Guide to the Human Genome
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Search of human proteins with 24797074

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24797074 major histocompatibility complex, class II, DP
alpha 1 precursor [Homo sapiens]
         (260 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24797074 major histocompatibility complex, class II, DP alpha...   535   e-152
gi|52426774 major histocompatibility complex, class II, DR alpha...   304   6e-83
gi|239740916 PREDICTED: similar to MHC HLA-DQ alpha [Homo sapiens]    297   5e-81
gi|169217612 PREDICTED: similar to major histocompatibility comp...   296   9e-81
gi|239740747 PREDICTED: similar to major histocompatibility comp...   296   9e-81
gi|239740697 PREDICTED: similar to major histocompatibility comp...   296   9e-81
gi|113430811 PREDICTED: similar to major histocompatibility comp...   295   3e-80
gi|239740798 PREDICTED: similar to MHC class II antigen [Homo sa...   295   3e-80
gi|18426975 major histocompatibility complex, class II, DQ alpha...   291   4e-79
gi|239740861 PREDICTED: similar to major histocompatibility comp...   291   5e-79
gi|239513953 PREDICTED: similar to major histocompatibility comp...   291   5e-79
gi|11095447 major histocompatibility complex, class II, DQ alpha...   289   1e-78
gi|4504401 major histocompatibility complex, class II, DO alpha ...   283   1e-76
gi|169218140 PREDICTED: similar to major histocompatibility comp...   201   7e-52
gi|239752547 PREDICTED: similar to major histocompatibility comp...   125   3e-29
gi|18765715 major histocompatibility complex, class II, DM alpha...    97   1e-20
gi|24797076 major histocompatibility complex, class II, DP beta ...    79   4e-15
gi|4504399 major histocompatibility complex, class II, DM beta p...    78   9e-15
gi|239758095 PREDICTED: similar to major histocompatibility comp...    74   1e-13
gi|239740749 PREDICTED: similar to major histocompatibility comp...    74   1e-13
gi|239740918 PREDICTED: similar to major histocompatibility comp...    73   3e-13
gi|239748788 PREDICTED: similar to major histocompatibility comp...    72   6e-13
gi|239740863 PREDICTED: similar to major histocompatibility comp...    72   6e-13
gi|239513955 PREDICTED: similar to major histocompatibility comp...    72   6e-13
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ...    71   1e-12
gi|239740859 PREDICTED: similar to major histocompatibility comp...    71   1e-12
gi|239740857 PREDICTED: similar to major histocompatibility comp...    71   1e-12
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...    70   1e-12
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...    70   1e-12
gi|239740920 PREDICTED: similar to major histocompatibility comp...    70   1e-12

>gi|24797074 major histocompatibility complex, class II, DP alpha 1
           precursor [Homo sapiens]
          Length = 260

 Score =  535 bits (1379), Expect = e-152
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED 60
           MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
Sbjct: 1   MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED 60

Query: 61  EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV 120
           EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV
Sbjct: 61  EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV 120

Query: 121 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH 180
           TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH
Sbjct: 121 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH 180

Query: 181 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG 240
           YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
Sbjct: 181 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG 240

Query: 241 TVLIIKSLRSGHDPRAQGTL 260
           TVLIIKSLRSGHDPRAQGTL
Sbjct: 241 TVLIIKSLRSGHDPRAQGTL 260


>gi|52426774 major histocompatibility complex, class II, DR alpha
           precursor [Homo sapiens]
          Length = 254

 Score =  304 bits (778), Expect = 6e-83
 Identities = 148/247 (59%), Positives = 180/247 (72%)

Query: 14  ILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDEDEMFYVDLDKKETV 73
           +L    +A L+S + + AIK +HV   A F      +GEFMF+FD DE+F+VD+ KKETV
Sbjct: 8   VLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETV 67

Query: 74  WHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELGQP 133
           W LEEFG+  SFEAQG LANIA+   NL  + +RSN+T  TN PPEVTV    PVEL +P
Sbjct: 68  WRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP 127

Query: 134 NTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDFYD 193
           N LIC IDKF PPV+NVTWL NG+ VT GV+E++FLPR D+ F KFHYL F+PS ED YD
Sbjct: 128 NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYD 187

Query: 194 CRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHD 253
           CRVEHWGLD+PLLKHWE   P  +PETTE V+CALGL +GLVGII+GT+ IIK LR  + 
Sbjct: 188 CRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNA 247

Query: 254 PRAQGTL 260
              +G L
Sbjct: 248 AERRGPL 254


>gi|239740916 PREDICTED: similar to MHC HLA-DQ alpha [Homo sapiens]
          Length = 255

 Score =  297 bits (761), Expect = 5e-81
 Identities = 147/251 (58%), Positives = 187/251 (74%), Gaps = 1/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G++  EFD DE FYVDL++
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLER 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L  F +   F+ Q  L NIA+L +NLN +I+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVT 124

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLTF+PSA+
Sbjct: 125 LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD 184

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTVLII+ LR
Sbjct: 185 EIYDCKVEHWGLDEPLLKHWEPEIPTPMSELTETVVCALGLSVGLVGIVVGTVLIIRGLR 244

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 245 SVGASRHQGPL 255


>gi|169217612 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 isoform 1 [Homo sapiens]
          Length = 254

 Score =  296 bits (759), Expect = 9e-81
 Identities = 149/251 (59%), Positives = 187/251 (74%), Gaps = 2/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G+F  EFD DE FYVDL++
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYVDLER 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L  F +   F+ Q  L NIA+L +NLN LI+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWKLPLFHR-LRFDPQFALTNIAVLKHNLNILIKRSNSTAATNEVPEVTVFSKSPVT 123

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLTF+PSA+
Sbjct: 124 LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD 183

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTVLII+ LR
Sbjct: 184 EIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLIIRGLR 243

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 244 SVGASRHQGPL 254


>gi|239740747 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  296 bits (759), Expect = 9e-81
 Identities = 149/251 (59%), Positives = 187/251 (74%), Gaps = 2/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G+F  EFD DE FYVDL++
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYVDLER 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L  F +   F+ Q  L NIA+L +NLN LI+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWKLPLFHR-LRFDPQFALTNIAVLKHNLNILIKRSNSTAATNEVPEVTVFSKSPVT 123

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLTF+PSA+
Sbjct: 124 LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD 183

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTVLII+ LR
Sbjct: 184 EIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLIIRGLR 243

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 244 SVGASRHQGPL 254


>gi|239740697 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  296 bits (759), Expect = 9e-81
 Identities = 149/251 (59%), Positives = 187/251 (74%), Gaps = 2/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G+F  EFD DE FYVDL++
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYVDLER 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L  F +   F+ Q  L NIA+L +NLN LI+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWKLPLFHR-LRFDPQFALTNIAVLKHNLNILIKRSNSTAATNEVPEVTVFSKSPVT 123

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLTF+PSA+
Sbjct: 124 LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD 183

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTVLII+ LR
Sbjct: 184 EIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLIIRGLR 243

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 244 SVGASRHQGPL 254


>gi|113430811 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 255

 Score =  295 bits (755), Expect = 3e-80
 Identities = 146/251 (58%), Positives = 186/251 (74%), Gaps = 1/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G++  EFD DE FYVDL++
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLER 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L  F +   F+ Q  L NIA+L +NLN +I+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVT 124

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLTF+PS +
Sbjct: 125 LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSDD 184

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTVLII+ LR
Sbjct: 185 EIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLIIRGLR 244

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 245 SVGASRHQGPL 255


>gi|239740798 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 255

 Score =  295 bits (755), Expect = 3e-80
 Identities = 146/251 (58%), Positives = 186/251 (74%), Gaps = 1/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G++  EFD DE FYVDL++
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLER 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L  F +   F+ Q  L NIA+L +NLN +I+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVT 124

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLTF+PS +
Sbjct: 125 LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSDD 184

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTVLII+ LR
Sbjct: 185 EIYDCKVEHWGLDEPLLKHWEPEIPTPMSELTETVVCALGLSVGLVGIVVGTVLIIRGLR 244

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 245 SVGASRHQGPL 255


>gi|18426975 major histocompatibility complex, class II, DQ alpha 1
           precursor [Homo sapiens]
          Length = 255

 Score =  291 bits (745), Expect = 4e-79
 Identities = 142/251 (56%), Positives = 183/251 (72%), Gaps = 1/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++      Q + P+G++  EFD DE FYVDL++
Sbjct: 5   KALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYVDLER 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KET W   EF +   F+ QG L N+A+  +NLN +I+R N T ATN+ PEVTVF K PV 
Sbjct: 65  KETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSKSPVT 124

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG+ VTEGV+E+ FL ++D+SF K  YLTF+PSA+
Sbjct: 125 LGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD 184

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLDQPLLKHWE + P  M E TETV+CALGL +GL+GI+VGTV II+ LR
Sbjct: 185 EIYDCKVEHWGLDQPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVVGTVFIIQGLR 244

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 245 SVGASRHQGPL 255


>gi|239740861 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  291 bits (744), Expect = 5e-79
 Identities = 147/251 (58%), Positives = 184/251 (73%), Gaps = 2/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G++  EFD DE FYVDL +
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGR 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L    Q F F+ Q  L NIA+L +NLN+LI+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWCLPVLRQ-FRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVT 123

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPN LIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLT +PSAE
Sbjct: 124 LGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAE 183

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTV II+ LR
Sbjct: 184 ESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVFIIRGLR 243

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 244 SVGASRHQGPL 254


>gi|239513953 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  291 bits (744), Expect = 5e-79
 Identities = 147/251 (58%), Positives = 184/251 (73%), Gaps = 2/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G++  EFD DE FYVDL +
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGR 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L    Q F F+ Q  L NIA+L +NLN+LI+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWCLPVLRQ-FRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVT 123

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPN LIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLT +PSAE
Sbjct: 124 LGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAE 183

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +GLVGI+VGTV II+ LR
Sbjct: 184 ESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVFIIRGLR 243

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 244 SVGASRHQGPL 254


>gi|11095447 major histocompatibility complex, class II, DQ alpha 2
           [Homo sapiens]
          Length = 255

 Score =  289 bits (740), Expect = 1e-78
 Identities = 141/251 (56%), Positives = 184/251 (73%), Gaps = 1/251 (0%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y   F Q+H P+G++  EFD DE FYVDL+ 
Sbjct: 5   KALLLGALALTAVMSPCGGEDIVADHVASYGVNFYQSHGPSGQYTHEFDGDEEFYVDLET 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L  F +  SF+ Q  L N+A+  + L  ++++SN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWQLPMFSKFISFDPQSALRNMAVGKHTLEFMMRQSNSTAATNEVPEVTVFSKFPVT 124

Query: 130 LGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAE 189
           LGQPNTLIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D+SF K  YLTF+PSA+
Sbjct: 125 LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD 184

Query: 190 DFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLR 249
           + YDC+VEHWGLD+PLLKHWE + P  M E TET++CALGL +GL+GI+VGTV II+ LR
Sbjct: 185 EIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETLVCALGLSVGLMGIVVGTVFIIQGLR 244

Query: 250 SGHDPRAQGTL 260
           S    R QG L
Sbjct: 245 SVGASRHQGLL 255


>gi|4504401 major histocompatibility complex, class II, DO alpha
           precursor [Homo sapiens]
          Length = 250

 Score =  283 bits (723), Expect = 1e-76
 Identities = 138/244 (56%), Positives = 174/244 (71%), Gaps = 1/244 (0%)

Query: 13  VILRALSLAFLLSLRGAGAIKADHVSTYA-AFVQTHRPTGEFMFEFDEDEMFYVDLDKKE 71
           ++L   +L  LLS + AGA KADH+ +Y  AF Q++  +G+F  EFDE+++F VDL K E
Sbjct: 7   LVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSVDLKKSE 66

Query: 72  TVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELG 131
            VW L EFG    F+ QGGLA IA +  +L+ L++RSN ++A N PP VTV PK  VELG
Sbjct: 67  AVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVELG 126

Query: 132 QPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDF 191
           QPN LIC +D  FPPV+N+TWL NG+ VTEGVA++ F  + D+ F KFHYL FVPSAED 
Sbjct: 127 QPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFVPSAEDV 186

Query: 192 YDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSG 251
           YDC+VEHWGLD PLL+HWE Q PI  P+  ET++CALGL +GLVG +VGTVLII      
Sbjct: 187 YDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVS 246

Query: 252 HDPR 255
             PR
Sbjct: 247 SVPR 250


>gi|169218140 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1, partial [Homo sapiens]
          Length = 153

 Score =  201 bits (510), Expect = 7e-52
 Identities = 95/147 (64%), Positives = 113/147 (76%)

Query: 114 TNDPPEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTD 173
           T + PEVTVF K PV LGQPN LIC +D  FPPV+N+TWL NG  VTEGV+E+ FL ++D
Sbjct: 7   TTEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSD 66

Query: 174 YSFHKFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLG 233
           +SF K  YLT +PSAE+ YDC+VEHWGLD+PLLKHWE + P  M E TETV+CALGL +G
Sbjct: 67  HSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSVG 126

Query: 234 LVGIIVGTVLIIKSLRSGHDPRAQGTL 260
           LVGI+VGTV II+ LRS    R QG L
Sbjct: 127 LVGIVVGTVFIIRGLRSVGASRHQGPL 153


>gi|239752547 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1, partial [Homo sapiens]
          Length = 130

 Score =  125 bits (315), Expect = 3e-29
 Identities = 68/127 (53%), Positives = 88/127 (69%), Gaps = 2/127 (1%)

Query: 11  RAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDEDEMFYVDLDK 69
           +A++L AL+L  ++S  G   I ADHV++Y     Q++ P+G++  EFD DE FYVDL +
Sbjct: 5   KALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGR 64

Query: 70  KETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVE 129
           KETVW L    Q F F+ Q  L NIA+L +NLN+LI+RSN T ATN+ PEVTVF K PV 
Sbjct: 65  KETVWCLPVLRQ-FRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVT 123

Query: 130 LGQPNTL 136
           LGQPN L
Sbjct: 124 LGQPNIL 130


>gi|18765715 major histocompatibility complex, class II, DM alpha
           precursor [Homo sapiens]
          Length = 261

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 65/216 (30%), Positives = 95/216 (43%), Gaps = 9/216 (4%)

Query: 35  DHVSTYAAFVQTHRPTGEFMFEFDEDEMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANI 94
           +H   +  + Q   P+      +DED++F+ D  +   V  L EF  A   + QG    I
Sbjct: 41  NHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEF--ADWAQEQGDAPAI 98

Query: 95  AILNNNLNTLIQRSNHTQATNDP-----PEVTVFPKEPVELGQPNTLICHIDKFFPPVLN 149
                    +IQ+         P     P   VF  +P+E G+PNTL+C +   FPP+L 
Sbjct: 99  LFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLT 158

Query: 150 VTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHW 209
           V W  +  +  EG   +        SF  F YL F P   D + C V H       + +W
Sbjct: 159 VNWQ-HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYW 217

Query: 210 EAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLII 245
             +  +   +  E VLC +   LG++GIIVG VLII
Sbjct: 218 VPRNALP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score = 79.0 bits (193), Expect = 4e-15
 Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 3/123 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P V V P +   L   N L+CH+  F+P  + V W  NG+  T GV  +  +   D++F 
Sbjct: 124 PRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQ 183

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C+VEH  LD P+   W+AQ        ++T+  A G VLGL+  
Sbjct: 184 ILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSD---SARSKTLTGAGGFVLGLIIC 240

Query: 238 IVG 240
            VG
Sbjct: 241 GVG 243


>gi|4504399 major histocompatibility complex, class II, DM beta
           precursor [Homo sapiens]
          Length = 263

 Score = 77.8 bits (190), Expect = 9e-15
 Identities = 76/255 (29%), Positives = 108/255 (42%), Gaps = 36/255 (14%)

Query: 18  LSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTG-EFMFEFDEDEMFYVDLDKKETVWHL 76
           L L   L   GAG   A HV +         P    +   F++D +         T W  
Sbjct: 7   LLLGLSLGCTGAGGFVA-HVESTCLLDDAGTPKDFTYCISFNKDLL---------TCWDP 56

Query: 77  EEFGQA-FSFEAQGGLANIAILN-NNLNTLIQR--------SNHTQA-----TND--PPE 119
           EE   A   F     LAN+   + N  +TL+QR        + HTQ      TN   PP 
Sbjct: 57  EENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQPFWGSLTNRTRPPS 116

Query: 120 VTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVT-EGVAESLFLPRTDYSFHK 178
           V V    P    +P  L C++  F+P  + +TW  NG+LV     A     P  D+++  
Sbjct: 117 VQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNGDWTYQT 176

Query: 179 FHYLTFVPSAEDFYDCRVEHWGLDQPLLKHW-EAQEPIQMPETTETVLCALGLVLGLVGI 237
             +L   PS  D Y C VEH G  +P+L+ W     P+Q   T +  + A+ L LGL+  
Sbjct: 177 LSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQ---TLKVSVSAVTLGLGLIIF 233

Query: 238 IVGTVLIIKSLRSGH 252
            +G   +I   R+GH
Sbjct: 234 SLG---VISWRRAGH 245


>gi|239758095 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 4/140 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P VT+ P     L   N L+C +  F+P  + V W  NG+  T GV  +  +   D++F 
Sbjct: 129 PTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQ 188

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C VEH  L  P+   W AQ      +    +    G VLGL+ +
Sbjct: 189 ILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGI---GGFVLGLIFL 245

Query: 238 IVGTVLIIKSLRSGHDPRAQ 257
            +G ++  +S + G +P+ +
Sbjct: 246 GLGLIIHHRS-QKGEEPQGK 264


>gi|239740749 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 4/140 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P VT+ P     L   N L+C +  F+P  + V W  NG+  T GV  +  +   D++F 
Sbjct: 129 PTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQ 188

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C VEH  L  P+   W AQ      +    +    G VLGL+ +
Sbjct: 189 ILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGI---GGFVLGLIFL 245

Query: 238 IVGTVLIIKSLRSGHDPRAQ 257
            +G ++  +S + G +P+ +
Sbjct: 246 GLGLIIHHRS-QKGEEPQGK 264


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 4/140 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P VT+ P     L   N L+C +  F+P  + V W  N +  T GV  +  +   D++F 
Sbjct: 129 PTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQ 188

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C VEH  L  P++  W AQ      +    +    G VLGL+ +
Sbjct: 189 ILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGI---GGFVLGLIFL 245

Query: 238 IVGTVLIIKSLRSGHDPRAQ 257
            +G ++  +S + G +P+ +
Sbjct: 246 GLGLIIHHRS-QKGEEPQGK 264


>gi|239748788 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 2 [Homo sapiens]
          Length = 281

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 4/140 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P VT+ P     L   N L+C +  F+P  + V W  N +  T GV  +  +   D++F 
Sbjct: 129 PTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQ 188

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C VEH  L  P+   W AQ      +    +    G VLGL+ +
Sbjct: 189 ILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGI---GGFVLGLIFL 245

Query: 238 IVGTVLIIKSLRSGHDPRAQ 257
            +G ++  +S + G +P+ +
Sbjct: 246 GLGLIIHHRS-QKGEEPQGK 264


>gi|239740863 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 4/140 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P VT+ P     L   N L+C +  F+P  + V W  N +  T GV  +  +   D++F 
Sbjct: 129 PTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQ 188

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C VEH  L  P+   W AQ      +    +    G VLGL+ +
Sbjct: 189 ILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGI---GGFVLGLIFL 245

Query: 238 IVGTVLIIKSLRSGHDPRAQ 257
            +G ++  +S + G +P+ +
Sbjct: 246 GLGLIIHHRS-QKGEEPQGK 264


>gi|239513955 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 4/140 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P VT+ P     L   N L+C +  F+P  + V W  N +  T GV  +  +   D++F 
Sbjct: 129 PTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQ 188

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C VEH  L  P+   W AQ      +    +    G VLGL+ +
Sbjct: 189 ILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGI---GGFVLGLIFL 245

Query: 238 IVGTVLIIKSLRSGHDPRAQ 257
            +G ++  +S + G +P+ +
Sbjct: 246 GLGLIIHHRS-QKGEEPQGK 264


>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
           sapiens]
          Length = 266

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 42/140 (30%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P+VTV+P +   L   N L+C +  F+P  + V W  NG+    GV  +  +   D++F 
Sbjct: 126 PKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQ 185

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L  VP + + Y C+VEH  +  PL   W A+      +    V    G VLGL+ +
Sbjct: 186 TLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGV---GGFVLGLLFL 242

Query: 238 IVGTVLIIKSLR--SGHDPR 255
             G  +  ++ +  SG  PR
Sbjct: 243 GAGLFIYFRNQKGHSGLQPR 262


>gi|239740859 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 42/140 (30%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P+VTV+P +   L   N L+C +  F+P  + V W  NG+    GV  +  +   D++F 
Sbjct: 127 PKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQ 186

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L  VP + + Y C+VEH  +  PL   W A+      +    V    G VLGL+ +
Sbjct: 187 TLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGV---GGFVLGLLFL 243

Query: 238 IVGTVLIIKSLR--SGHDPR 255
             G  +  ++ +  SG  PR
Sbjct: 244 GAGLFIYFRNQKGHSGLQPR 263


>gi|239740857 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 42/140 (30%), Positives = 66/140 (47%), Gaps = 5/140 (3%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P+VTV+P +   L   N L+C +  F+P  + V W  NG+    GV  +  +   D++F 
Sbjct: 126 PKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQ 185

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L  VP + + Y C+VEH  +  PL   W A+      +    V    G VLGL+ +
Sbjct: 186 TLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGV---GGFVLGLLFL 242

Query: 238 IVGTVLIIKSLR--SGHDPR 255
             G  +  ++ +  SG  PR
Sbjct: 243 GAGLFIYFRNQKGHSGLQPR 262


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 41/135 (30%), Positives = 64/135 (47%), Gaps = 4/135 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           PEVTV+P +   L   N L+C +  F+P  + V W  NG+    GV  +  +   D++F 
Sbjct: 113 PEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQ 172

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L  VP + + Y C+VEH  +  PL   W A+      +    V    G VLGL+ +
Sbjct: 173 TLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGV---GGFVLGLLFL 229

Query: 238 IVGTVLIIKSLRSGH 252
             G  +  ++ + GH
Sbjct: 230 GAGLFIYFRN-QKGH 243


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 41/135 (30%), Positives = 64/135 (47%), Gaps = 4/135 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           PEVTV+P +   L   N L+C +  F+P  + V W  NG+    GV  +  +   D++F 
Sbjct: 126 PEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQ 185

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L  VP + + Y C+VEH  +  PL   W A+      +    V    G VLGL+ +
Sbjct: 186 TLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGV---GGFVLGLLFL 242

Query: 238 IVGTVLIIKSLRSGH 252
             G  +  ++ + GH
Sbjct: 243 GAGLFIYFRN-QKGH 256


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 3/126 (2%)

Query: 118 PEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFH 177
           P VT+ P     L   N L+C +  F+P  + V W  N +  T GV  +  +   D++F 
Sbjct: 129 PTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQ 188

Query: 178 KFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGI 237
               L   P   D Y C VEH  L  P++  W AQ      +    +    G VLGL+ +
Sbjct: 189 ILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGI---GGFVLGLIFL 245

Query: 238 IVGTVL 243
            +G ++
Sbjct: 246 GLGLII 251


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,326,312
Number of Sequences: 37866
Number of extensions: 460585
Number of successful extensions: 1006
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 902
Number of HSP's gapped (non-prelim): 103
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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