BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo sapiens] (1833 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 3851 0.0 gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 3298 0.0 gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 1644 0.0 gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 1100 0.0 gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ... 920 0.0 gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s... 882 0.0 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 102 3e-21 gi|57864582 hornerin [Homo sapiens] 93 2e-18 gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 82 6e-15 gi|62122917 filaggrin family member 2 [Homo sapiens] 75 4e-13 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 69 3e-11 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 69 3e-11 gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 67 2e-10 gi|161016767 mucin 21 [Homo sapiens] 66 3e-10 gi|17017963 forkhead box P2 isoform I [Homo sapiens] 66 4e-10 gi|60097902 filaggrin [Homo sapiens] 65 6e-10 gi|149999352 forkhead box P2 isoform II [Homo sapiens] 64 1e-09 gi|22538413 forkhead box P2 isoform III [Homo sapiens] 63 3e-09 gi|11761629 fibrinogen, alpha polypeptide isoform alpha prepropr... 63 3e-09 gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop... 63 3e-09 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 62 5e-09 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 60 1e-08 gi|110347429 mediator complex subunit 12 [Homo sapiens] 60 3e-08 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 60 3e-08 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 4e-08 gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 59 6e-08 gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 59 6e-08 gi|4504733 insulin receptor substrate 4 [Homo sapiens] 58 1e-07 gi|33286444 mastermind-like 2 [Homo sapiens] 58 1e-07 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 57 2e-07 >gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo sapiens] Length = 1833 Score = 3851 bits (9987), Expect = 0.0 Identities = 1833/1833 (100%), Positives = 1833/1833 (100%) Query: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP Sbjct: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60 Query: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG Sbjct: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120 Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS Sbjct: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180 Query: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG Sbjct: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240 Query: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS Sbjct: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300 Query: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS Sbjct: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360 Query: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG Sbjct: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420 Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST Sbjct: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480 Query: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN Sbjct: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540 Query: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC Sbjct: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600 Query: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT Sbjct: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660 Query: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS Sbjct: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720 Query: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI Sbjct: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780 Query: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW Sbjct: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840 Query: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN Sbjct: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900 Query: 901 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP 960 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP Sbjct: 901 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP 960 Query: 961 GWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGV 1020 GWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGV Sbjct: 961 GWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGV 1020 Query: 1021 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS 1080 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS Sbjct: 1021 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS 1080 Query: 1081 SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTL 1140 SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTL Sbjct: 1081 SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTL 1140 Query: 1141 PFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGL 1200 PFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGL Sbjct: 1141 PFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGL 1200 Query: 1201 FGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ 1260 FGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ Sbjct: 1201 FGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ 1260 Query: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL Sbjct: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320 Query: 1321 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM 1380 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM Sbjct: 1321 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM 1380 Query: 1381 DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII 1440 DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII Sbjct: 1381 DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII 1440 Query: 1441 PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 1500 PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV Sbjct: 1441 PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 1500 Query: 1501 TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA 1560 TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA Sbjct: 1501 TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA 1560 Query: 1561 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR 1620 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR Sbjct: 1561 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR 1620 Query: 1621 SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN 1680 SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN Sbjct: 1621 SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN 1680 Query: 1681 LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS 1740 LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS Sbjct: 1681 LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS 1740 Query: 1741 APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS 1800 APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS Sbjct: 1741 APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS 1800 Query: 1801 SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1833 SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI Sbjct: 1801 SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1833 >gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo sapiens] Length = 1723 Score = 3298 bits (8551), Expect = 0.0 Identities = 1623/1836 (88%), Positives = 1637/1836 (89%), Gaps = 116/1836 (6%) Query: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP Sbjct: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60 Query: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG Sbjct: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120 Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS Sbjct: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180 Query: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG Sbjct: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240 Query: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS Sbjct: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300 Query: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS Sbjct: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360 Query: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG Sbjct: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420 Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST Sbjct: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480 Query: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN Sbjct: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540 Query: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC Sbjct: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600 Query: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT Sbjct: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660 Query: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS Sbjct: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720 Query: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI Sbjct: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780 Query: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASG Sbjct: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASG-- 838 Query: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900 SW GP P P + PS S+W Sbjct: 839 ----------------SWG-GPPPPPPGNVRPSN-------------------SSWSS-- 860 Query: 901 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNE--- 957 GP P P P + S S S D+GTSAWG+PN Sbjct: 861 ----------------GPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904 Query: 958 SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEED 1017 + + + G N P + +SKSMQDGWGESDGPVTGARHPSWEEEED Sbjct: 905 KNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEED 964 Query: 1018 GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTED 1077 GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTED Sbjct: 965 GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTED 1024 Query: 1078 NPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK 1137 NPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK Sbjct: 1025 NPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK 1084 Query: 1138 LTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGS 1197 G G+ S +P L+ S S Sbjct: 1085 -----GGSHGLFGNSTAQSRGLHTPVQPLNSSPS-------------------------- 1113 Query: 1198 HGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNV 1257 L V P SP + A SMLKQFPNSGLSPGLFNV Sbjct: 1114 -------------LRAQVPPQFISPQVSA-------------SMLKQFPNSGLSPGLFNV 1147 Query: 1258 GPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV 1317 GPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV Sbjct: 1148 GPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV 1207 Query: 1318 SALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSS 1377 SALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSS Sbjct: 1208 SALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSS 1267 Query: 1378 GGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQF 1437 GGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQF Sbjct: 1268 GGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQF 1327 Query: 1438 DIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESD 1497 DIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESD Sbjct: 1328 DIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESD 1387 Query: 1498 PYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHS 1557 PYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHS Sbjct: 1388 PYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHS 1447 Query: 1558 TSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSST 1617 TSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSST Sbjct: 1448 TSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSST 1507 Query: 1618 APRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTF 1677 APRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTF Sbjct: 1508 APRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTF 1567 Query: 1678 HLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAA 1737 HLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAA Sbjct: 1568 HLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAA 1627 Query: 1738 TPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPN 1797 TPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPN Sbjct: 1628 TPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPN 1687 Query: 1798 YSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1833 YSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI Sbjct: 1688 YSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1723 >gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo sapiens] Length = 1029 Score = 1644 bits (4256), Expect = 0.0 Identities = 811/903 (89%), Positives = 816/903 (90%), Gaps = 57/903 (6%) Query: 931 SKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS 990 S +A VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS Sbjct: 184 SGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS 243 Query: 991 KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 1050 KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL Sbjct: 244 KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 303 Query: 1051 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 1110 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI Sbjct: 304 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 363 Query: 1111 MRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSG 1170 MRKDRSGFRPPNSKDMGTTDSGPYFEK G G+ S +P L+ S Sbjct: 364 MRKDRSGFRPPNSKDMGTTDSGPYFEK-----GGSHGLFGNSTAQSRGLHTPVQPLNSSP 418 Query: 1171 STLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP 1230 S L V P SP + A Sbjct: 419 S---------------------------------------LRAQVPPQFISPQVSA---- 435 Query: 1231 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 1290 SMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ Sbjct: 436 ---------SMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 486 Query: 1291 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 1350 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM Sbjct: 487 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 546 Query: 1351 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 1410 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA Sbjct: 547 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 606 Query: 1411 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 1470 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK Sbjct: 607 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 666 Query: 1471 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 1530 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN Sbjct: 667 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 726 Query: 1531 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 1590 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI Sbjct: 727 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 786 Query: 1591 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 1650 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL Sbjct: 787 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 846 Query: 1651 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 1710 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN Sbjct: 847 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 906 Query: 1711 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 1770 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST Sbjct: 907 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 966 Query: 1771 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1830 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS Sbjct: 967 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1026 Query: 1831 DSI 1833 DSI Sbjct: 1027 DSI 1029 Score = 325 bits (833), Expect = 2e-88 Identities = 185/302 (61%), Positives = 206/302 (68%), Gaps = 33/302 (10%) Query: 2 REKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 61 +EKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS Sbjct: 38 QEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 97 Query: 62 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 121 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG Sbjct: 98 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 157 Query: 122 AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSP 181 AGPPPCTAPGANPNNAQVTGALLQSESGTAP + A + S WG S+ G Sbjct: 158 AGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG--- 214 Query: 182 NPIHIWDKVIVDGSDMEEW---PCIASKDTESSSENTTDN--------NSASNPGSEKST 230 W ++ G+ W P A + +S++ D A +P E+ Sbjct: 215 -----WGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEE 269 Query: 231 LPG--STTSNKGKGSQCQSASSGN------ECNLGVWKSD----PKAKSVQSSN--STTE 276 G +TT ++G S SAS G +C+L +D P AK + S TE Sbjct: 270 DGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTE 329 Query: 277 NN 278 +N Sbjct: 330 DN 331 Score = 45.1 bits (105), Expect = 6e-04 Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 27/122 (22%) Query: 633 VWDIEEVPRPE------GKSDKGTEGWESAATQTKNSGGWGDAPS--------QSNQMKS 678 VW P P+ G+ ++ + GW ++ GWG+ P+ S M+ Sbjct: 189 VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQD 248 Query: 679 GWGELSAST------EWKDPKNTGGWN------DYKNNNSSNWG-GGRPDEKTPSSWNEN 725 GWGE W++ ++ G WN ++NS++WG GG+ K N Sbjct: 249 GWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNN 308 Query: 726 PS 727 S Sbjct: 309 DS 310 Score = 43.9 bits (102), Expect = 0.001 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 9/111 (8%) Query: 684 SASTEWKDPKNTG-GWNDYKNNNSSNWGGGRPDEKTPSSWNENP-SKDQGWGGGRQPNQG 741 + ++ W +P + GW + + +S G G P++ N S GWG P G Sbjct: 200 NGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTG 259 Query: 742 WSSGKNGWGEEVD----QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788 + W EE D T S +S+ S WG+GG+ ++ GGN Sbjct: 260 --ARHPSWEEEEDGGVWNTTGSQGSASSHNSAS-WGQGGKKQMKCSLKGGN 307 Score = 41.2 bits (95), Expect = 0.009 Identities = 68/308 (22%), Positives = 101/308 (32%), Gaps = 54/308 (17%) Query: 670 PSQSNQMKSGWGELSASTEWKDPKN---TGGWNDYKNNNSSNWGGGRPD--EKTPSSWNE 724 P + G G + +P N TG ++ + W P + S+W E Sbjct: 148 PPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGE 207 Query: 725 NPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWG 784 GWG + G S+ GWG N+ +S S GWGE Sbjct: 208 PNESSPGWG--EMDDTGAST--TGWGNTPANAPNAMKPNSKSMQ-DGWGE---------- 252 Query: 785 NGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPP 844 + G + A WE+ + WN TG Q ++ + AS GG Sbjct: 253 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN---------------SASWGQGGKK 297 Query: 845 PPPPGNVRPSNSSWS-------SGPQPATPKDEEPSGWEEPSPQSIS-RKMDIDDGTSAW 896 +N SW S + ++ PS + S S+S +K D+D Sbjct: 298 QMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNL 357 Query: 897 GDPNSYNYKNVNLWDKNSQGGPAPREPNLPT----PMTSKSASVWSKSTPPAPDNGTSAW 952 GD N ++ K+ G P ++ T P K S A G Sbjct: 358 GDFN-------DIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTP 410 Query: 953 GEPNESSP 960 +P SSP Sbjct: 411 VQPLNSSP 418 Score = 32.0 bits (71), Expect = 5.7 Identities = 39/160 (24%), Positives = 60/160 (37%), Gaps = 7/160 (4%) Query: 295 PGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG 354 P G N +P S+P P V GT+ ++TD + + +T G S S Sbjct: 681 PWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTD--HQLLRDNTTGSNSSLNTSLPSPGA 738 Query: 355 VNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNP--MENKGMPFGMGLGNTSRSTDAP 410 + S +H+T P +T S + NP + NK + NT+ P Sbjct: 739 WPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPP 798 Query: 411 SQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNG 450 T + K S S A R G T + S + ++G Sbjct: 799 PGLT-NPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 837 >gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] Length = 1962 Score = 1100 bits (2846), Expect = 0.0 Identities = 776/2038 (38%), Positives = 1039/2038 (50%), Gaps = 308/2038 (15%) Query: 7 EREEQLMEDKKRKKEDKKKKEATQK-VTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN 65 + EEQLME+KK+KK+DKKKKEA QK TEQK KVPE KPS+SQP A+ + S + Sbjct: 22 QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANS-NNGTSTATS 80 Query: 66 GGNNAKRVAVPNGQP------------------------------PSAARYMPREVPPRF 95 NNAKR N QP P A PREVPPRF Sbjct: 81 TNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRF 140 Query: 96 RCQQDHKVLLKRGQPPPPSCMLLGGGA------GPPPCTAPGANPNNAQVTGALLQSESG 149 R Q+HK LLKRGQ P LG NN +V + QS+ Sbjct: 141 R-HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDIN 199 Query: 150 TAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTE 209 ST G S+Y NS G +S TS + + + V+ D S+ E WP D E Sbjct: 200 ---HSTSG----SHYENSQRGPVSS----TSDSSTNCKNAVVSDLSEKEAWPSAPGSDPE 248 Query: 210 SSSENTTDNNSAS--------------NPGSEKSTLPGSTTSNKGKGSQ------CQSAS 249 +SE D +SAS N G EK L ST G GSQ S + Sbjct: 249 LASE-CMDADSASSSESERNITIMASGNTGGEKDGLRNST----GLGSQNKFVVGSSSNN 303 Query: 250 SGNECNLGVWKSDPKA------KSVQSSNSTTE-NNNGLGNWRNVSGQDRIGPGSGFSNF 302 G+ + G W A SV + S +E +NN + W VS G S Sbjct: 304 VGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSS--NGGLNPSTL 361 Query: 303 NPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQT-------------------- 342 N SN AWP L G + KG + + +S + Q ST+GQ Sbjct: 362 NSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWG 421 Query: 343 SREQQSKMENAGVNFV-VSGREQAQIHNTDGPKNGNTNSLNLSSPN---------PMENK 392 S ++ + E +G V SG+ Q GP N TN + S PN P N Sbjct: 422 SLQETCESEVSGTQKVSFSGQPQNITTEMTGP-NNTTNFMTSSLPNSGSVQNNELPSSNT 480 Query: 393 G-----------MPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQS 441 G M G+ TS S S G+ K+G GS+G G G S S Sbjct: 481 GAWRVSTMNHPQMQAPSGMNGTSLS----HLSNGESKSG--GSYGTTWGAYG----SNYS 530 Query: 442 NSGNNGNNGKEREDSWKGASVQKS-TGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGN 500 +G NG+ D+ +Q G ++ N GG W G +S WG GN Sbjct: 531 GDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGN 590 Query: 501 KMTSGVSQGEWKQP---TGSDELKIGEWSG-PNQPNSS----------TGAWDN--QKGH 544 SG S+ W P TG++ L EW+ P+ +S+ T W + ++ Sbjct: 591 GANSGGSRRGWGTPAQNTGTN-LPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQ 649 Query: 545 PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604 +Q N Q+ W ++ + S+ +STG + G+ +S + RR D +L Sbjct: 650 GSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKI-----DQHTLL 704 Query: 605 QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664 Q++++RTDLDPRVLSN+GWGQT IKQ+T WD E PR E K+D GTE W S+ATQT NSG Sbjct: 705 QSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSG 764 Query: 665 GWGDAPS---QSNQMKSGWGELSASTEWKDPKNT---GGWNDYKNN----NSSNWGGGRP 714 D S SGWG+ + W D K + GGW D S+ WG + Sbjct: 765 ACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKE 824 Query: 715 DEKTPSSWNENPSKDQGWGGGRQPNQGWS----------SGKNGWGEEVDQTKNSNWESS 764 ++ ++WN++ QGWG G++ +QGWS S N WGE K+S+ S Sbjct: 825 EK---AAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEA--NKKSSSGGSD 879 Query: 765 ASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKR---SPAWNETGRQPNS--WNKQ 819 + + VSGW E G+ TWGN N + +S GW++ + S W + + S W Sbjct: 880 SDRSVSGWNELGKTSSFTWGNNINPNNSS--GWDESSKPTPSQGWGDPPKSNQSLGWGDS 937 Query: 820 HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPS 879 + P Q + GSWG PP +P + W GP PA K+EEP+GWEEPS Sbjct: 938 SKPVSSPDW--NKQQDIVGSWG----IPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPS 991 Query: 880 PQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREP-----NLPTP---MTS 931 P+SI RKM+IDDGTSAWGDP+ YNYKNVN+W+KN G + + L TP +++ Sbjct: 992 PESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISN 1051 Query: 932 KSAS-------VWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANA 982 K AS W + + PA DNGTSAWG+P +S P WGE +ST+ WG++ Sbjct: 1052 KEASSGSGWGEPWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGP 1111 Query: 983 PNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDG--GVWNTTGSQGSASSHN------ 1034 K KSMQDGW D P+ G R WEEEED G+WN+ SQ SS N Sbjct: 1112 QALSKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTK 1171 Query: 1035 -SASWGQGGKKQM--KCSLKGGN--NDSWMNPLAKQFSNMGLL--SQTEDNPSSKMDLSV 1087 +S G GKK+ + +KGGN ++W+NP KQFSN+ S E+ S+KMDLS Sbjct: 1172 KMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSG 1231 Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147 G L DK+ ++DK ++N+GD+N + K G RP SK+ + + PYF+K DG Sbjct: 1232 GMLQDKRMEIDKHSLNIGDYNRTVGKG-PGSRPQISKE-SSMERNPYFDK--------DG 1281 Query: 1148 CLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQGGSHGLF--GNS 1204 + DE+ F S S KL PS S LPN +LG+I GL QN + RQ G+ +F GN+ Sbjct: 1282 IVADESQNMQFMSSQSMKLPPSNSALPNQALGSI-AGLGMQNLNSVRQNGNPSMFGVGNT 1340 Query: 1205 TAQSRGL-HTPVQPLNSS-PSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLS 1262 AQ RG+ P QPL+SS P+LRAQVPP +SPQV S+LK PN+G + P Sbjct: 1341 AAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG------GLNPLFG 1394 Query: 1263 PQQIAMLSQLPQIPQFQLACQL--LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320 PQQ+AML+QL Q+ Q QL LL QQQ+ Q+QR + R QQ+QQ R +S Sbjct: 1395 PQQVAMLNQLSQLNQLSQISQLQRLLAQQQR---AQSQRSVPSGNRPQQDQQ-GRPLSVQ 1450 Query: 1321 QQQQQQ----------QQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIP- 1369 QQ QQ +Q+ P + P H K LDN++P+ P+LQ KGP P Sbjct: 1451 QQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHT----TPELQ-KGPSPI 1505 Query: 1370 ----GYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAP 1425 + G +S ++ M +SR ++WT+ ++ + + + N K+GAI + Sbjct: 1506 NAFSNFPIGLNS-NLNVNMDMNSIKEPQSRLRKWTT-VDSISVNTSLDQNSSKHGAI-SS 1562 Query: 1426 GKTRGGSPYNQFDIIPGDTL-GGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGV 1484 G SP+ +D + T G GD W AKSP + SS+ +WPPEF+PG Sbjct: 1563 GFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSP------NGSSSVNWPPEFRPGE 1616 Query: 1485 PWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWP 1544 PWKG NIDPE+DPYVTPGSV+ + + + + DH LRD +GS+SSLNT+LPS AW Sbjct: 1617 PWKGYPNIDPETDPYVTPGSVINNLSINTVREVDH--LRDRNSGSSSSLNTTLPSTSAWS 1674 Query: 1545 YSASDN----SFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPR 1600 + N + STSA+ D K TWSP + + T L++++WK + +N T R Sbjct: 1675 SIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTN--TSLAHELWKVPLPPKNITAPSR 1732 Query: 1601 PPPGLTNPKPS-SPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQI 1659 PPPGLT KP S W ++ R GWG D+R S+W + S R + WLVL NLTPQI Sbjct: 1733 PPPGLTGQKPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQI 1792 Query: 1660 DGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFAT 1719 DGSTLRT+CMQHGPL+TFHLNL G AL+RYS+K+E KAQ +LHMCVLGNTTILAEFA+ Sbjct: 1793 DGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFAS 1852 Query: 1720 DDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSA 1779 ++E+SRF AQ+Q T P+ GWQSL + Q++ + + F T L W+ + Sbjct: 1853 EEEISRFFAQSQSLT-------PSPGWQSLGSSQSRLGSL-DCSHSFSSRTDLNHWNGAG 1904 Query: 1780 -GGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPL---LPGDLLGGGSDSI 1833 G++ DL G SLWG P+YS+SLWG P+ DP + SP+P+ L D LGGG +S+ Sbjct: 1905 LSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962 >gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo sapiens] Length = 1726 Score = 920 bits (2378), Expect = 0.0 Identities = 686/1820 (37%), Positives = 887/1820 (48%), Gaps = 305/1820 (16%) Query: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267 T+ ++ N N + S +S L ++ G ++ ++G+ L S Sbjct: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66 Query: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327 V + + G G +N G G N NPN+NP+AWP L EGT G Sbjct: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121 Query: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370 + S+ + VS +GQ Q +S + VS Q Q NT Sbjct: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181 Query: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415 DGP N TN +N SSPNP+ N GM GMG G + + SQ +G Sbjct: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238 Query: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474 G S WG + G T G SNSG + NG D+ A K GS S Sbjct: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288 Query: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530 S G +W+ GP WG G N + G W P+ S + GEW P Sbjct: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346 Query: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578 PN + + N KG P +Q P W +++SS + G S GS NH Sbjct: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406 Query: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638 GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE Sbjct: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464 Query: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690 PR E K+D GTE W AATQ NSGG D S + SGW + A+T W Sbjct: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524 Query: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734 D P G W D ++ + + W G E +W E P K Q WG Sbjct: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584 Query: 735 GRQPNQGWSSGKNGWGEEV-------DQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786 G++ N WS+G W + D KN S W++ +++ SGW + ++ WGN Sbjct: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644 Query: 787 GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845 N W E K P N + PQ +WGG Sbjct: 645 TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGGA-- 682 Query: 846 PPPGNVRPSNSSWSSGPQPATPKDE-EPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904 +V+ + + W GP P KD E +GWEEPSP SI RKM+IDDGTSAWGDP++YN Sbjct: 683 ---ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739 Query: 905 KNVNLWDKNSQGGPAPREPNLPTPMT---------------------------------- 930 K VN+WD+N+ + N T T Sbjct: 740 KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSG 799 Query: 931 --------SKSASVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPA 980 SK+ + W + + P+ DNGT+AWG+P S GWG+ G P Sbjct: 800 WGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPV 859 Query: 981 NAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQ 1040 A KP SKSMQ+GWG S G WE+EE G VWN SQ S SS +SWG Sbjct: 860 AASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSSWGN 915 Query: 1041 GGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSLSDK 1093 KK ++ +K G +++W M+ L KQ ++MG + + + +D ++ +L +K Sbjct: 916 APKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEK 975 Query: 1094 KFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEA 1153 K DVDKR + + D N + K G RPP SK+ + D + +K DG L +E Sbjct: 976 KVDVDKRGLGVTDHNGMAAKPL-GCRPPISKE-SSVDRPTFLDK--------DGGLVEEP 1025 Query: 1154 PCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQ--GGSHGLFGNS-TAQSR 1209 SPF PSPS KL S S LP+ +LG I +GL QN ++RQ G+ G+FGNS AQ+R Sbjct: 1026 TPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQAR 1085 Query: 1210 GLHTP----VQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQLSP 1263 + P VQPLNSS PSLRAQVP QF+SPQV A +L+ N GL+P L ++P Sbjct: 1086 TMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLT--SPINP 1142 Query: 1264 QQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQ 1323 Q + ML+QL Q+ QLA Q L Q QQQ+LQ QR +S ++RQQ EQQ+AR ++ LQQQ Sbjct: 1143 QHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMRQQ-EQQVARTITNLQQQ 1195 Query: 1324 QQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG---- 1366 QQ QRQ P H HP K +D+ + GLPDLQTK Sbjct: 1196 IQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS 1255 Query: 1367 -------PIPGYGSGFSSGGMDYGMVGGKE----AGTESRFKQWT--SMMEGLPSVATQ- 1412 P+ G + MD M GG + ++SR QWT + M+ LPS A+ Sbjct: 1256 PNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPL 1313 Query: 1413 EANMHKNGAIVA------PGKTRGGSPYNQFDIIPGDTLGGHTGPA-GDSWLPAKSPPTN 1465 E N K+GAI PGK+ Y ++D+I A SW AKS ++ Sbjct: 1314 EQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSD-SD 1372 Query: 1466 KIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQLLRD 1524 KI S S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T + I D + LL+ Sbjct: 1373 KI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKS 1431 Query: 1525 NTTGSNSSLNTSLPSPGAWP-----YSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPT 1579 + SS N +LPS AWP YS+S +S + S + K D KSTWS P H Sbjct: 1432 GGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQA 1491 Query: 1580 HLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWS 1639 LS+++WK RN+T RPPPGLTNPKPSS W + S GW S +S S WS Sbjct: 1492 SLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWS 1541 Query: 1640 DGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKA 1699 S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKA Sbjct: 1542 TDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKA 1601 Query: 1700 QTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPV 1759 Q +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P P + WQS Sbjct: 1602 QKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ----- 1649 Query: 1760 GPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHR 1813 P L+ G S GL G W++ G G + LW G P YSSSLWG P+ +D Sbjct: 1650 -PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRV 1705 Query: 1814 MGSPAP---LLPGDLLGGGS 1830 +GSP P LLPGDLL G S Sbjct: 1706 IGSPTPLTTLLPGDLLSGES 1725 Score = 43.9 bits (102), Expect = 0.001 Identities = 96/497 (19%), Positives = 178/497 (35%), Gaps = 86/497 (17%) Query: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186 C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ + Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536 Query: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238 W I W A+++ +S + + + G + + P + Sbjct: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594 Query: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293 G G S+S + N W +D +++T N+G GN N Sbjct: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649 Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344 NP +N W ++ G + A + ++N S ++V QT Sbjct: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697 Query: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396 +Q+ E G + ++ DG P N N ++N+ N N + Sbjct: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754 Query: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454 T+ +T S +T +T G R P SG G N + E Sbjct: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGW---GEMPNVHSKTE 811 Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514 +SW G ST N G+ +G S+ + WG+ + V+ G P Sbjct: 812 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 858 Query: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563 S ++ G SG ++ N ST W++++G + + + WG ++ Sbjct: 859 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 917 Query: 564 STGSEVGGQSTGSNHKA 580 G + G +++G +A Sbjct: 918 KKGLQKGMKTSGKQDEA 934 >gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo sapiens] Length = 1690 Score = 882 bits (2280), Expect = 0.0 Identities = 672/1818 (36%), Positives = 868/1818 (47%), Gaps = 337/1818 (18%) Query: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267 T+ ++ N N + S +S L ++ G ++ ++G+ L S Sbjct: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66 Query: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327 V + + G G +N G G N NPN+NP+AWP L EGT G Sbjct: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121 Query: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370 + S+ + VS +GQ Q +S + VS Q Q NT Sbjct: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181 Query: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415 DGP N TN +N SSPNP+ N GM GMG G + + SQ +G Sbjct: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238 Query: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474 G S WG + G T G SNSG + NG D+ A K GS S Sbjct: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288 Query: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530 S G +W+ GP WG G N + G W P+ S + GEW P Sbjct: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346 Query: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578 PN + + N KG P +Q P W +++SS + G S GS NH Sbjct: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406 Query: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638 GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE Sbjct: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464 Query: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690 PR E K+D GTE W AATQ NSGG D S + SGW + A+T W Sbjct: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524 Query: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734 D P G W D ++ + + W G E +W E P K Q WG Sbjct: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584 Query: 735 GRQPNQGWSSGKNGWGEEV-------DQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786 G++ N WS+G W + D KN S W++ +++ SGW + ++ WGN Sbjct: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644 Query: 787 GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845 N W E K P N + PQ +WGG Sbjct: 645 TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGGA-- 682 Query: 846 PPPGNVRPSNSSWSSGPQPATPKDE-EPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904 +V+ + + W GP P KD E +GWEEPSP SI RKM+IDDGTSAWGDP++YN Sbjct: 683 ---ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739 Query: 905 KNVNLWDKNSQGGPAPREPNLPTPMT---------------------------------- 930 K VN+WD+N+ + N T T Sbjct: 740 KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKV 799 Query: 931 -----------SKSASVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGN 977 SK+ + W + + P+ DNGT+AWG+P S GWG+ G Sbjct: 800 SSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAG 859 Query: 978 TPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSAS 1037 P A KP SKSMQ+GWG S G WE+EE G VWN SQ S SS +S Sbjct: 860 APVAASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSS 915 Query: 1038 WGQGGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSL 1090 WG KK ++ +K G +++W M+ L KQ ++MG + + + +D ++ +L Sbjct: 916 WGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSAL 975 Query: 1091 SDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLG 1150 +KK DVDKR + + D N + K G RPP SK+ + D + +K DG L Sbjct: 976 LEKKVDVDKRGLGVTDHNGMAAKPL-GCRPPISKE-SSVDRPTFLDK--------DGGLV 1025 Query: 1151 DEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQ--GGSHGLFGNS-TA 1206 +E SPF PSPS KL S S LP+ +LG I +GL QN ++RQ G+ G+FGNS A Sbjct: 1026 EEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAA 1085 Query: 1207 QSRGLHTP----VQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQ 1260 Q+R + P VQPLNSS PSLRAQVP QF+SPQV A +L+ N GL+P L Sbjct: 1086 QARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLT--SP 1142 Query: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320 ++PQ + ML+QL Q+ QLA Q L Q QQQ+LQ QR +S ++RQQ EQQ+AR ++ L Sbjct: 1143 INPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMRQQ-EQQVARTITNL 1195 Query: 1321 QQQQQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG- 1366 QQQ QQ QRQ P H HP K +D+ + GLPDLQTK Sbjct: 1196 QQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQ 1255 Query: 1367 ----------PIPGYGSGFSSGGMDYGMVGGKE----AGTESRFKQWT--SMMEGLPSVA 1410 P+ G + MD M GG + ++SR QWT + M+ LPS A Sbjct: 1256 QSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAA 1313 Query: 1411 TQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIPGDTLGGHTGPA-GDSWLPAKSP 1462 + E N K+GAI PGK+ Y ++D+I A SW AKS Sbjct: 1314 SPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSD 1373 Query: 1463 PTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQL 1521 ++KI S S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T + I D + L Sbjct: 1374 -SDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYL 1431 Query: 1522 LRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHL 1581 L+ + K D KSTWS P H L Sbjct: 1432 LK----------------------------------SGGKLSDIKSTWSSGPTSHTQASL 1457 Query: 1582 SNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 1641 S+++WK RN+T RPPPGLTNPKPSS W + S GW S +S S WS Sbjct: 1458 SHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWSTD 1507 Query: 1642 GSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQT 1701 S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKAQ Sbjct: 1508 TSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQK 1567 Query: 1702 ALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGP 1761 +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P P + WQS P Sbjct: 1568 SLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ------P 1614 Query: 1762 ALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHRMG 1815 L+ G S GL G W++ G G + LW G P YSSSLWG P+ +D +G Sbjct: 1615 RLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRVIG 1671 Query: 1816 SPAP---LLPGDLLGGGS 1830 SP P LLPGDLL G S Sbjct: 1672 SPTPLTTLLPGDLLSGES 1689 Score = 44.3 bits (103), Expect = 0.001 Identities = 95/497 (19%), Positives = 177/497 (35%), Gaps = 83/497 (16%) Query: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186 C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ + Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536 Query: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238 W I W A+++ +S + + + G + + P + Sbjct: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594 Query: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293 G G S+S + N W +D +++T N+G GN N Sbjct: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649 Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344 NP +N W ++ G + A + ++N S ++V QT Sbjct: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697 Query: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396 +Q+ E G + ++ DG P N N ++N+ N N + Sbjct: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754 Query: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454 T+ +T S +T +T G R P S G N + E Sbjct: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTE 814 Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514 +SW G ST N G+ +G S+ + WG+ + V+ G P Sbjct: 815 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 861 Query: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563 S ++ G SG ++ N ST W++++G + + + WG ++ Sbjct: 862 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 920 Query: 564 STGSEVGGQSTGSNHKA 580 G + G +++G +A Sbjct: 921 KKGLQKGMKTSGKQDEA 937 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 102 bits (254), Expect = 3e-21 Identities = 152/827 (18%), Positives = 299/827 (36%), Gaps = 40/827 (4%) Query: 146 SESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIAS 205 S+S A D + +N ++S G+G NNG N K D SD + S Sbjct: 505 SDSKGAEDDDSDSTSDTNNSDSN-GNG---NNGNDDNDKSDSGKGKSDSSDSDSSDSSNS 560 Query: 206 KDTESSSEN-TTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264 D+ SS++ ++D+NS+S+ S S S+ S+ S +S ++ + SD Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD-- 618 Query: 265 AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGA 324 + +S +S +E+++ + ++ S S S+ + +SN S S + Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678 Query: 325 LETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLS 384 +D+SNSS + ++ + S + + ++D + N+NS + Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESS-----------DSSDSSDSDSSDSSDSSNSNSSDSD 727 Query: 385 SPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSG 444 S N ++ ++S S+++ S + S S ++ +D S S+ Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD--SSNSSDS 785 Query: 445 NNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTS 504 N+ +N + DS + S+ S + S +++ S+ S + DS+D+ + +S Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845 Query: 505 GVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSS 564 S GSD N +SS + + + N + S SS Sbjct: 846 DSSD-------GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898 Query: 565 TGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWG 624 S+ S+ S++ + SSDS NS S D + S D SN+ Sbjct: 899 NSSD--SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956 Query: 625 QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684 D + SD S ++ + +S D+ SN S + S Sbjct: 957 SNSSDSSNSSDSSD----SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS--SDSS 1010 Query: 685 ASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSS 744 S++ + ++ +D N++ S+ D S +++ + SS Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070 Query: 745 GKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSP 804 + + D +++S+ S++ S + + + ++ + D S Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130 Query: 805 AWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQP 864 +++ NS + + ++S S + SNSS SS Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD--SSNSSDSSDSSD 1188 Query: 865 ATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPN 924 ++ + + S D D + + +S + + N ++S + + Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN---ESSDSSDSSDSSD 1245 Query: 925 LPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGAS 971 S +S S ST + D S N ++ G D+ S Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292 Score = 102 bits (254), Expect = 3e-21 Identities = 141/792 (17%), Positives = 280/792 (35%), Gaps = 46/792 (5%) Query: 133 NPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192 N NN S G + S + +SN ++S+ S + S++ S + D Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588 Query: 193 DGSDMEEWPCIASKDTESSSE--NTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASS 250 D SD + S D+ SS+ +++D++ +S+ S+ S ++ + K S SS Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648 Query: 251 GNECNLGVWKSDPKAKSVQSSNST-TENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPS 309 + N S + S SS+S+ + +++ + N S S S + +S+ S Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708 Query: 310 AWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHN 369 + +S + ++D+SNSS + + S N+ + S + + Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768 Query: 370 TDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAAR 429 + +++S N S N N+S S+D+ + S + S S ++ Sbjct: 769 DSSDSSDSSDSSNSSDSNDS-----------SNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817 Query: 430 GPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQ 489 S + S S+ ++ +N + DS + S S N++ S+ S + Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877 Query: 490 DSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPEN 549 DS+D+ + N+ ++ + + SD + S + + S+ + D+ + +N Sbjct: 878 DSSDS--SDSNESSNSSDSSDSSNSSDSDS---SDSSNSSDSSDSSNSSDSSESSNSSDN 932 Query: 550 QGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLS 609 ++ SS+S+ S S+ S+ + SSDS NS S Sbjct: 933 SNSSD------SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS----------------D 970 Query: 610 RTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDA 669 D SN+ D + SD S ++ + NS ++ Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030 Query: 670 PSQSNQM-KSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSK 728 S+ S + S S++ D N+ +D +++ S+ D S +++ Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090 Query: 729 DQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788 + SS + + D + +SN S+ S N + + + Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150 Query: 789 ASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPP 848 + + D S +++ +S N ++S S Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1210 Query: 849 GNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQS----ISRKMDIDDGTSAWGDPNSYNY 904 + S+ S S + E S + S S S D D + + D N + Sbjct: 1211 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD 1270 Query: 905 KNVNLWDKNSQG 916 + N+ G Sbjct: 1271 SQSKSGNGNNNG 1282 Score = 100 bits (250), Expect = 1e-20 Identities = 133/680 (19%), Positives = 262/680 (38%), Gaps = 57/680 (8%) Query: 133 NPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192 N +++ + + S+S + DS+ +++S+ +NS+ S +S ++ +S + Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSS-DSSSSSDSSNSSDSSDSSDSSNSSESS--------- 702 Query: 193 DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGN 252 D SD + +S ++SS+ N++D++S+++ S S+ ++ + + S+ S + Sbjct: 703 DSSDSSDSD--SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760 Query: 253 ECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWP 312 N SD S S +S + N++ + N S S SN + +S+ S Sbjct: 761 SSN----SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS--- 813 Query: 313 ALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDG 372 + + + +D+SNSS S +S S + G + S R + +++D Sbjct: 814 ----DSSDSDSSNSSDSSNSS-DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS-NSSDS 867 Query: 373 PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPS 432 + ++++ + SS + N+ N+S S+D+ + S D S S + S Sbjct: 868 SDSSDSSNSSDSSDSSDSNES-------SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920 Query: 433 GTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKN--------DSWDNNNRSTGGSW 484 + S S+ +N ++ DS + S+ S N DS D+N+ + S Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980 Query: 485 NFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH 544 N + + + S S SD + S + ++S+ + D+ Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040 Query: 545 PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604 ++ ++ + SS S+ S S+ S+ + SSDS S S D Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100 Query: 605 QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664 + S D S++ D + SD S ++ + +S Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160 Query: 665 GWGDAPSQSNQM-------------KSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGG 711 D+ S+ S + S S++ D ++ +D +++ S+ Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220 Query: 712 GRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWES-SASKPVS 770 D S NE+ N SS + + D T +SN ES S SK + Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSN---SSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277 Query: 771 GWGEGGQNEIGTWGNGGNAS 790 G G ++ + G+ N S Sbjct: 1278 GNNNGSDSDSDSEGSDSNHS 1297 Score = 98.2 bits (243), Expect = 6e-20 Identities = 112/616 (18%), Positives = 233/616 (37%), Gaps = 28/616 (4%) Query: 146 SESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIAS 205 S+S + +S + +SN ++S+ S +S ++ +S + D S+ + + Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772 Query: 206 KDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLG-VWKSDPK 264 S S N++D+N +SN + S +SN S +S + N S Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832 Query: 265 AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGA 324 + S SS+S+ +++ G+ + S + S S+ + +SN S S + Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892 Query: 325 LETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLS 384 +D+SNSS S+ S + ++ + ++ N+ N + +S + Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSS---------DSSESSNSSDNSNSSDSSNSSD 943 Query: 385 SPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSG 444 S + ++ ++S S+D+ ++ D S S + S + S S++ Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003 Query: 445 NNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTS 504 ++ ++ + DS + S+ S N S +++ + S + + + + S Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063 Query: 505 GVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSS 564 S SD E S + ++S+ + D+ ++ ++ + SS+S Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123 Query: 565 TGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWG 624 + S S+ S+ + SSDS +S S D + S D SN+ Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-- 1181 Query: 625 QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684 D + SD S ++ + +S D+ S+ S + S Sbjct: 1182 ----------DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS--SDSS 1229 Query: 685 ASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSS 744 S E D ++ +D N++ S+ + + S+ + N D G N G S Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSS----DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285 Query: 745 GKNGWGEEVDQTKNSN 760 + G + + + + + Sbjct: 1286 DSDSEGSDSNHSTSDD 1301 Score = 96.7 bits (239), Expect = 2e-19 Identities = 161/894 (18%), Positives = 320/894 (35%), Gaps = 54/894 (6%) Query: 145 QSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIA 204 +S G P+S+ + ++ ANS + +SS S N D +GSD Sbjct: 458 KSMQGDDPNSS-DESNGNDDANSESDNNSSSRGDASYNSDESKDNG--NGSD-------- 506 Query: 205 SKDTESS-SENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263 SK E S++T+D N++ + G+ + + S+ GKG S S ++ + SD Sbjct: 507 SKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDS 566 Query: 264 KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323 SNS++++++ + + S D S SN + +S+ S Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSD----SSDSSNSSDSSDSS-------------- 608 Query: 324 ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL 383 D+S+SS S+ S+ SK E+ + S + + +++D N +++ + Sbjct: 609 ----DSSDSSD--SSDSSDSKSDSSKSESDSSD-SDSKSDSSDSNSSDSSDNSDSSDSSN 661 Query: 384 SSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNS 443 SS + + ++ S + S + D S S + S + S SNS Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721 Query: 444 GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMT 503 ++ ++ DS ++ S+ S + S +++ + S N + + + Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781 Query: 504 SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSS 563 S S SD + S + + S+ + D+ + + + + S S Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841 Query: 564 STGSEVG-GQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTG 622 S S+ G + S++++ SS+S +S S D + S D SN+ Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901 Query: 623 WGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGE 682 + ++ D + S+ S ++ + NS D+ SN S Sbjct: 902 DSDSSDSSNSS-DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960 Query: 683 LSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGW 742 S+++ N+ +D N++ S+ D S + + N Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020 Query: 743 SSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKR 802 SS + D + +S+ S+ S N + + ++ + D Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080 Query: 803 SPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGP 862 S +++ NS + ++S S + S+ S S Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140 Query: 863 QPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPRE 922 + E S + S S S D D + + +S N + + +S + Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDS--SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198 Query: 923 PNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANA 982 + S +S S S+ + + +S + NESS D + +S + + ++ Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD- 1257 Query: 983 PNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSA 1036 +S S D ESD + G + + S+GS S+H+++ Sbjct: 1258 ------SSDSTSDSNDESDSQSKSG------NGNNNGSDSDSDSEGSDSNHSTS 1299 Score = 96.7 bits (239), Expect = 2e-19 Identities = 148/856 (17%), Positives = 298/856 (34%), Gaps = 40/856 (4%) Query: 207 DTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAK 266 D +SS+ + N+ A++ S+ G + N +S +GN SD K Sbjct: 463 DDPNSSDESNGNDDANSESDNNSSSRGDASYNSD-----ESKDNGNG-------SDSKGA 510 Query: 267 SVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALE 326 S+ST++ NN N +G D + +S+ + + +S + Sbjct: 511 EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570 Query: 327 TDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSP 386 + +SNSS+ + S + + N S ++D + ++ S + S Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630 Query: 387 NPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNN 446 + + N+S S+D S + S S ++ S + + S SNS ++ Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS-SDSSSSSDSSNSSDS 689 Query: 447 GNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506 ++ S S S +DS D++N ++ S + DS+D+ N S Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS----NSSDSSD 745 Query: 507 SQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTG 566 S SD S + + S+ + D+ ++ ++ + SS S+ Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805 Query: 567 SEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQT 626 S S+ S+ SDS NS S D + S D ++ + Sbjct: 806 SSDSSDSSDSS----DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861 Query: 627 QIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSAS 686 D+ D + SD S ++ + +S D+ S + S + S S Sbjct: 862 SNSSDSS-DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920 Query: 687 TEWKDPKNTGGWNDYKNNNSSNWGGGRPD-----EKTPSSWNENPSKDQGWGGGRQPNQG 741 ++ + N+ ++ ++++S+ D + + SS + N S + Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980 Query: 742 WSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCK 801 SS + + D + +S+ +S+ S N + + +++ + D Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040 Query: 802 RSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSG 861 S +++ +S N ++S S + SNSS SS Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD--SSNSSDSSD 1098 Query: 862 PQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPR 921 ++ + + S D D + + +S N +S + Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN---------SSDSSDSSE 1149 Query: 922 EPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPAN 981 + S +S S S+ + + +S + ++SS D + +S + ++ + Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS--SDSSDS 1207 Query: 982 APNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQG 1041 + ++ +S D SD + S + + N++ S S+ S +S S Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267 Query: 1042 GKKQMKCSLKGGNNDS 1057 S G NN S Sbjct: 1268 ESDSQSKSGNGNNNGS 1283 Score = 91.7 bits (226), Expect = 6e-18 Identities = 171/945 (18%), Positives = 322/945 (34%), Gaps = 47/945 (4%) Query: 207 DTESSSENTTDNNSASNPGSEK---STLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263 D +SS +D+ +P ++ + + G TS + S +G++ K + Sbjct: 290 DHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNH 349 Query: 264 KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323 + + T E+ G + GP SG N EG KG Sbjct: 350 RESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKG------NEGKEDKG 403 Query: 324 --ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSL 381 + N Q V Q+S+ N V N+DG + + + Sbjct: 404 QHGMILGKGNVKTQGEVVNIEGPGQKSEPGNK-----VGHSNTGSDSNSDGYDSYDFDDK 458 Query: 382 NLSSPNPME----NKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTV 437 ++ +P N N S S S ++ + K GS +D+ Sbjct: 459 SMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518 Query: 438 SGQSNS-----GNNGNNGKEREDSWKGASVQKSTGS-----KNDSWDNNNRSTGGSWNFG 487 S +NS GNNGN+ ++ DS KG S + S +DS D+++ + S + Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578 Query: 488 PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547 DS+D+ + + S S SD + S + S + ++ Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD--S 636 Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTL 607 +++ ++ SS ++ S S+ S+ + SSDS +S S D + Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696 Query: 608 LSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWG 667 S D S++ + ++ + SD S ++ + NS Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756 Query: 668 DAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPS 727 D+ SN S + S S++ D N+ ND N++ S+ + + SS + N S Sbjct: 757 DSSDSSNSSDS--SDSSDSSDSSDSSNSSDSNDSSNSSDSS-------DSSNSSDSSNSS 807 Query: 728 KDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGG 787 + SS + + D + NS+ S +S G N + + Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSD-SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866 Query: 788 NASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP 847 ++ + D S NE+ +S + + + S Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926 Query: 848 PGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNV 907 + SNSS SS ++ + + + + S D D S+ +S N + Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS-DSSDSSNSSDS 985 Query: 908 NLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDD 967 + +S + N S +S S S+ + + +S + ++SS D Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045 Query: 968 TGAS-TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS 1026 + +S ++ N+ ++ ++ +S D SD + S + +++ S Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105 Query: 1027 QGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLS 1086 S+ S +S+ S ++DS + + S+ S + D+ S Sbjct: 1106 SDSSDSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164 Query: 1087 VGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDS 1131 SD D + N D +D S +S ++DS Sbjct: 1165 SSDSSDSSDSSD--SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207 Score = 85.1 bits (209), Expect = 6e-16 Identities = 171/957 (17%), Positives = 322/957 (33%), Gaps = 113/957 (11%) Query: 184 IHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGS 243 + + D++ G+ E + D ENT D + GS+ + + G + S Sbjct: 42 VSVQDELNASGTIKESGVLVHEGD-RGRQENTQDGHKGEGNGSKWAEVGGKSFST----- 95 Query: 244 QCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGL-GNWRNVSGQDRIGPGSGFSNF 302 S + E N+ W D + + T ++G+ G N++ G S N Sbjct: 96 --YSTLANEEGNIEGWNGD-------TGKAETYGHDGIHGKEENITANGIQGQVSIIDN- 145 Query: 303 NPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGR 362 GA N+N + +T Q + +AG N Sbjct: 146 -------------------AGATNRSNTNGNTDKNT-------QNGDVGDAGHN------ 173 Query: 363 EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSV 422 E + DGP+ +N+ + +EN GNTS T + K V Sbjct: 174 EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCR----NEGNTSEITPQINSKRNGTKEAEV 229 Query: 423 GSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGG 482 +G D S+ +GN E ED G + G+ DS NN++ G Sbjct: 230 TPG------TGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDS-SNNSKGQEG 282 Query: 483 SWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQK 542 + G +D +D+ G+ + E+ P G ++ N+ + + + Sbjct: 283 Q-DHGKEDDHDSSIGQNS------DSKEYYDPEGKED-------PHNEVDGDKTSKSEEN 328 Query: 543 GHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQA 602 +PE+ G+ + + + V + T + S + G P+ + Sbjct: 329 SAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNI 388 Query: 603 VLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKN 662 + + + G+ +K T ++ + P KS+ G + S N Sbjct: 389 TKEVGKGNEGKEDKGQHGMILGKGNVK--TQGEVVNIEGPGQKSEPGNKVGHSNTGSDSN 446 Query: 663 SGGWGDAPSQSNQMKSGWGELSASTEWKDPKNT--GGWNDYKNNNSSNWGGGRPDEKTPS 720 S G+ M+ DP ++ ND N+ S N R D + Sbjct: 447 SDGYDSYDFDDKSMQG-----------DDPNSSDESNGNDDANSESDNNSSSRGD----A 491 Query: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780 S+N + SKD G G S K ++ D T ++N S +G G G ++ Sbjct: 492 SYNSDESKDNGNG---------SDSKGAEDDDSDSTSDTNNSDS-----NGNGNNGNDDN 537 Query: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840 +G S +S D S +++ +S + ++ S Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597 Query: 841 GGPPPPPPGNVRPSNSSWSS----GPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAW 896 + S+SS SS ++ + + S + S S S D D + + Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657 Query: 897 GDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPN 956 NS N + + +S + N S +S S+S+ + + + + + Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717 Query: 957 ESSPGWGEMDDTGAS-TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEE 1015 S+ + D + +S ++ N+ ++ ++ NS D S+ + S + Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777 Query: 1016 EDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQT 1075 + ++ S S+ S +S++ ++ N S+ S Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837 Query: 1076 EDNPSSKMDLSVGSLSDKKFDVD-KRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDS 1131 + S D S GS SD D + + D +D S +++ ++DS Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 93.2 bits (230), Expect = 2e-18 Identities = 255/1186 (21%), Positives = 412/1186 (34%), Gaps = 190/1186 (16%) Query: 119 GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178 G G+G P + G + + + + Q SG+ S+ G + + +S +G S + Sbjct: 1236 GSGSGHSP--SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293 Query: 179 TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238 +S H GS + C + +S +++T + S+ G S + S+ Sbjct: 1294 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344 Query: 239 KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297 + G A SG + G S S +S++ +G G+ W + SG R G GS Sbjct: 1345 QSSGYGRHGAGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 1395 Query: 298 GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354 G S+ + S+W + G ++ G+ +S+ S GQ+SR ++ S ++ Sbjct: 1396 GQSSGFGHHESSSWQS---SGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 1452 Query: 355 VNFVVSGREQAQIHNTDGPKNGNTNSLNLS---SPNPMENKGMPFGMGLGNTS-----RS 406 SG Q+ H G +G + S + S + + P+G G G +S S Sbjct: 1453 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES 1512 Query: 407 TDAPSQSTGDRKTGS-----VGSWGAARGPSGTD----TVSGQSNS-------------- 443 + S G R++ S G G++ G S T + SGQS+S Sbjct: 1513 GSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1572 Query: 444 -----GNNGNNGKEREDSWKGASV---QKSTGSKND-SWDNNNRSTGGSWNFGPQDS--- 491 G++ ++G R+ S G S Q+ +GS+ S+ + +G S + G S Sbjct: 1573 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1632 Query: 492 -------NDNKWGEGNKMT-----SGVSQGEWKQPTGSDELKIGEWSGPNQPNSST---- 535 +++ G+ + + SG S G + + S + GE G + +SS Sbjct: 1633 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQH 1692 Query: 536 GAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRP 595 G+ Q + G+ Q+P GR GS +G S+ H +GS S + G R Sbjct: 1693 GSGSRQSSGHGRQGSGSGQSPSRGRH----GSGLGHSSSHGQHGSGSGRSSSRGPYESRS 1748 Query: 596 THPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIK------QDTVWDIEEVPRPEGKSDKG 649 H ++ + + S +G +Q + Q + +D +E S G Sbjct: 1749 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD-QEGSSTGQSSSHG 1807 Query: 650 TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNW 709 G S ++Q+ + G G QS S+ + + GW+ + S Sbjct: 1808 QHG--SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865 Query: 710 GGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKP 768 G SSW + G G G SS G Q+ S+S Sbjct: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGH------SSSYEQHGSRSGQSSRGEQHGSSSGS 1919 Query: 769 VSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ 828 S +G+ G + G+G + S +G+ P+ +H Sbjct: 1920 SSSYGQHGSGSRQSLGHGQHGS-----------------GSGQSPSPSRGRHGSGSGQSS 1962 Query: 829 PPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMD 888 P SG W P S S SSG + + SG+ + S Sbjct: 1963 SYGPYGSGSG-WSSSRGP-----YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2016 Query: 889 IDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWS-------KST 941 G SA G +S + +S G S S S + Sbjct: 2017 GQHG-SASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075 Query: 942 PPAPDNGTSAWGEPNESS-----PGWGEMDDTG---------ASTTGWGNTPANAPNAMK 987 +P G G SS PG GE G +S + G+ ++ + Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135 Query: 988 PNSKSMQDGWGESDGPVTGA-----RHPSWEEEEDG--------GVWNTTGSQGSASSHN 1034 S+S Q GE G +G+ +H S + G G + G GS S H Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGH- 2194 Query: 1035 SASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV-GSLSDK 1093 S+S GQ G G S P + + + Q E S GS S Sbjct: 2195 SSSHGQHG--------SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246 Query: 1094 KFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEA 1153 + G + D+ G S G SG S+Q G + Sbjct: 2247 FCSQGQHGSTSGQSSTF---DQEGSSTGQSSSHGQHGSG----------SSQSSSYGQQG 2293 Query: 1154 PCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHG 1199 S SPS S SG + S G G+G + + R G G Sbjct: 2294 SGSGQSPSRGRHGSGSGH---SSSYGQHGSGSGWSSSSGRHGSGSG 2336 Score = 91.3 bits (225), Expect = 8e-18 Identities = 182/900 (20%), Positives = 309/900 (34%), Gaps = 131/900 (14%) Query: 157 GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216 G + +Y GSG SS++G GS + K + S T Sbjct: 899 GSGQSPSYGRHGSGSGRSSSSGRH-------------GSGSGQSSGFGHKSSSGQSSGYT 945 Query: 217 DNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTE 276 + S S G S + S + S+ +SSG+ + G S S S Sbjct: 946 QHGSGS--GHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSG-------SRQSLGH 996 Query: 277 NNNGLGNWRNVS-GQDRIGPGSG-FSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSA 334 +G G+ ++ S + R G GSG S++ P + S W +S +G E+ + +SS Sbjct: 997 GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW-------SSSRGPYESGSGHSS- 1048 Query: 335 QVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGM 394 G RE +S +++G S + H G +G ++S G Sbjct: 1049 -----GLGHRESRSG-QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG--------QHGA 1094 Query: 395 PFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKERE 454 G + + + SQS+G + GS G G+ + S + +G+ Sbjct: 1095 SSGQSSSHGQHGSGS-SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1153 Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514 G+ + +S+G + ++ S+G Q S+ ++ G G+ +SG Q + Sbjct: 1154 SGQHGSGLGESSG-----FGHHESSSG-------QSSSYSQHGSGSGHSSGYGQHGSRSG 1201 Query: 515 TGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQST 574 S + G SG + G+ Q + G+ +P GR GS +G S+ Sbjct: 1202 QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRH----GSGLGHSSS 1257 Query: 575 GSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVW 634 H +GS S + G R H ++ + + S +G +Q + + Sbjct: 1258 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317 Query: 635 DIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKS----GWGELSASTEWK 690 EG S + + + + S G+G + S Q S G G S+ + Sbjct: 1318 GQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS-GHSSSYG 1376 Query: 691 DPKNTGGWNDYKNNNSSNWGGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGW 749 + GW+ + S G SSW + G G G SS Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGH------SSSYEQH 1430 Query: 750 GEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNET 809 G Q+ S+S S +G+ G + G+G + S + Sbjct: 1431 GSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGS-----------------GS 1473 Query: 810 GRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKD 869 G+ P+ +H P SG W P S SS SSG + Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSG-WSSSRGP-----YESGSSHSSGLGHRESRS 1527 Query: 870 EEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPM 929 + SG+ + S +S G S + ++ + + G Sbjct: 1528 GQSSGYGQHGSSS--------GHSSTHGQHGSTSGQSSSCGQHGASSG------------ 1567 Query: 930 TSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPN 989 +S+S + + +G G + SPG G+ + +G + + + Sbjct: 1568 --QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR--HGSGSGRSSS 1623 Query: 990 SKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 1049 S G GES G E G ++ GS S H S+ +GQ G + + S Sbjct: 1624 SGQHGSGLGESSG--------FGHHESSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS 1674 Score = 88.6 bits (218), Expect = 5e-17 Identities = 207/1001 (20%), Positives = 351/1001 (35%), Gaps = 162/1001 (16%) Query: 119 GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178 G G+G P + G + + + + Q SG+ S+ G + + +S +G S + Sbjct: 1706 GSGSGQSP--SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1763 Query: 179 TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238 +S H GS + C + +S +++T + S+ G S + S+ Sbjct: 1764 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 1814 Query: 239 KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297 + Q + SG + G S S +S++ +G G+ W + SG R G GS Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 1865 Query: 298 GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354 G S+ + S+W + G ++ G+ +S+ S GQ+SR +Q S ++ Sbjct: 1866 GQSSGFGHHESSSWQS---SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSS 1922 Query: 355 VNFVVSGREQAQIHNTDGPKNGNTNSLNLS---SPNPMENKGMPFGMGLGNTSRSTDAPS 411 SG Q+ H G +G + S + S + + P+G G G +S S Sbjct: 1923 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYES 1982 Query: 412 ----------------QSTGDRKTGSV-------GSWGAARGPS----------GTDTVS 438 QS+G + GS G G+A G S G + Sbjct: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042 Query: 439 GQSNSGNNGNNGKEREDSWKGASV---QKSTGSKND-SWDNNNRSTGGSWNFGP------ 488 GQ SG++ ++G R+ S G S Q+ +GS+ S+ + +G S + G Sbjct: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102 Query: 489 -------------QDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSST 535 Q S+ ++ G G+ +SG Q + S + G SG + Sbjct: 2103 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQH 2162 Query: 536 GAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRP 595 G+ Q + G+ +P GR GS G S+ H +GS S + G R Sbjct: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRH----GSGSGHSSSHGQHGSGSGRSSSRGPYESRS 2218 Query: 596 THPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIK------QDTVWDIEEVPRPEGKSDKG 649 H ++ + + S +G +Q + Q + +D +E S G Sbjct: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD-QEGSSTGQSSSHG 2277 Query: 650 TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNW 709 G S ++Q+ + G G QS S+ + + GW+ + S Sbjct: 2278 QHG--SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335 Query: 710 GGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKP 768 G SSW + G G G SS G Q+ S+S Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGH------SSSYEQHGSRSGQSSRGERHGSSSGS 2389 Query: 769 VSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ 828 S +G+ G + G+G + S +G+ P+ +H Sbjct: 2390 SSSYGQHGSGSRQSLGHGQHGS-----------------GSGQSPSPSRGRHGSGSGQSS 2432 Query: 829 PPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMD 888 P SG W P S S SSG + + SG+ + S Sbjct: 2433 SYSPYGSGSG-WSSSRGP-----YESGSGHSSGLGHRESRSGQSSGYGQHGSSS------ 2480 Query: 889 IDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNG 948 +S G S + ++ + + G +S+S + + +G Sbjct: 2481 --GHSSTHGQHGSTSGQSSSCGQHGASSG--------------QSSSHGQHGSGSSQSSG 2524 Query: 949 TSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGAR 1008 G + SPG G+ + +G + + +S G GES G Sbjct: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGR--HGSGSGRSSSSGQHGSGLGESSG------ 2576 Query: 1009 HPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 1049 E G ++ GS S H S+ +GQ G + + S Sbjct: 2577 --FGHHESSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS 2614 Score = 84.3 bits (207), Expect = 1e-15 Identities = 206/930 (22%), Positives = 341/930 (36%), Gaps = 109/930 (11%) Query: 162 SNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSA 221 S++++S+W +G N+ S N V GS I S+ + + +NS Sbjct: 125 SSFSHSSWSAG--ENDSYSRN---------VRGSLKPGTESI-SRRLSFQRDFSGQHNSY 172 Query: 222 SNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP-KAKSVQSSNSTTENNNG 280 S S + + G+G QC S S G N G S ++ S + S + ++G Sbjct: 173 SGQSSSYGEQNSDSHQSSGRG-QCGSGS-GQSPNYGQHGSGSGQSSSNDTHGSGSGQSSG 230 Query: 281 LGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPAL--VQEGTSRKGALETDNSNSSAQVST 338 ++ SGQ SG+S S S+ + G S +G +S SS+ Sbjct: 231 FSQHKSSSGQS-----SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285 Query: 339 VGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL--SSPNPMENKGMPF 396 G SR+ + G SG Q+ H G +G+++S S + ++G + Sbjct: 286 HGSGSRQ------SLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGH-Y 338 Query: 397 GMGLGNTS---RSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQ-SNSGNNGNNGKE 452 G G TS + QS+G K GS +++G G+ SGQ S+SG +G++ ++ Sbjct: 339 ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS--TSGQASSSGQHGSSSRQ 396 Query: 453 REDSWKGASVQKSTGSKNDSWDNNNRSTG----GSWNFGPQDSNDNKWGEGNKMTSG--V 506 + S + + + + +S G GS + S + G G +SG V Sbjct: 397 SSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYV 456 Query: 507 SQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQ---GNAQAPCWGRSSS 563 S + G E SG Q S +G H Q G Q G SSS Sbjct: 457 SGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAG-SSS 515 Query: 564 STGSEVGG--QSTG-SNHKAGSSDS-------HNSGRRSYRPTHPDCQAVLQTLLSRTDL 613 S G G QS G S H +GS S H SG R P ++ SR Sbjct: 516 SYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSS-SRGPY 574 Query: 614 DPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDK-GTEGWESAATQTKNSGGWGDAPSQ 672 + ++G G + + + G S G G S + Q+ + G G Q Sbjct: 575 ESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG--STSGQSSSCGQHGATSGQ 632 Query: 673 SNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGW 732 S+ S S+ + + G + + + S++G SS+ ++ S GW Sbjct: 633 SSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHS-------SSYGQHGS-GSGW 684 Query: 733 GGGRQPNQGWSSGKNGWGEEVDQTKNSNWES--SASKPVSGWGEGGQNEIGTWGNGGNAS 790 P+ S +G+G + ++S + S S SG+ + G G +S Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRS-------GQSS 737 Query: 791 LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGN 850 + + G S ++ + G + + +Q P S S G+ Sbjct: 738 RSEQHG-SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS 796 Query: 851 VRPSNSS---WSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNV 907 +SS + SG A+ + SG S Q S+ S+ G S + ++ Sbjct: 797 GTSCSSSCGHYESGSGQASGFGQHESG----SGQGYSQHGSASGHFSSQGRHGSTSGQSS 852 Query: 908 NLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDD 967 + +S G +S+S + +G G + SPG G+ Sbjct: 853 SSGQHDSSSG--------------QSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG- 897 Query: 968 TGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQ 1027 +G G +P+ + S G G +G H S + G + +GS Sbjct: 898 -----SGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSG 952 Query: 1028 GSAS--SHNSASWGQGGKKQMKCSLKGGNN 1055 S+S H S S GQ + + S G ++ Sbjct: 953 HSSSYEQHGSRS-GQSSRSEQHGSSSGSSS 981 Score = 84.0 bits (206), Expect = 1e-15 Identities = 191/995 (19%), Positives = 333/995 (33%), Gaps = 183/995 (18%) Query: 157 GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216 G + NY GSG SS+N T GS + + + S + Sbjct: 198 GSGQSPNYGQHGSGSGQSSSNDT-------------HGSGSGQSSGFSQHKSSSGQSSGY 244 Query: 217 DNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS----------SGNECNLGVWKSDPKAK 266 + + + S GS + +G + +S+S SG+ +LG + ++ Sbjct: 245 SQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSR 304 Query: 267 SVQ--------SSNSTTENNNGLGNWRNVS-GQDRIGPG--SGFSNFNPNSNPSAWPALV 315 S +S++ +G G+ + S G G G SGF S S+ + Sbjct: 305 QSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKH 364 Query: 316 QEGTSRKGALETDNSNSSAQVSTVGQ---TSREQQSKMENAGVNFVVSGREQAQIHNTDG 372 G+ + + + ++S Q S+ GQ +SR+ S ++ + SGR Q + Sbjct: 365 GSGSGHSSS-QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQS 423 Query: 373 PKNGNTNSLNLSSPNPMEN--------------KGMPFGMGLGNTSRSTDAPS----QST 414 P +G S + SP+ ++ G + G G+ S++ S + Sbjct: 424 PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483 Query: 415 GDRKTGSVGSWGAARGPS----------GTDTVSGQSNSGNNGNNGKEREDSWKGASVQK 464 G + G G+ G S G+ + GQ SG+ + G R S G S Sbjct: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543 Query: 465 STG------SKNDSWDNNNRSTGGSWNFGPQDS-NDNKWGEGNKMT-SGVSQGEWKQPTG 516 S G ++ S+ + +G S + GP +S + + G G++ + SG S G + + Sbjct: 544 SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSS 603 Query: 517 SDELKI-----------------GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWG 559 S G SG + + G+ +Q + G+ Q+P G Sbjct: 604 SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRG 663 Query: 560 RSSSSTG---------------------SEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHP 598 R S G V GQS+G HK+GS S + +H Sbjct: 664 RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH- 722 Query: 599 DCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAAT 658 ++G+ R G + E + Sbjct: 723 ---------------------SSGY-----------------RKHGSRSGQSSRSEQHGS 744 Query: 659 QTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKT 718 + S +G S S+Q SG G + + + G + +++ G G + Sbjct: 745 SSGLSSSYGQHGSGSHQ-SSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803 Query: 719 PSSWNENPSKDQGWGGGRQ-PNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQ 777 + + G+G QG+S + G Q ++ + +S SG + Sbjct: 804 CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS--SGQHDSSS 861 Query: 778 NEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ----PPPPQ 833 + ++G +AS + G R + +G+ P + Q P + Sbjct: 862 GQSSSYGQHESASHHASG------RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGR 915 Query: 834 PEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGT 893 +SG G G S+S SSG S +E+ +S G+ Sbjct: 916 SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGS 975 Query: 894 SAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWG 953 S+ G +SY G P+P + S +S+ P S W Sbjct: 976 SS-GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034 Query: 954 E---PNES----SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTG 1006 P ES S G G + ++G+G +++ ++ G S G Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG---- 1090 Query: 1007 ARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQG 1041 + G ++ G GS SS +S QG Sbjct: 1091 ------QHGASSGQSSSHGQHGSGSSQSSGYGRQG 1119 Score = 76.6 bits (187), Expect = 2e-13 Identities = 162/727 (22%), Positives = 271/727 (37%), Gaps = 126/727 (17%) Query: 119 GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178 G G+G P + G + + + + + Q SG+ S+ G + + +S +G S + Sbjct: 2176 GSGSGHSP--SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233 Query: 179 TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238 +S H GS + C + +S +++T + S+ G S + S+ Sbjct: 2234 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 2284 Query: 239 KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297 + Q + SG + G S S +S++ +G G+ W + SG R G GS Sbjct: 2285 QSSSYGQQGSGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 2335 Query: 298 GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354 G S+ + S+W + G ++ G+ +S+ S GQ+SR ++ S ++ Sbjct: 2336 GQSSGFGHHESSSWQS---SGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 2392 Query: 355 VNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQST 414 SG Q+ H G +G SP+P + G G G QS+ Sbjct: 2393 YGQHGSGSRQSLGHGQHGSGSGQ-------SPSPSRGR---HGSGSG----------QSS 2432 Query: 415 GDRKTGSVGSWGAARGP----SGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKN 470 GS W ++RGP SG + G S + ++G + S G S ST ++ Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS---STHGQH 2489 Query: 471 DSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530 S + S G Q S+ + G G+ +SG +Q +GS G+ G Q Sbjct: 2490 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG----RQGSGS-----GQSPGHGQ 2540 Query: 531 PNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHN--- 587 S G+ Q+P +GR S +G GS S H+ Sbjct: 2541 RGS-----------------GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 2583 Query: 588 SGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSD 647 SG+ S H ++G+GQ + E G S Sbjct: 2584 SGQSSSYSQHGSGSG----------------HSSGYGQHGSRSGQSSRGERHGSSSGSSS 2627 Query: 648 K-GTEGWESAATQTKNSGGWGDAPSQS-NQMKSGWGELSASTEWKDPKNTG-----GWND 700 G G S + Q+ G G QS ++ + G G +S+ + +G G + Sbjct: 2628 HYGQHG--SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 2685 Query: 701 YKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSN 760 + +SS +G S+++++ G G G +QG +G DQ +S Sbjct: 2686 SRLGHSSVFGQHESGSGHSSAYSQH-----GSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740 Query: 761 WESSA-------SKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQP 813 +SS+ S SG+G G G+G + S G S + +G Sbjct: 2741 GQSSSYGHRGSGSSQSSGYGRHGA------GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQ 2794 Query: 814 NSWNKQH 820 +S QH Sbjct: 2795 SSGYSQH 2801 Score = 75.5 bits (184), Expect = 4e-13 Identities = 211/1029 (20%), Positives = 355/1029 (34%), Gaps = 156/1029 (15%) Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206 ESG+ S LG + + +S +G SS+ +S + H + + C Sbjct: 575 ESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH-------GSTSGQSSSCGQHG 627 Query: 207 DTESSSENTTDNNSASNPGS---EKSTLPGSTTSNKGKGSQCQSASSGNECNLGV-WKSD 262 T S + + S S+ S ++ + G + S GS +SS + G W S Sbjct: 628 ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS- 686 Query: 263 PKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRK 322 S S + ++G G+ ++ SGQ SG+S S+ S+ G + Sbjct: 687 ----SNGPHGSVSGQSSGFGH-KSGSGQS-----SGYSQHGSGSSHSS-------GYRKH 729 Query: 323 GALETDNSNSSAQVSTVGQTSREQQS-----KMENAGVNFVVSGREQAQI-------HNT 370 G+ +S S S+ G +S Q + G SG +++ H++ Sbjct: 730 GSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSS 789 Query: 371 DGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNT----------SRSTDAPSQSTGDRKTG 420 ++G+ S + S + G G G + S S SQ +G Sbjct: 790 SHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSG 849 Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASV---QKSTGS-KNDSWDNN 476 S G SG + GQ S ++ +G+ R S G S Q+ +GS ++ S+ + Sbjct: 850 QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909 Query: 477 NRSTGGSWNFGPQDSNDNKW-GEGNKMTSGVSQGEWKQPTGSDEL--------KIGEWSG 527 +G S + G S + G G+K +SG S G + +GS + G+ S Sbjct: 910 GSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969 Query: 528 PNQPNSSTGAWDNQKGHPLPENQ---------GNAQAPCWGRSSSSTGSEVGGQSTGSNH 578 Q SS+G+ + H Q G+ Q+P R +GS G S+ + Sbjct: 970 SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS--GQSSSYGPY 1027 Query: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638 ++GS S + G H ++ ++ + S++G T + + Sbjct: 1028 RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1087 Query: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGW 698 G S + + + S G+G S S Q G G+ + + G Sbjct: 1088 SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ-SPGHGQRGSGSRQSPSYGRHGS 1146 Query: 699 NDYKNNNSSNWGGGRPDEK-----TPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEV 753 ++++S G G + SS + G G G G ++G Sbjct: 1147 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206 Query: 754 DQTKNSNWES-------SASKPVSGWGEGGQN-----EIGTWGNG------------GNA 789 ++ +S+ S S S+ SG G G G G+G G+ Sbjct: 1207 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSG 1266 Query: 790 SLASKGGWED--------------CKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPE 835 +S+G +E S A+++ G + Q Q Q E Sbjct: 1267 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1326 Query: 836 ASGSWGGPPPPPPGNVRPSNSSWSSG-PQPATPKDEEPSGWEEPSPQSISRKMDIDDGTS 894 S + R S SS SSG + + PS S S S Sbjct: 1327 GSST----GQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGS 1382 Query: 895 AW-----------GDPNSYNYKNVNLWDKN--SQGGPAPREPNLPTPMTSKSASVWSKST 941 W G + + + + W + +Q G + S+S + Sbjct: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSG-----QS 1437 Query: 942 PPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQ------- 994 +G+S+ + G G G G G+ + +P+ + S S Q Sbjct: 1438 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY 1497 Query: 995 ---DGWGESDGPV-TGARHPS--WEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKC 1048 GW S GP +G+ H S E G + G GS+S H S++ GQ G + Sbjct: 1498 GSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTSGQS 1556 Query: 1049 SLKGGNNDS 1057 S G + S Sbjct: 1557 SSCGQHGAS 1565 >gi|239757861 PREDICTED: similar to armadillo repeat containing, X-linked 4 [Homo sapiens] Length = 2382 Score = 81.6 bits (200), Expect = 6e-15 Identities = 217/974 (22%), Positives = 316/974 (32%), Gaps = 164/974 (16%) Query: 140 TGALLQSESGTAPDSTLGGAAASNYANSTW------GSGASSNNGTSPNPIHIWDKVIVD 193 TG++ + TL GA N W G+G + P + ++ Sbjct: 877 TGSVQPQAVANSHCETLPGA--KNKVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLP 934 Query: 194 GSD--MEEWPCIASKDTESSSENTTDNNSASN-PGSEKSTLPGSTTSNKGKGSQCQSASS 250 G+ ++ P + SK + E+T + S++ TLPG+ KG S S + Sbjct: 935 GAKNKVKGNPNVVSK--AGAREDTVGSTQPQVLASSQRETLPGARNKVKGN-SNVVSKAG 991 Query: 251 GNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSA 310 E +G + A S Q N GN +S + G+G ++ Sbjct: 992 AREDTMGSAQPQVVANS-QRETLPGARNKVKGNSNAISKAEA---GAGIMGSVQVQVVAS 1047 Query: 311 WPALVQEGTSRKGALETDNSNS----SAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQ 366 + V G K NSN+ A TVG Q + N+ ++ R + + Sbjct: 1048 FQGEVLPGAKNK---VRGNSNAVPKAEAGADTVGSA---QPQAVANSQSETLLGARNKVK 1101 Query: 367 IHNTDGPKNGN-TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGD----RKTGS 421 + PK G + + + P + G + S ST + D + Sbjct: 1102 GNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAE 1161 Query: 422 VGSWGAARGPSGTDTV-SGQSNSGNNGNNGKERED-----SWKGASVQKSTGSKNDS--W 473 + G SGT Q N + NG ED W Q G +S W Sbjct: 1162 AMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWIKFRFQTMDGDWENSVSW 1221 Query: 474 -DNNNRSTGGSWNFGPQDSND--NKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530 D+ N ++ GSW+ G D W TS S W + + IG W+ + Sbjct: 1222 ADDENEASIGSWS-GASDKAGIIRSWAVACDETSVKS---WAGARAENVVGIGTWARAGE 1277 Query: 531 PNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGR 590 +S G W G W +S GG TG+ ++A +G Sbjct: 1278 -QASGGLWAG----------GQTSEGTWAGDKAS-----GGAWTGAENQASGGSWALAGN 1321 Query: 591 RSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTV---WDIEEVPRPEGKSD 647 QA+ + + D G + + ++ + W E EG Sbjct: 1322 ----------QAIGELWAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWA 1371 Query: 648 KGTEG-------WESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWND 700 G W Q G W QS E AS E G W Sbjct: 1372 GAGAGNMSSVSYWAGVVDQA-GGGSWAGTSDQSGGGSKPRFEDQASGE-------GSWAG 1423 Query: 701 YKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSN 760 S G D+ + SW + + DQ GG R + SSG W +DQ+ Sbjct: 1424 AGGQASGGSMLGPEDQSSGRSWAD--TADQASGGSRLGHVDQSSG-GAWAGTLDQS---- 1476 Query: 761 WESSASKPVSGWGEGGQNEIGTW-GNGGNASLASKGGWEDCKRSPAWNETGRQPN----- 814 SKP E E G+W G GG A SK G ED +W +G Q + Sbjct: 1477 --GGGSKPRF---ENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLV 1531 Query: 815 ---------SWNKQ-HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQP 864 SW H P+ Q GSW G+ R SSG Sbjct: 1532 GIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSW 1591 Query: 865 ATPKDEEPSGW--EEPSPQSISRKMDIDDGTSAWGD-PNSYNYKNVNLWDKNSQGGPAPR 921 A D+ SGW P Q+ G G P N + WD Sbjct: 1592 AGTGDQA-SGWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWD---------- 1640 Query: 922 EPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPG--W-GEMDDTGASTTGWGNT 978 +P + S S W+ + G S G +++ G W G D TG + Sbjct: 1641 -----SPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGS------ 1689 Query: 979 PANAPNAMKPNSKSMQDG---WGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNS 1035 +P S+ G WG + G V G P ++ GG W TG+Q S Sbjct: 1690 --------RPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSS-----G 1736 Query: 1036 ASWGQGGKKQMKCS 1049 SW G + + CS Sbjct: 1737 RSWIGPGDQAVDCS 1750 Score = 74.7 bits (182), Expect = 8e-13 Identities = 211/1009 (20%), Positives = 323/1009 (32%), Gaps = 171/1009 (16%) Query: 107 RGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPD-------STLGGA 159 RG P + G P NPN GA + T P TL GA Sbjct: 917 RGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLPGA 976 Query: 160 AASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNN 219 NS S A + T + +V S E P +K +S+ + Sbjct: 977 RNKVKGNSNVVSKAGAREDTMGSA----QPQVVANSQRETLPGARNKVKGNSNAISKAEA 1032 Query: 220 SASNPGS---------EKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270 A GS + LPG+ +G + A +G + V + P+A + Sbjct: 1033 GAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADT---VGSAQPQAVANSQ 1089 Query: 271 SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALV--QEGTSRKGALETD 328 S + N + N + G G+G + SA P +V +G + GA + Sbjct: 1090 SETLLGARNKVKG--NTIAVPKAGTGAG-------TRHSAQPQIVAGSQGETLPGARDKS 1140 Query: 329 NSNSSAQVSTVGQTSREQQSKM-----ENAGVNFVVSGREQAQIH----NTDGPKNGNTN 379 S S A+ + + + +++ G + Q IH N G ++ Sbjct: 1141 MSTSEAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAA 1200 Query: 380 SLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG------------SVGSWGA 427 + + + + S S K G SV SW Sbjct: 1201 ERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAG 1260 Query: 428 ARGPS----GTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDN-NNRSTGG 482 AR + GT +G+ SG G+ E +W G K++G +W N+++GG Sbjct: 1261 ARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAG---DKASGG---AWTGAENQASGG 1314 Query: 483 SWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGE------WSGPNQPNSSTG 536 SW + W G S G W S +GE W+G +S G Sbjct: 1315 SWALAGNQAIGELWAAGQ-----ASDGSWPGGQASGVSWVGEEAIGGSWTGAEN-QASEG 1368 Query: 537 AWDNQKGHPLPENQGN-AQAPCWGRSSSSTGSEVGGQSTGSNHKAGSS-----DSHNSGR 590 +W GN + W G GG G++ ++G + SG Sbjct: 1369 SWAGA-------GAGNMSSVSYWAGVVDQAG---GGSWAGTSDQSGGGSKPRFEDQASGE 1418 Query: 591 RSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGT 650 S+ QA ++L D S W T + + V + G + GT Sbjct: 1419 GSWAGAGG--QASGGSMLGPEDQS----SGRSWADTADQASGGSRLGHVDQSSGGAWAGT 1472 Query: 651 EGWESAAT------QTKNSGGWGDAPSQSNQ-MKSGWGELSASTEWKDPKN--TGGW--N 699 + QT G W A Q+ K G + S+ W + + +GG+ Sbjct: 1473 LDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVG 1532 Query: 700 DYKNNNSSNW-GGGRPDEKTPSSWNENPSKDQG-WGGGRQPNQGWSS-GKNGWGEEVDQT 756 N +W G G P P E+ +G W R+ G S G DQ+ Sbjct: 1533 IVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLR------DQS 1586 Query: 757 KNSNWESSASKPVSGWG---EGGQNEIGTWGNGGNASLA-SKGGWEDCKRSPAWNETGRQ 812 +W + + SGW G Q G+WG + S+ G + + +W+ G Q Sbjct: 1587 SGDSWAGTGDQ-ASGWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQ 1645 Query: 813 PNS--WNKQHQQQQPPQQPPP---PQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATP 867 + W Q P Q G W G G RP + SSG Sbjct: 1646 VSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGV 1705 Query: 868 KDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPT 927 + G P P D G S G N + ++ W GP + + Sbjct: 1706 AGGQVLGGARPGPA------DQSSGGSWAGTGNQSSGRS---WI-----GPGDQAVDCSK 1751 Query: 928 PMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGW-GNTPANAP--- 983 P A G +W G G AS W G+ P N Sbjct: 1752 PEFEDQAC------------GGGSWA-------GAGSQ----ASGESWAGSRPGNEAIGG 1788 Query: 984 NAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASS 1032 + M ++ W S+ +G S+E E + G W G++ S Sbjct: 1789 SRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGS 1837 Score = 71.2 bits (173), Expect = 8e-12 Identities = 99/441 (22%), Positives = 140/441 (31%), Gaps = 76/441 (17%) Query: 647 DKGTEGWESA-ATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNN 705 + + W A A G W A Q++ G+ S T D + G W +N Sbjct: 1252 ETSVKSWAGARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQA 1311 Query: 706 SSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA 765 S ++ W + D W GG+ W GEE Sbjct: 1312 SGGSWALAGNQAIGELWAAGQASDGSWPGGQASGVSWV------GEEA------------ 1353 Query: 766 SKPVSGWGEGGQNEI--GTWGNGGNASLASKGGWE---DCKRSPAWNETGRQPNSWNKQH 820 + G G +N+ G+W G +++S W D +W T Q +K Sbjct: 1354 ---IGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGGSKPR 1410 Query: 821 QQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSP 880 + Q GSW G G SSG A D+ G Sbjct: 1411 FED---------QASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGG------ 1455 Query: 881 QSISRKMDIDDGT-SAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTS-----KSA 934 SR +D + AW S GG PR N T S A Sbjct: 1456 ---SRLGHVDQSSGGAWAGTLD-----------QSGGGSKPRFENQTTEEGSWAGAGGQA 1501 Query: 935 SVWSKSTPPAPDNGTSAWGEPNESSPGW--GEMDD-TGASTTGWGNTPANAPNAMKPNSK 991 SK P +G S ++ S G+ G +D G S TG G+ + P + + Sbjct: 1502 GGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQV 1561 Query: 992 SMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGS-------ASSHNSASWGQGGKK 1044 S + W ++ V G ++ G W TG Q S S N SWG + Sbjct: 1562 SGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASGQ 1621 Query: 1045 QMKCSLKGGNND----SWMNP 1061 + S G N SW +P Sbjct: 1622 DVGGSRPGPTNQSSAGSWDSP 1642 Score = 68.6 bits (166), Expect = 5e-11 Identities = 176/812 (21%), Positives = 286/812 (35%), Gaps = 115/812 (14%) Query: 122 AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGG--AAASNYANSTWGSGASSNNGT 179 AG T PGA + + A TA D A A + S GSG + T Sbjct: 1126 AGSQGETLPGARDKSMSTSEA-----EATAEDEAYAKPEAEAMPTSESEGGSGTQACRKT 1180 Query: 180 SPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDN---NSASNPGSEKSTLPGSTT 236 PN IH + +G +E+W IA++ T D NS S E GS + Sbjct: 1181 QPN-IHDY---YWNGIGVEDW--IAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWS 1234 Query: 237 SNKGKGSQCQS-ASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGP 295 K +S A + +E ++ W + + EN G+G W Q G Sbjct: 1235 GASDKAGIIRSWAVACDETSVKSW-----------AGARAENVVGIGTWARAGEQASGGL 1283 Query: 296 GSGFSNFN-----PNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350 +G ++ AW + + AL + + ++ GQ S Sbjct: 1284 WAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALA--GNQAIGELWAAGQASDGSWPGG 1341 Query: 351 ENAGVNFV---------VSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLG 401 + +GV++V QA + G GN +S++ + + G G G Sbjct: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGG---GSWAG 1398 Query: 402 NTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGAS 461 + +S D+ +G GSW A G + ++ G + + SW + Sbjct: 1399 TSDQSGGGSKPRFEDQASGE-GSWAGAGGQASGGSMLGPEDQSSG--------RSWADTA 1449 Query: 462 VQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELK 521 Q S GS+ D +S+GG+W G D + G S+ ++ T + Sbjct: 1450 DQASGGSRLGHVD---QSSGGAW-AGTLD-----------QSGGGSKPRFENQTTEE--- 1491 Query: 522 IGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEV-GGQSTGSNHKA 580 G W+G G PE+Q + GRS +++G ++ GG G +A Sbjct: 1492 -GSWAG-------AGGQAGGGSKVGPEDQSS------GRSWANSGDQISGGFLVGIVDQA 1537 Query: 581 GSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVP 640 +G + P + + S D +V+ ++ G W Sbjct: 1538 NGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSW------ 1591 Query: 641 RPEGKSDKGTEGWESAATQTKNSGG-WGDAPSQS-NQMKSGWGELSASTEWKDPKNTGGW 698 G D+ + GW ++ +GG WG A Q + G S++ W P + Sbjct: 1592 --AGTGDQAS-GWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSG 1648 Query: 699 NDYKNNNSSNWGGG--RP--DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754 + + + + GG +P +++ + DQ GG R ++ SSG WG Sbjct: 1649 SCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGG 1708 Query: 755 QTKNSNWESSASKPVSG-W-GEGGQNEIGTW-GNGGNASLASKGGWED-CKRSPAWNETG 810 Q A + G W G G Q+ +W G G A SK +ED +W G Sbjct: 1709 QVLGGARPGPADQSSGGSWAGTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAG 1768 Query: 811 RQPN--SW--NKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866 Q + SW ++ + + GSW G + S ++ Sbjct: 1769 SQASGESWAGSRPGNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFG 1828 Query: 867 PKDEEPSG---WEEPSPQSISRKMDIDDGTSA 895 P E G W E +SR D D+ T+A Sbjct: 1829 PGAEAVIGSWCWTEEKADIVSRPDDKDEATTA 1860 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 75.5 bits (184), Expect = 4e-13 Identities = 139/608 (22%), Positives = 228/608 (37%), Gaps = 85/608 (13%) Query: 225 GSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNW 284 GS +S+ G S G+ S Q +S ++ + + S + + G G + Sbjct: 599 GSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQY 658 Query: 285 RNVSGQDR--------IGPGSGFSNFNPNSNPSAWPALVQEGT-SRKGALETDNSNSSAQ 335 + SGQ G SGF S S++ Q G S + + + +SS Q Sbjct: 659 GSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYG---QHGFGSSQSSGYGQHGSSSGQ 715 Query: 336 VSTVGQ--TSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTN------SLNLSSPN 387 S GQ S Q S G SG Q+ G +G ++ S + S Sbjct: 716 TSGFGQHELSSGQSSSFGQHG-----SGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770 Query: 388 PMENKGMPFGMGLG-NTSRSTDAPSQ-STGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445 + G G G + SR T Q +G ++ G +G+ G S G S SG Sbjct: 771 GQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHG-SGSGQ 829 Query: 446 NGNNGKEREDSWKGASVQKSTGSKNDS-WDNNNRSTGGSWNFGPQDSNDNKW-GEGNKMT 503 + G+ S + + Q +GS S + + S+G + FG S+ ++ G G + Sbjct: 830 SSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGS 889 Query: 504 -SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSS 562 SG S G + TGS G++SG Q S + +Q + G++Q+ +G+ Sbjct: 890 GSGQSSGFGQHGTGS-----GQYSGFGQHESRS----HQSSYG-QHGSGSSQSSGYGQHG 939 Query: 563 SSTGSEVG--------GQSTG-SNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDL 613 SS+G G GQS+G H +GS S G+ ++ S+++ Sbjct: 940 SSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNY 999 Query: 614 DPR---VLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAP 670 ++G+GQ G S T G+ + + G+G Sbjct: 1000 GQHGSGSSQSSGYGQ-----------------HGSSSGQTTGFGQHRSSSGQYSGFGQHG 1042 Query: 671 SQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSN----WGGGRPDEKTPSSWNENP 726 S S+Q SG+G+ + + G+ Y++ + + G G N Sbjct: 1043 SGSDQ-SSGFGQHGTGS-----GQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNS 1096 Query: 727 SKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE----GGQNEIGT 782 + G+G R P G SSG +G Q+ S + SG+ + GQ+ G Sbjct: 1097 GQTSGFGQHR-PGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQ 1155 Query: 783 WGNGGNAS 790 G G + S Sbjct: 1156 HGTGSSQS 1163 Score = 68.9 bits (167), Expect = 4e-11 Identities = 199/949 (20%), Positives = 322/949 (33%), Gaps = 161/949 (16%) Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180 G P C P +NP + + + P + G + +S G S + + Sbjct: 332 GGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSC 391 Query: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240 N H + + + SSS N GS +ST + G Sbjct: 392 SNGQHEYGS--------------CGRFSNSSSSNEFSKCDQYGSGSSQST----SFEQHG 433 Query: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQS-----SNSTTENNNGLGNWRNVSGQDRIGP 295 G S + C G ++ S QS S++ +G G + SGQ Sbjct: 434 TGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQS---- 489 Query: 296 GSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGV 355 SGF S S+ G + G++ +S S GQ+S Q + + Sbjct: 490 -SGFGQCGSGSGQSS-------GFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQS 541 Query: 356 NFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGM-GLGNTSRSTDAPSQST 414 ++ G +G++ S E G FG GLG+ QST Sbjct: 542 SYGQHG-------------SGSSQSSGYGQYGSRETSG--FGQHGLGS--------GQST 578 Query: 415 GDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASV--QKSTGSKNDS 472 G G +G+ SG + GQ SG+ ++G + +S G S Q S+GS S Sbjct: 579 G------FGQYGSG---SGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSS 629 Query: 473 W--DNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530 + +R T G G S +G+ SG S G + +GS G+ SG Q Sbjct: 630 GYGQHGSRQTSGFGQHGSGSSQSTGFGQYGS-GSGQSSGFGQHVSGS-----GQSSGFGQ 683 Query: 531 PNSSTGAWD-NQKGHPLPENQGNAQAPCWGRSSSSTGSEVG-GQSTGSNHKAGSSDSHNS 588 S +G Q G G++Q+ +G+ SS+G G GQ S+ ++ S H S Sbjct: 684 HESRSGHSSYGQHGF------GSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGS 737 Query: 589 G--RRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKS 646 G + S H ++G+GQ + + + S Sbjct: 738 GSGQSSGFGQHGSGSG----------------QSSGFGQHESRSGQSSYGQHSSGSSQSS 781 Query: 647 DKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNS 706 G G + QT G G SQS +G+G+ + + + G+ + + + Sbjct: 782 GYGQHG----SRQTSGFGQHGSGSSQS----TGFGQYGSGSG-----QSAGFGQHGSGSG 828 Query: 707 SNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSAS 766 + G G+ + ++ S S Q G Q SSG G QT S+S Sbjct: 829 QSSGFGQHESRSHQS-----SYGQHGSGSSQ-----SSGYGQHGSSSGQTSGFGQHRSSS 878 Query: 767 KPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826 SG+G+ G G+G ++ G +E+ +S+ QH Sbjct: 879 GQYSGFGQHGS------GSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYG-QHGSGSSQ 931 Query: 827 QQPPPPQPEASGSWGGPPPPPPGNVRPS---NSSWSSGPQPATPKDEEPSGWEEPSPQSI 883 +SG G G+ + S SG + E SG Q Sbjct: 932 SSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHE 991 Query: 884 SRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPP 943 SR + G G S Y Q G + + ++ + Sbjct: 992 SRSSQSNYGQHGSGSSQSSGY---------GQHGSS----------SGQTTGFGQHRSSS 1032 Query: 944 APDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNA---MKPNSKSMQDGWGES 1000 +G G ++ S G+G+ ++G+G + + + + S G+G+ Sbjct: 1033 GQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQ- 1091 Query: 1001 DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 1049 G +G + G + G GS S S+ +GQ G K S Sbjct: 1092 HGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSG-QSSGFGQHGSGTGKSS 1139 Score = 57.8 bits (138), Expect = 1e-07 Identities = 225/1129 (19%), Positives = 383/1129 (33%), Gaps = 136/1129 (12%) Query: 145 QSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIA 204 + ES T D S Y +S+W G +G S G C Sbjct: 110 EEESETEEDEEDTPGHKSGYRHSSWSEG--EEHGYS------------SGHSRGTVKCRH 155 Query: 205 SKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264 ++ ++S + GS+K S+ + G + + SS E + KS Sbjct: 156 GSNSRRLGRQGNLSSSGNQEGSQKR-YHRSSCGHSWSGGKDRHGSSSVELRERINKSHIS 214 Query: 265 AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQE---GTSR 321 + S E+ +G +W G + G S NS S ++E G+S Sbjct: 215 PS--RESGEEYESGSGSNSWER-KGHGGLSCGLETSGHESNSTQSR----IREQKLGSSC 267 Query: 322 KGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSL 381 G+ ++ + + S R Q + F G + + I ++G + + Sbjct: 268 SGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYI------QSGCQSGI 321 Query: 382 NLSSPNPMENKGMPFGMGLGNTSRSTDAPSQ-STGDRKTGSVGSWGAA-RGPSGTDTVSG 439 + + G P G G ++ + + SQ G R+ G + G R S + G Sbjct: 322 KGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCG 381 Query: 440 QSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEG 499 Q SG + + + + G+ + S S ++ + ++ GS Q ++ + G G Sbjct: 382 QYGSGGSQSCSNGQHEY--GSCGRFSNSSSSNEFSKCDQYGSGS----SQSTSFEQHGTG 435 Query: 500 NKMTSGVSQGEWK--QPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPC 557 +SG Q Q G E + G +Q SS+G H Q + C Sbjct: 436 LSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQC 495 Query: 558 WGRSSSSTG----SEVGGQSTG-SNHKAGSSDSHNSGR---RSYRPTHPDCQAVLQTLLS 609 S S+G V GQS+G H + S S G+ RS + ++ + Sbjct: 496 GSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSG 555 Query: 610 RTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDA 669 R S G+GQ + + G+S G+ + + S G+G Sbjct: 556 YGQYGSRETS--GFGQHGLGSGQSTGFGQYGSGSGQSS----GFGQHGSGSGQSSGFGQH 609 Query: 670 PSQSNQMKSGWGELSASTEWKD------PKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWN 723 S+S Q S +G+ S+ + + T G+ + + +S + G G+ + S Sbjct: 610 ESRSGQ--SSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSG 667 Query: 724 -----ENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE---- 774 + G+G + S G++G+G Q+ S+S SG+G+ Sbjct: 668 FGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGS--SQSSGYGQHGSSSGQTSGFGQHELS 725 Query: 775 -GGQNEIGTWGNG----------GNASLASKGGWEDCKRSP----AWNETGRQPNSWNKQ 819 G + G G+G G+ S S G + RS + +G +S Q Sbjct: 726 SGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQ 785 Query: 820 HQQQQP----PQQPPPPQPEASGSWGGPPPPPPG-NVRPSNSSWSSGPQPATPKDEEPSG 874 H +Q Q G +G G S S SSG + + S Sbjct: 786 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSY 845 Query: 875 WEEPSPQSIS----RKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMT 930 + S S S + TS +G S + + S G + T Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGT--G 903 Query: 931 SKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNA----M 986 S S + + + + G + S G+G+ + T G+G + + + Sbjct: 904 SGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQ 963 Query: 987 KPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQM 1046 + G+G+ + + + + E + G GS SS S+ +GQ G Sbjct: 964 HGSGSGQSSGFGQHES--GSGKSSGFGQHESRSSQSNYGQHGSGSS-QSSGYGQHGSSSG 1020 Query: 1047 KCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGD 1106 + + G + S + Q+S G D S GS F G Sbjct: 1021 QTTGFGQHRSS-----SGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGF---------GQ 1066 Query: 1107 FNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKL 1166 + R+ G G++ S Y + + S Q G P S S Sbjct: 1067 YESRSRQSSYG-----QHGSGSSQSSGYGQHGS--NSGQTSGFGQHRPGSGQSSGFGQYG 1119 Query: 1167 SPSGSTLPNVSLGAIGTGLNPQNFAA----RQG-GSHGLFGNSTAQSRG 1210 S SG + G G+G + A R G S+G G ++QS G Sbjct: 1120 SGSGQ---SSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSG 1165 Score = 50.8 bits (120), Expect = 1e-05 Identities = 188/972 (19%), Positives = 325/972 (33%), Gaps = 127/972 (13%) Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWG---SGASSNN 177 G+G + G + +++ T Q SG+ S G + + +S +G SG+ ++ Sbjct: 926 GSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSS 985 Query: 178 GTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTS 237 G + + SS + T S+ G + S Sbjct: 986 GFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGS 1045 Query: 238 NKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGS 297 ++ G SG G ++S + S S + ++G G + SGQ S Sbjct: 1046 DQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQT-----S 1100 Query: 298 GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNF 357 GF P S S+ G + G+ +S S G++S Q + Sbjct: 1101 GFGQHRPGSGQSS-------GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYR------ 1147 Query: 358 VVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDR 417 SG+ H T G++ S FG + + + + + Sbjct: 1148 --SGQSSYGQHGT-----GSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSG 1200 Query: 418 KTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNN 477 ++ G +G+ G S T G+S +G+ R+++ G ++ +T + S + Sbjct: 1201 QSTGFGQYGSGSGQS-TGLGQGESQQVESGSTVHGRQETTHGQTI--NTTRHSQSGQGQS 1257 Query: 478 RSTGGSWNFGPQDS-NDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTG 536 TG + S ++N E + S GS K G Q G Sbjct: 1258 TQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQ-----G 1312 Query: 537 AWDNQKGHPLPE-NQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNS-GRRSYR 594 Q+G + G+ Q S+ TGS G+ S+ A S+ H+ R + Sbjct: 1313 TTHGQRGDTTRHGHSGHGQ-------STQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHS 1365 Query: 595 PTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWE 654 QA Q S + + R T +GQT G G Sbjct: 1366 QEQTHSQAGSQHGESESTVHER--HETTYGQT-------------GEATGHGHSGHGQST 1410 Query: 655 SAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRP 714 ++T G G + S +++ SG S E T G ++ S + GR Sbjct: 1411 QRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQE-----QTHGQAGSQHGESGSTVHGR- 1464 Query: 715 DEKTPSSWNENPSKDQGWGGGRQPNQGWS-SGKNGWGEEVDQTKNSNWESSASKPVSGWG 773 T + ++ + G+ +G S +G+ G G ++ +S S S SG Sbjct: 1465 -HGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGH--SESSDSEVHSGGSHTHSGHT 1521 Query: 774 EG------GQNEI-------GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQH 820 G G++E T G G+ + S G E ++ + TGRQ S ++ Sbjct: 1522 HGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGS-RTTGRQRTSHSEST 1580 Query: 821 QQQ--QPPQQPPPPQPEASGSWGGPPPPPP-----------GNVRPSNSSWSSGPQPATP 867 + P + G G P G + + SG +T Sbjct: 1581 DSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQ 1640 Query: 868 KDEEPSGWEEPSPQSISRKMDIDDGTS------AWGDPNSYNYKNVNLWDK-----NSQG 916 + +G + S S S ++ G S G S + ++ ++ + + Q Sbjct: 1641 RGSRTTG-RQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQT 1699 Query: 917 GPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWG 976 G R + +T+++ S T +G S + + S G+ +G S T G Sbjct: 1700 GDTTRHAHYHHGLTTQTGS----RTTGRRGSGHSEYSD----SEGY-----SGVSHTHSG 1746 Query: 977 NTPANAPNAMKPNSKSMQDGWGE---SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033 +T A + + + + G G T H + G TTG + S S Sbjct: 1747 HTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGS-RTTGRRSSGHSE 1805 Query: 1034 NSASWGQGGKKQ 1045 S S G G Q Sbjct: 1806 YSDSEGHSGFSQ 1817 Score = 47.0 bits (110), Expect = 2e-04 Identities = 83/418 (19%), Positives = 148/418 (35%), Gaps = 65/418 (15%) Query: 194 GSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASS--- 250 GS E I + ++ T D + S G +ST GS+T+ + + +S+ S Sbjct: 1830 GSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVH 1889 Query: 251 --GNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNP 308 G+ + G S +++ +S ++ + + + GQ G + +P+ Sbjct: 1890 SGGSHTHSGHTHSQARSQHGESESTVHKRH------QTTHGQT----GDTTEHGHPSHGQ 1939 Query: 309 SAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIH 368 + +Q G+ G + +S S G + AG ++ SG + +H Sbjct: 1940 T-----IQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESG---SSVH 1991 Query: 369 NTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG------SV 422 G +G T G +ST S++TG R +G S Sbjct: 1992 ERHGTTHGQTADTTRH--------------GHSGHGQSTQRGSRTTGRRASGHSEYSDSE 2037 Query: 423 GSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRS--T 480 G G + SG S G +G++ ER + G + + + + + R T Sbjct: 2038 GHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRT 2097 Query: 481 GGSWNFGPQDSNDNKWGEGNKMT-SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWD 539 G G +S+D++ G T SG + G+ + G I G + Sbjct: 2098 AGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRH 2157 Query: 540 NQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTH 597 Q GH G+S+ + G ++TG + S S + PTH Sbjct: 2158 GQSGH--------------GQST-----QTGSRTTGRQRSSHSESSDSEVHSEASPTH 2196 Score = 35.0 bits (79), Expect = 0.67 Identities = 88/456 (19%), Positives = 157/456 (34%), Gaps = 34/456 (7%) Query: 158 GAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTD 217 G+ S Y++S SG S + H + GS E + ++ T D Sbjct: 1952 GSGHSEYSDSEGPSGVSHTHSG-----HTHGQA---GSHYPESGSSVHERHGTTHGQTAD 2003 Query: 218 NNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTEN 277 + G +ST GS T+ G+ + S S +E + GV + Q+ + E+ Sbjct: 2004 TTRHGHSGHGQSTQRGSRTT--GRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGES 2061 Query: 278 NNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVS 337 + + +R G G + S Q G+ G + +S SS Sbjct: 2062 GSSV--------HERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEV 2113 Query: 338 TVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFG 397 G + A SG + IH G +G T ++ + G Sbjct: 2114 HSGVSHTHSGHTYGQARSQHGESG---SAIHGRQGTIHGQTGD---TTRHGQSGHGQSTQ 2167 Query: 398 MGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSW 457 G T R + S+S+ D + S S G + + S SG++G+ + Sbjct: 2168 TGSRTTGRQRSSHSESS-DSEVHSEAS-PTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQ 2225 Query: 458 KGASVQKSTGSKNDSWDNNNRSTG--GSWNFGPQDSNDNKWGEGNKM--TSGVSQGEWKQ 513 G + + + S +R+TG GS + DS + WG G + + +Q Sbjct: 2226 TGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQ 2285 Query: 514 PTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQS 573 P + ++ G + G G+ G+ + S S+ + G S Sbjct: 2286 PGSTVHGRLETTHGQTGDTTRHG----HSGYGQSTQTGSRSSRASHFQSHSSERQRHGSS 2341 Query: 574 TGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLS 609 H + ++ G Y P+ +++ + LS Sbjct: 2342 QVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLS 2377 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 69.3 bits (168), Expect = 3e-11 Identities = 162/770 (21%), Positives = 230/770 (29%), Gaps = 145/770 (18%) Query: 807 NETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866 N+ +Q +Q QQQQ Q P G+ GG P P P PQ Sbjct: 53 NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD---------MEQPQHGG 103 Query: 867 PKDEEPSGW-EEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQ---------- 915 KD G + P P +S+ D DD G+P Y++ L +Q Sbjct: 104 AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGG 163 Query: 916 GGPA--PREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973 GGPA P N S ++ P +G + SPG G M A+ Sbjct: 164 GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-------GQQSPGMGMMHSASAAAA 216 Query: 974 GWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033 G AP +M P S + G P GG GS G Sbjct: 217 G-------APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269 Query: 1034 NSASWGQG------GKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV 1087 + + G G + GG + A G+LS M + Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA----GYGVLSSPRQQGGGMM---M 322 Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147 G + K A GF+ ++ + + P +L S Sbjct: 323 GPGGGGAASLSKAAAG---------SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373 Query: 1148 CLGDEAP--CSPFSPSPSYKLSPSGSTLPNVSLG----AIGTGLNPQ----------NFA 1191 G P SP +P P S + + G A G GL +A Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433 Query: 1192 ARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLS 1251 A Q SH T + P++ R Q+ +P +P Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 Query: 1252 PGLFNVGPQLSPQQIAMLSQLP------QIPQFQLACQLLLQQ-----QQQQQLLQNQRK 1300 P GPQ P I + + P Q PQ Q+ Q Q QQ QQ +Q+ Sbjct: 494 P----PGPQRYP--IGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQP 547 Query: 1301 ISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLD-NMVPNALNVGL 1359 + Q + ++ Q QQ Q G + P G H D N++ L Sbjct: 548 QPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSL 607 Query: 1360 PDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQ------- 1412 PDL G + GTE+ S S Q Sbjct: 608 PDLS-------------------GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP 648 Query: 1413 ---EANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGS 1469 A+ H + P + GSP +GP + +P P GS Sbjct: 649 FSPHASPHLSSIPGGPSPSPVGSPVGSNQ--------SRSGPISPASIPGSQMPPQPPGS 700 Query: 1470 KSSNASWPPEFQPGVPWK----------------GIQNIDPESDPYVTPG 1503 +S ++S P Q +P + G Q P P+ +PG Sbjct: 701 QSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750 Score = 42.4 bits (98), Expect = 0.004 Identities = 123/545 (22%), Positives = 187/545 (34%), Gaps = 92/545 (16%) Query: 81 PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVT 140 P A+Y+P + R++ QQD G G P APG PN+ + Sbjct: 553 PPQAQYLPSQSQQRYQPQQD--------------MSQEGYGTRSQPPLAPG-KPNHEDLN 597 Query: 141 GALLQSE--------SGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192 L+Q E SG+ D G A + A S GS +S + ++P Sbjct: 598 --LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 655 Query: 193 DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS--- 249 S + P + + S N S S P S S +PGS + GSQ +S+S Sbjct: 656 HLSSIPGGPSPSPVGSPVGS-----NQSRSGPISPAS-IPGSQMPPQPPGSQSESSSHPA 709 Query: 250 -------------SGNECNLGVWKSDPKAKSVQSSNSTT---ENNNGLGNWRNVSGQDRI 293 +G + N + + P+ S + + + G+ +++ + Sbjct: 710 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY 769 Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENA 353 GP S + P N S PA G S + Q + Sbjct: 770 GP--QMSQYGPQGNYSRPPAY-------SGVPSASYSGPGPGMGISANNQMHGQGPSQPC 820 Query: 354 GVNFVVSGR-EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQ 412 G V GR A + N P GN +S+ SSP M +G P GMG P Sbjct: 821 GA--VPLGRMPSAGMQNRPFP--GNMSSMTPSSPG-MSQQGGP-GMG----------PPM 864 Query: 413 STGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDS 472 T +RK A + + S G+ + +S S N S Sbjct: 865 PTVNRK--------AQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSS 916 Query: 473 WDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQP 531 N ++ ++ P N + G + +S GE K P LK G+ G QP Sbjct: 917 SLMNTQAP--PYSMAPAMVNSSAASVG--LADMMSPGESKLPL---PLKADGKEEGTPQP 969 Query: 532 NSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRR 591 S + + +G P GN P SS++ S G + S G + +S + Sbjct: 970 ESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKS 1029 Query: 592 SYRPT 596 S T Sbjct: 1030 SSSTT 1034 Score = 38.5 bits (88), Expect = 0.061 Identities = 151/744 (20%), Positives = 237/744 (31%), Gaps = 123/744 (16%) Query: 708 NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767 ++GG P+ +PS+ PS+ Q G G G K+ + +A+ Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG----LGKDMGAQYAAAS 429 Query: 768 PVSGWGEGGQNEIGTWGNGGNASLASKGGWED--CKRSPAWNETGRQPNSWNKQHQQQQP 825 P + + + G G S+G D + P G P+S QP Sbjct: 430 PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS--------QP 481 Query: 826 PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISR 885 Q P P GS+G PPG R + G Q TP +G + P Q Sbjct: 482 QQSSPYP----GGSYG-----PPGPQR-----YPIGIQGRTP--GAMAGMQYPQQQM--- 522 Query: 886 KMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG---GPAPREPNLPTPMTSKSASVWSKSTP 942 P Y + V+ + + Q P+ P+LP P S + Sbjct: 523 -------------PPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQ 568 Query: 943 PAPDNGTSAWGEPNES--SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES 1000 P D +G ++ +PG +D N +P+ S+ D G Sbjct: 569 PQQDMSQEGYGTRSQPPLAPGKPNHED------------LNLIQQERPS--SLPDLSGSI 614 Query: 1001 DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWM- 1059 D TG G +T SQG S+ + + + S+ GG + S + Sbjct: 615 DDLPTGTEATLSSAVSASG---STSSQGDQSNPAQSPFSPHASPHLS-SIPGGPSPSPVG 670 Query: 1060 NPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFR 1119 +P+ S G +S S GS S+ + M + R Sbjct: 671 SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQ---R 727 Query: 1120 PPNSKDMGTTDSGPYFEKLTLP------------FSNQDGCLGDEAPCSPFSPSPSYKLS 1167 P G +GP P SN G G + S + P +Y Sbjct: 728 NPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRP 785 Query: 1168 PSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP--VQPLNSSPSLR 1225 P+ S +P+ S G G+ G+ N+ +G P PL PS Sbjct: 786 PAYSGVPSASYSGPGPGM-------------GISANNQMHGQGPSQPCGAVPLGRMPSAG 832 Query: 1226 AQ---VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLAC 1282 Q P S S+ + Q G+ P + V + A++ Q + Sbjct: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR--- 889 Query: 1283 QLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVG 1342 Q Q L+ + SQ + S + Q P M +S + VG Sbjct: 890 QGSFPGMNQSGLMASSSPYSQPMNNSS--------SLMNTQAPPYSMAPAMVNSSAASVG 941 Query: 1343 PKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSM 1402 D M P + LP L+ G G S Y G + T + M Sbjct: 942 ---LADMMSPGESKLPLP-LKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPM 997 Query: 1403 MEGLPSVATQEANMHKNGAIVAPG 1426 S+++ + ++ +I +PG Sbjct: 998 SPSSASISSFHGD--ESDSISSPG 1019 Score = 34.7 bits (78), Expect = 0.88 Identities = 46/188 (24%), Positives = 70/188 (37%), Gaps = 38/188 (20%) Query: 1313 LARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372 L + ++ QQQQQQQQ+Q + HP+ L A G PD++ P G Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPG-PDMEQ--PQHGGA 104 Query: 1373 SGFSSGGM----------------DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANM 1416 ++GG D G+ AG R++ GL ++ TQ+ Sbjct: 105 KDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG--GRYEH-----PGLGALGTQQP-- 155 Query: 1417 HKNGAIVAPGKTRGGSPYNQFDIIPGDTL------GGHTGPAGDSWLPAKSPPTNKIGSK 1470 + PG G + +F+ G GG GP D +SP + S Sbjct: 156 ----PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211 Query: 1471 SSNASWPP 1478 S+ A+ P Sbjct: 212 SAAAAGAP 219 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 69.3 bits (168), Expect = 3e-11 Identities = 162/770 (21%), Positives = 230/770 (29%), Gaps = 145/770 (18%) Query: 807 NETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866 N+ +Q +Q QQQQ Q P G+ GG P P P PQ Sbjct: 53 NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD---------MEQPQHGG 103 Query: 867 PKDEEPSGW-EEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQ---------- 915 KD G + P P +S+ D DD G+P Y++ L +Q Sbjct: 104 AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGG 163 Query: 916 GGPA--PREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973 GGPA P N S ++ P +G + SPG G M A+ Sbjct: 164 GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-------GQQSPGMGMMHSASAAAA 216 Query: 974 GWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033 G AP +M P S + G P GG GS G Sbjct: 217 G-------APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269 Query: 1034 NSASWGQG------GKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV 1087 + + G G + GG + A G+LS M + Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA----GYGVLSSPRQQGGGMM---M 322 Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147 G + K A GF+ ++ + + P +L S Sbjct: 323 GPGGGGAASLSKAAAG---------SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373 Query: 1148 CLGDEAP--CSPFSPSPSYKLSPSGSTLPNVSLG----AIGTGLNPQ----------NFA 1191 G P SP +P P S + + G A G GL +A Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433 Query: 1192 ARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLS 1251 A Q SH T + P++ R Q+ +P +P Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 Query: 1252 PGLFNVGPQLSPQQIAMLSQLP------QIPQFQLACQLLLQQ-----QQQQQLLQNQRK 1300 P GPQ P I + + P Q PQ Q+ Q Q QQ QQ +Q+ Sbjct: 494 P----PGPQRYP--IGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQP 547 Query: 1301 ISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLD-NMVPNALNVGL 1359 + Q + ++ Q QQ Q G + P G H D N++ L Sbjct: 548 QPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSL 607 Query: 1360 PDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQ------- 1412 PDL G + GTE+ S S Q Sbjct: 608 PDLS-------------------GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP 648 Query: 1413 ---EANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGS 1469 A+ H + P + GSP +GP + +P P GS Sbjct: 649 FSPHASPHLSSIPGGPSPSPVGSPVGSNQ--------SRSGPISPASIPGSQMPPQPPGS 700 Query: 1470 KSSNASWPPEFQPGVPWK----------------GIQNIDPESDPYVTPG 1503 +S ++S P Q +P + G Q P P+ +PG Sbjct: 701 QSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750 Score = 38.9 bits (89), Expect = 0.047 Identities = 153/723 (21%), Positives = 230/723 (31%), Gaps = 126/723 (17%) Query: 708 NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767 ++GG P+ +PS+ PS+ Q G G G K+ + +A+ Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG----LGKDMGAQYAAAS 429 Query: 768 PVSGWGEGGQNEIGTWGNGGNASLASKGGWED--CKRSPAWNETGRQPNSWNKQHQQQQP 825 P + + + G G S+G D + P G P+S QP Sbjct: 430 PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS--------QP 481 Query: 826 PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISR 885 Q P P GS+G PPG R + G Q TP +G + P Q Sbjct: 482 QQSSPYP----GGSYG-----PPGPQR-----YPIGIQGRTP--GAMAGMQYPQQQM--- 522 Query: 886 KMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG---GPAPREPNLPTPMTSKSASVWSKSTP 942 P Y + V+ + + Q P+ P+LP P S + Sbjct: 523 -------------PPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQ 568 Query: 943 PAPDNGTSAWGEPNES--SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES 1000 P D +G ++ +PG +D N +P+ S+ D G Sbjct: 569 PQQDMSQEGYGTRSQPPLAPGKPNHED------------LNLIQQERPS--SLPDLSGSI 614 Query: 1001 DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWM- 1059 D TG G +T SQG S+ + + + S+ GG + S + Sbjct: 615 DDLPTGTEATLSSAVSASG---STSSQGDQSNPAQSPFSPHASPHLS-SIPGGPSPSPVG 670 Query: 1060 NPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFR 1119 +P+ S G +S S GS S+ + M + R Sbjct: 671 SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQ---R 727 Query: 1120 PPNSKDMGTTDSGPYFEKLTLP------------FSNQDGCLGDEAPCSPFSPSPSYKLS 1167 P G +GP P SN G G + S + P +Y Sbjct: 728 NPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRP 785 Query: 1168 PSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP--VQPLNSSPSLR 1225 P+ S +P+ S G G+ G+ N+ +G P PL PS Sbjct: 786 PAYSGVPSASYSGPGPGM-------------GISANNQMHGQGPSQPCGAVPLGRMPSAG 832 Query: 1226 AQ---VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLAC 1282 Q P S S+ + Q G+ P + V + A++ Q + Sbjct: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR--- 889 Query: 1283 QLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVG 1342 Q Q L+ + SQ + S + Q P M +S + VG Sbjct: 890 QGSFPGMNQSGLMASSSPYSQPMNNSS--------SLMNTQAPPYSMAPAMVNSSAASVG 941 Query: 1343 PKPHLDNMVPNALNVGLP---DLQTKG-PIPGYGSGFSSGGMDYGMVGGK--EAGTESRF 1396 D M P + LP D + +G P P S SS G K E G E Sbjct: 942 ---LADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPER 998 Query: 1397 KQW 1399 K W Sbjct: 999 KLW 1001 Score = 35.0 bits (79), Expect = 0.67 Identities = 82/347 (23%), Positives = 123/347 (35%), Gaps = 66/347 (19%) Query: 81 PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVT 140 P A+Y+P + R++ QQD G G P APG PN+ + Sbjct: 553 PPQAQYLPSQSQQRYQPQQD--------------MSQEGYGTRSQPPLAPG-KPNHEDLN 597 Query: 141 GALLQSE--------SGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192 L+Q E SG+ D G A + A S GS +S + ++P Sbjct: 598 --LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 655 Query: 193 DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS--- 249 S + P + + S N S S P S S +PGS + GSQ +S+S Sbjct: 656 HLSSIPGGPSPSPVGSPVGS-----NQSRSGPISPAS-IPGSQMPPQPPGSQSESSSHPA 709 Query: 250 -------------SGNECNLGVWKSDPKAKSVQSSNSTT---ENNNGLGNWRNVSGQDRI 293 +G + N + + P+ S + + + G+ +++ + Sbjct: 710 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY 769 Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENA 353 GP S + P N S PA G S + Q + Sbjct: 770 GP--QMSQYGPQGNYSRPPAY-------SGVPSASYSGPGPGMGISANNQMHGQGPSQPC 820 Query: 354 GVNFVVSGR-EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMG 399 G V GR A + N P GN +S+ SSP M +G P GMG Sbjct: 821 GA--VPLGRMPSAGMQNRPFP--GNMSSMTPSSPG-MSQQGGP-GMG 861 Score = 34.7 bits (78), Expect = 0.88 Identities = 46/188 (24%), Positives = 70/188 (37%), Gaps = 38/188 (20%) Query: 1313 LARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372 L + ++ QQQQQQQQ+Q + HP+ L A G PD++ P G Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPG-PDMEQ--PQHGGA 104 Query: 1373 SGFSSGGM----------------DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANM 1416 ++GG D G+ AG R++ GL ++ TQ+ Sbjct: 105 KDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG--GRYEH-----PGLGALGTQQP-- 155 Query: 1417 HKNGAIVAPGKTRGGSPYNQFDIIPGDTL------GGHTGPAGDSWLPAKSPPTNKIGSK 1470 + PG G + +F+ G GG GP D +SP + S Sbjct: 156 ----PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211 Query: 1471 SSNASWPP 1478 S+ A+ P Sbjct: 212 SAAAAGAP 219 >gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] Length = 1230 Score = 67.0 bits (162), Expect = 2e-10 Identities = 105/439 (23%), Positives = 149/439 (33%), Gaps = 107/439 (24%) Query: 619 SNTGWGQ-----TQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQS 673 SN+GW I D+ W P G S GW S S W PS S Sbjct: 32 SNSGWASPSASGASIPSDSGW---ASPSASGASTPSNSGWASF------SASWASIPSDS 82 Query: 674 NQMKSGWGELSASTEWKDPKNTGGWNDYKNNNS---SNWGGGRPD---EKTPSSWNENPS 727 GW SAS W + GW + + S+ G P PS++ +PS Sbjct: 83 -----GWASPSAS--WASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFWASPS 135 Query: 728 KDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGG 787 G + GW+S W + +S W S P + W + + +G Sbjct: 136 AS---GASTPSDSGWASPSASW---ASTSSDSGWAS----PSASWTSPSASCASSSASG- 184 Query: 788 NASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP 847 AS S GW S W S SW P Sbjct: 185 -ASTPSDSGW--ASPSVFW---------------------------VSPSTSWASSPSDF 214 Query: 848 PGNVRPSNSSWSS------GPQPATPKDEEPSGWEEPSPQ--SISRKMDIDDGTSAWGDP 899 PS+S W+S P + SGW PS S S S W Sbjct: 215 GWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWAS- 273 Query: 900 NSYNYKNVN----------LWDKNSQG-GPAPREPNLPTPMTSKSASV-------WSKST 941 +S ++ ++ W +S AP + +P S+++++ +S S Sbjct: 274 SSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASG 333 Query: 942 PPAP-DNG---TSAWGEPNESSPGWGEMDDTGAST---TGWGNTPAN--APNAMKPNSKS 992 AP D+G SA G S GW +GAST +GW + A+ +P+A ++ S Sbjct: 334 ASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPS 393 Query: 993 MQDGWGESDGPVTGARHPS 1011 GW +GA PS Sbjct: 394 -DSGWASPS--ASGASMPS 409 Score = 60.1 bits (144), Expect = 2e-08 Identities = 90/411 (21%), Positives = 136/411 (33%), Gaps = 56/411 (13%) Query: 431 PSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTG-----------SKNDSWDNNNRS 479 PSG+ S ++ + +N S GAS+ +G N W S Sbjct: 15 PSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGW----AS 70 Query: 480 TGGSWNFGPQDSNDNKWGEGN-KMTSGVSQGEWKQP--TGSDELKIGEWSGPNQPNSS-- 534 SW P DS W + S S W P +G+ W+ P+ +S Sbjct: 71 FSASWASIPSDSG---WASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIP 127 Query: 535 TGAW--DNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRS 592 + W + G P + G A S+SS ++ ++ A + S SG + Sbjct: 128 SAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGAST 187 Query: 593 YRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEV----PRPEGKSDK 648 P+ + +S + S+ GW T D+ W P G S Sbjct: 188 --PSDSGWASPSVFWVSPSTSWASSPSDFGWAST--PSDSGWASSSASCISPSASGASTS 243 Query: 649 GTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGW---NDYKNNN 705 GW S S W + S G S+S W + GW + ++ Sbjct: 244 SDSGWASP------SASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASS 297 Query: 706 SSNWGGGRPD--EKTPSSWNENPSKDQGW------GGGRQPNQGWSSGKNGWGEEVDQTK 757 S++W D +PS + GW G + GW+S V T Sbjct: 298 SASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHS---ASGVSTTS 354 Query: 758 NSNWES-SASKPVSGWGEGGQNEIGTWG--NGGNASLASKGGWEDCKRSPA 805 +S W S SAS + G + +W + AS S GW S A Sbjct: 355 DSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGA 405 Score = 47.0 bits (110), Expect = 2e-04 Identities = 62/247 (25%), Positives = 94/247 (38%), Gaps = 41/247 (16%) Query: 834 PEASGSW-----GGPPPPPPGNVRPSNSSWSS--GPQPATPKDEEPSGWEEPSPQSISRK 886 P ASG+ G P G PSNS W+S + P D SGW PS S Sbjct: 39 PSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPSD---SGWASPSASWASTP 95 Query: 887 MDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPD 946 D S W P++ ++ + P+ ++P+ + S S STP Sbjct: 96 SD-----SGWASPSA---SGASIPSDSGWASPSVSGASIPSAFWA-SPSASGASTP---- 142 Query: 947 NGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPAN--APNAMKPNSKSMQDGWGESDGPV 1004 S W P+ S W + +S +GW + A+ +P+A +S + G S Sbjct: 143 -SDSGWASPSAS---WA----STSSDSGWASPSASWTSPSASCASSSAS----GASTPSD 190 Query: 1005 TGARHPSWEEEEDGGVWNTTGSQ-GSASSHNSASWGQGGKKQMKCSLKGGNNDS---WMN 1060 +G PS W ++ S G AS+ + + W + S G + S W + Sbjct: 191 SGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWAS 250 Query: 1061 PLAKQFS 1067 P A S Sbjct: 251 PSASWVS 257 Score = 44.7 bits (104), Expect = 8e-04 Identities = 94/469 (20%), Positives = 172/469 (36%), Gaps = 71/469 (15%) Query: 121 GAGPPPCTAPGAN-PNNA-----QVTGALLQSESGTAPDSTLGGAAASNYA----NSTWG 170 G+G +A GA+ P+N+ +GA + S+SG A S G + SN +++W Sbjct: 17 GSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWA 76 Query: 171 SGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKST 230 S S + SP+ W D W + + S + +D+ AS P ++ Sbjct: 77 SIPSDSGWASPSA--SWASTPSDSG----W----ASPSASGASIPSDSGWAS-PSVSGAS 125 Query: 231 LPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQ 290 +P + ++ + SG W S + + SS+S + + +W + S Sbjct: 126 IPSAFWASPSASGASTPSDSG-------WASPSASWASTSSDSGWASPS--ASWTSPSAS 176 Query: 291 DRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350 SG S P+ + A P++ S A + S G S S Sbjct: 177 CASSSASGAS--TPSDSGWASPSVFWVSPSTSWA---------SSPSDFGWASTPSDSGW 225 Query: 351 ENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAP 410 ++ + + A + G + + + ++ S+ + G ++S S D+ Sbjct: 226 ASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSS----DSGWASSSASWDSI 281 Query: 411 SQSTG-----DRKTGSVGSWGAARGPSGTD--TVSGQSNSGNNGNNGKEREDSWKGASVQ 463 + +G S SW +A SG+ +VS S +G W S Sbjct: 282 TSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSG---------WASFSAS 332 Query: 464 KSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKM-TSGVSQGEWKQPTGSDELKI 522 ++ + W +++ S G ++D+ W + S S W P+ S Sbjct: 333 GASAPSDSGWTSHSAS-------GVSTTSDSGWASPSASGASTSSDSGWASPSAS--WAS 383 Query: 523 GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGG 571 SG + P+ S A + G +P C+ + ++ TG V G Sbjct: 384 PSASGASTPSDSGWASPSASGASMPSAPSLCPGSCFPQLTARTGFTVVG 432 Score = 37.4 bits (85), Expect = 0.14 Identities = 65/303 (21%), Positives = 98/303 (32%), Gaps = 43/303 (14%) Query: 436 TVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNK 495 + SG S ++G SW S S + SW + + S S G +D+ Sbjct: 135 SASGASTPSDSG--WASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSG 192 Query: 496 WGE--------GNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547 W S S W T SD + P++S + + G P Sbjct: 193 WASPSVFWVSPSTSWASSPSDFGWAS-TPSDSGWASSSASCISPSASGASTSSDSGWASP 251 Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSH--------NSGRRSYRPTHPD 599 +A S +ST S+ G S+ ++ + +SDS S S+ D Sbjct: 252 ----SASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSD 307 Query: 600 CQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQ 659 + ++ SR LS +GW + SD G ++ Sbjct: 308 SGSSSPSV-SRAS----TLSVSGWASFSASGASA-----------PSDSGWTSHSASGVS 351 Query: 660 TKNSGGWGD--APSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEK 717 T + GW A S SGW SAS W P +G + +S G Sbjct: 352 TTSDSGWASPSASGASTSSDSGWASPSAS--WASPSASGASTPSDSGWASPSASGASMPS 409 Query: 718 TPS 720 PS Sbjct: 410 APS 412 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 66.2 bits (160), Expect = 3e-10 Identities = 70/343 (20%), Positives = 128/343 (37%), Gaps = 15/343 (4%) Query: 146 SESGTAPDSTLGGAAASNYANSTWGSGAS--SNNGTSPNPIHIWDKVIVDGSDMEEWPCI 203 SES T ++ G + A+N +ST SGAS +N+ +S D S Sbjct: 108 SESST---TSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164 Query: 204 AS---KDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWK 260 A+ T SS +T N+ +S S ST S +S G+ + S + G Sbjct: 165 ATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGT 224 Query: 261 SDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTS 320 + S SS ++T N + S G G+ ++ + ++ A A E ++ Sbjct: 225 ATNSESSTTSSGASTATN-------SESSTPSSGAGTATNSESSTTSSGAGTATNSESST 277 Query: 321 RKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNS 380 + T ++ S+ S+ T+ +S ++G N + N +++ Sbjct: 278 VSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESST 337 Query: 381 LNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQ 440 + + ++ G + S + + S T S S ++ + T + S Sbjct: 338 TSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESST 397 Query: 441 SNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGS 483 ++SG + E GAS ++ S S N + GS Sbjct: 398 TSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGS 440 Score = 58.9 bits (141), Expect = 4e-08 Identities = 83/471 (17%), Positives = 167/471 (35%), Gaps = 25/471 (5%) Query: 141 GALLQSESGTAPDSTLGGAAASNYANSTWGSGASS--NNGTSPNPIHIWDKVIVDGSDME 198 G LL E+ T + T + ++N +S SGAS+ N+G+S + I S Sbjct: 13 GLLLHLEAATNSNET---STSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTS 69 Query: 199 EWPCIASKD---TESSSENTTDNNSASN--------PGSEKSTLPGSTTSNKGKGSQCQS 247 I + T SS +T N+ S SE ST ++ S S Sbjct: 70 NGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPS 129 Query: 248 ASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSN 307 + + N + A + +S+S+T ++ + S G + ++ + + Sbjct: 130 SGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVS 189 Query: 308 PSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQI 367 A A E ++ T ++ S S T+ +S ++G + + Sbjct: 190 SRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPS 249 Query: 368 HNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGA 427 N +++ + + ++ G+ + S + S + T S S + Sbjct: 250 SGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTS 309 Query: 428 ARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFG 487 + + T++ S ++SG + E + GAS ++ S S + + GS Sbjct: 310 SGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTS 369 Query: 488 PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547 S E + ++SG S + S G + N +S+ + G Sbjct: 370 SGTSTATN-SESSTVSSGASTATTSE---SSTTSSGASTATNSESSTVSS-----GASTA 420 Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHP 598 N ++ +++++GS V +G+ G + +S + P Sbjct: 421 TNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471 Score = 38.5 bits (88), Expect = 0.061 Identities = 34/141 (24%), Positives = 57/141 (40%), Gaps = 11/141 (7%) Query: 140 TGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEE 199 +GA + S ++ S+ G + A+N +ST SGAS+ + + S Sbjct: 310 SGANTATNSDSSTTSS-GASTATNSESSTTSSGASTATNSESSTT----------SSGAS 358 Query: 200 WPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVW 259 + T SS +T N+ +S S ST S +S G+ + S + + G Sbjct: 359 TATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGAS 418 Query: 260 KSDPKAKSVQSSNSTTENNNG 280 + S SS + T N+G Sbjct: 419 TATNSESSTTSSGANTATNSG 439 Score = 35.8 bits (81), Expect = 0.39 Identities = 73/372 (19%), Positives = 127/372 (34%), Gaps = 59/372 (15%) Query: 671 SQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGG-----RPDEKTPSSWNEN 725 S+S+ SG S +T + + G + N++SS G D T SS Sbjct: 108 SESSTTSSG---ASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164 Query: 726 PSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGN 785 + + + G S+ N V ++ S +S SG +E T N Sbjct: 165 ATNSES----STTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSN 220 Query: 786 GGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845 G + S+ S A N P+S +G+ Sbjct: 221 GAGTATNSESSTTSSGASTATNSESSTPSS--------------------GAGT------ 254 Query: 846 PPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYK 905 +S+ SSG AT + IS + + T + G + N + Sbjct: 255 ----ATNSESSTTSSGAGTATNSESSTVS------SGISTVTNSESSTPSSGANTATNSE 304 Query: 906 NVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEM 965 + S G + T + S + S+S+ + T+ E + +S G Sbjct: 305 S----STTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTA 360 Query: 966 DDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTG 1025 ++G+STT G + A + +S + ES +GA + E ++T Sbjct: 361 TNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSE-------SSTV 413 Query: 1026 SQGSASSHNSAS 1037 S G++++ NS S Sbjct: 414 SSGASTATNSES 425 >gi|17017963 forkhead box P2 isoform I [Homo sapiens] Length = 715 Score = 65.9 bits (159), Expect = 4e-10 Identities = 55/137 (40%), Positives = 73/137 (53%), Gaps = 22/137 (16%) Query: 1207 QSRGLHTPV-----QPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQL 1261 Q+ GL +P +PL S+ A + PQ I+PQ +L+Q LSP L Sbjct: 69 QTSGLKSPKSSDKQRPLQVPVSV-AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---L 121 Query: 1262 SPQQIAMLSQLPQIPQF------QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLAR 1315 QQ A++ Q Q+ +F QL QLL QQQQQQQ Q Q++ Q +QQQ+QQ + Sbjct: 122 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 181 Query: 1316 MVSALQQQQQQQQRQPG 1332 QQQQQQQQ+ PG Sbjct: 182 Q----QQQQQQQQQHPG 194 Score = 31.2 bits (69), Expect = 9.7 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319 Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + + Sbjct: 177 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 235 Query: 1320 LQQQ 1323 LQ+Q Sbjct: 236 LQRQ 239 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 65.1 bits (157), Expect = 6e-10 Identities = 199/963 (20%), Positives = 333/963 (34%), Gaps = 189/963 (19%) Query: 152 PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211 P S+ GG S + S SG S + + P + D S + P AS+ T + Sbjct: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTP-----QGRSDASHGQSGPRSASRQTRNE 1547 Query: 212 SENTTDNNSASNPGSEKSTLPGSTT-SNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270 ++ + + + E ST GS+ S G+G S +S + + D + S S Sbjct: 1548 EQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDS 1607 Query: 271 ---SNSTTENNNGLGNWRNVSG--------QDRIGPG--------SGFSNFNPNSNPSAW 311 S S + N+ G ++ G +DR G SG + +S A Sbjct: 1608 ERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQA- 1666 Query: 312 PALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTD 371 + ++ S G SA ST T R Q S + N SG +Q +++ Sbjct: 1667 ASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSG---SQASDSE 1723 Query: 372 G-PKNGNTNSLNL---SSPNPMENKGMPFGMGLGNTSRS--------TDAPSQSTGDRKT 419 G + +T S++ + P+ ++ G + RS T S+S R Sbjct: 1724 GHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTG 1783 Query: 420 GSVGSWGAAR------------GPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTG 467 S G +R G DT+ G S G G E S + S Sbjct: 1784 PSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHH 1843 Query: 468 SKNDSWDNNNRSTG--GSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEW 525 S S + ++ S G GS + Q N+ + G+G++ + + S ++G+ Sbjct: 1844 SHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQG 1903 Query: 526 --SGP----NQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNH- 578 SGP NQ +S + D+Q GH + + A S+ S G + GS+H Sbjct: 1904 QSSGPRTSRNQGSSVSQDSDSQ-GHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHE 1962 Query: 579 -KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIE 637 +AG S +S R+S R ++ GQ + Sbjct: 1963 DRAGHGHSADSSRQS---------------------GTRHTESSSRGQAASSHE------ 1995 Query: 638 EVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGG 697 + +S G + G S + SG G AS+ +D + G Sbjct: 1996 -----QARSSAG-----------ERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRG- 2038 Query: 698 WNDYKNNNSSNWGGGRPDEKTPSSWNENPS--KDQGWGGGRQPNQGWSSGKNG-WGEEVD 754 Y + +S+ G D T S + + Q + G SSG++G + +V Sbjct: 2039 ---YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095 Query: 755 QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPN 814 + S S P +G +G + + AS+ G + + P + GRQ + Sbjct: 2096 THEQSESTHGQSAPSTGGRQGSHYD---QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152 Query: 815 SWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPK--DEEP 872 HQ+Q + SG G R S SG + A+ K D+E Sbjct: 2153 -----HQEQSV---------DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQ 2198 Query: 873 SGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSK 932 SG + S S S + S+W D + ++ L + GP P Sbjct: 2199 SG--DGSRHSGSHHHE----ASSWADSSRHS-----LVGQGQSSGPRTSRPR-------- 2239 Query: 933 SASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKS 992 G+S ++ S G +D+ + G+ N + + S+ Sbjct: 2240 ---------------GSSV----SQDSDSEGHSEDSERRS---GSASRNHHGSAQEQSRD 2277 Query: 993 MQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN--SASWGQGGKKQMKCSL 1050 G+RHP E+ G ++ S + +H+ ++S GQ + Sbjct: 2278 -------------GSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARS 2324 Query: 1051 KGG 1053 G Sbjct: 2325 SAG 2327 Score = 58.5 bits (140), Expect = 6e-08 Identities = 112/614 (18%), Positives = 225/614 (36%), Gaps = 92/614 (14%) Query: 210 SSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQ 269 S E + D + S +T G + +++G+ S +SAS K+ K +S Sbjct: 2152 SHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ-SGSRSASR---------KTYDKEQSGD 2201 Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329 S + +++ +W + S +G G + P ++ ++ Q+ S + +++ Sbjct: 2202 GSRHSGSHHHEASSWADSSRHSLVGQGQ---SSGPRTSRPRGSSVSQDSDSEGHSEDSER 2258 Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389 + SA + G S ++QS+ G + H+ D +G++ + S Sbjct: 2259 RSGSASRNHHG--SAQEQSR----------DGSRHPRSHHEDRAGHGHSAESSRQS---- 2302 Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNN 449 G + S+ + S+ ++ S G + D+ S S G+ + Sbjct: 2303 ---------GTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS-SRHSGIGHGQAS 2352 Query: 450 GKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGP------QDSNDNKWGEGNKMT 503 R+ +G+S +++ S+ S D++ +S GP + + G + Sbjct: 2353 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 2412 Query: 504 SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQK------------GHPLPENQG 551 S + Q + + S + G +G Q + A D+ + GHP + G Sbjct: 2413 SFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGG 2472 Query: 552 -------------------NAQAPCWGRSSSS---TGSEVGGQSTGSNHKAGSSDSHNSG 589 ++ GRS +S +GS + T ++ ++G H+ Sbjct: 2473 RQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGS 2532 Query: 590 RRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKG 649 R + D Q +++ PR N G +Q D+ E+ R G + + Sbjct: 2533 RHHEASSRADSSGHSQVGQGQSE-GPRTSRNWGSSFSQ-DSDSQGHSEDSERWSGSASRN 2590 Query: 650 TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNT----GGWNDYKNNN 705 G SA Q ++ P + ++G G + S+ ++T GG + Sbjct: 2591 HHG--SAQEQLRDG---SRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQ 2645 Query: 706 SSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA 765 + + G R S + S+ G G G+ + SG G+ + E S Sbjct: 2646 ARSSAGERHGSHHQQS--ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 2703 Query: 766 SKPVSGWGEGGQNE 779 ++ VS G+ G ++ Sbjct: 2704 TQSVSAHGQAGSHQ 2717 Score = 57.8 bits (138), Expect = 1e-07 Identities = 130/679 (19%), Positives = 238/679 (35%), Gaps = 85/679 (12%) Query: 120 GGAGPPPCTAPGANPNNAQVTGALLQSESGTA-----PDSTLGGAAASNYANSTWGSGAS 174 G GP G+ AQ + S+ G P S+ GG ++ +S SG S Sbjct: 2753 GWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS 2812 Query: 175 SNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGS 234 ++ + H + D S + AS+ T + ++ + + + E ST Sbjct: 2813 GSHHS-----HTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867 Query: 235 TTSNKGKGSQCQSASSGNECNLGVWK-SDPKAKSVQS---SNSTTENNNGLGNWRNVSGQ 290 + ++ Q + + V + SD + S S S S + N++G S Q Sbjct: 2868 SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHG-------SAQ 2920 Query: 291 DRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350 +++ GS +P S+ + G + Q S+ GQ + + Sbjct: 2921 EQLRDGSR----HPRSHQED-----RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2971 Query: 351 ENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAP 410 +AG ++ A G +G +S S + +G N S D+ Sbjct: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH----RGYSGSQASDNEGHSEDSD 3027 Query: 411 SQSTGDRKTGSVGSWG-----AARGPSGTDTVSGQSNSGNNGNNGKEREDS---WKGASV 462 +QS G GS +ARG SG SG S S + E+ +S W G S Sbjct: 3028 TQSVSAH--GQAGSHQQSHQESARGRSGE--TSGHSGSFLYQVSTHEQSESSHGWTGPST 3083 Query: 463 QKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKI 522 + GS+++ +++R + + QD+ G Sbjct: 3084 RGRQGSRHEQAQDSSRHSASQYG---QDTIRGHPGSSR---------------------- 3118 Query: 523 GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGS 582 G G + +S + + H +QG + A S +GS ++T + ++G Sbjct: 3119 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA-----SRGQSGSRSASRTTRNEEQSGD 3173 Query: 583 SDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRP 642 S H+ R TH D Q + +++ R S D+ E+ R Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRR--SRRQGSSVSQDSDSEGHSEDSERW 3231 Query: 643 EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYK 702 G + + G S Q+++ P ++ ++G G + + ++ + + Sbjct: 3232 SGSASRNHRG--SVQEQSRHG---SRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQ 3286 Query: 703 NNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNS--N 760 +S P E+ S ++ + G R WG Q +S + Sbjct: 3287 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH 3346 Query: 761 WESSASKPVSGWGEGGQNE 779 E S ++ VSG G+ G ++ Sbjct: 3347 SEESDTQSVSGHGQAGPHQ 3365 Score = 55.1 bits (131), Expect = 6e-07 Identities = 156/780 (20%), Positives = 261/780 (33%), Gaps = 110/780 (14%) Query: 152 PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211 P S+ GG S+Y SG S ++ + H + D S AS+ T + Sbjct: 2466 PGSSSGGRQGSHYEQLVDRSGHSGSHHS-----HTTSQGRSDASHGHSGSRSASRQTRND 2520 Query: 212 SENTTDN-NSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270 ++ + +S S S S S G+G +S N + SD + S S Sbjct: 2521 EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS 2580 Query: 271 ---SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327 S S + N++G S Q+++ GS +P S+ + G Sbjct: 2581 ERWSGSASRNHHG-------SAQEQLRDGSR----HPRSHQED-----RAGHGHSADSSR 2624 Query: 328 DNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPN 387 + Q S+ GQ + + +AG ++ A G +G +S S + Sbjct: 2625 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH 2684 Query: 388 PMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWG-----AARGPSG--------- 433 +G N S D+ +QS G GS +ARG SG Sbjct: 2685 ----RGYSGSQASDNEGHSEDSDTQSVSAH--GQAGSHQQSHQESARGRSGETSGHSGSF 2738 Query: 434 ---------TDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSW 484 +++ G + G G E + + S ++ + S GG Sbjct: 2739 LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQ 2798 Query: 485 NFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH 544 + + S D+ G+ + SQG G + + N+ S G+ + H Sbjct: 2799 GYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRH 2858 Query: 545 PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604 ++ + A S + G G + + + S DS + G H + Sbjct: 2859 ----HEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEG-------HSEDSERW 2907 Query: 605 QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664 SR ++ G Q Q++ + G +S T+ S Sbjct: 2908 SGSASR--------NHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSS 2959 Query: 665 GWGDAPSQSNQMKSGWGELSAS--TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSW 722 G G A S Q +S GE S + D G + +++ G R + +S Sbjct: 2960 G-GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 3018 Query: 723 NENPSKD--------QGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA---SKPVSG 771 NE S+D G G Q + S + GE + + ++ S S+ G Sbjct: 3019 NEGHSEDSDTQSVSAHGQAGSHQQSH-QESARGRSGETSGHSGSFLYQVSTHEQSESSHG 3077 Query: 772 W----GEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQ 827 W G Q + AS+ G + + P + GRQ ++ +H Sbjct: 3078 WTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQ--GYHHEH------- 3128 Query: 828 QPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPA--TPKDEEPSGWEEPSPQSISR 885 ++SG G R S SG + A T ++EE SG + S S+SR Sbjct: 3129 -----SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSG--DSSRHSVSR 3181 Score = 53.5 bits (127), Expect = 2e-06 Identities = 189/945 (20%), Positives = 323/945 (34%), Gaps = 121/945 (12%) Query: 152 PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211 P S GG S++ S SG S ++ + H + D S + AS+ T Sbjct: 1169 PGSRRGGRQGSHHEQSVDRSGHSGSHHS-----HTTSQGRSDASHGQSGSRSASRQTRKD 1223 Query: 212 SENTTDN-NSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270 ++ + +S S S S S G+ S +S ++ + SD + S S Sbjct: 1224 KQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDS 1283 Query: 271 ---SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327 S S + N++G S +++ GS F+ S + + + + G T Sbjct: 1284 ERLSGSASRNHHG-------SSREQSRDGSRHPGFHQEDRASHGHSA--DSSRQSGTHHT 1334 Query: 328 DNSNSSAQVSTVGQT---------SREQQS--KMENAGVNFVVSGREQAQIHNTDGPKNG 376 ++S+ VS+ Q SR QQS ++G+ G QA D G Sbjct: 1335 ESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI-----GHRQASSAVRDSGHRG 1389 Query: 377 N-----TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGP 431 + TNS S + ++ G S A QS G+ S Sbjct: 1390 SSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQS-GESSGRSRSFLYQVSSH 1448 Query: 432 SGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDS 491 +++ GQ+ G G E + + S ++ + S GG + S Sbjct: 1449 EQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQS 1508 Query: 492 NDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQG 551 D G + QG G + N+ S G+ + H P Sbjct: 1509 VDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPST-- 1566 Query: 552 NAQAPCWGRSSSSTGSEVG-GQSTGS--NHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLL 608 R+ SS S+VG G+S GS + + GSS S + D + + Sbjct: 1567 --------RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDR----------DSEGHSEDSE 1608 Query: 609 SRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGD 668 R++ R + Q++ +E G S E + T+ + G Sbjct: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHS---AESSRQSGTRHAETSSGGQ 1665 Query: 669 APSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWG--GGRPDEKTPSSWNENP 726 A S Q +S GE S + ++ + +SS G G R + +S +E Sbjct: 1666 AASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH 1725 Query: 727 SKD--------QGWGGGRQPN-----QGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWG 773 S++ G G Q + +G S ++G +++ +S ++ +G Sbjct: 1726 SEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPS 1785 Query: 774 EGG-QNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPP 832 GG Q + AS+ G + + P + GRQ + H +Q Sbjct: 1786 TGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGS-----HYEQ--------- 1831 Query: 833 QPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT--PKDEEPSG----------WEEPSP 880 ++SG G R S SG + + ++E+ SG E S Sbjct: 1832 SVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSR 1891 Query: 881 QSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKS 940 SR + G S+ G S N + D +SQG E + + S W +S Sbjct: 1892 ADSSRHSQVGQGQSS-GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQS 1950 Query: 941 TPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES 1000 +G+ G +E G G D+ + +G +T +++ + + + GE Sbjct: 1951 R-----DGSRHPGSHHEDRAGHGHSADS-SRQSGTRHTESSSRGQAASSHEQARSSAGER 2004 Query: 1001 DG------PVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWG 1039 G +RH + +G +G + S S S G Sbjct: 2005 HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEG 2049 Score = 50.8 bits (120), Expect = 1e-05 Identities = 157/778 (20%), Positives = 256/778 (32%), Gaps = 112/778 (14%) Query: 319 TSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG-------VNFVVSGREQAQIHNTD 371 +SR+ ++S Q ++ + +R + +G +GR QA +D Sbjct: 352 SSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSD 411 Query: 372 GPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGP 431 G++ S S EN G G + +ST R G G++ Sbjct: 412 RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ 471 Query: 432 SGT----DTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFG 487 T D+ G++ + G G E + + S ++ + S GG Sbjct: 472 VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531 Query: 488 PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547 + S + G+ + SQG G + N+ S G + H Sbjct: 532 HEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRH--- 588 Query: 548 ENQGNAQAPCWGRSSSSTGSEVG-GQSTG--SNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604 ++ ++QA SS S+VG GQS+G ++ GSS S +S + H + Sbjct: 589 -HEASSQA------DSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG----HSEDSERW 637 Query: 605 QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664 SR ++ G Q Q + + G +S T+NS Sbjct: 638 SGSASR--------NHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSS 689 Query: 665 GWGDAPSQSNQMKSGWGELSAS---TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSS 721 G A S Q +S GE S + D G + +++ G R + ++ Sbjct: 690 S-GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQAT 748 Query: 722 WNENPSKD------QGWG-GGRQPNQGWSSGKNGWGE----------EVDQTKNSNWESS 764 +E S+D G G G S ++ GE +V K S Sbjct: 749 DSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG 808 Query: 765 ASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQ 824 + P +G +G +E + AS+ G + + P + GRQ H+Q Sbjct: 809 WTGPSTGVRQGSHHE---QARDNSRHSASQDGQDTIRGHPGSSRRGRQ----GSHHEQ-- 859 Query: 825 PPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPA--TPKDEEPS--------- 873 + SG G R S SG + A T ++EE S Sbjct: 860 --------SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGS 911 Query: 874 -GWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSK 932 E S ISR G S G S + D +S+G E + + Sbjct: 912 RHHEASSHADISRHSQAGQGQSE-GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 970 Query: 933 SASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKS 992 S +S +G+ +E G G D+ + TP +A + + S Sbjct: 971 RGSAQEQSR-----HGSRHPRSHHEDRAGHGHSADSSRQS----GTP-HAETSSGGQAAS 1020 Query: 993 MQDGWGESDGPVTGARHPSWEEE---------------EDGGVWNTTGSQGSASSHNS 1035 + S G G+RH + D G W ++GSQ S S +S Sbjct: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHS 1078 Score = 48.1 bits (113), Expect = 8e-05 Identities = 153/793 (19%), Positives = 272/793 (34%), Gaps = 119/793 (15%) Query: 196 DMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPG---STTSNKGKGSQCQSASSGN 252 D E W AS++ S + + + S +P S G S ++ G++ SSG Sbjct: 3227 DSERWSGSASRNHRGSVQEQSRHGSR-HPRSHHEDRAGHGHSADRSRQSGTRHAETSSGG 3285 Query: 253 ECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWP 312 + A S + + S+ +G + ++ G G ++ + + W Sbjct: 3286 QA----------ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQAS-SAVRDSRHWG 3334 Query: 313 ALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDG 372 + + + +G E ++ S VS GQ QQS E+A + G Sbjct: 3335 SSGSQASDSEGHSEESDTQS---VSGHGQAGPHQQSHQESA--------------RDRSG 3377 Query: 373 PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSR------------STDAPSQSTGDRKTG 420 ++G + S L + E G +T R S + SQ D G Sbjct: 3378 GRSGRSGSF-LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRG 3436 Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNN-----GKEREDSWKGASVQKSTGSKNDSWDN 475 GS + RG G+ SG++G++ + R D+ +G S +S + + + Sbjct: 3437 HPGS--SRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQ 3494 Query: 476 NNRSTGGSWNFGPQ------DSNDNKWGEG--------NKMTSGVSQGEWKQPTGSDELK 521 + + SW+ + S ++ G+G S VSQ Q D + Sbjct: 3495 SGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSER 3554 Query: 522 IGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSSSTG-----SEVGGQS 573 WSG N A + + HP ++ A SS +G + GGQ+ Sbjct: 3555 ---WSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 3611 Query: 574 TGSNHKAGSSDSHNSGRRSYRPT---------HPDCQAVLQTLLSRTDLDPRVLSNTGWG 624 S+ +A SS G + H + ++ R + + G Sbjct: 3612 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHS 3671 Query: 625 QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684 + Q + P + + T G +A ++ SG + S Q +S G Sbjct: 3672 EDSDTQSVSAHGQAGPHQQSHQE-STRG--RSAGRSGRSGSFLYQVSTHEQSESAHGRAG 3728 Query: 685 ASTEWKDPKNTGGWNDYKNNNSSNWG----GGRPDEK---TPSSWNENPSKDQGWGGGR- 736 ST + D +++S G G P + S++E G G Sbjct: 3729 PSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHH 3788 Query: 737 -----QPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASL 791 Q S G++G +T+N S+ SG +E T + S Sbjct: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRH-SG---SRHHEASTQADSSRHSQ 3844 Query: 792 ASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGP--PPPPPG 849 + +G +RS RQ +S ++ + P+ AS + G G Sbjct: 3845 SGQGESAGSRRS------RRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG 3898 Query: 850 NVRPSNS--SWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDP---NSYNY 904 + P +S +S Q + + + + E S+S+ G + G P +SY+Y Sbjct: 3899 SRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHY 3958 Query: 905 KNVNLWDKNSQGG 917 ++ + Q G Sbjct: 3959 QSEGTERQKGQSG 3971 Score = 47.8 bits (112), Expect = 1e-04 Identities = 180/908 (19%), Positives = 305/908 (33%), Gaps = 116/908 (12%) Query: 210 SSSENTTDNNSASNPGSEKSTLPGSTTSNKGK-GSQCQSASSGNECNLGVWKSDPKAKSV 268 S E + D + S +T G + +++G+ GS+ S ++ NE ++ Sbjct: 855 SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHH 914 Query: 269 Q-SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327 + SS++ ++ G ++ + GS S + + S E + R + Sbjct: 915 EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHS-------EDSERWSGSAS 967 Query: 328 DNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNT-NSLNLSSP 386 N SAQ + + + + AG Q+ + + G +S + Sbjct: 968 RNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARS 1027 Query: 387 NPMENKGMPFGMGLGNTSRSTDAPSQ--STGDRKTGSVGSWGAARGPS-------GTDTV 437 +P E G ++SR + P + S+ R +G GS G+ S T +V Sbjct: 1028 SPGERHGSRHQQS-ADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSV 1086 Query: 438 SGQSNSGNNGNNGKEREDSWKGAS--------VQKSTGSKNDSWDNNNR-STG---GSWN 485 SG G + + +E W G Q ST +++S R STG GS + Sbjct: 1087 SGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHH 1146 Query: 486 FGPQDSNDNKWGEGNKMT-----------------------SGVSQGEWKQPTGSDELKI 522 +DS+ + + + T SG S T Sbjct: 1147 EQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA 1206 Query: 523 GEWSGPNQPNSSTGAWDNQKGH-PLPENQGNAQAPCWGRSS--SSTGSEVGGQSTGSNHK 579 ++ S D Q G + +A W SS S G E S S H+ Sbjct: 1207 SHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQ 1266 Query: 580 AGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDL-DPRVLSNTGWGQTQIKQDTVWDIEE 638 S + R H D L SR R S G Q+ Sbjct: 1267 GSSVSQDSDSER-----HSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQED--RASH 1319 Query: 639 VPRPEGKSDKGTEGWESAA--------TQTKNSGG--WGDAPSQS--NQMKSGWGELSAS 686 + GT ES++ Q ++S G G QS + SG G AS Sbjct: 1320 GHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQAS 1379 Query: 687 TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGK 746 + +D + G N+ + D ++ S+ + Q + G SSG+ Sbjct: 1380 SAVRDSGHRGSSGSQVTNSEGH--SEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437 Query: 747 N-GWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPA 805 + + +V + S + P +G +G ++E + AS+ G + + P Sbjct: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHE---QARNSSRHSASQDGQDTIRGHPG 1494 Query: 806 WNETGRQPNSWNKQ------HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWS 859 + GRQ S+++Q H P + +AS GP R ++ Sbjct: 1495 SSRGGRQ-GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGP--------RSASRQTR 1545 Query: 860 SGPQPATPKDEEPSGWEEPSPQS-ISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGP 918 + Q S EPS ++ SR + G SA G S + D++S+G Sbjct: 1546 NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESA-GSKTSRRQGSSVSQDRDSEGHS 1604 Query: 919 APREPNLPTPMTSKSASVWSKS-----TPPAPDNGTSAWGEPNESS--PGWGEMDDTGAS 971 E + + S +S P + ++ G ESS G + + Sbjct: 1605 EDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGG 1664 Query: 972 TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSAS 1031 A + + S+ Q +D TG R +D V +G++GS+ Sbjct: 1665 QAASSQEQARSSPGERHGSRHQQSADSSTDSG-TGRR-------QDSSVVGDSGNRGSSG 1716 Query: 1032 SHNSASWG 1039 S S S G Sbjct: 1717 SQASDSEG 1724 Score = 43.9 bits (102), Expect = 0.001 Identities = 95/512 (18%), Positives = 164/512 (32%), Gaps = 76/512 (14%) Query: 204 ASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263 ++ + S T N+S+ S S G Q QSA S G Sbjct: 673 SADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG------ 726 Query: 264 KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323 Q+S++ ++ + R SG + T +G Sbjct: 727 ---HGQASSAVRDSGH-----RGSSG--------------------------SQATDSEG 752 Query: 324 ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL 383 E ++ S VS GQ QQS E+A R + +S Sbjct: 753 HSEDSDTQS---VSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGW 809 Query: 384 SSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNS 443 + P+ +G N+ S Q T GS + RG G+ S Sbjct: 810 TGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGS-----SRRGRQGSHHEQSVDRS 864 Query: 444 GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMT 503 G++G++ + + + +GS++ S N + S D G++ Sbjct: 865 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE----------EQSRDGSRHSGSRHH 914 Query: 504 SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSS 563 S + + + + + + + SS + +GH + + A R S+ Sbjct: 915 EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSA 974 Query: 564 STGSEVGGQSTGSNH--KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNT 621 S G + S+H +AG S +S R+S P H + + Q S Sbjct: 975 QEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTP-HAETSSGGQAASSHEQARSSPGERH 1033 Query: 622 GWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWG 681 G Q + +PR A++ ++SG WG + SQ++ G Sbjct: 1034 GSRHQQSADSS--RHSGIPR------------RQASSAVRDSGHWGSSGSQASD-SEGHS 1078 Query: 682 ELSASTEWKDPKNTGGWNDYKNNNSSNWGGGR 713 E S + G ++ +W GGR Sbjct: 1079 EESDTQSVSGHGQDGPHQQSHQESARDWSGGR 1110 >gi|149999352 forkhead box P2 isoform II [Homo sapiens] Length = 740 Score = 64.3 bits (155), Expect = 1e-09 Identities = 48/113 (42%), Positives = 62/113 (54%), Gaps = 16/113 (14%) Query: 1226 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------Q 1279 A + PQ I+PQ +L+Q LSP L QQ A++ Q Q+ +F Q Sbjct: 117 AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQ 170 Query: 1280 LACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 1332 L QLL QQQQQQQ Q Q++ Q +QQQ+QQ + QQQQQQQQ+ PG Sbjct: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 219 Score = 43.5 bits (101), Expect = 0.002 Identities = 56/189 (29%), Positives = 70/189 (37%), Gaps = 25/189 (13%) Query: 1159 SPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPL 1218 SP S K P LP L G ++ G H F + + + P Sbjct: 75 SPKSSDKQRPLQELLPETKLCICG-------HSSGDGHPHNTFAVPVSVAMMTPQVITPQ 127 Query: 1219 NSSPSLRAQV--PPQF--ISPQVSASMLKQ-----FPNSGLSPGLFNVGPQLSPQQIAML 1269 L+ QV P Q + Q A ML+Q F + Q QQ Sbjct: 128 QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQ 187 Query: 1270 SQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA---------L 1320 Q Q Q Q Q QQQQQQQ Q Q QA QQQ+QQ + ++A L Sbjct: 188 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 247 Query: 1321 QQQQQQQQR 1329 Q QQ QQQ+ Sbjct: 248 QMQQLQQQQ 256 Score = 31.2 bits (69), Expect = 9.7 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319 Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + + Sbjct: 202 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 260 Query: 1320 LQQQ 1323 LQ+Q Sbjct: 261 LQRQ 264 >gi|22538413 forkhead box P2 isoform III [Homo sapiens] Length = 623 Score = 62.8 bits (151), Expect = 3e-09 Identities = 47/109 (43%), Positives = 60/109 (55%), Gaps = 16/109 (14%) Query: 1230 PQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------QLACQ 1283 PQ I+PQ +L+Q LSP L QQ A++ Q Q+ +F QL Q Sbjct: 4 PQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 57 Query: 1284 LLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 1332 LL QQQQQQQ Q Q++ Q +QQQ+QQ + QQQQQQQQ+ PG Sbjct: 58 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 102 Score = 41.6 bits (96), Expect = 0.007 Identities = 32/79 (40%), Positives = 37/79 (46%), Gaps = 9/79 (11%) Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319 Q QQ Q Q Q Q Q QQQQQQQ Q Q QA QQQ+QQ + ++A Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120 Query: 1320 ---------LQQQQQQQQR 1329 LQ QQ QQQ+ Sbjct: 121 QQLVFQQQLLQMQQLQQQQ 139 Score = 31.2 bits (69), Expect = 9.7 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319 Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + + Sbjct: 85 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 143 Query: 1320 LQQQ 1323 LQ+Q Sbjct: 144 LQRQ 147 >gi|11761629 fibrinogen, alpha polypeptide isoform alpha preproprotein [Homo sapiens] Length = 644 Score = 62.8 bits (151), Expect = 3e-09 Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%) Query: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458 G+TS T + ++S R S GSW + + GP T G N G++G G +WK Sbjct: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323 Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518 G+S STGS W++ + TG + N P S G W P S+ Sbjct: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366 Query: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567 G W+ + + STG W ++ G P++ G+ A P WG +G+ Sbjct: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419 Score = 53.1 bits (126), Expect = 2e-06 Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%) Query: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517 +G S TGS+ +S N S+ GSWN G S G N +SG +P S Sbjct: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326 Query: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568 G W N +S TG+ NQ G P P + G W SS GS Sbjct: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378 Query: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599 V G STG H ++GS + G + RP +PD Sbjct: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409 Score = 40.8 bits (94), Expect = 0.012 Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 16/127 (12%) Query: 734 GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLAS 793 GG + +G S+ G G E + +N + S + SG G G G+ G GG A+ Sbjct: 265 GGNEITRGGSTSY-GTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-- 321 Query: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP 853 K G + +WN S Q+ P P+P ++G+W P + R Sbjct: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQN--------PGSPRPGSTGTWN-----PGSSERG 368 Query: 854 SNSSWSS 860 S W+S Sbjct: 369 SAGHWTS 375 Score = 37.0 bits (84), Expect = 0.18 Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%) Query: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696 G + GT + ++G W P + G + WK P +TG Sbjct: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332 Query: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753 WN + S N G P + +W NP + G ++ SG G W E Sbjct: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390 Query: 754 DQTKNSNWESSASKPVS-GWG 773 + + S ++P + WG Sbjct: 391 GSFRPDSPGSGNARPNNPDWG 411 Score = 36.6 bits (83), Expect = 0.23 Identities = 47/206 (22%), Positives = 76/206 (36%), Gaps = 41/206 (19%) Query: 345 EQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTS 404 + + ++E G N + G G + T S S NP G ++ Sbjct: 256 QMRMELERPGGNEITRG----------GSTSYGTGSETESPRNPSSAGSWNSGSSGPGST 305 Query: 405 RSTDAPSQSTGDRKT--------GSVGSWGAARGPSGTDTVS---------GQSNSGNNG 447 + + S TG T GS GSW + G SGT + G + + N G Sbjct: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNS--GSSGTGSTGNQNPGSPRPGSTGTWNPG 363 Query: 448 NNGKEREDSWKG-ASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506 ++ + W +SV STG + + + GS N P N+ WG +++ V Sbjct: 364 SSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARP---NNPDWGTFEEVSGNV 420 Query: 507 SQGEWKQ--------PTGSDELKIGE 524 S G ++ G EL+ G+ Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGK 446 Score = 35.8 bits (81), Expect = 0.39 Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%) Query: 1527 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1586 TGS + + S G+W +S T + + +TW P G T N Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336 Query: 1587 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1643 S T PG P + W+ S+ S W ++ S S W S+ GS Sbjct: 337 ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392 Query: 1644 VRP 1646 RP Sbjct: 393 FRP 395 Score = 34.7 bits (78), Expect = 0.88 Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%) Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329 S + N + G+W + S GPGS N NP S+ + A + G+S G+ + N Sbjct: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335 Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389 S SS ST Q N P+ G+T + N P Sbjct: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365 Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445 E + S ST +G + S GS G AR P+ D + + SGN Sbjct: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419 Score = 33.9 bits (76), Expect = 1.5 Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%) Query: 89 REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146 ++VPP ++ D + + P + + GG G T NP++A G+ Sbjct: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298 Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206 SG ++ +TW G+S T S Sbjct: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334 Query: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264 ++ SS +T N + + PGS + PGS+ +S+ SG + G W S+ Sbjct: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391 Query: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297 + S S + NN G + VSG + PG+ Sbjct: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424 Score = 32.7 bits (73), Expect = 3.3 Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 32/168 (19%) Query: 808 ETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP-SNSSWSSGPQPAT 866 E+ R P+S + P P +SG+ GG PG+ P S SW+SG Sbjct: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGT-GGTATWKPGSSGPGSTGSWNSGSSGTG 342 Query: 867 PKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLP 926 + G P P S T W +P S + W S Sbjct: 343 STGNQNPG--SPRPGS----------TGTW-NPGSSERGSAGHWTSESS----------- 378 Query: 927 TPMTSKSASVW-SKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973 S S W S+S PD+ S PN +P WG ++ + + Sbjct: 379 ---VSGSTGQWHSESGSFRPDSPGSGNARPN--NPDWGTFEEVSGNVS 421 Score = 32.7 bits (73), Expect = 3.3 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 21/123 (17%) Query: 919 APREPNLPTPMTSKSA---SVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGW 975 +PR P+ S S+ S +++ + GT+ W +P S PG ++G+S G Sbjct: 285 SPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-KPGSSGPGSTGSWNSGSS--GT 341 Query: 976 GNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS-QGSASSHN 1034 G+T P + +P S TG +P E G W + S GS + Sbjct: 342 GSTGNQNPGSPRPGS--------------TGTWNPGSSERGSAGHWTSESSVSGSTGQWH 387 Query: 1035 SAS 1037 S S Sbjct: 388 SES 390 >gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preproprotein [Homo sapiens] Length = 866 Score = 62.8 bits (151), Expect = 3e-09 Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%) Query: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458 G+TS T + ++S R S GSW + + GP T G N G++G G +WK Sbjct: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323 Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518 G+S STGS W++ + TG + N P S G W P S+ Sbjct: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366 Query: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567 G W+ + + STG W ++ G P++ G+ A P WG +G+ Sbjct: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419 Score = 53.1 bits (126), Expect = 2e-06 Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%) Query: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517 +G S TGS+ +S N S+ GSWN G S G N +SG +P S Sbjct: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326 Query: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568 G W N +S TG+ NQ G P P + G W SS GS Sbjct: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378 Query: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599 V G STG H ++GS + G + RP +PD Sbjct: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409 Score = 40.8 bits (94), Expect = 0.012 Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 16/127 (12%) Query: 734 GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLAS 793 GG + +G S+ G G E + +N + S + SG G G G+ G GG A+ Sbjct: 265 GGNEITRGGSTSY-GTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-- 321 Query: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP 853 K G + +WN S Q+ P P+P ++G+W P + R Sbjct: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQN--------PGSPRPGSTGTWN-----PGSSERG 368 Query: 854 SNSSWSS 860 S W+S Sbjct: 369 SAGHWTS 375 Score = 37.0 bits (84), Expect = 0.18 Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%) Query: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696 G + GT + ++G W P + G + WK P +TG Sbjct: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332 Query: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753 WN + S N G P + +W NP + G ++ SG G W E Sbjct: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390 Query: 754 DQTKNSNWESSASKPVS-GWG 773 + + S ++P + WG Sbjct: 391 GSFRPDSPGSGNARPNNPDWG 411 Score = 36.6 bits (83), Expect = 0.23 Identities = 47/206 (22%), Positives = 76/206 (36%), Gaps = 41/206 (19%) Query: 345 EQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTS 404 + + ++E G N + G G + T S S NP G ++ Sbjct: 256 QMRMELERPGGNEITRG----------GSTSYGTGSETESPRNPSSAGSWNSGSSGPGST 305 Query: 405 RSTDAPSQSTGDRKT--------GSVGSWGAARGPSGTDTVS---------GQSNSGNNG 447 + + S TG T GS GSW + G SGT + G + + N G Sbjct: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNS--GSSGTGSTGNQNPGSPRPGSTGTWNPG 363 Query: 448 NNGKEREDSWKG-ASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506 ++ + W +SV STG + + + GS N P N+ WG +++ V Sbjct: 364 SSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARP---NNPDWGTFEEVSGNV 420 Query: 507 SQGEWKQ--------PTGSDELKIGE 524 S G ++ G EL+ G+ Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGK 446 Score = 35.8 bits (81), Expect = 0.39 Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%) Query: 1527 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1586 TGS + + S G+W +S T + + +TW P G T N Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336 Query: 1587 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1643 S T PG P + W+ S+ S W ++ S S W S+ GS Sbjct: 337 ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392 Query: 1644 VRP 1646 RP Sbjct: 393 FRP 395 Score = 34.7 bits (78), Expect = 0.88 Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%) Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329 S + N + G+W + S GPGS N NP S+ + A + G+S G+ + N Sbjct: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335 Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389 S SS ST Q N P+ G+T + N P Sbjct: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365 Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445 E + S ST +G + S GS G AR P+ D + + SGN Sbjct: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419 Score = 33.9 bits (76), Expect = 1.5 Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%) Query: 89 REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146 ++VPP ++ D + + P + + GG G T NP++A G+ Sbjct: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298 Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206 SG ++ +TW G+S T S Sbjct: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334 Query: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264 ++ SS +T N + + PGS + PGS+ +S+ SG + G W S+ Sbjct: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391 Query: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297 + S S + NN G + VSG + PG+ Sbjct: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424 Score = 32.7 bits (73), Expect = 3.3 Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 32/168 (19%) Query: 808 ETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP-SNSSWSSGPQPAT 866 E+ R P+S + P P +SG+ GG PG+ P S SW+SG Sbjct: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGT-GGTATWKPGSSGPGSTGSWNSGSSGTG 342 Query: 867 PKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLP 926 + G P P S T W +P S + W S Sbjct: 343 STGNQNPG--SPRPGS----------TGTW-NPGSSERGSAGHWTSESS----------- 378 Query: 927 TPMTSKSASVW-SKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973 S S W S+S PD+ S PN +P WG ++ + + Sbjct: 379 ---VSGSTGQWHSESGSFRPDSPGSGNARPN--NPDWGTFEEVSGNVS 421 Score = 32.7 bits (73), Expect = 3.3 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 21/123 (17%) Query: 919 APREPNLPTPMTSKSA---SVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGW 975 +PR P+ S S+ S +++ + GT+ W +P S PG ++G+S G Sbjct: 285 SPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-KPGSSGPGSTGSWNSGSS--GT 341 Query: 976 GNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS-QGSASSHN 1034 G+T P + +P S TG +P E G W + S GS + Sbjct: 342 GSTGNQNPGSPRPGS--------------TGTWNPGSSERGSAGHWTSESSVSGSTGQWH 387 Query: 1035 SAS 1037 S S Sbjct: 388 SES 390 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 62.0 bits (149), Expect = 5e-09 Identities = 160/783 (20%), Positives = 230/783 (29%), Gaps = 158/783 (20%) Query: 807 NETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866 N+ +Q +Q QQQQ Q P G+ GG P P P PQ Sbjct: 53 NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD---------MEQPQHGG 103 Query: 867 PKDEEPSGW-EEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQ---------- 915 KD G + P P +S+ D DD G+P Y++ L +Q Sbjct: 104 AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGG 163 Query: 916 GGPA--PREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973 GGPA P N S ++ P +G + SPG G M A+ Sbjct: 164 GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-------GQQSPGMGMMHSASAAAA 216 Query: 974 GWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033 G AP +M P S + G P GG GS G Sbjct: 217 G-------APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269 Query: 1034 NSASWGQG------GKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV 1087 + + G G + GG + A G+LS M + Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA----GYGVLSSPRQQGGGMM---M 322 Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147 G + K A GF+ ++ + + P +L S Sbjct: 323 GPGGGGAASLSKAAAG---------SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373 Query: 1148 CLGDEAP--CSPFSPSPSYKLSPSGSTLPNVSLG----AIGTGLNPQ----------NFA 1191 G P SP +P P S + + G A G GL +A Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433 Query: 1192 ARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLS 1251 A Q SH T + P++ R Q+ +P +P Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493 Query: 1252 PGLFNVGPQLSPQQIAMLSQLP------QIPQFQLACQLLLQQ----------------- 1288 P GPQ P I + + P Q PQ Q + ++ Sbjct: 494 P----PGPQRYP--IGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGY 547 Query: 1289 -QQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHL 1347 QQ QQ +Q+ + Q + ++ Q QQ Q G + P G H Sbjct: 548 CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 607 Query: 1348 D-NMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGL 1406 D N++ LPDL G + GTE+ S Sbjct: 608 DLNLIQQERPSSLPDLS-------------------GSIDDLPTGTEATLSSAVSASGST 648 Query: 1407 PSVATQ----------EANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSW 1456 S Q A+ H + P + GSP +GP + Sbjct: 649 SSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ--------SRSGPISPAS 700 Query: 1457 LPAKSPPTNKIGSKSSNASWPPEFQPGVPWK----------------GIQNIDPESDPYV 1500 +P P GS+S ++S P Q +P + G Q P P+ Sbjct: 701 IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 Query: 1501 TPG 1503 +PG Sbjct: 761 SPG 763 Score = 45.8 bits (107), Expect = 4e-04 Identities = 151/724 (20%), Positives = 232/724 (32%), Gaps = 115/724 (15%) Query: 708 NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767 ++GG P+ +PS+ PS+ Q G G G K+ + +A+ Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG----LGKDMGAQYAAAS 429 Query: 768 PVSGWGEGGQNEIGTWGNGGNASLASKGGWED--CKRSPAWNETGRQPNSWNKQHQQQQP 825 P + + + G G S+G D + P G P+S QP Sbjct: 430 PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS--------QP 481 Query: 826 PQQPPPPQPEASGSWGGPPPPP-PGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSIS 884 Q P P GS+G P P P ++ +G Q +D + W+E Sbjct: 482 QQSSPYP----GGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKE------- 530 Query: 885 RKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG---GPAPREPNLPTPMTSKSASVWSKST 941 + W P Y + V+ + + Q P+ P+LP P S + Sbjct: 531 ---------TFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRY 580 Query: 942 PPAPDNGTSAWGEPNES--SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGE 999 P D +G ++ +PG +D N +P+ S+ D G Sbjct: 581 QPQQDMSQEGYGTRSQPPLAPGKPNHED------------LNLIQQERPS--SLPDLSGS 626 Query: 1000 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWM 1059 D TG G +T SQG S+ + + + S+ GG + S + Sbjct: 627 IDDLPTGTEATLSSAVSASG---STSSQGDQSNPAQSPFSPHASPHLS-SIPGGPSPSPV 682 Query: 1060 -NPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGF 1118 +P+ S G +S S GS S+ + M + Sbjct: 683 GSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQ--- 739 Query: 1119 RPPNSKDMGTTDSGPYFEKLTLP------------FSNQDGCLGDEAPCSPFSPSPSYKL 1166 R P G +GP P SN G G + S + P +Y Sbjct: 740 RNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSR 797 Query: 1167 SPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP--VQPLNSSPSL 1224 P+ S +P+ S G G+ G+ N+ +G P PL PS Sbjct: 798 PPAYSGVPSASYSGPGPGM-------------GISANNQMHGQGPSQPCGAVPLGRMPSA 844 Query: 1225 RAQ---VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLA 1281 Q P S S+ + Q G+ P + V + A++ Q + Sbjct: 845 GMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR-- 902 Query: 1282 CQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPV 1341 Q Q L+ + SQ + S + Q P M +S + V Sbjct: 903 -QGSFPGMNQSGLMASSSPYSQPMNNSS--------SLMNTQAPPYSMAPAMVNSSAASV 953 Query: 1342 GPKPHLDNMVPNALNVGLP---DLQTKG-PIPGYGSGFSSGGMDYGMVGGK--EAGTESR 1395 G D M P + LP D + +G P P S SS G K E G E Sbjct: 954 G---LADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPE 1010 Query: 1396 FKQW 1399 K W Sbjct: 1011 RKLW 1014 Score = 35.0 bits (79), Expect = 0.67 Identities = 82/347 (23%), Positives = 123/347 (35%), Gaps = 66/347 (19%) Query: 81 PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVT 140 P A+Y+P + R++ QQD G G P APG PN+ + Sbjct: 566 PPQAQYLPSQSQQRYQPQQD--------------MSQEGYGTRSQPPLAPG-KPNHEDLN 610 Query: 141 GALLQSE--------SGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192 L+Q E SG+ D G A + A S GS +S + ++P Sbjct: 611 --LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 668 Query: 193 DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS--- 249 S + P + + S N S S P S S +PGS + GSQ +S+S Sbjct: 669 HLSSIPGGPSPSPVGSPVGS-----NQSRSGPISPAS-IPGSQMPPQPPGSQSESSSHPA 722 Query: 250 -------------SGNECNLGVWKSDPKAKSVQSSNSTT---ENNNGLGNWRNVSGQDRI 293 +G + N + + P+ S + + + G+ +++ + Sbjct: 723 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY 782 Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENA 353 GP S + P N S PA G S + Q + Sbjct: 783 GP--QMSQYGPQGNYSRPPAY-------SGVPSASYSGPGPGMGISANNQMHGQGPSQPC 833 Query: 354 GVNFVVSGR-EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMG 399 G V GR A + N P GN +S+ SSP M +G P GMG Sbjct: 834 GA--VPLGRMPSAGMQNRPFP--GNMSSMTPSSPG-MSQQGGP-GMG 874 Score = 34.7 bits (78), Expect = 0.88 Identities = 46/188 (24%), Positives = 70/188 (37%), Gaps = 38/188 (20%) Query: 1313 LARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372 L + ++ QQQQQQQQ+Q + HP+ L A G PD++ P G Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPG-PDMEQ--PQHGGA 104 Query: 1373 SGFSSGGM----------------DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANM 1416 ++GG D G+ AG R++ GL ++ TQ+ Sbjct: 105 KDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG--GRYEH-----PGLGALGTQQP-- 155 Query: 1417 HKNGAIVAPGKTRGGSPYNQFDIIPGDTL------GGHTGPAGDSWLPAKSPPTNKIGSK 1470 + PG G + +F+ G GG GP D +SP + S Sbjct: 156 ----PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211 Query: 1471 SSNASWPP 1478 S+ A+ P Sbjct: 212 SAAAAGAP 219 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 60.5 bits (145), Expect = 1e-08 Identities = 65/235 (27%), Positives = 74/235 (31%), Gaps = 27/235 (11%) Query: 767 KPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826 KP +GG G G +G RSP G P N+ PP Sbjct: 56 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115 Query: 827 QQPPPPQPEASGSWGGPPPP--PPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSIS 884 +P P P+ GPPPP P G + S S P P+ P G + PQ Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ--PQGPP 173 Query: 885 RKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWS---KST 941 G G K QG P P +P P P KS S S K Sbjct: 174 PPPGKPQGPPPQG-------------GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ 220 Query: 942 PPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDG 996 P P G G P PG G G GN P P KP Q G Sbjct: 221 GPPPQGGNQPQGPP--PPPG----KPQGPPPQG-GNKPQGPPPPGKPQGPPAQGG 268 Score = 58.2 bits (139), Expect = 7e-08 Identities = 57/207 (27%), Positives = 67/207 (32%), Gaps = 25/207 (12%) Query: 805 AWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPP--PPGNVRPSNSSWSSGP 862 A N G P NK PP +P P P+ GPPPP P G + S S Sbjct: 33 AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92 Query: 863 QPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPRE 922 P P+ P G +P + G P N QG P P + Sbjct: 93 PPGKPQGPPPQGGNQP------QGPPPPPGKPQGPPPQGGN---------RPQGPPPPGK 137 Query: 923 PNLPTPMTSKSASVWS---KSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTP 979 P P P KS S S K P P G G P PG + G P Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--PPPGKPQGPPPQGGKKPQGPPP 195 Query: 980 ANAPNAMKP---NSKSMQDGWGESDGP 1003 P P S+S Q G+ GP Sbjct: 196 PGKPQGPPPQGDKSRSSQSPPGKPQGP 222 Score = 43.5 bits (101), Expect = 0.002 Identities = 45/170 (26%), Positives = 66/170 (38%), Gaps = 13/170 (7%) Query: 710 GGGRPDEKTPSSWNENPSKDQGWG--GGRQPNQGWSSGK-NGWGEEVDQTKNSNWESSAS 766 GG +P P P K QG GG++P GK G + D++++S +S Sbjct: 165 GGNQPQGPPPP-----PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS--QSPPG 217 Query: 767 KPVSGWGEGGQNEIGTWGNGGNAS-LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQP 825 KP +GG G G +GG + P G +K + P Sbjct: 218 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277 Query: 826 PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQ--PATPKDEEPS 873 P +P P + + GPPPP GN + + + PQ P P+ PS Sbjct: 278 PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 327 Score = 36.6 bits (83), Expect = 0.23 Identities = 33/142 (23%), Positives = 44/142 (30%), Gaps = 23/142 (16%) Query: 767 KPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826 KP +GG+ G G +G +SP G P N+ PP Sbjct: 178 KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237 Query: 827 QQPPPPQPEASGSWGGPPPP-------------------PPGNVRPSNSSWSSGPQ---- 863 +P P P+ GPPPP PPG + + PQ Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297 Query: 864 PATPKDEEPSGWEEPSPQSISR 885 PA ++P PQ R Sbjct: 298 PAGGNPQQPQAPPAGQPQGPPR 319 Score = 33.1 bits (74), Expect = 2.6 Identities = 22/82 (26%), Positives = 29/82 (35%), Gaps = 3/82 (3%) Query: 48 SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQQDHKVL 104 ++P P G PP GG+ ++ P G+ PP P+ PP Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 308 Query: 105 LKRGQPPPPSCMLLGGGAGPPP 126 GQP P GG PP Sbjct: 309 PPAGQPQGPPRPPQGGRPSRPP 330 Score = 32.7 bits (73), Expect = 3.3 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 12/97 (12%) Query: 54 SPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQ----QDHKVLLK 106 SP G PP GGN + P G+ PP P+ PP + Q Q K Sbjct: 92 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151 Query: 107 RGQP-----PPPSCMLLGGGAGPPPCTAPGANPNNAQ 138 R P PPP G PPP G P + Sbjct: 152 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188 Score = 32.7 bits (73), Expect = 3.3 Identities = 28/103 (27%), Positives = 36/103 (34%), Gaps = 13/103 (12%) Query: 51 TAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQ--------Q 99 ++ SP G PP GGN + P G+ PP P+ PP + Q + Sbjct: 211 SSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270 Query: 100 DHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGA 142 G+P P GPPP G NP Q A Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPP--PAGGNPQQPQAPPA 311 >gi|110347429 mediator complex subunit 12 [Homo sapiens] Length = 2177 Score = 59.7 bits (143), Expect = 3e-08 Identities = 68/248 (27%), Positives = 94/248 (37%), Gaps = 24/248 (9%) Query: 1133 PYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVS-------LGAIGTGL 1185 P ++L G LG ++ +PS SY L S P VS G GT + Sbjct: 1906 PQGQRLRQQLQQSQGMLG-QSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMV 1964 Query: 1186 NPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPS--LRAQVPPQ----FISPQVSA 1239 P + +H + + L P + L PS + Q P + + S Sbjct: 1965 PPSYSSQPYQSTH------PSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSH 2018 Query: 1240 SMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQN-- 1297 L+Q P + G Q + A+L + Q Q Q Q QQQQQQQ Q Sbjct: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYH 2078 Query: 1298 --QRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNAL 1355 Q++ Q +RQQQ+QQ + QQQQQQQQ+Q + P P Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138 Query: 1356 NVGLPDLQ 1363 GL Q Sbjct: 2139 RQGLQQTQ 2146 Score = 33.1 bits (74), Expect = 2.6 Identities = 31/78 (39%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQ----QQLLQNQRKIS-QAVRQ-QQEQQL 1313 Q QQ Q Q Q Q Q QQQQQ Q Q+Q + Q ++Q QQ+QQ Sbjct: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQT 2151 Query: 1314 ARMVSALQQQQQQQQRQP 1331 A +V LQQQ Q QP Sbjct: 2152 AALVRQLQQQLSNTQPQP 2169 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 59.7 bits (143), Expect = 3e-08 Identities = 84/305 (27%), Positives = 100/305 (32%), Gaps = 33/305 (10%) Query: 710 GGGRPDEKTPSSWNENPSKDQGWG--GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767 GG +P P P K QG GG +P GK G K+ + S K Sbjct: 64 GGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQ-GPPPQGDKSRSPRSPPGK 117 Query: 768 PVSGWGEGGQNEIGTWGNGGNAS-LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826 P +GG G G +GG + P G P NK + PP Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP 177 Query: 827 QQPPPPQPEASGSWGGPPPPP--PGNVRPSNSSWSSG-PQPATPKDEEPSGWEEP----S 879 +P P P+ GPPPPP P P + G P P P+ P G + S Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237 Query: 880 PQSISRKMDIDDGTSAWGDPNSYNYKN--VNLWDKNSQGGPAPREPNLPTPM-TSKSASV 936 P + G G P QG P P +P P P SKS S Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS- 296 Query: 937 WSKSTP-----PAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSK 991 S+S P P P G G P PG G G GN P P KP Sbjct: 297 -SRSPPGKPQGPPPQGGNQPQGPP--PPPG----KPQGPPPQG-GNKPQGPPPPGKPQGP 348 Query: 992 SMQDG 996 Q G Sbjct: 349 PPQGG 353 Score = 57.4 bits (137), Expect = 1e-07 Identities = 58/215 (26%), Positives = 70/215 (32%), Gaps = 18/215 (8%) Query: 805 AWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP--PGNVRPSNSSWSSG- 861 A N G P NK PP +P P P+ GPPPPP P P + G Sbjct: 33 AGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92 Query: 862 PQPATPKDEEPSGWEEPSPQSISRKMD---IDDGTSAWGDPNSYNYKN--VNLWDKNSQG 916 P P P+ P G + SP+S K G G P QG Sbjct: 93 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152 Query: 917 GPAPREPNLPTPM----TSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGAST 972 P P +P P P + S S K P P G G P PG + Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP--PPPGKPQGPPPQGGN 210 Query: 973 TGWGNTPANAPNAMKP----NSKSMQDGWGESDGP 1003 G P P P S+S + G+ GP Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245 Score = 45.4 bits (106), Expect = 5e-04 Identities = 44/169 (26%), Positives = 61/169 (36%), Gaps = 10/169 (5%) Query: 710 GGGRPDEKTPSSWNENPSKDQGWG--GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767 GG +P P P K QG GG +P GK +K+ + S K Sbjct: 249 GGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK 303 Query: 768 PVSGWGEGGQNEIGTWGNGGNAS-LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826 P +GG G G +GG + P G P +K + PP Sbjct: 304 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPP 363 Query: 827 QQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQ--PATPKDEEPS 873 +P P + + GPPPP GN + + + PQ P P+ PS Sbjct: 364 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 412 Score = 33.9 bits (76), Expect = 1.5 Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 21/76 (27%) Query: 51 TAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQP 110 +A SP G PP GGN P G PP + P+ PP Q +K +G P Sbjct: 234 SARSPPGKPQGPPPQGGNQ------PQGPPPPPGK--PQGPPP----QGGNK---PQGPP 278 Query: 111 PPPSCMLLGGGAGPPP 126 PP G GPPP Sbjct: 279 PP------GKPQGPPP 288 Score = 33.1 bits (74), Expect = 2.6 Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 13/94 (13%) Query: 54 SPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFR-----CQQDHKVLL 105 SP G PP GGN + P G+ PP P+ PP + Q D+K Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS 172 Query: 106 KRGQP-----PPPSCMLLGGGAGPPPCTAPGANP 134 R P PPP G PPP G P Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206 Score = 33.1 bits (74), Expect = 2.6 Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 13/97 (13%) Query: 51 TAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFR-----CQQDHK 102 ++ SP G PP GGN + P G+ PP P+ PP + Q D+K Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231 Query: 103 VLLKRGQP-----PPPSCMLLGGGAGPPPCTAPGANP 134 R P PPP G PPP G P Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 268 Score = 32.7 bits (73), Expect = 3.3 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 20/79 (25%) Query: 48 SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKR 107 ++P P G PP GG+ ++ P G+P PP+ Q + Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP--------PPQGGNQ-------PQ 316 Query: 108 GQPPPPSCMLLGGGAGPPP 126 G PPPP G GPPP Sbjct: 317 GPPPPP-----GKPQGPPP 330 Score = 32.7 bits (73), Expect = 3.3 Identities = 22/82 (26%), Positives = 29/82 (35%), Gaps = 3/82 (3%) Query: 48 SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQQDHKVL 104 ++P P G PP GG+ ++ P G+ PP P+ PP Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 393 Query: 105 LKRGQPPPPSCMLLGGGAGPPP 126 GQP P GG PP Sbjct: 394 PPAGQPQGPPRPPQGGRPSRPP 415 Score = 32.3 bits (72), Expect = 4.4 Identities = 26/73 (35%), Positives = 30/73 (41%), Gaps = 21/73 (28%) Query: 54 SPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPP 113 SP G PP GGN P G PP + P+ PP Q +K +G PPP Sbjct: 52 SPPGKPQGPPPQGGNQ------PQGPPPPPGK--PQGPPP----QGGNK---PQGPPPP- 95 Query: 114 SCMLLGGGAGPPP 126 G GPPP Sbjct: 96 -----GKPQGPPP 103 Score = 32.3 bits (72), Expect = 4.4 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 20/79 (25%) Query: 48 SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKR 107 ++P P G PP G N ++ P G+P PP+ Q + Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP--------PPQGGNQ-------PQ 254 Query: 108 GQPPPPSCMLLGGGAGPPP 126 G PPPP G GPPP Sbjct: 255 GPPPPP-----GKPQGPPP 268 Score = 32.0 bits (71), Expect = 5.7 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 20/79 (25%) Query: 48 SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKR 107 ++P P G PP G N ++ P G+P PP+ Q + Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP--------PPQGGNQ-------PQ 192 Query: 108 GQPPPPSCMLLGGGAGPPP 126 G PPPP G GPPP Sbjct: 193 GPPPPP-----GKPQGPPP 206 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 58.9 bits (141), Expect = 4e-08 Identities = 47/120 (39%), Positives = 61/120 (50%), Gaps = 22/120 (18%) Query: 1259 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQR---------KISQAVRQQQ 1309 P+LS Q + L QL Q Q QL Q LQQQQQQQL Q Q+ + Q ++QQQ Sbjct: 3887 PKLSAQPMGSLQQLQQ--QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQ 3944 Query: 1310 EQQLARMVSALQQQQQQQQ---------RQPGMKHSPSHPVGPKPHLDNMVPNALNVGLP 1360 +QQL + LQQQQQQQQ +Q G+ + + P+ V AL G+P Sbjct: 3945 QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV--ALGPGMP 4002 Score = 54.7 bits (130), Expect = 8e-07 Identities = 46/131 (35%), Positives = 61/131 (46%), Gaps = 15/131 (11%) Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLA----- 1314 QL QQ+ Q Q+ Q Q Q LQQQQQQ Q Q++ Q +QQQ+QQ+ Sbjct: 3925 QLQQQQLQQQQQQQQLQQQQ---QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981 Query: 1315 -RMVSALQQQQQQQQRQPGMKHSP----SHP--VGPKPHLDNMVPNALNVGLPDLQTKGP 1367 ++S QQQQQQ PGM P S P +GP L N ++ + T+GP Sbjct: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041 Query: 1368 IPGYGSGFSSG 1378 G + G Sbjct: 4042 STHQGGPLAIG 4052 Score = 48.5 bits (114), Expect = 6e-05 Identities = 65/214 (30%), Positives = 87/214 (40%), Gaps = 38/214 (17%) Query: 1159 SPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPL 1218 S SP G LP G GL P QG G G G+ P QP Sbjct: 3622 SQSPRLLTKLPGQLLP-------GHGLQPP-----QGPPGGQAGGLRLTPGGMALPGQP- 3668 Query: 1219 NSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF 1278 P L + Q + P+ G PG L+ + + S+L Q Q Sbjct: 3669 -GGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG------NLALRSLGPDSRLLQERQL 3721 Query: 1279 QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPS 1338 QL QQQ+ QL Q K+ Q +QQQ+QQ A+QQQQQQ PG++ + Sbjct: 3722 QL-------QQQRMQLAQ---KLQQQQQQQQQQQHLLGQVAIQQQQQQ---GPGVQ--TN 3766 Query: 1339 HPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372 +GPKP ++P + + GL +Q P P G Sbjct: 3767 QALGPKP--QGLMPPSSHQGLL-VQQLSPQPPQG 3797 Score = 42.7 bits (99), Expect = 0.003 Identities = 63/228 (27%), Positives = 85/228 (37%), Gaps = 45/228 (19%) Query: 1157 PFSPSPSYKLSPSGSTLPNVSLGA-IGTGLNPQNFAARQGGSHGLFGNSTA--------- 1206 P + +L+P G LP G + T L Q GG+ L G S Sbjct: 3648 PGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALR 3707 Query: 1207 ---------QSRGLHTPVQPLNSSPSLRAQVPPQ----FISPQVSASMLKQF-----PNS 1248 Q R L Q + + L+ Q Q + QV+ +Q N Sbjct: 3708 SLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQ 3767 Query: 1249 GLSPGLFNVGPQLSPQQIAMLS---QLPQIPQFQLA-CQLLLQQQQ-----------QQQ 1293 L P + P S Q + + Q PQ PQ L Q+ + QQQ +Q Sbjct: 3768 ALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQV 3827 Query: 1294 LLQNQRKISQAVRQQQEQQLA--RMVSALQQQQQQQQRQPGMKHSPSH 1339 L+ R +S QQ Q L R+V+A QQQQQQQ +Q G SH Sbjct: 3828 LMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH 3875 Score = 41.6 bits (96), Expect = 0.007 Identities = 50/180 (27%), Positives = 72/180 (40%), Gaps = 36/180 (20%) Query: 1259 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVS 1318 P+ +++ ++++ Q QL Q+ QQ++ L+ R +QQQ+QQ Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQLD-QVRKQQKEHTNLMAEYRN-----KQQQQQQ------ 3604 Query: 1319 ALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSG--FS 1376 QQQQQQQQ + SPS P L +P L G +GP G G + Sbjct: 3605 --QQQQQQQQHSAVLALSPSQ----SPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658 Query: 1377 SGGMDY-GMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYN 1435 GGM G GG T ++A Q+ H GA G + G P N Sbjct: 3659 PGGMALPGQPGGPFLNT---------------ALAQQQQQQHSGGAGSLAGPSGGFFPGN 3703 Score = 40.0 bits (92), Expect = 0.021 Identities = 95/379 (25%), Positives = 140/379 (36%), Gaps = 41/379 (10%) Query: 1195 GGSHGLFGN--STAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSP 1252 GGSHG G+ S+ S H QP S + + PQ ML++ + P Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ--QPMLERPMQNNTGP 4170 Query: 1253 GLFNVGPQL-SPQQIAMLSQLPQIPQFQLACQLLL-----------QQQQQQQLLQNQRK 1300 GP L S Q + + +P + Q + Q +L QQQQQ Q L QR+ Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230 Query: 1301 I--SQAVRQQQE-QQLARMVSALQQQ---QQQQQRQPGMKHSPSHPVGPKPHLDN----- 1349 + SQAVRQ Q+ S LQ Q Q PG + P +G P Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290 Query: 1350 MVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRF---KQWTSMMEGL 1406 P AL+ G P L P P S + TE++ T +G Sbjct: 4291 APPGALSTG-PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG- 4348 Query: 1407 PSVATQEANMHKNGAIVAPGK-TRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTN 1465 P++ + A +A ++G P++ P D L P S +P N Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWD-----PPDNLAETQKPEQSSLVPGHLDQVN 4403 Query: 1466 -KIGSKSSNASWPPEFQPGVPWKGIQNIDPES--DPYVTPGSVLGGTATSPIVDTDHQLL 1522 ++ ++S S E + G Q++ E+ +P PG+ P + H LL Sbjct: 4404 GQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLL 4463 Query: 1523 RDNTTGSNSSLNTSLPSPG 1541 + N L+T S G Sbjct: 4464 QKLLRAKNVQLSTGRGSEG 4482 Score = 33.9 bits (76), Expect = 1.5 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 19/128 (14%) Query: 1215 VQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQ 1274 VQ L+ P Q P + P A + +Q P + +GPQ P + +++Q Sbjct: 3787 VQQLSPQPP---QGPQGMLGPAQVAVLQQQHPGA--------LGPQ-GPHRQVLMTQSRV 3834 Query: 1275 IPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMK 1334 + QLA QQ Q L+ ++ +Q +QQQ+ Q ++ L QQ G Sbjct: 3835 LSSPQLA-------QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQP 3887 Query: 1335 HSPSHPVG 1342 + P+G Sbjct: 3888 KLSAQPMG 3895 Score = 32.7 bits (73), Expect = 3.3 Identities = 41/179 (22%), Positives = 58/179 (32%), Gaps = 18/179 (10%) Query: 797 WEDCKRSPAWNE--TGRQPNSWNKQHQQQQPPQQPPP------PQPEASGSWG------- 841 +E+ SP E T P + ++ P PPP P PEAS + Sbjct: 549 FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608 Query: 842 GPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNS 901 PPP P +S S P +P P P +SR + + P Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668 Query: 902 YNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP 960 ++ + S P P L P S + +P +P S P E SP Sbjct: 669 ---SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724 Score = 32.7 bits (73), Expect = 3.3 Identities = 31/119 (26%), Positives = 44/119 (36%), Gaps = 12/119 (10%) Query: 826 PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISR 885 PQ+PPP Q A PP P RP + + P TP+ + P E R Sbjct: 2349 PQEPPPAQALAPS-----PPSHPDIFRPGSYTDPYAQPPLTPRPQPPP--PESCCALPPR 2401 Query: 886 KMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPA 944 + D + P S + L + P E P+P+T + S S PP+ Sbjct: 2402 SLPSDPFSRVPASPQSQSSSQSPLTPR-----PLSAEAFCPSPVTPRFQSPDPYSRPPS 2455 Score = 32.7 bits (73), Expect = 3.3 Identities = 56/221 (25%), Positives = 84/221 (38%), Gaps = 43/221 (19%) Query: 1160 PSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQP-- 1217 PSP + P + ++G GL P + G G S G HT + Sbjct: 3129 PSPCQFTIATPKVEPAPAANSLGLGLKPGQ--SMMGSRDTRMGTGPFSSSG-HTAEKASF 3185 Query: 1218 -LNSSPSLRAQVPPQFISPQVSASMLKQFPNSG---LSPGLFNVGPQLSPQQIAML-SQL 1272 P P P S+ + K SG L G G +L + +++ S+L Sbjct: 3186 GATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASEL 3245 Query: 1273 PQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ-- 1330 P LL++ LL++++K Q++QQL+ + QQQQQQQQ+ Sbjct: 3246 P----------LLIED-----LLEHEKK-----ELQKKQQLSAQLQPAQQQQQQQQQHSL 3285 Query: 1331 ---PG------MKHSPSHP--VGPKPHLDNMVPNALNVGLP 1360 PG + H S P G + L + A GLP Sbjct: 3286 LSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLP 3326 Score = 31.6 bits (70), Expect = 7.4 Identities = 75/289 (25%), Positives = 108/289 (37%), Gaps = 36/289 (12%) Query: 1101 AMNLGDFNDIMRKDRSGFRPPN---SKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSP 1157 A+ G ++ K SG +PPN S G P + T P + + L P P Sbjct: 2497 ALPAGPAGELHAKVPSG-QPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP-QP 2554 Query: 1158 FSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQ--NFAARQGGSH------GLFGNSTAQSR 1209 P P S G P +LG PQ N+ G H G ST +S Sbjct: 2555 GLPPPHGINSHFG---PGPTLG------KPQSTNYTVATGNFHPSGSPLGPSSGSTGESY 2605 Query: 1210 GLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGL-SPGLFNVGPQLSPQQIAM 1268 GL +P++P PS+ P P +S ++ SG+ SP P Sbjct: 2606 GL-SPLRP----PSVLPPPAPDGSLPYLSHGASQR---SGITSPVEKREDPGTGMGSSLA 2657 Query: 1269 LSQLP--QIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQ--QQEQQLARMVSALQQQQ 1324 ++LP Q P Q L++Q+Q+Q L+ Q R +QE++ A + Sbjct: 2658 TAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPP 2717 Query: 1325 QQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 1373 +P G P ++L VGLP + GPI G GS Sbjct: 2718 GSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL-VGLPPSKLSGPILGPGS 2765 Score = 31.6 bits (70), Expect = 7.4 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 18/78 (23%) Query: 823 QQPPQQPPPPQPEASGSWGGP--PPPPPGNVR-PSNSSWSSGP-------------QPAT 866 Q PP+ P PP ++G GP P PPP + + P S P P T Sbjct: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343 Query: 867 PKDEEPSGWEEPSPQSIS 884 PK + P+ EP P +S Sbjct: 4344 PKPQGPT--LEPPPGRVS 4359 >gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 isoform d [Homo sapiens] Length = 756 Score = 58.5 bits (140), Expect = 6e-08 Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 52/247 (21%) Query: 705 NSSNWGGGRPDEKTPSSWNENPSKDQGWGGG--RQPNQGWSSGKNGWGEEVDQTKNSNWE 762 N G P EK + + +G GGG R N+G G G + Sbjct: 495 NEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNR--------- 545 Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQ 822 G GG N G + G S+ W + R N S+N+ QQ Sbjct: 546 -------GGGSGGGGNYRGGFNRSGGGGY-SQNRWGNNNRD---NNNSNNRGSYNRAPQQ 594 Query: 823 QQPPQQPPPPQPEASGSWGGPPPPP---PGNVRPSNSSW--SSGPQPATPKDEEPSGWEE 877 Q PPQQPPPPQP PPPPP P P S++ +S ++ P+ Sbjct: 595 QPPPQQPPPPQPPPQ----QPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSY 650 Query: 878 PSPQSISRKMDIDDGTSAWG---------DPNSYNYKNVNLWDKNSQGG--PAPREPNLP 926 PQ + + G + G P +YNY S GG PAP P P Sbjct: 651 SPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNY--------GSYGGYNPAPYTP--P 700 Query: 927 TPMTSKS 933 P T+++ Sbjct: 701 PPPTAQT 707 Score = 38.9 bits (89), Expect = 0.047 Identities = 36/171 (21%), Positives = 62/171 (36%), Gaps = 16/171 (9%) Query: 695 TGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754 +GG +Y+ + + GGG + ++ +N + + R P Q + + Sbjct: 549 SGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPP 608 Query: 755 Q--TKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQ 812 Q ++ + + P + N G+ N +++S + P +N+ G Sbjct: 609 QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYS 668 Query: 813 PNSWNKQHQQQQPPQQPPPPQPEASGSWGG-------PPPPPPGNVRPSNS 856 PP PPPP GS+GG PPPPP P S Sbjct: 669 QG-------YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPS 712 Score = 34.7 bits (78), Expect = 0.88 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 5/64 (7%) Query: 429 RGPSGTDTVSGQSNSGNNGNNGKER---EDSWKGASVQKSTGSKNDSWDNNNRSTGGSWN 485 RGP G + Q+ G +G G R S G Q G+ N DNNN + GS+N Sbjct: 532 RGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNR--DNNNSNNRGSYN 589 Query: 486 FGPQ 489 PQ Sbjct: 590 RAPQ 593 >gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 isoform a [Homo sapiens] Length = 856 Score = 58.5 bits (140), Expect = 6e-08 Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 52/247 (21%) Query: 705 NSSNWGGGRPDEKTPSSWNENPSKDQGWGGG--RQPNQGWSSGKNGWGEEVDQTKNSNWE 762 N G P EK + + +G GGG R N+G G G + Sbjct: 595 NEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNR--------- 645 Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQ 822 G GG N G + G S+ W + R N S+N+ QQ Sbjct: 646 -------GGGSGGGGNYRGGFNRSGGGGY-SQNRWGNNNRD---NNNSNNRGSYNRAPQQ 694 Query: 823 QQPPQQPPPPQPEASGSWGGPPPPP---PGNVRPSNSSW--SSGPQPATPKDEEPSGWEE 877 Q PPQQPPPPQP PPPPP P P S++ +S ++ P+ Sbjct: 695 QPPPQQPPPPQPPPQ----QPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSY 750 Query: 878 PSPQSISRKMDIDDGTSAWG---------DPNSYNYKNVNLWDKNSQGG--PAPREPNLP 926 PQ + + G + G P +YNY S GG PAP P P Sbjct: 751 SPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNY--------GSYGGYNPAPYTP--P 800 Query: 927 TPMTSKS 933 P T+++ Sbjct: 801 PPPTAQT 807 Score = 38.9 bits (89), Expect = 0.047 Identities = 36/171 (21%), Positives = 62/171 (36%), Gaps = 16/171 (9%) Query: 695 TGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754 +GG +Y+ + + GGG + ++ +N + + R P Q + + Sbjct: 649 SGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPP 708 Query: 755 Q--TKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQ 812 Q ++ + + P + N G+ N +++S + P +N+ G Sbjct: 709 QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYS 768 Query: 813 PNSWNKQHQQQQPPQQPPPPQPEASGSWGG-------PPPPPPGNVRPSNS 856 PP PPPP GS+GG PPPPP P S Sbjct: 769 QG-------YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPS 812 Score = 34.7 bits (78), Expect = 0.88 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 5/64 (7%) Query: 429 RGPSGTDTVSGQSNSGNNGNNGKER---EDSWKGASVQKSTGSKNDSWDNNNRSTGGSWN 485 RGP G + Q+ G +G G R S G Q G+ N DNNN + GS+N Sbjct: 632 RGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNR--DNNNSNNRGSYN 689 Query: 486 FGPQ 489 PQ Sbjct: 690 RAPQ 693 >gi|4504733 insulin receptor substrate 4 [Homo sapiens] Length = 1257 Score = 57.8 bits (138), Expect = 1e-07 Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 16/196 (8%) Query: 654 ESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGR 713 E + + + N G G+ + +Q SG + P N G + + + G+ Sbjct: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYM--------PMNNWGSGNGRGSGGGQGSNGQ 510 Query: 714 PDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWG 773 S N+ + QG GG+ N G SG N + T + +P G G Sbjct: 511 GSSSHSSGGNQCSGEGQGSRGGQGSN-GQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG 569 Query: 774 EGGQNEIGTW-GNGGNASLASKGGWEDCKRSPAWNETGRQPNSWN------KQHQQQQPP 826 GG G G+GG + G K S E G+ + + QQQ PP Sbjct: 570 SGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPP 629 Query: 827 QQPPPPQPEASGSWGG 842 PPPP P +G GG Sbjct: 630 PPPPPPPPPPAGGTGG 645 Score = 41.2 bits (95), Expect = 0.009 Identities = 40/130 (30%), Positives = 47/130 (36%), Gaps = 26/130 (20%) Query: 479 STGGSWNFG----PQDSND-----------NKWGEGNKMTSGVSQGEWKQPTGSDELKIG 523 S GS NFG PQ D N WG GN SG QG Q + S Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520 Query: 524 EWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGS- 582 + SG Q S G N +G G Q G+ ++ GGQ G H +G Sbjct: 521 QCSGEGQ-GSRGGQGSNGQG------SGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGG 573 Query: 583 ---SDSHNSG 589 D H SG Sbjct: 574 QGPGDGHGSG 583 Score = 39.7 bits (91), Expect = 0.027 Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 19/169 (11%) Query: 428 ARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG-GSWNF 486 A P+ +S + + +GN G+E K + GS D NN +G G + Sbjct: 447 AEAPNNGARLSSEVSGSGSGNFGEEGNPQGK----EDQEGSGGDYMPMNNWGSGNGRGSG 502 Query: 487 GPQDSN---DNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKG 543 G Q SN + G SG QG + GS+ G+ SG NQ S G Sbjct: 503 GGQGSNGQGSSSHSSGGNQCSGEGQGS-RGGQGSN----GQGSGGNQ--CSRDGQGTAGG 555 Query: 544 HPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRS 592 H G Q P G S G +G +G SG+ S Sbjct: 556 H----GSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS 600 Score = 38.9 bits (89), Expect = 0.047 Identities = 103/474 (21%), Positives = 159/474 (33%), Gaps = 66/474 (13%) Query: 388 PMENKGMPFGMGL--GNTSRSTDAPSQSTGDRK-----TGSVGSWGAARGPSGTDTVS-- 438 PM N G G G G S + S S+G + GS G G+ SG + S Sbjct: 489 PMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRD 548 Query: 439 GQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGE 498 GQ +G +G+ G +R G+ + G + S +++GG G +D Sbjct: 549 GQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGS--GGGKNSGGGKGSGSGKGSDGDGER 606 Query: 499 GNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH---PLPENQGNAQA 555 G + G+ Q P P TG G ++G A Sbjct: 607 GKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRG-ATK 665 Query: 556 PCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDP 615 C + +E+ + H+A + D Y P P V L+S +D P Sbjct: 666 EC-KEAKEVKDAEIPEGAARGPHRARAFDEDEDD--PYVPMRP---GVATPLVSSSDYMP 719 Query: 616 RVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQ 675 N + + + D + A T D S+S+ Sbjct: 720 MAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDY 779 Query: 676 MKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNEN-------PSK 728 M G A K+P+N G + K + SS + P +P N+N P K Sbjct: 780 MFMAPG---AGAIPKNPRNPQGGSSSK-SWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGK 835 Query: 729 DQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788 G G ++ + W + D + E S SKP G+GG+ Sbjct: 836 FLGRGLDKEVSYNW--------DPKDAASKPSGEGSFSKP---------------GDGGS 872 Query: 789 ASLASKGGWEDCKRSPAWNETGRQPNSWN---KQHQQQQPPQQPPPPQPEASGS 839 S S P N+ ++PN + K ++ + PQ+P Q EA S Sbjct: 873 PSKPS-------DHEPPKNK-AKRPNRLSFITKGYKIKPKPQKPTHEQREADSS 918 Score = 37.4 bits (85), Expect = 0.14 Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 6/131 (4%) Query: 952 WGEPNE--SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES----DGPVT 1005 WG N S G G +S + GN + + S G G + DG T Sbjct: 493 WGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGT 552 Query: 1006 GARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQ 1065 H S + GG + G QG H S G + S KG + D K+ Sbjct: 553 AGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKK 612 Query: 1066 FSNMGLLSQTE 1076 S G L+Q++ Sbjct: 613 RSYFGKLTQSK 623 Score = 34.3 bits (77), Expect = 1.1 Identities = 48/236 (20%), Positives = 77/236 (32%), Gaps = 20/236 (8%) Query: 643 EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYK 702 +G + +G+ S Q G SN SG + S + + G Sbjct: 505 QGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRP 564 Query: 703 NNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGR----QPNQGWSSGKNGWGEEVDQTKN 758 + GG P + S +N +G G G+ +G S K + ++ Q+K Sbjct: 565 GGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQ 624 Query: 759 SNWESSASKPVSGWGEGGQNEIGTWGNGGNASL---ASKGGWEDCKRSPAWNE------T 809 P GG G +GG L +G ++CK + + Sbjct: 625 QQMPPPPPPPPPPPPAGGTG--GKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGA 682 Query: 810 GRQPN---SWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGP 862 R P+ ++++ P +P P S S P P NV S S P Sbjct: 683 ARGPHRARAFDEDEDDPYVPMRPGVATPLVSSS--DYMPMAPQNVSASKKRHSRSP 736 >gi|33286444 mastermind-like 2 [Homo sapiens] Length = 1156 Score = 57.8 bits (138), Expect = 1e-07 Identities = 66/236 (27%), Positives = 99/236 (41%), Gaps = 35/236 (14%) Query: 1160 PSPSY---KLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPV- 1215 PSPS+ SP S +P V+ G G N+ + G S ++G H V Sbjct: 481 PSPSFGQQTFSPQSSPMPGVA-GGSGQSKVMANYMYKAGPS----------AQGGHLDVL 529 Query: 1216 ---QPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQL 1272 +P + S S P Q + L F + + + +V P + + +Q Sbjct: 530 MQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQ 589 Query: 1273 PQIPQFQLACQLLLQQQQQQQLLQNQRKISQ--AVRQQQEQQLARMVSALQQQQQQQQRQ 1330 Q Q Q Q QQQQQQQ Q Q++ Q ++ QQ+QQ +SA QQQQQQQQ+Q Sbjct: 590 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQ 649 Query: 1331 PGMKH--------------SPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372 + P+ + +P L + +P + L +Q + PI G G Sbjct: 650 QQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQ-PIAGMG 704 Score = 35.4 bits (80), Expect = 0.51 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 21/127 (16%) Query: 1234 SPQVSASMLKQFPNSGLSPGLFNVGPQLSPQ---------------QIAMLSQLPQIPQF 1278 +P+ S M K S SPGL GP SPQ ++ S +P +PQ Sbjct: 352 TPRPSLPMEKIVIKSEYSPGLTQ-GPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQS 410 Query: 1279 QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPS 1338 Q Q + L + +++S A QQ +Q A + QQ QQQ QP + Sbjct: 411 QAQPQT---GSGASRALPSWQEVSHA--QQLKQIAANRQQHARMQQHQQQHQPTNWSALP 465 Query: 1339 HPVGPKP 1345 GP P Sbjct: 466 SSAGPSP 472 Score = 32.3 bits (72), Expect = 4.4 Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 27/143 (18%) Query: 1214 PVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLF-------------NVGPQ 1260 P Q L S P LR+ +P Q ++ ++ P +G+ + N GP Sbjct: 670 PAQSLPSQPLLRSPLPLQ---QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS 726 Query: 1261 LSPQQIA--------MLSQLPQIPQFQLACQLLLQQQ---QQQQLLQNQRKISQAVRQQQ 1309 SP + M SQ + Q + + LQ+Q Q+QQLL Q+ ++ A + Sbjct: 727 PSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAP 786 Query: 1310 EQQLARMVSALQQQQQQQQRQPG 1332 + Q+ R +S + Q+R G Sbjct: 787 QDQINRHLSRPPPDYKDQRRNVG 809 Score = 31.2 bits (69), Expect = 9.7 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 31/177 (17%) Query: 1193 RQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSL--------RAQVPPQFISPQVSASMLKQ 1244 RQG + LF ++ Q+ V P + PSL + Q Q Q +Q Sbjct: 552 RQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQ 611 Query: 1245 FPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQA 1304 ++ Q QQ + +S Q Q Q Q QQQQQQQ Q Q A Sbjct: 612 QQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPA 671 Query: 1305 --------------------VRQQQEQQLARM---VSALQQQQQQQQRQPGMKHSPS 1338 ++Q Q Q +A M VS Q+Q Q SPS Sbjct: 672 QSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPS 728 Score = 31.2 bits (69), Expect = 9.7 Identities = 25/149 (16%), Positives = 64/149 (42%), Gaps = 16/149 (10%) Query: 3 EKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSP 62 +++Q++++Q + ++++++ +++++ Q+ +Q++ + + +A Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647 Query: 63 PVNGGNNAKRVAVPNGQPPSA--ARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCM---- 116 ++ Q PS+ A+ +P + R K+LL++ Q P + M Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV 707 Query: 117 ----------LLGGGAGPPPCTAPGANPN 135 ++G GP P P +NPN Sbjct: 708 SQQQRQDQHSVVGQNTGPSPSPNPCSNPN 736 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 57.0 bits (136), Expect = 2e-07 Identities = 57/213 (26%), Positives = 71/213 (33%), Gaps = 16/213 (7%) Query: 810 GRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP--PGNVRPSNSSWSSGPQPATP 867 GR+P N+ + PP +P P P+ GPPPPP P P + S GP P Sbjct: 38 GRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG 97 Query: 868 KDEEP-------SGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAP 920 K E P S P P R S P + N GP P Sbjct: 98 KPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPP 157 Query: 921 R--EPNLPTPMT-SKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGN 977 +P P P +KS S ++S P P G + P G+ G G Sbjct: 158 HPGKPEGPPPQEGNKSRS--ARSPPGKPQGPPQQEGNKPQGPPPPGK--PQGPPPAGGNP 213 Query: 978 TPANAPNAMKPNSKSMQDGWGESDGPVTGARHP 1010 AP A KP G P G + P Sbjct: 214 QQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246 Score = 46.6 bits (109), Expect = 2e-04 Identities = 46/176 (26%), Positives = 58/176 (32%), Gaps = 25/176 (14%) Query: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVR- 852 +GG + P + R P Q Q PP P P G+ PPPPPG Sbjct: 84 QGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPER 143 Query: 853 --PSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLW 910 P + S GP P P E P PQ ++ S G P + N Sbjct: 144 PPPQGGNQSQGPPP------HPGKPEGPPPQEGNKSR---SARSPPGKPQGPPQQEGN-- 192 Query: 911 DKNSQGGPAPREPNLP-----TPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPG 961 QG P P +P P P ++ PP P G G P + G Sbjct: 193 --KPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQG----GRPPRPAQG 242 Score = 38.9 bits (89), Expect = 0.047 Identities = 41/172 (23%), Positives = 55/172 (31%), Gaps = 20/172 (11%) Query: 712 GRPDEKTPSSWNEN---------PSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWE 762 G+P+ + P N++ P + GG + GK ++ Sbjct: 76 GKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP 135 Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNAS--LASKGGWEDCKRSPAWNETGRQPNSWNKQH 820 KP +GG G + G +G RSP G NK Sbjct: 136 PPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQ 195 Query: 821 QQQQP--PQQPPP-------PQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQ 863 P PQ PPP PQ +G GPPPPP G P + PQ Sbjct: 196 GPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPPQ 247 Score = 33.5 bits (75), Expect = 2.0 Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 6/85 (7%) Query: 57 GSSPSPPVNGGNNAKRVAVPNGQP---PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPP 113 G PP GN ++ P G+P P P+ PP + Q G P P Sbjct: 160 GKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPA---GGNPQQP 216 Query: 114 SCMLLGGGAGPPPCTAPGANPNNAQ 138 G GPPP G P AQ Sbjct: 217 QAPPAGKPQGPPPPPQGGRPPRPAQ 241 Score = 32.0 bits (71), Expect = 5.7 Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 17/74 (22%) Query: 57 GSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQP--PPPS 114 G PP GGN ++ P G+P E PP Q H+ G+P PPP Sbjct: 97 GKPERPPPQGGNQSQGTPPPPGKP---------ERPPPQGGNQSHRPPPPPGKPERPPPQ 147 Query: 115 CMLLGG--GAGPPP 126 GG GPPP Sbjct: 148 ----GGNQSQGPPP 157 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.305 0.125 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 94,420,952 Number of Sequences: 37866 Number of extensions: 5874815 Number of successful extensions: 47032 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 399 Number of HSP's successfully gapped in prelim test: 1131 Number of HSP's that attempted gapping in prelim test: 25335 Number of HSP's gapped (non-prelim): 14319 length of query: 1833 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1716 effective length of database: 13,817,196 effective search space: 23710308336 effective search space used: 23710308336 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.