Guide to the Human Genome
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Search of human proteins with 122056623

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122056623 prion protein preproprotein [Homo sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122056628 prion protein preproprotein [Homo sapiens]               557   e-159
gi|122056625 prion protein preproprotein [Homo sapiens]               557   e-159
gi|122056623 prion protein preproprotein [Homo sapiens]               557   e-159
gi|34335270 prion protein preproprotein [Homo sapiens]                557   e-159
gi|4506113 prion protein preproprotein [Homo sapiens]                 557   e-159
gi|55956899 keratin 9 [Homo sapiens]                                   62   5e-10
gi|47132620 keratin 2 [Homo sapiens]                                   57   1e-08
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           57   2e-08
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]          57   2e-08
gi|109452587 family with sequence similarity 98, member B isofor...    54   1e-07
gi|56699482 hypothetical protein LOC25940 [Homo sapiens]               53   3e-07
gi|195972866 keratin 10 [Homo sapiens]                                 52   5e-07
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    52   5e-07
gi|119395750 keratin 1 [Homo sapiens]                                  51   1e-06
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 51   1e-06
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...    49   3e-06
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             49   4e-06
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    49   5e-06
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...    48   9e-06
gi|9966841 cell death regulator aven [Homo sapiens]                    48   9e-06
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             47   2e-05
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    46   3e-05
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              46   4e-05
gi|131412228 keratin 13 isoform b [Homo sapiens]                       46   4e-05
gi|131412225 keratin 13 isoform a [Homo sapiens]                       46   4e-05
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]            46   4e-05
gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a...    45   6e-05
gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b...    45   6e-05
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    45   8e-05
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...    45   8e-05

>gi|122056628 prion protein preproprotein [Homo sapiens]
          Length = 253

 Score =  557 bits (1435), Expect = e-159
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60
           MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
Sbjct: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60

Query: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120
           HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
Sbjct: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120

Query: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180
           VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
Sbjct: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180

Query: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240
           NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
Sbjct: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240

Query: 241 ILLISFLIFLIVG 253
           ILLISFLIFLIVG
Sbjct: 241 ILLISFLIFLIVG 253


>gi|122056625 prion protein preproprotein [Homo sapiens]
          Length = 253

 Score =  557 bits (1435), Expect = e-159
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60
           MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
Sbjct: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60

Query: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120
           HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
Sbjct: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120

Query: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180
           VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
Sbjct: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180

Query: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240
           NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
Sbjct: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240

Query: 241 ILLISFLIFLIVG 253
           ILLISFLIFLIVG
Sbjct: 241 ILLISFLIFLIVG 253


>gi|122056623 prion protein preproprotein [Homo sapiens]
          Length = 253

 Score =  557 bits (1435), Expect = e-159
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60
           MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
Sbjct: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60

Query: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120
           HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
Sbjct: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120

Query: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180
           VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
Sbjct: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180

Query: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240
           NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
Sbjct: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240

Query: 241 ILLISFLIFLIVG 253
           ILLISFLIFLIVG
Sbjct: 241 ILLISFLIFLIVG 253


>gi|34335270 prion protein preproprotein [Homo sapiens]
          Length = 253

 Score =  557 bits (1435), Expect = e-159
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60
           MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
Sbjct: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60

Query: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120
           HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
Sbjct: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120

Query: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180
           VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
Sbjct: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180

Query: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240
           NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
Sbjct: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240

Query: 241 ILLISFLIFLIVG 253
           ILLISFLIFLIVG
Sbjct: 241 ILLISFLIFLIVG 253


>gi|4506113 prion protein preproprotein [Homo sapiens]
          Length = 253

 Score =  557 bits (1435), Expect = e-159
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60
           MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
Sbjct: 1   MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP 60

Query: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120
           HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
Sbjct: 61  HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA 120

Query: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180
           VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
Sbjct: 121 VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV 180

Query: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240
           NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
Sbjct: 181 NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV 240

Query: 241 ILLISFLIFLIVG 253
           ILLISFLIFLIVG
Sbjct: 241 ILLISFLIFLIVG 253


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 40/105 (38%), Positives = 49/105 (46%), Gaps = 6/105 (5%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGG----GGWGQPHGGGWGQPHGGGWGQPHGGGWGQP 84
           GG  +GG    G GS GG+     GG    GG G  +GGG G  H GG G  H GG G  
Sbjct: 498 GGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGN 557

Query: 85  HGGGWGQGGGTHSQW--NKPSKPKTNMKHMAGAAAAGAVVGGLGG 127
           +GGG G GGG+   +     S+  +   H  G+   G   G  GG
Sbjct: 558 YGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGG 602



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 40/108 (37%), Positives = 49/108 (45%), Gaps = 18/108 (16%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQ------PHGGGWGQP--HGGG 80
           GG    G  Y G+GS GG+     GGGG G  +GGG G        +GGG G     GGG
Sbjct: 476 GGRGGSGGSY-GRGSRGGSG-GSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGG 533

Query: 81  WGQPHGGGW-GQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGG 127
           +G   GGG  G  GG HS         +   +  G+ + G   GG GG
Sbjct: 534 YGGGSGGGHSGGSGGGHS-------GGSGGNYGGGSGSGGGSGGGYGG 574



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 29/66 (43%), Positives = 33/66 (50%), Gaps = 8/66 (12%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG   GGSR  G G   G  Y   GG       GGG+G   GGG+G  +G G+G   G G
Sbjct: 87  GGGFGGGSR--GFGGASGGGYSSSGG------FGGGFGGGSGGGFGGGYGSGFGGFGGFG 138

Query: 89  WGQGGG 94
            G GGG
Sbjct: 139 GGAGGG 144



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQG-GGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGG 87
           GG ++GGS     G  GGN     G GGG G  +GGG G   G G     G G+G   GG
Sbjct: 539 GGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGG 598

Query: 88  GWGQG 92
            +G G
Sbjct: 599 SYGGG 603



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/78 (39%), Positives = 34/78 (43%), Gaps = 13/78 (16%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGG------------GWGQPHGGGWGQPHGGGWGQP 76
           GG  + G  Y G GS GG      GGG            G G    GG+G   GGG G  
Sbjct: 64  GGGGSFGYSYGG-GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGG 122

Query: 77  HGGGWGQPHGGGWGQGGG 94
            GGG+G   GG  G GGG
Sbjct: 123 FGGGYGSGFGGFGGFGGG 140



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 12/75 (16%)

Query: 29  GGWNTGGS--RY-PGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGG--GWGQPHGGGWG- 82
           GG ++GGS   Y  G GS GG+     GG G G    GG G  HGG  G+G   GG +G 
Sbjct: 547 GGGHSGGSGGNYGGGSGSGGGS----GGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGG 602

Query: 83  --QPHGGGWGQGGGT 95
             +  G G G GGG+
Sbjct: 603 GEEASGSGGGYGGGS 617



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 29/78 (37%), Positives = 36/78 (46%), Gaps = 12/78 (15%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGGGGWG---QPHGGGWGQ-------PHGGGWGQP--H 77
           G+  G SR  G+G  G   Y   GG G G      GGG+G          GGG+      
Sbjct: 52  GYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGF 111

Query: 78  GGGWGQPHGGGWGQGGGT 95
           GGG+G   GGG+G G G+
Sbjct: 112 GGGFGGGSGGGFGGGYGS 129



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 23/98 (23%)

Query: 31  WNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGW-GQPHGGGWGQPHGGGW 89
           + + G+   G G  GG+      GG +G+   GG G  +GGG  G  +GGG G   G G 
Sbjct: 465 FESSGAGKIGLGGRGGS------GGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518

Query: 90  GQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGG 127
             GGG+ S                G  + G   GG GG
Sbjct: 519 SYGGGSGS----------------GGGSGGGYGGGSGG 540



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 19/121 (15%)

Query: 27  KPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWG------QPHGGG----WGQPHGGGWGQP 76
           + GG   GG    G      +R+   GGGG G        +GGG     G+  GG +G  
Sbjct: 13  RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS 72

Query: 77  HGGGWGQPHGG------GWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYML 130
           +GGG G   GG      G G GGG+           ++     G    G+  G  GGY  
Sbjct: 73  YGGGSG---GGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGS 129

Query: 131 G 131
           G
Sbjct: 130 G 130



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 25/69 (36%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG  +GG    G G   G+R    G  G G   GG  G  +GGG      GG     G G
Sbjct: 560 GGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG-----GYG 614

Query: 89  WGQGGGTHS 97
            G G  +HS
Sbjct: 615 GGSGKSSHS 623



 Score = 32.7 bits (73), Expect = 0.31
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 9/84 (10%)

Query: 45  GGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQ-PHGGGWGQGGGTHSQWNKPS 103
           G   +   G G  G    GG G  +G G     GG +G    GGG+G G G        S
Sbjct: 461 GQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSG--------S 512

Query: 104 KPKTNMKHMAGAAAAGAVVGGLGG 127
           +  +   +  G+ + G   GG GG
Sbjct: 513 RGGSGGSYGGGSGSGGGSGGGYGG 536


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 5/109 (4%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGG--WGQPHG 86
           GG+++G S Y   G   G+R    G GG G   GGG+G   G G     GGG   G   G
Sbjct: 530 GGYSSGSSSYGSGGRQSGSR---GGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISG 586

Query: 87  GGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMS 135
           GG+G GGG HS         ++           + V G  G   GS+++
Sbjct: 587 GGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVT 635



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 19/104 (18%)

Query: 53  GGGGWGQPHGGGW--GQPHGGGWGQPHG-----GGWGQPHGGGWGQGGGTHSQWNKPSKP 105
           G GG G   GGG+  G    G  G+  G     GG G   GGG+G GGG+  ++      
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGS 579

Query: 106 KTNM-----------KHMAGAAAAGAVVGGLGGYMLGSAMSRPI 138
           K              KH +G  + G    G GGY  G   S  +
Sbjct: 580 KGGSISGGGYGSGGGKHSSGGGSRGGSSSG-GGYGSGGGGSSSV 622



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 27/60 (45%), Positives = 30/60 (50%), Gaps = 5/60 (8%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHG-GGWGQPHGGGWGQPHGG 87
           GG+  G S   G G  GG      GGGG+G    GG+G P G GG G P G G G   GG
Sbjct: 94  GGFGGGSSFGGGSGFSGGGF----GGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGG 149



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 33/101 (32%), Positives = 35/101 (34%), Gaps = 19/101 (18%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHG-- 86
           GG   G     G G          GGGG     GG  G+  G G G   GGG G   G  
Sbjct: 54  GGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGF 113

Query: 87  GGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGG 127
           GG G GGG    +  P                   VGGLGG
Sbjct: 114 GGGGFGGGRFGGFGGPGG-----------------VGGLGG 137



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 14/72 (19%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHG-- 86
           GG+   G  + G+G   G      GG G+    GGG+G   GGG+G    GG+G P G  
Sbjct: 81  GGFGAAGG-FGGRGGGFGGGSSFGGGSGFS---GGGFG---GGGFGGGRFGGFGGPGGVG 133

Query: 87  -----GGWGQGG 93
                GG+G GG
Sbjct: 134 GLGGPGGFGPGG 145



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 38/126 (30%), Positives = 46/126 (36%), Gaps = 24/126 (19%)

Query: 22  CKKRPKPGGWNTGGSRYPGQGSP---GGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPH- 77
           CK R + GG   GG R    GS    GG+R          + HGGG G   GGG+G    
Sbjct: 7   CKSRGRGGGG--GGFRGFSSGSAVVSGGSRRSTSSFSCLSR-HGGGGGGFGGGGFGSRSL 63

Query: 78  ----------------GGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAV 121
                           GGG+G   GG  G+GGG     +       +     G    G  
Sbjct: 64  VGLGGTKSISISVAGGGGGFGAA-GGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGR 122

Query: 122 VGGLGG 127
            GG GG
Sbjct: 123 FGGFGG 128


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 29/66 (43%), Positives = 35/66 (53%), Gaps = 1/66 (1%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG  + G  Y G  S GG     + GGG+G   GGG+G   GGG+G   GGG+G   GG 
Sbjct: 425 GGDRSSGGGYSGDRS-GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGY 483

Query: 89  WGQGGG 94
            G  GG
Sbjct: 484 GGDRGG 489



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 30/67 (44%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPHGG 87
           GG  +GG  Y G  S GG     + GGG+G    GGG+G   GGG+G   GGG+G   GG
Sbjct: 416 GGDRSGGG-YGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 474

Query: 88  GWGQGGG 94
           G+G   G
Sbjct: 475 GYGGDRG 481



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 32/72 (44%), Positives = 38/72 (52%), Gaps = 6/72 (8%)

Query: 29  GGWNTGGSR--YPGQGSPGGNRYPPQGGGGW-GQPHGGGWGQPH-GGGWGQPHGGGWGQP 84
           G    GG R  Y G  S GG       GGG+ G   GGG+G    GGG+G   GGG+G  
Sbjct: 404 GRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGD 463

Query: 85  HGGGWG--QGGG 94
            GGG+G  +GGG
Sbjct: 464 RGGGYGGDRGGG 475



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPH-GGGWGQPHGGGWGQPHGG 87
           GG+      Y G  S GG      GG G+G    GG+G    GGG+G   GGG+G   GG
Sbjct: 510 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 569

Query: 88  GWGQGGGTHSQWN 100
             G+ GG +   N
Sbjct: 570 YGGKMGGRNDYRN 582



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG  +GG    G G   G  Y    GGG+G   GGG+G    GG+G   GGG+G   GG 
Sbjct: 444 GGDRSGG----GYGGDRGGGYGGDRGGGYGGDRGGGYGGDR-GGYGGDRGGGYGGDRGGY 498

Query: 89  WGQGGG 94
            G  GG
Sbjct: 499 GGDRGG 504



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 37/83 (44%), Positives = 46/83 (55%), Gaps = 13/83 (15%)

Query: 25  RPKPG---GWNTGGSR-YPGQGSPGGNRYPPQG---GGGWG--QPHGGGW-GQPHGGGWG 74
           RP  G   G   GG R Y G+G  GG+R    G   GGG+G  +  GGG+ G   GGG+G
Sbjct: 385 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 444

Query: 75  QPH-GGGWGQPHGGGWG--QGGG 94
               GGG+G   GGG+G  +GGG
Sbjct: 445 GDRSGGGYGGDRGGGYGGDRGGG 467



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGG------GWGQ 83
           G   GG R  G G   G  Y    GGG+G   GG +G   GGG+G   GG      G+G 
Sbjct: 449 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGG-YGGDRGGGYGGDRGGYGGDRGGYGG 507

Query: 84  PHGGGWGQGGG 94
             GG  G  GG
Sbjct: 508 DRGGYGGDRGG 518



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGG--GGWGQPHGG------GWGQPHGGGWGQPHGGGW 81
           G + GG     +G  GG+R    GG  GG+G   GG      G+G   GG  G    GG+
Sbjct: 469 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 528

Query: 82  GQPHGGGWGQGG 93
           G   GGG G GG
Sbjct: 529 GGDRGGGSGYGG 540



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 29/75 (38%), Positives = 36/75 (48%), Gaps = 8/75 (10%)

Query: 26  PKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPH--GGGW-G 82
           P+P      G  + G+G  G   Y  +G GG G   GG  G   GGG+G     GGG+ G
Sbjct: 379 PRPEDSRPSGGDFRGRGYGGERGY--RGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSG 436

Query: 83  QPHGGGWG---QGGG 94
              GGG+G    GGG
Sbjct: 437 DRSGGGYGGDRSGGG 451



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 8/74 (10%)

Query: 29  GGWNTGGSRYPG-QGSPGGNR--YPPQGGGGWGQPHGGGWGQPHGGG--WGQPHGGGW-G 82
           GG+      Y G +G  GG+R  Y    GG  G    GG+G   GGG  +G    GG+ G
Sbjct: 489 GGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGG 548

Query: 83  QPHGGGWG--QGGG 94
              GGG+G  +GGG
Sbjct: 549 DRSGGGYGGDRGGG 562



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 14/77 (18%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGG-----GGWGQPHGGGWGQPHG-GGWGQPHGG--G 80
           GG+  GG R  G G   G     +GG     GG+G   GG +G     GG+G   GG  G
Sbjct: 481 GGY--GGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG-YGGDRSRGGYGGDRGGGSG 537

Query: 81  WGQPHGGGWG---QGGG 94
           +G    GG+G    GGG
Sbjct: 538 YGGDRSGGYGGDRSGGG 554



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 2/78 (2%)

Query: 53  GGGGWGQPHGGGWGQPHG--GGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMK 110
           GG G G+   GG+    G  G  G P  G W  P+           +  N+ ++P+    
Sbjct: 325 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 384

Query: 111 HMAGAAAAGAVVGGLGGY 128
             +G    G   GG  GY
Sbjct: 385 RPSGGDFRGRGYGGERGY 402


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 29/66 (43%), Positives = 35/66 (53%), Gaps = 1/66 (1%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG  + G  Y G  S GG     + GGG+G   GGG+G   GGG+G   GGG+G   GG 
Sbjct: 428 GGDRSSGGGYSGDRS-GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGY 486

Query: 89  WGQGGG 94
            G  GG
Sbjct: 487 GGDRGG 492



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 30/67 (44%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPHGG 87
           GG  +GG  Y G  S GG     + GGG+G    GGG+G   GGG+G   GGG+G   GG
Sbjct: 419 GGDRSGGG-YGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 477

Query: 88  GWGQGGG 94
           G+G   G
Sbjct: 478 GYGGDRG 484



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 32/72 (44%), Positives = 38/72 (52%), Gaps = 6/72 (8%)

Query: 29  GGWNTGGSR--YPGQGSPGGNRYPPQGGGGW-GQPHGGGWGQPH-GGGWGQPHGGGWGQP 84
           G    GG R  Y G  S GG       GGG+ G   GGG+G    GGG+G   GGG+G  
Sbjct: 407 GRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGD 466

Query: 85  HGGGWG--QGGG 94
            GGG+G  +GGG
Sbjct: 467 RGGGYGGDRGGG 478



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPH-GGGWGQPHGGGWGQPHGG 87
           GG+      Y G  S GG      GG G+G    GG+G    GGG+G   GGG+G   GG
Sbjct: 513 GGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 572

Query: 88  GWGQGGGTHSQWN 100
             G+ GG +   N
Sbjct: 573 YGGKMGGRNDYRN 585



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG  +GG    G G   G  Y    GGG+G   GGG+G    GG+G   GGG+G   GG 
Sbjct: 447 GGDRSGG----GYGGDRGGGYGGDRGGGYGGDRGGGYGGDR-GGYGGDRGGGYGGDRGGY 501

Query: 89  WGQGGG 94
            G  GG
Sbjct: 502 GGDRGG 507



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 37/83 (44%), Positives = 46/83 (55%), Gaps = 13/83 (15%)

Query: 25  RPKPG---GWNTGGSR-YPGQGSPGGNRYPPQG---GGGWG--QPHGGGW-GQPHGGGWG 74
           RP  G   G   GG R Y G+G  GG+R    G   GGG+G  +  GGG+ G   GGG+G
Sbjct: 388 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447

Query: 75  QPH-GGGWGQPHGGGWG--QGGG 94
               GGG+G   GGG+G  +GGG
Sbjct: 448 GDRSGGGYGGDRGGGYGGDRGGG 470



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGG------GWGQ 83
           G   GG R  G G   G  Y    GGG+G   GG +G   GGG+G   GG      G+G 
Sbjct: 452 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGG-YGGDRGGGYGGDRGGYGGDRGGYGG 510

Query: 84  PHGGGWGQGGG 94
             GG  G  GG
Sbjct: 511 DRGGYGGDRGG 521



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGG--GGWGQPHG------GGWGQPHGGGWGQPHGGGW 81
           G + GG     +G  GG+R    GG  GG+G   G      GG+G   GG  G    GG+
Sbjct: 472 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 531

Query: 82  GQPHGGGWGQGG 93
           G   GGG G GG
Sbjct: 532 GGDRGGGSGYGG 543



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 29/75 (38%), Positives = 36/75 (48%), Gaps = 8/75 (10%)

Query: 26  PKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPH--GGGW-G 82
           P+P      G  + G+G  G   Y  +G GG G   GG  G   GGG+G     GGG+ G
Sbjct: 382 PRPEDSRPSGGDFRGRGYGGERGY--RGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSG 439

Query: 83  QPHGGGWG---QGGG 94
              GGG+G    GGG
Sbjct: 440 DRSGGGYGGDRSGGG 454



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 8/74 (10%)

Query: 29  GGWNTGGSRYPG-QGSPGGNR--YPPQGGGGWGQPHGGGWGQPHGGG--WGQPHGGGW-G 82
           GG+      Y G +G  GG+R  Y    GG  G    GG+G   GGG  +G    GG+ G
Sbjct: 492 GGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGG 551

Query: 83  QPHGGGWG--QGGG 94
              GGG+G  +GGG
Sbjct: 552 DRSGGGYGGDRGGG 565



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 14/77 (18%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGG-----GGWGQPHGGGWGQPHG-GGWGQPHGG--G 80
           GG+  GG R  G G   G     +GG     GG+G   GG +G     GG+G   GG  G
Sbjct: 484 GGY--GGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG-YGGDRSRGGYGGDRGGGSG 540

Query: 81  WGQPHGGGWG---QGGG 94
           +G    GG+G    GGG
Sbjct: 541 YGGDRSGGYGGDRSGGG 557



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 2/78 (2%)

Query: 53  GGGGWGQPHGGGWGQPHG--GGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMK 110
           GG G G+   GG+    G  G  G P  G W  P+           +  N+ ++P+    
Sbjct: 328 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 387

Query: 111 HMAGAAAAGAVVGGLGGY 128
             +G    G   GG  GY
Sbjct: 388 RPSGGDFRGRGYGGERGY 405


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/95 (37%), Positives = 38/95 (40%), Gaps = 6/95 (6%)

Query: 39  PGQGSPGGNRYPP-----QGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGG 93
           P +  P     PP     +GGGG G   GGG G   GGG G    GGWG   GGGWG GG
Sbjct: 312 PNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWG-GGGGGWGGGG 370

Query: 94  GTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGY 128
           G    W              G        GG GGY
Sbjct: 371 GGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGY 405



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 35/66 (53%), Positives = 36/66 (54%), Gaps = 20/66 (30%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GGW  GG    G G  GG      GGGG G+   GGWG   GGGWG   GGG G   GGG
Sbjct: 336 GGWGGGG----GGGGRGG------GGGGGGR---GGWGGG-GGGWG---GGGGG---GGG 375

Query: 89  WGQGGG 94
           WG GGG
Sbjct: 376 WGGGGG 381



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 14/81 (17%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHG----------GGWGQPHGGGWGQPHG 78
           GGW  GG  + G G  GG  +   GGGG G   G          GG G   G G+G P+G
Sbjct: 357 GGWGGGGGGWGGGGGGGGG-WGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYG 415

Query: 79  GGWGQPHGGGWGQGGGTHSQW 99
           GG G   GGG G GGG + ++
Sbjct: 416 GGGG---GGGGGGGGGGYRRY 433


>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 41/131 (31%), Positives = 54/131 (41%), Gaps = 19/131 (14%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQ---PHGGGWGQPHGGGWGQPHGGGW--GQP 84
           G   GG  +   G  GG+    QGGG  G+    HGG      GGG G  H GGW  G  
Sbjct: 337 GGGRGGYEHSSYGGRGGH---EQGGGRGGRGGYDHGG-----RGGGRGNKHQGGWTDGGS 388

Query: 85  HGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSD 144
            GGG  Q GG      +P        +  G ++ G   GG GG+   S+ +      G  
Sbjct: 389 GGGGGYQDGGYRDSGFQPG------GYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGY 442

Query: 145 YEDRYYRENMH 155
            +D  Y++  H
Sbjct: 443 QQDNRYQDGGH 453



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 30/72 (41%), Positives = 33/72 (45%), Gaps = 10/72 (13%)

Query: 29  GGWNTGGSRYPGQGSPGG-----NRYPPQGGGGWGQPHGGGWGQPHGGGWG--QPHGGGW 81
           GG+ T  S Y G G  GG     NRY  Q GG  G   GG  G+   GG G     GGGW
Sbjct: 424 GGFQTSSS-YTGSGYQGGGYQQDNRY--QDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGW 480

Query: 82  GQPHGGGWGQGG 93
           G      + QGG
Sbjct: 481 GGRGSQNYHQGG 492



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 38/135 (28%), Positives = 45/135 (33%), Gaps = 8/135 (5%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPH-GG 87
           GGW  GGS   G    GG R      GG+   H  G  Q  G G  Q      G  + GG
Sbjct: 381 GGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGG 440

Query: 88  GWG-----QGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLG--GYMLGSAMSRPIIH 140
           G+      Q GG H         +       G A  G   GG G   Y  G    +   H
Sbjct: 441 GYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQH 500

Query: 141 FGSDYEDRYYRENMH 155
            G  Y    + +  H
Sbjct: 501 GGYQYNHSGFGQGRH 515


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 41/105 (39%), Positives = 49/105 (46%), Gaps = 17/105 (16%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG   GG  + G G  GG+     GGG  G  HGGG G   GGG+G   GG  G    GG
Sbjct: 460 GGGGRGGGSFGG-GYGGGS----SGGGSSGGGHGGGHGGSSGGGYG---GGSSGGGSSGG 511

Query: 89  WGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSA 133
            G GGG+ S  +  S         +G    G+  GG GGY  GS+
Sbjct: 512 -GYGGGSSSGGHGGSS--------SGGYGGGSSGGGGGGYGGGSS 547



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 61/228 (26%), Positives = 88/228 (38%), Gaps = 43/228 (18%)

Query: 25  RPKPGGWNTGGSR--YPGQGSPGGNRY-----PPQGGGGWGQPHGG--------GWGQPH 69
           R   GG   GGS   Y G G  GG  +         GG +G   GG        G G   
Sbjct: 59  RGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFG 118

Query: 70  GGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYM 129
           GGG+G   GGG+G   GGG+G  GG  S   K +    N +  +      A+      Y 
Sbjct: 119 GGGFG---GGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEE--SNYE 173

Query: 130 LGSAMSRPIIHFGSDY--EDRYYRENMHRYPNQVYYRPMDEYSNQ-NNFVHDCVNITIKQ 186
           L   +       G+ +  E R Y +         YY+ +D+  NQ  N   D  NI ++ 
Sbjct: 174 LEGKIKEWYEKHGNSHQGEPRDYSK---------YYKTIDDLKNQILNLTTDNANILLQI 224

Query: 187 HTVTTTT-----KGEN------FTETDVKMMERVVEQMCITQYERESQ 223
                       K EN        E D+  + RV++++ +T+ + E Q
Sbjct: 225 DNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQ 272



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 31/80 (38%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGG- 87
           GG + GG  Y G  S GG+     GGG     HGG     +GGG     GGG+G    G 
Sbjct: 492 GGSSGGG--YGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG 549

Query: 88  ----GWGQGGGTHSQWNKPS 103
               G G GGG+ S  +K S
Sbjct: 550 GSSSGGGYGGGSSSGGHKSS 569



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 6/82 (7%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG ++GG  Y G  S GG+     GG G G   GGG G  +GGG     GGG     G G
Sbjct: 505 GGGSSGGG-YGGGSSSGGHGGSSSGGYGGGSSGGGGGG--YGGG---SSGGGSSSGGGYG 558

Query: 89  WGQGGGTHSQWNKPSKPKTNMK 110
            G   G H   +  S  +++ K
Sbjct: 559 GGSSSGGHKSSSSGSVGESSSK 580



 Score = 29.3 bits (64), Expect = 3.4
 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 3/61 (4%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQ-PHGGGWGQPHGGGWGQPHGG 87
           GG ++GG  Y G  S GG      G  G G   GGG+G     GG      G  G+    
Sbjct: 523 GGSSSGG--YGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580

Query: 88  G 88
           G
Sbjct: 581 G 581


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 31/70 (44%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 53  GGGGWGQPHGGGWGQPHGGG-WGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKH 111
           GGGG     GGG G   GGG  G P GGG G P GGG G GGG       P     ++ H
Sbjct: 139 GGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGH 198

Query: 112 MAGAAAAGAV 121
           ++  AAA A+
Sbjct: 199 LSHPAAAAAM 208



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 41/113 (36%), Positives = 48/113 (42%), Gaps = 15/113 (13%)

Query: 34  GGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHG--GGWGQPHGGGWGQ 91
           GG  + G G  GG   P  GGG  G P GGG G P GGG G   G  GG   PH      
Sbjct: 140 GGGAHDGPGGGGG---PGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSL 196

Query: 92  GGGTH----SQWNKPS-KPKTNM-----KHMAGAAAAGAVVGGLGGYMLGSAM 134
           G  +H    +  N PS  P   +      H A AAAA A  G +      +A+
Sbjct: 197 GHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAV 249



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 35/115 (30%), Positives = 37/115 (32%), Gaps = 27/115 (23%)

Query: 26  PKPGGWNTGGSRYPGQGSPGGNRYPPQGG--GGWGQPHG-----GGWGQPHGGG-----W 73
           P  GG   GG    G G PGG    P GG  GG   PH      G    P          
Sbjct: 153 PGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPS 212

Query: 74  GQPHGG--GWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLG 126
           G PH G       HG           Q             +A A+AA AVVG  G
Sbjct: 213 GLPHPGLVAAAAHHGAAAAAAAAAAGQ-------------VAAASAAAAVVGAAG 254


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGG- 87
           GG+ +GGS Y      GG  Y   GGGG G+   G  G  +G G G    GG G  HG  
Sbjct: 523 GGYGSGGSSY----GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSY 578

Query: 88  GWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLG 126
           G G   G +   +      ++    +G  ++G  +GG G
Sbjct: 579 GSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRG 617



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 34  GGSRYPGQGS--PGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQ 91
           GGSR  G G    GG+ Y   GGG +G   GGG G+   G  G  +G G G    GG G 
Sbjct: 515 GGSRGGGGGGYGSGGSSYG-SGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGG 573

Query: 92  GGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGG 124
           G G++   +     +       G ++ G   GG
Sbjct: 574 GHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGG 606



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 30/116 (25%)

Query: 32  NTGGSRYPGQGSPGGNRYPPQGGGGWGQ------PHGGGWGQPHGGGWGQPHGGGWGQPH 85
           +T  +   G GS GG      GGGG+G         GG +G   GGG G+   G  G  +
Sbjct: 506 STSHTTISGGGSRGG------GGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSY 559

Query: 86  GGGWGQ-----GGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSR 136
           G G G      GGG H  +   S             ++G   GG GG   GS+  R
Sbjct: 560 GSGGGSYGSGGGGGGHGSYGSGS-------------SSGGYRGGSGGGGGGSSGGR 602



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 32/103 (31%), Positives = 36/103 (34%), Gaps = 35/103 (33%)

Query: 45  GGNRYPPQGGGGWGQPHGGGWGQ----------------PHGGGWGQPHGGGWGQPHGGG 88
           GG R+   GGGG     GGG+G                   GGG G   GGG+G    GG
Sbjct: 42  GGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGG 101

Query: 89  WGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLG 131
            G GGG                   G    G   GG GG+  G
Sbjct: 102 GGFGGG-------------------GFGGGGIGGGGFGGFGSG 125



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 31/67 (46%), Positives = 34/67 (50%), Gaps = 9/67 (13%)

Query: 29  GGWNTG-GSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGG 87
           GG  +G G  Y G G  GG      GGGG+G   GGG G    GG+G   GG  G   GG
Sbjct: 84  GGRGSGFGGGYGGGGFGGGGF----GGGGFG---GGGIGGGGFGGFGSGGGGFGGGGFGG 136

Query: 88  GWGQGGG 94
           G G GGG
Sbjct: 137 G-GYGGG 142



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 30/61 (49%), Positives = 33/61 (54%), Gaps = 11/61 (18%)

Query: 34  GGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGG 93
           GG R  G G  GG      GGGG+G   GGG+G   GGG G   GGG+G    GG G GG
Sbjct: 83  GGGR--GSGFGGGYGGGGFGGGGFG---GGGFG---GGGIG---GGGFGGFGSGGGGFGG 131

Query: 94  G 94
           G
Sbjct: 132 G 132



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 26/61 (42%), Positives = 30/61 (49%), Gaps = 6/61 (9%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQ--PHG 86
           GG   GG  + G G  GG      GGGG+G    GG G   GG  G  +GGG+G   P G
Sbjct: 95  GGGGFGGGGFGGGGFGGGGI----GGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPG 150

Query: 87  G 87
           G
Sbjct: 151 G 151



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 26/61 (42%), Positives = 30/61 (49%), Gaps = 7/61 (11%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGW 89
           G   GG  + G G  GG      GGGG G   GGG+G    GG G   GG  G  +GGG+
Sbjct: 91  GGGYGGGGFGGGGFGGGGF----GGGGIG---GGGFGGFGSGGGGFGGGGFGGGGYGGGY 143

Query: 90  G 90
           G
Sbjct: 144 G 144



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 5/83 (6%)

Query: 31  WNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWG 90
           + +GG  Y   G  GG+     G  G G   GG  G   GGG G   G G G    GG  
Sbjct: 559 YGSGGGSYGSGGGGGGH-----GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSI 613

Query: 91  QGGGTHSQWNKPSKPKTNMKHMA 113
            G G+ S   K S   +++K ++
Sbjct: 614 GGRGSSSGGVKSSGGSSSVKFVS 636



 Score = 35.8 bits (81), Expect = 0.037
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 19/84 (22%)

Query: 29 GGWNTGGS---RYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQ---------- 75
          GG+++G +    Y  + +    R    GGG +    GGG     GGG+G           
Sbjct: 15 GGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSK 74

Query: 76 ------PHGGGWGQPHGGGWGQGG 93
                  GGG G   GGG+G GG
Sbjct: 75 SISISVARGGGRGSGFGGGYGGGG 98



 Score = 34.7 bits (78), Expect = 0.082
 Identities = 24/67 (35%), Positives = 26/67 (38%), Gaps = 5/67 (7%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG   G   Y    S GG R    GGGG     G   G+  GGG      GG G   GG 
Sbjct: 569 GGGGGGHGSYGSGSSSGGYRGGSGGGGG-----GSSGGRGSGGGSSGGSIGGRGSSSGGV 623

Query: 89  WGQGGGT 95
              GG +
Sbjct: 624 KSSGGSS 630


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 33/76 (43%), Positives = 36/76 (47%), Gaps = 8/76 (10%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQG-------GGGWGQPHGGGWGQPHGGGWGQPHGGGW 81
           G  + GG    GQGS GGN+    G       G G GQ  GGG G   G G G  HG G 
Sbjct: 526 GQGSRGGQGSNGQGS-GGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGG 584

Query: 82  GQPHGGGWGQGGGTHS 97
           G+  GGG G G G  S
Sbjct: 585 GKNSGGGKGSGSGKGS 600



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 30/69 (43%), Positives = 31/69 (44%), Gaps = 5/69 (7%)

Query: 40  GQGSPGGNRYPPQGGGG---WGQPHGGGWGQPHGGGW--GQPHGGGWGQPHGGGWGQGGG 94
           GQGS GG     QG GG        G   G   GGG   G  HG G GQ  G G G GGG
Sbjct: 526 GQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGG 585

Query: 95  THSQWNKPS 103
            +S   K S
Sbjct: 586 KNSGGGKGS 594



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 29/81 (35%), Positives = 32/81 (39%), Gaps = 17/81 (20%)

Query: 31  WNTGGSRYPGQG-----------SPGGNRYPPQGGGGW------GQPHGGGWGQPHGGGW 73
           W +G  R  G G           S GGN+   +G G        GQ  GG      G G 
Sbjct: 493 WGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGT 552

Query: 74  GQPHGGGWGQPHGGGWGQGGG 94
              HG G GQ  GGG G GGG
Sbjct: 553 AGGHGSGGGQRPGGGHGSGGG 573



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 8/78 (10%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           GG  +GG + PG G   G      GG G G  HG G G+  GGG G   G G G    G 
Sbjct: 554 GGHGSGGGQRPGGGHGSG------GGQGPGDGHGSGGGKNSGGGKGS--GSGKGSDGDGE 605

Query: 89  WGQGGGTHSQWNKPSKPK 106
            G+     S + K ++ K
Sbjct: 606 RGKSLKKRSYFGKLTQSK 623



 Score = 35.8 bits (81), Expect = 0.037
 Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 8/73 (10%)

Query: 33  TGGSRYPGQGSPGGNR--------YPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQP 84
           +G   +  +G+P G          Y P    G G   G G GQ   G     H  G  Q 
Sbjct: 463 SGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQC 522

Query: 85  HGGGWGQGGGTHS 97
            G G G  GG  S
Sbjct: 523 SGEGQGSRGGQGS 535



 Score = 28.9 bits (63), Expect = 4.5
 Identities = 23/89 (25%), Positives = 33/89 (37%), Gaps = 7/89 (7%)

Query: 37  RYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGG------GWGQPHGGGWG 90
           R+P +    G R   +  G  G  + G  G P G    +  GG       WG  +G G G
Sbjct: 444 RHPAEAPNNGARLSSEVSGS-GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSG 502

Query: 91  QGGGTHSQWNKPSKPKTNMKHMAGAAAAG 119
            G G++ Q +       N     G  + G
Sbjct: 503 GGQGSNGQGSSSHSSGGNQCSGEGQGSRG 531


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 7/110 (6%)

Query: 29  GGWNTGGSRYPGQGSPGGNR-----YPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQ 83
           G +  G   Y G G  GGN      Y  +GG G G P  G  G  +GGG G       G 
Sbjct: 258 GSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGN 317

Query: 84  PHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGL--GGYMLG 131
             GG +G GG  +   N   + ++N   M G +  G   G    GGY  G
Sbjct: 318 FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSG 367



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 30/67 (44%), Positives = 36/67 (53%), Gaps = 8/67 (11%)

Query: 29  GGWNTG-GSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHG-GGWGQPHGGGWGQPHG 86
           GG N G G  + G+G  GG      GGGG    +GGG G  +G GG G  +GGG G    
Sbjct: 233 GGGNFGRGGNFGGRGGYGG------GGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSR 286

Query: 87  GGWGQGG 93
           GG+G GG
Sbjct: 287 GGYGGGG 293



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 30/83 (36%), Positives = 36/83 (43%), Gaps = 21/83 (25%)

Query: 28  PGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGG---------------WGQPHGGG 72
           PG  N GG    G G  G N     GGG +G   GGG               +G   GG 
Sbjct: 294 PGYGNQGGGYGGGGGYDGYNEGGNFGGGNYG---GGGNYNDFGNYSGQQQSNYGPMKGGS 350

Query: 73  WGQPHGGGWGQPHGGGWGQGGGT 95
           +G   G   G P+GGG+G GGG+
Sbjct: 351 FG---GRSSGSPYGGGYGSGGGS 370



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 12/69 (17%)

Query: 30  GWNTGGSRYPGQGSPGGN-----RYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQP 84
           G+N GG+   G    GGN      Y  Q    +G   GG +G   G   G P+GGG+G  
Sbjct: 311 GYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFG---GRSSGSPYGGGYGS- 366

Query: 85  HGGGWGQGG 93
              G G GG
Sbjct: 367 ---GGGSGG 372



 Score = 35.8 bits (81), Expect = 0.037
 Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 13/63 (20%)

Query: 30  GWNTGGSRYPGQGSPG--GN-------RYPPQGGGGWGQPHGGGWGQPHGGGWGQPHG-G 79
           G N GG  Y G G+    GN        Y P  GG +G   G   G P+GGG+G   G G
Sbjct: 315 GGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFG---GRSSGSPYGGGYGSGGGSG 371

Query: 80  GWG 82
           G+G
Sbjct: 372 GYG 374



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 41/133 (30%), Positives = 48/133 (36%), Gaps = 23/133 (17%)

Query: 24  KRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQ--PHGGGWGQPHG-GG 80
           +R + GG      R    G  GGN       GG G   GGG G    +GGG G  +G GG
Sbjct: 213 QRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGG 272

Query: 81  WGQPHGGG------WGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAM 134
            G  +GGG       G GGG     N+            G    G   GG  GY  G   
Sbjct: 273 DGGNYGGGPGYSSRGGYGGGGPGYGNQ-----------GGGYGGG---GGYDGYNEGGNF 318

Query: 135 SRPIIHFGSDYED 147
                  G +Y D
Sbjct: 319 GGGNYGGGGNYND 331


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 31/88 (35%), Positives = 35/88 (39%), Gaps = 20/88 (22%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGW 89
           G  TG  R  G  SP      P GG GWG P                  GG GQ  G   
Sbjct: 286 GRKTGSQRSSGSRSPS-----PSGGSGWGSPQ---------------RNGGSGQRSGAHG 325

Query: 90  GQGGGTHSQWNKPSKPKTNMKHMAGAAA 117
           G+ G  HS  +KPS P   ++  A AAA
Sbjct: 326 GRPGSAHSPPDKPSSPSPRVRDKAAAAA 353


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 49/153 (32%), Positives = 59/153 (38%), Gaps = 22/153 (14%)

Query: 28  PGGWNTGGSRY-----PGQGSPGGNRYPPQGGGGWGQ-------PHGGGWGQPHGGGWGQ 75
           PGG   GG  +     PG G  GG+ + P  G G G        PH G  G   G G  +
Sbjct: 787 PGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHR 846

Query: 76  PH-GGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAM 134
           PH G G G PHG       G     ++   P  +  H       G   G  GG+  G  M
Sbjct: 847 PHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGDM 906

Query: 135 S-RPII-HFGSDYEDRYYRENMHRYPNQVYYRP 165
           S RP+  HF      RY  EN     N  +Y P
Sbjct: 907 SNRPVCRHFMMKGNCRY--EN-----NCAFYHP 932



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 21/91 (23%)

Query: 25  RPKPGGWNTGGSRYPGQGSPGG------NRYPPQG-GGGWG---QPHGGGWGQPHGGGWG 74
           R  PGG   GG  +     PGG         P +G GGG G   +PH G  G   GGG  
Sbjct: 738 RGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGH 797

Query: 75  QPH--------GGGWGQPH---GGGWGQGGG 94
           +PH        GG   +PH   GGG G GGG
Sbjct: 798 RPHEGPGGGISGGSGHRPHEGPGGGMGAGGG 828



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 44/126 (34%), Positives = 49/126 (38%), Gaps = 23/126 (18%)

Query: 30  GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPH---GGGWGQPHGGGWGQPHGGGWGQPH- 85
           G  +GG    G+G PGG       GGG  +PH   GGG G   G    +  GGG G  H 
Sbjct: 727 GGRSGGGPPNGRGGPGGGMV----GGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHR 782

Query: 86  -----GGGWGQGGGTHSQWNKP----SKPKTNMKHMAGAAAAGAVVG-----GLGGYMLG 131
                GG  G GGG H     P    S    +  H       GA  G     G GG M G
Sbjct: 783 PHEGPGGSMG-GGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGG 841

Query: 132 SAMSRP 137
           S   RP
Sbjct: 842 SGGHRP 847



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 44/140 (31%), Positives = 52/140 (37%), Gaps = 26/140 (18%)

Query: 20  GLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWG-----------QP 68
           GL    P   G+  GG   PG G  G   +PP  GG    PHGG  G            P
Sbjct: 618 GLLGPGPIANGFPPGG---PG-GPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPP 673

Query: 69  HGGG--WGQPHGGGWGQPHGGGWGQGGGTHSQ------WNKPSKPKTNMKHMAGAAAAGA 120
            GG   W  P     G P  GG G G G + +       N+P  P    +   G  + G 
Sbjct: 674 RGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGG 733

Query: 121 VV---GGLGGYMLGSAMSRP 137
                GG GG M+G    RP
Sbjct: 734 PPNGRGGPGGGMVGGGGHRP 753


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 1/99 (1%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
           G  N GG    G G  GG+R    GG G+G    G  G      +    GGG+G   G  
Sbjct: 246 GFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSN 305

Query: 89  WGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGG 127
           +G GGG+++ +   +   +N   M G    G   G  GG
Sbjct: 306 FG-GGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGG 343



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 27/74 (36%), Positives = 35/74 (47%), Gaps = 5/74 (6%)

Query: 24  KRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQ 83
           +R + G  N GG R  G G  G + +   G GG     GG  G   GGG+G    G  G 
Sbjct: 193 QRGRSGSGNFGGGR--GGGFGGNDNF---GRGGNFSGRGGFGGSRGGGGYGGSGDGYNGF 247

Query: 84  PHGGGWGQGGGTHS 97
            + GG+G GG  +S
Sbjct: 248 GNDGGYGGGGPGYS 261


>gi|9966841 cell death regulator aven [Homo sapiens]
          Length = 362

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 31/80 (38%), Positives = 37/80 (46%), Gaps = 17/80 (21%)

Query: 30 GWNTGGSRYPGQGSPGGNRYPPQ----------GGGGWGQPHGGGWGQPHGGGWGQPHGG 79
          G   G  R PG+G PGG+R+  +          GGGG G   GG  G+  G G+    GG
Sbjct: 6  GARGGRGRRPGRGRPGGDRHSERPGAAAAVARGGGGGGGGDGGGRRGRGRGRGFRGARGG 65

Query: 80 --GWGQPHG-----GGWGQG 92
            G G P G     GGWG G
Sbjct: 66 RGGGGAPRGSRREPGGWGAG 85



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 7/43 (16%)

Query: 29 GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHG-----GGWG 66
          GG + GG R  G+G   G R    G GG G P G     GGWG
Sbjct: 43 GGGDGGGRR--GRGRGRGFRGARGGRGGGGAPRGSRREPGGWG 83


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 26  PKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPH 85
           P P G+ T     P +  P      P+GG G G    GG G   GGG G P  G    P 
Sbjct: 350 PHPYGFPTAFGLCPKKDDPVLGAGEPKGGPGTGS---GGGGAGTGGGAGGP--GASHLPP 404

Query: 86  GGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAV 121
           G G G GGG     ++PS    +   +A AAAA  V
Sbjct: 405 GAGAGPGGGAMFWGHQPSGAAKDAAAVAAAAAAATV 440



 Score = 32.7 bits (73), Expect = 0.31
 Identities = 26/71 (36%), Positives = 28/71 (39%), Gaps = 27/71 (38%)

Query: 20  GLCKKRPKP-----------------GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHG 62
           GLC K+  P                 GG  TGG    G G PG +  PP  G G   P G
Sbjct: 360 GLCPKKDDPVLGAGEPKGGPGTGSGGGGAGTGG----GAGGPGASHLPPGAGAG---PGG 412

Query: 63  GG--WG-QPHG 70
           G   WG QP G
Sbjct: 413 GAMFWGHQPSG 423


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 38/116 (32%), Positives = 43/116 (37%), Gaps = 32/116 (27%)

Query: 29  GGWNTGGSR---------------YPGQGSPGGNRYPPQGGGGWGQPHGGG-WGQPHGG- 71
           GG   GG R               Y G G  GG  Y   GGGG G  +GG  +G   GG 
Sbjct: 196 GGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGF 255

Query: 72  GWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGG 127
           G    H   +G    GG G GGG  S W              G + +G   GG GG
Sbjct: 256 GSYSQHQSSYGPMKSGGGGGGGG--SSW-------------GGRSNSGPYRGGYGG 296



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 30/89 (33%), Positives = 36/89 (40%), Gaps = 27/89 (30%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGG------------------WGQPHG 70
           GG+N+    Y G G  GG  Y   GGGG G  +GG                   +G    
Sbjct: 215 GGYNS----YGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKS 270

Query: 71  GGWGQPHGGGWG-----QPHGGGWGQGGG 94
           GG G   G  WG      P+ GG+G GGG
Sbjct: 271 GGGGGGGGSSWGGRSNSGPYRGGYGGGGG 299



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 9/103 (8%)

Query: 30  GWNTGGSRYP-----GQGSPGGNRYP--PQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWG 82
           G   GGSR       G+G  GG       +GGGG    + GG+G   GGG+    GGG G
Sbjct: 182 GGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSY-GGYGGGGGGGYNAYGGGGGG 240

Query: 83  QPHGGG-WGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGG 124
             +GG  +G G G    +++       MK   G    G+  GG
Sbjct: 241 SSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGG 283



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 44  PGGNRYPPQGGGGWGQPHGGGWGQPHGGGW---GQPHGGGWGQPHGGGWGQGGG 94
           P  + Y   GGGG     GG  G+  GGG    G   GGG G    GG+G GGG
Sbjct: 175 PKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGG 228


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 29/95 (30%), Positives = 36/95 (37%), Gaps = 6/95 (6%)

Query: 53  GGGGWGQPHGGGWGQPHGGGWGQPHGGGW------GQPHGGGWGQGGGTHSQWNKPSKPK 106
           GGGG G   GGG G+  GG    P   GW       Q  GG  G+G       +   K  
Sbjct: 168 GGGGEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTP 227

Query: 107 TNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHF 141
                 +G+  AG   GG G Y     +   +I F
Sbjct: 228 GTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQF 262



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 35/116 (30%), Positives = 42/116 (36%), Gaps = 22/116 (18%)

Query: 26  PKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPH 85
           P P GW   G R   +G  GG    P        P     G+  G G  +  G G     
Sbjct: 191 PPPRGWRGKGVRAQQRGGSGGEGASP-------SPSSSSAGKTPGTG-SRNSGSGVA--- 239

Query: 86  GGGWGQGGGTHSQWNKPSKPKTNM-----KHMAGAAAAGAVVGGLGGYMLGSAMSR 136
           GGG G GG   S W +       +     K  A AAAA A +    G   G + SR
Sbjct: 240 GGGSGGGG---SYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNG---GGSSSR 289


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 27/63 (42%), Positives = 33/63 (52%), Gaps = 6/63 (9%)

Query: 30 GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGW 89
          G +T  +R+   GS GG       GGG     GGG G   GGG+G   GGG+G   GGG+
Sbjct: 28 GVSTCSTRFVSGGSAGGY------GGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGF 81

Query: 90 GQG 92
          G G
Sbjct: 82 GGG 84



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 26/66 (39%), Positives = 29/66 (43%)

Query: 29 GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
          GG   GGS   G G            GG    +GGG     GGG G   GGG+G   GGG
Sbjct: 13 GGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGG 72

Query: 89 WGQGGG 94
          +G G G
Sbjct: 73 YGGGLG 78


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 27/63 (42%), Positives = 33/63 (52%), Gaps = 6/63 (9%)

Query: 30 GWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGW 89
          G +T  +R+   GS GG       GGG     GGG G   GGG+G   GGG+G   GGG+
Sbjct: 28 GVSTCSTRFVSGGSAGGY------GGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGF 81

Query: 90 GQG 92
          G G
Sbjct: 82 GGG 84



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 26/66 (39%), Positives = 29/66 (43%)

Query: 29 GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGG 88
          GG   GGS   G G            GG    +GGG     GGG G   GGG+G   GGG
Sbjct: 13 GGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGG 72

Query: 89 WGQGGG 94
          +G G G
Sbjct: 73 YGGGLG 78


>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 29/82 (35%), Positives = 36/82 (43%), Gaps = 14/82 (17%)

Query: 26  PKPGGWNTGGSRYPGQG----SPGGNRYPPQGGGGWGQPHGGGW----------GQPHGG 71
           P   G   G    PG G    +PGG   PP GGG +G P+ G +          G   GG
Sbjct: 29  PPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGG 88

Query: 72  GWGQPHGGGWGQPHGGGWGQGG 93
            +GQP    +G    G +GQGG
Sbjct: 89  PYGQPPPSSYGAQQPGLYGQGG 110



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 28/64 (43%), Positives = 36/64 (56%), Gaps = 6/64 (9%)

Query: 35 GSRYPGQGSPGGNRYP--PQGGG--GWGQPHGGGWGQPHGGG-WGQPHGGG-WGQPHGGG 88
          G+     G+P G+ YP  P  GG  G G P GGG+G P  GG +G P GGG +G P+ G 
Sbjct: 12 GAAGQAPGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHPNPGM 71

Query: 89 WGQG 92
          +  G
Sbjct: 72 FPSG 75



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 31/74 (41%), Positives = 40/74 (54%), Gaps = 14/74 (18%)

Query: 35 GSRYPGQGSPGG---NRYPPQGGGGWGQP-HGGGWGQPHGGG-WGQPHGGGW-----GQP 84
          GS YPG  + GG   +  PP  GGG+G P  GG +G P GGG +G P+ G +     G P
Sbjct: 23 GSYYPGPPNSGGQYGSGLPP--GGGYGGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGP 80

Query: 85 HGGGWGQGGGTHSQ 98
          +GG     GG + Q
Sbjct: 81 YGG--AAPGGPYGQ 92



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 3/67 (4%)

Query: 28  PGGWNTGGSRYPGQ---GSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQP 84
           P G    G   PG    G+PGG       GG +GQP    +G    G +GQ        P
Sbjct: 58  PAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPPNVDP 117

Query: 85  HGGGWGQ 91
               W Q
Sbjct: 118 EAYSWFQ 124


>gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a
           [Homo sapiens]
          Length = 346

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 34  GGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHG-GGWGQPHGGG---W 89
           GGS   G G  G  R      GG+G     G G  + GG+G P G GG+G+  GG    +
Sbjct: 273 GGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYY 332

Query: 90  GQGGGTHSQW 99
           GQGG +   W
Sbjct: 333 GQGGMSGGGW 342



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 23/56 (41%), Positives = 29/56 (51%), Gaps = 12/56 (21%)

Query: 51  PQGGGGWGQPHGGGWGQP----HGG-------GWGQPHGGGWGQPHG-GGWGQGGG 94
           P GG G G    GG+G+      GG       G G  + GG+G P G GG+G+GGG
Sbjct: 271 PGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGG 326


>gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b
           [Homo sapiens]
          Length = 331

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 34  GGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHG-GGWGQPHGGG---W 89
           GGS   G G  G  R      GG+G     G G  + GG+G P G GG+G+  GG    +
Sbjct: 258 GGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYY 317

Query: 90  GQGGGTHSQW 99
           GQGG +   W
Sbjct: 318 GQGGMSGGGW 327



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 23/56 (41%), Positives = 29/56 (51%), Gaps = 12/56 (21%)

Query: 51  PQGGGGWGQPHGGGWGQP----HGG-------GWGQPHGGGWGQPHG-GGWGQGGG 94
           P GG G G    GG+G+      GG       G G  + GG+G P G GG+G+GGG
Sbjct: 256 PGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGG 311


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 32/79 (40%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 26  PKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGG--GWGQPHGG-GWGQPHGGGWG 82
           P PG    GGS   G G   G+ Y   GGG  G   GG  G+G   GG G G P  G  G
Sbjct: 221 PGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQG 280

Query: 83  QPHGGGW-GQGGGTHSQWN 100
             +GGG+   GGG +   N
Sbjct: 281 GGYGGGYDNYGGGNYGSGN 299



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 37/109 (33%), Positives = 47/109 (43%), Gaps = 20/109 (18%)

Query: 28  PGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGG 87
           PGG N GGS  PG G  GG     +GG G G P  G  G  +GGG+    GG +G    G
Sbjct: 251 PGGGNFGGS--PGYG--GG-----RGGYGGGGPGYGNQGGGYGGGYDNYGGGNYG---SG 298

Query: 88  GWGQGGGTHSQWNKPSKPKT----NMKHMAGAAAAG----AVVGGLGGY 128
            +   G  + Q +     K+      ++M G    G       GG GGY
Sbjct: 299 NYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGY 347



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 16/87 (18%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWG----QPHGGG------------ 72
           GG+  GG  Y  QG   G  Y   GGG +G  +   +G    QP   G            
Sbjct: 267 GGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRN 326

Query: 73  WGQPHGGGWGQPHGGGWGQGGGTHSQW 99
            G P+GGG   P G G   G G  S++
Sbjct: 327 MGGPYGGGNYGPGGSGGSGGYGGRSRY 353



 Score = 34.7 bits (78), Expect = 0.082
 Identities = 27/72 (37%), Positives = 32/72 (44%), Gaps = 11/72 (15%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQG----GGGWGQPHGGGWGQPHGGGWGQPHGGGWGQP 84
           G +  G SR       GGN  P  G    GG  G   G G+G  + G  G P GG +G  
Sbjct: 205 GNFGFGDSR-----GGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGS 259

Query: 85  --HGGGWGQGGG 94
             +GGG G  GG
Sbjct: 260 PGYGGGRGGYGG 271



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 1/62 (1%)

Query: 34  GGSRYPGQGSPGGNRYPPQGGGGW-GQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQG 92
           GG+   G    GG  + P  G  + G   G G G+  G G+    GG  G   GG  G G
Sbjct: 204 GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYG 263

Query: 93  GG 94
           GG
Sbjct: 264 GG 265


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 32/79 (40%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 26  PKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGG--GWGQPHGG-GWGQPHGGGWG 82
           P PG    GGS   G G   G+ Y   GGG  G   GG  G+G   GG G G P  G  G
Sbjct: 209 PGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQG 268

Query: 83  QPHGGGW-GQGGGTHSQWN 100
             +GGG+   GGG +   N
Sbjct: 269 GGYGGGYDNYGGGNYGSGN 287



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 37/109 (33%), Positives = 47/109 (43%), Gaps = 20/109 (18%)

Query: 28  PGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGG 87
           PGG N GGS  PG G  GG     +GG G G P  G  G  +GGG+    GG +G    G
Sbjct: 239 PGGGNFGGS--PGYG--GG-----RGGYGGGGPGYGNQGGGYGGGYDNYGGGNYG---SG 286

Query: 88  GWGQGGGTHSQWNKPSKPKT----NMKHMAGAAAAG----AVVGGLGGY 128
            +   G  + Q +     K+      ++M G    G       GG GGY
Sbjct: 287 NYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGY 335



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 16/87 (18%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWG----QPHGGG------------ 72
           GG+  GG  Y  QG   G  Y   GGG +G  +   +G    QP   G            
Sbjct: 255 GGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRN 314

Query: 73  WGQPHGGGWGQPHGGGWGQGGGTHSQW 99
            G P+GGG   P G G   G G  S++
Sbjct: 315 MGGPYGGGNYGPGGSGGSGGYGGRSRY 341



 Score = 34.7 bits (78), Expect = 0.082
 Identities = 27/72 (37%), Positives = 32/72 (44%), Gaps = 11/72 (15%)

Query: 29  GGWNTGGSRYPGQGSPGGNRYPPQG----GGGWGQPHGGGWGQPHGGGWGQPHGGGWGQP 84
           G +  G SR       GGN  P  G    GG  G   G G+G  + G  G P GG +G  
Sbjct: 193 GNFGFGDSR-----GGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGS 247

Query: 85  --HGGGWGQGGG 94
             +GGG G  GG
Sbjct: 248 PGYGGGRGGYGG 259



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 1/62 (1%)

Query: 34  GGSRYPGQGSPGGNRYPPQGGGGW-GQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQG 92
           GG+   G    GG  + P  G  + G   G G G+  G G+    GG  G   GG  G G
Sbjct: 192 GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYG 251

Query: 93  GG 94
           GG
Sbjct: 252 GG 253


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.139    0.467 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,860,628
Number of Sequences: 37866
Number of extensions: 870093
Number of successful extensions: 10588
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 273
Number of HSP's that attempted gapping in prelim test: 4186
Number of HSP's gapped (non-prelim): 2566
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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