct: 717 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR------GPRGATG 770 Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVE--EDTEGRTGPKEGTPGSPSETPGPSPAGPA 530 GA+ +G P G P E G+ + G GPK G PG P + P G Sbjct: 771 KSGAK--GTSGGDGPHGPP----GERGLPGPQGPNGFPGPK-GPPGPPGKDGLPGHPGQR 823 Query: 531 GDEPAESPSETPGPRPA-GPAGDEPAESPSETPG-PRPAGPAGDEPA------ESPSETP 582 G+ + + PGP GP G P G P P GP G++ E P Sbjct: 824 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 883 Query: 583 GPSPAGPTRDEPAES---PSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPA 635 GP P P +D PA P E P AG G + E PS PGP + G AG Sbjct: 884 GP-PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 942 Query: 636 ESPSETPGPSPAGPTRDEPAKAGE 659 P PGP GP P AGE Sbjct: 943 IGPPGRPGPQ--GP----PGAAGE 960 Score = 62.8 bits (151), Expect = 1e-09 Identities = 93/363 (25%), Positives = 119/363 (32%), Gaps = 75/363 (20%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-ERSQGDEAGGHG-E 371 G PG P GP G D GPQ + GP E+ + E+G G + Sbjct: 1091 GPPGPP-----------GPRGPAGPNGAD-GPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1138 Query: 372 DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEV 431 P P+ + K E + P EPGP +G G Sbjct: 1139 GEPGVKGPRGERGEKGESGQ----PGEPGPPGP----------KGPTGDDGPKGNPGPVG 1184 Query: 432 GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491 DPG + G R D + R D G + G G P P G Sbjct: 1185 FPGDPGPPGEG-----GPRGQDGAKGDRGEDGEPGQPGSPGPTGEN-----GPPGPLG-- 1232 Query: 492 KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPG------ 543 K G + + E +G G K G G+P +T PAGPAG + PG Sbjct: 1233 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1292 Query: 544 -PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTRDEPA 595 P G AG P PG R GD A+ PG P G D Sbjct: 1293 RPGATGQAGPPGPVGPPGLPGLR-----GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL 1347 Query: 596 ESPSETPGPR----------PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSET 641 P +PG + P GP G P+ G + P GP G++ + P Sbjct: 1348 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1407 Query: 642 PGP 644 PGP Sbjct: 1408 PGP 1410 Score = 55.8 bits (133), Expect = 1e-07 Identities = 97/391 (24%), Positives = 131/391 (33%), Gaps = 73/391 (18%) Query: 306 GSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ---PRSVEPQDAGPLERSQ 362 G+R ++EE GD A G E + EG Q P++ +P A + Q Sbjct: 192 GARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQ 251 Query: 363 GDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEP---------GPQSASEVEKIALN 413 P+ P ++ ++ L PP E G + V + + Sbjct: 252 PSRLHRPQNQEPQSQDPTPGEEEEI-LESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML 310 Query: 414 LEGCALSQGSLRT-GTQEVGGQ-----DPGEAVQPCRQPLGAR------VADKVRKRRKV 461 +EG +G G + G DPGE P R L + + Sbjct: 311 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370 Query: 462 DEGAGDSA-AVASGGAQT--------LALAGSPAPSGHPKAGHSENGVEEDTEGRTGP-- 510 G GD VA+ AQ LAL G P P G+ GR GP Sbjct: 371 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT--------------GRPGPLG 416 Query: 511 KEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG------- 563 + G+PG E+ P GP G + P G R G AG + A PG Sbjct: 417 QPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR--GRAGADGARGMPGDPGVKGDRGF 474 Query: 564 ------PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAES 617 P G GD A+ PG G D+ P PG +GP G + Sbjct: 475 DGLPGLPGEKGHRGDTGAQGLPGPPGED--GERGDDGEIGPRGLPG--ESGPRGLLGPKG 530 Query: 618 PSETPGPRPA----GPAGDEPAESPSETPGP 644 P PGP GP G + + P PGP Sbjct: 531 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 561 Score = 50.4 bits (119), Expect = 5e-06 Identities = 53/184 (28%), Positives = 65/184 (35%), Gaps = 16/184 (8%) Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSE--TPG----PSP 526 SG L G P G P + + +G GP +G PG P + TPG P P Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGP-QGEPGPPGQQGTPGTQGLPGP 576 Query: 527 AGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSET 581 G G + P PG P GP G E P T G + P+GP G P Sbjct: 577 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636 Query: 582 PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSE 640 G + E E P G G + PG R GP G + P+ Sbjct: 637 KGVDGIRGLKGHKGEK-GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 695 Query: 641 TPGP 644 PGP Sbjct: 696 DPGP 699 Score = 43.1 bits (100), Expect = 8e-04 Identities = 110/436 (25%), Positives = 128/436 (29%), Gaps = 133/436 (30%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373 G PGDP + + G R D G Q P + G E G GE Sbjct: 461 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG--------ERGDDGEIG 512 Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433 P L P ES R L + PP PGP ++G +GSL G Q G Sbjct: 513 PRGL-PGESGPRGL--LGPKGPPGIPGPPGVR-------GMDGPQGPKGSL--GPQGEPG 560 Query: 434 QDPGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTL-ALAGSPAPSGHP 491 PG+ P Q L +GA G G L + GS P GHP Sbjct: 561 P-PGQQGTPGTQGLPG------------PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607 Query: 492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA---- 547 KEG PG+ P GP G PGPR Sbjct: 608 G------------------KEGPPGTKGNQGPSGPQGPLG---------YPGPRGVKGVD 640 Query: 548 ---------------------GPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPS 585 G G + PG R GP G + P+ PGP Sbjct: 641 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700 Query: 586 --------------PAGPTRDEPAES--------PSETPGPR----PAGPAGDEPAESPS 619 P P R P S S G R +GP G+ P Sbjct: 701 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 760 Query: 620 ETPGPR----------------PAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662 GPR P GP G+ P G P P GP P K G Sbjct: 761 GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP-GPPGKDGLPGH 819 Query: 663 L-QDAEVESSAKSGKP 677 Q EV K+G P Sbjct: 820 PGQRGEVGFQGKTGPP 835 Score = 38.1 bits (87), Expect = 0.027 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 3/119 (2%) Query: 540 ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPS 599 E P + A P + PS P+ P +P E S P +E A P Sbjct: 234 ERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPR 293 Query: 600 ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658 G + PA EP PGP GPAG PGP R P +AG Sbjct: 294 GLKGEK-GEPAVLEPGMLVEGPPGPE--GPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 349 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 82.4 bits (202), Expect = 1e-15 Identities = 114/436 (26%), Positives = 151/436 (34%), Gaps = 65/436 (14%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDH--EASTQGRTCGPEHSKG-----GGRVDEGPQPRS 349 P+ P P ++G PG P E QG+T GP G G + GP Sbjct: 777 PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT-GPPGPPGVVGPQGAAGETGPMGER 835 Query: 350 VEPQDAGP-----------LERSQGDEA--GGHGEDRPEPLSPKESKKRKLE------LS 390 P GP E ++GD G G+D P L ++ L Sbjct: 836 GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 895 Query: 391 RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450 E P PGP + S E+ A G G R G Q G + V + P+G Sbjct: 896 GNEGPSGPPGP-AGSPGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPT 952 Query: 451 VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510 D V+ + AG G + G P G K E+G G GP Sbjct: 953 GRDGVQGPVGLPGPAGPPGVAGEDGDK--GEVGDPGQKG-TKGNKGEHG-PPGPPGPIGP 1008 Query: 511 KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAES 557 G PG+ P GP G A+ T G P P+G G+ Sbjct: 1009 V-GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1067 Query: 558 PSETPGPR-PAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPG----PRPAGPAG 611 P PGP P GPAG A+ P PG GP ++ S +PG P GP G Sbjct: 1068 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1127 Query: 612 DEPAESPSETPG----PRPAGPAGDE-------PAESPSETPGPSPAGPTRDEPAKAGEA 660 + + S PG P P GP GD+ P P + P GP + AK Sbjct: 1128 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1187 Query: 661 AELQDAEVESSAKSGK 676 + + + S +G+ Sbjct: 1188 EDGEPGQPGSPGPTGE 1203 Score = 82.4 bits (202), Expect = 1e-15 Identities = 119/427 (27%), Positives = 146/427 (34%), Gaps = 79/427 (18%) Query: 312 EEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLERSQGDE 365 E G PG P QG T G E +KG D GP + AG P ER Sbjct: 834 ERGHPGPPGPPGE-QGLPGTAGKEGTKG----DPGPPGAPGKDGPAGLRGFPGERGLPGT 888 Query: 366 AGGHG----EDRPEPLSPKESKKRKLELSRREQ--PPTEPGPQ----SASEV----EKIA 411 AGG G E P P S + PP PGPQ +A E EK Sbjct: 889 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 948 Query: 412 LNLEGCALSQGSLR----TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGA 465 + G QG + G V G+D GE P K K K + G Sbjct: 949 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---------GQKGTKGNKGEHGP 999 Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPG---- 516 Q A P GH +E T G GP +G PG Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059 Query: 517 -------SPSETPGP-SPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG---- 563 P PGP P GPAG A+ P PG GP G++ S +PG Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119 Query: 564 PRPAGPAGDEPAESPSETPG----PSPAGPTRDE-------PAESPSETPGPRPAGPAGD 612 P GP G+ + S PG P P GPT D+ P P + P GP G Sbjct: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1179 Query: 613 EPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668 + A+ G P GP G+ P G PAG E + G+ A+ + Sbjct: 1180 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG--PAGSPGSEGRQGGKGAKGDPGAI 1237 Query: 669 ESSAKSG 675 + K+G Sbjct: 1238 GAPGKTG 1244 Score = 69.3 bits (168), Expect = 1e-11 Identities = 95/324 (29%), Positives = 117/324 (36%), Gaps = 55/324 (16%) Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSA-SEVEKIAL-NLEG 416 +R + G GED PE PK R P +PGP E K+ + L G Sbjct: 648 DRGEVGVPGSRGEDGPE--GPKG----------RTGPTGDPGPPGLMGEKGKLGVPGLPG 695 Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 QG + G G+ + P G R R +R G A Sbjct: 696 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR------GPRGATG 749 Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVE--EDTEGRTGPKEGTPGSPSETPGPSPAGPA 530 GA+ +G P G P E G+ + G GPK G PG P + P G Sbjct: 750 KSGAK--GTSGGDGPHGPP----GERGLPGPQGPNGFPGPK-GPPGPPGKDGLPGHPGQR 802 Query: 531 GDEPAESPSETPGPRPA-GPAGDEPAESPSETPG-PRPAGPAGDEPA------ESPSETP 582 G+ + + PGP GP G P G P P GP G++ E P Sbjct: 803 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862 Query: 583 GPSPAGPTRDEPAES---PSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPA 635 GP P P +D PA P E P AG G + E PS PGP + G AG Sbjct: 863 GP-PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 921 Query: 636 ESPSETPGPSPAGPTRDEPAKAGE 659 P PGP GP P AGE Sbjct: 922 IGPPGRPGPQ--GP----PGAAGE 939 Score = 62.8 bits (151), Expect = 1e-09 Identities = 93/363 (25%), Positives = 119/363 (32%), Gaps = 75/363 (20%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-ERSQGDEAGGHG-E 371 G PG P GP G D GPQ + GP E+ + E+G G + Sbjct: 1070 GPPGPP-----------GPRGPAGPNGAD-GPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1117 Query: 372 DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEV 431 P P+ + K E + P EPGP +G G Sbjct: 1118 GEPGVKGPRGERGEKGESGQ----PGEPGPPGP----------KGPTGDDGPKGNPGPVG 1163 Query: 432 GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491 DPG + G R D + R D G + G G P P G Sbjct: 1164 FPGDPGPPGEG-----GPRGQDGAKGDRGEDGEPGQPGSPGPTGEN-----GPPGPLG-- 1211 Query: 492 KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPG------ 543 K G + + E +G G K G G+P +T PAGPAG + PG Sbjct: 1212 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1271 Query: 544 -PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTRDEPA 595 P G AG P PG R GD A+ PG P G D Sbjct: 1272 RPGATGQAGPPGPVGPPGLPGLR-----GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL 1326 Query: 596 ESPSETPGPR----------PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSET 641 P +PG + P GP G P+ G + P GP G++ + P Sbjct: 1327 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1386 Query: 642 PGP 644 PGP Sbjct: 1387 PGP 1389 Score = 60.5 bits (145), Expect = 5e-09 Identities = 96/384 (25%), Positives = 128/384 (33%), Gaps = 80/384 (20%) Query: 306 GSRKVEEEGSPGDPDHEASTQG-----RTCGPEHSKGGGRVDEGPQPRSVEPQDAGP--- 357 G+R ++EE GD A G +C + + G E PQ + P Sbjct: 192 GARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQ 251 Query: 358 ---LERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNL 414 L R Q E P L ++ + LE + P PGP+ + + Sbjct: 252 PSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGP--PGPEGPAGL------- 302 Query: 415 EGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR------VADKVRKRRKVDEGAGDS 468 + ++ VG DPGE P R L + + G GD Sbjct: 303 ----IGPPGIQGNPGPVG--DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDK 356 Query: 469 A-AVASGGAQT--------LALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGS 517 VA+ AQ LAL G P P G+ GR GP + G+PG Sbjct: 357 GPVVAAQEAQAQAILQQARLALRGPPGPMGYT--------------GRPGPLGQPGSPGL 402 Query: 518 PSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------------P 564 E+ P GP G + P G R G AG + A PG P Sbjct: 403 KGESGDLGPQGPRGPQGLTGPPGKAGRR--GRAGADGARGMPGDPGVKGDRGFDGLPGLP 460 Query: 565 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 624 G GD A+ PG G D+ P PG +GP G + P PGP Sbjct: 461 GEKGHRGDTGAQGLPGPPGED--GERGDDGEIGPRGLPG--ESGPRGLLGPKGPPGIPGP 516 Query: 625 RPA----GPAGDEPAESPSETPGP 644 GP G + + P PGP Sbjct: 517 PGVRGMDGPQGPKGSLGPQGEPGP 540 Score = 50.4 bits (119), Expect = 5e-06 Identities = 53/184 (28%), Positives = 65/184 (35%), Gaps = 16/184 (8%) Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSE--TPG----PSP 526 SG L G P G P + + +G GP +G PG P + TPG P P Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGP-QGEPGPPGQQGTPGTQGLPGP 555 Query: 527 AGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSET 581 G G + P PG P GP G E P T G + P+GP G P Sbjct: 556 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 615 Query: 582 PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSE 640 G + E E P G G + PG R GP G + P+ Sbjct: 616 KGVDGIRGLKGHKGEK-GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 674 Query: 641 TPGP 644 PGP Sbjct: 675 DPGP 678 Score = 43.1 bits (100), Expect = 8e-04 Identities = 110/436 (25%), Positives = 128/436 (29%), Gaps = 133/436 (30%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373 G PGDP + + G R D G Q P + G E G GE Sbjct: 440 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG--------ERGDDGEIG 491 Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433 P L P ES R L + PP PGP ++G +GSL G Q G Sbjct: 492 PRGL-PGESGPRGL--LGPKGPPGIPGPPGVR-------GMDGPQGPKGSL--GPQGEPG 539 Query: 434 QDPGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTL-ALAGSPAPSGHP 491 PG+ P Q L +GA G G L + GS P GHP Sbjct: 540 P-PGQQGTPGTQGLPG------------PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 586 Query: 492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA---- 547 KEG PG+ P GP G PGPR Sbjct: 587 G------------------KEGPPGTKGNQGPSGPQGPLG---------YPGPRGVKGVD 619 Query: 548 ---------------------GPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPS 585 G G + PG R GP G + P+ PGP Sbjct: 620 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 679 Query: 586 --------------PAGPTRDEPAES--------PSETPGPR----PAGPAGDEPAESPS 619 P P R P S S G R +GP G+ P Sbjct: 680 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 739 Query: 620 ETPGPR----------------PAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662 GPR P GP G+ P G P P GP P K G Sbjct: 740 GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP-GPPGKDGLPGH 798 Query: 663 L-QDAEVESSAKSGKP 677 Q EV K+G P Sbjct: 799 PGQRGEVGFQGKTGPP 814 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 82.4 bits (202), Expect = 1e-15 Identities = 114/436 (26%), Positives = 151/436 (34%), Gaps = 65/436 (14%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDH--EASTQGRTCGPEHSKG-----GGRVDEGPQPRS 349 P+ P P ++G PG P E QG+T GP G G + GP Sbjct: 884 PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT-GPPGPPGVVGPQGAAGETGPMGER 942 Query: 350 VEPQDAGP-----------LERSQGDEA--GGHGEDRPEPLSPKESKKRKLE------LS 390 P GP E ++GD G G+D P L ++ L Sbjct: 943 GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002 Query: 391 RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450 E P PGP + S E+ A G G R G Q G + V + P+G Sbjct: 1003 GNEGPSGPPGP-AGSPGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPT 1059 Query: 451 VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510 D V+ + AG G + G P G K E+G G GP Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDK--GEVGDPGQKG-TKGNKGEHG-PPGPPGPIGP 1115 Query: 511 KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAES 557 G PG+ P GP G A+ T G P P+G G+ Sbjct: 1116 V-GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1174 Query: 558 PSETPGPR-PAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPG----PRPAGPAG 611 P PGP P GPAG A+ P PG GP ++ S +PG P GP G Sbjct: 1175 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1234 Query: 612 DEPAESPSETPG----PRPAGPAGDE-------PAESPSETPGPSPAGPTRDEPAKAGEA 660 + + S PG P P GP GD+ P P + P GP + AK Sbjct: 1235 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1294 Query: 661 AELQDAEVESSAKSGK 676 + + + S +G+ Sbjct: 1295 EDGEPGQPGSPGPTGE 1310 Score = 82.4 bits (202), Expect = 1e-15 Identities = 119/427 (27%), Positives = 146/427 (34%), Gaps = 79/427 (18%) Query: 312 EEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLERSQGDE 365 E G PG P QG T G E +KG D GP + AG P ER Sbjct: 941 ERGHPGPPGPPGE-QGLPGTAGKEGTKG----DPGPPGAPGKDGPAGLRGFPGERGLPGT 995 Query: 366 AGGHG----EDRPEPLSPKESKKRKLELSRREQ--PPTEPGPQ----SASEV----EKIA 411 AGG G E P P S + PP PGPQ +A E EK Sbjct: 996 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 1055 Query: 412 LNLEGCALSQGSLR----TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGA 465 + G QG + G V G+D GE P K K K + G Sbjct: 1056 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---------GQKGTKGNKGEHGP 1106 Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPG---- 516 Q A P GH +E T G GP +G PG Sbjct: 1107 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1166 Query: 517 -------SPSETPGP-SPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG---- 563 P PGP P GPAG A+ P PG GP G++ S +PG Sbjct: 1167 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1226 Query: 564 PRPAGPAGDEPAESPSETPG----PSPAGPTRDE-------PAESPSETPGPRPAGPAGD 612 P GP G+ + S PG P P GPT D+ P P + P GP G Sbjct: 1227 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1286 Query: 613 EPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668 + A+ G P GP G+ P G PAG E + G+ A+ + Sbjct: 1287 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG--PAGSPGSEGRQGGKGAKGDPGAI 1344 Query: 669 ESSAKSG 675 + K+G Sbjct: 1345 GAPGKTG 1351 Score = 69.3 bits (168), Expect = 1e-11 Identities = 95/324 (29%), Positives = 117/324 (36%), Gaps = 55/324 (16%) Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSA-SEVEKIAL-NLEG 416 +R + G GED PE PK R P +PGP E K+ + L G Sbjct: 755 DRGEVGVPGSRGEDGPE--GPKG----------RTGPTGDPGPPGLMGEKGKLGVPGLPG 802 Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 QG + G G+ + P G R R +R G A Sbjct: 803 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR------GPRGATG 856 Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVE--EDTEGRTGPKEGTPGSPSETPGPSPAGPA 530 GA+ +G P G P E G+ + G GPK G PG P + P G Sbjct: 857 KSGAK--GTSGGDGPHGPP----GERGLPGPQGPNGFPGPK-GPPGPPGKDGLPGHPGQR 909 Query: 531 GDEPAESPSETPGPRPA-GPAGDEPAESPSETPG-PRPAGPAGDEPA------ESPSETP 582 G+ + + PGP GP G P G P P GP G++ E P Sbjct: 910 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 969 Query: 583 GPSPAGPTRDEPAES---PSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPA 635 GP P P +D PA P E P AG G + E PS PGP + G AG Sbjct: 970 GP-PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 1028 Query: 636 ESPSETPGPSPAGPTRDEPAKAGE 659 P PGP GP P AGE Sbjct: 1029 IGPPGRPGPQ--GP----PGAAGE 1046 Score = 62.8 bits (151), Expect = 1e-09 Identities = 93/363 (25%), Positives = 119/363 (32%), Gaps = 75/363 (20%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-ERSQGDEAGGHG-E 371 G PG P GP G D GPQ + GP E+ + E+G G + Sbjct: 1177 GPPGPP-----------GPRGPAGPNGAD-GPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1224 Query: 372 DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEV 431 P P+ + K E + P EPGP +G G Sbjct: 1225 GEPGVKGPRGERGEKGESGQ----PGEPGPPGP----------KGPTGDDGPKGNPGPVG 1270 Query: 432 GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491 DPG + G R D + R D G + G G P P G Sbjct: 1271 FPGDPGPPGEG-----GPRGQDGAKGDRGEDGEPGQPGSPGPTGEN-----GPPGPLG-- 1318 Query: 492 KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPG------ 543 K G + + E +G G K G G+P +T PAGPAG + PG Sbjct: 1319 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1378 Query: 544 -PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTRDEPA 595 P G AG P PG R GD A+ PG P G D Sbjct: 1379 RPGATGQAGPPGPVGPPGLPGLR-----GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL 1433 Query: 596 ESPSETPGPR----------PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSET 641 P +PG + P GP G P+ G + P GP G++ + P Sbjct: 1434 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1493 Query: 642 PGP 644 PGP Sbjct: 1494 PGP 1496 Score = 57.4 bits (137), Expect = 4e-08 Identities = 108/407 (26%), Positives = 138/407 (33%), Gaps = 70/407 (17%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGP-QPRSVEPQDAGP--LERSQGDEA---- 366 G PG+ H T + + G R D+G PR + P ++GP L +G Sbjct: 565 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL-PGESGPRGLLGPKGPPGIPGP 623 Query: 367 -GGHGEDRPEPLSPKESKKRKLELSRREQPPTE-----PGPQSA-----SEVEKIALNLE 415 G G D P+ PK S + E Q T PGPQ A + + L Sbjct: 624 PGVRGMDGPQ--GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP 681 Query: 416 GCALSQGSLRTGTQE-----VGGQDPGEAVQPCRQ--PLGARVADKVR--KRRKVDEGAG 466 G S G +E G Q P P P G + D +R K K ++G Sbjct: 682 GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED 741 Query: 467 DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--------------KE 512 G + + G G P E+G E +GRTGP K Sbjct: 742 G----FPGFKGDIGVKGDRGEVGVP-GSRGEDG-PEGPKGRTGPTGDPGPPGLMGEKGKL 795 Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPGPRPA- 567 G PG P P G G S G R +GP G+ P GPR A Sbjct: 796 GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 855 Query: 568 -------GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG----PRPAGPAGDEPAE 616 GD P P E P P GP + P PG P G G+ + Sbjct: 856 GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 915 Query: 617 SPSETPG-PRPAGPAGDEPAESP-SETPGPSPAGPTRDE--PAKAGE 659 + PG P GP G P E P P GP ++ P AG+ Sbjct: 916 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 962 Score = 57.0 bits (136), Expect = 6e-08 Identities = 92/363 (25%), Positives = 124/363 (34%), Gaps = 81/363 (22%) Query: 325 TQGRTCGPEHSKGGGRVDEGPQPRSV-------EPQDAGPLERSQGDEAGG--HGEDRPE 375 T R E+ +GG EGP + E + GP ++ +G HG P Sbjct: 323 TADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHG---PR 379 Query: 376 PLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQD 435 L ++ + LE + P PGP+ + + + ++ VG D Sbjct: 380 GLKGEKGEPAVLEPGMLVEGP--PGPEGPAGL-----------IGPPGIQGNPGPVG--D 424 Query: 436 PGEAVQPCRQPLGAR------VADKVRKRRKVDEGAGDSA-AVASGGAQT--------LA 480 PGE P R L + + G GD VA+ AQ LA Sbjct: 425 PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 484 Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSETPGPSPAGPAGDEPAESP 538 L G P P G+ GR GP + G+PG E+ P GP G + P Sbjct: 485 LRGPPGPMGYT--------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 530 Query: 539 SETPGPRPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAESPSETPGPS 585 G R G AG + A PG P G GD A+ PG Sbjct: 531 PGKAGRR--GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 588 Query: 586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPAESPSET 641 G D+ P PG +GP G + P PGP GP G + + P Sbjct: 589 --GERGDDGEIGPRGLPG--ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 644 Query: 642 PGP 644 PGP Sbjct: 645 PGP 647 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 80.9 bits (198), Expect = 4e-15 Identities = 80/265 (30%), Positives = 89/265 (33%), Gaps = 48/265 (18%) Query: 453 DKVRKRRKVDEGAGDSAAVASGGAQTLALAG-------SPAPSGHPKAGHSENGVEEDTE 505 D V+ VD+G AV SG A L A P P PK E G E Sbjct: 1208 DSVQTFFAVDDGPSLDQAV-SGLATALCQASFTTQPRPEPCPVYCPKGQKGEPG-EMGLR 1265 Query: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------PRPAGPAGDEPAESP 558 G+ GP G PG P T P P GP G A+ PG P AG G A Sbjct: 1266 GQVGPP-GDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGL 1324 Query: 559 SETPG-PRPAGPAGDEPAESPSETPG-------------------------PSPAGPTRD 592 +PG P P G G+ P PG P P GP D Sbjct: 1325 KGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGD 1384 Query: 593 EPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRD 652 P PG G GD P PGP G A EP P P P GP Sbjct: 1385 PGPRGPPGLPGTAMKGDKGDRGERGP---PGPGEGGIAPGEPG-LPGLPGSPGPQGPV-G 1439 Query: 653 EPAKAGEAAELQDAEVESSAKSGKP 677 P K GE + +D + G P Sbjct: 1440 PPGKKGEKGDSEDGAPGLPGQPGSP 1464 Score = 73.9 bits (180), Expect = 4e-13 Identities = 65/229 (28%), Positives = 82/229 (35%), Gaps = 36/229 (15%) Query: 483 GSPAPSGHP-----KAGHSENGVEEDTEGRTGPK-EGTPGSPSETPGPSPAGPAGDEPAE 536 G P P G P + E G G GP G G P + P P GP GD Sbjct: 1329 GLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPR 1388 Query: 537 SPSETPGPRPAGPAGDE-------PAE---SPSE--------TPGPR-PAGPAGDEPAES 577 P PG G GD P E +P E +PGP+ P GP G + + Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448 Query: 578 PSETPGPSPAGPTRDEPAESPSETPG----------PRPAGPAGDEPAESPSETPGPRP- 626 SE P G + P PG P P G AG++ P G R Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508 Query: 627 AGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675 G AG A+ P PGP+ + EP + G+ A + A + G Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG 1557 Score = 69.7 bits (169), Expect = 8e-12 Identities = 111/419 (26%), Positives = 143/419 (34%), Gaps = 70/419 (16%) Query: 287 GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEA--STQGR--TCGPEHSKG--GGR 340 GP + P PL + + E G PG GR GPE G G + Sbjct: 1471 GPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQ 1530 Query: 341 VDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG 400 ++G R +P GP E G G P + + ++ L P +PG Sbjct: 1531 GEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL----PGDPG 1586 Query: 401 PQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRK 460 P+ ++ + L G A G +G G DPG P P+G R D K Sbjct: 1587 PKG-DPGDRGPIGLTGRAGPPGD--SGPPGEKG-DPGRPGPP--GPVGPRGRDG-EVGEK 1639 Query: 461 VDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPS 519 DEG GD G + L G+P G G G +G PG Sbjct: 1640 GDEGPPGDPGLPGKAGER--GLRGAPGVRG--------------PVGEKGD-QGDPGEDG 1682 Query: 520 ETPGPSPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 578 P +GP GD P PG GP E E P + P GP GD P Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGE-PGDRGQEGPRGPKGD-----P 1736 Query: 579 SETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PRPAGPAG 631 P G P PG R GPAG++ P G P AGP+G Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVR--GPAGEKGDRGPPGLDGRSGLDGKPGAAGPSG 1794 Query: 632 DEPAESPSETPG-------------PSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 A + PG P P+GP P K GE D + + K+G+P Sbjct: 1795 PNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP-GLPGKPGE-----DGKPGLNGKNGEP 1847 Score = 65.1 bits (157), Expect = 2e-10 Identities = 109/384 (28%), Positives = 136/384 (35%), Gaps = 48/384 (12%) Query: 312 EEGSPGDP----------DHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERS 361 + G PGDP D AS + GP+ +G + GPQ P GP + Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGI-LGPQGPPGLPGPVGPPGQG 1901 Query: 362 QGDEAGGHGE--DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN-----L 414 GG G DR E S K + E R +P + P E I + + Sbjct: 1902 FPGVPGGTGPKGDRGETGS-KGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIV 1960 Query: 415 EGCALSQGSLRTGTQEVGGQ--DPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAV 471 E S GS + G D GE P ++ P+G ++ K + D G + Sbjct: 1961 ETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFP-GERGLKGDRGDPGPQGPPGL 2019 Query: 472 A---SGGAQTLALAGSPAPSGHP----------KAGHSENGVEEDTEGRTGP--KEGTPG 516 A G LAG P G P +AG E +G G ++G PG Sbjct: 2020 ALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG 2079 Query: 517 SPSETPGPSPAGP--AGDEPAESPSETPGPRPAGPAGDEPAESPSETP-GPRPA-GPAGD 572 P P P GP + DEP S GP A EP + + P G R G GD Sbjct: 2080 LPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGD 2139 Query: 573 EPAESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PRPAGP 629 P G P G E GPR P GP G P PG PAGP Sbjct: 2140 RGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGP 2199 Query: 630 AGDEPAE-SPSET--PGPSPAGPT 650 G + P ET PG GPT Sbjct: 2200 QGPSGLKGEPGETGPPGRGLTGPT 2223 Score = 63.9 bits (154), Expect = 5e-10 Identities = 111/411 (27%), Positives = 134/411 (32%), Gaps = 118/411 (28%) Query: 312 EEGSPGDPDHEASTQGRTCGPEHSKG-----------GGRVDEGPQPRSVEPQDAGPLER 360 E+G PG P A GP+ KG G + + GP P V P D GP + Sbjct: 1532 EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGP-PGLVLPGDPGP-KG 1589 Query: 361 SQGD--------------EAGGHGED----RPEPLSPKESKKRKLELSRR--EQPPTEPG 400 GD ++G GE RP P P + R E+ + E PP +PG Sbjct: 1590 DPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG 1649 Query: 401 -PQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQ-DPGEAVQPCRQPLGARVADKVRKR 458 P A E L G +R E G Q DPGE Sbjct: 1650 LPGKAGE-----RGLRGAP----GVRGPVGEKGDQGDPGE-------------------- 1680 Query: 459 RKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKA------GHSENGVEEDT--EGRTGP 510 D + G + G P P G P G E G D EG GP Sbjct: 1681 --------DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGP 1732 Query: 511 K--EGTPGSPSETPGPS---PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR 565 K G PG+P E P GP GD P+ G R GP G + PG Sbjct: 1733 KGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDR--GPPGLDGRSGLDGKPGA- 1789 Query: 566 PAGPAGDEPAESPSETPG-------------PSPAGP--TRDEPAE-----------SPS 599 AGP+G A + PG P P+GP +P E P Sbjct: 1790 -AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPG 1848 Query: 600 ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPAGP 649 + G GD A GP+ G G P PG P P GP Sbjct: 1849 DPGEDGRKGEKGDSGASGREGRDGPK--GERGAPGILGPQGPPGLPGPVGP 1897 Score = 60.8 bits (146), Expect = 4e-09 Identities = 106/390 (27%), Positives = 138/390 (35%), Gaps = 59/390 (15%) Query: 310 VEEEGSPGDPDHEASTQGRTCGPEHS-KGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGG 368 V E+G GDP + GR P S G R + GP D GP R +G E G Sbjct: 1669 VGEKGDQGDPGED----GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKG-EPGD 1723 Query: 369 HGEDRP-----EPLSPKESKKRKLELSRREQPPT-EPGPQ--SASEVEKIALNLEGCALS 420 G++ P +P P +R +E R P +PG + + + ++ L+G + Sbjct: 1724 RGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGL 1783 Query: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTL- 479 G G+A P R L +R + + +G G Sbjct: 1784 DGKPGAAGPSGPNGAAGKAGDPGRDGLPG-----LRGEQGLPGPSGPPGLPGKPGEDGKP 1838 Query: 480 ALAGSPAPSGHP----KAGHSENGVEEDTEGRTGPK--EGTPG--SPSETPG-PSPAGPA 530 L G G P + G + EGR GPK G PG P PG P P GP Sbjct: 1839 GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPP 1898 Query: 531 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS-----ETPGPS 585 G P G P G G+ ++ PG R G G EP P+ ET G Sbjct: 1899 GQG---FPGVPGGTGPKGDRGETGSKGEQGLPGER--GLRG-EPGSVPNVDRLLETAGIK 1952 Query: 586 PAG-----PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PRPAGPAGDEPAE 636 + T DE + S P R GP GD + P G P G GD Sbjct: 1953 ASALREIVETWDESSGSFLPVP-ERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDP 2011 Query: 637 SPSETPG--------PSPAGPTRDEPAKAG 658 P PG P P+G EP K G Sbjct: 2012 GPQGPPGLALGERGPPGPSG-LAGEPGKPG 2040 Score = 60.8 bits (146), Expect = 4e-09 Identities = 105/401 (26%), Positives = 123/401 (30%), Gaps = 75/401 (18%) Query: 287 GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346 GP+ K P P P+ G G PG P A GP+ GP Sbjct: 2162 GPEGKPGLQGPRGPPGPVGG------HGDPGPPG--APGLAGPAGPQ----------GPS 2203 Query: 347 PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG-PQSAS 405 EP + GP R G G P P P S P PG P Sbjct: 2204 GLKGEPGETGPPGRGLTGPTGAVG--LPGPPGP----------SGLVGPQGSPGLPGQVG 2251 Query: 406 EVEKI-ALNLEGCALSQGSLRTGTQEVGGQ-----------DPGEAVQPCRQPLGARVAD 453 E K A +G + G G+ V G +PG P + +G A Sbjct: 2252 ETGKPGAPGRDGASGKDGD--RGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGA- 2308 Query: 454 KVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKE 512 K ++GA G A G G P P G E+ GR G + Sbjct: 2309 ------KGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG-----------EKGEAGRAG-EP 2350 Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PRPAG 568 G PG + P P G GD P P P G GD PG P G Sbjct: 2351 GDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTG 2410 Query: 569 PAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG-PRPAGPAGDEPAESPSETPG---P 624 P G+ PS G AGP E P PG P GP G + PG P Sbjct: 2411 PRGEMGQPGPSGERG--LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLP 2468 Query: 625 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQD 665 P G G+ PG P GE E D Sbjct: 2469 GPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGD 2509 Score = 57.0 bits (136), Expect = 6e-08 Identities = 63/220 (28%), Positives = 78/220 (35%), Gaps = 30/220 (13%) Query: 483 GSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPGSPSET-----------PGP-SP 526 G P +G PK G++ D G GP+ +G PG P E GP P Sbjct: 2117 GEPGSNGDQGPKGDRGVPGIKGD-RGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGP 2175 Query: 527 AGPAGDEPAESPSETPG-PRPAGPAGDEPAES-PSETPGPR-----PAGPAGDEPAESPS 579 GP G P PG PAGP G + P ET P P G G PS Sbjct: 2176 PGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS 2235 Query: 580 ETPGP--SPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAE 636 GP SP P + P +G GD + +PG P P GP G+ Sbjct: 2236 GLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEP--- 2292 Query: 637 SPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGK 676 P+ PG + G + K D E AK + Sbjct: 2293 GPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDR 2332 Score = 54.3 bits (129), Expect = 4e-07 Identities = 98/370 (26%), Positives = 125/370 (33%), Gaps = 74/370 (20%) Query: 313 EGSPGDPDHEASTQGRTCGPEHSKG--GGRVDEG-PQPRSVEPQDAGPLERSQGDEAGGH 369 +G+ G+P GP+ +G G + D G P PR + P ER G Sbjct: 2113 KGAKGEPGSNGDQ-----GPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKP 2167 Query: 370 GEDRPE-PLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGT 428 G P P P +PGP A L G A QG +G Sbjct: 2168 GLQGPRGPPGPVGGHG-------------DPGPPGAP-------GLAGPAGPQGP--SGL 2205 Query: 429 QEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPS 488 + +PGE P R G A + G S V G+ L G + Sbjct: 2206 KG----EPGETGPPGRGLTGPTGAVGL------PGPPGPSGLVGPQGSP--GLPGQVGET 2253 Query: 489 GHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR--- 545 G P A + +D + + G+PG P GP G P ++ PG + Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTG-APGQAVVGLPGAKGEK 2312 Query: 546 --PAGPAGD---EP-AESPSETPGPR----PAGPAGD--EPAESPSETPGPSPAGPTRDE 593 P G AGD EP A+ PGPR AG AG+ +P E + P P G D Sbjct: 2313 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGED-GQKGAPGPKGFKGDP 2371 Query: 594 PAESPSETPGPRPAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPG------ 643 P P P G GD PG P GP G+ PS G Sbjct: 2372 GVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431 Query: 644 ----PSPAGP 649 P P GP Sbjct: 2432 REGIPGPLGP 2441 Score = 52.0 bits (123), Expect = 2e-06 Identities = 57/198 (28%), Positives = 71/198 (35%), Gaps = 23/198 (11%) Query: 483 GSPAPSGHPKAGHSENGV----EEDTEGRTGPK-----EGTPGSPSETPGPSPAGPAGDE 533 GSP G P + V +G G K +G G E P G AG + Sbjct: 2599 GSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHK 2658 Query: 534 PAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG----PSPAG 588 PG +G G E P G GP GD+ + TPG P P+G Sbjct: 2659 GEMGEPGVPGQ--SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSG 2716 Query: 589 PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPA 647 P + GPR GP G + + PG R G G A G P PA Sbjct: 2717 NDGSAGPPGPPGSVGPR--GPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774 Query: 648 GPTRDEPAKAGEAAELQD 665 GP ++ GEAA +D Sbjct: 2775 GPRGEK----GEAALTED 2788 Score = 50.8 bits (120), Expect = 4e-06 Identities = 113/441 (25%), Positives = 138/441 (31%), Gaps = 108/441 (24%) Query: 312 EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDE-----A 366 E+G PGD E GP KG + P R +E P QGD A Sbjct: 1717 EKGEPGDRGQE--------GPRGPKGDPGLPGAPGERGIEGFRGPP--GPQGDPGVRGPA 1766 Query: 367 GGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR- 425 G G+ P L + L+ P+ P + + L G QG Sbjct: 1767 GEKGDRGPPGLDGRSG----LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGP 1822 Query: 426 TGTQEVGGQDPGEAVQPCRQPLGARVADKV---RKRRKVDEGA----------GDSAAVA 472 +G + G+ PGE +P D RK K D GA G+ A Sbjct: 1823 SGPPGLPGK-PGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG 1881 Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPA 530 G Q G P P G P G G TGPK G GS E P G Sbjct: 1882 ILGPQ--GPPGLPGPVGPPGQGFP------GVPGGTGPKGDRGETGSKGEQGLPGERGLR 1933 Query: 531 GDEPAESPS-----ETPG------------------------PRPAGPAGDEPAESPSET 561 G EP P+ ET G R GP GD + P Sbjct: 1934 G-EPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGK 1992 Query: 562 PGP----RPAGPAGDEPAESPSETPGPS-----PAGPT--RDEPAE-------------S 597 GP G GD P PG + P GP+ EP + Sbjct: 1993 EGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVG 2052 Query: 598 PSETPGPR----PAGPAGDEPAESPSETPG-PRPAGPAG-----DEPAESPSETPGPSPA 647 + PG R G G++ + P PG P P GP G DEP S GP Sbjct: 2053 EAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL 2112 Query: 648 GPTRDEPAKAGEAAELQDAEV 668 + EP G+ D V Sbjct: 2113 KGAKGEPGSNGDQGPKGDRGV 2133 Score = 38.1 bits (87), Expect = 0.027 Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 8/143 (5%) Query: 435 DPGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKA 493 D GEA P R L + GA G + G + G P P G + Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR--GFDGQPGPKGD-QG 2698 Query: 494 GHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAG 551 E G G GP +G+ G P P GP G + + PG R G G Sbjct: 2699 EKGERGTP-GIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPG 2757 Query: 552 DEPAESPSETPG-PRPAGPAGDE 573 A G P PAGP G++ Sbjct: 2758 VPGAPGERGEQGRPGPAGPRGEK 2780 Score = 32.0 bits (71), Expect = 1.9 Identities = 58/246 (23%), Positives = 80/246 (32%), Gaps = 50/246 (20%) Query: 312 EEGSPGDPDHEASTQ----GRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAG 367 ++GS G+P + S GP+ G + P +D P R + + G Sbjct: 2561 DKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG---KDGVPGIRGEKGDVG 2617 Query: 368 GHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTG 427 G P L + K L + E GP G A +G + G Sbjct: 2618 FMG---PRGLKGERGVKGACGLDGEKGDKGEAGPPGRP----------GLAGHKGEM--G 2662 Query: 428 TQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAP 487 V GQ + P G R D + K D+G G T + G P P Sbjct: 2663 EPGVPGQSGAPGKEGLIGPKGDRGFDG-QPGPKGDQGE-------KGERGTPGIGGFPGP 2714 Query: 488 SGH--------PKAGHSENGVE--EDTEGRTGPK----------EGTPGSPSETPGPSPA 527 SG+ P G E + +G GP G PG E P PA Sbjct: 2715 SGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774 Query: 528 GPAGDE 533 GP G++ Sbjct: 2775 GPRGEK 2780 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 79.7 bits (195), Expect = 8e-15 Identities = 112/381 (29%), Positives = 139/381 (36%), Gaps = 63/381 (16%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKGGGRVDEGPQPRSVEPQD 354 P P P ++G PG P T QG+T P G G V GPQ + E Sbjct: 938 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP----GPGGV-VGPQGPTGE--- 989 Query: 355 AGPL-ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN 413 GP+ ER G GE + KE K +PGPQ S + A Sbjct: 990 TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG------------DPGPQGISGKDGPA-G 1036 Query: 414 LEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473 L G +G G Q G GE Q P+G+ G SA Sbjct: 1037 LRGFPGERGL--PGAQGAPGLKGGEGPQGPPGPVGS-------------PGERGSA---- 1077 Query: 474 GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS-PAGPAG 531 G A + L G P P G P AG E+ +G G ++G G P PGP+ PAG G Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQG-PVGLPGPAGPAGSPG 1135 Query: 532 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----SPA 587 ++ + PG + G GD+ P PG + GP G PGP Sbjct: 1136 EDGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEPGPRGQQGMF 1191 Query: 588 GPTRDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 639 G DE A PG P P G G+ P PG P P GP G A+ P Sbjct: 1192 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1251 Query: 640 ETPGPSPAGPTRDEPAKAGEA 660 PG + E + GEA Sbjct: 1252 GPPGSVGSVGGVGEKGEPGEA 1272 Score = 69.7 bits (169), Expect = 8e-12 Identities = 121/422 (28%), Positives = 150/422 (35%), Gaps = 80/422 (18%) Query: 310 VEEEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLER--- 360 + E G PG P QG G E +KG D GPQ S + AG P ER Sbjct: 993 IGERGHPGPPGPPGE-QGLPGAAGKEGAKG----DPGPQGISGKDGPAGLRGFPGERGLP 1047 Query: 361 -SQGDEAGGHGEDRPEPLSPKESKKRK--------LELSRREQPPTEPGPQSASEVEKIA 411 +QG GE P P S + + L R P PGP EK A Sbjct: 1048 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG----EKGA 1103 Query: 412 LNLEGCALSQGSLRTGTQ-EVGGQDP-GEAVQPCRQPLGARVADKVRKRRKVDEGA---- 465 +G G R G Q VG P G A P + + +K K D+G Sbjct: 1104 PGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1161 Query: 466 GDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPS 519 G GA +A G P P G + G +E G GP +G PG P Sbjct: 1162 GPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219 Query: 520 ETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESP 578 E GP G P PGPR GP G A+ P PG G G++ Sbjct: 1220 EKGENGDVGPMG------PPGPPGPR--GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1271 Query: 579 SETPGP-------SPAGPTRDEPAESPSETPGPRPA-GPAGDE-PAESPSETPGPRPAGP 629 + PGP P G ++ P GP A GP GD+ P +P P GP Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1331 Query: 630 AGDEPAESPSETPG-----------PSPAGPTRD-----EPAKAGE--AAELQDAEVESS 671 G EP + + G P P GP+ + P K G AA + + E Sbjct: 1332 PG-EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1390 Query: 672 AK 673 AK Sbjct: 1391 AK 1392 Score = 69.3 bits (168), Expect = 1e-11 Identities = 98/359 (27%), Positives = 120/359 (33%), Gaps = 77/359 (21%) Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQS-ASEVEKIAL-NLEG 416 +R + + G GED PE PK R P +PGP A E K+ + L G Sbjct: 809 DRGEVGQIGPRGEDGPE--GPKG----------RAGPTGDPGPSGQAGEKGKLGVPGLPG 856 Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 QG + G G+ V P G R R R G Sbjct: 857 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916 Query: 473 SGGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGP--KEGTPGSPSET------- 521 + G G P P G P+ G +G GP K+G PG P + Sbjct: 917 TSGGD-----GPPGPPGERGPQGPQGPVGFP-GPKGPPGPPGKDGLPGHPGQRGETGFQG 970 Query: 522 ----PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPA------ESPSETPGPRPA 567 PGP P GP G+ PGP GP G++ E PGP+ Sbjct: 971 KTGPPGPGGVVGPQGPTGETGPIGERGHPGP--PGPPGEQGLPGAAGKEGAKGDPGPQGI 1028 Query: 568 ----GPAGDE--PAE--------SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613 GPAG P E +P G P GP P SP E AGP G Sbjct: 1029 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGPIGLP 1086 Query: 614 PAESPSETPGPR----------PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662 P PGP P GPAG + + P PGP+ + E GE E Sbjct: 1087 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145 Score = 68.2 bits (165), Expect = 2e-11 Identities = 113/424 (26%), Positives = 145/424 (34%), Gaps = 65/424 (15%) Query: 288 PQDKLRRFK--PSSLPHPL--EGSRKVEEEGSPGDPDHEASTQGR-----TCGPEHSKGG 338 P DK R + P P P +G R + E P EA +G T G G Sbjct: 621 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680 Query: 339 GRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPK-----ESKKRKLELSRR 392 VD P P+ P Q G G P+ P+ P + K L Sbjct: 681 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 740 Query: 393 EQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLGARV 451 + PP PG + S EK AL G QG + G + V G D ++ + G Sbjct: 741 DGPPGHPGKEGQSG-EKGALGPPG---PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 796 Query: 452 ADKVRKRRKVDEGAGDSAAVASGGAQ-------TLALAGSPAPSGHPKAGHSEN-GVE-- 501 + + G+ + G G P PSG +AG GV Sbjct: 797 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG--QAGEKGKLGVPGL 854 Query: 502 EDTEGRTGPKEGT--PGSPSET-----------PGP----SPAGPAGDEPAESPSETPGP 544 GR GPK T PG P PGP P GP G A P+ PGP Sbjct: 855 PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 914 Query: 545 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSE 600 + GD P P E P GP G + P PG P G + + + Sbjct: 915 KGTS-GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973 Query: 601 TPGP----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPT-R 651 PGP P GP G+ PG P GP G++ + G P P G + + Sbjct: 974 PPGPGGVVGPQGPTGETGPIGERGHPG--PPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031 Query: 652 DEPA 655 D PA Sbjct: 1032 DGPA 1035 Score = 66.6 bits (161), Expect = 7e-11 Identities = 100/367 (27%), Positives = 128/367 (34%), Gaps = 56/367 (15%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373 GSPG+ D + G G + SKG + P P ++ P AGG GE Sbjct: 1132 GSPGE-DGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP------GIAGGDGE-- 1181 Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433 P P + +K + R P PGP + L+G G + +VG Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGP-PGP----------IGLQGLPGPPGE-KGENGDVGP 1229 Query: 434 QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGH--- 490 P P R P G AD + G V G AG+P P G Sbjct: 1230 MGPPGPPGP-RGPQGPNGADGPQGP---PGSVGSVGGVGEKGEP--GEAGNPGPPGEAGV 1283 Query: 491 --PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP 546 PK E G E G GP +G PG P P G GD P P P Sbjct: 1284 GGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-----PGPPGEPGP 1337 Query: 547 AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE--SPSETPG 603 AG G + PG P P GP+G+ P GP A E + E Sbjct: 1338 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1397 Query: 604 PRPAGPAGDEPAESPSETPGPRP----AGPAGDE--PAESPSETPGPSPAGP-----TRD 652 P G G + P+ PGP GP G++ P + + P P P GP + Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKG 1456 Query: 653 EPAKAGE 659 +P GE Sbjct: 1457 DPGSKGE 1463 Score = 65.5 bits (158), Expect = 2e-10 Identities = 61/211 (28%), Positives = 77/211 (36%), Gaps = 28/211 (13%) Query: 479 LALAGSPAPSGHPKA----GHSENGVEEDTEGRTGP--------KEGTPGSPSETPGPSP 526 + L G P P G P + G S + + G GP K G PG+ P Sbjct: 546 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 605 Query: 527 AGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRPA-GPAGDEPA 575 G GD + PG + P GP GD+ GPR G AG Sbjct: 606 PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 665 Query: 576 ESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR-PAGPAGD 632 P TPG P G + P GP+ GP G + P PGP+ P GP G+ Sbjct: 666 LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 725 Query: 633 E-PAESPSETPGPSPAGPTRDEPAKAGEAAE 662 + P P P GP P K G++ E Sbjct: 726 KGPQGKPGLAGLPGADGPP-GHPGKEGQSGE 755 Score = 65.1 bits (157), Expect = 2e-10 Identities = 114/439 (25%), Positives = 145/439 (33%), Gaps = 105/439 (23%) Query: 312 EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371 E G PG P + GP + G D P PR + +GDE Sbjct: 1157 ENGPPGPPGLQ--------GPVGAPGIAGGDGEPGPRGQQGMFG-----QKGDEGARGFP 1203 Query: 372 DRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR 425 P P+ P K ++ PP PGP+ A +G S GS+ Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMG-PPGPPGPRGPQGPNG-ADGPQGPPGSVGSVG 1261 Query: 426 TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-------- 477 G E G +PGEA P P G + R AG A GA+ Sbjct: 1262 -GVGEKG--EPGEAGNP--GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1316 Query: 478 -----TLALAGSPAPSGHPKAGHSENGV-----EEDTEGRTGP-----KEGTPGSPSETP 522 + G P P G P ++GV E+ G+ GP + G PG P + Sbjct: 1317 KGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1375 Query: 523 GPSPAGPAG---------DEPAESPSETPGP-RPAGPAGDEPAESPSETPGP-------- 564 P AG G + AE P GP P GPAG E PGP Sbjct: 1376 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1435 Query: 565 --------RPAGPAG------DEPAESPSETPG-------PSPAGPTRDEPAESPSETPG 603 P GP G D ++ PG P G D +PG Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1495 Query: 604 -------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655 P PAGP G P PG P P GP G++ + P+ G S P Sbjct: 1496 AKGDGGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Query: 656 KAGEAAELQDAEVESSAKS 674 GE +Q + SS K+ Sbjct: 1550 PPGEV--IQPLPILSSKKT 1566 Score = 61.2 bits (147), Expect = 3e-09 Identities = 95/365 (26%), Positives = 121/365 (33%), Gaps = 81/365 (22%) Query: 287 GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346 GPQ P P + V E+G PG+ + GP G G GP+ Sbjct: 1240 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP--------GPPGEAGVG----GPK 1287 Query: 347 PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASE 406 E +AGP AG G P + + PP EPGP Sbjct: 1288 GERGEKGEAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ-- 1340 Query: 407 VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPC----RQPLGARVADKVRKRRKVD 462 +G +G Q GEA P R P GA A+ R+ + Sbjct: 1341 --------DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG----RQGE 1388 Query: 463 EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSE 520 +GA A A G G P+G P E G GP ++G PG+ + Sbjct: 1389 KGAKGEAG-AEGPPGKTGPVGPQGPAGKPGP--------EGLRGIPGPVGEQGLPGAAGQ 1439 Query: 521 TPGPSPAGPAG------DEPAESPSETPG-------PRPAGPAGDEPAESPSETPG---- 563 P P GP G D ++ PG P G GD +PG Sbjct: 1440 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1499 Query: 564 ---PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPS 619 P PAGP G P PG P P GP ++ + P AG GD P Sbjct: 1500 GGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGP--------AGQKGDSGLPGPP 1545 Query: 620 ETPGP 624 +PGP Sbjct: 1546 GSPGP 1550 Score = 50.8 bits (120), Expect = 4e-06 Identities = 52/184 (28%), Positives = 62/184 (33%), Gaps = 49/184 (26%) Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG--------- 563 G PG T P P G G A+ S PGP+ GP G + P+ PG Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ--GPRGVQGPPGPTGKPGKRGRPGADG 598 Query: 564 ----PRPAGPAGDEPAESPSETPG----------PSPAGPTRDE--------------PA 595 P G GD + PG P GP D+ P Sbjct: 599 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 658 Query: 596 ES-------PSETPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-S 645 E+ P TPG P G AG + P GP+ GP G + P PGP Sbjct: 659 EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718 Query: 646 PAGP 649 P GP Sbjct: 719 PIGP 722 Score = 45.1 bits (105), Expect = 2e-04 Identities = 56/192 (29%), Positives = 68/192 (35%), Gaps = 31/192 (16%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 G PA + + + +G + + P PG E P P PAGPAG P Sbjct: 416 GVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP-PGPAGPAG---IMGPPGLQ 471 Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES---PSETPGPSPAGPTRD-EPAESP 598 GP GP GD P PG A P P G GPT + A++ Sbjct: 472 GP--TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 529 Query: 599 SETPGPR-----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-------SP 646 + R P GP G T P P G G A+ S PGP P Sbjct: 530 AILQQARIALRGPPGPMG--------LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 581 Query: 647 AGPTRDEPAKAG 658 GPT +P K G Sbjct: 582 PGPT-GKPGKRG 592 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 79.7 bits (195), Expect = 8e-15 Identities = 112/381 (29%), Positives = 139/381 (36%), Gaps = 63/381 (16%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKGGGRVDEGPQPRSVEPQD 354 P P P ++G PG P T QG+T P G G V GPQ + E Sbjct: 887 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP----GPGGV-VGPQGPTGE--- 938 Query: 355 AGPL-ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN 413 GP+ ER G GE + KE K +PGPQ S + A Sbjct: 939 TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG------------DPGPQGISGKDGPA-G 985 Query: 414 LEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473 L G +G G Q G GE Q P+G+ G SA Sbjct: 986 LRGFPGERGL--PGAQGAPGLKGGEGPQGPPGPVGS-------------PGERGSA---- 1026 Query: 474 GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS-PAGPAG 531 G A + L G P P G P AG E+ +G G ++G G P PGP+ PAG G Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQG-PVGLPGPAGPAGSPG 1084 Query: 532 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----SPA 587 ++ + PG + G GD+ P PG + GP G PGP Sbjct: 1085 EDGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEPGPRGQQGMF 1140 Query: 588 GPTRDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 639 G DE A PG P P G G+ P PG P P GP G A+ P Sbjct: 1141 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200 Query: 640 ETPGPSPAGPTRDEPAKAGEA 660 PG + E + GEA Sbjct: 1201 GPPGSVGSVGGVGEKGEPGEA 1221 Score = 69.7 bits (169), Expect = 8e-12 Identities = 121/422 (28%), Positives = 150/422 (35%), Gaps = 80/422 (18%) Query: 310 VEEEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLER--- 360 + E G PG P QG G E +KG D GPQ S + AG P ER Sbjct: 942 IGERGHPGPPGPPGE-QGLPGAAGKEGAKG----DPGPQGISGKDGPAGLRGFPGERGLP 996 Query: 361 -SQGDEAGGHGEDRPEPLSPKESKKRK--------LELSRREQPPTEPGPQSASEVEKIA 411 +QG GE P P S + + L R P PGP EK A Sbjct: 997 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG----EKGA 1052 Query: 412 LNLEGCALSQGSLRTGTQ-EVGGQDP-GEAVQPCRQPLGARVADKVRKRRKVDEGA---- 465 +G G R G Q VG P G A P + + +K K D+G Sbjct: 1053 PGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1110 Query: 466 GDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPS 519 G GA +A G P P G + G +E G GP +G PG P Sbjct: 1111 GPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168 Query: 520 ETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESP 578 E GP G P PGPR GP G A+ P PG G G++ Sbjct: 1169 EKGENGDVGPMG------PPGPPGPR--GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1220 Query: 579 SETPGP-------SPAGPTRDEPAESPSETPGPRPA-GPAGDE-PAESPSETPGPRPAGP 629 + PGP P G ++ P GP A GP GD+ P +P P GP Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1280 Query: 630 AGDEPAESPSETPG-----------PSPAGPTRD-----EPAKAGE--AAELQDAEVESS 671 G EP + + G P P GP+ + P K G AA + + E Sbjct: 1281 PG-EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1339 Query: 672 AK 673 AK Sbjct: 1340 AK 1341 Score = 69.3 bits (168), Expect = 1e-11 Identities = 98/359 (27%), Positives = 120/359 (33%), Gaps = 77/359 (21%) Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQS-ASEVEKIAL-NLEG 416 +R + + G GED PE PK R P +PGP A E K+ + L G Sbjct: 758 DRGEVGQIGPRGEDGPE--GPKG----------RAGPTGDPGPSGQAGEKGKLGVPGLPG 805 Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 QG + G G+ V P G R R R G Sbjct: 806 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865 Query: 473 SGGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGP--KEGTPGSPSET------- 521 + G G P P G P+ G +G GP K+G PG P + Sbjct: 866 TSGGD-----GPPGPPGERGPQGPQGPVGFP-GPKGPPGPPGKDGLPGHPGQRGETGFQG 919 Query: 522 ----PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPA------ESPSETPGPRPA 567 PGP P GP G+ PGP GP G++ E PGP+ Sbjct: 920 KTGPPGPGGVVGPQGPTGETGPIGERGHPGP--PGPPGEQGLPGAAGKEGAKGDPGPQGI 977 Query: 568 ----GPAGDE--PAE--------SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613 GPAG P E +P G P GP P SP E AGP G Sbjct: 978 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGPIGLP 1035 Query: 614 PAESPSETPGPR----------PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662 P PGP P GPAG + + P PGP+ + E GE E Sbjct: 1036 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094 Score = 68.2 bits (165), Expect = 2e-11 Identities = 113/424 (26%), Positives = 145/424 (34%), Gaps = 65/424 (15%) Query: 288 PQDKLRRFK--PSSLPHPL--EGSRKVEEEGSPGDPDHEASTQGR-----TCGPEHSKGG 338 P DK R + P P P +G R + E P EA +G T G G Sbjct: 570 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629 Query: 339 GRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPK-----ESKKRKLELSRR 392 VD P P+ P Q G G P+ P+ P + K L Sbjct: 630 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 689 Query: 393 EQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLGARV 451 + PP PG + S EK AL G QG + G + V G D ++ + G Sbjct: 690 DGPPGHPGKEGQSG-EKGALGPPG---PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745 Query: 452 ADKVRKRRKVDEGAGDSAAVASGGAQ-------TLALAGSPAPSGHPKAGHSEN-GVE-- 501 + + G+ + G G P PSG +AG GV Sbjct: 746 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG--QAGEKGKLGVPGL 803 Query: 502 EDTEGRTGPKEGT--PGSPSET-----------PGP----SPAGPAGDEPAESPSETPGP 544 GR GPK T PG P PGP P GP G A P+ PGP Sbjct: 804 PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 863 Query: 545 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSE 600 + GD P P E P GP G + P PG P G + + + Sbjct: 864 KGTS-GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922 Query: 601 TPGP----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPT-R 651 PGP P GP G+ PG P GP G++ + G P P G + + Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPG--PPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980 Query: 652 DEPA 655 D PA Sbjct: 981 DGPA 984 Score = 66.6 bits (161), Expect = 7e-11 Identities = 100/367 (27%), Positives = 128/367 (34%), Gaps = 56/367 (15%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373 GSPG+ D + G G + SKG + P P ++ P AGG GE Sbjct: 1081 GSPGE-DGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP------GIAGGDGE-- 1130 Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433 P P + +K + R P PGP + L+G G + +VG Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGP-PGP----------IGLQGLPGPPGE-KGENGDVGP 1178 Query: 434 QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGH--- 490 P P R P G AD + G V G AG+P P G Sbjct: 1179 MGPPGPPGP-RGPQGPNGADGPQGP---PGSVGSVGGVGEKGEP--GEAGNPGPPGEAGV 1232 Query: 491 --PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP 546 PK E G E G GP +G PG P P G GD P P P Sbjct: 1233 GGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-----PGPPGEPGP 1286 Query: 547 AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE--SPSETPG 603 AG G + PG P P GP+G+ P GP A E + E Sbjct: 1287 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1346 Query: 604 PRPAGPAGDEPAESPSETPGPRP----AGPAGDE--PAESPSETPGPSPAGP-----TRD 652 P G G + P+ PGP GP G++ P + + P P P GP + Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKG 1405 Query: 653 EPAKAGE 659 +P GE Sbjct: 1406 DPGSKGE 1412 Score = 65.5 bits (158), Expect = 2e-10 Identities = 61/211 (28%), Positives = 77/211 (36%), Gaps = 28/211 (13%) Query: 479 LALAGSPAPSGHPKA----GHSENGVEEDTEGRTGP--------KEGTPGSPSETPGPSP 526 + L G P P G P + G S + + G GP K G PG+ P Sbjct: 495 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 554 Query: 527 AGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRPA-GPAGDEPA 575 G GD + PG + P GP GD+ GPR G AG Sbjct: 555 PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 614 Query: 576 ESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR-PAGPAGD 632 P TPG P G + P GP+ GP G + P PGP+ P GP G+ Sbjct: 615 LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 674 Query: 633 E-PAESPSETPGPSPAGPTRDEPAKAGEAAE 662 + P P P GP P K G++ E Sbjct: 675 KGPQGKPGLAGLPGADGPP-GHPGKEGQSGE 704 Score = 65.1 bits (157), Expect = 2e-10 Identities = 114/439 (25%), Positives = 145/439 (33%), Gaps = 105/439 (23%) Query: 312 EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371 E G PG P + GP + G D P PR + +GDE Sbjct: 1106 ENGPPGPPGLQ--------GPVGAPGIAGGDGEPGPRGQQGMFG-----QKGDEGARGFP 1152 Query: 372 DRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR 425 P P+ P K ++ PP PGP+ A +G S GS+ Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMG-PPGPPGPRGPQGPNG-ADGPQGPPGSVGSVG 1210 Query: 426 TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-------- 477 G E G +PGEA P P G + R AG A GA+ Sbjct: 1211 -GVGEKG--EPGEAGNP--GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1265 Query: 478 -----TLALAGSPAPSGHPKAGHSENGV-----EEDTEGRTGP-----KEGTPGSPSETP 522 + G P P G P ++GV E+ G+ GP + G PG P + Sbjct: 1266 KGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1324 Query: 523 GPSPAGPAG---------DEPAESPSETPGP-RPAGPAGDEPAESPSETPGP-------- 564 P AG G + AE P GP P GPAG E PGP Sbjct: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384 Query: 565 --------RPAGPAG------DEPAESPSETPG-------PSPAGPTRDEPAESPSETPG 603 P GP G D ++ PG P G D +PG Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444 Query: 604 -------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655 P PAGP G P PG P P GP G++ + P+ G S P Sbjct: 1445 AKGDGGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Query: 656 KAGEAAELQDAEVESSAKS 674 GE +Q + SS K+ Sbjct: 1499 PPGEV--IQPLPILSSKKT 1515 Score = 61.2 bits (147), Expect = 3e-09 Identities = 95/365 (26%), Positives = 121/365 (33%), Gaps = 81/365 (22%) Query: 287 GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346 GPQ P P + V E+G PG+ + GP G G GP+ Sbjct: 1189 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP--------GPPGEAGVG----GPK 1236 Query: 347 PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASE 406 E +AGP AG G P + + PP EPGP Sbjct: 1237 GERGEKGEAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ-- 1289 Query: 407 VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPC----RQPLGARVADKVRKRRKVD 462 +G +G Q GEA P R P GA A+ R+ + Sbjct: 1290 --------DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG----RQGE 1337 Query: 463 EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSE 520 +GA A A G G P+G P E G GP ++G PG+ + Sbjct: 1338 KGAKGEAG-AEGPPGKTGPVGPQGPAGKPGP--------EGLRGIPGPVGEQGLPGAAGQ 1388 Query: 521 TPGPSPAGPAG------DEPAESPSETPG-------PRPAGPAGDEPAESPSETPG---- 563 P P GP G D ++ PG P G GD +PG Sbjct: 1389 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1448 Query: 564 ---PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPS 619 P PAGP G P PG P P GP ++ + P AG GD P Sbjct: 1449 GGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGP--------AGQKGDSGLPGPP 1494 Query: 620 ETPGP 624 +PGP Sbjct: 1495 GSPGP 1499 Score = 50.8 bits (120), Expect = 4e-06 Identities = 52/184 (28%), Positives = 62/184 (33%), Gaps = 49/184 (26%) Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG--------- 563 G PG T P P G G A+ S PGP+ GP G + P+ PG Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ--GPRGVQGPPGPTGKPGKRGRPGADG 547 Query: 564 ----PRPAGPAGDEPAESPSETPG----------PSPAGPTRDE--------------PA 595 P G GD + PG P GP D+ P Sbjct: 548 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 607 Query: 596 ES-------PSETPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-S 645 E+ P TPG P G AG + P GP+ GP G + P PGP Sbjct: 608 EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667 Query: 646 PAGP 649 P GP Sbjct: 668 PIGP 671 Score = 45.1 bits (105), Expect = 2e-04 Identities = 56/192 (29%), Positives = 68/192 (35%), Gaps = 31/192 (16%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 G PA + + + +G + + P PG E P P PAGPAG P Sbjct: 365 GVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP-PGPAGPAG---IMGPPGLQ 420 Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES---PSETPGPSPAGPTRD-EPAESP 598 GP GP GD P PG A P P G GPT + A++ Sbjct: 421 GP--TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 478 Query: 599 SETPGPR-----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-------SP 646 + R P GP G T P P G G A+ S PGP P Sbjct: 479 AILQQARIALRGPPGPMG--------LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 530 Query: 647 AGPTRDEPAKAG 658 GPT +P K G Sbjct: 531 PGPT-GKPGKRG 541 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 79.7 bits (195), Expect = 8e-15 Identities = 112/381 (29%), Positives = 139/381 (36%), Gaps = 63/381 (16%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKGGGRVDEGPQPRSVEPQD 354 P P P ++G PG P T QG+T P G G V GPQ + E Sbjct: 926 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP----GPGGV-VGPQGPTGE--- 977 Query: 355 AGPL-ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN 413 GP+ ER G GE + KE K +PGPQ S + A Sbjct: 978 TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG------------DPGPQGISGKDGPA-G 1024 Query: 414 LEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473 L G +G G Q G GE Q P+G+ G SA Sbjct: 1025 LRGFPGERGL--PGAQGAPGLKGGEGPQGPPGPVGS-------------PGERGSA---- 1065 Query: 474 GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS-PAGPAG 531 G A + L G P P G P AG E+ +G G ++G G P PGP+ PAG G Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQG-PVGLPGPAGPAGSPG 1123 Query: 532 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----SPA 587 ++ + PG + G GD+ P PG + GP G PGP Sbjct: 1124 EDGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEPGPRGQQGMF 1179 Query: 588 GPTRDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 639 G DE A PG P P G G+ P PG P P GP G A+ P Sbjct: 1180 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239 Query: 640 ETPGPSPAGPTRDEPAKAGEA 660 PG + E + GEA Sbjct: 1240 GPPGSVGSVGGVGEKGEPGEA 1260 Score = 69.7 bits (169), Expect = 8e-12 Identities = 121/422 (28%), Positives = 150/422 (35%), Gaps = 80/422 (18%) Query: 310 VEEEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLER--- 360 + E G PG P QG G E +KG D GPQ S + AG P ER Sbjct: 981 IGERGHPGPPGPPGE-QGLPGAAGKEGAKG----DPGPQGISGKDGPAGLRGFPGERGLP 1035 Query: 361 -SQGDEAGGHGEDRPEPLSPKESKKRK--------LELSRREQPPTEPGPQSASEVEKIA 411 +QG GE P P S + + L R P PGP EK A Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG----EKGA 1091 Query: 412 LNLEGCALSQGSLRTGTQ-EVGGQDP-GEAVQPCRQPLGARVADKVRKRRKVDEGA---- 465 +G G R G Q VG P G A P + + +K K D+G Sbjct: 1092 PGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1149 Query: 466 GDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPS 519 G GA +A G P P G + G +E G GP +G PG P Sbjct: 1150 GPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207 Query: 520 ETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESP 578 E GP G P PGPR GP G A+ P PG G G++ Sbjct: 1208 EKGENGDVGPMG------PPGPPGPR--GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1259 Query: 579 SETPGP-------SPAGPTRDEPAESPSETPGPRPA-GPAGDE-PAESPSETPGPRPAGP 629 + PGP P G ++ P GP A GP GD+ P +P P GP Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1319 Query: 630 AGDEPAESPSETPG-----------PSPAGPTRD-----EPAKAGE--AAELQDAEVESS 671 G EP + + G P P GP+ + P K G AA + + E Sbjct: 1320 PG-EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1378 Query: 672 AK 673 AK Sbjct: 1379 AK 1380 Score = 69.3 bits (168), Expect = 1e-11 Identities = 98/359 (27%), Positives = 120/359 (33%), Gaps = 77/359 (21%) Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQS-ASEVEKIAL-NLEG 416 +R + + G GED PE PK R P +PGP A E K+ + L G Sbjct: 797 DRGEVGQIGPRGEDGPE--GPKG----------RAGPTGDPGPSGQAGEKGKLGVPGLPG 844 Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472 QG + G G+ V P G R R R G Sbjct: 845 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904 Query: 473 SGGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGP--KEGTPGSPSET------- 521 + G G P P G P+ G +G GP K+G PG P + Sbjct: 905 TSGGD-----GPPGPPGERGPQGPQGPVGFP-GPKGPPGPPGKDGLPGHPGQRGETGFQG 958 Query: 522 ----PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPA------ESPSETPGPRPA 567 PGP P GP G+ PGP GP G++ E PGP+ Sbjct: 959 KTGPPGPGGVVGPQGPTGETGPIGERGHPGP--PGPPGEQGLPGAAGKEGAKGDPGPQGI 1016 Query: 568 ----GPAGDE--PAE--------SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613 GPAG P E +P G P GP P SP E AGP G Sbjct: 1017 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGPIGLP 1074 Query: 614 PAESPSETPGPR----------PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662 P PGP P GPAG + + P PGP+ + E GE E Sbjct: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133 Score = 68.2 bits (165), Expect = 2e-11 Identities = 113/424 (26%), Positives = 145/424 (34%), Gaps = 65/424 (15%) Query: 288 PQDKLRRFK--PSSLPHPL--EGSRKVEEEGSPGDPDHEASTQGR-----TCGPEHSKGG 338 P DK R + P P P +G R + E P EA +G T G G Sbjct: 609 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668 Query: 339 GRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPK-----ESKKRKLELSRR 392 VD P P+ P Q G G P+ P+ P + K L Sbjct: 669 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 728 Query: 393 EQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLGARV 451 + PP PG + S EK AL G QG + G + V G D ++ + G Sbjct: 729 DGPPGHPGKEGQSG-EKGALGPPG---PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784 Query: 452 ADKVRKRRKVDEGAGDSAAVASGGAQ-------TLALAGSPAPSGHPKAGHSEN-GVE-- 501 + + G+ + G G P PSG +AG GV Sbjct: 785 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG--QAGEKGKLGVPGL 842 Query: 502 EDTEGRTGPKEGT--PGSPSET-----------PGP----SPAGPAGDEPAESPSETPGP 544 GR GPK T PG P PGP P GP G A P+ PGP Sbjct: 843 PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 902 Query: 545 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSE 600 + GD P P E P GP G + P PG P G + + + Sbjct: 903 KGTS-GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961 Query: 601 TPGP----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPT-R 651 PGP P GP G+ PG P GP G++ + G P P G + + Sbjct: 962 PPGPGGVVGPQGPTGETGPIGERGHPG--PPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019 Query: 652 DEPA 655 D PA Sbjct: 1020 DGPA 1023 Score = 66.6 bits (161), Expect = 7e-11 Identities = 100/367 (27%), Positives = 128/367 (34%), Gaps = 56/367 (15%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373 GSPG+ D + G G + SKG + P P ++ P AGG GE Sbjct: 1120 GSPGE-DGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP------GIAGGDGE-- 1169 Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433 P P + +K + R P PGP + L+G G + +VG Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGP-PGP----------IGLQGLPGPPGE-KGENGDVGP 1217 Query: 434 QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGH--- 490 P P R P G AD + G V G AG+P P G Sbjct: 1218 MGPPGPPGP-RGPQGPNGADGPQGP---PGSVGSVGGVGEKGEP--GEAGNPGPPGEAGV 1271 Query: 491 --PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP 546 PK E G E G GP +G PG P P G GD P P P Sbjct: 1272 GGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-----PGPPGEPGP 1325 Query: 547 AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE--SPSETPG 603 AG G + PG P P GP+G+ P GP A E + E Sbjct: 1326 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1385 Query: 604 PRPAGPAGDEPAESPSETPGPRP----AGPAGDE--PAESPSETPGPSPAGP-----TRD 652 P G G + P+ PGP GP G++ P + + P P P GP + Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKG 1444 Query: 653 EPAKAGE 659 +P GE Sbjct: 1445 DPGSKGE 1451 Score = 65.5 bits (158), Expect = 2e-10 Identities = 61/211 (28%), Positives = 77/211 (36%), Gaps = 28/211 (13%) Query: 479 LALAGSPAPSGHPKA----GHSENGVEEDTEGRTGP--------KEGTPGSPSETPGPSP 526 + L G P P G P + G S + + G GP K G PG+ P Sbjct: 534 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 593 Query: 527 AGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRPA-GPAGDEPA 575 G GD + PG + P GP GD+ GPR G AG Sbjct: 594 PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 653 Query: 576 ESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR-PAGPAGD 632 P TPG P G + P GP+ GP G + P PGP+ P GP G+ Sbjct: 654 LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 713 Query: 633 E-PAESPSETPGPSPAGPTRDEPAKAGEAAE 662 + P P P GP P K G++ E Sbjct: 714 KGPQGKPGLAGLPGADGPP-GHPGKEGQSGE 743 Score = 65.1 bits (157), Expect = 2e-10 Identities = 114/439 (25%), Positives = 145/439 (33%), Gaps = 105/439 (23%) Query: 312 EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371 E G PG P + GP + G D P PR + +GDE Sbjct: 1145 ENGPPGPPGLQ--------GPVGAPGIAGGDGEPGPRGQQGMFG-----QKGDEGARGFP 1191 Query: 372 DRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR 425 P P+ P K ++ PP PGP+ A +G S GS+ Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMG-PPGPPGPRGPQGPNG-ADGPQGPPGSVGSVG 1249 Query: 426 TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-------- 477 G E G +PGEA P P G + R AG A GA+ Sbjct: 1250 -GVGEKG--EPGEAGNP--GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1304 Query: 478 -----TLALAGSPAPSGHPKAGHSENGV-----EEDTEGRTGP-----KEGTPGSPSETP 522 + G P P G P ++GV E+ G+ GP + G PG P + Sbjct: 1305 KGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1363 Query: 523 GPSPAGPAG---------DEPAESPSETPGP-RPAGPAGDEPAESPSETPGP-------- 564 P AG G + AE P GP P GPAG E PGP Sbjct: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423 Query: 565 --------RPAGPAG------DEPAESPSETPG-------PSPAGPTRDEPAESPSETPG 603 P GP G D ++ PG P G D +PG Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483 Query: 604 -------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655 P PAGP G P PG P P GP G++ + P+ G S P Sbjct: 1484 AKGDGGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537 Query: 656 KAGEAAELQDAEVESSAKS 674 GE +Q + SS K+ Sbjct: 1538 PPGEV--IQPLPILSSKKT 1554 Score = 61.2 bits (147), Expect = 3e-09 Identities = 95/365 (26%), Positives = 121/365 (33%), Gaps = 81/365 (22%) Query: 287 GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346 GPQ P P + V E+G PG+ + GP G G GP+ Sbjct: 1228 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP--------GPPGEAGVG----GPK 1275 Query: 347 PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASE 406 E +AGP AG G P + + PP EPGP Sbjct: 1276 GERGEKGEAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ-- 1328 Query: 407 VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPC----RQPLGARVADKVRKRRKVD 462 +G +G Q GEA P R P GA A+ R+ + Sbjct: 1329 --------DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG----RQGE 1376 Query: 463 EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSE 520 +GA A A G G P+G P E G GP ++G PG+ + Sbjct: 1377 KGAKGEAG-AEGPPGKTGPVGPQGPAGKPGP--------EGLRGIPGPVGEQGLPGAAGQ 1427 Query: 521 TPGPSPAGPAG------DEPAESPSETPG-------PRPAGPAGDEPAESPSETPG---- 563 P P GP G D ++ PG P G GD +PG Sbjct: 1428 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1487 Query: 564 ---PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPS 619 P PAGP G P PG P P GP ++ + P AG GD P Sbjct: 1488 GGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGP--------AGQKGDSGLPGPP 1533 Query: 620 ETPGP 624 +PGP Sbjct: 1534 GSPGP 1538 Score = 50.8 bits (120), Expect = 4e-06 Identities = 52/184 (28%), Positives = 62/184 (33%), Gaps = 49/184 (26%) Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG--------- 563 G PG T P P G G A+ S PGP+ GP G + P+ PG Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ--GPRGVQGPPGPTGKPGKRGRPGADG 586 Query: 564 ----PRPAGPAGDEPAESPSETPG----------PSPAGPTRDE--------------PA 595 P G GD + PG P GP D+ P Sbjct: 587 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 646 Query: 596 ES-------PSETPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-S 645 E+ P TPG P G AG + P GP+ GP G + P PGP Sbjct: 647 EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706 Query: 646 PAGP 649 P GP Sbjct: 707 PIGP 710 Score = 45.1 bits (105), Expect = 2e-04 Identities = 56/192 (29%), Positives = 68/192 (35%), Gaps = 31/192 (16%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 G PA + + + +G + + P PG E P P PAGPAG P Sbjct: 404 GVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP-PGPAGPAG---IMGPPGLQ 459 Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES---PSETPGPSPAGPTRD-EPAESP 598 GP GP GD P PG A P P G GPT + A++ Sbjct: 460 GP--TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 517 Query: 599 SETPGPR-----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-------SP 646 + R P GP G T P P G G A+ S PGP P Sbjct: 518 AILQQARIALRGPPGPMG--------LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 569 Query: 647 AGPTRDEPAKAG 658 GPT +P K G Sbjct: 570 PGPT-GKPGKRG 580 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 79.7 bits (195), Expect = 8e-15 Identities = 90/328 (27%), Positives = 119/328 (36%), Gaps = 45/328 (13%) Query: 327 GRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRK 386 G GP S GG +GP P +PQ GP + G +P+ P+ K R Sbjct: 34 GNPQGP--SPQGGNKPQGPPPPPGKPQ--GPPPQGGNKPQGPPPPGKPQGPPPQGDKSR- 88 Query: 387 LELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR 444 S R P P P PQ ++ + G G + G GG P P + Sbjct: 89 ---SPRSPPGKPQGPPPQGGNQPQ-------GPPPPPGKPQ-GPPPQGGNRPQGPPPPGK 137 Query: 445 QPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDT 504 DK R R GG Q G P P G P+ + G Sbjct: 138 PQGPPPQGDKSRSPRSPP--GKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGG----- 187 Query: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 564 K P P + GP P G P + GP P G G++P + P PG Sbjct: 188 -----KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG--GNQP-QGPPPPPG- 238 Query: 565 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPG 623 +P GP P + ++ GP P G + PA+ S++ R P G P + + G Sbjct: 239 KPQGP----PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 294 Query: 624 PRPAGPAGDEPAESPSETPGPSPAGPTR 651 P P PAG P + P P P GP R Sbjct: 295 PPP--PAGGNP-QQPQAPPAGQPQGPPR 319 Score = 77.0 bits (188), Expect = 5e-14 Identities = 61/219 (27%), Positives = 83/219 (37%), Gaps = 24/219 (10%) Query: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521 D +S ++ +G Q + G P G P G + + G K P P + Sbjct: 22 DVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPP----GKPQGPPPQGGNKPQGPPPPGKP 77 Query: 522 PGPSPAGPAGDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESP 578 GP P G P P + GP P G P G P P + GP P G + P Sbjct: 78 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNRPQGPPPP 135 Query: 579 SETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 638 + GP P G P P + GP P G G++P + P PG +P GP P + Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQP-QGPPPPPG-KPQGP----PPQGG 187 Query: 639 SETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 + GP P G + P + D S + GKP Sbjct: 188 KKPQGPPPPGKPQGPPPQG-------DKSRSSQSPPGKP 219 Score = 76.6 bits (187), Expect = 7e-14 Identities = 60/215 (27%), Positives = 75/215 (34%), Gaps = 26/215 (12%) Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP------- 534 P P G P+ + G +G P G+ + P P P P G P Sbjct: 71 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ 130 Query: 535 -AESPSETPGPRPAGPAGDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPSPAGPT 590 P + GP P G P P + GP P G P G P P + GP P G Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGK 188 Query: 591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPSPA 647 + + P + GP P G P + GP P G P G P P + GP P Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQ 246 Query: 648 G---PTRDEPAKAGEAAELQDAEVESSAKS--GKP 677 G P P + Q SA+S GKP Sbjct: 247 GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281 Score = 71.6 bits (174), Expect = 2e-12 Identities = 55/201 (27%), Positives = 72/201 (35%), Gaps = 20/201 (9%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 G P P G P+ + G GP PG P GP P G P P + Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQ-----GPPP--PGKPQ---GPPPQGDKSRSPRSPPGKPQ 159 Query: 543 GPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPS 599 GP P G P G P P + GP P G + P + GP P G P Sbjct: 160 GPPPQGGNQPQGPPPP--PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217 Query: 600 ETPGPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAK 656 + GP P G P G P P + GP P G + P + GP G ++ + A+ Sbjct: 218 KPQGPPPQGGNQPQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 275 Query: 657 AGEAAELQDAEVESSAKSGKP 677 + + E + G P Sbjct: 276 SPPGKPQGPPQQEGNNPQGPP 296 Score = 58.2 bits (139), Expect = 3e-08 Identities = 72/291 (24%), Positives = 98/291 (33%), Gaps = 36/291 (12%) Query: 303 PLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--------GGRVDEGPQPRSVEPQD 354 P +G K + PG P ++ P G GG +GP P +PQ Sbjct: 61 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120 Query: 355 AGPL--ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKI 410 P R QG G +P+ P+ K R S R P P P PQ ++ + Sbjct: 121 PPPQGGNRPQGPPPPG----KPQGPPPQGDKSR----SPRSPPGKPQGPPPQGGNQPQ-- 170 Query: 411 ALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAA 470 G G + G GG+ P P + DK R + Sbjct: 171 -----GPPPPPGKPQ-GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP--GKPQGP 222 Query: 471 VASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPA 527 GG Q G P P G P+ + G + G +G P GS S++ P Sbjct: 223 PPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279 Query: 528 GPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 578 P G E + P PAG +P P+ P P P G P+ P Sbjct: 280 KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 78.6 bits (192), Expect = 2e-14 Identities = 115/389 (29%), Positives = 143/389 (36%), Gaps = 67/389 (17%) Query: 300 LPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLE 359 LP P+ EG PG P S R GP + G + P P+ P AG Sbjct: 1064 LPGPVGALGLKGNEGPPGPPGPAGSPGER--GPAGAAGPIGIPGRPGPQG-PPGPAG--- 1117 Query: 360 RSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCAL 419 E G GE P+ + ++ + + L P PG +K + G Sbjct: 1118 -----EKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG----DKGEIGEPGQKG 1168 Query: 420 SQGSLRTGTQEVGGQDPGEAVQPCRQP--LGARVADKVRKRRKVDEGAGDSAAVASGGAQ 477 S+G E G P P QP GA R ++ + GD G Sbjct: 1169 SKGD----KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP 1224 Query: 478 -TLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPG--SPSETPGPS-PAGPAGD- 532 + L G P P G E G D G+ GP G PG PS PG P GP G Sbjct: 1225 GPVGLQGLPGPPG-------EKGETGDV-GQMGPP-GPPGPRGPSGAPGADGPQGPPGGI 1275 Query: 533 ----------EPAES-----PSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDE-PA 575 EP E+ P E P P G G++ PS GP P GP GD+ P Sbjct: 1276 GNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK 1335 Query: 576 ESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAE-SPSETPGPRPAGPAGDE 633 SP P GP P E PGP GP GD+ + P +T P P G G Sbjct: 1336 GSPGPVGFPGDPGP----PGE-----PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPG-- 1384 Query: 634 PAESPSETPGPSPAGP--TRDEPAKAGEA 660 P+ P + P PAGP + E GEA Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEA 1413 Score = 78.2 bits (191), Expect = 2e-14 Identities = 119/435 (27%), Positives = 148/435 (34%), Gaps = 73/435 (16%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKG-----GGRVDEGPQPRS 349 P+ P P ++G PG P T QG+T GP G G + GP Sbjct: 956 PTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT-GPPGPPGVVGPQGPTGETGPMGER 1014 Query: 350 VEPQDAGP-----------LERSQGDE--AGGHGEDRPEPLSPKESKKR------KLELS 390 P GP E ++GD AG G+D P L + L L Sbjct: 1015 GHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLK 1074 Query: 391 RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450 E PP PGP + S E+ G G R G Q G + + P G Sbjct: 1075 GNEGPPGPPGP-AGSPGERGPAGAAGPIGIPG--RPGPQGPPGPAGEKGAPGEKGPQGPA 1131 Query: 451 VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510 D ++ + AG G + G P G K E G G TGP Sbjct: 1132 GRDGLQGPVGLPGPAGPVGPPGEDGDK--GEIGEPGQKGS-KGDKGEQG----PPGPTGP 1184 Query: 511 KE--GTPGSPSETPGPSPAGPAG---DEPAESPSETPGPR-------------PAGPAGD 552 + G PG P P G G + E P PGP G GD Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244 Query: 553 EPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAES-----PSETPG 603 P PGPR GP+G A+ P PG P G + EP E+ P E Sbjct: 1245 VGQMGPPGPPGPR--GPSGAPGADGPQGPPGGIGNPGAVGE-KGEPGEAGEPGLPGEGGP 1301 Query: 604 PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662 P P G G++ PS GP P GP GD+ P +PGP P + G A Sbjct: 1302 PGPKGERGEKGESGPSGAAGPPGPKGPPGDD---GPKGSPGPVGFPGDPGPPGEPGPAG- 1357 Query: 663 LQDAEVESSAKSGKP 677 QD G+P Sbjct: 1358 -QDGPPGDKGDDGEP 1371 Score = 71.6 bits (174), Expect = 2e-12 Identities = 102/361 (28%), Positives = 127/361 (35%), Gaps = 59/361 (16%) Query: 338 GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPT 397 G R + GP E GP R GG D P PL P +K KL + P Sbjct: 826 GDRGEIGPPGPRGEDGPEGPKGR------GGPNGD-PGPLGPP-GEKGKLGVPGLPGYPG 877 Query: 398 EPGPQSASEVEKIALNLEGCALSQGSLRT-GTQEVGGQDPGEAVQPCRQPLGARVADKVR 456 GP+ + G +G T G GQ + R P G + Sbjct: 878 RQGPKGSIGFP----GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK 933 Query: 457 KRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKA-------GHSENGVEEDTEGRTG 509 D AG G Q G P P G P GH E +G+TG Sbjct: 934 GNSGGDGPAGPPGERGPNGPQ--GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991 Query: 510 PKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPG-- 563 P G PG GP G+ P PG P AG G + P+ PG Sbjct: 992 PP-GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKD 1050 Query: 564 --------------PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET-----PGP 604 P P G G + E P PGP+ P PA + PGP Sbjct: 1051 GPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA-GSPGERGPAGAAGPIGIPGRPGP 1109 Query: 605 R-PAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPS-PAGPTRDEPAKAGEAA 661 + P GPAG++ A PG + P GPAG + + P PGP+ P GP ++ K GE Sbjct: 1110 QGPPGPAGEKGA------PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDK-GEIG 1162 Query: 662 E 662 E Sbjct: 1163 E 1163 Score = 67.8 bits (164), Expect = 3e-11 Identities = 103/369 (27%), Positives = 129/369 (34%), Gaps = 45/369 (12%) Query: 313 EGSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHG 370 +G PG P QG GP +G G + GPQ P + GPL + G G Sbjct: 702 DGQPG-PKGNVGPQGEP-GPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKP--GLPGMPG 757 Query: 371 EDRPEPLSPKES---KKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-- 425 D P KE +K + P PGP+ + I L+G +G Sbjct: 758 ADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIR-GLKGTKGEKGEDGFP 816 Query: 426 --TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALA 482 G + G D GE P G R D + GD + G + L + Sbjct: 817 GFKGDMGIKG-DRGEIGPP-----GPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVP 870 Query: 483 GSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESP 538 G P G PK G G G K GTPG P P GP G+ Sbjct: 871 GLPGYPGRQGPKGSIGFPGFP----GANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI 926 Query: 539 SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTR 591 + PGP+ GD PA P E P GP G + P PG P G T Sbjct: 927 TGKPGPK-GNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG 985 Query: 592 DEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSP 646 + P PG P GP G+ PG P GP G++ + G P P Sbjct: 986 FQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG--PPGPPGEQGLPGLAGKEGTKGDPGP 1043 Query: 647 AG-PTRDEP 654 AG P +D P Sbjct: 1044 AGLPGKDGP 1052 Score = 66.2 bits (160), Expect = 9e-11 Identities = 63/218 (28%), Positives = 79/218 (36%), Gaps = 32/218 (14%) Query: 474 GGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPG-------- 523 G A + L G P P G P +G + E G GP+ +G PG P+ PG Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKG--EPGDVGPQGPRGVQGPPG-PAGKPGRRGRAGSD 615 Query: 524 -----PSPAGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRP-A 567 P GP GD + + PG + P GP GD+ GPR Sbjct: 616 GARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLP 675 Query: 568 GPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR 625 G G P PG P P G T + P GP+ GP G + PGP+ Sbjct: 676 GEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQ 735 Query: 626 PA-GPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662 A GP G++ PG A P K G E Sbjct: 736 GAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773 Score = 65.1 bits (157), Expect = 2e-10 Identities = 106/438 (24%), Positives = 143/438 (32%), Gaps = 97/438 (22%) Query: 312 EEGSPGDPDHEASTQGRTC--GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGH 369 ++GS GD E G T GP G D P PR + L +GDE Sbjct: 1166 QKGSKGDKG-EQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQG-----LFGQKGDEGPRG 1219 Query: 370 GEDRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGS 423 P P+ P K ++ + PP PGP+ S A +G G Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMG-PPGPPGPRGPSG----APGADGPQGPPGG 1274 Query: 424 LRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS---------- 473 + +PGEA +P G K + K + G +A Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334 Query: 474 -GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS------ 525 G + G P P G P AG ++ +G G + G+PG P+ PGPS Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG-QTGSPG-PTGEPGPSGPPGKR 1392 Query: 526 -PAGPAGDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG----PRPAGPAGDE 573 P GPAG E + G P GP G + A G P P G G Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLP 1452 Query: 574 PAESPSETPGPSPA-------------------------GPTRDEPAESPSETPGPR-PA 607 + P PGP GP ++ + PGP+ + Sbjct: 1453 GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512 Query: 608 GPAGDEPAESPSET------------PGPR-------PAGPAGDEPAESPSETPGPSPAG 648 GP G++ PS PGP+ P GP G+ P PGP P Sbjct: 1513 GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP-PGE 1571 Query: 649 PTRDEPAKAGEAAELQDA 666 + P +A DA Sbjct: 1572 VIQPLPIQASRTRRNIDA 1589 Score = 62.4 bits (150), Expect = 1e-09 Identities = 89/326 (27%), Positives = 110/326 (33%), Gaps = 56/326 (17%) Query: 313 EGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE- 371 +G PG P R G GG +GP + E Q L++++ G G Sbjct: 510 DGLPGPPGTMLMLPFRFGG-----GGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPM 564 Query: 372 ---DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGT 428 RP P+ P S K E P + GPQ G Sbjct: 565 GLTGRPGPVGPPGSGGLKGE-------PGDVGPQ------------------------GP 593 Query: 429 QEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALAGSPAP 487 + V G PG A +P R+ G +D R GD G G P P Sbjct: 594 RGVQGP-PGPAGKPGRR--GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650 Query: 488 SGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETP--GP-SPAGPAGDEPAESPSETPGP 544 SG P G + E +G GP+ G PG P GP P GP G PGP Sbjct: 651 SGPP--GPPGDDGERGDDGEVGPR-GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGP 707 Query: 545 R-PAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPS 599 + GP G+ PG P P G G + P PG P P D P P Sbjct: 708 KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPG-LPGMPGADGPPGHPG 766 Query: 600 ETPGPRPAGPAGDEPAESPSETPGPR 625 + P G G + P PGPR Sbjct: 767 KEGPPGEKGGQGPPGPQGPIGYPGPR 792 Score = 51.2 bits (121), Expect = 3e-06 Identities = 54/204 (26%), Positives = 68/204 (33%), Gaps = 37/204 (18%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 G A S P E+ + + G G T P P GP G + Sbjct: 529 GGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDV 588 Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETP 602 GP+ GP G + P+ PG R G AG + A P GP D + + P Sbjct: 589 GPQ--GPRGVQGPPGPAGKPGRR--GRAGSDGARGM-----PGQTGPKGDRGFDGLAGLP 639 Query: 603 GPR----------PAGPAGDE----------PAESPSETPGPR-------PAGPAGDEPA 635 G + P GP GD+ P P E PGPR P GP G Sbjct: 640 GEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGE-PGPRGLLGPKGPPGPPGPPGV 698 Query: 636 ESPSETPGPSPAGPTRDEPAKAGE 659 PGP + EP G+ Sbjct: 699 TGMDGQPGPKGNVGPQGEPGPPGQ 722 Score = 48.9 bits (115), Expect = 2e-05 Identities = 59/217 (27%), Positives = 73/217 (33%), Gaps = 50/217 (23%) Query: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------PRPAGP-------- 549 EG GP EG G P P G GD P PG P P G Sbjct: 468 EGPPGP-EGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRF 526 Query: 550 --AGDEPAESPSETPGPRPA------------GPAGDEPAESPSETPGPSPAGPTRDEPA 595 GD ++ P + A GPAG GP +G + EP Sbjct: 527 GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPG 586 Query: 596 ESPSETPGPR----PAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPG---- 643 + + GPR P GPAG + + G P GP GD + + PG Sbjct: 587 DVGPQ--GPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH 644 Query: 644 ---PSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 P P+GP P GE + D EV G+P Sbjct: 645 RGDPGPSGPP-GPPGDDGERGD--DGEVGPRGLPGEP 678 Score = 42.0 bits (97), Expect = 0.002 Identities = 54/215 (25%), Positives = 67/215 (31%), Gaps = 25/215 (11%) Query: 460 KVDEGAGDSAAVASGGAQTLALAG--SPAPSGHPKAGHSENGVEEDTEGRTG---PKEGT 514 + EGAG V G + +P+P G E ++ T+ G P Sbjct: 322 ETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTA 381 Query: 515 PGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEP 574 S S P P P A D E ET DE P P P+ P Sbjct: 382 DTSNSSNPAPPPGEGADDLEGEFTEETIRNL------DENYYDPYYDPTSSPSEIGPGMP 435 Query: 575 AESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----RPAGPA 630 A + G + + E PG GP G E P+ PGP P G Sbjct: 436 ANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPG---PEGPAGLPGPPGTMGPTGQV 492 Query: 631 GDEPAESPSETPG-------PSPAGPTRDEPAKAG 658 GD P PG P P G P + G Sbjct: 493 GDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527 Score = 31.6 bits (70), Expect = 2.5 Identities = 39/154 (25%), Positives = 50/154 (32%), Gaps = 5/154 (3%) Query: 490 HPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGP 549 +P ++E E +T P P + P PS E A+ +E P P Sbjct: 258 NPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPV---EAAKETTEVPEELTPTP 314 Query: 550 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP-TRDEPAESPSETPGPRPAG 608 P SE G GD + PSP T E E+P + P Sbjct: 315 TEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGA 374 Query: 609 PAGDEPAE-SPSETPGPRPAGPAGDEPAESPSET 641 A+ S S P P P A D E ET Sbjct: 375 EIPTSTADTSNSSNPAPPPGEGADDLEGEFTEET 408 >gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-chain family member 2 [Homo sapiens] Length = 1122 Score = 78.6 bits (192), Expect = 2e-14 Identities = 64/186 (34%), Positives = 94/186 (50%), Gaps = 22/186 (11%) Query: 487 PSGHPKAGHSENGVEEDTEGRTGPKEG----TPGSPSETPGPSPAGPAGDEPAESPSE-T 541 PS P A + E G P TP TP P A P+ D+ ++P+E Sbjct: 360 PSAPPSADDNIKTTAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAEHL 419 Query: 542 PGPRPAGPAGDEPAESPSE---TPGPRPAGPAGDEPAESPSE-TPGPSPAGPTRDEPAES 597 GP P P+ D+ ++PSE TP P A P+ D+ ++P+E GP P P+ D+ ++ Sbjct: 420 RGPLP--PSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLP--PSADDNLKT 475 Query: 598 PSE---TPGPRPAGPAGDEPAESPSE-TPGPRPAGPAGDEPAESPSE---TPGPSPAGPT 650 PSE TP P A P+ D+ ++P+E GP P P+ D+ ++PSE TP P A P+ Sbjct: 476 PSERQLTPLPPSAPPSADDNIKTPAEHLRGPLP--PSADDNLKTPSERQLTPLPPSAPPS 533 Query: 651 RDEPAK 656 D+ K Sbjct: 534 ADDNIK 539 Score = 67.8 bits (164), Expect = 3e-11 Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 19/177 (10%) Query: 514 TPGSPSETPGPSPAGPAGDEPAESPSE-TPGPRPAGPAGDEPAESPSE---TPGPRPAGP 569 TP TP P A P+ D+ ++P+E GP P P+ D+ ++PSE TP P A P Sbjct: 902 TPSKRQLTPLPPSAPPSADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPP 959 Query: 570 AGDEPAESPSE-TPGPSPAGPTRDEPAESPSE---TPGPRPAGPAGDEPAESPSE-TPGP 624 + D+ ++P+E GP P P+ D+ ++PSE TP P A + D+ ++P+E GP Sbjct: 960 SADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPTSADDNIKTPAERLRGP 1017 Query: 625 RPAGPAGDEPAESP----SETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 P P+ D+ ++P E P P R A+ E + V S KP Sbjct: 1018 LP--PSADDNLKTPPLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKP 1072 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 77.4 bits (189), Expect = 4e-14 Identities = 59/188 (31%), Positives = 80/188 (42%), Gaps = 15/188 (7%) Query: 497 ENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR------PAGPA 550 E G EE+ EG + P + +P P +E A+SP+E P PA Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEE-AKSPAEAKSPEKEEAKSPAEVK 545 Query: 551 GDEPAESPS--ETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAG 608 E A+SP+ E P A E A+SP+E P A E A+SP+E P A Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605 Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668 E A+SP+E P E A+SP+E P A E AK+ E A+ + E Sbjct: 606 SPVKEEAKSPAEAKSP------VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEE 659 Query: 669 ESSAKSGK 676 S + K Sbjct: 660 AKSPEKAK 667 Score = 73.2 bits (178), Expect = 8e-13 Identities = 76/308 (24%), Positives = 116/308 (37%), Gaps = 34/308 (11%) Query: 381 ESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAV 440 E K + +E S +E E + E++ E + G +E GG++ Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE----KEAKEEEGKEEEGGEEEE--- 493 Query: 441 QPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGV 500 A ++ K +E A S + A SPA + P+ +++ Sbjct: 494 --------AEGGEEETKSPPAEEAASPEKEAKSPVKEE---AKSPAEAKSPEKEEAKSPA 542 Query: 501 EEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE 560 E + P++ + E P A E A+SP+E P A E A+SP+E Sbjct: 543 EVKS-----PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597 Query: 561 TPGPRPAGPAGDEPAESPSETPGP------SPAGPTRDEPAESPS--ETPGPRPAGPAGD 612 P A E A+SP+E P SPA E A+SP+ E P A Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657 Query: 613 EPAESPSETPGPRPAGPAGDEPAESPSETPGPSP---AGPTRDEPAKAGEAAELQDAEVE 669 E A+SP + P A E A+SP + SP P ++E +A E + Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717 Query: 670 SSAKSGKP 677 S K+ P Sbjct: 718 SPEKAKSP 725 Score = 63.9 bits (154), Expect = 5e-10 Identities = 73/300 (24%), Positives = 115/300 (38%), Gaps = 12/300 (4%) Query: 375 EPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQ 434 E ++ +E K+ K E + E+ E + E K + E A + ++ +E + Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK-SPPAEEAASPEKEAKSPVKEEA-K 525 Query: 435 DPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSA-AVASGGAQTLALAGSPAPSGHPKA 493 P EA P ++ A+ +V+ K A + A + + A SPA P+ Sbjct: 526 SPAEAKSPEKEE--AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583 Query: 494 GHSENGVEEDTEGRT-GPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGD 552 S E + P++ E P+ A E A+SP+E P A Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643 Query: 553 EPAESPSETPGPRPAGPAGDEPAESPSETPGPSP---AGPTRDEPAESPSETPGPRPAGP 609 E A+SP + P E A+SP + SP P + E A+SP + P Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE-AKSPEKAKSPVKEEA 702 Query: 610 AGDEPAESP--SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAE 667 E A+SP E P A E A++P + P E AK+ E A+ D + Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762 Score = 62.8 bits (151), Expect = 1e-09 Identities = 87/377 (23%), Positives = 134/377 (35%), Gaps = 28/377 (7%) Query: 311 EEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHG 370 EEEG + E +G G E +K + S E + P++ A Sbjct: 480 EEEGKEEEGGEEEEAEG---GEEETKS----PPAEEAASPEKEAKSPVKEEAKSPAEAKS 532 Query: 371 EDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQE 430 ++ E SP E K + S ++ P + E E+ E S ++ +E Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE--VKSPEKAKSPAKE 590 Query: 431 VGGQDPGEAVQP--CRQPLGARVADKVRKRRKVDEGAGDSAAVAS---GGAQTLALAGSP 485 + P EA P + P+ + V E A A V S + T A SP Sbjct: 591 EA-KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649 Query: 486 APSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESP--SETPG 543 KA E + E P + SP + P A E A+SP E Sbjct: 650 E-----KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704 Query: 544 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603 P A E A+SP + P E A+SP + SP E A++ + Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT-LDVKS 763 Query: 604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP---SPAGPTRDEPAKAGEA 660 P PA +E A SP++ + P +E +SP + P P ++ P K Sbjct: 764 PEAKTPAKEE-ARSPADKFPEKAKSPVKEE-VKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821 Query: 661 AELQDAEVESSAKSGKP 677 + +++ E K +P Sbjct: 822 SPVKEEEKPQEVKVKEP 838 Score = 59.3 bits (142), Expect = 1e-08 Identities = 75/330 (22%), Positives = 126/330 (38%), Gaps = 34/330 (10%) Query: 346 QPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSAS 405 + + + ++ E + +EA G E+ P + + + K S ++ P + Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533 Query: 406 EVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGA 465 E E+ E S ++ +E + P EA P ++ A+ +V+ K A Sbjct: 534 EKEEAKSPAE--VKSPEKAKSPAKEEA-KSPPEAKSPEKEE--AKSPAEVKSPEKAKSPA 588 Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS 525 + A + A++ A SP +++ V+E+ + SP+E P Sbjct: 589 KEEAK-SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK-----------SPAEVKSPE 636 Query: 526 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPS 585 A E A+SP + P E A+SP + P A E A+SP + S Sbjct: 637 KAKSPTKEEAKSPEKAKSPE------KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690 Query: 586 PAGPTRDEPAESP--SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 643 P E A+SP E P A E A+SP + P E A+SP + Sbjct: 691 P------EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744 Query: 644 PSPAGPTRDEPAKAGEAAELQDAEVESSAK 673 SP E AK +++ E ++ AK Sbjct: 745 KSPEKAKSPEKAK---TLDVKSPEAKTPAK 771 Score = 50.4 bits (119), Expect = 5e-06 Identities = 80/385 (20%), Positives = 144/385 (37%), Gaps = 36/385 (9%) Query: 307 SRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA 366 ++ E+ SP + ++ + ++ E +K V + +S ++A E+++ E Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE- 656 Query: 367 GGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRT 426 + E SP+++K ++ + P A EK ++ A S ++ Sbjct: 657 ------KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710 Query: 427 GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPA 486 +E + P +A P ++ A+ +K + K +E A + A+TL + A Sbjct: 711 PVKEEA-KSPEKAKSPVKEE--AKTPEKAKSPVK-EEAKSPEKAKSPEKAKTLDVKSPEA 766 Query: 487 PSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGP---SPAGPAGDEPAESPSETPG 543 + P + + ++ E P + SP + P P + P + ++P Sbjct: 767 KT--PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824 Query: 544 PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETP----GPSPAGPTRDEPA-ES 597 P + E P + + PA P +E +S E P P + EPA E Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884 Query: 598 PSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP-----SETPGPSPAGPTRD 652 P E+ A E AE + P P PA E E +E P Sbjct: 885 PKESKVE-----AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAK 939 Query: 653 EPAKAGE----AAELQDAEVESSAK 673 EP+K E A E +D + E + K Sbjct: 940 EPSKPAEKKEAAPEKKDTKEEKAKK 964 Score = 38.5 bits (88), Expect = 0.021 Identities = 45/177 (25%), Positives = 64/177 (36%), Gaps = 20/177 (11%) Query: 491 PKAGHSENGVEEDTEGRTGPK---EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA 547 PK ++ +E+ + PK E E P S A E AE + P P Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV-EAKKEEAEDKKKVPTPEKE 909 Query: 548 GPAGDEPAES--PSETPGPRPAGPAGDEPAESPSETPGPSPAGP----TRDEPAESPSET 601 PA E E P E P D A+ PS+ A P T++E A+ P E Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEP-DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968 Query: 602 PGPRPAGPAGDEPAESPSETPGPRPAGPAGD--EPAESPSETPGPSPAGPTRDEPAK 656 P + A+ +T P+ P + E + S + P T D+ AK Sbjct: 969 -------PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018 Score = 37.7 bits (86), Expect = 0.035 Identities = 78/384 (20%), Positives = 134/384 (34%), Gaps = 43/384 (11%) Query: 305 EGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDA-GPLERSQG 363 E ++ E+ SP + ++ + ++ +K + + + P+ A P++ Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703 Query: 364 DEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGS 423 + E SP+++K E ++ + P + A EK + L S Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763 Query: 424 --LRTGTQEVGGQDPGEAVQPCRQPLGARVA--DKVRKRRKVDEGAGD----------SA 469 +T +E + + + P+ V +K + K D A + S Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823 Query: 470 AVASGGAQTLALAGSPAPSGHPKAGHSENGVEE-DTEGRTGPKEGTPGSPSETPGPSPAG 528 Q + + P + KA + E+ D++ PK+ P E Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE----EKKE 879 Query: 529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPSP 586 PA ++P ES E A E AE + P P PA E E P E + Sbjct: 880 PAVEKPKESKVE---------AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK 930 Query: 587 AGPTRDEPAESPSETPGPRPAGP----AGDEPAESPSETPGPRPAGPAGD-----EPAES 637 P D A+ PS+ + A P +E A+ P E P D EP++ Sbjct: 931 KEPD-DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989 Query: 638 PSETPGPSPAGPTRDE--PAKAGE 659 +E S + +D P KA E Sbjct: 990 KAEKAEKSSSTDQKDSKPPEKATE 1013 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 76.6 bits (187), Expect = 7e-14 Identities = 110/410 (26%), Positives = 132/410 (32%), Gaps = 73/410 (17%) Query: 299 SLPHPLEGSRKVEEEGSPGDPDHEASTQGR------TCGPEHSKGGGRVD--EGPQPRSV 350 SL L S +P P+ A+ G + P + G G EG + Sbjct: 28 SLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP 87 Query: 351 EPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKI 410 EP AG GG G RP P SP RR P P P +A K+ Sbjct: 88 EPPPAGRAR------PGGGGPQRPGPPSP-----------RRPLVPAGPAPPAA----KL 126 Query: 411 ALNLEGCALSQGSLRTGTQEVGGQDP---GEAVQPCRQPLGARVADKVRKRRKVDEGAGD 467 EG A S + G +P G A L AR G G Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186 Query: 468 SAAVASGGAQTLALAGSPAPSGH---PKAGHSENG----------VEEDTEGRTGPKEGT 514 G AQTL + + S H P NG T +T P G Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246 Query: 515 -----PGSPSETPGPSPAGPAGDEPAESPSET----PGPRPAGPAGDEPAESP------- 558 P +PS P+PA PA P P+ P PAGP PA P Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306 Query: 559 -----SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613 + P P GPAG S PG + A P AESP P PA Sbjct: 307 GSAGAAPAPAPAAGGPAG----VSGQPGPGAAAAAPAPGVKAESPKRVVQAAP--PAAQT 360 Query: 614 PAES-PSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662 A S P+ T GP SP+ P P+P PT AG + Sbjct: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQ 410 Score = 58.5 bits (140), Expect = 2e-08 Identities = 72/254 (28%), Positives = 86/254 (33%), Gaps = 43/254 (16%) Query: 432 GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491 G Q PG P R + A A K R EG+ S A A A+A P P+ Sbjct: 101 GPQRPGPP-SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAA---AVAAGPEPA--- 153 Query: 492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSP-AGPAGDEPAESPSETPGPRPAGPA 550 P P++ GP+ A AG P P PGP P PA Sbjct: 154 -----------------------PAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190 Query: 551 GDEPAE----SPSETPGPRPAGPAGDEPAESPSET-PGPSPAGP-TRDEPAESPSETPGP 604 G A+ S + A PA P+ P P PA P T + P Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250 Query: 605 RPAGP---AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAA 661 PA P A PA +P+ P P P PA A P GP A P PA A Sbjct: 251 APAAPSPPAAPAPA-APAAAPPPPPPAPA--TLARPPGHPAGPPTAAPAVPPPAAAQNGG 307 Query: 662 ELQDAEVESSAKSG 675 A + A G Sbjct: 308 SAGAAPAPAPAAGG 321 Score = 44.7 bits (104), Expect = 3e-04 Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 11/114 (9%) Query: 567 AGPAGDEPAE-SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP- 624 AG G+ SP+ G PA P P +P P R A P G P + PGP Sbjct: 55 AGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR-ARPGGGGP-----QRPGPP 108 Query: 625 ---RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675 RP PAG P + P AG PA A AA + A + +G Sbjct: 109 SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162 >gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] Length = 1028 Score = 76.6 bits (187), Expect = 7e-14 Identities = 63/187 (33%), Positives = 71/187 (37%), Gaps = 26/187 (13%) Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540 + G P P G P A G G K G PG+ E P +GP+GDE P E Sbjct: 354 IQGPPGPKGDPGAF-----------GLKGEK-GEPGADGEAGRPGSSGPSGDEG--QPGE 399 Query: 541 TPGPRPAGPAGDE----PAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE 596 P G AGDE P +P E GP GP G P PG AGP D+ E Sbjct: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGE--AGPQGDQGRE 457 Query: 597 SPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655 P PG P AGP G + PG G A P+ PG R E Sbjct: 458 GPVGVPGDPGEAGPIGPKGYRGDEGPPGSE-----GARGAPGPAGPPGDPGLMGERGEDG 512 Query: 656 KAGEAAE 662 AG E Sbjct: 513 PAGNGTE 519 Score = 63.9 bits (154), Expect = 5e-10 Identities = 100/355 (28%), Positives = 130/355 (36%), Gaps = 42/355 (11%) Query: 330 CGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLEL 389 C P G R D G + +P G + EAG G RP L P + K E Sbjct: 252 CQPARGPPGLRGDPGFEGERGKPGLPG-----EKGEAGDPG--RPGDLGPVGYQGMKGEK 304 Query: 390 SRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLG 448 R + + GP+ EK ++G +G + G G + +Q P G Sbjct: 305 GSRGEKGSR-GPKGYKG-EKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362 Query: 449 ARVADKVRKRRKVDEGAGDSAAV--ASGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTE 505 A + K K + GA A +SG + G P P G +AG N + Sbjct: 363 DPGAFGL-KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421 Query: 506 G-RTGPKE----GTPGSPSETPGPSPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 559 G R GP E GTPG+ P AGP GD+ E P PG P AGP G + Sbjct: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481 Query: 560 ETPG-------PRPAGPAGDEPAESPSETPGPSPAGP-----------TRDEPAESPSE- 600 PG P PAGP GD GP+ G R P + ++ Sbjct: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541 Query: 601 TPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPAGPTRDE 653 PG + G AGD P + ++ G G E P PG P GP E Sbjct: 542 YPGLKGDEGEAGD-PGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595 >gi|157074225 nuclear pore complex interacting protein-like 3 [Homo sapiens] Length = 678 Score = 76.3 bits (186), Expect = 9e-14 Identities = 57/155 (36%), Positives = 86/155 (55%), Gaps = 18/155 (11%) Query: 514 TPGSPSETPGPSPAGPAGDEPAESPSE-TPGPRPAGPAGDEPAESPSE---TPGPRPAGP 569 TP TP P A P+ D+ ++P+E GP P P+ D+ ++PSE TP P A P Sbjct: 387 TPSERQLTPLPPSAPPSADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPP 444 Query: 570 AGDEPAESPSE-TPGPSPAGPTRDEPAESPSE---TPGPRPAGPAGDEPAESPSE-TPGP 624 + D+ ++P+E GP P P+ D+ ++PSE TP P A P+ D+ ++P+E GP Sbjct: 445 SADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGP 502 Query: 625 RPAGPAGDEPAESPSE---TPGPSPAGPTRDEPAK 656 P P+ D+ ++PSE TP P A P+ D+ K Sbjct: 503 LP--PSADDNLKTPSERQLTPLPPSAPPSADDNIK 535 Score = 39.7 bits (91), Expect = 0.009 Identities = 47/196 (23%), Positives = 68/196 (34%), Gaps = 29/196 (14%) Query: 487 PSGHPKAGHSENGVEEDTEGRTGPKEG----TPGSPSETPGPSPAGPAGDEPAESPSE-T 541 PS P A + E G P TP TP P A P+ D+ ++P+E Sbjct: 482 PSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERL 541 Query: 542 PGPRPAGPAGDEPAESP----SETPGPRPAGPAGDEPAE-SPSETPGPSPAG-------P 589 GP P P+ D+ ++P E +P P AE P P G P Sbjct: 542 RGPLP--PSADDNLKTPPLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKP 599 Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESPS---------ETPGPRPAGPAGDEPAESPSE 640 R A+ +P P+ EP+ P +P P+ EP+ P Sbjct: 600 KRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKR 659 Query: 641 TPGPSPAGPTRDEPAK 656 + P+ EP + Sbjct: 660 RRA-ADVEPSLPEPKR 674 >gi|139394646 iroquois homeobox protein 5 [Homo sapiens] Length = 483 Score = 75.5 bits (184), Expect = 2e-13 Identities = 67/203 (33%), Positives = 85/203 (41%), Gaps = 20/203 (9%) Query: 463 EGAGDSAAVASGGAQTLALAGSPAPSGHPK-AGHSENGVEEDTEGRTGPKEGTPGS---P 518 E GD +GGA+ A +G G P AG G D++ + P EG + P Sbjct: 208 EDKGDPEGPEAGGAEQKAASGCERLQGPPTPAGKETEGSLSDSDFKEPPSEGRLDALQGP 267 Query: 519 SETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 578 T GPSPAGPA AE P+ P PAG PA P G P GP G SP Sbjct: 268 PRTGGPSPAGPAAARLAEDPA------PHYPAG-APAPGPHPAAGEVPPGPGGPSVIHSP 320 Query: 579 SETPGPSP-AGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP---RPAGPAGDEP 634 P P+ A P AE + + + G G+E + P PGP + G + P Sbjct: 321 PPPPPPAVLAKPKLWSLAEIATSSDKVKDGG-GGNEGSPCP-PCPGPIAGQALGGSRASP 378 Query: 635 AESPSETPG---PSPAGPTRDEP 654 A +PS +P P P G P Sbjct: 379 APAPSRSPSAQCPFPGGTVLSRP 401 Score = 55.8 bits (133), Expect = 1e-07 Identities = 44/129 (34%), Positives = 52/129 (40%), Gaps = 18/129 (13%) Query: 532 DEPA--ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589 DEP E + GP AG A + A GP PAG E S S++ P Sbjct: 202 DEPQKPEDKGDPEGPE-AGGAEQKAASGCERLQGPPT--PAGKETEGSLSDSDFKEPPSE 258 Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESP-------SETPGPRPA------GPAGDEPAE 636 R + + P T GP PAGPA AE P + PGP PA GP G Sbjct: 259 GRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPAAGEVPPGPGGPSVIH 318 Query: 637 SPSETPGPS 645 SP P P+ Sbjct: 319 SPPPPPPPA 327 Score = 42.7 bits (99), Expect = 0.001 Identities = 36/106 (33%), Positives = 44/106 (41%), Gaps = 14/106 (13%) Query: 552 DEPA--ESPSETPGPRPAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPGPRPAG 608 DEP E + GP AG A + A GP +PAG E S S++ P Sbjct: 202 DEPQKPEDKGDPEGPE-AGGAEQKAASGCERLQGPPTPAGK---ETEGSLSDSDFKEPPS 257 Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESP-------SETPGPSPA 647 + + P T GP PAGPA AE P + PGP PA Sbjct: 258 EGRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPA 303 Score = 37.0 bits (84), Expect = 0.060 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 5/80 (6%) Query: 572 DEPA--ESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGP 629 DEP E + GP AG + A GP PAG E S S++ P Sbjct: 202 DEPQKPEDKGDPEGPE-AGGAEQKAASGCERLQGPPT--PAGKETEGSLSDSDFKEPPSE 258 Query: 630 AGDEPAESPSETPGPSPAGP 649 + + P T GPSPAGP Sbjct: 259 GRLDALQGPPRTGGPSPAGP 278 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 74.7 bits (182), Expect = 3e-13 Identities = 78/261 (29%), Positives = 100/261 (38%), Gaps = 38/261 (14%) Query: 436 PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGH 495 P AV P +P A +E +AAV + T A P P Sbjct: 1029 PAAAVPPPEEPTSPAAAVPTP-----EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083 Query: 496 SENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR-PAGPAGDEP 554 + EE T P P +P E P+ A P +EPA + P P PA PA P Sbjct: 1084 AVPTPEEPTS----PAAAVP-TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138 Query: 555 AESPSETPGPRPAGPAGDEPAES------PSETPGPSPAGPTRDEPAESPSETPG----P 604 +P E P PA P +E A + P E+ P+ A PT PAES S Sbjct: 1139 --TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT---PAESASFAAVVATLE 1193 Query: 605 RPAGPAGDEPAESP-----SETPGPRPAGPAGDEPAE------SPSETPGPSPAGPTRDE 653 P PA P + E P + P +EPA +P E P+ A PT +E Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE 1253 Query: 654 PAKAGEAAELQDAEVESSAKS 674 P + AA L E+ S A S Sbjct: 1254 PTSSA-AAVLTPEELSSPAAS 1273 Score = 74.3 bits (181), Expect = 3e-13 Identities = 62/198 (31%), Positives = 78/198 (39%), Gaps = 25/198 (12%) Query: 501 EEDTEGRTGPKEGTPGSPSET-PGPS-PAGPAGDEPAESPSETPGPRPAGPAGDEPAE-- 556 E DT P SP+ P P P PA P +P E P A P +EP Sbjct: 986 EPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP--TPEEPTSPAAAVPPPEEPTSPA 1043 Query: 557 ----SPSETPGPRPAGPAGDEPAE------SPSETPGPSPAGPTRDEPAE------SPSE 600 +P E P A P +EP +P E P+ A PT +EP +P E Sbjct: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103 Query: 601 TPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659 P A P +EPA + P P PA PA P +P E P+PA PT +E A A Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP--TPEEPAFPAPAVPTPEESASAAV 1161 Query: 660 AAELQDAEVESSAKSGKP 677 A + +A P Sbjct: 1162 AVPTPEESASPAAAVPTP 1179 Score = 73.9 bits (180), Expect = 4e-13 Identities = 67/213 (31%), Positives = 87/213 (40%), Gaps = 25/213 (11%) Query: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521 +E A +AAV + T A P P + EE T +P + T Sbjct: 998 EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPT---------SPAAAVPT 1048 Query: 522 PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSE 580 P P PA P +P E P A P +EP + P P P PA P +P E Sbjct: 1049 P-EEPTSPAAAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--TPEE 1103 Query: 581 TPGPSPAGPTRDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGDEPAE--- 636 P+ A PT +EPA + P P PA PA P +P E P PA P +E A Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP--TPEEPAFPAPAVPTPEESASAAV 1161 Query: 637 ---SPSETPGPSPAGPTRDEPAK-AGEAAELQD 665 +P E+ P+ A PT E A A A L++ Sbjct: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194 Score = 71.6 bits (174), Expect = 2e-12 Identities = 66/224 (29%), Positives = 86/224 (38%), Gaps = 27/224 (12%) Query: 461 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK-AGHSENGVEEDTEGRTGPKEGTPGSPS 519 V EG AAV+S A+A + G AG S ++GTP P Sbjct: 916 VPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV 975 Query: 520 ETPGPSPAGPAGDEPA----ESPSETPGPRPAGPAGDEPAE------SPSETPGPRPAGP 569 TP + P + A +P E P A P +EP +P E P A P Sbjct: 976 -TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034 Query: 570 AGDEPAE------SPSETPGPSPAGPTRDEPAE------SPSETPGPRPAGPAGDEPAES 617 +EP +P E P+ A PT +EP +P E P A P +EP Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094 Query: 618 PSETPGP-RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA 660 + P P P PA P +P E P+ A PT +EPA A Sbjct: 1095 AAAVPTPEEPTSPAAAVP--TPEEPASPAAAVPTPEEPASPAAA 1136 Score = 44.7 bits (104), Expect = 3e-04 Identities = 40/171 (23%), Positives = 56/171 (32%), Gaps = 10/171 (5%) Query: 508 TGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 567 + P+E P + + AG P + P E +P+ T Sbjct: 927 SSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEE 986 Query: 568 GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRP 626 +P E P+ A PT +EP + P P P PA P P P Sbjct: 987 PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-------PPEEP 1039 Query: 627 AGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 PA P +P E P+ A PT +EP A + +A P Sbjct: 1040 TSPAAAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 74.3 bits (181), Expect = 3e-13 Identities = 51/153 (33%), Positives = 65/153 (42%), Gaps = 17/153 (11%) Query: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 564 +G P++G P+E+P P P P P P P PA P E + P P P Sbjct: 9 QGTAPPQDGE--QPAESPEPPPPWPP-------PPPPPAPPPAPPLLSEASPEPIPEPCP 59 Query: 565 RPA-GPAGDEPAESPSET-PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETP 622 A GP + +ES +E P+P EPA P+ P P PA EPA P+ P Sbjct: 60 ELAPGPCPEATSESATELYTEPTP------EPATEPASEPAPEPATEPAPEPATEPAPEP 113 Query: 623 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655 P PA + EP P+ P PA E A Sbjct: 114 APEPATESAPEPTPEPALESVPEPAPELTPEVA 146 Score = 72.0 bits (175), Expect = 2e-12 Identities = 54/165 (32%), Positives = 65/165 (39%), Gaps = 16/165 (9%) Query: 501 EEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA-GPAGDEPAESPS 559 E+ E P P P P P PA P E + P P P A GP + +ES + Sbjct: 18 EQPAESPEPPPPWPP--PPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESAT 75 Query: 560 ET---PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAE 616 E P P PA EPA P+ P P EPA P+ P P PA + EP Sbjct: 76 ELYTEPTPEPATEPASEPAPEPATEPAP--------EPATEPAPEPAPEPATESAPEPTP 127 Query: 617 SPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAA 661 P+ P PA P +P P P+P T P EAA Sbjct: 128 EPALESVPEPAPEL--TPEVAPELAPEPTPEPVTELAPEFCPEAA 170 Score = 59.3 bits (142), Expect = 1e-08 Identities = 46/150 (30%), Positives = 54/150 (36%), Gaps = 18/150 (12%) Query: 518 PSETPGPSP--AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPA 575 P PGP P + E P+ P PA EPA P+ P PA EPA Sbjct: 59 PELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPA 118 Query: 576 ESPSETPGPSPAGPTRDEPAE------SPSETPGPRPAGPAGDEPAESPSETP--GPRPA 627 + P P PA + EPA +P P P P P P P P PA Sbjct: 119 TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPA 178 Query: 628 GPAGDEPAE--------SPSETPGPSPAGP 649 P + SPS +P PSP P Sbjct: 179 PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208 Score = 54.7 bits (130), Expect = 3e-07 Identities = 45/150 (30%), Positives = 56/150 (37%), Gaps = 15/150 (10%) Query: 486 APSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR 545 AP P+A SE+ E TE P P+ P PA EPA P+ P Sbjct: 62 APGPCPEAT-SESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPA----PE 116 Query: 546 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDE--PAESPSETPG 603 PA + EP P+ P PA E A + P P P E P +P P Sbjct: 117 PATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176 Query: 604 PRP--------AGPAGDEPAESPSETPGPR 625 P P G + + SPS +P PR Sbjct: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPR 206 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 73.9 bits (180), Expect = 4e-13 Identities = 107/369 (28%), Positives = 128/369 (34%), Gaps = 106/369 (28%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPL----ERSQGDEAG 367 G PG P GP +G G R D+GP R+ E GP E+ EAG Sbjct: 805 GPPGPP-----------GPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAG 853 Query: 368 GHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTG 427 G PP PGPQ I L L G S+G G Sbjct: 854 TAG------------------------PPGTPGPQGLLGAPGI-LGLPG---SRGE--RG 883 Query: 428 TQEVGGQ--DPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSP 485 V G +PG PLG AG A GA GSP Sbjct: 884 LPGVAGAVGEPG--------PLGI---------------AGPPGARGPPGA-----VGSP 915 Query: 486 APSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGP 544 +G P +AG N + GR +G PG E P GP G A P GP Sbjct: 916 GVNGAPGEAGRDGNPGNDGPPGR----DGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGP 971 Query: 545 R----------PAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSETPG---------- 583 P+GP G A P GP+ G G+ + P PG Sbjct: 972 AGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGL 1031 Query: 584 PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSET 641 P AG D+ A GPR PAGP+G + + PG PAG G + + P+ Sbjct: 1032 PGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGP 1091 Query: 642 PG-PSPAGP 649 PG P P GP Sbjct: 1092 PGPPGPPGP 1100 Score = 67.4 bits (163), Expect = 4e-11 Identities = 93/291 (31%), Positives = 115/291 (39%), Gaps = 39/291 (13%) Query: 398 EPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDP----GEAVQPCRQPLGARVAD 453 EPGP + S+ E G A QG +E G + P G A P P G R + Sbjct: 347 EPGP-AGSKGESGNKGEPGSAGPQGPPGPSGEE-GKRGPNGEAGSAGPP--GPPGLRGSP 402 Query: 454 KVRKRRKVDEGAGDSAAVASGGAQTLA-LAGSPAPSGHP-KAGHSENGVEEDTEGRTGP- 510 R D AG S GA A + G +G P + G + G GP Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPA 462 Query: 511 -KEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPA- 567 KEG G P P P GPAG PGP+ P G G + + G R A Sbjct: 463 GKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAP 522 Query: 568 GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG----PRPAGPAGD--EPAES--PS 619 GP G+ A+ P P P G + + P PG P P+GPAG+ +P E Sbjct: 523 GPDGNNGAQGP-----PGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHG 577 Query: 620 ETPGPRPAGPAGDE--PAESPSETP-------GPS-PAGP--TRDEPAKAG 658 E P PAGP G+ P ES + P GPS P GP + EP G Sbjct: 578 EFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVG 628 Score = 65.5 bits (158), Expect = 2e-10 Identities = 107/414 (25%), Positives = 138/414 (33%), Gaps = 74/414 (17%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQD 354 P +P P+ + G G+P S G +KG G +GP S E Sbjct: 326 PRGIPGPVGAAGATGARGLVGEPGPAGSK-----GESGNKGEPGSAGPQGPPGPSGEEGK 380 Query: 355 AGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIA--- 411 GP EAG G P L + R PG + AS + Sbjct: 381 RGP-----NGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPN 435 Query: 412 -----------LNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR-QPLGAR-----VADK 454 + G S G++ +E PG +P P GAR + Sbjct: 436 GDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFP 495 Query: 455 VRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEG 513 K D G GD GA+ G+P P G+ A + +G G ++G Sbjct: 496 GPKGPTGDPGKNGDKGHAGLAGAR-----GAPGPDGNNGAQGPPG--PQGVQGGKG-EQG 547 Query: 514 TPGSPSETPGPSPAGPAGD--EPAESP--SETPGPRPAGPAGDEPAESPSETPGPRPAGP 569 PG P P P+GPAG+ +P E E P PAGP G+ P E+ P GP Sbjct: 548 PPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGP--PGESGAAGPTGP 605 Query: 570 AGDEPAESPSETPG----PSPAGPTRDEPAESPSETPGPRPAG----------------- 608 G P G P G PS PG R A Sbjct: 606 IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGE 665 Query: 609 ---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659 P D +P P PAG GD E+ + P PAGP R P + GE Sbjct: 666 IGNPGRDGARGAPGAVGAPGPAGATGDR-GEAGAAGPA-GPAGP-RGSPGERGE 716 Score = 63.9 bits (154), Expect = 5e-10 Identities = 65/204 (31%), Positives = 76/204 (37%), Gaps = 32/204 (15%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 G+P G P A ENG T G+TG + G PG P PAG G + + P Sbjct: 193 GAPGVKGEPGAP-GENG----TPGQTGAR-GLPGERGRVGAPGPAGARGSDGSVGPVGPA 246 Query: 543 GP-RPAGPAGDEPAESP-SETPGPRPAGPAGDEPAESPSETPGPS-PAGPTRDEPAESPS 599 GP AGP G A P E AGPAG PG S P GP + A + Sbjct: 247 GPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT 306 Query: 600 ET---------------PGPR----PAGPAGDEPAESPSETPGPR----PAGPAGDEPAE 636 PGPR P G AG A PGP +G G+ + Sbjct: 307 GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSA 366 Query: 637 SPSETPGPSPAGPTRDEPAKAGEA 660 P PGPS R +AG A Sbjct: 367 GPQGPPGPSGEEGKRGPNGEAGSA 390 Score = 63.2 bits (152), Expect = 8e-10 Identities = 67/211 (31%), Positives = 80/211 (37%), Gaps = 40/211 (18%) Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESP 538 L+G P G+P A NG+ +G G G PG P P P G AG A Sbjct: 290 LSGPVGPPGNPGA----NGLT-GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGL 344 Query: 539 SETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESP------SETPGP-----SP 586 PG PAG G+ + + GP+ P GP+G+E P + PGP SP Sbjct: 345 VGEPG--PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSP 402 Query: 587 A--------------GPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PRPAGPA 630 GP A P+ GP AG G+ P PG P GPA Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPA 462 Query: 631 GDE-PAESPSETPGPSPAGP--TRDEPAKAG 658 G E P P P P GP R EP G Sbjct: 463 GKEGPVGLPGIDGRPGPIGPAGARGEPGNIG 493 Score = 59.3 bits (142), Expect = 1e-08 Identities = 103/368 (27%), Positives = 124/368 (33%), Gaps = 47/368 (12%) Query: 312 EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAG-------------PL 358 E G PG E+ G T GP S+G GP EP G P Sbjct: 590 ERGPPG----ESGAAGPT-GPIGSRGPSG-PPGPDGNKGEPGVVGAVGTAGPSGPSGLPG 643 Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSAS--EVEKIALNLEG 416 ER GG GE L + + PGP A+ E A G Sbjct: 644 ERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAG 703 Query: 417 CALSQGSLRTGTQ-EVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGG 475 A +GS G + EVG P P GA + R G++ V G Sbjct: 704 PAGPRGS--PGERGEVGPAGPNGFAGPA----GAAGQPGAKGERGAKGPKGENGVVGPTG 757 Query: 476 AQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGP--KEGTPGSPSETPGPSPAGPAGD 532 + AG P+G P AG +G G G + G PG + P P GPAG Sbjct: 758 P--VGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGK 815 Query: 533 EPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP--AGPT 590 E P G P G G+ A P G + GP+G+ P TPGP P Sbjct: 816 EGLRGPRGDQG--PVGRTGEVGAVGPPGFAGEK--GPSGEAGTAGPPGTPGPQGLLGAPG 871 Query: 591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG-- 648 S E P AG G+ + PG R GP G SP P AG Sbjct: 872 ILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGAR--GPPG--AVGSPGVNGAPGEAGRD 927 Query: 649 --PTRDEP 654 P D P Sbjct: 928 GNPGNDGP 935 Score = 49.7 bits (117), Expect = 9e-06 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 9/132 (6%) Query: 528 GPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587 GPAGD PGP P D P P P P G G+ A+ + G P Sbjct: 33 GPAGDRGPRGERGPPGP-PGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91 Query: 588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647 P P P P G G PA P E P GPAG A P+ PG + Sbjct: 92 PMGLMGPRGPPGAAGAPGPQGFQG--PAGEPGE---PGQTGPAG---ARGPAGPPGKAGE 143 Query: 648 GPTRDEPAKAGE 659 +P + GE Sbjct: 144 DGHPGKPGRPGE 155 Score = 48.1 bits (113), Expect = 3e-05 Identities = 49/156 (31%), Positives = 55/156 (35%), Gaps = 19/156 (12%) Query: 497 ENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEP 554 E V + G GP+ G PG P P GP G P PGP G Sbjct: 27 EETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPG------PPGPPGPPGLGGNFAAQ 80 Query: 555 AESPSETPGPRPAGPAGDEPAESPSETPGPSPAG--PTRDEPAESPSETPGPR----PAG 608 + GP P G G P P P P G EP E P +T GP PAG Sbjct: 81 YDGKGVGLGPGPMGLMG--PRGPPGAAGAPGPQGFQGPAGEPGE-PGQT-GPAGARGPAG 136 Query: 609 PAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG 643 P G + PG P G G + A TPG Sbjct: 137 PPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPG 172 Score = 47.8 bits (112), Expect = 3e-05 Identities = 57/198 (28%), Positives = 71/198 (35%), Gaps = 37/198 (18%) Query: 483 GSPAPSGHPKAGHSEN--------GVEEDTEGRTGPKEGTPGSPSETPGPS----PAGPA 530 G P P G P G + G+ G GP+ G PG+ PGP PAG Sbjct: 63 GPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR-GPPGAAG-APGPQGFQGPAGEP 120 Query: 531 GDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPAG 588 G+ P+ GP P G AG++ PG R G G + A TPG P G Sbjct: 121 GEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGER--GVVGPQGARGFPGTPGLPGFKG 178 Query: 589 PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----------------PRPAGPAGD 632 + PG G G+ A + TPG P PAG G Sbjct: 179 IRGHNGLDGLKGQPGA--PGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGS 236 Query: 633 EPAESPSETPGP-SPAGP 649 + + P GP AGP Sbjct: 237 DGSVGPVGPAGPIGSAGP 254 Score = 45.1 bits (105), Expect = 2e-04 Identities = 54/165 (32%), Positives = 65/165 (39%), Gaps = 20/165 (12%) Query: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG--PRPAGPAGDEPAESPSETPG 563 GR G ++G G P P P G G+ A+ + G P P G G P P Sbjct: 51 GRDG-EDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMG--PRGPPGAAGA 107 Query: 564 PRP---AGPAGDEPAESPSETPGPS----PAGPTRDEPAESPSETPG-PRPAGPAGDEPA 615 P P GPAG EP E P +T GP+ PAGP + PG P G G + A Sbjct: 108 PGPQGFQGPAG-EPGE-PGQT-GPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGA 164 Query: 616 ESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659 TPG P G G + PG A + EP GE Sbjct: 165 RGFPGTPGLPGFKGIRGHNGLDGLKGQPG---APGVKGEPGAPGE 206 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 73.9 bits (180), Expect = 4e-13 Identities = 99/356 (27%), Positives = 125/356 (35%), Gaps = 46/356 (12%) Query: 312 EEGSPGDPDHEASTQGRTC-GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA-GGH 369 E GSPG P R GP S G + GP S P GP + A G Sbjct: 862 ERGSPGGPGAAGFPGARGLPGPPGSNG----NPGPPGPSGSPGKDGPPGPAGNTGAPGSP 917 Query: 370 GEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQ 429 G P+ + + +K + PP PGP L + G ++G G Sbjct: 918 GVSGPKGDAGQPGEKGS---PGAQGPPGAPGP----------LGIAGITGARGL--AGPP 962 Query: 430 EVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSG 489 + G Q + G A+ + R G + G G+P G Sbjct: 963 GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP--GRDGNPGSDG 1020 Query: 490 HPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGP-SPAGPAGDEPAESPSETPGPRPA- 547 P S G + E + G PG P PGP PAG +GD P+ GP A Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGP-PGPVGPAGKSGDRGESGPA---GPAGAP 1076 Query: 548 GPAGDEPAESPSETPGPR-PAGPAGDEPAES-------PSETPGPSPAGPTRDEPAESPS 599 GPAG A P GPR G G+ A P P GP + A Sbjct: 1077 GPAGSRGAPGPQ---GPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP 1133 Query: 600 ETPGPR-PAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG----PSPAGP 649 GPR P GP+G + S PGP P GP G+ +PG P P GP Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP 1189 Score = 67.8 bits (164), Expect = 3e-11 Identities = 69/226 (30%), Positives = 82/226 (36%), Gaps = 36/226 (15%) Query: 472 ASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGR-TGPKEGTPGSPSETPGPSPAGPA 530 A G A AG P G P G G+ G + K G PGS E+ P P GP+ Sbjct: 511 APGPAGPRGAAGEPGRDGVP-GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS 569 Query: 531 GDEPAESPSETPGPRP-----------AGPAGDEPAESPSET--PGPR----PAGPAGDE 573 G PGP+ GP G P P + GP+ P GP GD+ Sbjct: 570 GPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDK 629 Query: 574 PAESPSETPGPSPAGPTRDEPAES--PSETPGPR-----PAGPAGDEPAESPSE------ 620 P G T P E+ P E PGP+ P P G A +P E Sbjct: 630 GDTGPPGPQGLQGLPGTGGPPGENGKPGE-PGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688 Query: 621 --TPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAEL 663 PG R AGP G E + + PGP A T GE L Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL 734 Score = 67.8 bits (164), Expect = 3e-11 Identities = 108/369 (29%), Positives = 127/369 (34%), Gaps = 65/369 (17%) Query: 313 EGSPGDPDHEASTQGRTC--GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHG 370 +G PG P + + GR GP +G V P P+ D P + E GG G Sbjct: 548 DGKPGPPGSQGES-GRPGPPGPSGPRGQPGVMGFPGPKG---NDGAP---GKNGERGGPG 600 Query: 371 EDRPEPLSPKESKKRKLELSRREQP-PTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQ 429 P+ K E + P PT PG L+G GT Sbjct: 601 GPGPQGPPGKNG-----ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLP--------GT- 646 Query: 430 EVGGQDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPS 488 G PGE +P P G A G GD+ A G LAG+P Sbjct: 647 ---GGPPGENGKPGEPGPKGDAGAPGA------PGGKGDAGAPGERGPP--GLAGAPGLR 695 Query: 489 GHPKAGHSENGVEEDTEGRTGPK--EGTPG---SPSETPGPSPAGPAGDEPAESPSETPG 543 G E G + G GP GTPG P E G GP GD+ E G Sbjct: 696 GGAGPPGPEGG--KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK-----GEPGG 748 Query: 544 PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSET 601 P G G + P+ GP PAG GD + PG P AGP R P E ET Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGD---KGEGGAPGLPGIAGP-RGSPGER-GET 803 Query: 602 PGPRPAG----------PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR 651 P PAG P G +P E P G AG P+ PGP R Sbjct: 804 GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863 Query: 652 DEPAKAGEA 660 P G A Sbjct: 864 GSPGGPGAA 872 Score = 66.6 bits (161), Expect = 7e-11 Identities = 63/204 (30%), Positives = 81/204 (39%), Gaps = 31/204 (15%) Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 G+P +G P G E G + +G GP PG G PAGP G + + +P Sbjct: 813 GAPGQNGEP-GGKGERGAPGE-KGEGGP----PGVAGPPGGSGPAGPPGPQGVKGERGSP 866 Query: 543 G-------------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGP-SPA 587 G P P G G+ PS +PG P GPAG+ A GP A Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDA 926 Query: 588 GPTRDEPAESPSETPG-PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPS 645 G ++ + PG P P G AG A + PG P P G G + + S PG + Sbjct: 927 GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGAN 986 Query: 646 -------PAGPTRDEPAKAGEAAE 662 P GP + P AG A E Sbjct: 987 GLSGERGPPGP-QGLPGLAGTAGE 1009 Score = 64.7 bits (156), Expect = 3e-10 Identities = 72/249 (28%), Positives = 86/249 (34%), Gaps = 54/249 (21%) Query: 470 AVASGGAQTLALAGSPAPSGH-----PKAGHSENGVE--EDTEGRTGPKEGTPGSPSET- 521 A A+G AG P +G P+ E G+ +G G K+G+PG P Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDG-KDGSPGEPGANG 477 Query: 522 -PGPS----------PAGPAGDEPAESPS-ETPGPRPAGPAG--DEPAES---------- 557 PG + PAGP G + P+ E P PAGP G EP Sbjct: 478 LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRG 537 Query: 558 -PSETPGPRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETP------------- 602 P GP G G ++ S PG P P+GP R +P P Sbjct: 538 MPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGP-RGQPGVMGFPGPKGNDGAPGKNGER 596 Query: 603 ----GPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAKA 657 GP P GP G P PGP P G GD P G G E K Sbjct: 597 GGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP 656 Query: 658 GEAAELQDA 666 GE DA Sbjct: 657 GEPGPKGDA 665 Score = 64.3 bits (155), Expect = 3e-10 Identities = 68/235 (28%), Positives = 81/235 (34%), Gaps = 53/235 (22%) Query: 464 GAGDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEE----DTEGRTGP-------- 510 G G+ GA L A G P P+G A G E +G GP Sbjct: 394 GKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG 453 Query: 511 ------------KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-PRPAGPAGDEPAES 557 K+G+PG P P AG G P+ G P GPAG+ A Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513 Query: 558 PSETPGPRPAGPAGDEPAESPSETPG-----PSPAGPTRD---EPAESPSETPGPRPAGP 609 P+ GPR G AG+ + PG SP GP D P S E+ P P GP Sbjct: 514 PA---GPR--GAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568 Query: 610 AGDEPAESPSETPGPR--------------PAGPAGDEPAESPSETPGPSPAGPT 650 +G PGP+ P GP P ET P GPT Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623 Score = 63.5 bits (153), Expect = 6e-10 Identities = 102/389 (26%), Positives = 129/389 (33%), Gaps = 67/389 (17%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373 GSPG + G K G R GP P AG GD+ G Sbjct: 735 GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG---PPGPAG----QPGDKGEGGAPGL 787 Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433 P P+ S + E PGP A G +G ++ G Sbjct: 788 PGIAGPRGSPGERGETG-------PPGPAGFPG----APGQNGEPGGKGERGAPGEKGEG 836 Query: 434 QDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQ----TLALAGSPAPS 488 PG A P P G V+ R G G + + G + G P PS Sbjct: 837 GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896 Query: 489 GHP----KAGHSENGVEEDTEGRTGPK--------EGTPGSPSETPGPSPAGPAGDEPAE 536 G P G + N + G +GPK +G+PG+ P P G AG A Sbjct: 897 GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956 Query: 537 SPSETPG-PRPAGPAGDEPAESPSETPGPR-------PAGPAG--------DEPAES--- 577 + PG P P G G + + S PG P GP G EP Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016 Query: 578 -----PSETPGPSPAGPTRDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAG 631 P P G + + PG P P GP G PA + PAGPAG Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG--PAGKSGDRGESGPAGPAG 1074 Query: 632 DEPAESPSETPG-PSPAGPTRDEPAKAGE 659 A P+ + G P P GP R + + GE Sbjct: 1075 ---APGPAGSRGAPGPQGP-RGDKGETGE 1099 Score = 58.5 bits (140), Expect = 2e-08 Identities = 72/251 (28%), Positives = 80/251 (31%), Gaps = 78/251 (31%) Query: 467 DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSP 526 DS V SG A LAG P P+G P G GP GT G P P Sbjct: 156 DSYDVKSGVAVG-GLAGYPGPAGPP--------------GPPGPP-GTSGHPGSPGSPGY 199 Query: 527 AGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPGPRPA-------GPAG---- 571 GP G+ PS PGP P+GPAG + PG R GPAG Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259 Query: 572 -------------DEPAES-----------PSETPGPSPAGPTRDEPAESPSETPG-PRP 606 E E+ P E P P GP R P E PG P Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP-RGAPGERGR--PGLPGA 316 Query: 607 AGPAGDEPAESPSETPGPR-------------------PAGPAGDEPAESPSETPGPSPA 647 AG G++ A PGP PAG G A PGP Sbjct: 317 AGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGH 376 Query: 648 GPTRDEPAKAG 658 + P G Sbjct: 377 AGAQGPPGPPG 387 Score = 57.4 bits (137), Expect = 4e-08 Identities = 62/204 (30%), Positives = 76/204 (37%), Gaps = 30/204 (14%) Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540 + G P GH + NG + +T G G K G G P E P P GP G A Sbjct: 256 IPGFPGMKGH-RGFDGRNGEKGET-GAPGLK-GENGLPGENGAPGPMGPRG---APGERG 309 Query: 541 TPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAES------PSETPGPSPAGPTRD 592 PG P AG G++ A PGP P G AG + P+ +PG + A R Sbjct: 310 RPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRG 369 Query: 593 EP-------AESPSETPGPRPAGPAGDEPAESPSETPGPR-------PAGPAGDEPAESP 638 EP A+ P PG G G + P+ PG P GPAG A Sbjct: 370 EPGPQGHAGAQGPPGPPGIN--GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL 427 Query: 639 SETPGPSPAGPTRDEPAKAGEAAE 662 G + EP GE E Sbjct: 428 RGGAGEPGKNGAKGEPGPRGERGE 451 Score = 53.1 bits (126), Expect = 8e-07 Identities = 50/178 (28%), Positives = 59/178 (33%), Gaps = 22/178 (12%) Query: 505 EGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 562 +G GPK G PG P P G G + P P GP P + Sbjct: 102 QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVK 161 Query: 563 G----------PRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSETPGP---- 604 P PAGP G S PG P GP + PS PGP Sbjct: 162 SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI 221 Query: 605 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662 P+GPAG + PG R G G + P+ PG R + GE E Sbjct: 222 GPSGPAGKDGESGRPGRPGER--GLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE 277 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 73.2 bits (178), Expect = 8e-13 Identities = 99/379 (26%), Positives = 135/379 (35%), Gaps = 54/379 (14%) Query: 343 EGPQPR--SVEPQDAGPLERSQGDEAGGHGEDRP-----EPLSPKESK---KRKLELS-R 391 + P P SV PQ P + G G D P P+SP E+ + L Sbjct: 792 DSPSPLGVSVSPQTKRPPTKK-----GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846 Query: 392 REQP-----PTEPGPQSASEVEKIA-LNLEGCALSQGSLRT-GTQEVGGQDPGEAVQ-PC 443 ++ P PT P P+ A + L+ +G L T + G A P Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906 Query: 444 RQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEED 503 + P + + +K R G A+ + GA T A P+P G P + Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966 Query: 504 TEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR--PAGPAGDEPAE--SPS 559 PK G P +PS P+P P P+ TP P+ P PA P+ SP+ Sbjct: 967 AATPPSPKGG-PATPSPKGAPTPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPA 1024 Query: 560 ETPGPRPAG--PAGDEPAE--SPSETPGPS----------------PAGPTRDEPAESPS 599 TP P+ A PA P+ SP+ TP P PA P+ P+ Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084 Query: 600 ETPGPRPAGPAGDEPAESP---SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAK 656 TP GPA P +P + TP P P G P + TP +P P Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143 Query: 657 AGEAAELQDAEVESSAKSG 675 + A A S K G Sbjct: 1144 PPKGAPTTPAATPPSPKGG 1162 Score = 72.4 bits (176), Expect = 1e-12 Identities = 95/375 (25%), Positives = 133/375 (35%), Gaps = 71/375 (18%) Query: 347 PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG------ 400 P+ +D+G + + D P PL S + K +PPT+ G Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK-------RPPTKKGSAGPDT 819 Query: 401 ----------PQSASEVEKIALNLEGCALSQGSLRTGT--QEVGGQDP---------GEA 439 P AS + + +L+ +G S + + T G P G Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879 Query: 440 VQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENG 499 + P P + V K + A++ + +PAP G P + Sbjct: 880 LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS------ 933 Query: 500 VEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 559 PK G P P+ TP GPA P +P+ P P P G SP Sbjct: 934 --------PSPK-GAPTPPAATPPSPKGGPATPSPKWAPTP-PAATPPSPKGGPATPSPK 983 Query: 560 ETPGPRPAGPAGDE--PAESPSETPGPSPAGPTRDEPAESPSETPGPRPAG--PAGDEPA 615 P P A P + PA +PS P+P T P SP+ TP P+ A PA P+ Sbjct: 984 GAPTPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042 Query: 616 E--SPSETPGPR--PAGPAGDEPA-----ESPSETPGPSPAGPTRDEPAKAGEA------ 660 SP+ TP P+ P PA P+ +PS P+P T P K G A Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP-KGGPATPSPKG 1101 Query: 661 AELQDAEVESSAKSG 675 A + A S K G Sbjct: 1102 APMPPAATPPSPKGG 1116 Score = 68.6 bits (166), Expect = 2e-11 Identities = 62/221 (28%), Positives = 80/221 (36%), Gaps = 21/221 (9%) Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS 525 G A + GA T P+P G P A +G + P TP SP +P + Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGSPAA-------TPFPKGASTPPAATPPSPKGSPAAT 1050 Query: 526 PAGPAGDEPAESPSETPGPR--PAGPAGDEPAESPSETPGPRPAGPAGDEPAESP---SE 580 P P G P + P P+ PA P+ P+ TP GPA P +P + Sbjct: 1051 PL-PKG-APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108 Query: 581 TPGPSPAGPTRDEPAESPSETPGPRPAGPAGD---EPAESPSETPGPRPAGPAGD---EP 634 TP PSP G P + TP P P G P + TP P P G P Sbjct: 1109 TP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167 Query: 635 AESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675 + TP +P P + + A A S K G Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208 Score = 67.8 bits (164), Expect = 3e-11 Identities = 91/383 (23%), Positives = 112/383 (29%), Gaps = 58/383 (15%) Query: 313 EGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGED 372 +G P P + + P KGG P+ P P + G Sbjct: 928 KGIPASPSPKGAPTPPAATPPSPKGGPATPS-PKWAPTPPAATPPSPKGGPATPSPKGAP 986 Query: 373 RPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVG 432 P +P K P P P+ A + +GS G Sbjct: 987 TPPAATPPSPKGG----------PATPSPKGAPTPPAVTP-----PSPKGSPAATPFPKG 1031 Query: 433 GQDPGEAVQPCRQPLGARVADKVRKRRKVDEGA------GDSAAVASGGAQTLALAGSPA 486 P A P P G+ A + K A G A + GA T A P+ Sbjct: 1032 ASTPPAATPP--SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089 Query: 487 PSGHPKAGHSENGVEEDTEGR---------TGPKEGTPGSPSETPGPSPAGPAGDEPAES 537 P G P A S G T P +G P +P+ TP PSP G P + Sbjct: 1090 PKGGP-ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP-PSPKGGLATPPPKG 1147 Query: 538 PSETPGPRPAGPAGD---EPAESPSETPGPRPAGPAGDEPAESPSETPG------PSPAG 588 TP P P G P + TP P P G SP P PSP G Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207 Query: 589 PTRDEPAESPSETPGPRPAGPAGDEPAESPS---ETPGPRPAGPAGDE-----------P 634 + TP P P G SP TP P P G P Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267 Query: 635 AESPSETPGPSPAGPTRDEPAKA 657 A +P G P + P A Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPA 1290 Score = 65.5 bits (158), Expect = 2e-10 Identities = 96/400 (24%), Positives = 124/400 (31%), Gaps = 45/400 (11%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAG 356 P P P + +G P P + + P KGG P P+ A Sbjct: 936 PKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT---PSPKGAPTPPAA 991 Query: 357 PLERSQGDEAGGHGEDRPEPL-----SPKESKK-----RKLELSRREQPPTEPGPQSASE 406 +G A + P P SPK S + PP+ G +A+ Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051 Query: 407 VEKIALNLEGCALSQGSLRTGTQEV-GGQDPGEAVQPCRQPLGARVADK---VRKRRKVD 462 + K A L T + G P A P + A + K + Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111 Query: 463 EGAGDSAAVASGGAQTLALAGSPAPSGH-----PKAGHSENGVEEDTEG---RTGPKEGT 514 G A GA T A P+P G PK + + T P +G Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171 Query: 515 PGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS---ETPGPRPAGPAG 571 P +P+ TP PSP G + TP P P G SP TP P P G Sbjct: 1172 PTTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230 Query: 572 DEPAESPS---ETPGPSPAGPTRDEPAESPSETPGPRPAGPAG---------DEPAESPS 619 SP TP +P P P P P A P + A +P+ Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290 Query: 620 ETPGPRP-AGPAGDEP--AESPSETPGPSPAGPTRDEPAK 656 P P GPA P A +P PSP G P K Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330 Score = 64.3 bits (155), Expect = 3e-10 Identities = 53/185 (28%), Positives = 66/185 (35%), Gaps = 20/185 (10%) Query: 484 SPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG 543 +P+P G P + + PK G P +P+ TP PSP G + TP Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPK-GAPTTPAATP-PSPKGGLATPSPKGAPTTPA 1245 Query: 544 PRPAGPAGDEPAESPSETPGPRPAGPAG---------DEPAESPSETPGPSPAGPTRDEP 594 P P G P P P A P + A +P+ PSP G P Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305 Query: 595 ---AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDE--PAESPSETPGP----S 645 A +P P P G G P + P P P G PA +PS GP S Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365 Query: 646 PAGPT 650 GPT Sbjct: 1366 KEGPT 1370 Score = 62.4 bits (150), Expect = 1e-09 Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 60/225 (26%) Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETP--- 522 G A + GA T A P+P G P T P +G P P+ TP Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPA---------------TPPPKGAPTPPAATPPSL 1274 Query: 523 -----------GPSPA---------GPAGDEP--AESPSETPGPRPAGPAGDEPAESPSE 560 P+PA GPA P A +P P P G G P + Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334 Query: 561 TPGPRPAGPAGDE--PAESPSETPGP----SPAGPTRDEPAESPSETPGPR------PAG 608 P P P G PA +PS GP S GPT PA +PS GP G Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT--PPAATPSHKGGPAMTPPSPKRG 1392 Query: 609 PAGDEPAESPSE------TPGPRPAGPAGDEPAESPSETPGPSPA 647 PA P P+ +P PA P E A +PS+ PA Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437 Score = 61.2 bits (147), Expect = 3e-09 Identities = 69/216 (31%), Positives = 82/216 (37%), Gaps = 45/216 (20%) Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS 525 G A GA T A P+P G P T P +G P P+ TP PS Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPG---------------TPPPKGAPTPPAVTP-PS 1342 Query: 526 PAGPAGDEPAESPSETPGPR-PAGPAGDEP-AESPSETPGPR------PAGPAGDEPAES 577 P G PA +PS GP P+ G P A +PS GP GPA P Sbjct: 1343 PKGTP-TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401 Query: 578 PSE------TPGPSPAGPTRDEPAESPSE--------TPGPRPAGPAGDEPAESPSETPG 623 P+ +P +PA P E A +PS+ TP PA P P+ TP Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA-TPS 1460 Query: 624 PR--PAGPAGDEPAESPSETPGPSPAGPTRDEPAKA 657 + P PA P SP E P P T P KA Sbjct: 1461 SKGDPTLPAVTPP--SPKEPPAPKQVA-TSSSPKKA 1493 Score = 59.7 bits (143), Expect = 9e-09 Identities = 54/195 (27%), Positives = 68/195 (34%), Gaps = 13/195 (6%) Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEG----TPGSPSET 521 G A + GA T A P+P G + PK G +P T Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243 Query: 522 PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPA-ESPSETPGPRPAGPAGDEPAESPSE 580 P +P P G P P P A P + +P P PA P P+ Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303 Query: 581 TP---GPSPAGPTRDEPAESPSETPGPR--PAGPAGDEPAESPSETPGPRPAGPAGDEPA 635 +P P+P T P SP TP P+ P PA P SP TP P+ Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPG-TPPPKGAPTPPAVTPP--SPKGTPTLPATTPSSKGGP 1360 Query: 636 ESPSETPGPSPAGPT 650 +PS GP+P T Sbjct: 1361 TTPSSKEGPTPPAAT 1375 Score = 52.8 bits (125), Expect = 1e-06 Identities = 100/430 (23%), Positives = 142/430 (33%), Gaps = 61/430 (14%) Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG------------GGRVD-- 342 P P P + +GSPG P + + P KG GG Sbjct: 1306 PKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364 Query: 343 --EGPQPRSVEPQDAGPLERSQGDEAGGHGEDRP--EPLSPKESKKRKLELSRREQPPTE 398 EGP P + P G + G P +P SP + LS ++ P T Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV-----IPLSPKKAPATP 1419 Query: 399 PGPQSASEVEKIALNLEGCALSQGSLR----TGTQEVGGQDP---GEAVQPCRQPLGARV 451 + A+ K +L A++ SL+ T + G P G+ P P + Sbjct: 1420 VTREGAATPSKG--DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477 Query: 452 ADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK 511 ++ A A GA TL +P P S T K Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537 Query: 512 EGTPGSPSETPGPSPAGPAGDEPAESPS-ETPGPRPAGPAGDEPAESPSETPGPRPAGPA 570 TP + + P P ++P+ TP PA P+ E + P+ TP P+ Sbjct: 1538 --TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS 1595 Query: 571 GDE-------PAESPSETPGP---SPAGPTRDEPAESPSETPGPRPAGPAG--DEP---- 614 E + SP E P P +P P + +P TP P P+ D P Sbjct: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655 Query: 615 -------AESPSETPG-PRPAGP-AGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQD 665 A P + G P GP A E +P+ P PTR P +A Sbjct: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP 1715 Query: 666 AEVESSAKSG 675 + SAK+G Sbjct: 1716 ICPDPSAKNG 1725 Score = 29.6 bits (65), Expect = 9.5 Identities = 36/148 (24%), Positives = 46/148 (31%), Gaps = 21/148 (14%) Query: 510 PKEGTPGSPS-ETPGPSPAGPAGDEPAESPSET------PGPRPAGPAGDEPAESPSETP 562 P E T P+ E P P P S PGP P P + P Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61 Query: 563 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETP 622 P+ A +P E P P + T P G A + P P+ Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGT-------------ALPLGTAPEAPTFLPNLIG 108 Query: 623 GP-RPAGPAGDEPAESPSETPGPSPAGP 649 P PA A P +P+ PS + P Sbjct: 109 PPISPAALALASPMIAPTLKGTPSSSAP 136 >gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] Length = 280 Score = 72.0 bits (175), Expect = 2e-12 Identities = 48/162 (29%), Positives = 71/162 (43%), Gaps = 4/162 (2%) Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGP 544 P SG + G+ + V E T G GP+E G+P+ TP P + P +P TP Sbjct: 23 PGESGG-RTGNWVSSVGEMT-GPYGPRE--MGTPTLTPSSPPTLTPSNTPTLTPCSTPTL 78 Query: 545 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGP 604 P P+ +P+ TP P P +PS TP +P+ P+ +P+ TP Sbjct: 79 TPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 138 Query: 605 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP 646 P P +PS TP P+ P+ +P+ TP +P Sbjct: 139 TPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTP 180 Score = 65.9 bits (159), Expect = 1e-10 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 5/135 (3%) Query: 514 TPGS-PSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 572 TP S P+ T +P P +PS TP P+ P+ +P+ TP RP Sbjct: 135 TPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS 194 Query: 573 EPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 632 P +PS TP +P+ P +PS TP P+ P+ +P+ TP RP Sbjct: 195 TPTLTPSSTPTLTPSST----PTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSS 250 Query: 633 EPAESPSETPGPSPA 647 P +PS TP +P+ Sbjct: 251 TPTLTPSSTPTLTPS 265 Score = 65.5 bits (158), Expect = 2e-10 Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 1/134 (0%) Query: 514 TPGS-PSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 572 TP S P+ TP +P P +PS TP P+ P+ +P+ T P Sbjct: 95 TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSS 154 Query: 573 EPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 632 P +PS TP +P+ P+ +P+ TP RP P +PS TP P+ Sbjct: 155 TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTL 214 Query: 633 EPAESPSETPGPSP 646 P+ +P+ P +P Sbjct: 215 TPSNTPTLIPSSTP 228 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/131 (28%), Positives = 57/131 (43%) Query: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576 +P TP +P+ P+ +P+ TP P P +PS TP P+ P+ Sbjct: 79 TPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 138 Query: 577 SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 636 +P+ T +P P +PS TP P+ P+ +P+ TP RP P Sbjct: 139 TPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTL 198 Query: 637 SPSETPGPSPA 647 +PS TP +P+ Sbjct: 199 TPSSTPTLTPS 209 Score = 64.7 bits (156), Expect = 3e-10 Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 6/162 (3%) Query: 486 APSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR 545 A HP A E+G GRTG + G + GP G P+ P+ TP Sbjct: 14 AAKEHPMAVPGESG------GRTGNWVSSVGEMTGPYGPREMGTPTLTPSSPPTLTPSNT 67 Query: 546 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR 605 P P +P TP P+ P+ +P+ TP +P P +PS TP Sbjct: 68 PTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 127 Query: 606 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647 P+ P+ +P+ T P P +PS TP +P+ Sbjct: 128 PSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPS 169 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/130 (27%), Positives = 56/130 (43%) Query: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576 +P+ TP +P P +PS TP P+ P+ +P+ TP P P Sbjct: 91 TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTL 150 Query: 577 SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 636 +PS TP +P+ P+ +P+ TP P P + S TP P+ P+ Sbjct: 151 TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSS 210 Query: 637 SPSETPGPSP 646 +P+ TP +P Sbjct: 211 TPTLTPSNTP 220 Score = 63.9 bits (154), Expect = 5e-10 Identities = 37/131 (28%), Positives = 57/131 (43%) Query: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576 +PS TP +P+ P+ +P+ TP P P +PS TP P+ P+ Sbjct: 111 TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSS 170 Query: 577 SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 636 +P+ TP +P P + S TP P+ P+ +P+ TP P P Sbjct: 171 TPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTL 230 Query: 637 SPSETPGPSPA 647 +PS TP +P+ Sbjct: 231 TPSSTPTLTPS 241 Score = 61.2 bits (147), Expect = 3e-09 Identities = 49/177 (27%), Positives = 70/177 (39%), Gaps = 21/177 (11%) Query: 476 AQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGS-----PSETPGPSPAGPA 530 + T L S P+ P + + T R+ TP S PS TP +P+ Sbjct: 113 SSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTP 172 Query: 531 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 590 P+ +P+ TP RP P +PS TP P+ P +PS TP P+ Sbjct: 173 TLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSST----PTLTPSNTPTLIPSSTP 228 Query: 591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647 P+ +P+ TP RP P +PS TP +PS TP +P+ Sbjct: 229 TLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTP------------TLTPSSTPTLTPS 273 Score = 59.7 bits (143), Expect = 9e-09 Identities = 47/172 (27%), Positives = 67/172 (38%), Gaps = 7/172 (4%) Query: 478 TLALAGSPA--PSGHPKAGHSENGVEEDTEGRTGPKEGTPG-SPSETPGPSPAGPAGDEP 534 TL +P PS P S + T TP +PS TP +P+ P Sbjct: 77 TLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTP 136 Query: 535 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594 + +P+ T P P +PS TP P+ P+ +P+ TP P P Sbjct: 137 SSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTP 196 Query: 595 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP 646 +PS TP P+ P +PS TP P+ P+ +P+ TP P Sbjct: 197 TLTPSSTPTLTPS----STPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRP 244 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 71.2 bits (173), Expect = 3e-12 Identities = 109/402 (27%), Positives = 142/402 (35%), Gaps = 52/402 (12%) Query: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-E 359 P P + + E+G+PG P G P +GG D+G + P GP E Sbjct: 644 PGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP--GEGGKPGDQGVPGEAGAPGLVGPRGE 700 Query: 360 RSQGDEAGGHGEDR---PEPLSPKESKKRKLELSRREQPPTEPGPQSASEV--EKIALNL 414 R E G G P L S PP GP + E+ A + Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760 Query: 415 EGCALSQGSL-RTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473 G +G + G + G+D G + P G A+ + AG + A + Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820 Query: 474 GGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPG--SPSETPGPSP- 526 G + G P P+G P + G + + +G G K G PG PS PGP Sbjct: 821 PGER--GETGPPGPAGFAGPPGADGQPGAKGE-QGEAGQKGDAGAPGPQGPSGAPGPQGP 877 Query: 527 ---AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAG-DEPAESPSET 581 GP G A+ P G P AG G P S P P GP+G D P + ++ Sbjct: 878 TGVTGPKGARGAQGPPGATGFPGAAGRVG--PPGSNGNPGPPGPPGPSGKDGPKGARGDS 935 Query: 582 PGPSPAG-PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----------------- 623 P AG P PA P E P GP+G E P G Sbjct: 936 GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 995 Query: 624 --PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662 P P+G G + A S G P P GP P G A E Sbjct: 996 GLPGPSGEPGKQGAPGASGDRGPPGPVGP----PGLTGPAGE 1033 Score = 67.8 bits (164), Expect = 3e-11 Identities = 109/399 (27%), Positives = 131/399 (32%), Gaps = 63/399 (15%) Query: 312 EEGSPGD--PDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA-GG 368 E GSPG P +GRT GP + G D P P P GP A G Sbjct: 316 ENGSPGPMGPRGLPGERGRT-GPAGAAGARGNDGQPGPAG-PPGPVGPAGGPGFPGAPGA 373 Query: 369 HGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRT 426 GE P E + R +P P PGP AS +G ++GS Sbjct: 374 KGEAGPTGARGPEGAQ-----GPRGEPGTPGSPGPAGASGNP----GTDGIPGAKGS--A 422 Query: 427 GTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGS 484 G + G PG P Q + K + G+ G Q G Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ--------TGEPGIAGFKGEQ--GPKGE 472 Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTP--GSPSETPGPSPAGPAGDEPAESPSETP 542 P P+G P+ G EE G G G G P E P G G + P P Sbjct: 473 PGPAG-PQGAPGPAG-EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP 530 Query: 543 GPR-PAGPAGDEPAESPSETPG-------------PRPAGPAGDE-PAESPSETPGPSPA 587 G R P+G AG + A PG P AGP G P+ +P E P P Sbjct: 531 GERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP 590 Query: 588 GPTRDEPAESPSETPGPRPA----GPAGDEPAESP----------SETPGPRPAGPAGDE 633 GP PGP+ A G AG++ ET P GPAG Sbjct: 591 GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA 650 Query: 634 PAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672 PGPS P GE + D V A Sbjct: 651 GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689 Score = 66.2 bits (160), Expect = 9e-11 Identities = 77/279 (27%), Positives = 98/279 (35%), Gaps = 58/279 (20%) Query: 436 PGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHP--K 492 PGE P + L R D + + GA G+ G Q G P G P K Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPK 608 Query: 493 AGHSENGV--EEDTEGRTGPKEGTPGSPSETPGPSPAGPA------GDEPAESPSETPG- 543 + E G E+ G G + G PG ET P GPA G++ A PS G Sbjct: 609 GANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 667 Query: 544 PRPAGPAGD--EPAES--PSETPGPRPAGPAGDEPAESPSETPGPS--------PAGPTR 591 P P GP G+ +P + P E P GP G+ +PG P P Sbjct: 668 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT 727 Query: 592 DEP--AESPSETPGPR-------------------PAGPAGDEPAESPSETPGP------ 624 D P A P+ PG + P G GD + P PG Sbjct: 728 DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787 Query: 625 ----RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659 P GPAG + PGP+ + R P + GE Sbjct: 788 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 826 Score = 65.1 bits (157), Expect = 2e-10 Identities = 106/381 (27%), Positives = 133/381 (34%), Gaps = 62/381 (16%) Query: 309 KVEEEGSPGDPDHEA--STQGRT--CGPEHSKG--GGRVDEG-PQPRSVEPQDAGPLERS 361 K E+G PG P G T GP G G R ++G P P + P Sbjct: 616 KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 675 Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP-PTEPGPQSASEVEKIALNLEGCALS 420 +G + G G P E+ L R E+ P E G A ++ L G + Sbjct: 676 EGGKPGDQGV-------PGEAGAPGLVGPRGERGFPGERGSPGAQGLQG-PRGLPGTPGT 727 Query: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPL-----GARVADKVRKRRKVDEGAGDSAAVASGG 475 G G G PG P Q + A +A R V E + A GG Sbjct: 728 DGP--KGASGPAGP-PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784 Query: 476 AQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPSETPGPSPAGPA 530 G P P+G NG E+ G GP G PG ET P PAG A Sbjct: 785 RGLTGPIGPPGPAG-------ANG-EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 836 Query: 531 GDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589 G A+ G + AG GD A P P GP+G + P+ GP A Sbjct: 837 GPPGADGQPGAKGEQGEAGQKGDAGA--------PGPQGPSGAPGPQGPTGVTGPKGARG 888 Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG----- 643 + P T P AG G + PG P P+G G + A S PG Sbjct: 889 AQGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP 944 Query: 644 --PSPAGPTRDEPAKAGEAAE 662 PAGP P + GE + Sbjct: 945 GLQGPAGP----PGEKGEPGD 961 Score = 64.3 bits (155), Expect = 3e-10 Identities = 77/265 (29%), Positives = 94/265 (35%), Gaps = 43/265 (16%) Query: 435 DPGEAVQP-CRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALAGSPAPSGHPK 492 +PGE +P P+G R + D AG G G P G P Sbjct: 226 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 285 Query: 493 A-GHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSP------------AGPAGDEPAES 537 GH + +G G +G GSP E P P GPAG A Sbjct: 286 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 345 Query: 538 PSETPGPR-PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPG----PSPAG 588 PGP P GP G PG + P G G E A+ P PG P PAG Sbjct: 346 NDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 405 Query: 589 PTRD------EPAESPSETPG-------PRPAGPAGDEPAESPSETPGPR-PAGPAGDEP 634 + + A+ + PG P P GP G + A P G G AG + Sbjct: 406 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 465 Query: 635 AESPSETPGPSPAGPTRDEPAKAGE 659 + P PG PAGP + P AGE Sbjct: 466 EQGPKGEPG--PAGP-QGAPGPAGE 487 Score = 62.4 bits (150), Expect = 1e-09 Identities = 65/224 (29%), Positives = 72/224 (32%), Gaps = 34/224 (15%) Query: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSE 520 ++ G V G + G P P+G P G N E G +GP P Sbjct: 189 EKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM-----GPRG 243 Query: 521 TPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PRPAGPAGDE 573 PGP P P D A P + P GP G PG P G G+ Sbjct: 244 PPGP-PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA 302 Query: 574 PAE-------SPSETPGPSPAGPTRDEPAESPSETPG-----------PRPAGPAGD-EP 614 A SP E P P GP R P E P P PAGP G P Sbjct: 303 GAPGVKGESGSPGENGSPGPMGP-RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 361 Query: 615 AESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658 A P P G AG A P GP T P AG Sbjct: 362 AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 405 Score = 59.7 bits (143), Expect = 9e-09 Identities = 114/413 (27%), Positives = 141/413 (34%), Gaps = 115/413 (27%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371 G+PG P GP G G R D GP R+ EP GP E G G+ Sbjct: 912 GNPGPPGPP--------GPSGKDGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGD 961 Query: 372 DRPE----PLSPKESKKRK----LELSRREQP-PTEPGPQSASEVEKIALNLEGCALSQG 422 D P P P+ ++ L R E+ P PGP S ++ A G G Sbjct: 962 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP-SGEPGKQGAPGASGDRGPPG 1020 Query: 423 SLRTGTQEVGGQDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLAL 481 + +PG P P G A V+ R G++ AV + GA Sbjct: 1021 PVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR------GETGAVGAPGAP--GP 1072 Query: 482 AGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----------------EGTPGSPSET--- 521 GSP P+G P + G E +G GP +G G P E Sbjct: 1073 PGSPGPAG-PTGKQGDRG-EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1130 Query: 522 --------------PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 563 PGPS +GPAG P P P GP+G + A PG Sbjct: 1131 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP-----PGPVGPSGKDGANG---IPG 1182 Query: 564 P-RPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSET 621 P P GP G P+ PG P P GP P P GP D A Sbjct: 1183 PIGPPGPRGRSGETGPAGPPGNPGPPGP--------------PGPPGPGIDMSAF----- 1223 Query: 622 PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKS 674 AG P E GP P R + A G DAEV+++ KS Sbjct: 1224 --------AGLGPREK-----GPDPLQYMRADQAAGG--LRQHDAEVDATLKS 1261 Score = 59.3 bits (142), Expect = 1e-08 Identities = 63/217 (29%), Positives = 71/217 (32%), Gaps = 44/217 (20%) Query: 483 GSPAPSGHPKAGHSENGVEEDT--EGRTGPK-----EGTPGSPSETPGPSPAGPAG---- 531 G P P G P G D +G GP+ GTPG+P P P GP G Sbjct: 120 GPPGPQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN 178 Query: 532 ---------DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE------ 576 DE A P GP G P+ PGP+ EP E Sbjct: 179 FAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGP 238 Query: 577 -SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PRPAG 628 P PGP P P D A P + P GP G PG P G Sbjct: 239 MGPRGPPGP-PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 297 Query: 629 PAGDEPAE-------SPSETPGPSPAGPTRDEPAKAG 658 G+ A SP E P P GP R P + G Sbjct: 298 AKGEAGAPGVKGESGSPGENGSPGPMGP-RGLPGERG 333 Score = 55.1 bits (131), Expect = 2e-07 Identities = 63/219 (28%), Positives = 73/219 (33%), Gaps = 49/219 (22%) Query: 506 GRTGPK--EGTPGS------PSETPGPS-PAG---PAGDEPAESPSETPGPR----PAGP 549 G+ GPK +G PG P PGP PAG P GD + PGPR G Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157 Query: 550 AGDEPAESPSETPGP----------------------------RPAGPAGDEPAESPSET 581 G+ P PGP P GP G P+ Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217 Query: 582 PGPSPAGPTRDEPAESPSETP-GPR-PAGPAGDEPAESPSETPGPR-PAGPAGDEPAESP 638 PGP EP E P GPR P GP G + + PG GP G + A Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277 Query: 639 SETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677 TPG R P G E V+ +SG P Sbjct: 278 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK--GESGSP 314 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 71.2 bits (173), Expect = 3e-12 Identities = 109/402 (27%), Positives = 142/402 (35%), Gaps = 52/402 (12%) Query: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-E 359 P P + + E+G+PG P G P +GG D+G + P GP E Sbjct: 575 PGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP--GEGGKPGDQGVPGEAGAPGLVGPRGE 631 Query: 360 RSQGDEAGGHGEDR---PEPLSPKESKKRKLELSRREQPPTEPGPQSASEV--EKIALNL 414 R E G G P L S PP GP + E+ A + Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691 Query: 415 EGCALSQGSL-RTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473 G +G + G + G+D G + P G A+ + AG + A + Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751 Query: 474 GGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPG--SPSETPGPSP- 526 G + G P P+G P + G + + +G G K G PG PS PGP Sbjct: 752 PGER--GETGPPGPAGFAGPPGADGQPGAKGE-QGEAGQKGDAGAPGPQGPSGAPGPQGP 808 Query: 527 ---AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAG-DEPAESPSET 581 GP G A+ P G P AG G P S P P GP+G D P + ++ Sbjct: 809 TGVTGPKGARGAQGPPGATGFPGAAGRVG--PPGSNGNPGPPGPPGPSGKDGPKGARGDS 866 Query: 582 PGPSPAG-PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----------------- 623 P AG P PA P E P GP+G E P G Sbjct: 867 GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 926 Query: 624 --PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662 P P+G G + A S G P P GP P G A E Sbjct: 927 GLPGPSGEPGKQGAPGASGDRGPPGPVGP----PGLTGPAGE 964 Score = 67.8 bits (164), Expect = 3e-11 Identities = 109/399 (27%), Positives = 131/399 (32%), Gaps = 63/399 (15%) Query: 312 EEGSPGD--PDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA-GG 368 E GSPG P +GRT GP + G D P P P GP A G Sbjct: 247 ENGSPGPMGPRGLPGERGRT-GPAGAAGARGNDGQPGPAG-PPGPVGPAGGPGFPGAPGA 304 Query: 369 HGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRT 426 GE P E + R +P P PGP AS +G ++GS Sbjct: 305 KGEAGPTGARGPEGAQ-----GPRGEPGTPGSPGPAGASGNP----GTDGIPGAKGS--A 353 Query: 427 GTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGS 484 G + G PG P Q + K + G+ G Q G Sbjct: 354 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ--------TGEPGIAGFKGEQ--GPKGE 403 Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTP--GSPSETPGPSPAGPAGDEPAESPSETP 542 P P+G P+ G EE G G G G P E P G G + P P Sbjct: 404 PGPAG-PQGAPGPAG-EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP 461 Query: 543 GPR-PAGPAGDEPAESPSETPG-------------PRPAGPAGDE-PAESPSETPGPSPA 587 G R P+G AG + A PG P AGP G P+ +P E P P Sbjct: 462 GERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP 521 Query: 588 GPTRDEPAESPSETPGPRPA----GPAGDEPAESP----------SETPGPRPAGPAGDE 633 GP PGP+ A G AG++ ET P GPAG Sbjct: 522 GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA 581 Query: 634 PAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672 PGPS P GE + D V A Sbjct: 582 GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620 Score = 66.2 bits (160), Expect = 9e-11 Identities = 77/279 (27%), Positives = 98/279 (35%), Gaps = 58/279 (20%) Query: 436 PGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHP--K 492 PGE P + L R D + + GA G+ G Q G P G P K Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPK 539 Query: 493 AGHSENGV--EEDTEGRTGPKEGTPGSPSETPGPSPAGPA------GDEPAESPSETPG- 543 + E G E+ G G + G PG ET P GPA G++ A PS G Sbjct: 540 GANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 598 Query: 544 PRPAGPAGD--EPAES--PSETPGPRPAGPAGDEPAESPSETPGPS--------PAGPTR 591 P P GP G+ +P + P E P GP G+ +PG P P Sbjct: 599 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT 658 Query: 592 DEP--AESPSETPGPR-------------------PAGPAGDEPAESPSETPGP------ 624 D P A P+ PG + P G GD + P PG Sbjct: 659 DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718 Query: 625 ----RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659 P GPAG + PGP+ + R P + GE Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 757 Score = 65.1 bits (157), Expect = 2e-10 Identities = 106/381 (27%), Positives = 133/381 (34%), Gaps = 62/381 (16%) Query: 309 KVEEEGSPGDPDHEA--STQGRT--CGPEHSKG--GGRVDEG-PQPRSVEPQDAGPLERS 361 K E+G PG P G T GP G G R ++G P P + P Sbjct: 547 KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 606 Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP-PTEPGPQSASEVEKIALNLEGCALS 420 +G + G G P E+ L R E+ P E G A ++ L G + Sbjct: 607 EGGKPGDQGV-------PGEAGAPGLVGPRGERGFPGERGSPGAQGLQG-PRGLPGTPGT 658 Query: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPL-----GARVADKVRKRRKVDEGAGDSAAVASGG 475 G G G PG P Q + A +A R V E + A GG Sbjct: 659 DGP--KGASGPAGP-PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 715 Query: 476 AQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPSETPGPSPAGPA 530 G P P+G NG E+ G GP G PG ET P PAG A Sbjct: 716 RGLTGPIGPPGPAG-------ANG-EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 767 Query: 531 GDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589 G A+ G + AG GD A P P GP+G + P+ GP A Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGA--------PGPQGPSGAPGPQGPTGVTGPKGARG 819 Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG----- 643 + P T P AG G + PG P P+G G + A S PG Sbjct: 820 AQGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP 875 Query: 644 --PSPAGPTRDEPAKAGEAAE 662 PAGP P + GE + Sbjct: 876 GLQGPAGP----PGEKGEPGD 892 Score = 64.3 bits (155), Expect = 3e-10 Identities = 77/265 (29%), Positives = 94/265 (35%), Gaps = 43/265 (16%) Query: 435 DPGEAVQP-CRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALAGSPAPSGHPK 492 +PGE +P P+G R + D AG G G P G P Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 216 Query: 493 A-GHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSP------------AGPAGDEPAES 537 GH + +G G +G GSP E P P GPAG A Sbjct: 217 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 276 Query: 538 PSETPGPR-PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPG----PSPAG 588 PGP P GP G PG + P G G E A+ P PG P PAG Sbjct: 277 NDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 336 Query: 589 PTRD------EPAESPSETPG-------PRPAGPAGDEPAESPSETPGPR-PAGPAGDEP 634 + + A+ + PG P P GP G + A P G G AG + Sbjct: 337 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 396 Query: 635 AESPSETPGPSPAGPTRDEPAKAGE 659 + P PG PAGP + P AGE Sbjct: 397 EQGPKGEPG--PAGP-QGAPGPAGE 418 Score = 63.2 bits (152), Expect = 8e-10 Identities = 91/323 (28%), Positives = 107/323 (33%), Gaps = 45/323 (13%) Query: 370 GEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSL----R 425 G+D +P PK K ++ P PGPQ + E+ G +G+ R Sbjct: 25 GQDVRQP-GPKGQKGEPGDIKDIVGPKGPPGPQGPAG-EQGPRGDRGDKGEKGAPGPRGR 82 Query: 426 TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSA-AVASGGAQTLALA 482 G G PG P LG A ++ DE AG + V G + Sbjct: 83 DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG--FDEKAGGAQLGVMQGPMGPMGPR 140 Query: 483 GSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSET 541 G P P+G P G N E G +GP P PGP P P D A P + Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPM-----GPRGPPGP-PGKPGDDGEAGKPGKA 194 Query: 542 PGPRPAGPAGDEPAESPSETPG-------PRPAGPAGDEPAE-------SPSETPGPSPA 587 P GP G PG P G G+ A SP E P P Sbjct: 195 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 254 Query: 588 GPTRDEPAESPSETPG-----------PRPAGPAGD-EPAESPSETPGPRPAGPAGDEPA 635 GP R P E P P PAGP G PA P P G AG A Sbjct: 255 GP-RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 313 Query: 636 ESPSETPGPSPAGPTRDEPAKAG 658 P GP T P AG Sbjct: 314 RGPEGAQGPRGEPGTPGSPGPAG 336 Score = 59.7 bits (143), Expect = 9e-09 Identities = 114/413 (27%), Positives = 141/413 (34%), Gaps = 115/413 (27%) Query: 314 GSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371 G+PG P GP G G R D GP R+ EP GP E G G+ Sbjct: 843 GNPGPPGPP--------GPSGKDGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGD 892 Query: 372 DRPE----PLSPKESKKRK----LELSRREQP-PTEPGPQSASEVEKIALNLEGCALSQG 422 D P P P+ ++ L R E+ P PGP S ++ A G G Sbjct: 893 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP-SGEPGKQGAPGASGDRGPPG 951 Query: 423 SLRTGTQEVGGQDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLAL 481 + +PG P P G A V+ R G++ AV + GA Sbjct: 952 PVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR------GETGAVGAPGAP--GP 1003 Query: 482 AGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----------------EGTPGSPSET--- 521 GSP P+G P + G E +G GP +G G P E Sbjct: 1004 PGSPGPAG-PTGKQGDRG-EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1061 Query: 522 --------------PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 563 PGPS +GPAG P P P GP+G + A PG Sbjct: 1062 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP-----PGPVGPSGKDGANG---IPG 1113 Query: 564 P-RPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSET 621 P P GP G P+ PG P P GP P P GP D A Sbjct: 1114 PIGPPGPRGRSGETGPAGPPGNPGPPGP--------------PGPPGPGIDMSAF----- 1154 Query: 622 PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKS 674 AG P E GP P R + A G DAEV+++ KS Sbjct: 1155 --------AGLGPREK-----GPDPLQYMRADQAAGG--LRQHDAEVDATLKS 1192 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.132 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,401,440 Number of Sequences: 37866 Number of extensions: 3052959 Number of successful extensions: 72272 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 906 Number of HSP's successfully gapped in prelim test: 2518 Number of HSP's that attempted gapping in prelim test: 18644 Number of HSP's gapped (non-prelim): 21759 length of query: 677 length of database: 18,247,518 effective HSP length: 109 effective length of query: 568 effective length of database: 14,120,124 effective search space: 8020230432 effective search space used: 8020230432 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.