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Search of human proteins with 28195386
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
(317 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 652 0.0
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 347 6e-96
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 342 3e-94
gi|5902108 SRY-box 21 [Homo sapiens] 182 4e-46
gi|4759162 SRY-box 14 [Homo sapiens] 177 1e-44
gi|5902106 SRY-box 15 [Homo sapiens] 144 8e-35
gi|4507225 sex determining region Y [Homo sapiens] 131 9e-31
gi|11967991 SRY-box 17 [Homo sapiens] 129 3e-30
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 129 4e-30
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 123 2e-28
gi|4507161 SRY-box 11 [Homo sapiens] 123 2e-28
gi|8924248 SRY-box 18 [Homo sapiens] 122 3e-28
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 120 1e-27
gi|4557853 transcription factor SOX9 [Homo sapiens] 119 4e-27
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 119 4e-27
gi|13899269 SRY-box 7 [Homo sapiens] 116 2e-26
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 101 8e-22
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 101 8e-22
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 101 8e-22
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 100 2e-21
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 100 2e-21
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 100 2e-21
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 100 2e-21
gi|41406089 SRY-box 13 [Homo sapiens] 98 8e-21
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 87 1e-17
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 87 1e-17
gi|112421108 capicua homolog [Homo sapiens] 84 2e-16
gi|71143137 high-mobility group box 3 [Homo sapiens] 62 9e-10
gi|169168462 PREDICTED: similar to high mobility group box 3 [Ho... 59 6e-09
gi|169168166 PREDICTED: similar to high mobility group box 3 [Ho... 59 6e-09
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 652 bits (1683), Expect = 0.0
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA 60
MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA
Sbjct: 1 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA 60
Query: 61 QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM 120
QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM
Sbjct: 61 QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM 120
Query: 121 KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY 180
KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY
Sbjct: 121 KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY 180
Query: 181 PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM 240
PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM
Sbjct: 181 PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM 240
Query: 241 GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS 300
GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS
Sbjct: 241 GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS 300
Query: 301 GPVPGTAINGTLPLSHM 317
GPVPGTAINGTLPLSHM
Sbjct: 301 GPVPGTAINGTLPLSHM 317
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 347 bits (891), Expect = 6e-96
Identities = 211/399 (52%), Positives = 250/399 (62%), Gaps = 90/399 (22%)
Query: 1 MYNMM-ETELKPPGPQQT---------SGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMV 50
MY+MM ET+L PG Q +GGGGG GG K + DRVKRPMNAFMV
Sbjct: 1 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMV 60
Query: 51 WSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKY 110
WSRGQRRKMAQENPKMHNSEISKRLGAEWK++SE EKRPFIDEAKRLRALHMKEHPDYKY
Sbjct: 61 WSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY 120
Query: 111 RPRRKTKTLMKKDKYTLPGGLLAP----GGNSMASGVGVGAGLGAGVNQRMDS------- 159
RPRRKTKTL+KKDKY+L GGLLA GG ++A GVGVG G A V QR++S
Sbjct: 121 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG-AAAVGQRLESPGGAAGG 179
Query: 160 -YAHMNGWSNGSY-----------SMMQD-QLGYPQHPGL-----NAHGA---------- 191
YAH+NGW+NG+Y +MMQ+ QL Y QHPG +AH A
Sbjct: 180 GYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAH 239
Query: 192 -AQMQPMHRYDVSALQYNSMTSSQTYMNGSPT------YSMSYSQQGTPG---------- 234
QPMHRYD+ ALQY+ +++SQ YM+ SP+ Y + + G
Sbjct: 240 PHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAA 299
Query: 235 ---------MALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPE 285
ALG++GS+VKSE S SPP + +HSRAPC GDLR+MISMYLP E +
Sbjct: 300 AAAAAAASSGALGALGSLVKSEPSGSPP---APAHSRAPC-PGDLREMISMYLPAGEGGD 355
Query: 286 P------AAPSRLH-MSQHYQSGPVPGTAINGTLPLSHM 317
P AA SRLH + QHYQ G +NGT+PL+H+
Sbjct: 356 PAAAAAAAAQSRLHSLPQHYQGA---GAGVNGTVPLTHI 391
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 342 bits (877), Expect = 3e-94
Identities = 194/377 (51%), Positives = 241/377 (63%), Gaps = 66/377 (17%)
Query: 1 MYNMMETELKPP-----------GPQQTSGGG------------GGNSTAAAAGGNQKNS 37
MY+++ETELK P GP G G GG S+ A+GG
Sbjct: 76 MYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTD 135
Query: 38 PDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRL 97
DRVKRPMNAFMVWSRGQRRKMA ENPKMHNSEISKRLGA+WKLL++ EKRPFIDEAKRL
Sbjct: 136 QDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRL 195
Query: 98 RALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGA---GVN 154
RA+HMKE+PDYKYRPRRKTKTL+KKDKY+LP GLL PG + A+ A + GV
Sbjct: 196 RAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVG 255
Query: 155 QRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNA-HGAAQMQPMHRYDVSALQYNSM--T 211
QR+D+Y H+NGW+NG+YS++Q+QLGY Q P +++ + PMHRYD++ LQY+ M
Sbjct: 256 QRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPP 315
Query: 212 SSQTYMN-----------------GSPTYSMSYSQQ---------GTPGMALGSMGSVVK 245
+Q+YMN + + +Y QQ M+LG MGSVVK
Sbjct: 316 GAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVK 375
Query: 246 SEASSSPPVVTSSSHSRAPCQAGDLRDMISMYL-PGAEVPEPAAP---SRLH-MSQHYQS 300
SE SS PP + +SHS+ C GDLRDMISMYL PG + + A+P RLH + QHYQ
Sbjct: 376 SEPSSPPPAI--ASHSQRAC-LGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQG 432
Query: 301 GPVPGTAINGTLPLSHM 317
GTA+NGT+PL+H+
Sbjct: 433 A---GTAVNGTVPLTHI 446
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 182 bits (461), Expect = 4e-46
Identities = 88/120 (73%), Positives = 99/120 (82%), Gaps = 5/120 (4%)
Query: 39 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR 98
D VKRPMNAFMVWSR QRRKMAQENPKMHNSEISKRLGAEWKLL+E+EKRPFIDEAKRLR
Sbjct: 6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65
Query: 99 ALHMKEHPDYKYRPRRKTKTLMKKDKYTLP-----GGLLAPGGNSMASGVGVGAGLGAGV 153
A+HMKEHPDYKYRPRRK KTL+KKDK+ P GG+ ++ +G G+ AG G G+
Sbjct: 66 AMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGL 125
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 177 bits (448), Expect = 1e-44
Identities = 86/112 (76%), Positives = 92/112 (82%)
Query: 39 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR 98
D +KRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSE EKRP+IDEAKRLR
Sbjct: 6 DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLR 65
Query: 99 ALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLG 150
A HMKEHPDYKYRPRRK K L+KKD+Y P L A+G+ VGA G
Sbjct: 66 AQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDG 117
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 144 bits (364), Expect = 8e-35
Identities = 86/170 (50%), Positives = 103/170 (60%), Gaps = 11/170 (6%)
Query: 13 GPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEIS 72
GPQ+ G G + AA G ++VKRPMNAFMVWS QRR+MAQ+NPKMHNSEIS
Sbjct: 28 GPQEREGAG-----SPAAPGTLPL--EKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEIS 80
Query: 73 KRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPG-GL 131
KRLGA+WKLL E EKRPF++EAKRLRA H++++PDYKYRPRRK K+ G G
Sbjct: 81 KRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKSSGAGPSRCGQGRGN 140
Query: 132 LAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYP 181
LA GG G G R SY+ + GSY +L P
Sbjct: 141 LASGGPLWGPGYAT-TQPSRGFGYRPPSYS--TAYLPGSYGSSHCKLEAP 187
>gi|4507225 sex determining region Y [Homo sapiens]
Length = 204
Score = 131 bits (329), Expect = 9e-31
Identities = 75/171 (43%), Positives = 106/171 (61%), Gaps = 20/171 (11%)
Query: 31 GGNQK-NSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRP 89
G N K N DRVKRPMNAF+VWSR QRRKMA ENP+M NSEISK+LG +WK+L+E EK P
Sbjct: 49 GENSKGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWP 108
Query: 90 FIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGL 149
F EA++L+A+H +++P+YKYRPRRK K L K L A + + S V
Sbjct: 109 FFQEAQKLQAMHREKYPNYKYRPRRKAKMLPKNCSL-----LPADPASVLCSEV------ 157
Query: 150 GAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHGAAQMQPMHRY 200
++D+ + + + ++S M+ QLG+ P +NA + Q + + +
Sbjct: 158 ------QLDNRLYRDDCTKATHSRMEHQLGH--LPPINAASSPQQRDRYSH 200
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 129 bits (325), Expect = 3e-30
Identities = 61/140 (43%), Positives = 87/140 (62%), Gaps = 3/140 (2%)
Query: 9 LKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHN 68
L P G + G NS A A + R++RPMNAFMVW++ +R+++AQ+NP +HN
Sbjct: 36 LSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHN 95
Query: 69 SEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP 128
+E+SK LG WK L+ EKRPF++EA+RLR HM++HP+YKYRPRR+ + K +
Sbjct: 96 AELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLK---RVE 152
Query: 129 GGLLAPGGNSMASGVGVGAG 148
GG L A+ +G G
Sbjct: 153 GGFLHGLAEPQAAALGPEGG 172
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 129 bits (323), Expect = 4e-30
Identities = 70/159 (44%), Positives = 94/159 (59%), Gaps = 17/159 (10%)
Query: 32 GNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFI 91
G K+ P VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+LL+E++KRPFI
Sbjct: 96 GASKSKP-HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFI 154
Query: 92 DEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGA 151
+EA+RLR H K+HPDYKY+PRR+ + + PGG GG A
Sbjct: 155 EEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGEAEQGGT-------------A 201
Query: 152 GVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHG 190
+ S AH++ G S M D G P+HP +HG
Sbjct: 202 AIQAHYKS-AHLDHRHPGEGSPMSD--GNPEHPSGQSHG 237
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 123 bits (309), Expect = 2e-28
Identities = 70/152 (46%), Positives = 88/152 (57%), Gaps = 18/152 (11%)
Query: 11 PPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSE 70
PPGP G A G K +KRPMNAFMVWS+ +RRK+ + P MHN+E
Sbjct: 17 PPGPGPAEEG-------AREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAE 69
Query: 71 ISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGG 130
ISKRLG W+LL ++EK PF+ EA+RLR HM ++PDYKYRPR+K+K K + PGG
Sbjct: 70 ISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGG 129
Query: 131 -----LLAPG------GNSMASGVGVGAGLGA 151
L PG G A+G +G G A
Sbjct: 130 SGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAA 161
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 123 bits (308), Expect = 2e-28
Identities = 63/118 (53%), Positives = 80/118 (67%), Gaps = 5/118 (4%)
Query: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94
K + +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK+L ++EK PFI EA
Sbjct: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
Query: 95 KRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAG 152
+RLR HM ++PDYKYRPR+K K D P +P S A G G AG GAG
Sbjct: 103 ERLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSP-EKSAAGGGGGSAGGGAG 155
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 122 bits (307), Expect = 3e-28
Identities = 59/129 (45%), Positives = 84/129 (65%), Gaps = 7/129 (5%)
Query: 11 PPGPQQTSGG----GGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKM 66
PP PQ++ G + A G Q R++RPMNAFMVW++ +R+++AQ+NP +
Sbjct: 51 PPSPQRSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDL 110
Query: 67 HNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYT 126
HN+ +SK LG WK L+ EKRPF++EA+RLR H+++HP+YKYRPRRK + +
Sbjct: 111 HNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQA---RKARR 167
Query: 127 LPGGLLAPG 135
L GLL PG
Sbjct: 168 LEPGLLLPG 176
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 120 bits (302), Expect = 1e-27
Identities = 65/138 (47%), Positives = 84/138 (60%), Gaps = 14/138 (10%)
Query: 14 PQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISK 73
P GGGGG A VKRPMNAFMVW++ RRK+A + P +HN+E+SK
Sbjct: 85 PMPVRGGGGGALKAKP----------HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSK 134
Query: 74 RLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLA 133
LG W+LLSE+EKRPF++EA+RLR H K+HPDYKY+PRR+ K+ + G L
Sbjct: 135 TLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSAKAGHSDSDSGAELG 193
Query: 134 P---GGNSMASGVGVGAG 148
P GG + G+G G
Sbjct: 194 PHPGGGAVYKAEAGLGDG 211
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 119 bits (298), Expect = 4e-27
Identities = 52/84 (61%), Positives = 69/84 (82%), Gaps = 1/84 (1%)
Query: 32 GNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFI 91
G+ KN P VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+LL+E+EKRPF+
Sbjct: 97 GSSKNKP-HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFV 155
Query: 92 DEAKRLRALHMKEHPDYKYRPRRK 115
+EA+RLR H K+HPDYKY+PRR+
Sbjct: 156 EEAERLRVQHKKDHPDYKYQPRRR 179
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 119 bits (298), Expect = 4e-27
Identities = 70/163 (42%), Positives = 90/163 (55%), Gaps = 22/163 (13%)
Query: 12 PGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEI 71
P P T+ GG + K +KRPMNAFMVWS+ +RRK+ +++P MHN+EI
Sbjct: 34 PTPGSTASTGGKADDPSWC----KTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEI 89
Query: 72 SKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT------------- 118
SKRLG WKLL +++K PFI EA+RLR HM ++PDYKYRPR+K K+
Sbjct: 90 SKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASS 149
Query: 119 --LMKKDKYTLPGG---LLAPGGNSMASGVGVGAGLGAGVNQR 156
K DK GG GG S +G G G G G N +
Sbjct: 150 KPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSK 192
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 116 bits (291), Expect = 2e-26
Identities = 54/112 (48%), Positives = 79/112 (70%), Gaps = 1/112 (0%)
Query: 22 GGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKL 81
G + A K S R++RPMNAFMVW++ +R+++A +NP +HN+E+SK LG WK
Sbjct: 26 GQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKA 85
Query: 82 LSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLA 133
L+ ++KRP++DEA+RLR HM+++P+YKYRPRRK K + K PG LL+
Sbjct: 86 LTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRK-KQAKRLCKRVDPGFLLS 136
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 101 bits (252), Expect = 8e-22
Identities = 52/121 (42%), Positives = 72/121 (59%), Gaps = 3/121 (2%)
Query: 4 MMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQEN 63
MM+ L G S G + + G N P +KRPMNAFMVW++ +RRK+ Q
Sbjct: 136 MMDFNLS--GDSDGSAGVSESRIYRESRGRGSNEP-HIKRPMNAFMVWAKDERRKILQAF 192
Query: 64 PKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKD 123
P MHNS ISK LG+ WK ++ EK+P+ +E RL H++++PDYKY+PR K L+
Sbjct: 193 PDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGK 252
Query: 124 K 124
K
Sbjct: 253 K 253
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 101 bits (252), Expect = 8e-22
Identities = 52/121 (42%), Positives = 72/121 (59%), Gaps = 3/121 (2%)
Query: 4 MMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQEN 63
MM+ L G S G + + G N P +KRPMNAFMVW++ +RRK+ Q
Sbjct: 509 MMDFNLS--GDSDGSAGVSESRIYRESRGRGSNEP-HIKRPMNAFMVWAKDERRKILQAF 565
Query: 64 PKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKD 123
P MHNS ISK LG+ WK ++ EK+P+ +E RL H++++PDYKY+PR K L+
Sbjct: 566 PDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGK 625
Query: 124 K 124
K
Sbjct: 626 K 626
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 101 bits (252), Expect = 8e-22
Identities = 52/121 (42%), Positives = 72/121 (59%), Gaps = 3/121 (2%)
Query: 4 MMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQEN 63
MM+ L G S G + + G N P +KRPMNAFMVW++ +RRK+ Q
Sbjct: 522 MMDFNLS--GDSDGSAGVSESRIYRESRGRGSNEP-HIKRPMNAFMVWAKDERRKILQAF 578
Query: 64 PKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKD 123
P MHNS ISK LG+ WK ++ EK+P+ +E RL H++++PDYKY+PR K L+
Sbjct: 579 PDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGK 638
Query: 124 K 124
K
Sbjct: 639 K 639
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 100 bits (248), Expect = 2e-21
Identities = 49/108 (45%), Positives = 70/108 (64%), Gaps = 6/108 (5%)
Query: 22 GGNSTAAA-----AGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLG 76
GG + A A A G + P +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG
Sbjct: 611 GGATVAEARVYRDARGRASSEP-HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILG 669
Query: 77 AEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDK 124
+ WK +S EK+P+ +E RL +H++++P+YKY+PR K ++ K
Sbjct: 670 SRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 717
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 100 bits (248), Expect = 2e-21
Identities = 49/108 (45%), Positives = 70/108 (64%), Gaps = 6/108 (5%)
Query: 22 GGNSTAAA-----AGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLG 76
GG + A A A G + P +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG
Sbjct: 571 GGATVAEARVYRDARGRASSEP-HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILG 629
Query: 77 AEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDK 124
+ WK +S EK+P+ +E RL +H++++P+YKY+PR K ++ K
Sbjct: 630 SRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 677
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 100 bits (248), Expect = 2e-21
Identities = 49/108 (45%), Positives = 70/108 (64%), Gaps = 6/108 (5%)
Query: 22 GGNSTAAA-----AGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLG 76
GG + A A A G + P +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG
Sbjct: 574 GGATVAEARVYRDARGRASSEP-HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILG 632
Query: 77 AEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDK 124
+ WK +S EK+P+ +E RL +H++++P+YKY+PR K ++ K
Sbjct: 633 SRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 680
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 100 bits (248), Expect = 2e-21
Identities = 49/108 (45%), Positives = 70/108 (64%), Gaps = 6/108 (5%)
Query: 22 GGNSTAAA-----AGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLG 76
GG + A A A G + P +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG
Sbjct: 578 GGATVAEARVYRDARGRASSEP-HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILG 636
Query: 77 AEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDK 124
+ WK +S EK+P+ +E RL +H++++P+YKY+PR K ++ K
Sbjct: 637 SRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 684
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 98.2 bits (243), Expect = 8e-21
Identities = 41/88 (46%), Positives = 62/88 (70%)
Query: 34 QKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDE 93
+ + +KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK ++ EK+P+ +E
Sbjct: 417 ESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEE 476
Query: 94 AKRLRALHMKEHPDYKYRPRRKTKTLMK 121
RL H++++PDYKY+PR K +++
Sbjct: 477 QARLSRQHLEKYPDYKYKPRPKRTCIVE 504
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 87.4 bits (215), Expect = 1e-17
Identities = 39/79 (49%), Positives = 56/79 (70%)
Query: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94
K+ VKRPMNAFMVW+R R +A+ NP +N+EIS +LG EW LSE +K+P+ DEA
Sbjct: 331 KDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEA 390
Query: 95 KRLRALHMKEHPDYKYRPR 113
++++ H +E P + Y+PR
Sbjct: 391 QKIKEKHREEFPGWVYQPR 409
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 87.4 bits (215), Expect = 1e-17
Identities = 39/79 (49%), Positives = 56/79 (70%)
Query: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94
K+ VKRPMNAFMVW+R R +A+ NP +N+EIS +LG EW LSE +K+P+ DEA
Sbjct: 331 KDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEA 390
Query: 95 KRLRALHMKEHPDYKYRPR 113
++++ H +E P + Y+PR
Sbjct: 391 QKIKEKHREEFPGWVYQPR 409
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 83.6 bits (205), Expect = 2e-16
Identities = 74/269 (27%), Positives = 118/269 (43%), Gaps = 23/269 (8%)
Query: 11 PPGPQQTSGGGG-----GNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPK 65
PPG ++T +S+ K D ++RPMNAFM++S+ R + Q +P
Sbjct: 165 PPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPN 224
Query: 66 MHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKY--RPRRKTKTLMKKD 123
N +SK LG W L EK+ + D A +++ H K HPD+K+ + R+K+ + K
Sbjct: 225 QDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPT 284
Query: 124 KYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSN-----GSYSMMQDQL 178
L GG SM+ G GV+ + S A S+ GS S ++L
Sbjct: 285 SLGLAGGHKETRERSMSE---TGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERL 341
Query: 179 GYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYS--MSYSQQGTPG-- 234
PG A +H D + ++ ++G +YS +Q G PG
Sbjct: 342 HTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPF 401
Query: 235 MALGSMGSVVKSEASSSPPVV-TSSSHSR 262
A G G++ A+ PP++ T +S S+
Sbjct: 402 AAPGEGGALA---ATGRPPLLPTRASRSQ 427
>gi|71143137 high-mobility group box 3 [Homo sapiens]
Length = 200
Score = 61.6 bits (148), Expect = 9e-10
Identities = 28/81 (34%), Positives = 49/81 (60%)
Query: 29 AAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKR 88
A GG +K P+ KRP + F ++ R K+ NP + +++K+LG W L+++EK+
Sbjct: 81 AKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQ 140
Query: 89 PFIDEAKRLRALHMKEHPDYK 109
P+I +A +L+ + K+ DYK
Sbjct: 141 PYITKAAKLKEKYEKDVADYK 161
Score = 38.5 bits (88), Expect = 0.008
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Query: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKM--HNSEISKRLGAEWKLLSETEKRPFID 92
K P + K M+A+ + + R + ++NP++ + +E SK+ WK +S EK F +
Sbjct: 3 KGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDE 62
Query: 93 EAKRLRALHMKEHPDY 108
AK + + +E DY
Sbjct: 63 MAKADKVRYDREMKDY 78
>gi|169168462 PREDICTED: similar to high mobility group box 3 [Homo
sapiens]
Length = 204
Score = 58.9 bits (141), Expect = 6e-09
Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 5/99 (5%)
Query: 29 AAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKR 88
A GG +K P KRP + F ++S R K+ NP + +++K+LG W L+++EK+
Sbjct: 76 AKGGKKKKDPSAPKRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQ 135
Query: 89 PFIDEAKRLRALHMKEHPDYKYR-----PRRKTKTLMKK 122
P+I + +L+ + K+ D K + +R K KK
Sbjct: 136 PYITKTAKLKEKYEKDVADSKSKGKFDGSKRPAKVAWKK 174
Score = 35.4 bits (80), Expect = 0.067
Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94
K P + K M+A++ + + R + ++NP ++ +E SK+ WK +S EK F + A
Sbjct: 3 KGDPKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMA 61
Query: 95 K 95
K
Sbjct: 62 K 62
>gi|169168166 PREDICTED: similar to high mobility group box 3 [Homo
sapiens]
Length = 204
Score = 58.9 bits (141), Expect = 6e-09
Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 5/99 (5%)
Query: 29 AAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKR 88
A GG +K P KRP + F ++S R K+ NP + +++K+LG W L+++EK+
Sbjct: 76 AKGGKKKKDPSAPKRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQ 135
Query: 89 PFIDEAKRLRALHMKEHPDYKYR-----PRRKTKTLMKK 122
P+I + +L+ + K+ D K + +R K KK
Sbjct: 136 PYITKTAKLKEKYEKDVADSKSKGKFDGSKRPAKVAWKK 174
Score = 35.4 bits (80), Expect = 0.067
Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94
K P + K M+A++ + + R + ++NP ++ +E SK+ WK +S EK F + A
Sbjct: 3 KGDPKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMA 61
Query: 95 K 95
K
Sbjct: 62 K 62
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,342,000
Number of Sequences: 37866
Number of extensions: 729086
Number of successful extensions: 3938
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 3602
Number of HSP's gapped (non-prelim): 373
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.