Guide to the Human Genome
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Name: PRNP Sequence: fasta or formatted (253aa) NCBI GI: 4506113
Description:

prion protein preproprotein

Referenced in:

Additional Brain Proteins

Other entries for this name:
alt mRNA [253aa] prion protein preproprotein
alt mRNA [253aa] prion protein preproprotein
alt mRNA [253aa] prion protein preproprotein
alt mRNA [253aa] prion protein preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.0         10           4
 C cysteine            1.6          4           1
 D aspartate           2.4          6           1
 E glutamate           3.6          9           1
 F phenylalanine       2.8          7           1
 G glycine            17.8         45           4
 H histidine           4.0         10           1
 I isoleucine          3.6          9           2
 K lysine              4.0         10           2
 L leucine             4.7         12           2
 M methionine          4.7         12           2
 N asparagine          4.7         12           2
 P proline             6.7         17           2
 Q glutamine           5.9         15           1
 R arginine            4.3         11           1
 S serine              5.9         15           2
 T threonine           5.1         13           4
 V valine              5.5         14           2
 W tryptophan          3.6          9           1
 Y tyrosine            5.1         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   prion protein preproprotein 
PRNP                  1.000   prion protein preproprotein 
PRNP                  1.000   prion protein preproprotein 
PRNP                  1.000   prion protein preproprotein 
PRNP                  1.000   prion protein preproprotein 
KRT9                  0.070   keratin 9 
KRT2                  0.060   keratin 2 
TAF15                 0.060   TBP-associated factor 15 isoform 2 
TAF15                 0.060   TBP-associated factor 15 isoform 1 
FAM98B                0.055   family with sequence similarity 98, member B isofor...
FAM98A                0.053   hypothetical protein LOC25940 
KRT10                 0.051   keratin 10 
POU4F1                0.051   POU domain, class 4, transcription factor 1 
KRT1                  0.049   keratin 1 
IRS4                  0.049   insulin receptor substrate 4 
HNRNPA3               0.045   heterogeneous nuclear ribonucleoprotein A3 
FLJ37078              0.045   hypothetical protein LOC222183 
PPP1R10               0.045   protein phosphatase 1, regulatory subunit 10 
HNRNPA1               0.043   heterogeneous nuclear ribonucleoprotein A1 isoform b...
AVEN                  0.043   cell death regulator aven 
LBXCOR1               0.041   LBXCOR1 homolog 
HNRNPA0               0.039   heterogeneous nuclear ribonucleoprotein A0 
C6orf174              0.039   hypothetical protein LOC387104 
KRT13                 0.039   keratin 13 isoform b 
KRT13                 0.039   keratin 13 isoform a 
PEF1                  0.039   penta-EF-hand domain containing 1 
HNRNPH3               0.038   heterogeneous nuclear ribonucleoprotein H3 isoform a...
HNRNPH3               0.038   heterogeneous nuclear ribonucleoprotein H3 isoform b...
HNRNPA2B1             0.038   heterogeneous nuclear ribonucleoprotein A2/B1 isofor...
HNRNPA2B1             0.038   heterogeneous nuclear ribonucleoprotein A2/B1 isoform...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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