Guide to the Human Genome
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Name: MED12 Sequence: fasta or formatted (2177aa) NCBI GI: 110347429
Description:

mediator complex subunit 12

Referenced in:

Nuclear Receptors
RNA Polymerase and General Transcription Factors

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8        127           2
 C cysteine            2.2         48           2
 D aspartate           4.6        100           3
 E glutamate           5.9        128           3
 F phenylalanine       3.2         69           2
 G glycine             6.2        134           4
 H histidine           2.6         57           2
 I isoleucine          3.8         82           3
 K lysine              4.9        106           3
 L leucine            10.7        233           3
 M methionine          2.2         47           1
 N asparagine          3.0         66           2
 P proline             6.9        151           3
 Q glutamine           9.7        212          26
 R arginine            5.1        111           3
 S serine              8.9        193           4
 T threonine           5.6        122           2
 V valine              5.3        116           2
 W tryptophan          0.9         20           1
 Y tyrosine            2.5         55           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mediator complex subunit 12 
MED12L                0.549   mediator of RNA polymerase II transcription, subunit...
MLL2                  0.026   myeloid/lymphoid or mixed-lineage leukemia 2 
MAML2                 0.026   mastermind-like 2 
FOXP2                 0.022   forkhead box P2 isoform I 
FOXP2                 0.022   forkhead box P2 isoform II 
FOXP2                 0.021   forkhead box P2 isoform III 
MED15                 0.020   mediator complex subunit 15 isoform a 
MED15                 0.020   mediator complex subunit 15 isoform b 
ZNF853                0.019   zinc finger protein 853 
TOX3                  0.016   TOX high mobility group box family member 3 isoform...
TOX3                  0.016   TOX high mobility group box family member 3 isoform...
CREBBP                0.016   CREB binding protein isoform b 
CREBBP                0.016   CREB binding protein isoform a 
PAXIP1                0.016   PAX interacting protein 1 
BMP2K                 0.015   BMP-2 inducible kinase isoform a 
BMP2K                 0.015   BMP-2 inducible kinase isoform b 
TBP                   0.014   TATA box binding protein 
EP400                 0.014   E1A binding protein p400 
NCOA3                 0.014   nuclear receptor coactivator 3 isoform a 
AAK1                  0.013   AP2 associated kinase 1 
BRD4                  0.013   bromodomain-containing protein 4 isoform long 
EP300                 0.013   E1A binding protein p300 
NCOA3                 0.013   nuclear receptor coactivator 3 isoform b 
ARID1A                0.012   AT rich interactive domain 1A isoform a 
ARID1A                0.012   AT rich interactive domain 1A isoform b 
PHC1                  0.012   polyhomeotic 1-like 
KIAA2018              0.012   hypothetical protein LOC205717 
LOC100133758          0.011   PREDICTED: hypothetical protein, partial 
TRERF1                0.011   transcriptional regulating factor 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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