Guide to the Human Genome
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Search of human proteins with 239757729

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757729 PREDICTED: hypothetical protein [Homo sapiens]
         (329 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757729 PREDICTED: hypothetical protein [Homo sapiens]           700   0.0  
gi|239752222 PREDICTED: hypothetical protein [Homo sapiens]           700   0.0  
gi|239746743 PREDICTED: hypothetical protein [Homo sapiens]           700   0.0  
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    67   2e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    65   8e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    63   3e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     61   2e-09
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        60   3e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   59   6e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   59   6e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   59   6e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    59   6e-09
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       59   8e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    58   1e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    58   1e-08
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    56   4e-08
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    56   4e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     55   7e-08
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       55   1e-07
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         54   1e-07
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    53   4e-07
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    53   4e-07
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       52   6e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          52   6e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          52   6e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    52   7e-07
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi...    52   7e-07
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi...    52   7e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  52   9e-07
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]       51   1e-06

>gi|239757729 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score =  700 bits (1807), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT 60
           MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT
Sbjct: 1   MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT 60

Query: 61  SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC 120
           SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC
Sbjct: 61  SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC 120

Query: 121 SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR 180
           SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR
Sbjct: 121 SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR 180

Query: 181 PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL 240
           PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL
Sbjct: 181 PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL 240

Query: 241 ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL 300
           ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL
Sbjct: 241 ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL 300

Query: 301 WLTERETPHSLLLCLSPSHALSPCKAQGY 329
           WLTERETPHSLLLCLSPSHALSPCKAQGY
Sbjct: 301 WLTERETPHSLLLCLSPSHALSPCKAQGY 329


>gi|239752222 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score =  700 bits (1807), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT 60
           MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT
Sbjct: 1   MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT 60

Query: 61  SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC 120
           SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC
Sbjct: 61  SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC 120

Query: 121 SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR 180
           SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR
Sbjct: 121 SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR 180

Query: 181 PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL 240
           PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL
Sbjct: 181 PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL 240

Query: 241 ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL 300
           ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL
Sbjct: 241 ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL 300

Query: 301 WLTERETPHSLLLCLSPSHALSPCKAQGY 329
           WLTERETPHSLLLCLSPSHALSPCKAQGY
Sbjct: 301 WLTERETPHSLLLCLSPSHALSPCKAQGY 329


>gi|239746743 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score =  700 bits (1807), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT 60
           MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT
Sbjct: 1   MPTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQT 60

Query: 61  SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC 120
           SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC
Sbjct: 61  SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRC 120

Query: 121 SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR 180
           SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR
Sbjct: 121 SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRR 180

Query: 181 PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL 240
           PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL
Sbjct: 181 PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL 240

Query: 241 ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL 300
           ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL
Sbjct: 241 ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL 300

Query: 301 WLTERETPHSLLLCLSPSHALSPCKAQGY 329
           WLTERETPHSLLLCLSPSHALSPCKAQGY
Sbjct: 301 WLTERETPHSLLLCLSPSHALSPCKAQGY 329


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 76/278 (27%), Positives = 106/278 (38%), Gaps = 40/278 (14%)

Query: 19  QSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPR 78
           Q PP P +  G  P+ D+   PRS  PP  P+      G Q   P P       PP  P+
Sbjct: 69  QGPPPPGKPQGPPPQGDKSRSPRS--PPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQ 124

Query: 79  RGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPARRP 138
            G R +        P P  +P G   PPP G+K   P   R   G  + P   G    + 
Sbjct: 125 GGNRPQ-------GPPPPGKPQG---PPPQGDKSRSP---RSPPGKPQGPPPQGGNQPQG 171

Query: 139 PAHIPAQPRWPRLQPVAKRRARPVPPGLPGAP------KQAALTPGRRPLTPAAFAPKAS 192
           P   P +P+ P  Q   K+   P PPG P  P       +++ +P  +P  P    P+  
Sbjct: 172 PPPPPGKPQGPPPQG-GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGP---PPQGG 227

Query: 193 RDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLASS--------- 243
              Q         +G   + G   Q        QG  A   GG  S  A S         
Sbjct: 228 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPA--QGGSKSQSARSPPGKPQGPP 285

Query: 244 REQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIP 281
           +++ ++P   P P+  +P   +APPA    P+G P  P
Sbjct: 286 QQEGNNPQGPPPPAGGNPQQPQAPPAGQ--PQGPPRPP 321



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 41/146 (28%), Positives = 50/146 (34%), Gaps = 18/146 (12%)

Query: 48  SPEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPP 107
           SP+ G K  GP      P+ P    PP    + + G P       P P    + +   PP
Sbjct: 40  SPQGGNKPQGPPPPPGKPQGP----PPQGGNKPQ-GPPPPGKPQGPPPQGDKSRSPRSPP 94

Query: 108 TGEKQPRPHGFRCSHGSKRAPALLGAPARRPP--------AHIPAQPRWPRLQPVAKRRA 159
              + P P G     G    P   G P   PP           P +P+ P  Q    R  
Sbjct: 95  GKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151

Query: 160 RPVPPGLP-GAPKQAALTPGRRPLTP 184
           R  PPG P G P Q    P   P  P
Sbjct: 152 RS-PPGKPQGPPPQGGNQPQGPPPPP 176



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 15/103 (14%)

Query: 21  PPSPQRDSGLTPER-DRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRR 79
           PP P +  G  P+  ++P  P    PP    +G  A G   S  +   PG    P  P +
Sbjct: 234 PPPPGKPQGPPPQGGNKPQGP----PPPGKPQGPPAQGGSKSQSARSPPG---KPQGPPQ 286

Query: 80  GRRGRPTQEVCPAPG----PCAQPAGT---CPPPPTGEKQPRP 115
                P     PA G    P A PAG     P PP G +  RP
Sbjct: 287 QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 83/311 (26%), Positives = 127/311 (40%), Gaps = 52/311 (16%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPC 75
            P   +PPSP+     +P +  P  P +  P  SP KG+  + P   AP+P  P + TPP 
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPP--SP-KGSPGTPPPKGAPTP--PAV-TPP- 1341

Query: 76   SPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPA 135
            SP    +G PT    PA  P ++     P  P+ ++ P P     SH  K  PA+     
Sbjct: 1342 SP----KGTPT---LPATTPSSKGG---PTTPSSKEGPTPPAATPSH--KGGPAMTPPSP 1389

Query: 136  RRPPAHIPA---QPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAPKAS 192
            +R PA IP+    P  P + P++ ++A   P       ++ A TP +  LTP A  P + 
Sbjct: 1390 KRGPA-IPSPKGDPTSPAVIPLSPKKAPATP-----VTREGAATPSKGDLTPPAVTPVSL 1443

Query: 193  RDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLASSREQTHSPHL 252
            +    T +          + GPA         S+G     A   PS       +  +   
Sbjct: 1444 KKAPATSA---------PKGGPA------TPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488

Query: 253  YPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSLWLTERETPHSLL 312
             P  + ++P+   AP   +V P     +PA        +   AT     L  ++TP +  
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT-----LLSKKTPAT-- 1541

Query: 313  LCLSPSHALSP 323
              L+P  AL P
Sbjct: 1542 --LAPKEALIP 1550



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 80/307 (26%), Positives = 107/307 (34%), Gaps = 50/307 (16%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKA----SGPQTSAPSPRDP--G 69
            P   +PPSP+      P +  P  P +  P  SP+ G         P T A +P  P  G
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPP--SPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 70   LHTPPC------------SPRRGR-----RGRPTQEVCPAPGPCA------------QPA 100
            L TPP             SP+ G      +G PT      P P               PA
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222

Query: 101  GTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRAR 160
             T P P  G   P P G   +  +   P+  G PA  PP   P  P      P + +   
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGPATPPPKGAPTPPA---ATPPSLKGGL 1278

Query: 161  PVPPGLPGAPKQAALTPGRRPLTPAAFAPK-ASRDQQVTDSTTICQRGLIEETGPARQIS 219
              PP   GAP  A +TP      PA   PK A      T  +     G     G     +
Sbjct: 1279 ATPPH-KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337

Query: 220  DLCEVSQGVGAFRAGGCPSSLASSR--EQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGR 277
                  +G         P++  SS+    T S    P+P +++PS    P     +P+  
Sbjct: 1338 VTPPSPKGTPTL-----PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392

Query: 278  PGIPAHK 284
            P IP+ K
Sbjct: 1393 PAIPSPK 1399



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 78/303 (25%), Positives = 108/303 (35%), Gaps = 49/303 (16%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGP---------QTSAPSPR 66
            P   +PPSP+     TP       P +  PP SP KG+ A+ P           + PSP+
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPP-SP-KGSPAATPLPKGAPTTPAATLPSPK 1068

Query: 67   D-------PGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFR 119
                     G  TPP +     +G P     P+P     P    PP P G     PH   
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPAT---PSPKGAPMPPAATPPSPKGGLATPPHKGA 1125

Query: 120  CSHGSKRAPALLGAPARRPPAHIP----AQPRWPR--LQPVAKRRARPVPPGLPGAPKQA 173
             +  +   P+  G  A  PP   P    A P  P+  L     + A   P   P +PK  
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185

Query: 174  ALTPGRR--PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAF 231
              TP  +  P TPAA  P + +    T S          +  P    +       G+   
Sbjct: 1186 LATPSPKGAPTTPAA-TPPSPKGGLATPS---------PKGAPTTPAATPPSPKGGLATP 1235

Query: 232  RAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTP---RGRPGIPAHKLGAS 288
               G P++ A++      P     P++  P     PPA   TP   +G    P HK   +
Sbjct: 1236 SPKGAPTTPAAT-----PPSPKGGPATPPPKGAPTPPA--ATPPSLKGGLATPPHKGAPN 1288

Query: 289  SAV 291
             AV
Sbjct: 1289 PAV 1291



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 62/201 (30%), Positives = 79/201 (39%), Gaps = 34/201 (16%)

Query: 2    PTERILNLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTS 61
            PT  ++NL    +  +  + P+P++   L+     P   R+   P    KG  AS     
Sbjct: 886  PTPSVVNL---PFPKEGPATPAPKQAPALSMTSSSPKKARATPAP----KGIPAS----- 933

Query: 62   APSPRDPGLHTPPCSPRRGRRGRP-TQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGF-- 118
             PSP+  G  TPP +     +G P T     AP P   PA T P P  G   P P G   
Sbjct: 934  -PSPK--GAPTPPAATPPSPKGGPATPSPKWAPTP---PAATPPSPKGGPATPSPKGAPT 987

Query: 119  ------RCSHGSKRAPALLGAPARRPPAHIPAQPRW-PRLQPVAKRRARP---VPPGLPG 168
                      G    P+  GAP   PPA  P  P+  P   P  K  + P    PP   G
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPT--PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045

Query: 169  APKQAALTPGRRPLTPAAFAP 189
            +P    L  G  P TPAA  P
Sbjct: 1046 SPAATPLPKG-APTTPAATLP 1065



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 76/306 (24%), Positives = 99/306 (32%), Gaps = 100/306 (32%)

Query: 11   GKNYKPQDQSPPSPQRDSGLTPERDRPDWP-RSFKPPLSPEK------------GTKASG 57
            G +  PQ + PP+ +  +G       PD P  +   P+SP +            G+K S 
Sbjct: 798  GVSVSPQTKRPPTKKGSAG-------PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP 850

Query: 58   PQTSAPSPRDP-GLHTP----PCSPRRGR---RGRPTQEVCPAPGPCAQPAGTCPP---- 105
              T +P+P  P G  TP    P SP+      +  PT  V   P P   PA   P     
Sbjct: 851  ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA 910

Query: 106  -------PPTGEKQPRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRR 158
                   P      P P G   S   K AP         PPA  P  P+     P  K  
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSPKGAPT--------PPAATPPSPKGGPATPSPKWA 962

Query: 159  ARPVPPGLPGAPKQAALTPGRR--PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPAR 216
              P P   P +PK    TP  +  P  PAA  P                     + GPA 
Sbjct: 963  PTP-PAATPPSPKGGPATPSPKGAPTPPAATPPSP-------------------KGGPA- 1001

Query: 217  QISDLCEVSQGVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRG 276
                                          T SP   P+P + +P S +  PA +  P+G
Sbjct: 1002 ------------------------------TPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031

Query: 277  RPGIPA 282
                PA
Sbjct: 1032 ASTPPA 1037



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 62/297 (20%), Positives = 106/297 (35%), Gaps = 28/297 (9%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPC 75
            P  + PP+P++ +  +  +  P  P     P  P     A  P +    P  P     P 
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP-----AVIPSSPKEVPATPSSRRDPI 1527

Query: 76   SPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRA---PALLG 132
            +P      + T            PA T P P      P P     +  SK A   PA+  
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV-- 1585

Query: 133  APARRPPAHIPAQPRWPRLQPVAKRRARPVPPGL-PGAPKQAALTPGRR--PLTPAAFAP 189
             P+    A  P +   P        +  P PP + P +P++   TP  +  P +P    P
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV-TP 1644

Query: 190  KASRDQQVTDSTTICQ---------RGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSL 240
             + +D   + ++  C+         +GL  + GP      L   +               
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704

Query: 241  ASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATY 297
             + +    SP + P PS+ + S     P ++V P   P +P  K  + +A  ++A++
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSK---GPLSTVAP--APLLPVQKDSSKTAKGKDASH 1756



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 63/284 (22%), Positives = 97/284 (34%), Gaps = 39/284 (13%)

Query: 48   SPEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPP 107
            SP+K      P+ +  +P      +PP       +G P+ +    P     P+    P P
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616

Query: 108  TGEKQPRPHGFRCSHGSKRAPALLGAPARRP--PAHIPAQPRWPRLQPVAKRRARPVPPG 165
                 P P            PA  G P   P  P+ +   P  P    V  +    VP  
Sbjct: 1617 PAVTPPSP------EKGPATPAPKGTPTSPPVTPSSLKDSPTSP--ASVTCKMGATVPQA 1668

Query: 166  LPGAPKQAALTPGRRPL-------TPAAFAPKASRDQQVTDSTT---IC--------QRG 207
              G P +   T  +  L       TP   AP     Q    S T   IC         +G
Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728

Query: 208  LIEETGPARQI---SDLCEVSQGVGAFRAGGCPSSLASSREQT-----HSPHLYPSPSSS 259
             +    PA  +    D  + ++G  A  +   P +   S+  T         + P P S+
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788

Query: 260  SPSSWEAPPAN-SVTPRGRPGIPAHK--LGASSAVCQEATYKSL 300
            S S+  +PP +  + P   P +P  +  L +S  +  E+  K L
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPL 1832


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 53/177 (29%), Positives = 63/177 (35%), Gaps = 13/177 (7%)

Query: 22  PSPQRDSGLT------PERDRPDWP--RSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTP 73
           PSPQ  + L       P    P  P    F PP SP     A+ P  + PS   P L  P
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707

Query: 74  PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGA 133
           P  P              AP P A P    PP P       P     +    R P LL A
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS----ATPPPRVPPLLAA 763

Query: 134 PARRPPAHIPAQ-PRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAP 189
           P  + P   PA  P  P  +P  +       P L   P   A  PG+ P +P+A  P
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 73/263 (27%), Positives = 93/263 (35%), Gaps = 30/263 (11%)

Query: 20  SPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRR 79
           +PPS Q     TP       P    P L+P     AS P T+      P L TPPC    
Sbjct: 519 APPSLQ-----TPPASLTTPPLENLPSLAPPPLQTASAPLTT------PHLETPPCPAPC 567

Query: 80  GRRGRPTQEVCP---APGPCAQPAGTCPP---PPTGEKQPRPHGFRCSHGSKRAPALLGA 133
             +  P+    P    P   A P    PP    P  +  P P     +    +AP  L  
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627

Query: 134 PARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAPKASR 193
           P  + P   P+ P  P L P+A    +  P  L     QA  +P   P   A F+P AS 
Sbjct: 628 PPLQAP---PSPPASPPLSPLATPSPQ-APNALAVHLLQAPFSPPPSPPVQAPFSPPAS- 682

Query: 194 DQQVTDSTTICQRGLIEETGPARQI--SDLCEVSQGVGAFRAGGCPSSLASSREQTHSPH 251
              V+ S T   +       P  Q+  S          A      P  LA+   Q     
Sbjct: 683 -PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ----- 736

Query: 252 LYPSPSSSSPSSWEAPPANSVTP 274
           + PSP +S P S  A P   V P
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPP 759



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 70/290 (24%), Positives = 91/290 (31%), Gaps = 31/290 (10%)

Query: 11  GKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAP------- 63
           G+   P   + P P    G      RP  P   K      + T A G  T AP       
Sbjct: 100 GERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPKRSALSA 158

Query: 64  -SPRDPGLHTPPC-SPRRGRRGRP--TQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFR 119
            + RD    TP   SP   RR R   T+   P P P A+P      P         H   
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 120 CSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPV---AKRRARPVPPGLPGAPKQAAL- 175
               + R     G   +RP +   +    P   P       R  P  P  P  PK   L 
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 176 -------TPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGV 228
                  TP R+   P A  P +S        +    R +      A  +      S  +
Sbjct: 279 ALRPPQVTPPRKDAAP-ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337

Query: 229 GAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRP 278
                   PS  A    QT      PSP ++ PS  +APP+ +  P   P
Sbjct: 338 ATPLPLAPPSPSAPPSLQT-----LPSPPATPPS--QAPPSMTTPPMQAP 380



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 7/65 (10%)

Query: 124 SKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPK--QAALTPGRRP 181
           +KR  A  GA AR P A  P       L P      RP PP  P A +   AA   GR+P
Sbjct: 3   NKRDKAKAGAAARTPAARAPG-----LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP 57

Query: 182 LTPAA 186
           L   A
Sbjct: 58  LAERA 62


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 77/282 (27%), Positives = 105/282 (37%), Gaps = 39/282 (13%)

Query: 15  KPQDQSPPS------PQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDP 68
           KPQ   PP       PQ D+     R  P  P+   PP  P+ G +  GP      P+ P
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG--PP--PQGGNQPQGPPPPPGKPQGP 204

Query: 69  ---GLHTPPCSPRRGR-RGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGS 124
              G + P   P  G+ +G P Q    +    + P     PPP G  QP+  G     G 
Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ--GPPPPPGK 262

Query: 125 KRAPALLGA--PARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLP-GAPKQAALTPGRRP 181
            + P   G   P   PP   P +P+ P  Q  +K R+   PPG P G P Q    P   P
Sbjct: 263 PQGPPPQGGNKPQGPPP---PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319

Query: 182 LTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLA 241
             P    P+    Q           G  +  GP           QG    R+   P    
Sbjct: 320 PPPGK--PQGPPPQ-----------GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366

Query: 242 SS--REQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIP 281
               +++ ++P   P P+  +P   +APPA    P+G P  P
Sbjct: 367 QGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ--PQGPPRPP 406



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 51/173 (29%), Positives = 69/173 (39%), Gaps = 24/173 (13%)

Query: 19  QSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPR 78
           Q PP P +  G  P+ D+   PRS  PP  P+      G Q   P P       PP  P+
Sbjct: 90  QGPPPPGKPQGPPPQGDKSRSPRS--PPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQ 145

Query: 79  RGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPARRP 138
            G + +        P P  +P G   PPP G+ + R    R   G  + P   G    + 
Sbjct: 146 GGNKPQ-------GPPPPGKPQG---PPPQGDNKSR--SSRSPPGKPQGPPPQGGNQPQG 193

Query: 139 PAHIPAQPRWPRLQPVAKRRARPVPPGLPGAP-------KQAALTPGRRPLTP 184
           P   P +P+ P  Q   K +  P PPG P  P        Q+A +P  +P  P
Sbjct: 194 PPPPPGKPQGPPPQGGNKPQG-PPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 49/173 (28%), Positives = 67/173 (38%), Gaps = 26/173 (15%)

Query: 17  QDQSPP----SPQRDSGLTPER-DRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLH 71
           Q++SP     +PQ   G  P+  ++P  P S  PP  P+      G Q   P P      
Sbjct: 25  QEESPSLIAGNPQ---GAPPQGGNKPQGPPS--PPGKPQGPPPQGGNQPQGPPPPPGKPQ 79

Query: 72  TPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALL 131
            PP  P+ G + +        P P  +P G   PPP G+K   P   R   G  + P   
Sbjct: 80  GPP--PQGGNKPQ-------GPPPPGKPQG---PPPQGDKSRSP---RSPPGKPQGPPPQ 124

Query: 132 GAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTP 184
           G    + P   P +P+ P  Q   K +  P PPG P  P        R   +P
Sbjct: 125 GGNQPQGPPPPPGKPQGPPPQGGNKPQG-PPPPGKPQGPPPQGDNKSRSSRSP 176



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 21/152 (13%)

Query: 19  QSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPR 78
           Q PP P +  G  P+        S  PP  P+      G Q   P P       PP  P+
Sbjct: 275 QGPPPPGKPQGPPPQGGSKS-RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQ 331

Query: 79  RGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQP-------RPHGFRCSHGS--KRAPA 129
            G + +        P P  +P G  PPP  G K         +P G     G+  +  P 
Sbjct: 332 GGNKPQ-------GPPPPGKPQG--PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382

Query: 130 LLGAPARRPPAHIPAQPRWPRLQPVAKRRARP 161
             G   ++P A    QP+ P   P   R +RP
Sbjct: 383 PAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 35/119 (29%), Positives = 42/119 (35%), Gaps = 25/119 (21%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGP----QTSAPSPRDPGL 70
           KPQ   P    +  G  P   +P  P        P+ G K  GP    +   P P+    
Sbjct: 303 KPQGPPPQGGNQPQGPPPPPGKPQGP-------PPQGGNKPQGPPPPGKPQGPPPQGGSK 355

Query: 71  HTPPCSPRRGRRGRPTQE-------VCPAPG----PCAQPAGT---CPPPPTGEKQPRP 115
                SP    +G P QE         PA G    P A PAG     P PP G +  RP
Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 60/202 (29%), Positives = 74/202 (36%), Gaps = 33/202 (16%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPC 75
            PQ  S P P +     P+      P +  PP+ P +   A GP    P P+   L  P  
Sbjct: 1285 PQQPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGP---VPGPQHYTLGRPGR 1341

Query: 76   SPRRGRRGRPTQEVCPAPGPCAQPA------GTCPPPPTGEKQPRPHGFRCSHGSKRAPA 129
            +PRRG  G P Q       P  QP          P  P   KQ   H F  SH  +  PA
Sbjct: 1342 APRRGAGGHP-QFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKH-FIFSHHPQMMPA 1399

Query: 130  --LLGAPARRPP-----------------AHIPAQPRWPRLQPVAKRRAR-PVPPGLPGA 169
                G P  RPP                 + IP  P +P L P +      P+PP  P  
Sbjct: 1400 AGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHG 1459

Query: 170  PKQAALTPGRRPLTPAAFAPKA 191
            P  A+  PG     P +  PKA
Sbjct: 1460 PLHASGPPG--TANPPSANPKA 1479



 Score = 35.8 bits (81), Expect = 0.054
 Identities = 33/113 (29%), Positives = 39/113 (34%), Gaps = 12/113 (10%)

Query: 68   PGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRA 127
            PG   PP  P +    +P+    P   P     G+ PPPP       PH    +HG    
Sbjct: 1275 PGPAPPPYLPPQ----QPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPG 1330

Query: 128  PA--LLGAPARRPPAHIPAQP------RWPRLQPVAKRRARPVPPGLPGAPKQ 172
            P    LG P R P       P      R P  QP +        P  P A KQ
Sbjct: 1331 PQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQ 1383



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 21/64 (32%), Positives = 22/64 (34%), Gaps = 7/64 (10%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPC 75
            P    PP P       P    P  P S  PP SP     ASGP    P   +P    P  
Sbjct: 1427 PHSPIPPHPSYPPLPPPS---PHTPHSPLPPTSPHGPLHASGP----PGTANPPSANPKA 1479

Query: 76   SPRR 79
             P R
Sbjct: 1480 KPSR 1483


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 19/182 (10%)

Query: 20  SPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRR 79
           +P +P+  +  TP++  P  P+    P +P++ T  + P+  AP+ ++P   TP      
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPTPTT-PKEPAPTTKEPAPTTP------ 345

Query: 80  GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQPRPHGFR--CSHGSKRAPALLGAPA 135
            +   PT    PAP    +PA T P  P PT  K+P P   +      +K AP     PA
Sbjct: 346 -KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 404

Query: 136 RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPGRR--PLTPAAFAPKA 191
                  P  P+ P   P   +   P  P    P  PK+ A T  +   P TP   AP  
Sbjct: 405 PTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462

Query: 192 SR 193
           ++
Sbjct: 463 TK 464



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 79/313 (25%), Positives = 120/313 (38%), Gaps = 32/313 (10%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAP-SPRD 67
           P+  +P +P++ +  TPE+  P  P    P       P +PE+    + P+ +AP +P++
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT-PKAAAPNTPKE 545

Query: 68  PGLHTP-PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP-----PPPTGEKQPRPHGFRCS 121
           P   TP   +P   +   PT     AP     P GT P     P PT  K+P P     +
Sbjct: 546 PAPTTPKEPAPTTPKEPAPTTPKETAP---TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602

Query: 122 HGSKRAPALLGAPA-RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPG 178
              +        PA   P    P  P+ P   P   +   P  P    P   K+ A T  
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPAPTTP 660

Query: 179 RRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCP- 237
           ++P  P   AP  ++    T S         +ET P           +          P 
Sbjct: 661 KKP-APKELAPTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718

Query: 238 -SSLASSREQTHSP-HLYPSPSSSSP--SSWEAPPANSVTPRGRPGIPAHKLGASSAVCQ 293
            +S  S+   T  P  ++ SP  S+P  S+   P A   +P+  PG+P  K  A++    
Sbjct: 719 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK-EPGVPTTKTPAATKPEM 777

Query: 294 EATYKSLWLTERE 306
             T K    TER+
Sbjct: 778 TTTAKDK-TTERD 789



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 74/318 (23%), Positives = 106/318 (33%), Gaps = 61/318 (19%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-PLSPEKGTKASGPQT-------------- 60
           P++ +P +P+  +  TP+   P   +S    P  P   T  S P T              
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 272

Query: 61  ---SAPSP---RDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQ 112
                P+P   ++P   T   +P   +   PT    PAP    +PA T P  P PT  K+
Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 332

Query: 113 PRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
           P                   AP  + PA  P  P+ P   P A ++  P  P    P  P
Sbjct: 333 P-------------------APTTKEPA--PTTPKEP--APTAPKKPAPTTPKEPAPTTP 369

Query: 171 KQAALTPGRR--PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGV 228
           K+ A T  +   P TP   AP  ++    T             T P        E S   
Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-------EPSPTT 422

Query: 229 GAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGAS 288
               A   P   A +  +  +P     P+ ++P      PA + T +  P  P      +
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTT 478

Query: 289 SAVCQEATYKSLWLTERE 306
                  T K L  T  E
Sbjct: 479 PKETAPTTPKKLTPTTPE 496



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 54/201 (26%), Positives = 78/201 (38%), Gaps = 34/201 (16%)

Query: 15  KPQDQSP--PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAP-SPRDPGLH 71
           KP   +P  P+P      TP   +   P + +P  +  K    + P+  AP +P++P   
Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367

Query: 72  TP------------PCSPRR----GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQP 113
           TP            P +P+       +  PT    PAP    + A T P  P PT  K+P
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEP 426

Query: 114 RPHGFRCSHGSKRAPALLGAPARRPPAH-IPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
            P     +   + AP     PA   P    P  P+ P   P   ++  P  P    P  P
Sbjct: 427 AP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPKEPAPTTP 479

Query: 171 KQAALTPGRR--PLTPAAFAP 189
           K+ A T  ++  P TP   AP
Sbjct: 480 KETAPTTPKKLTPTTPEKLAP 500



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 55/276 (19%), Positives = 96/276 (34%), Gaps = 33/276 (11%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAPSPRDP 68
           P+  +P +P+  +  TP+   P  P+   P       P +P+K        T+   P   
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679

Query: 69  GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP---PPPTGEKQPRPHGFRCSHGSK 125
               P  +P   +   PT    PAP    +PA T P   PP T E          +  + 
Sbjct: 680 TSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS--------TPTTT 729

Query: 126 RAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPA 185
           + P  +          + A+P    L+        P  PG+P     AA  P    +T  
Sbjct: 730 KEPTTIHKSPDESTPELSAEPTPKALE------NSPKEPGVPTTKTPAATKP---EMTTT 780

Query: 186 AFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEV----SQGVGAFRAGGCPSSLA 241
           A      RD + T  TT     + +ET    + +   ++    +Q          P  + 
Sbjct: 781 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 840

Query: 242 SSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGR 277
           + +  T +P +  +  + + +     P  +  P+ R
Sbjct: 841 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR 876


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 19/182 (10%)

Query: 20  SPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRR 79
           +P +P+  +  TP++  P  P+    P +P++ T  + P+  AP+ ++P   TP      
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPTPTT-PKEPAPTTKEPAPTTP------ 386

Query: 80  GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQPRPHGFR--CSHGSKRAPALLGAPA 135
            +   PT    PAP    +PA T P  P PT  K+P P   +      +K AP     PA
Sbjct: 387 -KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 445

Query: 136 RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPGRR--PLTPAAFAPKA 191
                  P  P+ P   P   +   P  P    P  PK+ A T  +   P TP   AP  
Sbjct: 446 PTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503

Query: 192 SR 193
           ++
Sbjct: 504 TK 505



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 79/313 (25%), Positives = 120/313 (38%), Gaps = 32/313 (10%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAP-SPRD 67
           P+  +P +P++ +  TPE+  P  P    P       P +PE+    + P+ +AP +P++
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT-PKAAAPNTPKE 586

Query: 68  PGLHTP-PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP-----PPPTGEKQPRPHGFRCS 121
           P   TP   +P   +   PT     AP     P GT P     P PT  K+P P     +
Sbjct: 587 PAPTTPKEPAPTTPKEPAPTTPKETAP---TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643

Query: 122 HGSKRAPALLGAPA-RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPG 178
              +        PA   P    P  P+ P   P   +   P  P    P   K+ A T  
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPAPTTP 701

Query: 179 RRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCP- 237
           ++P  P   AP  ++    T S         +ET P           +          P 
Sbjct: 702 KKP-APKELAPTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759

Query: 238 -SSLASSREQTHSP-HLYPSPSSSSP--SSWEAPPANSVTPRGRPGIPAHKLGASSAVCQ 293
            +S  S+   T  P  ++ SP  S+P  S+   P A   +P+  PG+P  K  A++    
Sbjct: 760 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK-EPGVPTTKTPAATKPEM 818

Query: 294 EATYKSLWLTERE 306
             T K    TER+
Sbjct: 819 TTTAKDK-TTERD 830



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 74/318 (23%), Positives = 106/318 (33%), Gaps = 61/318 (19%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-PLSPEKGTKASGPQT-------------- 60
           P++ +P +P+  +  TP+   P   +S    P  P   T  S P T              
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 313

Query: 61  ---SAPSP---RDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQ 112
                P+P   ++P   T   +P   +   PT    PAP    +PA T P  P PT  K+
Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 373

Query: 113 PRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
           P                   AP  + PA  P  P+ P   P A ++  P  P    P  P
Sbjct: 374 P-------------------APTTKEPA--PTTPKEP--APTAPKKPAPTTPKEPAPTTP 410

Query: 171 KQAALTPGRR--PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGV 228
           K+ A T  +   P TP   AP  ++    T             T P        E S   
Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-------EPSPTT 463

Query: 229 GAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGAS 288
               A   P   A +  +  +P     P+ ++P      PA + T +  P  P      +
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTT 519

Query: 289 SAVCQEATYKSLWLTERE 306
                  T K L  T  E
Sbjct: 520 PKETAPTTPKKLTPTTPE 537



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 54/201 (26%), Positives = 78/201 (38%), Gaps = 34/201 (16%)

Query: 15  KPQDQSP--PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAP-SPRDPGLH 71
           KP   +P  P+P      TP   +   P + +P  +  K    + P+  AP +P++P   
Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408

Query: 72  TP------------PCSPRR----GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQP 113
           TP            P +P+       +  PT    PAP    + A T P  P PT  K+P
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEP 467

Query: 114 RPHGFRCSHGSKRAPALLGAPARRPPAH-IPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
            P     +   + AP     PA   P    P  P+ P   P   ++  P  P    P  P
Sbjct: 468 AP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPKEPAPTTP 520

Query: 171 KQAALTPGRR--PLTPAAFAP 189
           K+ A T  ++  P TP   AP
Sbjct: 521 KETAPTTPKKLTPTTPEKLAP 541



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 55/276 (19%), Positives = 96/276 (34%), Gaps = 33/276 (11%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAPSPRDP 68
           P+  +P +P+  +  TP+   P  P+   P       P +P+K        T+   P   
Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 720

Query: 69  GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP---PPPTGEKQPRPHGFRCSHGSK 125
               P  +P   +   PT    PAP    +PA T P   PP T E          +  + 
Sbjct: 721 TSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS--------TPTTT 770

Query: 126 RAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPA 185
           + P  +          + A+P    L+        P  PG+P     AA  P    +T  
Sbjct: 771 KEPTTIHKSPDESTPELSAEPTPKALE------NSPKEPGVPTTKTPAATKP---EMTTT 821

Query: 186 AFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEV----SQGVGAFRAGGCPSSLA 241
           A      RD + T  TT     + +ET    + +   ++    +Q          P  + 
Sbjct: 822 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 881

Query: 242 SSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGR 277
           + +  T +P +  +  + + +     P  +  P+ R
Sbjct: 882 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR 917


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 19/182 (10%)

Query: 20  SPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRR 79
           +P +P+  +  TP++  P  P+    P +P++ T  + P+  AP+ ++P   TP      
Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPTPTT-PKEPAPTTKEPAPTTP------ 438

Query: 80  GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQPRPHGFR--CSHGSKRAPALLGAPA 135
            +   PT    PAP    +PA T P  P PT  K+P P   +      +K AP     PA
Sbjct: 439 -KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 497

Query: 136 RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPGRR--PLTPAAFAPKA 191
                  P  P+ P   P   +   P  P    P  PK+ A T  +   P TP   AP  
Sbjct: 498 PTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555

Query: 192 SR 193
           ++
Sbjct: 556 TK 557



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 79/313 (25%), Positives = 120/313 (38%), Gaps = 32/313 (10%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAP-SPRD 67
           P+  +P +P++ +  TPE+  P  P    P       P +PE+    + P+ +AP +P++
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT-PKAAAPNTPKE 638

Query: 68  PGLHTP-PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP-----PPPTGEKQPRPHGFRCS 121
           P   TP   +P   +   PT     AP     P GT P     P PT  K+P P     +
Sbjct: 639 PAPTTPKEPAPTTPKEPAPTTPKETAP---TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695

Query: 122 HGSKRAPALLGAPA-RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPG 178
              +        PA   P    P  P+ P   P   +   P  P    P   K+ A T  
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPAPTTP 753

Query: 179 RRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCP- 237
           ++P  P   AP  ++    T S         +ET P           +          P 
Sbjct: 754 KKP-APKELAPTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811

Query: 238 -SSLASSREQTHSP-HLYPSPSSSSP--SSWEAPPANSVTPRGRPGIPAHKLGASSAVCQ 293
            +S  S+   T  P  ++ SP  S+P  S+   P A   +P+  PG+P  K  A++    
Sbjct: 812 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK-EPGVPTTKTPAATKPEM 870

Query: 294 EATYKSLWLTERE 306
             T K    TER+
Sbjct: 871 TTTAKDK-TTERD 882



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 74/318 (23%), Positives = 106/318 (33%), Gaps = 61/318 (19%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-PLSPEKGTKASGPQT-------------- 60
           P++ +P +P+  +  TP+   P   +S    P  P   T  S P T              
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 365

Query: 61  ---SAPSP---RDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQ 112
                P+P   ++P   T   +P   +   PT    PAP    +PA T P  P PT  K+
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 425

Query: 113 PRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
           P                   AP  + PA  P  P+ P   P A ++  P  P    P  P
Sbjct: 426 P-------------------APTTKEPA--PTTPKEP--APTAPKKPAPTTPKEPAPTTP 462

Query: 171 KQAALTPGRR--PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGV 228
           K+ A T  +   P TP   AP  ++    T             T P        E S   
Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-------EPSPTT 515

Query: 229 GAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGAS 288
               A   P   A +  +  +P     P+ ++P      PA + T +  P  P      +
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTT 571

Query: 289 SAVCQEATYKSLWLTERE 306
                  T K L  T  E
Sbjct: 572 PKETAPTTPKKLTPTTPE 589



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 54/201 (26%), Positives = 78/201 (38%), Gaps = 34/201 (16%)

Query: 15  KPQDQSP--PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAP-SPRDPGLH 71
           KP   +P  P+P      TP   +   P + +P  +  K    + P+  AP +P++P   
Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460

Query: 72  TP------------PCSPRR----GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQP 113
           TP            P +P+       +  PT    PAP    + A T P  P PT  K+P
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEP 519

Query: 114 RPHGFRCSHGSKRAPALLGAPARRPPAH-IPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
            P     +   + AP     PA   P    P  P+ P   P   ++  P  P    P  P
Sbjct: 520 AP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPKEPAPTTP 572

Query: 171 KQAALTPGRR--PLTPAAFAP 189
           K+ A T  ++  P TP   AP
Sbjct: 573 KETAPTTPKKLTPTTPEKLAP 593



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 55/276 (19%), Positives = 96/276 (34%), Gaps = 33/276 (11%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAPSPRDP 68
           P+  +P +P+  +  TP+   P  P+   P       P +P+K        T+   P   
Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 772

Query: 69  GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP---PPPTGEKQPRPHGFRCSHGSK 125
               P  +P   +   PT    PAP    +PA T P   PP T E          +  + 
Sbjct: 773 TSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS--------TPTTT 822

Query: 126 RAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPA 185
           + P  +          + A+P    L+        P  PG+P     AA  P    +T  
Sbjct: 823 KEPTTIHKSPDESTPELSAEPTPKALE------NSPKEPGVPTTKTPAATKP---EMTTT 873

Query: 186 AFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEV----SQGVGAFRAGGCPSSLA 241
           A      RD + T  TT     + +ET    + +   ++    +Q          P  + 
Sbjct: 874 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 933

Query: 242 SSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGR 277
           + +  T +P +  +  + + +     P  +  P+ R
Sbjct: 934 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR 969


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 19/182 (10%)

Query: 20  SPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRR 79
           +P +P+  +  TP++  P  P+    P +P++ T  + P+  AP+ ++P   TP      
Sbjct: 428 APTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPTPTT-PKEPAPTTKEPAPTTP------ 479

Query: 80  GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQPRPHGFR--CSHGSKRAPALLGAPA 135
            +   PT    PAP    +PA T P  P PT  K+P P   +      +K AP     PA
Sbjct: 480 -KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 538

Query: 136 RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPGRR--PLTPAAFAPKA 191
                  P  P+ P   P   +   P  P    P  PK+ A T  +   P TP   AP  
Sbjct: 539 PTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596

Query: 192 SR 193
           ++
Sbjct: 597 TK 598



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 79/313 (25%), Positives = 120/313 (38%), Gaps = 32/313 (10%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAP-SPRD 67
           P+  +P +P++ +  TPE+  P  P    P       P +PE+    + P+ +AP +P++
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT-PKAAAPNTPKE 679

Query: 68  PGLHTP-PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP-----PPPTGEKQPRPHGFRCS 121
           P   TP   +P   +   PT     AP     P GT P     P PT  K+P P     +
Sbjct: 680 PAPTTPKEPAPTTPKEPAPTTPKETAP---TTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736

Query: 122 HGSKRAPALLGAPA-RRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQAALTPG 178
              +        PA   P    P  P+ P   P   +   P  P    P   K+ A T  
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPAPTTP 794

Query: 179 RRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCP- 237
           ++P  P   AP  ++    T S         +ET P           +          P 
Sbjct: 795 KKP-APKELAPTTTKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852

Query: 238 -SSLASSREQTHSP-HLYPSPSSSSP--SSWEAPPANSVTPRGRPGIPAHKLGASSAVCQ 293
            +S  S+   T  P  ++ SP  S+P  S+   P A   +P+  PG+P  K  A++    
Sbjct: 853 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK-EPGVPTTKTPAATKPEM 911

Query: 294 EATYKSLWLTERE 306
             T K    TER+
Sbjct: 912 TTTAKDK-TTERD 923



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 74/318 (23%), Positives = 106/318 (33%), Gaps = 61/318 (19%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-PLSPEKGTKASGPQT-------------- 60
           P++ +P +P+  +  TP+   P   +S    P  P   T  S P T              
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 406

Query: 61  ---SAPSP---RDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQ 112
                P+P   ++P   T   +P   +   PT    PAP    +PA T P  P PT  K+
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 466

Query: 113 PRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
           P                   AP  + PA  P  P+ P   P A ++  P  P    P  P
Sbjct: 467 P-------------------APTTKEPA--PTTPKEP--APTAPKKPAPTTPKEPAPTTP 503

Query: 171 KQAALTPGRR--PLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGV 228
           K+ A T  +   P TP   AP  ++    T             T P        E S   
Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-------EPSPTT 556

Query: 229 GAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGAS 288
               A   P   A +  +  +P     P+ ++P      PA + T +  P  P      +
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE----PAPTTTKKPAPTTPKEPAPTT 612

Query: 289 SAVCQEATYKSLWLTERE 306
                  T K L  T  E
Sbjct: 613 PKETAPTTPKKLTPTTPE 630



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 54/201 (26%), Positives = 78/201 (38%), Gaps = 34/201 (16%)

Query: 15  KPQDQSP--PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAP-SPRDPGLH 71
           KP   +P  P+P      TP   +   P + +P  +  K    + P+  AP +P++P   
Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501

Query: 72  TP------------PCSPRR----GRRGRPTQEVCPAPGPCAQPAGTCP--PPPTGEKQP 113
           TP            P +P+       +  PT    PAP    + A T P  P PT  K+P
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP-TTTKSAPTTPKEPSPTTTKEP 560

Query: 114 RPHGFRCSHGSKRAPALLGAPARRPPAH-IPAQPRWPRLQPVAKRRARPVPP--GLPGAP 170
            P     +   + AP     PA   P    P  P+ P   P   ++  P  P    P  P
Sbjct: 561 AP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEP--APTTTKKPAPTTPKEPAPTTP 613

Query: 171 KQAALTPGRR--PLTPAAFAP 189
           K+ A T  ++  P TP   AP
Sbjct: 614 KETAPTTPKKLTPTTPEKLAP 634



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 55/276 (19%), Positives = 96/276 (34%), Gaps = 33/276 (11%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKP-------PLSPEKGTKASGPQTSAPSPRDP 68
            P+  +P +P+  +  TP+   P  P+   P       P +P+K        T+   P   
Sbjct: 754  PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 813

Query: 69   GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCP---PPPTGEKQPRPHGFRCSHGSK 125
                P  +P   +   PT    PAP    +PA T P   PP T E          +  + 
Sbjct: 814  TSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS--------TPTTT 863

Query: 126  RAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPA 185
            + P  +          + A+P    L+        P  PG+P     AA  P    +T  
Sbjct: 864  KEPTTIHKSPDESTPELSAEPTPKALE------NSPKEPGVPTTKTPAATKP---EMTTT 914

Query: 186  AFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEV----SQGVGAFRAGGCPSSLA 241
            A      RD + T  TT     + +ET    + +   ++    +Q          P  + 
Sbjct: 915  AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 974

Query: 242  SSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGR 277
            + +  T +P +  +  + + +     P  +  P+ R
Sbjct: 975  TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR 1010


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 63/242 (26%), Positives = 87/242 (35%), Gaps = 43/242 (17%)

Query: 11  GKNYKPQDQSPPSPQR--------DSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSA 62
           G+    Q   PP+ QR          G  P+R  P  P   +PP   ++     GP   +
Sbjct: 445 GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP--PLQQRPPPQGQQHLSGLGPPAGS 502

Query: 63  P----------SPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQ 112
           P          +P+ P     P +  +GR+ RP      A GP A PA   P  P+ ++Q
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPV-----AGGPGAPPAARPPASPSPQRQ 557

Query: 113 PRPHGF--RCSHGSKRAPALLGAPA----RRPPAHIPAQPRWPRLQ-----------PVA 155
             P     + S      P   GAP     R+ P   P  P  P  Q           P  
Sbjct: 558 AGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPT 617

Query: 156 KRRARPVPPGLPGAPK-QAALTPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGP 214
            ++ RP  PG  G PK Q A  P +    PA  A       Q+  S ++     + E  P
Sbjct: 618 TQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAP 677

Query: 215 AR 216
            R
Sbjct: 678 PR 679



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 64/231 (27%), Positives = 89/231 (38%), Gaps = 43/231 (18%)

Query: 4   ERILNLYGKNYKPQDQSPPSPQRDS-GLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSA 62
           E ++N   +    Q Q   SP R S G TP       P +   PL  +   + +GP    
Sbjct: 408 ELVVNKMAQALPRQRQRDASPGRGSHGQTPS------PGAL--PLGRQTSQQPAGPPAQQ 459

Query: 63  PSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGP-----CAQPAGT-----CPPPPTGEKQ 112
             P   G   P   P+R  +G P Q+  P  G         PAG+      P P +  +Q
Sbjct: 460 RPPPQGGPPQPGPGPQR--QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517

Query: 113 PRPHGFRCSHG-SKRAPALLGAPARRPPAHIPAQPRWPRLQ---PVAKRR---ARPVPPG 165
           P       + G  +++  + G P   P A  PA P  P+ Q   P A R+   + P PP 
Sbjct: 518 PASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS-PQRQAGPPQATRQTSVSGPAPPK 576

Query: 166 LPGAPK--QAALTPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGP 214
             GAP   Q    P ++P  PA    +AS            Q G +  TGP
Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQAS------------QAGPVPRTGP 615


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 74/295 (25%), Positives = 98/295 (33%), Gaps = 64/295 (21%)

Query: 22  PSPQRDSGLT------PERDRPDWP--RSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTP 73
           PSPQ  + L       P    P  P    F PP SP     A+ P  + PS   P L  P
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482

Query: 74  PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGA 133
           P  P       P       P P A P    PP    +  P+      +  +   P L   
Sbjct: 483 PSPP-----ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ------APPALATPPLQAL 531

Query: 134 PARRPPAHIPAQPRW---------------PRLQPVAKRRARPVPPGLPGAPKQAALTPG 178
           P+  PPA  P Q  +               P+  PV       VPP  P +P    L   
Sbjct: 532 PS--PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP---TLQAP 586

Query: 179 RRPLTPA------------AFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQ 226
           RRP TP             A AP        + S+T+    L    G +   +   E  +
Sbjct: 587 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL---AGHSSSATSTPEELR 643

Query: 227 GVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIP 281
           G  +   GG  +S     E           ++  P++W   PA  +  RG PG P
Sbjct: 644 GYDSGPEGGAAASPPPDAEL----------AACHPAAWSRGPAPPLAFRGAPGAP 688



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 85/318 (26%), Positives = 111/318 (34%), Gaps = 53/318 (16%)

Query: 11  GKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAP------- 63
           G+   P   + P P    G      RP  P   K      + T A G  T AP       
Sbjct: 100 GERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPKRSALSA 158

Query: 64  -SPRDPGLHTPPC-SPRRGRRGRP--TQEVCPAPGPCAQPA----------------GTC 103
            + RD    TP   SP   RR R   T+   P P P A+P                  T 
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 104 PPPPTGEKQPRPHG---------FRCSHGSKRAPALLGAPAR---RPPAHIPAQPRWPRL 151
            P P   ++P   G            S     +PA  G  AR   R PAH P+QP+   L
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGL 277

Query: 152 QPVAKRRARPVPPGLPGAPKQAAL--TPGRRPLTPAAFAPKASRDQQVT--DSTTICQRG 207
           Q  A R  +  PP    AP    L  +P   P   AA   +A      T   S+  CQ  
Sbjct: 278 Q--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335

Query: 208 L-IEETGPARQISDLCEVSQGVGAFRAGGCPSSLAS-SREQTHS--PHLYPSPSSSSPSS 263
             +    P+       +      A       +SL S + + THS  P    SP ++ P  
Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP- 394

Query: 264 WEAPPANSVTPRGRPGIP 281
            +APPA ++ P   P  P
Sbjct: 395 -QAPPALALPPLQAPPSP 411



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 70/243 (28%), Positives = 90/243 (37%), Gaps = 53/243 (21%)

Query: 49  PEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQP---AGTCPP 105
           PE   +A   +++  S R+P    PP S R G R  P +    +PGP + P   +GT  P
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASR-PPASGR-GERAPPAKNT--SPGPVSSPGRASGTTRP 126

Query: 106 PPTGEKQPRPHGFRCSHGSKRAPA----LLGAPARRPPAH-IPAQPRWPRLQPVAKRRAR 160
            P G+K  R          K   A     L A ARR  +   P  P      P   RR+R
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-----SPAMARRSR 181

Query: 161 PVPPGLPGAPKQAALTPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISD 220
                + G P+ A   P  RP  P    P+ S       STT        E  PA +   
Sbjct: 182 AAGTEV-GLPRPA---PSARPRPPTE-GPRKSVSSASEHSTT--------EPSPAARRRP 228

Query: 221 LCEVSQGVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGI 280
               S G G  R         +SR  + S     SP+ S PS+           RG P  
Sbjct: 229 ----SAGGGLQRP--------ASRSLSSSATPLSSPARSGPSA-----------RGTPRA 265

Query: 281 PAH 283
           PAH
Sbjct: 266 PAH 268



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 7/65 (10%)

Query: 124 SKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPK--QAALTPGRRP 181
           +KR  A  GA AR P A  P       L P      RP PP  P A +   AA   GR+P
Sbjct: 3   NKRDKAKAGAAARTPAARAPG-----LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP 57

Query: 182 LTPAA 186
           L   A
Sbjct: 58  LAERA 62


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 74/295 (25%), Positives = 98/295 (33%), Gaps = 64/295 (21%)

Query: 22  PSPQRDSGLT------PERDRPDWP--RSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTP 73
           PSPQ  + L       P    P  P    F PP SP     A+ P  + PS   P L  P
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443

Query: 74  PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGA 133
           P  P       P       P P A P    PP    +  P+      +  +   P L   
Sbjct: 444 PSPP-----ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ------APPALATPPLQAL 492

Query: 134 PARRPPAHIPAQPRW---------------PRLQPVAKRRARPVPPGLPGAPKQAALTPG 178
           P+  PPA  P Q  +               P+  PV       VPP  P +P    L   
Sbjct: 493 PS--PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP---TLQAP 547

Query: 179 RRPLTPA------------AFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQ 226
           RRP TP             A AP        + S+T+    L    G +   +   E  +
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL---AGHSSSATSTPEELR 604

Query: 227 GVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIP 281
           G  +   GG  +S     E           ++  P++W   PA  +  RG PG P
Sbjct: 605 GYDSGPEGGAAASPPPDAEL----------AACHPAAWSRGPAPPLAFRGAPGAP 649



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 84/322 (26%), Positives = 110/322 (34%), Gaps = 58/322 (18%)

Query: 11  GKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAP------- 63
           G+   P   + P P    G      RP  P   K      + T A G  T AP       
Sbjct: 91  GERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPKRSALSA 149

Query: 64  -SPRDPGLHTPPC-SPRRGRRGRP--TQEVCPAPGPCAQPA----------------GTC 103
            + RD    TP   SP   RR R   T+   P P P A+P                  T 
Sbjct: 150 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 209

Query: 104 PPPPTGEKQPRPHG---------FRCSHGSKRAPALLGAPAR---RPPAHIPAQPRWPRL 151
            P P   ++P   G            S     +PA  G  AR   R PAH P+QP+   L
Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGL 268

Query: 152 QPVAKRRARPVPPGLPGAPKQAAL--TPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLI 209
           Q  A R  +  PP    AP    L  +P   P   A  +P A    Q   S         
Sbjct: 269 Q--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP-------- 318

Query: 210 EETGPARQISDL-CEVSQGVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPP 268
             T P++  + L     Q   +F      S LA+   Q   P L   P  + PS   +PP
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA-PPALALPPLQAPPSPPASPP 377

Query: 269 ANSV---TPRGRPGIPAHKLGA 287
            + +   +P+    +  H L A
Sbjct: 378 LSPLATPSPQAPNALAVHLLQA 399



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 71/278 (25%), Positives = 95/278 (34%), Gaps = 46/278 (16%)

Query: 61  SAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQP---AGTCPPPPTGEKQPRPHG 117
           SAP         PP S R G R  P +    +PGP + P   +GT  P P G+K  R   
Sbjct: 73  SAPRAGPTRTSRPPASGR-GERAPPAKNT--SPGPVSSPGRASGTTRPGPLGQKGLRISA 129

Query: 118 FRCSHGSKRAPA----LLGAPARR------PPAHIPAQPRWPRLQ------PVAKRRARP 161
                  K   A     L A ARR      P    PA  R  R        P     ARP
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189

Query: 162 VPP------GLPGAPKQAALTPG----RRPLTPAAFAPKASRD--QQVTDSTTICQRGLI 209
            PP       +  A + +   P     RRP         ASR      T  ++  + G  
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 249

Query: 210 EETGPARQISDLCEVSQGVGAFRAGGCPSSLASSREQTHSPHLYP-------SPSSSSPS 262
               P           +G+ A R    P  +   R+   +P L P       +PS S+P 
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALR----PPQVTPPRKDA-APALGPLSSSPLATPSPSAPP 304

Query: 263 SWEAPPANSVTPRGRPGIPAHKLGASSAVCQEATYKSL 300
           S  APP+    P      P+    +  +   +AT+  L
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 7/65 (10%)

Query: 124 SKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPK--QAALTPGRRP 181
           +KR  A  GA AR P A  P       L P      RP PP  P A +   AA   GR+P
Sbjct: 3   NKRDKAKAGAAARTPAARAPG-----LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP 57

Query: 182 LTPAA 186
           L   A
Sbjct: 58  LAERA 62



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 62/259 (23%), Positives = 91/259 (35%), Gaps = 42/259 (16%)

Query: 95  PCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPV 154
           P A+  G   P P G  +P P     +  + R     GA  R+P A          + P 
Sbjct: 17  PAARAPGLLTPRPPGSPRPPP---PVTPAALRVLGAAGAVGRKPLAERAGGIGGATI-PE 72

Query: 155 AKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAPKASRDQQVTDSTTICQRGL---IEE 211
           +  RA P     P A  +    P  +  +P   +    R    T    + Q+GL    EE
Sbjct: 73  SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVS-SPGRASGTTRPGPLGQKGLRISAEE 131

Query: 212 T---GPARQISDLCEVSQGVGAFRAG---GCPSSLASSREQT---------HSPHLYPSP 256
           T   G A +      +S G     +G   G PS   + R +           +P   P P
Sbjct: 132 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 191

Query: 257 ----------SSSSPSSWEAPPANSVTPRGRPGI--PAHKLGASSAVCQEATYKSLWLTE 304
                     S+S  S+ E  PA    P    G+  PA +  +SSA    +  +S   + 
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS-GPSA 250

Query: 305 RETPHSLLLCLSPSHALSP 323
           R TP       +P+H   P
Sbjct: 251 RGTPR------APAHPSQP 263


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 54/178 (30%), Positives = 72/178 (40%), Gaps = 23/178 (12%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPP 74
           KP+ + P       G  P+R  P   +   PP  P+ G ++ GP    P P  P    P 
Sbjct: 35  KPEGRRP-----QGGNQPQRPPPPPGKPQGPP--PQGGNQSQGPP---PPPGKPEGRPPQ 84

Query: 75  CSPR-RGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGS-------KR 126
              + +G    P +   P P    Q  GT PPPP   ++P P G   SH         +R
Sbjct: 85  GGNQSQGPPPHPGKPERPPPQGGNQSQGT-PPPPGKPERPPPQGGNQSHRPPPPPGKPER 143

Query: 127 APALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTP 184
            P   G  ++ PP H P +P  P  Q   K R+   PPG P  P Q     G +P  P
Sbjct: 144 PPPQGGNQSQGPPPH-PGKPEGPPPQEGNKSRSARSPPGKPQGPPQ---QEGNKPQGP 197



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 55/192 (28%), Positives = 73/192 (38%), Gaps = 28/192 (14%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPP 74
           +PQ + PP P +  G  P+           PP  PE      G Q+  P P       PP
Sbjct: 46  QPQ-RPPPPPGKPQGPPPQGGNQSQGPP-PPPGKPEGRPPQGGNQSQGPPPHPGKPERPP 103

Query: 75  CSPRRGRRGRPTQEVCPAPGPCAQP-------AGTCPPPPTGEKQPRPHGFRCSHGSKRA 127
             P+ G + + T    P PG   +P       +   PPPP   ++P P G   S G    
Sbjct: 104 --PQGGNQSQGTP---PPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPH 158

Query: 128 PALLGAPARRPPAH---------IPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPG 178
           P   G P   PP            P +P+ P  Q   K +  P PPG P  P  A   P 
Sbjct: 159 P---GKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPP-PPGKPQGPPPAGGNP- 213

Query: 179 RRPLTPAAFAPK 190
           ++P  P A  P+
Sbjct: 214 QQPQAPPAGKPQ 225



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 7/104 (6%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPP 74
           KP+   P    +  G  P   +P+ P    PP    K   A  P      P     + P 
Sbjct: 140 KPERPPPQGGNQSQGPPPHPGKPEGP----PPQEGNKSRSARSPPGKPQGPPQQEGNKPQ 195

Query: 75  CSPRRGRRGRPTQEVCPAPGPCAQPAGT---CPPPPTGEKQPRP 115
             P  G+   P         P A PAG     PPPP G + PRP
Sbjct: 196 GPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRP 239


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 51/178 (28%), Positives = 64/178 (35%), Gaps = 25/178 (14%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDP----GL 70
           KP+ Q P    +  G  P   +P+ P        P+ G ++ GP      P  P    G 
Sbjct: 98  KPEGQPPQGGNQSQGPPPRPGKPEGP-------PPQGGNQSQGPPPRPGKPEGPPPQGGN 150

Query: 71  HTPPCSPRRGR-RGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQ-----PRPHGFRCSHGS 124
            +    PR G+  G P Q    + GP   P     PPP G  Q     PRP       G 
Sbjct: 151 QSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP-------GK 203

Query: 125 KRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLP-GAPKQAALTPGRRP 181
              P   G    + P   P +P  P  Q   K +  P  PG P G P Q    P R P
Sbjct: 204 PEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPP 261



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 56/201 (27%), Positives = 70/201 (34%), Gaps = 38/201 (18%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPP 74
           KP+ + P       G  P+R  P       PP  PE      G Q+  P PR      PP
Sbjct: 35  KPEGRRP-----QGGNQPQRTPP-------PPGKPEGRPPQGGNQSQGPPPRPGKPEGPP 82

Query: 75  CS---------PRRGR-RGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQ-----PRPHGFR 119
                      PR G+  G+P Q    + GP  +P     PPP G  Q     PRP    
Sbjct: 83  PQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP---- 138

Query: 120 CSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLP-GAPKQA---AL 175
              G    P   G    + P   P +P  P  Q   + +  P  PG P G P Q    + 
Sbjct: 139 ---GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQ 195

Query: 176 TPGRRPLTPAAFAPKASRDQQ 196
            P  RP  P    P+     Q
Sbjct: 196 GPPPRPGKPEGPPPQGGNQSQ 216



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 51/192 (26%), Positives = 69/192 (35%), Gaps = 30/192 (15%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWP------RSFKPPLSPEK--------GTKASGPQT 60
           KP+ + P    +  G  P   +P+ P      +S  PP  P K        G ++ GP  
Sbjct: 56  KPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPP 115

Query: 61  SAPSPRDP----GLHTPPCSPRRGR-RGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQ--- 112
               P  P    G  +    PR G+  G P Q    + GP  +P     PPP G  Q   
Sbjct: 116 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG 175

Query: 113 PRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQ 172
           P PH      G    P   G    + P   P +P  P  Q   + +    PP  PG P+ 
Sbjct: 176 PPPHP-----GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG---PPPRPGKPEG 227

Query: 173 AALTPGRRPLTP 184
                G +P  P
Sbjct: 228 PPSQGGNKPQGP 239



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/108 (31%), Positives = 39/108 (36%), Gaps = 10/108 (9%)

Query: 15  KPQDQSPPSPQRDSGLTPERDRPDWPRSF---KPPLSPEKGTKASGP--QTSAPSPRDPG 69
           KP+   P    +  G  P   +P+ P S    KP   P    K  GP  Q      R P 
Sbjct: 203 KPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPP 262

Query: 70  LHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHG 117
              P   P  G  G P Q   P P P  +P G  PPP  G     P G
Sbjct: 263 PGRPQGPPPPG--GNPQQ---PLPPPAGKPQGPPPPPQGGRPHRPPQG 305



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/157 (27%), Positives = 52/157 (33%), Gaps = 34/157 (21%)

Query: 21  PPSPQRDSGLTPE---RDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSP 77
           PP P +  G  P+   + +   PR  KP   P +G    G Q+  P PR      PP   
Sbjct: 177 PPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG----GNQSQGPPPRPGKPEGPPSQG 232

Query: 78  RRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPARR 137
               +G P     P   P  +      PPP G  Q  P                      
Sbjct: 233 GNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPP---------------------- 270

Query: 138 PPAHIPAQPRWPRLQPVAKRRARPVPP--GLPGAPKQ 172
           PP   P QP  P   P  K +  P PP  G P  P Q
Sbjct: 271 PPGGNPQQPLPP---PAGKPQGPPPPPQGGRPHRPPQ 304


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 64/242 (26%), Positives = 81/242 (33%), Gaps = 46/242 (19%)

Query: 25  QRDSGLTPERDRPDWPR----------SFKPPLSPEKGTKASGPQTSAPSPRDP------ 68
           +R  G  PER R +  +          S+K  +S     +   P+  A  P  P      
Sbjct: 59  RRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGA 118

Query: 69  ----GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGS 124
                   PP +P       P     PA  P A  A    PP  G  QP P   R +  +
Sbjct: 119 PAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLA 178

Query: 125 KRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTP 184
              P    APA  P    PA PR      VA R     PP  P AP Q    P  +P  P
Sbjct: 179 APPP----APAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234

Query: 185 AAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLASSR 244
                               + G +   G AR +S L EV + +G   +GG    L   R
Sbjct: 235 P-------------------EGGAVRAGGAARPVS-LREVVRYLGG--SGGAGGRLTRGR 272

Query: 245 EQ 246
            Q
Sbjct: 273 VQ 274



 Score = 32.3 bits (72), Expect = 0.60
 Identities = 31/113 (27%), Positives = 36/113 (31%), Gaps = 27/113 (23%)

Query: 19  QSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPR 78
           Q  P  QR + L      P  P +  PP  P    +A  P  +A  P  P          
Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPR---RAPPPAVAAREPPLP---------- 212

Query: 79  RGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALL 131
                       P P P A P    PPPP  + QP P G     G    P  L
Sbjct: 213 ------------PPPQPPAPPQQQQPPPP--QPQPPPEGGAVRAGGAARPVSL 251


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 60/218 (27%), Positives = 80/218 (36%), Gaps = 46/218 (21%)

Query: 11  GKNYKPQDQSPPSPQR--------DSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSA 62
           G+    Q   PP+ QR          G  P+R  P  P   +PP   ++     GP   +
Sbjct: 445 GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP--PLQQRPPPQGQQHLSGLGPPAGS 502

Query: 63  P----------SPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQ 112
           P          +P+ P     P +  +GR+ RP      A GP A PA   P  P+ ++Q
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPV-----AGGPGAPPAARPPASPSPQRQ 557

Query: 113 PRPHGF--RCSHGSKRAPALLGAPA----RRPPAHIPAQPRWPRLQ-----------PVA 155
             P     + S      P   GAP     R+ P   P  P  P  Q           P  
Sbjct: 558 AGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPT 617

Query: 156 KRRARPVPPGLPGAPK-QAALTPGR---RPLTPAAFAP 189
            ++ RP  PG  G PK Q A  P +    P T AA  P
Sbjct: 618 TQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGP 655



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 46/161 (28%), Positives = 61/161 (37%), Gaps = 23/161 (14%)

Query: 20  SPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQ----TSAPSPRDPGLHTPPC 75
           +PP+  +     P    P  P + +PP SP    +A  PQ    TS   P  P     P 
Sbjct: 523 APPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582

Query: 76  SPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGE---KQPRPHGFRCSHGSKRAPALLG 132
             ++ R+G P +   PA GP  Q +   P P TG    +QPRP G               
Sbjct: 583 GGQQ-RQGPPQKPPGPA-GPTRQASQAGPVPRTGPPTTQQPRPSG--------------P 626

Query: 133 APARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQA 173
            PA RP   +  +P      P       P  P L  +P QA
Sbjct: 627 GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQA 667



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 64/231 (27%), Positives = 89/231 (38%), Gaps = 43/231 (18%)

Query: 4   ERILNLYGKNYKPQDQSPPSPQRDS-GLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSA 62
           E ++N   +    Q Q   SP R S G TP       P +   PL  +   + +GP    
Sbjct: 408 ELVVNKMAQALPRQRQRDASPGRGSHGQTPS------PGAL--PLGRQTSQQPAGPPAQQ 459

Query: 63  PSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGP-----CAQPAGT-----CPPPPTGEKQ 112
             P   G   P   P+R  +G P Q+  P  G         PAG+      P P +  +Q
Sbjct: 460 RPPPQGGPPQPGPGPQR--QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517

Query: 113 PRPHGFRCSHG-SKRAPALLGAPARRPPAHIPAQPRWPRLQ---PVAKRR---ARPVPPG 165
           P       + G  +++  + G P   P A  PA P  P+ Q   P A R+   + P PP 
Sbjct: 518 PASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS-PQRQAGPPQATRQTSVSGPAPPK 576

Query: 166 LPGAPK--QAALTPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGP 214
             GAP   Q    P ++P  PA    +AS            Q G +  TGP
Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQAS------------QAGPVPRTGP 615



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 39/131 (29%), Positives = 49/131 (37%), Gaps = 26/131 (19%)

Query: 22  PSPQRDSGLTPERDRPDWPRSFKPPLS---PEKGTKASGPQTSAPSPRDPGLHTPPCSPR 78
           PSPQR +G  P+  R        PP +   P  G +  GP    P P  P        P 
Sbjct: 552 PSPQRQAG-PPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV 610

Query: 79  RGRRGRPT-QEVCPA-PGPCAQP--------AGTCPPPPTGEKQPRPHGFRCSHGSKRAP 128
             R G PT Q+  P+ PGP  +P        +   PPP T      PH           P
Sbjct: 611 P-RTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPH-----------P 658

Query: 129 ALLGAPARRPP 139
            L  +PA+  P
Sbjct: 659 QLKASPAQAQP 669


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 60/199 (30%), Positives = 66/199 (33%), Gaps = 55/199 (27%)

Query: 18   DQSPPSPQRDSGLTPERD-------RPDWPRSFKPPLSPEKGTKASGPQTSA-------P 63
            D  PP P    GL  ER         P  PR  K P  P   +   GP  +        P
Sbjct: 1196 DVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIP 1255

Query: 64   SPRDPGLHTPPCSPRRGRRGRPTQEVCPA--------PGPCAQPAGTCPPPP-------- 107
             P  PG   PP     G RG P     P         PG C  P    PP P        
Sbjct: 1256 DPGPPGDQGPPGPD--GPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKG 1313

Query: 108  -------TGEKQP-------RPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQP 153
                    G+K P        PHGF    G K  P   G P R+ P  +P     PR +P
Sbjct: 1314 FPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLP---GPPGRKGPTGLPG----PRGEP 1366

Query: 154  VAKRRARPVP--PGLPGAP 170
                     P  PGLPGAP
Sbjct: 1367 GPPADVDDCPRIPGLPGAP 1385



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 56/199 (28%), Positives = 64/199 (32%), Gaps = 47/199 (23%)

Query: 11   GKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPE-KGTKASGPQTSAPSPRDP- 68
            G   +P D  PP P    GL      P  P +  PP  P   G          P P+ P 
Sbjct: 852  GGKGQPGDVGPPGPAGMKGLP---GLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPR 908

Query: 69   GLHTPPCSPRRGRRGRPTQEVCPA----PGPCAQPA-----------GTCPPP------- 106
            GL   P  P  G RG+P  E CP     PG                 G   PP       
Sbjct: 909  GLPGFPGFP--GERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMA 966

Query: 107  -------PTGEKQPRPHGFRCSHGSKRAPALLGA---PARRPPAHIPAQPRWPRLQPVAK 156
                   P     P   GF    G K  P + G    P R  P      P + R +P  K
Sbjct: 967  IISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGP------PGFHRGEPGEK 1020

Query: 157  RRARPVPPGLPGAPKQAAL 175
               +P PPG PG P    L
Sbjct: 1021 --GQPGPPGPPGPPGSTGL 1037



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 50/179 (27%), Positives = 59/179 (32%), Gaps = 41/179 (22%)

Query: 36   RPDWPRSFKPPLSPEK----GTKASGPQTSAPSPR----DPGLHTPPC------SP---- 77
            RP  P S  PP  P      G +    +   P PR    DPG+  PP       SP    
Sbjct: 1119 RPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNG 1178

Query: 78   ------RRGRRGRPTQEVCPAPGPCAQPA-----------GTCPPPPTGEKQPRPHGFRC 120
                  ++G +G         PGP   P            G  PP P G+K P       
Sbjct: 1179 LHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPG----- 1233

Query: 121  SHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKR-RARPVPPGLPGAPKQAALTPG 178
              GS   P   GA  R P       P   +  P     R  P PPGLPG+       PG
Sbjct: 1234 PPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPG 1292



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 53/182 (29%), Positives = 65/182 (35%), Gaps = 33/182 (18%)

Query: 57  GPQTSAPSPRDPGLHTPPC-SPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRP 115
           GP+        PG+  PP  S  RG  G P Q     PG    P    P  P G+ QP  
Sbjct: 807 GPKGREGHAGFPGVPGPPGHSCERGAPGIPGQ-----PGLPGYPGS--PGAPGGKGQPGD 859

Query: 116 HGFRCSHGSKRAPALLGAPARRPPAHIPA--------------QPRWPRLQP----VAKR 157
            G     G K  P L G P    P  +P                P+ PR  P        
Sbjct: 860 VGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGE 919

Query: 158 RARPVPPGLPGA---PKQAALT--PGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEET 212
           R +P   G PGA   P +  ++  PG R L  A  A     D+   +   I Q+G   E 
Sbjct: 920 RGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDE--GEMAIISQKGTPGEP 977

Query: 213 GP 214
           GP
Sbjct: 978 GP 979



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 40/161 (24%), Positives = 50/161 (31%), Gaps = 20/161 (12%)

Query: 11   GKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGL 70
            G+  +P    PP P   +GL      P  P                G Q    SP  PG 
Sbjct: 1018 GEKGQPGPPGPPGPPGSTGLRGFIGFPGLP----------------GDQGEPGSPGPPGF 1061

Query: 71   H-TPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPA 129
                     +G +G P     P PGP  +P     P   G    +  G     G + +P 
Sbjct: 1062 SGIDGARGPKGNKGDPASHFGP-PGPKGEPGSPGCPGHFGASGEQ--GLPGIQGPRGSPG 1118

Query: 130  LLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAP 170
              G P    P   P     P L+        P P GL G P
Sbjct: 1119 RPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDP 1159



 Score = 35.8 bits (81), Expect = 0.054
 Identities = 43/160 (26%), Positives = 53/160 (33%), Gaps = 9/160 (5%)

Query: 18  DQSPPSPQRDSGLTPERDRPDWPRSFKPP-----LSPEKGTKAS-GPQTSAPSPRDPGLH 71
           D  PP  +   GL P +     P   K       +S  KG K   GP      P  PG H
Sbjct: 528 DPGPPGAEGPPGL-PGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSH 586

Query: 72  -TPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPAL 130
                +  +G  G P       PG    P    PP   G   P   GF    G +  P +
Sbjct: 587 GRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGV 646

Query: 131 LGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAP 170
            G P  R P  +  Q +   +        R  PPG  G P
Sbjct: 647 PGHPGVRGPDGLKGQ-KGDTISCNVTYPGRHGPPGFDGPP 685



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 45/157 (28%), Positives = 54/157 (34%), Gaps = 29/157 (18%)

Query: 16   PQDQSPPSPQRDSGLT--PERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTP 73
            P    PP P    G      +D    P  F  P          GP      P + GL  P
Sbjct: 1300 PGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGP---------QGPHGFPGPPGEKGLPGP 1350

Query: 74   PCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGA 133
            P     GR+G PT      PGP  +P     PP   +  PR  G   + G +     +G 
Sbjct: 1351 P-----GRKG-PTG----LPGPRGEPG----PPADVDDCPRIPGLPGAPGMRGPEGAMGL 1396

Query: 134  PARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAP 170
            P  R P+  P     P L     RR     PG PG P
Sbjct: 1397 PGMRGPSG-PGCKGEPGLD---GRRGVDGVPGSPGPP 1429



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 36/111 (32%), Positives = 44/111 (39%), Gaps = 20/111 (18%)

Query: 65  PRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSH-- 122
           P  PG+   P  P +G  G P       PG   +     PP P G    RP G  C+   
Sbjct: 352 PGPPGVLVTPPLPLKGPPGDPG-----FPGRYGETGDVGPPGPPG-LLGRP-GEACAGMI 404

Query: 123 ---GSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAP 170
              G +  P L G P     A IP +P     +P      +P  PGLPGAP
Sbjct: 405 GPPGPQGFPGLPGLPGE---AGIPGRPDSAPGKP-----GKPGSPGLPGAP 447



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 51/206 (24%), Positives = 63/206 (30%), Gaps = 51/206 (24%)

Query: 16  PQDQSPPSPQRDSGLTPE---RDRPDWPRSFKPPLSP-------------EKGTKASGPQ 59
           P  +  P PQ   GL+     + RP  P + + P  P             EKG+   GP 
Sbjct: 685 PGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPP 744

Query: 60  TSAPSPRDPGLHTPPCSPRRGRRGRPTQE---------------VCP-APGPCAQPAGTC 103
               SP   G    P  P  G  G P +                 CP A GP   P    
Sbjct: 745 GPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLG 804

Query: 104 PPPPTGEK-------QPRPHGFRCSHGSKRAPALLGAP----------ARRPPAHI--PA 144
              P G +        P P G  C  G+   P   G P           +  P  +  P 
Sbjct: 805 LKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPG 864

Query: 145 QPRWPRLQPVAKRRARPVPPGLPGAP 170
                 L  +  R     PPGLPG P
Sbjct: 865 PAGMKGLPGLPGRPGAHGPPGLPGIP 890



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 18/107 (16%)

Query: 22   PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGR 81
            P P+ + G  P  D  D PR   P L    G +  GP+ +   P   G   P C    G 
Sbjct: 1360 PGPRGEPG--PPADVDDCPRI--PGLPGAPGMR--GPEGAMGLPGMRGPSGPGCKGEPGL 1413

Query: 82   RGRPTQEVCP-APGPCAQ---------PAGTCPPPPTGEKQPRPHGF 118
             GR   +  P +PGP  +         P G  PP P G+  P P GF
Sbjct: 1414 DGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGD--PGPKGF 1458



 Score = 32.3 bits (72), Expect = 0.60
 Identities = 70/292 (23%), Positives = 91/292 (31%), Gaps = 37/292 (12%)

Query: 11  GKNYKPQDQSPPSPQRDSGLTPERDR----PDWPRSFK--PPLSPEKGTKASGPQTSAPS 64
           G+  +  D  PP P    G   E       P  P+ F   P L  E G     P ++   
Sbjct: 376 GRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGR-PDSAPGK 434

Query: 65  PRDPGLHTPPCSPRRGRRGRPTQEV--CPA--PGPCAQPAGTCPPPPTGEKQPRPHG--F 118
           P  PG    P +P  G +G P   V  C    PGP        PP   G K  + +    
Sbjct: 435 PGKPGSPGLPGAP--GLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLC 492

Query: 119 RCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPG 178
            C  G    P   G P R+        P W         +  P PPG  G P      PG
Sbjct: 493 ACEPGPMGPPGPPGLPGRQGSKGDLGLPGW------LGTKGDPGPPGAEGPPG----LPG 542

Query: 179 RRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAG--GC 236
           +      A  P  ++  +  D      +G   E GP        +         AG  G 
Sbjct: 543 KH----GASGPPGNKGAK-GDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGD 597

Query: 237 PSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTP-----RGRPGIPAH 283
           P       + T     +P P      +    P     P     RG PG+P H
Sbjct: 598 PGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGH 649



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 4/87 (4%)

Query: 55  ASGPQTSAPSPRDPGLHTPPCSP-RRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQP 113
           A GP      P +PGL  PP  P R G +G P   V    G   +      P PT   +P
Sbjct: 203 AGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEP 262

Query: 114 RPHG-FRCSHGSKRAPALLGAPARRPP 139
                ++   G K  P ++G P   PP
Sbjct: 263 PDFCLYKGEKGIKGIPGMVGLPG--PP 287



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 37/122 (30%), Positives = 41/122 (33%), Gaps = 26/122 (21%)

Query: 67  DPGLHT---PPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHG 123
           DPGL     P   P  G RG P       PG    P      PP     P  +G     G
Sbjct: 333 DPGLFGLIGPKGDP--GNRGHPGP-----PGVLVTPPLPLKGPPGDPGFPGRYGETGDVG 385

Query: 124 SKRAPALLGAPARRPPAHI-PAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPL 182
               P LLG P       I P  P+                PGLPG P +A + PGR   
Sbjct: 386 PPGPPGLLGRPGEACAGMIGPPGPQGF--------------PGLPGLPGEAGI-PGRPDS 430

Query: 183 TP 184
            P
Sbjct: 431 AP 432


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 56/194 (28%), Positives = 73/194 (37%), Gaps = 35/194 (18%)

Query: 31  TPERDRPDWPR-SFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGR-------- 81
           +PER +P  P  + KP +S   G  ++     APSP  PG    P   +R R        
Sbjct: 653 SPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAH 712

Query: 82  ---RGRPTQEVCPAPGPCAQP------AGTCPPPPTGEKQPRPHGFRCSHGSKRAPA--- 129
               G P     P P P   P      A   PP       PRP G   +HG +R+PA   
Sbjct: 713 TVEHGSPRTR-DPTPRPPGLPEEATALAAPSPPRARARAAPRPLG---AHGRRRSPAKRA 768

Query: 130 ----LLGAPARRPP-----AHIPAQPRWPRLQPVAKRRA-RPVPPGLPGAPKQAALTPGR 179
               +L A  R        A +    + PR +P   ++A R VPP  P     A  TPG 
Sbjct: 769 EAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGP 828

Query: 180 RPLTPAAFAPKASR 193
                   AP+  R
Sbjct: 829 EKAATDLPAPETPR 842


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 56/194 (28%), Positives = 73/194 (37%), Gaps = 35/194 (18%)

Query: 31  TPERDRPDWPR-SFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGR-------- 81
           +PER +P  P  + KP +S   G  ++     APSP  PG    P   +R R        
Sbjct: 648 SPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAH 707

Query: 82  ---RGRPTQEVCPAPGPCAQP------AGTCPPPPTGEKQPRPHGFRCSHGSKRAPA--- 129
               G P     P P P   P      A   PP       PRP G   +HG +R+PA   
Sbjct: 708 TVEHGSPRTR-DPTPRPPGLPEEATALAAPSPPRARARAAPRPLG---AHGRRRSPAKRA 763

Query: 130 ----LLGAPARRPP-----AHIPAQPRWPRLQPVAKRRA-RPVPPGLPGAPKQAALTPGR 179
               +L A  R        A +    + PR +P   ++A R VPP  P     A  TPG 
Sbjct: 764 EAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGP 823

Query: 180 RPLTPAAFAPKASR 193
                   AP+  R
Sbjct: 824 EKAATDLPAPETPR 837


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 54/189 (28%), Positives = 75/189 (39%), Gaps = 37/189 (19%)

Query: 11  GKNYKPQDQS-PPSPQRDSGLTPERDRPDWP---------RSFKPPL-SPEKGTKASGPQ 59
           G+ + P  Q   P+PQ  S   P R  P  P         RS  PP  SP++    + P 
Sbjct: 331 GQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPS 390

Query: 60  TSAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEK-------- 111
             +P P+      P C     +R  P    CPAP P  +P    PPPP GE+        
Sbjct: 391 CPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQP--RPP---PPPPPGERTLAERAYA 445

Query: 112 QPRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARP-------VPP 164
           +P  H  +     +R+ + L   A    A+  A P W  LQ  A    +P         P
Sbjct: 446 KPPSHHVKAGFQGRRSYSELAEGA----AYAGASPPW--LQAEAATLPKPRAYGSELYGP 499

Query: 165 GLPGAPKQA 173
           G P +P++A
Sbjct: 500 GRPLSPRRA 508



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 47/168 (27%), Positives = 62/168 (36%), Gaps = 12/168 (7%)

Query: 58  PQTSAPSPRDPGLHTPPCSPRRG--RRGRPTQEVCPAPGPCAQPAG-TCPPPPTGEKQPR 114
           P    PSP  P    PPC P +    + R     CP+P     PA  +CP P    + P 
Sbjct: 343 PAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPV 402

Query: 115 PHGFRCSHGSKRAPA--LLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQ 172
           P   +     +R+P      AP  RPP   P   R    +  AK  +  V  G  G    
Sbjct: 403 PPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSY 462

Query: 173 AALTPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEET-GPARQIS 219
           + L  G      AA+A  +    Q   +T    R    E  GP R +S
Sbjct: 463 SELAEG------AAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLS 504


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 72/275 (26%), Positives = 96/275 (34%), Gaps = 36/275 (13%)

Query: 11  GKNYKPQDQSPPSP--QRDSGLTPERDRPDWPRS----FKPPLSPEKGTKASGPQTSAPS 64
           G++ KP   SP  P  Q+ +   P   +P   +S     KPP  P   TK        P 
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK--------PL 342

Query: 65  PRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGS 124
            + PG   PP  P  G    P Q + PA  P  Q     P      +QP P       G 
Sbjct: 343 AQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKP----SSEQPGPKALAQPPGV 397

Query: 125 KRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTP 184
            + PA    PA +PP      P+     P+A++     P   PG  K     PG   + P
Sbjct: 398 GKTPAQQPGPA-KPPTQQVGTPK-----PLAQQPGLQSPAKAPGPTKTPVQQPGPGKI-P 450

Query: 185 AAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLASSR 244
           A  A       Q T  T    +       P +Q        Q  G+ +    PS    S 
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP---PSQQPGS- 506

Query: 245 EQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPG 279
             T  P   P P+  SP      P ++  P  +PG
Sbjct: 507 --TKPPPQQPGPAKPSPQQ----PGSTKPPSQQPG 535



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 52/194 (26%), Positives = 73/194 (37%), Gaps = 27/194 (13%)

Query: 15  KPQDQSP--PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRD--PGL 70
           KP  Q P   SP +  G  P +     P   K P       K S  QT    P    PG 
Sbjct: 419 KPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476

Query: 71  HTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPAL 130
             PP   + G    P Q+   A  P  QP  T PPP    +QP P     +  S + P  
Sbjct: 477 AKPP-PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP----QQPGP-----AKPSPQQPGS 526

Query: 131 LGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAPK 190
              P+++P +  P+  +    +P A++  +PV           + T   +PL P   +P 
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV-----------SQTGSGKPLQPPTVSPS 575

Query: 191 ASRDQQVTDSTTIC 204
           A +        TIC
Sbjct: 576 AKQPPSQGLPKTIC 589



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 67/283 (23%), Positives = 94/283 (33%), Gaps = 49/283 (17%)

Query: 15  KPQDQSP----PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGL 70
           KP  Q P    P PQ+     P +  P  P S KPP       K S  Q   PSP  P  
Sbjct: 498 KPPSQQPGSTKPPPQQPG---PAKPSPQQPGSTKPPSQQPGSAKPSAQQ---PSPAKPSA 551

Query: 71  HTPPCSPRRGRRGRPTQEVCPAPG---PCAQ--PAGTCPPPPTGE---KQPRPHGFR-CS 121
                   +   G+P Q    +P    P +Q  P   CP   T E     P    F  C+
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 122 HGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRP 181
                  +L G     P  H+     W  L    KR        +P +P+    T    P
Sbjct: 612 ECQTTVCSLCGF---NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA---P 665

Query: 182 LTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLA 241
           +T  +   K+S   Q T           ++  P + +S   E  +          P  L 
Sbjct: 666 VTTTSAVSKSSPQPQQTSPK--------KDAAPKQDLSKAPEPKK----------PPPLV 707

Query: 242 SSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHK 284
                   P L+ SPS+ +    EA   +   P   P +P+ +
Sbjct: 708 KQ------PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744



 Score = 35.0 bits (79), Expect = 0.092
 Identities = 73/296 (24%), Positives = 96/296 (32%), Gaps = 59/296 (19%)

Query: 16  PQDQSPPSP---QRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHT 72
           P  Q PP P   Q+  G  P + +   P+S      PEK  K+  P T  P      +  
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQ-QDGTPKSISSQ-QPEK-IKSQPPGTGKP------IQG 260

Query: 73  PPCSPRRGRRGRPTQEVCPAP---------GPCAQPAGTCPPPPTGEKQPRPHGFRCSHG 123
           P  +P+      P Q     P         G   +P+   P  P  + QP P        
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ-QPTP-------- 311

Query: 124 SKRAPALLGAPARRPPAHIPAQP--RWPRLQPVAKRRARPVPPGLPGAPKQAALT--PGR 179
                   G P  + P H  +QP    P  QP    +     PG    P Q   T  P  
Sbjct: 312 --------GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 180 RPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSS 239
           +PL PA   P A +      S+        E+ GP            GVG   A   P  
Sbjct: 364 QPLGPAK--PPAQQTGSEKPSS--------EQPGPKALAQP-----PGVGKTPAQQ-PGP 407

Query: 240 LASSREQTHSPH-LYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQE 294
                +Q  +P  L   P   SP+    P    V   G   IPA + G      Q+
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463



 Score = 32.0 bits (71), Expect = 0.78
 Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 26/134 (19%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPC 75
            P    PP P     L P       P S KP + P+K    + P T+A +P    + T   
Sbjct: 2413 PPPPPPPPPPPPPPLPP-------PTSPKPTILPKKKLTVASPVTTA-TPLFDAVTTLET 2464

Query: 76   SPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPA 135
            +      G P   +C           T PPP   +    P G   +H  +        P+
Sbjct: 2465 TAVLRSNGLPVTRICT----------TAPPPVPPKPSSIPSGLVFTHRPE--------PS 2506

Query: 136  RRPPAHIPAQPRWP 149
            + P A  P  P+ P
Sbjct: 2507 KPPIAPKPVIPQLP 2520



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 41/185 (22%), Positives = 60/185 (32%), Gaps = 26/185 (14%)

Query: 132 GAPARRPPAHIPAQPRWPRLQPV-----AKRRARPVPPGLPGAP-----------KQAAL 175
           G P    P      P   R Q +      K+  RP  PG P  P           +    
Sbjct: 65  GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124

Query: 176 TPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGG 235
            PGR P T +    K+  D +    +++    L E       ++ L  VS  V  F    
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSE-------VNALSAVSSVVNKFNPFD 177

Query: 236 CPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEA 295
             S   +S+E+T             P     PP     P+    IP  +      + Q+ 
Sbjct: 178 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK---PIPKQQGPGRDPLQQDG 234

Query: 296 TYKSL 300
           T KS+
Sbjct: 235 TPKSI 239



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 54/286 (18%), Positives = 95/286 (33%), Gaps = 52/286 (18%)

Query: 20   SPPSPQRDSGLT-PERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDP---------- 68
            +PP P+  +G T P   +   P+      S   G+    P++   +P++           
Sbjct: 877  TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 69   -------GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCS 121
                    L +    P    +  P   +  AP P   P    PP  TG+  P P      
Sbjct: 937  SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP------ 990

Query: 122  HGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPP------GLPGAPKQAAL 175
                 A ++      + PA    +P+  +   V +      PP       L   P++A L
Sbjct: 991  -----AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045

Query: 176  -TPGRRPLTPAAFAPK-------ASRDQQVTDSTTICQRGLIEETG--PARQISDLCEVS 225
             T   +   P +  P         S+D    ++ T C+  +    G  P   ++++ E  
Sbjct: 1046 PTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQE-- 1103

Query: 226  QGVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANS 271
                 +    C +  A S +      + P+PS    S    P  +S
Sbjct: 1104 -----WLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESS 1144


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 72/275 (26%), Positives = 96/275 (34%), Gaps = 36/275 (13%)

Query: 11  GKNYKPQDQSPPSP--QRDSGLTPERDRPDWPRS----FKPPLSPEKGTKASGPQTSAPS 64
           G++ KP   SP  P  Q+ +   P   +P   +S     KPP  P   TK        P 
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK--------PL 342

Query: 65  PRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGS 124
            + PG   PP  P  G    P Q + PA  P  Q     P      +QP P       G 
Sbjct: 343 AQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKP----SSEQPGPKALAQPPGV 397

Query: 125 KRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTP 184
            + PA    PA +PP      P+     P+A++     P   PG  K     PG   + P
Sbjct: 398 GKTPAQQPGPA-KPPTQQVGTPK-----PLAQQPGLQSPAKAPGPTKTPVQQPGPGKI-P 450

Query: 185 AAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLASSR 244
           A  A       Q T  T    +       P +Q        Q  G+ +    PS    S 
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP---PSQQPGS- 506

Query: 245 EQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPG 279
             T  P   P P+  SP      P ++  P  +PG
Sbjct: 507 --TKPPPQQPGPAKPSPQQ----PGSTKPPSQQPG 535



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 52/194 (26%), Positives = 73/194 (37%), Gaps = 27/194 (13%)

Query: 15  KPQDQSP--PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRD--PGL 70
           KP  Q P   SP +  G  P +     P   K P       K S  QT    P    PG 
Sbjct: 419 KPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476

Query: 71  HTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPAL 130
             PP   + G    P Q+   A  P  QP  T PPP    +QP P     +  S + P  
Sbjct: 477 AKPP-PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP----QQPGP-----AKPSPQQPGS 526

Query: 131 LGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAPK 190
              P+++P +  P+  +    +P A++  +PV           + T   +PL P   +P 
Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV-----------SQTGSGKPLQPPTVSPS 575

Query: 191 ASRDQQVTDSTTIC 204
           A +        TIC
Sbjct: 576 AKQPPSQGLPKTIC 589



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 67/283 (23%), Positives = 94/283 (33%), Gaps = 49/283 (17%)

Query: 15  KPQDQSP----PSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGL 70
           KP  Q P    P PQ+     P +  P  P S KPP       K S  Q   PSP  P  
Sbjct: 498 KPPSQQPGSTKPPPQQPG---PAKPSPQQPGSTKPPSQQPGSAKPSAQQ---PSPAKPSA 551

Query: 71  HTPPCSPRRGRRGRPTQEVCPAPG---PCAQ--PAGTCPPPPTGE---KQPRPHGFR-CS 121
                   +   G+P Q    +P    P +Q  P   CP   T E     P    F  C+
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 122 HGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRP 181
                  +L G     P  H+     W  L    KR        +P +P+    T    P
Sbjct: 612 ECQTTVCSLCGF---NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA---P 665

Query: 182 LTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLA 241
           +T  +   K+S   Q T           ++  P + +S   E  +          P  L 
Sbjct: 666 VTTTSAVSKSSPQPQQTSPK--------KDAAPKQDLSKAPEPKK----------PPPLV 707

Query: 242 SSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHK 284
                   P L+ SPS+ +    EA   +   P   P +P+ +
Sbjct: 708 KQ------PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744



 Score = 35.0 bits (79), Expect = 0.092
 Identities = 73/296 (24%), Positives = 96/296 (32%), Gaps = 59/296 (19%)

Query: 16  PQDQSPPSP---QRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHT 72
           P  Q PP P   Q+  G  P + +   P+S      PEK  K+  P T  P      +  
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQ-QDGTPKSISSQ-QPEK-IKSQPPGTGKP------IQG 260

Query: 73  PPCSPRRGRRGRPTQEVCPAP---------GPCAQPAGTCPPPPTGEKQPRPHGFRCSHG 123
           P  +P+      P Q     P         G   +P+   P  P  + QP P        
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ-QPTP-------- 311

Query: 124 SKRAPALLGAPARRPPAHIPAQP--RWPRLQPVAKRRARPVPPGLPGAPKQAALT--PGR 179
                   G P  + P H  +QP    P  QP    +     PG    P Q   T  P  
Sbjct: 312 --------GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 180 RPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSS 239
           +PL PA   P A +      S+        E+ GP            GVG   A   P  
Sbjct: 364 QPLGPAK--PPAQQTGSEKPSS--------EQPGPKALAQP-----PGVGKTPAQQ-PGP 407

Query: 240 LASSREQTHSPH-LYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQE 294
                +Q  +P  L   P   SP+    P    V   G   IPA + G      Q+
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463



 Score = 32.0 bits (71), Expect = 0.78
 Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 26/134 (19%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPC 75
            P    PP P     L P       P S KP + P+K    + P T+A +P    + T   
Sbjct: 2413 PPPPPPPPPPPPPPLPP-------PTSPKPTILPKKKLTVASPVTTA-TPLFDAVTTLET 2464

Query: 76   SPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLGAPA 135
            +      G P   +C           T PPP   +    P G   +H  +        P+
Sbjct: 2465 TAVLRSNGLPVTRICT----------TAPPPVPPKPSSIPSGLVFTHRPE--------PS 2506

Query: 136  RRPPAHIPAQPRWP 149
            + P A  P  P+ P
Sbjct: 2507 KPPIAPKPVIPQLP 2520



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 41/185 (22%), Positives = 60/185 (32%), Gaps = 26/185 (14%)

Query: 132 GAPARRPPAHIPAQPRWPRLQPV-----AKRRARPVPPGLPGAP-----------KQAAL 175
           G P    P      P   R Q +      K+  RP  PG P  P           +    
Sbjct: 65  GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124

Query: 176 TPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGG 235
            PGR P T +    K+  D +    +++    L E       ++ L  VS  V  F    
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSE-------VNALSAVSSVVNKFNPFD 177

Query: 236 CPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPAHKLGASSAVCQEA 295
             S   +S+E+T             P     PP     P+    IP  +      + Q+ 
Sbjct: 178 LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK---PIPKQQGPGRDPLQQDG 234

Query: 296 TYKSL 300
           T KS+
Sbjct: 235 TPKSI 239



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 54/286 (18%), Positives = 95/286 (33%), Gaps = 52/286 (18%)

Query: 20   SPPSPQRDSGLT-PERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDP---------- 68
            +PP P+  +G T P   +   P+      S   G+    P++   +P++           
Sbjct: 877  TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 69   -------GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCS 121
                    L +    P    +  P   +  AP P   P    PP  TG+  P P      
Sbjct: 937  SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP------ 990

Query: 122  HGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPP------GLPGAPKQAAL 175
                 A ++      + PA    +P+  +   V +      PP       L   P++A L
Sbjct: 991  -----AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045

Query: 176  -TPGRRPLTPAAFAPK-------ASRDQQVTDSTTICQRGLIEETG--PARQISDLCEVS 225
             T   +   P +  P         S+D    ++ T C+  +    G  P   ++++ E  
Sbjct: 1046 PTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQE-- 1103

Query: 226  QGVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAPPANS 271
                 +    C +  A S +      + P+PS    S    P  +S
Sbjct: 1104 -----WLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESS 1144


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 72/282 (25%), Positives = 93/282 (32%), Gaps = 45/282 (15%)

Query: 16  PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRDPGLHTPPC 75
           P    PP P     L P     D  ++ KP L+P        P    P    PGL   P 
Sbjct: 223 PPPPPPPPPPTPPPLPPASVLSD--KAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280

Query: 76  SPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGS-----KRAPAL 130
           SP      +  QE  PAP P   P  +C P  +    P P G   S  +      ++P+ 
Sbjct: 281 SP-----AQDAQEP-PAPPPPLPPYASCSPRASLPAPPLP-GVNSSSETPPPLPPKSPSF 333

Query: 131 LGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAPK 190
              P +     +PA P  P  QP  +++    P    G        P R P T       
Sbjct: 334 QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTEL----- 388

Query: 191 ASRDQQVTDSTTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLASSREQTHSP 250
           +S+ QQ T  T   Q G     G    I D                      S+   HS 
Sbjct: 389 SSKSQQATAWTPTQQPGGQLRNGSLHIIDDF--------------------ESKFTFHSV 428

Query: 251 HLYPSPSSSSPSSWEAPPANSVTPRGR---PGIPAHKLGASS 289
             +P P    P     P   S  PR R   P + A  +G SS
Sbjct: 429 EDFPPPDEYKPCQKIYP---SKIPRSRTPGPWLQAEAVGQSS 467



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 74/273 (27%), Positives = 86/273 (31%), Gaps = 48/273 (17%)

Query: 52  GTKASGPQTSAPSPRDP-----GLHTPPCSPRRGR--------RGRPTQEVCPAPGPCAQ 98
           G    GP + APSPR P     G   PP SPR G         R  P +   PAP P   
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179

Query: 99  PAGTCPPPPTGEKQPRPHGFRCSHGSKRAPALLG--------APARRPPAHIPAQPRWPR 150
           P    PPPP     P     +    S   P   G         P   PP   P  P  P 
Sbjct: 180 PP---PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPP 236

Query: 151 LQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAP--KASRDQQVTDSTTICQRGL 208
           L P +    + V P L  AP      P   PL P    P  KA       D+        
Sbjct: 237 LPPASVLSDKAVKPQL--APLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQ------- 287

Query: 209 IEETGPARQISDLCEVSQGVGAFRAGGCPSSLASSREQTHSPHLYPS----PSSSSPSSW 264
            E   P   +      S    +  A   P   +SS      P   PS    P  +   + 
Sbjct: 288 -EPPAPPPPLPPYASCSPR-ASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQAL 345

Query: 265 EAPPANSVTP-------RGRPGIPAHKLGASSA 290
            APPA   +         GRPG    KL    A
Sbjct: 346 PAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA 378



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 47/170 (27%), Positives = 56/170 (32%), Gaps = 31/170 (18%)

Query: 46  PLSPEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPP 105
           P  P        P    P P    + TP  SP  G   +    V   P PCA P    PP
Sbjct: 172 PAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP-GPLTKGNLPVVAPPVPCAPPPPPPPP 230

Query: 106 PPTGE-------------------------KQPRPHGFRCSH-GSKRAPALLGAPARRPP 139
           PPT                             P P    C + G K  PA     A+ PP
Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP 290

Query: 140 AHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFAP 189
           A  P  P +    P   R + P PP LPG    +   P   P +P+  AP
Sbjct: 291 APPPPLPPYASCSP---RASLPAPP-LPGVNSSSETPPPLPPKSPSFQAP 336


>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
           sapiens]
          Length = 678

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 52/160 (32%), Positives = 68/160 (42%), Gaps = 19/160 (11%)

Query: 127 APALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAA 186
           AP   G+P R  P   P  P  PR  P A     P PP  PG P+    +PG R    + 
Sbjct: 84  APRRRGSPERARPPPPPPPPAPPRPPPAA-----PSPPAAPG-PRGGGASPGARR---SD 134

Query: 187 FAPKASRDQQVTDSTTICQRGLIEETGPARQISD---LCEVSQGVGAFRAGGCPSSLA-S 242
           F  K       ++S T+  RGL    G AR +S+     E   G     AG  P S    
Sbjct: 135 FLQKTG-----SNSFTVHPRGLHRGAG-ARLLSNGHSAPEPRAGPANRLAGSPPGSGQWK 188

Query: 243 SREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPA 282
            + ++  P L+P PS  +PS+  A P  S TP  R  + A
Sbjct: 189 PKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSA 228



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 39/151 (25%), Positives = 50/151 (33%), Gaps = 39/151 (25%)

Query: 73  PPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKR------ 126
           PP +PRR  RG P +   P P P   P    P  P+    P P G   S G++R      
Sbjct: 81  PPAAPRR--RGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQK 138

Query: 127 ---------------------------APALLGAPARRPPAHIPAQPRW-PRLQPVAKRR 158
                                      AP     PA R     P   +W P+++      
Sbjct: 139 TGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSL 198

Query: 159 ARPVPPGLPG---APKQAALTPGRRPLTPAA 186
             P  PG P    A   A+ TP +R    AA
Sbjct: 199 HPPPSPGTPSATPASPPASATPSQRQCVSAA 229


>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
           sapiens]
          Length = 650

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 52/160 (32%), Positives = 68/160 (42%), Gaps = 19/160 (11%)

Query: 127 APALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAA 186
           AP   G+P R  P   P  P  PR  P A     P PP  PG P+    +PG R    + 
Sbjct: 84  APRRRGSPERARPPPPPPPPAPPRPPPAA-----PSPPAAPG-PRGGGASPGARR---SD 134

Query: 187 FAPKASRDQQVTDSTTICQRGLIEETGPARQISD---LCEVSQGVGAFRAGGCPSSLA-S 242
           F  K       ++S T+  RGL    G AR +S+     E   G     AG  P S    
Sbjct: 135 FLQKTG-----SNSFTVHPRGLHRGAG-ARLLSNGHSAPEPRAGPANRLAGSPPGSGQWK 188

Query: 243 SREQTHSPHLYPSPSSSSPSSWEAPPANSVTPRGRPGIPA 282
            + ++  P L+P PS  +PS+  A P  S TP  R  + A
Sbjct: 189 PKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSA 228



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 39/151 (25%), Positives = 50/151 (33%), Gaps = 39/151 (25%)

Query: 73  PPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKR------ 126
           PP +PRR  RG P +   P P P   P    P  P+    P P G   S G++R      
Sbjct: 81  PPAAPRR--RGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQK 138

Query: 127 ---------------------------APALLGAPARRPPAHIPAQPRW-PRLQPVAKRR 158
                                      AP     PA R     P   +W P+++      
Sbjct: 139 TGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSL 198

Query: 159 ARPVPPGLPG---APKQAALTPGRRPLTPAA 186
             P  PG P    A   A+ TP +R    AA
Sbjct: 199 HPPPSPGTPSATPASPPASATPSQRQCVSAA 229


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 55/184 (29%), Positives = 73/184 (39%), Gaps = 24/184 (13%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWP-------RSFKPPLSPEKGTKASGPQTSAPSPRDP 68
            P +  PP P  +   T     P  P       +  KPP+SP+       P  + P P+  
Sbjct: 1188 PPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPK-------PVLTQPVPKLQ 1240

Query: 69   GLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAP 128
            G  T P S +    G  + EV  A G     +   PPPPT  K  +      S  +  +P
Sbjct: 1241 GSPT-PTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSP 1299

Query: 129  ALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFA 188
            A   +PAR+PPA +   P  P         A P  P  PGAP  A   P + P   AA A
Sbjct: 1300 A--PSPARQPPAALAKPPGTP-----PSLGASPAKPPSPGAP--ALHVPAKPPRAAAAAA 1350

Query: 189  PKAS 192
              A+
Sbjct: 1351 AAAA 1354



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 55/201 (27%), Positives = 73/201 (36%), Gaps = 47/201 (23%)

Query: 19  QSPPSPQRDSGLTPERDRPDWPRSFKPP-LSPEKGTKASGPQTSAPSPRDPGLHTPPCSP 77
           +SPP P+     TP   +     +F+   LS E     +GP    P+   P  H PP +P
Sbjct: 632 ESPPPPEP----TPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPP-TP 686

Query: 78  R-----------RGRRGRPTQEVC--PAPGPCAQPA---------GTCPPPPTGEKQPRP 115
           R           R R    +QE+     PGP +  +         G  P  P  E +P  
Sbjct: 687 RATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGR 746

Query: 116 HGFRCSHGSKRA--PALLGAPARRPPAHIPAQPRW-PRLQPVAKRRARPVPPGLPGAPKQ 172
           HG    H  KRA  P + G P +  P   P    + P   P   R   P   G P  P  
Sbjct: 747 HG----HSIKRASVPPVPGKPRQVLP---PGTSHFTPPQTPTKTRPGSPQALGGPHGPAP 799

Query: 173 AA---------LTPGRRPLTP 184
           A          L P  RP++P
Sbjct: 800 ATAKVKPTPQLLPPTERPMSP 820



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 70/268 (26%), Positives = 98/268 (36%), Gaps = 48/268 (17%)

Query: 49   PEKGTKASGPQTSAPSPRDPGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPPPT 108
            P+   + +GP+   P P     H    + RR    RP  E     GP   P    PPPP 
Sbjct: 1152 PKAKEREAGPE---PPPPLSVYHNGTGTVRR----RPASEQA---GPPELP----PPPPP 1197

Query: 109  GEKQPRPHGFRCSHGSKRAPALLGAPARRPPAHIPAQPRWPRLQPVAKRRARPVP----- 163
             E  P       +H     P    A   R PA  P  P+    QPV K +  P P     
Sbjct: 1198 AEPPPTD----LAHLPPLPPPEGEA---RKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKV 1250

Query: 164  --PGLPGAP--KQAALTPGRRPLTP-AAFAPKASRDQQVTDSTTICQRGLIEETGPARQI 218
              PG PG+P  K+A  TP   P++P     P A +  +          G      PARQ 
Sbjct: 1251 PLPG-PGSPEVKRAHGTP--PPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQ- 1306

Query: 219  SDLCEVSQGVGAFRAGGCPSSLASSREQTHSP-----HLYPSPSSSSPSSWEAPPANSVT 273
                         +  G P SL +S  +  SP     H+   P  ++ ++  A  A    
Sbjct: 1307 -------PPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAP 1359

Query: 274  PRG-RPGIPAHKLGASSAVCQEATYKSL 300
            P G  PG  A +    ++ C  A  +++
Sbjct: 1360 PEGASPGDSARQKLEETSACLAAALQAV 1387



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 69/289 (23%), Positives = 97/289 (33%), Gaps = 57/289 (19%)

Query: 15   KPQDQSPPSPQRDSG-LTPERDRPDWPRSFKPPLSPEKGTKA--SGPQTSAPSPRDPGLH 71
            KP+   PP     +   TP + RP  P++   P  P   T      PQ   P+ R     
Sbjct: 762  KPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPR 821

Query: 72   TPPCSPRR------------GRRGRPTQEVCPAPGPCAQPAGTCPPPPTGEKQPRP---- 115
            + P SP              G  G       P P P A P   C PP    +  RP    
Sbjct: 822  SLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPT-LCLPPEADAEPGRPKKRA 880

Query: 116  ---HGFRCSHGSKRAPALLGAPARRPPAHIP--------------AQPRWPRLQPVAKRR 158
               + +  S        LL   A  P A +               A     R Q  A R 
Sbjct: 881  HSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRP 940

Query: 159  ARPVPPGLPGAPKQAALTPGRRPLTPAAFAPKASRDQQVTDSTTICQRGLIEETGPARQI 218
             +  PP  P  PK+++          +A A     D+ V D+    + GL+      R+ 
Sbjct: 941  RKKGPP--PPPPKRSS----------SALASANLADEPVPDAEP--EDGLLGVRAQCRRA 986

Query: 219  SDLC-EVSQG-VGAFRAGGCPSSLAS----SREQTHSPHLYPSPSSSSP 261
            SDL   V  G  G+ ++      L+S     R     P  +P+P  +SP
Sbjct: 987  SDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASP 1035



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 27/85 (31%), Positives = 31/85 (36%), Gaps = 11/85 (12%)

Query: 16   PQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEK-GTKASGPQTSAPSPRDPGLHTPP 74
            P   + PSP      +P R  P      KPP +P   G   + P    PSP  P LH P 
Sbjct: 1291 PSGSAGPSPAP----SPARQPP--AALAKPPGTPPSLGASPAKP----PSPGAPALHVPA 1340

Query: 75   CSPRRGRRGRPTQEVCPAPGPCAQP 99
              PR            PAP   A P
Sbjct: 1341 KPPRAAAAAAAAAAAPPAPPEGASP 1365



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 50/207 (24%), Positives = 78/207 (37%), Gaps = 38/207 (18%)

Query: 104 PPPPTGE--KQPRPHGFRCSHGSKR------APALLGAPARRPPAHIPAQPR-WPRLQPV 154
           PP PT    + P+   F+ S  S         PA +G    +P +H+P  PR   R    
Sbjct: 636 PPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSS 695

Query: 155 AKRRARPV----------PPGLPGAP----KQAALTPGRRPLTPAAFAPKASRDQQVTDS 200
              RAR +          PPG P +P    ++  L  G  P TP    P+ +R  +    
Sbjct: 696 LGGRARHMSSSQELLGDGPPG-PSSPMSRSQEYLLDEGPAPGTP----PREARPGR--HG 748

Query: 201 TTICQRGLIEETGPARQISDLCEVSQGVGAFRAGGCPSSLASSREQTHSPHLYPSPSSS- 259
            +I +  +    G  RQ+     +  G   F     P+       Q       P+P+++ 
Sbjct: 749 HSIKRASVPPVPGKPRQV-----LPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAK 803

Query: 260 -SPSSWEAPPA-NSVTPRGRPGIPAHK 284
             P+    PP    ++PR  P  P H+
Sbjct: 804 VKPTPQLLPPTERPMSPRSLPQSPTHR 830


>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 1006

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 57/210 (27%), Positives = 76/210 (36%), Gaps = 11/210 (5%)

Query: 75  CSPRRGRRGRPTQEVCPAPG--PCAQPAGTCPPPPTGEKQPRPHG---FRCSHGSKRAPA 129
           C PR    G+P     P+     C+      PPP  G  QP  HG   FR +  S+  P 
Sbjct: 252 CRPRPCSFGQPDVGSAPSRSLRGCSLRFRNTPPPIPGSDQPSSHGRPRFRETGDSEDCPP 311

Query: 130 L-LGAPARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLPGAPKQAALTPGRRPLTPAAFA 188
              G P ++P A     P   R      R   P+P   P   K+   +P  +   P   +
Sbjct: 312 FRAGTPPQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPASKRPRPGGVS 371

Query: 189 PKASRDQQVTDSTTICQRGLIEETGPAR-QISDLCEVSQGVGAFRAGGCPSSLASSREQT 247
           P+A RD    ++  +C      ETGP + +  D     +  G  R G  P    S R   
Sbjct: 372 PEA-RDPPKGEN-PLCSSEAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPA- 428

Query: 248 HSPHLYPSPSSSSPSSWEAPPANSVTPRGR 277
             P L   P S  P     PP      R R
Sbjct: 429 -PPRLGKPPRSRPPQGLAQPPETFFFERSR 457



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 64/287 (22%), Positives = 89/287 (31%), Gaps = 39/287 (13%)

Query: 8   NLYGKNYKPQDQSPPSPQRDSGLTPERDRPDWPRSFKPPLSPEKGTKASGPQTSAPSPRD 67
           +L G + + ++  PP P  D        RP +  +      P         Q +APS   
Sbjct: 271 SLRGCSLRFRNTPPPIPGSDQ--PSSHGRPRFRETGDSEDCPPFRAGTPPQQPTAPSSEW 328

Query: 68  PGLHTPPCSPRRGRRGRPTQEVCPAPGPCAQPAGTCPPP----PTGEKQPRPHGFRCSHG 123
           PG    P +  R     P     PA  P   PA   P P    P     P+     CS  
Sbjct: 329 PGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSE 388

Query: 124 SK--------RAPALLGA--------PARRPPAHIPAQPRWPRLQPVAKRRARPVPPGLP 167
           +         R P  LG           + P   +  +P  PRL      R+RP P GL 
Sbjct: 389 AAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPAPPRLG--KPPRSRP-PQGLA 445

Query: 168 GAP-----KQAALTPGRRPLTPA--AFAPKASRDQQVTDSTTICQRGLIEETGPARQISD 220
             P     +++ L P    L  A   F+  A        +    +  L     P  Q   
Sbjct: 446 QPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDLGARPASRSSLPSAPAPPAQ--- 502

Query: 221 LCEVSQGVGAFRAGGCPSSLASSREQTHSPHLYPSPSSSSPSSWEAP 267
                       A G      ++  Q H P   PSP + +    E P
Sbjct: 503 ----QPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPTGAQQVEEDP 545


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,110,840
Number of Sequences: 37866
Number of extensions: 1494526
Number of successful extensions: 14180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 254
Number of HSP's successfully gapped in prelim test: 1516
Number of HSP's that attempted gapping in prelim test: 8151
Number of HSP's gapped (non-prelim): 5256
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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