Guide to the Human Genome
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Search of human proteins with 31542493

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542493 D site of albumin promoter (albumin D-box) binding
protein [Homo sapiens]
         (325 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542493 D site of albumin promoter (albumin D-box) binding p...   662   0.0  
gi|4504421 hepatic leukemia factor [Homo sapiens]                     248   5e-66
gi|223972670 thyrotrophic embryonic factor isoform 2 [Homo sapiens]   221   5e-58
gi|4507431 thyrotrophic embryonic factor isoform 1 [Homo sapiens]     221   5e-58
gi|239751641 PREDICTED: hypothetical protein XP_002347943 [Homo ...    66   4e-11
gi|52630429 nuclear factor, interleukin 3 regulated [Homo sapiens]     59   6e-09
gi|122937321 UNC homeobox [Homo sapiens]                               57   3e-08
gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]         56   4e-08
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               55   8e-08
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    54   1e-07
gi|50511941 EMI domain containing 1 [Homo sapiens]                     54   2e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    52   6e-07
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    52   7e-07
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    52   7e-07
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    52   7e-07
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    51   2e-06
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote...    51   2e-06
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi...    50   4e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   4e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    49   5e-06
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...    49   5e-06
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...    49   5e-06
gi|33286446 opioid growth factor receptor [Homo sapiens]               49   6e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   49   6e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   49   6e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   49   6e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    49   6e-06
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r...    49   6e-06
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                49   8e-06
gi|153791535 general control of amino acid synthesis 5-like 2 [H...    48   1e-05

>gi|31542493 D site of albumin promoter (albumin D-box) binding
           protein [Homo sapiens]
          Length = 325

 Score =  662 bits (1707), Expect = 0.0
 Identities = 325/325 (100%), Positives = 325/325 (100%)

Query: 1   MARPVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPA 60
           MARPVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPA
Sbjct: 1   MARPVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPA 60

Query: 61  ATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLD 120
           ATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLD
Sbjct: 61  ATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLD 120

Query: 121 AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASG 180
           AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASG
Sbjct: 121 AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASG 180

Query: 181 HRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPI 240
           HRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPI
Sbjct: 181 HRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPI 240

Query: 241 MKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQE 300
           MKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQE
Sbjct: 241 MKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQE 300

Query: 301 VVAVRQELSHYRAVLSRYQAQHGAL 325
           VVAVRQELSHYRAVLSRYQAQHGAL
Sbjct: 301 VVAVRQELSHYRAVLSRYQAQHGAL 325


>gi|4504421 hepatic leukemia factor [Homo sapiens]
          Length = 295

 Score =  248 bits (633), Expect = 5e-66
 Identities = 131/239 (54%), Positives = 171/239 (71%), Gaps = 9/239 (3%)

Query: 94  VPAPGLLAPLLWERTLPF-GD---VEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPA 149
           VP    L P LW++TLP+ GD   +EY+DL+ FL E+G+PPSP      SP P P   PA
Sbjct: 59  VPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDH-SPHP-PGLQPA 116

Query: 150 PSPGPGSCGSASPRSSPGHAPARAALGTASGHRAGL---TSRDTPSPVDPDTVEVLMTFE 206
            S  P     +S  S+P H    +     S  R G     +R+TPSP+DPDT++V + +E
Sbjct: 117 SSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYE 176

Query: 207 PDPADLALSSIPGHETFDPRRHRFSEEELKPQPIMKKARKIQVPEEQKDEKYWSRRYKNN 266
           PDPADLALSSIPG E FDPR+ +FSEEELKPQP++KKARK+ +P++ KD+KYW+RR KNN
Sbjct: 177 PDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNN 236

Query: 267 EAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGAL 325
            AAKRSRDARRLKENQI++RA+FLEKEN+ LRQEV  +R+EL   + +L++Y+A+HG L
Sbjct: 237 MAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL 295


>gi|223972670 thyrotrophic embryonic factor isoform 2 [Homo sapiens]
          Length = 273

 Score =  221 bits (564), Expect = 5e-58
 Identities = 118/232 (50%), Positives = 157/232 (67%), Gaps = 12/232 (5%)

Query: 100 LAPLLWERTLPFGD----VEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPG 155
           L P +W++T+P+      +EY+DLD FLLE+G+P SP         P        S    
Sbjct: 48  LMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAELEGKES---A 104

Query: 156 SCGSASPRSSPG--HAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLA 213
           S  +ASP SS      P+     T S        R+TPSP+DP+ VEV + F PDPADL 
Sbjct: 105 SSSTASPPSSSTAIFQPSETVSSTESSLEK---ERETPSPIDPNCVEVDVNFNPDPADLV 161

Query: 214 LSSIPGHETFDPRRHRFSEEELKPQPIMKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSR 273
           LSS+PG E F+PR+H+F+EE+LKPQP++KKA+K+ VP+EQKDEKYW+RR KNN AAKRSR
Sbjct: 162 LSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSR 221

Query: 274 DARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGAL 325
           DARRLKENQI++RAAFLEKEN  LR EV  +R+E+   + ++S+Y+ ++G L
Sbjct: 222 DARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYGPL 273


>gi|4507431 thyrotrophic embryonic factor isoform 1 [Homo sapiens]
          Length = 303

 Score =  221 bits (564), Expect = 5e-58
 Identities = 118/232 (50%), Positives = 157/232 (67%), Gaps = 12/232 (5%)

Query: 100 LAPLLWERTLPFGD----VEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPG 155
           L P +W++T+P+      +EY+DLD FLLE+G+P SP         P        S    
Sbjct: 78  LMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAELEGKES---A 134

Query: 156 SCGSASPRSSPG--HAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLA 213
           S  +ASP SS      P+     T S        R+TPSP+DP+ VEV + F PDPADL 
Sbjct: 135 SSSTASPPSSSTAIFQPSETVSSTESSLEK---ERETPSPIDPNCVEVDVNFNPDPADLV 191

Query: 214 LSSIPGHETFDPRRHRFSEEELKPQPIMKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSR 273
           LSS+PG E F+PR+H+F+EE+LKPQP++KKA+K+ VP+EQKDEKYW+RR KNN AAKRSR
Sbjct: 192 LSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSR 251

Query: 274 DARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGAL 325
           DARRLKENQI++RAAFLEKEN  LR EV  +R+E+   + ++S+Y+ ++G L
Sbjct: 252 DARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYGPL 303


>gi|239751641 PREDICTED: hypothetical protein XP_002347943 [Homo
           sapiens]
          Length = 369

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 34/67 (50%), Positives = 48/67 (71%), Gaps = 1/67 (1%)

Query: 239 PIMKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLR 298
           P +++ R+  +PEE+KD  YW +R KNNEAAKRSR+ RRL +  I  R A L +ENALL+
Sbjct: 61  PSIRRQREF-MPEEKKDTVYWEKRRKNNEAAKRSREKRRLNDAAIEGRLAALMEENALLK 119

Query: 299 QEVVAVR 305
            E+ A++
Sbjct: 120 GELKALK 126


>gi|52630429 nuclear factor, interleukin 3 regulated [Homo sapiens]
          Length = 462

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 26/57 (45%), Positives = 41/57 (71%)

Query: 249 VPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVR 305
           +P+E+KD  YW +R KNNEAAKRSR+ RRL +  +  +   L +ENA L+ E+++++
Sbjct: 67  IPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLK 123


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 45/127 (35%), Positives = 56/127 (44%), Gaps = 25/127 (19%)

Query: 59  PAATTPGPGLETAGPADAPAGAVVG-GGSP-----RGRPGPVPAPGLLAPLLWERTLPFG 112
           P    P P +  A PA A  GA  G GG+P     R  P  V +PG  AP       PF 
Sbjct: 406 PKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPA----PAPFR 461

Query: 113 DVEYVDLDAFLLEHG---------LPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPR 163
           D+      A   E G           P+PPPP  PSP P P R P+P+  P +CG   P 
Sbjct: 462 DLA----SAAATEGGGGDCADAGTAGPAPPPPA-PSPRPGP-RPPSPAEEPATCGVPEPG 515

Query: 164 SSPGHAP 170
           ++ G +P
Sbjct: 516 AAAGPSP 522



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 28/97 (28%), Positives = 35/97 (36%), Gaps = 18/97 (18%)

Query: 129 PPSPPPPG--GPSPEPSPARTPAPS-----PGPGSC---------GSASPRSSPGHAPAR 172
           PP PPPP   GP    S A   AP+     P PG+C           A P+  PG    +
Sbjct: 246 PPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADK 305

Query: 173 AALGTASGHRAGLTSRDTPS--PVDPDTVEVLMTFEP 207
            A     G       R         P +VE L++  P
Sbjct: 306 DAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSP 342



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 24/79 (30%), Positives = 31/79 (39%), Gaps = 7/79 (8%)

Query: 126 HGLPPSPPPPGGPSPEPSPARTPAP-SPGPGSCGSASPRSS---PGHAPARAALGTA--S 179
           H  P S    GG    P P   P P + GPG+  S +  ++   PG  PA      A   
Sbjct: 228 HSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYP 287

Query: 180 GHRAGLTSRDTPS-PVDPD 197
             R+G   +  P  P D D
Sbjct: 288 SQRSGAGPQPRPGRPADKD 306



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 36/120 (30%), Positives = 45/120 (37%), Gaps = 26/120 (21%)

Query: 54  RKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGD 113
           RKAA  AA     GL+ A         ++G G                 LL+  T P G 
Sbjct: 345 RKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHF---------------LLYPITQPLGF 389

Query: 114 VEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARA 173
           +    +    L+ G    P P   P   P+PA  PAP P   S G+    S PG AP  A
Sbjct: 390 L----VPQAALKGGAGLEPAPKDAP---PAPAVPPAP-PAQASFGAF---SGPGGAPDSA 438


>gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]
          Length = 345

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 78/303 (25%), Positives = 116/303 (38%), Gaps = 61/303 (20%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPG-- 98
           P+ PA  L    + + A+  +    P LE  G   APA A          P P PAP   
Sbjct: 56  PRPPAGELGSIGDHERAIDFS----PYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASS 111

Query: 99  -----LLAPLLWE--------RTLPFGDVEYVDLDA---------FLLEHGLPPSPPPPG 136
                 L+ L  +        +   +G V    L A         F   H  PP PPPP 
Sbjct: 112 GQHHDFLSDLFSDDYGGKNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPA 171

Query: 137 G----PSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALG---TASGHRAGLTSRD 189
                P  EP+  +    +  PG  G A   +   +A  RA LG     SG    L++  
Sbjct: 172 ELKAEPGFEPADCKRKEEAGAPG--GGAGMAAGFPYA-LRAYLGYQAVPSGSSGSLSTSS 228

Query: 190 TPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPIMKKARKIQV 249
           + SP  P T        P PAD             P    ++     P  +  KA+K   
Sbjct: 229 SSSP--PGT--------PSPADAKA----------PPTACYAGAAPAPSQVKSKAKKTV- 267

Query: 250 PEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVRQELS 309
             ++  ++Y  RR +NN A ++SRD  +++  +   +   L  EN  L+++V  + +ELS
Sbjct: 268 --DKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELS 325

Query: 310 HYR 312
             R
Sbjct: 326 TLR 328



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 30/105 (28%), Positives = 39/105 (37%), Gaps = 11/105 (10%)

Query: 128 LPPSPPPPGGPSPEPS----PARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRA 183
           LP  PPPP   S E +     A   A + G  +  +A P + PG  P    LG+   H  
Sbjct: 12  LPLPPPPPAFKSMEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPAGELGSIGDHER 71

Query: 184 GLT----SRDTPSPVDPDTVEVLMTFE---PDPADLALSSIPGHE 221
            +          +P  P       TFE   P PA    SS   H+
Sbjct: 72  AIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHD 116


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 55/190 (28%), Positives = 69/190 (36%), Gaps = 32/190 (16%)

Query: 11  APLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEK------ERKAALPAATTP 64
           APL+    A  P  G +         G     EP  C L +         +  +PAA +P
Sbjct: 44  APLVPAASASAPQRGPS---------GILPAAEPTICSLHQAWGGPGCRAQKGIPAALSP 94

Query: 65  GPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLL 124
           GPG     PA  P  A + G  P   PGP+P P  + P      +P      V +     
Sbjct: 95  GPG---PIPAPIPGPAQIPGPLPGSIPGPIPGPAQI-PSPIPAPIPGPISGPVQIPGPFR 150

Query: 125 EHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRAG 184
                P P P  GP+P P P   P   P PG      P  +PG  P     G  SG   G
Sbjct: 151 G----PIPGPISGPAPIPGPISGPFSGPNPGPI----PGPNPGPIP-----GPISGPIPG 197

Query: 185 LTSRDTPSPV 194
             S   P P+
Sbjct: 198 PISVPIPGPI 207



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 52/228 (22%), Positives = 74/228 (32%), Gaps = 57/228 (25%)

Query: 64  PGP-GLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAF 122
           PGP  +   GP   P    + G +P   PGP+P P                         
Sbjct: 196 PGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGP------------------------- 230

Query: 123 LLEHGLPPSPPPPGGPSPE--------------------PSPARTPAPS--PGPGSCGSA 160
           +      P P P  GP+P                     PSPA+ P P    GPG   S 
Sbjct: 231 ISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSP 290

Query: 161 SPRSSPGHAPARA-ALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPG 219
               SPG  P  A  LG  SG  +G      P P        L    PD +D     +P 
Sbjct: 291 GRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDASDF----LPD 346

Query: 220 HETFDPRRHRFSEEELKPQPIMKKARKIQVPEEQKDEKYWSRRYKNNE 267
            + F      F+E  L   P+   +      + Q+ +    +++  ++
Sbjct: 347 TQLFP----HFTELLLPLDPLEGSSVSTMTSQYQEGDDSMGKKHSGSQ 390



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 39/134 (29%), Positives = 47/134 (35%), Gaps = 31/134 (23%)

Query: 64  PGPGLETA---GPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLD 120
           PGP    A   GP   P      G  P   PGP+P P +  P+    ++P          
Sbjct: 154 PGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGP-ISGPIPGPISVPIPG------- 205

Query: 121 AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASG 180
                    P P P  GP   P+P   P P PGP S        +PG  P     G  SG
Sbjct: 206 ---------PIPGPISGPISGPNPGPIPGPIPGPIS------GPNPGPIP-----GPISG 245

Query: 181 HRAGLTSRDTPSPV 194
              GL     P P+
Sbjct: 246 PNPGLIPGPIPGPI 259


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/108 (33%), Positives = 39/108 (36%), Gaps = 33/108 (30%)

Query: 83  GGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEP 142
           GGG P   PG  PAPG                              PP PPPP  P  +P
Sbjct: 6   GGGRPGESPGATPAPG------------------------------PPPPPPPAPPQQQP 35

Query: 143 SPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRAGLTSRDT 190
            P   PAP PGPG      P  +    P  A  G   G R  L SRD+
Sbjct: 36  PPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEG---GPRGRLRSRDS 80



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 38/119 (31%), Positives = 45/119 (37%), Gaps = 18/119 (15%)

Query: 64  PGPGLETAGPAD----APAGAVVGGGSPRGRP-GPVPAPGLLAPLLWERTLPFGDVEYVD 118
           PGP    A P      +P GA     +PR  P G +PA  L  P L  R L       + 
Sbjct: 763 PGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRAS-RPLS 821

Query: 119 LDAFLLEHGLP---PSPPPPGGPSPEPSP---ARTPAPSP------GPGSCGSASPRSS 165
                L HG P    S  P    +P   P   AR  APSP       PG+ G   P+ S
Sbjct: 822 ASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGLDPQDS 880



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 46/162 (28%), Positives = 51/162 (31%), Gaps = 58/162 (35%)

Query: 85  GSPR--GRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEP 142
           GSPR   RP P PAP   +P                        G PP   PPG P+   
Sbjct: 753 GSPRLVRRPPPGPAPAAASP------------------------GPPPPASPPGAPASPR 788

Query: 143 SPARTP------APSPGPGSCG----------SASPRSSPGHAPARAA-----------L 175
           +P  +P      AP  GP              SAS  S P  AP  AA           L
Sbjct: 789 APRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRL 848

Query: 176 GTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSI 217
           G     RA   S D      P     L     DP D A S +
Sbjct: 849 GPTPAARAAAPSPDRRDSASPGAAGGL-----DPQDSARSRL 885



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 39/139 (28%), Positives = 48/139 (34%), Gaps = 26/139 (18%)

Query: 63  TPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAP-------GLLAPLLWERTLPFGDVE 115
           TP PG     P   P         P   PGP PAP         L P   +   P G + 
Sbjct: 17  TPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRLR 76

Query: 116 YVDLDAFLLEHGLPPSP----PPPGGPS-------PEPSPARTPAPSPGPG---SCGSAS 161
             D        G P +P       G P+       P+ SPA    P+ GP    SC  A+
Sbjct: 77  SRDSSC-----GRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAA 131

Query: 162 PRSSPGHAPARAALGTASG 180
              +PG  PA  A    +G
Sbjct: 132 SGPAPGPGPAEEAGSEEAG 150


>gi|50511941 EMI domain containing 1 [Homo sapiens]
          Length = 443

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 56/201 (27%), Positives = 65/201 (32%), Gaps = 18/201 (8%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSL--LQGTSKPKEPASCLLKEKERKAALPAA 61
           P +   PAPL    PA   PG G L        L G + PK  A         +  +   
Sbjct: 170 PATPEDPAPLWGPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGS-------RGPMGMR 222

Query: 62  TTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPL--LWERTLPFGDVEYVDL 119
             PGP      P  A A    G   P G PGP   PG  AP+     R    GD    + 
Sbjct: 223 GPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNT 282

Query: 120 DAFLLEHGL-----PPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAA 174
                 H       PP PP P GP   P P   P      G  G   P+   GH   +  
Sbjct: 283 FTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGE 342

Query: 175 LGTAS--GHRAGLTSRDTPSP 193
            G     G +     R  P P
Sbjct: 343 RGLRGEPGPQGSAGQRGEPGP 363



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 27/100 (27%), Positives = 35/100 (35%), Gaps = 26/100 (26%)

Query: 123 LLEHGLPPSPPPPGGPSP--EPSPAR----------------TPAPSPGPGSCGSASP-- 162
           ++E  +PP+P  P  P+P   P PA+                 P P+   G  GS  P  
Sbjct: 161 VIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMG 220

Query: 163 -RSSPG-----HAPARAALGTASGHRAGLTSRDTPSPVDP 196
            R  PG      +P RA      G R        P P  P
Sbjct: 221 MRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGP 260


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 56/194 (28%), Positives = 72/194 (37%), Gaps = 37/194 (19%)

Query: 64  PGPGLETAGPADA---PAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLD 120
           P PG+ +A PA +   PA     G  P   PGP P P    P +   + P G        
Sbjct: 117 PAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP---PPAV--TSAPPGAPPPTPPS 171

Query: 121 AFLLEHGLPPSPPPPGGPSPEPS--PARTPAPSPGPGSCGSASPRSSPGHAPARA-ALGT 177
           +     G+P +PP  GGP P P+  P   P P  GPG  G    +   G  P     L T
Sbjct: 172 S-----GVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLST 226

Query: 178 ASG-----HRAGLTSR--------------DTPSPVDPD--TVEVLMTFEPDPADLALSS 216
             G     HR G   R                P P  P   + E +   E   A+L+L  
Sbjct: 227 PGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLR 286

Query: 217 IPGHETFDPRRHRF 230
            PG +T+  R   F
Sbjct: 287 RPGEKTYTQRCRLF 300



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 26/90 (28%), Positives = 29/90 (32%), Gaps = 9/90 (10%)

Query: 129 PPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRAGLT-- 186
           PP  PPP  P P P P +   P P P           PG AP   +   AS      T  
Sbjct: 78  PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPP 137

Query: 187 -------SRDTPSPVDPDTVEVLMTFEPDP 209
                  S   P+P  P  V       P P
Sbjct: 138 TSGAPPGSGPGPTPTPPPAVTSAPPGAPPP 167



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 22/79 (27%), Positives = 27/79 (34%), Gaps = 8/79 (10%)

Query: 128 LPPSPP-------PPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARA-ALGTAS 179
           +PP PP       PP  P P+  P   P P P P       P       P  A   G A 
Sbjct: 60  IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP 119

Query: 180 GHRAGLTSRDTPSPVDPDT 198
           G  +   +  +  P  P T
Sbjct: 120 GVGSAPPASSSAPPATPPT 138



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 22/92 (23%), Positives = 30/92 (32%), Gaps = 11/92 (11%)

Query: 9   TPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKE-----------RKAA 57
           TP P +   P G PP      G+ +       P  P + +                +   
Sbjct: 152 TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGK 211

Query: 58  LPAATTPGPGLETAGPADAPAGAVVGGGSPRG 89
           +P    PG G   + P   P     GGG PRG
Sbjct: 212 MPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRG 243


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 42/145 (28%), Positives = 55/145 (37%), Gaps = 28/145 (19%)

Query: 39  SKPKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPG 98
           S P EPA+      E    L  A    P +    PA  P    V   +P   P PV AP 
Sbjct: 105 SPPLEPAA------ESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAP- 157

Query: 99  LLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCG 158
           + AP+                        L P+P P   P+P P+P   PAP+P P    
Sbjct: 158 VAAPVAVAV--------------------LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP 197

Query: 159 SASPRSSPGHAPARAA-LGTASGHR 182
           + +P  +P  AP  +A  G   G R
Sbjct: 198 APAPAPAPDAAPQESAEQGANQGQR 222



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 45/192 (23%), Positives = 61/192 (31%), Gaps = 27/192 (14%)

Query: 10  PAPLLLGGPAGTP--PGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPG 67
           P P+ +      P  P   +L GL    +       PA           A   A  P P 
Sbjct: 95  PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP- 153

Query: 68  LETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHG 127
              A P  AP    V   +P   P P PAP   AP+      P                 
Sbjct: 154 --VAAPVAAPVAVAVLAPAPAPAPAPAPAP---APVAAPAPAP----------------A 192

Query: 128 LPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHA--PARAALGTASGHRAGL 185
             P+P P   P+P+ +P  +       G  G   P +   H+    R A GTA+    G 
Sbjct: 193 PAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAAASANGA 251

Query: 186 TSRDTPSPVDPD 197
             +    P+  D
Sbjct: 252 AIKKLSGPLISD 263


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 42/145 (28%), Positives = 55/145 (37%), Gaps = 28/145 (19%)

Query: 39  SKPKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPG 98
           S P EPA+      E    L  A    P +    PA  P    V   +P   P PV AP 
Sbjct: 105 SPPLEPAA------ESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAP- 157

Query: 99  LLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCG 158
           + AP+                        L P+P P   P+P P+P   PAP+P P    
Sbjct: 158 VAAPVAVAV--------------------LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP 197

Query: 159 SASPRSSPGHAPARAA-LGTASGHR 182
           + +P  +P  AP  +A  G   G R
Sbjct: 198 APAPAPAPDAAPQESAEQGANQGQR 222



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 45/192 (23%), Positives = 61/192 (31%), Gaps = 27/192 (14%)

Query: 10  PAPLLLGGPAGTP--PGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPG 67
           P P+ +      P  P   +L GL    +       PA           A   A  P P 
Sbjct: 95  PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP- 153

Query: 68  LETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHG 127
              A P  AP    V   +P   P P PAP   AP+      P                 
Sbjct: 154 --VAAPVAAPVAVAVLAPAPAPAPAPAPAP---APVAAPAPAP----------------A 192

Query: 128 LPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHA--PARAALGTASGHRAGL 185
             P+P P   P+P+ +P  +       G  G   P +   H+    R A GTA+    G 
Sbjct: 193 PAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAAASANGA 251

Query: 186 TSRDTPSPVDPD 197
             +    P+  D
Sbjct: 252 AIKKLSGPLISD 263


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 42/145 (28%), Positives = 55/145 (37%), Gaps = 28/145 (19%)

Query: 39  SKPKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPG 98
           S P EPA+      E    L  A    P +    PA  P    V   +P   P PV AP 
Sbjct: 116 SPPLEPAA------ESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAP- 168

Query: 99  LLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCG 158
           + AP+                        L P+P P   P+P P+P   PAP+P P    
Sbjct: 169 VAAPVAVAV--------------------LAPAPAPAPAPAPAPAPVAAPAPAPAPAPAP 208

Query: 159 SASPRSSPGHAPARAA-LGTASGHR 182
           + +P  +P  AP  +A  G   G R
Sbjct: 209 APAPAPAPDAAPQESAEQGANQGQR 233



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 45/192 (23%), Positives = 61/192 (31%), Gaps = 27/192 (14%)

Query: 10  PAPLLLGGPAGTP--PGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPG 67
           P P+ +      P  P   +L GL    +       PA           A   A  P P 
Sbjct: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP- 164

Query: 68  LETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHG 127
              A P  AP    V   +P   P P PAP   AP+      P                 
Sbjct: 165 --VAAPVAAPVAVAVLAPAPAPAPAPAPAP---APVAAPAPAP----------------A 203

Query: 128 LPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHA--PARAALGTASGHRAGL 185
             P+P P   P+P+ +P  +       G  G   P +   H+    R A GTA+    G 
Sbjct: 204 PAPAPAPAPAPAPDAAPQESAEQGANQGQRGQ-EPLADQLHSGISGRPAAGTAAASANGA 262

Query: 186 TSRDTPSPVDPD 197
             +    P+  D
Sbjct: 263 AIKKLSGPLISD 274


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 73/258 (28%), Positives = 88/258 (34%), Gaps = 55/258 (21%)

Query: 2   ARPVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAA 61
           A P  DR P P    GP G PP   A         G + P+ P              P  
Sbjct: 210 AVPGGDRFPGP---AGPGGPPPPFPA---------GQTPPRPPLGPPGPPGPPGPPPPGQ 257

Query: 62  TTPGPGLETAGPADAPAGAVVGGGSPRGRP--GPVPAPGLLAPLLWERTLPFGDVEYVDL 119
             P P        D P   V+  G P G+P  GP+P PG   P+                
Sbjct: 258 VLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP-PGPPPPVPG-------------- 302

Query: 120 DAFLLEHGLPPSPPPPG-GPSPEPS--PARTPAPSPGPGSCGSAS--PRSSPGHAPARAA 174
                 +G PP PPPP  GP P P   P R P P   P +       P   PG  P    
Sbjct: 303 ------YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPH 356

Query: 175 LGTA---SGHRAGLTSRDT--PSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHR 229
           +  A       +G+ + D+  P P DP          P P D      PG E  D  R  
Sbjct: 357 VNPAFFPPPTNSGMPTSDSRGPPPTDP-------YGRPPPYDRGDYGPPGRE-MDTARTP 408

Query: 230 FSEEELKPQPIMKKARKI 247
            SE E   + IM + R I
Sbjct: 409 LSEAEF--EEIMNRNRAI 424


>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
           1 [Homo sapiens]
          Length = 828

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 68/257 (26%), Positives = 93/257 (36%), Gaps = 27/257 (10%)

Query: 59  PAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAP-GLLAPLLWERTLP------F 111
           P      P      PAD+PA   +G   P G PGP   P  +L+PL  E          F
Sbjct: 329 PREKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTF 388

Query: 112 GDVEYVDLDAFLLEHGL-----PPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSP 166
              +Y++  +   + GL     PP PPPP   +   SP   P   PGPG+   AS  + P
Sbjct: 389 IKDDYLETISSPKDFGLGQRATPPPPPPPTYRTVVSSPG--PGSGPGPGTTSGASSPARP 446

Query: 167 GH--APARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFD 224
                P R+        R    SR    P  P   +V   F P    +  SS P      
Sbjct: 447 ATPLVPCRSTTPPPPPPRP--PSRPKLPPGKPGVGDVSRPFSP---PIHSSSPP---PIA 498

Query: 225 PRRHRFSEEELKPQPIMKKARKIQVPEEQKDEKYWSRR--YKNNEAAKRSRDARRL-KEN 281
           P     S   +     +  A    V  EQ    ++ R   Y   E + R      +  ++
Sbjct: 499 PLARAESTSSISSTNSLSAATTPTVENEQPSLVWFDRGKFYLTFEGSSRGPSPLTMGAQD 558

Query: 282 QISVRAAFLEKENALLR 298
            + V AAF E  NA  +
Sbjct: 559 TLPVAAAFTETVNAYFK 575



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 38/145 (26%), Positives = 50/145 (34%), Gaps = 39/145 (26%)

Query: 92  GPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPP------PPGGPSPEPSPA 145
           GPV +P  +A    E+ + F D           EH  P   P      PP  P    +PA
Sbjct: 296 GPVLSPKSVAVNAEEKWVHFSDTSP--------EHVTPELTPREKVVSPPATPD---NPA 344

Query: 146 RTPAPSP--GPGSCGSASPRSSPGHAPARAAL-------------------GTASGHRAG 184
            +PAP P   PG  G   P   P +  +   L                     +S    G
Sbjct: 345 DSPAPGPLGPPGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFG 404

Query: 185 LTSRDTPSPVDPDTVEVLMTFEPDP 209
           L  R TP P  P T   +++  P P
Sbjct: 405 LGQRATPPPPPPPTYRTVVS-SPGP 428


>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 547

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 64/213 (30%), Positives = 82/213 (38%), Gaps = 19/213 (8%)

Query: 16  GGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPGL-ETAGPA 74
           G  A  PP G  L G  SL   T +P        K    KAA+P A      L   +GP 
Sbjct: 327 GSAAPGPPRGPRLQGGGSL---TLQPDYAKYATFKAAALKAAVPRARRSANRLPRPSGPR 383

Query: 75  DAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPP 134
             PA A     SP G P PV + G    +     +P    E    D       L PSP  
Sbjct: 384 PRPAPARSPSQSPAGTPCPVLSLGARRGVTLPCPVP---AEAAPRDFCQRFPALEPSPRQ 440

Query: 135 PGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSPV 194
           P        PAR P PSP   +   A P + P +AP  AA G  +   +   +R  P+P+
Sbjct: 441 P--------PARAPRPSPDLPAPLDACPWAPPVYAPP-AAPGPYAAWTSSRPAR--PAPL 489

Query: 195 DPDTVEVL-MTFEPDPADLALSSIPGHETFDPR 226
              T     +   P  A     S+   ETF+P+
Sbjct: 490 SHPTARAFQVPRRPGHAARRQFSVKMPETFNPQ 522



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/134 (27%), Positives = 48/134 (35%), Gaps = 24/134 (17%)

Query: 86  SPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSP------PPPGGPS 139
           +PRG   P P  G         TL     +Y    A  L+  +P +       P P GP 
Sbjct: 324 APRGSAAPGPPRGPRLQGGGSLTLQPDYAKYATFKAAALKAAVPRARRSANRLPRPSGPR 383

Query: 140 PEPSPARTPAPSPGPGSC------------------GSASPRSSPGHAPARAALGTASGH 181
           P P+PAR+P+ SP    C                    A+PR      PA          
Sbjct: 384 PRPAPARSPSQSPAGTPCPVLSLGARRGVTLPCPVPAEAAPRDFCQRFPALEPSPRQPPA 443

Query: 182 RAGLTSRDTPSPVD 195
           RA   S D P+P+D
Sbjct: 444 RAPRPSPDLPAPLD 457



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 51/196 (26%), Positives = 64/196 (32%), Gaps = 24/196 (12%)

Query: 64  PGPGLETAGPADAPAGAVV----GGGSPRGRPGPVPAPGLLAPLLWERTLP---FGDVEY 116
           PGP          P G  V    G G PRG P     P    P L   + P   F  V  
Sbjct: 186 PGPQEPLPPTLGPPLGGCVQVQMGDGLPRGSPHNSAGPR--TPRLARASPPGEPFMRVAP 243

Query: 117 VDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPG-PGSCGSASPRS----------S 165
             L A        P P P  G   E      P P  G PGS  +AS R           +
Sbjct: 244 PGLAAAAAARDSEPGPVPGAGGCGEDRLGSQPRPENGPPGSHRTASGRGLRRGDSEGGVN 303

Query: 166 PGHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEV----LMTFEPDPADLALSSIPGHE 221
            G  P+R +L      R     R + +P  P    +     +T +PD A  A       +
Sbjct: 304 RGIGPSRVSLLAPDKKRLNNAPRGSAAPGPPRGPRLQGGGSLTLQPDYAKYATFKAAALK 363

Query: 222 TFDPRRHRFSEEELKP 237
              PR  R +    +P
Sbjct: 364 AAVPRARRSANRLPRP 379


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 63/232 (27%), Positives = 76/232 (32%), Gaps = 22/232 (9%)

Query: 2    ARPVSDRTPAPLLLGGPAGTPP---GGGALLGLR-SLLQGTSKPKEPASCLLKEKERKAA 57
            A P     P P     PA TPP   GG A    + +     + P  P         + A 
Sbjct: 932  ASPSPKGAPTP-----PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986

Query: 58   LP-AATTPGP--GLETAGPADAPAGAVVGGGSPRGRPGPVPAP-GLLAPLLWERTLPFGD 113
             P AAT P P  G  T  P  AP    V   SP+G P   P P G   P       P G 
Sbjct: 987  TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046

Query: 114  VEYVDLDAFLLEHGLPPSPPPPGGPS-------PEPSPARTPAPSPGPGSCGSASPRSSP 166
                 L            P P GGP+       P P  A  P+P  GP +         P
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106

Query: 167  GHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIP 218
               P     G A+    G  +  TP+   P     L T  P  A    ++ P
Sbjct: 1107 AATPPSPKGGLATPPHKGAPT--TPAATPPSPKGGLATPPPKGAPTTPAATP 1156



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 58/201 (28%), Positives = 66/201 (32%), Gaps = 25/201 (12%)

Query: 4    PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
            P +     P   GGPA  PP G             + P      L     + A  PA  T
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPT-------PPAATPPSLKGGLATPPHKGAPNPAVVT 1293

Query: 64   PGP---GLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLD 120
            P     G  T+ P  AP        SP+G PG  P  G   P       P G        
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353

Query: 121  AFLLEHGLPPS----PPPP-------GGPS-PEPSPARTPA-PSPGPGSCGSASPRSSPG 167
                     PS    P PP       GGP+   PSP R PA PSP       A    SP 
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413

Query: 168  HAPARAAL--GTASGHRAGLT 186
             APA      G A+  +  LT
Sbjct: 1414 KAPATPVTREGAATPSKGDLT 1434



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 59/202 (29%), Positives = 77/202 (38%), Gaps = 27/202 (13%)

Query: 5   VSDRTPAPLLLGGPAG--TPPGG---------GALLGLRSL-LQGTSKPKEPASCLLKEK 52
           VS +T  P    G AG  TP G           + L   SL  QG+              
Sbjct: 801 VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860

Query: 53  ERKAALPAATTP-GPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPF 111
            + A  P+A TP  P   T  P + P  +VV    P+  P   PAP     L    + P 
Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA-TPAPKQAPALSMTSSSP- 918

Query: 112 GDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPA 171
                    A     G+P SP P G P+P   PA TP PSP  G   + SP+ +P   P 
Sbjct: 919 -----KKARATPAPKGIPASPSPKGAPTP---PAATP-PSP-KGGPATPSPKWAP--TPP 966

Query: 172 RAALGTASGHRAGLTSRDTPSP 193
            A   +  G  A  + +  P+P
Sbjct: 967 AATPPSPKGGPATPSPKGAPTP 988



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 63/192 (32%), Positives = 71/192 (36%), Gaps = 29/192 (15%)

Query: 18   PAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAAL--------PAATTPGP--G 67
            PA TPP          L +G   P  PA+ L   K   A          PAAT P P  G
Sbjct: 1036 PAATPPSPKGSPAATPLPKGA--PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093

Query: 68   LETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPF---GDVEYVDLDAFLL 124
              T  P  AP        SP+G     P  G  AP     T P    G        A   
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKG--APTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 125  EHGLPPSPPPPGG---PSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGH 181
                PPSP   GG   P P+ +P  TPA +P     G A+P  SP  AP   A  T    
Sbjct: 1152 PAATPPSPK--GGLATPPPKGAPT-TPAATPPSPKGGLATP--SPKGAPTTPA-ATPPSP 1205

Query: 182  RAGLTSRDTPSP 193
            + GL    TPSP
Sbjct: 1206 KGGLA---TPSP 1214



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 57/198 (28%), Positives = 68/198 (34%), Gaps = 19/198 (9%)

Query: 4    PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKA-ALPAAT 62
            P +     P   GG A  PP G             + P  P   L     + A   PAAT
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTP-------AATPPSPKGGLATPPPKGAPTTPAAT 1178

Query: 63   TPGP--GLETAGPADAPAGAVVGGGSPRG---RPGPVPAPGLLAPLLWERTLPFGDVEYV 117
             P P  GL T  P  AP        SP+G    P P  AP    P     +   G     
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP--TTPAATPPSPKGGLATPS 1236

Query: 118  DLDAFLLEHGLPPSPPPPGGP-SPEPSPART-PAPSPGPGSCGSASPRSSPGHAPARAAL 175
               A       PPSP   GGP +P P  A T PA +P     G A+P       PA    
Sbjct: 1237 PKGAPTTPAATPPSPK--GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 176  GTASGHRAGLTSRDTPSP 193
             +  G  A    +  P+P
Sbjct: 1295 PSPKGGPATSPPKGAPTP 1312



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 57/199 (28%), Positives = 72/199 (36%), Gaps = 25/199 (12%)

Query: 18   PAGTPP---GGGALLGLRSL-LQGTSKPKEPASCLLKEKERKA-ALPAATTPGP--GLET 70
            PA TPP   GG A    +       + P  P   L     + A   PAAT P P  GL T
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234

Query: 71   AGPADAPAGAVVGGGSPRGRPGPVPAPGL-LAPLLWERTLPFGDVEYVDLDAFLLEHGLP 129
              P  AP        SP+G P   P  G    P     +L  G        A       P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 130  PSPP-------------PPGG--PSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAA 174
            PSP              PP    PSP+ SP  TP P   P +  + +P S  G     A 
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPG-TPPPKGAP-TPPAVTPPSPKGTPTLPAT 1352

Query: 175  LGTASGHRAGLTSRDTPSP 193
              ++ G     +S++ P+P
Sbjct: 1353 TPSSKGGPTTPSSKEGPTP 1371



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 53/215 (24%), Positives = 75/215 (34%), Gaps = 22/215 (10%)

Query: 41   PKEPASCLLKEKER-----KAAL--PAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGP 93
            P  P + LL +K       K AL  PA T P P    A P    A A          P  
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585

Query: 94   VPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGG--PSPEPSPARTPAPS 151
             P+    AP   E  +P         +A          P PP    PSPE  PA TPAP 
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEA----------PTPPAVTPPSPEKGPA-TPAPK 1634

Query: 152  PGPGSCGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPAD 211
              P S    +P S      + A++    G      S+  P+   P  ++ ++   P P  
Sbjct: 1635 GTPTS-PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLV-APAPES 1692

Query: 212  LALSSIPGHETFDPRRHRFSEEELKPQPIMKKARK 246
              + + P  +    ++   +   + P P  K   K
Sbjct: 1693 TPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 64/224 (28%), Positives = 90/224 (40%), Gaps = 53/224 (23%)

Query: 1   MARPVSDRTPAPLLLGGPAGTPPGGGALLGL---RSLLQGTSKPKEPASCLLKEKERKAA 57
           +A  +    P+P L   PAGTPPG   + G+    +L    S PKE  +      E   A
Sbjct: 726 LAPEIPKSVPSPSL--PPAGTPPGTKKVDGISHTSALAPVASSPKECPT------EDSGA 777

Query: 58  LPAATTPGPGLETAGPADAPAGAVVGGGSPR-----GRPGP-VPAPGLLAPL-------L 104
              A++ G  L     + +P G  V   + R     G  GP  P   L +P+       L
Sbjct: 778 SATASSKGT-LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL 836

Query: 105 WERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEP-----------SPARTPAPS-- 151
            E +L F   +    D+    H  P  P P G P+P              P  TP PS  
Sbjct: 837 PENSLSFQGSK----DSPATTHS-PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891

Query: 152 --PGPGSCGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSP 193
             P P   G A+P  +P  APA  ++ ++S  +A    R TP+P
Sbjct: 892 NLPFPKE-GPATP--APKQAPA-LSMTSSSPKKA----RATPAP 927



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 54/198 (27%), Positives = 65/198 (32%), Gaps = 14/198 (7%)

Query: 59   PAATTPGP--GLETAGPADAPAGAVVGGGSPRGRPG-PVPAPGLLAPLLWERTLP-FGDV 114
            PA T P P  G     P   P    V   SP+  P  PV   G   P   + T P    V
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441

Query: 115  EYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAA 174
                  A     G P +P   G P+    PA TP     P +    +  SSP  APA  A
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPT---LPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498

Query: 175  LGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEE 234
               A    A + S     P  P +       +P      L S     T  P+        
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRR-----DPIAPTATLLSKKTPATLAPKEALIPPAM 1553

Query: 235  LKPQPIMKKARKIQVPEE 252
              P P  KK   I  P+E
Sbjct: 1554 TVPSP--KKTPAIPTPKE 1569



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 36/144 (25%), Positives = 49/144 (34%), Gaps = 12/144 (8%)

Query: 59   PAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVD 118
            PA T+P P      PA  P     G  +P  +  P   P   + L    T P      + 
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG 1662

Query: 119  LDAFLLEHGLPPSPPPPG------GPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPAR 172
                    GLP    P         P+PE +P  T     GP +    S  +SP   P  
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT--KKSSATSPPICPDP 1720

Query: 173  AALGTASGHRAGLTSRDTPSPVDP 196
            +A   + G      S   P+P+ P
Sbjct: 1721 SAKNGSKGP----LSTVAPAPLLP 1740



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 11/57 (19%)

Query: 130 PSPPPPGGPSPEPSP---ARTPAPSPGPGSCGSAS-----PRSSPGHAPARAALGTA 178
           P+ PPP  P+P+  P   A   +P P P +  S       P+SS G A     LGTA
Sbjct: 43  PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTA---LPLGTA 96



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 56/212 (26%), Positives = 70/212 (33%), Gaps = 34/212 (16%)

Query: 9    TPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPGL 68
            TP  L        P GG A    +        P  PA      KE  A    AT+  P  
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKG------DPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492

Query: 69   ETAGPAD--APAGAVVGGGSPRGRPG-PVPAPGLLAP---LLWERTLPFGDVEYVDLDAF 122
              A PA   AP    V   SP+  P  P      +AP   LL ++T           +A 
Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT----PATLAPKEAL 1548

Query: 123  LLEHGLPPSPPP-PGGPSPEPSPAR------------TP-----APSPGPGSCGSASPRS 164
            +      PSP   P  P+P+ +PA             TP     APSP       A    
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608

Query: 165  SPGHAPARAALGTASGHRAGLTSRDTPSPVDP 196
            SP  AP   A+   S  +   T     +P  P
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 62/239 (25%), Positives = 84/239 (35%), Gaps = 35/239 (14%)

Query: 8   RTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPA-ATTPGP 66
           R P     G  A  P       G      G +KP  PA+   +        P     PGP
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186

Query: 67  GLETAGP-----------------ADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTL 109
           G + AGP                 A APA ++V  G     P P PA    AP    +T 
Sbjct: 187 G-KPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA----APGTVIQTP 241

Query: 110 PFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHA 169
           PF                 P +P PP  P+P  +PA  P P P P     A P   P   
Sbjct: 242 PFVGAAAPPA---------PAAPSPPAAPAPA-APAAAPPPPP-PAPATLARPPGHPAGP 290

Query: 170 PARA-ALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRR 227
           P  A A+   +  + G ++   P+P         ++ +P P   A +  PG +   P+R
Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKR 349



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 46/143 (32%), Positives = 50/143 (34%), Gaps = 12/143 (8%)

Query: 59  PAATTPGPGLETAGPADAPAG-AVVGGGSPRGRPGPVPAP-------GLLAPLLWERTLP 110
           PAA  P  G   A P   PAG A  GGG P+ RPGP P+P       G   P    R  P
Sbjct: 75  PAA--PAEGAPGAAPEPPPAGRARPGGGGPQ-RPGP-PSPRRPLVPAGPAPPAAKLRPPP 130

Query: 111 FGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAP 170
            G                 P P P G   P    A      PGPG      P   PG   
Sbjct: 131 EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190

Query: 171 ARAALGTASGHRAGLTSRDTPSP 193
              A  T +G  A L S    +P
Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAP 213



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 64/237 (27%), Positives = 81/237 (34%), Gaps = 34/237 (14%)

Query: 10  PAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALP---AATTPGP 66
           PAP     PA   P   A             P  PA   L       A P   A   P P
Sbjct: 250 PAPAAPSPPAAPAPAAPA---------AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300

Query: 67  GLE----TAGPADAPAGAVVGGGSPRGRPGP-----VPAPGLLAPLLWERTLPFGDVEYV 117
                  +AG A APA A  G     G+PGP      PAPG+ A        P   V+  
Sbjct: 301 AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES------PKRVVQAA 354

Query: 118 DLDAFLLEHGLPPSPPPPG--GPSPE---PSPARTPAPSPGPGSCGSASPRSSPGHAPAR 172
              A  L    P S       GP+ +   PSPA  P P+PG  +        +   + +R
Sbjct: 355 PPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR 414

Query: 173 AALGTASGHRAGLTSRDTPS--PVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRR 227
               T SG RA LT        P  P     +  F+  P  + + S  G     P++
Sbjct: 415 TPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQ 471



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 12/98 (12%)

Query: 127 GLPPSPPPPGGP--SPEPSPARTPAPSPG----PGSCGSASPRSSPGHAPARAALGTASG 180
           G  P+ P  G P  +PEP PA    P  G    PG      P    G AP  A L     
Sbjct: 72  GAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPE 131

Query: 181 HRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIP 218
             AG     + +PV P    V    EP PA  A  + P
Sbjct: 132 GSAG-----SCAPV-PAAAAVAAGPEPAPAGPAKPAGP 163


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 51/199 (25%), Positives = 67/199 (33%), Gaps = 21/199 (10%)

Query: 41   PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAV--------VGGGSPRGRPG 92
            P  P SC   +       P     GPG +        +GA+        +G   P+G PG
Sbjct: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628

Query: 93   PVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEP--------SP 144
            P    GL  P    R    GD     L       GLP  P P G P             P
Sbjct: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688

Query: 145  ARTPAPSPGPGSCGSASPRSSPGH-----APARAALGTASGHRAGLTSRDTPSPVDPDTV 199
               P P   PGS G   P   PG       P  + L    G R  + S++    V     
Sbjct: 1689 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 1748

Query: 200  EVLMTFEPDPADLALSSIP 218
            E L++ + +  +  L+ IP
Sbjct: 1749 EQLISGQMNRFNQMLNQIP 1767



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/110 (33%), Positives = 41/110 (37%), Gaps = 12/110 (10%)

Query: 64   PGPGLETAGPADAPAGAVVGGG-SPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAF 122
            PGP     GP   P  A   G   P GRPG    PG+  P   ER LP    E     + 
Sbjct: 1777 PGP----PGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP-GERGLPGEKGERGTGSSG 1831

Query: 123  LLEHGLPPSPPPPG----GPSPEPSPARTPAPSPGPGSCGSASPRSSPGH 168
                GLP  P P G    GP         P P   PG+ G   P   PG+
Sbjct: 1832 --PRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 24/68 (35%), Positives = 24/68 (35%), Gaps = 8/68 (11%)

Query: 129  PPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRAGLTSR 188
            PP PP   G   EP P   P     PG  G    R  PG    R   GT S    GL   
Sbjct: 1782 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER---GTGSSGPRGL--- 1835

Query: 189  DTPSPVDP 196
              P P  P
Sbjct: 1836 --PGPPGP 1841



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 27/86 (31%), Positives = 30/86 (34%), Gaps = 12/86 (13%)

Query: 17   GPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAAT----TPGPGLETAG 72
            GP G P   G          G S P E     +K    +  LP  T     PGP      
Sbjct: 1622 GPQGPPGPQGP--------NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP 1673

Query: 73   PADAPAGAVVGGGSPRGRPGPVPAPG 98
            P D       G   PRG PGP  +PG
Sbjct: 1674 PGDRGFTGKDGAMGPRGPPGPPGSPG 1699


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 51/199 (25%), Positives = 67/199 (33%), Gaps = 21/199 (10%)

Query: 41   PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAV--------VGGGSPRGRPG 92
            P  P SC   +       P     GPG +        +GA+        +G   P+G PG
Sbjct: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792

Query: 93   PVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEP--------SP 144
            P    GL  P    R    GD     L       GLP  P P G P             P
Sbjct: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852

Query: 145  ARTPAPSPGPGSCGSASPRSSPGH-----APARAALGTASGHRAGLTSRDTPSPVDPDTV 199
               P P   PGS G   P   PG       P  + L    G R  + S++    V     
Sbjct: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 2912

Query: 200  EVLMTFEPDPADLALSSIP 218
            E L++ + +  +  L+ IP
Sbjct: 2913 EQLISGQMNRFNQMLNQIP 2931



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/110 (33%), Positives = 41/110 (37%), Gaps = 12/110 (10%)

Query: 64   PGPGLETAGPADAPAGAVVGGG-SPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAF 122
            PGP     GP   P  A   G   P GRPG    PG+  P   ER LP    E     + 
Sbjct: 2941 PGP----PGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP-GERGLPGEKGERGTGSSG 2995

Query: 123  LLEHGLPPSPPPPG----GPSPEPSPARTPAPSPGPGSCGSASPRSSPGH 168
                GLP  P P G    GP         P P   PG+ G   P   PG+
Sbjct: 2996 --PRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 24/68 (35%), Positives = 24/68 (35%), Gaps = 8/68 (11%)

Query: 129  PPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASGHRAGLTSR 188
            PP PP   G   EP P   P     PG  G    R  PG    R   GT S    GL   
Sbjct: 2946 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER---GTGSSGPRGL--- 2999

Query: 189  DTPSPVDP 196
              P P  P
Sbjct: 3000 --PGPPGP 3005



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 27/86 (31%), Positives = 30/86 (34%), Gaps = 12/86 (13%)

Query: 17   GPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAAT----TPGPGLETAG 72
            GP G P   G          G S P E     +K    +  LP  T     PGP      
Sbjct: 2786 GPQGPPGPQGP--------NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP 2837

Query: 73   PADAPAGAVVGGGSPRGRPGPVPAPG 98
            P D       G   PRG PGP  +PG
Sbjct: 2838 PGDRGFTGKDGAMGPRGPPGPPGSPG 2863


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 54/181 (29%), Positives = 65/181 (35%), Gaps = 28/181 (15%)

Query: 18  PAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPGLETAGPADAP 77
           P+G P  G +  G+    +G + PKE                   TPG   ET GP+ A 
Sbjct: 487 PSGHPKAGHSENGVEEDTEGRTGPKEG------------------TPGSPSETPGPSPAG 528

Query: 78  AGAVVGGGSPRGRPGPVPA-PGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPG 136
                   SP   PGP PA P    P       P         D         P P P G
Sbjct: 529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 588

Query: 137 GPSPEP--SPARTPAPSP-GP-GSCGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPS 192
               EP  SP+ TP P P GP G   + SP  +PG  PA  A     G     +  +TP 
Sbjct: 589 PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPA-----GDEPAESPSETPG 643

Query: 193 P 193
           P
Sbjct: 644 P 644


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 55/210 (26%), Positives = 67/210 (31%), Gaps = 27/210 (12%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P +   P P     PA T P   A           + PKEPA    KE       PA TT
Sbjct: 516 PTTPEEPTPTTPEEPAPTTPKAAA----------PNTPKEPAPTTPKE-------PAPTT 558

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPV----PAPGLLAPLLWERTLPFGDVEYVDL 119
           P     T     AP        +    P P     PAP  LAP   +           D 
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS----TTCDK 614

Query: 120 DAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTAS 179
            A     G  P+ P    P+    PA T      P +    +P +    AP   A  T  
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 674

Query: 180 GHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           G  +  T+ D P+P  P         EP P
Sbjct: 675 GPTS--TTSDKPAPTTPKETAPTTPKEPAP 702



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 51/217 (23%), Positives = 63/217 (29%), Gaps = 22/217 (10%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAAL-PAAT 62
           P + + PAP     PA T P   A           + PKEPA    K+        PA T
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPAPTTTKKPAPTTPKEPAPT 477

Query: 63  TPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAF 122
           TP     T      P        +   +P P   P  LAP   E   P    E       
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPK 536

Query: 123 LLEHGLP----------PSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPAR 172
                 P          P+P  P  P+P       P    G        P  +    PA 
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596

Query: 173 AALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
             L   +      T+ D P+P  P         EP P
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 633



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 61/262 (23%), Positives = 79/262 (30%), Gaps = 24/262 (9%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P   A           + PKEP     KE       PA TT
Sbjct: 295 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPTPTTPKEPAPTTKEPAPTT 344

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPA--PGLLAPLLWERTLPFGDVEYVDLDA 121
           P     TA    AP        +    P P     P    P     T            A
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 404

Query: 122 FLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPA--RAALGTAS 179
                  P +P  P  P+    PA T    P P +    +P +    AP   +    T +
Sbjct: 405 PTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 180 GHRAGLTSRD----TPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEEL 235
              A  T ++    TP    P T + L    P+         P   T +       EE  
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523

Query: 236 -----KPQPIMKKARKIQVPEE 252
                +P P   KA     P+E
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKE 545



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 56/225 (24%), Positives = 75/225 (33%), Gaps = 49/225 (21%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P G A   L          KEPA    K+   K   P  TT
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTL----------KEPAPTTPKKPAPKELAPT-TT 673

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFL 123
            GP   T+  +D PA       +P     P P            T P             
Sbjct: 674 KGP---TSTTSDKPAPTTPKETAPTTPKEPAP------------TTP------------- 705

Query: 124 LEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSP--GHAPARAALGTASGH 181
                 P+P  P  P P  S   TP  +  P +   +   S+P     P   AL   S  
Sbjct: 706 ----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPK 760

Query: 182 RAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPR 226
             G+ +  TP+   P   E+  T +    +  L + P   T  P+
Sbjct: 761 EPGVPTTKTPAATKP---EMTTTAKDKTTERDLRTTPETTTAAPK 802



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 40/169 (23%), Positives = 52/169 (30%), Gaps = 15/169 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPAS   KE        A TTP     T   + AP        +    P P   P   
Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPT-TPKEP 278

Query: 101 APLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSA 160
           AP   +   P                  P +P  P   +P+  PA T    P P +    
Sbjct: 279 APTTTKEPAP------------TTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEP 325

Query: 161 SPRSSPGHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           +P +    AP        +      T+   P+P  P         EP P
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 38/157 (24%), Positives = 55/157 (35%), Gaps = 14/157 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPA    KE       PA TTP     T     AP        +P+  P P   P   
Sbjct: 259 PKEPAPTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPT-TPKKP 309

Query: 101 APLLWERTLPFGDVEYVDLD----AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGS 156
           AP   +   P    E         A   +   P +P  P   +P+  PA T    P P +
Sbjct: 310 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK-KPAPTTPKEPAPTT 368

Query: 157 CGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSP 193
               +P ++   +P        +  ++  T+   P+P
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 55/210 (26%), Positives = 67/210 (31%), Gaps = 27/210 (12%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P +   P P     PA T P   A           + PKEPA    KE       PA TT
Sbjct: 557 PTTPEEPTPTTPEEPAPTTPKAAA----------PNTPKEPAPTTPKE-------PAPTT 599

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPV----PAPGLLAPLLWERTLPFGDVEYVDL 119
           P     T     AP        +    P P     PAP  LAP   +           D 
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS----TTCDK 655

Query: 120 DAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTAS 179
            A     G  P+ P    P+    PA T      P +    +P +    AP   A  T  
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 715

Query: 180 GHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           G  +  T+ D P+P  P         EP P
Sbjct: 716 GPTS--TTSDKPAPTTPKETAPTTPKEPAP 743



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 51/217 (23%), Positives = 63/217 (29%), Gaps = 22/217 (10%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAAL-PAAT 62
           P + + PAP     PA T P   A           + PKEPA    K+        PA T
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPAPTTTKKPAPTTPKEPAPT 518

Query: 63  TPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAF 122
           TP     T      P        +   +P P   P  LAP   E   P    E       
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPK 577

Query: 123 LLEHGLP----------PSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPAR 172
                 P          P+P  P  P+P       P    G        P  +    PA 
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637

Query: 173 AALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
             L   +      T+ D P+P  P         EP P
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 674



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 61/262 (23%), Positives = 79/262 (30%), Gaps = 24/262 (9%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P   A           + PKEP     KE       PA TT
Sbjct: 336 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPTPTTPKEPAPTTKEPAPTT 385

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPA--PGLLAPLLWERTLPFGDVEYVDLDA 121
           P     TA    AP        +    P P     P    P     T            A
Sbjct: 386 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 445

Query: 122 FLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPA--RAALGTAS 179
                  P +P  P  P+    PA T    P P +    +P +    AP   +    T +
Sbjct: 446 PTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 180 GHRAGLTSRD----TPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEEL 235
              A  T ++    TP    P T + L    P+         P   T +       EE  
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564

Query: 236 -----KPQPIMKKARKIQVPEE 252
                +P P   KA     P+E
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKE 586



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 56/225 (24%), Positives = 75/225 (33%), Gaps = 49/225 (21%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P G A   L          KEPA    K+   K   P  TT
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTL----------KEPAPTTPKKPAPKELAPT-TT 714

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFL 123
            GP   T+  +D PA       +P     P P            T P             
Sbjct: 715 KGP---TSTTSDKPAPTTPKETAPTTPKEPAP------------TTP------------- 746

Query: 124 LEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSP--GHAPARAALGTASGH 181
                 P+P  P  P P  S   TP  +  P +   +   S+P     P   AL   S  
Sbjct: 747 ----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPK 801

Query: 182 RAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPR 226
             G+ +  TP+   P   E+  T +    +  L + P   T  P+
Sbjct: 802 EPGVPTTKTPAATKP---EMTTTAKDKTTERDLRTTPETTTAAPK 843



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 40/169 (23%), Positives = 52/169 (30%), Gaps = 15/169 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPAS   KE        A TTP     T   + AP        +    P P   P   
Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPT-TPKEP 319

Query: 101 APLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSA 160
           AP   +   P                  P +P  P   +P+  PA T    P P +    
Sbjct: 320 APTTTKEPAP------------TTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEP 366

Query: 161 SPRSSPGHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           +P +    AP        +      T+   P+P  P         EP P
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 38/157 (24%), Positives = 55/157 (35%), Gaps = 14/157 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPA    KE       PA TTP     T     AP        +P+  P P   P   
Sbjct: 300 PKEPAPTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPT-TPKKP 350

Query: 101 APLLWERTLPFGDVEYVDLD----AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGS 156
           AP   +   P    E         A   +   P +P  P   +P+  PA T    P P +
Sbjct: 351 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK-KPAPTTPKEPAPTT 409

Query: 157 CGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSP 193
               +P ++   +P        +  ++  T+   P+P
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 55/210 (26%), Positives = 67/210 (31%), Gaps = 27/210 (12%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P +   P P     PA T P   A           + PKEPA    KE       PA TT
Sbjct: 609 PTTPEEPTPTTPEEPAPTTPKAAA----------PNTPKEPAPTTPKE-------PAPTT 651

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPV----PAPGLLAPLLWERTLPFGDVEYVDL 119
           P     T     AP        +    P P     PAP  LAP   +           D 
Sbjct: 652 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS----TTCDK 707

Query: 120 DAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTAS 179
            A     G  P+ P    P+    PA T      P +    +P +    AP   A  T  
Sbjct: 708 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 767

Query: 180 GHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           G  +  T+ D P+P  P         EP P
Sbjct: 768 GPTS--TTSDKPAPTTPKETAPTTPKEPAP 795



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 51/217 (23%), Positives = 63/217 (29%), Gaps = 22/217 (10%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAAL-PAAT 62
           P + + PAP     PA T P   A           + PKEPA    K+        PA T
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPAPTTTKKPAPTTPKEPAPT 570

Query: 63  TPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAF 122
           TP     T      P        +   +P P   P  LAP   E   P    E       
Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPK 629

Query: 123 LLEHGLP----------PSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPAR 172
                 P          P+P  P  P+P       P    G        P  +    PA 
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689

Query: 173 AALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
             L   +      T+ D P+P  P         EP P
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 726



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 61/262 (23%), Positives = 79/262 (30%), Gaps = 24/262 (9%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P   A           + PKEP     KE       PA TT
Sbjct: 388 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPTPTTPKEPAPTTKEPAPTT 437

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPA--PGLLAPLLWERTLPFGDVEYVDLDA 121
           P     TA    AP        +    P P     P    P     T            A
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 497

Query: 122 FLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPA--RAALGTAS 179
                  P +P  P  P+    PA T    P P +    +P +    AP   +    T +
Sbjct: 498 PTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 180 GHRAGLTSRD----TPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEEL 235
              A  T ++    TP    P T + L    P+         P   T +       EE  
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616

Query: 236 -----KPQPIMKKARKIQVPEE 252
                +P P   KA     P+E
Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKE 638



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 56/225 (24%), Positives = 75/225 (33%), Gaps = 49/225 (21%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P G A   L          KEPA    K+   K   P  TT
Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTL----------KEPAPTTPKKPAPKELAPT-TT 766

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFL 123
            GP   T+  +D PA       +P     P P            T P             
Sbjct: 767 KGP---TSTTSDKPAPTTPKETAPTTPKEPAP------------TTP------------- 798

Query: 124 LEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSP--GHAPARAALGTASGH 181
                 P+P  P  P P  S   TP  +  P +   +   S+P     P   AL   S  
Sbjct: 799 ----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPK 853

Query: 182 RAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPR 226
             G+ +  TP+   P   E+  T +    +  L + P   T  P+
Sbjct: 854 EPGVPTTKTPAATKP---EMTTTAKDKTTERDLRTTPETTTAAPK 895



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 40/169 (23%), Positives = 52/169 (30%), Gaps = 15/169 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPAS   KE        A TTP     T   + AP        +    P P   P   
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPT-TPKEP 371

Query: 101 APLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSA 160
           AP   +   P                  P +P  P   +P+  PA T    P P +    
Sbjct: 372 APTTTKEPAP------------TTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEP 418

Query: 161 SPRSSPGHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           +P +    AP        +      T+   P+P  P         EP P
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 467



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 38/157 (24%), Positives = 55/157 (35%), Gaps = 14/157 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPA    KE       PA TTP     T     AP        +P+  P P   P   
Sbjct: 352 PKEPAPTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPT-TPKKP 402

Query: 101 APLLWERTLPFGDVEYVDLD----AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGS 156
           AP   +   P    E         A   +   P +P  P   +P+  PA T    P P +
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK-KPAPTTPKEPAPTT 461

Query: 157 CGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSP 193
               +P ++   +P        +  ++  T+   P+P
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 55/210 (26%), Positives = 67/210 (31%), Gaps = 27/210 (12%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P +   P P     PA T P   A           + PKEPA    KE       PA TT
Sbjct: 650 PTTPEEPTPTTPEEPAPTTPKAAA----------PNTPKEPAPTTPKE-------PAPTT 692

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPV----PAPGLLAPLLWERTLPFGDVEYVDL 119
           P     T     AP        +    P P     PAP  LAP   +           D 
Sbjct: 693 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS----TTCDK 748

Query: 120 DAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTAS 179
            A     G  P+ P    P+    PA T      P +    +P +    AP   A  T  
Sbjct: 749 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 808

Query: 180 GHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           G  +  T+ D P+P  P         EP P
Sbjct: 809 GPTS--TTSDKPAPTTPKETAPTTPKEPAP 836



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 51/217 (23%), Positives = 63/217 (29%), Gaps = 22/217 (10%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAAL-PAAT 62
           P + + PAP     PA T P   A           + PKEPA    K+        PA T
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPAPTTTKKPAPTTPKEPAPT 611

Query: 63  TPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAF 122
           TP     T      P        +   +P P   P  LAP   E   P    E       
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPK 670

Query: 123 LLEHGLP----------PSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPAR 172
                 P          P+P  P  P+P       P    G        P  +    PA 
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730

Query: 173 AALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
             L   +      T+ D P+P  P         EP P
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 767



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 61/262 (23%), Positives = 79/262 (30%), Gaps = 24/262 (9%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P   A           + PKEP     KE       PA TT
Sbjct: 429 PTTPKEPAPTTPKKPAPTTPKEPA----------PTTPKEPTPTTPKEPAPTTKEPAPTT 478

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPA--PGLLAPLLWERTLPFGDVEYVDLDA 121
           P     TA    AP        +    P P     P    P     T            A
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 538

Query: 122 FLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPA--RAALGTAS 179
                  P +P  P  P+    PA T    P P +    +P +    AP   +    T +
Sbjct: 539 PTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 180 GHRAGLTSRD----TPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEEL 235
              A  T ++    TP    P T + L    P+         P   T +       EE  
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657

Query: 236 -----KPQPIMKKARKIQVPEE 252
                +P P   KA     P+E
Sbjct: 658 PTTPEEPAPTTPKAAAPNTPKE 679



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 56/225 (24%), Positives = 75/225 (33%), Gaps = 49/225 (21%)

Query: 4   PVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATT 63
           P + + PAP     PA T P G A   L          KEPA    K+   K   P  TT
Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTL----------KEPAPTTPKKPAPKELAPT-TT 807

Query: 64  PGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFL 123
            GP   T+  +D PA       +P     P P            T P             
Sbjct: 808 KGP---TSTTSDKPAPTTPKETAPTTPKEPAP------------TTP------------- 839

Query: 124 LEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSP--GHAPARAALGTASGH 181
                 P+P  P  P P  S   TP  +  P +   +   S+P     P   AL   S  
Sbjct: 840 ----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPK 894

Query: 182 RAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPR 226
             G+ +  TP+   P   E+  T +    +  L + P   T  P+
Sbjct: 895 EPGVPTTKTPAATKP---EMTTTAKDKTTERDLRTTPETTTAAPK 936



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 40/169 (23%), Positives = 52/169 (30%), Gaps = 15/169 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPAS   KE        A TTP     T   + AP        +    P P   P   
Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPT-TPKEP 412

Query: 101 APLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSA 160
           AP   +   P                  P +P  P   +P+  PA T    P P +    
Sbjct: 413 APTTTKEPAP------------TTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEP 459

Query: 161 SPRSSPGHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP 209
           +P +    AP        +      T+   P+P  P         EP P
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 508



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 38/157 (24%), Positives = 55/157 (35%), Gaps = 14/157 (8%)

Query: 41  PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLL 100
           PKEPA    KE       PA TTP     T     AP        +P+  P P   P   
Sbjct: 393 PKEPAPTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPT-TPKKP 443

Query: 101 APLLWERTLPFGDVEYVDLD----AFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGS 156
           AP   +   P    E         A   +   P +P  P   +P+  PA T    P P +
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK-KPAPTTPKEPAPTT 502

Query: 157 CGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSP 193
               +P ++   +P        +  ++  T+   P+P
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539


>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform c [Homo sapiens]
          Length = 1152

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 50/161 (31%), Positives = 63/161 (39%), Gaps = 25/161 (15%)

Query: 50   KEKERKAALPAATTPGPGLETAGP------ADAPAGAV---VGGGSPRGRPGPVPAPGLL 100
            ++++   ALP  + P P    AGP      A APA  V    G G+P G  GP    G  
Sbjct: 988  QQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA 1047

Query: 101  APLLW-ERTLPFGDVEYVDLDAFLLEHGLPPSPPPPG--GPSPEPSPARTPAPSPG--PG 155
                  ++  P G  +            +PP  PPPG  GPSP P+    P+  PG  PG
Sbjct: 1048 GSTAGPQQQQPAGAPQ---------PGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPG 1098

Query: 156  SCGSASPRSSPGHAPARAALGTASGHRAGLTSRDTPSPVDP 196
            S        SP  A   A  G      + L    TP P DP
Sbjct: 1099 SGHPGVAAQSP--AIVAAVQGNLLPSASPLPDPGTPLPPDP 1137



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 41/157 (26%), Positives = 58/157 (36%), Gaps = 9/157 (5%)

Query: 12   PLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPGLETA 71
            P+   G AG P   G  +   S++   +    P   L   ++   A    +T GP  +  
Sbjct: 1002 PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQA---GSTAGP--QQQ 1056

Query: 72   GPADAPA-GAVVGGGSPRGRPGPVPAPGLLAP-LLWERTLPFGDVEYVDLDAFLLEHGLP 129
             PA AP  GAV  G  P G  GP P P    P  +    +P      V   +  +   + 
Sbjct: 1057 QPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQ 1116

Query: 130  PSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSP 166
             +  P    SP P P     P P   S G+ +P   P
Sbjct: 1117 GNLLPSA--SPLPDPGTPLPPDPTAPSPGTVTPVPPP 1151


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 60/226 (26%), Positives = 82/226 (36%), Gaps = 45/226 (19%)

Query: 2   ARPVSDRTPAPLLLGGPAGTPPGGGALLGLRSLLQGTSKPKEP--------ASCLLKEKE 53
           A P    TPAP     PA  P    A    R+  +   +P  P         +  +++  
Sbjct: 503 AVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMA 562

Query: 54  RKAALPAATTPG-PGLETAGPADAPAGAVV--GGGSPRGRPGPVPAPGLLAPLLWERTLP 110
           R+   PA   P  P  + +G   +P    +  G GSP G P  +P   L+   L   T+P
Sbjct: 563 RRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSP-GTPQALPRR-LVGSSLRAPTVP 620

Query: 111 FGDVEYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAP 170
                             PP PP P  P P    +R    SP P S G ASP       P
Sbjct: 621 ------------------PPLPPTP--PQPARRQSRRSPASPSPASPGPASPSPVSLSNP 660

Query: 171 ARAALGTAS---GHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLA 213
           A+  LG A+   G    ++   TP  + P         +P P  LA
Sbjct: 661 AQVDLGAATAEGGAPEAISGVPTPPAIPP---------QPRPRSLA 697



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 2/52 (3%)

Query: 123 LLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAPARAA 174
           L    LP +  P    +P P+PA  PAP+P   S  +A+   +    P R A
Sbjct: 494 LASEELPSTAVPTPATTPAPAPAPAPAPAPALAS--AATKERTESEVPPRPA 543


>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
           sapiens]
          Length = 837

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 2/76 (2%)

Query: 123 LLEHGLPPSPPPPGGPSP--EPSPARTPAPSPGPGSCGSASPRSSPGHAPARAALGTASG 180
           + E    P+P P   P P   P+PA TP P+P P S    +P  +P  APA A  G+   
Sbjct: 1   MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 60

Query: 181 HRAGLTSRDTPSPVDP 196
              G+ S    S  DP
Sbjct: 61  GGPGVGSGGAGSGGDP 76



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 32/111 (28%), Positives = 37/111 (33%), Gaps = 37/111 (33%)

Query: 71  AGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFGDVEYVDLDAFLLEHGLPP 130
           A P+ AP  A      P   P P P P                                P
Sbjct: 2   AEPSQAPTPAPAAQPRPLQSPAPAPTP-------------------------------TP 30

Query: 131 SPPPPGGPSPEPSPARTPAPSPGP-GSCGSASPRSSPGHA-----PARAAL 175
           +P P   P P P+PA  PAP+  P GS G+  P    G A     PAR  L
Sbjct: 31  APSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGL 81


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,069,322
Number of Sequences: 37866
Number of extensions: 1490160
Number of successful extensions: 34316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 911
Number of HSP's successfully gapped in prelim test: 1538
Number of HSP's that attempted gapping in prelim test: 12131
Number of HSP's gapped (non-prelim): 12191
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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