Guide to the Human Genome
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Search of human proteins with 241982729

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
         (1833 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ...  3851   0.0  
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ...  3298   0.0  
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s...  1644   0.0  
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]       1100   0.0  
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ...   920   0.0  
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s...   882   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]   102   3e-21
gi|57864582 hornerin [Homo sapiens]                                    93   2e-18
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    82   6e-15
gi|62122917 filaggrin family member 2 [Homo sapiens]                   75   4e-13
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    69   3e-11
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    69   3e-11
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            67   2e-10
gi|161016767 mucin 21 [Homo sapiens]                                   66   3e-10
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   66   4e-10
gi|60097902 filaggrin [Homo sapiens]                                   65   6e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 64   1e-09
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 63   3e-09
gi|11761629 fibrinogen, alpha polypeptide isoform alpha prepropr...    63   3e-09
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop...    63   3e-09
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    62   5e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    60   1e-08
gi|110347429 mediator complex subunit 12 [Homo sapiens]                60   3e-08
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     60   3e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    59   4e-08
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso...    59   6e-08
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso...    59   6e-08
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 58   1e-07
gi|33286444 mastermind-like 2 [Homo sapiens]                           58   1e-07
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    57   2e-07

>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
            sapiens]
          Length = 1833

 Score = 3851 bits (9987), Expect = 0.0
 Identities = 1833/1833 (100%), Positives = 1833/1833 (100%)

Query: 1    MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60
            MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP
Sbjct: 1    MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60

Query: 61   SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120
            SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG
Sbjct: 61   SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120

Query: 121  GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
            GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS
Sbjct: 121  GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180

Query: 181  PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
            PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG
Sbjct: 181  PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240

Query: 241  KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300
            KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS
Sbjct: 241  KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300

Query: 301  NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360
            NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS
Sbjct: 301  NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360

Query: 361  GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420
            GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG
Sbjct: 361  GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420

Query: 421  SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480
            SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST
Sbjct: 421  SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480

Query: 481  GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540
            GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN
Sbjct: 481  GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540

Query: 541  QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600
            QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC
Sbjct: 541  QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600

Query: 601  QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660
            QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT
Sbjct: 601  QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660

Query: 661  KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720
            KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS
Sbjct: 661  KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720

Query: 721  SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
            SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI
Sbjct: 721  SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780

Query: 781  GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
            GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW
Sbjct: 781  GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840

Query: 841  GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900
            GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN
Sbjct: 841  GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900

Query: 901  SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP 960
            SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP
Sbjct: 901  SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP 960

Query: 961  GWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGV 1020
            GWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGV
Sbjct: 961  GWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGV 1020

Query: 1021 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS 1080
            WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS
Sbjct: 1021 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS 1080

Query: 1081 SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTL 1140
            SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTL
Sbjct: 1081 SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTL 1140

Query: 1141 PFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGL 1200
            PFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGL
Sbjct: 1141 PFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGL 1200

Query: 1201 FGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ 1260
            FGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ
Sbjct: 1201 FGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ 1260

Query: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320
            LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL
Sbjct: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320

Query: 1321 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM 1380
            QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM
Sbjct: 1321 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM 1380

Query: 1381 DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII 1440
            DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII
Sbjct: 1381 DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII 1440

Query: 1441 PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 1500
            PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV
Sbjct: 1441 PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 1500

Query: 1501 TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA 1560
            TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA
Sbjct: 1501 TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA 1560

Query: 1561 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR 1620
            KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR
Sbjct: 1561 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR 1620

Query: 1621 SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN 1680
            SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN
Sbjct: 1621 SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN 1680

Query: 1681 LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS 1740
            LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS
Sbjct: 1681 LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS 1740

Query: 1741 APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS 1800
            APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS
Sbjct: 1741 APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS 1800

Query: 1801 SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1833
            SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI
Sbjct: 1801 SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1833


>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
            sapiens]
          Length = 1723

 Score = 3298 bits (8551), Expect = 0.0
 Identities = 1623/1836 (88%), Positives = 1637/1836 (89%), Gaps = 116/1836 (6%)

Query: 1    MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60
            MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP
Sbjct: 1    MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60

Query: 61   SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120
            SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG
Sbjct: 61   SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120

Query: 121  GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
            GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS
Sbjct: 121  GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180

Query: 181  PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
            PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG
Sbjct: 181  PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240

Query: 241  KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300
            KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS
Sbjct: 241  KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300

Query: 301  NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360
            NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS
Sbjct: 301  NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360

Query: 361  GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420
            GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG
Sbjct: 361  GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420

Query: 421  SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480
            SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST
Sbjct: 421  SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480

Query: 481  GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540
            GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN
Sbjct: 481  GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540

Query: 541  QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600
            QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC
Sbjct: 541  QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600

Query: 601  QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660
            QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT
Sbjct: 601  QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660

Query: 661  KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720
            KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS
Sbjct: 661  KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720

Query: 721  SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
            SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI
Sbjct: 721  SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780

Query: 781  GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
            GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASG  
Sbjct: 781  GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASG-- 838

Query: 841  GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900
                            SW  GP P  P +  PS                    S+W    
Sbjct: 839  ----------------SWG-GPPPPPPGNVRPSN-------------------SSWSS-- 860

Query: 901  SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNE--- 957
                            GP P  P    P   +  S  S S     D+GTSAWG+PN    
Sbjct: 861  ----------------GPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904

Query: 958  SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEED 1017
             +    + +  G       N P    +    +SKSMQDGWGESDGPVTGARHPSWEEEED
Sbjct: 905  KNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEED 964

Query: 1018 GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTED 1077
            GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTED
Sbjct: 965  GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTED 1024

Query: 1078 NPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK 1137
            NPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK
Sbjct: 1025 NPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK 1084

Query: 1138 LTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGS 1197
                     G  G+    S    +P   L+ S S                          
Sbjct: 1085 -----GGSHGLFGNSTAQSRGLHTPVQPLNSSPS-------------------------- 1113

Query: 1198 HGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNV 1257
                         L   V P   SP + A             SMLKQFPNSGLSPGLFNV
Sbjct: 1114 -------------LRAQVPPQFISPQVSA-------------SMLKQFPNSGLSPGLFNV 1147

Query: 1258 GPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV 1317
            GPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV
Sbjct: 1148 GPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV 1207

Query: 1318 SALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSS 1377
            SALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSS
Sbjct: 1208 SALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSS 1267

Query: 1378 GGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQF 1437
            GGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQF
Sbjct: 1268 GGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQF 1327

Query: 1438 DIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESD 1497
            DIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESD
Sbjct: 1328 DIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESD 1387

Query: 1498 PYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHS 1557
            PYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHS
Sbjct: 1388 PYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHS 1447

Query: 1558 TSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSST 1617
            TSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSST
Sbjct: 1448 TSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSST 1507

Query: 1618 APRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTF 1677
            APRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTF
Sbjct: 1508 APRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTF 1567

Query: 1678 HLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAA 1737
            HLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAA
Sbjct: 1568 HLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAA 1627

Query: 1738 TPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPN 1797
            TPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPN
Sbjct: 1628 TPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPN 1687

Query: 1798 YSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1833
            YSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI
Sbjct: 1688 YSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1723


>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
            sapiens]
          Length = 1029

 Score = 1644 bits (4256), Expect = 0.0
 Identities = 811/903 (89%), Positives = 816/903 (90%), Gaps = 57/903 (6%)

Query: 931  SKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS 990
            S +A VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS
Sbjct: 184  SGTAPVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNS 243

Query: 991  KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 1050
            KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL
Sbjct: 244  KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 303

Query: 1051 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 1110
            KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI
Sbjct: 304  KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 363

Query: 1111 MRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSG 1170
            MRKDRSGFRPPNSKDMGTTDSGPYFEK         G  G+    S    +P   L+ S 
Sbjct: 364  MRKDRSGFRPPNSKDMGTTDSGPYFEK-----GGSHGLFGNSTAQSRGLHTPVQPLNSSP 418

Query: 1171 STLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP 1230
            S                                       L   V P   SP + A    
Sbjct: 419  S---------------------------------------LRAQVPPQFISPQVSA---- 435

Query: 1231 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 1290
                     SMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ
Sbjct: 436  ---------SMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 486

Query: 1291 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 1350
            QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM
Sbjct: 487  QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 546

Query: 1351 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 1410
            VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA
Sbjct: 547  VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 606

Query: 1411 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 1470
            TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK
Sbjct: 607  TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 666

Query: 1471 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 1530
            SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN
Sbjct: 667  SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 726

Query: 1531 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 1590
            SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI
Sbjct: 727  SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 786

Query: 1591 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 1650
            SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL
Sbjct: 787  SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 846

Query: 1651 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 1710
            VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN
Sbjct: 847  VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 906

Query: 1711 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 1770
            TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST
Sbjct: 907  TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 966

Query: 1771 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1830
            GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS
Sbjct: 967  GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1026

Query: 1831 DSI 1833
            DSI
Sbjct: 1027 DSI 1029



 Score =  325 bits (833), Expect = 2e-88
 Identities = 185/302 (61%), Positives = 206/302 (68%), Gaps = 33/302 (10%)

Query: 2   REKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 61
           +EKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS
Sbjct: 38  QEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 97

Query: 62  PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 121
           PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG
Sbjct: 98  PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 157

Query: 122 AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSP 181
           AGPPPCTAPGANPNNAQVTGALLQSESGTAP  +     A +   S WG    S+ G   
Sbjct: 158 AGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG--- 214

Query: 182 NPIHIWDKVIVDGSDMEEW---PCIASKDTESSSENTTDN--------NSASNPGSEKST 230
                W ++   G+    W   P  A    + +S++  D           A +P  E+  
Sbjct: 215 -----WGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEE 269

Query: 231 LPG--STTSNKGKGSQCQSASSGN------ECNLGVWKSD----PKAKSVQSSN--STTE 276
             G  +TT ++G  S   SAS G       +C+L    +D    P AK   +    S TE
Sbjct: 270 DGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTE 329

Query: 277 NN 278
           +N
Sbjct: 330 DN 331



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 27/122 (22%)

Query: 633 VWDIEEVPRPE------GKSDKGTEGWESAATQTKNSGGWGDAPS--------QSNQMKS 678
           VW     P P+      G+ ++ + GW        ++ GWG+ P+         S  M+ 
Sbjct: 189 VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQD 248

Query: 679 GWGELSAST------EWKDPKNTGGWN------DYKNNNSSNWG-GGRPDEKTPSSWNEN 725
           GWGE            W++ ++ G WN         ++NS++WG GG+   K       N
Sbjct: 249 GWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNN 308

Query: 726 PS 727
            S
Sbjct: 309 DS 310



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 9/111 (8%)

Query: 684 SASTEWKDPKNTG-GWNDYKNNNSSNWGGGRPDEKTPSSWNENP-SKDQGWGGGRQPNQG 741
           + ++ W +P  +  GW +  +  +S  G G      P++   N  S   GWG    P  G
Sbjct: 200 NGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTG 259

Query: 742 WSSGKNGWGEEVD----QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
             +    W EE D     T  S   +S+    S WG+GG+ ++     GGN
Sbjct: 260 --ARHPSWEEEEDGGVWNTTGSQGSASSHNSAS-WGQGGKKQMKCSLKGGN 307



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 68/308 (22%), Positives = 101/308 (32%), Gaps = 54/308 (17%)

Query: 670 PSQSNQMKSGWGELSASTEWKDPKN---TGGWNDYKNNNSSNWGGGRPD--EKTPSSWNE 724
           P     +  G G    +    +P N   TG     ++  +  W    P   +   S+W E
Sbjct: 148 PPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGE 207

Query: 725 NPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWG 784
                 GWG     + G S+   GWG       N+   +S S    GWGE          
Sbjct: 208 PNESSPGWG--EMDDTGAST--TGWGNTPANAPNAMKPNSKSMQ-DGWGE---------- 252

Query: 785 NGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPP 844
           + G  + A    WE+ +    WN TG Q ++ +                  AS   GG  
Sbjct: 253 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN---------------SASWGQGGKK 297

Query: 845 PPPPGNVRPSNSSWS-------SGPQPATPKDEEPSGWEEPSPQSIS-RKMDIDDGTSAW 896
                    +N SW        S     +  ++ PS   + S  S+S +K D+D      
Sbjct: 298 QMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNL 357

Query: 897 GDPNSYNYKNVNLWDKNSQGGPAPREPNLPT----PMTSKSASVWSKSTPPAPDNGTSAW 952
           GD N       ++  K+  G   P   ++ T    P   K  S        A   G    
Sbjct: 358 GDFN-------DIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTP 410

Query: 953 GEPNESSP 960
            +P  SSP
Sbjct: 411 VQPLNSSP 418



 Score = 32.0 bits (71), Expect = 5.7
 Identities = 39/160 (24%), Positives = 60/160 (37%), Gaps = 7/160 (4%)

Query: 295 PGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG 354
           P  G  N +P S+P   P  V  GT+    ++TD  +   + +T G  S    S      
Sbjct: 681 PWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTD--HQLLRDNTTGSNSSLNTSLPSPGA 738

Query: 355 VNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNP--MENKGMPFGMGLGNTSRSTDAP 410
             +  S      +H+T    P   +T S +    NP  + NK     +   NT+     P
Sbjct: 739 WPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPP 798

Query: 411 SQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNG 450
              T + K  S  S  A R   G  T   +  S +  ++G
Sbjct: 799 PGLT-NPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 837


>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
          Length = 1962

 Score = 1100 bits (2846), Expect = 0.0
 Identities = 776/2038 (38%), Positives = 1039/2038 (50%), Gaps = 308/2038 (15%)

Query: 7    EREEQLMEDKKRKKEDKKKKEATQK-VTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN 65
            + EEQLME+KK+KK+DKKKKEA QK  TEQK KVPE  KPS+SQP  A+   +  S   +
Sbjct: 22   QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANS-NNGTSTATS 80

Query: 66   GGNNAKRVAVPNGQP------------------------------PSAARYMPREVPPRF 95
              NNAKR    N QP                              P A    PREVPPRF
Sbjct: 81   TNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRF 140

Query: 96   RCQQDHKVLLKRGQPPPPSCMLLGGGA------GPPPCTAPGANPNNAQVTGALLQSESG 149
            R  Q+HK LLKRGQ  P     LG                     NN +V  +  QS+  
Sbjct: 141  R-HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDIN 199

Query: 150  TAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTE 209
                ST G    S+Y NS  G  +S    TS +  +  + V+ D S+ E WP     D E
Sbjct: 200  ---HSTSG----SHYENSQRGPVSS----TSDSSTNCKNAVVSDLSEKEAWPSAPGSDPE 248

Query: 210  SSSENTTDNNSAS--------------NPGSEKSTLPGSTTSNKGKGSQ------CQSAS 249
             +SE   D +SAS              N G EK  L  ST    G GSQ        S +
Sbjct: 249  LASE-CMDADSASSSESERNITIMASGNTGGEKDGLRNST----GLGSQNKFVVGSSSNN 303

Query: 250  SGNECNLGVWKSDPKA------KSVQSSNSTTE-NNNGLGNWRNVSGQDRIGPGSGFSNF 302
             G+  + G W     A       SV +  S +E +NN +  W  VS       G   S  
Sbjct: 304  VGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSS--NGGLNPSTL 361

Query: 303  NPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQT-------------------- 342
            N  SN  AWP L   G + KG + + +S  + Q ST+GQ                     
Sbjct: 362  NSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWG 421

Query: 343  SREQQSKMENAGVNFV-VSGREQAQIHNTDGPKNGNTNSLNLSSPN---------PMENK 392
            S ++  + E +G   V  SG+ Q       GP N  TN +  S PN         P  N 
Sbjct: 422  SLQETCESEVSGTQKVSFSGQPQNITTEMTGP-NNTTNFMTSSLPNSGSVQNNELPSSNT 480

Query: 393  G-----------MPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQS 441
            G           M    G+  TS S      S G+ K+G  GS+G   G  G    S  S
Sbjct: 481  GAWRVSTMNHPQMQAPSGMNGTSLS----HLSNGESKSG--GSYGTTWGAYG----SNYS 530

Query: 442  NSGNNGNNGKEREDSWKGASVQKS-TGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGN 500
                +G NG+   D+     +Q    G    ++  N    GG W  G  +S    WG GN
Sbjct: 531  GDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGN 590

Query: 501  KMTSGVSQGEWKQP---TGSDELKIGEWSG-PNQPNSS----------TGAWDN--QKGH 544
               SG S+  W  P   TG++ L   EW+  P+  +S+          T  W +  ++  
Sbjct: 591  GANSGGSRRGWGTPAQNTGTN-LPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQ 649

Query: 545  PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604
                +Q N Q+  W ++  +  S+   +STG   + G+ +S +  RR       D   +L
Sbjct: 650  GSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKI-----DQHTLL 704

Query: 605  QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664
            Q++++RTDLDPRVLSN+GWGQT IKQ+T WD E  PR E K+D GTE W S+ATQT NSG
Sbjct: 705  QSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSG 764

Query: 665  GWGDAPS---QSNQMKSGWGELSASTEWKDPKNT---GGWNDYKNN----NSSNWGGGRP 714
               D  S         SGWG+   +  W D K +   GGW D         S+ WG  + 
Sbjct: 765  ACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKE 824

Query: 715  DEKTPSSWNENPSKDQGWGGGRQPNQGWS----------SGKNGWGEEVDQTKNSNWESS 764
            ++   ++WN++    QGWG G++ +QGWS          S  N WGE     K+S+  S 
Sbjct: 825  EK---AAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEA--NKKSSSGGSD 879

Query: 765  ASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKR---SPAWNETGRQPNS--WNKQ 819
            + + VSGW E G+    TWGN  N + +S  GW++  +   S  W +  +   S  W   
Sbjct: 880  SDRSVSGWNELGKTSSFTWGNNINPNNSS--GWDESSKPTPSQGWGDPPKSNQSLGWGDS 937

Query: 820  HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPS 879
             +    P      Q +  GSWG     PP   +P  + W  GP PA  K+EEP+GWEEPS
Sbjct: 938  SKPVSSPDW--NKQQDIVGSWG----IPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPS 991

Query: 880  PQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREP-----NLPTP---MTS 931
            P+SI RKM+IDDGTSAWGDP+ YNYKNVN+W+KN   G +  +       L TP   +++
Sbjct: 992  PESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISN 1051

Query: 932  KSAS-------VWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANA 982
            K AS        W + + PA   DNGTSAWG+P +S P WGE     +ST+ WG++    
Sbjct: 1052 KEASSGSGWGEPWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGP 1111

Query: 983  PNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDG--GVWNTTGSQGSASSHN------ 1034
                K   KSMQDGW   D P+ G R   WEEEED   G+WN+  SQ   SS N      
Sbjct: 1112 QALSKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTK 1171

Query: 1035 -SASWGQGGKKQM--KCSLKGGN--NDSWMNPLAKQFSNMGLL--SQTEDNPSSKMDLSV 1087
              +S G  GKK+   +  +KGGN   ++W+NP  KQFSN+     S  E+  S+KMDLS 
Sbjct: 1172 KMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSG 1231

Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147
            G L DK+ ++DK ++N+GD+N  + K   G RP  SK+  + +  PYF+K        DG
Sbjct: 1232 GMLQDKRMEIDKHSLNIGDYNRTVGKG-PGSRPQISKE-SSMERNPYFDK--------DG 1281

Query: 1148 CLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQGGSHGLF--GNS 1204
             + DE+    F  S S KL PS S LPN +LG+I  GL  QN  + RQ G+  +F  GN+
Sbjct: 1282 IVADESQNMQFMSSQSMKLPPSNSALPNQALGSI-AGLGMQNLNSVRQNGNPSMFGVGNT 1340

Query: 1205 TAQSRGL-HTPVQPLNSS-PSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLS 1262
             AQ RG+   P QPL+SS P+LRAQVPP  +SPQV  S+LK  PN+G       + P   
Sbjct: 1341 AAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG------GLNPLFG 1394

Query: 1263 PQQIAMLSQLPQIPQFQLACQL--LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320
            PQQ+AML+QL Q+ Q     QL  LL QQQ+    Q+QR +    R QQ+QQ  R +S  
Sbjct: 1395 PQQVAMLNQLSQLNQLSQISQLQRLLAQQQR---AQSQRSVPSGNRPQQDQQ-GRPLSVQ 1450

Query: 1321 QQQQQQ----------QQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIP- 1369
            QQ  QQ          +Q+ P  +  P H    K  LDN++P+      P+LQ KGP P 
Sbjct: 1451 QQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHT----TPELQ-KGPSPI 1505

Query: 1370 ----GYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAP 1425
                 +  G +S  ++  M        +SR ++WT+ ++ +    + + N  K+GAI + 
Sbjct: 1506 NAFSNFPIGLNS-NLNVNMDMNSIKEPQSRLRKWTT-VDSISVNTSLDQNSSKHGAI-SS 1562

Query: 1426 GKTRGGSPYNQFDIIPGDTL-GGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGV 1484
            G     SP+  +D +   T      G  GD W  AKSP      + SS+ +WPPEF+PG 
Sbjct: 1563 GFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSP------NGSSSVNWPPEFRPGE 1616

Query: 1485 PWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWP 1544
            PWKG  NIDPE+DPYVTPGSV+   + + + + DH  LRD  +GS+SSLNT+LPS  AW 
Sbjct: 1617 PWKGYPNIDPETDPYVTPGSVINNLSINTVREVDH--LRDRNSGSSSSLNTTLPSTSAWS 1674

Query: 1545 YSASDN----SFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPR 1600
               + N      +   STSA+  D K TWSP  + +  T L++++WK  +  +N T   R
Sbjct: 1675 SIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTN--TSLAHELWKVPLPPKNITAPSR 1732

Query: 1601 PPPGLTNPKPS-SPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQI 1659
            PPPGLT  KP  S W ++  R   GWG  D+R    S+W +  S R + WLVL NLTPQI
Sbjct: 1733 PPPGLTGQKPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQI 1792

Query: 1660 DGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFAT 1719
            DGSTLRT+CMQHGPL+TFHLNL  G AL+RYS+K+E  KAQ +LHMCVLGNTTILAEFA+
Sbjct: 1793 DGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFAS 1852

Query: 1720 DDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSA 1779
            ++E+SRF AQ+Q  T       P+ GWQSL + Q++   +    + F   T L  W+ + 
Sbjct: 1853 EEEISRFFAQSQSLT-------PSPGWQSLGSSQSRLGSL-DCSHSFSSRTDLNHWNGAG 1904

Query: 1780 -GGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPL---LPGDLLGGGSDSI 1833
              G++  DL G SLWG P+YS+SLWG P+  DP  + SP+P+   L  D LGGG +S+
Sbjct: 1905 LSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962


>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
            sapiens]
          Length = 1726

 Score =  920 bits (2378), Expect = 0.0
 Identities = 686/1820 (37%), Positives = 887/1820 (48%), Gaps = 305/1820 (16%)

Query: 208  TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267
            T+ ++ N   N +     S +S L     ++ G  ++    ++G+   L          S
Sbjct: 14   TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66

Query: 268  VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
            V   +   +   G G  +N  G      G    N NPN+NP+AWP L  EGT   G    
Sbjct: 67   VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121

Query: 328  DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370
            + S+  + VS +GQ    Q                 +S       +  VS   Q Q  NT
Sbjct: 122  NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181

Query: 371  DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415
            DGP N  TN +N SSPNP+         N GM  GMG        G    +  + SQ +G
Sbjct: 182  DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238

Query: 416  DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474
                G   S WG + G   T    G SNSG +  NG    D+   A   K  GS   S  
Sbjct: 239  GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288

Query: 475  NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530
                S G +W+ GP        WG G  N     +  G W  P+ S    + GEW  P  
Sbjct: 289  QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346

Query: 531  PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578
            PN  + +  N KG      P   +Q     P       W +++SS  +   G S GS NH
Sbjct: 347  PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406

Query: 579  KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
              GS+    +G    R      Q  +Q  L R DLDPRVLSNTGWGQT +KQ+T W+ EE
Sbjct: 407  NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464

Query: 639  VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690
             PR E K+D GTE W  AATQ  NSGG  D     S +    SGW       + A+T W 
Sbjct: 465  SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524

Query: 691  D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734
            D     P   G W D  ++ + +          W G    E    +W E P  K Q WG 
Sbjct: 525  DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584

Query: 735  GRQPNQGWSSGKNGWGEEV-------DQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786
            G++ N  WS+G   W +         D  KN S W++ +++  SGW +  ++    WGN 
Sbjct: 585  GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644

Query: 787  GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845
             N        W E  K  P  N   +                    PQ     +WGG   
Sbjct: 645  TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGGA-- 682

Query: 846  PPPGNVRPSNSSWSSGPQPATPKDE-EPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904
                +V+ + + W  GP P   KD  E +GWEEPSP SI RKM+IDDGTSAWGDP++YN 
Sbjct: 683  ---ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739

Query: 905  KNVNLWDKNSQGGPAPREPNLPTPMT---------------------------------- 930
            K VN+WD+N+    +    N  T  T                                  
Sbjct: 740  KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSG 799

Query: 931  --------SKSASVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPA 980
                    SK+ + W + + P+   DNGT+AWG+P  S  GWG+         G    P 
Sbjct: 800  WGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPV 859

Query: 981  NAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQ 1040
             A    KP SKSMQ+GWG S G         WE+EE G VWN   SQ S SS   +SWG 
Sbjct: 860  AASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSSWGN 915

Query: 1041 GGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSLSDK 1093
              KK ++  +K  G  +++W M+ L KQ ++MG   +  +      +  +D ++ +L +K
Sbjct: 916  APKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEK 975

Query: 1094 KFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEA 1153
            K DVDKR + + D N +  K   G RPP SK+  + D   + +K        DG L +E 
Sbjct: 976  KVDVDKRGLGVTDHNGMAAKPL-GCRPPISKE-SSVDRPTFLDK--------DGGLVEEP 1025

Query: 1154 PCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQ--GGSHGLFGNS-TAQSR 1209
              SPF PSPS KL  S S LP+ +LG I +GL  QN  ++RQ   G+ G+FGNS  AQ+R
Sbjct: 1026 TPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQAR 1085

Query: 1210 GLHTP----VQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQLSP 1263
             +  P    VQPLNSS PSLRAQVP QF+SPQV A +L+    N GL+P L      ++P
Sbjct: 1086 TMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLT--SPINP 1142

Query: 1264 QQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQ 1323
            Q + ML+QL Q+   QLA Q L   Q QQQ+LQ QR +S ++RQQ EQQ+AR ++ LQQQ
Sbjct: 1143 QHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMRQQ-EQQVARTITNLQQQ 1195

Query: 1324 QQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG---- 1366
             QQ QRQ             P   H   HP   K  +D+   +    GLPDLQTK     
Sbjct: 1196 IQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS 1255

Query: 1367 -------PIPGYGSGFSSGGMDYGMVGGKE----AGTESRFKQWT--SMMEGLPSVATQ- 1412
                   P+ G     +   MD  M GG      + ++SR  QWT  + M+ LPS A+  
Sbjct: 1256 PNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPL 1313

Query: 1413 EANMHKNGAIVA------PGKTRGGSPYNQFDIIPGDTLGGHTGPA-GDSWLPAKSPPTN 1465
            E N  K+GAI        PGK+     Y ++D+I           A   SW  AKS  ++
Sbjct: 1314 EQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSD-SD 1372

Query: 1466 KIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQLLRD 1524
            KI S  S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV  G T  + I D +  LL+ 
Sbjct: 1373 KI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKS 1431

Query: 1525 NTTGSNSSLNTSLPSPGAWP-----YSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPT 1579
              +   SS N +LPS  AWP     YS+S +S  +  S + K  D KSTWS  P  H   
Sbjct: 1432 GGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQA 1491

Query: 1580 HLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWS 1639
             LS+++WK     RN+T   RPPPGLTNPKPSS W +    S  GW    S  +S S WS
Sbjct: 1492 SLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWS 1541

Query: 1640 DGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKA 1699
               S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKA
Sbjct: 1542 TDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKA 1601

Query: 1700 QTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPV 1759
            Q +LHMCVLGNTTILAEFA ++EV+RFLAQ Q     A P  P + WQS           
Sbjct: 1602 QKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ----- 1649

Query: 1760 GPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHR 1813
             P L+  G S GL     G W++   G  G   +   LW G P YSSSLWG P+ +D   
Sbjct: 1650 -PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRV 1705

Query: 1814 MGSPAP---LLPGDLLGGGS 1830
            +GSP P   LLPGDLL G S
Sbjct: 1706 IGSPTPLTTLLPGDLLSGES 1725



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 96/497 (19%), Positives = 178/497 (35%), Gaps = 86/497 (17%)

Query: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186
           C A  A+ +  +  G+++ S + ++    +    A+  AN+ WG     +N  +P+   +
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536

Query: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
           W   I                W   A+++ +S +        + + G  + + P  +   
Sbjct: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594

Query: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293
            G G    S+S        + N   W +D        +++T   N+G GN  N       
Sbjct: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649

Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344
                    NP +N   W   ++ G  +  A +  ++N S     ++V QT         
Sbjct: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697

Query: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396
             +Q+   E  G         + ++   DG      P N N  ++N+   N   N  +  
Sbjct: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754

Query: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454
                 T+ +T   S +T   +T      G    R P      SG    G   N   + E
Sbjct: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGW---GEMPNVHSKTE 811

Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
           +SW G     ST   N           G+  +G   S+ + WG+ +     V+ G    P
Sbjct: 812 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 858

Query: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563
                     S  ++ G  SG ++ N ST  W++++G   +     +  +    WG ++ 
Sbjct: 859 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 917

Query: 564 STGSEVGGQSTGSNHKA 580
             G + G +++G   +A
Sbjct: 918 KKGLQKGMKTSGKQDEA 934


>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
            sapiens]
          Length = 1690

 Score =  882 bits (2280), Expect = 0.0
 Identities = 672/1818 (36%), Positives = 868/1818 (47%), Gaps = 337/1818 (18%)

Query: 208  TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267
            T+ ++ N   N +     S +S L     ++ G  ++    ++G+   L          S
Sbjct: 14   TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66

Query: 268  VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
            V   +   +   G G  +N  G      G    N NPN+NP+AWP L  EGT   G    
Sbjct: 67   VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121

Query: 328  DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370
            + S+  + VS +GQ    Q                 +S       +  VS   Q Q  NT
Sbjct: 122  NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181

Query: 371  DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415
            DGP N  TN +N SSPNP+         N GM  GMG        G    +  + SQ +G
Sbjct: 182  DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238

Query: 416  DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474
                G   S WG + G   T    G SNSG +  NG    D+   A   K  GS   S  
Sbjct: 239  GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288

Query: 475  NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530
                S G +W+ GP        WG G  N     +  G W  P+ S    + GEW  P  
Sbjct: 289  QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346

Query: 531  PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578
            PN  + +  N KG      P   +Q     P       W +++SS  +   G S GS NH
Sbjct: 347  PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406

Query: 579  KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
              GS+    +G    R      Q  +Q  L R DLDPRVLSNTGWGQT +KQ+T W+ EE
Sbjct: 407  NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464

Query: 639  VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690
             PR E K+D GTE W  AATQ  NSGG  D     S +    SGW       + A+T W 
Sbjct: 465  SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524

Query: 691  D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734
            D     P   G W D  ++ + +          W G    E    +W E P  K Q WG 
Sbjct: 525  DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584

Query: 735  GRQPNQGWSSGKNGWGEEV-------DQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786
            G++ N  WS+G   W +         D  KN S W++ +++  SGW +  ++    WGN 
Sbjct: 585  GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644

Query: 787  GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845
             N        W E  K  P  N   +                    PQ     +WGG   
Sbjct: 645  TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGGA-- 682

Query: 846  PPPGNVRPSNSSWSSGPQPATPKDE-EPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904
                +V+ + + W  GP P   KD  E +GWEEPSP SI RKM+IDDGTSAWGDP++YN 
Sbjct: 683  ---ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739

Query: 905  KNVNLWDKNSQGGPAPREPNLPTPMT---------------------------------- 930
            K VN+WD+N+    +    N  T  T                                  
Sbjct: 740  KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKV 799

Query: 931  -----------SKSASVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGN 977
                       SK+ + W + + P+   DNGT+AWG+P  S  GWG+         G   
Sbjct: 800  SSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAG 859

Query: 978  TPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSAS 1037
             P  A    KP SKSMQ+GWG S G         WE+EE G VWN   SQ S SS   +S
Sbjct: 860  APVAASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSS 915

Query: 1038 WGQGGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSL 1090
            WG   KK ++  +K  G  +++W M+ L KQ ++MG   +  +      +  +D ++ +L
Sbjct: 916  WGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSAL 975

Query: 1091 SDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLG 1150
             +KK DVDKR + + D N +  K   G RPP SK+  + D   + +K        DG L 
Sbjct: 976  LEKKVDVDKRGLGVTDHNGMAAKPL-GCRPPISKE-SSVDRPTFLDK--------DGGLV 1025

Query: 1151 DEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQ--GGSHGLFGNS-TA 1206
            +E   SPF PSPS KL  S S LP+ +LG I +GL  QN  ++RQ   G+ G+FGNS  A
Sbjct: 1026 EEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAA 1085

Query: 1207 QSRGLHTP----VQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQ 1260
            Q+R +  P    VQPLNSS PSLRAQVP QF+SPQV A +L+    N GL+P L      
Sbjct: 1086 QARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLT--SP 1142

Query: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320
            ++PQ + ML+QL Q+   QLA Q L   Q QQQ+LQ QR +S ++RQQ EQQ+AR ++ L
Sbjct: 1143 INPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMRQQ-EQQVARTITNL 1195

Query: 1321 QQQQQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG- 1366
            QQQ QQ QRQ             P   H   HP   K  +D+   +    GLPDLQTK  
Sbjct: 1196 QQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQ 1255

Query: 1367 ----------PIPGYGSGFSSGGMDYGMVGGKE----AGTESRFKQWT--SMMEGLPSVA 1410
                      P+ G     +   MD  M GG      + ++SR  QWT  + M+ LPS A
Sbjct: 1256 QSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAA 1313

Query: 1411 TQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIPGDTLGGHTGPA-GDSWLPAKSP 1462
            +  E N  K+GAI        PGK+     Y ++D+I           A   SW  AKS 
Sbjct: 1314 SPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSD 1373

Query: 1463 PTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQL 1521
             ++KI S  S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV  G T  + I D +  L
Sbjct: 1374 -SDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYL 1431

Query: 1522 LRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHL 1581
            L+                                  +  K  D KSTWS  P  H    L
Sbjct: 1432 LK----------------------------------SGGKLSDIKSTWSSGPTSHTQASL 1457

Query: 1582 SNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 1641
            S+++WK     RN+T   RPPPGLTNPKPSS W +    S  GW    S  +S S WS  
Sbjct: 1458 SHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWSTD 1507

Query: 1642 GSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQT 1701
             S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKAQ 
Sbjct: 1508 TSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQK 1567

Query: 1702 ALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGP 1761
            +LHMCVLGNTTILAEFA ++EV+RFLAQ Q     A P  P + WQS            P
Sbjct: 1568 SLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ------P 1614

Query: 1762 ALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHRMG 1815
             L+  G S GL     G W++   G  G   +   LW G P YSSSLWG P+ +D   +G
Sbjct: 1615 RLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRVIG 1671

Query: 1816 SPAP---LLPGDLLGGGS 1830
            SP P   LLPGDLL G S
Sbjct: 1672 SPTPLTTLLPGDLLSGES 1689



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 95/497 (19%), Positives = 177/497 (35%), Gaps = 83/497 (16%)

Query: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186
           C A  A+ +  +  G+++ S + ++    +    A+  AN+ WG     +N  +P+   +
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536

Query: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
           W   I                W   A+++ +S +        + + G  + + P  +   
Sbjct: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594

Query: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293
            G G    S+S        + N   W +D        +++T   N+G GN  N       
Sbjct: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649

Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344
                    NP +N   W   ++ G  +  A +  ++N S     ++V QT         
Sbjct: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697

Query: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396
             +Q+   E  G         + ++   DG      P N N  ++N+   N   N  +  
Sbjct: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754

Query: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454
                 T+ +T   S +T   +T      G    R P         S  G   N   + E
Sbjct: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTE 814

Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
           +SW G     ST   N           G+  +G   S+ + WG+ +     V+ G    P
Sbjct: 815 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 861

Query: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563
                     S  ++ G  SG ++ N ST  W++++G   +     +  +    WG ++ 
Sbjct: 862 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 920

Query: 564 STGSEVGGQSTGSNHKA 580
             G + G +++G   +A
Sbjct: 921 KKGLQKGMKTSGKQDEA 937


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score =  102 bits (254), Expect = 3e-21
 Identities = 152/827 (18%), Positives = 299/827 (36%), Gaps = 40/827 (4%)

Query: 146  SESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIAS 205
            S+S  A D      + +N ++S  G+G   NNG   N      K   D SD +      S
Sbjct: 505  SDSKGAEDDDSDSTSDTNNSDSN-GNG---NNGNDDNDKSDSGKGKSDSSDSDSSDSSNS 560

Query: 206  KDTESSSEN-TTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
             D+  SS++ ++D+NS+S+  S  S    S+ S+    S    +S  ++ +     SD  
Sbjct: 561  SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD-- 618

Query: 265  AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGA 324
            +   +S +S +E+++   + ++ S        S  S+ + +SN S          S   +
Sbjct: 619  SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678

Query: 325  LETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLS 384
              +D+SNSS    +   ++  + S              + +   ++D   + N+NS +  
Sbjct: 679  SSSDSSNSSDSSDSSDSSNSSESS-----------DSSDSSDSDSSDSSDSSNSNSSDSD 727

Query: 385  SPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSG 444
            S N  ++          ++S S+++   S     + S  S  ++     +D  S  S+  
Sbjct: 728  SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD--SSNSSDS 785

Query: 445  NNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTS 504
            N+ +N  +  DS   +    S+ S + S  +++ S+  S +    DS+D+     +  +S
Sbjct: 786  NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845

Query: 505  GVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSS 564
              S        GSD          N  +SS  +  +        +  N  +     S SS
Sbjct: 846  DSSD-------GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898

Query: 565  TGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWG 624
              S+    S+ S++ + SSDS NS   S      D      +  S    D    SN+   
Sbjct: 899  NSSD--SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956

Query: 625  QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684
                      D  +       SD       S ++ + +S    D+   SN   S   + S
Sbjct: 957  SNSSDSSNSSDSSD----SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS--SDSS 1010

Query: 685  ASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSS 744
             S++  +  ++   +D  N++ S+      D    S  +++             +   SS
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070

Query: 745  GKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSP 804
              +   +  D +++S+   S++   S       +   +  +  ++  +      D   S 
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130

Query: 805  AWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQP 864
              +++    NS +     +           ++S S          +   SNSS SS    
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD--SSNSSDSSDSSD 1188

Query: 865  ATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPN 924
            ++   +     +       S   D  D + +    +S +  + N   ++S    +    +
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN---ESSDSSDSSDSSD 1245

Query: 925  LPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGAS 971
                  S  +S  S ST  + D   S     N ++ G     D+  S
Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292



 Score =  102 bits (254), Expect = 3e-21
 Identities = 141/792 (17%), Positives = 280/792 (35%), Gaps = 46/792 (5%)

Query: 133  NPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192
            N NN         S  G +  S    + +SN ++S+  S + S++  S +     D    
Sbjct: 529  NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588

Query: 193  DGSDMEEWPCIASKDTESSSE--NTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASS 250
            D SD +      S D+  SS+  +++D++ +S+  S+ S     ++ +  K     S SS
Sbjct: 589  DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648

Query: 251  GNECNLGVWKSDPKAKSVQSSNST-TENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPS 309
             +  N     S   + S  SS+S+ + +++   +  N S        S  S  + +S+ S
Sbjct: 649  DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708

Query: 310  AWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHN 369
               +     +S   + ++D+SNSS    +   +     S   N+  +   S    +   +
Sbjct: 709  DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768

Query: 370  TDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAAR 429
                 + +++S N S  N              N+S S+D+ + S     + S  S  ++ 
Sbjct: 769  DSSDSSDSSDSSNSSDSNDS-----------SNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817

Query: 430  GPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQ 489
              S   + S  S+  ++ +N  +  DS   +    S  S      N++ S+  S +    
Sbjct: 818  SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877

Query: 490  DSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPEN 549
            DS+D+   + N+ ++     +    + SD     + S  +  + S+ + D+ +     +N
Sbjct: 878  DSSDS--SDSNESSNSSDSSDSSNSSDSDS---SDSSNSSDSSDSSNSSDSSESSNSSDN 932

Query: 550  QGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLS 609
              ++       SS+S+ S     S+ S+  + SSDS NS   S                 
Sbjct: 933  SNSSD------SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS----------------D 970

Query: 610  RTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDA 669
                D    SN+             D  +       SD       S ++ + NS    ++
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030

Query: 670  PSQSNQM-KSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSK 728
               S+    S   + S S++  D  N+   +D  +++ S+      D    S  +++   
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090

Query: 729  DQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
                      +   SS  +   +  D + +SN   S+    S       N   +  +  +
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150

Query: 789  ASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPP 848
            +  +      D   S   +++    +S N                 ++S S         
Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1210

Query: 849  GNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQS----ISRKMDIDDGTSAWGDPNSYNY 904
             +   S+ S  S     +    E S   + S  S     S   D  D + +  D N  + 
Sbjct: 1211 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD 1270

Query: 905  KNVNLWDKNSQG 916
                  + N+ G
Sbjct: 1271 SQSKSGNGNNNG 1282



 Score =  100 bits (250), Expect = 1e-20
 Identities = 133/680 (19%), Positives = 262/680 (38%), Gaps = 57/680 (8%)

Query: 133  NPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192
            N +++  + +   S+S  + DS+   +++S+ +NS+  S +S ++ +S +          
Sbjct: 653  NSDSSDSSNSSNSSDSSDSSDSS-DSSSSSDSSNSSDSSDSSDSSNSSESS--------- 702

Query: 193  DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGN 252
            D SD  +    +S  ++SS+ N++D++S+++  S  S+    ++ +    +   S+ S +
Sbjct: 703  DSSDSSDSD--SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760

Query: 253  ECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWP 312
              N     SD    S  S +S + N++   +  N S        S  SN + +S+ S   
Sbjct: 761  SSN----SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS--- 813

Query: 313  ALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDG 372
                + +    +  +D+SNSS   S    +S    S   + G +   S R  +  +++D 
Sbjct: 814  ----DSSDSDSSNSSDSSNSS-DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS-NSSDS 867

Query: 373  PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPS 432
              + ++++ + SS +   N+         N+S S+D+ + S  D    S  S  +    S
Sbjct: 868  SDSSDSSNSSDSSDSSDSNES-------SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920

Query: 433  GTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKN--------DSWDNNNRSTGGSW 484
               + S  S+  +N ++     DS   +    S+ S N        DS D+N+  +  S 
Sbjct: 921  SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980

Query: 485  NFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH 544
            N      + +     +   S  S         SD     + S  +  ++S+ + D+    
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 545  PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604
               ++  ++ +     SS S+ S     S+ S+  + SSDS  S   S      D     
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100

Query: 605  QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664
             +  S    D    S++             D  +       SD       S ++ + +S 
Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160

Query: 665  GWGDAPSQSNQM-------------KSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGG 711
               D+   S+                S   + S S++  D  ++   +D  +++ S+   
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220

Query: 712  GRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWES-SASKPVS 770
               D    S  NE+             N   SS  +   +  D T +SN ES S SK  +
Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSN---SSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277

Query: 771  GWGEGGQNEIGTWGNGGNAS 790
            G   G  ++  + G+  N S
Sbjct: 1278 GNNNGSDSDSDSEGSDSNHS 1297



 Score = 98.2 bits (243), Expect = 6e-20
 Identities = 112/616 (18%), Positives = 233/616 (37%), Gaps = 28/616 (4%)

Query: 146  SESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIAS 205
            S+S  + +S    + +SN ++S+  S +S ++ +S +          D S+  +    + 
Sbjct: 713  SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772

Query: 206  KDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLG-VWKSDPK 264
                S S N++D+N +SN      +   S +SN    S    +S  +  N      S   
Sbjct: 773  SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832

Query: 265  AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGA 324
            + S  SS+S+  +++  G+  + S +      S  S+ + +SN S          S   +
Sbjct: 833  SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892

Query: 325  LETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLS 384
              +D+SNSS   S+    S +      ++         + ++  N+    N + +S +  
Sbjct: 893  DSSDSSNSSDSDSSDSSNSSDSSDSSNSS---------DSSESSNSSDNSNSSDSSNSSD 943

Query: 385  SPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSG 444
            S +  ++          ++S S+D+   ++ D    S  S  +    S   + S  S++ 
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003

Query: 445  NNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTS 504
            ++ ++  +  DS   +    S+ S N S  +++  +  S +      + +     +   S
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063

Query: 505  GVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSS 564
              S         SD     E S  +  ++S+ + D+       ++  ++ +     SS+S
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123

Query: 565  TGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWG 624
            + S     S+ S+  + SSDS +S   S      D      +  S    D    SN+   
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-- 1181

Query: 625  QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684
                      D  +       SD       S ++ + +S    D+   S+   S   + S
Sbjct: 1182 ----------DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS--SDSS 1229

Query: 685  ASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSS 744
             S E  D  ++   +D  N++ S+       + + S+ + N   D     G   N G  S
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSS----DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285

Query: 745  GKNGWGEEVDQTKNSN 760
              +  G + + + + +
Sbjct: 1286 DSDSEGSDSNHSTSDD 1301



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 161/894 (18%), Positives = 320/894 (35%), Gaps = 54/894 (6%)

Query: 145  QSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIA 204
            +S  G  P+S+   +  ++ ANS   + +SS    S N     D    +GSD        
Sbjct: 458  KSMQGDDPNSS-DESNGNDDANSESDNNSSSRGDASYNSDESKDNG--NGSD-------- 506

Query: 205  SKDTESS-SENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263
            SK  E   S++T+D N++ + G+  +    +  S+ GKG    S S  ++ +     SD 
Sbjct: 507  SKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDS 566

Query: 264  KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323
                   SNS++++++   +  + S  D     S  SN + +S+ S              
Sbjct: 567  SDSDSSDSNSSSDSDSSDSDSSDSSDSD----SSDSSNSSDSSDSS-------------- 608

Query: 324  ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL 383
                D+S+SS   S+    S+   SK E+   +   S  + +  +++D   N +++  + 
Sbjct: 609  ----DSSDSSD--SSDSSDSKSDSSKSESDSSD-SDSKSDSSDSNSSDSSDNSDSSDSSN 661

Query: 384  SSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNS 443
            SS +   +          ++  S  + S  + D    S  S  +    S +   S  SNS
Sbjct: 662  SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721

Query: 444  GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMT 503
             ++ ++     DS   ++   S+ S + S  +++  +  S N      + +     +   
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781

Query: 504  SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSS 563
            S  S         SD     + S  +  + S+ + D+   +    +  +  +     S S
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 564  STGSEVG-GQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTG 622
            S  S+   G  + S++++ SS+S +S   S      D      +  S    D    SN+ 
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 623  WGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGE 682
               +    ++  D  +       S+       S ++ + NS    D+   SN   S    
Sbjct: 902  DSDSSDSSNSS-DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960

Query: 683  LSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGW 742
             S+++      N+   +D  N++ S+      D    S  + +             N   
Sbjct: 961  DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020

Query: 743  SSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKR 802
            SS  +      D + +S+   S+    S       N   +  +  ++  +      D   
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080

Query: 803  SPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGP 862
            S   +++    NS +                 ++S S          +   S+ S  S  
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140

Query: 863  QPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPRE 922
               +    E S   + S  S S   D  D + +    +S N  + +    +S    +   
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDS--SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198

Query: 923  PNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANA 982
             +      S  +S  S S+  +  + +S   + NESS      D + +S +   +  ++ 
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD- 1257

Query: 983  PNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSA 1036
                  +S S  D   ESD               + G  + + S+GS S+H+++
Sbjct: 1258 ------SSDSTSDSNDESDSQSKSG------NGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 148/856 (17%), Positives = 298/856 (34%), Gaps = 40/856 (4%)

Query: 207  DTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAK 266
            D  +SS+ +  N+ A++     S+  G  + N       +S  +GN        SD K  
Sbjct: 463  DDPNSSDESNGNDDANSESDNNSSSRGDASYNSD-----ESKDNGNG-------SDSKGA 510

Query: 267  SVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALE 326
                S+ST++ NN   N    +G D           + +S+  +  +     +S     +
Sbjct: 511  EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570

Query: 327  TDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSP 386
            + +SNSS+   +    S +      +   N   S        ++D   + ++ S +  S 
Sbjct: 571  SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 387  NPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNN 446
            +   +          N+S S+D    S     + S  S  ++   S + + S  SNS ++
Sbjct: 631  SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS-SDSSSSSDSSNSSDS 689

Query: 447  GNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506
             ++      S    S   S    +DS D++N ++  S +    DS+D+     N   S  
Sbjct: 690  SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS----NSSDSSD 745

Query: 507  SQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTG 566
            S         SD       S  +  + S+ + D+       ++  ++ +     SS S+ 
Sbjct: 746  SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805

Query: 567  SEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQT 626
            S     S+ S+     SDS NS   S      D      +  S    D     ++    +
Sbjct: 806  SSDSSDSSDSS----DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861

Query: 627  QIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSAS 686
                D+  D  +       SD       S ++ + +S    D+ S  +   S   + S S
Sbjct: 862  SNSSDSS-DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920

Query: 687  TEWKDPKNTGGWNDYKNNNSSNWGGGRPD-----EKTPSSWNENPSKDQGWGGGRQPNQG 741
            ++  +  N+   ++  ++++S+      D     + + SS + N S           +  
Sbjct: 921  SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980

Query: 742  WSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCK 801
             SS  +   +  D + +S+  +S+    S       N   +  +  +++ +      D  
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 802  RSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSG 861
             S   +++    +S N                 ++S S          +   SNSS SS 
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD--SSNSSDSSD 1098

Query: 862  PQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPR 921
               ++   +     +       S   D  D + +    +S N         +S    +  
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN---------SSDSSDSSE 1149

Query: 922  EPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPAN 981
              +      S  +S  S S+  +  + +S   + ++SS      D + +S +   ++  +
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS--SDSSDS 1207

Query: 982  APNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQG 1041
            + ++   +S    D    SD   +     S +  +     N++ S  S+ S +S S    
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267

Query: 1042 GKKQMKCSLKGGNNDS 1057
                   S  G NN S
Sbjct: 1268 ESDSQSKSGNGNNNGS 1283



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 171/945 (18%), Positives = 322/945 (34%), Gaps = 47/945 (4%)

Query: 207  DTESSSENTTDNNSASNPGSEK---STLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263
            D +SS    +D+    +P  ++   + + G  TS   + S      +G++      K + 
Sbjct: 290  DHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNH 349

Query: 264  KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323
            +      +  T E+           G +  GP SG  N               EG   KG
Sbjct: 350  RESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKG------NEGKEDKG 403

Query: 324  --ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSL 381
               +     N   Q   V      Q+S+  N      V         N+DG  + + +  
Sbjct: 404  QHGMILGKGNVKTQGEVVNIEGPGQKSEPGNK-----VGHSNTGSDSNSDGYDSYDFDDK 458

Query: 382  NLSSPNPME----NKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTV 437
            ++   +P      N          N S S    S ++ + K    GS         +D+ 
Sbjct: 459  SMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518

Query: 438  SGQSNS-----GNNGNNGKEREDSWKGASVQKSTGS-----KNDSWDNNNRSTGGSWNFG 487
            S  +NS     GNNGN+  ++ DS KG S    + S      +DS D+++  +  S +  
Sbjct: 519  SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578

Query: 488  PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
              DS+D+   + +   S  S         SD     + S  +   S +   ++       
Sbjct: 579  DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD--S 636

Query: 548  ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTL 607
            +++ ++       SS ++ S     S+ S+  + SSDS +S   S      D      + 
Sbjct: 637  DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696

Query: 608  LSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWG 667
             S    D    S++    +    ++     +       SD       S ++ + NS    
Sbjct: 697  NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756

Query: 668  DAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPS 727
            D+   SN   S   + S S++  D  N+   ND  N++ S+       + + SS + N S
Sbjct: 757  DSSDSSNSSDS--SDSSDSSDSSDSSNSSDSNDSSNSSDSS-------DSSNSSDSSNSS 807

Query: 728  KDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGG 787
                       +   SS  +   +  D + NS+  S +S    G      N   +  +  
Sbjct: 808  DSSDSSDSSDSDSSNSSDSSNSSDSSD-SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 788  NASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP 847
            ++  +      D   S   NE+    +S +  +               +  S        
Sbjct: 867  SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926

Query: 848  PGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNV 907
              +   SNSS SS    ++   +  +  +  +    S   D  D  S+    +S N  + 
Sbjct: 927  SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS-DSSDSSNSSDS 985

Query: 908  NLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDD 967
            +    +S    +    N      S  +S  S S+  +  + +S   + ++SS      D 
Sbjct: 986  SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045

Query: 968  TGAS-TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS 1026
            + +S ++   N+  ++ ++   +S    D    SD   +     S    +     +++ S
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105

Query: 1027 QGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLS 1086
              S+ S +S+            S    ++DS  +  +   S+    S + D+  S     
Sbjct: 1106 SDSSDSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164

Query: 1087 VGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDS 1131
                SD     D  + N  D +D      S     +S    ++DS
Sbjct: 1165 SSDSSDSSDSSD--SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 171/957 (17%), Positives = 322/957 (33%), Gaps = 113/957 (11%)

Query: 184  IHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGS 243
            + + D++   G+  E    +   D     ENT D +     GS+ + + G + S      
Sbjct: 42   VSVQDELNASGTIKESGVLVHEGD-RGRQENTQDGHKGEGNGSKWAEVGGKSFST----- 95

Query: 244  QCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGL-GNWRNVSGQDRIGPGSGFSNF 302
               S  +  E N+  W  D       +  + T  ++G+ G   N++     G  S   N 
Sbjct: 96   --YSTLANEEGNIEGWNGD-------TGKAETYGHDGIHGKEENITANGIQGQVSIIDN- 145

Query: 303  NPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGR 362
                                GA    N+N +   +T       Q   + +AG N      
Sbjct: 146  -------------------AGATNRSNTNGNTDKNT-------QNGDVGDAGHN------ 173

Query: 363  EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSV 422
            E   +   DGP+   +N+   +    +EN         GNTS  T   +      K   V
Sbjct: 174  EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCR----NEGNTSEITPQINSKRNGTKEAEV 229

Query: 423  GSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGG 482
                     +G D     S+   +GN   E ED   G    +  G+  DS  NN++   G
Sbjct: 230  TPG------TGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDS-SNNSKGQEG 282

Query: 483  SWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQK 542
              + G +D +D+  G+ +         E+  P G ++         N+ +    +   + 
Sbjct: 283  Q-DHGKEDDHDSSIGQNS------DSKEYYDPEGKED-------PHNEVDGDKTSKSEEN 328

Query: 543  GHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQA 602
               +PE+ G+ +     + +      V  + T  +       S + G     P+  +   
Sbjct: 329  SAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNI 388

Query: 603  VLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKN 662
              +        + +       G+  +K  T  ++  +  P  KS+ G +   S      N
Sbjct: 389  TKEVGKGNEGKEDKGQHGMILGKGNVK--TQGEVVNIEGPGQKSEPGNKVGHSNTGSDSN 446

Query: 663  SGGWGDAPSQSNQMKSGWGELSASTEWKDPKNT--GGWNDYKNNNSSNWGGGRPDEKTPS 720
            S G+         M+             DP ++     ND  N+ S N    R D    +
Sbjct: 447  SDGYDSYDFDDKSMQG-----------DDPNSSDESNGNDDANSESDNNSSSRGD----A 491

Query: 721  SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
            S+N + SKD G G         S  K    ++ D T ++N   S     +G G  G ++ 
Sbjct: 492  SYNSDESKDNGNG---------SDSKGAEDDDSDSTSDTNNSDS-----NGNGNNGNDDN 537

Query: 781  GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
                +G   S +S     D   S   +++    +S +                 ++  S 
Sbjct: 538  DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597

Query: 841  GGPPPPPPGNVRPSNSSWSS----GPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAW 896
                     +   S+SS SS        ++  + + S  +  S  S S   D  D + + 
Sbjct: 598  SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657

Query: 897  GDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPN 956
               NS N  + +    +S    +    N      S  +S  S+S+  +  + + +    +
Sbjct: 658  DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717

Query: 957  ESSPGWGEMDDTGAS-TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEE 1015
             S+    + D + +S ++   N+  ++ ++   NS    D    S+   +     S +  
Sbjct: 718  SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 1016 EDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQT 1075
            +     ++  S  S+ S +S++                ++    N      S+    S  
Sbjct: 778  DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 1076 EDNPSSKMDLSVGSLSDKKFDVD-KRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDS 1131
              + S   D S GS SD     D   + +  D +D      S     +++   ++DS
Sbjct: 838  SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 255/1186 (21%), Positives = 412/1186 (34%), Gaps = 190/1186 (16%)

Query: 119  GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178
            G G+G  P  + G + +    + +  Q  SG+   S+ G   + +  +S +G   S +  
Sbjct: 1236 GSGSGHSP--SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1293

Query: 179  TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
            +S    H        GS    + C   +   +S +++T +   S+ G   S     + S+
Sbjct: 1294 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344

Query: 239  KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297
            +  G     A SG   + G   S        S +S++   +G G+ W + SG  R G GS
Sbjct: 1345 QSSGYGRHGAGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 1395

Query: 298  GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354
            G S+   +   S+W +    G ++ G+    +S+     S  GQ+SR ++   S   ++ 
Sbjct: 1396 GQSSGFGHHESSSWQS---SGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 1452

Query: 355  VNFVVSGREQAQIHNTDGPKNGNTNSLNLS---SPNPMENKGMPFGMGLGNTS-----RS 406
                 SG  Q+  H   G  +G + S +     S +   +   P+G G G +S      S
Sbjct: 1453 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYES 1512

Query: 407  TDAPSQSTGDRKTGS-----VGSWGAARGPSGTD----TVSGQSNS-------------- 443
              + S   G R++ S      G  G++ G S T     + SGQS+S              
Sbjct: 1513 GSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1572

Query: 444  -----GNNGNNGKEREDSWKGASV---QKSTGSKND-SWDNNNRSTGGSWNFGPQDS--- 491
                 G++ ++G  R+ S  G S    Q+ +GS+   S+  +   +G S + G   S   
Sbjct: 1573 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1632

Query: 492  -------NDNKWGEGNKMT-----SGVSQGEWKQPTGSDELKIGEWSGPNQPNSST---- 535
                   +++  G+ +  +     SG S G  +  + S +   GE  G +  +SS     
Sbjct: 1633 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQH 1692

Query: 536  GAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRP 595
            G+   Q      +  G+ Q+P  GR     GS +G  S+   H +GS  S + G    R 
Sbjct: 1693 GSGSRQSSGHGRQGSGSGQSPSRGRH----GSGLGHSSSHGQHGSGSGRSSSRGPYESRS 1748

Query: 596  THPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIK------QDTVWDIEEVPRPEGKSDKG 649
             H       ++    +    +  S +G   +Q +      Q + +D +E       S  G
Sbjct: 1749 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD-QEGSSTGQSSSHG 1807

Query: 650  TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNW 709
              G  S ++Q+ + G  G    QS            S+ +    +  GW+     + S  
Sbjct: 1808 QHG--SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865

Query: 710  GGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKP 768
            G          SSW  +     G G G       SS     G    Q+       S+S  
Sbjct: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGH------SSSYEQHGSRSGQSSRGEQHGSSSGS 1919

Query: 769  VSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ 828
             S +G+ G     + G+G + S                  +G+ P+    +H        
Sbjct: 1920 SSSYGQHGSGSRQSLGHGQHGS-----------------GSGQSPSPSRGRHGSGSGQSS 1962

Query: 829  PPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMD 888
               P    SG W     P       S S  SSG      +  + SG+ +    S      
Sbjct: 1963 SYGPYGSGSG-WSSSRGP-----YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2016

Query: 889  IDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWS-------KST 941
               G SA G  +S      +    +S G                S S  S         +
Sbjct: 2017 GQHG-SASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075

Query: 942  PPAPDNGTSAWGEPNESS-----PGWGEMDDTG---------ASTTGWGNTPANAPNAMK 987
              +P  G    G    SS     PG GE    G         +S +  G+   ++    +
Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135

Query: 988  PNSKSMQDGWGESDGPVTGA-----RHPSWEEEEDG--------GVWNTTGSQGSASSHN 1034
              S+S Q   GE  G  +G+     +H S   +  G        G   + G  GS S H 
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGH- 2194

Query: 1035 SASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV-GSLSDK 1093
            S+S GQ G         G    S   P   +  +  +  Q E         S  GS S  
Sbjct: 2195 SSSHGQHG--------SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246

Query: 1094 KFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEA 1153
                 +     G  +     D+ G     S   G   SG          S+Q    G + 
Sbjct: 2247 FCSQGQHGSTSGQSSTF---DQEGSSTGQSSSHGQHGSG----------SSQSSSYGQQG 2293

Query: 1154 PCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHG 1199
              S  SPS     S SG    + S G  G+G    + + R G   G
Sbjct: 2294 SGSGQSPSRGRHGSGSGH---SSSYGQHGSGSGWSSSSGRHGSGSG 2336



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 182/900 (20%), Positives = 309/900 (34%), Gaps = 131/900 (14%)

Query: 157  GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216
            G   + +Y     GSG SS++G               GS   +      K +   S   T
Sbjct: 899  GSGQSPSYGRHGSGSGRSSSSGRH-------------GSGSGQSSGFGHKSSSGQSSGYT 945

Query: 217  DNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTE 276
             + S S  G   S     + S +   S+   +SSG+  + G   S        S  S   
Sbjct: 946  QHGSGS--GHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSG-------SRQSLGH 996

Query: 277  NNNGLGNWRNVS-GQDRIGPGSG-FSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSA 334
              +G G+ ++ S  + R G GSG  S++ P  + S W       +S +G  E+ + +SS 
Sbjct: 997  GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW-------SSSRGPYESGSGHSS- 1048

Query: 335  QVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGM 394
                 G   RE +S  +++G     S    +  H   G  +G ++S            G 
Sbjct: 1049 -----GLGHRESRSG-QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG--------QHGA 1094

Query: 395  PFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKERE 454
              G    +    + + SQS+G  + GS        G  G+ +    S   +   +G+   
Sbjct: 1095 SSGQSSSHGQHGSGS-SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1153

Query: 455  DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
                G+ + +S+G     + ++  S+G       Q S+ ++ G G+  +SG  Q   +  
Sbjct: 1154 SGQHGSGLGESSG-----FGHHESSSG-------QSSSYSQHGSGSGHSSGYGQHGSRSG 1201

Query: 515  TGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQST 574
              S   + G  SG +      G+   Q      +  G+  +P  GR     GS +G  S+
Sbjct: 1202 QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRH----GSGLGHSSS 1257

Query: 575  GSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVW 634
               H +GS  S + G    R  H       ++    +    +  S +G   +Q +  +  
Sbjct: 1258 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317

Query: 635  DIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKS----GWGELSASTEWK 690
                    EG S   +  +    + +  S G+G   + S Q  S    G G    S+ + 
Sbjct: 1318 GQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS-GHSSSYG 1376

Query: 691  DPKNTGGWNDYKNNNSSNWGGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGW 749
               +  GW+     + S  G          SSW  +     G G G       SS     
Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGH------SSSYEQH 1430

Query: 750  GEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNET 809
            G    Q+       S+S   S +G+ G     + G+G + S                  +
Sbjct: 1431 GSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGS-----------------GS 1473

Query: 810  GRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKD 869
            G+ P+    +H           P    SG W     P       S SS SSG      + 
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSG-WSSSRGP-----YESGSSHSSGLGHRESRS 1527

Query: 870  EEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPM 929
             + SG+ +    S          +S  G   S + ++ +     +  G            
Sbjct: 1528 GQSSGYGQHGSSS--------GHSSTHGQHGSTSGQSSSCGQHGASSG------------ 1567

Query: 930  TSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPN 989
              +S+S     +  +  +G    G  +  SPG G+       +  +G     + +    +
Sbjct: 1568 --QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR--HGSGSGRSSS 1623

Query: 990  SKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 1049
            S     G GES G            E   G  ++    GS S H S+ +GQ G +  + S
Sbjct: 1624 SGQHGSGLGESSG--------FGHHESSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS 1674



 Score = 88.6 bits (218), Expect = 5e-17
 Identities = 207/1001 (20%), Positives = 351/1001 (35%), Gaps = 162/1001 (16%)

Query: 119  GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178
            G G+G  P  + G + +    + +  Q  SG+   S+ G   + +  +S +G   S +  
Sbjct: 1706 GSGSGQSP--SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1763

Query: 179  TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
            +S    H        GS    + C   +   +S +++T +   S+ G   S     + S+
Sbjct: 1764 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 1814

Query: 239  KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297
            +      Q + SG   + G   S        S +S++   +G G+ W + SG  R G GS
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 1865

Query: 298  GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354
            G S+   +   S+W +    G ++ G+    +S+     S  GQ+SR +Q   S   ++ 
Sbjct: 1866 GQSSGFGHHESSSWQS---SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSS 1922

Query: 355  VNFVVSGREQAQIHNTDGPKNGNTNSLNLS---SPNPMENKGMPFGMGLGNTSRSTDAPS 411
                 SG  Q+  H   G  +G + S +     S +   +   P+G G G +S      S
Sbjct: 1923 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYES 1982

Query: 412  ----------------QSTGDRKTGSV-------GSWGAARGPS----------GTDTVS 438
                            QS+G  + GS        G  G+A G S          G  +  
Sbjct: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042

Query: 439  GQSNSGNNGNNGKEREDSWKGASV---QKSTGSKND-SWDNNNRSTGGSWNFGP------ 488
            GQ  SG++ ++G  R+ S  G S    Q+ +GS+   S+  +   +G S + G       
Sbjct: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102

Query: 489  -------------QDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSST 535
                         Q S+ ++ G G+  +SG  Q   +    S   + G  SG +      
Sbjct: 2103 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQH 2162

Query: 536  GAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRP 595
            G+   Q      +  G+  +P  GR     GS  G  S+   H +GS  S + G    R 
Sbjct: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRH----GSGSGHSSSHGQHGSGSGRSSSRGPYESRS 2218

Query: 596  THPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIK------QDTVWDIEEVPRPEGKSDKG 649
             H       ++    +    +  S +G   +Q +      Q + +D +E       S  G
Sbjct: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD-QEGSSTGQSSSHG 2277

Query: 650  TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNW 709
              G  S ++Q+ + G  G    QS            S+ +    +  GW+     + S  
Sbjct: 2278 QHG--SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335

Query: 710  GGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKP 768
            G          SSW  +     G G G       SS     G    Q+       S+S  
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGH------SSSYEQHGSRSGQSSRGERHGSSSGS 2389

Query: 769  VSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ 828
             S +G+ G     + G+G + S                  +G+ P+    +H        
Sbjct: 2390 SSSYGQHGSGSRQSLGHGQHGS-----------------GSGQSPSPSRGRHGSGSGQSS 2432

Query: 829  PPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMD 888
               P    SG W     P       S S  SSG      +  + SG+ +    S      
Sbjct: 2433 SYSPYGSGSG-WSSSRGP-----YESGSGHSSGLGHRESRSGQSSGYGQHGSSS------ 2480

Query: 889  IDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNG 948
                +S  G   S + ++ +     +  G              +S+S     +  +  +G
Sbjct: 2481 --GHSSTHGQHGSTSGQSSSCGQHGASSG--------------QSSSHGQHGSGSSQSSG 2524

Query: 949  TSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGAR 1008
                G  +  SPG G+       +  +G     + +    +S     G GES G      
Sbjct: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGR--HGSGSGRSSSSGQHGSGLGESSG------ 2576

Query: 1009 HPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 1049
                  E   G  ++    GS S H S+ +GQ G +  + S
Sbjct: 2577 --FGHHESSSGQSSSYSQHGSGSGH-SSGYGQHGSRSGQSS 2614



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 206/930 (22%), Positives = 341/930 (36%), Gaps = 109/930 (11%)

Query: 162  SNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSA 221
            S++++S+W +G   N+  S N         V GS       I S+      + +  +NS 
Sbjct: 125  SSFSHSSWSAG--ENDSYSRN---------VRGSLKPGTESI-SRRLSFQRDFSGQHNSY 172

Query: 222  SNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP-KAKSVQSSNSTTENNNG 280
            S   S        +  + G+G QC S S G   N G   S   ++ S  +  S +  ++G
Sbjct: 173  SGQSSSYGEQNSDSHQSSGRG-QCGSGS-GQSPNYGQHGSGSGQSSSNDTHGSGSGQSSG 230

Query: 281  LGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPAL--VQEGTSRKGALETDNSNSSAQVST 338
                ++ SGQ      SG+S     S  S+       + G S +G     +S SS+    
Sbjct: 231  FSQHKSSSGQS-----SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285

Query: 339  VGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL--SSPNPMENKGMPF 396
             G  SR+      + G     SG  Q+  H   G  +G+++S     S  +   ++G  +
Sbjct: 286  HGSGSRQ------SLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGH-Y 338

Query: 397  GMGLGNTS---RSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQ-SNSGNNGNNGKE 452
              G G TS   +      QS+G  K GS     +++G  G+   SGQ S+SG +G++ ++
Sbjct: 339  ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS--TSGQASSSGQHGSSSRQ 396

Query: 453  REDSWKGASVQKSTGSKNDSWDNNNRSTG----GSWNFGPQDSNDNKWGEGNKMTSG--V 506
                 +  S  + +  +      + +S G    GS +     S  +  G G   +SG  V
Sbjct: 397  SSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYV 456

Query: 507  SQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQ---GNAQAPCWGRSSS 563
            S   +    G  E      SG  Q  S +G       H     Q   G  Q    G SSS
Sbjct: 457  SGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAG-SSS 515

Query: 564  STGSEVGG--QSTG-SNHKAGSSDS-------HNSGRRSYRPTHPDCQAVLQTLLSRTDL 613
            S G    G  QS G S H +GS  S       H SG R      P      ++  SR   
Sbjct: 516  SYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSS-SRGPY 574

Query: 614  DPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDK-GTEGWESAATQTKNSGGWGDAPSQ 672
            +     ++G G  + +        +     G S   G  G  S + Q+ + G  G    Q
Sbjct: 575  ESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG--STSGQSSSCGQHGATSGQ 632

Query: 673  SNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGW 732
            S+         S S+ +    +  G +  +  + S++G         SS+ ++ S   GW
Sbjct: 633  SSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHS-------SSYGQHGS-GSGW 684

Query: 733  GGGRQPNQGWSSGKNGWGEEVDQTKNSNWES--SASKPVSGWGEGGQNEIGTWGNGGNAS 790
                 P+   S   +G+G +    ++S +    S S   SG+ + G          G +S
Sbjct: 685  SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRS-------GQSS 737

Query: 791  LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGN 850
             + + G      S ++ + G   +  +   +Q       P      S S         G+
Sbjct: 738  RSEQHG-SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS 796

Query: 851  VRPSNSS---WSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNV 907
                +SS   + SG   A+   +  SG    S Q  S+        S+ G   S + ++ 
Sbjct: 797  GTSCSSSCGHYESGSGQASGFGQHESG----SGQGYSQHGSASGHFSSQGRHGSTSGQSS 852

Query: 908  NLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDD 967
            +    +S  G              +S+S     +     +G    G  +  SPG G+   
Sbjct: 853  SSGQHDSSSG--------------QSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG- 897

Query: 968  TGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQ 1027
                 +G G +P+   +       S     G   G  +G  H S   +  G   + +GS 
Sbjct: 898  -----SGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSG 952

Query: 1028 GSAS--SHNSASWGQGGKKQMKCSLKGGNN 1055
             S+S   H S S GQ  + +   S  G ++
Sbjct: 953  HSSSYEQHGSRS-GQSSRSEQHGSSSGSSS 981



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 191/995 (19%), Positives = 333/995 (33%), Gaps = 183/995 (18%)

Query: 157  GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216
            G   + NY     GSG SS+N T              GS   +    +   + S   +  
Sbjct: 198  GSGQSPNYGQHGSGSGQSSSNDT-------------HGSGSGQSSGFSQHKSSSGQSSGY 244

Query: 217  DNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS----------SGNECNLGVWKSDPKAK 266
              + + +  S      GS +    +G + +S+S          SG+  +LG  +    ++
Sbjct: 245  SQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSR 304

Query: 267  SVQ--------SSNSTTENNNGLGNWRNVS-GQDRIGPG--SGFSNFNPNSNPSAWPALV 315
                       S +S++   +G G+  + S G    G G  SGF      S  S+  +  
Sbjct: 305  QSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKH 364

Query: 316  QEGTSRKGALETDNSNSSAQVSTVGQ---TSREQQSKMENAGVNFVVSGREQAQIHNTDG 372
              G+    + +  + ++S Q S+ GQ   +SR+  S  ++   +   SGR Q    +   
Sbjct: 365  GSGSGHSSS-QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQS 423

Query: 373  PKNGNTNSLNLSSPNPMEN--------------KGMPFGMGLGNTSRSTDAPS----QST 414
            P +G   S +  SP+  ++               G  +  G G+   S++  S      +
Sbjct: 424  PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483

Query: 415  GDRKTGSVGSWGAARGPS----------GTDTVSGQSNSGNNGNNGKEREDSWKGASVQK 464
            G   +   G  G+  G S          G+ +  GQ  SG+  + G  R  S  G S   
Sbjct: 484  GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543

Query: 465  STG------SKNDSWDNNNRSTGGSWNFGPQDS-NDNKWGEGNKMT-SGVSQGEWKQPTG 516
            S G       ++ S+  +   +G S + GP +S + +  G G++ + SG S G  +  + 
Sbjct: 544  SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSS 603

Query: 517  SDELKI-----------------GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWG 559
            S                      G  SG +  +   G+  +Q      +  G+ Q+P  G
Sbjct: 604  SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRG 663

Query: 560  RSSSSTG---------------------SEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHP 598
            R  S  G                       V GQS+G  HK+GS  S    +     +H 
Sbjct: 664  RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH- 722

Query: 599  DCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAAT 658
                                 ++G+                 R  G     +   E   +
Sbjct: 723  ---------------------SSGY-----------------RKHGSRSGQSSRSEQHGS 744

Query: 659  QTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKT 718
             +  S  +G   S S+Q  SG G   + +     +   G +   +++    G G     +
Sbjct: 745  SSGLSSSYGQHGSGSHQ-SSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803

Query: 719  PSSWNENPSKDQGWGGGRQ-PNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQ 777
               +     +  G+G       QG+S   +  G    Q ++ +    +S   SG  +   
Sbjct: 804  CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS--SGQHDSSS 861

Query: 778  NEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ----PPPPQ 833
             +  ++G   +AS  + G      R    + +G+ P    +     Q P          +
Sbjct: 862  GQSSSYGQHESASHHASG------RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGR 915

Query: 834  PEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGT 893
              +SG  G       G    S+S  SSG           S +E+   +S         G+
Sbjct: 916  SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGS 975

Query: 894  SAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWG 953
            S+ G  +SY             G         P+P   +  S   +S+   P    S W 
Sbjct: 976  SS-GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034

Query: 954  E---PNES----SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTG 1006
                P ES    S G G  +     ++G+G   +++ ++          G   S G    
Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG---- 1090

Query: 1007 ARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQG 1041
                  +     G  ++ G  GS SS +S    QG
Sbjct: 1091 ------QHGASSGQSSSHGQHGSGSSQSSGYGRQG 1119



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 162/727 (22%), Positives = 271/727 (37%), Gaps = 126/727 (17%)

Query: 119  GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178
            G G+G  P  + G + + +  + +  Q  SG+   S+ G   + +  +S +G   S +  
Sbjct: 2176 GSGSGHSP--SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233

Query: 179  TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
            +S    H        GS    + C   +   +S +++T +   S+ G   S     + S+
Sbjct: 2234 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 2284

Query: 239  KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297
            +      Q + SG   + G   S        S +S++   +G G+ W + SG  R G GS
Sbjct: 2285 QSSSYGQQGSGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 2335

Query: 298  GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354
            G S+   +   S+W +    G ++ G+    +S+     S  GQ+SR ++   S   ++ 
Sbjct: 2336 GQSSGFGHHESSSWQS---SGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 2392

Query: 355  VNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQST 414
                 SG  Q+  H   G  +G        SP+P   +    G G G          QS+
Sbjct: 2393 YGQHGSGSRQSLGHGQHGSGSGQ-------SPSPSRGR---HGSGSG----------QSS 2432

Query: 415  GDRKTGSVGSWGAARGP----SGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKN 470
                 GS   W ++RGP    SG  +  G   S +  ++G  +  S  G S   ST  ++
Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS---STHGQH 2489

Query: 471  DSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530
             S    + S G       Q S+  + G G+  +SG      +Q +GS     G+  G  Q
Sbjct: 2490 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG----RQGSGS-----GQSPGHGQ 2540

Query: 531  PNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHN--- 587
              S                 G+ Q+P +GR  S +G        GS     S   H+   
Sbjct: 2541 RGS-----------------GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 2583

Query: 588  SGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSD 647
            SG+ S    H                      ++G+GQ   +       E      G S 
Sbjct: 2584 SGQSSSYSQHGSGSG----------------HSSGYGQHGSRSGQSSRGERHGSSSGSSS 2627

Query: 648  K-GTEGWESAATQTKNSGGWGDAPSQS-NQMKSGWGELSASTEWKDPKNTG-----GWND 700
              G  G  S + Q+   G  G    QS ++ + G G   +S+  +    +G     G  +
Sbjct: 2628 HYGQHG--SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 2685

Query: 701  YKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSN 760
             +  +SS +G         S+++++     G G G   +QG     +G     DQ  +S 
Sbjct: 2686 SRLGHSSVFGQHESGSGHSSAYSQH-----GSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740

Query: 761  WESSA-------SKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQP 813
             +SS+       S   SG+G  G       G+G + S    G       S   + +G   
Sbjct: 2741 GQSSSYGHRGSGSSQSSGYGRHGA------GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQ 2794

Query: 814  NSWNKQH 820
            +S   QH
Sbjct: 2795 SSGYSQH 2801



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 211/1029 (20%), Positives = 355/1029 (34%), Gaps = 156/1029 (15%)

Query: 147  ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
            ESG+   S LG   + +  +S +G   SS+  +S +  H         +  +   C    
Sbjct: 575  ESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH-------GSTSGQSSSCGQHG 627

Query: 207  DTESSSENTTDNNSASNPGS---EKSTLPGSTTSNKGKGSQCQSASSGNECNLGV-WKSD 262
             T   S +   + S S+  S   ++ +  G + S    GS    +SS  +   G  W S 
Sbjct: 628  ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS- 686

Query: 263  PKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRK 322
                S     S +  ++G G+ ++ SGQ      SG+S     S+ S+       G  + 
Sbjct: 687  ----SNGPHGSVSGQSSGFGH-KSGSGQS-----SGYSQHGSGSSHSS-------GYRKH 729

Query: 323  GALETDNSNSSAQVSTVGQTSREQQS-----KMENAGVNFVVSGREQAQI-------HNT 370
            G+    +S S    S+ G +S   Q      +    G     SG   +++       H++
Sbjct: 730  GSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSS 789

Query: 371  DGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNT----------SRSTDAPSQSTGDRKTG 420
               ++G+  S + S  +     G   G G   +          S S    SQ      +G
Sbjct: 790  SHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSG 849

Query: 421  SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASV---QKSTGS-KNDSWDNN 476
               S G     SG  +  GQ  S ++  +G+ R  S  G S    Q+ +GS ++ S+  +
Sbjct: 850  QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909

Query: 477  NRSTGGSWNFGPQDSNDNKW-GEGNKMTSGVSQGEWKQPTGSDEL--------KIGEWSG 527
               +G S + G   S   +  G G+K +SG S G  +  +GS           + G+ S 
Sbjct: 910  GSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969

Query: 528  PNQPNSSTGAWDNQKGHPLPENQ---------GNAQAPCWGRSSSSTGSEVGGQSTGSNH 578
              Q  SS+G+  +   H     Q         G+ Q+P   R    +GS  G  S+   +
Sbjct: 970  SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS--GQSSSYGPY 1027

Query: 579  KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
            ++GS  S + G       H       ++   ++    +  S++G   T  +  +      
Sbjct: 1028 RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1087

Query: 639  VPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGW 698
                 G S   +       + +  S G+G   S S Q   G G+  + +         G 
Sbjct: 1088 SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ-SPGHGQRGSGSRQSPSYGRHGS 1146

Query: 699  NDYKNNNSSNWGGGRPDEK-----TPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEV 753
               ++++S   G G  +         SS   +     G G G     G    ++G     
Sbjct: 1147 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206

Query: 754  DQTKNSNWES-------SASKPVSGWGEGGQN-----EIGTWGNG------------GNA 789
            ++  +S+  S       S S+  SG G  G         G  G+G            G+ 
Sbjct: 1207 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSG 1266

Query: 790  SLASKGGWED--------------CKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPE 835
              +S+G +E                  S A+++ G     +  Q Q      Q      E
Sbjct: 1267 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1326

Query: 836  ASGSWGGPPPPPPGNVRPSNSSWSSG-PQPATPKDEEPSGWEEPSPQSISRKMDIDDGTS 894
             S +            R S SS SSG  +      + PS     S    S         S
Sbjct: 1327 GSST----GQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGS 1382

Query: 895  AW-----------GDPNSYNYKNVNLWDKN--SQGGPAPREPNLPTPMTSKSASVWSKST 941
             W           G  + + +   + W  +  +Q G      +      S+S       +
Sbjct: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSG-----QS 1437

Query: 942  PPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQ------- 994
                 +G+S+    +    G G     G    G G+  + +P+  +  S S Q       
Sbjct: 1438 SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY 1497

Query: 995  ---DGWGESDGPV-TGARHPS--WEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKC 1048
                GW  S GP  +G+ H S     E   G  +  G  GS+S H S++ GQ G    + 
Sbjct: 1498 GSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTSGQS 1556

Query: 1049 SLKGGNNDS 1057
            S  G +  S
Sbjct: 1557 SSCGQHGAS 1565


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 217/974 (22%), Positives = 316/974 (32%), Gaps = 164/974 (16%)

Query: 140  TGALLQSESGTAPDSTLGGAAASNYANSTW------GSGASSNNGTSPNPIHIWDKVIVD 193
            TG++       +   TL GA   N     W      G+G  +     P  +      ++ 
Sbjct: 877  TGSVQPQAVANSHCETLPGA--KNKVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLP 934

Query: 194  GSD--MEEWPCIASKDTESSSENTTDNNSASN-PGSEKSTLPGSTTSNKGKGSQCQSASS 250
            G+   ++  P + SK    + E+T  +        S++ TLPG+    KG  S   S + 
Sbjct: 935  GAKNKVKGNPNVVSK--AGAREDTVGSTQPQVLASSQRETLPGARNKVKGN-SNVVSKAG 991

Query: 251  GNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSA 310
              E  +G  +    A S Q        N   GN   +S  +    G+G          ++
Sbjct: 992  AREDTMGSAQPQVVANS-QRETLPGARNKVKGNSNAISKAEA---GAGIMGSVQVQVVAS 1047

Query: 311  WPALVQEGTSRKGALETDNSNS----SAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQ 366
            +   V  G   K      NSN+     A   TVG     Q   + N+    ++  R + +
Sbjct: 1048 FQGEVLPGAKNK---VRGNSNAVPKAEAGADTVGSA---QPQAVANSQSETLLGARNKVK 1101

Query: 367  IHNTDGPKNGN-TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGD----RKTGS 421
             +    PK G    + + + P  +         G  + S ST     +  D    +    
Sbjct: 1102 GNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAE 1161

Query: 422  VGSWGAARGPSGTDTV-SGQSNSGNNGNNGKERED-----SWKGASVQKSTGSKNDS--W 473
                  + G SGT      Q N  +   NG   ED      W     Q   G   +S  W
Sbjct: 1162 AMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWIKFRFQTMDGDWENSVSW 1221

Query: 474  -DNNNRSTGGSWNFGPQDSND--NKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530
             D+ N ++ GSW+ G  D       W      TS  S   W      + + IG W+   +
Sbjct: 1222 ADDENEASIGSWS-GASDKAGIIRSWAVACDETSVKS---WAGARAENVVGIGTWARAGE 1277

Query: 531  PNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGR 590
              +S G W            G      W    +S     GG  TG+ ++A       +G 
Sbjct: 1278 -QASGGLWAG----------GQTSEGTWAGDKAS-----GGAWTGAENQASGGSWALAGN 1321

Query: 591  RSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTV---WDIEEVPRPEGKSD 647
                      QA+ +   +    D         G + + ++ +   W   E    EG   
Sbjct: 1322 ----------QAIGELWAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWA 1371

Query: 648  KGTEG-------WESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWND 700
                G       W     Q    G W     QS        E  AS E       G W  
Sbjct: 1372 GAGAGNMSSVSYWAGVVDQA-GGGSWAGTSDQSGGGSKPRFEDQASGE-------GSWAG 1423

Query: 701  YKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSN 760
                 S     G  D+ +  SW +  + DQ  GG R  +   SSG   W   +DQ+    
Sbjct: 1424 AGGQASGGSMLGPEDQSSGRSWAD--TADQASGGSRLGHVDQSSG-GAWAGTLDQS---- 1476

Query: 761  WESSASKPVSGWGEGGQNEIGTW-GNGGNASLASKGGWEDCKRSPAWNETGRQPN----- 814
                 SKP     E    E G+W G GG A   SK G ED     +W  +G Q +     
Sbjct: 1477 --GGGSKPRF---ENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLV 1531

Query: 815  ---------SWNKQ-HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQP 864
                     SW    H     P+     Q    GSW        G+ R      SSG   
Sbjct: 1532 GIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSW 1591

Query: 865  ATPKDEEPSGW--EEPSPQSISRKMDIDDGTSAWGD-PNSYNYKNVNLWDKNSQGGPAPR 921
            A   D+  SGW    P  Q+         G    G  P   N  +   WD          
Sbjct: 1592 AGTGDQA-SGWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWD---------- 1640

Query: 922  EPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPG--W-GEMDDTGASTTGWGNT 978
                 +P +  S S W+ +       G S  G  +++  G  W G  D TG  +      
Sbjct: 1641 -----SPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGS------ 1689

Query: 979  PANAPNAMKPNSKSMQDG---WGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNS 1035
                    +P S+    G   WG + G V G   P   ++  GG W  TG+Q S      
Sbjct: 1690 --------RPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSS-----G 1736

Query: 1036 ASWGQGGKKQMKCS 1049
             SW   G + + CS
Sbjct: 1737 RSWIGPGDQAVDCS 1750



 Score = 74.7 bits (182), Expect = 8e-13
 Identities = 211/1009 (20%), Positives = 323/1009 (32%), Gaps = 171/1009 (16%)

Query: 107  RGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPD-------STLGGA 159
            RG   P +     G   P        NPN     GA   +   T P         TL GA
Sbjct: 917  RGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLPGA 976

Query: 160  AASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNN 219
                  NS   S A +   T  +        +V  S  E  P   +K   +S+  +    
Sbjct: 977  RNKVKGNSNVVSKAGAREDTMGSA----QPQVVANSQRETLPGARNKVKGNSNAISKAEA 1032

Query: 220  SASNPGS---------EKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
             A   GS         +   LPG+    +G  +    A +G +    V  + P+A +   
Sbjct: 1033 GAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADT---VGSAQPQAVANSQ 1089

Query: 271  SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALV--QEGTSRKGALETD 328
            S +     N +    N     + G G+G       +  SA P +V   +G +  GA +  
Sbjct: 1090 SETLLGARNKVKG--NTIAVPKAGTGAG-------TRHSAQPQIVAGSQGETLPGARDKS 1140

Query: 329  NSNSSAQVSTVGQTSREQQSKM-----ENAGVNFVVSGREQAQIH----NTDGPKNGNTN 379
             S S A+ +   +   + +++         G       + Q  IH    N  G ++    
Sbjct: 1141 MSTSEAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAA 1200

Query: 380  SLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG------------SVGSWGA 427
               +       +      +   +        S S    K G            SV SW  
Sbjct: 1201 ERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAG 1260

Query: 428  ARGPS----GTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDN-NNRSTGG 482
            AR  +    GT   +G+  SG     G+  E +W G    K++G    +W    N+++GG
Sbjct: 1261 ARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAG---DKASGG---AWTGAENQASGG 1314

Query: 483  SWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGE------WSGPNQPNSSTG 536
            SW      +    W  G       S G W     S    +GE      W+G     +S G
Sbjct: 1315 SWALAGNQAIGELWAAGQ-----ASDGSWPGGQASGVSWVGEEAIGGSWTGAEN-QASEG 1368

Query: 537  AWDNQKGHPLPENQGN-AQAPCWGRSSSSTGSEVGGQSTGSNHKAGSS-----DSHNSGR 590
            +W            GN +    W       G   GG   G++ ++G       +   SG 
Sbjct: 1369 SWAGA-------GAGNMSSVSYWAGVVDQAG---GGSWAGTSDQSGGGSKPRFEDQASGE 1418

Query: 591  RSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGT 650
             S+       QA   ++L   D      S   W  T  +      +  V +  G +  GT
Sbjct: 1419 GSWAGAGG--QASGGSMLGPEDQS----SGRSWADTADQASGGSRLGHVDQSSGGAWAGT 1472

Query: 651  EGWESAAT------QTKNSGGWGDAPSQSNQ-MKSGWGELSASTEWKDPKN--TGGW--N 699
                   +      QT   G W  A  Q+    K G  + S+   W +  +  +GG+   
Sbjct: 1473 LDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVG 1532

Query: 700  DYKNNNSSNW-GGGRPDEKTPSSWNENPSKDQG-WGGGRQPNQGWSS-GKNGWGEEVDQT 756
                 N  +W G G P    P    E+    +G W   R+   G S  G        DQ+
Sbjct: 1533 IVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLR------DQS 1586

Query: 757  KNSNWESSASKPVSGWG---EGGQNEIGTWGNGGNASLA-SKGGWEDCKRSPAWNETGRQ 812
               +W  +  +  SGW     G Q   G+WG      +  S+ G  +   + +W+  G Q
Sbjct: 1587 SGDSWAGTGDQ-ASGWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQ 1645

Query: 813  PNS--WNKQHQQQQPPQQPPP---PQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATP 867
             +   W       Q      P    Q    G W G      G  RP +   SSG      
Sbjct: 1646 VSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGV 1705

Query: 868  KDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPT 927
               +  G   P P       D   G S  G  N  + ++   W      GP  +  +   
Sbjct: 1706 AGGQVLGGARPGPA------DQSSGGSWAGTGNQSSGRS---WI-----GPGDQAVDCSK 1751

Query: 928  PMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGW-GNTPANAP--- 983
            P     A             G  +W        G G      AS   W G+ P N     
Sbjct: 1752 PEFEDQAC------------GGGSWA-------GAGSQ----ASGESWAGSRPGNEAIGG 1788

Query: 984  NAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASS 1032
            + M    ++    W  S+   +G    S+E E + G W   G++    S
Sbjct: 1789 SRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGS 1837



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 99/441 (22%), Positives = 140/441 (31%), Gaps = 76/441 (17%)

Query: 647  DKGTEGWESA-ATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNN 705
            +   + W  A A      G W  A  Q++      G+ S  T   D  + G W   +N  
Sbjct: 1252 ETSVKSWAGARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQA 1311

Query: 706  SSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA 765
            S        ++     W    + D  W GG+     W       GEE             
Sbjct: 1312 SGGSWALAGNQAIGELWAAGQASDGSWPGGQASGVSWV------GEEA------------ 1353

Query: 766  SKPVSGWGEGGQNEI--GTWGNGGNASLASKGGWE---DCKRSPAWNETGRQPNSWNKQH 820
               + G   G +N+   G+W   G  +++S   W    D     +W  T  Q    +K  
Sbjct: 1354 ---IGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGGSKPR 1410

Query: 821  QQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSP 880
             +          Q    GSW G      G         SSG   A   D+   G      
Sbjct: 1411 FED---------QASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGG------ 1455

Query: 881  QSISRKMDIDDGT-SAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTS-----KSA 934
               SR   +D  +  AW                 S GG  PR  N  T   S       A
Sbjct: 1456 ---SRLGHVDQSSGGAWAGTLD-----------QSGGGSKPRFENQTTEEGSWAGAGGQA 1501

Query: 935  SVWSKSTPPAPDNGTSAWGEPNESSPGW--GEMDD-TGASTTGWGNTPANAPNAMKPNSK 991
               SK  P    +G S     ++ S G+  G +D   G S TG G+  +  P  +  +  
Sbjct: 1502 GGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQV 1561

Query: 992  SMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGS-------ASSHNSASWGQGGKK 1044
            S +  W ++   V G       ++  G  W  TG Q S        S  N  SWG    +
Sbjct: 1562 SGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASGQ 1621

Query: 1045 QMKCSLKGGNND----SWMNP 1061
             +  S  G  N     SW +P
Sbjct: 1622 DVGGSRPGPTNQSSAGSWDSP 1642



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 176/812 (21%), Positives = 286/812 (35%), Gaps = 115/812 (14%)

Query: 122  AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGG--AAASNYANSTWGSGASSNNGT 179
            AG    T PGA   +   + A       TA D       A A   + S  GSG  +   T
Sbjct: 1126 AGSQGETLPGARDKSMSTSEA-----EATAEDEAYAKPEAEAMPTSESEGGSGTQACRKT 1180

Query: 180  SPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDN---NSASNPGSEKSTLPGSTT 236
             PN IH +     +G  +E+W  IA++        T D    NS S    E     GS +
Sbjct: 1181 QPN-IHDY---YWNGIGVEDW--IAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWS 1234

Query: 237  SNKGKGSQCQS-ASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGP 295
                K    +S A + +E ++  W           + +  EN  G+G W     Q   G 
Sbjct: 1235 GASDKAGIIRSWAVACDETSVKSW-----------AGARAENVVGIGTWARAGEQASGGL 1283

Query: 296  GSGFSNFN-----PNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350
             +G            ++  AW     + +    AL    + +  ++   GQ S       
Sbjct: 1284 WAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALA--GNQAIGELWAAGQASDGSWPGG 1341

Query: 351  ENAGVNFV---------VSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLG 401
            + +GV++V              QA   +  G   GN +S++  +    +  G   G   G
Sbjct: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGG---GSWAG 1398

Query: 402  NTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGAS 461
             + +S         D+ +G  GSW  A G +   ++ G  +  +          SW   +
Sbjct: 1399 TSDQSGGGSKPRFEDQASGE-GSWAGAGGQASGGSMLGPEDQSSG--------RSWADTA 1449

Query: 462  VQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELK 521
             Q S GS+    D   +S+GG+W  G  D            + G S+  ++  T  +   
Sbjct: 1450 DQASGGSRLGHVD---QSSGGAW-AGTLD-----------QSGGGSKPRFENQTTEE--- 1491

Query: 522  IGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEV-GGQSTGSNHKA 580
             G W+G        G          PE+Q +      GRS +++G ++ GG   G   +A
Sbjct: 1492 -GSWAG-------AGGQAGGGSKVGPEDQSS------GRSWANSGDQISGGFLVGIVDQA 1537

Query: 581  GSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVP 640
                   +G  +     P  +  +    S  D   +V+ ++  G         W      
Sbjct: 1538 NGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSW------ 1591

Query: 641  RPEGKSDKGTEGWESAATQTKNSGG-WGDAPSQS-NQMKSGWGELSASTEWKDPKNTGGW 698
               G  D+ + GW      ++ +GG WG A  Q     + G    S++  W  P +    
Sbjct: 1592 --AGTGDQAS-GWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSG 1648

Query: 699  NDYKNNNSSNWGGG--RP--DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754
            + +    + +  GG  +P  +++         + DQ  GG R  ++  SSG   WG    
Sbjct: 1649 SCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGG 1708

Query: 755  QTKNSNWESSASKPVSG-W-GEGGQNEIGTW-GNGGNASLASKGGWED-CKRSPAWNETG 810
            Q         A +   G W G G Q+   +W G G  A   SK  +ED      +W   G
Sbjct: 1709 QVLGGARPGPADQSSGGSWAGTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAG 1768

Query: 811  RQPN--SW--NKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866
             Q +  SW  ++   +     +         GSW        G  + S    ++      
Sbjct: 1769 SQASGESWAGSRPGNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFG 1828

Query: 867  PKDEEPSG---WEEPSPQSISRKMDIDDGTSA 895
            P  E   G   W E     +SR  D D+ T+A
Sbjct: 1829 PGAEAVIGSWCWTEEKADIVSRPDDKDEATTA 1860


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 139/608 (22%), Positives = 228/608 (37%), Gaps = 85/608 (13%)

Query: 225  GSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNW 284
            GS +S+  G   S  G+ S  Q +S  ++ +        +        S +  + G G +
Sbjct: 599  GSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQY 658

Query: 285  RNVSGQDR--------IGPGSGFSNFNPNSNPSAWPALVQEGT-SRKGALETDNSNSSAQ 335
             + SGQ           G  SGF      S  S++    Q G  S + +    + +SS Q
Sbjct: 659  GSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYG---QHGFGSSQSSGYGQHGSSSGQ 715

Query: 336  VSTVGQ--TSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTN------SLNLSSPN 387
             S  GQ   S  Q S     G     SG  Q+      G  +G ++      S +  S  
Sbjct: 716  TSGFGQHELSSGQSSSFGQHG-----SGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770

Query: 388  PMENKGMPFGMGLG-NTSRSTDAPSQ-STGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
               + G     G G + SR T    Q  +G  ++   G +G+  G S      G S SG 
Sbjct: 771  GQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHG-SGSGQ 829

Query: 446  NGNNGKEREDSWKGASVQKSTGSKNDS-WDNNNRSTGGSWNFGPQDSNDNKW-GEGNKMT 503
            +   G+    S + +  Q  +GS   S +  +  S+G +  FG   S+  ++ G G   +
Sbjct: 830  SSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGS 889

Query: 504  -SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSS 562
             SG S G  +  TGS     G++SG  Q  S +    +Q  +      G++Q+  +G+  
Sbjct: 890  GSGQSSGFGQHGTGS-----GQYSGFGQHESRS----HQSSYG-QHGSGSSQSSGYGQHG 939

Query: 563  SSTGSEVG--------GQSTG-SNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDL 613
            SS+G   G        GQS+G   H +GS  S   G+              ++  S+++ 
Sbjct: 940  SSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNY 999

Query: 614  DPR---VLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAP 670
                     ++G+GQ                  G S   T G+    + +    G+G   
Sbjct: 1000 GQHGSGSSQSSGYGQ-----------------HGSSSGQTTGFGQHRSSSGQYSGFGQHG 1042

Query: 671  SQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSN----WGGGRPDEKTPSSWNENP 726
            S S+Q  SG+G+    +       + G+  Y++ +  +     G G            N 
Sbjct: 1043 SGSDQ-SSGFGQHGTGS-----GQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNS 1096

Query: 727  SKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE----GGQNEIGT 782
             +  G+G  R P  G SSG   +G    Q+       S +   SG+ +     GQ+  G 
Sbjct: 1097 GQTSGFGQHR-PGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQ 1155

Query: 783  WGNGGNAS 790
             G G + S
Sbjct: 1156 HGTGSSQS 1163



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 199/949 (20%), Positives = 322/949 (33%), Gaps = 161/949 (16%)

Query: 121  GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
            G  P  C  P +NP +   +     +     P +  G     +  +S  G   S  + + 
Sbjct: 332  GGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSC 391

Query: 181  PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
             N  H +                  + + SSS N          GS +ST    +    G
Sbjct: 392  SNGQHEYGS--------------CGRFSNSSSSNEFSKCDQYGSGSSQST----SFEQHG 433

Query: 241  KGSQCQSASSGNECNLGVWKSDPKAKSVQS-----SNSTTENNNGLGNWRNVSGQDRIGP 295
             G    S    + C  G      ++ S QS       S++   +G G   + SGQ     
Sbjct: 434  TGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQS---- 489

Query: 296  GSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGV 355
             SGF      S  S+       G  + G++   +S      S  GQ+S   Q +  +   
Sbjct: 490  -SGFGQCGSGSGQSS-------GFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQS 541

Query: 356  NFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGM-GLGNTSRSTDAPSQST 414
            ++   G             +G++ S         E  G  FG  GLG+         QST
Sbjct: 542  SYGQHG-------------SGSSQSSGYGQYGSRETSG--FGQHGLGS--------GQST 578

Query: 415  GDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASV--QKSTGSKNDS 472
            G       G +G+    SG  +  GQ  SG+  ++G  + +S  G S   Q S+GS   S
Sbjct: 579  G------FGQYGSG---SGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSS 629

Query: 473  W--DNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530
                + +R T G    G   S    +G+     SG S G  +  +GS     G+ SG  Q
Sbjct: 630  GYGQHGSRQTSGFGQHGSGSSQSTGFGQYGS-GSGQSSGFGQHVSGS-----GQSSGFGQ 683

Query: 531  PNSSTGAWD-NQKGHPLPENQGNAQAPCWGRSSSSTGSEVG-GQSTGSNHKAGSSDSHNS 588
              S +G     Q G       G++Q+  +G+  SS+G   G GQ   S+ ++ S   H S
Sbjct: 684  HESRSGHSSYGQHGF------GSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGS 737

Query: 589  G--RRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKS 646
            G  + S    H                      ++G+GQ + +       +        S
Sbjct: 738  GSGQSSGFGQHGSGSG----------------QSSGFGQHESRSGQSSYGQHSSGSSQSS 781

Query: 647  DKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNS 706
              G  G    + QT   G  G   SQS    +G+G+  + +       + G+  + + + 
Sbjct: 782  GYGQHG----SRQTSGFGQHGSGSSQS----TGFGQYGSGSG-----QSAGFGQHGSGSG 828

Query: 707  SNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSAS 766
             + G G+ + ++  S     S  Q   G  Q     SSG    G    QT       S+S
Sbjct: 829  QSSGFGQHESRSHQS-----SYGQHGSGSSQ-----SSGYGQHGSSSGQTSGFGQHRSSS 878

Query: 767  KPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826
               SG+G+ G       G+G ++     G           +E+    +S+  QH      
Sbjct: 879  GQYSGFGQHGS------GSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYG-QHGSGSSQ 931

Query: 827  QQPPPPQPEASGSWGGPPPPPPGNVRPS---NSSWSSGPQPATPKDEEPSGWEEPSPQSI 883
                     +SG   G      G+ + S        SG      + E  SG      Q  
Sbjct: 932  SSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHE 991

Query: 884  SRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPP 943
            SR    + G    G   S  Y          Q G +          + ++       +  
Sbjct: 992  SRSSQSNYGQHGSGSSQSSGY---------GQHGSS----------SGQTTGFGQHRSSS 1032

Query: 944  APDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNA---MKPNSKSMQDGWGES 1000
               +G    G  ++ S G+G+       ++G+G   + +  +      +  S   G+G+ 
Sbjct: 1033 GQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQ- 1091

Query: 1001 DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 1049
             G  +G      +     G  +  G  GS S   S+ +GQ G    K S
Sbjct: 1092 HGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSG-QSSGFGQHGSGTGKSS 1139



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 225/1129 (19%), Positives = 383/1129 (33%), Gaps = 136/1129 (12%)

Query: 145  QSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIA 204
            + ES T  D        S Y +S+W  G    +G S             G       C  
Sbjct: 110  EEESETEEDEEDTPGHKSGYRHSSWSEG--EEHGYS------------SGHSRGTVKCRH 155

Query: 205  SKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
              ++         ++S +  GS+K     S+  +   G + +  SS  E    + KS   
Sbjct: 156  GSNSRRLGRQGNLSSSGNQEGSQKR-YHRSSCGHSWSGGKDRHGSSSVELRERINKSHIS 214

Query: 265  AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQE---GTSR 321
                + S    E+ +G  +W    G   +  G   S    NS  S     ++E   G+S 
Sbjct: 215  PS--RESGEEYESGSGSNSWER-KGHGGLSCGLETSGHESNSTQSR----IREQKLGSSC 267

Query: 322  KGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSL 381
             G+ ++   + +   S      R Q +        F   G + + I      ++G  + +
Sbjct: 268  SGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYI------QSGCQSGI 321

Query: 382  NLSSPNPMENKGMPFGMGLGNTSRSTDAPSQ-STGDRKTGSVGSWGAA-RGPSGTDTVSG 439
                 +   + G P G G   ++  + + SQ   G R+ G   + G   R  S   +  G
Sbjct: 322  KGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCG 381

Query: 440  QSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEG 499
            Q  SG + +    + +   G+  + S  S ++ +   ++   GS     Q ++  + G G
Sbjct: 382  QYGSGGSQSCSNGQHEY--GSCGRFSNSSSSNEFSKCDQYGSGS----SQSTSFEQHGTG 435

Query: 500  NKMTSGVSQGEWK--QPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPC 557
               +SG  Q      Q  G  E    +  G +Q  SS+G       H     Q +    C
Sbjct: 436  LSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQC 495

Query: 558  WGRSSSSTG----SEVGGQSTG-SNHKAGSSDSHNSGR---RSYRPTHPDCQAVLQTLLS 609
               S  S+G      V GQS+G   H + S  S   G+   RS + ++    +       
Sbjct: 496  GSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSG 555

Query: 610  RTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDA 669
                  R  S  G+GQ  +         +     G+S     G+    + +  S G+G  
Sbjct: 556  YGQYGSRETS--GFGQHGLGSGQSTGFGQYGSGSGQSS----GFGQHGSGSGQSSGFGQH 609

Query: 670  PSQSNQMKSGWGELSASTEWKD------PKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWN 723
             S+S Q  S +G+ S+ +           + T G+  + + +S + G G+    +  S  
Sbjct: 610  ESRSGQ--SSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSG 667

Query: 724  -----ENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE---- 774
                     +  G+G     +   S G++G+G    Q+       S+S   SG+G+    
Sbjct: 668  FGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGS--SQSSGYGQHGSSSGQTSGFGQHELS 725

Query: 775  -GGQNEIGTWGNG----------GNASLASKGGWEDCKRSP----AWNETGRQPNSWNKQ 819
             G  +  G  G+G          G+ S  S G  +   RS       + +G   +S   Q
Sbjct: 726  SGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQ 785

Query: 820  HQQQQP----PQQPPPPQPEASGSWGGPPPPPPG-NVRPSNSSWSSGPQPATPKDEEPSG 874
            H  +Q            Q    G +G       G     S S  SSG      +  + S 
Sbjct: 786  HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSY 845

Query: 875  WEEPSPQSIS----RKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMT 930
             +  S  S S    +       TS +G   S + +        S  G +       T   
Sbjct: 846  GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGT--G 903

Query: 931  SKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNA----M 986
            S   S + +    +  +     G  +  S G+G+   +   T G+G   + +  +     
Sbjct: 904  SGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQ 963

Query: 987  KPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQM 1046
              +      G+G+ +      +   + + E     +  G  GS SS  S+ +GQ G    
Sbjct: 964  HGSGSGQSSGFGQHES--GSGKSSGFGQHESRSSQSNYGQHGSGSS-QSSGYGQHGSSSG 1020

Query: 1047 KCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGD 1106
            + +  G +  S     + Q+S  G      D  S       GS     F         G 
Sbjct: 1021 QTTGFGQHRSS-----SGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGF---------GQ 1066

Query: 1107 FNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKL 1166
            +    R+   G         G++ S  Y +  +   S Q    G   P S  S       
Sbjct: 1067 YESRSRQSSYG-----QHGSGSSQSSGYGQHGS--NSGQTSGFGQHRPGSGQSSGFGQYG 1119

Query: 1167 SPSGSTLPNVSLGAIGTGLNPQNFAA----RQG-GSHGLFGNSTAQSRG 1210
            S SG    +   G  G+G    +  A    R G  S+G  G  ++QS G
Sbjct: 1120 SGSGQ---SSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSG 1165



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 188/972 (19%), Positives = 325/972 (33%), Gaps = 127/972 (13%)

Query: 121  GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWG---SGASSNN 177
            G+G    +  G + +++  T    Q  SG+   S  G   + +  +S +G   SG+  ++
Sbjct: 926  GSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSS 985

Query: 178  GTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTS 237
            G   +                       +   SS + T      S+ G         + S
Sbjct: 986  GFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGS 1045

Query: 238  NKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGS 297
            ++  G       SG     G ++S  +  S     S +  ++G G   + SGQ      S
Sbjct: 1046 DQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQT-----S 1100

Query: 298  GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNF 357
            GF    P S  S+       G  + G+    +S      S  G++S   Q +        
Sbjct: 1101 GFGQHRPGSGQSS-------GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYR------ 1147

Query: 358  VVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDR 417
              SG+     H T     G++ S               FG  +  +   + +    +   
Sbjct: 1148 --SGQSSYGQHGT-----GSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSG 1200

Query: 418  KTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNN 477
            ++   G +G+  G S T    G+S    +G+    R+++  G ++  +T   + S    +
Sbjct: 1201 QSTGFGQYGSGSGQS-TGLGQGESQQVESGSTVHGRQETTHGQTI--NTTRHSQSGQGQS 1257

Query: 478  RSTGGSWNFGPQDS-NDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTG 536
              TG       + S ++N   E +   S           GS   K G      Q     G
Sbjct: 1258 TQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQ-----G 1312

Query: 537  AWDNQKGHPLPE-NQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNS-GRRSYR 594
                Q+G      + G+ Q       S+ TGS   G+   S+  A  S+ H+    R + 
Sbjct: 1313 TTHGQRGDTTRHGHSGHGQ-------STQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHS 1365

Query: 595  PTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWE 654
                  QA  Q   S + +  R    T +GQT                 G    G     
Sbjct: 1366 QEQTHSQAGSQHGESESTVHER--HETTYGQT-------------GEATGHGHSGHGQST 1410

Query: 655  SAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRP 714
               ++T    G G + S  +++ SG      S E      T G    ++  S +   GR 
Sbjct: 1411 QRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQE-----QTHGQAGSQHGESGSTVHGR- 1464

Query: 715  DEKTPSSWNENPSKDQGWGGGRQPNQGWS-SGKNGWGEEVDQTKNSNWESSASKPVSGWG 773
               T      + ++   +  G+   +G S +G+ G G    ++ +S   S  S   SG  
Sbjct: 1465 -HGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGH--SESSDSEVHSGGSHTHSGHT 1521

Query: 774  EG------GQNEI-------GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQH 820
             G      G++E         T G  G+ +  S  G E   ++ +   TGRQ  S ++  
Sbjct: 1522 HGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGS-RTTGRQRTSHSEST 1580

Query: 821  QQQ--QPPQQPPPPQPEASGSWGGPPPPPP-----------GNVRPSNSSWSSGPQPATP 867
              +        P  +    G  G     P            G +  +     SG   +T 
Sbjct: 1581 DSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQ 1640

Query: 868  KDEEPSGWEEPSPQSISRKMDIDDGTS------AWGDPNSYNYKNVNLWDK-----NSQG 916
            +    +G  + S  S S   ++  G S        G   S + ++ ++  +     + Q 
Sbjct: 1641 RGSRTTG-RQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQT 1699

Query: 917  GPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWG 976
            G   R  +    +T+++ S     T     +G S + +    S G+     +G S T  G
Sbjct: 1700 GDTTRHAHYHHGLTTQTGS----RTTGRRGSGHSEYSD----SEGY-----SGVSHTHSG 1746

Query: 977  NTPANAPNAMKPNSKSMQDGWGE---SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033
            +T   A +    +   + +  G      G  T   H    +    G   TTG + S  S 
Sbjct: 1747 HTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGS-RTTGRRSSGHSE 1805

Query: 1034 NSASWGQGGKKQ 1045
             S S G  G  Q
Sbjct: 1806 YSDSEGHSGFSQ 1817



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 83/418 (19%), Positives = 148/418 (35%), Gaps = 65/418 (15%)

Query: 194  GSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASS--- 250
            GS   E   I  +   ++   T D +  S  G  +ST  GS+T+ + +    +S+ S   
Sbjct: 1830 GSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVH 1889

Query: 251  --GNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNP 308
              G+  + G   S  +++  +S ++  + +      +   GQ     G    + +P+   
Sbjct: 1890 SGGSHTHSGHTHSQARSQHGESESTVHKRH------QTTHGQT----GDTTEHGHPSHGQ 1939

Query: 309  SAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIH 368
            +     +Q G+   G   + +S  S      G +          AG ++  SG   + +H
Sbjct: 1940 T-----IQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESG---SSVH 1991

Query: 369  NTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG------SV 422
               G  +G T                    G     +ST   S++TG R +G      S 
Sbjct: 1992 ERHGTTHGQTADTTRH--------------GHSGHGQSTQRGSRTTGRRASGHSEYSDSE 2037

Query: 423  GSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRS--T 480
            G  G +   SG       S  G +G++  ER  +  G +   +  + +    +  R   T
Sbjct: 2038 GHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRT 2097

Query: 481  GGSWNFGPQDSNDNKWGEGNKMT-SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWD 539
             G    G  +S+D++   G   T SG + G+ +   G     I    G     +      
Sbjct: 2098 AGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRH 2157

Query: 540  NQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTH 597
             Q GH              G+S+     + G ++TG    + S  S +       PTH
Sbjct: 2158 GQSGH--------------GQST-----QTGSRTTGRQRSSHSESSDSEVHSEASPTH 2196



 Score = 35.0 bits (79), Expect = 0.67
 Identities = 88/456 (19%), Positives = 157/456 (34%), Gaps = 34/456 (7%)

Query: 158  GAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTD 217
            G+  S Y++S   SG S  +       H   +    GS   E      +   ++   T D
Sbjct: 1952 GSGHSEYSDSEGPSGVSHTHSG-----HTHGQA---GSHYPESGSSVHERHGTTHGQTAD 2003

Query: 218  NNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTEN 277
                 + G  +ST  GS T+  G+ +   S  S +E + GV  +       Q+ +   E+
Sbjct: 2004 TTRHGHSGHGQSTQRGSRTT--GRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGES 2061

Query: 278  NNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVS 337
             + +         +R G   G +        S      Q G+   G   + +S SS    
Sbjct: 2062 GSSV--------HERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEV 2113

Query: 338  TVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFG 397
              G +          A      SG   + IH   G  +G T     ++ +     G    
Sbjct: 2114 HSGVSHTHSGHTYGQARSQHGESG---SAIHGRQGTIHGQTGD---TTRHGQSGHGQSTQ 2167

Query: 398  MGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSW 457
             G   T R   + S+S+ D +  S  S     G + +   S    SG++G+  +      
Sbjct: 2168 TGSRTTGRQRSSHSESS-DSEVHSEAS-PTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQ 2225

Query: 458  KGASVQKSTGSKNDSWDNNNRSTG--GSWNFGPQDSNDNKWGEGNKM--TSGVSQGEWKQ 513
             G + + +      S    +R+TG  GS +    DS  + WG         G +  + +Q
Sbjct: 2226 TGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQ 2285

Query: 514  PTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQS 573
            P  +   ++    G     +  G      G+      G+  +      S S+  +  G S
Sbjct: 2286 PGSTVHGRLETTHGQTGDTTRHG----HSGYGQSTQTGSRSSRASHFQSHSSERQRHGSS 2341

Query: 574  TGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLS 609
                H +     ++ G   Y P+    +++  + LS
Sbjct: 2342 QVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLS 2377


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 162/770 (21%), Positives = 230/770 (29%), Gaps = 145/770 (18%)

Query: 807  NETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866
            N+  +Q     +Q QQQQ  Q P        G+ GG P P P             PQ   
Sbjct: 53   NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD---------MEQPQHGG 103

Query: 867  PKDEEPSGW-EEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQ---------- 915
             KD    G  + P P  +S+  D DD     G+P    Y++  L    +Q          
Sbjct: 104  AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGG 163

Query: 916  GGPA--PREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973
            GGPA  P   N        S     ++ P    +G        + SPG G M    A+  
Sbjct: 164  GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-------GQQSPGMGMMHSASAAAA 216

Query: 974  GWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033
            G       AP +M P   S +           G   P       GG     GS G     
Sbjct: 217  G-------APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269

Query: 1034 NSASWGQG------GKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV 1087
             + + G G             +  GG    +    A      G+LS         M   +
Sbjct: 270  GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA----GYGVLSSPRQQGGGMM---M 322

Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147
            G        + K A               GF+    ++   + + P   +L    S    
Sbjct: 323  GPGGGGAASLSKAAAG---------SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373

Query: 1148 CLGDEAP--CSPFSPSPSYKLSPSGSTLPNVSLG----AIGTGLNPQ----------NFA 1191
              G   P   SP +P P      S +     + G    A G GL              +A
Sbjct: 374  SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433

Query: 1192 ARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLS 1251
            A Q  SH      T       +   P++     R Q+     +P         +P     
Sbjct: 434  AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493

Query: 1252 PGLFNVGPQLSPQQIAMLSQLP------QIPQFQLACQLLLQQ-----QQQQQLLQNQRK 1300
            P     GPQ  P  I +  + P      Q PQ Q+  Q   Q      QQ QQ   +Q+ 
Sbjct: 494  P----PGPQRYP--IGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQP 547

Query: 1301 ISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLD-NMVPNALNVGL 1359
                +  Q +   ++     Q QQ   Q   G +  P    G   H D N++       L
Sbjct: 548  QPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSL 607

Query: 1360 PDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQ------- 1412
            PDL                    G +     GTE+      S      S   Q       
Sbjct: 608  PDLS-------------------GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP 648

Query: 1413 ---EANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGS 1469
                A+ H +     P  +  GSP               +GP   + +P    P    GS
Sbjct: 649  FSPHASPHLSSIPGGPSPSPVGSPVGSNQ--------SRSGPISPASIPGSQMPPQPPGS 700

Query: 1470 KSSNASWPPEFQPGVPWK----------------GIQNIDPESDPYVTPG 1503
            +S ++S P   Q  +P +                G Q   P   P+ +PG
Sbjct: 701  QSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 123/545 (22%), Positives = 187/545 (34%), Gaps = 92/545 (16%)

Query: 81   PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVT 140
            P  A+Y+P +   R++ QQD                  G G    P  APG  PN+  + 
Sbjct: 553  PPQAQYLPSQSQQRYQPQQD--------------MSQEGYGTRSQPPLAPG-KPNHEDLN 597

Query: 141  GALLQSE--------SGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192
              L+Q E        SG+  D   G  A  + A S  GS +S  + ++P           
Sbjct: 598  --LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 655

Query: 193  DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS--- 249
              S +   P  +   +   S     N S S P S  S +PGS    +  GSQ +S+S   
Sbjct: 656  HLSSIPGGPSPSPVGSPVGS-----NQSRSGPISPAS-IPGSQMPPQPPGSQSESSSHPA 709

Query: 250  -------------SGNECNLGVWKSDPKAKSVQSSNSTT---ENNNGLGNWRNVSGQDRI 293
                         +G + N  + +  P+      S   +   + + G+ +++  +     
Sbjct: 710  LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY 769

Query: 294  GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENA 353
            GP    S + P  N S  PA         G      S     +          Q   +  
Sbjct: 770  GP--QMSQYGPQGNYSRPPAY-------SGVPSASYSGPGPGMGISANNQMHGQGPSQPC 820

Query: 354  GVNFVVSGR-EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQ 412
            G   V  GR   A + N   P  GN +S+  SSP  M  +G P GMG          P  
Sbjct: 821  GA--VPLGRMPSAGMQNRPFP--GNMSSMTPSSPG-MSQQGGP-GMG----------PPM 864

Query: 413  STGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDS 472
             T +RK        A    +     +  S     G+     +     +S   S    N S
Sbjct: 865  PTVNRK--------AQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSS 916

Query: 473  WDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQP 531
               N ++    ++  P   N +    G  +   +S GE K P     LK  G+  G  QP
Sbjct: 917  SLMNTQAP--PYSMAPAMVNSSAASVG--LADMMSPGESKLPL---PLKADGKEEGTPQP 969

Query: 532  NSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRR 591
             S +    + +G   P   GN   P     SS++ S   G  + S    G   + +S + 
Sbjct: 970  ESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKS 1029

Query: 592  SYRPT 596
            S   T
Sbjct: 1030 SSSTT 1034



 Score = 38.5 bits (88), Expect = 0.061
 Identities = 151/744 (20%), Positives = 237/744 (31%), Gaps = 123/744 (16%)

Query: 708  NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767
            ++GG  P+  +PS+    PS+ Q          G      G G      K+   + +A+ 
Sbjct: 374  SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG----LGKDMGAQYAAAS 429

Query: 768  PVSGWGEGGQNEIGTWGNGGNASLASKGGWED--CKRSPAWNETGRQPNSWNKQHQQQQP 825
            P     +   +   + G  G     S+G   D    + P     G  P+S        QP
Sbjct: 430  PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS--------QP 481

Query: 826  PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISR 885
             Q  P P     GS+G     PPG  R     +  G Q  TP     +G + P  Q    
Sbjct: 482  QQSSPYP----GGSYG-----PPGPQR-----YPIGIQGRTP--GAMAGMQYPQQQM--- 522

Query: 886  KMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG---GPAPREPNLPTPMTSKSASVWSKSTP 942
                         P  Y  + V+ + +  Q       P+ P+LP P      S   +   
Sbjct: 523  -------------PPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQ 568

Query: 943  PAPDNGTSAWGEPNES--SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES 1000
            P  D     +G  ++   +PG    +D             N     +P+  S+ D  G  
Sbjct: 569  PQQDMSQEGYGTRSQPPLAPGKPNHED------------LNLIQQERPS--SLPDLSGSI 614

Query: 1001 DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWM- 1059
            D   TG            G   +T SQG  S+   + +       +  S+ GG + S + 
Sbjct: 615  DDLPTGTEATLSSAVSASG---STSSQGDQSNPAQSPFSPHASPHLS-SIPGGPSPSPVG 670

Query: 1060 NPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFR 1119
            +P+    S  G +S      S       GS S+           +      M   +   R
Sbjct: 671  SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQ---R 727

Query: 1120 PPNSKDMGTTDSGPYFEKLTLP------------FSNQDGCLGDEAPCSPFSPSPSYKLS 1167
             P     G   +GP       P             SN  G  G +   S + P  +Y   
Sbjct: 728  NPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRP 785

Query: 1168 PSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP--VQPLNSSPSLR 1225
            P+ S +P+ S    G G+             G+  N+    +G   P    PL   PS  
Sbjct: 786  PAYSGVPSASYSGPGPGM-------------GISANNQMHGQGPSQPCGAVPLGRMPSAG 832

Query: 1226 AQ---VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLAC 1282
             Q    P    S   S+  + Q    G+ P +  V  +      A++       Q +   
Sbjct: 833  MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR--- 889

Query: 1283 QLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVG 1342
            Q       Q  L+ +    SQ +            S +  Q       P M +S +  VG
Sbjct: 890  QGSFPGMNQSGLMASSSPYSQPMNNSS--------SLMNTQAPPYSMAPAMVNSSAASVG 941

Query: 1343 PKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSM 1402
                 D M P    + LP L+  G   G     S     Y   G  +  T       + M
Sbjct: 942  ---LADMMSPGESKLPLP-LKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPM 997

Query: 1403 MEGLPSVATQEANMHKNGAIVAPG 1426
                 S+++   +  ++ +I +PG
Sbjct: 998  SPSSASISSFHGD--ESDSISSPG 1019



 Score = 34.7 bits (78), Expect = 0.88
 Identities = 46/188 (24%), Positives = 70/188 (37%), Gaps = 38/188 (20%)

Query: 1313 LARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372
            L + ++  QQQQQQQQ+Q   +    HP+     L      A   G PD++   P  G  
Sbjct: 48   LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPG-PDMEQ--PQHGGA 104

Query: 1373 SGFSSGGM----------------DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANM 1416
               ++GG                 D     G+ AG   R++       GL ++ TQ+   
Sbjct: 105  KDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG--GRYEH-----PGLGALGTQQP-- 155

Query: 1417 HKNGAIVAPGKTRGGSPYNQFDIIPGDTL------GGHTGPAGDSWLPAKSPPTNKIGSK 1470
                 +  PG   G +   +F+   G         GG  GP  D     +SP    + S 
Sbjct: 156  ----PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211

Query: 1471 SSNASWPP 1478
            S+ A+  P
Sbjct: 212  SAAAAGAP 219


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
            sapiens]
          Length = 2178

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 162/770 (21%), Positives = 230/770 (29%), Gaps = 145/770 (18%)

Query: 807  NETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866
            N+  +Q     +Q QQQQ  Q P        G+ GG P P P             PQ   
Sbjct: 53   NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD---------MEQPQHGG 103

Query: 867  PKDEEPSGW-EEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQ---------- 915
             KD    G  + P P  +S+  D DD     G+P    Y++  L    +Q          
Sbjct: 104  AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGG 163

Query: 916  GGPA--PREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973
            GGPA  P   N        S     ++ P    +G        + SPG G M    A+  
Sbjct: 164  GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-------GQQSPGMGMMHSASAAAA 216

Query: 974  GWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033
            G       AP +M P   S +           G   P       GG     GS G     
Sbjct: 217  G-------APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269

Query: 1034 NSASWGQG------GKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV 1087
             + + G G             +  GG    +    A      G+LS         M   +
Sbjct: 270  GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA----GYGVLSSPRQQGGGMM---M 322

Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147
            G        + K A               GF+    ++   + + P   +L    S    
Sbjct: 323  GPGGGGAASLSKAAAG---------SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373

Query: 1148 CLGDEAP--CSPFSPSPSYKLSPSGSTLPNVSLG----AIGTGLNPQ----------NFA 1191
              G   P   SP +P P      S +     + G    A G GL              +A
Sbjct: 374  SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433

Query: 1192 ARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLS 1251
            A Q  SH      T       +   P++     R Q+     +P         +P     
Sbjct: 434  AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493

Query: 1252 PGLFNVGPQLSPQQIAMLSQLP------QIPQFQLACQLLLQQ-----QQQQQLLQNQRK 1300
            P     GPQ  P  I +  + P      Q PQ Q+  Q   Q      QQ QQ   +Q+ 
Sbjct: 494  P----PGPQRYP--IGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQP 547

Query: 1301 ISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLD-NMVPNALNVGL 1359
                +  Q +   ++     Q QQ   Q   G +  P    G   H D N++       L
Sbjct: 548  QPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSL 607

Query: 1360 PDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQ------- 1412
            PDL                    G +     GTE+      S      S   Q       
Sbjct: 608  PDLS-------------------GSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP 648

Query: 1413 ---EANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGS 1469
                A+ H +     P  +  GSP               +GP   + +P    P    GS
Sbjct: 649  FSPHASPHLSSIPGGPSPSPVGSPVGSNQ--------SRSGPISPASIPGSQMPPQPPGS 700

Query: 1470 KSSNASWPPEFQPGVPWK----------------GIQNIDPESDPYVTPG 1503
            +S ++S P   Q  +P +                G Q   P   P+ +PG
Sbjct: 701  QSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 153/723 (21%), Positives = 230/723 (31%), Gaps = 126/723 (17%)

Query: 708  NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767
            ++GG  P+  +PS+    PS+ Q          G      G G      K+   + +A+ 
Sbjct: 374  SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG----LGKDMGAQYAAAS 429

Query: 768  PVSGWGEGGQNEIGTWGNGGNASLASKGGWED--CKRSPAWNETGRQPNSWNKQHQQQQP 825
            P     +   +   + G  G     S+G   D    + P     G  P+S        QP
Sbjct: 430  PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS--------QP 481

Query: 826  PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISR 885
             Q  P P     GS+G     PPG  R     +  G Q  TP     +G + P  Q    
Sbjct: 482  QQSSPYP----GGSYG-----PPGPQR-----YPIGIQGRTP--GAMAGMQYPQQQM--- 522

Query: 886  KMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG---GPAPREPNLPTPMTSKSASVWSKSTP 942
                         P  Y  + V+ + +  Q       P+ P+LP P      S   +   
Sbjct: 523  -------------PPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQ 568

Query: 943  PAPDNGTSAWGEPNES--SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES 1000
            P  D     +G  ++   +PG    +D             N     +P+  S+ D  G  
Sbjct: 569  PQQDMSQEGYGTRSQPPLAPGKPNHED------------LNLIQQERPS--SLPDLSGSI 614

Query: 1001 DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWM- 1059
            D   TG            G   +T SQG  S+   + +       +  S+ GG + S + 
Sbjct: 615  DDLPTGTEATLSSAVSASG---STSSQGDQSNPAQSPFSPHASPHLS-SIPGGPSPSPVG 670

Query: 1060 NPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFR 1119
            +P+    S  G +S      S       GS S+           +      M   +   R
Sbjct: 671  SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQ---R 727

Query: 1120 PPNSKDMGTTDSGPYFEKLTLP------------FSNQDGCLGDEAPCSPFSPSPSYKLS 1167
             P     G   +GP       P             SN  G  G +   S + P  +Y   
Sbjct: 728  NPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRP 785

Query: 1168 PSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP--VQPLNSSPSLR 1225
            P+ S +P+ S    G G+             G+  N+    +G   P    PL   PS  
Sbjct: 786  PAYSGVPSASYSGPGPGM-------------GISANNQMHGQGPSQPCGAVPLGRMPSAG 832

Query: 1226 AQ---VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLAC 1282
             Q    P    S   S+  + Q    G+ P +  V  +      A++       Q +   
Sbjct: 833  MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR--- 889

Query: 1283 QLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVG 1342
            Q       Q  L+ +    SQ +            S +  Q       P M +S +  VG
Sbjct: 890  QGSFPGMNQSGLMASSSPYSQPMNNSS--------SLMNTQAPPYSMAPAMVNSSAASVG 941

Query: 1343 PKPHLDNMVPNALNVGLP---DLQTKG-PIPGYGSGFSSGGMDYGMVGGK--EAGTESRF 1396
                 D M P    + LP   D + +G P P   S  SS     G    K  E G E   
Sbjct: 942  ---LADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPER 998

Query: 1397 KQW 1399
            K W
Sbjct: 999  KLW 1001



 Score = 35.0 bits (79), Expect = 0.67
 Identities = 82/347 (23%), Positives = 123/347 (35%), Gaps = 66/347 (19%)

Query: 81  PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVT 140
           P  A+Y+P +   R++ QQD                  G G    P  APG  PN+  + 
Sbjct: 553 PPQAQYLPSQSQQRYQPQQD--------------MSQEGYGTRSQPPLAPG-KPNHEDLN 597

Query: 141 GALLQSE--------SGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192
             L+Q E        SG+  D   G  A  + A S  GS +S  + ++P           
Sbjct: 598 --LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 655

Query: 193 DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS--- 249
             S +   P  +   +   S     N S S P S  S +PGS    +  GSQ +S+S   
Sbjct: 656 HLSSIPGGPSPSPVGSPVGS-----NQSRSGPISPAS-IPGSQMPPQPPGSQSESSSHPA 709

Query: 250 -------------SGNECNLGVWKSDPKAKSVQSSNSTT---ENNNGLGNWRNVSGQDRI 293
                        +G + N  + +  P+      S   +   + + G+ +++  +     
Sbjct: 710 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY 769

Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENA 353
           GP    S + P  N S  PA         G      S     +          Q   +  
Sbjct: 770 GP--QMSQYGPQGNYSRPPAY-------SGVPSASYSGPGPGMGISANNQMHGQGPSQPC 820

Query: 354 GVNFVVSGR-EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMG 399
           G   V  GR   A + N   P  GN +S+  SSP  M  +G P GMG
Sbjct: 821 GA--VPLGRMPSAGMQNRPFP--GNMSSMTPSSPG-MSQQGGP-GMG 861



 Score = 34.7 bits (78), Expect = 0.88
 Identities = 46/188 (24%), Positives = 70/188 (37%), Gaps = 38/188 (20%)

Query: 1313 LARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372
            L + ++  QQQQQQQQ+Q   +    HP+     L      A   G PD++   P  G  
Sbjct: 48   LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPG-PDMEQ--PQHGGA 104

Query: 1373 SGFSSGGM----------------DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANM 1416
               ++GG                 D     G+ AG   R++       GL ++ TQ+   
Sbjct: 105  KDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG--GRYEH-----PGLGALGTQQP-- 155

Query: 1417 HKNGAIVAPGKTRGGSPYNQFDIIPGDTL------GGHTGPAGDSWLPAKSPPTNKIGSK 1470
                 +  PG   G +   +F+   G         GG  GP  D     +SP    + S 
Sbjct: 156  ----PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211

Query: 1471 SSNASWPP 1478
            S+ A+  P
Sbjct: 212  SAAAAGAP 219


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 105/439 (23%), Positives = 149/439 (33%), Gaps = 107/439 (24%)

Query: 619  SNTGWGQ-----TQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQS 673
            SN+GW         I  D+ W     P   G S     GW S       S  W   PS S
Sbjct: 32   SNSGWASPSASGASIPSDSGW---ASPSASGASTPSNSGWASF------SASWASIPSDS 82

Query: 674  NQMKSGWGELSASTEWKDPKNTGGWNDYKNNNS---SNWGGGRPD---EKTPSSWNENPS 727
                 GW   SAS  W    +  GW     + +   S+ G   P       PS++  +PS
Sbjct: 83   -----GWASPSAS--WASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFWASPS 135

Query: 728  KDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGG 787
                 G     + GW+S    W      + +S W S    P + W     +   +  +G 
Sbjct: 136  AS---GASTPSDSGWASPSASW---ASTSSDSGWAS----PSASWTSPSASCASSSASG- 184

Query: 788  NASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP 847
             AS  S  GW     S  W                              S SW   P   
Sbjct: 185  -ASTPSDSGW--ASPSVFW---------------------------VSPSTSWASSPSDF 214

Query: 848  PGNVRPSNSSWSS------GPQPATPKDEEPSGWEEPSPQ--SISRKMDIDDGTSAWGDP 899
                 PS+S W+S       P  +       SGW  PS    S S         S W   
Sbjct: 215  GWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWAS- 273

Query: 900  NSYNYKNVN----------LWDKNSQG-GPAPREPNLPTPMTSKSASV-------WSKST 941
            +S ++ ++            W  +S     AP +    +P  S+++++       +S S 
Sbjct: 274  SSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASG 333

Query: 942  PPAP-DNG---TSAWGEPNESSPGWGEMDDTGAST---TGWGNTPAN--APNAMKPNSKS 992
              AP D+G    SA G    S  GW     +GAST   +GW +  A+  +P+A   ++ S
Sbjct: 334  ASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPS 393

Query: 993  MQDGWGESDGPVTGARHPS 1011
               GW       +GA  PS
Sbjct: 394  -DSGWASPS--ASGASMPS 409



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 90/411 (21%), Positives = 136/411 (33%), Gaps = 56/411 (13%)

Query: 431 PSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTG-----------SKNDSWDNNNRS 479
           PSG+   S  ++  +  +N      S  GAS+   +G             N  W     S
Sbjct: 15  PSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGW----AS 70

Query: 480 TGGSWNFGPQDSNDNKWGEGN-KMTSGVSQGEWKQP--TGSDELKIGEWSGPNQPNSS-- 534
              SW   P DS    W   +    S  S   W  P  +G+       W+ P+   +S  
Sbjct: 71  FSASWASIPSDSG---WASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIP 127

Query: 535 TGAW--DNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRS 592
           +  W   +  G   P + G A       S+SS        ++ ++  A  + S  SG  +
Sbjct: 128 SAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGAST 187

Query: 593 YRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEV----PRPEGKSDK 648
             P+     +     +S +       S+ GW  T    D+ W         P   G S  
Sbjct: 188 --PSDSGWASPSVFWVSPSTSWASSPSDFGWAST--PSDSGWASSSASCISPSASGASTS 243

Query: 649 GTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGW---NDYKNNN 705
              GW S       S  W    +      S  G  S+S  W    +  GW   +    ++
Sbjct: 244 SDSGWASP------SASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASS 297

Query: 706 SSNWGGGRPD--EKTPSSWNENPSKDQGW------GGGRQPNQGWSSGKNGWGEEVDQTK 757
           S++W     D    +PS    +     GW      G     + GW+S        V  T 
Sbjct: 298 SASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHS---ASGVSTTS 354

Query: 758 NSNWES-SASKPVSGWGEGGQNEIGTWG--NGGNASLASKGGWEDCKRSPA 805
           +S W S SAS   +    G  +   +W   +   AS  S  GW     S A
Sbjct: 355 DSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGA 405



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 62/247 (25%), Positives = 94/247 (38%), Gaps = 41/247 (16%)

Query: 834  PEASGSW-----GGPPPPPPGNVRPSNSSWSS--GPQPATPKDEEPSGWEEPSPQSISRK 886
            P ASG+      G   P   G   PSNS W+S      + P D   SGW  PS    S  
Sbjct: 39   PSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPSD---SGWASPSASWASTP 95

Query: 887  MDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPD 946
             D     S W  P++      ++   +    P+    ++P+   + S S    STP    
Sbjct: 96   SD-----SGWASPSA---SGASIPSDSGWASPSVSGASIPSAFWA-SPSASGASTP---- 142

Query: 947  NGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPAN--APNAMKPNSKSMQDGWGESDGPV 1004
               S W  P+ S   W     + +S +GW +  A+  +P+A   +S +     G S    
Sbjct: 143  -SDSGWASPSAS---WA----STSSDSGWASPSASWTSPSASCASSSAS----GASTPSD 190

Query: 1005 TGARHPSWEEEEDGGVWNTTGSQ-GSASSHNSASWGQGGKKQMKCSLKGGNNDS---WMN 1060
            +G   PS         W ++ S  G AS+ + + W       +  S  G +  S   W +
Sbjct: 191  SGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWAS 250

Query: 1061 PLAKQFS 1067
            P A   S
Sbjct: 251  PSASWVS 257



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 94/469 (20%), Positives = 172/469 (36%), Gaps = 71/469 (15%)

Query: 121 GAGPPPCTAPGAN-PNNA-----QVTGALLQSESGTAPDSTLGGAAASNYA----NSTWG 170
           G+G    +A GA+ P+N+       +GA + S+SG A  S  G +  SN      +++W 
Sbjct: 17  GSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWA 76

Query: 171 SGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKST 230
           S  S +   SP+    W     D      W    +  + S +   +D+  AS P    ++
Sbjct: 77  SIPSDSGWASPSA--SWASTPSDSG----W----ASPSASGASIPSDSGWAS-PSVSGAS 125

Query: 231 LPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQ 290
           +P +  ++         + SG       W S   + +  SS+S   + +   +W + S  
Sbjct: 126 IPSAFWASPSASGASTPSDSG-------WASPSASWASTSSDSGWASPS--ASWTSPSAS 176

Query: 291 DRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350
                 SG S   P+ +  A P++     S   A         +  S  G  S    S  
Sbjct: 177 CASSSASGAS--TPSDSGWASPSVFWVSPSTSWA---------SSPSDFGWASTPSDSGW 225

Query: 351 ENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAP 410
            ++  + +      A   +  G  + + + ++ S+     +       G  ++S S D+ 
Sbjct: 226 ASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSS----DSGWASSSASWDSI 281

Query: 411 SQSTG-----DRKTGSVGSWGAARGPSGTD--TVSGQSNSGNNGNNGKEREDSWKGASVQ 463
           +  +G          S  SW +A   SG+   +VS  S    +G         W   S  
Sbjct: 282 TSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSG---------WASFSAS 332

Query: 464 KSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKM-TSGVSQGEWKQPTGSDELKI 522
            ++   +  W +++ S       G   ++D+ W   +    S  S   W  P+ S     
Sbjct: 333 GASAPSDSGWTSHSAS-------GVSTTSDSGWASPSASGASTSSDSGWASPSAS--WAS 383

Query: 523 GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGG 571
              SG + P+ S  A  +  G  +P         C+ + ++ TG  V G
Sbjct: 384 PSASGASTPSDSGWASPSASGASMPSAPSLCPGSCFPQLTARTGFTVVG 432



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 65/303 (21%), Positives = 98/303 (32%), Gaps = 43/303 (14%)

Query: 436 TVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNK 495
           + SG S   ++G        SW   S      S + SW + + S   S   G    +D+ 
Sbjct: 135 SASGASTPSDSG--WASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSG 192

Query: 496 WGE--------GNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
           W               S  S   W   T SD       +    P++S  +  +  G   P
Sbjct: 193 WASPSVFWVSPSTSWASSPSDFGWAS-TPSDSGWASSSASCISPSASGASTSSDSGWASP 251

Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSH--------NSGRRSYRPTHPD 599
               +A       S +ST S+ G  S+ ++  + +SDS          S   S+     D
Sbjct: 252 ----SASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSD 307

Query: 600 CQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQ 659
             +   ++ SR       LS +GW        +             SD G     ++   
Sbjct: 308 SGSSSPSV-SRAS----TLSVSGWASFSASGASA-----------PSDSGWTSHSASGVS 351

Query: 660 TKNSGGWGD--APSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEK 717
           T +  GW    A   S    SGW   SAS  W  P  +G      +  +S    G     
Sbjct: 352 TTSDSGWASPSASGASTSSDSGWASPSAS--WASPSASGASTPSDSGWASPSASGASMPS 409

Query: 718 TPS 720
            PS
Sbjct: 410 APS 412


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 70/343 (20%), Positives = 128/343 (37%), Gaps = 15/343 (4%)

Query: 146 SESGTAPDSTLGGAAASNYANSTWGSGAS--SNNGTSPNPIHIWDKVIVDGSDMEEWPCI 203
           SES T   ++ G + A+N  +ST  SGAS  +N+ +S            D S        
Sbjct: 108 SESST---TSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164

Query: 204 AS---KDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWK 260
           A+     T SS  +T  N+ +S   S  ST   S +S    G+   + S     + G   
Sbjct: 165 ATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGT 224

Query: 261 SDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTS 320
           +     S  SS ++T  N       + S     G G+  ++ +  ++  A  A   E ++
Sbjct: 225 ATNSESSTTSSGASTATN-------SESSTPSSGAGTATNSESSTTSSGAGTATNSESST 277

Query: 321 RKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNS 380
               + T  ++ S+  S+   T+   +S   ++G N   +              N  +++
Sbjct: 278 VSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESST 337

Query: 381 LNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQ 440
            +  +     ++      G    + S  + + S     T S  S  ++   + T + S  
Sbjct: 338 TSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESST 397

Query: 441 SNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGS 483
           ++SG +     E      GAS   ++ S   S   N  +  GS
Sbjct: 398 TSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGS 440



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 83/471 (17%), Positives = 167/471 (35%), Gaps = 25/471 (5%)

Query: 141 GALLQSESGTAPDSTLGGAAASNYANSTWGSGASS--NNGTSPNPIHIWDKVIVDGSDME 198
           G LL  E+ T  + T   + ++N  +S   SGAS+  N+G+S     +    I   S   
Sbjct: 13  GLLLHLEAATNSNET---STSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTS 69

Query: 199 EWPCIASKD---TESSSENTTDNNSASN--------PGSEKSTLPGSTTSNKGKGSQCQS 247
               I +     T SS  +T  N+  S           SE ST     ++     S   S
Sbjct: 70  NGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPS 129

Query: 248 ASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSN 307
           + +    N     +   A +  +S+S+T ++       + S     G  +  ++ +   +
Sbjct: 130 SGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVS 189

Query: 308 PSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQI 367
             A  A   E ++      T  ++ S   S    T+   +S   ++G +   +       
Sbjct: 190 SRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPS 249

Query: 368 HNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGA 427
                  N  +++ +  +     ++      G+   + S  +   S  +  T S  S  +
Sbjct: 250 SGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTS 309

Query: 428 ARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFG 487
           +   + T++ S  ++SG +     E   +  GAS   ++ S   S   +  +  GS    
Sbjct: 310 SGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTS 369

Query: 488 PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
              S      E + ++SG S     +   S     G  +  N  +S+  +     G    
Sbjct: 370 SGTSTATN-SESSTVSSGASTATTSE---SSTTSSGASTATNSESSTVSS-----GASTA 420

Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHP 598
            N  ++       +++++GS V    +G+    G   + +S   +     P
Sbjct: 421 TNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471



 Score = 38.5 bits (88), Expect = 0.061
 Identities = 34/141 (24%), Positives = 57/141 (40%), Gaps = 11/141 (7%)

Query: 140 TGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEE 199
           +GA   + S ++  S+ G + A+N  +ST  SGAS+   +  +            S    
Sbjct: 310 SGANTATNSDSSTTSS-GASTATNSESSTTSSGASTATNSESSTT----------SSGAS 358

Query: 200 WPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVW 259
               +   T SS  +T  N+ +S   S  ST   S +S    G+   + S  +  + G  
Sbjct: 359 TATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGAS 418

Query: 260 KSDPKAKSVQSSNSTTENNNG 280
            +     S  SS + T  N+G
Sbjct: 419 TATNSESSTTSSGANTATNSG 439



 Score = 35.8 bits (81), Expect = 0.39
 Identities = 73/372 (19%), Positives = 127/372 (34%), Gaps = 59/372 (15%)

Query: 671  SQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGG-----RPDEKTPSSWNEN 725
            S+S+   SG    S +T  +    + G +   N++SS    G       D  T SS    
Sbjct: 108  SESSTTSSG---ASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164

Query: 726  PSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGN 785
             +  +        + G S+  N     V    ++   S +S   SG      +E  T  N
Sbjct: 165  ATNSES----STTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSN 220

Query: 786  GGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845
            G   +  S+        S A N     P+S                     +G+      
Sbjct: 221  GAGTATNSESSTTSSGASTATNSESSTPSS--------------------GAGT------ 254

Query: 846  PPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYK 905
                     +S+ SSG   AT  +             IS   + +  T + G   + N +
Sbjct: 255  ----ATNSESSTTSSGAGTATNSESSTVS------SGISTVTNSESSTPSSGANTATNSE 304

Query: 906  NVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEM 965
            +       S G       +  T  +  S +  S+S+  +    T+   E + +S G    
Sbjct: 305  S----STTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTA 360

Query: 966  DDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTG 1025
             ++G+STT  G + A    +   +S +      ES    +GA   +  E       ++T 
Sbjct: 361  TNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSE-------SSTV 413

Query: 1026 SQGSASSHNSAS 1037
            S G++++ NS S
Sbjct: 414  SSGASTATNSES 425


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 55/137 (40%), Positives = 73/137 (53%), Gaps = 22/137 (16%)

Query: 1207 QSRGLHTPV-----QPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQL 1261
            Q+ GL +P      +PL    S+ A + PQ I+PQ    +L+Q     LSP        L
Sbjct: 69   QTSGLKSPKSSDKQRPLQVPVSV-AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---L 121

Query: 1262 SPQQIAMLSQLPQIPQF------QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLAR 1315
              QQ A++ Q  Q+ +F      QL  QLL QQQQQQQ  Q Q++  Q  +QQQ+QQ  +
Sbjct: 122  LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 181

Query: 1316 MVSALQQQQQQQQRQPG 1332
                 QQQQQQQQ+ PG
Sbjct: 182  Q----QQQQQQQQQHPG 194



 Score = 31.2 bits (69), Expect = 9.7
 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319
            Q   QQ     Q  Q P  Q A +   QQQQQQQL   Q    Q + Q Q+ Q  + + +
Sbjct: 177  QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 235

Query: 1320 LQQQ 1323
            LQ+Q
Sbjct: 236  LQRQ 239


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 199/963 (20%), Positives = 333/963 (34%), Gaps = 189/963 (19%)

Query: 152  PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211
            P S+ GG   S +  S   SG S  + +   P     +   D S  +  P  AS+ T + 
Sbjct: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTP-----QGRSDASHGQSGPRSASRQTRNE 1547

Query: 212  SENTTDNNSASNPGSEKSTLPGSTT-SNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
             ++   +  + +   E ST  GS+  S  G+G    S +S  + +      D +  S  S
Sbjct: 1548 EQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDS 1607

Query: 271  ---SNSTTENNNGLGNWRNVSG--------QDRIGPG--------SGFSNFNPNSNPSAW 311
               S S + N+ G    ++  G        +DR   G        SG  +   +S   A 
Sbjct: 1608 ERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQA- 1666

Query: 312  PALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTD 371
             +  ++  S  G         SA  ST   T R Q S +     N   SG   +Q  +++
Sbjct: 1667 ASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSG---SQASDSE 1723

Query: 372  G-PKNGNTNSLNL---SSPNPMENKGMPFGMGLGNTSRS--------TDAPSQSTGDRKT 419
            G  +  +T S++    + P+   ++    G     + RS        T   S+S   R  
Sbjct: 1724 GHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTG 1783

Query: 420  GSVGSWGAAR------------GPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTG 467
             S G    +R               G DT+ G   S   G  G   E S   +    S  
Sbjct: 1784 PSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHH 1843

Query: 468  SKNDSWDNNNRSTG--GSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEW 525
            S   S + ++ S G  GS +   Q  N+ + G+G++ +         +   S   ++G+ 
Sbjct: 1844 SHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQG 1903

Query: 526  --SGP----NQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNH- 578
              SGP    NQ +S +   D+Q GH     + +  A      S+   S  G +  GS+H 
Sbjct: 1904 QSSGPRTSRNQGSSVSQDSDSQ-GHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHE 1962

Query: 579  -KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIE 637
             +AG   S +S R+S                       R   ++  GQ     +      
Sbjct: 1963 DRAGHGHSADSSRQS---------------------GTRHTESSSRGQAASSHE------ 1995

Query: 638  EVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGG 697
                 + +S  G           +  G      S  +   SG G   AS+  +D  + G 
Sbjct: 1996 -----QARSSAG-----------ERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRG- 2038

Query: 698  WNDYKNNNSSNWGGGRPDEKTPSSWNENPS--KDQGWGGGRQPNQGWSSGKNG-WGEEVD 754
               Y  + +S+  G   D  T S   +  +    Q      +   G SSG++G +  +V 
Sbjct: 2039 ---YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095

Query: 755  QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPN 814
              + S      S P +G  +G   +        +   AS+ G +  +  P  +  GRQ +
Sbjct: 2096 THEQSESTHGQSAPSTGGRQGSHYD---QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152

Query: 815  SWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPK--DEEP 872
                 HQ+Q           + SG  G          R   S   SG + A+ K  D+E 
Sbjct: 2153 -----HQEQSV---------DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQ 2198

Query: 873  SGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSK 932
            SG  + S  S S   +     S+W D + ++     L  +    GP    P         
Sbjct: 2199 SG--DGSRHSGSHHHE----ASSWADSSRHS-----LVGQGQSSGPRTSRPR-------- 2239

Query: 933  SASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKS 992
                           G+S     ++ S   G  +D+   +   G+   N   + +  S+ 
Sbjct: 2240 ---------------GSSV----SQDSDSEGHSEDSERRS---GSASRNHHGSAQEQSRD 2277

Query: 993  MQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN--SASWGQGGKKQMKCSL 1050
                         G+RHP    E+  G  ++  S   + +H+  ++S GQ      +   
Sbjct: 2278 -------------GSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARS 2324

Query: 1051 KGG 1053
              G
Sbjct: 2325 SAG 2327



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 112/614 (18%), Positives = 225/614 (36%), Gaps = 92/614 (14%)

Query: 210  SSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQ 269
            S  E + D +  S      +T  G + +++G+ S  +SAS          K+  K +S  
Sbjct: 2152 SHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ-SGSRSASR---------KTYDKEQSGD 2201

Query: 270  SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
             S  +  +++   +W + S    +G G    +  P ++     ++ Q+  S   + +++ 
Sbjct: 2202 GSRHSGSHHHEASSWADSSRHSLVGQGQ---SSGPRTSRPRGSSVSQDSDSEGHSEDSER 2258

Query: 330  SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
             + SA  +  G  S ++QS+           G    + H+ D   +G++   +  S    
Sbjct: 2259 RSGSASRNHHG--SAQEQSR----------DGSRHPRSHHEDRAGHGHSAESSRQS---- 2302

Query: 390  ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNN 449
                     G  +   S+   + S+ ++   S G    +      D+ S  S  G+   +
Sbjct: 2303 ---------GTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS-SRHSGIGHGQAS 2352

Query: 450  GKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGP------QDSNDNKWGEGNKMT 503
               R+   +G+S  +++ S+  S D++ +S       GP      + +     G   +  
Sbjct: 2353 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 2412

Query: 504  SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQK------------GHPLPENQG 551
            S + Q    + + S   + G  +G  Q +    A D+ +            GHP   + G
Sbjct: 2413 SFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGG 2472

Query: 552  -------------------NAQAPCWGRSSSS---TGSEVGGQSTGSNHKAGSSDSHNSG 589
                               ++     GRS +S   +GS    + T ++ ++G    H+  
Sbjct: 2473 RQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGS 2532

Query: 590  RRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKG 649
            R     +  D     Q    +++  PR   N G   +Q   D+    E+  R  G + + 
Sbjct: 2533 RHHEASSRADSSGHSQVGQGQSE-GPRTSRNWGSSFSQ-DSDSQGHSEDSERWSGSASRN 2590

Query: 650  TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNT----GGWNDYKNNN 705
              G  SA  Q ++       P    + ++G G  + S+     ++T    GG     +  
Sbjct: 2591 HHG--SAQEQLRDG---SRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQ 2645

Query: 706  SSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA 765
            + +  G R       S   + S+  G G G+  +    SG  G+          + E S 
Sbjct: 2646 ARSSAGERHGSHHQQS--ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 2703

Query: 766  SKPVSGWGEGGQNE 779
            ++ VS  G+ G ++
Sbjct: 2704 TQSVSAHGQAGSHQ 2717



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 130/679 (19%), Positives = 238/679 (35%), Gaps = 85/679 (12%)

Query: 120  GGAGPPPCTAPGANPNNAQVTGALLQSESGTA-----PDSTLGGAAASNYANSTWGSGAS 174
            G  GP      G+    AQ +     S+ G       P S+ GG    ++ +S   SG S
Sbjct: 2753 GWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS 2812

Query: 175  SNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGS 234
             ++ +     H   +   D S  +     AS+ T +  ++   +  + +   E ST    
Sbjct: 2813 GSHHS-----HTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867

Query: 235  TTSNKGKGSQCQSASSGNECNLGVWK-SDPKAKSVQS---SNSTTENNNGLGNWRNVSGQ 290
            +  ++    Q + +         V + SD +  S  S   S S + N++G       S Q
Sbjct: 2868 SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHG-------SAQ 2920

Query: 291  DRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350
            +++  GS     +P S+        + G          +     Q S+ GQ +   +   
Sbjct: 2921 EQLRDGSR----HPRSHQED-----RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2971

Query: 351  ENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAP 410
             +AG       ++ A      G  +G  +S    S +    +G        N   S D+ 
Sbjct: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH----RGYSGSQASDNEGHSEDSD 3027

Query: 411  SQSTGDRKTGSVGSWG-----AARGPSGTDTVSGQSNSGNNGNNGKEREDS---WKGASV 462
            +QS      G  GS       +ARG SG    SG S S     +  E+ +S   W G S 
Sbjct: 3028 TQSVSAH--GQAGSHQQSHQESARGRSGE--TSGHSGSFLYQVSTHEQSESSHGWTGPST 3083

Query: 463  QKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKI 522
            +   GS+++   +++R +   +    QD+     G                         
Sbjct: 3084 RGRQGSRHEQAQDSSRHSASQYG---QDTIRGHPGSSR---------------------- 3118

Query: 523  GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGS 582
            G   G +  +S   +  +   H    +QG + A     S   +GS    ++T +  ++G 
Sbjct: 3119 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA-----SRGQSGSRSASRTTRNEEQSGD 3173

Query: 583  SDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRP 642
            S  H+  R     TH D     Q +  +++   R  S           D+    E+  R 
Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRR--SRRQGSSVSQDSDSEGHSEDSERW 3231

Query: 643  EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYK 702
             G + +   G  S   Q+++       P   ++ ++G G  +  +     ++    +  +
Sbjct: 3232 SGSASRNHRG--SVQEQSRHG---SRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQ 3286

Query: 703  NNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNS--N 760
              +S       P E+  S   ++    +  G  R            WG    Q  +S  +
Sbjct: 3287 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH 3346

Query: 761  WESSASKPVSGWGEGGQNE 779
             E S ++ VSG G+ G ++
Sbjct: 3347 SEESDTQSVSGHGQAGPHQ 3365



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 156/780 (20%), Positives = 261/780 (33%), Gaps = 110/780 (14%)

Query: 152  PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211
            P S+ GG   S+Y      SG S ++ +     H   +   D S        AS+ T + 
Sbjct: 2466 PGSSSGGRQGSHYEQLVDRSGHSGSHHS-----HTTSQGRSDASHGHSGSRSASRQTRND 2520

Query: 212  SENTTDN-NSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
             ++   + +S S      S    S  S  G+G      +S N  +     SD +  S  S
Sbjct: 2521 EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS 2580

Query: 271  ---SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
               S S + N++G       S Q+++  GS     +P S+        + G         
Sbjct: 2581 ERWSGSASRNHHG-------SAQEQLRDGSR----HPRSHQED-----RAGHGHSADSSR 2624

Query: 328  DNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPN 387
             +     Q S+ GQ +   +    +AG       ++ A      G  +G  +S    S +
Sbjct: 2625 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH 2684

Query: 388  PMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWG-----AARGPSG--------- 433
                +G        N   S D+ +QS      G  GS       +ARG SG         
Sbjct: 2685 ----RGYSGSQASDNEGHSEDSDTQSVSAH--GQAGSHQQSHQESARGRSGETSGHSGSF 2738

Query: 434  ---------TDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSW 484
                     +++  G +     G  G   E +   +    S   ++    +   S GG  
Sbjct: 2739 LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQ 2798

Query: 485  NFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH 544
             +  + S D+    G+  +   SQG      G    +    +  N+  S  G+  +   H
Sbjct: 2799 GYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRH 2858

Query: 545  PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604
                ++ +  A     S +  G   G + +     + S DS + G       H +     
Sbjct: 2859 ----HEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEG-------HSEDSERW 2907

Query: 605  QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664
                SR        ++ G  Q Q++  +           G         +S    T+ S 
Sbjct: 2908 SGSASR--------NHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSS 2959

Query: 665  GWGDAPSQSNQMKSGWGELSAS--TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSW 722
            G G A S   Q +S  GE   S   +  D     G    + +++    G R    + +S 
Sbjct: 2960 G-GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 3018

Query: 723  NENPSKD--------QGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA---SKPVSG 771
            NE  S+D         G  G  Q +    S +   GE    + +  ++ S    S+   G
Sbjct: 3019 NEGHSEDSDTQSVSAHGQAGSHQQSH-QESARGRSGETSGHSGSFLYQVSTHEQSESSHG 3077

Query: 772  W----GEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQ 827
            W      G Q          +   AS+ G +  +  P  +  GRQ   ++ +H       
Sbjct: 3078 WTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQ--GYHHEH------- 3128

Query: 828  QPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPA--TPKDEEPSGWEEPSPQSISR 885
                   ++SG  G          R   S   SG + A  T ++EE SG  + S  S+SR
Sbjct: 3129 -----SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSG--DSSRHSVSR 3181



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 189/945 (20%), Positives = 323/945 (34%), Gaps = 121/945 (12%)

Query: 152  PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211
            P S  GG   S++  S   SG S ++ +     H   +   D S  +     AS+ T   
Sbjct: 1169 PGSRRGGRQGSHHEQSVDRSGHSGSHHS-----HTTSQGRSDASHGQSGSRSASRQTRKD 1223

Query: 212  SENTTDN-NSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
             ++   + +S S      S    S  S  G+     S +S ++ +     SD +  S  S
Sbjct: 1224 KQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDS 1283

Query: 271  ---SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
               S S + N++G       S +++   GS    F+     S   +   + + + G   T
Sbjct: 1284 ERLSGSASRNHHG-------SSREQSRDGSRHPGFHQEDRASHGHSA--DSSRQSGTHHT 1334

Query: 328  DNSNSSAQVSTVGQT---------SREQQS--KMENAGVNFVVSGREQAQIHNTDGPKNG 376
            ++S+    VS+  Q          SR QQS     ++G+     G  QA     D    G
Sbjct: 1335 ESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI-----GHRQASSAVRDSGHRG 1389

Query: 377  N-----TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGP 431
            +     TNS   S  +  ++       G    S    A  QS G+    S          
Sbjct: 1390 SSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQS-GESSGRSRSFLYQVSSH 1448

Query: 432  SGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDS 491
              +++  GQ+     G  G   E +   +    S   ++    +   S GG      + S
Sbjct: 1449 EQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQS 1508

Query: 492  NDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQG 551
             D     G   +    QG      G    +       N+  S  G+  +   H  P    
Sbjct: 1509 VDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPST-- 1566

Query: 552  NAQAPCWGRSSSSTGSEVG-GQSTGS--NHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLL 608
                    R+ SS  S+VG G+S GS  + + GSS S +           D +   +   
Sbjct: 1567 --------RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDR----------DSEGHSEDSE 1608

Query: 609  SRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGD 668
             R++   R    +   Q++         +E     G S    E    + T+   +   G 
Sbjct: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHS---AESSRQSGTRHAETSSGGQ 1665

Query: 669  APSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWG--GGRPDEKTPSSWNENP 726
            A S   Q +S  GE   S   +   ++      +  +SS  G  G R    + +S +E  
Sbjct: 1666 AASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH 1725

Query: 727  SKD--------QGWGGGRQPN-----QGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWG 773
            S++         G  G  Q +     +G S  ++G         +++ +S ++   +G  
Sbjct: 1726 SEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPS 1785

Query: 774  EGG-QNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPP 832
             GG Q          +   AS+ G +  +  P  +  GRQ +     H +Q         
Sbjct: 1786 TGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGS-----HYEQ--------- 1831

Query: 833  QPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT--PKDEEPSG----------WEEPSP 880
              ++SG  G          R   S   SG +  +   ++E+ SG           E  S 
Sbjct: 1832 SVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSR 1891

Query: 881  QSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKS 940
               SR   +  G S+ G   S N  +    D +SQG     E    +   +   S W +S
Sbjct: 1892 ADSSRHSQVGQGQSS-GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQS 1950

Query: 941  TPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES 1000
                  +G+   G  +E   G G   D+ +  +G  +T +++      + +  +   GE 
Sbjct: 1951 R-----DGSRHPGSHHEDRAGHGHSADS-SRQSGTRHTESSSRGQAASSHEQARSSAGER 2004

Query: 1001 DG------PVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWG 1039
             G          +RH      +       +G +G + S  S S G
Sbjct: 2005 HGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEG 2049



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 157/778 (20%), Positives = 256/778 (32%), Gaps = 112/778 (14%)

Query: 319  TSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG-------VNFVVSGREQAQIHNTD 371
            +SR+       ++S  Q ++  + +R    +   +G            +GR QA    +D
Sbjct: 352  SSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSD 411

Query: 372  GPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGP 431
                G++ S    S    EN       G G       +  +ST  R     G  G++   
Sbjct: 412  RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ 471

Query: 432  SGT----DTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFG 487
              T    D+  G++ +   G  G   E +   +    S   ++    +   S GG     
Sbjct: 472  VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531

Query: 488  PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
             + S +     G+  +   SQG      G    +       N+  S  G   +   H   
Sbjct: 532  HEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRH--- 588

Query: 548  ENQGNAQAPCWGRSSSSTGSEVG-GQSTG--SNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604
             ++ ++QA       SS  S+VG GQS+G  ++   GSS S +S  +     H +     
Sbjct: 589  -HEASSQA------DSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG----HSEDSERW 637

Query: 605  QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664
                SR        ++ G  Q Q +  +           G         +S    T+NS 
Sbjct: 638  SGSASR--------NHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSS 689

Query: 665  GWGDAPSQSNQMKSGWGELSAS---TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSS 721
              G A S   Q +S  GE   S    +  D     G    + +++    G R    + ++
Sbjct: 690  S-GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQAT 748

Query: 722  WNENPSKD------QGWG-GGRQPNQGWSSGKNGWGE----------EVDQTKNSNWESS 764
             +E  S+D       G G  G        S ++  GE          +V   K S     
Sbjct: 749  DSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG 808

Query: 765  ASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQ 824
             + P +G  +G  +E        +   AS+ G +  +  P  +  GRQ       H+Q  
Sbjct: 809  WTGPSTGVRQGSHHE---QARDNSRHSASQDGQDTIRGHPGSSRRGRQ----GSHHEQ-- 859

Query: 825  PPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPA--TPKDEEPS--------- 873
                      + SG  G          R   S   SG + A  T ++EE S         
Sbjct: 860  --------SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGS 911

Query: 874  -GWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSK 932
               E  S   ISR      G S  G   S    +    D +S+G     E    +   + 
Sbjct: 912  RHHEASSHADISRHSQAGQGQSE-GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 970

Query: 933  SASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKS 992
              S   +S      +G+      +E   G G   D+   +     TP +A  +    + S
Sbjct: 971  RGSAQEQSR-----HGSRHPRSHHEDRAGHGHSADSSRQS----GTP-HAETSSGGQAAS 1020

Query: 993  MQDGWGESDGPVTGARHPSWEEE---------------EDGGVWNTTGSQGSASSHNS 1035
              +    S G   G+RH    +                 D G W ++GSQ S S  +S
Sbjct: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHS 1078



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 153/793 (19%), Positives = 272/793 (34%), Gaps = 119/793 (15%)

Query: 196  DMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPG---STTSNKGKGSQCQSASSGN 252
            D E W   AS++   S +  + + S  +P S      G   S   ++  G++    SSG 
Sbjct: 3227 DSERWSGSASRNHRGSVQEQSRHGSR-HPRSHHEDRAGHGHSADRSRQSGTRHAETSSGG 3285

Query: 253  ECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWP 312
            +           A S + + S+    +G  + ++       G   G ++ +   +   W 
Sbjct: 3286 QA----------ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQAS-SAVRDSRHWG 3334

Query: 313  ALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDG 372
            +   + +  +G  E  ++ S   VS  GQ    QQS  E+A               +  G
Sbjct: 3335 SSGSQASDSEGHSEESDTQS---VSGHGQAGPHQQSHQESA--------------RDRSG 3377

Query: 373  PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSR------------STDAPSQSTGDRKTG 420
             ++G + S  L   +  E      G    +T R            S  + SQ   D   G
Sbjct: 3378 GRSGRSGSF-LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRG 3436

Query: 421  SVGSWGAARGPSGTDTVSGQSNSGNNGNN-----GKEREDSWKGASVQKSTGSKNDSWDN 475
              GS  + RG  G+        SG++G++      + R D+ +G S  +S   +  + + 
Sbjct: 3437 HPGS--SRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQ 3494

Query: 476  NNRSTGGSWNFGPQ------DSNDNKWGEG--------NKMTSGVSQGEWKQPTGSDELK 521
            +   +  SW+   +       S  ++ G+G            S VSQ    Q    D  +
Sbjct: 3495 SGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSER 3554

Query: 522  IGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSSSTG-----SEVGGQS 573
               WSG    N    A +  +    HP   ++  A       SS  +G     +  GGQ+
Sbjct: 3555 ---WSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 3611

Query: 574  TGSNHKAGSSDSHNSGRRSYRPT---------HPDCQAVLQTLLSRTDLDPRVLSNTGWG 624
              S+ +A SS     G    +           H    + ++    R     +   + G  
Sbjct: 3612 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHS 3671

Query: 625  QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684
            +    Q      +  P  +   +  T G   +A ++  SG +    S   Q +S  G   
Sbjct: 3672 EDSDTQSVSAHGQAGPHQQSHQE-STRG--RSAGRSGRSGSFLYQVSTHEQSESAHGRAG 3728

Query: 685  ASTEWKDPKNTGGWNDYKNNNSSNWG----GGRPDEK---TPSSWNENPSKDQGWGGGR- 736
             ST  +         D   +++S  G     G P  +      S++E      G  G   
Sbjct: 3729 PSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHH 3788

Query: 737  -----QPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASL 791
                 Q     S G++G      +T+N       S+  SG      +E  T  +    S 
Sbjct: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRH-SG---SRHHEASTQADSSRHSQ 3844

Query: 792  ASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGP--PPPPPG 849
            + +G     +RS       RQ +S ++    +  P+        AS +  G        G
Sbjct: 3845 SGQGESAGSRRS------RRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG 3898

Query: 850  NVRPSNS--SWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDP---NSYNY 904
            +  P +S    +S  Q +  + +  +  E     S+S+      G  + G P   +SY+Y
Sbjct: 3899 SRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHY 3958

Query: 905  KNVNLWDKNSQGG 917
            ++     +  Q G
Sbjct: 3959 QSEGTERQKGQSG 3971



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 180/908 (19%), Positives = 305/908 (33%), Gaps = 116/908 (12%)

Query: 210  SSSENTTDNNSASNPGSEKSTLPGSTTSNKGK-GSQCQSASSGNECNLGVWKSDPKAKSV 268
            S  E + D +  S      +T  G + +++G+ GS+  S ++ NE           ++  
Sbjct: 855  SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHH 914

Query: 269  Q-SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
            + SS++    ++  G  ++   +     GS  S  + +   S       E + R     +
Sbjct: 915  EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHS-------EDSERWSGSAS 967

Query: 328  DNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNT-NSLNLSSP 386
             N   SAQ  +   +   +    + AG         Q+   + +    G   +S   +  
Sbjct: 968  RNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARS 1027

Query: 387  NPMENKGMPFGMGLGNTSRSTDAPSQ--STGDRKTGSVGSWGAARGPS-------GTDTV 437
            +P E  G        ++SR +  P +  S+  R +G  GS G+    S        T +V
Sbjct: 1028 SPGERHGSRHQQS-ADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSV 1086

Query: 438  SGQSNSGNNGNNGKEREDSWKGAS--------VQKSTGSKNDSWDNNNR-STG---GSWN 485
            SG    G +  + +E    W G           Q ST  +++S     R STG   GS +
Sbjct: 1087 SGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHH 1146

Query: 486  FGPQDSNDNKWGEGNKMT-----------------------SGVSQGEWKQPTGSDELKI 522
               +DS+ +   +  + T                       SG S       T       
Sbjct: 1147 EQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA 1206

Query: 523  GEWSGPNQPNSSTGAWDNQKGH-PLPENQGNAQAPCWGRSS--SSTGSEVGGQSTGSNHK 579
                  ++  S     D Q G         + +A  W  SS  S  G E    S  S H+
Sbjct: 1207 SHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQ 1266

Query: 580  AGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDL-DPRVLSNTGWGQTQIKQDTVWDIEE 638
              S    +   R     H D    L    SR      R  S  G       Q+       
Sbjct: 1267 GSSVSQDSDSER-----HSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQED--RASH 1319

Query: 639  VPRPEGKSDKGTEGWESAA--------TQTKNSGG--WGDAPSQS--NQMKSGWGELSAS 686
                +     GT   ES++         Q ++S G   G    QS  +   SG G   AS
Sbjct: 1320 GHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQAS 1379

Query: 687  TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGK 746
            +  +D  + G       N+  +      D ++ S+  +     Q      +   G SSG+
Sbjct: 1380 SAVRDSGHRGSSGSQVTNSEGH--SEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437

Query: 747  N-GWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPA 805
            +  +  +V   + S      + P +G  +G ++E        +   AS+ G +  +  P 
Sbjct: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHE---QARNSSRHSASQDGQDTIRGHPG 1494

Query: 806  WNETGRQPNSWNKQ------HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWS 859
             +  GRQ  S+++Q      H         P  + +AS    GP        R ++    
Sbjct: 1495 SSRGGRQ-GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGP--------RSASRQTR 1545

Query: 860  SGPQPATPKDEEPSGWEEPSPQS-ISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGP 918
            +  Q         S   EPS ++  SR   +  G SA G   S    +    D++S+G  
Sbjct: 1546 NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESA-GSKTSRRQGSSVSQDRDSEGHS 1604

Query: 919  APREPNLPTPMTSKSASVWSKS-----TPPAPDNGTSAWGEPNESS--PGWGEMDDTGAS 971
               E    +   +   S   +S      P +     ++ G   ESS   G    + +   
Sbjct: 1605 EDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGG 1664

Query: 972  TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSAS 1031
                    A +    +  S+  Q     +D   TG R       +D  V   +G++GS+ 
Sbjct: 1665 QAASSQEQARSSPGERHGSRHQQSADSSTDSG-TGRR-------QDSSVVGDSGNRGSSG 1716

Query: 1032 SHNSASWG 1039
            S  S S G
Sbjct: 1717 SQASDSEG 1724



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 95/512 (18%), Positives = 164/512 (32%), Gaps = 76/512 (14%)

Query: 204  ASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263
            ++  +  S    T N+S+    S       S     G   Q QSA S      G      
Sbjct: 673  SADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG------ 726

Query: 264  KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323
                 Q+S++  ++ +     R  SG                           + T  +G
Sbjct: 727  ---HGQASSAVRDSGH-----RGSSG--------------------------SQATDSEG 752

Query: 324  ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL 383
              E  ++ S   VS  GQ    QQS  E+A        R              + +S   
Sbjct: 753  HSEDSDTQS---VSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGW 809

Query: 384  SSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNS 443
            + P+    +G        N+  S     Q T     GS     + RG  G+        S
Sbjct: 810  TGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGS-----SRRGRQGSHHEQSVDRS 864

Query: 444  GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMT 503
            G++G++        +  + +  +GS++ S    N           + S D     G++  
Sbjct: 865  GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE----------EQSRDGSRHSGSRHH 914

Query: 504  SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSS 563
               S  +  + + + + +        +  SS     + +GH     + +  A    R S+
Sbjct: 915  EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSA 974

Query: 564  STGSEVGGQSTGSNH--KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNT 621
               S  G +   S+H  +AG   S +S R+S  P H +  +  Q   S            
Sbjct: 975  QEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTP-HAETSSGGQAASSHEQARSSPGERH 1033

Query: 622  GWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWG 681
            G    Q    +      +PR              A++  ++SG WG + SQ++    G  
Sbjct: 1034 GSRHQQSADSS--RHSGIPR------------RQASSAVRDSGHWGSSGSQASD-SEGHS 1078

Query: 682  ELSASTEWKDPKNTGGWNDYKNNNSSNWGGGR 713
            E S +         G        ++ +W GGR
Sbjct: 1079 EESDTQSVSGHGQDGPHQQSHQESARDWSGGR 1110


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 48/113 (42%), Positives = 62/113 (54%), Gaps = 16/113 (14%)

Query: 1226 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------Q 1279
            A + PQ I+PQ    +L+Q     LSP        L  QQ A++ Q  Q+ +F      Q
Sbjct: 117  AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQ 170

Query: 1280 LACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 1332
            L  QLL QQQQQQQ  Q Q++  Q  +QQQ+QQ  +     QQQQQQQQ+ PG
Sbjct: 171  LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 219



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 56/189 (29%), Positives = 70/189 (37%), Gaps = 25/189 (13%)

Query: 1159 SPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPL 1218
            SP  S K  P    LP   L   G        ++  G  H  F    + +      + P 
Sbjct: 75   SPKSSDKQRPLQELLPETKLCICG-------HSSGDGHPHNTFAVPVSVAMMTPQVITPQ 127

Query: 1219 NSSPSLRAQV--PPQF--ISPQVSASMLKQ-----FPNSGLSPGLFNVGPQLSPQQIAML 1269
                 L+ QV  P Q   +  Q  A ML+Q     F           +  Q   QQ    
Sbjct: 128  QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQ 187

Query: 1270 SQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA---------L 1320
             Q  Q  Q Q   Q   QQQQQQQ  Q Q    QA  QQQ+QQ  + ++A         L
Sbjct: 188  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 247

Query: 1321 QQQQQQQQR 1329
            Q QQ QQQ+
Sbjct: 248  QMQQLQQQQ 256



 Score = 31.2 bits (69), Expect = 9.7
 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319
            Q   QQ     Q  Q P  Q A +   QQQQQQQL   Q    Q + Q Q+ Q  + + +
Sbjct: 202  QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 260

Query: 1320 LQQQ 1323
            LQ+Q
Sbjct: 261  LQRQ 264


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 47/109 (43%), Positives = 60/109 (55%), Gaps = 16/109 (14%)

Query: 1230 PQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------QLACQ 1283
            PQ I+PQ    +L+Q     LSP        L  QQ A++ Q  Q+ +F      QL  Q
Sbjct: 4    PQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 57

Query: 1284 LLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 1332
            LL QQQQQQQ  Q Q++  Q  +QQQ+QQ  +     QQQQQQQQ+ PG
Sbjct: 58   LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 102



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 32/79 (40%), Positives = 37/79 (46%), Gaps = 9/79 (11%)

Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319
            Q   QQ     Q  Q  Q Q   Q   QQQQQQQ  Q Q    QA  QQQ+QQ  + ++A
Sbjct: 61   QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120

Query: 1320 ---------LQQQQQQQQR 1329
                     LQ QQ QQQ+
Sbjct: 121  QQLVFQQQLLQMQQLQQQQ 139



 Score = 31.2 bits (69), Expect = 9.7
 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1319
            Q   QQ     Q  Q P  Q A +   QQQQQQQL   Q    Q + Q Q+ Q  + + +
Sbjct: 85   QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 143

Query: 1320 LQQQ 1323
            LQ+Q
Sbjct: 144  LQRQ 147


>gi|11761629 fibrinogen, alpha polypeptide isoform alpha
           preproprotein [Homo sapiens]
          Length = 644

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%)

Query: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458
           G+TS  T + ++S   R   S GSW + + GP  T    G  N G++G  G     +WK 
Sbjct: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323

Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518
           G+S   STGS    W++ +  TG + N  P                  S G W  P  S+
Sbjct: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366

Query: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567
               G W+  +  + STG W ++ G   P++ G+  A    P WG     +G+
Sbjct: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%)

Query: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517
           +G S    TGS+ +S    N S+ GSWN G   S     G  N  +SG       +P  S
Sbjct: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326

Query: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568
                G W   N  +S TG+  NQ  G P P + G      W   SS  GS         
Sbjct: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378

Query: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599
           V G STG  H ++GS    + G  + RP +PD
Sbjct: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 734 GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLAS 793
           GG +  +G S+   G G E +  +N +   S +   SG G  G    G+ G GG A+   
Sbjct: 265 GGNEITRGGSTSY-GTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-- 321

Query: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP 853
           K G      + +WN       S   Q+        P  P+P ++G+W      P  + R 
Sbjct: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQN--------PGSPRPGSTGTWN-----PGSSERG 368

Query: 854 SNSSWSS 860
           S   W+S
Sbjct: 369 SAGHWTS 375



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%)

Query: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696
           G +  GT     +     ++G W      P  +     G      +  WK     P +TG
Sbjct: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332

Query: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753
            WN   +   S  N   G P   +  +W  NP   +    G   ++   SG  G W  E 
Sbjct: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390

Query: 754 DQTKNSNWESSASKPVS-GWG 773
              +  +  S  ++P +  WG
Sbjct: 391 GSFRPDSPGSGNARPNNPDWG 411



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 47/206 (22%), Positives = 76/206 (36%), Gaps = 41/206 (19%)

Query: 345 EQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTS 404
           + + ++E  G N +  G          G  +  T S   S  NP        G     ++
Sbjct: 256 QMRMELERPGGNEITRG----------GSTSYGTGSETESPRNPSSAGSWNSGSSGPGST 305

Query: 405 RSTDAPSQSTGDRKT--------GSVGSWGAARGPSGTDTVS---------GQSNSGNNG 447
            + +  S  TG   T        GS GSW +  G SGT +           G + + N G
Sbjct: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNS--GSSGTGSTGNQNPGSPRPGSTGTWNPG 363

Query: 448 NNGKEREDSWKG-ASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506
           ++ +     W   +SV  STG  +    +    + GS N  P   N+  WG   +++  V
Sbjct: 364 SSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARP---NNPDWGTFEEVSGNV 420

Query: 507 SQGEWKQ--------PTGSDELKIGE 524
           S G  ++          G  EL+ G+
Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGK 446



 Score = 35.8 bits (81), Expect = 0.39
 Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%)

Query: 1527 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1586
            TGS +    +  S G+W   +S    T   +  +      +TW P   G   T   N   
Sbjct: 279  TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336

Query: 1587 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1643
                 S  T       PG   P  +  W+  S+   S   W ++ S   S   W S+ GS
Sbjct: 337  ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392

Query: 1644 VRP 1646
             RP
Sbjct: 393  FRP 395



 Score = 34.7 bits (78), Expect = 0.88
 Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%)

Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
           S   +  N +  G+W + S     GPGS   N NP S+ +   A  + G+S  G+  + N
Sbjct: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335

Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
           S SS   ST  Q                           N   P+ G+T + N   P   
Sbjct: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365

Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
           E           + S ST      +G  +  S GS G AR P+  D  + +  SGN
Sbjct: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%)

Query: 89  REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146
           ++VPP ++   D   +    + P  + +  GG    G    T    NP++A   G+    
Sbjct: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298

Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
            SG          ++     +TW  G+S    T                         S 
Sbjct: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334

Query: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
           ++ SS   +T N +  +  PGS  +  PGS+          +S+ SG   + G W S+  
Sbjct: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391

Query: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297
           +    S  S +   NN   G +  VSG   + PG+
Sbjct: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 32/168 (19%)

Query: 808 ETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP-SNSSWSSGPQPAT 866
           E+ R P+S    +     P       P +SG+ GG     PG+  P S  SW+SG     
Sbjct: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGT-GGTATWKPGSSGPGSTGSWNSGSSGTG 342

Query: 867 PKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLP 926
               +  G   P P S          T  W +P S    +   W   S            
Sbjct: 343 STGNQNPG--SPRPGS----------TGTW-NPGSSERGSAGHWTSESS----------- 378

Query: 927 TPMTSKSASVW-SKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973
               S S   W S+S    PD+  S    PN  +P WG  ++   + +
Sbjct: 379 ---VSGSTGQWHSESGSFRPDSPGSGNARPN--NPDWGTFEEVSGNVS 421



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 21/123 (17%)

Query: 919  APREPNLPTPMTSKSA---SVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGW 975
            +PR P+      S S+   S  +++   +   GT+ W +P  S PG     ++G+S  G 
Sbjct: 285  SPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-KPGSSGPGSTGSWNSGSS--GT 341

Query: 976  GNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS-QGSASSHN 1034
            G+T    P + +P S              TG  +P   E    G W +  S  GS    +
Sbjct: 342  GSTGNQNPGSPRPGS--------------TGTWNPGSSERGSAGHWTSESSVSGSTGQWH 387

Query: 1035 SAS 1037
            S S
Sbjct: 388  SES 390


>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
           preproprotein [Homo sapiens]
          Length = 866

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%)

Query: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458
           G+TS  T + ++S   R   S GSW + + GP  T    G  N G++G  G     +WK 
Sbjct: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323

Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518
           G+S   STGS    W++ +  TG + N  P                  S G W  P  S+
Sbjct: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366

Query: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567
               G W+  +  + STG W ++ G   P++ G+  A    P WG     +G+
Sbjct: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%)

Query: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517
           +G S    TGS+ +S    N S+ GSWN G   S     G  N  +SG       +P  S
Sbjct: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326

Query: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568
                G W   N  +S TG+  NQ  G P P + G      W   SS  GS         
Sbjct: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378

Query: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599
           V G STG  H ++GS    + G  + RP +PD
Sbjct: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 734 GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLAS 793
           GG +  +G S+   G G E +  +N +   S +   SG G  G    G+ G GG A+   
Sbjct: 265 GGNEITRGGSTSY-GTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-- 321

Query: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP 853
           K G      + +WN       S   Q+        P  P+P ++G+W      P  + R 
Sbjct: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQN--------PGSPRPGSTGTWN-----PGSSERG 368

Query: 854 SNSSWSS 860
           S   W+S
Sbjct: 369 SAGHWTS 375



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%)

Query: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696
           G +  GT     +     ++G W      P  +     G      +  WK     P +TG
Sbjct: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332

Query: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753
            WN   +   S  N   G P   +  +W  NP   +    G   ++   SG  G W  E 
Sbjct: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390

Query: 754 DQTKNSNWESSASKPVS-GWG 773
              +  +  S  ++P +  WG
Sbjct: 391 GSFRPDSPGSGNARPNNPDWG 411



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 47/206 (22%), Positives = 76/206 (36%), Gaps = 41/206 (19%)

Query: 345 EQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTS 404
           + + ++E  G N +  G          G  +  T S   S  NP        G     ++
Sbjct: 256 QMRMELERPGGNEITRG----------GSTSYGTGSETESPRNPSSAGSWNSGSSGPGST 305

Query: 405 RSTDAPSQSTGDRKT--------GSVGSWGAARGPSGTDTVS---------GQSNSGNNG 447
            + +  S  TG   T        GS GSW +  G SGT +           G + + N G
Sbjct: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNS--GSSGTGSTGNQNPGSPRPGSTGTWNPG 363

Query: 448 NNGKEREDSWKG-ASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506
           ++ +     W   +SV  STG  +    +    + GS N  P   N+  WG   +++  V
Sbjct: 364 SSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARP---NNPDWGTFEEVSGNV 420

Query: 507 SQGEWKQ--------PTGSDELKIGE 524
           S G  ++          G  EL+ G+
Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGK 446



 Score = 35.8 bits (81), Expect = 0.39
 Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%)

Query: 1527 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1586
            TGS +    +  S G+W   +S    T   +  +      +TW P   G   T   N   
Sbjct: 279  TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336

Query: 1587 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1643
                 S  T       PG   P  +  W+  S+   S   W ++ S   S   W S+ GS
Sbjct: 337  ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392

Query: 1644 VRP 1646
             RP
Sbjct: 393  FRP 395



 Score = 34.7 bits (78), Expect = 0.88
 Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%)

Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
           S   +  N +  G+W + S     GPGS   N NP S+ +   A  + G+S  G+  + N
Sbjct: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335

Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
           S SS   ST  Q                           N   P+ G+T + N   P   
Sbjct: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365

Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
           E           + S ST      +G  +  S GS G AR P+  D  + +  SGN
Sbjct: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%)

Query: 89  REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146
           ++VPP ++   D   +    + P  + +  GG    G    T    NP++A   G+    
Sbjct: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298

Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
            SG          ++     +TW  G+S    T                         S 
Sbjct: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334

Query: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
           ++ SS   +T N +  +  PGS  +  PGS+          +S+ SG   + G W S+  
Sbjct: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391

Query: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297
           +    S  S +   NN   G +  VSG   + PG+
Sbjct: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 32/168 (19%)

Query: 808 ETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP-SNSSWSSGPQPAT 866
           E+ R P+S    +     P       P +SG+ GG     PG+  P S  SW+SG     
Sbjct: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGT-GGTATWKPGSSGPGSTGSWNSGSSGTG 342

Query: 867 PKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLP 926
               +  G   P P S          T  W +P S    +   W   S            
Sbjct: 343 STGNQNPG--SPRPGS----------TGTW-NPGSSERGSAGHWTSESS----------- 378

Query: 927 TPMTSKSASVW-SKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973
               S S   W S+S    PD+  S    PN  +P WG  ++   + +
Sbjct: 379 ---VSGSTGQWHSESGSFRPDSPGSGNARPN--NPDWGTFEEVSGNVS 421



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 21/123 (17%)

Query: 919  APREPNLPTPMTSKSA---SVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGW 975
            +PR P+      S S+   S  +++   +   GT+ W +P  S PG     ++G+S  G 
Sbjct: 285  SPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-KPGSSGPGSTGSWNSGSS--GT 341

Query: 976  GNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS-QGSASSHN 1034
            G+T    P + +P S              TG  +P   E    G W +  S  GS    +
Sbjct: 342  GSTGNQNPGSPRPGS--------------TGTWNPGSSERGSAGHWTSESSVSGSTGQWH 387

Query: 1035 SAS 1037
            S S
Sbjct: 388  SES 390


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
            sapiens]
          Length = 2191

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 160/783 (20%), Positives = 230/783 (29%), Gaps = 158/783 (20%)

Query: 807  NETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866
            N+  +Q     +Q QQQQ  Q P        G+ GG P P P             PQ   
Sbjct: 53   NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD---------MEQPQHGG 103

Query: 867  PKDEEPSGW-EEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQ---------- 915
             KD    G  + P P  +S+  D DD     G+P    Y++  L    +Q          
Sbjct: 104  AKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGG 163

Query: 916  GGPA--PREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973
            GGPA  P   N        S     ++ P    +G        + SPG G M    A+  
Sbjct: 164  GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG-------GQQSPGMGMMHSASAAAA 216

Query: 974  GWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSH 1033
            G       AP +M P   S +           G   P       GG     GS G     
Sbjct: 217  G-------APGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269

Query: 1034 NSASWGQG------GKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV 1087
             + + G G             +  GG    +    A      G+LS         M   +
Sbjct: 270  GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA----GYGVLSSPRQQGGGMM---M 322

Query: 1088 GSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDG 1147
            G        + K A               GF+    ++   + + P   +L    S    
Sbjct: 323  GPGGGGAASLSKAAAG---------SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMR 373

Query: 1148 CLGDEAP--CSPFSPSPSYKLSPSGSTLPNVSLG----AIGTGLNPQ----------NFA 1191
              G   P   SP +P P      S +     + G    A G GL              +A
Sbjct: 374  SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433

Query: 1192 ARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLS 1251
            A Q  SH      T       +   P++     R Q+     +P         +P     
Sbjct: 434  AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493

Query: 1252 PGLFNVGPQLSPQQIAMLSQLP------QIPQFQLACQLLLQQ----------------- 1288
            P     GPQ  P  I +  + P      Q PQ Q +     ++                 
Sbjct: 494  P----PGPQRYP--IGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGY 547

Query: 1289 -QQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHL 1347
             QQ QQ   +Q+     +  Q +   ++     Q QQ   Q   G +  P    G   H 
Sbjct: 548  CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 607

Query: 1348 D-NMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGL 1406
            D N++       LPDL                    G +     GTE+      S     
Sbjct: 608  DLNLIQQERPSSLPDLS-------------------GSIDDLPTGTEATLSSAVSASGST 648

Query: 1407 PSVATQ----------EANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSW 1456
             S   Q           A+ H +     P  +  GSP               +GP   + 
Sbjct: 649  SSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ--------SRSGPISPAS 700

Query: 1457 LPAKSPPTNKIGSKSSNASWPPEFQPGVPWK----------------GIQNIDPESDPYV 1500
            +P    P    GS+S ++S P   Q  +P +                G Q   P   P+ 
Sbjct: 701  IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760

Query: 1501 TPG 1503
            +PG
Sbjct: 761  SPG 763



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 151/724 (20%), Positives = 232/724 (32%), Gaps = 115/724 (15%)

Query: 708  NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767
            ++GG  P+  +PS+    PS+ Q          G      G G      K+   + +A+ 
Sbjct: 374  SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG----LGKDMGAQYAAAS 429

Query: 768  PVSGWGEGGQNEIGTWGNGGNASLASKGGWED--CKRSPAWNETGRQPNSWNKQHQQQQP 825
            P     +   +   + G  G     S+G   D    + P     G  P+S        QP
Sbjct: 430  PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS--------QP 481

Query: 826  PQQPPPPQPEASGSWGGPPPPP-PGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSIS 884
             Q  P P     GS+G P P   P  ++       +G Q    +D   + W+E       
Sbjct: 482  QQSSPYP----GGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKE------- 530

Query: 885  RKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG---GPAPREPNLPTPMTSKSASVWSKST 941
                     + W  P  Y  + V+ + +  Q       P+ P+LP P      S   +  
Sbjct: 531  ---------TFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRY 580

Query: 942  PPAPDNGTSAWGEPNES--SPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGE 999
             P  D     +G  ++   +PG    +D             N     +P+  S+ D  G 
Sbjct: 581  QPQQDMSQEGYGTRSQPPLAPGKPNHED------------LNLIQQERPS--SLPDLSGS 626

Query: 1000 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWM 1059
             D   TG            G   +T SQG  S+   + +       +  S+ GG + S +
Sbjct: 627  IDDLPTGTEATLSSAVSASG---STSSQGDQSNPAQSPFSPHASPHLS-SIPGGPSPSPV 682

Query: 1060 -NPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGF 1118
             +P+    S  G +S      S       GS S+           +      M   +   
Sbjct: 683  GSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQ--- 739

Query: 1119 RPPNSKDMGTTDSGPYFEKLTLP------------FSNQDGCLGDEAPCSPFSPSPSYKL 1166
            R P     G   +GP       P             SN  G  G +   S + P  +Y  
Sbjct: 740  RNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSR 797

Query: 1167 SPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP--VQPLNSSPSL 1224
             P+ S +P+ S    G G+             G+  N+    +G   P    PL   PS 
Sbjct: 798  PPAYSGVPSASYSGPGPGM-------------GISANNQMHGQGPSQPCGAVPLGRMPSA 844

Query: 1225 RAQ---VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLA 1281
              Q    P    S   S+  + Q    G+ P +  V  +      A++       Q +  
Sbjct: 845  GMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR-- 902

Query: 1282 CQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPV 1341
             Q       Q  L+ +    SQ +            S +  Q       P M +S +  V
Sbjct: 903  -QGSFPGMNQSGLMASSSPYSQPMNNSS--------SLMNTQAPPYSMAPAMVNSSAASV 953

Query: 1342 GPKPHLDNMVPNALNVGLP---DLQTKG-PIPGYGSGFSSGGMDYGMVGGK--EAGTESR 1395
            G     D M P    + LP   D + +G P P   S  SS     G    K  E G E  
Sbjct: 954  G---LADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPE 1010

Query: 1396 FKQW 1399
             K W
Sbjct: 1011 RKLW 1014



 Score = 35.0 bits (79), Expect = 0.67
 Identities = 82/347 (23%), Positives = 123/347 (35%), Gaps = 66/347 (19%)

Query: 81  PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVT 140
           P  A+Y+P +   R++ QQD                  G G    P  APG  PN+  + 
Sbjct: 566 PPQAQYLPSQSQQRYQPQQD--------------MSQEGYGTRSQPPLAPG-KPNHEDLN 610

Query: 141 GALLQSE--------SGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192
             L+Q E        SG+  D   G  A  + A S  GS +S  + ++P           
Sbjct: 611 --LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 668

Query: 193 DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS--- 249
             S +   P  +   +   S     N S S P S  S +PGS    +  GSQ +S+S   
Sbjct: 669 HLSSIPGGPSPSPVGSPVGS-----NQSRSGPISPAS-IPGSQMPPQPPGSQSESSSHPA 722

Query: 250 -------------SGNECNLGVWKSDPKAKSVQSSNSTT---ENNNGLGNWRNVSGQDRI 293
                        +G + N  + +  P+      S   +   + + G+ +++  +     
Sbjct: 723 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY 782

Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENA 353
           GP    S + P  N S  PA         G      S     +          Q   +  
Sbjct: 783 GP--QMSQYGPQGNYSRPPAY-------SGVPSASYSGPGPGMGISANNQMHGQGPSQPC 833

Query: 354 GVNFVVSGR-EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMG 399
           G   V  GR   A + N   P  GN +S+  SSP  M  +G P GMG
Sbjct: 834 GA--VPLGRMPSAGMQNRPFP--GNMSSMTPSSPG-MSQQGGP-GMG 874



 Score = 34.7 bits (78), Expect = 0.88
 Identities = 46/188 (24%), Positives = 70/188 (37%), Gaps = 38/188 (20%)

Query: 1313 LARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372
            L + ++  QQQQQQQQ+Q   +    HP+     L      A   G PD++   P  G  
Sbjct: 48   LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPG-PDMEQ--PQHGGA 104

Query: 1373 SGFSSGGM----------------DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANM 1416
               ++GG                 D     G+ AG   R++       GL ++ TQ+   
Sbjct: 105  KDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAG--GRYEH-----PGLGALGTQQP-- 155

Query: 1417 HKNGAIVAPGKTRGGSPYNQFDIIPGDTL------GGHTGPAGDSWLPAKSPPTNKIGSK 1470
                 +  PG   G +   +F+   G         GG  GP  D     +SP    + S 
Sbjct: 156  ----PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211

Query: 1471 SSNASWPP 1478
            S+ A+  P
Sbjct: 212  SAAAAGAP 219


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 65/235 (27%), Positives = 74/235 (31%), Gaps = 27/235 (11%)

Query: 767 KPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826
           KP     +GG    G    G       +G      RSP     G  P   N+      PP
Sbjct: 56  KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115

Query: 827 QQPPPPQPEASGSWGGPPPP--PPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSIS 884
            +P  P P+      GPPPP  P G     + S S    P  P+   P G  +  PQ   
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ--PQGPP 173

Query: 885 RKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWS---KST 941
                  G    G              K  QG P P +P  P P   KS S  S   K  
Sbjct: 174 PPPGKPQGPPPQG-------------GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ 220

Query: 942 PPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDG 996
            P P  G    G P    PG       G    G GN P   P   KP     Q G
Sbjct: 221 GPPPQGGNQPQGPP--PPPG----KPQGPPPQG-GNKPQGPPPPGKPQGPPAQGG 268



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 57/207 (27%), Positives = 67/207 (32%), Gaps = 25/207 (12%)

Query: 805  AWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPP--PPGNVRPSNSSWSSGP 862
            A N  G  P   NK      PP +P  P P+      GPPPP  P G     + S S   
Sbjct: 33   AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92

Query: 863  QPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPRE 922
             P  P+   P G  +P      +      G      P   N           QG P P +
Sbjct: 93   PPGKPQGPPPQGGNQP------QGPPPPPGKPQGPPPQGGN---------RPQGPPPPGK 137

Query: 923  PNLPTPMTSKSASVWS---KSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTP 979
            P  P P   KS S  S   K   P P  G    G P    PG  +           G  P
Sbjct: 138  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--PPPGKPQGPPPQGGKKPQGPPP 195

Query: 980  ANAPNAMKP---NSKSMQDGWGESDGP 1003
               P    P    S+S Q   G+  GP
Sbjct: 196  PGKPQGPPPQGDKSRSSQSPPGKPQGP 222



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 45/170 (26%), Positives = 66/170 (38%), Gaps = 13/170 (7%)

Query: 710 GGGRPDEKTPSSWNENPSKDQGWG--GGRQPNQGWSSGK-NGWGEEVDQTKNSNWESSAS 766
           GG +P    P      P K QG    GG++P      GK  G   + D++++S  +S   
Sbjct: 165 GGNQPQGPPPP-----PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS--QSPPG 217

Query: 767 KPVSGWGEGGQNEIGTWGNGGNAS-LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQP 825
           KP     +GG    G     G       +GG +     P     G      +K    + P
Sbjct: 218 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277

Query: 826 PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQ--PATPKDEEPS 873
           P +P  P  +   +  GPPPP  GN +   +  +  PQ  P  P+   PS
Sbjct: 278 PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 327



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 33/142 (23%), Positives = 44/142 (30%), Gaps = 23/142 (16%)

Query: 767 KPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826
           KP     +GG+   G    G       +G      +SP     G  P   N+      PP
Sbjct: 178 KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237

Query: 827 QQPPPPQPEASGSWGGPPPP-------------------PPGNVRPSNSSWSSGPQ---- 863
            +P  P P+      GPPPP                   PPG  +       + PQ    
Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297

Query: 864 PATPKDEEPSGWEEPSPQSISR 885
           PA    ++P       PQ   R
Sbjct: 298 PAGGNPQQPQAPPAGQPQGPPR 319



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 22/82 (26%), Positives = 29/82 (35%), Gaps = 3/82 (3%)

Query: 48  SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQQDHKVL 104
           ++P    P G    PP  GG+ ++    P G+   PP      P+  PP           
Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 308

Query: 105 LKRGQPPPPSCMLLGGGAGPPP 126
              GQP  P     GG    PP
Sbjct: 309 PPAGQPQGPPRPPQGGRPSRPP 330



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 12/97 (12%)

Query: 54  SPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQ----QDHKVLLK 106
           SP G    PP  GGN  +    P G+   PP      P+  PP  + Q    Q  K    
Sbjct: 92  SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151

Query: 107 RGQP-----PPPSCMLLGGGAGPPPCTAPGANPNNAQ 138
           R  P     PPP       G  PPP    G  P   +
Sbjct: 152 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 28/103 (27%), Positives = 36/103 (34%), Gaps = 13/103 (12%)

Query: 51  TAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQ--------Q 99
           ++ SP G    PP  GGN  +    P G+   PP      P+  PP  + Q        +
Sbjct: 211 SSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270

Query: 100 DHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGA 142
                   G+P  P         GPPP    G NP   Q   A
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPP--PAGGNPQQPQAPPA 311


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 68/248 (27%), Positives = 94/248 (37%), Gaps = 24/248 (9%)

Query: 1133 PYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVS-------LGAIGTGL 1185
            P  ++L        G LG ++     +PS SY L  S    P VS        G  GT +
Sbjct: 1906 PQGQRLRQQLQQSQGMLG-QSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMV 1964

Query: 1186 NPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPLNSSPS--LRAQVPPQ----FISPQVSA 1239
             P   +     +H       + +  L  P + L   PS  +  Q P        + + S 
Sbjct: 1965 PPSYSSQPYQSTH------PSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSH 2018

Query: 1240 SMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQN-- 1297
              L+Q P       +   G Q   +  A+L +  Q  Q Q   Q   QQQQQQQ  Q   
Sbjct: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYH 2078

Query: 1298 --QRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNAL 1355
              Q++  Q +RQQQ+QQ  +     QQQQQQQQ+Q   +        P        P   
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138

Query: 1356 NVGLPDLQ 1363
              GL   Q
Sbjct: 2139 RQGLQQTQ 2146



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 31/78 (39%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQ----QQLLQNQRKIS-QAVRQ-QQEQQL 1313
            Q   QQ     Q  Q  Q Q   Q   QQQQQ    Q   Q+Q +   Q ++Q QQ+QQ 
Sbjct: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQT 2151

Query: 1314 ARMVSALQQQQQQQQRQP 1331
            A +V  LQQQ    Q QP
Sbjct: 2152 AALVRQLQQQLSNTQPQP 2169


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 84/305 (27%), Positives = 100/305 (32%), Gaps = 33/305 (10%)

Query: 710 GGGRPDEKTPSSWNENPSKDQGWG--GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767
           GG +P    P      P K QG    GG +P      GK   G      K+ +  S   K
Sbjct: 64  GGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQ-GPPPQGDKSRSPRSPPGK 117

Query: 768 PVSGWGEGGQNEIGTWGNGGNAS-LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826
           P     +GG    G     G       +GG +     P     G  P   NK    + PP
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP 177

Query: 827 QQPPPPQPEASGSWGGPPPPP--PGNVRPSNSSWSSG-PQPATPKDEEPSGWEEP----S 879
            +P  P P+      GPPPPP  P    P   +   G P P  P+   P G  +     S
Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237

Query: 880 PQSISRKMDIDDGTSAWGDPNSYNYKN--VNLWDKNSQGGPAPREPNLPTPM-TSKSASV 936
           P    +      G    G P                 QG P P +P  P P   SKS S 
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS- 296

Query: 937 WSKSTP-----PAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSK 991
            S+S P     P P  G    G P    PG       G    G GN P   P   KP   
Sbjct: 297 -SRSPPGKPQGPPPQGGNQPQGPP--PPPG----KPQGPPPQG-GNKPQGPPPPGKPQGP 348

Query: 992 SMQDG 996
             Q G
Sbjct: 349 PPQGG 353



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 58/215 (26%), Positives = 70/215 (32%), Gaps = 18/215 (8%)

Query: 805  AWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP--PGNVRPSNSSWSSG- 861
            A N  G  P   NK      PP +P  P P+      GPPPPP  P    P   +   G 
Sbjct: 33   AGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92

Query: 862  PQPATPKDEEPSGWEEPSPQSISRKMD---IDDGTSAWGDPNSYNYKN--VNLWDKNSQG 916
            P P  P+   P G +  SP+S   K        G    G P                 QG
Sbjct: 93   PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152

Query: 917  GPAPREPNLPTPM----TSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGAST 972
             P P +P  P P     +  S S   K   P P  G    G P    PG  +        
Sbjct: 153  PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP--PPPGKPQGPPPQGGN 210

Query: 973  TGWGNTPANAPNAMKP----NSKSMQDGWGESDGP 1003
               G  P   P    P     S+S +   G+  GP
Sbjct: 211  KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 44/169 (26%), Positives = 61/169 (36%), Gaps = 10/169 (5%)

Query: 710 GGGRPDEKTPSSWNENPSKDQGWG--GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASK 767
           GG +P    P      P K QG    GG +P      GK         +K+ +  S   K
Sbjct: 249 GGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK 303

Query: 768 PVSGWGEGGQNEIGTWGNGGNAS-LASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826
           P     +GG    G     G       +GG +     P     G  P   +K    + PP
Sbjct: 304 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPP 363

Query: 827 QQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQ--PATPKDEEPS 873
            +P  P  +   +  GPPPP  GN +   +  +  PQ  P  P+   PS
Sbjct: 364 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 412



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 21/76 (27%)

Query: 51  TAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQP 110
           +A SP G    PP  GGN       P G PP   +  P+  PP    Q  +K    +G P
Sbjct: 234 SARSPPGKPQGPPPQGGNQ------PQGPPPPPGK--PQGPPP----QGGNK---PQGPP 278

Query: 111 PPPSCMLLGGGAGPPP 126
           PP      G   GPPP
Sbjct: 279 PP------GKPQGPPP 288



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 13/94 (13%)

Query: 54  SPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFR-----CQQDHKVLL 105
           SP G    PP  GGN  +    P G+   PP      P+  PP  +      Q D+K   
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS 172

Query: 106 KRGQP-----PPPSCMLLGGGAGPPPCTAPGANP 134
            R  P     PPP       G  PPP    G  P
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 13/97 (13%)

Query: 51  TAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFR-----CQQDHK 102
           ++ SP G    PP  GGN  +    P G+   PP      P+  PP  +      Q D+K
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231

Query: 103 VLLKRGQP-----PPPSCMLLGGGAGPPPCTAPGANP 134
               R  P     PPP       G  PPP    G  P
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 268



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 20/79 (25%)

Query: 48  SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKR 107
           ++P    P G    PP  GG+ ++    P G+P           PP+   Q        +
Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP--------PPQGGNQ-------PQ 316

Query: 108 GQPPPPSCMLLGGGAGPPP 126
           G PPPP     G   GPPP
Sbjct: 317 GPPPPP-----GKPQGPPP 330



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 22/82 (26%), Positives = 29/82 (35%), Gaps = 3/82 (3%)

Query: 48  SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQ---PPSAARYMPREVPPRFRCQQDHKVL 104
           ++P    P G    PP  GG+ ++    P G+   PP      P+  PP           
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 393

Query: 105 LKRGQPPPPSCMLLGGGAGPPP 126
              GQP  P     GG    PP
Sbjct: 394 PPAGQPQGPPRPPQGGRPSRPP 415



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 26/73 (35%), Positives = 30/73 (41%), Gaps = 21/73 (28%)

Query: 54  SPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPP 113
           SP G    PP  GGN       P G PP   +  P+  PP    Q  +K    +G PPP 
Sbjct: 52  SPPGKPQGPPPQGGNQ------PQGPPPPPGK--PQGPPP----QGGNK---PQGPPPP- 95

Query: 114 SCMLLGGGAGPPP 126
                G   GPPP
Sbjct: 96  -----GKPQGPPP 103



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 20/79 (25%)

Query: 48  SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKR 107
           ++P    P G    PP  G N ++    P G+P           PP+   Q        +
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP--------PPQGGNQ-------PQ 254

Query: 108 GQPPPPSCMLLGGGAGPPP 126
           G PPPP     G   GPPP
Sbjct: 255 GPPPPP-----GKPQGPPP 268



 Score = 32.0 bits (71), Expect = 5.7
 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 20/79 (25%)

Query: 48  SQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKR 107
           ++P    P G    PP  G N ++    P G+P           PP+   Q        +
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP--------PPQGGNQ-------PQ 192

Query: 108 GQPPPPSCMLLGGGAGPPP 126
           G PPPP     G   GPPP
Sbjct: 193 GPPPPP-----GKPQGPPP 206


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 47/120 (39%), Positives = 61/120 (50%), Gaps = 22/120 (18%)

Query: 1259 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQR---------KISQAVRQQQ 1309
            P+LS Q +  L QL Q  Q QL  Q  LQQQQQQQL Q Q+         +  Q ++QQQ
Sbjct: 3887 PKLSAQPMGSLQQLQQ--QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQ 3944

Query: 1310 EQQLARMVSALQQQQQQQQ---------RQPGMKHSPSHPVGPKPHLDNMVPNALNVGLP 1360
            +QQL +    LQQQQQQQQ         +Q G+ +     + P+      V  AL  G+P
Sbjct: 3945 QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV--ALGPGMP 4002



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 46/131 (35%), Positives = 61/131 (46%), Gaps = 15/131 (11%)

Query: 1260 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLA----- 1314
            QL  QQ+    Q  Q+ Q Q   Q  LQQQQQQ   Q Q++  Q  +QQQ+QQ+      
Sbjct: 3925 QLQQQQLQQQQQQQQLQQQQ---QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981

Query: 1315 -RMVSALQQQQQQQQRQPGMKHSP----SHP--VGPKPHLDNMVPNALNVGLPDLQTKGP 1367
              ++S  QQQQQQ    PGM   P    S P  +GP   L     N ++  +    T+GP
Sbjct: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041

Query: 1368 IPGYGSGFSSG 1378
                G   + G
Sbjct: 4042 STHQGGPLAIG 4052



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 65/214 (30%), Positives = 87/214 (40%), Gaps = 38/214 (17%)

Query: 1159 SPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQPL 1218
            S SP       G  LP       G GL P      QG   G  G       G+  P QP 
Sbjct: 3622 SQSPRLLTKLPGQLLP-------GHGLQPP-----QGPPGGQAGGLRLTPGGMALPGQP- 3668

Query: 1219 NSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF 1278
               P L   +  Q        +     P+ G  PG       L+ + +   S+L Q  Q 
Sbjct: 3669 -GGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG------NLALRSLGPDSRLLQERQL 3721

Query: 1279 QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPS 1338
            QL       QQQ+ QL Q   K+ Q  +QQQ+QQ      A+QQQQQQ    PG++   +
Sbjct: 3722 QL-------QQQRMQLAQ---KLQQQQQQQQQQQHLLGQVAIQQQQQQ---GPGVQ--TN 3766

Query: 1339 HPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372
              +GPKP    ++P + + GL  +Q   P P  G
Sbjct: 3767 QALGPKP--QGLMPPSSHQGLL-VQQLSPQPPQG 3797



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 63/228 (27%), Positives = 85/228 (37%), Gaps = 45/228 (19%)

Query: 1157 PFSPSPSYKLSPSGSTLPNVSLGA-IGTGLNPQNFAARQGGSHGLFGNSTA--------- 1206
            P   +   +L+P G  LP    G  + T L  Q      GG+  L G S           
Sbjct: 3648 PGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALR 3707

Query: 1207 ---------QSRGLHTPVQPLNSSPSLRAQVPPQ----FISPQVSASMLKQF-----PNS 1248
                     Q R L    Q +  +  L+ Q   Q     +  QV+    +Q       N 
Sbjct: 3708 SLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQ 3767

Query: 1249 GLSPGLFNVGPQLSPQQIAMLS---QLPQIPQFQLA-CQLLLQQQQ-----------QQQ 1293
             L P    + P  S Q + +     Q PQ PQ  L   Q+ + QQQ           +Q 
Sbjct: 3768 ALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQV 3827

Query: 1294 LLQNQRKISQAVRQQQEQQLA--RMVSALQQQQQQQQRQPGMKHSPSH 1339
            L+   R +S     QQ Q L   R+V+A QQQQQQQ +Q G     SH
Sbjct: 3828 LMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH 3875



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 50/180 (27%), Positives = 72/180 (40%), Gaps = 36/180 (20%)

Query: 1259 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVS 1318
            P+   +++ ++++     Q QL  Q+  QQ++   L+   R      +QQQ+QQ      
Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQLD-QVRKQQKEHTNLMAEYRN-----KQQQQQQ------ 3604

Query: 1319 ALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSG--FS 1376
              QQQQQQQQ    +  SPS      P L   +P  L  G      +GP  G   G   +
Sbjct: 3605 --QQQQQQQQHSAVLALSPSQ----SPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658

Query: 1377 SGGMDY-GMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYN 1435
             GGM   G  GG    T               ++A Q+   H  GA    G + G  P N
Sbjct: 3659 PGGMALPGQPGGPFLNT---------------ALAQQQQQQHSGGAGSLAGPSGGFFPGN 3703



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 95/379 (25%), Positives = 140/379 (36%), Gaps = 41/379 (10%)

Query: 1195 GGSHGLFGN--STAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSP 1252
            GGSHG  G+  S+  S   H   QP  S       +    + PQ    ML++   +   P
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ--QPMLERPMQNNTGP 4170

Query: 1253 GLFNVGPQL-SPQQIAMLSQLPQIPQFQLACQLLL-----------QQQQQQQLLQNQRK 1300
                 GP L S Q +  +  +P + Q +   Q +L           QQQQQ Q L  QR+
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230

Query: 1301 I--SQAVRQQQE-QQLARMVSALQQQ---QQQQQRQPGMKHSPSHPVGPKPHLDN----- 1349
            +  SQAVRQ    Q+     S LQ     Q Q    PG +  P   +G  P         
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290

Query: 1350 MVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRF---KQWTSMMEGL 1406
              P AL+ G P L    P P   S               +  TE++       T   +G 
Sbjct: 4291 APPGALSTG-PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG- 4348

Query: 1407 PSVATQEANMHKNGAIVAPGK-TRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTN 1465
            P++      +    A +A    ++G  P++     P D L     P   S +P      N
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWD-----PPDNLAETQKPEQSSLVPGHLDQVN 4403

Query: 1466 -KIGSKSSNASWPPEFQPGVPWKGIQNIDPES--DPYVTPGSVLGGTATSPIVDTDHQLL 1522
             ++  ++S  S   E +      G Q++  E+  +P   PG+        P  +  H LL
Sbjct: 4404 GQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLL 4463

Query: 1523 RDNTTGSNSSLNTSLPSPG 1541
            +      N  L+T   S G
Sbjct: 4464 QKLLRAKNVQLSTGRGSEG 4482



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 19/128 (14%)

Query: 1215 VQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQ 1274
            VQ L+  P    Q P   + P   A + +Q P +        +GPQ  P +  +++Q   
Sbjct: 3787 VQQLSPQPP---QGPQGMLGPAQVAVLQQQHPGA--------LGPQ-GPHRQVLMTQSRV 3834

Query: 1275 IPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMK 1334
            +   QLA       QQ Q L+ ++   +Q  +QQQ+ Q    ++ L   QQ      G  
Sbjct: 3835 LSSPQLA-------QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQP 3887

Query: 1335 HSPSHPVG 1342
               + P+G
Sbjct: 3888 KLSAQPMG 3895



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 41/179 (22%), Positives = 58/179 (32%), Gaps = 18/179 (10%)

Query: 797 WEDCKRSPAWNE--TGRQPNSWNKQHQQQQPPQQPPP------PQPEASGSWG------- 841
           +E+   SP   E  T   P +       ++ P  PPP      P PEAS  +        
Sbjct: 549 FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608

Query: 842 GPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNS 901
            PPP       P  +S  S P   +P    P       P  +SR   +   +     P  
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668

Query: 902 YNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP 960
                ++   + S   P P    L  P      S   + +P +P    S    P E SP
Sbjct: 669 ---SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 31/119 (26%), Positives = 44/119 (36%), Gaps = 12/119 (10%)

Query: 826  PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISR 885
            PQ+PPP Q  A       PP  P   RP + +      P TP+ + P    E       R
Sbjct: 2349 PQEPPPAQALAPS-----PPSHPDIFRPGSYTDPYAQPPLTPRPQPPP--PESCCALPPR 2401

Query: 886  KMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPA 944
             +  D  +     P S +     L  +     P   E   P+P+T +  S    S PP+
Sbjct: 2402 SLPSDPFSRVPASPQSQSSSQSPLTPR-----PLSAEAFCPSPVTPRFQSPDPYSRPPS 2455



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 56/221 (25%), Positives = 84/221 (38%), Gaps = 43/221 (19%)

Query: 1160 PSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPVQP-- 1217
            PSP      +    P  +  ++G GL P    +  G      G     S G HT  +   
Sbjct: 3129 PSPCQFTIATPKVEPAPAANSLGLGLKPGQ--SMMGSRDTRMGTGPFSSSG-HTAEKASF 3185

Query: 1218 -LNSSPSLRAQVPPQFISPQVSASMLKQFPNSG---LSPGLFNVGPQLSPQQIAML-SQL 1272
                 P      P     P  S+ + K    SG   L  G    G +L   + +++ S+L
Sbjct: 3186 GATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASEL 3245

Query: 1273 PQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ-- 1330
            P          LL++      LL++++K       Q++QQL+  +   QQQQQQQQ+   
Sbjct: 3246 P----------LLIED-----LLEHEKK-----ELQKKQQLSAQLQPAQQQQQQQQQHSL 3285

Query: 1331 ---PG------MKHSPSHP--VGPKPHLDNMVPNALNVGLP 1360
               PG      + H  S P   G +  L   +  A   GLP
Sbjct: 3286 LSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLP 3326



 Score = 31.6 bits (70), Expect = 7.4
 Identities = 75/289 (25%), Positives = 108/289 (37%), Gaps = 36/289 (12%)

Query: 1101 AMNLGDFNDIMRKDRSGFRPPN---SKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSP 1157
            A+  G   ++  K  SG +PPN   S   G     P   + T P +  +  L    P  P
Sbjct: 2497 ALPAGPAGELHAKVPSG-QPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP-QP 2554

Query: 1158 FSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQ--NFAARQGGSH------GLFGNSTAQSR 1209
              P P    S  G   P  +LG       PQ  N+    G  H      G    ST +S 
Sbjct: 2555 GLPPPHGINSHFG---PGPTLG------KPQSTNYTVATGNFHPSGSPLGPSSGSTGESY 2605

Query: 1210 GLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGL-SPGLFNVGPQLSPQQIAM 1268
            GL +P++P    PS+     P    P +S    ++   SG+ SP      P         
Sbjct: 2606 GL-SPLRP----PSVLPPPAPDGSLPYLSHGASQR---SGITSPVEKREDPGTGMGSSLA 2657

Query: 1269 LSQLP--QIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQ--QQEQQLARMVSALQQQQ 1324
             ++LP  Q P      Q  L++Q+Q+Q L+      Q  R   +QE++ A   +      
Sbjct: 2658 TAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPP 2717

Query: 1325 QQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 1373
                 +P          G  P       ++L VGLP  +  GPI G GS
Sbjct: 2718 GSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL-VGLPPSKLSGPILGPGS 2765



 Score = 31.6 bits (70), Expect = 7.4
 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 18/78 (23%)

Query: 823  QQPPQQPPPPQPEASGSWGGP--PPPPPGNVR-PSNSSWSSGP-------------QPAT 866
            Q PP+ P PP   ++G   GP  P PPP + + P   S    P              P T
Sbjct: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343

Query: 867  PKDEEPSGWEEPSPQSIS 884
            PK + P+   EP P  +S
Sbjct: 4344 PKPQGPT--LEPPPGRVS 4359


>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
           isoform d [Homo sapiens]
          Length = 756

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 52/247 (21%)

Query: 705 NSSNWGGGRPDEKTPSSWNENPSKDQGWGGG--RQPNQGWSSGKNGWGEEVDQTKNSNWE 762
           N      G P EK   +      + +G GGG  R  N+G   G  G  +           
Sbjct: 495 NEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNR--------- 545

Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQ 822
                   G   GG N  G +   G     S+  W +  R    N       S+N+  QQ
Sbjct: 546 -------GGGSGGGGNYRGGFNRSGGGGY-SQNRWGNNNRD---NNNSNNRGSYNRAPQQ 594

Query: 823 QQPPQQPPPPQPEASGSWGGPPPPP---PGNVRPSNSSW--SSGPQPATPKDEEPSGWEE 877
           Q PPQQPPPPQP        PPPPP   P    P  S++  +S    ++     P+    
Sbjct: 595 QPPPQQPPPPQPPPQ----QPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSY 650

Query: 878 PSPQSISRKMDIDDGTSAWG---------DPNSYNYKNVNLWDKNSQGG--PAPREPNLP 926
             PQ    +   + G  + G          P +YNY         S GG  PAP  P  P
Sbjct: 651 SPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNY--------GSYGGYNPAPYTP--P 700

Query: 927 TPMTSKS 933
            P T+++
Sbjct: 701 PPPTAQT 707



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 36/171 (21%), Positives = 62/171 (36%), Gaps = 16/171 (9%)

Query: 695 TGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754
           +GG  +Y+   + + GGG    +  ++  +N + +      R P Q     +    +   
Sbjct: 549 SGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPP 608

Query: 755 Q--TKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQ 812
           Q      ++  + + P +       N  G+  N    +++S    +     P +N+ G  
Sbjct: 609 QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYS 668

Query: 813 PNSWNKQHQQQQPPQQPPPPQPEASGSWGG-------PPPPPPGNVRPSNS 856
                       PP  PPPP     GS+GG       PPPPP     P  S
Sbjct: 669 QG-------YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPS 712



 Score = 34.7 bits (78), Expect = 0.88
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 5/64 (7%)

Query: 429 RGPSGTDTVSGQSNSGNNGNNGKER---EDSWKGASVQKSTGSKNDSWDNNNRSTGGSWN 485
           RGP G +    Q+  G +G  G  R     S  G   Q   G+ N   DNNN +  GS+N
Sbjct: 532 RGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNR--DNNNSNNRGSYN 589

Query: 486 FGPQ 489
             PQ
Sbjct: 590 RAPQ 593


>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
           isoform a [Homo sapiens]
          Length = 856

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 52/247 (21%)

Query: 705 NSSNWGGGRPDEKTPSSWNENPSKDQGWGGG--RQPNQGWSSGKNGWGEEVDQTKNSNWE 762
           N      G P EK   +      + +G GGG  R  N+G   G  G  +           
Sbjct: 595 NEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNR--------- 645

Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQ 822
                   G   GG N  G +   G     S+  W +  R    N       S+N+  QQ
Sbjct: 646 -------GGGSGGGGNYRGGFNRSGGGGY-SQNRWGNNNRD---NNNSNNRGSYNRAPQQ 694

Query: 823 QQPPQQPPPPQPEASGSWGGPPPPP---PGNVRPSNSSW--SSGPQPATPKDEEPSGWEE 877
           Q PPQQPPPPQP        PPPPP   P    P  S++  +S    ++     P+    
Sbjct: 695 QPPPQQPPPPQPPPQ----QPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSY 750

Query: 878 PSPQSISRKMDIDDGTSAWG---------DPNSYNYKNVNLWDKNSQGG--PAPREPNLP 926
             PQ    +   + G  + G          P +YNY         S GG  PAP  P  P
Sbjct: 751 SPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNY--------GSYGGYNPAPYTP--P 800

Query: 927 TPMTSKS 933
            P T+++
Sbjct: 801 PPPTAQT 807



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 36/171 (21%), Positives = 62/171 (36%), Gaps = 16/171 (9%)

Query: 695 TGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754
           +GG  +Y+   + + GGG    +  ++  +N + +      R P Q     +    +   
Sbjct: 649 SGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPP 708

Query: 755 Q--TKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQ 812
           Q      ++  + + P +       N  G+  N    +++S    +     P +N+ G  
Sbjct: 709 QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYS 768

Query: 813 PNSWNKQHQQQQPPQQPPPPQPEASGSWGG-------PPPPPPGNVRPSNS 856
                       PP  PPPP     GS+GG       PPPPP     P  S
Sbjct: 769 QG-------YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPS 812



 Score = 34.7 bits (78), Expect = 0.88
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 5/64 (7%)

Query: 429 RGPSGTDTVSGQSNSGNNGNNGKER---EDSWKGASVQKSTGSKNDSWDNNNRSTGGSWN 485
           RGP G +    Q+  G +G  G  R     S  G   Q   G+ N   DNNN +  GS+N
Sbjct: 632 RGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNR--DNNNSNNRGSYN 689

Query: 486 FGPQ 489
             PQ
Sbjct: 690 RAPQ 693


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 16/196 (8%)

Query: 654 ESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGR 713
           E + + + N G  G+   + +Q  SG   +        P N  G  + + +       G+
Sbjct: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYM--------PMNNWGSGNGRGSGGGQGSNGQ 510

Query: 714 PDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWG 773
                 S  N+   + QG  GG+  N G  SG N    +   T   +      +P  G G
Sbjct: 511 GSSSHSSGGNQCSGEGQGSRGGQGSN-GQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG 569

Query: 774 EGGQNEIGTW-GNGGNASLASKGGWEDCKRSPAWNETGRQPNSWN------KQHQQQQPP 826
            GG    G   G+GG  +     G    K S    E G+     +      +  QQQ PP
Sbjct: 570 SGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPP 629

Query: 827 QQPPPPQPEASGSWGG 842
             PPPP P  +G  GG
Sbjct: 630 PPPPPPPPPPAGGTGG 645



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 40/130 (30%), Positives = 47/130 (36%), Gaps = 26/130 (20%)

Query: 479 STGGSWNFG----PQDSND-----------NKWGEGNKMTSGVSQGEWKQPTGSDELKIG 523
           S  GS NFG    PQ   D           N WG GN   SG  QG   Q + S      
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520

Query: 524 EWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGS- 582
           + SG  Q  S  G   N +G       G  Q    G+ ++      GGQ  G  H +G  
Sbjct: 521 QCSGEGQ-GSRGGQGSNGQG------SGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGG 573

Query: 583 ---SDSHNSG 589
               D H SG
Sbjct: 574 QGPGDGHGSG 583



 Score = 39.7 bits (91), Expect = 0.027
 Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 19/169 (11%)

Query: 428 ARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG-GSWNF 486
           A  P+    +S + +   +GN G+E     K    +   GS  D    NN  +G G  + 
Sbjct: 447 AEAPNNGARLSSEVSGSGSGNFGEEGNPQGK----EDQEGSGGDYMPMNNWGSGNGRGSG 502

Query: 487 GPQDSN---DNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKG 543
           G Q SN    +    G    SG  QG  +   GS+    G+ SG NQ   S        G
Sbjct: 503 GGQGSNGQGSSSHSSGGNQCSGEGQGS-RGGQGSN----GQGSGGNQ--CSRDGQGTAGG 555

Query: 544 HPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRS 592
           H      G  Q P  G  S        G  +G    +G      SG+ S
Sbjct: 556 H----GSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS 600



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 103/474 (21%), Positives = 159/474 (33%), Gaps = 66/474 (13%)

Query: 388 PMENKGMPFGMGL--GNTSRSTDAPSQSTGDRK-----TGSVGSWGAARGPSGTDTVS-- 438
           PM N G   G G   G  S    + S S+G  +      GS G  G+    SG +  S  
Sbjct: 489 PMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRD 548

Query: 439 GQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGE 498
           GQ  +G +G+ G +R     G+   +  G  + S     +++GG    G    +D     
Sbjct: 549 GQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGS--GGGKNSGGGKGSGSGKGSDGDGER 606

Query: 499 GNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH---PLPENQGNAQA 555
           G  +      G+  Q              P  P   TG      G        ++G A  
Sbjct: 607 GKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRG-ATK 665

Query: 556 PCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDP 615
            C   +     +E+   +    H+A + D        Y P  P    V   L+S +D  P
Sbjct: 666 EC-KEAKEVKDAEIPEGAARGPHRARAFDEDEDD--PYVPMRP---GVATPLVSSSDYMP 719

Query: 616 RVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQ 675
               N    + +  +    D         +           A  T       D  S+S+ 
Sbjct: 720 MAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDY 779

Query: 676 MKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNEN-------PSK 728
           M    G   A    K+P+N  G +  K + SS +    P   +P   N+N       P K
Sbjct: 780 MFMAPG---AGAIPKNPRNPQGGSSSK-SWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGK 835

Query: 729 DQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
             G G  ++ +  W        +  D     + E S SKP               G+GG+
Sbjct: 836 FLGRGLDKEVSYNW--------DPKDAASKPSGEGSFSKP---------------GDGGS 872

Query: 789 ASLASKGGWEDCKRSPAWNETGRQPNSWN---KQHQQQQPPQQPPPPQPEASGS 839
            S  S          P  N+  ++PN  +   K ++ +  PQ+P   Q EA  S
Sbjct: 873 PSKPS-------DHEPPKNK-AKRPNRLSFITKGYKIKPKPQKPTHEQREADSS 918



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 6/131 (4%)

Query: 952  WGEPNE--SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGES----DGPVT 1005
            WG  N   S  G G      +S +  GN  +      +    S   G G +    DG  T
Sbjct: 493  WGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGT 552

Query: 1006 GARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQ 1065
               H S   +  GG   + G QG    H S      G  +   S KG + D       K+
Sbjct: 553  AGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKK 612

Query: 1066 FSNMGLLSQTE 1076
             S  G L+Q++
Sbjct: 613  RSYFGKLTQSK 623



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 48/236 (20%), Positives = 77/236 (32%), Gaps = 20/236 (8%)

Query: 643 EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYK 702
           +G + +G+    S   Q    G        SN   SG  + S   +     +  G     
Sbjct: 505 QGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRP 564

Query: 703 NNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGR----QPNQGWSSGKNGWGEEVDQTKN 758
                + GG  P +   S   +N    +G G G+       +G S  K  +  ++ Q+K 
Sbjct: 565 GGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQ 624

Query: 759 SNWESSASKPVSGWGEGGQNEIGTWGNGGNASL---ASKGGWEDCKRSPAWNE------T 809
                    P      GG    G   +GG   L     +G  ++CK +    +       
Sbjct: 625 QQMPPPPPPPPPPPPAGGTG--GKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGA 682

Query: 810 GRQPN---SWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGP 862
            R P+   ++++       P +P    P  S S     P  P NV  S    S  P
Sbjct: 683 ARGPHRARAFDEDEDDPYVPMRPGVATPLVSSS--DYMPMAPQNVSASKKRHSRSP 736


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 66/236 (27%), Positives = 99/236 (41%), Gaps = 35/236 (14%)

Query: 1160 PSPSY---KLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTPV- 1215
            PSPS+     SP  S +P V+ G  G      N+  + G S          ++G H  V 
Sbjct: 481  PSPSFGQQTFSPQSSPMPGVA-GGSGQSKVMANYMYKAGPS----------AQGGHLDVL 529

Query: 1216 ---QPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQL 1272
               +P + S S      P     Q +   L  F +   +  + +V P  +   +   +Q 
Sbjct: 530  MQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQ 589

Query: 1273 PQIPQFQLACQLLLQQQQQQQLLQNQRKISQ--AVRQQQEQQLARMVSALQQQQQQQQRQ 1330
             Q  Q Q   Q   QQQQQQQ  Q Q++  Q  ++  QQ+QQ    +SA QQQQQQQQ+Q
Sbjct: 590  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQ 649

Query: 1331 PGMKH--------------SPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1372
               +                P+  +  +P L + +P    + L  +Q + PI G G
Sbjct: 650  QQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQ-PIAGMG 704



 Score = 35.4 bits (80), Expect = 0.51
 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 21/127 (16%)

Query: 1234 SPQVSASMLKQFPNSGLSPGLFNVGPQLSPQ---------------QIAMLSQLPQIPQF 1278
            +P+ S  M K    S  SPGL   GP  SPQ                ++  S +P +PQ 
Sbjct: 352  TPRPSLPMEKIVIKSEYSPGLTQ-GPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQS 410

Query: 1279 QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPS 1338
            Q   Q         + L + +++S A  QQ +Q  A      + QQ QQQ QP    +  
Sbjct: 411  QAQPQT---GSGASRALPSWQEVSHA--QQLKQIAANRQQHARMQQHQQQHQPTNWSALP 465

Query: 1339 HPVGPKP 1345
               GP P
Sbjct: 466  SSAGPSP 472



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 27/143 (18%)

Query: 1214 PVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLF-------------NVGPQ 1260
            P Q L S P LR+ +P Q    ++    ++  P +G+   +              N GP 
Sbjct: 670  PAQSLPSQPLLRSPLPLQ---QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPS 726

Query: 1261 LSPQQIA--------MLSQLPQIPQFQLACQLLLQQQ---QQQQLLQNQRKISQAVRQQQ 1309
             SP   +        M SQ   + Q  +  +  LQ+Q   Q+QQLL  Q+ ++ A +   
Sbjct: 727  PSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAP 786

Query: 1310 EQQLARMVSALQQQQQQQQRQPG 1332
            + Q+ R +S      + Q+R  G
Sbjct: 787  QDQINRHLSRPPPDYKDQRRNVG 809



 Score = 31.2 bits (69), Expect = 9.7
 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 31/177 (17%)

Query: 1193 RQGGSHGLFGNSTAQSRGLHTPVQPLNSSPSL--------RAQVPPQFISPQVSASMLKQ 1244
            RQG +  LF  ++ Q+      V P  + PSL        + Q   Q    Q      +Q
Sbjct: 552  RQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQ 611

Query: 1245 FPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQA 1304
                       ++  Q   QQ + +S   Q  Q Q   Q   QQQQQQQ  Q Q     A
Sbjct: 612  QQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPA 671

Query: 1305 --------------------VRQQQEQQLARM---VSALQQQQQQQQRQPGMKHSPS 1338
                                ++Q Q Q +A M   VS  Q+Q Q          SPS
Sbjct: 672  QSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPS 728



 Score = 31.2 bits (69), Expect = 9.7
 Identities = 25/149 (16%), Positives = 64/149 (42%), Gaps = 16/149 (10%)

Query: 3   EKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSP 62
           +++Q++++Q  + ++++++ +++++  Q+  +Q++ +    +       +A         
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647

Query: 63  PVNGGNNAKRVAVPNGQPPSA--ARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCM---- 116
                   ++      Q PS+  A+ +P +   R       K+LL++ Q  P + M    
Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV 707

Query: 117 ----------LLGGGAGPPPCTAPGANPN 135
                     ++G   GP P   P +NPN
Sbjct: 708 SQQQRQDQHSVVGQNTGPSPSPNPCSNPN 736


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
            sapiens]
          Length = 247

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 57/213 (26%), Positives = 71/213 (33%), Gaps = 16/213 (7%)

Query: 810  GRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP--PGNVRPSNSSWSSGPQPATP 867
            GR+P   N+  +   PP +P  P P+      GPPPPP  P    P   + S GP P   
Sbjct: 38   GRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG 97

Query: 868  KDEEP-------SGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAP 920
            K E P       S    P P    R        S    P     +       N   GP P
Sbjct: 98   KPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPP 157

Query: 921  R--EPNLPTPMT-SKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGN 977
               +P  P P   +KS S  ++S P  P       G   +  P  G+    G    G   
Sbjct: 158  HPGKPEGPPPQEGNKSRS--ARSPPGKPQGPPQQEGNKPQGPPPPGK--PQGPPPAGGNP 213

Query: 978  TPANAPNAMKPNSKSMQDGWGESDGPVTGARHP 1010
                AP A KP         G    P  G + P
Sbjct: 214  QQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 46/176 (26%), Positives = 58/176 (32%), Gaps = 25/176 (14%)

Query: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVR- 852
           +GG +     P   +  R P     Q Q   PP   P   P   G+    PPPPPG    
Sbjct: 84  QGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPER 143

Query: 853 --PSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLW 910
             P   + S GP P       P   E P PQ  ++        S  G P     +  N  
Sbjct: 144 PPPQGGNQSQGPPP------HPGKPEGPPPQEGNKSR---SARSPPGKPQGPPQQEGN-- 192

Query: 911 DKNSQGGPAPREPNLP-----TPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPG 961
               QG P P +P  P      P   ++        PP P  G    G P   + G
Sbjct: 193 --KPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQG----GRPPRPAQG 242



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 41/172 (23%), Positives = 55/172 (31%), Gaps = 20/172 (11%)

Query: 712 GRPDEKTPSSWNEN---------PSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWE 762
           G+P+ + P   N++         P +    GG +        GK          ++    
Sbjct: 76  GKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP 135

Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNAS--LASKGGWEDCKRSPAWNETGRQPNSWNKQH 820
               KP     +GG    G   + G        +G      RSP     G      NK  
Sbjct: 136 PPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQ 195

Query: 821 QQQQP--PQQPPP-------PQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQ 863
               P  PQ PPP       PQ   +G   GPPPPP G   P  +     PQ
Sbjct: 196 GPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPPQ 247



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 6/85 (7%)

Query: 57  GSSPSPPVNGGNNAKRVAVPNGQP---PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPP 113
           G    PP   GN ++    P G+P   P      P+  PP  + Q         G P  P
Sbjct: 160 GKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPA---GGNPQQP 216

Query: 114 SCMLLGGGAGPPPCTAPGANPNNAQ 138
                G   GPPP    G  P  AQ
Sbjct: 217 QAPPAGKPQGPPPPPQGGRPPRPAQ 241



 Score = 32.0 bits (71), Expect = 5.7
 Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 17/74 (22%)

Query: 57  GSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQP--PPPS 114
           G    PP  GGN ++    P G+P         E PP     Q H+     G+P  PPP 
Sbjct: 97  GKPERPPPQGGNQSQGTPPPPGKP---------ERPPPQGGNQSHRPPPPPGKPERPPPQ 147

Query: 115 CMLLGG--GAGPPP 126
               GG    GPPP
Sbjct: 148 ----GGNQSQGPPP 157


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.125    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,420,952
Number of Sequences: 37866
Number of extensions: 5874815
Number of successful extensions: 47032
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 399
Number of HSP's successfully gapped in prelim test: 1131
Number of HSP's that attempted gapping in prelim test: 25335
Number of HSP's gapped (non-prelim): 14319
length of query: 1833
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1716
effective length of database: 13,817,196
effective search space: 23710308336
effective search space used: 23710308336
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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