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Search of human proteins with 119943108
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
(512 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 1018 0.0
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 823 0.0
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 745 0.0
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 739 0.0
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 739 0.0
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 702 0.0
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 693 0.0
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 590 e-168
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 590 e-168
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 516 e-146
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 201 1e-51
gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] 196 4e-50
gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] 180 2e-45
gi|95089461 discs large homolog 5 [Homo sapiens] 172 9e-43
gi|52630447 palmitoylated membrane protein 2 [Homo sapiens] 166 4e-41
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 164 2e-40
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 160 2e-39
gi|4505237 palmitoylated membrane protein 1 [Homo sapiens] 159 6e-39
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 158 1e-38
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 158 1e-38
gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens] 154 1e-37
gi|10092691 tight junction protein 3 [Homo sapiens] 129 5e-30
gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 128 1e-29
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 128 1e-29
gi|42518065 tight junction protein 2 (zona occludens 2) isoform ... 112 1e-24
gi|42518070 tight junction protein 2 (zona occludens 2) isoform ... 112 1e-24
gi|226874833 guanylate kinase 1 isoform b [Homo sapiens] 102 6e-22
gi|226874831 guanylate kinase 1 isoform a [Homo sapiens] 102 6e-22
gi|4504221 guanylate kinase 1 isoform b [Homo sapiens] 102 6e-22
gi|11545920 lin-7 homolog B [Homo sapiens] 84 4e-16
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 1018 bits (2633), Expect = 0.0
Identities = 512/512 (100%), Positives = 512/512 (100%)
Query: 1 MERARKFSGSGLAMGLGSASASAWRRASQRWAWPLRSLRPGGDAREPRKIILHKGSTGLG 60
MERARKFSGSGLAMGLGSASASAWRRASQRWAWPLRSLRPGGDAREPRKIILHKGSTGLG
Sbjct: 1 MERARKFSGSGLAMGLGSASASAWRRASQRWAWPLRSLRPGGDAREPRKIILHKGSTGLG 60
Query: 61 FNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQ 120
FNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQ
Sbjct: 61 FNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQ 120
Query: 121 SVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRD 180
SVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRD
Sbjct: 121 SVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRD 180
Query: 181 SCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKT 240
SCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKT
Sbjct: 181 SCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKT 240
Query: 241 VKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESS 300
VKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESS
Sbjct: 241 VKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESS 300
Query: 301 SKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRD 360
SKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRD
Sbjct: 301 SKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRD 360
Query: 361 NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG 420
NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG
Sbjct: 361 NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG 420
Query: 421 NAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIV 480
NAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIV
Sbjct: 421 NAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIV 480
Query: 481 QGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
QGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
Sbjct: 481 QGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 823 bits (2126), Expect = 0.0
Identities = 424/468 (90%), Positives = 430/468 (91%), Gaps = 32/468 (6%)
Query: 45 REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLR 104
REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLR
Sbjct: 382 REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLR 441
Query: 105 NATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK 164
NATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK
Sbjct: 442 NATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK 501
Query: 165 RSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVI 224
RSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVI
Sbjct: 502 RSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVI 561
Query: 225 PSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESS 284
PSKKRVEKKERARLKTVKFHARTGMIESNR FP
Sbjct: 562 PSKKRVEKKERARLKTVKFHARTGMIESNRD--------------FP------------- 594
Query: 285 IQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFP 344
G++ + +++ KGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFP
Sbjct: 595 ----GLSDDYYGAKNL-KGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFP 649
Query: 345 HKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSV 404
HKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSV
Sbjct: 650 HKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSV 709
Query: 405 RAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDK 464
RAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDK
Sbjct: 710 RAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDK 769
Query: 465 AMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
AMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL
Sbjct: 770 AMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 817
Score = 65.1 bits (157), Expect = 1e-10
Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 8/133 (6%)
Query: 49 KIILHKGSTGLGFNIVGG------EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
+I+L +G++GLGF+I GG D GIF++ I+ GG A + G L D +L VN V+
Sbjct: 131 EIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVD 190
Query: 103 LRNATHEQAAAALKRAGQSVTIVAQYR-PEEYSRFESKIHDLREQMMNSSMSSGSGSLRT 161
+ H +A ALK AG V +V + R P + E + + + S++ G G+
Sbjct: 191 VSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLK-GPKGLGFSIAGGIGNQHI 249
Query: 162 SEKRSLYVRALFD 174
S+Y+ + +
Sbjct: 250 PGDNSIYITKIIE 262
Score = 60.8 bits (146), Expect = 3e-09
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 6/80 (7%)
Query: 49 KIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
++ L KG GLGF+I GG + I+++ I+ GG A G L+ GDR+L+VN N
Sbjct: 226 EVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTN 285
Query: 103 LRNATHEQAAAALKRAGQSV 122
L++ HE+A A+LK V
Sbjct: 286 LQDVRHEEAVASLKNTSDMV 305
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 745 bits (1924), Expect = 0.0
Identities = 366/468 (78%), Positives = 426/468 (91%), Gaps = 3/468 (0%)
Query: 45 REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLR 104
REPRK++LH+GSTGLGFNIVGGEDGEGIF+SFILAGGPADLSGELR+GDRI+SVN V+LR
Sbjct: 462 REPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLR 521
Query: 105 NATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK 164
A+HEQAAAALK AGQ+VTIVAQYRPEEYSRFE+KIHDLREQMMNSS+SSGSGSLRTS+K
Sbjct: 522 AASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQK 581
Query: 165 RSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVI 224
RSLYVRALFDYD+T+DS LPSQGL+F +GDILHVINASDDEWWQAR VTP GES+++GVI
Sbjct: 582 RSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVI 641
Query: 225 PSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESS 284
PSK+RVEKKERARLKTVKF+++T + +S KRKK+ SRKFPFYK+K+ QE+S
Sbjct: 642 PSKRRVEKKERARLKTVKFNSKTR--DKGQSFNDKRKKNL-FSRKFPFYKNKDQSEQETS 698
Query: 285 IQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFP 344
+Q VTSN SDSESS +GQE+ +LSYEPV +QE++Y RPVIILGPMKDR+NDDLISEFP
Sbjct: 699 DADQHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFP 758
Query: 345 HKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSV 404
KFGSCVPHTTRP+RD EVDG+DYHFV SREQMEKDIQ++KFIEAGQ+N++LYGTS+QSV
Sbjct: 759 DKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSV 818
Query: 405 RAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDK 464
R VAE+GKHCILDVSGNAIKRLQ AQLYPI+IFIKPKS+E +MEMN+R T EQA K +++
Sbjct: 819 REVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFER 878
Query: 465 AMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
AMKLEQEF E+FTAIVQGD+LE+IYN++KQIIE+QSG YIWVP+ EKL
Sbjct: 879 AMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPAKEKL 926
Score = 70.1 bits (170), Expect = 5e-12
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 8/136 (5%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDG------EGIFVSFILAGGPADLSGELRRGDRILSVN 99
E +I L +G++GLGF+I GG D IF++ I+ GG A G LR D IL VN
Sbjct: 221 EYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVN 280
Query: 100 GVNLRNATHEQAAAALKRAGQSVTI-VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGS 158
V++R+ TH +A ALK AG V + V + +P E K+ + + S++ G G+
Sbjct: 281 EVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVSEKIMEIKLIK-GPKGLGFSIAGGVGN 339
Query: 159 LRTSEKRSLYVRALFD 174
S+YV + +
Sbjct: 340 QHIPGDNSIYVTKIIE 355
Score = 59.7 bits (143), Expect = 6e-09
Identities = 34/80 (42%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 49 KIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
+I L KG GLGF+I GG + I+V+ I+ GG A G+L+ GD++L+VN V
Sbjct: 319 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVC 378
Query: 103 LRNATHEQAAAALKRAGQSV 122
L THE+A ALK V
Sbjct: 379 LEEVTHEEAVTALKNTSDFV 398
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 739 bits (1907), Expect = 0.0
Identities = 366/467 (78%), Positives = 417/467 (89%), Gaps = 14/467 (2%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRN 105
EPRK++LHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGEL+RGD+ILSVNG++LR
Sbjct: 523 EPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRG 582
Query: 106 ATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKR 165
A+HEQAAAALK AGQ+VTI+AQY+PE+Y+RFE+KIHDLREQMMN SMSSGSGSLRT++KR
Sbjct: 583 ASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKR 642
Query: 166 SLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIP 225
SLYVRA+FDYD+++DS LPSQGLSF YGDILHVINASDDEWWQAR V G+SE++GVIP
Sbjct: 643 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIP 702
Query: 226 SKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSI 285
SK+RVE+KERARLKTVKF+A+ G+I+S S KRKKSF SRKFPFYK+KE QE
Sbjct: 703 SKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQE--- 759
Query: 286 QEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPH 345
TSD E +GQED ILSYEPVTRQEI+Y RPVIILGPMKDR+NDDLISEFP
Sbjct: 760 --------TSDPE---RGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPD 808
Query: 346 KFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVR 405
KFGSCVPHTTRP+RD EVDG+DYHFV+SREQMEKDIQ++KFIEAGQ+NDNLYGTS+QSVR
Sbjct: 809 KFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVR 868
Query: 406 AVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKA 465
VAERGKHCILDVSGNAIKRLQ AQLYPIAIFIKP+S+E LMEMN+R T EQA K YD+A
Sbjct: 869 FVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRA 928
Query: 466 MKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
+KLEQEFGEYFTAIVQGD+LE+IYN+ K +IE+QSG +IW+PS EKL
Sbjct: 929 IKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 975
Score = 68.6 bits (166), Expect = 1e-11
Identities = 48/136 (35%), Positives = 71/136 (52%), Gaps = 8/136 (5%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVN 99
E +I L +G++GLGF+I GG D GIF++ I+ GG A G LR D IL VN
Sbjct: 200 EFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVN 259
Query: 100 GVNLRNATHEQAAAALKRAGQSVTI-VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGS 158
V++ +H +A ALK AG V + V + RP + E K+ + + S++ G G+
Sbjct: 260 EVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFK-GPKGLGFSIAGGVGN 318
Query: 159 LRTSEKRSLYVRALFD 174
S+YV + D
Sbjct: 319 QHIPGDNSIYVTKIID 334
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 12/122 (9%)
Query: 49 KIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
+I L KG GLGF+I GG + I+V+ I+ GG A G L+ GDR+L VN +
Sbjct: 298 EIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYS 357
Query: 103 LRNATHEQAAAALKRAGQSVTI-----VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSG 157
L THE+A A LK + V + Y + Y H M N +S +G
Sbjct: 358 LEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGP-PDITHSYSPPMENHLLSGNNG 416
Query: 158 SL 159
+L
Sbjct: 417 TL 418
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 739 bits (1907), Expect = 0.0
Identities = 366/467 (78%), Positives = 417/467 (89%), Gaps = 14/467 (2%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRN 105
EPRK++LHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGEL+RGD+ILSVNG++LR
Sbjct: 418 EPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRG 477
Query: 106 ATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKR 165
A+HEQAAAALK AGQ+VTI+AQY+PE+Y+RFE+KIHDLREQMMN SMSSGSGSLRT++KR
Sbjct: 478 ASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKR 537
Query: 166 SLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIP 225
SLYVRA+FDYD+++DS LPSQGLSF YGDILHVINASDDEWWQAR V G+SE++GVIP
Sbjct: 538 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIP 597
Query: 226 SKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSI 285
SK+RVE+KERARLKTVKF+A+ G+I+S S KRKKSF SRKFPFYK+KE QE
Sbjct: 598 SKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQE--- 654
Query: 286 QEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPH 345
TSD E +GQED ILSYEPVTRQEI+Y RPVIILGPMKDR+NDDLISEFP
Sbjct: 655 --------TSDPE---RGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPD 703
Query: 346 KFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVR 405
KFGSCVPHTTRP+RD EVDG+DYHFV+SREQMEKDIQ++KFIEAGQ+NDNLYGTS+QSVR
Sbjct: 704 KFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVR 763
Query: 406 AVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKA 465
VAERGKHCILDVSGNAIKRLQ AQLYPIAIFIKP+S+E LMEMN+R T EQA K YD+A
Sbjct: 764 FVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRA 823
Query: 466 MKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
+KLEQEFGEYFTAIVQGD+LE+IYN+ K +IE+QSG +IW+PS EKL
Sbjct: 824 IKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 870
Score = 68.6 bits (166), Expect = 1e-11
Identities = 48/136 (35%), Positives = 71/136 (52%), Gaps = 8/136 (5%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVN 99
E +I L +G++GLGF+I GG D GIF++ I+ GG A G LR D IL VN
Sbjct: 95 EFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVN 154
Query: 100 GVNLRNATHEQAAAALKRAGQSVTI-VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGS 158
V++ +H +A ALK AG V + V + RP + E K+ + + S++ G G+
Sbjct: 155 EVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFK-GPKGLGFSIAGGVGN 213
Query: 159 LRTSEKRSLYVRALFD 174
S+YV + D
Sbjct: 214 QHIPGDNSIYVTKIID 229
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 12/122 (9%)
Query: 49 KIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
+I L KG GLGF+I GG + I+V+ I+ GG A G L+ GDR+L VN +
Sbjct: 193 EIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYS 252
Query: 103 LRNATHEQAAAALKRAGQSVTI-----VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSG 157
L THE+A A LK + V + Y + Y H M N +S +G
Sbjct: 253 LEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGP-PDITHSYSPPMENHLLSGNNG 311
Query: 158 SL 159
+L
Sbjct: 312 TL 313
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 702 bits (1812), Expect = 0.0
Identities = 350/468 (74%), Positives = 406/468 (86%), Gaps = 25/468 (5%)
Query: 45 REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLR 104
REPRK++LH+GSTGLGFNIVGGEDGEGIF+SFILAGGPADLSGELR+GDRI+SVN V+LR
Sbjct: 462 REPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLR 521
Query: 105 NATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK 164
A+HEQAAAALK AGQ+VTIVAQYRPEEYSRFE+KIHDLREQMMNSS+SSGSGSLRTS+K
Sbjct: 522 AASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQK 581
Query: 165 RSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVI 224
RSLYVRALFDYD+T+DS LPSQGL+F +GDILHVINASDDEWWQAR VTP GES+++GVI
Sbjct: 582 RSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVI 641
Query: 225 PSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESS 284
PSK+RVEKKERARLKTVKF+++T R + P + +
Sbjct: 642 PSKRRVEKKERARLKTVKFNSKT-----------------RDKGEIPDDMGSKGLKH--- 681
Query: 285 IQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFP 344
VTSN SDSESS +GQE+ +LSYEPV +QE++Y RPVIILGPMKDR+NDDLISEFP
Sbjct: 682 -----VTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFP 736
Query: 345 HKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSV 404
KFGSCVPHTTRP+RD EVDG+DYHFV SREQMEKDIQ++KFIEAGQ+N++LYGTS+QSV
Sbjct: 737 DKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSV 796
Query: 405 RAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDK 464
R VAE+GKHCILDVSGNAIKRLQ AQLYPI+IFIKPKS+E +MEMN+R T EQA K +++
Sbjct: 797 REVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFER 856
Query: 465 AMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
AMKLEQEF E+FTAIVQGD+LE+IYN++KQIIE+QSG YIWVP+ EKL
Sbjct: 857 AMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPAKEKL 904
Score = 70.1 bits (170), Expect = 5e-12
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 8/136 (5%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDG------EGIFVSFILAGGPADLSGELRRGDRILSVN 99
E +I L +G++GLGF+I GG D IF++ I+ GG A G LR D IL VN
Sbjct: 221 EYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVN 280
Query: 100 GVNLRNATHEQAAAALKRAGQSVTI-VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGS 158
V++R+ TH +A ALK AG V + V + +P E K+ + + S++ G G+
Sbjct: 281 EVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVSEKIMEIKLIK-GPKGLGFSIAGGVGN 339
Query: 159 LRTSEKRSLYVRALFD 174
S+YV + +
Sbjct: 340 QHIPGDNSIYVTKIIE 355
Score = 59.7 bits (143), Expect = 6e-09
Identities = 34/80 (42%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 49 KIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
+I L KG GLGF+I GG + I+V+ I+ GG A G+L+ GD++L+VN V
Sbjct: 319 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVC 378
Query: 103 LRNATHEQAAAALKRAGQSV 122
L THE+A ALK V
Sbjct: 379 LEEVTHEEAVTALKNTSDFV 398
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 693 bits (1788), Expect = 0.0
Identities = 346/467 (74%), Positives = 399/467 (85%), Gaps = 32/467 (6%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRN 105
EPRK++LHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGEL+RGD+ILSVNG++LR
Sbjct: 315 EPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRG 374
Query: 106 ATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKR 165
A+HEQAAAALK AGQ+VTI+AQY+PE+Y+RFE+KIHDLREQMMN SMSSGSGSLRT++KR
Sbjct: 375 ASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKR 434
Query: 166 SLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIP 225
SLYVRA+FDYD+++DS LPSQGLSF YGDILHVINASDDEWWQAR V G+SE++GVIP
Sbjct: 435 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIP 494
Query: 226 SKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSI 285
SK+RVE+KERARLKTVKF+A+ G+I+S I +
Sbjct: 495 SKRRVERKERARLKTVKFNAKPGVIDSKGDIP--------------------------GL 528
Query: 286 QEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPH 345
+ G + T +GQED ILSYEPVTRQEI+Y RPVIILGPMKDR+NDDLISEFP
Sbjct: 529 GDDGYGTKTL------RGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPD 582
Query: 346 KFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVR 405
KFGSCVPHTTRP+RD EVDG+DYHFV+SREQMEKDIQ++KFIEAGQ+NDNLYGTS+QSVR
Sbjct: 583 KFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVR 642
Query: 406 AVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKA 465
VAERGKHCILDVSGNAIKRLQ AQLYPIAIFIKP+S+E LMEMN+R T EQA K YD+A
Sbjct: 643 FVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRA 702
Query: 466 MKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
+KLEQEFGEYFTAIVQGD+LE+IYN+ K +IE+QSG +IW+PS EKL
Sbjct: 703 IKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 749
Score = 68.6 bits (166), Expect = 1e-11
Identities = 48/136 (35%), Positives = 71/136 (52%), Gaps = 8/136 (5%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVN 99
E +I L +G++GLGF+I GG D GIF++ I+ GG A G LR D IL VN
Sbjct: 44 EFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVN 103
Query: 100 GVNLRNATHEQAAAALKRAGQSVTI-VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGS 158
V++ +H +A ALK AG V + V + RP + E K+ + + S++ G G+
Sbjct: 104 EVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFK-GPKGLGFSIAGGVGN 162
Query: 159 LRTSEKRSLYVRALFD 174
S+YV + D
Sbjct: 163 QHIPGDNSIYVTKIID 178
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 12/122 (9%)
Query: 49 KIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
+I L KG GLGF+I GG + I+V+ I+ GG A G L+ GDR+L VN +
Sbjct: 142 EIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYS 201
Query: 103 LRNATHEQAAAALKRAGQSVTI-----VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSG 157
L THE+A A LK + V + Y + Y H M N +S +G
Sbjct: 202 LEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGP-PDITHSYSPPMENHLLSGNNG 260
Query: 158 SL 159
+L
Sbjct: 261 TL 262
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 590 bits (1521), Expect = e-168
Identities = 293/468 (62%), Positives = 364/468 (77%), Gaps = 52/468 (11%)
Query: 45 REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLR 104
REPR+I++H+GSTGLGFNIVGGEDGEGIF+SFILAGGPADLSGELR+GD+ILSVNGV+LR
Sbjct: 352 REPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 411
Query: 105 NATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK 164
NA+HEQAA ALK AGQ+VTI+AQY+PEEYSRFE+KIHDLREQ+MNSS+ SG+ SLR++ K
Sbjct: 412 NASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPK 471
Query: 165 RSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVI 224
R Y+RALFDYD+T+D SQ LSF +GD+LHVI+ASD+EWWQAR V E++ IG I
Sbjct: 472 RGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFI 531
Query: 225 PSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESS 284
PSK+RVE+ R++ K+K+
Sbjct: 532 PSKRRVER-----------------------------------REWSRLKAKD------- 549
Query: 285 IQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFP 344
S S S+G+ED++LSYE VT+ E+HYARP+IILGP KDR NDDL+SEFP
Sbjct: 550 ----------WGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFP 599
Query: 345 HKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSV 404
KFGSCVPHTTRP+R+ E+DG+DYHFV SRE+MEKDIQ +KFIEAGQ+N +LYGTS+QSV
Sbjct: 600 DKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSV 659
Query: 405 RAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDK 464
R VAE+GKHCILDVS NA++RLQ A L+PIAIFI+P+S+E ++E+N+R T EQA K +D+
Sbjct: 660 REVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDR 719
Query: 465 AMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
A KLEQEF E F+AIV+GDS EEIY+K+K++IED SG YIWVP+ E+L
Sbjct: 720 ATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 767
Score = 68.6 bits (166), Expect = 1e-11
Identities = 47/136 (34%), Positives = 69/136 (50%), Gaps = 8/136 (5%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVN 99
E +I L +G++GLGF+I GG D IF++ I+ GG A G LR D IL VN
Sbjct: 105 EYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVN 164
Query: 100 GVNLRNATHEQAAAALKRAGQSVTI-VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGS 158
V++R TH A ALK AG V + V + +P E K+ + + S++ G G+
Sbjct: 165 EVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIK-GPKGLGFSIAGGVGN 223
Query: 159 LRTSEKRSLYVRALFD 174
S+YV + +
Sbjct: 224 QHIPGDNSIYVTKIIE 239
Score = 60.1 bits (144), Expect = 5e-09
Identities = 35/79 (44%), Positives = 46/79 (58%), Gaps = 6/79 (7%)
Query: 44 AREPRKIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILS 97
A + +I L KG GLGF+I GG + I+V+ I+ GG A G L+ GD+IL+
Sbjct: 198 AEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 257
Query: 98 VNGVNLRNATHEQAAAALK 116
VN V L + HE A AALK
Sbjct: 258 VNSVGLEDVMHEDAVAALK 276
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 590 bits (1521), Expect = e-168
Identities = 293/468 (62%), Positives = 364/468 (77%), Gaps = 52/468 (11%)
Query: 45 REPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLR 104
REPR+I++H+GSTGLGFNIVGGEDGEGIF+SFILAGGPADLSGELR+GD+ILSVNGV+LR
Sbjct: 306 REPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 365
Query: 105 NATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK 164
NA+HEQAA ALK AGQ+VTI+AQY+PEEYSRFE+KIHDLREQ+MNSS+ SG+ SLR++ K
Sbjct: 366 NASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPK 425
Query: 165 RSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVI 224
R Y+RALFDYD+T+D SQ LSF +GD+LHVI+ASD+EWWQAR V E++ IG I
Sbjct: 426 RGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFI 485
Query: 225 PSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESS 284
PSK+RVE+ R++ K+K+
Sbjct: 486 PSKRRVER-----------------------------------REWSRLKAKD------- 503
Query: 285 IQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFP 344
S S S+G+ED++LSYE VT+ E+HYARP+IILGP KDR NDDL+SEFP
Sbjct: 504 ----------WGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFP 553
Query: 345 HKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSV 404
KFGSCVPHTTRP+R+ E+DG+DYHFV SRE+MEKDIQ +KFIEAGQ+N +LYGTS+QSV
Sbjct: 554 DKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSV 613
Query: 405 RAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDK 464
R VAE+GKHCILDVS NA++RLQ A L+PIAIFI+P+S+E ++E+N+R T EQA K +D+
Sbjct: 614 REVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDR 673
Query: 465 AMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 512
A KLEQEF E F+AIV+GDS EEIY+K+K++IED SG YIWVP+ E+L
Sbjct: 674 ATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 721
Score = 68.6 bits (166), Expect = 1e-11
Identities = 47/136 (34%), Positives = 69/136 (50%), Gaps = 8/136 (5%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILSVN 99
E +I L +G++GLGF+I GG D IF++ I+ GG A G LR D IL VN
Sbjct: 59 EYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVN 118
Query: 100 GVNLRNATHEQAAAALKRAGQSVTI-VAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGS 158
V++R TH A ALK AG V + V + +P E K+ + + S++ G G+
Sbjct: 119 EVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIK-GPKGLGFSIAGGVGN 177
Query: 159 LRTSEKRSLYVRALFD 174
S+YV + +
Sbjct: 178 QHIPGDNSIYVTKIIE 193
Score = 60.1 bits (144), Expect = 5e-09
Identities = 35/79 (44%), Positives = 46/79 (58%), Gaps = 6/79 (7%)
Query: 44 AREPRKIILHKGSTGLGFNIVGGEDGE------GIFVSFILAGGPADLSGELRRGDRILS 97
A + +I L KG GLGF+I GG + I+V+ I+ GG A G L+ GD+IL+
Sbjct: 152 AEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 211
Query: 98 VNGVNLRNATHEQAAAALK 116
VN V L + HE A AALK
Sbjct: 212 VNSVGLEDVMHEDAVAALK 230
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 516 bits (1328), Expect = e-146
Identities = 260/366 (71%), Positives = 300/366 (81%), Gaps = 32/366 (8%)
Query: 147 MMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEW 206
MMN SMSSGSGSLRT++KRSLYVRA+FDYD+++DS LPSQGLSF YGDILHVINASDDEW
Sbjct: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
Query: 207 WQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRL 266
WQAR V G+SE++GVIPSK+RVE+KERARLKTVKF+A+ G+I+S I
Sbjct: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIP--------- 111
Query: 267 SRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVI 326
+ + G + T +GQED ILSYEPVTRQEI+Y RPVI
Sbjct: 112 -----------------GLGDDGYGTKTL------RGQEDLILSYEPVTRQEINYTRPVI 148
Query: 327 ILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKF 386
ILGPMKDR+NDDLISEFP KFGSCVPHTTRP+RD EVDG+DYHFV+SREQMEKDIQ++KF
Sbjct: 149 ILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKF 208
Query: 387 IEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEAL 446
IEAGQ+NDNLYGTS+QSVR VAERGKHCILDVSGNAIKRLQ AQLYPIAIFIKP+S+E L
Sbjct: 209 IEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPL 268
Query: 447 MEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWV 506
MEMN+R T EQA K YD+A+KLEQEFGEYFTAIVQGD+LE+IYN+ K +IE+QSG +IW+
Sbjct: 269 MEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWI 328
Query: 507 PSPEKL 512
PS EKL
Sbjct: 329 PSKEKL 334
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 201 bits (512), Expect = 1e-51
Identities = 137/450 (30%), Positives = 213/450 (47%), Gaps = 65/450 (14%)
Query: 70 EGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYR 129
+ + +S I+ GG A+ SG L GD +L +NG+ +R + L ++T V
Sbjct: 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL--- 332
Query: 130 PEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--G 187
+ S +++ ++V+A FDYD + D +P + G
Sbjct: 333 ----------------------IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG 370
Query: 188 LSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERAR--LKTVKFHA 245
LSF GDILHVI+ D WWQA G++P K +++E + ++ K
Sbjct: 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPE 430
Query: 246 RTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQE 305
++G + + K KRKK + K Y ++E + E
Sbjct: 431 KSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYE----------------------- 467
Query: 306 DAILSYEPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNE 362
+ L ++P R+ RP+I++GP ++ + L+++ +F S VPHTTR RRD E
Sbjct: 468 EMSLYHQPANRK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
Query: 363 VDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNA 422
V G+DYHFV SR+ E DI KFIE G+F NLYGTSI SVR V GK C+L + +
Sbjct: 523 VAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
Query: 423 IKRLQQAQLYPIAIFIKPKSIEALMEM----NRRQTYEQANKIYDKAMKLEQEFGEYFTA 478
+K L+ + L P IFI P S E L + + E+ +I +K ++EQ G YF
Sbjct: 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDT 641
Query: 479 IVQGDSLEEIYNKIKQIIEDQSGHYIWVPS 508
+ L++ Y ++ ++I WVPS
Sbjct: 642 AIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
>gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]
Length = 576
Score = 196 bits (498), Expect = 4e-50
Identities = 155/492 (31%), Positives = 226/492 (45%), Gaps = 80/492 (16%)
Query: 43 DAREPRKII-LHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGV 101
D + KII L K LG I E I V+ I+ GG AD SG + GD + VNG+
Sbjct: 132 DEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGI 191
Query: 102 NLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRT 161
+ + E+ L ++ ++T + GS
Sbjct: 192 PVEDKRPEEIIQILAQSQGAITF--------------------------KIIPGSKEETP 225
Query: 162 SEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESE 219
S++ ++++ALFDY+ D +P + GLSF GDIL +++ D WWQA+ +
Sbjct: 226 SKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEAD--ANP 283
Query: 220 QIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENM 279
+ G+IPSK E++ R + + SNR RK SFRLSRK
Sbjct: 284 RAGLIPSKHFQERRLALRRPEILVQP---LKVSNRKSSGFRK-SFRLSRK---------- 329
Query: 280 AQESSIQEQGVTSNTSDSESSSKGQEDA--ILSYEPVT---RQEIHYARPVIILGPMKDR 334
+N S E Q D + +YE VT RQ R V+++GP+
Sbjct: 330 ---------DKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVG 380
Query: 335 VNDD----LISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAG 390
+N+ LIS+ H +G VPHTTR RR E DG +Y F+ S+ E D+Q+NKFIE G
Sbjct: 381 LNELKRKLLISDTQH-YGVTVPHTTRARRSQESDGVEYIFI-SKHLFETDVQNNKFIEYG 438
Query: 391 QFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMN 450
++ +N YGTSI SVR+V + K C+LDV + +K L+ + P IFIKP SIE L E
Sbjct: 439 EYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETR 498
Query: 451 RRQ---------------TYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQI 495
+ T E ++ A +E ++G F I+ D L +N++K
Sbjct: 499 KNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTT 558
Query: 496 IEDQSGHYIWVP 507
+ WVP
Sbjct: 559 FDKLETETHWVP 570
>gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
Length = 585
Score = 180 bits (457), Expect = 2e-45
Identities = 136/499 (27%), Positives = 235/499 (47%), Gaps = 83/499 (16%)
Query: 43 DAREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
D + + L K LG I E + V+ I+ GG AD SG + GD + VNG+
Sbjct: 131 DEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIA 190
Query: 103 LRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRF-ESKIHDLREQMMNSSMSSGSGSLRT 161
+ + ++ + L ++ S+T+ +E R ESK+
Sbjct: 191 VLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKV--------------------- 229
Query: 162 SEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESE 219
++RALF Y+ D +P Q GL F +L V++ D WWQA+ V G++
Sbjct: 230 ------FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---GDTN 280
Query: 220 -QIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYK--SK 276
+ G+IPSK E++ + + G + S +S+ RK P+ + K
Sbjct: 281 LRAGLIPSKGFQERR-------LSYRRAAGTLPSPQSL-----------RKPPYDQPCDK 322
Query: 277 ENMAQESSIQEQGVTS--------------NTSDSESSSKGQEDAILSYEPVTR---QEI 319
E E ++ V + + + SS + +L+YE V R Q
Sbjct: 323 ETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPG 382
Query: 320 HYARPVIILGPMKDRVND---DLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQ 376
R V+++G + R+++ +++E P FG VPHTTRPR+ +E +G +YHFV S++
Sbjct: 383 ERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQA 441
Query: 377 MEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAI 436
E D+ NKF+E G++ +NLYGTS+++++AV + K C++DV A+K+L+ ++ P I
Sbjct: 442 FEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYII 501
Query: 437 FIKP--------KSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEI 488
F+KP + E EQ ++ A +++ +G A++ + L+
Sbjct: 502 FVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGA 561
Query: 489 YNKIKQIIEDQSGHYIWVP 507
Y+++K ++E S WVP
Sbjct: 562 YSQLKVVLEKLSKDTHWVP 580
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 172 bits (435), Expect = 9e-43
Identities = 132/486 (27%), Positives = 229/486 (47%), Gaps = 69/486 (14%)
Query: 37 SLRPGGDAR----EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRG 92
S R GDA EPR + + K LG ++ GG + G+FV+ + PA L G
Sbjct: 1486 SSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGG-NLHGVFVAEVEDDSPAKGPDGLVPG 1544
Query: 93 DRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSM 152
D IL +++RN T E+ + + V + QYRPEE+++ + D
Sbjct: 1545 DLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGD---------- 1594
Query: 153 SSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEW---WQA 209
S Y+RAL YDR D Q LSF DIL+V + W A
Sbjct: 1595 -------------SFYIRAL--YDRLADV---EQELSFKKDDILYVDDTLPQGTFGSWMA 1636
Query: 210 RLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRK 269
+ + + Q G IPSK ++++ RL + + + + N + KT + R
Sbjct: 1637 WQLDENAQKIQRGQIPSKYVMDQEFSRRL------SMSEVKDDNSATKTLSAAARR---- 1686
Query: 270 FPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAI-LSYEPVTRQEIHYARPVIIL 328
F++ K + S + + + + S S ED++ L+Y+ V + + RPV+IL
Sbjct: 1687 -SFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLIL 1745
Query: 329 GPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIE 388
GP+ D V + L++E P KF C + S++ +E+ ++D F++
Sbjct: 1746 GPLLDVVKEMLVNEAPGKFCRCPLEVMK---------------ASQQAIERGVKDCLFVD 1790
Query: 389 AGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALME 448
+ + + T++ S++ + E+ +HC+LD++ +AI+RL +YPI IFI KS + + E
Sbjct: 1791 YKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKE 1850
Query: 449 ------MNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGH 502
+ + T + + ++ A KLEQE+ YFT ++QG +L I +I ++ +
Sbjct: 1851 QRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNK 1910
Query: 503 YIWVPS 508
+W+P+
Sbjct: 1911 VLWIPA 1916
Score = 73.2 bits (178), Expect = 5e-13
Identities = 45/116 (38%), Positives = 65/116 (56%), Gaps = 10/116 (8%)
Query: 46 EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRN 105
EPR + + KGS LG +IV GE G GI+VS + G A +G L GD++L NG+NLR+
Sbjct: 1347 EPRHVKVQKGSEPLGISIVSGEKG-GIYVSKVTVGSIAHQAG-LEYGDQLLEFNGINLRS 1404
Query: 106 ATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRT 161
AT +QA + + ++TI+AQY P +H L +SS +G+ T
Sbjct: 1405 ATEQQARLIIGQQCDTITILAQYNPH--------VHQLSSHSRSSSHLDPAGTHST 1452
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 5/82 (6%)
Query: 48 RKIILHKGSTGLGFNIVGGEDG-----EGIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
RK + K T L N+ G +D G++ + +L G PA G L GDRI+++NG+
Sbjct: 709 RKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIA 768
Query: 103 LRNATHEQAAAALKRAGQSVTI 124
L N + + + L+ S+T+
Sbjct: 769 LDNKSLNECESLLRSCQDSLTL 790
>gi|52630447 palmitoylated membrane protein 2 [Homo sapiens]
Length = 552
Score = 166 bits (421), Expect = 4e-41
Identities = 126/469 (26%), Positives = 214/469 (45%), Gaps = 92/469 (19%)
Query: 58 GLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKR 117
G+ F + GGE + ++ IL GG G L GD I VNG Q + R
Sbjct: 152 GVTFRVEGGE----LVIARILHGGMVAQQGLLHVGDIIKEVNG---------QPVGSDPR 198
Query: 118 AGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEK----RSLYVRALF 173
A L+E + N+S S L + ++ R ++V+ F
Sbjct: 199 A------------------------LQELLRNASGSVILKILPSYQEPHLPRQVFVKCHF 234
Query: 174 DYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVE 231
DYD RDS +P + GL F+ GD+L ++N D WWQA H E G+IPS+ E
Sbjct: 235 DYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQAC----HVEGGSAGLIPSQLLEE 290
Query: 232 KKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVT 291
K++ + ++ +G + + S K K++ + ++ F + +
Sbjct: 291 KRKAFVKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHE--------------- 335
Query: 292 SNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFG 348
+L YE V R + ++++G + + + LI P ++G
Sbjct: 336 ----------------LLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYG 379
Query: 349 SCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVA 408
+ VP+T+R +D+E +GQ Y FV SR +ME D++ +++E G++ NLYGT I S+R V
Sbjct: 380 TTVPYTSRRPKDSEREGQGYSFV-SRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVV 438
Query: 409 ERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNR----------RQTYEQA 458
GK C+LDV+ A+K L+ A+ P +FI+ E L MNR + T
Sbjct: 439 AAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGISTKQLTEADL 498
Query: 459 NKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVP 507
+ +++ ++++ +G YF + +LE + +++ +E WVP
Sbjct: 499 RRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVP 547
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 164 bits (414), Expect = 2e-40
Identities = 118/446 (26%), Positives = 210/446 (47%), Gaps = 56/446 (12%)
Query: 74 VSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVT--IVAQYRPE 131
V+ I+ GG G L GD I +NG+++ N T EQ L+ S+T IV YR +
Sbjct: 515 VARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQ 574
Query: 132 EYSRFESKIHDLREQMMNSSMSSGSG-----SLRTSEKRSLYVRALFDYDRTRDSCLPSQ 186
S R+ N S+ + S + R +YVRA F+YD +D +P +
Sbjct: 575 SSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCK 634
Query: 187 --GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFH 244
G+ F GDI+ +I+ D WWQ +L + ++ G+IPS + E
Sbjct: 635 EAGIRFRVGDIIQIISKDDHNWWQGKL--ENSKNGTAGLIPSPELQEW------------ 680
Query: 245 ARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQ 304
R I ++ + ++ +K YK K + + +D
Sbjct: 681 -RVACIAMEKTKQEQQASCTWFGKKKKQYKDKY------------LAKHNAD-------- 719
Query: 305 EDAILSYEPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDN 361
+++YE V + + +++LG + + + LI++ P +F +PHTTRP + +
Sbjct: 720 ---LVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKD 776
Query: 362 EVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGN 421
E +G++Y+FV S +QM +DI +N+++E G D +YGT ++++R + E+G ILDV
Sbjct: 777 EENGKNYYFV-SHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQ 835
Query: 422 AIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQ 481
A+K L+ A+ P +FI +I +N ++ ++ K D L++ + YF +
Sbjct: 836 ALKVLRTAEFAPFVVFIAAPTITP--GLNEDESLQRLQKESD---ILQRTYAHYFDLTII 890
Query: 482 GDSLEEIYNKIKQIIEDQSGHYIWVP 507
+ ++E +++ +E WVP
Sbjct: 891 NNEIDETIRHLEEAVELVCTAPQWVP 916
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 160 bits (406), Expect = 2e-39
Identities = 117/441 (26%), Positives = 212/441 (48%), Gaps = 64/441 (14%)
Query: 74 VSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVT--IVAQYRPE 131
V+ I+ GG G L GD I +NG+++ N T EQ L+ S+T IV YR +
Sbjct: 509 VARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQ 568
Query: 132 EYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--GLS 189
S E + +++ G R +YVRA F+YD +D +P + G+
Sbjct: 569 SSSC---------EDLPSTTQPKG---------RQIYVRAQFEYDPAKDDLIPCKEAGIR 610
Query: 190 FSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGM 249
F GDI+ +I+ D WWQ +L + ++ G+IPS + E R
Sbjct: 611 FRVGDIIQIISKDDHNWWQGKL--ENSKNGTAGLIPSPELQEW-------------RVAC 655
Query: 250 IESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAIL 309
I ++ + ++ +K YK K +A+ +++ +Q ++
Sbjct: 656 IAMEKTKQEQQASCTWFGKKKKQYKDKY-LAKHNAVFDQL-----------------DLV 697
Query: 310 SYEPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQ 366
+YE V + + +++LG + + + LI++ P +F +PHTTRP + +E +G+
Sbjct: 698 TYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGK 757
Query: 367 DYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRL 426
+Y+FV S +QM +DI +N+++E G D +YGT ++++R + E+G ILDV A+K L
Sbjct: 758 NYYFV-SHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVL 816
Query: 427 QQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLE 486
+ A+ P +FI +I +N ++ ++ K D L++ + YF + + ++
Sbjct: 817 RTAEFAPFVVFIAAPTITP--GLNEDESLQRLQKESD---ILQRTYAHYFDLTIINNEID 871
Query: 487 EIYNKIKQIIEDQSGHYIWVP 507
E +++ +E WVP
Sbjct: 872 ETIRHLEEAVELVCTAPQWVP 892
>gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]
Length = 466
Score = 159 bits (402), Expect = 6e-39
Identities = 116/439 (26%), Positives = 202/439 (46%), Gaps = 78/439 (17%)
Query: 74 VSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEY 133
V+ IL GG G L GD IL +NG N+ N + +Q A+K +++ + P +
Sbjct: 96 VARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKGMISL--KVIPNQQ 153
Query: 134 SRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--GLSFS 191
SR + +++RA FDYD +D+ +P + GL F+
Sbjct: 154 SRLPA--------------------------LQMFMRAQFDYDPKKDNLIPCKEAGLKFA 187
Query: 192 YGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIE 251
GDI+ +IN D WWQ R+ E G+IPS + E + + ++ A
Sbjct: 188 TGDIIQIINKDDSNWWQGRV--EGSSKESAGLIPSPELQEWRVASMAQSAPSEA------ 239
Query: 252 SNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSY 311
+ S K+KK YK K +A+ SSI +Q ++SY
Sbjct: 240 PSCSPFGKKKK----------YKDK-YLAKHSSIFDQ-----------------LDVVSY 271
Query: 312 EPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDY 368
E V R + ++++G + + + L+S+ P KF VP+TTRP R +E DG++Y
Sbjct: 272 EEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEY 331
Query: 369 HFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQ 428
HF +S E+M ++I N+F+E G + N++GT ++V + ++ K ILD+ +K ++
Sbjct: 332 HF-ISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVRT 390
Query: 429 AQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEI 488
A+L P +FI P ++ E ++ + + ++ YF + + ++E
Sbjct: 391 AELSPFIVFIAP--------TDQGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDET 442
Query: 489 YNKIKQIIEDQSGHYIWVP 507
K+++ + WVP
Sbjct: 443 LKKLQEAFDQACSSPQWVP 461
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 158 bits (400), Expect = 1e-38
Identities = 116/441 (26%), Positives = 208/441 (47%), Gaps = 69/441 (15%)
Query: 74 VSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVT--IVAQYRPE 131
V+ I+ GG G L GD I +NG+++ N T EQ L+ S+T IV YR +
Sbjct: 515 VARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQ 574
Query: 132 EYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--GLS 189
S E + +++ G R +YVRA F+YD +D +P + G+
Sbjct: 575 SSSC---------EDLPSTTQPKG---------RQIYVRAQFEYDPAKDDLIPCKEAGIR 616
Query: 190 FSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGM 249
F GDI+ +I+ D WWQ +L + ++ G+IPS + E R
Sbjct: 617 FRVGDIIQIISKDDHNWWQGKL--ENSKNGTAGLIPSPELQEW-------------RVAC 661
Query: 250 IESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAIL 309
I ++ + ++ +K YK K + + +D ++
Sbjct: 662 IAMEKTKQEQQASCTWFGKKKKQYKDKY------------LAKHNAD-----------LV 698
Query: 310 SYEPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQ 366
+YE V + + +++LG + + + LI++ P +F +PHTTRP + +E +G+
Sbjct: 699 TYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGK 758
Query: 367 DYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRL 426
+Y+FV S +QM +DI +N+++E G D +YGT ++++R + E+G ILDV A+K L
Sbjct: 759 NYYFV-SHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVL 817
Query: 427 QQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLE 486
+ A+ P +FI +I +N ++ ++ K D L++ + YF + + ++
Sbjct: 818 RTAEFAPFVVFIAAPTITP--GLNEDESLQRLQKESD---ILQRTYAHYFDLTIINNEID 872
Query: 487 EIYNKIKQIIEDQSGHYIWVP 507
E +++ +E WVP
Sbjct: 873 ETIRHLEEAVELVCTAPQWVP 893
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 158 bits (400), Expect = 1e-38
Identities = 126/457 (27%), Positives = 204/457 (44%), Gaps = 86/457 (18%)
Query: 68 DGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVT--IV 125
+ + ++ IL GG D G L GD I VNG + N E LK SVT I+
Sbjct: 148 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNNPKE-LQELLKNISGSVTLKIL 206
Query: 126 AQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPS 185
YR T + ++V+ FDY+ D+ +P
Sbjct: 207 PSYRD------------------------------TITPQQVFVKCHFDYNPYNDNLIPC 236
Query: 186 Q--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKF 243
+ GL FS G+IL ++N D WWQA V G + G+IPS+ +E+K +A ++ +
Sbjct: 237 KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---GLIPSQF-LEEKRKAFVR--RD 290
Query: 244 HARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKG 303
+G S K K+K + +R F + +
Sbjct: 291 WDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHE--------------------------- 323
Query: 304 QEDAILSYEPVTRQEIHYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRD 360
I YE V + + ++++G + + + I P +FG+ VP T+R R+
Sbjct: 324 ----IQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPRE 379
Query: 361 NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG 420
+E DGQ Y FV SR +ME DI+ K++E G++ NLYGT I S+ V + G+ CILDV+
Sbjct: 380 DEKDGQAYKFV-SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNP 438
Query: 421 NAIKRLQQAQLYPIAIFIKPKSIEALMEMNRR----------QTYEQANKIYDKAMKLEQ 470
A+K L+ ++ P +FI +E L M++ T K D++ ++++
Sbjct: 439 QALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQR 498
Query: 471 EFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVP 507
+ YF I+ D+L++ + K++ IE WVP
Sbjct: 499 AYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVP 535
>gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens]
Length = 637
Score = 154 bits (390), Expect = 1e-37
Identities = 127/511 (24%), Positives = 227/511 (44%), Gaps = 86/511 (16%)
Query: 48 RKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNAT 107
R + L K LG I E I V+ I+ GG A+ SG L GD+++ VNGV++
Sbjct: 153 RIVCLVKNQQPLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLD 212
Query: 108 HEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSL 167
EQ L + ++ K+ + + +NS ++ +
Sbjct: 213 PEQVIHILAMSRGTIMF--------------KVVPVSDPPVNS-------------QQMV 245
Query: 168 YVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIP 225
YVRA+ +Y D +P GL F GDIL +++ +D WWQAR ++ G++P
Sbjct: 246 YVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDPATCA--GLVP 303
Query: 226 SKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFP-------------- 271
S +++K+R + + T ++S SI + + ++ K
Sbjct: 304 SNHLLKRKQREFWWSQPYQPHT-CLKSTLSISMEEEDDMKIDEKCVEADEETFESEELSE 362
Query: 272 ----------------FYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVT 315
F +S ++S + + + S S+ G YE V
Sbjct: 363 DKEEFVGYGQKFFIAGFRRSMRLCRRKSHLSPLHASVCCTGSCYSAVGAP-----YEEVV 417
Query: 316 RQEIHYA---RPVIILGPMKDRVND---DLISEFPHKFGSCVPHTTRPRRDNEVDGQDYH 369
R + + R ++++GP VN+ LI P F S VPHTTR ++ E++G++YH
Sbjct: 418 RYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMNGREYH 477
Query: 370 FVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQA 429
+V S+E E I ++ +E G++ +LYGTS+ +V+ V GK C++D+ I+ ++
Sbjct: 478 YV-SKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQGVRTH 536
Query: 430 QLYPIAIFIKPKSIEALMEMNRRQTY------------EQANKIYDKAMKLEQEFGEYFT 477
+L P IFIKP ++ + + + E ++ + A ++E +FG++F
Sbjct: 537 ELKPYVIFIKPSNMRCMKQSRKNAKVITDYYVDMKFKDEDLQEMENLAQRMETQFGQFFD 596
Query: 478 AIVQGDSLEEIYNKIKQIIEDQSGHYIWVPS 508
++ DSL + ++ I+ WVP+
Sbjct: 597 HVIVNDSLHDACAQLLSAIQKAQEEPQWVPA 627
>gi|10092691 tight junction protein 3 [Homo sapiens]
Length = 952
Score = 129 bits (325), Expect = 5e-30
Identities = 128/490 (26%), Positives = 211/490 (43%), Gaps = 110/490 (22%)
Query: 36 RSLRPGGDAREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRI 95
+S+ G + + R + KG + +G + GG D GIFVS + AG PAD G ++ GD+I
Sbjct: 403 QSMEDRGYSPDTRVVRFLKGKS-IGLRLAGGND-VGIFVSGVQAGSPADGQG-IQEGDQI 459
Query: 96 LSVNGVNLRNATHEQAAAALKRA--GQSVTIVAQYRPEEYSRF-ESKIHDLREQMMNSSM 152
L VN V +N T E+A L G+ + +V Q + + + + +S++ D
Sbjct: 460 LQVNDVPFQNLTREEAVQFLLGLPPGEEMELVTQRKQDIFWKMVQSRVGD---------- 509
Query: 153 SSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVIN----------AS 202
S Y+R F+ + + P GL F+ GD+ HV++ A
Sbjct: 510 -------------SFYIRTHFELEPS-----PPSGLGFTRGDVFHVLDTLHPGPGQSHAR 551
Query: 203 DDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTG---MIESNRSIKTK 259
W R+ E E+ G+IP++ R E + A L+ + G SN +
Sbjct: 552 GGHWLAVRMGRDLREQER-GIIPNQSRAE--QLASLEAAQRAVGVGPGSSAGSNARAEFW 608
Query: 260 RKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEI 319
R + R K +S+E++ S++ QG YE V +E
Sbjct: 609 RLRGLRRGAKKTTQRSREDL---SALTRQG-----------------RYPPYERVVLREA 648
Query: 320 HYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEK 379
+ RPV+ILGP+ D L +E P +F E+ E + +
Sbjct: 649 SFKRPVVILGPVADIAMQKLTAEMPDQF--------------EI----------AETVSR 684
Query: 380 DIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIK 439
+K I+ + +VR +AE+ KH +LDV+ +AI+RL Q YPI +F
Sbjct: 685 TDSPSKIIK------------LDTVRVIAEKDKHALLDVTPSAIERLNYVQYYPIVVFFI 732
Query: 440 PKS---IEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEI-YNKIKQI 495
P+S ++AL + + ++Y +A KL + FTA + + + Y ++K I
Sbjct: 733 PESRPALKALRQWLAPASRRSTRRLYAQAQKLRKHSSHLFTATIPLNGTSDTWYQELKAI 792
Query: 496 IEDQSGHYIW 505
I +Q IW
Sbjct: 793 IREQQTRPIW 802
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/72 (40%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 58 GLGFNIVGGED--GEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAAL 115
G G I GG D G + VS ++ GGPA+ G L+ GD I+ VNGV++ NAT A L
Sbjct: 40 GFGIAISGGRDRPGGSMVVSDVVPGGPAE--GRLQTGDHIVMVNGVSMENATSAFAIQIL 97
Query: 116 KRAGQSVTIVAQ 127
K + I +
Sbjct: 98 KTCTKMANITVK 109
Score = 29.3 bits (64), Expect = 8.9
Identities = 15/57 (26%), Positives = 29/57 (50%)
Query: 69 GEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIV 125
G IF+ I G A L+ GD IL +NGV+ +N + ++++ ++++
Sbjct: 230 GSQIFIKHITDSGLAARHRGLQEGDLILQINGVSSQNLSLNDTRRLIEKSEGKLSLL 286
>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
Length = 1668
Score = 128 bits (322), Expect = 1e-29
Identities = 122/489 (24%), Positives = 200/489 (40%), Gaps = 118/489 (24%)
Query: 37 SLRPGGDAREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRIL 96
S G R K++ + +G + GG D GIFV+ +L PA G L GD+IL
Sbjct: 411 STHEDGILRPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQIL 468
Query: 97 SVNGVNLRNATHEQAAAAL--KRAGQSVTIVAQYRPEEYSRF-ESKIHDLREQMMNSSMS 153
VN V+ N E+A L G+ VTI+AQ + + Y R ES + D
Sbjct: 469 RVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGD----------- 517
Query: 154 SGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVI----NASDDEWWQA 209
S Y+R F+Y++ GLSF+ G++ V+ N W
Sbjct: 518 ------------SFYIRTHFEYEKE-----SPYGLSFNKGEVFRVVDTLYNGKLGSWLAI 560
Query: 210 RLVTPHGESEQIGVIPSKKRVEKKERARLKTVK--------FHARTGMIESNRSIKTKRK 261
R+ H E E+ G+IP+K R E+ + K F G+ S R+++
Sbjct: 561 RIGKNHKEVER-GIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLR---- 615
Query: 262 KSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHY 321
KS+E++ S++ + +YE V +E +
Sbjct: 616 ------------KSREDL--------------------SAQPVQTKFPAYERVVLREAGF 643
Query: 322 ARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDI 381
RPV I GP+ D + L E P D + + E
Sbjct: 644 LRPVTIFGPIADVAREKLAREEP----------------------DIYQIAKSEPR---- 677
Query: 382 QDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPK 441
+AG + + +++ + ++ KH +LDV+ NA+ RL AQ YPI +F+ P
Sbjct: 678 ------DAGTDQRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPD 731
Query: 442 SIEALMEMNRR---QTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEE-IYNKIKQIIE 497
S + + M R ++ + A K+Y+++ KL + FT + +S+ + Y +K+ I+
Sbjct: 732 SKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQ 791
Query: 498 DQSGHYIWV 506
Q +WV
Sbjct: 792 QQQNQLVWV 800
Score = 51.6 bits (122), Expect = 2e-06
Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 26/123 (21%)
Query: 46 EPRKIILHKG-STGLGFNIVGGED------GE-GIFVSFILAGGPADLSGELRRGDRILS 97
E + LH+ G G I GG D GE I +S +L GGPA+ G+L+ DR+
Sbjct: 20 EQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAM 77
Query: 98 VNGVNLRNATHEQAAAALKRAGQSVTI-----------VAQYRPE-----EYSRFESKIH 141
VNGV++ N H A L+++G++ I V++ PE E ++ +IH
Sbjct: 78 VNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPDPEPVSDNEEDSYDEEIH 137
Query: 142 DLR 144
D R
Sbjct: 138 DPR 140
Score = 32.3 bits (72), Expect = 1.1
Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 13/126 (10%)
Query: 10 SGLAMGLGSASASAWRRASQRWAWPLRSLRPGGDAR--------EPRKIILHKGSTGLGF 61
SG + + S W R R A RSL P D R +P K+ L K +
Sbjct: 141 SGRSGVVNRRSEKIWPR--DRSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEY 198
Query: 62 NIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQS 121
+ IFV I A G ++ GD +L +NG N + A ++R+
Sbjct: 199 GL---RLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGK 255
Query: 122 VTIVAQ 127
+ +V Q
Sbjct: 256 LKMVVQ 261
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 128 bits (322), Expect = 1e-29
Identities = 122/489 (24%), Positives = 200/489 (40%), Gaps = 118/489 (24%)
Query: 37 SLRPGGDAREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRIL 96
S G R K++ + +G + GG D GIFV+ +L PA G L GD+IL
Sbjct: 411 STHEDGILRPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQIL 468
Query: 97 SVNGVNLRNATHEQAAAAL--KRAGQSVTIVAQYRPEEYSRF-ESKIHDLREQMMNSSMS 153
VN V+ N E+A L G+ VTI+AQ + + Y R ES + D
Sbjct: 469 RVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGD----------- 517
Query: 154 SGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVI----NASDDEWWQA 209
S Y+R F+Y++ GLSF+ G++ V+ N W
Sbjct: 518 ------------SFYIRTHFEYEKE-----SPYGLSFNKGEVFRVVDTLYNGKLGSWLAI 560
Query: 210 RLVTPHGESEQIGVIPSKKRVEKKERARLKTVK--------FHARTGMIESNRSIKTKRK 261
R+ H E E+ G+IP+K R E+ + K F G+ S R+++
Sbjct: 561 RIGKNHKEVER-GIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLR---- 615
Query: 262 KSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHY 321
KS+E++ S++ + +YE V +E +
Sbjct: 616 ------------KSREDL--------------------SAQPVQTKFPAYERVVLREAGF 643
Query: 322 ARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDI 381
RPV I GP+ D + L E P D + + E
Sbjct: 644 LRPVTIFGPIADVAREKLAREEP----------------------DIYQIAKSEPR---- 677
Query: 382 QDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPK 441
+AG + + +++ + ++ KH +LDV+ NA+ RL AQ YPI +F+ P
Sbjct: 678 ------DAGTDQRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPD 731
Query: 442 SIEALMEMNRR---QTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEE-IYNKIKQIIE 497
S + + M R ++ + A K+Y+++ KL + FT + +S+ + Y +K+ I+
Sbjct: 732 SKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQ 791
Query: 498 DQSGHYIWV 506
Q +WV
Sbjct: 792 QQQNQLVWV 800
Score = 51.6 bits (122), Expect = 2e-06
Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 26/123 (21%)
Query: 46 EPRKIILHKG-STGLGFNIVGGED------GE-GIFVSFILAGGPADLSGELRRGDRILS 97
E + LH+ G G I GG D GE I +S +L GGPA+ G+L+ DR+
Sbjct: 20 EQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAM 77
Query: 98 VNGVNLRNATHEQAAAALKRAGQSVTI-----------VAQYRPE-----EYSRFESKIH 141
VNGV++ N H A L+++G++ I V++ PE E ++ +IH
Sbjct: 78 VNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPDPEPVSDNEEDSYDEEIH 137
Query: 142 DLR 144
D R
Sbjct: 138 DPR 140
Score = 32.3 bits (72), Expect = 1.1
Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 13/126 (10%)
Query: 10 SGLAMGLGSASASAWRRASQRWAWPLRSLRPGGDAR--------EPRKIILHKGSTGLGF 61
SG + + S W R R A RSL P D R +P K+ L K +
Sbjct: 141 SGRSGVVNRRSEKIWPR--DRSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEY 198
Query: 62 NIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQS 121
+ IFV I A G ++ GD +L +NG N + A ++R+
Sbjct: 199 GL---RLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGK 255
Query: 122 VTIVAQ 127
+ +V Q
Sbjct: 256 LKMVVQ 261
>gi|42518065 tight junction protein 2 (zona occludens 2) isoform 2
[Homo sapiens]
Length = 1043
Score = 112 bits (279), Expect = 1e-24
Identities = 121/490 (24%), Positives = 196/490 (40%), Gaps = 99/490 (20%)
Query: 27 ASQRWAWPLRSLRPGGDARE----PRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGP 82
A Q A P LRP + K++ K +G + GG D GIFV+ I G
Sbjct: 485 APQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND-VGIFVAGIQEGTS 543
Query: 83 ADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRA--GQSVTIVAQYRPEEYSRFESKI 140
A+ G L+ GD+IL VN + R E A L G+ VTI+AQ R + Y
Sbjct: 544 AEQEG-LQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVY------- 595
Query: 141 HDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVIN 200
++ G G S ++R+ F+ ++ Q L+F+ G++ V++
Sbjct: 596 --------RDILACGRGD-------SFFIRSHFECEKETP-----QSLAFTRGEVFRVVD 635
Query: 201 ASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKR 260
D L G + G+IP+K R E+ + R ++
Sbjct: 636 TLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGV 695
Query: 261 KKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIH 320
KK+ R KS+E++ S+ + +YE V +E
Sbjct: 696 KKNLR--------KSREDLTAVVSVSTK-------------------FPAYERVLLREAG 728
Query: 321 YARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKD 380
+ RPV++ GP+ D + L +E P F + T P KD
Sbjct: 729 FKRPVVLFGPIADIAMEKLANELPDWFQTA---KTEP---------------------KD 764
Query: 381 IQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKP 440
K + N +VR + E+ KH +LDV+ A+ L Q +PI IF P
Sbjct: 765 AGSEKSTGVVRLN---------TVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNP 815
Query: 441 KSIEALMEMNRR---QTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEI-YNKIKQII 496
S + + M +R + + + K++D+A KL++ FTA + +S + + +K I
Sbjct: 816 DSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTATINLNSANDSWFGSLKDTI 875
Query: 497 EDQSGHYIWV 506
+ Q G +WV
Sbjct: 876 QHQQGEAVWV 885
Score = 47.4 bits (111), Expect = 3e-05
Identities = 34/95 (35%), Positives = 49/95 (51%), Gaps = 11/95 (11%)
Query: 46 EPRKIILHKGST-GLGFNIVGGED------GE-GIFVSFILAGGPADLSGELRRGDRILS 97
E + L K S G G + GG D GE I +S +L GGPAD G L+ DR++
Sbjct: 30 EQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPAD--GLLQENDRVVM 87
Query: 98 VNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEE 132
VNG + + H A L+++G+ IV + RP +
Sbjct: 88 VNGTPMEDVLHSFAVQQLRKSGKVAAIVVK-RPRK 121
Score = 32.3 bits (72), Expect = 1.1
Identities = 26/108 (24%), Positives = 44/108 (40%), Gaps = 4/108 (3%)
Query: 69 GEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQY 128
G IFV + G A G L GD IL +NG N + A ++++ + +V
Sbjct: 324 GSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLR 383
Query: 129 RPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYD 176
++ ++D ++ + S + S E+R Y DYD
Sbjct: 384 DSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQY----SDYD 427
>gi|42518070 tight junction protein 2 (zona occludens 2) isoform 1
[Homo sapiens]
Length = 1190
Score = 112 bits (279), Expect = 1e-24
Identities = 121/490 (24%), Positives = 196/490 (40%), Gaps = 99/490 (20%)
Query: 27 ASQRWAWPLRSLRPGGDARE----PRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGP 82
A Q A P LRP + K++ K +G + GG D GIFV+ I G
Sbjct: 485 APQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND-VGIFVAGIQEGTS 543
Query: 83 ADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRA--GQSVTIVAQYRPEEYSRFESKI 140
A+ G L+ GD+IL VN + R E A L G+ VTI+AQ R + Y
Sbjct: 544 AEQEG-LQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVY------- 595
Query: 141 HDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVIN 200
++ G G S ++R+ F+ ++ Q L+F+ G++ V++
Sbjct: 596 --------RDILACGRGD-------SFFIRSHFECEKETP-----QSLAFTRGEVFRVVD 635
Query: 201 ASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKR 260
D L G + G+IP+K R E+ + R ++
Sbjct: 636 TLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGV 695
Query: 261 KKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIH 320
KK+ R KS+E++ S+ + +YE V +E
Sbjct: 696 KKNLR--------KSREDLTAVVSVSTK-------------------FPAYERVLLREAG 728
Query: 321 YARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKD 380
+ RPV++ GP+ D + L +E P F + T P KD
Sbjct: 729 FKRPVVLFGPIADIAMEKLANELPDWFQTA---KTEP---------------------KD 764
Query: 381 IQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKP 440
K + N +VR + E+ KH +LDV+ A+ L Q +PI IF P
Sbjct: 765 AGSEKSTGVVRLN---------TVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNP 815
Query: 441 KSIEALMEMNRR---QTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEI-YNKIKQII 496
S + + M +R + + + K++D+A KL++ FTA + +S + + +K I
Sbjct: 816 DSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTATINLNSANDSWFGSLKDTI 875
Query: 497 EDQSGHYIWV 506
+ Q G +WV
Sbjct: 876 QHQQGEAVWV 885
Score = 47.4 bits (111), Expect = 3e-05
Identities = 34/95 (35%), Positives = 49/95 (51%), Gaps = 11/95 (11%)
Query: 46 EPRKIILHKGST-GLGFNIVGGED------GE-GIFVSFILAGGPADLSGELRRGDRILS 97
E + L K S G G + GG D GE I +S +L GGPAD G L+ DR++
Sbjct: 30 EQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPAD--GLLQENDRVVM 87
Query: 98 VNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEE 132
VNG + + H A L+++G+ IV + RP +
Sbjct: 88 VNGTPMEDVLHSFAVQQLRKSGKVAAIVVK-RPRK 121
Score = 32.3 bits (72), Expect = 1.1
Identities = 26/108 (24%), Positives = 44/108 (40%), Gaps = 4/108 (3%)
Query: 69 GEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQY 128
G IFV + G A G L GD IL +NG N + A ++++ + +V
Sbjct: 324 GSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLR 383
Query: 129 RPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYD 176
++ ++D ++ + S + S E+R Y DYD
Sbjct: 384 DSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQY----SDYD 427
>gi|226874833 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 102 bits (255), Expect = 6e-22
Identities = 62/186 (33%), Positives = 102/186 (54%), Gaps = 11/186 (5%)
Query: 323 RPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEK 379
RPV++ GP K + L+ E FG V HTTR R E +G+DY+FV +RE M++
Sbjct: 5 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFV-TREVMQR 63
Query: 380 DIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIK 439
DI FIE +F+ NLYGTS +V+AV + C+LDV ++ ++ L PI I ++
Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 123
Query: 440 PKSIEALMEMNRRQTYEQANKIYDKA------MKLEQEFGEYFTAIVQGDSLEEIYNKIK 493
P S+ L + R++ E + + M+ +E G F ++ DSL++ Y ++K
Sbjct: 124 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPG-LFDVVIINDSLDQAYAELK 182
Query: 494 QIIEDQ 499
+ + ++
Sbjct: 183 EALSEE 188
>gi|226874831 guanylate kinase 1 isoform a [Homo sapiens]
Length = 218
Score = 102 bits (255), Expect = 6e-22
Identities = 62/186 (33%), Positives = 102/186 (54%), Gaps = 11/186 (5%)
Query: 323 RPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEK 379
RPV++ GP K + L+ E FG V HTTR R E +G+DY+FV +RE M++
Sbjct: 26 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFV-TREVMQR 84
Query: 380 DIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIK 439
DI FIE +F+ NLYGTS +V+AV + C+LDV ++ ++ L PI I ++
Sbjct: 85 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 144
Query: 440 PKSIEALMEMNRRQTYEQANKIYDKA------MKLEQEFGEYFTAIVQGDSLEEIYNKIK 493
P S+ L + R++ E + + M+ +E G F ++ DSL++ Y ++K
Sbjct: 145 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPG-LFDVVIINDSLDQAYAELK 203
Query: 494 QIIEDQ 499
+ + ++
Sbjct: 204 EALSEE 209
>gi|4504221 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 102 bits (255), Expect = 6e-22
Identities = 62/186 (33%), Positives = 102/186 (54%), Gaps = 11/186 (5%)
Query: 323 RPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEK 379
RPV++ GP K + L+ E FG V HTTR R E +G+DY+FV +RE M++
Sbjct: 5 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFV-TREVMQR 63
Query: 380 DIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIK 439
DI FIE +F+ NLYGTS +V+AV + C+LDV ++ ++ L PI I ++
Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 123
Query: 440 PKSIEALMEMNRRQTYEQANKIYDKA------MKLEQEFGEYFTAIVQGDSLEEIYNKIK 493
P S+ L + R++ E + + M+ +E G F ++ DSL++ Y ++K
Sbjct: 124 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPG-LFDVVIINDSLDQAYAELK 182
Query: 494 QIIEDQ 499
+ + ++
Sbjct: 183 EALSEE 188
>gi|11545920 lin-7 homolog B [Homo sapiens]
Length = 207
Score = 83.6 bits (205), Expect = 4e-16
Identities = 50/113 (44%), Positives = 68/113 (60%), Gaps = 6/113 (5%)
Query: 47 PRKIILHKGSTGLGFNIVGG-EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRN 105
PR + L K GLGFNI+GG E I++S ++ GG AD G L+RGD++LSVNGV++
Sbjct: 91 PRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEG 150
Query: 106 ATHEQAAAALKRAGQSVTIVAQYRP----EEYSRFESKIHDLREQMMNSSMSS 154
HE+A LK A SV +V +Y P E +RFE K+ R + + S SS
Sbjct: 151 EQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFE-KMRSARRRQQHQSYSS 202
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,227,096
Number of Sequences: 37866
Number of extensions: 798162
Number of successful extensions: 3301
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 2704
Number of HSP's gapped (non-prelim): 560
length of query: 512
length of database: 18,247,518
effective HSP length: 107
effective length of query: 405
effective length of database: 14,195,856
effective search space: 5749321680
effective search space used: 5749321680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.