BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] (2731 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 5663 0.0 gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 5658 0.0 gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 5636 0.0 gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 3680 0.0 gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 3420 0.0 gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 3295 0.0 gi|153946395 tenascin C precursor [Homo sapiens] 209 4e-53 gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 205 4e-52 gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 148 6e-35 gi|24041035 notch 2 preproprotein [Homo sapiens] 147 1e-34 gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 144 9e-34 gi|148833508 notch1 preproprotein [Homo sapiens] 143 3e-33 gi|4557679 jagged 1 precursor [Homo sapiens] 138 7e-32 gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 137 2e-31 gi|134244285 Notch homolog 3 [Homo sapiens] 135 6e-31 gi|55770876 notch4 preproprotein [Homo sapiens] 135 7e-31 gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 132 6e-30 gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 132 6e-30 gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 130 2e-29 gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 129 5e-29 gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 128 9e-29 gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 127 1e-28 gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 122 4e-27 gi|9506545 delta-like 4 protein precursor [Homo sapiens] 118 7e-26 gi|116235485 delta-notch-like EGF repeat-containing transmembran... 116 3e-25 gi|122937283 6720455I24Rik homolog [Homo sapiens] 116 3e-25 gi|93102379 low density lipoprotein-related protein 1B precursor... 114 1e-24 gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 113 2e-24 gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 113 2e-24 gi|110735443 delta-like 1 [Homo sapiens] 113 2e-24 >gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] Length = 2731 Score = 5663 bits (14691), Expect = 0.0 Identities = 2731/2731 (100%), Positives = 2731/2731 (100%) Query: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ Sbjct: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60 Query: 61 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA 120 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA Sbjct: 61 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA 120 Query: 121 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV 180 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV Sbjct: 121 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV 180 Query: 181 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD 240 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD Sbjct: 181 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD 240 Query: 241 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF 300 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF Sbjct: 241 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF 300 Query: 301 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIVHLFGLTWQLQPVEGELYANGV 360 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIVHLFGLTWQLQPVEGELYANGV Sbjct: 301 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIVHLFGLTWQLQPVEGELYANGV 360 Query: 361 SKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQ 420 SKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQ Sbjct: 361 SKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQ 420 Query: 421 ITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQH 480 ITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQH Sbjct: 421 ITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQH 480 Query: 481 SPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGE 540 SPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGE Sbjct: 481 SPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGE 540 Query: 541 CISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTC 600 CISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTC Sbjct: 541 CISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTC 600 Query: 601 FGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPV 660 FGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPV Sbjct: 601 FGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPV 660 Query: 661 CQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTC 720 CQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTC Sbjct: 661 CQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTC 720 Query: 721 EERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG 780 EERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG Sbjct: 721 EERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG 780 Query: 781 WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPL 840 WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPL Sbjct: 781 WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPL 840 Query: 841 DLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPL 900 DLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPL Sbjct: 841 DLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPL 900 Query: 901 VGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVV 960 VGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVV Sbjct: 901 VGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVV 960 Query: 961 EKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPS 1020 EKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPS Sbjct: 961 EKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPS 1020 Query: 1021 SFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTF 1080 SFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTF Sbjct: 1021 SFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTF 1080 Query: 1081 AWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKH 1140 AWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKH Sbjct: 1081 AWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKH 1140 Query: 1141 HILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALA 1200 HILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALA Sbjct: 1141 HILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALA 1200 Query: 1201 SGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLSD 1260 SGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLSD Sbjct: 1201 SGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLSD 1260 Query: 1261 TNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVD 1320 TNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVD Sbjct: 1261 TNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVD 1320 Query: 1321 RHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNP 1380 RHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNP Sbjct: 1321 RHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNP 1380 Query: 1381 MDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVS 1440 MDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVS Sbjct: 1381 MDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVS 1440 Query: 1441 HSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKM 1500 HSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKM Sbjct: 1441 HSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKM 1500 Query: 1501 KAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHL 1560 KAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHL Sbjct: 1501 KAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHL 1560 Query: 1561 HTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISS 1620 HTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISS Sbjct: 1561 HTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISS 1620 Query: 1621 NGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSF 1680 NGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSF Sbjct: 1621 NGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSF 1680 Query: 1681 HSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGM 1740 HSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGM Sbjct: 1681 HSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGM 1740 Query: 1741 EIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNR 1800 EIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNR Sbjct: 1741 EIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNR 1800 Query: 1801 NLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFI 1860 NLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFI Sbjct: 1801 NLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFI 1860 Query: 1861 QRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLSV 1920 QRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLSV Sbjct: 1861 QRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLSV 1920 Query: 1921 TMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTK 1980 TMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTK Sbjct: 1921 TMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTK 1980 Query: 1981 QARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGL 2040 QARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGL Sbjct: 1981 QARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGL 2040 Query: 2041 VNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTT 2100 VNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTT Sbjct: 2041 VNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTT 2100 Query: 2101 VMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYD 2160 VMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYD Sbjct: 2101 VMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYD 2160 Query: 2161 ADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMDE 2220 ADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMDE Sbjct: 2161 ADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMDE 2220 Query: 2221 DGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADL 2280 DGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADL Sbjct: 2221 DGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADL 2280 Query: 2281 TNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVI 2340 TNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVI Sbjct: 2281 TNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVI 2340 Query: 2341 KEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWK 2400 KEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWK Sbjct: 2341 KEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWK 2400 Query: 2401 QLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLE 2460 QLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLE Sbjct: 2401 QLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLE 2460 Query: 2461 LTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPR 2520 LTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPR Sbjct: 2461 LTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPR 2520 Query: 2521 FAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHY 2580 FAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHY Sbjct: 2521 FAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHY 2580 Query: 2581 FIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIR 2640 FIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIR Sbjct: 2581 FIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIR 2640 Query: 2641 YGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYD 2700 YGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYD Sbjct: 2641 YGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYD 2700 Query: 2701 GYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2731 GYFVLSVEQYLELSDSANNIHFMRQSEIGRR Sbjct: 2701 GYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2731 >gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] Length = 2732 Score = 5658 bits (14679), Expect = 0.0 Identities = 2731/2732 (99%), Positives = 2731/2732 (99%), Gaps = 1/2732 (0%) Query: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ Sbjct: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60 Query: 61 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA 120 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA Sbjct: 61 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA 120 Query: 121 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV 180 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV Sbjct: 121 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV 180 Query: 181 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD 240 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD Sbjct: 181 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD 240 Query: 241 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF 300 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF Sbjct: 241 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF 300 Query: 301 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVI-VHLFGLTWQLQPVEGELYANG 359 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVI VHLFGLTWQLQPVEGELYANG Sbjct: 301 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVEGELYANG 360 Query: 360 VSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRF 419 VSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRF Sbjct: 361 VSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRF 420 Query: 420 QITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQ 479 QITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQ Sbjct: 421 QITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQ 480 Query: 480 HSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNG 539 HSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNG Sbjct: 481 HSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNG 540 Query: 540 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPT 599 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPT Sbjct: 541 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPT 600 Query: 600 CFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLP 659 CFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLP Sbjct: 601 CFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLP 660 Query: 660 VCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPT 719 VCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPT Sbjct: 661 VCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPT 720 Query: 720 CEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQN 779 CEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQN Sbjct: 721 CEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQN 780 Query: 780 GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 839 GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP Sbjct: 781 GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840 Query: 840 LDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTP 899 LDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTP Sbjct: 841 LDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTP 900 Query: 900 LVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIV 959 LVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIV Sbjct: 901 LVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIV 960 Query: 960 VEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIP 1019 VEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIP Sbjct: 961 VEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIP 1020 Query: 1020 SSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYT 1079 SSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYT Sbjct: 1021 SSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYT 1080 Query: 1080 FAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNK 1139 FAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNK Sbjct: 1081 FAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNK 1140 Query: 1140 HHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVAL 1199 HHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVAL Sbjct: 1141 HHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVAL 1200 Query: 1200 ASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLS 1259 ASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLS Sbjct: 1201 ASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLS 1260 Query: 1260 DTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITV 1319 DTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITV Sbjct: 1261 DTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITV 1320 Query: 1320 DRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVN 1379 DRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVN Sbjct: 1321 DRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVN 1380 Query: 1380 PMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISV 1439 PMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISV Sbjct: 1381 PMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISV 1440 Query: 1440 SHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAK 1499 SHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAK Sbjct: 1441 SHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAK 1500 Query: 1500 MKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTH 1559 MKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTH Sbjct: 1501 MKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTH 1560 Query: 1560 LHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTIS 1619 LHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTIS Sbjct: 1561 LHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTIS 1620 Query: 1620 SNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSS 1679 SNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSS Sbjct: 1621 SNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSS 1680 Query: 1680 FHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASG 1739 FHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASG Sbjct: 1681 FHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASG 1740 Query: 1740 MEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHN 1799 MEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHN Sbjct: 1741 MEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHN 1800 Query: 1800 RNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTF 1859 RNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTF Sbjct: 1801 RNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTF 1860 Query: 1860 IQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLS 1919 IQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLS Sbjct: 1861 IQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLS 1920 Query: 1920 VTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYT 1979 VTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYT Sbjct: 1921 VTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYT 1980 Query: 1980 KQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEG 2039 KQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEG Sbjct: 1981 KQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEG 2040 Query: 2040 LVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITT 2099 LVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITT Sbjct: 2041 LVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITT 2100 Query: 2100 TVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEY 2159 TVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEY Sbjct: 2101 TVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEY 2160 Query: 2160 DADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMD 2219 DADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMD Sbjct: 2161 DADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMD 2220 Query: 2220 EDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYAD 2279 EDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYAD Sbjct: 2221 EDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYAD 2280 Query: 2280 LTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQV 2339 LTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQV Sbjct: 2281 LTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQV 2340 Query: 2340 IKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIW 2399 IKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIW Sbjct: 2341 IKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIW 2400 Query: 2400 KQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENL 2459 KQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENL Sbjct: 2401 KQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENL 2460 Query: 2460 ELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQP 2519 ELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQP Sbjct: 2461 ELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQP 2520 Query: 2520 RFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTH 2579 RFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTH Sbjct: 2521 RFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTH 2580 Query: 2580 YFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNI 2639 YFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNI Sbjct: 2581 YFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNI 2640 Query: 2640 RYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGY 2699 RYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGY Sbjct: 2641 RYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGY 2700 Query: 2700 DGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2731 DGYFVLSVEQYLELSDSANNIHFMRQSEIGRR Sbjct: 2701 DGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2732 >gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] Length = 2725 Score = 5636 bits (14621), Expect = 0.0 Identities = 2724/2732 (99%), Positives = 2724/2732 (99%), Gaps = 8/2732 (0%) Query: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ Sbjct: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60 Query: 61 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA 120 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA Sbjct: 61 SRKRKEVEKSTQEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHA 120 Query: 121 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV 180 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV Sbjct: 121 LRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDV 180 Query: 181 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD 240 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD Sbjct: 181 QSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQD 240 Query: 241 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF 300 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF Sbjct: 241 SVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTF 300 Query: 301 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVI-VHLFGLTWQLQPVEGELYANG 359 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVI VHLFGLTWQLQPVEGELYANG Sbjct: 301 SRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVEGELYANG 360 Query: 360 VSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRF 419 VSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRF Sbjct: 361 VSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRF 420 Query: 420 QITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQ 479 QITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQ Sbjct: 421 QITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQ 480 Query: 480 HSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNG 539 HSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNG Sbjct: 481 HSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNG 540 Query: 540 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPT 599 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPT Sbjct: 541 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPT 600 Query: 600 CFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLP 659 CFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLP Sbjct: 601 CFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLP 660 Query: 660 VCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPT 719 VCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPT Sbjct: 661 VCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPT 720 Query: 720 CEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQN 779 CEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQN Sbjct: 721 CEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQN 780 Query: 780 GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 839 GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP Sbjct: 781 GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 840 Query: 840 LDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTP 899 LDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTP Sbjct: 841 LDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTP 900 Query: 900 LVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIV 959 LVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIV Sbjct: 901 LVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIV 960 Query: 960 VEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIP 1019 VEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIP Sbjct: 961 VEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIP 1020 Query: 1020 SSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYT 1079 SSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYT Sbjct: 1021 SSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYT 1080 Query: 1080 FAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNK 1139 FAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNK Sbjct: 1081 FAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNK 1140 Query: 1140 HHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVAL 1199 HHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVAL Sbjct: 1141 HHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVAL 1200 Query: 1200 ASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLS 1259 ASGPDGSVYVGDFNFVRRIFPSGNSVSILEL STSPAHKYYLAMDPVSESLYLS Sbjct: 1201 ASGPDGSVYVGDFNFVRRIFPSGNSVSILEL-------STSPAHKYYLAMDPVSESLYLS 1253 Query: 1260 DTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITV 1319 DTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITV Sbjct: 1254 DTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITV 1313 Query: 1320 DRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVN 1379 DRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVN Sbjct: 1314 DRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVN 1373 Query: 1380 PMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISV 1439 PMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISV Sbjct: 1374 PMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISV 1433 Query: 1440 SHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAK 1499 SHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAK Sbjct: 1434 SHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAK 1493 Query: 1500 MKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTH 1559 MKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTH Sbjct: 1494 MKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTH 1553 Query: 1560 LHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTIS 1619 LHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTIS Sbjct: 1554 LHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTIS 1613 Query: 1620 SNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSS 1679 SNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSS Sbjct: 1614 SNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSS 1673 Query: 1680 FHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASG 1739 FHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASG Sbjct: 1674 FHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASG 1733 Query: 1740 MEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHN 1799 MEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHN Sbjct: 1734 MEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHN 1793 Query: 1800 RNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTF 1859 RNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTF Sbjct: 1794 RNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTF 1853 Query: 1860 IQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLS 1919 IQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLS Sbjct: 1854 IQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLS 1913 Query: 1920 VTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYT 1979 VTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYT Sbjct: 1914 VTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYT 1973 Query: 1980 KQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEG 2039 KQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEG Sbjct: 1974 KQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEG 2033 Query: 2040 LVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITT 2099 LVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITT Sbjct: 2034 LVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITT 2093 Query: 2100 TVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEY 2159 TVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEY Sbjct: 2094 TVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEY 2153 Query: 2160 DADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMD 2219 DADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMD Sbjct: 2154 DADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMD 2213 Query: 2220 EDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYAD 2279 EDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYAD Sbjct: 2214 EDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYAD 2273 Query: 2280 LTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQV 2339 LTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQV Sbjct: 2274 LTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQV 2333 Query: 2340 IKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIW 2399 IKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIW Sbjct: 2334 IKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIW 2393 Query: 2400 KQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENL 2459 KQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENL Sbjct: 2394 KQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENL 2453 Query: 2460 ELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQP 2519 ELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQP Sbjct: 2454 ELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQP 2513 Query: 2520 RFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTH 2579 RFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTH Sbjct: 2514 RFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTH 2573 Query: 2580 YFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNI 2639 YFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNI Sbjct: 2574 YFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNI 2633 Query: 2640 RYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGY 2699 RYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGY Sbjct: 2634 RYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGY 2693 Query: 2700 DGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2731 DGYFVLSVEQYLELSDSANNIHFMRQSEIGRR Sbjct: 2694 DGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2725 >gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] Length = 2769 Score = 3680 bits (9544), Expect = 0.0 Identities = 1753/2801 (62%), Positives = 2155/2801 (76%), Gaps = 102/2801 (3%) Query: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60 M+ + KPY+ L + + + + YTSSS +SE+G+ P++SY+S ETL Y+Q+ R+ Y S+ Sbjct: 1 MDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKAPQKSYSSSETLKAYDQDARLAYGSR 59 Query: 61 SRKRKEVEKSTQEMEFCETSHTLC--------------SGYQTDMHSVSRHGYQLEMGSD 106 K++ E EFC T + Y+TD+ + GY + GSD Sbjct: 60 V---KDIVPQEAE-EFCRTGANFTLRELGLEEVTPPHGTLYRTDI-GLPHCGYSMGAGSD 114 Query: 107 VDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHER-KSDGENGFKFSP 165 D E + SP+H +R+W R +S SSCLSSRANS L+LTDT+HE ++D G + Sbjct: 115 ADMEADTVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHENTETDHPGGLQ--- 171 Query: 166 VCCDMEAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRS 225 N R PPPP HA T + + +SL R + T RS Sbjct: 172 --------------------NHARLRT--PPPPLSHAHTPNQHHAASINSLNRGNFTPRS 209 Query: 226 QPSPA-------APAPPTSTQDSVHLHNSWVLNSNIPLETR------------------- 259 PSPA P Q+ H +W+LNSNIPLETR Sbjct: 210 NPSPAPTDHSLSGEPPAGGAQEPAHAQENWLLNSNIPLETRNLGKQPFLGTLQDNLIEMD 269 Query: 260 --------------HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAF 305 HFLFK G G+S +F S YPLTS+TVYSPPPRPLPRSTF+RPAF Sbjct: 270 ILGASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFARPAF 328 Query: 306 TFNKPYRCCNWKCTALSATAITVTLALLLAY-VIVHLFGLTWQLQPVEGELYANGVSKGN 364 KP + CNWKC ALSA I+ TL +LLAY V +HLFGL W LQP+EG++Y + Sbjct: 329 NLKKPSKYCNWKCAALSAIVISATLVILLAYFVAMHLFGLNWHLQPMEGQMYEITEDTAS 388 Query: 365 RGTESMDTTYSPIGGKVSDKSEKK-----------VFQKGRAIDTGEVDIGAQVMQTIPP 413 D + P GG + ++K F + ID+GE+D+G + Q IPP Sbjct: 389 SWPVPTDVSLYPSGGTGLETPDRKGKGTTEGKPSSFFPEDSFIDSGEIDVGRRASQKIPP 448 Query: 414 GLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSK 473 G FWR Q+ I HP++LKFN+SL K +L+GIYGR+ +PP+HTQFDFV+L+DG++L+ Q+++ Sbjct: 449 GTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEAR 508 Query: 474 GSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCST 533 + T R + S ETGFI+Y+D G W+LAFYNDGK+ E V LTTAIE +D+C + Sbjct: 509 SLEGTPRQSRGTVPPSSHETGFIQYLDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPS 568 Query: 534 NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEE 593 NC GNG+CISG CHCF GFLGPDC R SCPVLC GNG+Y KG C+C GWKG ECDVP Sbjct: 569 NCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTN 628 Query: 594 QCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVN 653 QCID C HGTCI G CIC PGYKGE CEE DC+DP CS G+CV+GECHCS GWGG N Sbjct: 629 QCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTN 688 Query: 654 CETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEE 713 CETP C +QCSGHGTFL D G+CSCDP WTG DCS E+C +CG HGVC G C+CE+ Sbjct: 689 CETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCED 748 Query: 714 GWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLD-AVRDGCPGLCFGNG 772 GW+G C++R+CH C EHG C+DGKCECSPGW G+HCTIAHYLD V++GCPGLC GNG Sbjct: 749 GWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNG 808 Query: 773 RCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPL 832 RCTLD NGWHCVCQ+GW G GC+ ME CGD+ DNDGDGL DC+DPDCC Q C+I+PL Sbjct: 809 RCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPL 868 Query: 833 CQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQV 892 C GSP+PLD+IQ++Q SQ FYDRIKFL+G+DSTH+IP E FD ACVIRGQV Sbjct: 869 CLGSPNPLDIIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQV 928 Query: 893 VAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWL 952 + DGTPLVGVN+SF+++ +G+TISRQDGSFDLV GGIS+IL F+R+PF+ ++ TLWL Sbjct: 929 MTSDGTPLVGVNISFVNNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWL 988 Query: 953 PWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVV 1012 PW++F V+E + M+ ++ PSCD+SNF PNP+V PSPLTSF SC E+G IVPE+Q + Sbjct: 989 PWDRFFVMETIIMRHEENEIPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQAL 1048 Query: 1013 QEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPA 1072 QEEI I +RLSYLSSRTPGYK++LRI LTH TIP ++KVHL VAVEGRL +KWF A Sbjct: 1049 QEEISISGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAA 1108 Query: 1073 AINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNL 1132 A +L Y F W+KTD+Y QKV+GL+EA VSVGYEYE+CPD ILWE+RT VLQG+E+DAS L Sbjct: 1109 APDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKL 1168 Query: 1133 GGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNK 1192 GGWSL+KHH LN QSGI+HKGNGEN F+SQQPPVI +IMGNG +RS++C +CNG A NK Sbjct: 1169 GGWSLDKHHALNIQSGILHKGNGENQFVSQQPPVIGSIMGNGRRRSISCPSCNGLADGNK 1228 Query: 1193 LFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPV 1252 L APVAL G DGS+YVGDFN++RRIFPSGN +ILELRN+D RHS SPAHKYYLA DP+ Sbjct: 1229 LLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLATDPM 1288 Query: 1253 SESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLN 1312 S +++LSD+N+R+V+K+KS V KDL KN EVVAGTGDQCLPFD + CGDGG+A+EA+L Sbjct: 1289 SGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLT 1348 Query: 1313 SPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEW 1372 +PRGITVD+ G IYFVDGTMIR+ID+N +I+T++GSN LTS +PLSCDS MDI+QV LEW Sbjct: 1349 NPRGITVDKFGLIYFVDGTMIRRIDQNGIISTLLGSNDLTSARPLSCDSVMDISQVHLEW 1408 Query: 1373 PTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLE 1432 PTDLA+NPMDNSLYVLDNN+VLQISEN +VRI+AGRP+HCQVPGIDHFL+SKVAIH+TLE Sbjct: 1409 PTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLE 1468 Query: 1433 SARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDG 1492 SA A++VSH+G+L+IAETDE+K+NRI+QVTT+GEI ++AGAP+ CDCK D NCDCFSGD Sbjct: 1469 SATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDD 1528 Query: 1493 GYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQ 1552 GYAKDAK+ PSSLAV DG LYVADLGN+RIR I +N+ LN N+YE++SP DQELY Sbjct: 1529 GYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYL 1588 Query: 1553 FTVNGTHLHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQ 1612 F G HL+T +L T DY+YNFTY +GD+ IT +NGN V++RRD+ GMPLWLVVP GQ Sbjct: 1589 FDTTGKHLYTQSLPTGDYLYNFTYTGDGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQ 1648 Query: 1613 VYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATF 1672 VYW+T+ +N LK V+ QG+ LA+MTY GN+GLLATKSNENGWTT YEYD G LTN TF Sbjct: 1649 VYWVTMGTNSALKSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTF 1708 Query: 1673 PTGEVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSL 1732 PTG+VSSF SD + V+++TS++++V ++TNL+A+ Y L Q+ +++Y + DGSL Sbjct: 1709 PTGQVSSFRSDTDSSVHVQVETSSKDDVTITTNLSASGAFYTLLQDQVRNSYYIGADGSL 1768 Query: 1733 RVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFE 1792 R+ A+GME+ L +EPH+LAG VNPT+GK N++LP ++ NL+EWRQRKEQ +G V+ F Sbjct: 1769 RLLLANGMEVALQTEPHLLAGTVNPTVGKRNVTLPIDNGLNLVEWRQRKEQARGQVTVFG 1828 Query: 1793 RRLRAHNRNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYS 1852 RRLR HNRNLLS+DFD +TRT KIYDDHRKFTLRILYDQ GRP LWSP SR N VN+TYS Sbjct: 1829 RRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPSLWSPSSRLNGVNVTYS 1888 Query: 1853 PSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYD 1912 P G + IQRG +E+MEYDQ+G+I SR +ADGK WSYTYLEKS++LLLHSQR+YIFE+D Sbjct: 1889 PGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYTYLEKSMVLLLHSQRQYIFEFD 1948 Query: 1913 QPDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGR 1972 + D L SVTMP++ R +L+T+ SVGYYRNIY PP+ + S IQD++ DG LL T +LGTGR Sbjct: 1949 KNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEGNASVIQDFTEDGHLLHTFYLGTGR 2008 Query: 1973 RVLYKYTKQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQI 2032 RV+YKY K ++L+E LYDTT+V+ TY+E++G++KTI+L ++GF CTIRYRQ GPLI RQI Sbjct: 2009 RVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYRQIGPLIDRQI 2068 Query: 2033 FRFSEEGLVNARFDYSY-NNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINY 2091 FRF+EEG+VNARFDY+Y N+FRVTSMQAVINETPLPIDLYRY DVSG+TEQFGKF VI Y Sbjct: 2069 FRFTEEGMVNARFDYNYDNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYY 2128 Query: 2092 DLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDAN 2151 D+NQ+ITT VM HTK F A G++ EVQYEI +++ YWMT+QYDN+GR+V +++VG AN Sbjct: 2129 DINQIITTAVMTHTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYAN 2188 Query: 2152 ITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRL 2211 TRY YEYDADGQLQTVS+NDK WRYSYDLNGN++LLS G SARLTPLRYD+RDRITRL Sbjct: 2189 TTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRL 2248 Query: 2212 GEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQ 2271 G++QYKMDEDGFLRQRG DIFEYNS GLL KAYN+A W+V+Y YDGLGRRV+SKSS Sbjct: 2249 GDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKAYNRAGSWSVRYRYDGLGRRVSSKSSHSH 2308 Query: 2272 HLQFFYADLTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLA 2331 HLQFFYADLTNP +VTHLYNH+SSEITSLYYDLQGHL AMELSSG+E+Y+ACDN GTPLA Sbjct: 2309 HLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLA 2368 Query: 2332 VFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRW 2391 VFS G +IK+ILYT YG+IY DT P+FQ+IIG+HGGLYD LTKLVH+G+RDYDV+AGRW Sbjct: 2369 VFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRW 2428 Query: 2392 TTPNHHIWKQLNLL-PKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPG 2450 T+P+H +WK L+ PFNLY F+NN P+ QD+ + TD+ SWL FGFQLHNV+PG Sbjct: 2429 TSPDHELWKHLSSSNVMPFNLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPG 2488 Query: 2451 FPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDG 2510 +PKP+++ +E +YEL+ Q KTQEWD K+ILG+QCE+QKQL+ F++L++ Sbjct: 2489 YPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTIT 2548 Query: 2511 RCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLH 2570 C + K +FA+ SVFGKG+KFA+KDG VT DII VANED RR+AAILN+AHYLENLH Sbjct: 2549 SCQQAPKTKKFASSGSVFGKGVKFALKDGRVTTDIISVANEDGRRVAAILNHAHYLENLH 2608 Query: 2571 FTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQL 2630 FTI+G DTHYF+K G E DL ++G +GGRR LENGVNVTVSQ+ +VLNGRTRR+ DIQL Sbjct: 2609 FTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLENGVNVTVSQINTVLNGRTRRYTDIQL 2668 Query: 2631 QHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQL 2690 Q+GALC N RYGTT++EEK VLE+ARQRAV QAW +EQ+RL+EGEEG+RAWTEGEKQQ+ Sbjct: 2669 QYGALCLNTRYGTTLDEEKARVLELARQRAVRQAWAREQQRLREGEEGLRAWTEGEKQQV 2728 Query: 2691 LSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2731 LSTGRVQGYDG+FV+SVEQY ELSDSANNIHFMRQSE+GRR Sbjct: 2729 LSTGRVQGYDGFFVISVEQYPELSDSANNIHFMRQSEMGRR 2769 >gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] Length = 2699 Score = 3420 bits (8868), Expect = 0.0 Identities = 1620/2754 (58%), Positives = 2086/2754 (75%), Gaps = 78/2754 (2%) Query: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQ-SYNSRETLHEYNQEL-RMNYN 58 M+ + +PY L K + E + YT+SS ++E+ R P Q SY+S ETL ++ + R+ Y Sbjct: 1 MDVKERRPYCSLTKSRREKERRYTNSSADNEECRVPTQKSYSSSETLKAFDHDSSRLLYG 60 Query: 59 SQSRK--RKEVEKSTQE--------MEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVD 108 ++ + +E ++ T++ + CE + + +M + GY + GSD D Sbjct: 61 NRVKDLVHREADEFTRQGQNFTLRQLGVCEPATRRGLAFCAEM-GLPHRGYSISAGSDAD 119 Query: 109 TETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCC 168 TE E SP+HA+R+W RG+KS SSCLSSR+NSAL+LTDT+HE KSD EN Sbjct: 120 TENEAVMSPEHAMRLWGRGVKSGRSSCLSSRSNSALTLTDTEHENKSDSEN--------- 170 Query: 169 DMEAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPS 228 + +S Q T +PLPP A + P+ SL R S+T R S Sbjct: 171 ----------EQPASNQGQSTLQPLPPSHKQHSA-----QHHPSITSLNRNSLTNRRNQS 215 Query: 229 PAAPAPPTS----TQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTS 284 PA PA + T +SV L +SWVL SN+PLE+RHFLFK G+G++ +FS A+ Y + S Sbjct: 216 PAPPAALPAELQTTPESVQLQDSWVLGSNVPLESRHFLFKTGTGTTPLFSTATPGYTMAS 275 Query: 285 NTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVI-VHLFG 343 +VYSPP RPLPR+T SR AF F K + C+WKCTAL A ++V LA+LL+Y I +HLFG Sbjct: 276 GSVYSPPTRPLPRNTLSRSAFKFKKSSKYCSWKCTALCAVGVSVLLAILLSYFIAMHLFG 335 Query: 344 LTWQLQPVEGELYANGVSKGNRGTESMDTTYSPIG--GKVSDKSEKKVFQKGRAIDTGEV 401 L WQLQ E + + NG K N T +T P G GK+ + Q+ ID+GE+ Sbjct: 336 LNWQLQQTENDTFENG--KVNSDTMPTNTVSLPSGDNGKLGGFT-----QENNTIDSGEL 388 Query: 402 DIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKL 461 DIG + +Q IPPG+FWR Q+ I P +LKFNISL KD+L+G+YGR+ +PP+HTQ+DFV+L Sbjct: 389 DIGRRAIQEIPPGIFWRSQLFIDQPQFLKFNISLQKDALIGVYGRKGLPPSHTQYDFVEL 448 Query: 462 MDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVL 521 +DG +L+ ++ + +T+ + R SL E GFI+Y+D G W+LAFYNDGK EQV Sbjct: 449 LDGSRLIAREQRSLLETERAGRQARSVSLHEAGFIQYLDSGIWHLAFYNDGKNAEQVSFN 508 Query: 522 TTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRH 581 T IE + +C NC+GNGEC+SG CHCFPGFLGPDC+R +CPVLC GNG+Y KG C+C Sbjct: 509 TIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFS 568 Query: 582 GWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKG 641 GWKG ECDVP QCIDP C G G CIMG C C GYKGE CEE DC+DP CSNHG+C+ G Sbjct: 569 GWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHG 628 Query: 642 ECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSH 701 ECHCS GWGG NCE +C +QCSGHGT+L ++G C+CDP WTG DCS E+C+++CGSH Sbjct: 629 ECHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSH 688 Query: 702 GVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVR 761 GVC G C+CEEGW GP C +R+CH C EHG CKDGKCECS GW G+HCTI Sbjct: 689 GVCMGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTI-------- 740 Query: 762 DGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC 821 +GCPGLC NGRCTLDQNGWHCVCQ GW G GC+V ME LC D+ DN+GDGL DC+DPDC Sbjct: 741 EGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDC 800 Query: 822 CQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFD 881 C QS+C P C+G PDP D+I QS SQ ++ FYDRI FLIG DSTHVIP E F+ Sbjct: 801 CLQSSCQNQPYCRGLPDPQDIISQSLQSPSQQAAKSFYDRISFLIGSDSTHVIPGESPFN 860 Query: 882 SRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRS 941 A VIRGQV+ DGTPL+GVNVSF H+ +YG+TI+RQDG FDLVA GG S+ L+F+RS Sbjct: 861 KSLASVIRGQVLTADGTPLIGVNVSFFHYPEYGYTITRQDGMFDLVANGGASLTLVFERS 920 Query: 942 PFLPEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPE 1001 PFL + T+W+PWN F V++ + M++ +D PSCD+S F+ PNPI++ SPL++F S PE Sbjct: 921 PFLTQYHTVWIPWNVFYVMDTLVMKKEENDIPSCDLSGFVRPNPIIVSSPLSTFFRSSPE 980 Query: 1002 RGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAV 1061 I+PE QV+ EE IP + ++LSYLSSR GYK++L+I +T S IP ++KVHL VAV Sbjct: 981 DSPIIPETQVLHEETTIPGTDLKLSYLSSRAAGYKSVLKITMTQSIIPFNLMKVHLMVAV 1040 Query: 1062 EGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVV 1121 GRL QKWFPA+ NL YTF W+KTD Y QKV+GL+EA+VSVGYEYE+C D LWE+RT + Sbjct: 1041 VGRLFQKWFPASPNLAYTFIWDKTDAYNQKVYGLSEAVVSVGYEYESCLDLTLWEKRTAI 1100 Query: 1122 LQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVAC 1181 LQG+E+DASN+GGW+L+KHH+L+ Q+GI++KGNGEN FISQQPPV+S+IMGNG +RS++C Sbjct: 1101 LQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENQFISQQPPVVSSIMGNGRRRSISC 1160 Query: 1182 TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSP 1241 +CNG A NKL APVALA G DGS+YVGDFN+VRRIFPSGN S+LEL S++P Sbjct: 1161 PSCNGQADGNKLLAPVALACGIDGSLYVGDFNYVRRIFPSGNVTSVLEL-------SSNP 1213 Query: 1242 AHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCG 1301 AH+YYLA DPV+ LY+SDTNTR++Y+ KSL KDL+KN EVVAGTG+QCLPFD++ CG Sbjct: 1214 AHRYYLATDPVTGDLYVSDTNTRRIYRPKSLTGAKDLTKNAEVVAGTGEQCLPFDEARCG 1273 Query: 1302 DGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDS 1361 DGG+A EA+L SP+G+ VD++G IYFVDGTMIRK+D+N +I+T++GSN LTS +PL+CD+ Sbjct: 1274 DGGKAVEATLMSPKGMAVDKNGLIYFVDGTMIRKVDQNGIISTLLGSNDLTSARPLTCDT 1333 Query: 1362 GMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFL 1421 M I+QVRLEWPTDLA+NPMDNS+YVLDNN+VLQI+ENR+VRI AGRP+HCQVPG++ + Sbjct: 1334 SMHISQVRLEWPTDLAINPMDNSIYVLDNNVVLQITENRQVRIAAGRPMHCQVPGVE-YP 1392 Query: 1422 VSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKI 1481 V K A+ +TLESA AI+VS+SG+L+I ETDE+K+NRI+QVTT+GEI ++AG P++CDCK Sbjct: 1393 VGKHAVQTTLESATAIAVSYSGVLYITETDEKKINRIRQVTTDGEISLVAGIPSECDCKN 1452 Query: 1482 DPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYE 1541 D NCDC+ GYAKDAK+ APSSLA SPDGTLY+ADLGN+RIR +S+N+ LN MN YE Sbjct: 1453 DANCDCYQSGDGYAKDAKLSAPSSLAASPDGTLYIADLGNIRIRAVSKNKPLLNSMNFYE 1512 Query: 1542 IASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGG 1601 +ASP DQELY F +NGTH +T++L+T DY+YNF+Y+++ D+ A+T SNGN++ IRRD Sbjct: 1513 VASPTDQELYIFDINGTHQYTVSLVTGDYLYNFSYSNDNDITAVTDSNGNTLRIRRDPNR 1572 Query: 1602 MPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEY 1661 MP+ +V P QV WLTI +NG LK ++AQG L L TY GN+GLLATKS+E GWTT ++Y Sbjct: 1573 MPVRVVSPDNQVIWLTIGTNGCLKSMTAQGLELVLFTYHGNSGLLATKSDETGWTTFFDY 1632 Query: 1662 DPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNR-ENVLMSTNLTATSTIYILKQENT 1720 D EG LTN TFPTG V++ H D++K V++++S+R E+V +++NL++ + Y + Q+ Sbjct: 1633 DSEGRLTNVTFPTGVVTNLHGDMDKAITVDIESSSREEDVSITSNLSSIDSFYTMVQDQL 1692 Query: 1721 QSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQR 1780 +++Y++ DGSLR+ +ASG++ +EPH+LAG NPT+ K N++LPGE+ NL+EWR R Sbjct: 1693 RNSYQIGYDGSLRIIYASGLDSHYQTEPHVLAGTANPTVAKRNMTLPGENGQNLVEWRFR 1752 Query: 1781 KEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSP 1840 KEQ +G V+ F R+LR + RNLLS+DFD T+T KIYDDHRKF LRI YD +G P LW P Sbjct: 1753 KEQAQGKVNVFGRKLRVNGRNLLSVDFDRTTKTEKIYDDHRKFLLRIAYDTSGHPTLWLP 1812 Query: 1841 VSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLL 1900 S+ VN+TYS +G + IQRGT +EK++YD G+I+SR +ADGK WSYTYLEKS++LL Sbjct: 1813 SSKLMAVNVTYSSTGQIASIQRGTTSEKVDYDGQGRIVSRVFADGKTWSYTYLEKSMVLL 1872 Query: 1901 LHSQRRYIFEYDQPDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDG 1960 LHSQR+YIFEYD D L ++TMPS+ RH++QT+ S+GYYRNIY PP+S+ S I DY+ +G Sbjct: 1873 LHSQRQYIFEYDMWDRLSAITMPSVARHTMQTIRSIGYYRNIYNPPESNASIITDYNEEG 1932 Query: 1961 RLLQTLHLGTGRRVLYKYTKQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIR 2020 LLQT LGT RRVL+KY +Q RLSE+LYD+T+V+ TY+E++GV+KT++L DGFICTIR Sbjct: 1933 LLLQTAFLGTSRRVLFKYRRQTRLSEILYDSTRVSFTYDETAGVLKTVNLQSDGFICTIR 1992 Query: 2021 YRQTGPLIGRQIFRFSEEGLVNARFDYSY-NNFRVTSMQAVINETPLPIDLYRYVDVSGR 2079 YRQ GPLI RQIFRFSE+G+VNARFDYSY N+FRVTSMQ VINETPLPIDLY++ D+SG+ Sbjct: 1993 YRQIGPLIDRQIFRFSEDGMVNARFDYSYDNSFRVTSMQGVINETPLPIDLYQFDDISGK 2052 Query: 2080 TEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRM 2139 EQFGKF VI YD+NQ+I+T VM +TK F A+G++ E+QYEI +++ YW+TIQYDN+GR+ Sbjct: 2053 VEQFGKFGVIYYDINQIISTAVMTYTKHFDAHGRIKEIQYEIFRSLMYWITIQYDNMGRV 2112 Query: 2140 VICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTP 2199 +I++G AN T+Y YEYD DGQLQTV +N+K WRY+YDLNGN++LL+ SARLTP Sbjct: 2113 TKREIKIGPFANTTKYAYEYDVDGQLQTVYLNEKIMWRYNYDLNGNLHLLNPSNSARLTP 2172 Query: 2200 LRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGL 2259 LRYDLRDRITRLG++QY++DEDGFLRQRG +IFEY+S GLL + Y+K SGWTV Y YDGL Sbjct: 2173 LRYDLRDRITRLGDVQYRLDEDGFLRQRGTEIFEYSSKGLLTRVYSKGSGWTVIYRYDGL 2232 Query: 2260 GRRVASKSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEY 2319 GRRV+SK+SLGQHLQFFYADLT P R+TH+YNH+SSEITSLYYDLQGHL AME+SSG+E+ Sbjct: 2233 GRRVSSKTSLGQHLQFFYADLTYPTRITHVYNHSSSEITSLYYDLQGHLFAMEISSGDEF 2292 Query: 2320 YVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHL 2379 Y+A DNTGTPLAVFSS G ++K+I YT YG+IY D+ DFQ++IGFHGGLYD LTKL+H Sbjct: 2293 YIASDNTGTPLAVFSSNGLMLKQIQYTAYGEIYFDSNIDFQLVIGFHGGLYDPLTKLIHF 2352 Query: 2380 GQRDYDVVAGRWTTPNHHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLEL 2439 G+RDYD++AGRWTTP+ IWK++ P PFNLY F NN P KI DV Y TD+ SWL Sbjct: 2353 GERDYDILAGRWTTPDIEIWKRIGKDPAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVT 2412 Query: 2440 FGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLD 2499 FGF LHN +PGFP P+ + E +YEL+ K+Q+WD I G+Q ++ +Q + F+SL Sbjct: 2413 FGFHLHNAIPGFPVPKFDLTEPSYELV----KSQQWDDIPPIFGVQQQVARQAKAFLSLG 2468 Query: 2500 QLPMTPRYNDGRCLEGGKQP--RFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLA 2557 ++ R GG Q FA V S+ GKG+ A+ G V +++ +ANED ++A Sbjct: 2469 KM---AEVQVSRRRAGGAQSWLWFATVKSLIGKGVMLAVSQGRVQTNVLNIANEDCIKVA 2525 Query: 2558 AILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSV 2617 A+LNNA YLENLHFTIEG+DTHYFIK + E DL + T GR+ LENG+NVTVSQ T+V Sbjct: 2526 AVLNNAFYLENLHFTIEGKDTHYFIKTTTPESDLGTLRLTSGRKALENGINVTVSQSTTV 2585 Query: 2618 LNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEE 2677 +NGRTRRFAD+++Q GAL ++RYG T++EEK +LE ARQRA+A+AW +EQ+R+++GEE Sbjct: 2586 VNGRTRRFADVEMQFGALALHVRYGMTLDEEKARILEQARQRALARAWAREQQRVRDGEE 2645 Query: 2678 GIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2731 G R WTEGEK+QLLS G+VQGYDGY+VLSVEQY EL+DSANNI F+RQSEIGRR Sbjct: 2646 GARLWTEGEKRQLLSAGKVQGYDGYYVLSVEQYPELADSANNIQFLRQSEIGRR 2699 >gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] Length = 2765 Score = 3295 bits (8544), Expect = 0.0 Identities = 1589/2778 (57%), Positives = 2055/2778 (73%), Gaps = 103/2778 (3%) Query: 23 YTSSSDESEDGRKPRQ-SYNSRETLHEYNQELRMNYN----------SQSRKRKEVEKST 71 YTSSS +SED R P Q SY+S ETL Y+ + RM+Y S R+ + Sbjct: 22 YTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGNRVTDLIHRESDEFPRQGTNFTL 81 Query: 72 QEMEFCETSHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSE 131 E+ CE S SGY +DM + GY L GSD D++TEG SP+HA+R+W RG+KS Sbjct: 82 AELGICEPSPHR-SGYCSDM-GILHQGYSLSTGSDADSDTEGGMSPEHAIRLWGRGIKSR 139 Query: 132 HSSCLSSRANSALSLTDTDHERKSDGENGFKF--------------------SPVCCDM- 170 SS LSSR NSAL+LTD+D+E KSD ENG PV C M Sbjct: 140 RSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPSLLPSAQLPSSHNPPPVSCQMP 199 Query: 171 --------------------------EAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACT 204 A +G Q S P N + L PP PPPH T Sbjct: 200 LLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPPNHHSQSTLRPPLPPPHNHT 259 Query: 205 CARKPPPAADSLQRRSMTT-RSQPSPAAPAPP--TSTQDSVHLHNSWVLNSNIPLETRHF 261 + +A+SL R S+T RSQ APAP +T +SV L +SWVLNSN+PLETRHF Sbjct: 260 LSHH-HSSANSLNRNSLTNRRSQIHAPAPAPNDLATTPESVQLQDSWVLNSNVPLETRHF 318 Query: 262 LFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTAL 321 LFK SGS+ +FS++S YPLTS TVY+PPPR LPR+TFSR AF KP + C+WKC AL Sbjct: 319 LFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAAL 378 Query: 322 SATAITVTLALLLAYVI-VHLFGLTWQLQPVEGELYANGVSKGNRGTESMDTTYSPIGGK 380 SA A + LA+LLAY I +HL GL WQLQP +G + NG+ G G + D P GGK Sbjct: 379 SAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFNNGIRTGLPGND--DVATMPSGGK 436 Query: 381 VSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSL 440 V K +ID+GE ++G +V Q +PPG+FWR QI I P +LKFNISL KD+L Sbjct: 437 VPWS------LKNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFLKFNISLGKDAL 490 Query: 441 LGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQ-ETGFIEYM 499 G+Y RR +PP+H Q+DF++ +DGK+ K S R I T +Q E F++Y+ Sbjct: 491 FGVYIRRGLPPSHAQYDFMERLDGKE------KWSVVESPRERRSIQTLVQNEAVFVQYL 544 Query: 500 DQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCAR 559 D G W+LAFYNDGK E V T ++ + DC NC+GNGEC+SG CHCFPGFLG DCA+ Sbjct: 545 DVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAK 604 Query: 560 DSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKG 619 +CPVLC GNG+Y KG C C GWKG ECDVP QCIDP+C GHG+CI G C+C GYKG Sbjct: 605 AACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKG 664 Query: 620 EICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCS 679 E CEE DCLDP CS+HG+CV GEC CS GWGG+NCE C +QCSGHGT+L D G+CS Sbjct: 665 EHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCS 724 Query: 680 CDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGK 739 CDP W G DCS E+C+++CG+HGVC G C+CEEGW G C++R CH C EHG CKDGK Sbjct: 725 CDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGK 784 Query: 740 CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVME 799 CEC GW G+HCTI DGCP LC GNGRCTL QN W CVCQ GW G GCNV ME Sbjct: 785 CECREGWNGEHCTI--------DGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAME 836 Query: 800 MLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFY 859 C DN DN+GDGL DC+DPDCC QS C S LC+GS DPLD+IQQ QT + S FY Sbjct: 837 TSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQTDWPAVKS--FY 894 Query: 860 DRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISR 919 DRIK L GKDSTH+IP E F+S +IRGQVV DGTPLVGVNVSF+ + YG+TI+R Sbjct: 895 DRIKLLAGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITR 954 Query: 920 QDGSFDLVAIGGISVILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVVSDPPSCDISN 979 QDG+FDL+A GG S+ L F+R+PF+ ++RT+WLPWN F ++ + M+ + PSCD+S Sbjct: 955 QDGTFDLIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTEENSIPSCDLSG 1014 Query: 980 FISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLL 1039 F+ P+PI++ SPL++F + P + IVPE QV+ EEI +P S V+L YLSSRT GYK+LL Sbjct: 1015 FVRPDPIIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLL 1074 Query: 1040 RILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEAL 1099 +I +T ST+P+ +I+VHL VAVEG L QK F A+ NL YTF W+KTD YGQ+V+GL++A+ Sbjct: 1075 KITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAV 1134 Query: 1100 VSVGYEYETCPDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMF 1159 VSVG+EYETCP ILWE+RT +LQGFE+D SNLGGWSL+KHHILN +SGI+HKG GEN F Sbjct: 1135 VSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQF 1194 Query: 1160 ISQQPPVISTIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIF 1219 ++QQP +I++IMGNG +RS++C +CNG A NKL APVALA G DGS+YVGDFN++RRIF Sbjct: 1195 LTQQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIF 1254 Query: 1220 PSGNSVSILELRNRDTRHSTSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLS 1279 PS N SILELRN++ +HS +PAHKYYLA+DPVS SLY+SDTN+R++Y++KSL TKDL+ Sbjct: 1255 PSRNVTSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLA 1314 Query: 1280 KNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDEN 1339 N EVVAGTG+QCLPFD++ CGDGG+A +A+L SPRGI VD++G +YFVD TMIRK+D+N Sbjct: 1315 GNSEVVAGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQN 1374 Query: 1340 AVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISEN 1399 +I+T++GSN LT+ +PLSCDS MD+ QVRLEWPTDLAVNPMDNSLYVL+NN++L+I+EN Sbjct: 1375 GIISTLLGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITEN 1434 Query: 1400 RRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQ 1459 +V IIAGRP+HCQVPGID+ L SK+AIHS LESA AI++SH+G+L+I ETDE+K+NR++ Sbjct: 1435 HQVSIIAGRPMHCQVPGIDYSL-SKLAIHSALESASAIAISHTGVLYITETDEKKINRLR 1493 Query: 1460 QVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADL 1519 QVTTNGEI ++AGA +DCDCK D NC+C+SGD YA DA + +PSSLAV+PDGT+Y+ADL Sbjct: 1494 QVTTNGEICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADL 1553 Query: 1520 GNVRIRTISRNQAHLNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNSE 1579 GN+RIR +S+N+ LN N YE ASP +QELY F +G H +T++L+T +Y+YNFTY+++ Sbjct: 1554 GNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTGEYLYNFTYSTD 1613 Query: 1580 GDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTY 1639 D+ + +NGNS+ IRRD+ GMP L++P Q+ LT+ +NG LK VS Q L LMTY Sbjct: 1614 NDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTY 1673 Query: 1640 PGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVELDTSNR-E 1698 GNTGLLATKS+E GWTT Y+YD EG LTN T PTG V+S H ++EK ++++ SNR + Sbjct: 1674 DGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSITIDIENSNRDD 1733 Query: 1699 NVLMSTNLTATSTIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPT 1758 +V + TNL++ Y + Q+ +++Y++ +G+LRV +A+GM I SEPH+LAG + PT Sbjct: 1734 DVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPT 1793 Query: 1759 LGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYD 1818 +G+CNISLP E+ N IEWR RKEQ KG V+ F R+LR H RNLLSID+D RT KIYD Sbjct: 1794 IGRCNISLPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDYDRNIRTEKIYD 1853 Query: 1819 DHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKII 1878 DHRKFTLRI+YDQ GRP LW P S VN++Y +G + +QRG +E+ + D+ G+I+ Sbjct: 1854 DHRKFTLRIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQGRIV 1913 Query: 1879 SRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQPDCLLSVTMPSMVRHSLQTMLSVGY 1938 SR +ADGK+WSY+YL+KS++LLL SQR+YIFEYD D LL+VTMPS+ RHS+ T S+GY Sbjct: 1914 SRMFADGKVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVARHSMSTHTSIGY 1973 Query: 1939 YRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYDTTQVTLTY 1998 RNIY PP+S+ S I DYS DGR+L+T LGTGR+V YKY K ++LSE++YD+T VT Y Sbjct: 1974 IRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDSTAVTFGY 2033 Query: 1999 EESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSY--NNFRVTS 2056 +E++GV+K ++L GF CTIRYR+ GPL+ +QI+RFSEEG+VNARFDY+Y N+FR+ S Sbjct: 2034 DETTGVLKMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIAS 2093 Query: 2057 MQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIE 2116 ++ VI+ETPLP+DLYRY ++SG+ E FGKF VI YD+NQ+ITT VM +K F +G++ E Sbjct: 2094 IKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKE 2153 Query: 2117 VQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQW 2176 VQYE+ +++ YWMT+QYD++GR++ ++++G AN T+Y Y+YD DGQLQ+V+VND+ W Sbjct: 2154 VQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQSVAVNDRPTW 2213 Query: 2177 RYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNS 2236 RYSYDLNGN++LL+ G S RL PLRYDLRDRITRLG++QYK+D+DG+L QRG+DIFEYNS Sbjct: 2214 RYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLCQRGSDIFEYNS 2273 Query: 2237 NGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLTNPIRVTHLYNHTSSE 2296 GLL +AYNKASGW+VQY YDG+GRR + K++LG HLQ+FY+DL NP R+TH+YNH++SE Sbjct: 2274 KGLLTRAYNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTRITHVYNHSNSE 2333 Query: 2297 ITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTY 2356 ITSLYYDLQGHL AME SSGEEYYVA DNTGTPLAVFS G +IK++ YT YG+IY+D+ Sbjct: 2334 ITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSN 2393 Query: 2357 PDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLLPKPFNLYSFEN 2416 PDFQ++IGFHGGLYD LTKLVH QRDYDV+AGRWT+P++ +WK + P PFNLY F++ Sbjct: 2394 PDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKEPAPFNLYMFKS 2453 Query: 2417 NYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWD 2476 N P+ D+ Y TD++SWL +FGFQL N++PGFP+ ++ + YEL +++Q + Sbjct: 2454 NNPLSSELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYEL----SESQASE 2509 Query: 2477 PGKTILGIQCELQKQLRNFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAI 2536 G+ I G+Q ++ + F++L+ +T + + + G FA + GKGI FAI Sbjct: 2510 NGQLITGVQQTTERHNQAFMALEGQVITKKLHASIREKAGHW--FATTTPIIGKGIMFAI 2567 Query: 2537 KDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGN 2596 K+G VT + +A+EDSR++A++LNNA+YL+ +H++IEG+DTHYF+K+GS + DLV +G Sbjct: 2568 KEGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHYFVKIGSADGDLVTLGT 2627 Query: 2597 TGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYG---TTVEEEKNHVL 2653 T GR++LE+GVNVTVSQ T ++NGRTRRF +I+ Q+ L +IRYG T++EEK VL Sbjct: 2628 TIGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIRYGLTPDTLDEEKARVL 2687 Query: 2654 EIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLEL 2713 + ARQRA+ AW KEQ++ ++G EG R WTEGEKQQLLSTGRVQGY+GY+VL VEQY EL Sbjct: 2688 DQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQGYEGYYVLPVEQYPEL 2747 Query: 2714 SDSANNIHFMRQSEIGRR 2731 +DS++NI F+RQ+E+G+R Sbjct: 2748 ADSSSNIQFLRQNEMGKR 2765 >gi|153946395 tenascin C precursor [Homo sapiens] Length = 2201 Score = 209 bits (531), Expect = 4e-53 Identities = 107/296 (36%), Positives = 146/296 (49%), Gaps = 27/296 (9%) Query: 530 DCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECD 589 +C NC+ G CI G C C GF G DC++ +CP C G+ G C+C G+ G +C Sbjct: 189 ECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS 248 Query: 590 VPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGW 649 E C P HGTC+ G+C+C G+ G+ C + CL+ C N G CV+ EC C G+ Sbjct: 249 --REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGF 305 Query: 650 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 709 G +C +C C G + G C C+ +TG DC C C + G C G C Sbjct: 306 TGEDCSE--LICPNDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQC 361 Query: 710 QCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCF 769 C+EG+ G C E+ C + C G+C DG+CEC G+ G C CP C Sbjct: 362 VCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELK--------CPNGCS 413 Query: 770 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQ 824 G+GRC NG CVC G++G C+ ++ C ND CV+ C C+Q Sbjct: 414 GHGRCV---NG-QCVCDEGYTGEDCS---QLRC----PNDCHSRGRCVEGKCVCEQ 458 Score = 197 bits (500), Expect = 2e-49 Identities = 96/267 (35%), Positives = 129/267 (48%), Gaps = 20/267 (7%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590 C +C+ G C+ G C C GF G DC CP C G+G G CVC G+ G +C Sbjct: 377 CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 435 Query: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650 + +C + C G C+ G C+C G+KG C + C + C HG CV G C C G+ Sbjct: 436 -QLRCPND-CHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGYT 492 Query: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710 G +C C CS G L G C C+ +TG DC+ C +C G C G C Sbjct: 493 GEDCRDRQ--CPRDCSNRG--LCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCV 548 Query: 711 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 770 C EG++G C+E+ C S C G+C DG+C C G+ G LD + CP C Sbjct: 549 CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTG--------LDCGQHSCPSDCNN 600 Query: 771 NGRCTLDQNGWHCVCQVGWSGTGCNVV 797 G+C + C+C G+SG C+ V Sbjct: 601 LGQCVSGR----CICNEGYSGEDCSEV 623 Score = 196 bits (497), Expect = 3e-49 Identities = 121/382 (31%), Positives = 164/382 (42%), Gaps = 85/382 (22%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGG-NGEYEKGHCVCRHGWKGPECD 589 C ++CN G+C++G C CF G+ G DC+R+ CPV C +G G CVC G+ G +C+ Sbjct: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280 Query: 590 VP-------------EEQCI---------------DPTCFGHGTCIMGVCICVPGYKGEI 621 P E +C+ CF G CI G C C G+ GE Sbjct: 281 KPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGED 340 Query: 622 CEEEDCLDPMCSNHGICVKGECHCSTGWGGVNC-ETPLPV-------------------- 660 C + C C G C +G+C C G+ GV+C E P Sbjct: 341 CGKPTC-PHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFT 399 Query: 661 --------CQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCE 712 C CSGHG + G C CD +TG DCS C +C S G C G C CE Sbjct: 400 GADCGELKCPNGCSGHGRCV--NGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCE 457 Query: 713 EGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRD-GCPGLCFGN 771 +G+ G C + SC + C +HG+C +G C C G+ G+ C RD CP C Sbjct: 458 QGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDC---------RDRQCPRDCSNR 508 Query: 772 GRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQSNCYIS 830 G C Q CVC+ G++G C E+ C ND G CV+ C C + ++ Sbjct: 509 GLCVDGQ----CVCEDGFTGPDC---AELSC----PNDCHGQGRCVNGQCVCHEG--FMG 555 Query: 831 PLCQGSPDPLDLIQQSQTLFSQ 852 C+ P D Q + + Q Sbjct: 556 KDCKEQRCPSDCHGQGRCVDGQ 577 Score = 167 bits (424), Expect = 1e-40 Identities = 99/285 (34%), Positives = 128/285 (44%), Gaps = 33/285 (11%) Query: 540 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEY--EKGHCVCRHGWKGPECDVPEEQCID 597 +C +G C L P R C G G + E CVC GWKGP C PE Sbjct: 139 QCTAGAGCC----LQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPE---CP 191 Query: 598 PTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETP 657 C G CI G CIC G+ GE C + C C++ G CV G C C G+ G +C Sbjct: 192 GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSRE 250 Query: 658 LPVCQEQCSG-HGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWV 716 +C CS HGT + G+C C + G DC+ LC C + G C C C+EG+ Sbjct: 251 --ICPVPCSEEHGTCV--DGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFT 306 Query: 717 GPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL 776 G C E C + C + G+C +G C C G+ G+ C + CP C GRC Sbjct: 307 GEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG--------KPTCPHACHTQGRCEE 358 Query: 777 DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDG---DGLTDCVD 818 Q CVC G++G C+ E C + N G DG +C D Sbjct: 359 GQ----CVCDEGFAGVDCS---EKRCPADCHNRGRCVDGRCECDD 396 Score = 116 bits (291), Expect = 3e-25 Identities = 53/129 (41%), Positives = 66/129 (51%), Gaps = 4/129 (3%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590 C +C+ G C+ G C C GF GPDCA SCP C G G G CVC G+ G +C Sbjct: 501 CPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDC-- 558 Query: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650 +EQ C G G C+ G CIC G+ G C + C C+N G CV G C C+ G+ Sbjct: 559 -KEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSD-CNNLGQCVSGRCICNEGYS 616 Query: 651 GVNCETPLP 659 G +C P Sbjct: 617 GEDCSEVSP 625 Score = 100 bits (250), Expect = 2e-20 Identities = 56/188 (29%), Positives = 78/188 (41%), Gaps = 41/188 (21%) Query: 665 CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERS 724 CSG G F + C C+P W G +CS C C G C G C C++G+ G C + + Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220 Query: 725 CHSHCTEHGQCKDGKCECSPGWEG--------------DHCTIAHYLDAVRDG------- 763 C S C + G+C +G C C G+ G +H T L DG Sbjct: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280 Query: 764 ---CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPD 820 C C+ GRC ++ CVC G++G C+ E++C + DC D Sbjct: 281 KPLCLNNCYNRGRCVENE----CVCDEGFTGEDCS---ELICPN----------DCFDRG 323 Query: 821 CCQQSNCY 828 C CY Sbjct: 324 RCINGTCY 331 Score = 41.6 bits (96), Expect = 0.011 Identities = 15/33 (45%), Positives = 21/33 (63%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCP 563 C ++CN G+C+SG C C G+ G DC+ S P Sbjct: 594 CPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626 >gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] Length = 4242 Score = 205 bits (522), Expect = 4e-52 Identities = 107/266 (40%), Positives = 130/266 (48%), Gaps = 20/266 (7%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590 C +C G G C+ G C C GF GPDC++ SCP C G E G CVC G+ G +C + Sbjct: 218 CPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGM 277 Query: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650 + C G C G C+C PGY GE C C CS G C G C C G+ Sbjct: 278 ---RSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGCSQRGRCKDGRCVCDPGYT 333 Query: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710 G +C T C C G G +D G C C P +TG DCST C +C G C G C Sbjct: 334 GEDCGTRS--CPWDC-GEGGRCVD-GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI 389 Query: 711 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 770 C+ G+ G C RSC C + G+C+DG+C C PG+ G C CP C G Sbjct: 390 CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCG--------SRACPRDCRG 441 Query: 771 NGRCTLDQNGWHCVCQVGWSGTGCNV 796 GRC +NG CVC G+SG C V Sbjct: 442 RGRC---ENG-VCVCNAGYSGEDCGV 463 Score = 199 bits (506), Expect = 3e-50 Identities = 110/323 (34%), Positives = 140/323 (43%), Gaps = 43/323 (13%) Query: 529 DDCST-----NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 583 +DCST +C G G C G C C G+ G DC SCP C G E G CVC G+ Sbjct: 366 EDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGY 425 Query: 584 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 643 G +C + C G G C GVC+C GY GE C C C G C G C Sbjct: 426 TGTDCG---SRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD-CRGRGRCESGRC 481 Query: 644 HCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGV 703 C G+ G +C T C C G G + G C C+P +TG DC + C +C HG+ Sbjct: 482 MCWPGYTGRDCGTR--ACPGDCRGRGRCV--DGRCVCNPGFTGEDCGSRRCPGDCRGHGL 537 Query: 704 CSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDG 763 C G+C C+ G+ G C RSC C GQC DG+C C G+ G+ C + Sbjct: 538 CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQ-------- 589 Query: 764 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQ 823 CP C +G C Q+G C+C G+ C++ C N G C+ Sbjct: 590 CPNDCSQHGVC---QDG-VCICWEGYVSEDCSI---RTCPSNCHGRGR----------CE 632 Query: 824 QSNC-----YISPLCQGSPDPLD 841 + C Y P C P D Sbjct: 633 EGRCLCDPGYTGPTCATRMCPAD 655 Score = 197 bits (501), Expect = 1e-49 Identities = 103/291 (35%), Positives = 127/291 (43%), Gaps = 22/291 (7%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590 C +C G G C SG C C+PG+ G DC +CP C G G G CVC G+ G +C Sbjct: 466 CPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG- 524 Query: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650 +C C GHG C GVC+C GY GE C C C G C+ G C C G+ Sbjct: 525 -SRRC-PGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGYS 581 Query: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710 G +C + C CS HG + GVC C + DCS C C G C G C Sbjct: 582 GEDCG--VRQCPNDCSQHG--VCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCL 637 Query: 711 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 770 C+ G+ GPTC R C + C G+C G C C G+ G+ C + CPG C Sbjct: 638 CDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDC---GQEEPPASACPGGCGP 694 Query: 771 NGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC 821 C Q CVC G+ G C + D G +C D C Sbjct: 695 RELCRAGQ----CVCVEGFRGPDCAI-------QTCPGDCRGRGECHDGSC 734 Score = 195 bits (495), Expect = 6e-49 Identities = 96/269 (35%), Positives = 126/269 (46%), Gaps = 25/269 (9%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590 C +C G G C+ G C C PGF G DC CP C G+G E G CVC G+ G +C Sbjct: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556 Query: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650 + C G G C+ G C+C GY GE C C + CS HG+C G C C G+ Sbjct: 557 ---RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWEGYV 612 Query: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710 +C + C C G G + G C CDP +TG C+T +C +C G C +G+C Sbjct: 613 SEDCS--IRTCPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCL 668 Query: 711 CEEGWVGPTCEER-----SCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCP 765 C G+ G C + +C C C+ G+C C G+ G C I CP Sbjct: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAI--------QTCP 720 Query: 766 GLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 G C G G C + CVC+ G++G C Sbjct: 721 GDCRGRGEC----HDGSCVCKDGYAGEDC 745 Score = 172 bits (437), Expect = 3e-42 Identities = 102/339 (30%), Positives = 134/339 (39%), Gaps = 51/339 (15%) Query: 517 QVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH 576 +V L +EI+++ +C G C P + LC +G ++ Sbjct: 99 EVQALRVRLEILEELVKGLKE--QCTGG---CCPASAQAGTGQTDVRTLCSLHGVFDLSR 153 Query: 577 CVC--RHGWKGPECDVPEEQCIDPT------------CFGHGTCIMGVCICVPGYKGEIC 622 C C GW GP C P + I P+ C G C+ G C+C PGY G C Sbjct: 154 CTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC 213 Query: 623 EEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDP 682 C C G CV+G C C G+ G +C C CS G + G C CDP Sbjct: 214 GWPSCPGD-CQGRGRCVQGVCVCRAGFSGPDCSQRS--CPRGCSQRGR--CEGGRCVCDP 268 Query: 683 KWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCEC 742 +TG DC C C G C G C C G+ G C RSC C++ G+CKDG+C C Sbjct: 269 GYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVC 328 Query: 743 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVM---- 798 PG+ G+ C CP C GRC CVC G++G C+ Sbjct: 329 DPGYTGEDCGTR--------SCPWDCGEGGRCV----DGRCVCWPGYTGEDCSTRTCPRD 376 Query: 799 ----------EMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827 E +C D G+ C DC Q+ C Sbjct: 377 CRGRGRCEDGECICDTGYSGDDCGVRSC-PGDCNQRGRC 414 Score = 143 bits (361), Expect = 2e-33 Identities = 71/202 (35%), Positives = 93/202 (46%), Gaps = 14/202 (6%) Query: 529 DDCSTN-----CNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 583 +DCST C G G+C+ G C C G+ G DC CP C +G + G C+C G+ Sbjct: 552 EDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGY 611 Query: 584 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 643 +C + + C G G C G C+C PGY G C C C G CV+G C Sbjct: 612 VSEDCSI---RTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVC 667 Query: 644 HCSTGWGGVNC---ETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGS 700 C G+GG +C E P C C L AG C C + G DC+ + C +C Sbjct: 668 LCHVGYGGEDCGQEEPPASACPGGCGPRE--LCRAGQCVCVEGFRGPDCAIQTCPGDCRG 725 Query: 701 HGVCSRGICQCEEGWVGPTCEE 722 G C G C C++G+ G C E Sbjct: 726 RGECHDGSCVCKDGYAGEDCGE 747 Score = 118 bits (295), Expect = 9e-26 Identities = 58/171 (33%), Positives = 82/171 (47%), Gaps = 11/171 (6%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590 C +C+ +G C G C C+ G++ DC+ +CP C G G E+G C+C G+ GP C Sbjct: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649 Query: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEED----CLDPMCSNHGICVKGECHCS 646 + C G G C+ GVC+C GY GE C +E+ C +C G+C C Sbjct: 650 ---RMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706 Query: 647 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTME 697 G+ G +C + C C G G G C C + G DC E+ T+E Sbjct: 707 EGFRGPDCA--IQTCPGDCRGRGE--CHDGSCVCKDGYAGEDCGEEVPTIE 753 >gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] Length = 1590 Score = 148 bits (374), Expect = 6e-35 Identities = 89/278 (32%), Positives = 118/278 (42%), Gaps = 30/278 (10%) Query: 562 CPVLCGGNGEYEKGH-CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKG 619 C CG + E + C C+ G+ G C + DP C HG CI +C C+PG+ G Sbjct: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNC---QTALCDPDCKNHGKCIKPNICQCLPGHGG 1354 Query: 620 EICEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVC 678 C+EE C +P C + G C+ G C C G+ G CET VC C G L +C Sbjct: 1355 ATCDEEHC-NPPCQHGGTCLAGNLCTCPYGFVGPRCET--MVCNRHCENGGQ-CLTPDIC 1410 Query: 679 SCDPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQC-K 736 C P W G CST LC C + G C++ C C G+ G C+ CH C G C + Sbjct: 1411 QCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR 1470 Query: 737 DGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 + C C G+ G + C C G+C C C GWSG CN Sbjct: 1471 NNVCVCREGYTGRRFQ--------KSICDPTCMNGGKCVGPST---CSCPSGWSGKRCNT 1519 Query: 797 VMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 834 +C N G +C+ P C + + CQ Sbjct: 1520 ---PICLQKCKNGG----ECIAPSICHCPSSWEGVRCQ 1550 Score = 135 bits (339), Expect = 7e-31 Identities = 91/310 (29%), Positives = 123/310 (39%), Gaps = 31/310 (10%) Query: 531 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEKGH-CVCRHGWKGPEC 588 C C + EC++ + C C PG++G +C C C +G+ K + C C G G C Sbjct: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357 Query: 589 DVPEEQCIDPTCFGHGTCIMG-VCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CHCS 646 D EE C +P C GTC+ G +C C G+ G CE C + C N G C+ + C C Sbjct: 1358 D--EEHC-NPPCQHGGTCLAGNLCTCPYGFVGPRCETMVC-NRHCENGGQCLTPDICQCK 1413 Query: 647 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSR 706 GW G C T L C C G+ C C + G C C C + G C R Sbjct: 1414 PGWYGPTCSTAL--CDPVCLNGGS-CNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR 1470 Query: 707 -GICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHCTIAHYLDAVRDGC 764 +C C EG+ G ++ C C G+C C C GW G C L ++G Sbjct: 1471 NNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNG- 1529 Query: 765 PGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQ 824 G C C C W G C + +C G C+ P+ C Sbjct: 1530 -------GECIAPS---ICHCPSSWEGVRCQI---PICNPKCLYGG----RCIFPNVCSC 1572 Query: 825 SNCYISPLCQ 834 Y C+ Sbjct: 1573 RTEYSGVKCE 1582 Score = 128 bits (321), Expect = 9e-29 Identities = 71/229 (31%), Positives = 99/229 (43%), Gaps = 13/229 (5%) Query: 529 DDCSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGP 586 + C+ C G C++G+ C C GF+GP C C C G+ C C+ GW GP Sbjct: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419 Query: 587 ECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-CH 644 C DP C G+C C+C G+ GE C+ C P C N G C++ C Sbjct: 1420 TCSTA---LCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475 Query: 645 CSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC 704 C G+ G + +C C G + CSC W+G C+T +C +C + G C Sbjct: 1476 CREGYTGRRFQKS--ICDPTCMNGGK-CVGPSTCSCPSGWSGKRCNTPICLQKCKNGGEC 1532 Query: 705 -SRGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEGDHC 751 + IC C W G C+ C+ C G+C C C + G C Sbjct: 1533 IAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581 Score = 119 bits (299), Expect = 3e-26 Identities = 97/346 (28%), Positives = 124/346 (35%), Gaps = 73/346 (21%) Query: 499 MDQGPWYLAFYNDGKKMEQVFVLTT---AIEIMDDCSTNCNGNGECISGHCHCFPGFLGP 555 +D GP + + G M + +LTT + + DDC E C C G Sbjct: 1131 LDSGPEGASVSSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNG---G 1187 Query: 556 DCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----C 611 C D G+G Y CVC G+ G C+V C C G G+ I G C Sbjct: 1188 SCVSDRN--FSPGSGVYL---CVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSC 1241 Query: 612 ICVPGYKGE--------------------ICEEED---------------------CLDP 630 C P K E + +EED C P Sbjct: 1242 DCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYP 1301 Query: 631 MCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 690 + C C G+ G NC+T L C C HG + +C C P G+ C Sbjct: 1302 CGKSRECVAPNICKCKPGYIGSNCQTAL--CDPDCKNHGK-CIKPNICQCLPGHGGATCD 1358 Query: 691 TELCTMECGSHGVCSRG-ICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGWEG 748 E C C G C G +C C G+VGP CE C+ HC GQC C+C PGW G Sbjct: 1359 EEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYG 1418 Query: 749 DHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 C+ A C +C G C C+C G+ G C Sbjct: 1419 PTCSTAL--------CDPVCLNGGSCNKPNT---CLCPNGFFGEHC 1453 Score = 97.8 bits (242), Expect = 1e-19 Identities = 57/199 (28%), Positives = 84/199 (42%), Gaps = 43/199 (21%) Query: 531 CSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGEYEK--------------- 574 C+ +C G+C++ C C PG+ GP C+ C +C G K Sbjct: 1394 CNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHC 1453 Query: 575 ------------GHC------VCRHGWKGPECDVPEEQCIDPTCFGHGTCI-MGVCICVP 615 GHC VCR G+ G ++ DPTC G C+ C C Sbjct: 1454 QNAFCHPPCKNGGHCMRNNVCVCREGYTGRRF---QKSICDPTCMNGGKCVGPSTCSCPS 1510 Query: 616 GYKGEICEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLD 674 G+ G+ C CL C N G C+ CHC + W GV C+ +P+C +C +G + Sbjct: 1511 GWSGKRCNTPICLQK-CKNGGECIAPSICHCPSSWEGVRCQ--IPICNPKCL-YGGRCIF 1566 Query: 675 AGVCSCDPKWTGSDCSTEL 693 VCSC +++G C ++ Sbjct: 1567 PNVCSCRTEYSGVKCEKKI 1585 Score = 40.0 bits (92), Expect = 0.032 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 12/74 (16%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590 C C+GNG+C+ C C P F DC + Y+K + G G CDV Sbjct: 890 CPNLCSGNGQCMEWGCACSPSFSSYDC-----------SDSYDKAPEITELGNAG-FCDV 937 Query: 591 PEEQCIDPTCFGHG 604 + C+ FG G Sbjct: 938 QKYNCMMVRVFGKG 951 Score = 33.1 bits (74), Expect = 3.9 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 4/32 (12%) Query: 764 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 795 CP LC GNG+C W C C +S C+ Sbjct: 890 CPNLCSGNGQCM----EWGCACSPSFSSYDCS 917 >gi|24041035 notch 2 preproprotein [Homo sapiens] Length = 2471 Score = 147 bits (372), Expect = 1e-34 Identities = 98/310 (31%), Positives = 135/310 (43%), Gaps = 46/310 (14%) Query: 528 MDDCSTN-CNGNGEC---ISGH-CHCFPGFLGPDCARDSCP---------VLCGGNGEYE 573 +D+C++N C G C ISG+ CHC + G +C P +C + +E Sbjct: 796 IDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFE 855 Query: 574 KGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTC--IMG--VCICVPGYKGEICEE--EDC 627 C+C GW+G C + ++CI C HG C G +C C PG+ G CEE +DC Sbjct: 856 SYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDC 915 Query: 628 LDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVC-QEQCSGHGTF--LLDAGVCSC 680 L C N G C+ G C C G+ G C+T + C E C GT +++ C C Sbjct: 916 LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKC 975 Query: 681 DPKWTGSDCSTEL--CT-MECGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSH-CT 730 + G C + CT C + G C GI C C G+ G C E C SH C Sbjct: 976 QAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL 1035 Query: 731 EHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQ 786 G C DG +C C G+ G +C L + C G C + C+C Sbjct: 1036 NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCS-----RSPCKNKGTCVQKKAESQCLCP 1090 Query: 787 VGWSGTGCNV 796 GW+G C+V Sbjct: 1091 SGWAGAYCDV 1100 Score = 132 bits (331), Expect = 6e-30 Identities = 96/342 (28%), Positives = 135/342 (39%), Gaps = 64/342 (18%) Query: 528 MDDCSTN-CNGNGECISG----HCHCFPGFLGPDCARD-----SCPVLCGG-NGEYEKGH 576 +D+C++N C CI+G C C G P C S P + G G Sbjct: 683 IDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYK 742 Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--EDCLDP 630 C+C GW G C+V + +C+ C GTC V C C G+KG C+ ++C Sbjct: 743 CLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASN 802 Query: 631 MCSNHGIC---VKG-ECHCSTGWGGVNCETPLPVCQEQ-------CSGHGTFLLDAGVCS 679 C N G C + G CHC + G NC+T L C C F ++ C Sbjct: 803 PCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNF--ESYTCL 860 Query: 680 CDPKWTGSDCS---TELCTMECGSHGVCSRG----ICQCEEGWVGPTCEE--RSCHSH-C 729 C P W G C+ E + C +HG+C +C+C G+ G CEE C ++ C Sbjct: 861 CAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPC 920 Query: 730 TEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVC 785 G C DG C C PG+ GD C + + C G C+ N + C C Sbjct: 921 QNGGSCMDGVNTFSCLCLPGFTGDKCQ-----TDMNECLSEPCKNGGTCSDYVNSYTCKC 975 Query: 786 QVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827 Q G+ G C + + +C + C C Sbjct: 976 QAGFDGVHCE---------------NNINECTESSCFNGGTC 1002 Score = 129 bits (323), Expect = 5e-29 Identities = 90/292 (30%), Positives = 120/292 (41%), Gaps = 63/292 (21%) Query: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKG----------HCVCR 580 C TN NG+ I C C G+ G DC D + E HC C Sbjct: 390 CDTNPL-NGQYI---CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445 Query: 581 HGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSN 634 G+ GP C++ +C C TC+ + C+C+PG+KG CE E +C C N Sbjct: 446 KGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVN 505 Query: 635 HGICV----KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 690 +G CV + +C C G+ G PVCQ +D CS P G+ C Sbjct: 506 NGQCVDKVNRFQCLCPPGFTG-------PVCQ----------IDIDDCSSTPCLNGAKCI 548 Query: 691 TELCTMECGSHGVCSRGICQCEEGWVGPTCEER--SCHSHCTEHGQCKDG----KCECSP 744 EC QC G+ G CEE +C HGQC+DG C C+P Sbjct: 549 DHPNGYEC-----------QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNP 597 Query: 745 GWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 G+ G C+ D + + C +GRC NG+ C CQ G SG C + Sbjct: 598 GYMGAICS-----DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644 Score = 127 bits (320), Expect = 1e-28 Identities = 102/340 (30%), Positives = 125/340 (36%), Gaps = 68/340 (20%) Query: 535 CNGNGECIS-----GHCHCFPGFLGPDCA-RDSCPV-------LCGGNGEYEKGHCVCRH 581 C G C++ G+C C GFLG C RD C C K C C Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94 Query: 582 GWKGPECDVPEEQ--CIDPTCFGHGTCIM-----GVCICVPGYKGEICEEED-CLDPMCS 633 G+ G +C + C GTC M C C G+ G+ C+ D CL C+ Sbjct: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154 Query: 634 NHGICV----KGECHCSTGWGGVNCETPLPVCQ--EQCSGHGTFLLDAGV--CSCDPKWT 685 N C + C C TG+ G CET + C C GT L G C C +T Sbjct: 155 NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214 Query: 686 GSDCST---ELCTMECGSHGVCSRG-----ICQCEEGWVGPTCEER--SCHSH-CTEHGQ 734 G C + C + G C + C C G+ G TCE C +H C G Sbjct: 215 GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGV 274 Query: 735 CKDG----KCECSPGWEGDHCTIAHYLDAVRDGC---PGLCFGNGRCTLDQNGWHCVCQV 787 C DG C C P W G CT D C P C G C G+ CVC Sbjct: 275 CVDGVNTYNCRCPPQWTGQFCT------EDVDECLLQPNACQNGGTCANRNGGYGCVCVN 328 Query: 788 GWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827 GWSG C+ +N+D DC C S C Sbjct: 329 GWSGDDCS--------ENID-------DCAFASCTPGSTC 353 Score = 125 bits (313), Expect = 7e-28 Identities = 97/334 (29%), Positives = 137/334 (41%), Gaps = 56/334 (16%) Query: 528 MDDC-STNCNGNGECI---SGH-CHCFPGFLG-------PDCARDSC--PVLCGGNGEYE 573 +D+C S+ C +G CI +G+ C+C PG G DCA + C + G Y Sbjct: 608 IDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS 667 Query: 574 KGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEIC--EEEDC 627 CVC G+ G C++ ++C C TCI GV CIC G C + +C Sbjct: 668 ---CVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNEC 724 Query: 628 LDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVC-QEQCSGHGTF--LLDAGVCSC 680 L C HG C G +C C GW G+NCE C C GT L++ C+C Sbjct: 725 LSNPCI-HGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTC 783 Query: 681 DPKWTGSDCST---ELCTMECGSHGVCSRGI----CQCEEGWVGPTCEE--RSCHSH-CT 730 + G +C E + C + G C I C C + G C+ C + C Sbjct: 784 KKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCE 843 Query: 731 EHGQCKDG------KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCV 784 CK+ C C+PGW+G CTI + + C +G C Q + C Sbjct: 844 NAAVCKESPNFESYTCLCAPGWQGQRCTI-----DIDECISKPCMNHGLCHNTQGSYMCE 898 Query: 785 CQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVD 818 C G+SG C ++ + N G C+D Sbjct: 899 CPPGFSGMDCEEDIDDCLANPCQNGG----SCMD 928 Score = 121 bits (303), Expect = 1e-26 Identities = 96/345 (27%), Positives = 135/345 (39%), Gaps = 66/345 (19%) Query: 528 MDDCSTN-CNGNGECISG----HCHCFPGFLGPDCARD--SC---PVLCGGNGEYEKGH- 576 +DDC + C G C+ G +C C P + G C D C P C G + Sbjct: 261 IDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNG 320 Query: 577 ---CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEED-CL 628 CVC +GW G +C + C +C TCI V C+C G G +C +D C+ Sbjct: 321 GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACI 380 Query: 629 DPMCSNHGIC----VKGE--CHCSTGWGGVNCETPLPVC----QEQCSGHGTFLLDAGV- 677 C +C + G+ C C G+ G +C + C C G + G Sbjct: 381 SNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAF 440 Query: 678 -CSCDPKWTGSDCSTEL--CTME-CGSHGVCSRGI----CQCEEGWVGPTC--EERSCHS 727 C C + G C ++ C + C + C I C C G+ G C E C S Sbjct: 441 HCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQS 500 Query: 728 H-CTEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWH 782 + C +GQC D +C C PG+ G C I + D C +C NG+ Sbjct: 501 NPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----DIDDCSSTPCLNGAKCIDHPNGYE 555 Query: 783 CVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827 C C G++G +LC +N+DN DPD C C Sbjct: 556 CQCATGFTG--------VLCEENIDN--------CDPDPCHHGQC 584 Score = 120 bits (302), Expect = 1e-26 Identities = 110/373 (29%), Positives = 144/373 (38%), Gaps = 80/373 (21%) Query: 528 MDDCSTN-CNGNGECISG----HCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV---- 578 +++CS++ C G C+ G C C G+ G +C + LC + KG CV Sbjct: 1026 INECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC--QTLVNLCSRSPCKNKGTCVQKKA 1083 Query: 579 -----CRHGWKGPECDVPEEQC----------IDPTCFGHGTCIMG----VCICVPGYKG 619 C GW G CDVP C ++ C G CI C C GY G Sbjct: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143 Query: 620 EICEE--EDCLDPMCSNHGIC---VKG-ECHCSTGWGGVNCETPLPVCQEQ-CSGHGTF- 671 CEE ++C C + C + G C C G+ GVNCE + CQ Q C GT Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCI 1203 Query: 672 -LLDAGVCSCDPKWTGSDCSTELCTMECGSH----GVCSRGI----CQCEEGWVGPTCEE 722 L++ CSC P G C + G H G C I C+C G+ G CE Sbjct: 1204 DLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG 1263 Query: 723 --RSCHSH-CTEHGQ------CKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNG 772 C S+ C+ G D C C + G HC + D CP + C G Sbjct: 1264 DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC------ETFVDVCPQMPCLNGG 1317 Query: 773 RCTLDQN---GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTD--------CVDPDC 821 C + N G+ C C G+SG C + CG G+ C P Sbjct: 1318 TCAVASNMPDGFICRCPPGFSGARC----QSSCGQVKCRKGEQCVHTASGPRCFCPSPRD 1373 Query: 822 CQQSNCYISPLCQ 834 C +S C SP CQ Sbjct: 1374 C-ESGCASSP-CQ 1384 Score = 103 bits (256), Expect = 3e-21 Identities = 96/351 (27%), Positives = 140/351 (39%), Gaps = 68/351 (19%) Query: 526 EIMDDCSTN-CNGNGEC---ISGH-CHCFPGFLGPDCAR--DSC---PVLCGGNGEYEKG 575 E +D+C++N C C I G+ C C PG+ G +C D C P GG Sbjct: 1148 EQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVN 1207 Query: 576 H--CVCRHGWKGPECDVPEEQCI-DPTCFGHGTCIMGV----CICVPGYKGEICEEE--D 626 H C C G +G C+ + C P C G C+ + C C+PG+ GE CE + + Sbjct: 1208 HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINE 1267 Query: 627 CLDPMCSNHGI--CVKGE----CHCSTGWGGVNCETPLPVC-QEQCSGHGTFLL-----D 674 CL CS+ G C++ C C + + G +CET + VC Q C GT + D Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327 Query: 675 AGVCSCDPKWTGSDCSTELCTMECGSHGVC----SRGICQCEEGWVGPTCEERSCHSHCT 730 +C C P ++G+ C + ++C C S C C CE S C Sbjct: 1328 GFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSP---RDCESGCASSPCQ 1384 Query: 731 EHGQCKDGK------CECSPGWEGDHCTIAHYLDAVRDGCPGLCFG--------NGRCTL 776 G C + C+C+P + G C + A P C +G C Sbjct: 1385 HGGSCHPQRQPPYYSCQCAPPFSGSRCEL---YTAPPSTPPATCLSQYCADKARDGVCDE 1441 Query: 777 DQNGWHCVCQVGWSGTGCNVVME---------MLCGDNLDNDGDGLTDCVD 818 N C W G C++ ME + C D ++N D L + V+ Sbjct: 1442 ACNSHAC----QWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVE 1488 >gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) [Homo sapiens] Length = 494 Score = 144 bits (364), Expect = 9e-34 Identities = 107/345 (31%), Positives = 135/345 (39%), Gaps = 91/345 (26%) Query: 535 CNGNGECISGHCHC------------FPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHG 582 C+ G C G C C F +C D +CGG+G+ G+C C+ G Sbjct: 151 CSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAG 210 Query: 583 WKGPECDVP--------EEQCIDPT---CFGHGTCIMGVCIC----VPGYKGEI------ 621 W G +C+ + +C P C GTC+ G C C G G+I Sbjct: 211 WHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCE 270 Query: 622 CEEEDCL-------DPMCSNHGICVKGECHCSTGWGGVNCETP----------LPVCQEQ 664 C+E DC D CS HG C G C C GW G CE P + CQ Sbjct: 271 CDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGS 330 Query: 665 ----CSGHGTFLLDAGVCSCDP----KWTGSDCSTE------LCTMECGSHGVCSRGICQ 710 CSG G + G C+C P + G C + L + CG HG CS G C Sbjct: 331 SDLPCSGRGK--CECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCV 388 Query: 711 CEEGWVGPTC---------EERS---CHSH----CTEHGQCKDGKCECS-PGW--EGDHC 751 CE GW G C EE+S C S C+ G C GKC CS W G+ C Sbjct: 389 CERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYISGEFC 448 Query: 752 TIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 DG +C GNG C+ +C C GW+G C + Sbjct: 449 DCDDRDCDKHDGL--ICTGNGICSCG----NCECWDGWNGNACEI 487 Score = 133 bits (335), Expect = 2e-30 Identities = 110/385 (28%), Positives = 138/385 (35%), Gaps = 99/385 (25%) Query: 535 CNGNGECISGHCHCF---PG-FLGP--DCARDSCPVL----CGGNGEYEKGHCVCRHGWK 584 C+G G C G C C PG F GP +C C C G+G+ + G C C GW Sbjct: 63 CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122 Query: 585 GPECDVP----------EEQC---IDPTCFGHGTCIMGVCIC--------VPGYKGEICE 623 G C P + C D C GTC G C C V G E C+ Sbjct: 123 GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCE-CD 181 Query: 624 EEDCLD----PMCSNHGICVKGECHCSTGWGGVNCE-----TPLPVCQEQCSGHGTFLLD 674 + +C+D +C HG C G C+C GW G CE TP + S G + Sbjct: 182 DRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSN 241 Query: 675 AGVCSC--------DPKWTGSDCSTELCTME---------------CGSHGVCSRGICQC 711 G C C DP D + C + C HG C+ G C C Sbjct: 242 RGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDC 301 Query: 712 EEGWVGPTCEE------------RSCHSH----CTEHGQCKDGKCECSPGWEGDHCTIAH 755 + GW G CE R C C+ G+C+ GKC C P GD Sbjct: 302 KAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYP--PGDRRVYGK 359 Query: 756 YLDAVRDGCPGL----CFGNGRCTLDQNGWHCVCQVGWSG------TGCNVVMEMLCGDN 805 + C L C G+G C+ + CVC+ GW G CN+ E N Sbjct: 360 TCECDDRRCEDLDGVVCGGHGTCSCGR----CVCERGWFGKLCQHPRKCNMTEEQ--SKN 413 Query: 806 LDNDGDGLTDCVDPDCCQQSNCYIS 830 L DG+ C C C S Sbjct: 414 LCESADGIL-CSGKGSCHCGKCICS 437 Score = 108 bits (270), Expect = 7e-23 Identities = 99/351 (28%), Positives = 126/351 (35%), Gaps = 94/351 (26%) Query: 565 LCGGNGEYEKGHCVCR----HGWKGPECDVPEEQC---IDPTCFGHGTCIMGVCICVPGY 617 LC G G + G C+C + GP C+ E C TC GHG C G C C G+ Sbjct: 62 LCHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGW 121 Query: 618 KGEICEE---------------EDCLDPMCSNHGICVKGECHCSTGWG-----GVNCETP 657 G+ C+ ++ D +CSN G C G C C G G CE Sbjct: 122 YGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECD 181 Query: 658 LPVC-----QEQCSGHGTFLLDAGVCSCDPKWTGSDC----------STELCTME----C 698 C +E C GHG G C C W G C S CT C Sbjct: 182 DRECIDDETEEICGGHGKCY--CGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKIC 239 Query: 699 GSHGVCSRGICQCEEGWVGPT------------CEERSCHS--------HCTEHGQCKDG 738 + G C G C C + V PT C+ER C + C+ HGQC G Sbjct: 240 SNRGTCVCGECTCHD--VDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCG 297 Query: 739 KCECSPGWEG------DHCTIAHYLDAVRDGCPGL----CFGNGRCTLDQNGWHCVCQVG 788 +C+C GW G CT++ +++R C G C G G+C + C C Sbjct: 298 RCDCKAGWYGKKCEHPQSCTLSAE-ESIRK-CQGSSDLPCSGRGKCECGK----CTCYPP 351 Query: 789 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNC-----YISPLCQ 834 E C D D DG+ C C C + LCQ Sbjct: 352 GDRRVYGKTCE--CDDRRCEDLDGVV-CGGHGTCSCGRCVCERGWFGKLCQ 399 Score = 96.3 bits (238), Expect = 4e-19 Identities = 85/283 (30%), Positives = 106/283 (37%), Gaps = 78/283 (27%) Query: 583 WKGPECDVP----EEQCIDP-------TCFGHGTCIMGVCIC---VPG-YKGEICEEEDC 627 W G C + E +C P C G G C GVCIC PG + G +CE + Sbjct: 35 WPGAACRLSRAESERRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECHEW 94 Query: 628 L-----DPMCSNHGICVKGECHCSTGWGGVNCETPL----------PVCQEQ----CSGH 668 + C+ HG C G+C C GW G C+ P +C+ CS Sbjct: 95 VCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNA 154 Query: 669 GTFLLDAGVCSCDPKWTGS--------DCSTELCTME-----CGSHGVCSRGICQCEEGW 715 GT G C CD GS +C C + CG HG C G C C+ GW Sbjct: 155 GT--CHCGRCKCDNS-DGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGW 211 Query: 716 VGPTCE----------ERSCHSH----CTEHGQCKDGKCEC-----SPGW---EGDHCTI 753 G CE +R C S C+ G C G+C C + W GD C Sbjct: 212 HGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCEC 271 Query: 754 -AHYLDAVRDG-CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 AV D C G+G+C N C C+ GW G C Sbjct: 272 DERDCRAVYDRYSDDFCSGHGQC----NCGRCDCKAGWYGKKC 310 >gi|148833508 notch1 preproprotein [Homo sapiens] Length = 2555 Score = 143 bits (360), Expect = 3e-33 Identities = 100/362 (27%), Positives = 152/362 (41%), Gaps = 60/362 (16%) Query: 529 DDCSTN-CNGNGEC----ISGH--CHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV--- 578 D C +N CN C ++G C C G+ GP C++D G N G C+ Sbjct: 374 DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTL 433 Query: 579 ------CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICE--EED 626 C G+ GP C++ +C+ C TC+ + CIC+PGY+G CE ++ Sbjct: 434 GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDE 493 Query: 627 CLDPMCSNHGICV----KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG---VCS 679 C C ++G C+ + +C C TG+ G C+ + C +G LD C Sbjct: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCV 553 Query: 680 CDPKWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTCEER--SCHSH-CT 730 C +TG+ C ++ C + +G C G+ C C G+ G CE C S C Sbjct: 554 CTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR 613 Query: 731 EHGQCKDGK----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQ 786 G C+D C C G G +C I D C +G C +G+ C C+ Sbjct: 614 HGGTCQDRDNAYLCFCLKGTTGPNCEIN------LDDCASSPCDSGTCLDKIDGYECACE 667 Query: 787 VGWSGTGCNVVMEMLCGDNLDNDG---DGLTDCV--------DPDCCQQSN-CYISPLCQ 834 G++G+ CN+ ++ G+ N G DG+ DP C + N C +P Sbjct: 668 PGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVH 727 Query: 835 GS 836 G+ Sbjct: 728 GA 729 Score = 138 bits (347), Expect = 9e-32 Identities = 105/368 (28%), Positives = 152/368 (41%), Gaps = 64/368 (17%) Query: 535 CNGNGECISGH------CHCFPGFLGPDCARD--SC---PVLCGGNGEYEKG--HCVCRH 581 C GEC C C G+ G C D C P G + + G C C+ Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQA 897 Query: 582 GWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEE--DCLDPMCSNH 635 G+ G C+ + C C G+C G+ C C+PG++G CEE+ +C C N Sbjct: 898 GYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNG 957 Query: 636 GICV----KGECHCSTGWGGVNCETPLPVCQEQ-CSGHGTFL--LDAGVCSCDPKWTGSD 688 C C C G+ G++CE P C E C GT + +++ C C P +TGS Sbjct: 958 ANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSY 1017 Query: 689 CS---TELCTMECGSHGVCSRGI----CQCEEGWVGPTCEERSCHSHCTEHGQCKDG--- 738 C E + C G C G C C +G+ GP C+ H + CK+G Sbjct: 1018 CQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLV---HWCDSSPCKNGGKC 1074 Query: 739 -------KCECSPGWEGDHC---TIAHYLDAVRDGCP--GLCFGNGRCTLDQNGWHCVCQ 786 +CEC GW G +C +++ + A R G LC G C N HC CQ Sbjct: 1075 WQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQ 1134 Query: 787 VGWSGTGCNVVMEMLCGDNLDNDGDGLTD--------CV----DPDCCQQSNCYISPLCQ 834 G++G+ C +++ C + +G TD CV +C ++ + +S CQ Sbjct: 1135 AGYTGSYCEDLVDE-CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ 1193 Query: 835 GSPDPLDL 842 LDL Sbjct: 1194 NGGTCLDL 1201 Score = 136 bits (342), Expect = 3e-31 Identities = 116/396 (29%), Positives = 153/396 (38%), Gaps = 93/396 (23%) Query: 529 DDCSTN-CNGNGECI----SGHCHCFPGFLGPDCARD--SC---PVLC--GGNGEYEKG- 575 D C++N C G+C+ S CHC P F GP C +D C P LC GG E G Sbjct: 142 DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS 201 Query: 576 -HCVCRHGWKGPECDVPEEQCIDPTCFGHGTC-----IMGVCICVPGYKGEICEE--EDC 627 CVCR GP C+ P C C GTC + C C+PG+ G+ CEE +DC Sbjct: 202 YRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDC 261 Query: 628 LDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQ---EQCSGHGTFLLDAG--VC 678 C N G CV G C C W G C + CQ C GT G C Sbjct: 262 PGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNC 321 Query: 679 SCDPKWTGSDCSTE---------------------------------LCTM--------- 696 C WTG DCS LC + Sbjct: 322 VCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPC 381 Query: 697 ----ECGSHGVCSRGICQCEEGWVGPTC----EERSCHSHCTEH-GQCKDG----KCECS 743 C ++ V + IC C G+ GP C +E S ++ EH G+C + +C+C Sbjct: 382 NEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCL 441 Query: 744 PGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLC 802 G+ G C I V + C + C LDQ G + C+C G+ G C V + Sbjct: 442 QGYTGPRCEI-----DVNECVSNPCQNDATC-LDQIGEFQCICMPGYEGVHCEVNTDECA 495 Query: 803 GDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPD 838 ++G L D ++ C+ + LCQ D Sbjct: 496 SSPCLHNGRCL-DKINEFQCECPTGFTGHLCQYDVD 530 Score = 130 bits (328), Expect = 1e-29 Identities = 105/361 (29%), Positives = 143/361 (39%), Gaps = 51/361 (14%) Query: 523 TAIEIMDDCSTNCNGNGEC---ISGH-CHCFPGFLGPDC-----ARDSCPVLCGGN-GEY 572 T + +++C++N +G C ++G+ C C PG+ G +C +S P + GG + Sbjct: 712 TCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDM 771 Query: 573 EKGH-CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--E 625 G+ C CR G+ GP C +C C GTCI V C C+ Y G CE Sbjct: 772 TSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA 831 Query: 626 DCLDPMCSNHGICVKGE------CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG--- 676 C C N G C + E C C TGW G CE + C HG + Sbjct: 832 PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGY 891 Query: 677 VCSCDPKWTGSDCSTELCTME---CGSHGVCSRGI----CQCEEGWVGPTCEE--RSCHS 727 C C ++G +C T++ C + G C+ GI C C G+ G CEE C S Sbjct: 892 RCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECAS 951 Query: 728 H-CTEHGQCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWH 782 C C D C C G+ G HC + D CF G C N + Sbjct: 952 DPCRNGANCTDCVDSYTCTCPAGFSGIHCE-----NNTPDCTESSCFNGGTCVDGINSFT 1006 Query: 783 CVCQVGWSGTGC----NVVMEMLC-GDNLDNDGDGLTDCVDPDCCQQSNCY-ISPLCQGS 836 C+C G++G+ C N C DG G C P NC + C S Sbjct: 1007 CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSS 1066 Query: 837 P 837 P Sbjct: 1067 P 1067 Score = 130 bits (326), Expect = 2e-29 Identities = 98/362 (27%), Positives = 130/362 (35%), Gaps = 100/362 (27%) Query: 528 MDDCSTN-CNGNGECISG----HCHCFPGFLGP-------DCARDSCPVLCGGNGEYEKG 575 +DDC N C+ G C G C C PGF G +CA D C + Sbjct: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSY 967 Query: 576 HCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEE--DCLD 629 C C G+ G C+ C + +CF GTC+ G+ C+C PG+ G C+ + +C Sbjct: 968 TCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDS 1027 Query: 630 PMCSNHGICVKG------------------------------------------ECHCST 647 C + G C G C C + Sbjct: 1028 QPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPS 1087 Query: 648 GWGGVNCETPLPVCQ----------EQCSGHGTFLLDAGV---CSCDPKWTGSDCST--- 691 GW G+ C+ P C+ + HG +DAG C C +TGS C Sbjct: 1088 GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD 1147 Query: 692 ELCTMECGSHGVCSRGI----CQCEEGWVGPTCEER--SCHSH-CTEHGQCKD----GKC 740 E C + C+ + C+C G+ G C E C SH C G C D KC Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKC 1207 Query: 741 ECSPGWEGDHCTIAHYLDAVRDGCPGL--------CFGNGRCTLDQNGWHCVCQVGWSGT 792 C G +G HC I V D P + CF NG C G+ C C G+ G Sbjct: 1208 SCPRGTQGVHCEIN-----VDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE 1262 Query: 793 GC 794 C Sbjct: 1263 RC 1264 Score = 121 bits (303), Expect = 1e-26 Identities = 98/354 (27%), Positives = 136/354 (38%), Gaps = 75/354 (21%) Query: 526 EIMDDC-STNCNGNGECISG----HCHCFPGFLGPDCARD--SC---PVLCGGNGEYEKG 575 E +DDC NC G C+ G +C C P + G C D C P C G Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315 Query: 576 H----CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEEDC 627 H CVC +GW G +C + C CF TC V C C G G +C D Sbjct: 316 HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDA 375 Query: 628 LDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGS 687 C+ C+ G NC+T PV + +C+C +TG Sbjct: 376 ----------CISNPCN-----EGSNCDTN-PVNGK------------AICTCPSGYTGP 407 Query: 688 DCSTEL--CTM---ECGSHGVCSRGI----CQCEEGWVGPTCE-------ERSCHSHCTE 731 CS ++ C++ C G C + CQC +G+ GP CE C + T Sbjct: 408 ACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATC 467 Query: 732 HGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNGRCTLDQNGWHCVCQVGWS 790 Q + +C C PG+EG HC + D C C NGRC N + C C G++ Sbjct: 468 LDQIGEFQCICMPGYEGVHCEVN------TDECASSPCLHNGRCLDKINEFQCECPTGFT 521 Query: 791 GTGCNVVMEMLCGDNLDN-----DGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 839 G C ++ N DG CV + ++C + + + PDP Sbjct: 522 GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVD-IDECDPDP 574 Score = 116 bits (290), Expect = 3e-25 Identities = 96/353 (27%), Positives = 127/353 (35%), Gaps = 100/353 (28%) Query: 554 GPDCARDSCPVLCGGNGEYEKGH--CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM--- 608 GP C++ L GG E G CVC + GP C P C+ C GTC + Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNP-CLSTPCKNAGTCHVVDR 79 Query: 609 -GV----CICVPGYKGEICE---EEDCLDPMCSNHGIC-----VKGECHCSTGWGGVNCE 655 GV C C G+ G +C + CL C N G C + +C C GW G +C+ Sbjct: 80 RGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ 139 Query: 656 TPLPVCQEQCSGHGTFL-LDAG-VCSCDPKWTGSDCSTEL---------------CTMEC 698 P C+ G L +A +C C P + G C ++ C E Sbjct: 140 QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEV 199 Query: 699 GSHGV-----------------CSRGICQ----------------CEEGWVGPTCEER-- 723 GS+ CS CQ C G+ G CEE Sbjct: 200 GSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENID 259 Query: 724 SC-HSHCTEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGC---PGLCFGNGRCT 775 C ++C G C DG C C P W G +CT D C P C G C Sbjct: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCT------EDVDECQLMPNACQNGGTCH 313 Query: 776 LDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCY 828 G++CVC GW+G C+ +N+D DC C + C+ Sbjct: 314 NTHGGYNCVCVNGWTGEDCS--------ENID-------DCASAACFHGATCH 351 Score = 114 bits (284), Expect = 2e-24 Identities = 86/310 (27%), Positives = 118/310 (38%), Gaps = 49/310 (15%) Query: 528 MDDCSTNCNGNGECISG----HCHCFPGFLGPDCARD-----SCPVLCGGNGEYEKGH-- 576 +D+C + G C G C C PG+ G C + S P GG + Sbjct: 567 IDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 626 Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--EDCLDP 630 C C G GP C++ + C C GTC+ + C C PGY G +C ++C Sbjct: 627 CFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGN 685 Query: 631 MCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQEQCSGHGTFL--LDAGVCSCDPKW 684 C N G C G C C G+ C + + C HG L+ C CDP W Sbjct: 686 PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGW 745 Query: 685 TGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERS-----------CHSH-CTEH 732 +G++C ++ EC S+ + G C+ TC E C S+ C Sbjct: 746 SGTNC--DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQ 803 Query: 733 GQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRC--TLDQNGWHCVCQ 786 G C D KC C + G C + + P C G C + D + CVC Sbjct: 804 GTCIDDVAGYKCNCLLPYTGATCEV-----VLAPCAPSPCRNGGECRQSEDYESFSCVCP 858 Query: 787 VGWSGTGCNV 796 GW G C V Sbjct: 859 TGWQGQTCEV 868 Score = 64.3 bits (155), Expect = 2e-09 Identities = 73/302 (24%), Positives = 102/302 (33%), Gaps = 86/302 (28%) Query: 528 MDDCSTN-CNGNG--ECISG----HCHCFPGFLGPDCAR--DSC---PVLCGGN----GE 571 +++C +N C+ G C+ HC C G G C + C P GG Sbjct: 1268 VNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASN 1327 Query: 572 YEKGH-CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEICE--- 623 +G C C G++G C+ C C GTCI G C+C+ + G C+ Sbjct: 1328 TARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPA 1387 Query: 624 EEDCL-DPMCSNHGICVKG------ECHCSTGWGGVNC-------------ETPLPVCQE 663 CL C N G C C C + G+ C + P P+ +E Sbjct: 1388 SSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEE 1447 Query: 664 QC--------SGHGTFLLDAGVCSCDPKWTGSDCSTEL---------------------C 694 C +G+ L +C W G DCS C Sbjct: 1448 ACELPECQEDAGNKVCSLQCNNHACG--WDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHC 1505 Query: 695 TMECGSHGVCSRGI-CQCEEGWVGPT----CEERSCHSHCTEHGQCKDGKCECSPGWEGD 749 +C S G G CQ EG P C++ HC + C +CE W+G Sbjct: 1506 DSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQ--GCNSAECE----WDGL 1559 Query: 750 HC 751 C Sbjct: 1560 DC 1561 Score = 42.4 bits (98), Expect = 0.006 Identities = 54/210 (25%), Positives = 75/210 (35%), Gaps = 52/210 (24%) Query: 532 STNCNGNGECISGH----CHCFPGFLGPDCARDSCPVLCGGNGEYEKG-----------H 576 S C G CISG C C F GP+C + GGN Y +G Sbjct: 1354 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYR 1413 Query: 577 CVCRHGWKGPEC-------------DVP----EEQCIDPTC---FGHGTCIMGVCICVPG 616 C+C + G C D+P EE C P C G+ C + G Sbjct: 1414 CLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACG 1473 Query: 617 YKGEICEEEDCLDPM--CSNHGICVK----GEC--HCSTG---WGGVNCETPL----PVC 661 + G C + DP C+ C K G C C++ + G +C+ P+ Sbjct: 1474 WDGGDCSL-NFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLY 1532 Query: 662 QEQCSGH-GTFLLDAGVCSCDPKWTGSDCS 690 + C H D G S + +W G DC+ Sbjct: 1533 DQYCKDHFSDGHCDQGCNSAECEWDGLDCA 1562 Score = 33.9 bits (76), Expect = 2.3 Identities = 35/125 (28%), Positives = 51/125 (40%), Gaps = 16/125 (12%) Query: 729 CTEHGQC--KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL---CFGNGRC-TLDQNG-- 780 C++ G+ GKCE + G E C A +D P L C G C +D+ G Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVA 83 Query: 781 -WHCVCQVGWSGTGCNVVMEMLCGDNLDNDG---DGLT----DCVDPDCCQQSNCYISPL 832 + C C +G+SG C ++ C N +G D LT C P +C + Sbjct: 84 DYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP 143 Query: 833 CQGSP 837 C +P Sbjct: 144 CASNP 148 >gi|4557679 jagged 1 precursor [Homo sapiens] Length = 1218 Score = 138 bits (348), Expect = 7e-32 Identities = 99/363 (27%), Positives = 143/363 (39%), Gaps = 74/363 (20%) Query: 543 SGHCHCFPGFLGPDCARDSCPVLCGGNGEYEK--GHCVCRHGWKGPECD--VPEEQCIDP 598 +G+ C G++GP+C R C C K G C C++GW+G CD +P C+ Sbjct: 215 NGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHG 274 Query: 599 TC-----------FG-------------HGTCIMG-----------VCICVPGYKGEICE 623 C +G H C+ G C C GY G CE Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE 334 Query: 624 --EEDCLDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQ-EQCSGHGTF--LLD 674 E CL C N G C + EC CS GW G C T + C CS GT L++ Sbjct: 335 IAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVN 394 Query: 675 AGVCSCDPKWTG-------SDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCE--ERSC 725 C C P+WTG ++C + C + + C C GW+G C+ C Sbjct: 395 GFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454 Query: 726 HSHCTEHGQCKD----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGW 781 C C+D +C C PG+ GDHC + + C G C + N + Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCE-----RDIDECASNPCLNGGHCQNEINRF 509 Query: 782 HCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTD------CVDPDCCQQSNC-YISPLCQ 834 C+C G+SG C + ++ C N +G + C P+ + NC ++ C+ Sbjct: 510 QCLCPTGFSGNLCQLDID-YCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568 Query: 835 GSP 837 +P Sbjct: 569 TTP 571 Score = 125 bits (315), Expect = 4e-28 Identities = 115/425 (27%), Positives = 155/425 (36%), Gaps = 121/425 (28%) Query: 528 MDDCS-TNCNGNGEC---ISGH-CHCFPGFLGPDCARDS--CPVLCGGNGEYEKG----- 575 +DDCS NC+ G C ++G C C P + G C D+ C N + K Sbjct: 375 IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASY 434 Query: 576 HCVCRHGWKGPECDVPEEQCIDPTCFGHGTC---IMGV-CICVPGYKGEICEEE--DCLD 629 +C C GW G CD+ C+ C +C + G CIC PGY G+ CE + +C Sbjct: 435 YCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECAS 493 Query: 630 PMCSNHGICV----KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG---VCSCDP 682 C N G C + +C C TG+ G C+ + C+ +G + C C Sbjct: 494 NPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPE 553 Query: 683 KWTGSDCS-------------TELCTME-----------------CGSHGVCS-----RG 707 + G +CS + CT+ CG HG C + Sbjct: 554 DYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKF 613 Query: 708 ICQCEEGWVGPTCEER--SCHSH-CTEHGQCKDG----KCECSPGWEGDHCTI------- 753 C C +G+ G C E C S+ C G C DG KC CS GWEG +C Sbjct: 614 TCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQ 673 Query: 754 --AHYLDAVRD-----------GCPG-------------LCFGNGRCTLDQNGWHCVCQV 787 H RD G G C G C + + + C+C Sbjct: 674 NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPG 733 Query: 788 GWSGTGCNVVMEMLC-------GDNLDNDGDGLTDCV------DPDCCQQSN------CY 828 GW GT CN+ C G +G+ T CV P C Q +N CY Sbjct: 734 GWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFT-CVCKEGWEGPICAQNTNDCSPHPCY 792 Query: 829 ISPLC 833 S C Sbjct: 793 NSGTC 797 Score = 122 bits (305), Expect = 6e-27 Identities = 106/418 (25%), Positives = 147/418 (35%), Gaps = 117/418 (27%) Query: 532 STNCNGNGEC----ISGHCHCFPGFLGPDCAR---DSCPVLCGGNG-------------- 570 S C+ G C + C C PG+ GP C+ D P C G Sbjct: 342 SDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCP 401 Query: 571 -------------EYEKGHCV---------------CRHGWKGPECDVPEEQCIDPTCFG 602 E E CV C GW G CD+ C+ C Sbjct: 402 PQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG-QCQN 460 Query: 603 HGTC---IMGV-CICVPGYKGEICEE--EDCLDPMCSNHGICV----KGECHCSTGWGGV 652 +C + G CIC PGY G+ CE ++C C N G C + +C C TG+ G Sbjct: 461 DASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGN 520 Query: 653 NCETPLPVCQEQCSGHGTFLLDAG---VCSCDPKWTGSDCS-------------TELCTM 696 C+ + C+ +G + C C + G +CS + CT+ Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTV 580 Query: 697 E-----------------CGSHGVC-----SRGICQCEEGWVGPTCEE--RSCHSH-CTE 731 CG HG C + C C +G+ G C E C S+ C Sbjct: 581 AMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRN 640 Query: 732 HGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 787 G C DG KC CS GWEG +C + D C G C N ++C C+ Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCE-----TNINDCSQNPCHNGGTCRDLVNDFYCDCKN 695 Query: 788 GWSGTGCNVVMEMLCGDNLDNDGDGLTD------CVDPDCCQQSNCYISPLCQGSPDP 839 GW G C+ + C + N+G D C+ P + + C I+ P+P Sbjct: 696 GWKGKTCH-SRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNP 752 Score = 113 bits (283), Expect = 2e-24 Identities = 73/218 (33%), Positives = 92/218 (42%), Gaps = 35/218 (16%) Query: 601 FGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGIC-VKGECHCSTGWGGVNCET-- 656 FGH C G C+ G+ G C C HG C + G+C C GW G+ C+ Sbjct: 207 FGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCI 266 Query: 657 PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRG--------- 707 P P C HG + C C+ W G C +L CG+H C G Sbjct: 267 PHPGCV-----HG-ICNEPWQCLCETNWGGQLCDKDL--NYCGTHQPCLNGGTCSNTGPD 318 Query: 708 --ICQCEEGWVGPTCE--ERSCHSH-CTEHGQCKDG----KCECSPGWEGDHCTIAHYLD 758 C C EG+ GP CE E +C S C G CK+ +CECSPGW G C+ Sbjct: 319 KYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN---- 374 Query: 759 AVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 + D P C G C NG+ CVC W+G C + Sbjct: 375 -IDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411 Score = 99.8 bits (247), Expect = 3e-20 Identities = 91/324 (28%), Positives = 119/324 (36%), Gaps = 59/324 (18%) Query: 519 FVLTTAIEIMDDCSTN-CNGNGECISG----HCHCFPGFLGP-------DCARDSCPVLC 566 F T E ++DC +N C G CI G C C G+ G DC+++ C Sbjct: 621 FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680 Query: 567 GGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCI----MGVCICVPGYKGEIC 622 +C C++GWKG C + QC + TC GTC C+C G++G C Sbjct: 681 TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740 Query: 623 ---EEEDCLDPMCSNHGIC-VKGE---CHCSTGWGGVNCETPLPVCQE---QCSGHGTFL 672 CL C N G C V GE C C GW G P+C + CS H + Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEG-------PICAQNTNDCSPHPCYN 793 Query: 673 LDAGV-------CSCDPKWTGSDCS---TELCTMECGSHGVCSRGI----CQCEEGWVGP 718 V C C P + G DC E + C C I C C G G Sbjct: 794 SGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGA 853 Query: 719 TCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQ 778 C+E S T DG W+ D C L+ R C + G C L + Sbjct: 854 KCQEVSGRPCITMGSVIPDG-----AKWD-DDCNTCQCLNG-RIACSKVWCGPRPCLLHK 906 Query: 779 NGWHCVCQVGWSGTGCNVVMEMLC 802 C SG C +++ C Sbjct: 907 GHSECP-----SGQSCIPILDDQC 925 Score = 72.0 bits (175), Expect = 7e-12 Identities = 55/212 (25%), Positives = 76/212 (35%), Gaps = 30/212 (14%) Query: 645 CSTGWGGVNCETPLPVCQEQCSGHGTFLLDA-GVCSCDPKWTGSDCSTELCTMECG-SHG 702 C + G C C+ + G + D G +C W G +C+ +C C HG Sbjct: 187 CDDYYYGFGCNK---FCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHG 243 Query: 703 VCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQCKD-GKCECSPGWEGDHCTIAHYLDAV 760 C G C+C+ GW G C++ H C HG C + +C C W G C D Sbjct: 244 SCKLPGDCRCQYGWQGLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCD----KDLN 298 Query: 761 RDGCPGLCFGNGRCT-LDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGD-------- 811 G C G C+ + + C C G+SG C + D N G Sbjct: 299 YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358 Query: 812 ---------GLTDCVDPDCCQQSNCYISPLCQ 834 G T + D C +NC CQ Sbjct: 359 ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQ 390 >gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] Length = 1044 Score = 137 bits (344), Expect = 2e-31 Identities = 107/339 (31%), Positives = 127/339 (37%), Gaps = 79/339 (23%) Query: 531 CSTNCNGNGECISGH-CHCFPGFLGPDCA------------RDSCPVLCGGNGEYEKGHC 577 C+ C +G C+S CHC PG+ GPDC+ + C G G C Sbjct: 103 CTEECV-HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGAC 161 Query: 578 VCRHGWKGPECDVPEEQCIDPT----------CFGHGTC--IMGVCICVPGYKGEICEE- 624 VC G++G C EE C T C +C G C+C PGY G CEE Sbjct: 162 VCAAGFRGWRC---EELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEEL 218 Query: 625 -------EDC-LDPMCSNHGIC--VKGECHCSTGWGGVNCETPLPV------CQEQCSGH 668 C L C N G C + GEC C GW G C P P C + C H Sbjct: 219 CPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCH 278 Query: 669 GTFLLD--AGVCSCDPKWTGSDCSTEL--------CTMECGSH--GVCS--RGICQCEEG 714 D G C C + G C E C+ C H G CS G C+CE G Sbjct: 279 HGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPG 338 Query: 715 WVGPTCEERSCHS-----HCTEHGQCK----------DGKCECSPGWEGDHCTIAHYLDA 759 + GP C+ER C CT C G C C PGW G HC + + Sbjct: 339 YKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGY 398 Query: 760 VRDGC--PGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 DGC P C C G C C G+ G C V Sbjct: 399 YGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGEVCAV 435 Score = 135 bits (341), Expect = 4e-31 Identities = 115/429 (26%), Positives = 154/429 (35%), Gaps = 146/429 (34%) Query: 535 CNGNGEC--ISGHCHCFPGFLGPDCARD--------SCPVLC----GGNGEYEKGHCVCR 580 C +C I+G C C PGF+G CA +C +C GG G C C+ Sbjct: 409 CQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCK 468 Query: 581 HGWKGPECDVP----------EEQCIDPTCFGHGTC--IMGVCICVPGYKGEICE---EE 625 GW+G +C +P E C TC C I G C C PG+ G+ CE + Sbjct: 469 EGWQGLDCTLPCPSGTWGLNCNESC---TCANGAACSPIDGSCSCTPGWLGDTCELPCPD 525 Query: 626 DCLDPMCSNHGIC--------VKGECHCSTGWGGVNCETPLP------------------ 659 CS H C V G C C GW G+ C++ P Sbjct: 526 GTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 585 Query: 660 ------------------VCQEQCS----GHGTFLLD-------------AGVCSCDPKW 684 +CQ C GHG +G+C C P + Sbjct: 586 SCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGF 645 Query: 685 TGSDCS------------TELCTMECGSHGVCSR--GICQCEEGWVGPTCEER------- 723 +G+ C+ +LC+ C ++G CS G CQC GW+G C + Sbjct: 646 SGALCNQVCAGGYFGQDCAQLCS--CANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWG 703 Query: 724 -SCHSHCTEHG----QCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGN--GRCTL 776 +C C+ H +DG C C+PGW G CT CP FG GR Sbjct: 704 PACFHACSCHNGASCSAEDGACHCTPGWTGLFCT---------QRCPAAFFGKDCGRVCQ 754 Query: 777 DQNG-------WHCVCQVGWSGTGCNVVMEMLCGDNLDNDG-DGLTDCVDPDCCQQ--SN 826 QNG C C+ G++G C E C G L +C++ C Sbjct: 755 CQNGASCDHISGKCTCRTGFTGQHC----EQRCAPGTFGYGCQQLCECMNNSTCDHVTGT 810 Query: 827 CYISPLCQG 835 CY SP +G Sbjct: 811 CYCSPGFKG 819 Score = 125 bits (314), Expect = 6e-28 Identities = 92/323 (28%), Positives = 124/323 (38%), Gaps = 79/323 (24%) Query: 534 NCNGNGEC--------ISGHCHCF-------------PGFLGPDCARDSCPVLCGGNGEY 572 NC+ + +C ++GHC C PG GP+C+ SC GG+ Sbjct: 531 NCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCS-VSCSCENGGSCSP 589 Query: 573 EKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTC---------------IMGVCICVPGY 617 E G C C G++GP C ++ P +GHG I G+C C+PG+ Sbjct: 590 EDGSCECAPGFRGPLC----QRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGF 645 Query: 618 KGEICEE--------EDCLD-PMCSNHGIC--VKGECHCSTGWGGVNCETPL------PV 660 G +C + +DC C+N+G C + G C C GW G +C P Sbjct: 646 SGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPA 705 Query: 661 CQEQCSGHGTFLLDA--GVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGP 718 C CS H A G C C P WTG C+ G C R +CQC+ G Sbjct: 706 CFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD--CGR-VCQCQN---GA 759 Query: 719 TCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQ 778 +C+ S GKC C G+ G HC GC LC T D Sbjct: 760 SCDHIS-------------GKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDH 806 Query: 779 NGWHCVCQVGWSGTGCNVVMEML 801 C C G+ G C+ M+ Sbjct: 807 VTGTCYCSPGFKGIRCDQAALMM 829 Score = 124 bits (310), Expect = 2e-27 Identities = 95/318 (29%), Positives = 123/318 (38%), Gaps = 80/318 (25%) Query: 530 DCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECD 589 DC + G + ++G CHC G++G C ++ CP G G HC C +G Sbjct: 274 DCPCHHGGQCDHVTGQCHCTAGYMGDRC-QEECPF--GSFGFQCSQHCDCHNG------- 323 Query: 590 VPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLD----PMCSNHGIC------- 638 QC T G C C PGYKG C+E C + P C+ C Sbjct: 324 ---GQCSPTT---------GACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTIS 371 Query: 639 ---VKGECHCSTGWGGVNCETPLPV------CQEQC---SGHGTFLLDAGVCSCDPKWTG 686 V G C C GW G +C PV CQ C +G + G C+C P + G Sbjct: 372 CHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG-CTCAPGFMG 430 Query: 687 SDCSTELCT----------MECGSHGVCS--RGICQCEEGWVGPTCE--------ERSCH 726 C+ C + G CS G C C+EGW G C +C+ Sbjct: 431 EVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCN 490 Query: 727 SHCT--EHGQCK--DGKCECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNGRCT----LD 777 CT C DG C C+PGW GD C + DG GL C + C+ D Sbjct: 491 ESCTCANGAACSPIDGSCSCTPGWLGDTCEL-----PCPDGTFGLNCSEHCDCSHADGCD 545 Query: 778 QNGWHCVCQVGWSGTGCN 795 HC C GW+G C+ Sbjct: 546 PVTGHCCCLAGWTGIRCD 563 Score = 80.5 bits (197), Expect = 2e-14 Identities = 67/225 (29%), Positives = 84/225 (37%), Gaps = 54/225 (24%) Query: 613 CVPGYKGEICEEEDCLDPMCSN---HGICVKGE-CHCSTGWGGVNCETPL------PVCQ 662 C PGY E D P+C+ HG CV + CHC GWGG +C + P C Sbjct: 88 CCPGYY----ESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCS 143 Query: 663 EQCSGHGTFLLD--AGVCSCDPKWTGSDCSTELCTMECGSHG-------VCSRGI----- 708 +C L + G C C + G C ELC G+HG C G Sbjct: 144 NRCQCQNGALCNPITGACVCAAGFRGWRCE-ELCAP--GTHGKGCQLPCQCRHGASCDPR 200 Query: 709 ---CQCEEGWVGPTCEE----RSCHSHCTEHGQCKD--------GKCECSPGWEG----D 749 C C G+ G CEE S +HC C++ G+C C PGW G Sbjct: 201 AGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQ 260 Query: 750 HCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 C + CP C G+C D C C G+ G C Sbjct: 261 PCPPGTFGQNCSQDCP--CHHGGQC--DHVTGQCHCTAGYMGDRC 301 Score = 73.6 bits (179), Expect = 3e-12 Identities = 56/193 (29%), Positives = 74/193 (38%), Gaps = 49/193 (25%) Query: 530 DCST--NCNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKG 585 DC+ +C NG C I G C CFPG++G DC++ C G+ G Sbjct: 662 DCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------------------ACPPGFWG 703 Query: 586 PECDVPEEQCIDPTCFGHGTCIM--GVCICVPGYKGEICEE--------EDCLDP-MCSN 634 P C C +C +C G C C PG+ G C + +DC C N Sbjct: 704 PACF---HAC---SCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQN 757 Query: 635 HGIC--VKGECHCSTGWGGVNCETPLPV------CQEQCSGHGTFLLD--AGVCSCDPKW 684 C + G+C C TG+ G +CE CQ+ C D G C C P + Sbjct: 758 GASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGF 817 Query: 685 TGSDCSTELCTME 697 G C ME Sbjct: 818 KGIRCDQAALMME 830 Score = 62.0 bits (149), Expect = 8e-09 Identities = 43/137 (31%), Positives = 53/137 (38%), Gaps = 20/137 (14%) Query: 680 CDPKWTGSDCSTELCTMECGSHGVC-SRGICQCEEGWVGPTCEERSCHS-----HCTEHG 733 C + D LCT EC HG C S C CE GW GP C C S HC+ Sbjct: 89 CPGYYESGDFCIPLCTEEC-VHGRCVSPDTCHCEPGWGGPDCSS-GCDSDHWGPHCSNRC 146 Query: 734 QCKD--------GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVC 785 QC++ G C C+ G+ G C GC C + D C+C Sbjct: 147 QCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLC 206 Query: 786 QVGWSGTGCNVVMEMLC 802 G++G C E LC Sbjct: 207 APGYTGVYC----EELC 219 >gi|134244285 Notch homolog 3 [Homo sapiens] Length = 2321 Score = 135 bits (340), Expect = 6e-31 Identities = 95/309 (30%), Positives = 124/309 (40%), Gaps = 44/309 (14%) Query: 525 IEIMDDCSTNCNGNGECISG----HCHCFPGFLGPDCARDSCPVL---CGGNGEYEKG-- 575 +EI + S+ C G C+ G C C PG L P C S P C Y+ Sbjct: 656 VEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGG 715 Query: 576 -HCVCRHGWKGPEC--DVPEEQCIDPTCFGHGTCI---MGV-CICVPGYKGEICE-EEDC 627 CVC GW GP C + + C C GTC MG C C PG +G CE C Sbjct: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC 775 Query: 628 LDPMCSNHGICVKGE-----CHCSTGWGGVNCETPLPVC--QEQCSGHG--TFLLDAGVC 678 C + G C C C GW G C+ + C C HG T L + C Sbjct: 776 TPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC 835 Query: 679 SCDPKWTGSDCSTELCTME---CGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSHC 729 +C +TG C ++ + C + G C G+ C C G+ GP C + C S+ Sbjct: 836 TCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNP 895 Query: 730 TEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVC 785 G C D C C PG+ G HC + D P CF G C N + C+C Sbjct: 896 CGPGTCTDHVASFTCTCPPGYGGFHCE-----QDLPDCSPSSCFNGGTCVDGVNSFSCLC 950 Query: 786 QVGWSGTGC 794 + G++G C Sbjct: 951 RPGYTGAHC 959 Score = 134 bits (338), Expect = 9e-31 Identities = 115/419 (27%), Positives = 147/419 (35%), Gaps = 108/419 (25%) Query: 528 MDDCSTN-CNGNGECISG----HCHCFPGFLGPDCARDSCPVL---CGGN---GEYEKGH 576 ++DC N C G C G C C PGF GP CARD L CG Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFT 909 Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEE--DCLDP 630 C C G+ G C+ C +CF GTC+ GV C+C PGY G C+ E CL Sbjct: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969 Query: 631 MCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQEQ-CSGHGTFLLDAGVCSCDPKWT 685 C + G+C C C + G C+T + C Q C G + C C P W+ Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWS 1029 Query: 686 GSDCSTELCTME-------------CGSHGVC----SRGICQCEEGWVGPTCEER--SCH 726 G C C + G C S C C EG G CE+ C Sbjct: 1030 GRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL 1089 Query: 727 SHCTEHGQCKDG-----KCECSPGWEGDHC--------------------TIAHYLDAVR 761 + +HG G CEC PG+ GD+C +A YL + Sbjct: 1090 AQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCP 1149 Query: 762 DGCPGL--------------------CFGNGRCTLDQNGWHCVCQVGWSGTGCNV-VMEM 800 G G+ C NG C G+ C C G++G C + E Sbjct: 1150 PGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC 1209 Query: 801 LCG--------DNLDNDGDGLTDCV------DPDC------CQQSNCYISPLCQGSPDP 839 G D L + G G C+ P C C+ C C+ SP P Sbjct: 1210 RSGACHAAHTRDCLQDPGGGFR-CLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGP 1267 Score = 132 bits (333), Expect = 4e-30 Identities = 104/363 (28%), Positives = 141/363 (38%), Gaps = 67/363 (18%) Query: 531 CSTNCNGNGECISGHCH---------------CFPGFLGPDCARD-----SCPVLCGG-- 568 C T+ N EC+SG C C GF G C D S P + GG Sbjct: 428 CETDVN---ECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC 484 Query: 569 NGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE 624 C C G+ G C + ++C C C+ C C G++G +C+ Sbjct: 485 KDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR 544 Query: 625 --EDCLDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQEQCSGHG---TFLLDA 675 +DC C +HG CV G C C+ G+ G CE+ + C+ Q HG L+D Sbjct: 545 NVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK 603 Query: 676 GVCSCDPKWTGSDCSTEL--CTMECGSHGVCSRGI----CQCEEGWVGPTC--EERSC-H 726 +C C TG +C + C + GVC GI C C+ G+ GP C E C Sbjct: 604 YLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECAS 663 Query: 727 SHCTEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWH 782 S C E G C DG +C C PG C + A G+C+ G+ Sbjct: 664 SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYD------APGGFR 717 Query: 783 CVCQVGWSGTGCNVVM--------EMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 834 CVC+ GWSG C+ + G +DG G C P Q C + C Sbjct: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF-HCTCPPGVQGRQCELLSPCT 776 Query: 835 GSP 837 +P Sbjct: 777 PNP 779 Score = 126 bits (317), Expect = 3e-28 Identities = 103/350 (29%), Positives = 133/350 (38%), Gaps = 45/350 (12%) Query: 528 MDDCSTNCNGNGECISG----HCHCFPGFLGPDCAR--DSC---PVLCGGN--GEYEKGH 576 +DDCS + +G C+ G C C PG+ G C D C P GG +K Sbjct: 546 VDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605 Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEE--DCLDP 630 C C G G C+V + C C G C G+ C+C PG+ G +C E +C Sbjct: 606 CRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASS 664 Query: 631 MCSNHGICVKGE----CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG--VCSCDPKW 684 C G CV GE C C G C P C + HG G C C+P W Sbjct: 665 PCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGW 724 Query: 685 TGSDCSTELC-----TMECGSHGVCSRG----ICQCEEGWVGPTCEERS-CHSHCTEH-G 733 +G CS L + C + G CS C C G G CE S C + EH G Sbjct: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGG 784 Query: 734 QCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 788 +C+ C C GW+G C D P C +G CT + C C G Sbjct: 785 RCESAPGQLPVCSCPQGWQGPRC----QQDVDECAGPAPCGPHGICTNLAGSFSCTCHGG 840 Query: 789 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPD 838 ++G C+ + C N +G D V C + P C D Sbjct: 841 YTGPSCDQDIND-CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVD 889 Score = 120 bits (301), Expect = 2e-26 Identities = 107/394 (27%), Positives = 139/394 (35%), Gaps = 93/394 (23%) Query: 528 MDDC-STNCNGNGECIS----GHCHCFPGFLG-------PDCARDSCP--VLCGGNGEYE 573 +D+C S C G+C+ C C G G DCA + C V G Y+ Sbjct: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYD 642 Query: 574 KGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEIC--EEEDC 627 CVC+ G+ GP C+V +C C G+C+ G C+C PG +C C Sbjct: 643 ---CVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPC 699 Query: 628 LDPMCSNHGICVKG----ECHCSTGWGGVNCETPL--PVCQEQ-CSGHGTFLLDA----- 675 CS HGIC C C GW G C L C+ Q C GT D Sbjct: 700 AHEPCS-HGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHC 758 Query: 676 -----------------------------------GVCSCDPKWTGSDCSTEL--CT--M 696 VCSC W G C ++ C Sbjct: 759 TCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPA 818 Query: 697 ECGSHGVCSR----GICQCEEGWVGPTCEE--RSCHSH-CTEHGQCKDG----KCECSPG 745 CG HG+C+ C C G+ GP+C++ C + C G C+DG C C PG Sbjct: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPG 878 Query: 746 WEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDN 805 + G C D C G G CT + C C G+ G C + C + Sbjct: 879 FAGPRCA------RDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPD-CSPS 931 Query: 806 LDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPDP 839 +G D V+ C Y CQ DP Sbjct: 932 SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP 965 Score = 118 bits (296), Expect = 7e-26 Identities = 101/375 (26%), Positives = 147/375 (39%), Gaps = 70/375 (18%) Query: 528 MDDCSTN--CNGNGECI----SGHCHCFPGFLGPDCARDSCPVL---CGGNGEYEKG--- 575 +D+C C G C+ S C C G+ GP C + P C G + Sbjct: 159 VDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDL 218 Query: 576 --HCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--EDC 627 C C G++G C+V + C C GTC+ GV C C P + G+ C E ++C Sbjct: 219 TYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDEC 278 Query: 628 -LDP-MCSNHGICVK----GECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLD---AGVC 678 L P C N G C C C GW G +C + C HG D + C Sbjct: 279 QLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYC 338 Query: 679 SCDPKWTGSDCSTELCTME--------CGSHGVCSRGICQCEEGWVGPTC----EERSCH 726 +C TG C + + C ++ V R IC C G+ G C +E S Sbjct: 339 ACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIG 398 Query: 727 SHCTEH-GQCKDGK----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG- 780 ++ EH G+C + + C+C G+ G C V + G C C LD+ G Sbjct: 399 ANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE-----TDVNECLSGPCRNQATC-LDRIGQ 452 Query: 781 WHCVCQVGWSGTGCNVVMEM----------LCGDNLD-------NDGDGLTDCVDPDCCQ 823 + C+C G++GT C V ++ +C D ++ + G T +D D C Sbjct: 453 FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECA 512 Query: 824 QSNCYISPLCQGSPD 838 + C C PD Sbjct: 513 STPCRNGAKCVDQPD 527 Score = 115 bits (289), Expect = 5e-25 Identities = 88/352 (25%), Positives = 131/352 (37%), Gaps = 79/352 (22%) Query: 535 CNGNGECIS-----GHCHCFPGFLGPDCA-RDSCPV-LCGGNGEYEKG--------HCVC 579 C G C C C PG++G C D C C G G + C C Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108 Query: 580 RHGWKGPECDVPEEQCIDPTCFGHGTCIMG-----VCICVPGYKGEIC--EEEDC-LDPM 631 G++GP+C +P + C+ C C +G +C C PGY+G C + ++C + Sbjct: 109 PRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167 Query: 632 CSNHGICVKG----ECHCSTGWGGVNCETP-LPVCQEQCSGHGTFLLDAGV---CSCDPK 683 C + G C+ C C G+ G CE P +P C GT + C+C P Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227 Query: 684 WTGSDCSTELCTMECGSH-----GVCSRGI----CQCEEGWVGPTCEE---------RSC 725 + G +C E+ +C H G C G+ CQC W G C E +C Sbjct: 228 FEGQNC--EVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNAC 285 Query: 726 HSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVC 785 H+ T C C GW G+ C+ + D +CF C ++C C Sbjct: 286 HNGGTCFNTLGGHSCVCVNGWTGESCS-----QNIDDCATAVCFHGATCHDRVASFYCAC 340 Query: 786 QVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSP 837 +G +G C++ D C + C+ +C +P Sbjct: 341 PMGKTGLLCHL----------------------DDACVSNPCHEDAICDTNP 370 Score = 90.1 bits (222), Expect = 3e-17 Identities = 105/414 (25%), Positives = 141/414 (34%), Gaps = 125/414 (30%) Query: 528 MDDCSTN-CNGNGEC---ISGH-CHCFPGFLGPDCARD-----SCPVLCGGN--GEYEKG 575 +D C C G C + G+ C C PG+ G +C D S P GG+ + Sbjct: 1085 VDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARY 1144 Query: 576 HCVCRHGWKGPECDVPEEQC-------IDPTCFGHGTCIMGV----CICVPGYKGEICEE 624 C C G G C++ E+ C P C +GTC+ V C C PGY G CE Sbjct: 1145 LCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEA 1204 Query: 625 E--DCLDPMC--SNHGICVKG-----ECHCSTGWGGVNCETPLPVCQEQCSGHG------ 669 + +C C ++ C++ C C G+ G C+T L C+ Q HG Sbjct: 1205 DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPS 1264 Query: 670 -------TFLLDA-----------------------GV----------CSCDPKWTGSDC 689 TF GV C+C P +G C Sbjct: 1265 PGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSC 1324 Query: 690 ----------STELCTMECGSHGVCSRGI-------CQCEEGWVGPTCEERSCHSHCTEH 732 S C HG R C C +GW GP CE + +E Sbjct: 1325 RSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEE 1384 Query: 733 GQCKDGKC-----------ECSP---GWEGDHCTIAHYLDAVRDGCPGL----CFGNGRC 774 +C C EC+ GW+G C+++ D R C L F N RC Sbjct: 1385 PRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLS-VGDPWRQ-CEALQCWRLFNNSRC 1442 Query: 775 TLDQNGWHCV-----CQVGWSGTGCNVVMEMLCGDNLDNDGDGLTD--CVDPDC 821 + C+ C G CN V E C D+ DG D C +C Sbjct: 1443 DPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHF---ADGRCDQGCNTEEC 1493 Score = 40.4 bits (93), Expect = 0.024 Identities = 34/135 (25%), Positives = 44/135 (32%), Gaps = 42/135 (31%) Query: 714 GWVGPTCEERSCHSHCTEHGQC-----KDGKCECSPGWEGDHCTIAHYLDAVRDGC-PGL 767 G P C + S C G+C ++ C C PGW G+ C + D C G Sbjct: 37 GAAAPPCLDGS---PCANGGRCTQLPSREAACLCPPGWVGERCQL-------EDPCHSGP 86 Query: 768 CFGNGRC----TLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQ 823 C G G C + C C G+ G C++ PD C Sbjct: 87 CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSL----------------------PDPCL 124 Query: 824 QSNCYISPLCQGSPD 838 S C C PD Sbjct: 125 SSPCAHGARCSVGPD 139 Score = 36.2 bits (82), Expect = 0.45 Identities = 44/197 (22%), Positives = 56/197 (28%), Gaps = 87/197 (44%) Query: 546 CHCFPGFLGPDC----------ARDSC---PVLCGGNGEYEK----GHCVCRHGWKGPEC 588 C C PG GP C + SC P L GG+ C C GW GP C Sbjct: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC 1372 Query: 589 DVP--------------------------EEQCIDPTCFGHGTCIMGVCICVPGYKGEIC 622 + P + +C P C G G C G C Sbjct: 1373 EAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDG----GDCSLSVGDPWRQC 1428 Query: 623 EEEDC--------LDPMCSNHGICVKG-ECH----------------------------C 645 E C DP CS+ +CH C Sbjct: 1429 EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGC 1488 Query: 646 ST---GWGGVNCETPLP 659 +T GW G++C + +P Sbjct: 1489 NTEECGWDGLDCASEVP 1505 >gi|55770876 notch4 preproprotein [Homo sapiens] Length = 2003 Score = 135 bits (339), Expect = 7e-31 Identities = 95/339 (28%), Positives = 132/339 (38%), Gaps = 57/339 (16%) Query: 525 IEIMDDCSTNCNGNGEC---ISG-HCHCFPGFLGPDCARD-----SCPVLCGGNGEYEKG 575 +E + S C + +C ++G C C PGF G C D S P GG + + G Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571 Query: 576 --HCVCRHGWKGPECDVPEEQCIDPTCFGHGTCI----MGVCICVPGYKGEICEEEDCLD 629 HC C G++GP C ++C+ C +C+ C+C G+ G++CE C Sbjct: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631 Query: 630 PMCSNHGIC--VKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGS 687 +C IC K + +C G C P ++ C+ H C CD WTG Sbjct: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPP----EDNCTCHHGH-CQRSSCVCDVGWTGP 686 Query: 688 DCSTEL---CTMECGSHGVC----SRGICQCEEGWVGPTCEER--SCHS-HCTEHGQCKD 737 +C EL + C G C S C C G+ GPTC E +CHS C G C Sbjct: 687 ECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNP 746 Query: 738 GK----CECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNGRCTLDQNGWHCVCQVGWSGT 792 C C P G C + D C CF G C + C+C +G+ G Sbjct: 747 SPGGYYCTCPPSHTGPQCQTS------TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGP 800 Query: 793 GCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISP 831 C +G C D C ++ C SP Sbjct: 801 RC--------------EGKLRPSCADSPCRNRATCQDSP 825 Score = 135 bits (339), Expect = 7e-31 Identities = 95/339 (28%), Positives = 138/339 (40%), Gaps = 69/339 (20%) Query: 532 STNCNGNGECI---SGH-CHCFPGFLGPDCARD-----SCPVLCGGNGEYEKG--HCVCR 580 S C G C SG+ C C G+ GP C+ + S P L GG+ G +C C Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCP 756 Query: 581 HGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEE---DCLDPMCS 633 GP+C + C+ CF GTC+ C+C G++G CE + C D C Sbjct: 757 PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCR 816 Query: 634 NHGICVKG----ECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGV---CSCDPKWTG 686 N C C C TG+ G +C+T + +C ++ + L G C C WTG Sbjct: 817 NRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTG 876 Query: 687 SDCSTELCTME-------------CGSHGVCSRG----ICQCEEGWVGPTC-------EE 722 C+ L + + C + G+C C C G+ G C E Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCES 936 Query: 723 RSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWH 782 R C + T Q C+C+PG++G +C + LDA + C +G CT G+H Sbjct: 937 RPCQNGATCMAQPSGYLCQCAPGYDGQNC--SKELDACQS---QPCHNHGTCTPKPGGFH 991 Query: 783 CVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC 821 C C G+ G C +GD + +C+D C Sbjct: 992 CACPPGFVGLRC--------------EGD-VDECLDQPC 1015 Score = 127 bits (319), Expect = 2e-28 Identities = 107/358 (29%), Positives = 132/358 (36%), Gaps = 87/358 (24%) Query: 535 CNGNGECIS-----GHCHCFPGFLGPDCA-RDSC--PVLCGGNGEYE------------- 573 C G C+S G C C PGFLG C D C LC G + Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94 Query: 574 -----KGHCVCRHGWKGPECDVP-EEQCIDPTCFGHGTCIMGV-----CICVPGYKGEIC 622 C C G+ G C E+ C C G C + C C+PG+ GE C Sbjct: 95 SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC 154 Query: 623 EEED-CLDPMCSNHGICV----KGECHCSTGWGGVNCE--------TPLPVCQEQCSGHG 669 + D C C N G+C+ + +CHC G+ G CE P P C + S H Sbjct: 155 QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGP-CPKGTSCHN 213 Query: 670 TFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ-------------CEEGWV 716 T L + C C G C EL C G + G CQ C G++ Sbjct: 214 T--LGSFQCLCPVGQEGPRC--ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269 Query: 717 GPTCEER--SCHSH-CTEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCF 769 GP CE +C SH C G C+DG C C W G C + +D P C Sbjct: 270 GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC--SEDVDECETQGPPHCR 327 Query: 770 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827 G C +HCVC GW GT C +NLD DC+ C S C Sbjct: 328 NGGTCQNSAGSFHCVCVSGWGGTSCE--------ENLD-------DCIAATCAPGSTC 370 Score = 120 bits (302), Expect = 1e-26 Identities = 117/406 (28%), Positives = 149/406 (36%), Gaps = 113/406 (27%) Query: 529 DDC-STNCNGNGECISG----HCHCFPGFLGPDCARD--SC----PVLCGGNGEYEKG-- 575 D+C S C G C G C C + G DC+ D C P C G + Sbjct: 278 DNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337 Query: 576 --HCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEED-CL 628 HCVC GW G C+ + CI TC TCI V C+C PG G +C ED CL Sbjct: 338 SFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCL 397 Query: 629 ------DPMCSNHGICVKGECHCSTGWGGVNCETPLPVC------QEQCSGHGTFLLDAG 676 D CS + + C C G+ G C L C C G+ L G Sbjct: 398 SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPG 457 Query: 677 V--CSCDPKWTGSDCSTE------------------------LC------------TMEC 698 C C P +TGS C + LC T EC Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517 Query: 699 GS---------HGVCSRGICQCEEGWVGPTCEE--RSCHSH-CTEHGQCKDG----KCEC 742 S H + + C C G+ G CEE C S C GQC+D C+C Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKC 577 Query: 743 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVM--- 798 PG+EG C + + D CP G LD G + C+C G++G C V + Sbjct: 578 LPGFEGPRCQ-TEVDECLSDPCP-----VGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631 Query: 799 -----EMLCGDNLDNDG----DGLTDCVDPD--C------CQQSNC 827 + +C D D DG C P+ C CQ+S+C Sbjct: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677 Score = 120 bits (300), Expect = 2e-26 Identities = 86/318 (27%), Positives = 119/318 (37%), Gaps = 49/318 (15%) Query: 526 EIMDDCSTN-CNGNGECISGH----CHCFPGFLGPDCARD---------SCPVLCGGNGE 571 ++ D CS N C G C++ + CHC PGF G C RD CP + Sbjct: 155 QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNT 214 Query: 572 YEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTC--------IMGVCICVPGYKGEICE 623 C+C G +GP C++ C C GTC +C+C PG+ G CE Sbjct: 215 LGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE 274 Query: 624 --EEDCLDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQEQ----CSGHGTFLL 673 ++C+ C N G C G C C W G +C + C+ Q C GT Sbjct: 275 VNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQN 334 Query: 674 DAGV--CSCDPKWTGSDCSTEL---CTMECGSHGVCSRGI----CQCEEGWVGPTCE--- 721 AG C C W G+ C L C C + C C G G C Sbjct: 335 SAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLED 394 Query: 722 ---ERSCH--SHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL 776 + CH + C+ + C C PG+ G C + P C G C Sbjct: 395 MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454 Query: 777 DQNGWHCVCQVGWSGTGC 794 ++C+C G++G+ C Sbjct: 455 TPGSFNCLCPPGYTGSRC 472 Score = 106 bits (265), Expect = 3e-22 Identities = 92/316 (29%), Positives = 118/316 (37%), Gaps = 62/316 (19%) Query: 545 HCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHG 604 +C C G P CA C +G ++ CVC GW GPEC+ CI C G Sbjct: 648 NCLCPDG--SPGCAPPEDNCTCH-HGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGG 704 Query: 605 TCIMGV----CICVPGYKGEICEEEDCLDPMCSNH-GICVKGECHCSTGWGGVNCETPLP 659 TC C C GY G C EE M + H G C+ G C+ GG Sbjct: 705 TCYPQPSGYNCTCPTGYTGPTCSEE-----MTACHSGPCLNGG-SCNPSPGGY------- 751 Query: 660 VCQEQCSGHGTFLLDAGVCSCDPKWTGSDC--STELC-TMECGSHGVC----SRGICQCE 712 C+C P TG C ST+ C + C + G C C C Sbjct: 752 -----------------YCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCA 794 Query: 713 EGWVGPTCEER---SC-HSHCTEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGC 764 G+ GP CE + SC S C C+D +C C G+ G C L A + Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKP-- 852 Query: 765 PGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQ 824 C N C +HC+C GW+G CN+ + L D + C + C Sbjct: 853 ---CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909 Query: 825 SN----CYISPLCQGS 836 S C+ P QGS Sbjct: 910 SGPSYFCHCPPGFQGS 925 Score = 98.2 bits (243), Expect = 1e-19 Identities = 97/372 (26%), Positives = 141/372 (37%), Gaps = 76/372 (20%) Query: 499 MDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTN-CNGNGECI---SGH-CHCFPGFL 553 +D GP Y G F + + ++ C + C C+ SG+ C C PG+ Sbjct: 908 VDSGPSYFCHCPPG------FQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD 961 Query: 554 GPDCAR--DSC---PVLCGGNGEYEKG--HCVCRHGWKGPECDVPEEQCIDPTCFGHGTC 606 G +C++ D+C P G + G HC C G+ G C+ ++C+D C GT Sbjct: 962 GQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021 Query: 607 IMG------VCICVPGYKGEICEEE--DCLDPMCSNHGICVKGE-------CHCSTGWGG 651 C C+PG+ G+ CE E C C + G C CHC G+ G Sbjct: 1022 ACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEG 1081 Query: 652 VNCETPLPVCQEQCSGHGTFLLDAGV------CSCDPKWTGSDCSTELCTMECGS----- 700 C P C HG L + C+C + G DC T CG Sbjct: 1082 PTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCL 1141 Query: 701 -HGVCSRGI--------CQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCE--CS-PG--W 746 +G CS C C GP C++ C G+ DG C+ CS PG W Sbjct: 1142 YNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-C--EGRSGDGACDAGCSGPGGNW 1198 Query: 747 EGDHCTIAHYLDAVRDGCPG-----LCFGNGRCTLDQNGWHCV-----CQVGWSGTGCNV 796 +G C++ + GCP L F +G+C + C+ C+ + C Sbjct: 1199 DGGDCSLG--VPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCE---TPPACTP 1253 Query: 797 VMEMLCGDNLDN 808 + C D+ N Sbjct: 1254 AYDQYCHDHFHN 1265 Score = 77.4 bits (189), Expect = 2e-13 Identities = 81/317 (25%), Positives = 108/317 (34%), Gaps = 94/317 (29%) Query: 528 MDDCSTN-CNGNGECISG----HCHCFPGFLGPDCARDSCPVL---CGGNGEY------E 573 +D C + C+ +G C HC C PGF+G C D L C G Sbjct: 969 LDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLAN 1028 Query: 574 KGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTC-------IMGVCICVPGYKGEICEEE- 625 +C C G G C+V + C CF GTC + +C C G++G C Sbjct: 1029 AFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRA 1088 Query: 626 -DCLDPMCSNHGICVKG-------ECHCSTGWGGVNCETPL------------------- 658 C C + G+C+ C C +G+GG +C TP Sbjct: 1089 PSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSE 1148 Query: 659 -------------------PVCQEQ----CSGH-GTFLLDAGVCSCDPKWTGSDCSTELC 694 P CQ+ C G G DAG W G DCS + Sbjct: 1149 TTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVP 1208 Query: 695 T--MECGSHGVC----SRGIC--QCEEG---WVGPTCE---------ERSCHSHCTEHGQ 734 C SH C G C QC+ + G CE ++ CH H +G Sbjct: 1209 DPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHF-HNGH 1267 Query: 735 CKDGKCECSPGWEGDHC 751 C+ G GW+G C Sbjct: 1268 CEKGCNTAECGWDGGDC 1284 >gi|21704277 jagged 2 isoform a precursor [Homo sapiens] Length = 1238 Score = 132 bits (331), Expect = 6e-30 Identities = 104/338 (30%), Positives = 130/338 (38%), Gaps = 48/338 (14%) Query: 531 CSTNCNG-NGEC-ISGHCHCFPGFLGPDCARDSCPVL--CGGNGEYEKGHCVCRHGWKGP 586 C CN +G C + G C C G+ G C D C C E C C W G Sbjct: 245 CKQGCNLLHGGCTVPGECRCSYGWQGRFC--DECVPYPGCVHGSCVEPWQCNCETNWGGL 302 Query: 587 ECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICE--EEDCLDPMCSNHGIC 638 CD C C GTCI C C GY G CE E C C+N G C Sbjct: 303 LCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC 362 Query: 639 VK----GECHCSTGWGGVNCETPLPVC-QEQCSGHGTFL--LDAGVCSCDPKWTGSDCST 691 + ECHC +GW G C + C C+ GT + +D C C +W G+ C Sbjct: 363 HEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL 422 Query: 692 ELCTME---CGSHGVCSRGI----CQCEEGWVGPTC--EERSCHSHCTEHGQCKD----G 738 + E C + C I C C GW G C C C G CKD Sbjct: 423 DANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGY 482 Query: 739 KCECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNGRCTLDQNGWHCVCQVGWSGTGCNVV 797 +C C G+ G HC + RD C C G C +G+HC C G+SG C V Sbjct: 483 QCVCPRGFGGRHCELE------RDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVD 536 Query: 798 MEMLCGDNLDNDG------DGLTDCVDPDCCQQSNCYI 829 ++ LC + +G +G C PD NC + Sbjct: 537 VD-LCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV 573 Score = 121 bits (304), Expect = 8e-27 Identities = 103/361 (28%), Positives = 147/361 (40%), Gaps = 58/361 (16%) Query: 535 CNGNGECISGH-----CHCFPGFLGPDC--ARDSC---PVLCGGN-GEYEKG-HCVCRHG 582 C G CI+ C C G+ G +C A +C P GG+ E G C C G Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376 Query: 583 WKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEIC--EEEDCLDPMCSNHG 636 W GP C + ++C C GTC+ V CIC + G C + +C C N Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAF 436 Query: 637 IC---VKG-ECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKWTGSDCS 690 C + G C C GW G+NC + C+ QC GT L++ C C + G C Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCE 496 Query: 691 ---TELCTMECGSHGVC---SRGI-CQCEEGWVGPTCE---ERSCHSHCTEHGQC----K 736 E + C S G+C + G C C +G+ GP CE + S C +C Sbjct: 497 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 556 Query: 737 DGKCECSPGWEGDHCTIAHY-----LDAVRDGC-------------PGLCFGNGRCTLDQ 778 D C C + G +C++ V DGC G+C +GRC Sbjct: 557 DYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP 616 Query: 779 NG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSP 837 G + C+C G++GT C+ ++ G N G + D VD C + + LC +P Sbjct: 617 GGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCI-DEVDAFRCFCPSGWEGELCDTNP 675 Query: 838 D 838 + Sbjct: 676 N 676 Score = 118 bits (296), Expect = 7e-26 Identities = 93/323 (28%), Positives = 125/323 (38%), Gaps = 70/323 (21%) Query: 575 GHCVCRHGWKGPECDVPEEQCIDPTCFGHGTC-IMGVCICVPGYKGEICEEEDCLDPMCS 633 G+ C GW G EC E C HG C + G C C G++G C+E C+ Sbjct: 227 GNKACMDGWMGKECK--EAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDE--CVPYPGC 282 Query: 634 NHGICVKG-ECHCSTGWGGVNCETPLPVC--QEQCSGHGTFL---LDAGVCSCDPKWTGS 687 HG CV+ +C+C T WGG+ C+ L C C+ GT + D C+C ++G Sbjct: 283 VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGR 342 Query: 688 DC--STELCTME-CGSHGVC----SRGICQCEEGWVGPTCE---ERSCHSHCTEHGQCKD 737 +C + CT C + G C S C C GW GPTC + + C G C D Sbjct: 343 NCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVD 402 Query: 738 --------------------------GK----------------CECSPGWEGDHCTIAH 755 GK C+C PGW+G +C I Sbjct: 403 QVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI-- 460 Query: 756 YLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTD 815 V D C G C G C NG+ CVC G+ G C + + C + + G D Sbjct: 461 ---NVND-CRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDE-CASSPCHSGGLCED 515 Query: 816 CVDPDCCQQSNCYISPLCQGSPD 838 D C + PLC+ D Sbjct: 516 LADGFHCHCPQGFSGPLCEVDVD 538 Score = 112 bits (281), Expect = 4e-24 Identities = 111/375 (29%), Positives = 137/375 (36%), Gaps = 66/375 (17%) Query: 519 FVLTTAIEIMDDC-STNCNGNGECISG----HCHCFPGFLGPDC---ARDSCPVLCGGNG 570 F T E +DDC C G CI C C G+ G C D P C G Sbjct: 628 FTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG 687 Query: 571 E----YEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC 622 +C C GWKG C E QC TC GTC C C PG+KG C Sbjct: 688 RCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTC 747 Query: 623 ---EEEDCLDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDA 675 + CL C N G CV C C GW G C C +G +D Sbjct: 748 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD- 806 Query: 676 GV----CSCDPKWTGSDCS---TELCTMECGSHGVCSRGI----CQCEEGWVGPTCEE-- 722 GV C C P + G DC E + C C I C C G GP C+E Sbjct: 807 GVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 866 Query: 723 ---RSCHSHCT--EHG----------QCKDGKCECSPGWEG-DHCTIAHYLDAVRDGCPG 766 RSC S T HG +C DG+ +CS W G C +A +A+ CP Sbjct: 867 GFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCP- 925 Query: 767 LCFGNGRCTLDQNGWHCV---CQVGWSGTGCNVVMEMLC---GDNLDNDGDGLTDCVDPD 820 G+ L++ C+ C+ W G C +LDN+ LT + D Sbjct: 926 ----LGQRCLEKAPGQCLRPPCE-AWGECGAEEPPSTPCLPRSGHLDNNCARLTLHFNRD 980 Query: 821 CCQQSNCYISPLCQG 835 Q + +C G Sbjct: 981 HVPQGTT-VGAICSG 994 Score = 65.5 bits (158), Expect = 7e-10 Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 41/213 (19%) Query: 661 CQEQCSGHGTFLLDA-GVCSCDPKWTGSDCSTELCTMECGS-HGVCS-RGICQCEEGWVG 717 C+ + G + D G +C W G +C +C C HG C+ G C+C GW G Sbjct: 211 CRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQG 270 Query: 718 PTCEERSCHSHCTEHGQC-KDGKCECSPGWEG-------DHCTIAHYL-----------D 758 C+E + C HG C + +C C W G ++C H D Sbjct: 271 RFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPD 329 Query: 759 AVRDGCP-----------------GLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEML 801 R CP C G C +G+ C C GWSG C + ++ Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE- 388 Query: 802 CGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 834 C N G D VD C ++ CQ Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQWVGATCQ 421 >gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] Length = 3144 Score = 132 bits (331), Expect = 6e-30 Identities = 92/320 (28%), Positives = 130/320 (40%), Gaps = 48/320 (15%) Query: 525 IEIMDDCSTNCNGNGECI----SGHCHCFPGFLGPDCA---RDSCPVLCGGNGEY----E 573 I++ D +C G+C + C C PGF G C + C NG Sbjct: 889 IDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTN 948 Query: 574 KGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--EDC 627 + C C + GP C++ +C C C+ C+C PGY G CE ++C Sbjct: 949 RFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDEC 1008 Query: 628 LDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQEQCSGHG--TFLLDAGVCSCD 681 L C + G+C+ G C C +G+ G +CET C HG T L++ CSCD Sbjct: 1009 LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCD 1068 Query: 682 PKWTGSDCSTEL--CT-MECGSHGVCSRGI----CQCEEGWVGPTCEER--SCHSH---- 728 T + C ++ CT + C + G C + C C G+ G CE+ +C Sbjct: 1069 ADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNS 1128 Query: 729 --CTEHGQCKDGK-----CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGW 781 C G C DG C C PG+ G C I + + C C NG+ Sbjct: 1129 VICLNGGICVDGPGHTFDCRCLPGFSGQFCEIN-----INECSSSPCLHGADCEDHINGY 1183 Query: 782 HCVCQVGWSGTGCNVVMEML 801 C CQ GWSG C +E + Sbjct: 1184 VCKCQPGWSGHHCENELECI 1203 Score = 114 bits (284), Expect = 2e-24 Identities = 103/367 (28%), Positives = 145/367 (39%), Gaps = 73/367 (19%) Query: 528 MDDCSTN-CNGNGEC----ISGHCHCFPGFLGPDCARDS--CPVL-CGGNGE----YEKG 575 +DDC N C N C +S C C + G C ++S C + C N Y+ Sbjct: 734 IDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSY 793 Query: 576 HCVCRHGWKGPECDVPEEQCIDPTCFGHGTC----IMG--VCICVPGYKGEICEEE---- 625 C C GW G C +C C G C I G VC+C P Y G+ C + Sbjct: 794 RCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC 853 Query: 626 DCLDPMCSNHGICV-----KGECHCSTGWGGVNCETPLPVCQ-EQCSGHGTF--LLDAGV 677 D L C N+ C+ C C + G NCE + C C +G +++ Sbjct: 854 DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFR 913 Query: 678 CSCDPKWTGSDCSTEL--CTME-CGSHGVC----SRGICQCEEGWVGPTCE---ERSCHS 727 C C P ++GS C E+ C+ E C ++G C +R C CE + GP CE + S Sbjct: 914 CICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKIS 973 Query: 728 HCTEHGQC---KDG-KCECSPGWEGDHCTIAHYLDAVRDGC-PGLCFGNGRCTLDQNGWH 782 C + C DG C C+PG+ G +C I D C C +G C N + Sbjct: 974 PCLDEENCVYRTDGYNCLCAPGYTGINCEIN------LDECLSEPCLHDGVCIDGINHYT 1027 Query: 783 CVCQVGWSGTGC---------NVVMEMLCGDNLDN-----DGDG--------LTDCVDPD 820 C C+ G+ GT C N + C + ++ D DG + DC Sbjct: 1028 CDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIP 1087 Query: 821 CCQQSNC 827 C + C Sbjct: 1088 CMNEGFC 1094 Score = 104 bits (259), Expect = 1e-21 Identities = 86/330 (26%), Positives = 131/330 (39%), Gaps = 62/330 (18%) Query: 556 DCARDSCPVLCGGNGEYEKGHCV--CRHGWKGPECDVPEEQCIDPTCFGHGTCIMG---- 609 DC SC G + +G+ C G+KG +C++ ++C C TCI Sbjct: 646 DCKSASCKN--GTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNY 703 Query: 610 --------------VCICVPGYKGEICEE--EDCLDPMCSNHGIC----VKGECHCSTGW 649 C+C PGY G CE+ +DC+ C ++ C + +C C + W Sbjct: 704 FCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDW 763 Query: 650 GGVNCETPLPVCQ-EQCSGHGTF--LLDAGVCSCDPKWTGSDCSTEL--CTME-CGSHGV 703 G CE C+ C + T L + C C WTG +CS E+ C + C + G+ Sbjct: 764 EGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGL 823 Query: 704 CSRG------ICQCEEGWVGPTCEER-----SCHSHCTEHGQC-----KDGKCECSPGWE 747 C +C C + G C +R H+ C + C + C C +E Sbjct: 824 CHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFE 883 Query: 748 GDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLD 807 G +C I V+D C G C N + C+C+ G+SG+ C + + + Sbjct: 884 GKNCEI-----DVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCK 938 Query: 808 NDGDGLTDCVDPDCCQQSNC---YISPLCQ 834 N+G CVD NC Y P C+ Sbjct: 939 NNG----TCVDLTNRFFCNCEPEYHGPFCE 964 Score = 89.4 bits (220), Expect = 5e-17 Identities = 70/251 (27%), Positives = 97/251 (38%), Gaps = 60/251 (23%) Query: 528 MDDC-STNCNGNGECISG----HCHCFPGFLGPDCARD-----SCPVLCGGNGEYEKGH- 576 +D+C S C +G CI G C C GF G C + S P L G E + Sbjct: 1005 LDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYP 1064 Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--EDCLDP 630 C C +C + C C G C CIC GY G CE+ ++C +P Sbjct: 1065 CSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEP 1124 Query: 631 -----MCSNHGICVKG-----ECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSC 680 +C N GICV G +C C G+ G CE ++ CS Sbjct: 1125 ELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCE-----------------ININECSS 1167 Query: 681 DPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCE-ERSCHSHCTEHGQCKDGK 739 P G+DC + + +C+C+ GW G CE E C + H C + + Sbjct: 1168 SPCLHGADCEDHI-----------NGYVCKCQPGWSGHHCENELECIPNSCVHELCMENE 1216 Query: 740 ----CECSPGW 746 C C+PG+ Sbjct: 1217 PGSTCLCTPGF 1227 Score = 68.6 bits (166), Expect = 8e-11 Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 48/232 (20%) Query: 588 CDVPEEQCIDPTCFGHGTC--IMGVCI--CVPGYKGEICEEE--DCLDPMCSNHGICVK- 640 C++ E C +C T + G CVPG+KG CE + +C C N C+ Sbjct: 640 CEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699 Query: 641 -GECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTEL--CTME 697 G C C P V +D C C+P + G C ++ C + Sbjct: 700 PGNYFCQ-------CVPPFKV------------VDGFSCLCNPGYVGIRCEQDIDDCILN 740 Query: 698 CGSHGVCSRGI-----CQCEEGWVGPTCEERS-------CHSHCTEHGQCKDGKCECSPG 745 H + + C C W G CE+ S C ++ T K +CEC+ G Sbjct: 741 ACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSG 800 Query: 746 WEGDHCTIAHYLDAVRDGCPGLCFGNGRC--TLDQNGWHCVCQVGWSGTGCN 795 W G +C+ + + + C G C + + C+C ++G C+ Sbjct: 801 WTGQNCS-----EEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCH 847 Score = 64.3 bits (155), Expect = 2e-09 Identities = 52/207 (25%), Positives = 73/207 (35%), Gaps = 39/207 (18%) Query: 531 CSTNCNG--NGECISGHC---------HCFPGFLGPDCA---RDSCPVLCGGNGEYEKGH 576 C TN N + C+ G C C C D + C G +K Sbjct: 1039 CETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA 1098 Query: 577 ----CVCRHGWKGPECDVPEEQCIDPT-----CFGHGTCIMGV-----CICVPGYKGEIC 622 C+C G+ G C+ + C +P C G C+ G C C+PG+ G+ C Sbjct: 1099 HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFC 1158 Query: 623 EEE--DCLDPMCSNHGIC---VKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG 676 E +C C + C + G C C GW G +CE L C + G Sbjct: 1159 EININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPG 1218 Query: 677 -VCSCDPKW----TGSDCSTELCTMEC 698 C C P + G C E+ + C Sbjct: 1219 STCLCTPGFMTCSIGLLCGDEIRRITC 1245 Score = 60.5 bits (145), Expect = 2e-08 Identities = 65/264 (24%), Positives = 92/264 (34%), Gaps = 48/264 (18%) Query: 535 CNGNGECISG------HCHCFPGFLGPDCAR-DSCPVL-CGGNG---------EYEKGHC 577 C+G+G+C+S CHC P F G C D+C C NG + + C Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242 Query: 578 VCRHGWKGPECDVPEEQCIDPTCFGHGTCI-----MGVCICVPGYKGEICE--EEDCLDP 630 VC + G C QC CF HG C +C C + G CE + C+ Sbjct: 243 VCHPPFTGKNCSEIIGQCQPHVCF-HGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301 Query: 631 MCSNHGICVKGEC----HCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG---VCSCDPK 683 + GIC C G N ET + +GT + +C C P Sbjct: 302 LFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI 361 Query: 684 WTGSDC---STELCTMECGSHGVCSR----GICQCEEGWVGPTCEERSCHS-----HCTE 731 +T C T + ++ C + C C G+ CE+ H +C Sbjct: 362 FTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLN 421 Query: 732 HGQCKD----GKCECSPGWEGDHC 751 C + K C PG + C Sbjct: 422 EEWCFNIIGRFKYVCIPGCTKNPC 445 Score = 56.2 bits (134), Expect = 4e-07 Identities = 49/151 (32%), Positives = 66/151 (43%), Gaps = 27/151 (17%) Query: 525 IEIMDDCSTNCNGNGECI-SGH---CHCFPGFLGPDCAR--DSCP------VLC--GGNG 570 I+I D S C G C S H C C G+ G C + D+C V+C GG Sbjct: 1078 IKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGIC 1137 Query: 571 EYEKGH---CVCRHGWKGPECDVPEEQCIDPTCFGHGTC---IMG-VCICVPGYKGEICE 623 GH C C G+ G C++ +C C C I G VC C PG+ G CE Sbjct: 1138 VDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE 1197 Query: 624 EE-DCLDPMCSNHGICVKGE----CHCSTGW 649 E +C+ C H +C++ E C C+ G+ Sbjct: 1198 NELECIPNSCV-HELCMENEPGSTCLCTPGF 1227 Score = 55.8 bits (133), Expect = 6e-07 Identities = 42/141 (29%), Positives = 60/141 (42%), Gaps = 24/141 (17%) Query: 602 GHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKG------ECHCSTGWGGVNCE 655 G C +G+ + V K + C+E CS HG C+ CHC + G C+ Sbjct: 155 GPSPCPLGLRLNVT-VKQQFCQES-LSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ 212 Query: 656 TPLPVCQ-EQCSGHGTFLL-------DAGVCSCDPKWTGSDCSTEL--CTMECGSHGVCS 705 L C + C +G+ + A C C P +TG +CS + C HG CS Sbjct: 213 E-LDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271 Query: 706 R-----GICQCEEGWVGPTCE 721 IC+C+E + GP CE Sbjct: 272 NITSNSFICECDEQFSGPFCE 292 Score = 48.9 bits (115), Expect = 7e-05 Identities = 89/404 (22%), Positives = 134/404 (33%), Gaps = 114/404 (28%) Query: 528 MDDCSTN-CNGNGECISGH---------CHCFPGFLGPDCAR--DSC-PVLC-GGNGEYE 573 +D CS C NG CI+ C C P F G +C+ C P +C GN Sbjct: 214 LDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNI 273 Query: 574 KGH---CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG--------------------- 609 + C C + GP C+V + C+ + G C Sbjct: 274 TSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDV 333 Query: 610 ---------------------VCICVPGYKGEICE--EEDCLDPMCSNHGICVKGE---- 642 +CIC P + +C+ + C N+ C K E Sbjct: 334 SEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYP 393 Query: 643 CHCSTGWGGVNCETPLPVC---------QEQC---SGHGTFLLDAGVCSCDPKWTGSD-- 688 C C +G+ NCE + C +E C G ++ G C+ +P W + Sbjct: 394 CSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG-CTKNPCWFLKNVY 452 Query: 689 -CSTELCTMECGSHGVC-SRGICQCEEGW-VG-PTCEERSCH----------SHCTEHGQ 734 LC HG+C +G Q E W +G E C ++CTE Sbjct: 453 LIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTE--- 509 Query: 735 CKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG--WHCVCQVGWSGT 792 D P C H +G +C C +++ + +C + W+G Sbjct: 510 --DATYVNDPEDNNSSCWFPH------EGTKEICANGCSCLSEEDSQEYRYLCFLRWAG- 560 Query: 793 GCNVVMEMLCGDNLDNDGDGLTDCVDP---DCCQQSNCYISPLC 833 N+ +E D+ +N+ C D C S YI LC Sbjct: 561 --NMYLENTT-DDQENECQHEAVCKDEINRPRCSCSLSYIGRLC 601 Score = 47.4 bits (111), Expect = 2e-04 Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 11/101 (10%) Query: 580 RHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEICEEEDCLDPMCSNH 635 RHG C VP C C +GTCI C C Y G++C+ C + C N Sbjct: 2326 RHGKNIENCHVP--WCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNG 2383 Query: 636 GICVKGE-----CHCSTGWGGVNCETPLPVCQEQCSGHGTF 671 CV C C G G C + + Q + SG F Sbjct: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAF 2424 Score = 44.7 bits (104), Expect = 0.001 Identities = 31/132 (23%), Positives = 50/132 (37%), Gaps = 20/132 (15%) Query: 720 CEERSCHSHCTEHGQC------KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNG 772 C+E C+ HG+C K C C P + G +C D C C NG Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-------DACSFKPCKNNG 226 Query: 773 RC-----TLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827 C D+ + CVC ++G C+ ++ C ++ G+ + C+ Sbjct: 227 SCINKRENWDEQAYECVCHPPFTGKNCSEIIGQ-CQPHVCFHGNCSNITSNSFICECDEQ 285 Query: 828 YISPLCQGSPDP 839 + P C+ S P Sbjct: 286 FSGPFCEVSAKP 297 Score = 44.7 bits (104), Expect = 0.001 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 22/125 (17%) Query: 689 CSTELCTMECGSHGVCSRGI------CQCEEGWVGPTCEERSCHSH--CTEHGQCKDGK- 739 C L + C HG C C C+ + G C+E S C +G C + + Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233 Query: 740 --------CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSG 791 C C P + G +C+ + + P +CF + N + C C +SG Sbjct: 234 NWDEQAYECVCHPPFTGKNCS-----EIIGQCQPHVCFHGNCSNITSNSFICECDEQFSG 288 Query: 792 TGCNV 796 C V Sbjct: 289 PFCEV 293 Score = 42.4 bits (98), Expect = 0.006 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 16/75 (21%) Query: 597 DPTCFGHGTCIMG----------VCICVPGYKGEICEEE-DCLDPMCSNHGICVKGE--- 642 D T G+ TC G C C+P + G C + CL+ +C + +C+ + Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFS 2934 Query: 643 --CHCSTGWGGVNCE 655 C C+ GW G CE Sbjct: 2935 YSCLCTLGWVGRYCE 2949 Score = 41.6 bits (96), Expect = 0.011 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 17/106 (16%) Query: 692 ELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHS--HCTEHGQCKDGKCECSPGWEGD 749 EL E G+ G + G C G C +C + CT +G C C P W G+ Sbjct: 2857 ELQLTEFGAKGGSNVGDCD------GTACGYNTCRNGGECTVNGTTFS--CRCLPDWAGN 2908 Query: 750 HCTIAHYLDAVRDGCPGLCFGNGRCTLDQN-GWHCVCQVGWSGTGC 794 C + + + LC C DQ+ + C+C +GW G C Sbjct: 2909 TCN--QSVSCLNN----LCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948 Score = 37.4 bits (85), Expect = 0.20 Identities = 24/101 (23%), Positives = 34/101 (33%), Gaps = 11/101 (10%) Query: 700 SHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDA 759 S G C C + G TC E +C C+ GW+G CT Sbjct: 2605 SVGQCHASPCSLMKCGNGGTCIESGTSVYCN-----------CTTGWKGSFCTETVSTCD 2653 Query: 760 VRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEM 800 P C C +G+ C C +G +G C + + Sbjct: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSI 2694 Score = 36.6 bits (83), Expect = 0.35 Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 12/84 (14%) Query: 622 CEEEDCLDPMCSNHGICVKGE----CHCSTGWGGVNCETPLPVCQEQ------CSGHGTF 671 C C C N G C++ C+C+TGW G C + C + CS T Sbjct: 2609 CHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC 2668 Query: 672 L-LDAG-VCSCDPKWTGSDCSTEL 693 + L G C C TG C L Sbjct: 2669 ISLPHGYTCFCPLGTTGIYCEQAL 2692 Score = 35.4 bits (80), Expect = 0.78 Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 15/76 (19%) Query: 600 CFGHGTCIMG----VCICVPGYKGEICEEE-DCLDPM------CSNHGICVK----GECH 644 C GTCI C C G+KG C E DP CS C+ C Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678 Query: 645 CSTGWGGVNCETPLPV 660 C G G+ CE L + Sbjct: 2679 CPLGTTGIYCEQALSI 2694 Score = 35.4 bits (80), Expect = 0.78 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 11/71 (15%) Query: 664 QCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTME--CGSHGVCSRG-----ICQCEEGWV 716 +C+ +GT C C P W G+ C+ + + C +C C C GWV Sbjct: 2889 ECTVNGTTFS----CRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWV 2944 Query: 717 GPTCEERSCHS 727 G CE ++ S Sbjct: 2945 GRYCENKTSFS 2955 Score = 34.7 bits (78), Expect = 1.3 Identities = 30/96 (31%), Positives = 34/96 (35%), Gaps = 27/96 (28%) Query: 544 GHCHCFPGFLGPDCARDSCPVLCGGNGE--YEKG---HCVCRHGWKGPECDVPEEQCIDP 598 G CH P C ++ GNG E G +C C GWKG C C DP Sbjct: 2607 GQCHASP-----------CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTC-DP 2654 Query: 599 T------CFGHGTCIM----GVCICVPGYKGEICEE 624 C TCI C C G G CE+ Sbjct: 2655 EHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690 Score = 32.3 bits (72), Expect = 6.6 Identities = 26/97 (26%), Positives = 34/97 (35%), Gaps = 28/97 (28%) Query: 641 GECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGV---CSCDPKWTGSDC--STELCT 695 G+CH S C G+G +++G C+C W GS C + C Sbjct: 2607 GQCHASP-------------CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653 Query: 696 MECGSHGVCSRG----------ICQCEEGWVGPTCEE 722 E CSRG C C G G CE+ Sbjct: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690 >gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] Length = 1140 Score = 130 bits (326), Expect = 2e-29 Identities = 103/370 (27%), Positives = 132/370 (35%), Gaps = 86/370 (23%) Query: 531 CSTNCNGNGECISGH-CHCFPGFLGPDCAR------------DSCPVLCGGNGEYEKGHC 577 C+ C +G CI+ + C C PG+ G +C+ C G G C Sbjct: 109 CADKCV-HGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGAC 167 Query: 578 VCRHGWKGPECDVPEEQCIDPT----------CFGHGTC--IMGVCICVPGYKGEICE-- 623 C G++G C E++C T C TC + G C C PGY G CE Sbjct: 168 HCAAGFRGWRC---EDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDL 224 Query: 624 ----------EEDCLDPMCSNHGIC--VKGECHCSTGWGGVNCETPLPV------CQEQC 665 E+ C C N G+C V GEC C +GW G C P P C ++C Sbjct: 225 CPPGKHGPQCEQRC---PCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQEC 281 Query: 666 SGHGTFLLDA--GVCSCDPKWTGSDCSTE--------LC--TMECGSHGVCSR--GICQC 711 H DA G C C P +TG C E LC T +C + G C G C C Sbjct: 282 QCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLC 341 Query: 712 EEGWVGPTCEER---------------SCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHY 756 E G+ G CE R CH T G+C C PGW G +C Sbjct: 342 EAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCS 401 Query: 757 LDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV-----VMEMLCGDNLDNDGD 811 + C +C D C C G+ G C+ + C D Sbjct: 402 PGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKND 461 Query: 812 GLTDCVDPDC 821 + VD C Sbjct: 462 AVCSPVDGSC 471 Score = 130 bits (326), Expect = 2e-29 Identities = 99/319 (31%), Positives = 128/319 (40%), Gaps = 78/319 (24%) Query: 530 DCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECD 589 +C + G + +G CHC PG+ G C +D CPV G G C C +G K Sbjct: 280 ECQCHNGGTCDAATGQCHCSPGYTGERC-QDECPV--GTYGVLCAETCQCVNGGK----- 331 Query: 590 VPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPM----CSNHGIC------- 638 C+ + G C+C G+ GE CE C + + C C Sbjct: 332 ----------CYH----VSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377 Query: 639 ---VKGECHCSTGWGGVNC-ETPLP-----VCQEQCSGHGTFLLDA--GVCSCDPKWTGS 687 + GEC C GW G+ C ET P CQ+ CS D+ G C+C P + G Sbjct: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGI 437 Query: 688 DCSTEL--------CTMECG--SHGVCS--RGICQCEEGWVGPTCEER--------SCH- 726 DCST C+ CG + VCS G C C+ GW G C R C+ Sbjct: 438 DCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNL 497 Query: 727 -SHCTEHGQCK--DGKCECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNGRCT----LDQ 778 C G C DG C C+PGW G+ C + +DG GL C C+ Sbjct: 498 TCQCLNGGACNTLDGTCTCAPGWRGEKCEL-----PCQDGTYGLNCAERCDCSHADGCHP 552 Query: 779 NGWHCVCQVGWSGTGCNVV 797 HC C GWSG C+ V Sbjct: 553 TTGHCRCLPGWSGVHCDSV 571 Score = 125 bits (315), Expect = 4e-28 Identities = 108/422 (25%), Positives = 150/422 (35%), Gaps = 128/422 (30%) Query: 534 NCNGNGEC--ISGHCHCFPGFLGPDCARD--------SCPVLCGGNGEYE----KGHCVC 579 +C +C ++G C C PGF G DC+ +C CG + G C C Sbjct: 414 SCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTC 473 Query: 580 RHGWKGPECDVPEEQCIDPT----------CFGHGTC--IMGVCICVPGYKGEICEEEDC 627 + GW G +C + +C T C G C + G C C PG++GE CE C Sbjct: 474 KAGWHGVDCSI---RCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELP-C 529 Query: 628 LDPM----------CSNHGIC--VKGECHCSTGWGGVNCET-----------PLP----- 659 D CS+ C G C C GW GV+C++ LP Sbjct: 530 QDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKN 589 Query: 660 --------------------VCQEQCS----GH-------------GTFLLDAGVCSCDP 682 CQ CS GH G G+C C P Sbjct: 590 GASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLP 649 Query: 683 KWTGSDCSTELCTM-----------ECGSHGVCSR--GICQCEEGWVGPTCEE------- 722 +TG+ C+ E+C C ++G C+ CQC GW+G C + Sbjct: 650 GFTGALCN-EVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHW 708 Query: 723 -----RSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLD 777 +C+ H DG+C+C+PGW G +CT L C +C D Sbjct: 709 GPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCD 768 Query: 778 QNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDG-DGLTDCVDPDCCQQ--SNCYISPLCQ 834 C C+ G+ G C E C G + DC++ C CY SP + Sbjct: 769 HISGQCTCRTGFMGRHC----EQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWK 824 Query: 835 GS 836 G+ Sbjct: 825 GA 826 Score = 117 bits (293), Expect = 2e-25 Identities = 87/308 (28%), Positives = 119/308 (38%), Gaps = 69/308 (22%) Query: 543 SGHCHCFPGFLGPDC----------ARDSCPVLC--GGNGEYEKGHCVCRHGWKGPECDV 590 +GHC C PG+ G C S P C G + + G C C G++G C Sbjct: 554 TGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTC-- 611 Query: 591 PEEQCIDPTCFGH-------------GTC--IMGVCICVPGYKGEICEE--------EDC 627 ++ P +GH G C I G+C C+PG+ G +C E ++C Sbjct: 612 --QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC 669 Query: 628 LDPM-CSNHGIC--VKGECHCSTGWGGVNCETPLPV------CQEQCSGHGTFLLDA--G 676 C+N+G C + C C GW G +C P P C C+ H A G Sbjct: 670 AGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDG 729 Query: 677 VCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCK 736 C C P WTG C T+ C + G +G ICQC+ G C+ S Sbjct: 730 ECKCTPGWTGLYC-TQRCPL--GFYGKDCALICQCQNG---ADCDHIS------------ 771 Query: 737 DGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 G+C C G+ G HC GC +C T D C C GW G C+ Sbjct: 772 -GQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830 Query: 797 VMEMLCGD 804 ++ G+ Sbjct: 831 AGVIIVGN 838 Score = 68.9 bits (167), Expect = 6e-11 Identities = 45/159 (28%), Positives = 62/159 (38%), Gaps = 42/159 (26%) Query: 535 CNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGN-------------GEYEKGHCVC 579 C NG C I C C+PG++G DC++ P G N Y+ G C C Sbjct: 675 CTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYD-GECKC 733 Query: 580 RHGWKGPECD-------VPEEQCIDPTCFGHGTC--IMGVCICVPGYKGEICEEE----- 625 GW G C ++ + C C I G C C G+ G CE++ Sbjct: 734 TPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGT 793 Query: 626 ---------DCLDPMCSNHGICVKGECHCSTGWGGVNCE 655 DCL+ +H + G C+CS GW G C+ Sbjct: 794 YGYGCRQICDCLNNSTCDH---ITGTCYCSPGWKGARCD 829 Score = 45.4 bits (106), Expect = 7e-04 Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 16/76 (21%) Query: 530 DCST--NCNGNGEC--ISGHCHCFPGFLGPDC------------ARDSCPVLCGGNGEYE 573 DC+ C +C ISG C C GF+G C R C L ++ Sbjct: 754 DCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHI 813 Query: 574 KGHCVCRHGWKGPECD 589 G C C GWKG CD Sbjct: 814 TGTCYCSPGWKGARCD 829 >gi|41327708 crumbs homolog 1 precursor [Homo sapiens] Length = 1406 Score = 129 bits (323), Expect = 5e-29 Identities = 100/353 (28%), Positives = 150/353 (42%), Gaps = 79/353 (22%) Query: 529 DDCSTN-CNGNGECISG----HCHCFPGFLG-------PDCARDSCPVLCGGNGEYEKGH 576 D+C+++ C C G C C PG+ G +CA D C E + Sbjct: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209 Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTC--IMGV--CICVPGYKGEICE--EEDCLDP 630 C+C H + G C++ ++C C TC +G C C PG+ G+ CE ++C Sbjct: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ 269 Query: 631 MCSNHGICVKGE----CHCS-TGWGGVNCETPLPVC-QEQCSGHGTF--LLDAGVCSCDP 682 C + G+CV GE C+C+ +G+ G +CET +P+C + C + T +D C C P Sbjct: 270 PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWP 329 Query: 683 KWTGSDCSTEL--CTME-CGSHGVC------------------------SRGICQCEEGW 715 +TG+ C +L C C S+G C S +C C+ G+ Sbjct: 330 GYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF 389 Query: 716 VGPTCEE--RSCHSHCTEHGQCKDGKCECSPGWEGDHC---TIAHYLDAVRD------GC 764 G CEE C S+ ++G G CE PG HC ++ RD GC Sbjct: 390 TGIHCEEDVNECSSNPCQNG----GTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGC 445 Query: 765 PGL-CFGNGRCTLD----QNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDG 812 C NG C Q+G+ C+C G++G+ C + L +GDG Sbjct: 446 THQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI------ATTLSFEGDG 492 Score = 122 bits (306), Expect = 5e-27 Identities = 94/348 (27%), Positives = 136/348 (39%), Gaps = 75/348 (21%) Query: 529 DDCSTN-CNGNGECI------SGHCHCFPGFLGP-------DCARDSCPV--LCGGNGEY 572 D C +N C G+ C+ S C C PG+ G C ++SC +C + Y Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIY 131 Query: 573 EKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEIC--EEED 626 C+C G+ G C++ ++C C C G+ C CVPGY+G C E ++ Sbjct: 132 PV--CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189 Query: 627 CLDPMCSNHGICV----KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDA---GVCS 679 C C N C+ + C C + GVNCE + C Q +G DA C Sbjct: 190 CASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249 Query: 680 CDPKWTGSDCSTELCTMECGSH-----GVC----SRGICQCE-EGWVG-------PTCEE 722 C P + G C EL T EC S G+C +R C C G+ G P C Sbjct: 250 CAPGFLGDHC--ELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307 Query: 723 RSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT------- 775 + CH++ T + C C PG+ G C I + + C NG C Sbjct: 308 KPCHNNATCEDSVDNYTCHCWPGYTGAQCEI-----DLNECNSNPCQSNGECVELSSEKQ 362 Query: 776 -------------LDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDG 810 + +G+ C+CQ G++G C + + N G Sbjct: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGG 410 Score = 100 bits (250), Expect = 2e-20 Identities = 79/279 (28%), Positives = 107/279 (38%), Gaps = 38/279 (13%) Query: 587 ECDVPEEQCIDPTCFGHGTCI------MGVCICVPGYKGEICEEE--DCLDPMCSNHGIC 638 +CD ++ C C G TC+ +C C PGY G ICE C C + GIC Sbjct: 66 DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGIC 125 Query: 639 ----VKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFL---LDAGVCSCDPKWTGSDCST 691 + C C G+ G CE C +G +D C C P + G C Sbjct: 126 HQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL 185 Query: 692 EL--CTME-CGSHGVC----SRGICQCEEGWVGPTCEER--SCHSH-CTEHGQCKDGK-- 739 E+ C + C + C R C C + G CE C S C C+D Sbjct: 186 EVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGA 245 Query: 740 --CECSPGWEGDHCTIAHYLDAVRDGCPGL-CFGNGRCTLDQNGWHCVCQ-VGWSGTGCN 795 C+C+PG+ GDHC + D C C G C +N + C C G++GT C Sbjct: 246 YFCDCAPGFLGDHCELN------TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE 299 Query: 796 VVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 834 +M LC ++ D VD C Y C+ Sbjct: 300 TLMP-LCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCE 337 Score = 78.6 bits (192), Expect = 8e-14 Identities = 65/243 (26%), Positives = 92/243 (37%), Gaps = 58/243 (23%) Query: 560 DSCPVLCGGNGE--YEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGY 617 +S P L GGN E Y HC C GW G C++ ++C C HG Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI-HG------------- 1189 Query: 618 KGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQE-QCSGHGTFLLDAG 676 +C D + + H C C G+ GVNCE + CQ QC+ T + Sbjct: 1190 --------NCSDRVAAYH-------CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN 1234 Query: 677 --VCSCDPKWTGSDC-STELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHG 733 C C +TG C + L + CG+ + C G +CTE Sbjct: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNE----KTNLTCYNG------------GNCTEFQ 1278 Query: 734 QCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 793 + KC C PG+ G+ C + + C G C N + C+C V ++G Sbjct: 1279 T--ELKCMCRPGFTGEWCE-----KDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGER 1331 Query: 794 CNV 796 C V Sbjct: 1332 CEV 1334 Score = 72.0 bits (175), Expect = 7e-12 Identities = 60/242 (24%), Positives = 90/242 (37%), Gaps = 42/242 (17%) Query: 494 GFIEYMDQGPWYLAFYND-----GKKMEQVFVLTTAIEIMDDC-------STNCNGNGEC 541 G + ++ G YL+++ + K E+ F+ + ++ C S C G C Sbjct: 1095 GCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNC 1154 Query: 542 ----ISGHCHCFPGFLGPDCAR--DSC---PVLCGGNGEYEKG-HCVCRHGWKGPECDVP 591 S HC C G+ G C D C P + G + HC C G+ G C+V Sbjct: 1155 EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVD 1214 Query: 592 EEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEEDCLDPMCSNHG---ICVKG--- 641 + C C TCI C+C + G+ C + +C N C G Sbjct: 1215 IDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC 1274 Query: 642 -------ECHCSTGWGGVNCETPLPVC-QEQCSGHGTF--LLDAGVCSCDPKWTGSDCST 691 +C C G+ G CE + C + C G LL+ C CD + G C Sbjct: 1275 TEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334 Query: 692 EL 693 +L Sbjct: 1335 DL 1336 Score = 61.2 bits (147), Expect = 1e-08 Identities = 54/211 (25%), Positives = 76/211 (36%), Gaps = 40/211 (18%) Query: 604 GTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQE 663 G + VC P G CE D S H C C GW G +CE + C Sbjct: 1136 GCLQLNVCNSNPCLHGGNCE-----DIYSSYH-------CSCPLGWSGKHCELNIDECFS 1183 Query: 664 QCSGHGTFL--LDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCE 721 HG + A C+C+P +TG +C ++ C SH QC G Sbjct: 1184 NPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDN--CQSH--------QCANG------- 1226 Query: 722 ERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAV--RDGCPGLCFGNGRCTLDQN 779 +C SH + C C + G C + V + C+ G CT Q Sbjct: 1227 -ATCISHTNGYS------CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279 Query: 780 GWHCVCQVGWSGTGCNVVMEMLCGDNLDNDG 810 C+C+ G++G C ++ D N G Sbjct: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGG 1310 Score = 49.3 bits (116), Expect = 5e-05 Identities = 40/142 (28%), Positives = 53/142 (37%), Gaps = 46/142 (32%) Query: 528 MDDCSTN-CNGNGECI-----------------------SGH-CHCFPGFLGPDCARD-- 560 +++C++N C NGEC+ SG+ C C PGF G C D Sbjct: 340 LNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVN 399 Query: 561 ---SCPVLCGGNGEYEKGHCVC--------RHGWKGPECDVPEEQCIDPTCFGHGTCIMG 609 S P GG E G+ C R + G +C C C +GTCI Sbjct: 400 ECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPH 459 Query: 610 V--------CICVPGYKGEICE 623 C+C GY G +CE Sbjct: 460 FQDGQHGFSCLCPSGYTGSLCE 481 Score = 37.7 bits (86), Expect = 0.16 Identities = 36/140 (25%), Positives = 48/140 (34%), Gaps = 26/140 (18%) Query: 720 CEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGC-PGLCFGNGRC--TL 776 C SC ++ T KD C CS + D ++D C C G+ C T Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTAN----NLDKDCDNMKDPCFSNPCQGSATCVNTP 89 Query: 777 DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGD------------------GLTDCVD 818 + + C C G+SGT C + CG N G G +D Sbjct: 90 GERSFLCKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEID 148 Query: 819 PDCCQQSNCYISPLCQGSPD 838 D C S C +CQ D Sbjct: 149 HDECASSPCQNGAVCQDGID 168 Score = 34.7 bits (78), Expect = 1.3 Identities = 22/82 (26%), Positives = 29/82 (35%), Gaps = 16/82 (19%) Query: 768 CFGNGRCTLDQNGWHCVCQVGWSGTGC---------NVVMEMLCGDNL-------DNDGD 811 C G C + +HC C +GWSG C N + C D + + Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYT 1207 Query: 812 GLTDCVDPDCCQQSNCYISPLC 833 G+ VD D CQ C C Sbjct: 1208 GVNCEVDIDNCQSHQCANGATC 1229 >gi|122937343 platelet endothelial aggregation receptor 1 [Homo sapiens] Length = 1037 Score = 128 bits (321), Expect = 9e-29 Identities = 100/337 (29%), Positives = 119/337 (35%), Gaps = 75/337 (22%) Query: 531 CSTNC----NGNGECISGHCHCFPGFLGPDCAR----DSCPVLCGGNGEYEK-------- 574 C +C G + SG C C PG+ GP CA D+ V C E Sbjct: 404 CQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPID 463 Query: 575 GHCVCRHGWKGPECDVPEEQCIDPT----------CFGHGTCI--MGVCICVPGYKGEIC 622 G CVC+ GW+ C VP C T C C G C C PG+ G C Sbjct: 464 GECVCKEGWQRGNCSVP---CPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC 520 Query: 623 E--------EEDCLDPM-CSNHGIC--VKGECHCSTGWGGVNCETPLPV------CQEQC 665 + E C C + C V G C C GW G C P C C Sbjct: 521 QLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTC 580 Query: 666 S--GHGTFLLDAGVCSCDPKWTGSDC---------STELCTMECGSHGVC--SRGICQCE 712 + GT L + G C C P + G C +C +H C S G C C Sbjct: 581 TCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCL 640 Query: 713 EGWVGPTCEE--------RSCHSHCTEH--GQC--KDGKCECSPGWEGDHCTIAHYLDAV 760 GW GP C + +C C H G C +DG C C GW G HC L Sbjct: 641 AGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTF 700 Query: 761 RDGCPGLC-FGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 C C G G + G CVC G SG C + Sbjct: 701 GANCSQPCQCGPGEKCHPETG-ACVCPPGHSGAPCRI 736 Score = 125 bits (315), Expect = 4e-28 Identities = 101/362 (27%), Positives = 135/362 (37%), Gaps = 84/362 (23%) Query: 535 CNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPE 592 C+ G C +G C C PG+ G C R+ CPV G G +C Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRC-REECPV-----------------GRFGQDCAETC 319 Query: 593 EQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPM----CSNHGIC---------- 638 + D CF G C+C G+ G+ C + C D C C Sbjct: 320 DCAPDARCFPAN----GACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHP 375 Query: 639 VKGECHCSTGWGGVNC------ETPLPVCQEQCS--GHGTFLLDAGVCSCDPKWTGSDCS 690 + GEC C GW G++C +T P CQE C G +G+C C P +TG C+ Sbjct: 376 MNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCA 435 Query: 691 TELCT-----MECGSHGVCSRGI--------CQCEEGWVGPTCEER--------SCHS-- 727 + LC + C + C I C C+EGW C SC++ Sbjct: 436 S-LCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASC 494 Query: 728 HCTEHGQC--KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVC 785 C C + G C C+PGW G HC + +GC C + D C C Sbjct: 495 QCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQC 554 Query: 786 QVGWSGTGCNV-VMEMLCGDNLDNDGDGLTDCVDPDCC--QQSNC-----YISPLCQGSP 837 Q GW G C++ E L G N N C + C + NC + P CQ S Sbjct: 555 QAGWMGARCHLSCPEGLWGVNCSN----TCTCKNGGTCLPENGNCVCAPGFRGPSCQRSC 610 Query: 838 DP 839 P Sbjct: 611 QP 612 Score = 116 bits (291), Expect = 3e-25 Identities = 94/335 (28%), Positives = 119/335 (35%), Gaps = 68/335 (20%) Query: 530 DCSTNCNGNGECI--SGHCHCFPGFLGPDCARD--------SCPVLCGGNG---EYEKGH 576 D +C N C SG C C G P+C + +C C +G + + G Sbjct: 145 DKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA 204 Query: 577 CVCRHGWKGPECDVPEEQ------CIDPTCFGHGTCIM---GVCICVPGYKGEICE---E 624 C C GP CDV Q C +G G C C PG+ G IC Sbjct: 205 CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCP 264 Query: 625 EDCLDPMCS------NHGICVK--GECHCSTGWGGVNCETPLPV------CQE--QCSGH 668 E P CS N G+C + G+C C+ G+ G C PV C E C+ Sbjct: 265 EGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPD 324 Query: 669 GTFLLDAGVCSCDPKWTGSDCSTELCT-----MECGSHGVCSR----------GICQCEE 713 G C C+ +TG C+ LC + C + C R G C C Sbjct: 325 ARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLP 384 Query: 714 GWVGPTCEER--------SCHSHCT-EHG---QCKDGKCECSPGWEGDHCTIAHYLDAVR 761 GW G C E C HC HG Q G C+C+PG+ G HC D Sbjct: 385 GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYG 444 Query: 762 DGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 C C CVC+ GW C+V Sbjct: 445 VNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV 479 Score = 115 bits (289), Expect = 5e-25 Identities = 96/334 (28%), Positives = 123/334 (36%), Gaps = 74/334 (22%) Query: 531 CSTNCNGNGECIS-GHCHCFPGFLGPDCARDSCPVL----------CGGNG--EYEKGHC 577 C+ C +G C++ C C PG+ G DC+ + P + CG N + + G C Sbjct: 105 CAQECV-HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVC 163 Query: 578 VCRHGWKGPECDVP-EEQCIDPTCFGHGTC-------IMGVCICVPGYKGEICEEEDCLD 629 C G + P C P P C C G C C G C + C Sbjct: 164 SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSC-DVSCSQ 222 Query: 630 ----------PMCSNHGI--CVKGECHCSTGWGGVNCETPLPV------CQEQCSGHGTF 671 C N G+ +G C C GW G C P P C ++C H Sbjct: 223 GTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG 282 Query: 672 LLD--AGVCSCDPKWTGSDCSTEL--------C--TMECGSHGVC--SRGICQCEEGWVG 717 L D G C C P +TG C E C T +C C + G C CE G+ G Sbjct: 283 LCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTG 342 Query: 718 PTCEER---------SCHSHCT---EHG-QC--KDGKCECSPGWEGDHCTIAHYLDAVRD 762 C +R SC + CT EH C +G+C C PGW G HC + D Sbjct: 343 DRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGP 402 Query: 763 GCPG--LCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 GC LC G C C C G++G C Sbjct: 403 GCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHC 434 Score = 73.6 bits (179), Expect = 3e-12 Identities = 55/186 (29%), Positives = 70/186 (37%), Gaps = 52/186 (27%) Query: 530 DCSTNCN--GNGECI--SGHCHCFPGFLGPDCARDSC----------PVLCGGNG--EYE 573 +CS C G C+ +G+C C PGF GP C R SC P C + Sbjct: 575 NCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQR-SCQPGRYGKRCVPCKCANHSFCHPS 633 Query: 574 KGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCS 633 G C C GW GP+C P C PG+ GE C + C C Sbjct: 634 NGTCYCLAGWTGPDCSQP---------------------CPPGHWGENC-AQTC---QCH 668 Query: 634 NHGIC--VKGECHCSTGWGGVNCETPLPV------CQE--QCSGHGTFLLDAGVCSCDPK 683 + G C G C C GW G +C P+ C + QC + G C C P Sbjct: 669 HGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPG 728 Query: 684 WTGSDC 689 +G+ C Sbjct: 729 HSGAPC 734 Score = 42.0 bits (97), Expect = 0.008 Identities = 43/161 (26%), Positives = 55/161 (34%), Gaps = 34/161 (21%) Query: 693 LCTMECGSHGVC-SRGICQCEEGWVGPTCEER--------SCHSHCT--EHGQC--KDGK 739 LC EC HG C + CQC GW G C C C+ + C K G Sbjct: 104 LCAQEC-VHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGV 162 Query: 740 CECSPGWEGDH----CTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 795 C C G + + CT +Y A + C C G D C C +G C+ Sbjct: 163 CSCPSGLQPPNCLQPCTPGYYGPACQFRCQ--CHG---APCDPQTGACFCPAERTGPSCD 217 Query: 796 VVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGS 836 V + G C CQ + +P QGS Sbjct: 218 VSC---------SQGTSGFFCPSTHSCQNGGVFQTP--QGS 247 Score = 40.4 bits (93), Expect = 0.024 Identities = 23/91 (25%), Positives = 29/91 (31%), Gaps = 6/91 (6%) Query: 704 CSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDG 763 C G + G+ P C + H C QC +C PGW GD C+ Sbjct: 90 CCHGFYE-SRGFCVPLCAQECVHGRCVAPNQC-----QCVPGWRGDDCSSECAPGMWGPQ 143 Query: 764 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 C C + D C C G C Sbjct: 144 CDKPCSCGNNSSCDPKSGVCSCPSGLQPPNC 174 >gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] Length = 1541 Score = 127 bits (320), Expect = 1e-28 Identities = 96/335 (28%), Positives = 126/335 (37%), Gaps = 71/335 (21%) Query: 530 DCSTNCN-GNGEC--ISGHCHCFPGFLGPDCARD--------SCPVLC-----GGNGEYE 573 +CS++C+ G C ++G C C PG G DC D C +C + E Sbjct: 739 NCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPE 798 Query: 574 KGHCVCRHGWKGPEC-DVPEEQCIDPTCF--------GHGTCIMGVCICVPGYKGEICEE 624 G C+C G+ G C DV P+C GH G C C PG+ G C+ Sbjct: 799 TGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQR 858 Query: 625 E--------DCLDPM-CS-NHGIC--VKGECHCSTGWGGVNCETPLPV------CQEQCS 666 DC P CS HG C + G C C G+ G CE P C+++C Sbjct: 859 ACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQ 918 Query: 667 GHGTFLLD--AGVCSCDPKWTGSDCS------------TELCTMECGSHGVCSRGICQCE 712 D +G C+C W G+ C C G+ G C C Sbjct: 919 CQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCP 978 Query: 713 EGWVGPTCEERSCHSH-----CTEHGQCKDG--------KCECSPGWEGDHCTIAHYLDA 759 G GP C E +C +H C++ C +G +C C+PGW G C A Sbjct: 979 AGRRGPRCAE-TCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGL 1037 Query: 760 VRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 D C C T D HC C GW+G C Sbjct: 1038 YGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLAC 1072 Score = 114 bits (286), Expect = 1e-24 Identities = 103/372 (27%), Positives = 136/372 (36%), Gaps = 95/372 (25%) Query: 529 DDCSTNCNGNGE---C--ISGHCHCFPGFLGPDCAR--------DSCPVLCG----GNGE 571 +DC+ C GE C +G C C G+ GP C + C LCG G+ + Sbjct: 1169 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD 1228 Query: 572 YEKGHCVCRHGWKGPECDVPEEQC-IDPTCF-----GHGTC---IMGVCICVPGYKGEIC 622 G C C G+ G +C++ Q P C G G + G C+C PG G C Sbjct: 1229 AATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC 1288 Query: 623 E------------EEDCLDPMCSNHGIC--VKGECHCSTGWGGVNCETPLP------VCQ 662 E E C C N G+C G C C GW G +CE P C Sbjct: 1289 ERGCPQNRFGVGCEHTC---SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACH 1345 Query: 663 EQCSGHGTFLLD--AGVCSCDPKWTGSDCSTELCTMEC--GSHGVCSRGICQCEEGWVGP 718 +CS H + G C C P + G + C C G HG +G+C C+ G Sbjct: 1346 LECSCHNNSTCEPATGTCRCGPGFYG-----QACEHPCPPGFHGAGCQGLCWCQHG---A 1397 Query: 719 TCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQ 778 C+ S G+C C G+ G C + +GC C +G D Sbjct: 1398 PCDPIS-------------GRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDP 1444 Query: 779 NGWHCVCQVGWSGTGCNV-----------VMEMLCGDNLDNDG-DGLTDCVDPDCCQQSN 826 C+C G SG CN+ + CG D D G CVD Sbjct: 1445 VTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG------- 1497 Query: 827 CYISPLC-QGSP 837 Y+ P C +G P Sbjct: 1498 -YMGPTCREGGP 1508 Score = 110 bits (275), Expect = 2e-23 Identities = 97/341 (28%), Positives = 125/341 (36%), Gaps = 79/341 (23%) Query: 530 DCSTNC---NGNG-ECISGHCHCFPGFLGPDC------------ARDSCPVLCGGNGEYE 573 +CS C NG + + G CHC PG++GP C R SC GG + Sbjct: 998 NCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPV 1057 Query: 574 KGHCVCRHGWKGPECDVPEEQCI----------DPTCFGHGTC--IMGVCICVPGYKGEI 621 GHC C GW G C E++C+ C G C G C+C G+ G+ Sbjct: 1058 SGHCACPEGWAGLAC---EKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDK 1114 Query: 622 CEEEDCL----DPMCSNHGIC--------VKGECHCSTGWGGVNCETPLPV------CQE 663 C + CL C+ C V G C C G+ G CE P C + Sbjct: 1115 C-QSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQ 1173 Query: 664 --QCSGHGTFLLDA-GVCSCDPKWTGSDCSTEL--------CTMECG--SHGVC--SRGI 708 QC G A G CSC + G C C CG + G C + G Sbjct: 1174 MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233 Query: 709 CQCEEGWVGP----TCEERSCHSHCTEHGQCKD--------GKCECSPGWEGDHCTIAHY 756 C+C G++G TC + +CT C G C C PG G C Sbjct: 1234 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP 1293 Query: 757 LDAVRDGCPGLC-FGNGRCTLDQNGWHCVCQVGWSGTGCNV 796 + GC C NG NG C C +GW+G C + Sbjct: 1294 QNRFGVGCEHTCSCRNGGLCHASNG-SCSCGLGWTGRHCEL 1333 Score = 104 bits (260), Expect = 1e-21 Identities = 115/448 (25%), Positives = 140/448 (31%), Gaps = 143/448 (31%) Query: 534 NCNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEK---------------GH 576 NC G C + G C C PG G C +CP G G E+ G Sbjct: 612 NCANRGRCHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS 670 Query: 577 CVCRHGWKGPECDVP-EEQCIDPTCFGHGTCIMGV------------------------- 610 C C+ G++G C E P C+ TC +GV Sbjct: 671 CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE 730 Query: 611 ---------------------------CICVPGYKGEICEEEDC-----------LDPMC 632 C C PG GE C E DC + P C Sbjct: 731 CPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC-EADCPEGRWGLGCQEICPAC 789 Query: 633 SNHGIC--VKGECHCSTGWGGVNCETPLPV------CQEQCS--GHGTFLLDAGVCSCDP 682 + C G C C G+ G C+ P CQ +CS G G CSC P Sbjct: 790 QHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAP 849 Query: 683 KWTGSDCSTEL--------CTMEC---GSHGVCS--RGICQCEEGWVGPTCEERSCHSH- 728 WTG C C+ C HG C G+C CE G+VGP CE++ H Sbjct: 850 GWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHF 909 Query: 729 ---CTEHGQCK--------DGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLD 777 C + QC+ G C C GW G C A C C D Sbjct: 910 GPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACD 969 Query: 778 QNGWHCVCQVGWSGTGC-----------NVVMEMLCGDNLDNDG-DGLTDC----VDPDC 821 C+C G G C N C + D G C + P C Sbjct: 970 AVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC 1029 Query: 822 CQQ-------SNCYISPLCQ--GSPDPL 840 Q NC S LCQ G+ DP+ Sbjct: 1030 LQACPAGLYGDNCRHSCLCQNGGTCDPV 1057 Score = 102 bits (255), Expect = 4e-21 Identities = 96/345 (27%), Positives = 119/345 (34%), Gaps = 93/345 (26%) Query: 532 STNCNGNGEC--ISGHCHCFPGFLGPDCARDSCP-----------VLCGGNGEYEK--GH 576 S +C G C ++G C C PG G +C D CP C G + G Sbjct: 567 SCSCQNGGTCDSVTGACRCPPGVSGTNC-EDGCPKGYYGKHCRKKCNCANRGRCHRLYGA 625 Query: 577 CVCRHGWKGPECDVP-EEQCIDPTCFGHGTCIM----------GVCICVPGYKGEICEEE 625 C+C G G C + P C C+ G C C G++GE C+ E Sbjct: 626 CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE 685 Query: 626 ---DCLDPMCSNHGIC--------VKGEC--HCSTGWGGVNCETPLPV------CQEQCS 666 P C C V GEC C G+ G +C PV C CS Sbjct: 686 CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 745 Query: 667 -----GHGTFLLDAGVCSCDPKWTGSDCSTEL---------------------CTMECGS 700 HG G C C P TG DC + C E G+ Sbjct: 746 CGGAPCHGV----TGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA 801 Query: 701 HGVCSRGI----CQ--CEEGWVGPTCEERSCHSHCTEHGQC--KDGKCECSPGWEGDHCT 752 +C G CQ C GW GP+C+ R C G C G C C+PGW G C Sbjct: 802 -CLCLPGFVGSRCQDVCPAGWYGPSCQTR---CSCANDGHCHPATGHCSCAPGWTGFSCQ 857 Query: 753 IAHYLDAVRDGCPGLC---FGNGRCTLDQNGWHCVCQVGWSGTGC 794 A C C G+G C D C+C+ G+ G C Sbjct: 858 RACDTGHWGPDCSHPCNCSAGHGSC--DAISGLCLCEAGYVGPRC 900 Score = 75.1 bits (183), Expect = 9e-13 Identities = 89/389 (22%), Positives = 116/389 (29%), Gaps = 133/389 (34%) Query: 548 CFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPEC------DVPEEQC-IDPTC 600 C G DC+ GG C C GW G C D + C +C Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570 Query: 601 FGHGTC--IMGVCICVPGYKGEICEE--------EDC----------------------- 627 GTC + G C C PG G CE+ + C Sbjct: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630 Query: 628 ---------------LDPMCSNHGICVK----------GECHCSTGWGGVNCETPL---- 658 P CS CV+ G C C G+ G C+ Sbjct: 631 GLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY 690 Query: 659 --PVCQEQCSGHGTFLLD--AGVCS--CDPKWTGSDCSTEL--------CTMECGSHGVC 704 P C + C+ D +G C C + G DC E C+ C G Sbjct: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAP 750 Query: 705 SRGI---CQCEEGWVGPTCE------------ERSCHSHCTEHGQC--KDGKCECSPGWE 747 G+ C+C G G CE + C + C +C + G C C PG+ Sbjct: 751 CHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPA-CQHAARCDPETGACLCLPGFV 809 Query: 748 GDHCTIAHYLDAVRDGCPGLCFG---NGRCTLDQNG------WHCVCQVGWSGTGCNVVM 798 G C +D CP +G RC+ +G HC C GW+G C Sbjct: 810 GSRC---------QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRAC 860 Query: 799 EMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827 + T PDC NC Sbjct: 861 D--------------TGHWGPDCSHPCNC 875 Score = 61.2 bits (147), Expect = 1e-08 Identities = 52/207 (25%), Positives = 69/207 (33%), Gaps = 60/207 (28%) Query: 663 EQCSGHGTFLLDAGVCSCDPKWTGSDCSTELC-----------TMECGSHGVCS--RGIC 709 + C GT LL C C WTG C+ E C + C + G C G C Sbjct: 525 DDCRNGGTCLLGLDGCDCPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583 Query: 710 QCEEGWVGPTCEE--------RSCHS--HCTEHGQCKD--GKCECSPGWEGDHCTIAHYL 757 +C G G CE+ + C +C G+C G C C PG G C + Sbjct: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLT--- 640 Query: 758 DAVRDGCPGLCFGNG-----RC------TLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNL 806 CP FG G +C + D+ C C+ G+ G C E+ Sbjct: 641 ------CPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECEL------ 688 Query: 807 DNDGDGLTDCVDPDCCQQSNCYISPLC 833 P C Q C + C Sbjct: 689 --------GYFGPGCWQACTCPVGVAC 707 Score = 55.1 bits (131), Expect = 9e-07 Identities = 70/270 (25%), Positives = 95/270 (35%), Gaps = 71/270 (26%) Query: 620 EICEEEDCLDPMCSNHGICVKGE---CHCSTGWGGVNCETPLPVCQEQ---CSGHGTFLL 673 E C +C +C + G CV G CHC G+ G C+ + C+ C Sbjct: 121 EGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTP 180 Query: 674 DAGVCSCDPKWT-GSDCSTELCTMECG-SHGVC---------SRGICQCEEGWV----GP 718 + +C C P + +D T L C +G C +R CQC G+ G Sbjct: 181 GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGR 240 Query: 719 TCEERS-C---HSHCTEHGQCKDG--KCECSPGWE----GDHCTIAHYLDAVRDGCPGLC 768 C RS C + C Q G +CEC G++ G C + V + GL Sbjct: 241 HCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKAC------EDVDECAAGLA 294 Query: 769 FGNGRCTLDQNGWHCVCQVGWS----GTGC-NVVMEM----------------------L 801 C Q + CVC G+ G C + ME+ L Sbjct: 295 QCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPL 354 Query: 802 C----GDNLDNDGD---GLTDCVDPDCCQQ 824 C G LD D + DC D CCQQ Sbjct: 355 CTCPRGYELDTDQRTCIDVDDCADSPCCQQ 384 Score = 52.8 bits (125), Expect = 5e-06 Identities = 88/356 (24%), Positives = 127/356 (35%), Gaps = 92/356 (25%) Query: 530 DCSTN-CNGNGECISGH---CHCFPGFLGPDCAR--DSCPVLCGG--------NGEYEKG 575 +CS + C G C+ G CHC PGF GP C D C GG G Y Sbjct: 127 ECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSY--- 183 Query: 576 HCVCRHGWKGPECDVPEEQCIDPTCFGHGTC---------IMGVCICVPGYK----GEIC 622 C C+ G++ D I+ G+G C C C PG++ G C Sbjct: 184 LCECKPGFR-LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 242 Query: 623 EEEDCLDPMCSNHGIC------VKG--ECHCSTGW----GGVNCE------TPLPVCQEQ 664 P + +G C V+G C C G+ G CE L C Sbjct: 243 VRR---SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG 299 Query: 665 C-SGHGTFLLDAGVCSCDPKW----TGSDC---STELCTMECGSHGVCSRG--------I 708 C + G+F C C + G C E+ ++G CS G + Sbjct: 300 CLNTQGSF-----KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPL 354 Query: 709 CQCEEGWVGPTCEERSC--HSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPG 766 C C G+ T ++R+C C + C+ C +PG C + L A GC Sbjct: 355 CTCPRGYELDT-DQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADGCGCED 412 Query: 767 L--CFGN-----GRCTLDQNGWHCVCQVGW----SGTGCNVVMEMLCGDNLDNDGD 811 + C + CT + C C+ G+ GC+ + E + +D DG+ Sbjct: 413 VDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPM----VDLDGE 464 Score = 37.4 bits (85), Expect = 0.20 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 3/44 (6%) Query: 534 NCNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKG 575 +C G +C +SG CHC G++GP C R+ P+ N +G Sbjct: 1478 DCGGGADCDPVSGQCHCVDGYMGPTC-REGGPLRLPENPSLAQG 1520 Score = 35.0 bits (79), Expect = 1.0 Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 19/96 (19%) Query: 705 SRGICQCEEGWVGPTCEERSCHSHCT-----EHGQCKDGK---CECSPGWEGDHCTIAHY 756 +R + +C GW+ EE + C+ G+C G C C PG++G C + Sbjct: 104 ARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRC--QYD 161 Query: 757 LDAVR---DGCPGLCFGNGRCTLDQNGWHCVCQVGW 789 +D R GC RC + C C+ G+ Sbjct: 162 VDECRTHNGGC------QHRCVNTPGSYLCECKPGF 191 >gi|21704279 jagged 2 isoform b precursor [Homo sapiens] Length = 1200 Score = 122 bits (307), Expect = 4e-27 Identities = 88/285 (30%), Positives = 119/285 (41%), Gaps = 32/285 (11%) Query: 575 GHCVCRHGWKGPECDVPEEQCIDPTCFGHGTC-IMGVCICVPGYKGEICEEEDCLDPMCS 633 G+ C GW G EC E C HG C + G C C G++G C+E C+ Sbjct: 227 GNKACMDGWMGKECK--EAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDE--CVPYPGC 282 Query: 634 NHGICVKG-ECHCSTGWGGVNCETPLPVC--QEQCSGHGTFL---LDAGVCSCDPKWTGS 687 HG CV+ +C+C T WGG+ C+ L C C+ GT + D C+C ++G Sbjct: 283 VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGR 342 Query: 688 DC--STELCTME-CGSHGVC----SRGICQCEEGWVGPTCE---ERSCHSHCTEHGQCKD 737 +C + CT C + G C S C C GW GPTC + + C G C D Sbjct: 343 NCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVD 402 Query: 738 G----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTG 793 +C C W G C LD + C G C G C NG+ CVC G+ G Sbjct: 403 QVDGFECICPEQWVGATC----QLDV--NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRH 456 Query: 794 CNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPD 838 C + + C + + G D D C + PLC+ D Sbjct: 457 CELERDE-CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVD 500 Score = 120 bits (300), Expect = 2e-26 Identities = 90/302 (29%), Positives = 116/302 (38%), Gaps = 41/302 (13%) Query: 531 CSTNCNG-NGEC-ISGHCHCFPGFLGPDCARDSCPVL--CGGNGEYEKGHCVCRHGWKGP 586 C CN +G C + G C C G+ G C D C C E C C W G Sbjct: 245 CKQGCNLLHGGCTVPGECRCSYGWQGRFC--DECVPYPGCVHGSCVEPWQCNCETNWGGL 302 Query: 587 ECDVPEEQC-IDPTCFGHGTCIMGV-----CICVPGYKGEICE--EEDCLDPMCSNHGIC 638 CD C C GTCI C C GY G CE E C C+N G C Sbjct: 303 LCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC 362 Query: 639 VK----GECHCSTGWGGVNCETPLPVC-QEQCSGHGTFL--LDAGVCSCDPKWTGSDCST 691 + ECHC +GW G C + C C+ GT + +D C C +W G+ C Sbjct: 363 HEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL 422 Query: 692 EL--CTMECGSHGVCSRGI----CQCEEGWVGPTCE---ERSCHSHCTEHGQCKD----G 738 ++ C +C G C + C C G+ G CE + S C G C+D Sbjct: 423 DVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGF 482 Query: 739 KCECSPGWEGDHCTIAHYLDAVRDGC-PGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVV 797 C C G+ G C + D C P C RC + ++C C + G C+V Sbjct: 483 HCHCPQGFSGPLCEVD------VDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVP 536 Query: 798 ME 799 E Sbjct: 537 RE 538 Score = 112 bits (281), Expect = 4e-24 Identities = 111/375 (29%), Positives = 137/375 (36%), Gaps = 66/375 (17%) Query: 519 FVLTTAIEIMDDC-STNCNGNGECISG----HCHCFPGFLGPDC---ARDSCPVLCGGNG 570 F T E +DDC C G CI C C G+ G C D P C G Sbjct: 590 FTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG 649 Query: 571 E----YEKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG----VCICVPGYKGEIC 622 +C C GWKG C E QC TC GTC C C PG+KG C Sbjct: 650 RCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTC 709 Query: 623 ---EEEDCLDPMCSNHGICVKG----ECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDA 675 + CL C N G CV C C GW G C C +G +D Sbjct: 710 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD- 768 Query: 676 GV----CSCDPKWTGSDCS---TELCTMECGSHGVCSRGI----CQCEEGWVGPTCEE-- 722 GV C C P + G DC E + C C I C C G GP C+E Sbjct: 769 GVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 828 Query: 723 ---RSCHSHCT--EHG----------QCKDGKCECSPGWEG-DHCTIAHYLDAVRDGCPG 766 RSC S T HG +C DG+ +CS W G C +A +A+ CP Sbjct: 829 GFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCP- 887 Query: 767 LCFGNGRCTLDQNGWHCV---CQVGWSGTGCNVVMEMLC---GDNLDNDGDGLTDCVDPD 820 G+ L++ C+ C+ W G C +LDN+ LT + D Sbjct: 888 ----LGQRCLEKAPGQCLRPPCE-AWGECGAEEPPSTPCLPRSGHLDNNCARLTLHFNRD 942 Query: 821 CCQQSNCYISPLCQG 835 Q + +C G Sbjct: 943 HVPQGTT-VGAICSG 956 Score = 111 bits (277), Expect = 1e-23 Identities = 103/412 (25%), Positives = 143/412 (34%), Gaps = 114/412 (27%) Query: 535 CNGNGECISGH-----CHCFPGFLGPDC--ARDSC---PVLCGGN-GEYEKG-HCVCRHG 582 C G CI+ C C G+ G +C A +C P GG+ E G C C G Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376 Query: 583 WKGPECDVPEEQCIDPTCFGHGTCIMGV-------------------------------- 610 W GP C + ++C C GTC+ V Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGT 436 Query: 611 ---------CICVPGYKGEIC--EEEDCLDPMCSNHGICVK----GECHCSTGWGGVNCE 655 C+C G+ G C E ++C C + G+C CHC G+ G CE Sbjct: 437 CKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 496 Query: 656 TPLPVCQEQCSGHGT--FLLDAG-VCSCDPKWTGSDCST--ELC---------------- 694 + +C+ +G + L+ C+C + G +CS E C Sbjct: 497 VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAG 556 Query: 695 --------TMECGSHGVC-----SRGICQCEEGWVGPTCEER--SCHSH-CTEHGQCKDG 738 + CG HG C C C+ G+ G C E C C G C D Sbjct: 557 PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDE 616 Query: 739 ----KCECSPGWEGDHCTIAHYLDAVRDGC-PGLCFGNGRCTLDQNGWHCVCQVGWSGTG 793 +C C GWEG+ C D + C P C GRC N ++C C GW G Sbjct: 617 VDAFRCFCPSGWEGELC------DTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKT 670 Query: 794 CNVVMEMLCGDNLDNDGDGLTD------CVDPDCCQQSNCYISPLCQGSPDP 839 C+ E C ++G D C P + S C ++ P+P Sbjct: 671 CH-SREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP 721 Score = 65.5 bits (158), Expect = 7e-10 Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 41/213 (19%) Query: 661 CQEQCSGHGTFLLDA-GVCSCDPKWTGSDCSTELCTMECGS-HGVCS-RGICQCEEGWVG 717 C+ + G + D G +C W G +C +C C HG C+ G C+C GW G Sbjct: 211 CRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQG 270 Query: 718 PTCEERSCHSHCTEHGQC-KDGKCECSPGWEG-------DHCTIAHYL-----------D 758 C+E + C HG C + +C C W G ++C H D Sbjct: 271 RFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPD 329 Query: 759 AVRDGCP-----------------GLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEML 801 R CP C G C +G+ C C GWSG C + ++ Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE- 388 Query: 802 CGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 834 C N G D VD C ++ CQ Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQWVGATCQ 421 >gi|9506545 delta-like 4 protein precursor [Homo sapiens] Length = 685 Score = 118 bits (296), Expect = 7e-26 Identities = 94/340 (27%), Positives = 131/340 (38%), Gaps = 65/340 (19%) Query: 529 DDCSTNCNGNGECIS-------GHCHCFPGFLGPDCARDSCPVLCGGNGEY--EKGHCVC 579 D+CS C + G+ C PG+ G C + C C Y + C+C Sbjct: 182 DNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLC 241 Query: 580 RHGWKGPECDVPEEQCIDPTCFGHGTCIMG-VCICVPGYKGEICEEEDCLDPMCSNHGIC 638 R GW+G C+ +CI HGTC C C G+ G C+++ C++H C Sbjct: 242 RPGWQGRLCN----ECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDL---NYCTHHSPC 294 Query: 639 VKGE-----------CHCSTGWGGVNCETPLPVCQEQ-CSGHGTFL--LDAGVCSCDPKW 684 G C C G+ GV+CE L C C G+ D C C P + Sbjct: 295 KNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGY 354 Query: 685 TGSDC--STELCT-MECGSHGVC------SRGICQCEEGWVGPTCEER--SCHSH-CTEH 732 G C ST C C + G C + C+C + G CE++ C S+ C Sbjct: 355 YGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANG 414 Query: 733 GQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVG 788 GQC + C C PG+ G +C + H D R+ C G C +NG C C G Sbjct: 415 GQCLNRGPSRMCRCRPGFTGTYCEL-HVSDCARNPCAH----GGTCHDLENGLMCTCPAG 469 Query: 789 WSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCY 828 +SG C V + C C ++ CY Sbjct: 470 FSGRRCEV-------------RTSIDACASSPCFNRATCY 496 Score = 97.1 bits (240), Expect = 2e-19 Identities = 78/256 (30%), Positives = 103/256 (40%), Gaps = 31/256 (12%) Query: 578 VCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHG 636 +C + G C ++ D FGH C G C+PG+ GE C++ CL +G Sbjct: 174 ICSDNYYGDNCSRLCKKRNDH--FGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNG 231 Query: 637 ICVK-GECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTEL-- 693 C K EC C GW G C +P C HGT C+CD W G C +L Sbjct: 232 YCSKPAECLCRPGWQGRLCNECIP--HNGCR-HGT-CSTPWQCTCDEGWGGLFCDQDLNY 287 Query: 694 CT--MECGSHGVCSRG-----ICQCEEGWVGPTCEER--SCHSH-CTEHGQCKDGK---- 739 CT C + CS C C G+ G CE C S+ C G CKD + Sbjct: 288 CTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYH 347 Query: 740 CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNG--WHCVCQVGWSGTGCNVV 797 C C PG+ G HC H + D CF G C G + C C ++G+ C Sbjct: 348 CLCPPGYYGLHC--EHSTLSCAD---SPCFNGGSCRERNQGANYACECPPNFTGSNCEKK 402 Query: 798 MEMLCGDNLDNDGDGL 813 ++ + N G L Sbjct: 403 VDRCTSNPCANGGQCL 418 Score = 90.1 bits (222), Expect = 3e-17 Identities = 64/220 (29%), Positives = 88/220 (40%), Gaps = 34/220 (15%) Query: 535 CNGNGECISGHCHCFPGFLGPDCAR-----DSCPVLCGGN-GEYEKG-HCVCRHGWKGPE 587 C+ +G+ S C C PG+ G DC DS P GG+ + E G HC+C G+ G Sbjct: 300 CSNSGQR-SYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLH 358 Query: 588 CDVPEEQCIDPTCFGHGTC------IMGVCICVPGYKGEICEE--EDCLDPMCSNHGICV 639 C+ C D CF G+C C C P + G CE+ + C C+N G C+ Sbjct: 359 CEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCL 418 Query: 640 ----KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG---VCSCDPKWTGSDCSTE 692 C C G+ G CE + C HG D +C+C ++G C Sbjct: 419 NRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVR 478 Query: 693 LCTMECGSHGVCSRG-----------ICQCEEGWVGPTCE 721 C S +R +C C G+VG CE Sbjct: 479 TSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518 Score = 76.3 bits (186), Expect = 4e-13 Identities = 60/233 (25%), Positives = 88/233 (37%), Gaps = 53/233 (22%) Query: 645 CSTGWGGVNCETPLPVCQEQCSGHGTFLLDA-GVCSCDPKWTGSDCSTELCTMECGS-HG 702 CS + G NC +C+++ G ++ G SC P WTG C +C C +G Sbjct: 175 CSDNYYGDNCSR---LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNG 231 Query: 703 VCSRGI-CQCEEGWVGPTCEERSCHSHCTEHGQCKDG-KCECSPGWEG-------DHCT- 752 CS+ C C GW G C E H+ C HG C +C C GW G ++CT Sbjct: 232 YCSKPAECLCRPGWQGRLCNECIPHNGC-RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTH 290 Query: 753 --------------IAHYLDAVRDGCPGL-------------CFGNGRCTLDQNGWHCVC 785 Y R G G+ C G C ++G+HC+C Sbjct: 291 HSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLC 350 Query: 786 QVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPD 838 G+ G C + C D + C + C++ N + C+ P+ Sbjct: 351 PPGYYGLHCE-HSTLSCAD---------SPCFNGGSCRERNQGANYACECPPN 393 Score = 55.8 bits (133), Expect = 6e-07 Identities = 41/148 (27%), Positives = 55/148 (37%), Gaps = 25/148 (16%) Query: 534 NCNGNGECISGHCHCFPGFLGPDCAR--DSC---PVLCGGN--GEYEKGHCVCRHGWKGP 586 +C + + C C P F G +C + D C P GG C CR G+ G Sbjct: 376 SCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGT 435 Query: 587 ECDVPEEQCIDPTCFGHGTC------IMGVCICVPGYKGEICEE----EDCLDPMCSNHG 636 C++ C C GTC +M C C G+ G CE + C C N Sbjct: 436 YCELHVSDCARNPCAHGGTCHDLENGLM--CTCPAGFSGRRCEVRTSIDACASSPCFNRA 493 Query: 637 ICVKG------ECHCSTGWGGVNCETPL 658 C C+C G+ G CE P+ Sbjct: 494 TCYTDLSTDTFVCNCPYGFVGSRCEFPV 521 >gi|116235485 delta-notch-like EGF repeat-containing transmembrane [Homo sapiens] Length = 737 Score = 116 bits (291), Expect = 3e-25 Identities = 96/373 (25%), Positives = 141/373 (37%), Gaps = 61/373 (16%) Query: 487 LTSLQETGFIEYMDQ-----GPWYLAFYNDGKKMEQVFVLTTAIEIMDDC--------ST 533 +T LQ +G + +++ ++ F ND V + T + + C Sbjct: 258 VTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDL 317 Query: 534 NCNGNGECISG------HCHCFPGFLGPDCAR-DSCP-------VLCGGNGEYEKGH--- 576 C+G G+C + C C ++G C D+C C E + G Sbjct: 318 ECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFT 377 Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--EDCLDP 630 CVC G+ G C + CI C TCI + C C GY G CEE + C Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437 Query: 631 MCSNHGIC----VKGECHCSTGWGGVNCETPLPVCQEQCSGHGTF--LLDAGVCSCDPKW 684 C N+G C V C+CS G+ G C + C HGT + + C CDP + Sbjct: 438 PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGY 497 Query: 685 TGSDCS---TELCTMECGSHGVCSRGI----CQCEEGWVGPTCE-------ERSCHSHCT 730 G C E + C + C + C C + G CE SC + T Sbjct: 498 HGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGAT 557 Query: 731 EHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWS 790 +G C C+PG+ G+ C I + + C G C NG++C C GW Sbjct: 558 CDSDGLNGTCICAPGFTGEECDID-----INECDSNPCHHGGSCLDQPNGYNCHCPHGWV 612 Query: 791 GTGCNVVMEMLCG 803 G C + ++ G Sbjct: 613 GANCEIHLQWKSG 625 Score = 54.3 bits (129), Expect = 2e-06 Identities = 45/173 (26%), Positives = 67/173 (38%), Gaps = 40/173 (23%) Query: 696 MECGSHGVCSRG------ICQCEEGWVGPTCEE------RSCHSH--CTEHGQCKDGK-- 739 +EC G C+ C CEE +VG CEE + C ++ C + + +DG Sbjct: 317 LECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNF 376 Query: 740 -CECSPGWEGDHCTIAH---YLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 795 C C PG+ G+ C LD R+G C +G+ C C G+ G+ C Sbjct: 377 TCVCLPGYTGELCQSKIDYCILDPCRNGAT--------CISSLSGFTCQCPEGYFGSACE 428 Query: 796 VVMEMLCGDNLDNDGDGLTDCV-----------DPDCCQQSN-CYISPLCQGS 836 ++ N+G D V P C Q + C +SP G+ Sbjct: 429 EKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGT 481 Score = 36.6 bits (83), Expect = 0.35 Identities = 18/56 (32%), Positives = 23/56 (41%), Gaps = 9/56 (16%) Query: 577 CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMG--------VCICVPGYKGEICEE 624 C C G G C + + C C HG C +CIC GY+G CE+ Sbjct: 80 CTCPAGISGANCQLVADPCASNPCH-HGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134 Score = 36.2 bits (82), Expect = 0.45 Identities = 27/114 (23%), Positives = 35/114 (30%), Gaps = 25/114 (21%) Query: 609 GVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGH 668 G C P G +C DP C C G G NC+ C H Sbjct: 46 GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH 105 Query: 669 GTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEE 722 G +CS+ + G +C C EG+ GP CE+ Sbjct: 106 G------------------NCSSSSSSSSDGY-------LCICNEGYEGPNCEQ 134 Score = 33.5 bits (75), Expect = 2.9 Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 13/60 (21%) Query: 611 CICVPGYKGEICEEEDCLDPMCSN---HGICVKGE--------CHCSTGWGGVNCETPLP 659 C C G G C+ DP SN HG C C C+ G+ G NCE LP Sbjct: 80 CTCPAGISGANCQL--VADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALP 137 >gi|122937283 6720455I24Rik homolog [Homo sapiens] Length = 1413 Score = 116 bits (290), Expect = 3e-25 Identities = 97/362 (26%), Positives = 134/362 (37%), Gaps = 55/362 (15%) Query: 525 IEIMDDCSTNCNGNGECISG----HCHCFPGFLGPDC--ARDSCPVL-C--GGNGEYEKG 575 +++ + S C G C G C C GF GP C A+ C C GG + E G Sbjct: 310 LDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENG 369 Query: 576 H--CVCRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEEED--- 626 CVC+ G+ G C++ + C C G+C+ V C+C +KG CE D Sbjct: 370 SAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV 429 Query: 627 ---CLDPMCSNHGICVKGE----CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCS 679 CL C N G CV + C C G+ G++C +P E +G + +C Sbjct: 430 PDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ 489 Query: 680 CDPKWTGSDCSTELCTMECGSHGVCSRG----------ICQCEEGWVGPTCEERSCHSH- 728 C + G C E+ M C + C G +C C C S Sbjct: 490 CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDP 549 Query: 729 CTEHGQC----KDGKCECSPGWEGDHCTIA--HYLDAVRDGCPGLCFGNGRCTLDQNGWH 782 C G C CEC G+ G HC A H + G C G C +H Sbjct: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSS------GPCRNGGTCKEAGGEYH 603 Query: 783 CVCQVGWSGTGCNVVMEMLCGDNLDNDGD------GLTDCVDPDCCQQSNCYISPL-CQG 835 C C ++G C + C ++G G C P +C I+P C Sbjct: 604 CSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFR 663 Query: 836 SP 837 SP Sbjct: 664 SP 665 Score = 96.7 bits (239), Expect = 3e-19 Identities = 98/381 (25%), Positives = 126/381 (33%), Gaps = 84/381 (22%) Query: 528 MDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPE 587 +DD G G S P G C D C GN Y C C G+ G Sbjct: 255 IDDAQVRVGGCGHTTSVCLALRPCLNGGKCI-DDCVT---GNPSYT---CSCLSGFTGRR 307 Query: 588 CDVPEEQCIDPTCFGHGTCIMG-------------------------------------- 609 C + +C C GTC G Sbjct: 308 CHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVE 367 Query: 610 ----VCICVPGYKGEICE--EEDCLDPMCSNHGICV----KGECHCSTGWGGVNCET--- 656 VC+C GY G CE +DC C N G CV C C+ + G+ CET Sbjct: 368 NGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDH 427 Query: 657 PLP-VCQEQCSGHGTFLLDAG---VCSCDPKWTGSDCSTEL-CTMECGSHGVC---SRGI 708 P+P C +G +DA VC C + G DC + EC + G C + + Sbjct: 428 PVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTL 487 Query: 709 CQCEEGWVGPTCEERSCHSHCTEHGQCKDG----------KCECSPGWEGDHCTIAHYLD 758 CQC G+ G CE C + QC DG C C DH +H L Sbjct: 488 CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC----HTDH-NASHSLP 542 Query: 759 AVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVD 818 + D P CF G C + + C C G+ G C LC +G + Sbjct: 543 SPCDSDP--CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG 600 Query: 819 PDCCQQSNCYISPLCQ-GSPD 838 C + C+ G PD Sbjct: 601 EYHCSCPYRFTGRHCEIGKPD 621 Score = 95.9 bits (237), Expect = 5e-19 Identities = 96/335 (28%), Positives = 122/335 (36%), Gaps = 79/335 (23%) Query: 532 STNCNGNGECI----SGHCHCFPGFLGPDCARDSCPVLC-------GGN-----GEYEKG 575 S C G C S C C GF G C + + P LC GG GEY Sbjct: 547 SDPCFNGGSCDAHDDSYTCECPRGFHGKHCEK-ARPHLCSSGPCRNGGTCKEAGGEY--- 602 Query: 576 HCVCRHGWKGPECDVPE-EQCIDPTCFGHGTCIMGV----CICVPGYKGEICE--EEDCL 628 HC C + + G C++ + + C C GTC + C C PG+ G CE C Sbjct: 603 HCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCF 662 Query: 629 DPMCSNHGICVKGE----CHCSTGWGG------VNCETPLPVCQEQCSGHGTFLLDAGVC 678 C N G C + CHC G+ G V+C P V +GT L + Sbjct: 663 RSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALY 722 Query: 679 SCDPKWTGSDCSTELCTMECGSHGV-----------------CSRG----------ICQC 711 +CD G S C HGV C G +C C Sbjct: 723 ACD---RGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLC 779 Query: 712 EEGWVGPTCE-ERS-CHSH-CTEHGQCKDGK----CECSPGWEGDHCTIAHYLDAVRDGC 764 G+ G CE ER C +H C G C++ C C G+ G HC +DA D Sbjct: 780 STGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETE--VDAC-DSS 836 Query: 765 PGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVME 799 P C GRC + CVC + G C V + Sbjct: 837 P--CQHGGRCESGGGAYLCVCPESFFGYHCETVSD 869 Score = 91.7 bits (226), Expect = 9e-18 Identities = 95/331 (28%), Positives = 121/331 (36%), Gaps = 79/331 (23%) Query: 531 CSTN-CNGNGECISG----HCHCFPGFLGPDCA---RDSC---PVLCGGN-----GEYEK 574 CS+ C G C HC C F G C DSC P GG G+Y+ Sbjct: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYK- 642 Query: 575 GHCVCRHGWKGPECDVPEEQCIDPTCFGHGTC----IMGVCICVPGYKGEICEEE-DCLD 629 C C G+ G C++ C C GTC C C GY G C+ E DC Sbjct: 643 --CDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP 700 Query: 630 PMCSNHG--------ICVKGECHCSTGWG-------------GVNCETP----LPVCQEQ 664 P H + C G+ GV E P + C+ Q Sbjct: 701 PEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQ 760 Query: 665 CSGHGTFLLD--AG-VCSCDPKWTGSDCSTELCTMECGSHGVCSRG----------ICQC 711 HG D AG +C C + G+ C EL EC +H C G +C+C Sbjct: 761 PCLHGGSCQDRVAGYLCLCSTGYEGAHC--ELERDECRAH-PCRNGGSCRNLPGAYVCRC 817 Query: 712 EEGWVGPTCEER--SCHSH-CTEHGQCKDG----KCECSPGWEGDHCTIAHYLDAVRDGC 764 G+VG CE +C S C G+C+ G C C + G HC + V D C Sbjct: 818 PAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHC------ETVSDPC 871 Query: 765 -PGLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794 C G G C C C+VG++G C Sbjct: 872 FSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902 Score = 70.1 bits (170), Expect = 3e-11 Identities = 51/158 (32%), Positives = 69/158 (43%), Gaps = 19/158 (12%) Query: 555 PDCAR-DSC---PVLCGGNGEYEKGH--CVCRHGWKGPECDVPEEQCIDPTCFGHGTC-- 606 P C D C P L GG+ + C+C G++G C++ ++C C G+C Sbjct: 749 PQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRN 808 Query: 607 IMG--VCICVPGYKGEICEEE--DCLDPMCSNHGICVKGE----CHCSTGWGGVNCETPL 658 + G VC C G+ G CE E C C + G C G C C + G +CET Sbjct: 809 LPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVS 868 Query: 659 PVC-QEQCSGHGTFLLDAG--VCSCDPKWTGSDCSTEL 693 C C G G L G C+C +TG DC+ EL Sbjct: 869 DPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906 Score = 37.0 bits (84), Expect = 0.27 Identities = 41/144 (28%), Positives = 55/144 (38%), Gaps = 22/144 (15%) Query: 424 HHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFD-FVKLMDGKQLVKQDSKGSDDTQHSP 482 HHP LK A+ L + + P T TQ F +L+DG+ V GS + Sbjct: 1211 HHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARFGGSPSKAATV 1270 Query: 483 RNLILTSLQETGFIEYMDQGP----WYLAFYNDGKKMEQVFVLTTAIEIMDDCSTN-CNG 537 R+ S Q +E M++ P L G K + +CS N C Sbjct: 1271 RSQPTASAQ----LENMEEAPKRVSLALQLPEHGSK--------DIGNVPGNCSENPCQN 1318 Query: 538 NGECISG----HCHCFPGFLGPDC 557 G C+ G C C PGF G C Sbjct: 1319 GGTCVPGADAHSCDCGPGFKGRRC 1342 Score = 33.1 bits (74), Expect = 3.9 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 5/42 (11%) Query: 527 IMDDC-STNCNGNGECISGH----CHCFPGFLGPDCARDSCP 563 + D C S+ C G G C++ + C C G+ G DCA++ P Sbjct: 867 VSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908 Score = 32.3 bits (72), Expect = 6.6 Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 4/33 (12%) Query: 595 CIDPTCFGHGTCIMGV----CICVPGYKGEICE 623 C + C GTC+ G C C PG+KG CE Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343 >gi|93102379 low density lipoprotein-related protein 1B precursor [Homo sapiens] Length = 4599 Score = 114 bits (285), Expect = 1e-24 Identities = 81/266 (30%), Positives = 106/266 (39%), Gaps = 43/266 (16%) Query: 557 CARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEEQCIDP----TCFGHGTCIMGV-- 610 C +C LC N CVC G ++ +D TC G CI+ Sbjct: 4176 CLDLACEFLCLLNPS--GATCVCPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEKG 4233 Query: 611 ---CICVPGYKGEICEEEDCLDPMCSNHGICV-----KGECHCSTGWGGVNCETPLPVCQ 662 C C P Y GE CE C + C N G CV + C C+ G+ G NC VC+ Sbjct: 4234 DLRCHCWPSYSGERCEVNHCSN-YCQNGGTCVPSVLGRPTCSCALGFTGPNCGKT--VCE 4290 Query: 663 EQCSGHGTFLLDAG---VCSCDPKWTGSDCSTELCTMECGSHGVCSRGI-----CQCEEG 714 + C GT ++ AG C C P++TG C +C C + C+ G C C Sbjct: 4291 DFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTR 4350 Query: 715 WVGPTCEERSC----HSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 770 + GP CE C HC + +D C C+ G C + C G C+ Sbjct: 4351 YEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIASSCQL----------CDGYCYN 4400 Query: 771 NGRCTLDQ--NGWHCVCQVGWSGTGC 794 G C LD N C+C WSGT C Sbjct: 4401 GGTCQLDPETNVPVCLCSTNWSGTQC 4426 Score = 88.2 bits (217), Expect = 1e-16 Identities = 65/232 (28%), Positives = 85/232 (36%), Gaps = 36/232 (15%) Query: 529 DDCSTNCNGNGECISGH-----CHCFPGFLGPDCARDSCPVLCGGNGE-----YEKGHCV 578 D C C G CI CHC+P + G C + C C G + C Sbjct: 4215 DSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNHCSNYCQNGGTCVPSVLGRPTCS 4274 Query: 579 CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGV-----CICVPGYKGEICEEEDCLDPMCS 633 C G+ GP C + + C GTCI+ C C P Y G+ C+ C C Sbjct: 4275 CALGFTGPNCG---KTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVC-HHYCV 4330 Query: 634 NHGICVKG-----ECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAG--VCSCDPKWTG 686 N C G EC C T + G CE + C GH D+ C+C Sbjct: 4331 NSESCTIGDDGSVECVCPTRYEGPKCE--VDKCVRCHGGHCIINKDSEDIFCNCTNGKIA 4388 Query: 687 SDCSTELCTMECGSHGVCSRG------ICQCEEGWVGPTCEERSCHSHCTEH 732 S C +LC C + G C +C C W G CE + S ++H Sbjct: 4389 SSC--QLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCERPAPKSSKSDH 4438 Score = 73.9 bits (180), Expect = 2e-12 Identities = 54/202 (26%), Positives = 75/202 (37%), Gaps = 33/202 (16%) Query: 661 CQEQCSGHGTFLLDAGV---CSCDPKWTGSDCSTELCTMECGSHGVC-----SRGICQCE 712 C+ C G +L+ C C P ++G C C+ C + G C R C C Sbjct: 4217 CKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNHCSNYCQNGGTCVPSVLGRPTCSCA 4276 Query: 713 EGWVGPTCEERSCHSHCTEHGQC-----KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGL 767 G+ GP C + C C G C C C P + GD C +Y+ C Sbjct: 4277 LGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRC--QYYV------CHHY 4328 Query: 768 CFGNGRCTL-DQNGWHCVCQVGWSGTGCNVVMEMLCGD-----NLDNDGDGLTDCVD--- 818 C + CT+ D CVC + G C V + C N D++ D +C + Sbjct: 4329 CVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSE-DIFCNCTNGKI 4387 Query: 819 PDCCQ--QSNCYISPLCQGSPD 838 CQ CY CQ P+ Sbjct: 4388 ASSCQLCDGYCYNGGTCQLDPE 4409 Score = 71.2 bits (173), Expect = 1e-11 Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 29/184 (15%) Query: 528 MDDCSTNCNGNGECISG-----HCHCFPGFLGPDCARDSCPVLCGGNGEY-----EKGHC 577 ++ CS C G C+ C C GF GP+C + C C G + +C Sbjct: 4250 VNHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYC 4309 Query: 578 VCRHGWKGPECD--VPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNH 635 C+ + G C V C++ G C+C Y+G CE + C+ + Sbjct: 4310 HCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCVR---CHG 4366 Query: 636 GICVKGE------CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLD----AGVCSCDPKWT 685 G C+ + C+C+ G +C+ +C C GT LD VC C W+ Sbjct: 4367 GHCIINKDSEDIFCNCTNGKIASSCQ----LCDGYCYNGGTCQLDPETNVPVCLCSTNWS 4422 Query: 686 GSDC 689 G+ C Sbjct: 4423 GTQC 4426 Score = 39.7 bits (91), Expect = 0.041 Identities = 65/259 (25%), Positives = 92/259 (35%), Gaps = 63/259 (24%) Query: 535 CNGNGECI------SGHCHCFPGFLGPDCARDSCPVLCGGNGEYEK----GHCVCRHGW- 583 C N +CI +G C DC +SC + +Y + HC+ + W Sbjct: 3403 CTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSC------SPDYFQCKTTKHCISKL-WV 3455 Query: 584 --KGPEC-DVPEE-QCIDPTCFGHG-TCIMGVCI-----------CVPGYKGEICEEEDC 627 + P+C D +E C TC H C CI C E C+ + C Sbjct: 3456 CDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTC 3515 Query: 628 L--DPMCSNHGICVK------GECHCSTGWGGVNCETPLPVCQEQCS------------G 667 D +C+N G CV G+ C+ G NCET Q +CS G Sbjct: 3516 TLKDFLCAN-GDCVSSRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDG 3574 Query: 668 HGTFLLDAGVCSCDPKWTGSDCSTELCTME-CGSHGVCSRGICQCEEGWVGPTCEERSCH 726 H SC+P +C + C S + G C +G +E C Sbjct: 3575 HEDCKYGEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADG-----SDEMDCV 3629 Query: 727 SHCTE-HGQCKDGKCECSP 744 + C E +CK+ K C P Sbjct: 3630 TECKEDQFRCKN-KAHCIP 3647 Score = 39.7 bits (91), Expect = 0.041 Identities = 60/251 (23%), Positives = 79/251 (31%), Gaps = 60/251 (23%) Query: 538 NGECISGHCHCFPGFLGPDCARDS----CPVLCG------GNGEYEK------GHCVCRH 581 NG+C+S C F DCA S C C NG+ GH C++ Sbjct: 3524 NGDCVSSRFWCDGDF---DCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKY 3580 Query: 582 GWK-------GPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPM-CS 633 G P C E C C G C G C E D C Sbjct: 3581 GEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCK 3640 Query: 634 NHGICVK------GECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCS-----CDP 682 N C+ G C G NCE +C+ FL + +C CD Sbjct: 3641 NKAHCIPIRWLCDGIHDCVDGSDEENCERGGNICRAD-----EFLCNNSLCKLHFWVCDG 3695 Query: 683 KWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSH--CTEHGQCKDGKC 740 + D S E M C + +C P+ C ++ C + Q +G Sbjct: 3696 EDDCGDNSDEAPDM-------CVKFLC--------PSTRPHRCRNNRICLQSEQMCNGID 3740 Query: 741 ECSPGWEGDHC 751 EC + DHC Sbjct: 3741 ECGDNSDEDHC 3751 Score = 38.9 bits (89), Expect = 0.070 Identities = 72/327 (22%), Positives = 106/327 (32%), Gaps = 65/327 (19%) Query: 557 CARDSCPVLCGG---------NGEYEKGHCVCRHGWKGPECDVPEEQCI--DPTC----- 600 C C +L GG NG +C CR G + + +C+ + +C Sbjct: 2463 CELSPCALLNGGCHDLCLLTPNGRV---NCSCR----GDRILLEDNRCVTKNSSCNAYSE 2515 Query: 601 --FGHGTCIMGVCIC--VPGYKGE------ICEEEDC-------LDPMCSNHGICVKGEC 643 G+G CI C +P K + CE C + C HG GE Sbjct: 2516 FECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGEN 2575 Query: 644 HCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCS----CDPKWTGSDCSTELCTMECG 699 C ++C+ E GT + + C+ C +C+ CT Sbjct: 2576 DCGDNSDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCT-HFY 2634 Query: 700 SHGVCSRGICQCEEG--WVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYL 757 GV + G +C V PT C C D E + H +Y Sbjct: 2635 KLGVKTTGFIRCNSTSLCVLPTWI-------CDGSNDCGDYSDELKCPVQNKHKCEENYF 2687 Query: 758 DAVRDGC---PGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN----VVMEMLCGDNLDNDG 810 C +C G C ++ +HC W+ C+ + +C D D+ G Sbjct: 2688 SCPSGRCILNTWICDGQKDCEDGRDEFHCDSSCSWNQFACSAQKCISKHWIC-DGEDDCG 2746 Query: 811 DGLTDCVDPDCCQQSNCYISPL-CQGS 836 DGL + C C CQGS Sbjct: 2747 DGLDE--SDSICGAITCAADMFSCQGS 2771 Score = 37.4 bits (85), Expect = 0.20 Identities = 59/251 (23%), Positives = 81/251 (32%), Gaps = 55/251 (21%) Query: 565 LCGGNGEYEKG----HCVCRHGWKGPECDVPEEQCIDP--TCFGHGTC---------IMG 609 +C G + E G HC W C ++CI C G C I G Sbjct: 2700 ICDGQKDCEDGRDEFHCDSSCSWNQFACSA--QKCISKHWICDGEDDCGDGLDESDSICG 2757 Query: 610 VCICVPGYKGEICEEEDCLDP---MCSNHGICVKGECHCSTGWGGVN--CETPLPVCQEQ 664 C C+ P +C C G ST N C+ +C + Sbjct: 2758 AITCAADMFS--CQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNK 2815 Query: 665 CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGV-CSRGIC------QCE----- 712 F+ D D GSD S + +CG+ C+ G C QC+ Sbjct: 2816 VCIPKQFVCDHD----DDCGDGSDESPQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDC 2871 Query: 713 -----EGWVGPTCE--ERSCHS--------HCTEHGQCKDGKCECSPGWEGDHCTIAHYL 757 E + P C+ E+SC+S C G D K +C G + +C I L Sbjct: 2872 PDHSDEAPLNPKCKSAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERNCHINECL 2931 Query: 758 DAVRDGCPGLC 768 GC C Sbjct: 2932 SKKVSGCSQDC 2942 >gi|33598931 scavenger receptor class F, member 1 isoform 3 precursor [Homo sapiens] Length = 569 Score = 113 bits (283), Expect = 2e-24 Identities = 91/330 (27%), Positives = 120/330 (36%), Gaps = 51/330 (15%) Query: 535 CNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPE 592 C +G C +G CHC PG+ C R E G CVC+ GW G C Sbjct: 135 CGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF-- 192 Query: 593 EQCIDPTCFGHGTCI---MGVCICVPGYKGEICEEE-DCLDPMCSNHGICVKGECHCSTG 648 C HG+ G C C PG+ G C+++ +C+ CS GEC C G Sbjct: 193 ------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTCPPG 242 Query: 649 WGGVNCETPLPVCQE---------QCSGHGTFLLDAGVC-SCDPKWTGSDCSTELCTMEC 698 + G CE P P +C + D G C SC+P W G+ C Sbjct: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ------- 295 Query: 699 GSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCE-CSPGWEGDHCTIAHYL 757 C G G +CE++ H E + G C+ C PGW G C Sbjct: 296 -----------PCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT 344 Query: 758 DAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEM-LCGDNLD---NDGDGL 813 + C C + + D CVC G+ G CN G+N +GL Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL 404 Query: 814 TDCVDPDCCQQSNCYISPLCQGSPDPLDLI 843 V C S + L GS PL L+ Sbjct: 405 CHPVSGSCQPGSGSRDTALIAGSLVPLLLL 434 Score = 90.1 bits (222), Expect = 3e-17 Identities = 61/210 (29%), Positives = 83/210 (39%), Gaps = 41/210 (19%) Query: 613 CVPGYKGEICEEEDCLDPMCSNHGICVKGE-------CHCSTGWGGVNCETPL------P 659 C G++ + +++C P+C C K E C C G+ G +C + P Sbjct: 41 CCAGWRQK---DQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP 97 Query: 660 VCQEQ--CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC--SRGICQCEEGW 715 C+E C HG G C C G+ C CG HG C + G+C CE GW Sbjct: 98 DCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA---CGPHGRCDPATGVCHCEPGW 154 Query: 716 VGPTCEERSCHSHCTEHGQCKD--GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR 773 TC R C + T +C+ G C C PGW G C+ R C G Sbjct: 155 WSSTC-RRPCQCN-TAAARCEQATGACVCKPGWWGRRCSF-------RCNCHG------- 198 Query: 774 CTLDQNGWHCVCQVGWSGTGCNVVMEMLCG 803 +Q+ C C+ GW G C E + G Sbjct: 199 SPCEQDSGRCACRPGWWGPECQQQCECVRG 228 Score = 35.0 bits (79), Expect = 1.0 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 529 DDCSTNC----NGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHG 582 +DC + C G+ + ++G C C G+ GP C SCP G +G C C G Sbjct: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSC-NASCP--AGFHGNNCSVPCECPEG 403 >gi|33598929 scavenger receptor class F, member 1 isoform 1 precursor [Homo sapiens] Length = 830 Score = 113 bits (283), Expect = 2e-24 Identities = 91/330 (27%), Positives = 120/330 (36%), Gaps = 51/330 (15%) Query: 535 CNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPE 592 C +G C +G CHC PG+ C R E G CVC+ GW G C Sbjct: 135 CGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF-- 192 Query: 593 EQCIDPTCFGHGTCI---MGVCICVPGYKGEICEEE-DCLDPMCSNHGICVKGECHCSTG 648 C HG+ G C C PG+ G C+++ +C+ CS GEC C G Sbjct: 193 ------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTCPPG 242 Query: 649 WGGVNCETPLPVCQE---------QCSGHGTFLLDAGVC-SCDPKWTGSDCSTELCTMEC 698 + G CE P P +C + D G C SC+P W G+ C Sbjct: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ------- 295 Query: 699 GSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCE-CSPGWEGDHCTIAHYL 757 C G G +CE++ H E + G C+ C PGW G C Sbjct: 296 -----------PCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT 344 Query: 758 DAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEM-LCGDNLD---NDGDGL 813 + C C + + D CVC G+ G CN G+N +GL Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL 404 Query: 814 TDCVDPDCCQQSNCYISPLCQGSPDPLDLI 843 V C S + L GS PL L+ Sbjct: 405 CHPVSGSCQPGSGSRDTALIAGSLVPLLLL 434 Score = 90.1 bits (222), Expect = 3e-17 Identities = 61/210 (29%), Positives = 83/210 (39%), Gaps = 41/210 (19%) Query: 613 CVPGYKGEICEEEDCLDPMCSNHGICVKGE-------CHCSTGWGGVNCETPL------P 659 C G++ + +++C P+C C K E C C G+ G +C + P Sbjct: 41 CCAGWRQK---DQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP 97 Query: 660 VCQEQ--CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC--SRGICQCEEGW 715 C+E C HG G C C G+ C CG HG C + G+C CE GW Sbjct: 98 DCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA---CGPHGRCDPATGVCHCEPGW 154 Query: 716 VGPTCEERSCHSHCTEHGQCKD--GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGR 773 TC R C + T +C+ G C C PGW G C+ R C G Sbjct: 155 WSSTC-RRPCQCN-TAAARCEQATGACVCKPGWWGRRCSF-------RCNCHG------- 198 Query: 774 CTLDQNGWHCVCQVGWSGTGCNVVMEMLCG 803 +Q+ C C+ GW G C E + G Sbjct: 199 SPCEQDSGRCACRPGWWGPECQQQCECVRG 228 Score = 35.0 bits (79), Expect = 1.0 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 529 DDCSTNC----NGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHG 582 +DC + C G+ + ++G C C G+ GP C SCP G +G C C G Sbjct: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSC-NASCP--AGFHGNNCSVPCECPEG 403 >gi|110735443 delta-like 1 [Homo sapiens] Length = 723 Score = 113 bits (283), Expect = 2e-24 Identities = 88/287 (30%), Positives = 113/287 (39%), Gaps = 45/287 (15%) Query: 578 VCRHGWKGPECDV---PEEQCIDPTCFGHGTC-IMGVCICVPGYKGEICEEEDCLDPMCS 633 VC + G C V P + FGH TC G +C PG+KG C E CL Sbjct: 178 VCDEHYYGEGCSVFCRPRDDA-----FGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDE 232 Query: 634 NHGICVK-GECHCSTGWGGVNCETPL--PVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 690 HG C K GEC C GW G C+ + P C HGT C+C W G C+ Sbjct: 233 QHGFCDKPGECKCRVGWQGRYCDECIRYPGCL-----HGT-CQQPWQCNCQEGWGGLFCN 286 Query: 691 TELCTMECGSHGVCSRG-----------ICQCEEGWVGPTCE---ERSCHSHCTEHGQCK 736 +L C H C G C C G+ G TCE + S C G C Sbjct: 287 QDL--NYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCT 344 Query: 737 D----GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCT-LDQNGWHCVCQVGWSG 791 D C C PG+ G C ++ A G CF GRC+ G+ C C VG+SG Sbjct: 345 DLENSYSCTCPPGFYGKICELSAMTCA-----DGPCFNGGRCSDSPDGGYSCRCPVGYSG 399 Query: 792 TGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQGSPD 838 C ++ C + ++G D D C+ + C + D Sbjct: 400 FNCEKKID-YCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVD 445 Score = 110 bits (276), Expect = 1e-23 Identities = 95/336 (28%), Positives = 130/336 (38%), Gaps = 58/336 (17%) Query: 535 CNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEY--EKGHCVCRHGWKGPECDVPE 592 C GE + C PG+ GP C C C + + G C CR GW+G CD Sbjct: 204 CGERGEKV-----CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCD--- 255 Query: 593 EQCID-PTCFGHGTCIMG-VCICVPGYKGEICEEEDCLDPMCSNHGICVKGE-------- 642 +CI P C HGTC C C G+ G C ++ C++H C G Sbjct: 256 -ECIRYPGCL-HGTCQQPWQCNCQEGWGGLFCNQDL---NYCTHHKPCKNGATCTNTGQG 310 Query: 643 ---CHCSTGWGGVNCETPLPVCQEQ-CSGHG--TFLLDAGVCSCDPKWTGSDCSTELCTM 696 C C G+ G CE + C C G T L ++ C+C P + G C EL M Sbjct: 311 SYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKIC--ELSAM 368 Query: 697 ECGSHGVCSRG-----------ICQCEEGWVGPTCEERSCH---SHCTEHGQCKD----G 738 C G C G C+C G+ G CE++ + S C+ +C D Sbjct: 369 TCAD-GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY 427 Query: 739 KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVM 798 C C G+ G HC D V D C G C N + C C G++G C+ + Sbjct: 428 LCRCQAGFSGRHCD-----DNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPV 482 Query: 799 EMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPLCQ 834 C ++G + C+ + Y P CQ Sbjct: 483 SR-CEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517 Score = 65.1 bits (157), Expect = 9e-10 Identities = 46/147 (31%), Positives = 57/147 (38%), Gaps = 22/147 (14%) Query: 535 CNGNGECISG-----HCHCFPGFLGPDCAR--DSCPVLCGGNGEY-----EKGHCVCRHG 582 C G C C C G+ G +C + D C NG + C C+ G Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAG 434 Query: 583 WKGPECDVPEEQCIDPTCFGHGTCIMGV----CICVPGYKGEICEE--EDCLDPMCSNHG 636 + G CD + C C GTC GV C C PGY G C C C N Sbjct: 435 FSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGA 494 Query: 637 IC-VKGE---CHCSTGWGGVNCETPLP 659 C +G C C+ G+GG NC+ LP Sbjct: 495 TCHERGHRYVCECARGYGGPNCQFLLP 521 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 113,233,458 Number of Sequences: 37866 Number of extensions: 5792420 Number of successful extensions: 32400 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 146 Number of HSP's successfully gapped in prelim test: 472 Number of HSP's that attempted gapping in prelim test: 21986 Number of HSP's gapped (non-prelim): 4682 length of query: 2731 length of database: 18,247,518 effective HSP length: 120 effective length of query: 2611 effective length of database: 13,703,598 effective search space: 35780094378 effective search space used: 35780094378 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.