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Search of human proteins with 30179900
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
(391 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 803 0.0
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 391 e-109
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 347 8e-96
gi|5902108 SRY-box 21 [Homo sapiens] 206 4e-53
gi|4759162 SRY-box 14 [Homo sapiens] 176 3e-44
gi|5902106 SRY-box 15 [Homo sapiens] 145 8e-35
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 144 1e-34
gi|4507161 SRY-box 11 [Homo sapiens] 139 3e-33
gi|11967991 SRY-box 17 [Homo sapiens] 131 1e-30
gi|13899269 SRY-box 7 [Homo sapiens] 129 3e-30
gi|4507225 sex determining region Y [Homo sapiens] 129 5e-30
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 128 8e-30
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 124 1e-28
gi|4557853 transcription factor SOX9 [Homo sapiens] 124 2e-28
gi|8924248 SRY-box 18 [Homo sapiens] 121 1e-27
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 120 3e-27
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 106 4e-23
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 106 4e-23
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 106 4e-23
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 102 8e-22
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 102 8e-22
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 102 8e-22
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 102 8e-22
gi|41406089 SRY-box 13 [Homo sapiens] 100 2e-21
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 87 3e-17
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 87 3e-17
gi|112421108 capicua homolog [Homo sapiens] 76 5e-14
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 64 2e-10
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 64 2e-10
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa... 59 6e-09
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 803 bits (2073), Expect = 0.0
Identities = 391/391 (100%), Positives = 391/391 (100%)
Query: 1 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMV 60
MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMV
Sbjct: 1 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMV 60
Query: 61 WSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY 120
WSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY
Sbjct: 61 WSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY 120
Query: 121 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGG 180
RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGG
Sbjct: 121 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGG 180
Query: 181 YAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHP 240
YAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHP
Sbjct: 181 YAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHP 240
Query: 241 HNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAA 300
HNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAA
Sbjct: 241 HNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAA 300
Query: 301 AAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAA 360
AAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAA
Sbjct: 301 AAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAA 360
Query: 361 AAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI 391
AAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI
Sbjct: 361 AAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI 391
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 391 bits (1005), Expect = e-109
Identities = 228/389 (58%), Positives = 260/389 (66%), Gaps = 53/389 (13%)
Query: 12 SPGGA-QAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMA 70
+PGGA ++ N +G A +GGG GG GGGGG +QDRVKRPMNAFMVWSRGQRRKMA
Sbjct: 102 APGGAGKSSANAAGGANSGGGSSGGASGGGGG---TDQDRVKRPMNAFMVWSRGQRRKMA 158
Query: 71 QENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLL 130
ENPKMHNSEISKRLGA+WK++++AEKRPFIDEAKRLRA+HMKE+PDYKYRPRRKTKTLL
Sbjct: 159 LENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLL 218
Query: 131 KKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANG 190
KKDKYSL GLL GA AA A VGQRL++ Y HVNGWANG
Sbjct: 219 KKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDT--------YTHVNGWANG 270
Query: 191 AYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYD 250
AY +++QE QL Y Q P + P PA P PMHRYD
Sbjct: 271 AY-----------SLVQE-QLGYAQPPSM--SSPPPPPALP-------------PMHRYD 303
Query: 251 MGALQYSPI--SNSQGYM-----SASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAA 303
M LQYSP+ +Q YM +A+ SGYGG+ A AAAAAA G Q A AAAAAA
Sbjct: 304 MAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYG---QQPATAAAAAA 360
Query: 304 AAASSGALGALGSLVKSEPSGSPPAPA-HSRAPCPGDLREMISMYLPAGEGGDPAAAAAA 362
AAA+ +LG +GS+VKSEPS PPA A HS+ C GDLR+MISMYLP GGD A AA+
Sbjct: 361 AAAAM-SLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLP--PGGDAADAASP 417
Query: 363 AAQSRLHSLPQHYQGAGAGVNGTVPLTHI 391
RLH + QHYQGAG VNGTVPLTHI
Sbjct: 418 LPGGRLHGVHQHYQGAGTAVNGTVPLTHI 446
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 347 bits (891), Expect = 8e-96
Identities = 211/399 (52%), Positives = 250/399 (62%), Gaps = 90/399 (22%)
Query: 1 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMV 60
MY+MM ET+L PG Q +GGGGG GG K + DRVKRPMNAFMV
Sbjct: 1 MYNMM-ETELKPPGPQQT---------SGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMV 50
Query: 61 WSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY 120
WSRGQRRKMAQENPKMHNSEISKRLGAEWK++SE EKRPFIDEAKRLRALHMKEHPDYKY
Sbjct: 51 WSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKY 110
Query: 121 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG-AAAVGQRLESPGGAAGG 179
RPRRKTKTL+KKDKY+L GGLLA GG ++A GVGVG G A V QR++S
Sbjct: 111 RPRRKTKTLMKKDKYTLPGGLLAP----GGNSMASGVGVGAGLGAGVNQRMDS------- 159
Query: 180 GYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAH 239
YAH+NGW+NG+Y +MMQ+ QL Y QHPG +AH A
Sbjct: 160 -YAHMNGWSNGSY-----------SMMQD-QLGYPQHPGL-----NAHGA---------- 191
Query: 240 PHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAA 299
QPMHRYD+ ALQY+ +++SQ YM+ SP+ Y + + G
Sbjct: 192 -AQMQPMHRYDVSALQYNSMTSSQTYMNGSPT------YSMSYSQQGTPG---------- 234
Query: 300 AAAAAAASSGALGALGSLVKSEPSGSPP---APAHSRAPC-PGDLREMISMYLPAGEGGD 355
ALG++GS+VKSE S SPP + +HSRAPC GDLR+MISMYLP E +
Sbjct: 235 ---------MALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPE 285
Query: 356 PAAAAAAAAQSRLHSLPQHYQGA---GAGVNGTVPLTHI 391
P AA SRLH + QHYQ G +NGT+PL+H+
Sbjct: 286 P------AAPSRLH-MSQHYQSGPVPGTAINGTLPLSHM 317
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 206 bits (523), Expect = 4e-53
Identities = 149/323 (46%), Positives = 172/323 (53%), Gaps = 60/323 (18%)
Query: 49 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLR 108
D VKRPMNAFMVWSR QRRKMAQENPKMHNSEISKRLGAEWK+++E+EKRPFIDEAKRLR
Sbjct: 6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65
Query: 109 ALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQ 168
A+HMKEHPDYKYRPRRK KTLLKKDK++ + G GG A + G G A
Sbjct: 66 AMHMKEHPDYKYRPRRKPKTLLKKDKFAFP---VPYGLGGVADAEHPALKAGAGLHA--- 119
Query: 169 RLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHP 228
AGGG + AN P AAAAAAAA A++ + Q A A A
Sbjct: 120 -------GAGGGLVPESLLAN---PEKAAAAAAAAA----ARVFFPQSAAAAAAAAAAAA 165
Query: 229 AHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAA 288
A P D+G+ M+ S GLPY ++ A
Sbjct: 166 AG-------------SPYSLLDLGSK-----------MAEISSSSSGLPYASSLGYPTAG 201
Query: 289 GGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPA---PAHSRA-PCPGDLREMI 344
GA +A AAAAAAAAA G S PS P P + A P PG L+ +
Sbjct: 202 AGAFHGAAAAAAAAAAAA--------GGHTHSHPSPGNPGYMIPCNCSAWPSPG-LQPPL 252
Query: 345 SMYLPAGEGG---DPAAAAAAAA 364
+ L G G DP AA AAA
Sbjct: 253 AYILLPGMGKPQLDPYPAAYAAA 275
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/104 (41%), Positives = 50/104 (48%), Gaps = 25/104 (24%)
Query: 280 AAAAAAAAAGGAHQNSAVAAAAAAAAASSGA------LGALGSLVKSEPSGSPPAPAHSR 333
AAAAAAAAA SA AAAAAAAAA++G+ LG+ + + S SG P A +
Sbjct: 138 AAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLG- 196
Query: 334 APCPGDLREMISMYLPAGEG-----GDPAAAAAAAAQSRLHSLP 372
Y AG G AAAAAAAA HS P
Sbjct: 197 -------------YPTAGAGAFHGAAAAAAAAAAAAGGHTHSHP 227
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 176 bits (446), Expect = 3e-44
Identities = 101/193 (52%), Positives = 119/193 (61%), Gaps = 10/193 (5%)
Query: 49 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLR 108
D +KRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWK++SEAEKRP+IDEAKRLR
Sbjct: 6 DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLR 65
Query: 109 ALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQ 168
A HMKEHPDYKYRPRRK K LLKKD+Y L A + +G G+ +A
Sbjct: 66 AQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKA 125
Query: 169 RLESPGGAAGGGYAHVNGWANGAYP--GSVAAAAAAAAMMQEAQLAYGQHPGAGGA---- 222
R P +A +++ A G V A A+ + L Y GA G+
Sbjct: 126 RAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGY--QNGAFGSLSCP 183
Query: 223 --HPHAHPAHPHP 233
H H HP+ +P
Sbjct: 184 SQHTHTHPSPTNP 196
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 145 bits (365), Expect = 8e-35
Identities = 94/236 (39%), Positives = 118/236 (50%), Gaps = 37/236 (15%)
Query: 10 LHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKM 69
L P A ++ SGP G G G ++VKRPMNAFMVWS QRR+M
Sbjct: 14 LEPPAATAAASSSSGPQEREGAGSPAAPG------TLPLEKVKRPMNAFMVWSSAQRRQM 67
Query: 70 AQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTL 129
AQ+NPKMHNSEISKRLGA+WK++ E EKRPF++EAKRLRA H++++PDYKYRPRRK K
Sbjct: 68 AQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAK-- 125
Query: 130 LKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAA-----GGGYAHV 184
++GAG G G G A G L PG A G GY
Sbjct: 126 -------------SSGAGPSRC------GQGRGNLASGGPLWGPGYATTQPSRGFGY-RP 165
Query: 185 NGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHP----HAHPAHPHPHHP 236
++ PGS ++ L G P + P P P++P
Sbjct: 166 PSYSTAYLPGSYGSSHCKLEAPSPCSLPQSDPRLQGELLPTYTHYLPPGSPTPYNP 221
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 144 bits (364), Expect = 1e-34
Identities = 114/363 (31%), Positives = 151/363 (41%), Gaps = 40/363 (11%)
Query: 12 SPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQ 71
S GA ++ G GG K +KRPMNAFMVWS+ +RRK+ +
Sbjct: 20 SDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIME 79
Query: 72 ENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLK 131
++P MHN+EISKRLG WK++ +++K PFI EA+RLR HM ++PDYKYRPR+K K+
Sbjct: 80 QSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNA 139
Query: 132 KDKYSLA------------GGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESP------ 173
S A GG G GGGG + G G G A+ G P
Sbjct: 140 NSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSC 199
Query: 174 ----GGAAGGGYAHVNG---WANGAYPGSVAAAAAAAAMMQEA---------------QL 211
G AGGG + + A G G AAAAAA+ ++A L
Sbjct: 200 GSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSL 259
Query: 212 AYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPS 271
+ P A + A A P H + Y G L S A PS
Sbjct: 260 YKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPS 319
Query: 272 GYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAH 331
GL A + A S+ A++ AA + + G S S P+ A
Sbjct: 320 DPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSSAPSHAS 379
Query: 332 SRA 334
S A
Sbjct: 380 SSA 382
Score = 30.8 bits (68), Expect = 2.2
Identities = 30/120 (25%), Positives = 43/120 (35%), Gaps = 5/120 (4%)
Query: 247 HRYDMGALQYSPISN--SQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAA 304
H D +Y P S S+S + P + GG H ++
Sbjct: 119 HMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGG---GGGSS 175
Query: 305 AASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAA 364
A G GA G S+P+ + G + + + + AG GG AAAAAAA
Sbjct: 176 NAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAA 235
Score = 29.3 bits (64), Expect = 6.4
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 21/93 (22%)
Query: 272 GYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAH 331
G+GG G ++ A GGA A + A + S G G V S+P H
Sbjct: 165 GHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGV-SKP--------H 215
Query: 332 SRAPCPGDLREMISMYLPAGEGGDPAAAAAAAA 364
++ + L G GG AAAAAAA+
Sbjct: 216 AK------------LILAGGGGGGKAAAAAAAS 236
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 139 bits (351), Expect = 3e-33
Identities = 104/322 (32%), Positives = 140/322 (43%), Gaps = 52/322 (16%)
Query: 45 KANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEA 104
K +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK++ ++EK PFI EA
Sbjct: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
Query: 105 KRLRALHMKEHPDYKYRPRRKTK--------TLLKKDKYSLAGGLLAAGAGGGGAAVAMG 156
+RLR HM ++PDYKYRPR+K K +K + GG +AG G GGA + G
Sbjct: 103 ERLRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKG 162
Query: 157 ---------VGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMM- 206
GA A + G G G +V G + G A +
Sbjct: 163 SSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFL 222
Query: 207 ----------QEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQP---MHRYDMGA 253
E QL Q P P PH P QP + RY++
Sbjct: 223 DEDDDDDDDDDELQLQIKQEPDEEDEEP--------PHQQLLQPPGQQPSQLLRRYNVAK 274
Query: 254 LQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAH----------QNSAVAAAAAA 303
+ SP +S + SP G A A + A GG+ Q+ A A
Sbjct: 275 VPASPTLSSS---AESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPAL 331
Query: 304 AAASSGALGALGSLVKSEPSGS 325
+ ASS ++ S SGS
Sbjct: 332 SPASSRSVSTSSSSSSGSSSGS 353
Score = 36.6 bits (83), Expect = 0.040
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 19 PTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKR 53
P+ P + GGGGG GGG GGAK ++ K+
Sbjct: 132 PSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKK 166
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 131 bits (329), Expect = 1e-30
Identities = 68/148 (45%), Positives = 96/148 (64%), Gaps = 18/148 (12%)
Query: 17 QAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKM 76
+AP N PAGA G G + R++RPMNAFMVW++ +R+++AQ+NP +
Sbjct: 47 EAPANSGAPAGAAGRAKG-------------ESRIRRPMNAFMVWAKDERKRLAQQNPDL 93
Query: 77 HNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT-LLKKDKY 135
HN+E+SK LG WK ++ AEKRPF++EA+RLR HM++HP+YKYRPRR+ + LK+ +
Sbjct: 94 HNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEG 153
Query: 136 SLAGGLL---AAGAGGGGAAVAM-GVGV 159
GL AA G G VAM G+G+
Sbjct: 154 GFLHGLAEPQAAALGPEGGRVAMDGLGL 181
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 129 bits (325), Expect = 3e-30
Identities = 90/271 (33%), Positives = 136/271 (50%), Gaps = 31/271 (11%)
Query: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
G K ++ R++RPMNAFMVW++ +R+++A +NP +HN+E+SK LG WK ++ ++KRP++D
Sbjct: 37 GDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVD 96
Query: 103 EAKRLRALHMKEHPDYKYRPRRK--TKTLLKKDK-----YSLAGGLLAAGAGGGGAAVAM 155
EA+RLR HM+++P+YKYRPRRK K L K+ SL+ A G+ A+
Sbjct: 97 EAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGAL 156
Query: 156 GVGVGVGAAAVGQRL--------ESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAM-M 206
G G + G L E P G GGG + YP + + + +
Sbjct: 157 GEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPS----SVDTYPYGLPTPPEMSPLDV 212
Query: 207 QEAQLAYGQHPGAGGAHPHAHPAH-PH-PHHPHAHPHNPQPMH-RYDMGALQYSPISNSQ 263
E + + P H HP PH P HP++ + P P+H + +G+L + S
Sbjct: 213 LEPEQTFFSSP---CQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSL---ALGQSP 266
Query: 264 GYMSASPSGYGGLPYGAAAAAAAAAGGAHQN 294
G SP G P A + A H N
Sbjct: 267 GVSMMSP--VPGCPPSPAYYSPATYHPLHSN 295
>gi|4507225 sex determining region Y [Homo sapiens]
Length = 204
Score = 129 bits (324), Expect = 5e-30
Identities = 61/92 (66%), Positives = 77/92 (83%), Gaps = 1/92 (1%)
Query: 41 GGGAKAN-QDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRP 99
G +K N QDRVKRPMNAF+VWSR QRRKMA ENP+M NSEISK+LG +WK+++EAEK P
Sbjct: 49 GENSKGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWP 108
Query: 100 FIDEAKRLRALHMKEHPDYKYRPRRKTKTLLK 131
F EA++L+A+H +++P+YKYRPRRK K L K
Sbjct: 109 FFQEAQKLQAMHREKYPNYKYRPRRKAKMLPK 140
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 128 bits (322), Expect = 8e-30
Identities = 62/124 (50%), Positives = 81/124 (65%), Gaps = 2/124 (1%)
Query: 39 GGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKR 98
GGGGGA + VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+++SE+EKR
Sbjct: 90 GGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKR 149
Query: 99 PFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVG 158
PF++EA+RLR H K+HPDYKY+PRR+ K G GGGA G
Sbjct: 150 PFVEEAERLRVQHKKDHPDYKYQPRRRKSA--KAGHSDSDSGAELGPHPGGGAVYKAEAG 207
Query: 159 VGVG 162
+G G
Sbjct: 208 LGDG 211
Score = 29.6 bits (65), Expect = 4.9
Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)
Query: 173 PGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPH 232
PG A GG Y H GA P +A +A+ A P
Sbjct: 299 PGQAYGGAYFHA-----GASPVWAHKSAPSAS---------------------ASPTETG 332
Query: 233 PHHPHAHPHNPQPMHRYDM--GALQYSPISNSQGYMSASPSG 272
P PH P P H D G+ Y S A+P+G
Sbjct: 333 PPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAG 374
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 124 bits (312), Expect = 1e-28
Identities = 98/329 (29%), Positives = 138/329 (41%), Gaps = 96/329 (29%)
Query: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
GA ++ VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W++++E++KRPFI+
Sbjct: 96 GASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIE 155
Query: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG 162
EA+RLR H K+HPDYKY+PRR+ G
Sbjct: 156 EAERLRMQHKKDHPDYKYQPRRRKN----------------------------------G 181
Query: 163 AAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGA 222
AA G+ E PGG A G AA A + A L + +HPG G
Sbjct: 182 KAAQGE-AECPGGEAEQG-----------------GTAAIQAHYKSAHLDH-RHPGEGSP 222
Query: 223 HPHAHPAHP--HPHHPHAHPHNPQ-------------------------PMHRYDMGALQ 255
+P HP H P P P+ D+G +
Sbjct: 223 MSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEIS 282
Query: 256 YSPISNSQGYMSAS------PSG-------YGGLPYGAAAAAAAAAGGAHQNSAVAAAAA 302
+ +SN + + A P+G Y YG +A A A+G + S A
Sbjct: 283 HEVMSNMETFDVAELDQYLPPNGHPGHVSSYSAAGYGLGSALAVASGHSAWISKPPGVAL 342
Query: 303 AAAASSGALGALGSLVKSEPSGSPPAPAH 331
+ G + VK+E +G P P H
Sbjct: 343 PTVSPPGV--DAKAQVKTETAG-PQGPPH 368
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 124 bits (310), Expect = 2e-28
Identities = 96/336 (28%), Positives = 139/336 (41%), Gaps = 57/336 (16%)
Query: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
G+ N+ VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W++++E+EKRPF++
Sbjct: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
Query: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG 162
EA+RLR H K+HPDYKY+PRR+ S+ G A +
Sbjct: 157 EAERLRVQHKKDHPDYKYQPRRRK---------SVKNGQAEA------EEATEQTHISPN 201
Query: 163 AAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGA 222
A + +SP ++G H G +G G +Q PG
Sbjct: 202 AIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQ---------PGKADL 252
Query: 223 HPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGY------MSASPSGYGGL 276
P P P D+G L ISN + + P+G+ G+
Sbjct: 253 KREGRPL------PEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGV 306
Query: 277 PYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPP-APAHSRAP 335
P A + S ++ AA AS+G + P PP AP +AP
Sbjct: 307 P-------ATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAP 359
Query: 336 CPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSL 371
P + P AA Q + H+L
Sbjct: 360 -------------PQPQAAPPQQPAAPPQQPQAHTL 382
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 121 bits (303), Expect = 1e-27
Identities = 59/134 (44%), Positives = 86/134 (64%), Gaps = 4/134 (2%)
Query: 12 SPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQ 71
+P +P S P G G G G A++ R++RPMNAFMVW++ +R+++AQ
Sbjct: 47 APASPPSPQR-SPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQ 105
Query: 72 ENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLK 131
+NP +HN+ +SK LG WK ++ AEKRPF++EA+RLR H+++HP+YKYRPRRK +
Sbjct: 106 QNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQA--- 162
Query: 132 KDKYSLAGGLLAAG 145
+ L GLL G
Sbjct: 163 RKARRLEPGLLLPG 176
Score = 30.8 bits (68), Expect = 2.2
Identities = 32/95 (33%), Positives = 39/95 (41%), Gaps = 17/95 (17%)
Query: 266 MSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGS 325
M SP GYG A A ++ A A AAA + G +L S
Sbjct: 1 MQRSPPGYG----------AQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPAS 50
Query: 326 PPAPAHS--RAPCPGDLREMISMYLPAGEGGDPAA 358
PP+P S R+P PG R +S PAG G AA
Sbjct: 51 PPSPQRSPPRSPEPG--RYGLS---PAGRGERQAA 80
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 120 bits (300), Expect = 3e-27
Identities = 69/154 (44%), Positives = 92/154 (59%), Gaps = 13/154 (8%)
Query: 30 GGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEW 89
G G G G K +KRPMNAFMVWS+ +RRK+ + P MHN+EISKRLG W
Sbjct: 19 GPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRW 78
Query: 90 KVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGG 149
+++ ++EK PF+ EA+RLR HM ++PDYKYRPR+K+K K + GG GG
Sbjct: 79 QLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGG------SGG 132
Query: 150 GAAVAMGVGV-GVGAAAVGQRLESPGGAAGGGYA 182
G+ + G + G G G+R + GG GGG A
Sbjct: 133 GSRLKPGPQLPGRG----GRR--AAGGPLGGGAA 160
Score = 29.6 bits (65), Expect = 4.9
Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 13 PGGAQAPTNLS-GPAGAGGGGGGGGGGGGGGGAKANQD 49
PGG+ + L GP G GG GG GGGA A +D
Sbjct: 127 PGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPED 164
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 106 bits (264), Expect = 4e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Query: 21 NLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSE 80
NLSG + G G +N+ +KRPMNAFMVW++ +RRK+ Q P MHNS
Sbjct: 140 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 199
Query: 81 ISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
ISK LG+ WK M+ EK+P+ +E RL H++++PDYKY+PR K L+ K
Sbjct: 200 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 253
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 106 bits (264), Expect = 4e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Query: 21 NLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSE 80
NLSG + G G +N+ +KRPMNAFMVW++ +RRK+ Q P MHNS
Sbjct: 513 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 572
Query: 81 ISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
ISK LG+ WK M+ EK+P+ +E RL H++++PDYKY+PR K L+ K
Sbjct: 573 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 626
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 106 bits (264), Expect = 4e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Query: 21 NLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSE 80
NLSG + G G +N+ +KRPMNAFMVW++ +RRK+ Q P MHNS
Sbjct: 526 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 585
Query: 81 ISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
ISK LG+ WK M+ EK+P+ +E RL H++++PDYKY+PR K L+ K
Sbjct: 586 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 639
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 102 bits (253), Expect = 8e-22
Identities = 44/92 (47%), Positives = 65/92 (70%)
Query: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
G +++ +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK MS EK+P+ +
Sbjct: 626 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 685
Query: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
E RL +H++++P+YKY+PR K ++ K
Sbjct: 686 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 717
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 102 bits (253), Expect = 8e-22
Identities = 44/92 (47%), Positives = 65/92 (70%)
Query: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
G +++ +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK MS EK+P+ +
Sbjct: 586 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 645
Query: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
E RL +H++++P+YKY+PR K ++ K
Sbjct: 646 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 677
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 102 bits (253), Expect = 8e-22
Identities = 44/92 (47%), Positives = 65/92 (70%)
Query: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
G +++ +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK MS EK+P+ +
Sbjct: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
Query: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
E RL +H++++P+YKY+PR K ++ K
Sbjct: 649 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 680
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 102 bits (253), Expect = 8e-22
Identities = 44/92 (47%), Positives = 65/92 (70%)
Query: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
G +++ +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK MS EK+P+ +
Sbjct: 593 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 652
Query: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
E RL +H++++P+YKY+PR K ++ K
Sbjct: 653 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 684
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 100 bits (250), Expect = 2e-21
Identities = 43/85 (50%), Positives = 61/85 (71%)
Query: 47 NQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKR 106
N +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK M+ EK+P+ +E R
Sbjct: 420 NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQAR 479
Query: 107 LRALHMKEHPDYKYRPRRKTKTLLK 131
L H++++PDYKY+PR K +++
Sbjct: 480 LSRQHLEKYPDYKYKPRPKRTCIVE 504
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 87.0 bits (214), Expect = 3e-17
Identities = 38/80 (47%), Positives = 56/80 (70%)
Query: 44 AKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDE 103
+K VKRPMNAFMVW+R R +A+ NP +N+EIS +LG EW +SE +K+P+ DE
Sbjct: 330 SKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDE 389
Query: 104 AKRLRALHMKEHPDYKYRPR 123
A++++ H +E P + Y+PR
Sbjct: 390 AQKIKEKHREEFPGWVYQPR 409
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 87.0 bits (214), Expect = 3e-17
Identities = 38/80 (47%), Positives = 56/80 (70%)
Query: 44 AKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDE 103
+K VKRPMNAFMVW+R R +A+ NP +N+EIS +LG EW +SE +K+P+ DE
Sbjct: 330 SKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDE 389
Query: 104 AKRLRALHMKEHPDYKYRPR 123
A++++ H +E P + Y+PR
Sbjct: 390 AQKIKEKHREEFPGWVYQPR 409
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 76.3 bits (186), Expect = 5e-14
Identities = 51/159 (32%), Positives = 76/159 (47%), Gaps = 10/159 (6%)
Query: 45 KANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEA 104
K +D ++RPMNAFM++S+ R + Q +P N +SK LG W + EK+ + D A
Sbjct: 194 KREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLA 253
Query: 105 KRLRALHMKEHPDYKY--RPRRKTKTLLKKDKYSLAGG---LLAAGAGGGGAAVAMGVGV 159
+++ H K HPD+K+ + R+K+ + K LAGG G A A GV
Sbjct: 254 FQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSS 313
Query: 160 GVGAAAVGQRLES----PGGAA-GGGYAHVNGWANGAYP 193
+ + A L S PG ++ G H G A P
Sbjct: 314 ELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARP 352
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 64.3 bits (155), Expect = 2e-10
Identities = 85/301 (28%), Positives = 110/301 (36%), Gaps = 59/301 (19%)
Query: 137 LAGGLLAAGAGGGGAAVAMGVGVGVGAA--------------AVGQRLESPGGAAGGGY- 181
L G + G GGGG A G G G GA A+ L P G GGG
Sbjct: 73 LQDGAESNGGGGGGGA---GSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129
Query: 182 -----------------AHVNGWANGAYPGSVAAAAAAAAMMQEAQ-----LAYGQHPGA 219
A+ G G P +VAAAAAA Q LA Q G
Sbjct: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
Query: 220 GGAHPHAHPA-HPHPHHPHAHPHNPQPMHR--YDMGALQY---SPISNSQGYMSASPSGY 273
GG P+A P + H H H +N +R Y A Y SP + G +A+ +G
Sbjct: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249
Query: 274 GGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSG-----ALGALGSLVKSEPSGSP-- 326
P +A+A+++++ A Q +AA G A L L+ S S
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
Query: 327 --PAPAHSRAPCPGDL----REMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQGAGA 380
P +S P G +M S A AAAA+ AQ R H P +G
Sbjct: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369
Query: 381 G 381
G
Sbjct: 370 G 370
Score = 54.7 bits (130), Expect = 1e-07
Identities = 90/356 (25%), Positives = 122/356 (34%), Gaps = 59/356 (16%)
Query: 24 GPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISK 83
G GGGGGGG G GGG GA+ + S G A P ++N+ +++
Sbjct: 76 GAESNGGGGGGGAGSGGGPGAEPDLKN-----------SNGN----AGPRPALNNN-LTE 119
Query: 84 RLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY-RPRRKTKTLLKKDKYSLAGGLL 142
G S+ P A L P Y + +P ++ + + ++
Sbjct: 120 PPGGGGGGSSDGVGAPPHSAAAAL------PPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
Query: 143 AAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGY---------------AHVNGW 187
G AA+ G G G+ A Q+ G Y A+
Sbjct: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS 233
Query: 188 ANGAYPGSVAAAAA---------AAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHA 238
G PGS AAAAA A+A + A + GG P A A
Sbjct: 234 PRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSA-----------A 282
Query: 239 HPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVA 298
PQP + L SP S+++GY Y G P A A + A A
Sbjct: 283 GGGTPQPTATPTLNQLLTSP-SSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341
Query: 299 AAAAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGG 354
AAAAAAAAS GA S S +R P P + + P GG
Sbjct: 342 AAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGG 397
Score = 43.1 bits (100), Expect = 4e-04
Identities = 60/291 (20%), Positives = 81/291 (27%), Gaps = 46/291 (15%)
Query: 121 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGG 180
+P + S A A GGG +A G + Q L SP A G
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG-- 307
Query: 181 YAHVNGWANGAYPG-------------------------SVAAAAAAAAMMQEAQLAYGQ 215
G+ G Y G + AAAA+ A +
Sbjct: 308 ---YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP 364
Query: 216 HPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGG 275
GG P A P PQP + + Q P S Q GY G
Sbjct: 365 GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ-----QGHGYPG 419
Query: 276 LPYGA----------AAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGS 325
PYG+ A +A GG + + G G + P
Sbjct: 420 QPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQ 479
Query: 326 PPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQ 376
P +S+ P P Y + P ++ S+ S P H Q
Sbjct: 480 QQQPPYSQQP-PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQ 529
Score = 38.1 bits (87), Expect = 0.014
Identities = 67/244 (27%), Positives = 81/244 (33%), Gaps = 53/244 (21%)
Query: 148 GGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQ 207
GG AA A G AA GQ E P +V +Q
Sbjct: 36 GGEAAAAAAAERGEMKAAAGQESEGP---------------------AVGPPQPLGKELQ 74
Query: 208 EAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMS 267
+ + G G G A P + + + P+P AL + G
Sbjct: 75 DGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNA-GPRP-------ALNNNLTEPPGGGGG 126
Query: 268 ASPSGYGGLPYGAAAAAAAAAGGAHQ-----NSAVAAAAAA--------------AAASS 308
S G G P+ AAAA A G Q SAVAAAAAA AA S
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
Query: 309 GALGAL----GSLVKSEPSGSPPAPAHSRAPCPGDLREMISMY-LPAGEGGDPAAAAAAA 363
G G L G S G P +S P Y L + GG P + AAAA
Sbjct: 187 GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA 246
Query: 364 AQSR 367
A S+
Sbjct: 247 AGSK 250
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 64.3 bits (155), Expect = 2e-10
Identities = 85/301 (28%), Positives = 110/301 (36%), Gaps = 59/301 (19%)
Query: 137 LAGGLLAAGAGGGGAAVAMGVGVGVGAA--------------AVGQRLESPGGAAGGGY- 181
L G + G GGGG A G G G GA A+ L P G GGG
Sbjct: 73 LQDGAESNGGGGGGGA---GSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSS 129
Query: 182 -----------------AHVNGWANGAYPGSVAAAAAAAAMMQEAQ-----LAYGQHPGA 219
A+ G G P +VAAAAAA Q LA Q G
Sbjct: 130 DGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGG 189
Query: 220 GGAHPHAHPA-HPHPHHPHAHPHNPQPMHR--YDMGALQY---SPISNSQGYMSASPSGY 273
GG P+A P + H H H +N +R Y A Y SP + G +A+ +G
Sbjct: 190 GGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGS 249
Query: 274 GGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSG-----ALGALGSLVKSEPSGSP-- 326
P +A+A+++++ A Q +AA G A L L+ S S
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQ 309
Query: 327 --PAPAHSRAPCPGDL----REMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQGAGA 380
P +S P G +M S A AAAA+ AQ R H P +G
Sbjct: 310 GYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGG 369
Query: 381 G 381
G
Sbjct: 370 G 370
Score = 54.7 bits (130), Expect = 1e-07
Identities = 90/356 (25%), Positives = 122/356 (34%), Gaps = 59/356 (16%)
Query: 24 GPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISK 83
G GGGGGGG G GGG GA+ + S G A P ++N+ +++
Sbjct: 76 GAESNGGGGGGGAGSGGGPGAEPDLKN-----------SNGN----AGPRPALNNN-LTE 119
Query: 84 RLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY-RPRRKTKTLLKKDKYSLAGGLL 142
G S+ P A L P Y + +P ++ + + ++
Sbjct: 120 PPGGGGGGSSDGVGAPPHSAAAAL------PPPAYGFGQPYGRSPSAVAAAAAAVFHQQH 173
Query: 143 AAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGY---------------AHVNGW 187
G AA+ G G G+ A Q+ G Y A+
Sbjct: 174 GGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS 233
Query: 188 ANGAYPGSVAAAAA---------AAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHA 238
G PGS AAAAA A+A + A + GG P A A
Sbjct: 234 PRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSA-----------A 282
Query: 239 HPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVA 298
PQP + L SP S+++GY Y G P A A + A A
Sbjct: 283 GGGTPQPTATPTLNQLLTSP-SSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341
Query: 299 AAAAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGG 354
AAAAAAAAS GA S S +R P P + + P GG
Sbjct: 342 AAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGG 397
Score = 43.1 bits (100), Expect = 4e-04
Identities = 60/291 (20%), Positives = 81/291 (27%), Gaps = 46/291 (15%)
Query: 121 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGG 180
+P + S A A GGG +A G + Q L SP A G
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARG-- 307
Query: 181 YAHVNGWANGAYPG-------------------------SVAAAAAAAAMMQEAQLAYGQ 215
G+ G Y G + AAAA+ A +
Sbjct: 308 ---YQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSP 364
Query: 216 HPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGG 275
GG P A P PQP + + Q P S Q GY G
Sbjct: 365 GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQ-----QGHGYPG 419
Query: 276 LPYGA----------AAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGS 325
PYG+ A +A GG + + G G + P
Sbjct: 420 QPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQ 479
Query: 326 PPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHYQ 376
P +S+ P P Y + P ++ S+ S P H Q
Sbjct: 480 QQQPPYSQQP-PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQ 529
Score = 38.1 bits (87), Expect = 0.014
Identities = 67/244 (27%), Positives = 81/244 (33%), Gaps = 53/244 (21%)
Query: 148 GGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQ 207
GG AA A G AA GQ E P +V +Q
Sbjct: 36 GGEAAAAAAAERGEMKAAAGQESEGP---------------------AVGPPQPLGKELQ 74
Query: 208 EAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMS 267
+ + G G G A P + + + P+P AL + G
Sbjct: 75 DGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNA-GPRP-------ALNNNLTEPPGGGGG 126
Query: 268 ASPSGYGGLPYGAAAAAAAAAGGAHQ-----NSAVAAAAAA--------------AAASS 308
S G G P+ AAAA A G Q SAVAAAAAA AA S
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
Query: 309 GALGAL----GSLVKSEPSGSPPAPAHSRAPCPGDLREMISMY-LPAGEGGDPAAAAAAA 363
G G L G S G P +S P Y L + GG P + AAAA
Sbjct: 187 GGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAA 246
Query: 364 AQSR 367
A S+
Sbjct: 247 AGSK 250
>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
sapiens]
Length = 941
Score = 59.3 bits (142), Expect = 6e-09
Identities = 27/75 (36%), Positives = 44/75 (58%)
Query: 48 QDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRL 107
+ R +RPMNAF+++ + R + QE+P++ N +K L W V+ EK+ + D AK
Sbjct: 77 EQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEY 136
Query: 108 RALHMKEHPDYKYRP 122
+ MK +P YK+ P
Sbjct: 137 KDAFMKANPGYKWCP 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,757,690
Number of Sequences: 37866
Number of extensions: 1131242
Number of successful extensions: 35093
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 738
Number of HSP's successfully gapped in prelim test: 568
Number of HSP's that attempted gapping in prelim test: 13579
Number of HSP's gapped (non-prelim): 12077
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.