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Search of human proteins with 24233580
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24233580 synaptonemal complex protein 3 [Homo sapiens]
(236 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24233580 synaptonemal complex protein 3 [Homo sapiens] 457 e-129
gi|45504371 family with sequence similarity 9, member B [Homo sa... 77 1e-14
gi|28274703 family with sequence similarity 9, member C [Homo sa... 65 7e-11
gi|28274705 family with sequence similarity 9, member A [Homo sa... 51 8e-07
gi|38373673 synaptonemal complex protein 2 [Homo sapiens] 49 4e-06
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 48 6e-06
gi|46852174 kinesin family member 3A [Homo sapiens] 48 8e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 47 1e-05
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 46 3e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 44 1e-04
gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 43 2e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 43 3e-04
gi|153085395 histone deacetylase 4 [Homo sapiens] 42 4e-04
gi|28269672 serologically defined colon cancer antigen 8 [Homo s... 42 4e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 42 5e-04
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 42 5e-04
gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 42 5e-04
gi|33286444 mastermind-like 2 [Homo sapiens] 41 0.001
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 40 0.001
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 40 0.001
gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein... 40 0.001
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 40 0.001
gi|148664197 coiled-coil domain containing 40 [Homo sapiens] 40 0.001
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] 40 0.001
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 40 0.001
gi|27734911 DAZ interacting protein 1-like [Homo sapiens] 40 0.001
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 40 0.002
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 40 0.002
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 40 0.002
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 40 0.002
>gi|24233580 synaptonemal complex protein 3 [Homo sapiens]
Length = 236
Score = 457 bits (1176), Expect = e-129
Identities = 236/236 (100%), Positives = 236/236 (100%)
Query: 1 MVSSGKKYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSA 60
MVSSGKKYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSA
Sbjct: 1 MVSSGKKYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSA 60
Query: 61 GVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQK 120
GVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQK
Sbjct: 61 GVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQK 120
Query: 121 LNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYE 180
LNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYE
Sbjct: 121 LNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYE 180
Query: 181 QFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEIASVRKSLQSMLF 236
QFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEIASVRKSLQSMLF
Sbjct: 181 QFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEIASVRKSLQSMLF 236
>gi|45504371 family with sequence similarity 9, member B [Homo
sapiens]
Length = 186
Score = 77.4 bits (189), Expect = 1e-14
Identities = 62/207 (29%), Positives = 101/207 (48%), Gaps = 28/207 (13%)
Query: 1 MVSSGKKYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSA 60
M + GKK++ K ++ R + ED D G E E +K +A
Sbjct: 1 MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA 60
Query: 61 GVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQK 120
ED L AKRKR++M K KT N K +H + +Q +RQK
Sbjct: 61 ---ED-------------------LTAKRKRMKM-DKTCSKTKN-KSKHALRKKQLKRQK 96
Query: 121 LNQEYSQQFLTLFQQWDLDMQKAEEQEE----KILNMFRQQQKILQQSRIVQSQRLKTIK 176
+ +S + L + +++ D QK EE+EE +++ +F++QQK QQ R V+ +RLK +K
Sbjct: 97 RDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMK 156
Query: 177 QLYEQFIKSMEELEKNHDNLLTGAQNE 203
L +QF+K++E+ E D + + +E
Sbjct: 157 LLRDQFVKALEDFEDLCDRVFSDEDSE 183
>gi|28274703 family with sequence similarity 9, member C [Homo
sapiens]
Length = 166
Score = 64.7 bits (156), Expect = 7e-11
Identities = 48/158 (30%), Positives = 79/158 (50%), Gaps = 7/158 (4%)
Query: 12 SGKPSVEDQFTRAYDFETEDKKDLSGSEED---VIEGKTAVIEKRRKKRSSAGVVEDMGG 68
+ K +E Q A + E K +S E+ V E K + +R S ++ G
Sbjct: 2 AAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTG 61
Query: 69 EVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQ 128
LE + DI + L AKRKR+E KA + N +I++V +T Q +RQK + S +
Sbjct: 62 VDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKN-RIKNVLRTTQLKRQKRDYRISLK 120
Query: 129 FLTLFQQWDLDMQKAEE---QEEKILNMFRQQQKILQQ 163
+ +++ D QK EE ++E+ + +F++QQK QQ
Sbjct: 121 LPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 51.2 bits (121), Expect = 8e-07
Identities = 44/151 (29%), Positives = 71/151 (47%), Gaps = 12/151 (7%)
Query: 5 GKKYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRK-------KR 57
G+K SRK+ K +E Q RA + KD D E + E R + +R
Sbjct: 48 GRKRSRKAAKAQLEAQ-VRAAPAKKHTGKD---PVRDECEERNPFTETREEDVTDEHGER 103
Query: 58 SSAGVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQ 117
++ G LE + DI K L AKR+ +++ A KT N IE K +Q +
Sbjct: 104 EPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKN-TIERALKKKQLK 162
Query: 118 RQKLNQEYSQQFLTLFQQWDLDMQKAEEQEE 148
RQK + ++++ L + +++ + QK +E EE
Sbjct: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEE 193
Score = 41.6 bits (96), Expect = 6e-04
Identities = 20/63 (31%), Positives = 41/63 (65%)
Query: 141 QKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGA 200
++ EE+EE+ + F+++QK QQ V+S RL+ +K L EQ +K+ ++ + N+ + +
Sbjct: 267 EEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSE 326
Query: 201 QNE 203
++E
Sbjct: 327 ESE 329
>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
Length = 1530
Score = 48.9 bits (115), Expect = 4e-06
Identities = 31/147 (21%), Positives = 70/147 (47%), Gaps = 3/147 (2%)
Query: 88 KRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQE 147
+ K L +T S KT+ Q + + QD R K ++ + + ++ D Q ++ E
Sbjct: 1377 RHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLE 1436
Query: 148 EKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKE 207
++ ++ + +KI Q+ Q + + L KS+ + + + T K++
Sbjct: 1437 KEFVDFW---EKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKED 1493
Query: 208 MAMLQKKIMMETQQQEIASVRKSLQSM 234
M +LQ +++ + ++E+ +VR+ L S+
Sbjct: 1494 MKVLQDRLLKDMLEEELLNVRRELMSV 1520
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 48.1 bits (113), Expect = 6e-06
Identities = 54/244 (22%), Positives = 115/244 (47%), Gaps = 31/244 (12%)
Query: 6 KKYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVED 65
K+ SG S D T + D LS +++ G ++ E RR+K++
Sbjct: 744 KENDNDSGTGSTAD--TSSIDLNLSISSFLSKTKDS---GSISLQETRRQKKT------- 791
Query: 66 MGGEVQNMLEGVGVDINKALL-----AKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQK 120
+ + +++GV V + + + +K + L + L+ ++ + K +Q +Q+
Sbjct: 792 LKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELR----ELRFLQKEEQRAQQQ 847
Query: 121 LNQEYSQQFLTLFQQWDLD-MQKAEEQEEKILNMFRQQQKILQQSRIVQSQRL----KTI 175
LN + QQ +F++++ + M K + +++I N+ +QQ++ +++ + RL K I
Sbjct: 848 LNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRI 907
Query: 176 KQLYEQFIKSMEELEKNHD----NLLTGAQNEFKKEMAMLQKKIMMETQQ-QEIASVRKS 230
K E+ + + + KN N + A E +KE+ +K+ + ++Q QE V+K
Sbjct: 908 KGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQ 967
Query: 231 LQSM 234
Q +
Sbjct: 968 QQEL 971
Score = 31.2 bits (69), Expect = 0.81
Identities = 28/142 (19%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 83 KALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQK 142
+A L K +R E T+ ++ + +I QD R K+ Q +Q+ +Q + M +
Sbjct: 1068 RARLPKIQRSEAKTRMAMFKKSLRINSTATPDQD-RDKIKQFAAQEEK---RQKNERMAQ 1123
Query: 143 AEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQN 202
++ E ++ ++ Q + +++ +Q+++ L E + ++EL++ H L +
Sbjct: 1124 HQKHENQMRDLQLQCEANVRELHQLQNEKCHL---LVEHETQKLKELDEEHSQELKEWRE 1180
Query: 203 EFKKEMAMLQKKIMMETQQQEI 224
+ + L+++ + Q+QE+
Sbjct: 1181 KLRPRKKTLEEEFARKLQEQEV 1202
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 47.8 bits (112), Expect = 8e-06
Identities = 58/230 (25%), Positives = 102/230 (44%), Gaps = 30/230 (13%)
Query: 17 VEDQFTRAYDFETEDKKDLSGSEEDVIE----GKTAVIEKRRKKRSSAGVVEDMGGEVQN 72
+E+ + + E D+SGSEED E G+ EKR+K+R V D E+Q
Sbjct: 367 IEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDG--EKRKKRRGKKKVSPDKMIEMQA 424
Query: 73 MLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTL 132
++ + KAL K E + ++ + + K QQ+ + L + + + +
Sbjct: 425 KID----EERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI 480
Query: 133 FQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEE---L 189
DL + KAEEQE K+L++S + +R K +QL + + +E +
Sbjct: 481 VGGVDL-LAKAEEQE-----------KLLEESNMELEERRKRAEQLRRELEEKEQERLDI 528
Query: 190 EKNHDNLLTGAQNEFKK-----EMAMLQKKIMMETQQQEIASVRKSLQSM 234
E+ + +L AQ + KK M M K M + QQ+ + L+++
Sbjct: 529 EEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENI 578
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 47.0 bits (110), Expect = 1e-05
Identities = 37/131 (28%), Positives = 68/131 (51%), Gaps = 14/131 (10%)
Query: 105 QKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQS 164
Q+++ + QQ Q Q L + +Q+ L QQ L Q E+Q + +QQQ+ LQQ
Sbjct: 162 QQVQEQQRLQQQQEQ-LQTQQAQEQQVLQQQEQLQQQVQEQQ------LLQQQQEQLQQQ 214
Query: 165 RIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
+++Q Q + ++Q +QF + E+L++ LL Q + ++++ Q+ + QQQ +
Sbjct: 215 QLLQQQ--EQLQQ--QQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQ---AQLQQQLL 267
Query: 225 ASVRKSLQSML 235
+ LQ L
Sbjct: 268 EQQQAQLQQQL 278
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/174 (20%), Positives = 81/174 (46%), Gaps = 24/174 (13%)
Query: 69 EVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQ 128
+V E + + + L ++++ ++ + L+ Q + ++ QQ+Q Q+ QQ
Sbjct: 186 QVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ-----QQQ 240
Query: 129 FLTLFQQWDLDMQKAEEQEEKILNMFRQQQK--------ILQQSRIVQSQRLKTIKQLYE 180
L L QQ L Q ++Q+ ++ +QQ+ + QQ ++ Q Q+ + ++Q E
Sbjct: 241 LLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQE 300
Query: 181 QFIKSM-----------EELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQE 223
Q + EE+E + G++ E +++ L+++ +E QQ++
Sbjct: 301 QLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQ 354
Score = 42.0 bits (97), Expect = 5e-04
Identities = 34/154 (22%), Positives = 72/154 (46%), Gaps = 2/154 (1%)
Query: 71 QNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFL 130
Q L+ V + L ++++L+ + Q+ + + Q+ Q + QE QQ
Sbjct: 156 QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQ 215
Query: 131 TLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELE 190
L QQ L Q+ ++Q+E++ +QQ +LQQ +Q Q L+ + +Q + ++ +
Sbjct: 216 LLQQQEQLQQQQFQQQQEQLQQ--QQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQ 273
Query: 191 KNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
LL + +++ L ++ + QQQ++
Sbjct: 274 LQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQL 307
Score = 37.7 bits (86), Expect = 0.009
Identities = 40/210 (19%), Positives = 97/210 (46%), Gaps = 9/210 (4%)
Query: 17 VEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEG 76
V++Q E ++ L +E + + + +++ +++ +++ G Q +L+
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQ 257
Query: 77 VGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQW 136
+ + LL ++++ ++ + L+ Q QQ Q+Q L Q+ Q Q
Sbjct: 258 QQAQLQQQLL-EQQQAQLQQQLLLQQQEQL------QQQQQQQLLQQQQEQLQQQQLQPP 310
Query: 137 DLDMQKAEEQEEKILNMFRQQQKILQQSR--IVQSQRLKTIKQLYEQFIKSMEELEKNHD 194
L+ ++ EE E +++ + ++ L+Q R + + Q L+ ++ + +K EEL++
Sbjct: 311 PLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQ 370
Query: 195 NLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
L Q ++E+ + + + QQQE+
Sbjct: 371 QLEQQQQQLEQQEVQLELTPVELGAQQQEV 400
Score = 35.4 bits (80), Expect = 0.043
Identities = 32/138 (23%), Positives = 64/138 (46%), Gaps = 22/138 (15%)
Query: 114 QQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQ---------------- 157
QQ Q ++L Q L Q D Q ++ Q+EK ++ Q+
Sbjct: 102 QQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQP 161
Query: 158 QKILQQSRIVQSQ-RLKTIKQLYEQFIKSMEELEK--NHDNLLTGAQNEFKKEMAMLQKK 214
Q++ +Q R+ Q Q +L+T + +Q ++ E+L++ LL Q + +++ + Q++
Sbjct: 162 QQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE 221
Query: 215 IMMETQQQEIASVRKSLQ 232
+ QQQ+ ++ LQ
Sbjct: 222 ---QLQQQQFQQQQEQLQ 236
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 45.8 bits (107), Expect = 3e-05
Identities = 48/225 (21%), Positives = 108/225 (48%), Gaps = 39/225 (17%)
Query: 26 DFETEDKKDLSGSEEDVIEGKTAVIEK-RRKKRSSAGVVEDMGGEVQNMLEGVGVDINKA 84
+FE + +++L + +E K +IE+ K++S +E M EV+ + +
Sbjct: 597 EFERQQREEL-----EKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEI----V 647
Query: 85 LLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAE 144
L RK+ E SLK + IE+ K +++K +E L +Q ++++QK
Sbjct: 648 QLQIRKQEE-----SLKRRSFHIENKLKDLLAEKEKFEEE------RLREQQEIELQKKR 696
Query: 145 EQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQL-------YEQFI------KSMEELEK 191
++EE L + + Q++ + + ++++ + ++L EQ+ K +EE EK
Sbjct: 697 QEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEK 756
Query: 192 NHDNLLTGAQNEFKKEMAMLQ-----KKIMMETQQQEIASVRKSL 231
L+ + + +++ M+Q + +E +++++ +R+SL
Sbjct: 757 EQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESL 801
Score = 28.9 bits (63), Expect = 4.0
Identities = 28/146 (19%), Positives = 66/146 (45%), Gaps = 14/146 (9%)
Query: 88 KRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQE 147
K++ E+ + L N +++ +++ +K Q L +Q +QK +
Sbjct: 924 KQRAFEILDRGPLSLDNT----LYQVEKEMEEKEEQ------LAQYQANANQLQKLQATF 973
Query: 148 EKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKE 207
E N+ RQ++K+ ++ + + R K ++ E +++ LE+ H L + + E
Sbjct: 974 EFTANIARQEEKVRKKEKEILESREKQQREALE---RALARLERRHSALQRHSTLGMEIE 1030
Query: 208 MAMLQKKIMMETQQQEIASVRKSLQS 233
QK + + +E + ++ SL++
Sbjct: 1031 -EQRQKLASLNSGSREQSGLQASLEA 1055
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 43.9 bits (102), Expect = 1e-04
Identities = 46/217 (21%), Positives = 100/217 (46%), Gaps = 13/217 (5%)
Query: 18 EDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGV 77
E++ R + E ++ + EE + E + + E+ K R E M + + M
Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE---EMMWEKEEKMRRQE 416
Query: 78 GVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWD 137
+ K +R+ M+ K ++ H + ++Q +K +E + Q+ +
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 138 LDM----QKAEEQEEKILN----MFRQQQKILQQSRIVQSQRLKTIKQLY--EQFIKSME 187
M +K EQEEKI M+RQ++KI +Q +I + ++ + ++++ E+ I+ E
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536
Query: 188 ELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
E+ + + + + K+E M +++ M Q+++I
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/150 (23%), Positives = 74/150 (49%), Gaps = 21/150 (14%)
Query: 88 KRKRLEMYTKASLKTSNQKIEHVWKTQQ---DQRQKLNQEYSQQFLTLFQQWDLDMQKAE 144
KR+ E + K Q E +W+ ++ +Q +K+ ++ + + + D + +K
Sbjct: 518 KRQEQEEMWRQEEKIREQ--EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE-EKIR 574
Query: 145 EQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNE- 203
EQEEK+ +RQ++KI +Q ++ Q E+ I+ EE+ + + + G Q E
Sbjct: 575 EQEEKV---WRQEEKIREQEEKIREQ---------EEKIREQEEMTQEQEEKM-GEQEEK 621
Query: 204 -FKKEMAMLQKKIMMETQQQEIASVRKSLQ 232
++E M +++ M Q+++I K ++
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Score = 38.1 bits (87), Expect = 0.007
Identities = 38/175 (21%), Positives = 80/175 (45%), Gaps = 25/175 (14%)
Query: 51 EKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKA-LLAKRKRLEMYTKASLKTSNQKIEH 109
EK K + +VE E+Q ++ + + +A LL +++L+ + +H
Sbjct: 282 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA-----------EADH 330
Query: 110 VWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQS 169
+ K Q KL + + L W+ Q+ EE+ M+RQ++KI + +Q
Sbjct: 331 LGKELQSVSAKLQAQVEENEL-----WNRLNQQQEEK------MWRQEEKIQEWEEKIQE 379
Query: 170 QRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
Q K +Q E+ I+ EE + + ++ + + +++ M+ +K +Q+E+
Sbjct: 380 QEEKIREQ--EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 432
Score = 37.4 bits (85), Expect = 0.011
Identities = 35/190 (18%), Positives = 86/190 (45%), Gaps = 8/190 (4%)
Query: 39 EEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKA 98
+E++ K + E+ K R + ++ + E + K + K E K
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK- 593
Query: 99 SLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNM---FR 155
++ +KI + Q+Q +K+ ++ ++ ++ +K QEEKI R
Sbjct: 594 -IREQEEKIREQEEMTQEQEEKMGEQ-EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 156 QQQK-ILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKK 214
+Q++ I +Q ++Q Q K +Q E+ + E++++ + + + +++E+ + Q++
Sbjct: 652 EQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710
Query: 215 IMMETQQQEI 224
M+ Q+ +
Sbjct: 711 EKMQEHQEHL 720
Score = 35.8 bits (81), Expect = 0.033
Identities = 29/132 (21%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 114 QQDQRQKLNQEYSQQFLTLFQQWDLDM----QKAEEQEEKILNMFRQQQKILQQSRIVQS 169
+Q+++ + +E +Q+ + + M +K +EQEEK M RQ++KI +Q + ++
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK---MRRQEEKIREQEKKIRE 652
Query: 170 QRLKTIKQ---LYEQFIKSMEELEK---NHDNLLTGAQNEFKKEMAMLQKKIMMETQQQE 223
Q K +Q + EQ K E+ EK + + + ++E M ++++ + Q+++
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Query: 224 IASVRKSLQSML 235
+ ++ L++ +
Sbjct: 713 MQEHQEHLEAAI 724
Score = 33.5 bits (75), Expect = 0.16
Identities = 38/183 (20%), Positives = 76/183 (41%), Gaps = 27/183 (14%)
Query: 18 EDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGV 77
E++ R + + ++ + EE V + + E+ K R + + Q E +
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 78 GVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKT--QQDQRQKLNQEYSQQFLTLFQQ 135
G K + K E K ++ +KI K +Q+++ + +E Q
Sbjct: 616 GEQEEKMCEQEEKMQEQEEK--MRRQEEKIREQEKKIREQEEKIREQEEMMQ-------- 665
Query: 136 WDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQ---LYEQFIKSMEELEKN 192
EQEEK M+ Q++K+ +Q +Q Q K +Q ++EQ ++ ++ EK
Sbjct: 666 ---------EQEEK---MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 193 HDN 195
++
Sbjct: 714 QEH 716
>gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform a [Homo sapiens]
Length = 445
Score = 43.1 bits (100), Expect = 2e-04
Identities = 55/271 (20%), Positives = 119/271 (43%), Gaps = 38/271 (14%)
Query: 2 VSSGKKYSRKSGKPSV---EDQFTRAYDFETE-------DKKDLSGSEEDVIEGKTAVIE 51
VS G + R + SV ++ F R +E+E + ++ E+ I TA+IE
Sbjct: 83 VSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIE 142
Query: 52 KRRKKRSSA-----GVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKT---- 102
+ + SA ++ E++ E ++ +A A+ LE KA+LK
Sbjct: 143 QMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLA 202
Query: 103 SNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQE--EKILNMFRQQQKI 160
+ +K+E + K + + + + ++W K ++ E E+ + +Q++K+
Sbjct: 203 AQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKM 262
Query: 161 LQQSRIVQSQRLKTIKQ----LYEQFIKSMEELEKNH-------DNLLTGAQNEFKKEMA 209
++ + + K I + ++E FI+ EEL K H + L + ++++
Sbjct: 263 TKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVPWRRDQI 322
Query: 210 ------MLQKKIMMETQQQEIASVRKSLQSM 234
+LQ+ ++M+ Q+E+ + L+S+
Sbjct: 323 NRHWHDVLQQLLLMQVMQEELHAQALILESL 353
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.7 bits (99), Expect = 3e-04
Identities = 54/237 (22%), Positives = 114/237 (48%), Gaps = 25/237 (10%)
Query: 6 KKYSRKSGKPSVE-------DQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRS 58
+K +++ PS+E D+ + + E ++K L SE+ I+ + KR+ +R+
Sbjct: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDL-KRKLERA 251
Query: 59 SAGVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQR 118
+ + ++Q + +G ++ + ++E +L Q+ E +W+ Q+++
Sbjct: 252 QLLLPQQ---QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE-EKMWR-QEEKI 306
Query: 119 QKLNQEYSQQFLTLFQQ----WDLDMQKAEEQEEKILN----MFRQQQKILQQSRIVQSQ 170
Q+ ++ +Q L + +Q W + +K EQEEKI M+RQ++KI +Q ++ Q
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQE-EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
Query: 171 RLKTIKQ---LYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
K +Q + EQ K E+ E+ + E K++ M +++ M Q ++I
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI 422
Score = 42.0 bits (97), Expect = 5e-04
Identities = 42/222 (18%), Positives = 97/222 (43%), Gaps = 21/222 (9%)
Query: 28 ETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALLA 87
E EDK + EE + E + + E+ K + + ++Q E + K
Sbjct: 343 EQEDK--MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 88 KRKRLEMYTKASLKTSNQ------KIEHVWKTQQDQRQ--KLNQEYSQQFLTLFQQWDLD 139
+ KR E + K Q + E +W+ ++ R+ ++ Q+ ++ + ++ +
Sbjct: 401 EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE 460
Query: 140 MQKAEEQEEKILNMFRQ----------QQKILQQSRIVQSQRLKTIKQLYEQFIKSMEEL 189
+K +EQEEKI + Q+K+L+Q + Q K +Q E+ + E++
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ-EEKMWEQEEKM 519
Query: 190 EKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEIASVRKSL 231
++ + + + ++E+ + Q++ M+ Q+ + + + L
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 41.2 bits (95), Expect = 8e-04
Identities = 39/158 (24%), Positives = 78/158 (49%), Gaps = 28/158 (17%)
Query: 93 EMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILN 152
E + LK Q+ E +W+ Q+++ + ++ +Q +++Q +K EQEEKI
Sbjct: 311 EKMCEQELKIREQE-EKMWR-QEEKMHEQEEKIREQEDKMWRQ----EEKIREQEEKIRE 364
Query: 153 ----MFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQ------- 201
M+RQ++KI +Q +Q Q ++++ Q K E+ EK + + +
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQE----EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
Query: 202 --NEFKKEMAMLQKKI-----MMETQQQEIASVRKSLQ 232
E ++EM ++KI MM+ Q++++ V + +Q
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Score = 31.2 bits (69), Expect = 0.81
Identities = 39/190 (20%), Positives = 85/190 (44%), Gaps = 29/190 (15%)
Query: 30 EDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALLAKR 89
E ++++ EE + E + + ++ K R +++ ++Q E + K +
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Query: 90 K--RLEMYTKASLKTSNQKIEHVWKT-------------QQDQRQKLNQEYSQQFLTLFQ 134
K R E K K Q+ E +W+ Q+++ Q+ ++ +Q + L+Q
Sbjct: 484 KTWRQEKLLKQEEKIWEQE-EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQ 542
Query: 135 QWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQ-------SQRLKTIKQLYEQFIKSME 187
Q +K +EQE ++ + + K+ Q++ ++ SQRL T+ + + +KS E
Sbjct: 543 Q----EEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQE 598
Query: 188 --ELEKNHDN 195
L++ D+
Sbjct: 599 AQSLQQQQDH 608
>gi|153085395 histone deacetylase 4 [Homo sapiens]
Length = 1084
Score = 42.4 bits (98), Expect = 4e-04
Identities = 27/111 (24%), Positives = 62/111 (55%), Gaps = 1/111 (0%)
Query: 105 QKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQS 164
Q++ + + QQ QRQ L E+ +Q L +Q + + + +Q++++L M QQ+ + Q
Sbjct: 73 QELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQR 132
Query: 165 RIVQSQRLKTI-KQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKK 214
++ + ++ + + KQ EQ ++ ++ EK ++ + + + K + +L KK
Sbjct: 133 KLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKK 183
>gi|28269672 serologically defined colon cancer antigen 8 [Homo
sapiens]
Length = 713
Score = 42.4 bits (98), Expect = 4e-04
Identities = 52/211 (24%), Positives = 99/211 (46%), Gaps = 22/211 (10%)
Query: 35 LSGSEEDVIEGKTAVIEKRRKKRSSAGV----VEDMGGEVQNMLEGVGVDINKALLAKRK 90
L E V + K + I + + +S V + GE++ L ++ ++A R+
Sbjct: 418 LEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHRE 477
Query: 91 RLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKI 150
T L+ +Q+IE + + +Q L QE QQ L ++ L + + + E
Sbjct: 478 -FRAKTNRDLEIKDQEIEKLRIELDESKQHLEQE--QQKAALAREECLRLTELLGESEHQ 534
Query: 151 LNMFRQQQKILQQ--SRIVQSQRLKTIKQLYEQFIKSMEELEKNHDN------LLTGAQN 202
L++ RQ++ +QQ S+ ++Q L+ +Q ++ + ++++E HD LL +QN
Sbjct: 535 LHLTRQEKDSIQQSFSKEAKAQALQA-QQREQELTQKIQQMEAQHDKTENEQYLLLTSQN 593
Query: 203 EF----KKEMAMLQKKIMMETQ--QQEIASV 227
F K+E L KK+ +Q + EIA +
Sbjct: 594 TFLTKLKEECCTLAKKLEQISQKTRSEIAQL 624
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 5e-04
Identities = 50/220 (22%), Positives = 107/220 (48%), Gaps = 18/220 (8%)
Query: 16 SVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLE 75
++ D+ + + E ++K L SE+ I+ + KR+ +R+ + + ++Q +
Sbjct: 210 TITDEELKEKNAELQEKLRLVESEKSEIQLNVKDL-KRKLERAQLLLPQQ---QLQVEAD 265
Query: 76 GVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQ 135
+G ++ + ++E +L Q+ E +W+ Q+++ Q+ ++ +Q L + +Q
Sbjct: 266 RLGKELQSVSAKLQAQVEENELWNLLNQQQE-EKMWR-QEEKIQEQEEKMCEQELKIREQ 323
Query: 136 ----WDLDMQKAEEQEEKILN----MFRQQQKILQQSRIVQSQRLKTIKQ---LYEQFIK 184
W + +K EQEEKI M+RQ++KI +Q ++ Q K +Q + EQ K
Sbjct: 324 EEKMWRQE-EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEK 382
Query: 185 SMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
E+ E+ + E K++ M +++ M Q ++I
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI 422
Score = 42.0 bits (97), Expect = 5e-04
Identities = 42/222 (18%), Positives = 97/222 (43%), Gaps = 21/222 (9%)
Query: 28 ETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALLA 87
E EDK + EE + E + + E+ K + + ++Q E + K
Sbjct: 343 EQEDK--MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 88 KRKRLEMYTKASLKTSNQ------KIEHVWKTQQDQRQ--KLNQEYSQQFLTLFQQWDLD 139
+ KR E + K Q + E +W+ ++ R+ ++ Q+ ++ + ++ +
Sbjct: 401 EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE 460
Query: 140 MQKAEEQEEKILNMFRQ----------QQKILQQSRIVQSQRLKTIKQLYEQFIKSMEEL 189
+K +EQEEKI + Q+K+L+Q + Q K +Q E+ + E++
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ-EEKMWEQEEKM 519
Query: 190 EKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEIASVRKSL 231
++ + + + ++E+ + Q++ M+ Q+ + + + L
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 41.2 bits (95), Expect = 8e-04
Identities = 39/158 (24%), Positives = 78/158 (49%), Gaps = 28/158 (17%)
Query: 93 EMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILN 152
E + LK Q+ E +W+ Q+++ + ++ +Q +++Q +K EQEEKI
Sbjct: 311 EKMCEQELKIREQE-EKMWR-QEEKMHEQEEKIREQEDKMWRQ----EEKIREQEEKIRE 364
Query: 153 ----MFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQ------- 201
M+RQ++KI +Q +Q Q ++++ Q K E+ EK + + +
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQE----EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
Query: 202 --NEFKKEMAMLQKKI-----MMETQQQEIASVRKSLQ 232
E ++EM ++KI MM+ Q++++ V + +Q
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Score = 31.2 bits (69), Expect = 0.81
Identities = 39/190 (20%), Positives = 85/190 (44%), Gaps = 29/190 (15%)
Query: 30 EDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALLAKR 89
E ++++ EE + E + + ++ K R +++ ++Q E + K +
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Query: 90 K--RLEMYTKASLKTSNQKIEHVWKT-------------QQDQRQKLNQEYSQQFLTLFQ 134
K R E K K Q+ E +W+ Q+++ Q+ ++ +Q + L+Q
Sbjct: 484 KTWRQEKLLKQEEKIWEQE-EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQ 542
Query: 135 QWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQ-------SQRLKTIKQLYEQFIKSME 187
Q +K +EQE ++ + + K+ Q++ ++ SQRL T+ + + +KS E
Sbjct: 543 Q----EEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQE 598
Query: 188 --ELEKNHDN 195
L++ D+
Sbjct: 599 AQSLQQQQDH 608
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 42.0 bits (97), Expect = 5e-04
Identities = 54/240 (22%), Positives = 106/240 (44%), Gaps = 32/240 (13%)
Query: 10 RKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGE 69
+KS + + T + E E+ K + G +E T + E ++ ++ + E++ G
Sbjct: 414 KKSSELEEMTKLTNNKEVELEELKKVLGEKE------TLLYENKQFEK----IAEELKGT 463
Query: 70 VQNML------EGVGVDINKALLAKRKRLEMYTKA--SLKTS--NQKIEHVWKTQQDQR- 118
Q ++ E D+ L A + Y+K LKT N+K+++ T +
Sbjct: 464 EQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKL 523
Query: 119 ----QKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKT 174
++L QE S L L Q + D+ ++QEE++L Q+ Q R +
Sbjct: 524 SLENKELTQETSDMTLELKNQQE-DINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 175 IKQLYEQFIKSMEELEKNHDNLLTGAQN------EFKKEMAMLQKKIMMETQQQEIASVR 228
+KQ ++ +++ E+N +NL +N E ++E L+KK E++Q + ++
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Score = 38.1 bits (87), Expect = 0.007
Identities = 48/220 (21%), Positives = 90/220 (40%), Gaps = 27/220 (12%)
Query: 17 VEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEG 76
+++ + + E E KK+++ E+ V + EK K + ++E+ +V N LE
Sbjct: 243 LKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV-NQLE- 300
Query: 77 VGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQW 136
++ +L+ +LK S +K H+ K +D + L + S Q +
Sbjct: 301 -----------EKTKLQ---SENLKQSIEKQHHLTKELEDIKVSLQRSVSTQ-----KAL 341
Query: 137 DLDMQKAEEQ-----EEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEK 191
+ D+Q A + EEK M + K V ++ T+ L E + LEK
Sbjct: 342 EEDLQIATKTICQLTEEKETQM-EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK 400
Query: 192 NHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEIASVRKSL 231
N D L KK + + + ++ E+ ++K L
Sbjct: 401 NEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVL 440
Score = 37.7 bits (86), Expect = 0.009
Identities = 32/155 (20%), Positives = 73/155 (47%), Gaps = 12/155 (7%)
Query: 77 VGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQR--QKLNQEYSQQFLTLFQ 134
V +D+N + K + + + ++ N ++E +K ++D Q L QEY ++ +
Sbjct: 210 VYMDLNNNI---EKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEK 266
Query: 135 QWDLDMQKAEEQEEK------ILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEE 188
Q L + + E+E K +L R + L++ +QS+ LK + K +E+
Sbjct: 267 QVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELED 326
Query: 189 LEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQE 223
++ + ++ Q ++++ + K I T+++E
Sbjct: 327 IKVSLQRSVS-TQKALEEDLQIATKTICQLTEEKE 360
Score = 29.3 bits (64), Expect = 3.1
Identities = 44/198 (22%), Positives = 85/198 (42%), Gaps = 27/198 (13%)
Query: 28 ETEDKK-DLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALL 86
ET D +L +ED+ K E+R K+ +++ +++N LE V ++
Sbjct: 533 ETSDMTLELKNQQEDINNNKKQ--EERMLKQIEN--LQETETQLRNELEYVREEL----- 583
Query: 87 AKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQ 146
K+KR E+ K L S + ++ K +++ + + + QQ + ++K
Sbjct: 584 -KQKRDEV--KCKLDKSEENCNNLRKQVENKNKYIEE---------LQQENKALKKKGTA 631
Query: 147 EEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNE--F 204
E K LN++ + L+ Q+ I Y+ K +E+ + + +NLL +
Sbjct: 632 ESKQLNVYEIKVNKLELELESAKQKFGEITDTYQ---KEIEDKKISEENLLEEVEKAKVI 688
Query: 205 KKEMAMLQKKIMMETQQQ 222
E LQK+I Q +
Sbjct: 689 ADEAVKLQKEIDKRCQHK 706
>gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform b [Homo sapiens]
Length = 422
Score = 42.0 bits (97), Expect = 5e-04
Identities = 51/239 (21%), Positives = 106/239 (44%), Gaps = 26/239 (10%)
Query: 2 VSSGKKYSRKSGKPSV---EDQFTRAYDFETE-------DKKDLSGSEEDVIEGKTAVIE 51
VS G + R + SV ++ F R +E+E + ++ E+ I TA+IE
Sbjct: 83 VSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIE 142
Query: 52 KRRKKRSSA-----GVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKT---- 102
+ + SA ++ E++ E ++ +A A+ LE KA+LK
Sbjct: 143 QMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLA 202
Query: 103 SNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQE--EKILNMFRQQQKI 160
+ +K+E + K + + + + ++W K ++ E E+ + +Q++K+
Sbjct: 203 AQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKM 262
Query: 161 LQQSRIVQSQRLKTIKQ----LYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKI 215
++ + + K I + ++E FI+ EEL K H + T E +K ++Q+++
Sbjct: 263 TKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQS-DTLQLEELRKTKEVMQEEL 320
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Query: 99 SLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQ 158
S+ S K + TQQ Q+Q+ Q+ QQ QQ Q+ ++Q+ I +QQQ
Sbjct: 573 SVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQ 632
Query: 159 K--ILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIM 216
+ I Q + Q Q+ + +Q +Q + ++ + +Q + + + QK ++
Sbjct: 633 QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLL 692
Query: 217 METQQQEIASV 227
+ Q Q IA +
Sbjct: 693 QQMQNQPIAGM 703
Score = 28.5 bits (62), Expect = 5.3
Identities = 17/80 (21%), Positives = 40/80 (50%)
Query: 155 RQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKK 214
+QQQ+ QQ + Q Q+ + +Q +Q S ++ ++ ++ Q + +++ Q++
Sbjct: 595 QQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ 654
Query: 215 IMMETQQQEIASVRKSLQSM 234
+ QQQ+ + QS+
Sbjct: 655 QQQQQQQQQQQPSSQPAQSL 674
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 40.4 bits (93), Expect = 0.001
Identities = 54/230 (23%), Positives = 107/230 (46%), Gaps = 19/230 (8%)
Query: 6 KKYSRKSGKPSVEDQ---FTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGV 62
+K S + VED+ F + E E K +L E+ + V + ++K S G
Sbjct: 1323 QKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL---EKQIATLHAQVADMKKKMEDSVGC 1379
Query: 63 VE---DMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQ 119
+E ++ ++Q LEG+ ++ +A +LE TK L+ Q+++ + QRQ
Sbjct: 1380 LETAEEVKRKLQKDLEGLS-QRHEEKVAAYDKLEK-TKTRLQ---QELDDLLVDLDHQRQ 1434
Query: 120 KL-NQEYSQQFLT--LFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQS--QRLKT 174
N E Q+ L ++ + + AEE++ ++ K L +R ++ ++
Sbjct: 1435 SACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE 1494
Query: 175 IKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEI 224
+++L +QF ME+L + D++ K + A+ Q+ M+TQ +E+
Sbjct: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544
Score = 33.9 bits (76), Expect = 0.13
Identities = 50/203 (24%), Positives = 84/203 (41%), Gaps = 12/203 (5%)
Query: 17 VEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGG---EVQNM 73
+ DQ E K L+ EE++ V E+ +K + + ++ E+Q
Sbjct: 1060 LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119
Query: 74 LEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLF 133
LE NKA K+KR +LKT + QQ+ R K QE + TL
Sbjct: 1120 LESERASRNKA--EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE 1177
Query: 134 QQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNH 193
++ + +E +K + + L+Q++ V++ L+ KQ E EL
Sbjct: 1178 EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKA-NLEKAKQTLE---NERGELANEV 1233
Query: 194 DNLLTG---AQNEFKKEMAMLQK 213
LL G ++++ KK A LQ+
Sbjct: 1234 KVLLQGKGDSEHKRKKVEAQLQE 1256
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/128 (22%), Positives = 65/128 (50%), Gaps = 8/128 (6%)
Query: 116 DQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQ-QSRIVQSQRLKT 174
+++ K+ ++ + L + +QWD + ++Q E+ + RQ+ LQ Q ++++R +
Sbjct: 300 EKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQK 359
Query: 175 IKQLYEQFI--KSMEELEKNHDNLLTGAQNEFKKEMAMLQKKI-----MMETQQQEIASV 227
+ + + KS E+E+ LT E ++++ LQ ++ E Q++EI +
Sbjct: 360 QRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREYQEKEIQRL 419
Query: 228 RKSLQSML 235
K+L+ L
Sbjct: 420 NKALEEAL 427
>gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 2 [Homo sapiens]
Length = 602
Score = 40.4 bits (93), Expect = 0.001
Identities = 42/195 (21%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 44 EGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGV--DINKALLAKRKRLEMYTKASLK 101
E T + +R R +D+ +Q+ L+ G + ++A +K+ KA+
Sbjct: 143 ELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKK-----KANQL 197
Query: 102 TSNQKIEHVWKTQQDQRQK-LNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKI 160
+S K WK +Q R++ L + QF FQQ L+ + E + ++
Sbjct: 198 SSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEH-------LKGERAR 250
Query: 161 LQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQ 220
QQ SQ + T+K+ +Q ++ +E+LE++ L E + ++ ++
Sbjct: 251 WQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHL 310
Query: 221 QQEIASVRKSLQSML 235
++E+ V LQ+ +
Sbjct: 311 RKELERVAGELQAQV 325
>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 1 [Homo sapiens]
Length = 632
Score = 40.4 bits (93), Expect = 0.001
Identities = 42/195 (21%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 44 EGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGV--DINKALLAKRKRLEMYTKASLK 101
E T + +R R +D+ +Q+ L+ G + ++A +K+ KA+
Sbjct: 144 ELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKK-----KANQL 198
Query: 102 TSNQKIEHVWKTQQDQRQK-LNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKI 160
+S K WK +Q R++ L + QF FQQ L+ + E + ++
Sbjct: 199 SSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEH-------LKGERAR 251
Query: 161 LQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQ 220
QQ SQ + T+K+ +Q ++ +E+LE++ L E + ++ ++
Sbjct: 252 WQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHL 311
Query: 221 QQEIASVRKSLQSML 235
++E+ V LQ+ +
Sbjct: 312 RKELERVAGELQAQV 326
>gi|148664197 coiled-coil domain containing 40 [Homo sapiens]
Length = 1142
Score = 40.4 bits (93), Expect = 0.001
Identities = 48/219 (21%), Positives = 102/219 (46%), Gaps = 26/219 (11%)
Query: 26 DFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKAL 85
D + + +L + + I +T +IE+++ G++ + +++ M+ +G + L
Sbjct: 699 DQDVKKVNELITNSQSEISRRTILIERKQ------GLINFLNKQLERMVSELGGEEVGPL 752
Query: 86 LAKRKRLEMY--------TKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWD 137
+ KRL +A + + E V TQ+ + Q + + S++ L + +Q
Sbjct: 753 ELEIKRLSKLIDEHDGKAVQAQVTWLRLQQEMVKVTQEQEEQLASLDASKKELHIMEQKK 812
Query: 138 LDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLL 197
L ++ EQE+K +QK ++ LK + L + S EELE+N N +
Sbjct: 813 LRVESKIEQEKK-------EQKEIEHHMKDLDNDLKKLNMLMNKNRCSSEELEQN--NRV 863
Query: 198 TGAQNEFKKEM-AMLQKKIMMETQQQEIASVRKSLQSML 235
T +NEF + + A ++ I M+ + +++ + +L + L
Sbjct: 864 T--ENEFVRSLKASERETIKMQDKLNQLSEEKATLLNQL 900
>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
Length = 625
Score = 40.4 bits (93), Expect = 0.001
Identities = 48/204 (23%), Positives = 90/204 (44%), Gaps = 31/204 (15%)
Query: 51 EKRRKKRSS--------AGVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKT 102
EK +KK+ S + D +++ + + D +KA LA+ ++L+ L+
Sbjct: 180 EKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEAD-HKAQLARTQKLQQ----ELEA 234
Query: 103 SNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKIL---NMFRQQQK 159
+NQ + + +DQRQ E++ L Q + A+EQ E +L N R
Sbjct: 235 ANQSLAEL----RDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLA 290
Query: 160 ILQQSRIVQSQRLKTIKQL-------YEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQ 212
L+Q + ++Q L +++ +Q E+L D+L + Q + +L+
Sbjct: 291 ALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLE 350
Query: 213 --KKIMMETQQ--QEIASVRKSLQ 232
++I E +Q QE+ RKS +
Sbjct: 351 QLQEIGQEKEQLTQELQEARKSAE 374
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 40.4 bits (93), Expect = 0.001
Identities = 48/204 (23%), Positives = 90/204 (44%), Gaps = 31/204 (15%)
Query: 51 EKRRKKRSS--------AGVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKT 102
EK +KK+ S + D +++ + + D +KA LA+ ++L+ L+
Sbjct: 233 EKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEAD-HKAQLARTQKLQQ----ELEA 287
Query: 103 SNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKIL---NMFRQQQK 159
+NQ + + +DQRQ E++ L Q + A+EQ E +L N R
Sbjct: 288 ANQSLAEL----RDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLA 343
Query: 160 ILQQSRIVQSQRLKTIKQL-------YEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQ 212
L+Q + ++Q L +++ +Q E+L D+L + Q + +L+
Sbjct: 344 ALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLE 403
Query: 213 --KKIMMETQQ--QEIASVRKSLQ 232
++I E +Q QE+ RKS +
Sbjct: 404 QLQEIGQEKEQLTQELQEARKSAE 427
>gi|27734911 DAZ interacting protein 1-like [Homo sapiens]
Length = 767
Score = 40.4 bits (93), Expect = 0.001
Identities = 23/96 (23%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Query: 144 EEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNE 203
+E+ E+ L R+ Q + +++ I +++ + +K+L+E+ + +EL++ + L +
Sbjct: 310 DEESEEWLRQARELQALREKTEIQKTEWKRKVKELHEEHMAEKKELQEENQRLQASLSQD 369
Query: 204 FKKEMAMLQKKI-----MMETQQQEIASVRKSLQSM 234
KK A Q +I ++ Q + IAS + +QS+
Sbjct: 370 QKKAAAQSQCQISTLRAQLQEQARIIASQEEMIQSL 405
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/204 (17%), Positives = 99/204 (48%), Gaps = 10/204 (4%)
Query: 30 EDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALLAKR 89
E +K + EE + E + E++R+++ E+ E + + + + K+
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 90 KRLEMYTKASLKTSNQKI----EHVWKTQQ---DQRQKLNQ--EYSQQFLTLFQQWDLDM 140
+ + + +KI E +W+ ++ +Q +K+ + E ++ + Q+ + M
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 141 QKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGA 200
+ EE+ ++ M RQ++KI +Q ++ Q+ K I++ E+ + E++ + + +
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK-IREQEEKIWEQEEKIREQEEMMQEQE 612
Query: 201 QNEFKKEMAMLQKKIMMETQQQEI 224
+ +++E M +++ M+ Q++++
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKM 636
Score = 38.5 bits (88), Expect = 0.005
Identities = 48/225 (21%), Positives = 105/225 (46%), Gaps = 23/225 (10%)
Query: 18 EDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGV 77
E++ R + E ++ + EE + E + + E+ K R ++ + +++ E +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 78 GVDINKALLAKRKRLE--MYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQ 135
K +RLE M+ K ++ H + ++Q +K +E + Q+
Sbjct: 359 WEKEEKM-----RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413
Query: 136 WDLDM----QKAEEQEEKILN----MFRQQQKILQQSRIVQSQRLKTIKQLY--EQFIKS 185
+ M +K EQEEKI M+RQ++KI +Q +I + ++ + ++++ E+ I+
Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473
Query: 186 MEEL----EKNHDNLLTGAQNE--FKKEMAMLQKKIMMETQQQEI 224
EE+ EK H+ Q E +++E M ++ + Q++++
Sbjct: 474 QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Score = 37.4 bits (85), Expect = 0.011
Identities = 29/147 (19%), Positives = 72/147 (48%), Gaps = 21/147 (14%)
Query: 100 LKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILN------- 152
++ +KI + Q+Q +K+ ++ ++ + ++ +K EQEEKI
Sbjct: 532 IREQEEKIREQEEMMQEQEEKMGEQ--EEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE 589
Query: 153 ----MFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEM 208
++ Q++KI +Q ++Q Q K ++EQ K E+ EK + + ++E
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEK----MWEQEEKMCEQEEKMQEQ----EEKMRRQEE 641
Query: 209 AMLQKKIMMETQQQEIASVRKSLQSML 235
M ++++ + Q++++ ++ L++ +
Sbjct: 642 KMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 36.2 bits (82), Expect = 0.025
Identities = 36/165 (21%), Positives = 75/165 (45%), Gaps = 25/165 (15%)
Query: 51 EKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKA-LLAKRKRLEMYTKASLKTSNQKIEH 109
EK K + +VE E+Q ++ + + +A LL +++L+ + +H
Sbjct: 221 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA-----------EADH 269
Query: 110 VWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQS 169
+ K Q KL + + L W+ Q+ EE+ M+RQ++KI + +Q
Sbjct: 270 LGKELQSVSAKLQAQVEENEL-----WNRLNQQQEEK------MWRQEEKIQEWEEKIQE 318
Query: 170 QRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKK 214
Q K +Q E+ I+ EE + + ++ + + +++ M+ +K
Sbjct: 319 QEEKIREQ--EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 9/119 (7%)
Query: 105 QKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQS 164
Q++ + + QQ Q+Q L E+ +Q L +Q ++ +QK +Q++++L +QQQ++L
Sbjct: 79 QELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEML-AAKQQQEMLAAK 137
Query: 165 RIVQSQRLKTIKQLYEQFIKSMEELEKN--HDNLLTGAQNEFKKEMAMLQKKIMMETQQ 221
R Q L+ +Q +Q EELEK LL E KE A+ ++ + Q+
Sbjct: 138 R---QQELEQQRQREQQ---RQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQE 190
Score = 31.2 bits (69), Expect = 0.81
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 8/75 (10%)
Query: 155 RQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKK 214
R+QQ LQQ + Q+ + KQL E +K HD+L + + +K + Q+
Sbjct: 73 REQQ--LQQELLALKQQQQLQKQLL------FAEFQKQHDHLTRQHEVQLQKHLKQQQEM 124
Query: 215 IMMETQQQEIASVRK 229
+ + QQ+ +A+ R+
Sbjct: 125 LAAKQQQEMLAAKRQ 139
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 9/119 (7%)
Query: 105 QKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQQS 164
Q++ + + QQ Q+Q L E+ +Q L +Q ++ +QK +Q++++L +QQQ++L
Sbjct: 78 QELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEML-AAKQQQEMLAAK 136
Query: 165 RIVQSQRLKTIKQLYEQFIKSMEELEKN--HDNLLTGAQNEFKKEMAMLQKKIMMETQQ 221
R Q L+ +Q +Q EELEK LL E KE A+ ++ + Q+
Sbjct: 137 R---QQELEQQRQREQQ---RQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQE 189
Score = 31.2 bits (69), Expect = 0.81
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 8/75 (10%)
Query: 155 RQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKKEMAMLQKK 214
R+QQ LQQ + Q+ + KQL E +K HD+L + + +K + Q+
Sbjct: 72 REQQ--LQQELLALKQQQQLQKQLL------FAEFQKQHDHLTRQHEVQLQKHLKQQQEM 123
Query: 215 IMMETQQQEIASVRK 229
+ + QQ+ +A+ R+
Sbjct: 124 LAAKQQQEMLAAKRQ 138
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 40.0 bits (92), Expect = 0.002
Identities = 37/206 (17%), Positives = 96/206 (46%), Gaps = 9/206 (4%)
Query: 30 EDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGVGVDINKALLAKR 89
E ++ + EE + + + + E+ + R E+ GE + ++ + K R
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ----EEQMGEQEEQVQKQEEQVQKQEEQMR 258
Query: 90 KRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQW---DLDMQKAEEQ 146
K+ E + + Q+ + + + +Q ++++ E +Q +Q + M++ EEQ
Sbjct: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318
Query: 147 -EEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFK 205
E+ M +Q++++ +Q + Q+ + KQ EQ + E+++K + + + K
Sbjct: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ-EEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 206 KEMAMLQKKIMMETQQQEIASVRKSL 231
+E M +++ M Q++++ ++ +
Sbjct: 378 QEEQMRKQEEQMRKQEEQMGEQKEQM 403
Score = 36.2 bits (82), Expect = 0.025
Identities = 34/191 (17%), Positives = 85/191 (44%), Gaps = 13/191 (6%)
Query: 18 EDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGV 77
E+Q + + E ++ + EE +++ K ++ ++ G E+ E + +
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQMLKQK-----EQTEQEEQTGEQEEQMREQEEQMREQ 308
Query: 78 GVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQ-----QDQRQKLNQEYSQQFLTL 132
+ + R++ E K + QK E +W+ + Q+++ +E Q+
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQK-EQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ 367
Query: 133 FQQWDLDMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEELEKN 192
++ + M+K EEQ K R+Q++ + + + ++ + +++ EQ + E++ K
Sbjct: 368 VRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427
Query: 193 HDNLLTGAQNE 203
+++ G Q E
Sbjct: 428 EEHM--GEQKE 436
Score = 31.2 bits (69), Expect = 0.81
Identities = 34/221 (15%), Positives = 94/221 (42%), Gaps = 19/221 (8%)
Query: 18 EDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGV 77
E+Q + + E ++ + EE V + + + ++ + R E M + + ML+
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE---EQMREQEEQMLKQK 282
Query: 78 GVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWD 137
+ +++ + ++ +++ + ++Q +++ ++ Q + Q W+
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 138 L---------DMQKAEEQEEKILNMFRQQQKILQQSRIVQSQRLKTIKQLYEQFIKSMEE 188
M + EEQ +K Q++++ +Q ++ Q + KQ EQ K E+
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQK------QEEQVRKQEEQMRKQEEQMRKQ-EEQMRKQEEQ 395
Query: 189 LEKNHDNLLTGAQNEFKKEMAMLQKKIMMETQQQEIASVRK 229
+ + + + + ++E M ++K M Q++ + ++
Sbjct: 396 MGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.125 0.325
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,269,173
Number of Sequences: 37866
Number of extensions: 307389
Number of successful extensions: 3267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 472
Number of HSP's that attempted gapping in prelim test: 2114
Number of HSP's gapped (non-prelim): 1214
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.