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Search of human proteins with 27436877
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436877 tripartite motif-containing 59 [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436877 tripartite motif-containing 59 [Homo sapiens] 824 0.0
gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens] 209 5e-54
gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens] 209 5e-54
gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens] 209 5e-54
gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens] 209 5e-54
gi|30023818 tripartite motif protein 50A [Homo sapiens] 107 2e-23
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 101 1e-21
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 97 3e-20
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 95 1e-19
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 92 8e-19
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 92 8e-19
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 92 8e-19
gi|65285121 tripartite motif-containing 73 [Homo sapiens] 91 2e-18
gi|38524612 tripartite motif-containing 74 [Homo sapiens] 89 5e-18
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 89 9e-18
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 89 9e-18
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 88 1e-17
gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens] 86 8e-17
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 85 1e-16
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 85 1e-16
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 82 7e-16
gi|223890259 midline 2 isoform 2 [Homo sapiens] 82 1e-15
gi|223890257 midline 2 isoform 1 [Homo sapiens] 82 1e-15
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 81 2e-15
gi|56605981 tripartite motif-containing 72 [Homo sapiens] 81 2e-15
gi|62865604 tripartite motif protein 31 [Homo sapiens] 80 3e-15
gi|4508005 tripartite motif-containing 26 [Homo sapiens] 79 6e-15
gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapi... 79 7e-15
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 79 7e-15
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 79 7e-15
>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
Length = 403
Score = 824 bits (2129), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR
Sbjct: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHC 120
SITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHC
Sbjct: 61 SITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHC 120
Query: 121 LTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQG 180
LTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQG
Sbjct: 121 LTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQG 180
Query: 181 DKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTI 240
DKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTI
Sbjct: 181 DKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTI 240
Query: 241 SLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNV 300
SLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNV
Sbjct: 241 SLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNV 300
Query: 301 LIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEIT 360
LIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEIT
Sbjct: 301 LIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEIT 360
Query: 361 LIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH 403
LIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH
Sbjct: 361 LIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH 403
>gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]
Length = 410
Score = 209 bits (531), Expect = 5e-54
Identities = 105/306 (34%), Positives = 174/306 (56%), Gaps = 7/306 (2%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
M EE+LTCPIC S+F+DPRVLPCSH FC+ CLE IL+ S +WRP P KCP CR
Sbjct: 4 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPA--PFKCPTCR 61
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH 119
E + TGI SL VN++L+ I+EKY + + P + C H QPLN++CL D +L+CG
Sbjct: 62 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 119
Query: 120 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ 179
C T G+H H ++ AY +E+D + L + D ++ L+ K S +++
Sbjct: 120 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT 179
Query: 180 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT 239
D + V ++F++L TL+QKK L+ + + Q Y P+I ++ I ++Q +
Sbjct: 180 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA 239
Query: 240 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK 298
+ ++ S P+ FL+++ + R+ ++++K+ PLP + P + +W ++ +
Sbjct: 240 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLVDVD 298
Query: 299 NVLIPK 304
+ +P+
Sbjct: 299 KLSLPQ 304
>gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]
Length = 407
Score = 209 bits (531), Expect = 5e-54
Identities = 105/306 (34%), Positives = 174/306 (56%), Gaps = 7/306 (2%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
M EE+LTCPIC S+F+DPRVLPCSH FC+ CLE IL+ S +WRP P KCP CR
Sbjct: 1 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPA--PFKCPTCR 58
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH 119
E + TGI SL VN++L+ I+EKY + + P + C H QPLN++CL D +L+CG
Sbjct: 59 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116
Query: 120 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ 179
C T G+H H ++ AY +E+D + L + D ++ L+ K S +++
Sbjct: 117 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT 176
Query: 180 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT 239
D + V ++F++L TL+QKK L+ + + Q Y P+I ++ I ++Q +
Sbjct: 177 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA 236
Query: 240 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK 298
+ ++ S P+ FL+++ + R+ ++++K+ PLP + P + +W ++ +
Sbjct: 237 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLVDVD 295
Query: 299 NVLIPK 304
+ +P+
Sbjct: 296 KLSLPQ 301
>gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]
Length = 407
Score = 209 bits (531), Expect = 5e-54
Identities = 105/306 (34%), Positives = 174/306 (56%), Gaps = 7/306 (2%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
M EE+LTCPIC S+F+DPRVLPCSH FC+ CLE IL+ S +WRP P KCP CR
Sbjct: 1 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPA--PFKCPTCR 58
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH 119
E + TGI SL VN++L+ I+EKY + + P + C H QPLN++CL D +L+CG
Sbjct: 59 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116
Query: 120 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ 179
C T G+H H ++ AY +E+D + L + D ++ L+ K S +++
Sbjct: 117 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT 176
Query: 180 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT 239
D + V ++F++L TL+QKK L+ + + Q Y P+I ++ I ++Q +
Sbjct: 177 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA 236
Query: 240 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK 298
+ ++ S P+ FL+++ + R+ ++++K+ PLP + P + +W ++ +
Sbjct: 237 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLVDVD 295
Query: 299 NVLIPK 304
+ +P+
Sbjct: 296 KLSLPQ 301
>gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]
Length = 407
Score = 209 bits (531), Expect = 5e-54
Identities = 105/306 (34%), Positives = 174/306 (56%), Gaps = 7/306 (2%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
M EE+LTCPIC S+F+DPRVLPCSH FC+ CLE IL+ S +WRP P KCP CR
Sbjct: 1 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPA--PFKCPTCR 58
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH 119
E + TGI SL VN++L+ I+EKY + + P + C H QPLN++CL D +L+CG
Sbjct: 59 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116
Query: 120 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ 179
C T G+H H ++ AY +E+D + L + D ++ L+ K S +++
Sbjct: 117 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT 176
Query: 180 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT 239
D + V ++F++L TL+QKK L+ + + Q Y P+I ++ I ++Q +
Sbjct: 177 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA 236
Query: 240 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK 298
+ ++ S P+ FL+++ + R+ ++++K+ PLP + P + +W ++ +
Sbjct: 237 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLVDVD 295
Query: 299 NVLIPK 304
+ +P+
Sbjct: 296 KLSLPQ 301
>gi|30023818 tripartite motif protein 50A [Homo sapiens]
Length = 487
Score = 107 bits (266), Expect = 2e-23
Identities = 68/265 (25%), Positives = 123/265 (46%), Gaps = 16/265 (6%)
Query: 5 EEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITE 64
E+ L CPIC +F++P +L C H++C+ CL ++ L L+CP CR +
Sbjct: 11 EDWLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCH---------LDAELRCPVCRQAVD 61
Query: 65 IAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIG 124
G SLP N +L +IE + P+ C H+R PL+++C D++L+CG C +G
Sbjct: 62 ----GSSSLP-NVSLARVIEALRLPGDPEPKVCV-HHRNPLSLFCEKDQELICGLCGLLG 115
Query: 125 QHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEA 184
H HP+ + + Y + K+ L+ +L + LI KL ++
Sbjct: 116 SHQHHPVTPVSTVYSRMKEELAALISELKQEQ-KKVDELIAKLVNNRTRIVNESDVFSWV 174
Query: 185 VLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQE 244
+ + F+EL+ ++++K L + + Q+E+ + RE+ + +
Sbjct: 175 IRREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGN 234
Query: 245 ESPLKFLEKVDDVRQHVQILKQRPL 269
E KF+ K + ++ + RPL
Sbjct: 235 EDHHKFIRKFHSMASRAEMPQARPL 259
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 101 bits (251), Expect = 1e-21
Identities = 76/276 (27%), Positives = 118/276 (42%), Gaps = 38/276 (13%)
Query: 1 MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIPL----- 54
M N E++L CPIC +F P V LPC H CR C +I QA+ ++ R + +
Sbjct: 14 MENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRF 73
Query: 55 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQE---------DHPDIVTCPEHYRQPL 105
+CP CR + G+ L N + II+ Y+QE HP C EH + +
Sbjct: 74 RCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSHP---MCKEHEDEKI 130
Query: 106 NVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQL---TDTHWTDLTH 162
N+YCL + C C G H + LQS + +K + L D T +T
Sbjct: 131 NIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQ 190
Query: 163 LIEKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVG-------NLIN 215
L + + K +S ++ KE + Q F L L++KK L + +
Sbjct: 191 LEDSRRVTKENSHQV----KEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALI 246
Query: 216 QEYTPQIERMKEIREQQLELMALTISLQEESPLKFL 251
Q+Y Q+++ ++ E ++ SL E FL
Sbjct: 247 QQYQEQLDKSTKLVETAIQ------SLDEPGGATFL 276
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 97.1 bits (240), Expect = 3e-20
Identities = 81/285 (28%), Positives = 124/285 (43%), Gaps = 34/285 (11%)
Query: 3 NFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSI 62
N +EE TC IC F DP + C H FCR C+ W P CP CR
Sbjct: 9 NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRR---------CWGQPEGPYACPECR-- 57
Query: 63 TEIAPTGIESLPVNFALRAIIEKYQQEDHPDIV---TCPEHYRQPLNVYCLLDKKLVCGH 119
E++P +L N L + E ++ P V CP H R+PL +C + +L+C
Sbjct: 58 -ELSPQ--RNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAH-REPLAAFCGDELRLLCAA 113
Query: 120 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ 179
C G+H H + LQ A K +K LE L D + E +KM++
Sbjct: 114 CERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLR-KQMQDALLFQAQADETCVLWQKMVE 172
Query: 180 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKE----IREQQLEL 235
++ VL F+ L L ++++ L L +E + R++E + +Q L
Sbjct: 173 SQRQNVLGEFERLRRLLAEEEQQLLQRL-------EEEELEVLPRLREGAAHLGQQSAHL 225
Query: 236 MALTISLQ---EESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEI 277
L L+ + L L+ + D + VQ +K +P PEV P+E+
Sbjct: 226 AELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQP-PEVVPMEL 269
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 95.1 bits (235), Expect = 1e-19
Identities = 77/302 (25%), Positives = 129/302 (42%), Gaps = 34/302 (11%)
Query: 1 MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIP-----L 54
M N E++L CPIC +F P V LPC H CR C ++ QAS + R
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
Query: 55 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDI-------VTCPEHYRQPLNV 107
+CP+CR + G+ L N + II+ Y+QE + + C EH + +N+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINI 136
Query: 108 YCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKL 167
YCL + C C G H + L + Y ++K + L + + +I ++
Sbjct: 137 YCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGN-DRVQAVITQM 195
Query: 168 KEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALC--------DVGNLINQEYT 219
+E E + K+ + Q F+ L LE++K L AL V LI Q Y
Sbjct: 196 EEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQ-YG 254
Query: 220 PQIERMKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQ-----RPLPEVQP 274
+E ++ E ++ S++E +L++ ++ V + + RP P +
Sbjct: 255 DHLEASSKLVESAIQ------SMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYES 308
Query: 275 VE 276
+E
Sbjct: 309 ME 310
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 92.0 bits (227), Expect = 8e-19
Identities = 70/286 (24%), Positives = 124/286 (43%), Gaps = 24/286 (8%)
Query: 1 MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIP-----L 54
M N E++L CPIC +F P V LPC H CR C +I QAS + R
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 55 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQED-----HPDIVTCPEHYRQPLNVYC 109
+CP+CR + G+ L N + II+ Y+QE D C EH + +N+YC
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYC 136
Query: 110 LLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKE 169
L + C C G H + L + ++K + L ++ + +I +L++
Sbjct: 137 LNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN-DRVQGVISQLED 195
Query: 170 QKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTAL-------CDVGNLINQEYTPQI 222
E+ + K+ + + F L LE++K + + + ++Y+ +
Sbjct: 196 TCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHL 255
Query: 223 ERMKEIREQQLELM---ALTISLQEESPLKFLEKVDDVRQHVQILK 265
E + ++ E ++ M + + LQ L L+K+ + + Q+ K
Sbjct: 256 ENVSKLVESGIQFMDEPEMAVFLQNAKTL--LKKISEASKAFQMEK 299
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 92.0 bits (227), Expect = 8e-19
Identities = 70/286 (24%), Positives = 124/286 (43%), Gaps = 24/286 (8%)
Query: 1 MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIP-----L 54
M N E++L CPIC +F P V LPC H CR C +I QAS + R
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 55 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQED-----HPDIVTCPEHYRQPLNVYC 109
+CP+CR + G+ L N + II+ Y+QE D C EH + +N+YC
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYC 136
Query: 110 LLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKE 169
L + C C G H + L + ++K + L ++ + +I +L++
Sbjct: 137 LNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN-DRVQGVISQLED 195
Query: 170 QKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTAL-------CDVGNLINQEYTPQI 222
E+ + K+ + + F L LE++K + + + ++Y+ +
Sbjct: 196 TCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHL 255
Query: 223 ERMKEIREQQLELM---ALTISLQEESPLKFLEKVDDVRQHVQILK 265
E + ++ E ++ M + + LQ L L+K+ + + Q+ K
Sbjct: 256 ENVSKLVESGIQFMDEPEMAVFLQNAKTL--LKKISEASKAFQMEK 299
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 92.0 bits (227), Expect = 8e-19
Identities = 70/286 (24%), Positives = 124/286 (43%), Gaps = 24/286 (8%)
Query: 1 MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIP-----L 54
M N E++L CPIC +F P V LPC H CR C +I QAS + R
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 55 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQED-----HPDIVTCPEHYRQPLNVYC 109
+CP+CR + G+ L N + II+ Y+QE D C EH + +N+YC
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYC 136
Query: 110 LLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKE 169
L + C C G H + L + ++K + L ++ + +I +L++
Sbjct: 137 LNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN-DRVQGVISQLED 195
Query: 170 QKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTAL-------CDVGNLINQEYTPQI 222
E+ + K+ + + F L LE++K + + + ++Y+ +
Sbjct: 196 TCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALIKKYSDHL 255
Query: 223 ERMKEIREQQLELM---ALTISLQEESPLKFLEKVDDVRQHVQILK 265
E + ++ E ++ M + + LQ L L+K+ + + Q+ K
Sbjct: 256 ENVSKLVESGIQFMDEPEMAVFLQNAKTL--LKKISEASKAFQMEK 299
>gi|65285121 tripartite motif-containing 73 [Homo sapiens]
Length = 250
Score = 90.5 bits (223), Expect = 2e-18
Identities = 60/249 (24%), Positives = 113/249 (45%), Gaps = 16/249 (6%)
Query: 5 EEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITE 64
E+ L CPIC +F++ +L C H++C+ CL ++ L ++CP C + +
Sbjct: 11 EDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYH---------LDTKVRCPMCWQVVD 61
Query: 65 IAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIG 124
G SLP N +L +IE + P+ C H+R PL+++C D++L+CG C +G
Sbjct: 62 ----GSSSLP-NVSLAWVIEALRLPGDPEPKVCV-HHRNPLSLFCEKDQELICGLCGLLG 115
Query: 125 QHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEA 184
H HP+ + + + K+ L +L + LI KL + ++
Sbjct: 116 SHQHHPVTPVSTVCSRMKEELAALFSELKQEQ-KKVDELIAKLVKNRTRIVNESDVFSWV 174
Query: 185 VLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQE 244
+ + F+EL ++++K L + + Q+E+ + RE+ + +
Sbjct: 175 IRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGN 234
Query: 245 ESPLKFLEK 253
E +F+ K
Sbjct: 235 EDHHEFIWK 243
>gi|38524612 tripartite motif-containing 74 [Homo sapiens]
Length = 250
Score = 89.4 bits (220), Expect = 5e-18
Identities = 60/249 (24%), Positives = 113/249 (45%), Gaps = 16/249 (6%)
Query: 5 EEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITE 64
E+ L CPIC +F++ +L C H++C+ CL ++ L ++CP C + +
Sbjct: 11 EDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYH---------LDTKVRCPMCWQVVD 61
Query: 65 IAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIG 124
G SLP N +L +IE + P+ C H+R PL+++C D++L+CG C +G
Sbjct: 62 ----GSSSLP-NVSLAWVIEALRLPGDPEPKVCV-HHRNPLSLFCEKDQELICGLCGLLG 115
Query: 125 QHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEA 184
H HP+ + + + K+ L +L + LI KL + ++
Sbjct: 116 SHQHHPVTPVSTVCSRMKEELAALFSELKQEQ-KKVDELIAKLVKNRTRIVNESDVFSWV 174
Query: 185 VLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQE 244
+ + F+EL ++++K L + + Q+E+ + RE+ + +
Sbjct: 175 IRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGN 234
Query: 245 ESPLKFLEK 253
E +F+ K
Sbjct: 235 EDHHEFIWK 243
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 88.6 bits (218), Expect = 9e-18
Identities = 62/241 (25%), Positives = 109/241 (45%), Gaps = 32/241 (13%)
Query: 8 LTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITEIAP 67
L C IC ++ P+VLPC HTFC CL+N + A + L CP CR + +
Sbjct: 20 LVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQS---------LTLSCPVCRQTSILPE 70
Query: 68 TGIESLPVNFALRAIIEKYQQ---------EDHPDIV------TCPEHYRQPLNVYCLLD 112
G+ +L NF + +++E QQ + HP V +CP H + + YC
Sbjct: 71 QGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEAC 130
Query: 113 KKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKS 172
+ +CG C G+H H L+ + K Q+ LE + L L +
Sbjct: 131 ETAMCGEC-RAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGR----LPQLSAAIALVGG 185
Query: 173 HSEKMIQGDKEAVLQY---FKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIR 229
S+++ + EA+ Q F++L L+Q+K++ ++ L + + Q++ +++ +
Sbjct: 186 ISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQ 245
Query: 230 E 230
E
Sbjct: 246 E 246
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 88.6 bits (218), Expect = 9e-18
Identities = 62/241 (25%), Positives = 109/241 (45%), Gaps = 32/241 (13%)
Query: 8 LTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITEIAP 67
L C IC ++ P+VLPC HTFC CL+N + A + L CP CR + +
Sbjct: 20 LVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQS---------LTLSCPVCRQTSILPE 70
Query: 68 TGIESLPVNFALRAIIEKYQQ---------EDHPDIV------TCPEHYRQPLNVYCLLD 112
G+ +L NF + +++E QQ + HP V +CP H + + YC
Sbjct: 71 QGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEAC 130
Query: 113 KKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKS 172
+ +CG C G+H H L+ + K Q+ LE + L L +
Sbjct: 131 ETAMCGEC-RAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGR----LPQLSAAIALVGG 185
Query: 173 HSEKMIQGDKEAVLQY---FKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIR 229
S+++ + EA+ Q F++L L+Q+K++ ++ L + + Q++ +++ +
Sbjct: 186 ISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQ 245
Query: 230 E 230
E
Sbjct: 246 E 246
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 88.2 bits (217), Expect = 1e-17
Identities = 51/165 (30%), Positives = 75/165 (45%), Gaps = 13/165 (7%)
Query: 1 MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIP-----L 54
M N E++L CPIC +F P V LPC H CR C ++ QAS + R
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
Query: 55 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDI-------VTCPEHYRQPLNV 107
+CP+CR + G+ L N + II+ Y+QE + + C EH + +N+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINI 136
Query: 108 YCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQL 152
YCL + C C G H + L + Y ++K LL +L
Sbjct: 137 YCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPRL 181
>gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens]
Length = 241
Score = 85.5 bits (210), Expect = 8e-17
Identities = 58/206 (28%), Positives = 82/206 (39%), Gaps = 37/206 (17%)
Query: 1 MHNFEEELTCPICYSIFEDPRV-LPCSHTFCRNCLENILQASGNFYIWRPLRIP-----L 54
M N E++L CPIC +F P V LPC H CR C +I QAS + R
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 55 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQED-----HPDIVTCPEHYRQPLNVYC 109
+CP+CR + G+ L N + II+ Y+QE D C EH + +N+YC
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYC 136
Query: 110 LLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKE 169
L + C C G H D LTH+ ++ K
Sbjct: 137 LNCEVPTCSLCKVFGAHK--------------------------DCQVAPLTHVFQRQKS 170
Query: 170 QKSHSEKMIQGDKEAVLQYFKELNDT 195
+ S ++ G + V +L DT
Sbjct: 171 ELSDGIAILVGSNDRVQGVISQLEDT 196
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 85.1 bits (209), Expect = 1e-16
Identities = 68/247 (27%), Positives = 111/247 (44%), Gaps = 34/247 (13%)
Query: 3 NFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSI 62
+ +EELTCPIC F+DP + C H FCR CL W P P CP CR
Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHR---------NWAPGGGPFPCPECRH- 54
Query: 63 TEIAPTGIESLPVNFALRAIIEKYQQEDHPDIV--TCPEHYRQPLNVYCLLDKKLVCGHC 120
P+ +L N+AL + EK Q+ + C H+ +PL ++C D++ VC C
Sbjct: 55 ----PSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHW-EPLRLFCEDDQRPVCLVC 109
Query: 121 LTIGQHHGH---PIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKM 177
+H H PID+ +Y ++ Q+ L + HL + + + +
Sbjct: 110 RESQEHQTHAMAPIDEAFESYREKLLKSQRNLV----AKMKKVMHLQDVEVKNATQWKDK 165
Query: 178 IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMA 237
I+ + + F +L++ L +++ FL L N+E + E K++ E L+L
Sbjct: 166 IKSQRMRISTEFSKLHNFLVEEEDLFLQRL-------NKE---EEETKKKLNENTLKLNQ 215
Query: 238 LTISLQE 244
SL++
Sbjct: 216 TIASLKK 222
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 85.1 bits (209), Expect = 1e-16
Identities = 68/308 (22%), Positives = 139/308 (45%), Gaps = 44/308 (14%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
+ N + E +C +C ++P ++ C H FC+ C+ W L CP CR
Sbjct: 20 LENLQVEASCSVCLEYLKEPVIIECGHNFCKACITR---------WWEDLERDFPCPVCR 70
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQ-----EDHPDIVTCPEHYRQPLNVYCLLDKKL 115
+ SL N L +++E +Q D CP+H+ + L+++C D++
Sbjct: 71 KTSR-----YRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHH-EALSLFCYEDQEA 124
Query: 116 VCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSE 175
VC C H H + L A + K+ QK LE L + ++T +++ +
Sbjct: 125 VCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPL-EQKLQEITRCKSSEEKKPGELK 183
Query: 176 KMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKE----IREQ 231
++++ ++ +L+ F+EL+ L+++++ L+ L +E ++R++E + ++
Sbjct: 184 RLVESRRQQILREFEELHRRLDEEQQVLLSRL-------EEEEQDILQRLRENAAHLGDK 236
Query: 232 QLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEI--------YPR--- 280
+ +L L ++ + E + DV+ ++ ++ EV V I +PR
Sbjct: 237 RRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYF 296
Query: 281 -VSKILKE 287
+ KILK+
Sbjct: 297 ALRKILKQ 304
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 82.4 bits (202), Expect = 7e-16
Identities = 58/271 (21%), Positives = 124/271 (45%), Gaps = 32/271 (11%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
+ N + E +C +C ++P ++ C H FC+ C+ W L CP CR
Sbjct: 20 LENLQVEASCSVCLEYLKEPVIIECGHNFCKACITR---------WWEDLERDFPCPVCR 70
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQ-----EDHPDIVTCPEHYRQPLNVYCLLDKKL 115
+ SL N L +++E +Q D CP+H+ + L+++C D++
Sbjct: 71 KTSR-----YRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHH-EALSLFCYEDQEA 124
Query: 116 VCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSE 175
VC C H H + L A + K+ QK LE L + ++T +++ +
Sbjct: 125 VCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPL-EQKLQEITRCKSSEEKKPGELK 183
Query: 176 KMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKE----IREQ 231
++++ ++ +L+ F+EL+ L+++++ L+ L +E ++R++E + ++
Sbjct: 184 RLVESRRQQILREFEELHRRLDEEQQVLLSRL-------EEEEQDILQRLRENAAHLGDK 236
Query: 232 QLELMALTISLQEESPLKFLEKVDDVRQHVQ 262
+ +L L ++ + E + DV+ ++
Sbjct: 237 RRDLAHLAAEVEGKCLQSGFEMLKDVKSTLE 267
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 81.6 bits (200), Expect = 1e-15
Identities = 70/311 (22%), Positives = 135/311 (43%), Gaps = 45/311 (14%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
M E ELTCPIC +FEDP +LPC+H+ C +C IL +S + +CP CR
Sbjct: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQE--DHPDIVTCPEHYRQPLNVYCLLDKKLVCG 118
+ + G++ L N L+ II+++Q+ P+ + R + +++ C
Sbjct: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
Query: 119 HCLTIGQHHGHPIDDLQSAYL----------------KEKDTPQKLLEQLTDTHW---TD 159
C P D +++ K+ T +L+E + DTH T
Sbjct: 141 FC-----EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITC 195
Query: 160 LTHLIEKLKEQKSHSEKMIQGDKEAVLQY----FKELNDTLEQKKKSFLTALCDVGNLIN 215
L H EK+ +++I + V ++ LND E+ K++ +
Sbjct: 196 LDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQT-----------LE 244
Query: 216 QEYTPQIERMKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPV 275
T ++R E+ Q +L+ + ++ + + + +++ + V+I++QR Q +
Sbjct: 245 MNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRK----QMI 300
Query: 276 EIYPRVSKILK 286
+ + +K++K
Sbjct: 301 AVKIKETKVMK 311
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/168 (20%), Positives = 79/168 (47%), Gaps = 2/168 (1%)
Query: 95 VTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTD 154
+TC +H + +N+YC+ D +L+C C +G+H H + L + K K T + L L
Sbjct: 193 ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVK 252
Query: 155 THWTDLTHLIEKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLI 214
+ ++L + + KL + E + +++ EL + ++Q+K+ + + +
Sbjct: 253 RN-SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMK 311
Query: 215 NQEYTPQIERMKEIREQQLELM-ALTISLQEESPLKFLEKVDDVRQHV 261
++ Q+ ++ E+ L+ L+E +FL+ ++ + V
Sbjct: 312 LRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 81.6 bits (200), Expect = 1e-15
Identities = 70/311 (22%), Positives = 135/311 (43%), Gaps = 45/311 (14%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
M E ELTCPIC +FEDP +LPC+H+ C +C IL +S + +CP CR
Sbjct: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQE--DHPDIVTCPEHYRQPLNVYCLLDKKLVCG 118
+ + G++ L N L+ II+++Q+ P+ + R + +++ C
Sbjct: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
Query: 119 HCLTIGQHHGHPIDDLQSAYL----------------KEKDTPQKLLEQLTDTHW---TD 159
C P D +++ K+ T +L+E + DTH T
Sbjct: 141 FC-----EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITC 195
Query: 160 LTHLIEKLKEQKSHSEKMIQGDKEAVLQY----FKELNDTLEQKKKSFLTALCDVGNLIN 215
L H EK+ +++I + V ++ LND E+ K++ +
Sbjct: 196 LDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQT-----------LE 244
Query: 216 QEYTPQIERMKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPV 275
T ++R E+ Q +L+ + ++ + + + +++ + V+I++QR Q +
Sbjct: 245 MNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRK----QMI 300
Query: 276 EIYPRVSKILK 286
+ + +K++K
Sbjct: 301 AVKIKETKVMK 311
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/168 (20%), Positives = 79/168 (47%), Gaps = 2/168 (1%)
Query: 95 VTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTD 154
+TC +H + +N+YC+ D +L+C C +G+H H + L + K K T + L L
Sbjct: 193 ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVK 252
Query: 155 THWTDLTHLIEKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLI 214
+ ++L + + KL + E + +++ EL + ++Q+K+ + + +
Sbjct: 253 RN-SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMK 311
Query: 215 NQEYTPQIERMKEIREQQLELM-ALTISLQEESPLKFLEKVDDVRQHV 261
++ Q+ ++ E+ L+ L+E +FL+ ++ + V
Sbjct: 312 LRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 80.9 bits (198), Expect = 2e-15
Identities = 69/255 (27%), Positives = 113/255 (44%), Gaps = 31/255 (12%)
Query: 3 NFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSI 62
+ +EELTCPIC F+DP + C H FCR CL W P P CP CR
Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHR---------NWAPGGGPFPCPECRH- 54
Query: 63 TEIAPTGIESLPVNFALRAIIEKYQQEDHPDIV--TCPEHYRQPLNVYCLLDKKLVCGHC 120
P+ +L N+AL + EK Q+ + C H+ +PL ++C D++ VC C
Sbjct: 55 ----PSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHW-EPLRLFCEDDQRPVCLVC 109
Query: 121 LTIGQHHGH---PIDDLQSAYLK-----EKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKS 172
+H H PID+ +Y D ++ L +L H L LK Q++
Sbjct: 110 RESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKL---LKSQRN 166
Query: 173 HSEKM--IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERM-KEIR 229
KM + ++ ++ + D ++ ++ T + N + +E ++R+ KE
Sbjct: 167 LVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEE 226
Query: 230 EQQLELMALTISLQE 244
E + +L T+ L +
Sbjct: 227 ETKKKLNENTLKLNQ 241
>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
Length = 477
Score = 80.9 bits (198), Expect = 2e-15
Identities = 49/149 (32%), Positives = 72/149 (48%), Gaps = 23/149 (15%)
Query: 6 EELTCPICYSIFEDPRVLPCSHTFCRNCLENIL---QASGNFYIWRPLRIPLKCPNCRSI 62
+EL+CP+C +F+ P C H+FCR CL + A G + CP C+
Sbjct: 10 QELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGT----------VLCPCCQ-- 57
Query: 63 TEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLT 122
APT ++L N L ++E Q C EH PL++YC D+ LVCG C +
Sbjct: 58 ---APTRPQALSTNLQLARLVEGLAQVPQGH---CEEHL-DPLSIYCEQDRALVCGVCAS 110
Query: 123 IGQHHGHPIDDLQSAYLKEK-DTPQKLLE 150
+G H GH + A+ + K PQ+ L+
Sbjct: 111 LGSHRGHRLLPAAEAHARLKTQLPQQKLQ 139
>gi|62865604 tripartite motif protein 31 [Homo sapiens]
Length = 425
Score = 80.5 bits (197), Expect = 3e-15
Identities = 71/304 (23%), Positives = 128/304 (42%), Gaps = 41/304 (13%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
++ +EE+ CPIC I + P + C H FC C+ I + S F+ KCP C+
Sbjct: 7 VNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFF---------KCPLCK 57
Query: 61 SITEIAPTGIESLPVNFALRAIIEKYQQEDHPDI------VTCPEHYRQPLNVYCLLDKK 114
T + I N LR ++EK Q ++ TCP H ++ + +C D K
Sbjct: 58 --TSVRKNAIR---FNSLLRNLVEKIQALQASEVQSKRKEATCPRH-QEMFHYFCEDDGK 111
Query: 115 LVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDL------THLIEKLK 168
+C C H H + ++ A + Q+ ++ L + H ++
Sbjct: 112 FLCFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFT 171
Query: 169 EQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEI 228
+Q H +K+ +L F+ L+ LE++K L+ + +G+ E T +
Sbjct: 172 DQVEH-------EKQRILTEFELLHQVLEEEKNFLLSRIYWLGH----EGTEAGKHYVAS 220
Query: 229 REQQL-ELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKE 287
E QL +L L SL+ + + + ++D++ V + + + P + + K L E
Sbjct: 221 TEPQLNDLKKLVDSLKTKQNMPPRQLLEDIK--VVLCRSEEFQFLNPTPVPLELEKKLSE 278
Query: 288 EWSR 291
SR
Sbjct: 279 AKSR 282
>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
Length = 539
Score = 79.3 bits (194), Expect = 6e-15
Identities = 70/268 (26%), Positives = 122/268 (45%), Gaps = 26/268 (9%)
Query: 1 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR 60
+ + EEE+TC IC DP + C H FCR+C ++ SG+ + + P K N R
Sbjct: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIR 66
Query: 61 SITEIAP--TGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCG 118
+ ++A IE L V+ + +Q+D E +R+ L+ YC D KL+C
Sbjct: 67 PVWQLASLVENIERLKVDKGRQPGEVTREQQD----AKLCERHREKLHYYCEDDGKLLCV 122
Query: 119 HCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSE--- 175
C +H H +A L EK Q E++ + H + L +K++ ++ E
Sbjct: 123 MCRESREHRPH------TAVLMEK-AAQPHREKILN-HLSTLRRDRDKIQGFQAKGEADI 174
Query: 176 ----KMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQ 231
K +Q ++ ++ F++ + L ++++ L L + QE T E+ K
Sbjct: 175 LAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAK----LEQELTEGREKFKSRGVG 230
Query: 232 QLELMALTIS-LQEESPLKFLEKVDDVR 258
+L +AL IS L+ ++ E + D R
Sbjct: 231 ELARLALVISELEGKAQQPAAELMQDTR 258
>gi|198442878 tripartite motif-containing 17 isoform 3 [Homo
sapiens]
Length = 343
Score = 79.0 bits (193), Expect = 7e-15
Identities = 73/286 (25%), Positives = 130/286 (45%), Gaps = 34/286 (11%)
Query: 5 EEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITE 64
+EE TC IC F DP + C H FCR C++ + + R + CP CR E
Sbjct: 11 QEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR---E 67
Query: 65 IAPTGIESLPVNFALRAIIEKYQQEDHPDIV---TCPEHYRQPLNVYCLLDKKLVCGHCL 121
++P +L N L + E QQ HP + C EH+ +PL ++C D+ +C C
Sbjct: 68 MSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQKDQSPICVVCR 122
Query: 122 TIGQHHGHPI----DDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKM 177
+H H + + +Q LK ++ + L EQ+T T +L + ++ + +
Sbjct: 123 ESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRT-----GNLQAREEQSLAEWQGK 177
Query: 178 IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKE----IREQQL 233
++ +E ++ F+++N L ++++ L AL E R++E + Q
Sbjct: 178 VKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRLRESVACLDRQGH 230
Query: 234 ELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYP 279
L L + L+E S L+ + D+++ L ++ VQ E+ P
Sbjct: 231 SLELLLLQLEERSTQGPLQMLQDMKEP---LSRKNNVSVQCPEVAP 273
>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 79.0 bits (193), Expect = 7e-15
Identities = 73/286 (25%), Positives = 130/286 (45%), Gaps = 34/286 (11%)
Query: 5 EEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITE 64
+EE TC IC F DP + C H FCR C++ + + R + CP CR E
Sbjct: 11 QEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR---E 67
Query: 65 IAPTGIESLPVNFALRAIIEKYQQEDHPDIV---TCPEHYRQPLNVYCLLDKKLVCGHCL 121
++P +L N L + E QQ HP + C EH+ +PL ++C D+ +C C
Sbjct: 68 MSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQKDQSPICVVCR 122
Query: 122 TIGQHHGHPI----DDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKM 177
+H H + + +Q LK ++ + L EQ+T T +L + ++ + +
Sbjct: 123 ESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRT-----GNLQAREEQSLAEWQGK 177
Query: 178 IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKE----IREQQL 233
++ +E ++ F+++N L ++++ L AL E R++E + Q
Sbjct: 178 VKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRLRESVACLDRQGH 230
Query: 234 ELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYP 279
L L + L+E S L+ + D+++ L ++ VQ E+ P
Sbjct: 231 SLELLLLQLEERSTQGPLQMLQDMKEP---LSRKNNVSVQCPEVAP 273
>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 79.0 bits (193), Expect = 7e-15
Identities = 73/286 (25%), Positives = 130/286 (45%), Gaps = 34/286 (11%)
Query: 5 EEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITE 64
+EE TC IC F DP + C H FCR C++ + + R + CP CR E
Sbjct: 11 QEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR---E 67
Query: 65 IAPTGIESLPVNFALRAIIEKYQQEDHPDIV---TCPEHYRQPLNVYCLLDKKLVCGHCL 121
++P +L N L + E QQ HP + C EH+ +PL ++C D+ +C C
Sbjct: 68 MSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQKDQSPICVVCR 122
Query: 122 TIGQHHGHPI----DDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKM 177
+H H + + +Q LK ++ + L EQ+T T +L + ++ + +
Sbjct: 123 ESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRT-----GNLQAREEQSLAEWQGK 177
Query: 178 IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKE----IREQQL 233
++ +E ++ F+++N L ++++ L AL E R++E + Q
Sbjct: 178 VKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRLRESVACLDRQGH 230
Query: 234 ELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYP 279
L L + L+E S L+ + D+++ L ++ VQ E+ P
Sbjct: 231 SLELLLLQLEERSTQGPLQMLQDMKEP---LSRKNNVSVQCPEVAP 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,766,244
Number of Sequences: 37866
Number of extensions: 720455
Number of successful extensions: 3560
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 244
Number of HSP's that attempted gapping in prelim test: 2908
Number of HSP's gapped (non-prelim): 698
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.