Guide to the Human Genome
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Search of human proteins with 239755390

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo
sapiens]
         (1662 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]    3549   0.0  
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...  3200   0.0  
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...  3200   0.0  
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...  3175   0.0  
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]    3172   0.0  
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...   747   0.0  
gi|44889963 CD163 antigen isoform b [Homo sapiens]                    721   0.0  
gi|44662834 CD163 antigen isoform a [Homo sapiens]                    721   0.0  
gi|18152779 scavenger receptor cysteine rich domain containing, ...   511   e-144
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]            485   e-136
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]           481   e-135
gi|4506143 neurotrypsin precursor [Homo sapiens]                      356   1e-97
gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]      296   9e-80
gi|5174411 CD5 molecule-like [Homo sapiens]                           269   1e-71
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]             268   3e-71
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]             264   5e-70
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]              257   8e-68
gi|194018748 CD6 molecule [Homo sapiens]                              241   4e-63
gi|22547221 tolloid-like 1 [Homo sapiens]                             151   6e-36
gi|6912724 tolloid-like 2 [Homo sapiens]                              144   5e-34
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom...   138   4e-32
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom...   138   4e-32
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...   138   4e-32
gi|72384339 CUB domain containing protein 2 [Homo sapiens]            136   2e-31
gi|5031863 galectin 3 binding protein [Homo sapiens]                  134   1e-30
gi|126091152 cubilin [Homo sapiens]                                   125   3e-28
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]             122   4e-27
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]       114   8e-25
gi|5803080 macrophage receptor with collagenous structure [Homo ...   110   9e-24
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo...   105   4e-22

>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score = 3549 bits (9204), Expect = 0.0
 Identities = 1662/1662 (100%), Positives = 1662/1662 (100%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480

Query: 481  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540
            TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 481  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540

Query: 541  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
            LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS
Sbjct: 541  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600

Query: 601  AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 660
            AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT
Sbjct: 601  AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 660

Query: 661  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 720
            NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH
Sbjct: 661  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 720

Query: 721  SEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWG 780
            SEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWG
Sbjct: 721  SEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWG 780

Query: 781  TVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHN 840
            TVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHN
Sbjct: 781  TVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHN 840

Query: 841  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 900
            GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG
Sbjct: 841  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 900

Query: 901  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960
            RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG
Sbjct: 901  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960

Query: 961  NESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLF 1020
            NESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLF
Sbjct: 961  NESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLF 1020

Query: 1021 YASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSL 1080
            YASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSL
Sbjct: 1021 YASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSL 1080

Query: 1081 NSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSS 1140
            NSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSS
Sbjct: 1081 NSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSS 1140

Query: 1141 YGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLD 1200
            YGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLD
Sbjct: 1141 YGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLD 1200

Query: 1201 DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGF 1260
            DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGF
Sbjct: 1201 DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGF 1260

Query: 1261 LSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPY 1320
            LSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPY
Sbjct: 1261 LSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPY 1320

Query: 1321 RSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNH 1380
            RSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNH
Sbjct: 1321 RSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNH 1380

Query: 1381 MQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTI 1440
            MQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTI
Sbjct: 1381 MQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTI 1440

Query: 1441 DYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYG 1500
            DYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYG
Sbjct: 1441 DYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYG 1500

Query: 1501 NFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDF 1560
            NFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDF
Sbjct: 1501 NFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDF 1560

Query: 1561 TSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPS 1620
            TSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPS
Sbjct: 1561 TSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPS 1620

Query: 1621 SRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1662
            SRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR
Sbjct: 1621 SRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1662


>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
            [Homo sapiens]
          Length = 2403

 Score = 3200 bits (8297), Expect = 0.0
 Identities = 1503/1590 (94%), Positives = 1527/1590 (96%), Gaps = 11/1590 (0%)

Query: 75   TVAEGSLIPSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWD 132
            +V++    PS  T  ++ A   G +S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWD
Sbjct: 823  SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD 882

Query: 133  TNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCG 192
            T+DANVVCRQLGCGWA SAPGNA FGQGSGPI LDDVRCSG+ESYLWSCPHNGWLSHNC 
Sbjct: 883  TSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQ 942

Query: 193  HGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYR 252
            H EDAGVICSAA   ST  P++ P  I+ P  T GSESSLALRLVNGGDRC+GRVEVLY+
Sbjct: 943  HSEDAGVICSAAHSWSTPSPDTLPT-ITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQ 1001

Query: 253  GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 312
            GSWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSGHESYLWS
Sbjct: 1002 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1061

Query: 313  CPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 372
            CPHNGWL+HNCGHSEDAGVICSA QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
Sbjct: 1062 CPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1121

Query: 373  QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432
            QGRVEVLYRGSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRC
Sbjct: 1122 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 1181

Query: 433  SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTV 492
            SG+ESYLWSCPHNGWLSHNC H EDAGVICSA+ S  TPSP      DT PT    AST 
Sbjct: 1182 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSP------DTWPTSH--ASTA 1233

Query: 493  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 552
            GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWA  APGN
Sbjct: 1234 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 1293

Query: 553  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDT 612
            ARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICSA+QS+ TP PDT
Sbjct: 1294 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1353

Query: 613  WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 672
            WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGC
Sbjct: 1354 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1413

Query: 673  GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQ 732
            GWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICSASQ
Sbjct: 1414 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1473

Query: 733  SRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA 792
            S+PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA
Sbjct: 1474 SQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA 1533

Query: 793  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 852
            NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED
Sbjct: 1534 NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1593

Query: 853  AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 912
            AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT
Sbjct: 1594 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 1653

Query: 913  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG 972
            VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG
Sbjct: 1654 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG 1713

Query: 973  WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1032
            WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP
Sbjct: 1714 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1773

Query: 1033 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND 1092
            AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND
Sbjct: 1774 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND 1833

Query: 1093 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH 1152
            TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH
Sbjct: 1834 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH 1893

Query: 1153 GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW 1212
            GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW
Sbjct: 1894 GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW 1953

Query: 1213 QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF 1272
            QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF
Sbjct: 1954 QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF 2013

Query: 1273 YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG 1332
            YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG
Sbjct: 2014 YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG 2073

Query: 1333 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS 1392
            ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS
Sbjct: 2074 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS 2133

Query: 1393 LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG 1452
            LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG
Sbjct: 2134 LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG 2193

Query: 1453 GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS 1512
            GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS
Sbjct: 2194 GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS 2253

Query: 1513 SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC 1572
            SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC
Sbjct: 2254 SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC 2313

Query: 1573 VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK 1632
            VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK
Sbjct: 2314 VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK 2373

Query: 1633 RDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1662
            RDVGSYQEKVDVVLGPIQLQTPPRREEEPR
Sbjct: 2374 RDVGSYQEKVDVVLGPIQLQTPPRREEEPR 2403



 Score = 2065 bits (5351), Expect = 0.0
 Identities = 1009/1277 (79%), Positives = 1044/1277 (81%), Gaps = 88/1277 (6%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS                D
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS----------------D 464

Query: 481  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540
            TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 465  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 524

Query: 541  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
            LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS
Sbjct: 525  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 584

Query: 601  AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 660
                                 G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDT
Sbjct: 585  ---------------------GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 623

Query: 661  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 720
            NDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGH
Sbjct: 624  NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGH 683

Query: 721  SEDAGVICSASQSRPTPSPDTWPTSR--ASTAGSESTLALRLVNGGDRCRGRVEVLYQGS 778
             EDAGVICSA+QSR TP PDT  T     ST GSES+L LRLVNG DRC+GRVEVLY+GS
Sbjct: 684  HEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGS 743

Query: 779  WGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCP 838
            WGTVCDD WDTNDANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP
Sbjct: 744  WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP 803

Query: 839  HNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRC 898
            HNGWLSHNCGHHEDAGVICS +QS+ TP PDTW T++  A T G ESSLALRLVNGGDRC
Sbjct: 804  HNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSH--ASTAGPESSLALRLVNGGDRC 861

Query: 899  RGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 958
            +GRVEVLYRGSWGTVCDDSWDT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRC
Sbjct: 862  QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 921

Query: 959  SGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTA--------- 1009
            SG ESYLWSCPH GWL+HNC H EDAGVICSA    ST +    PT T  A         
Sbjct: 922  SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 981

Query: 1010 -----RPSSNCGG---FLFYAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLG 1056
                      C G    L+  S GT    S+     N       C W +      R   G
Sbjct: 982  ALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1041

Query: 1057 FSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRMTIHF 1108
               + L+    CS     ++    N  L          G IC+ ++   T S +      
Sbjct: 1042 SGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSH 1100

Query: 1109 RSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQE 1168
             S    +            S   LRLVN       C GRVE+ + G+WGTVCDD W   +
Sbjct: 1101 ASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYWDTND 1145

Query: 1169 AEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRE 1228
            A VVCRQLGCG A+SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H E
Sbjct: 1146 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1205

Query: 1229 DAGVICSGNHLS-TPAP 1244
            DAGVICS +    TP+P
Sbjct: 1206 DAGVICSASQSQPTPSP 1222



 Score =  604 bits (1558), Expect = e-172
 Identities = 320/540 (59%), Positives = 352/540 (65%), Gaps = 55/540 (10%)

Query: 737  PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 796
            PS  T  ++ A   GS+S LALRLVNG  RC+GRVE+LY+GSWGTVCDD WDTNDANVVC
Sbjct: 83   PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140

Query: 797  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 856
            RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI
Sbjct: 141  RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200

Query: 857  CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 915
            CSAAQ QST RP++W +  + P  T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD
Sbjct: 201  CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260

Query: 916  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 975
            D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT
Sbjct: 261  DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320

Query: 976  HNCGHHEDAGVICSATQINSTTT-DWWHPTTTTTARPSSN-----------CGG---FLF 1020
            HNCGH EDAGVICSA Q   T + D W  +  +TA P S+           C G    L+
Sbjct: 321  HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380

Query: 1021 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1075
              S GT    S+     N       C W        R   G   + L+    CS     +
Sbjct: 381  RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD-DVRCSGYESYL 439

Query: 1076 FDGSLNSSLL--------LGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1127
            +    N  L          G IC+DT    T   + +                       
Sbjct: 440  WSCPHNGWLSHNCQHSEDAGVICSDTLPTITLPASTV--------------------GSE 479

Query: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
            S   LRLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A+ A GN
Sbjct: 480  SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 536

Query: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLN 1247
            A FG GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG   S     +N
Sbjct: 537  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVN 596


>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
            [Homo sapiens]
          Length = 2413

 Score = 3200 bits (8297), Expect = 0.0
 Identities = 1503/1590 (94%), Positives = 1527/1590 (96%), Gaps = 11/1590 (0%)

Query: 75   TVAEGSLIPSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWD 132
            +V++    PS  T  ++ A   G +S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWD
Sbjct: 833  SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD 892

Query: 133  TNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCG 192
            T+DANVVCRQLGCGWA SAPGNA FGQGSGPI LDDVRCSG+ESYLWSCPHNGWLSHNC 
Sbjct: 893  TSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQ 952

Query: 193  HGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYR 252
            H EDAGVICSAA   ST  P++ P  I+ P  T GSESSLALRLVNGGDRC+GRVEVLY+
Sbjct: 953  HSEDAGVICSAAHSWSTPSPDTLPT-ITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQ 1011

Query: 253  GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 312
            GSWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSGHESYLWS
Sbjct: 1012 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1071

Query: 313  CPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 372
            CPHNGWL+HNCGHSEDAGVICSA QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
Sbjct: 1072 CPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1131

Query: 373  QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432
            QGRVEVLYRGSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRC
Sbjct: 1132 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 1191

Query: 433  SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTV 492
            SG+ESYLWSCPHNGWLSHNC H EDAGVICSA+ S  TPSP      DT PT    AST 
Sbjct: 1192 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSP------DTWPTSH--ASTA 1243

Query: 493  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 552
            GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWA  APGN
Sbjct: 1244 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 1303

Query: 553  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDT 612
            ARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICSA+QS+ TP PDT
Sbjct: 1304 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1363

Query: 613  WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 672
            WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGC
Sbjct: 1364 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1423

Query: 673  GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQ 732
            GWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICSASQ
Sbjct: 1424 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1483

Query: 733  SRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA 792
            S+PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA
Sbjct: 1484 SQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA 1543

Query: 793  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 852
            NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED
Sbjct: 1544 NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1603

Query: 853  AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 912
            AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT
Sbjct: 1604 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 1663

Query: 913  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG 972
            VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG
Sbjct: 1664 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG 1723

Query: 973  WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1032
            WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP
Sbjct: 1724 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1783

Query: 1033 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND 1092
            AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND
Sbjct: 1784 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND 1843

Query: 1093 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH 1152
            TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH
Sbjct: 1844 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH 1903

Query: 1153 GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW 1212
            GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW
Sbjct: 1904 GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW 1963

Query: 1213 QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF 1272
            QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF
Sbjct: 1964 QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF 2023

Query: 1273 YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG 1332
            YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG
Sbjct: 2024 YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG 2083

Query: 1333 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS 1392
            ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS
Sbjct: 2084 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS 2143

Query: 1393 LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG 1452
            LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG
Sbjct: 2144 LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG 2203

Query: 1453 GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS 1512
            GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS
Sbjct: 2204 GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS 2263

Query: 1513 SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC 1572
            SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC
Sbjct: 2264 SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC 2323

Query: 1573 VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK 1632
            VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK
Sbjct: 2324 VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK 2383

Query: 1633 RDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1662
            RDVGSYQEKVDVVLGPIQLQTPPRREEEPR
Sbjct: 2384 RDVGSYQEKVDVVLGPIQLQTPPRREEEPR 2413



 Score = 2092 bits (5419), Expect = 0.0
 Identities = 1019/1277 (79%), Positives = 1054/1277 (82%), Gaps = 78/1277 (6%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP      D
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP------D 474

Query: 481  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540
            TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 475  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 534

Query: 541  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
            LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS
Sbjct: 535  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594

Query: 601  AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 660
                                 G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDT
Sbjct: 595  ---------------------GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 633

Query: 661  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 720
            NDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGH
Sbjct: 634  NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGH 693

Query: 721  SEDAGVICSASQSRPTPSPDTWPTSR--ASTAGSESTLALRLVNGGDRCRGRVEVLYQGS 778
             EDAGVICSA+QSR TP PDT  T     ST GSES+L LRLVNG DRC+GRVEVLY+GS
Sbjct: 694  HEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGS 753

Query: 779  WGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCP 838
            WGTVCDD WDTNDANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP
Sbjct: 754  WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP 813

Query: 839  HNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRC 898
            HNGWLSHNCGHHEDAGVICS +QS+ TP PDTW T++  A T G ESSLALRLVNGGDRC
Sbjct: 814  HNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSH--ASTAGPESSLALRLVNGGDRC 871

Query: 899  RGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 958
            +GRVEVLYRGSWGTVCDDSWDT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRC
Sbjct: 872  QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 931

Query: 959  SGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTA--------- 1009
            SG ESYLWSCPH GWL+HNC H EDAGVICSA    ST +    PT T  A         
Sbjct: 932  SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 991

Query: 1010 -----RPSSNCGG---FLFYAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLG 1056
                      C G    L+  S GT    S+     N       C W +      R   G
Sbjct: 992  ALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1051

Query: 1057 FSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRMTIHF 1108
               + L+    CS     ++    N  L          G IC+ ++   T S +      
Sbjct: 1052 SGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSH 1110

Query: 1109 RSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQE 1168
             S    +            S   LRLVN       C GRVE+ + G+WGTVCDD W   +
Sbjct: 1111 ASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYWDTND 1155

Query: 1169 AEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRE 1228
            A VVCRQLGCG A+SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H E
Sbjct: 1156 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1215

Query: 1229 DAGVICSGNHLS-TPAP 1244
            DAGVICS +    TP+P
Sbjct: 1216 DAGVICSASQSQPTPSP 1232



 Score =  602 bits (1552), Expect = e-171
 Identities = 319/535 (59%), Positives = 355/535 (66%), Gaps = 35/535 (6%)

Query: 737  PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 796
            PS  T  ++ A   GS+S LALRLVNG  RC+GRVE+LY+GSWGTVCDD WDTNDANVVC
Sbjct: 83   PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140

Query: 797  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 856
            RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI
Sbjct: 141  RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200

Query: 857  CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 915
            CSAAQ QST RP++W +  + P  T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD
Sbjct: 201  CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260

Query: 916  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 975
            D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT
Sbjct: 261  DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320

Query: 976  HNCGHHEDAGVICSATQINSTTT-DWWHPTTTTTARPSSN-----------CGG---FLF 1020
            HNCGH EDAGVICSA Q   T + D W  +  +TA P S+           C G    L+
Sbjct: 321  HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380

Query: 1021 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1075
              S GT    S+     N       C W        R   G   + L+      +   E 
Sbjct: 381  RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGY---ES 437

Query: 1076 FDGSLNSSLLLGKICN---DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATL 1132
            +  S   +  L   C    D   I +++++  T    S  +       A      S   L
Sbjct: 438  YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST---PSPDTLPTITLPASTVGSESSLAL 494

Query: 1133 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1192
            RLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A+ A GNA FG 
Sbjct: 495  RLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ 551

Query: 1193 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLN 1247
            GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG   S     +N
Sbjct: 552  GSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVN 606


>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
            [Homo sapiens]
          Length = 1785

 Score = 3175 bits (8233), Expect = 0.0
 Identities = 1490/1571 (94%), Positives = 1512/1571 (96%), Gaps = 13/1571 (0%)

Query: 94   EGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPG 153
            EGS+S LALRLVNG  RC+GRVE+LYRGSWGTVCDD WDTNDANVVCRQLGCGWAMSAPG
Sbjct: 226  EGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 285

Query: 154  NAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPE 213
            NA FGQGSGPI LDDVRCSGHESYLWSCPHNGWL+HNCGH EDAGVICSA Q + T  P+
Sbjct: 286  NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPD 345

Query: 214  SWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCR 273
            +WP   +    T G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDT+DANVVCR
Sbjct: 346  TWP---TSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCR 402

Query: 274  QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVIC 333
            QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNC HSEDAGVIC
Sbjct: 403  QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 462

Query: 334  SAPQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 391
            SA  S  TPSPDT PT    AST GSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDS
Sbjct: 463  SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDS 522

Query: 392  WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 451
            WDT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHN
Sbjct: 523  WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 582

Query: 452  CQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQG 511
            C HSEDAGVICSA+ S  TPSP      DT PT    AST GSESSLALRLVNGGDRCQG
Sbjct: 583  CGHSEDAGVICSASQSRPTPSP------DTWPTSH--ASTAGSESSLALRLVNGGDRCQG 634

Query: 512  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSG 571
            RVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWAM APGNARFGQGSGPIVLDDVRCSG
Sbjct: 635  RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 694

Query: 572  NESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRL 631
            +ESYLWSCPHNGWLSHNCGH EDAGVICSA+QS+ TP PDTWPTSHASTAGSESSLALRL
Sbjct: 695  HESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRL 754

Query: 632  VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 691
            VNGGDRCQGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWA SAPGNARFGQGSGPI
Sbjct: 755  VNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPI 814

Query: 692  VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAG 751
            VLDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICSASQS+PTPSPDTWPTSRASTAG
Sbjct: 815  VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAG 874

Query: 752  SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 811
            SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA
Sbjct: 875  SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 934

Query: 812  QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 871
            QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW
Sbjct: 935  QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 994

Query: 872  LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 931
            LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG
Sbjct: 995  LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 1054

Query: 932  CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 991
            CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT
Sbjct: 1055 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 1114

Query: 992  QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY 1051
            QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY
Sbjct: 1115 QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY 1174

Query: 1052 RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1111
            RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD
Sbjct: 1175 RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1234

Query: 1112 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV 1171
            ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV
Sbjct: 1235 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV 1294

Query: 1172 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG 1231
            VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG
Sbjct: 1295 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG 1354

Query: 1232 VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN 1291
            VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN
Sbjct: 1355 VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN 1414

Query: 1292 NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD 1351
            NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD
Sbjct: 1415 NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD 1474

Query: 1352 HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC 1411
            HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC
Sbjct: 1475 HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC 1534

Query: 1412 RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ 1471
            RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ
Sbjct: 1535 RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ 1594

Query: 1472 NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL 1531
            NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL
Sbjct: 1595 NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL 1654

Query: 1532 YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF 1591
            YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF
Sbjct: 1655 YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF 1714

Query: 1592 RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL 1651
            RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL
Sbjct: 1715 RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL 1774

Query: 1652 QTPPRREEEPR 1662
            QTPPRREEEPR
Sbjct: 1775 QTPPRREEEPR 1785



 Score = 2058 bits (5332), Expect = 0.0
 Identities = 954/1005 (94%), Positives = 970/1005 (96%), Gaps = 9/1005 (0%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP      D
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP------D 474

Query: 481  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540
            TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCRQ
Sbjct: 475  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQ 534

Query: 541  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
            LGCGWAM APGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGHSEDAGVICS
Sbjct: 535  LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 594

Query: 601  AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 660
            A+QSR TP PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDD WDT
Sbjct: 595  ASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 654

Query: 661  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 720
            NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH
Sbjct: 655  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 714

Query: 721  SEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWG 780
             EDAGVICSASQS+PTPSPDTWPTS ASTAGSES+LALRLVNGGDRC+GRVEVLY+GSWG
Sbjct: 715  HEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWG 774

Query: 781  TVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHN 840
            TVCDDYWDTNDANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCPHN
Sbjct: 775  TVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHN 834

Query: 841  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 900
            GWLSHNCGHHEDAGVICSA+QSQ TP PDTW T+   A T GSES+LALRLVNGGDRCRG
Sbjct: 835  GWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSR--ASTAGSESTLALRLVNGGDRCRG 892

Query: 901  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960
            RVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG
Sbjct: 893  RVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSG 952

Query: 961  NESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPT 1004
            +ESYLWSCPH GWL+HNCGHHEDAGVICSA Q  ST   D W  T
Sbjct: 953  HESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTT 997



 Score = 1109 bits (2869), Expect = 0.0
 Identities = 549/797 (68%), Positives = 601/797 (75%), Gaps = 50/797 (6%)

Query: 482  LPTITLPASTV--GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 539
            +P+ +   STV  GS+S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCR
Sbjct: 82   IPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCR 141

Query: 540  QLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVIC 599
            QLGCGWAM APGNA FGQGSGPI LDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVIC
Sbjct: 142  QLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201

Query: 600  SAAQSRSTPRPDTWP---TSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 656
            SAAQ +ST RP++WP   +    T GSESSLALRLVNGGDRC+GRVEVLY+GSWGTVCDD
Sbjct: 202  SAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDD 261

Query: 657  SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 716
             WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCPHNGWL+H
Sbjct: 262  YWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTH 321

Query: 717  NCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQ 776
            NCGHSEDAGVICSA QSRPTPSPDTWPTS ASTAG ES+LALRLVNGGDRC+GRVEVLY+
Sbjct: 322  NCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYR 381

Query: 777  GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 836
            GSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWS
Sbjct: 382  GSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWS 441

Query: 837  CPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGD 896
            CPHNGWLSHNC H EDAGVICSAA S STP PDT  T  LPA TVGSESSLALRLVNGGD
Sbjct: 442  CPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGD 501

Query: 897  RCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 956
            RC+GRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV
Sbjct: 502  RCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 561

Query: 957  RCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPTTTTTARPSSN- 1014
            RCSG+ESYLWSCPH GWL+HNCGH EDAGVICSA+Q   T + D W  +  +TA   S+ 
Sbjct: 562  RCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSL 621

Query: 1015 ----------CGGFL-FYASGTFSSPSYPAYYPNNAK-------CVWEIEVNSGYRINLG 1056
                      C G +     G++ +     +  N+A        C W +      R   G
Sbjct: 622  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 681

Query: 1057 FSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRMTIHF 1108
               + L+    CS     ++    N  L          G IC+ ++   T S +      
Sbjct: 682  SGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSH 740

Query: 1109 RSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQE 1168
             S    +            S   LRLVN       C GRVE+ + G+WGTVCDD W   +
Sbjct: 741  ASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYWDTND 785

Query: 1169 AEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRE 1228
            A VVCRQLGCG A SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H E
Sbjct: 786  ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 845

Query: 1229 DAGVICSGNHLS-TPAP 1244
            DAGVICS +    TP+P
Sbjct: 846  DAGVICSASQSQPTPSP 862


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score = 3172 bits (8224), Expect = 0.0
 Identities = 1490/1571 (94%), Positives = 1509/1571 (96%), Gaps = 10/1571 (0%)

Query: 94   EGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPG 153
            EGS+S LALRLVNG  RC+GRVE+LYRGSWGTVCDD WDTNDANVVCRQLGCGWAMSAPG
Sbjct: 226  EGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 285

Query: 154  NAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPE 213
            NA FGQGSGPI LDDVRCSGHESYLWSCPHNGWL+HNCGH EDAGVICSA Q + T  P+
Sbjct: 286  NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPD 345

Query: 214  SWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCR 273
            +WP   +    T GSESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDT+DANVVCR
Sbjct: 346  TWP---TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCR 402

Query: 274  QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVIC 333
            QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNC HSEDAGVIC
Sbjct: 403  QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 462

Query: 334  SAPQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 391
            SA  S  TPSPDT PT    AST GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS
Sbjct: 463  SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 522

Query: 392  WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 451
            WDT+DANVVCRQLGCGWA  APGNARFGQGSGPIVLDDVRCSG ESYLWSCPHNGWLSHN
Sbjct: 523  WDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN 582

Query: 452  CQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQG 511
            C HSEDAGVICSA     TP      R  + P+     +  G ESSLALRLVNGGDRCQG
Sbjct: 583  CGHSEDAGVICSALQWLPTPI-----RPRSWPSSHALQTCKGPESSLALRLVNGGDRCQG 637

Query: 512  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSG 571
            RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA  APGNARFGQGSGPIVLDDVRCSG
Sbjct: 638  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 697

Query: 572  NESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRL 631
            +ESYLWSCP+NGWLSHNCGH EDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRL
Sbjct: 698  HESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRL 757

Query: 632  VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 691
            VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI
Sbjct: 758  VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 817

Query: 692  VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAG 751
            VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAG
Sbjct: 818  VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAG 877

Query: 752  SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 811
            SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA
Sbjct: 878  SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 937

Query: 812  QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 871
            QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW
Sbjct: 938  QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 997

Query: 872  LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 931
            LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG
Sbjct: 998  LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 1057

Query: 932  CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 991
            CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT
Sbjct: 1058 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 1117

Query: 992  QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY 1051
            QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY
Sbjct: 1118 QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY 1177

Query: 1052 RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1111
            RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD
Sbjct: 1178 RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1237

Query: 1112 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV 1171
            ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV
Sbjct: 1238 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV 1297

Query: 1172 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG 1231
            VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG
Sbjct: 1298 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG 1357

Query: 1232 VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN 1291
            VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN
Sbjct: 1358 VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN 1417

Query: 1292 NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD 1351
            NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD
Sbjct: 1418 NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD 1477

Query: 1352 HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC 1411
            HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC
Sbjct: 1478 HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC 1537

Query: 1412 RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ 1471
            RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ
Sbjct: 1538 RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ 1597

Query: 1472 NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL 1531
            NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL
Sbjct: 1598 NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL 1657

Query: 1532 YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF 1591
            YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF
Sbjct: 1658 YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF 1717

Query: 1592 RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL 1651
            RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL
Sbjct: 1718 RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL 1777

Query: 1652 QTPPRREEEPR 1662
            QTPPRREEEPR
Sbjct: 1778 QTPPRREEEPR 1788



 Score = 2031 bits (5263), Expect = 0.0
 Identities = 948/1008 (94%), Positives = 965/1008 (95%), Gaps = 12/1008 (1%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP      D
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP------D 474

Query: 481  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540
            TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 475  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 534

Query: 541  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
            LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS
Sbjct: 535  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594

Query: 601  AAQSRSTP-RPDTWPTSHA--STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDS 657
            A Q   TP RP +WP+SHA  +  G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDS
Sbjct: 595  ALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 654

Query: 658  WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 717
            WDTNDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHN
Sbjct: 655  WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHN 714

Query: 718  CGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG 777
            CGH EDAGVICSA+QSR TP PDTWPTS ASTAGSES+LALRLVNGGDRC+GRVEVLYQG
Sbjct: 715  CGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQG 774

Query: 778  SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837
            SWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSGHESYLWSC
Sbjct: 775  SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 834

Query: 838  PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897
            PHNGWLSHNCGH EDAGVICSA+QS+ TP PDTW T+   A T GSES+LALRLVNGGDR
Sbjct: 835  PHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSR--ASTAGSESTLALRLVNGGDR 892

Query: 898  CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957
            CRGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVR
Sbjct: 893  CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVR 952

Query: 958  CSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPT 1004
            CSG+ESYLWSCPH GWL+HNCGHHEDAGVICSA Q  ST   D W  T
Sbjct: 953  CSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTT 1000



 Score =  596 bits (1537), Expect = e-170
 Identities = 320/531 (60%), Positives = 354/531 (66%), Gaps = 36/531 (6%)

Query: 737  PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 796
            PS  T  ++ A   GS+S LALRLVNG  RC+GRVE+LY+GSWGTVCDD WDTNDANVVC
Sbjct: 83   PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140

Query: 797  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 856
            RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI
Sbjct: 141  RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200

Query: 857  CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 915
            CSAAQ QST RP++W +  + P  T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD
Sbjct: 201  CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260

Query: 916  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 975
            D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT
Sbjct: 261  DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320

Query: 976  HNCGHHEDAGVICSATQINST-TTDWWHPTTTTTARPSSN-----------CGG---FLF 1020
            HNCGH EDAGVICSA Q   T + D W  +  +TA   S+           C G    L+
Sbjct: 321  HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY 380

Query: 1021 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1075
              S GT    S+     N       C W        R   G   + L+    CS    E 
Sbjct: 381  RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD-DVRCS--GYES 437

Query: 1076 FDGSLNSSLLLGKIC---NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATL 1132
            +  S   +  L   C    D   I +++++  T    S  +       A      S   L
Sbjct: 438  YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST---PSPDTLPTITLPASTVGSESSLAL 494

Query: 1133 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1192
            RLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A+ A GNA FG 
Sbjct: 495  RLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ 551

Query: 1193 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG-NHLSTP 1242
            GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICS    L TP
Sbjct: 552  GSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTP 602


>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
            sapiens]
          Length = 1453

 Score =  747 bits (1929), Expect = 0.0
 Identities = 430/1151 (37%), Positives = 573/1151 (49%), Gaps = 176/1151 (15%)

Query: 97   DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAW 156
            ++ L LRLV+G+  C GRVE+ ++  WGT+CDD W+ N A VVCRQLGC  +  + G   
Sbjct: 150  EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVN 209

Query: 157  FGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWP 216
                  PI LDD+ C G+E  LW+C H GW +H+C H ED  + C               
Sbjct: 210  SPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY-------------- 255

Query: 217  VRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276
                         S L LRLV G +RC GRVE+  +G WGTVC   W+   A+VVC+QLG
Sbjct: 256  -----------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLG 304

Query: 277  CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336
            CG A+   G      GS  + LD V CSG+ES+LW C H+G +  +C H  D  VICS  
Sbjct: 305  CGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS-- 362

Query: 337  QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD 396
                                  + L LRL +G + C GRVEV     W T+CD +W    
Sbjct: 363  --------------------DGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQ 402

Query: 397  ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSE 456
            A VVC+QLGC ++      A+    +  I ++ + C+G ES LW C ++G     C    
Sbjct: 403  ALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRS 462

Query: 457  DAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVL 516
            DAGVICS             D+ D                 L LRLV     C GR+EV 
Sbjct: 463  DAGVICS-------------DKAD-----------------LDLRLVGAHSPCYGRLEVK 492

Query: 517  YRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYL 576
            Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDDV C GNES +
Sbjct: 493  YQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNI 552

Query: 577  WSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGD 636
            W C H+GW  HNC H ED  V CS           TW               LRLV G +
Sbjct: 553  WDCEHSGWGKHNCVHREDVIVTCSGDA--------TW--------------GLRLVGGSN 590

Query: 637  RCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 696
            RC GR+EV +QG WGTVCDD W++  A VVC QL C  ++   G      G G I LDDV
Sbjct: 591  RCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDV 650

Query: 697  RCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTL 756
             C G ES LWSC ++GW +++C HSED GVICS +                      S +
Sbjct: 651  SCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA----------------------SDM 688

Query: 757  ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 816
             LRLV G  RC G+VEV  QG+ G +C + W  N A VVCRQL CG A+       F + 
Sbjct: 689  ELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTER 748

Query: 817  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 876
            +  I++ +  C+G E+ LW C    W    C  + +A +ICSA +               
Sbjct: 749  TLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP------------- 795

Query: 877  PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 936
                         RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+
Sbjct: 796  -------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAI 842

Query: 937  SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 996
            S      FG+G+G    +  +C G+E++L  CP        C H  + GV+CS       
Sbjct: 843  SLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY----- 897

Query: 997  TTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRIN- 1054
                   T        S C G +     G + S     + P +A+ +   +++ G  ++ 
Sbjct: 898  -------TDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCR-QLSCGTALST 949

Query: 1055 -----LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---NDTRQIFTSSYNRMTI 1106
                 +G  ++++  H         + D +   ++L    C   N    I T S  +   
Sbjct: 950  TGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNTVSVICTGSLTQPLF 1008

Query: 1107 HFRSDISFQNTGFLAWYNSFP--SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW 1164
               +++S      +   ++     D  LRLV+ +S    CAGRVEIYH G WGT+CDD W
Sbjct: 1009 PCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEIYHDGFWGTICDDGW 1065

Query: 1165 TIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNC 1224
             + +A VVC++LGCG A +A  +A+FG GSGPI LDD+ C+G ES LWQC +RGW  H+C
Sbjct: 1066 DLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDC 1125

Query: 1225 NHREDAGVICS 1235
             H+EDAGVICS
Sbjct: 1126 RHKEDAGVICS 1136



 Score =  680 bits (1755), Expect = 0.0
 Identities = 364/902 (40%), Positives = 464/902 (51%), Gaps = 151/902 (16%)

Query: 92  VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151
           ++  + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T  + VVC+QLGC ++ + 
Sbjct: 38  ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97

Query: 152 PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208
                FGQ     G I LDDV C G+ES LW C H  W SHNC HGED GV C       
Sbjct: 98  ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----- 149

Query: 209 TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268
                               E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A
Sbjct: 150 --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189

Query: 269 NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328
            VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW  H+C H+ED
Sbjct: 190 AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249

Query: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
             + C                         S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 250 VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287

Query: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
              W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 288 HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347

Query: 449 SHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR 508
           + +C H  D  VICS                                + L LRL +G + 
Sbjct: 348 NFDCLHQNDVSVICSDG------------------------------ADLELRLADGSNN 377

Query: 509 CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVR 568
           C GRVEV     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + 
Sbjct: 378 CSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSIS 437

Query: 569 CSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLA 628
           C+GNES LW C ++G     C    DAGVICS                       ++ L 
Sbjct: 438 CTGNESALWDCTYDGKAKRTCFRRSDAGVICS----------------------DKADLD 475

Query: 629 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 688
           LRLV     C GR+EV YQG WGTVC D W T +A VVC+QLGCG  M   G   F + S
Sbjct: 476 LRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEAS 535

Query: 689 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRAS 748
           GPI LDDV C G+ES +W C H+GW  HNC H ED  V CS                   
Sbjct: 536 GPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS------------------- 576

Query: 749 TAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP 808
               ++T  LRLV G +RC GR+EV +QG WGTVCDD W++  A VVC QL C  ++   
Sbjct: 577 ---GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGM 633

Query: 809 GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRP 868
           G      G G I LDDV C G ES LWSC ++GW +++C H ED GVICS A        
Sbjct: 634 GLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA-------- 685

Query: 869 DTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCR 928
                           S + LRLV G  RC G+VEV  +G+ G +C + W  N A VVCR
Sbjct: 686 ----------------SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCR 729

Query: 929 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 988
           QL CG A+       F + +  I++ +  C+G E+ LW C    W    C  + +A +IC
Sbjct: 730 QLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLIC 789

Query: 989 SA 990
           SA
Sbjct: 790 SA 791



 Score =  606 bits (1563), Expect = e-173
 Identities = 349/916 (38%), Positives = 456/916 (49%), Gaps = 144/916 (15%)

Query: 97   DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAW 156
            D+   LRLV G  RC GR+E+ ++G WGTVCDD W++  A VVC QL C  ++   G   
Sbjct: 578  DATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGN 637

Query: 157  FGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWP 216
               G G I LDDV C G ES LWSC ++GW +++C H ED GVICS A            
Sbjct: 638  ASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA------------ 685

Query: 217  VRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276
                         S + LRLV G  RC G+VEV  +G+ G +C + W  N A VVCRQL 
Sbjct: 686  -------------SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLE 732

Query: 277  CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336
            CG A+       F + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA 
Sbjct: 733  CGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792

Query: 337  QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD 396
            +                          RLV     C GRVEV +  +W +VCD  +    
Sbjct: 793  RQP------------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHA 828

Query: 397  ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSE 456
            ANV+CR+L CG A S      FG+G+G    +  +C G E++L  CP        C HS 
Sbjct: 829  ANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSR 888

Query: 457  DAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVL 516
            + GV+CS               TD                   +RLVNG  +C G+VE+ 
Sbjct: 889  EVGVVCSRY-------------TD-------------------VRLVNGKSQCDGQVEIN 916

Query: 517  YRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYL 576
              G WG++CD  WD  DA V+CRQL CG A+   G    G+ S  +      C GNES L
Sbjct: 917  VLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLL 976

Query: 577  WSCPHNGWLSHNCGHSEDAGVICSAAQSR---------STPRPDTWPTSHASTAGSESSL 627
             +C      +  C H     VIC+ + ++         S P     P   A     +  L
Sbjct: 977  DNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRL 1036

Query: 628  ALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 687
              RLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+G
Sbjct: 1037 --RLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEG 1094

Query: 688  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRA 747
            SGPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS                  
Sbjct: 1095 SGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS------------------ 1136

Query: 748  STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 807
                  + L L      + C GR+EV Y G+WG+V      T  A +VCRQLGCG     
Sbjct: 1137 ----EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVV 1192

Query: 808  PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 867
                    GSG + +DD++C      +W C    W                  +  S+P 
Sbjct: 1193 SLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW-----------------ERRISSPA 1235

Query: 868  PDTWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSWGTVCDDSWDTNDANVV 926
             +TW+T          E  + +R   GGD  C GRVE+ + GSWGTVCDDSWD  +A VV
Sbjct: 1236 EETWIT---------CEDRIRVR---GGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVV 1283

Query: 927  CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 986
            C+QLGCG A++A  +A FGQG+G I LDD+RC GNES+LW C  K W   +CGH EDAGV
Sbjct: 1284 CQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGV 1343

Query: 987  ICSATQINSTTTDWWH 1002
             CS   + S      H
Sbjct: 1344 RCSGQSLKSLNASSGH 1359



 Score =  551 bits (1419), Expect = e-156
 Identities = 325/883 (36%), Positives = 422/883 (47%), Gaps = 138/883 (15%)

Query: 359  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF 418
            + L LRLVNG   C G VEV ++G WGTVCDD W+T+ + VVC+QLGC ++ +     RF
Sbjct: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100

Query: 419  GQG---SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGE 475
            GQ     G I LDDV C G ES LW C H  W SHNC H ED GV C             
Sbjct: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149

Query: 476  RDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 535
                               E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A 
Sbjct: 150  -------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAA 190

Query: 536  VVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDA 595
            VVCRQLGC  + ++ G         PI LDD+ C GNE  LW+C H GW +H+C H+ED 
Sbjct: 191  VVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDV 250

Query: 596  GVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 655
             + C                         S L LRLV G +RC GRVE+  QG WGTVC 
Sbjct: 251  TLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCH 288

Query: 656  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 715
              W+   A+VVC+QLGCG A+   G      GS  + LD V CSG+ES+LW C H+G ++
Sbjct: 289  HKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVN 348

Query: 716  HNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLY 775
             +C H  D  VICS                        + L LRL +G + C GRVEV  
Sbjct: 349  FDCLHQNDVSVICSDG----------------------ADLELRLADGSNNCSGRVEVRI 386

Query: 776  QGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLW 835
               W T+CD  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW
Sbjct: 387  HEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALW 446

Query: 836  SCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGG 895
             C ++G     C    DAGVICS                         ++ L LRLV   
Sbjct: 447  DCTYDGKAKRTCFRRSDAGVICS------------------------DKADLDLRLVGAH 482

Query: 896  DRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD 955
              C GR+EV Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDD
Sbjct: 483  SPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDD 542

Query: 956  VRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNC 1015
            V C GNES +W C H GW  HNC H ED  V C      S    W           S+ C
Sbjct: 543  VSCIGNESNIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRC 592

Query: 1016 GGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
             G L  Y  G + +     +    A  V          I +G  N       +  +  + 
Sbjct: 593  SGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIW 646

Query: 1075 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL 1134
            + D S +         +D      S +         D+     G +    S  SD  LRL
Sbjct: 647  LDDVSCDGDE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRL 692

Query: 1135 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1194
            V  +S    CAG+VE+   G  G +C + W +  AEVVCRQL CG A+      +F   +
Sbjct: 693  VGGSSR---CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERT 749

Query: 1195 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1237
              I + +  C+G E++LW C    W    C+   +A +ICS +
Sbjct: 750  LHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792



 Score =  307 bits (787), Expect = 5e-83
 Identities = 175/415 (42%), Positives = 221/415 (53%), Gaps = 67/415 (16%)

Query: 63   GSPISLESTLESTVAEGSL----IPSESTLE----STVAEGSD----SGLALRLVNGDGR 110
            G+P  +     S +  GSL     P  + +     S V EGS         LRLV+GD R
Sbjct: 985  GAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR 1044

Query: 111  CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVR 170
            C GRVEI + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+GSGPI LDD+ 
Sbjct: 1045 CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLN 1104

Query: 171  CSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSES 230
            C+G ES+LW CP  GW  H+C H EDAGVICS          E   +R+     TE    
Sbjct: 1105 CTGMESHLWQCPSRGWGQHDCRHKEDAGVICS----------EFTALRLYSETETES--- 1151

Query: 231  SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 290
                        C GR+EV Y G+WG+V      T  A +VCRQLGCG            
Sbjct: 1152 ------------CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSK 1199

Query: 291  QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR--PTPSPDTWP 348
             GSG + +DD++C      +W C                    SAP  R   +P+ +TW 
Sbjct: 1200 TGSGFMWVDDIQCPKTHISIWQC-------------------LSAPWERRISSPAEETWI 1240

Query: 349  TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGW 408
            T             +R+  G   C GRVE+ + GSWGTVCDDSWD ++A VVC+QLGCG 
Sbjct: 1241 TCED---------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291

Query: 409  ATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
            A +A  +A FGQG+G I LDD+RC G ES+LW C    W   +C H EDAGV CS
Sbjct: 1292 ALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346



 Score =  138 bits (348), Expect = 4e-32
 Identities = 59/98 (60%), Positives = 73/98 (74%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
            C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ 
Sbjct: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1241
            C G ES LW C  + W   +C H+EDAGV CSG  L +
Sbjct: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%)

Query: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1191
            +RLVN  S    C G+VEI   G WG++CD  W  ++A V+CRQL CG A+S  G  Y G
Sbjct: 900  VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956

Query: 1192 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 1250
              S  +      C G ES L  C+     +  C H     VIC+G+      P L N++ 
Sbjct: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016

Query: 1251 P 1251
            P
Sbjct: 1017 P 1017



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 33/91 (36%), Positives = 51/91 (56%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
            CAGR+E+++ GTWG+V   + T   A +VCRQLGCG            +GSG + +DD++
Sbjct: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
            C  T  ++WQC +  W     +  E+  + C
Sbjct: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242


>gi|44889963 CD163 antigen isoform b [Homo sapiens]
          Length = 1121

 Score =  721 bits (1862), Expect = 0.0
 Identities = 378/900 (42%), Positives = 494/900 (54%), Gaps = 143/900 (15%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220
           G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
                    S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 155 ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205

Query: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
           +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 206 VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259

Query: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 260 ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303

Query: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
           C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 304 CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363

Query: 461 ICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGS 520
            CS                                S L LRL  GG RC G VEV  +  
Sbjct: 364 TCSDG------------------------------SDLELRLRGGGSRCAGTVEVEIQRL 393

Query: 521 WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 580
            G VCD  W   +A+VVCRQLGCG A+           +    L    C+GNE+ LW C 
Sbjct: 394 LGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCK 453

Query: 581 HNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQG 640
           +  W    C H E+A + CSA +                          RLV G   C G
Sbjct: 454 NWQWGGLTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSG 489

Query: 641 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 700
           RVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G
Sbjct: 490 RVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEG 549

Query: 701 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRL 760
           HES+L  CP        C HS D GV+CS                            +RL
Sbjct: 550 HESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRL 585

Query: 761 VNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPI 820
           VNG   C GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG A+FG+G+G I
Sbjct: 586 VNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQI 645

Query: 821 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL- 879
                 C+G E ++  CP     +  C   + A VICS  QSQ      T  + N  +L 
Sbjct: 646 WRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQ------TLSSCNSSSLG 699

Query: 880 ----TVGSESSLA------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 929
               T+  ES++A      LRLVNGG RC GRVE+ + GSWGT+CDDSWD +DA+VVCRQ
Sbjct: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759

Query: 930 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           LGCG A++A G+A FG+G+GPI LD+++C+G ES +W C   GW   NC H EDAGVICS
Sbjct: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819



 Score =  661 bits (1705), Expect = 0.0
 Identities = 378/991 (38%), Positives = 510/991 (51%), Gaps = 153/991 (15%)

Query: 14  WGQVLSTGGWIPRTTDYASLIPSEVPLDTTV-----AEGSPFPSELTLESTVAEGSPISL 68
           WG V + G W   + +  S+I +++   T +     A  S     + ++     G+  +L
Sbjct: 72  WGTVCNNG-W---SMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESAL 127

Query: 69  ESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCD 128
                    + S    +     T ++GS+  L +RL  G   C GR+EI ++G WGTVCD
Sbjct: 128 WDCKHDGWGKHSNCTHQQDAGVTCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCD 185

Query: 129 DSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLS 188
           D+++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  
Sbjct: 186 DNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGK 245

Query: 189 HNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVE 248
           HNC H EDAGVICS                           + L+LRLV+G   C GR+E
Sbjct: 246 HNCDHAEDAGVICSKG-------------------------ADLSLRLVDGVTECSGRLE 280

Query: 249 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 308
           V ++G WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C GHE 
Sbjct: 281 VRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEP 340

Query: 309 YLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 368
            +W C H+ W  H C H+EDAGV CS                        S L LRL  G
Sbjct: 341 AVWQCKHHEWGKHYCNHNEDAGVTCS----------------------DGSDLELRLRGG 378

Query: 369 GDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIV 426
           G RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  + 
Sbjct: 379 GSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLF 438

Query: 427 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTIT 486
           L    C+G E+ LW C +  W    C H E+A + CSA                      
Sbjct: 439 LSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------- 477

Query: 487 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 546
                         RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  
Sbjct: 478 -------------PRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTV 524

Query: 547 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRS 606
           +   G A FG+G+G I  ++ +C G+ES+L  CP        C HS D GV+C    SR 
Sbjct: 525 VSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC----SRY 580

Query: 607 TPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVV 666
           T                     +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+
Sbjct: 581 T--------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVL 620

Query: 667 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV 726
           C+QL CG A+S PG ARFG+G+G I      C+G E ++  CP     +  C   + A V
Sbjct: 621 CQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASV 680

Query: 727 ICSASQSRPTPSPDT---WPTSRASTAGSESTLA------LRLVNGGDRCRGRVEVLYQG 777
           ICS +QS+   S ++    PT    T   ES +A      LRLVNGG RC GRVE+ ++G
Sbjct: 681 ICSGNQSQTLSSCNSSSLGPT--RPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEG 738

Query: 778 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837
           SWGT+CDD WD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G ES +W C
Sbjct: 739 SWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQC 798

Query: 838 PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897
             +GW   NC H EDAGVICS   S                L + SE+S         + 
Sbjct: 799 HSHGWGQQNCRHKEDAGVICSEFMS----------------LRLTSEAS--------REA 834

Query: 898 CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957
           C GR+EV Y G+WGTV   S       VVCRQLGC         +     S P+ +D+V+
Sbjct: 835 CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894

Query: 958 CSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 988
           C      LW CP   W        E+  + C
Sbjct: 895 CPKGPDTLWQCPSSPWEKRLASPSEETWITC 925



 Score =  659 bits (1700), Expect = 0.0
 Identities = 367/929 (39%), Positives = 481/929 (51%), Gaps = 150/929 (16%)

Query: 93   AEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 152
            ++G+D  L+LRLV+G   C GR+E+ ++G WGT+CDD WD+ DA V C+QLGC  A++A 
Sbjct: 259  SKGAD--LSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAI 316

Query: 153  GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRP 212
            G     +G G I LD V C GHE  +W C H+ W  H C H EDAGV CS          
Sbjct: 317  GRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS---------- 366

Query: 213  ESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVC 272
                         +GS+  L LRL  GG RC G VEV  +   G VCD  W   +A+VVC
Sbjct: 367  -------------DGSD--LELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVC 411

Query: 273  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVI 332
            RQLGCG A+           +    L    C+G+E+ LW C +  W    C H E+A + 
Sbjct: 412  RQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKIT 471

Query: 333  CSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 392
            CSA +                          RLV G   C GRVEV +  +WG++CD  +
Sbjct: 472  CSAHREP------------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDF 507

Query: 393  DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNC 452
                A+V+CR+L CG   S  G A FG+G+G I  ++ +C G+ES+L  CP        C
Sbjct: 508  SLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC 567

Query: 453  QHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGR 512
             HS D GV+CS                                    +RLVNG   C+GR
Sbjct: 568  SHSRDVGVVCSRYTE--------------------------------IRLVNGKTPCEGR 595

Query: 513  VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGN 572
            VE+   G+WG++C+  WD  DA+V+C+QL CG A+  PG ARFG+G+G I      C+G 
Sbjct: 596  VELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGT 655

Query: 573  ESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSR------STPRPDTWPT-SHASTAGSES 625
            E ++  CP     +  C   + A VICS  QS+      S+    T PT    S      
Sbjct: 656  EQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIE 715

Query: 626  SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 685
            S  LRLVNGG RC GRVE+ ++GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG
Sbjct: 716  SGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFG 775

Query: 686  QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 745
            +G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                
Sbjct: 776  EGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS---------------- 819

Query: 746  RASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGW 803
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871

Query: 804  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQ 863
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914

Query: 864  STPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDA 923
            ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVCDDSWD +DA
Sbjct: 915  ASPSEETWITCD-----------NKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDA 963

Query: 924  NVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED 983
             VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W    CGH ED
Sbjct: 964  QVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKED 1023

Query: 984  AGVICSATQINSTTTDWWHPTTTTTARPS 1012
            A V C+   +  T      P   TT R S
Sbjct: 1024 AAVNCTDISVQKT------PQKATTGRSS 1046



 Score =  624 bits (1609), Expect = e-178
 Identities = 350/893 (39%), Positives = 454/893 (50%), Gaps = 144/893 (16%)

Query: 363  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 423  GPIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSEDAGVICSAAHSWSTPSPGERDRTDT 481
            G I +D V C G ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 482  LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 541
                          S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL
Sbjct: 155  --------------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQL 200

Query: 542  GCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSA 601
             CG A+   G++ FG+GSGPI  DD+ C+GNES LW+C H GW  HNC H+EDAGVICS 
Sbjct: 201  ECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSK 260

Query: 602  AQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 661
                                   + L+LRLV+G   C GR+EV +QG WGT+CDD WD+ 
Sbjct: 261  G----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298

Query: 662  DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 721
            DA V C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+
Sbjct: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358

Query: 722  EDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGT 781
            EDAGV CS                        S L LRL  GG RC G VEV  Q   G 
Sbjct: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396

Query: 782  VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNG 841
            VCD  W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  
Sbjct: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQ 456

Query: 842  WLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGR 901
            W    C H+E+A + CSA +                            RLV G   C GR
Sbjct: 457  WGGLTCDHYEEAKITCSAHREP--------------------------RLVGGDIPCSGR 490

Query: 902  VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGN 961
            VEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G+
Sbjct: 491  VEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGH 550

Query: 962  ESYLWSCPHKGWLTHNCGHHEDAGVICSATQ----INSTTTDWWHPTTTTTARPSSNCGG 1017
            ES+L  CP        C H  D GV+CS       +N  T         T     S C  
Sbjct: 551  ESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNS 610

Query: 1018 FLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFD 1077
                                  KC   +    G R   G   +     H C+     + D
Sbjct: 611  HWDIEDAHVLC--------QQLKCGVALSTPGGARFGKGNGQIWRHMFH-CTGTEQHMGD 661

Query: 1078 ---GSLNSSL-----LLGKICNDTRQIFTSSYN-------RMTIHFRSDISFQNTGFLAW 1122
                +L +SL     +   IC+  +    SS N       R TI   S ++   +G    
Sbjct: 662  CPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG---- 717

Query: 1123 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182
                     LRLVN     G CAGRVEIYH G+WGT+CDDSW + +A VVCRQLGCG A+
Sbjct: 718  --------QLRLVN---GGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766

Query: 1183 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            +A G+A+FG G+GPI LD+++C+G ES +WQC + GW   NC H+EDAGVICS
Sbjct: 767  NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819



 Score =  613 bits (1581), Expect = e-175
 Identities = 364/1027 (35%), Positives = 495/1027 (48%), Gaps = 178/1027 (17%)

Query: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152

Query: 353  STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208

Query: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261

Query: 473  PGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 532
                                   + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ 
Sbjct: 262  -----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298

Query: 533  DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHS 592
            DA V C+QLGC  A+ A G     +G G I LD V C G+E  +W C H+ W  H C H+
Sbjct: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358

Query: 593  EDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 652
            EDAGV CS                        S L LRL  GG RC G VEV  Q   G 
Sbjct: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396

Query: 653  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 712
            VCD  W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  
Sbjct: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQ 456

Query: 713  WLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVE 772
            W    C H E+A + CSA +                          RLV G   C GRVE
Sbjct: 457  WGGLTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVE 492

Query: 773  VLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 832
            V +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES
Sbjct: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552

Query: 833  YLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLV 892
            +L  CP        C H  D GV+CS                              +RLV
Sbjct: 553  HLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------------------------IRLV 586

Query: 893  NGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 952
            NG   C GRVE+   G+WG++C+  WD  DA+V+C+QL CG A+S PG ARFG+G+G I 
Sbjct: 587  NGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIW 646

Query: 953  LDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ---INSTTTDWWHPTTTTTA 1009
                 C+G E ++  CP        C   + A VICS  Q   ++S  +    PT  T  
Sbjct: 647  RHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIP 706

Query: 1010 RPSS----------------NCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1052
              S+                 C G +  Y  G++ +    ++  ++A  V   ++  G  
Sbjct: 707  EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR-QLGCGEA 765

Query: 1053 INLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIH 1107
            IN   S     AH            G     + L ++ CN       Q  +  + +    
Sbjct: 766  INATGS-----AHF-----------GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCR 809

Query: 1108 FRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQ 1167
             + D     + F+          +LRL +  +S   CAGR+E+++ G WGTV   S +  
Sbjct: 810  HKEDAGVICSEFM----------SLRLTS-EASREACAGRLEVFYNGAWGTVGKSSMSET 858

Query: 1168 EAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHR 1227
               VVCRQLGC         +   + S P+ +D+V+C     TLWQC +  W     +  
Sbjct: 859  TVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPS 918

Query: 1228 EDAGVIC 1234
            E+  + C
Sbjct: 919  EETWITC 925



 Score =  427 bits (1098), Expect = e-119
 Identities = 223/513 (43%), Positives = 282/513 (54%), Gaps = 74/513 (14%)

Query: 484 TITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 538
           T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C
Sbjct: 30  TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVIC 89

Query: 539 RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGHSEDAGV 597
            QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H +DAGV
Sbjct: 90  NQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGV 149

Query: 598 ICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDS 657
            CS                        S+L +RL  GG+ C GR+E+ +QG WGTVCDD+
Sbjct: 150 TCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDN 187

Query: 658 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 717
           ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HN
Sbjct: 188 FNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHN 247

Query: 718 CGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG 777
           C H+EDAGVICS                        + L+LRLV+G   C GR+EV +QG
Sbjct: 248 CDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRLEVRFQG 285

Query: 778 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837
            WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C GHE  +W C
Sbjct: 286 EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQC 345

Query: 838 PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897
            H+ W  H C H+EDAGV CS                          S L LRL  GG R
Sbjct: 346 KHHEWGKHYCNHNEDAGVTCS------------------------DGSDLELRLRGGGSR 381

Query: 898 CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957
           C G VEV  +   G VCD  W   +A+VVCRQLGCG A+           +    L    
Sbjct: 382 CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS 441

Query: 958 CSGNESYLWSCPHKGWLTHNCGHHEDAGVICSA 990
           C+GNE+ LW C +  W    C H+E+A + CSA
Sbjct: 442 CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSA 474



 Score =  318 bits (815), Expect = 3e-86
 Identities = 180/439 (41%), Positives = 226/439 (51%), Gaps = 60/439 (13%)

Query: 43   TVAEGSPFPSELTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLAL 102
            T    S  PSE  + S +  G+    +S   S+    SL P+  T+    A        L
Sbjct: 665  TALGASLCPSE-QVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQL 719

Query: 103  RLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSG 162
            RLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+G
Sbjct: 720  RLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG 779

Query: 163  PIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPP 222
            PI LD+++C+G ES +W C  +GW   NC H EDAGVICS                    
Sbjct: 780  PIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS-------------------- 819

Query: 223  VPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
                     ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC   
Sbjct: 820  -------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK 872

Query: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
                  +     S P+ +D+V+C      LW CP + W                  +   
Sbjct: 873  GKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLA 915

Query: 341  TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
            +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA VV
Sbjct: 916  SPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVV 966

Query: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
            C+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA V
Sbjct: 967  CQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAV 1026

Query: 461  ICSAAHSWSTPSPGERDRT 479
             C+      TP      R+
Sbjct: 1027 NCTDISVQKTPQKATTGRS 1045



 Score =  130 bits (328), Expect = 8e-30
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029



 Score =  108 bits (271), Expect = 3e-23
 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 4/109 (3%)

Query: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
            +D  LRLV+  +    C+GRVE+     WGTVC++ W+++   V+C QLGC  A+ A G 
Sbjct: 47   TDKELRLVDGENK---CSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGW 103

Query: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH-NCNHREDAGVICS 1235
            A   +GSG I +D V C G ES LW C++ GW  H NC H++DAGV CS
Sbjct: 104  ANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1191
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639

Query: 1192 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1241
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425

Query: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1237
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475


>gi|44662834 CD163 antigen isoform a [Homo sapiens]
          Length = 1156

 Score =  721 bits (1862), Expect = 0.0
 Identities = 378/900 (42%), Positives = 494/900 (54%), Gaps = 143/900 (15%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220
           G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
                    S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 155 ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205

Query: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
           +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 206 VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259

Query: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 260 ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303

Query: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
           C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 304 CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363

Query: 461 ICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGS 520
            CS                                S L LRL  GG RC G VEV  +  
Sbjct: 364 TCSDG------------------------------SDLELRLRGGGSRCAGTVEVEIQRL 393

Query: 521 WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 580
            G VCD  W   +A+VVCRQLGCG A+           +    L    C+GNE+ LW C 
Sbjct: 394 LGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCK 453

Query: 581 HNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQG 640
           +  W    C H E+A + CSA +                          RLV G   C G
Sbjct: 454 NWQWGGLTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSG 489

Query: 641 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 700
           RVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G
Sbjct: 490 RVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEG 549

Query: 701 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRL 760
           HES+L  CP        C HS D GV+CS                            +RL
Sbjct: 550 HESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRL 585

Query: 761 VNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPI 820
           VNG   C GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG A+FG+G+G I
Sbjct: 586 VNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQI 645

Query: 821 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL- 879
                 C+G E ++  CP     +  C   + A VICS  QSQ      T  + N  +L 
Sbjct: 646 WRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQ------TLSSCNSSSLG 699

Query: 880 ----TVGSESSLA------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 929
               T+  ES++A      LRLVNGG RC GRVE+ + GSWGT+CDDSWD +DA+VVCRQ
Sbjct: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759

Query: 930 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           LGCG A++A G+A FG+G+GPI LD+++C+G ES +W C   GW   NC H EDAGVICS
Sbjct: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819



 Score =  661 bits (1705), Expect = 0.0
 Identities = 378/991 (38%), Positives = 510/991 (51%), Gaps = 153/991 (15%)

Query: 14  WGQVLSTGGWIPRTTDYASLIPSEVPLDTTV-----AEGSPFPSELTLESTVAEGSPISL 68
           WG V + G W   + +  S+I +++   T +     A  S     + ++     G+  +L
Sbjct: 72  WGTVCNNG-W---SMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESAL 127

Query: 69  ESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCD 128
                    + S    +     T ++GS+  L +RL  G   C GR+EI ++G WGTVCD
Sbjct: 128 WDCKHDGWGKHSNCTHQQDAGVTCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCD 185

Query: 129 DSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLS 188
           D+++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  
Sbjct: 186 DNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGK 245

Query: 189 HNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVE 248
           HNC H EDAGVICS                           + L+LRLV+G   C GR+E
Sbjct: 246 HNCDHAEDAGVICSKG-------------------------ADLSLRLVDGVTECSGRLE 280

Query: 249 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 308
           V ++G WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C GHE 
Sbjct: 281 VRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEP 340

Query: 309 YLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 368
            +W C H+ W  H C H+EDAGV CS                        S L LRL  G
Sbjct: 341 AVWQCKHHEWGKHYCNHNEDAGVTCS----------------------DGSDLELRLRGG 378

Query: 369 GDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIV 426
           G RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  + 
Sbjct: 379 GSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLF 438

Query: 427 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTIT 486
           L    C+G E+ LW C +  W    C H E+A + CSA                      
Sbjct: 439 LSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------- 477

Query: 487 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 546
                         RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  
Sbjct: 478 -------------PRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTV 524

Query: 547 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRS 606
           +   G A FG+G+G I  ++ +C G+ES+L  CP        C HS D GV+C    SR 
Sbjct: 525 VSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC----SRY 580

Query: 607 TPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVV 666
           T                     +RLVNG   C+GRVE+   G+WG++C+  WD  DA+V+
Sbjct: 581 T--------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVL 620

Query: 667 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV 726
           C+QL CG A+S PG ARFG+G+G I      C+G E ++  CP     +  C   + A V
Sbjct: 621 CQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASV 680

Query: 727 ICSASQSRPTPSPDT---WPTSRASTAGSESTLA------LRLVNGGDRCRGRVEVLYQG 777
           ICS +QS+   S ++    PT    T   ES +A      LRLVNGG RC GRVE+ ++G
Sbjct: 681 ICSGNQSQTLSSCNSSSLGPT--RPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEG 738

Query: 778 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837
           SWGT+CDD WD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G ES +W C
Sbjct: 739 SWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQC 798

Query: 838 PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897
             +GW   NC H EDAGVICS   S                L + SE+S         + 
Sbjct: 799 HSHGWGQQNCRHKEDAGVICSEFMS----------------LRLTSEAS--------REA 834

Query: 898 CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957
           C GR+EV Y G+WGTV   S       VVCRQLGC         +     S P+ +D+V+
Sbjct: 835 CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894

Query: 958 CSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 988
           C      LW CP   W        E+  + C
Sbjct: 895 CPKGPDTLWQCPSSPWEKRLASPSEETWITC 925



 Score =  659 bits (1700), Expect = 0.0
 Identities = 367/929 (39%), Positives = 481/929 (51%), Gaps = 150/929 (16%)

Query: 93   AEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 152
            ++G+D  L+LRLV+G   C GR+E+ ++G WGT+CDD WD+ DA V C+QLGC  A++A 
Sbjct: 259  SKGAD--LSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAI 316

Query: 153  GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRP 212
            G     +G G I LD V C GHE  +W C H+ W  H C H EDAGV CS          
Sbjct: 317  GRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS---------- 366

Query: 213  ESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVC 272
                         +GS+  L LRL  GG RC G VEV  +   G VCD  W   +A+VVC
Sbjct: 367  -------------DGSD--LELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVC 411

Query: 273  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVI 332
            RQLGCG A+           +    L    C+G+E+ LW C +  W    C H E+A + 
Sbjct: 412  RQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKIT 471

Query: 333  CSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 392
            CSA +                          RLV G   C GRVEV +  +WG++CD  +
Sbjct: 472  CSAHREP------------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDF 507

Query: 393  DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNC 452
                A+V+CR+L CG   S  G A FG+G+G I  ++ +C G+ES+L  CP        C
Sbjct: 508  SLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC 567

Query: 453  QHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGR 512
             HS D GV+CS                                    +RLVNG   C+GR
Sbjct: 568  SHSRDVGVVCSRYTE--------------------------------IRLVNGKTPCEGR 595

Query: 513  VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGN 572
            VE+   G+WG++C+  WD  DA+V+C+QL CG A+  PG ARFG+G+G I      C+G 
Sbjct: 596  VELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGT 655

Query: 573  ESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSR------STPRPDTWPT-SHASTAGSES 625
            E ++  CP     +  C   + A VICS  QS+      S+    T PT    S      
Sbjct: 656  EQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIE 715

Query: 626  SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 685
            S  LRLVNGG RC GRVE+ ++GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG
Sbjct: 716  SGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFG 775

Query: 686  QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 745
            +G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                
Sbjct: 776  EGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS---------------- 819

Query: 746  RASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGW 803
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871

Query: 804  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQ 863
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914

Query: 864  STPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDA 923
            ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVCDDSWD +DA
Sbjct: 915  ASPSEETWITCD-----------NKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDA 963

Query: 924  NVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED 983
             VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W    CGH ED
Sbjct: 964  QVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKED 1023

Query: 984  AGVICSATQINSTTTDWWHPTTTTTARPS 1012
            A V C+   +  T      P   TT R S
Sbjct: 1024 AAVNCTDISVQKT------PQKATTGRSS 1046



 Score =  624 bits (1609), Expect = e-178
 Identities = 350/893 (39%), Positives = 454/893 (50%), Gaps = 144/893 (16%)

Query: 363  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 423  GPIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSEDAGVICSAAHSWSTPSPGERDRTDT 481
            G I +D V C G ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 482  LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 541
                          S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL
Sbjct: 155  --------------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQL 200

Query: 542  GCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSA 601
             CG A+   G++ FG+GSGPI  DD+ C+GNES LW+C H GW  HNC H+EDAGVICS 
Sbjct: 201  ECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSK 260

Query: 602  AQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 661
                                   + L+LRLV+G   C GR+EV +QG WGT+CDD WD+ 
Sbjct: 261  G----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298

Query: 662  DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 721
            DA V C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+
Sbjct: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358

Query: 722  EDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGT 781
            EDAGV CS                        S L LRL  GG RC G VEV  Q   G 
Sbjct: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396

Query: 782  VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNG 841
            VCD  W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  
Sbjct: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQ 456

Query: 842  WLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGR 901
            W    C H+E+A + CSA +                            RLV G   C GR
Sbjct: 457  WGGLTCDHYEEAKITCSAHREP--------------------------RLVGGDIPCSGR 490

Query: 902  VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGN 961
            VEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G+
Sbjct: 491  VEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGH 550

Query: 962  ESYLWSCPHKGWLTHNCGHHEDAGVICSATQ----INSTTTDWWHPTTTTTARPSSNCGG 1017
            ES+L  CP        C H  D GV+CS       +N  T         T     S C  
Sbjct: 551  ESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNS 610

Query: 1018 FLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFD 1077
                                  KC   +    G R   G   +     H C+     + D
Sbjct: 611  HWDIEDAHVLC--------QQLKCGVALSTPGGARFGKGNGQIWRHMFH-CTGTEQHMGD 661

Query: 1078 ---GSLNSSL-----LLGKICNDTRQIFTSSYN-------RMTIHFRSDISFQNTGFLAW 1122
                +L +SL     +   IC+  +    SS N       R TI   S ++   +G    
Sbjct: 662  CPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG---- 717

Query: 1123 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182
                     LRLVN     G CAGRVEIYH G+WGT+CDDSW + +A VVCRQLGCG A+
Sbjct: 718  --------QLRLVN---GGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766

Query: 1183 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            +A G+A+FG G+GPI LD+++C+G ES +WQC + GW   NC H+EDAGVICS
Sbjct: 767  NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819



 Score =  613 bits (1581), Expect = e-175
 Identities = 364/1027 (35%), Positives = 495/1027 (48%), Gaps = 178/1027 (17%)

Query: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152

Query: 353  STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208

Query: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261

Query: 473  PGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 532
                                   + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ 
Sbjct: 262  -----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298

Query: 533  DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHS 592
            DA V C+QLGC  A+ A G     +G G I LD V C G+E  +W C H+ W  H C H+
Sbjct: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358

Query: 593  EDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 652
            EDAGV CS                        S L LRL  GG RC G VEV  Q   G 
Sbjct: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396

Query: 653  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 712
            VCD  W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  
Sbjct: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQ 456

Query: 713  WLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVE 772
            W    C H E+A + CSA +                          RLV G   C GRVE
Sbjct: 457  WGGLTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVE 492

Query: 773  VLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 832
            V +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES
Sbjct: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552

Query: 833  YLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLV 892
            +L  CP        C H  D GV+CS                              +RLV
Sbjct: 553  HLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------------------------IRLV 586

Query: 893  NGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 952
            NG   C GRVE+   G+WG++C+  WD  DA+V+C+QL CG A+S PG ARFG+G+G I 
Sbjct: 587  NGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIW 646

Query: 953  LDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ---INSTTTDWWHPTTTTTA 1009
                 C+G E ++  CP        C   + A VICS  Q   ++S  +    PT  T  
Sbjct: 647  RHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIP 706

Query: 1010 RPSS----------------NCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1052
              S+                 C G +  Y  G++ +    ++  ++A  V   ++  G  
Sbjct: 707  EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR-QLGCGEA 765

Query: 1053 INLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIH 1107
            IN   S     AH            G     + L ++ CN       Q  +  + +    
Sbjct: 766  INATGS-----AHF-----------GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCR 809

Query: 1108 FRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQ 1167
             + D     + F+          +LRL +  +S   CAGR+E+++ G WGTV   S +  
Sbjct: 810  HKEDAGVICSEFM----------SLRLTS-EASREACAGRLEVFYNGAWGTVGKSSMSET 858

Query: 1168 EAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHR 1227
               VVCRQLGC         +   + S P+ +D+V+C     TLWQC +  W     +  
Sbjct: 859  TVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPS 918

Query: 1228 EDAGVIC 1234
            E+  + C
Sbjct: 919  EETWITC 925



 Score =  427 bits (1098), Expect = e-119
 Identities = 223/513 (43%), Positives = 282/513 (54%), Gaps = 74/513 (14%)

Query: 484 TITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 538
           T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C
Sbjct: 30  TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVIC 89

Query: 539 RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGHSEDAGV 597
            QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H +DAGV
Sbjct: 90  NQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGV 149

Query: 598 ICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDS 657
            CS                        S+L +RL  GG+ C GR+E+ +QG WGTVCDD+
Sbjct: 150 TCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDN 187

Query: 658 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 717
           ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HN
Sbjct: 188 FNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHN 247

Query: 718 CGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG 777
           C H+EDAGVICS                        + L+LRLV+G   C GR+EV +QG
Sbjct: 248 CDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRLEVRFQG 285

Query: 778 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837
            WGT+CDD WD+ DA V C+QLGC  A++A G     +G G I LD V C GHE  +W C
Sbjct: 286 EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQC 345

Query: 838 PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897
            H+ W  H C H+EDAGV CS                          S L LRL  GG R
Sbjct: 346 KHHEWGKHYCNHNEDAGVTCS------------------------DGSDLELRLRGGGSR 381

Query: 898 CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957
           C G VEV  +   G VCD  W   +A+VVCRQLGCG A+           +    L    
Sbjct: 382 CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS 441

Query: 958 CSGNESYLWSCPHKGWLTHNCGHHEDAGVICSA 990
           C+GNE+ LW C +  W    C H+E+A + CSA
Sbjct: 442 CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSA 474



 Score =  318 bits (815), Expect = 3e-86
 Identities = 180/439 (41%), Positives = 226/439 (51%), Gaps = 60/439 (13%)

Query: 43   TVAEGSPFPSELTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLAL 102
            T    S  PSE  + S +  G+    +S   S+    SL P+  T+    A        L
Sbjct: 665  TALGASLCPSE-QVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQL 719

Query: 103  RLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSG 162
            RLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+G
Sbjct: 720  RLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG 779

Query: 163  PIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPP 222
            PI LD+++C+G ES +W C  +GW   NC H EDAGVICS                    
Sbjct: 780  PIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS-------------------- 819

Query: 223  VPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
                     ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC   
Sbjct: 820  -------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK 872

Query: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
                  +     S P+ +D+V+C      LW CP + W                  +   
Sbjct: 873  GKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLA 915

Query: 341  TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
            +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA VV
Sbjct: 916  SPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVV 966

Query: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
            C+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA V
Sbjct: 967  CQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAV 1026

Query: 461  ICSAAHSWSTPSPGERDRT 479
             C+      TP      R+
Sbjct: 1027 NCTDISVQKTPQKATTGRS 1045



 Score =  130 bits (328), Expect = 8e-30
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029



 Score =  108 bits (271), Expect = 3e-23
 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 4/109 (3%)

Query: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
            +D  LRLV+  +    C+GRVE+     WGTVC++ W+++   V+C QLGC  A+ A G 
Sbjct: 47   TDKELRLVDGENK---CSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGW 103

Query: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH-NCNHREDAGVICS 1235
            A   +GSG I +D V C G ES LW C++ GW  H NC H++DAGV CS
Sbjct: 104  ANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1191
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639

Query: 1192 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1241
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425

Query: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1237
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475


>gi|18152779 scavenger receptor cysteine rich domain containing,
           group B (4 domains) [Homo sapiens]
          Length = 575

 Score =  511 bits (1316), Expect = e-144
 Identities = 263/545 (48%), Positives = 318/545 (58%), Gaps = 39/545 (7%)

Query: 81  LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
           L+P  S L+ T     +    LRLV G  RC+GR+E+++ GSWG+VCDD WD  DANVVC
Sbjct: 41  LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96

Query: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
           RQLGCG A+  P    FGQG GPI LD+V C G E+ L  C   GW  HNC H ED  V+
Sbjct: 97  RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156

Query: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
           C    P      +    R +PP      +S  ++RLV G + C+GRVE+L+ G WGTVCD
Sbjct: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215

Query: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
           D W   DA VVCRQLGCG AM+A  NA FG G+G I+LD+V C G E  L +C   GW  
Sbjct: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275

Query: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354
           HNCGH EDAG +C                          SA    P PS +T   + A+ 
Sbjct: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335

Query: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
           A  + S  LRLV G   C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A  A G
Sbjct: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395

Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPG 474
              FG G GP++LD+V C+G E+ L  C H GW  HNC H EDAG +C+           
Sbjct: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQ 455

Query: 475 ERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 534
           +   T  +PT   P    G      LRLVNG  RC+GRVE+     WGTVCDD+WD   A
Sbjct: 456 DGSETTRVPT---PRPRDGH-----LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAA 507

Query: 535 NVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED 594
            V+CRQLGCG A+ APG A FG G GPI+LD+V+C G ES L  C H  W +HNC HSED
Sbjct: 508 GVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSED 567

Query: 595 AGVIC 599
           A V+C
Sbjct: 568 ASVLC 572



 Score =  509 bits (1312), Expect = e-144
 Identities = 258/518 (49%), Positives = 309/518 (59%), Gaps = 32/518 (6%)

Query: 500 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 559
           LRLV G  RC+GR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A+  P    FGQG 
Sbjct: 58  LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 560 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHAS 619
           GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C        P      +    
Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177

Query: 620 TA--GSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 677
           T     +S  ++RLV G + CQGRVE+L+ G WGTVCDD W   DA VVCRQLGCG AM+
Sbjct: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237

Query: 678 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVIC--------- 728
           A  NA FG G+G I+LD+V C G E  L +C   GW  HNCGH EDAG +C         
Sbjct: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297

Query: 729 -----------------SASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRV 771
                            SA+   P PS +T   + A+ A  + +  LRLV G   CRGRV
Sbjct: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357

Query: 772 EVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 831
           EVL+ G WGTVCDD WD  DA V CR+ GCG A+ A G   FG G GP++LD+V C+G E
Sbjct: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417

Query: 832 SYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP-RPDTWLTTNLPALTVGSESSLALR 890
           + L  C H GW  HNCGHHEDAG +C+  +      + D   TT +P           LR
Sbjct: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVP---TPRPRDGHLR 474

Query: 891 LVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 950
           LVNG  RC GRVE+     WGTVCDD+WD   A V+CRQLGCG A++APG A FG G GP
Sbjct: 475 LVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGP 534

Query: 951 IVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 988
           I+LD+V+C G ES L  C H  W  HNC H EDA V+C
Sbjct: 535 ILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  506 bits (1304), Expect = e-143
 Identities = 260/520 (50%), Positives = 313/520 (60%), Gaps = 24/520 (4%)

Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
           LRLV G  RCRGR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A+  P    FGQG 
Sbjct: 58  LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSA--PQSRPTPSPDTWPTSH 351
           GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C    P   PT    T     
Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177

Query: 352 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
            +    +S  ++RLV G + CQGRVE+L+ G WGTVCDD W   DA VVCRQLGCG A +
Sbjct: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237

Query: 412 APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS---W 468
           A  NA FG G+G I+LD+V C G E  L +C   GW  HNC H EDAG +C+        
Sbjct: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297

Query: 469 STPSPGERD----RTDTLPT------------ITLPASTVGSESSLALRLVNGGDRCQGR 512
           + PS   R+    +TD   T            +T  A   G +S   LRLV G   C+GR
Sbjct: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG-RLRLVGGPGPCRGR 356

Query: 513 VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGN 572
           VEVL+ G WGTVCDD WD  DA V CR+ GCG A+ A G   FG G GP++LD+V C+G 
Sbjct: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416

Query: 573 ESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTP-RPDTWPTSHASTAGSESSLALRL 631
           E+ L  C H GW  HNCGH EDAG +C+  +      + D   T+   T        LRL
Sbjct: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRL 475

Query: 632 VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 691
           VNG  RC+GRVE+     WGTVCDD+WD   A V+CRQLGCG A++APG A FG G GPI
Sbjct: 476 VNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPI 535

Query: 692 VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 731
           +LD+V+C G ES L  C H  W +HNC HSEDA V+C  S
Sbjct: 536 LLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575



 Score =  388 bits (997), Expect = e-107
 Identities = 199/392 (50%), Positives = 238/392 (60%), Gaps = 30/392 (7%)

Query: 629 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 688
           LRLV G  RC+GR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A+  P    FGQG 
Sbjct: 58  LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 689 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT-WPTSRA 747
           GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C   +  PT  P     TSRA
Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCD--EFLPTQPPTRKMLTSRA 175

Query: 748 ---STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 804
              +    +S  ++RLV G + C+GRVE+L+ G WGTVCDD W   DA VVCRQLGCG A
Sbjct: 176 PPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAA 235

Query: 805 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA----- 859
           M+A  NA FG G+G I+LD+V C G E  L +C   GW  HNCGHHEDAG +C+      
Sbjct: 236 MAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPT 295

Query: 860 --AQSQSTPRPDTWLTTNLPALTVGSESSLA-----------------LRLVNGGDRCRG 900
             A   S  R D    T+  A  VG + S                   LRLV G   CRG
Sbjct: 296 LTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRG 355

Query: 901 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960
           RVEVL+ G WGTVCDD WD  DA V CR+ GCG A+ A G   FG G GP++LD+V C+G
Sbjct: 356 RVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAG 415

Query: 961 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 992
            E+ L  C H GW  HNCGHHEDAG +C+  +
Sbjct: 416 TEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447



 Score =  270 bits (690), Expect = 9e-72
 Identities = 134/261 (51%), Positives = 163/261 (62%), Gaps = 11/261 (4%)

Query: 758  LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 817
            LRLV G  RCRGR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A+  P    FGQG 
Sbjct: 58   LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 818  GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLP 877
            GPI+LD+V C G E+ L  C   GW  HNC H+ED  V+C        P     LT+  P
Sbjct: 118  GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM-LTSRAP 176

Query: 878  ALTV-GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 936
              T+   +S  ++RLV G + C+GRVE+L+ G WGTVCDD W   DA VVCRQLGCG AM
Sbjct: 177  PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236

Query: 937  SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC-------- 988
            +A  NA FG G+G I+LD+V C G E  L +C   GW  HNCGHHEDAG +C        
Sbjct: 237  AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296

Query: 989  SATQINSTTTDW-WHPTTTTT 1008
            +A   ++T  DW W    + T
Sbjct: 297  TALPSSATREDWAWQTDPSAT 317



 Score =  132 bits (332), Expect = 3e-30
 Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%)

Query: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
            S+ ++RLV       LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A  N
Sbjct: 185  SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241

Query: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1236
            A+FG G+G I LD+V C G E  L  C++ GW  HNC H EDAG +C+G
Sbjct: 242  AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290



 Score =  129 bits (325), Expect = 2e-29
 Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%)

Query: 1127 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1186
            P D  LRLVN       C GRVE+Y G  WGTVCDD+W ++ A V+CRQLGCG+A++A G
Sbjct: 468  PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524

Query: 1187 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
             A+FG G GPI LD+V+C G ES L  C +  W +HNC+H EDA V+C
Sbjct: 525  EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  126 bits (317), Expect = 2e-28
 Identities = 52/95 (54%), Positives = 64/95 (67%)

Query: 1142 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1201
            G C GRVE+ H G WGTVCDD W   +A V CR+ GCG A+ A G  +FG G GP+ LD+
Sbjct: 351  GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410

Query: 1202 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1236
            V C+GTE+ L  C + GW  HNC H EDAG +C+G
Sbjct: 411  VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445



 Score =  121 bits (304), Expect = 5e-27
 Identities = 51/91 (56%), Positives = 63/91 (69%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
            C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+       FG G GPI LD+VE
Sbjct: 67   CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
            C G E+ L +C +RGW  HNC H ED  V+C
Sbjct: 127  CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score =  485 bits (1248), Expect = e-136
 Identities = 256/585 (43%), Positives = 318/585 (54%), Gaps = 105/585 (17%)

Query: 487 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 546
           L A+ VG ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A
Sbjct: 7   LLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGA 66

Query: 547 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSA----- 601
           + APG A FG+G+GP+ L ++ C GNE  L  C H GW +H C H EDAGV+C+      
Sbjct: 67  LAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVAN 126

Query: 602 ------------------------------------------AQSRSTPRPDTWPTSHAS 619
                                                     A  + +PRP    ++ A 
Sbjct: 127 SRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAP 186

Query: 620 --TAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 677
             T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A++
Sbjct: 187 LLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALA 246

Query: 678 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTP 737
           APG ARFG G+GP+ +DDV C G E  L  CP + W   NC HSEDAG++C+       P
Sbjct: 247 APGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------P 300

Query: 738 SPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCR 797
           +P                  LRL +G   C GR+EV + G WG+VCDD WD  DA V CR
Sbjct: 301 AP-----------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACR 343

Query: 798 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 857
           +LGCG A++APG A FG+GSGPI+LDD+RC G+E+ L  CP   W  H+C H EDAG +C
Sbjct: 344 ELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVC 403

Query: 858 SAA------------QSQSTPR-----PDTWLTTNLPALT--------------VGSES- 885
                           + STPR     P + +T+  P                  G E+ 
Sbjct: 404 DGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAG 463

Query: 886 SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA-PGNARF 944
           S  LRLV G  +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P   RF
Sbjct: 464 SPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRF 523

Query: 945 GQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           G G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+
Sbjct: 524 GWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  483 bits (1242), Expect = e-136
 Identities = 251/573 (43%), Positives = 314/573 (54%), Gaps = 98/573 (17%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           LRL +G   C GR+E+ + G WGTVCDD WD  DA V CRQLGCG A++APG A+FG+G+
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES------- 214
           GP+ L ++ C G+E  L  C H GW +H C H EDAGV+C A Q  +  R +S       
Sbjct: 80  GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC-AGQRVANSRDDSTSPLDGA 138

Query: 215 -WP---VRISP------------------------------------PVPTEGSESSLAL 234
            WP   + +SP                                    P+ T G+     L
Sbjct: 139 PWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERL 198

Query: 235 RLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSG 294
           RLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A++APG A+FG G+G
Sbjct: 199 RLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAG 258

Query: 295 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST 354
           P+ +DDV C G E  L  CP + W   NC HSEDAG++C+ P  R               
Sbjct: 259 PVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR--------------- 303

Query: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
                   LRL +G   C GR+EV + G WG+VCDD+WD  DA V CR+LGCG A +APG
Sbjct: 304 --------LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPG 355

Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPG 474
            A FG+GSGPI+LDD+RC G E+ L  CP   W  H+C H EDAG +C        P   
Sbjct: 356 GAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTA 415

Query: 475 ERDRTDTLP--TITLPASTVGSES------------------------SLALRLVNGGDR 508
             D  ++ P    + P ST+ S++                        S  LRLV G  +
Sbjct: 416 PTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSK 475

Query: 509 CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA-PGNARFGQGSGPIVLDDV 567
           C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P   RFG G+GPI LDDV
Sbjct: 476 CSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDV 535

Query: 568 RCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
            C G E+ L  CP   W  HNC H+ED GV C+
Sbjct: 536 GCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  476 bits (1224), Expect = e-133
 Identities = 256/601 (42%), Positives = 314/601 (52%), Gaps = 116/601 (19%)

Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A++APG 
Sbjct: 13  GIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGG 72

Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346
           A FG+G+GP+ L ++ C G+E  L  C H GW  H C H EDAGV+C+  +   +    T
Sbjct: 73  AFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDST 132

Query: 347 -------WP--------------TSHAS----------------------------TAGS 357
                  WP               +HA                             T G+
Sbjct: 133 SPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGA 192

Query: 358 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNAR 417
                LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A +APG AR
Sbjct: 193 PRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGAR 252

Query: 418 FGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERD 477
           FG G+GP+ +DDV C G E  L  CP + W   NC HSEDAG++C+       P+P    
Sbjct: 253 FGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------PAP---- 302

Query: 478 RTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 537
                                 LRL +G   C GR+EV + G WG+VCDD+WD  DA V 
Sbjct: 303 ---------------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVA 341

Query: 538 CRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGV 597
           CR+LGCG A+ APG A FG+GSGPI+LDD+RC GNE+ L  CP   W  H+C H EDAG 
Sbjct: 342 CRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGA 401

Query: 598 ICSAA------------QSRSTPR------PDTWPTSHASTAG----------------S 623
           +C                + STPR      P T  +    TAG                 
Sbjct: 402 VCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPE 461

Query: 624 ESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA-PGNA 682
             S  LRLV G  +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P   
Sbjct: 462 AGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAG 521

Query: 683 RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS-PDT 741
           RFG G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+      + S P +
Sbjct: 522 RFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFS 581

Query: 742 W 742
           W
Sbjct: 582 W 582



 Score =  475 bits (1223), Expect = e-133
 Identities = 256/597 (42%), Positives = 315/597 (52%), Gaps = 100/597 (16%)

Query: 352 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
           A+  G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A +
Sbjct: 9   AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68

Query: 412 APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC--------- 462
           APG A FG+G+GP+ L ++ C G E  L  C H GW +H C H EDAGV+C         
Sbjct: 69  APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128

Query: 463 --SAAHSWSTPSPG---ERDRTDTLPTIT---------------------------LPAS 490
             S +     P PG   E   +   P +T                            P  
Sbjct: 129 DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188

Query: 491 TVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAP 550
           T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A+ AP
Sbjct: 189 TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248

Query: 551 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRP 610
           G ARFG G+GP+ +DDV C G E  L  CP + W   NC HSEDAG++C+    R     
Sbjct: 249 GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR----- 303

Query: 611 DTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQL 670
                             LRL +G   C GR+EV + G WG+VCDD+WD  DA V CR+L
Sbjct: 304 ------------------LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACREL 345

Query: 671 GCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS- 729
           GCG A++APG A FG+GSGPI+LDD+RC G+E+ L  CP   W  H+C H EDAG +C  
Sbjct: 346 GCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDG 405

Query: 730 -----ASQSRPTPSPDTWPTSRAS------------TAGSESTLA--------------- 757
                   + PT S ++ P   AS            TAG     A               
Sbjct: 406 MPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSP 465

Query: 758 -LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA-PGNAQFGQ 815
            LRLV G  +C GR+EV +   WGTVCDD WD  D+ VVCR+LGCG      P   +FG 
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW 525

Query: 816 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQS-QSTPRPDTW 871
           G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+      S   P +W
Sbjct: 526 GAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSW 582



 Score =  365 bits (938), Expect = e-100
 Identities = 209/504 (41%), Positives = 266/504 (52%), Gaps = 80/504 (15%)

Query: 42  TTVAEGSPFPSELTLESTVAEGSPISLESTL-----ESTVAEGSLIPSE--STLESTVAE 94
           T+  +G+P+P  L LE + +   P+   +       ++   + S  P +  ST    +  
Sbjct: 132 TSPLDGAPWPG-LLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTT 190

Query: 95  GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154
           G+     LRLV+G  RC GR+E+ + G WGTVCDD WD  DA V CR+LGCG A++APG 
Sbjct: 191 GAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGG 250

Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214
           A FG G+GP+ +DDV C G E  L  CP + W   NC H EDAG++C+   P+       
Sbjct: 251 ARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR------- 303

Query: 215 WPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 274
                              LRL +G   C GR+EV + G WG+VCDD WD  DA V CR+
Sbjct: 304 -------------------LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRE 344

Query: 275 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           LGCG A++APG A FG+GSGPI+LDD+RC G+E+ L  CP   W  H+C H EDAG +C 
Sbjct: 345 LGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCD 404

Query: 335 ------APQSRPTPSPDTWPTSHAS------------TAG----------------SESS 360
                  P + PT S ++ P   AS            TAG                   S
Sbjct: 405 GMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGS 464

Query: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA-PGNARFG 419
             LRLV G  +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P   RFG
Sbjct: 465 PQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFG 524

Query: 420 QGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC---------SAAHSWST 470
            G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C         S   SWS 
Sbjct: 525 WGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSWSW 584

Query: 471 PSPGERDRTDTLP--TITLPASTV 492
                RDR   LP    T P+++V
Sbjct: 585 IPGLGRDRDAWLPGELATKPSASV 608



 Score =  348 bits (894), Expect = 2e-95
 Identities = 209/578 (36%), Positives = 268/578 (46%), Gaps = 105/578 (18%)

Query: 747  ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 806
            A+  G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A++
Sbjct: 9    AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68

Query: 807  APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA------- 859
            APG A FG+G+GP+ L ++ C G+E  L  C H GW +H C H EDAGV+C+        
Sbjct: 69   APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128

Query: 860  ----------------------------------------AQSQSTPRPDTWLTTNLPAL 879
                                                    A  + +PRP    +T  P L
Sbjct: 129  DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188

Query: 880  TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 939
            T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A++AP
Sbjct: 189  TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248

Query: 940  GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT-------- 991
            G ARFG G+GP+ +DDV C G E  L  CP   W   NC H EDAG++C+          
Sbjct: 249  GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLAD 308

Query: 992  ---------------QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYP 1036
                           +  S   D W       A     CGG L    G F          
Sbjct: 309  GPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIIL 368

Query: 1037 NNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF--DYVEIFDGSLNSSLLLGKICNDTR 1094
            ++ +C        G    L F   +    H+C    D   + DG     + LG +     
Sbjct: 369  DDLRC-------RGNETALRFCPARPWGQHDCHHREDAGAVCDG-----MPLGYVPPTAP 416

Query: 1095 QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-------------LRLVNLNSSY 1141
                +S  R                 A  +  P+  T             LRLV   S  
Sbjct: 417  TDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSK- 475

Query: 1142 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG---RAVSALGNAYFGSGSGPIT 1198
              C+GR+E++H   WGTVCDDSW ++++ VVCR+LGCG   +   A G   FG G+GPI 
Sbjct: 476  --CSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGR--FGWGAGPIW 531

Query: 1199 LDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1236
            LDDV C GTE++L  C    W  HNC H ED GV C+G
Sbjct: 532  LDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTG 569



 Score =  143 bits (361), Expect = 1e-33
 Identities = 64/128 (50%), Positives = 83/128 (64%)

Query: 876  LPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 935
            L A  VG ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A
Sbjct: 7    LLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGA 66

Query: 936  MSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINS 995
            ++APG A FG+G+GP+ L ++ C GNE  L  C H+GW  H C H EDAGV+C+  ++ +
Sbjct: 67   LAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVAN 126

Query: 996  TTTDWWHP 1003
            +  D   P
Sbjct: 127  SRDDSTSP 134



 Score =  138 bits (348), Expect = 4e-32
 Identities = 78/198 (39%), Positives = 102/198 (51%), Gaps = 9/198 (4%)

Query: 23  WIPRTTDYASLIPS---EVPLDTTVAEGSPFPSELTLESTVAEGSPISLESTLESTVAEG 79
           W   TT  A+L P    E    T     +  P E+T EST+      SLE + E  + EG
Sbjct: 692 WTSHTT--ATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAE--IPEG 747

Query: 80  SL-IPSESTLESTVAEGSDSGL-ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDAN 137
           S   P +     +V+   +SGL  +RL +G  RC GR+E+ + G WGTVCDD+WD  DA 
Sbjct: 748 SPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807

Query: 138 VVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDA 197
           V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H ED 
Sbjct: 808 VACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDV 867

Query: 198 GVICSAAQPQSTLRPESW 215
           G+ C+         P +W
Sbjct: 868 GLTCTGYTDYDDYPPWTW 885



 Score =  138 bits (347), Expect = 5e-32
 Identities = 65/146 (44%), Positives = 80/146 (54%), Gaps = 1/146 (0%)

Query: 611 DTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQL 670
           D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA V C +L
Sbjct: 754 DPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWEL 813

Query: 671 GCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSA 730
           GCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H ED G+ C+ 
Sbjct: 814 GCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873

Query: 731 SQSRPTPSPDTW-PTSRASTAGSEST 755
                   P TW PTSR   A   +T
Sbjct: 874 YTDYDDYPPWTWDPTSREDLAKGTTT 899



 Score =  137 bits (344), Expect = 1e-31
 Identities = 72/187 (38%), Positives = 91/187 (48%), Gaps = 14/187 (7%)

Query: 336 PQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395
           P+  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD+WD  
Sbjct: 745 PEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLR 804

Query: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455
           DA V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H 
Sbjct: 805 DATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHE 864

Query: 456 EDAGVICSAAHSWSTPSPGERDRTDT-----------LPTITLPASTV---GSESSLALR 501
           ED G+ C+    +    P   D T             +P  TLP  T    GS S    R
Sbjct: 865 EDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIRR 924

Query: 502 LVNGGDR 508
           L + G +
Sbjct: 925 LPDTGSK 931



 Score =  136 bits (342), Expect = 2e-31
 Identities = 63/143 (44%), Positives = 85/143 (59%), Gaps = 7/143 (4%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
            CAGR+E++HGG WGTVCDD W +++A V CRQLGCG A++A G A+FG G+GP+ L ++ 
Sbjct: 29   CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAGPVWLSELA 88

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQ 1263
            C G E  L  C +RGW +H C+H EDAGV+C+G  ++      + T P       G L +
Sbjct: 89   CRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRD--DSTSPLDGAPWPGLLLE 146

Query: 1264 PSGDFSSPFY-----PGNYPNNA 1281
             S     P       P   P NA
Sbjct: 147  LSPSTEEPLVTHAPRPAGNPQNA 169



 Score =  136 bits (342), Expect = 2e-31
 Identities = 63/155 (40%), Positives = 81/155 (52%)

Query: 732 QSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTND 791
           +  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD WD  D
Sbjct: 746 EGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRD 805

Query: 792 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 851
           A V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H E
Sbjct: 806 ATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEE 865

Query: 852 DAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESS 886
           D G+ C+         P TW  T+   L  G+ ++
Sbjct: 866 DVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTA 900



 Score =  135 bits (341), Expect = 3e-31
 Identities = 56/101 (55%), Positives = 73/101 (72%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
            CAGR+E++HGG WG+VCDD+W +++A V CR+LGCG A++A G A+FG GSGPI LDD+ 
Sbjct: 313  CAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLR 372

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAP 1244
            C G E+ L  C  R W  H+C+HREDAG +C G  L    P
Sbjct: 373  CRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPP 413



 Score =  133 bits (334), Expect = 2e-30
 Identities = 63/137 (45%), Positives = 75/137 (54%), Gaps = 1/137 (0%)

Query: 220 SPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
           SP V T G      +RL +G +RC GR+EV + G WGTVCDD WD  DA V C +LGCG 
Sbjct: 758 SPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGK 817

Query: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
                G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H ED G+ C+     
Sbjct: 818 VRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDY 877

Query: 340 PTPSPDTW-PTSHASTA 355
               P TW PTS    A
Sbjct: 878 DDYPPWTWDPTSREDLA 894



 Score =  132 bits (332), Expect = 3e-30
 Identities = 62/140 (44%), Positives = 77/140 (55%), Gaps = 1/140 (0%)

Query: 483 PTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 542
           P  +   ST G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA V C +LG
Sbjct: 755 PAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELG 814

Query: 543 CGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAA 602
           CG      G   +G G+GPI LDD+ C G+E+ L  CP   W  HNC H ED G+ C+  
Sbjct: 815 CGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGY 874

Query: 603 QSRSTPRPDTW-PTSHASTA 621
                  P TW PTS    A
Sbjct: 875 TDYDDYPPWTWDPTSREDLA 894



 Score =  131 bits (330), Expect = 5e-30
 Identities = 64/135 (47%), Positives = 83/135 (61%), Gaps = 10/135 (7%)

Query: 1127 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1186
            P    LRLV   S    CAGR+E++HGG WGTVCDD W +++A V CR+LGCG A++A G
Sbjct: 193  PRQERLRLV---SGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPG 249

Query: 1187 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL 1246
             A FG G+GP+ +DDV C G E  L  C    W   NC+H EDAG++C+G     PAP L
Sbjct: 250  GARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG-----PAPRL 304

Query: 1247 NITRPNTDYSCGGFL 1261
             +   +  + C G L
Sbjct: 305  RLA--DGPHGCAGRL 317



 Score =  128 bits (322), Expect = 4e-29
 Identities = 61/138 (44%), Positives = 76/138 (55%), Gaps = 8/138 (5%)

Query: 880  TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 939
            T G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA V C +LGCG      
Sbjct: 763  TTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV 822

Query: 940  GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTD 999
            G   +G G+GPI LDD+ C G+E+ L  CP   W  HNC H ED G+ C+          
Sbjct: 823  GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPP 882

Query: 1000 W-WHPTT-------TTTA 1009
            W W PT+       TTTA
Sbjct: 883  WTWDPTSREDLAKGTTTA 900



 Score =  122 bits (307), Expect = 2e-27
 Identities = 50/112 (44%), Positives = 73/112 (65%)

Query: 1125 SFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184
            S   ++ L  V L      CAGR+E++H G WGTVCDD+W +++A V C +LGCG+    
Sbjct: 762  STTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPR 821

Query: 1185 LGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1236
            +G  ++G G+GPI LDD+ C G+E++L  C +  W  HNC+H ED G+ C+G
Sbjct: 822  VGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873


>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 343

 Score =  481 bits (1239), Expect = e-135
 Identities = 233/294 (79%), Positives = 243/294 (82%), Gaps = 25/294 (8%)

Query: 490 STVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 549
           S VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 550 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPR 609
           PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS    R+  R
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 610 PDTWPTSH-ASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCR 668
           P +WP+    S  G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCR
Sbjct: 128 PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 669 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVIC 728
           QLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGH EDAGVIC
Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 729 SASQS-----RPTPSP-----------------DTWPTSRA--STAGSESTLAL 758
           S S +     RP   P                 DT PT  A  + AGS +T+A+
Sbjct: 248 SGSWAVAGPRRPQEMPGLARAQDPLFWMMCAAQDTSPTCGAAPTMAGSPTTVAI 301



 Score =  468 bits (1203), Expect = e-131
 Identities = 213/250 (85%), Positives = 225/250 (90%), Gaps = 1/250 (0%)

Query: 619 STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 678
           S  GSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAM A
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 679 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS 738
           PGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGHSEDAGVICS    R    
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 739 PDTWPTS-RASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCR 797
           P +WP+    S  G ES+LALRLVNGGDRC+GRVEVLY+GSWGTVCDD WDTNDANVVCR
Sbjct: 128 PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 798 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 857
           QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHEDAGVIC
Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 858 SAAQSQSTPR 867
           S + + + PR
Sbjct: 248 SGSWAVAGPR 257



 Score =  461 bits (1185), Expect = e-129
 Identities = 212/248 (85%), Positives = 222/248 (89%), Gaps = 3/248 (1%)

Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           GSESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWAM APGN
Sbjct: 11  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 70

Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346
           A+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNCGHSEDAGVICS    R    P +
Sbjct: 71  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRS 130

Query: 347 WPTSH-ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLG 405
           WP+    S  G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT+DANVVCRQLG
Sbjct: 131 WPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 190

Query: 406 CGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA 465
           CGWATSAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNC H EDAGVICS  
Sbjct: 191 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSG- 249

Query: 466 HSWSTPSP 473
            SW+   P
Sbjct: 250 -SWAVAGP 256



 Score =  457 bits (1175), Expect = e-128
 Identities = 218/294 (74%), Positives = 236/294 (80%), Gaps = 28/294 (9%)

Query: 95  GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154
           GS+S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM APGN
Sbjct: 11  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 70

Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214
           A FGQGSGPI LDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS   P++ +RP S
Sbjct: 71  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRS 130

Query: 215 WPVR-ISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCR 273
           WP R +  P+   G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDTNDANVVCR
Sbjct: 131 WPSRFLCSPI---GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 274 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVIC 333
           QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP+NGWL+HNCGH EDAGVIC
Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 334 SA---------PQSRP-------------TPSPDTWPTSHA--STAGSESSLAL 363
           S          PQ  P               + DT PT  A  + AGS +++A+
Sbjct: 248 SGSWAVAGPRRPQEMPGLARAQDPLFWMMCAAQDTSPTCGAAPTMAGSPTTVAI 301



 Score =  454 bits (1169), Expect = e-127
 Identities = 206/244 (84%), Positives = 221/244 (90%), Gaps = 1/244 (0%)

Query: 748 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 807
           S  GSES+LALRLVNGGDRC+GRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWAM A
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 808 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 867
           PGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS    ++  R
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 868 PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVC 927
           P +W +  L    +G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDDSWDTNDANVVC
Sbjct: 128 PRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 186

Query: 928 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVI 987
           RQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+ GWL+HNCGHHEDAGVI
Sbjct: 187 RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 246

Query: 988 CSAT 991
           CS +
Sbjct: 247 CSGS 250



 Score =  450 bits (1157), Expect = e-126
 Identities = 213/257 (82%), Positives = 222/257 (86%), Gaps = 7/257 (2%)

Query: 353 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412
           S  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT+DANVVCRQLGCGWA  A
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 413 PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472
           PGNARFGQGSGPIVLDDVRCSG ESYLWSCPHNGWLSHNC HSEDAGVICS         
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGG------P 121

Query: 473 PGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 532
           P    R  + P+  L  S +G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN
Sbjct: 122 PRTPIRPRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 180

Query: 533 DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHS 592
           DANVVCRQLGCGWA  APGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNCGH 
Sbjct: 181 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHH 240

Query: 593 EDAGVICSAAQSRSTPR 609
           EDAGVICS + + + PR
Sbjct: 241 EDAGVICSGSWAVAGPR 257



 Score =  156 bits (394), Expect = 2e-37
 Identities = 73/110 (66%), Positives = 78/110 (70%), Gaps = 3/110 (2%)

Query: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
            S   LRLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A SA GN
Sbjct: 144  SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 200

Query: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1237
            A FG GSGPI LDDV CSG ES LW C N GW SHNC H EDAGVICSG+
Sbjct: 201  ARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250



 Score =  155 bits (393), Expect = 2e-37
 Identities = 85/153 (55%), Positives = 92/153 (60%), Gaps = 11/153 (7%)

Query: 1118 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLG 1177
            GFL       S   LRLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLG
Sbjct: 4    GFLFSPVGSESSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 60

Query: 1178 CGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1237
            CG A+ A GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG 
Sbjct: 61   CGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGG 120

Query: 1238 HLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSS 1270
               TP       RP +  S   FL  P G  SS
Sbjct: 121  PPRTP------IRPRSWPS--RFLCSPIGPESS 145


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score =  356 bits (913), Expect = 1e-97
 Identities = 196/490 (40%), Positives = 248/490 (50%), Gaps = 59/490 (12%)

Query: 499 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 558
           ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G   +A      G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 559 SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHA 618
             PI   +VRC G+E  +  C  + W    C     A V CS +   + P          
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278

Query: 619 STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 678
                     +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 279 ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329

Query: 679 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS 738
              A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 330 WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382

Query: 739 PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 798
            D                 +RL  G     GR+EV Y+G WGTVCDD W   +  VVCRQ
Sbjct: 383 TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427

Query: 799 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 858
           LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 428 LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486

Query: 859 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 918
                               L++G      +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 487 PGGEGHR-------------LSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529

Query: 919 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 978
              DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C  +    HNC
Sbjct: 530 TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589

Query: 979 GHHEDAGVIC 988
            H EDAGVIC
Sbjct: 590 RHSEDAGVIC 599



 Score =  355 bits (910), Expect = 3e-97
 Identities = 199/499 (39%), Positives = 246/499 (49%), Gaps = 68/499 (13%)

Query: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
           ++RL  G    +G VE+   G WGTVC   WD +DA+V+C QL  G    A    + G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220
             PI   +VRC G E  +  C  + W    C     A V CS +                
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274

Query: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
           P  P         +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG    
Sbjct: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326

Query: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       
Sbjct: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC------- 379

Query: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
           TP  D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VV
Sbjct: 380 TPLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424

Query: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
           CRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  +
Sbjct: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483

Query: 461 ICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGS 520
            C           GE  R                     +RL++G ++ +GRVEV   G 
Sbjct: 484 ACYPG--------GEGHRLSL---------------GFPVRLMDGENKKEGRVEVFINGQ 520

Query: 521 WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 580
           WGT+CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C 
Sbjct: 521 WGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCI 580

Query: 581 HNGWLSHNCGHSEDAGVIC 599
                 HNC HSEDAGVIC
Sbjct: 581 KQDIGRHNCRHSEDAGVIC 599



 Score =  354 bits (908), Expect = 5e-97
 Identities = 200/498 (40%), Positives = 249/498 (50%), Gaps = 69/498 (13%)

Query: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421
           ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDT 481
             PI   +VRC G E  +  C  + W    C     A V CS +H               
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG-------------- 274

Query: 482 LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 541
            PT  +            +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQL
Sbjct: 275 -PTFPI------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQL 321

Query: 542 GCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSA 601
           G      A   A FG+GSGP++LD+VRC+GNE  +  CP + W  HNCGH EDAGV C  
Sbjct: 322 GLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-- 379

Query: 602 AQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 661
                TP  D                 +RL  G    +GR+EV Y+G WGTVCDD W   
Sbjct: 380 -----TPLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTEL 419

Query: 662 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 721
           +  VVCRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H 
Sbjct: 420 NTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHR 478

Query: 722 EDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLA--LRLVNGGDRCRGRVEVLYQGSW 779
           ED  + C             +P       G   +L   +RL++G ++  GRVEV   G W
Sbjct: 479 EDVSIAC-------------YPGGE----GHRLSLGFPVRLMDGENKKEGRVEVFINGQW 521

Query: 780 GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPH 839
           GT+CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C  
Sbjct: 522 GTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIK 581

Query: 840 NGWLSHNCGHHEDAGVIC 857
                HNC H EDAGVIC
Sbjct: 582 QDIGRHNCRHSEDAGVIC 599



 Score =  261 bits (666), Expect = 5e-69
 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%)

Query: 757  ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 816
            ++RL  G +   G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 817  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 876
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278

Query: 877  PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 936
                        +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327

Query: 937  SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 996
             A   A FG+GSGP++LD+VRC+GNE  +  CP   W  HNCGH EDAGV C+       
Sbjct: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380

Query: 997  TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1052
                  P T    R      S+ G    Y  G + +     +   N   V          
Sbjct: 381  ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426

Query: 1053 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1111
              LGF    +  A+H         F+ S     L    C+     F     R     R D
Sbjct: 427  -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474

Query: 1112 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1166
             S +    +A Y   P     RL     V L        GRVE++  G WGT+CDD WT 
Sbjct: 475  CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531

Query: 1167 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1226
            ++A V+CRQLG      A   AYFG G GPI +D+V+C+G E +L  C  +    HNC H
Sbjct: 532  KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591

Query: 1227 REDAGVIC 1234
             EDAGVIC
Sbjct: 592  SEDAGVIC 599



 Score =  149 bits (375), Expect = 3e-35
 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%)

Query: 888  ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 947
            ++RL  G +   G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 948  SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1007
              PI   +VRC G+E  +  C    W    C     A V CS +   +       P    
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282

Query: 1008 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1067
                S + G    Y +G + +     +   +A+ +            LG S +  +A H 
Sbjct: 283  AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332

Query: 1068 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1122
              F       G  +  ++L ++ C        Q   SS+       + D     T     
Sbjct: 333  AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382

Query: 1123 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182
                 +D  +RL     S+    GR+E+Y+ G WGTVCDD WT     VVCRQLG     
Sbjct: 383  -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434

Query: 1183 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1238
             A  N +F   +GPI LDDV CSG E+   QC  R W  H+C+HRED  + C     G+ 
Sbjct: 435  QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493

Query: 1239 LSTPAP 1244
            LS   P
Sbjct: 494  LSLGFP 499



 Score =  112 bits (280), Expect = 3e-24
 Identities = 50/103 (48%), Positives = 66/103 (64%)

Query: 99  GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158
           G  +RL++G+ + +GRVE+   G WGT+CDD W   DA V+CRQLG      A   A+FG
Sbjct: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556

Query: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201
           +G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599


>gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]
          Length = 607

 Score =  296 bits (759), Expect = 9e-80
 Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%)

Query: 1247 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 1305
            NI+ PN    CGG+L    G F+SP YP  +P  A CVW I+V+ +Y++ + F+++ LE 
Sbjct: 148  NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203

Query: 1306 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 1364
               C +D++ ++DGP  +S LI +VC     +F SSSN +++   +D++ + RGF A Y 
Sbjct: 204  DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263

Query: 1365 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 1422
            S  + + ++T+L C  + M+  +S+SYL++   + ++L +        CRP+++ N+V F
Sbjct: 264  SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318

Query: 1423 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 1480
            ++P +GCGT ++ ++ +I Y+N +T  A+ +  +I R+  L+I V C M  N+ V+ +YI
Sbjct: 319  SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378

Query: 1481 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 1540
              D +  + N +       G ++ +++ + S+SF   +   PYYVDLNQ L+VQ  +  S
Sbjct: 379  TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431

Query: 1541 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 1600
            D  L +F+DTC ASP S DF S TYDLI+SGC RD+T   Y        RF+F AF FL 
Sbjct: 432  DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489

Query: 1601 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 1652
               SVYL+CK+++C + D  SRC +GCV RSKRD+ SY+ K D ++GPI+L+
Sbjct: 490  SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)

Query: 1014 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1073
            NCGG+L    G+F+SP+YP  +P  A CVW I+V   Y+I L F  + LE    C FD++
Sbjct: 153  NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212

Query: 1074 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1133
             I+DG   +S L+G++C      F SS N +T+   +D +    GF A Y S  ++    
Sbjct: 213  AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268

Query: 1134 LVNLNSSYGLCA 1145
              N+N++   C+
Sbjct: 269  --NINTTSLTCS 278



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%)

Query: 1283 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 1338
            C W IE   N  + +IF  VQL+  G C  + I+VFDG   + PL+ +VC  +     F 
Sbjct: 58   CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117

Query: 1339 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 1368
            SSS+ ++ + ++D + I R  F   Y+ SP+
Sbjct: 118  SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)

Query: 1041 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1098
            C W IE      I + FS ++L+   +C  + +++FDG+ ++  LLG++C  ND   +F 
Sbjct: 58   CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117

Query: 1099 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1128
            SS + +T    +D +  Q T F+ +Y   P+
Sbjct: 118  SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148


>gi|5174411 CD5 molecule-like [Homo sapiens]
          Length = 347

 Score =  269 bits (688), Expect = 1e-71
 Identities = 147/371 (39%), Positives = 186/371 (50%), Gaps = 50/371 (13%)

Query: 625 SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 684
           S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A   P    +
Sbjct: 20  SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 685 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT 741
               +    +++  V C+G E  L  C       ++C H EDAG  C   +S  +P P+ 
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 742 WPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGC 801
                           +RL +G   C+GRVEV +Q  W TVC   W    A VVCRQLGC
Sbjct: 137 ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181

Query: 802 GWAMSAPGNA-QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAA 860
           G A+       +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C   
Sbjct: 182 GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238

Query: 861 QSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDT 920
                                  E    LRLV G + C GR+EVL++G WG+VCDD+W  
Sbjct: 239 -----------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGE 275

Query: 921 NDANVVCRQLGCGWAMSAPGNAR--FGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 978
            +  VVC+QLGCG ++S     R  +G G G I LD+VRCSG E  L  C H+ W  H+C
Sbjct: 276 KEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDC 335

Query: 979 GHHEDAGVICS 989
            H ED  VICS
Sbjct: 336 THQEDVAVICS 346



 Score =  267 bits (683), Expect = 6e-71
 Identities = 147/377 (38%), Positives = 185/377 (49%), Gaps = 56/377 (14%)

Query: 359 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF 418
           S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A+  P    +
Sbjct: 20  SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 419 ---GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGE 475
               +    +++  V C+G E  L  C       ++C H EDAG  C    S  +P P  
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 476 RDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 535
                                   +RL +G   C+GRVEV ++  W TVC   W    A 
Sbjct: 137 -----------------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAK 173

Query: 536 VVCRQLGCGWAMLAPGNA-RFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED 594
           VVCRQLGCG A+L      +   G  PI L  + CSG E+ L  CP   W  + C H ED
Sbjct: 174 VVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDED 233

Query: 595 AGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 654
             V C                        E    LRLV G + C GR+EVL++G WG+VC
Sbjct: 234 TWVEC------------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVC 269

Query: 655 DDSWDTNDANVVCRQLGCGWAMSAPGNAR--FGQGSGPIVLDDVRCSGHESYLWSCPHNG 712
           DD+W   +  VVC+QLGCG ++S     R  +G G G I LD+VRCSG E  L  C H  
Sbjct: 270 DDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRF 329

Query: 713 WLSHNCGHSEDAGVICS 729
           W  H+C H ED  VICS
Sbjct: 330 WGFHDCTHQEDVAVICS 346



 Score =  265 bits (677), Expect = 3e-70
 Identities = 146/377 (38%), Positives = 183/377 (48%), Gaps = 56/377 (14%)

Query: 230 SSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF 289
           S   +RLV G  RC GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A   P    +
Sbjct: 20  SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 290 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346
               +    +++  V C+G E  L  C       ++C H EDAG  C  P+S  +P P+ 
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 347 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGC 406
                           +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGC
Sbjct: 137 ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181

Query: 407 GWATSAPGNA-RFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA 465
           G A        +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C   
Sbjct: 182 GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238

Query: 466 HSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 525
                                        E    LRLV G + C GR+EVL++G WG+VC
Sbjct: 239 -----------------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVC 269

Query: 526 DDSWDTNDANVVCRQLGCGWAMLAPGNAR--FGQGSGPIVLDDVRCSGNESYLWSCPHNG 583
           DD+W   +  VVC+QLGCG ++      R  +G G G I LD+VRCSG E  L  C H  
Sbjct: 270 DDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRF 329

Query: 584 WLSHNCGHSEDAGVICS 600
           W  H+C H ED  VICS
Sbjct: 330 WGFHDCTHQEDVAVICS 346



 Score =  262 bits (670), Expect = 2e-69
 Identities = 148/368 (40%), Positives = 185/368 (50%), Gaps = 51/368 (13%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWF---G 158
           +RLV G  RC+GRVE+  +G WGTVCDD WD  D  V+CR+LGCG A   P    +    
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVR 218
           +    + +  V C+G E  L  C       ++C H EDAG  C    P+S+         
Sbjct: 84  EKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCE--NPESSF-------- 131

Query: 219 ISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCG 278
              PVP EG      +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGCG
Sbjct: 132 --SPVP-EG------VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCG 182

Query: 279 WAMSAPGNA-QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQ 337
            A+       +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C  P 
Sbjct: 183 RAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDP- 241

Query: 338 SRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDA 397
                                    LRLV G + C GR+EVL++G WG+VCDD+W   + 
Sbjct: 242 -----------------------FDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKED 278

Query: 398 NVVCRQLGCGWATSAPGNAR--FGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455
            VVC+QLGCG + S     R  +G G G I LD+VRCSG E  L  C H  W  H+C H 
Sbjct: 279 QVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQ 338

Query: 456 EDAGVICS 463
           ED  VICS
Sbjct: 339 EDVAVICS 346



 Score =  114 bits (286), Expect = 6e-25
 Identities = 54/107 (50%), Positives = 74/107 (69%), Gaps = 5/107 (4%)

Query: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA--LGNAY 1189
            LRLV  ++   LC+GR+E+ H G WG+VCDD+W  +E +VVC+QLGCG+++S        
Sbjct: 244  LRLVGGDN---LCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKC 300

Query: 1190 FGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1236
            +G G G I LD+V CSG E +L QC++R W  H+C H+ED  VICSG
Sbjct: 301  YGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG 347



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 46/101 (45%), Positives = 55/101 (54%), Gaps = 1/101 (0%)

Query: 1135 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSG 1193
            V L    G C GRVE+ H   W TVC   W+++ A+VVCRQLGCGRAV           G
Sbjct: 138  VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYG 197

Query: 1194 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
              PI L  + CSG E+TL  C +  W  + CNH ED  V C
Sbjct: 198  RKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC 238



 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 42/105 (40%), Positives = 55/105 (52%), Gaps = 6/105 (5%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF---GSGSGPITLD 1200
            C GRVE+   G WGTVCDD W I++  V+CR+LGCG A        +         + + 
Sbjct: 33   CEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQ 92

Query: 1201 DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLS-TPAP 1244
             V C+GTE TL QC       ++C+H EDAG  C     S +P P
Sbjct: 93   SVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVP 135


>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
          Length = 756

 Score =  268 bits (685), Expect = 3e-71
 Identities = 194/544 (35%), Positives = 256/544 (47%), Gaps = 93/544 (17%)

Query: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
           LRLV  + + + GR+E+L++G WGTVCDD++   +A V CRQLG   A++   +A +GQG
Sbjct: 32  LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91

Query: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206
            GPI LD+VRC G ES L  C  NGW   +C H ED GVIC              +A  P
Sbjct: 92  EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151

Query: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266
           Q     E   VR+ P + +    S +            G VEV Y G W  VCD  W  N
Sbjct: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198

Query: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308
           ++ VVC  L  G+    P ++ + +    + + D                  V C G E 
Sbjct: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256

Query: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGSESSLA 362
           ++ +C     P  G L   C     A V C A P  RP   P T P    S A       
Sbjct: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310

Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
           +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   AR GQG 
Sbjct: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370

Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTL 482
           GPI L +VRC GYE  L  CP      + CQH  DA V C      + P+ G +++    
Sbjct: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQ---- 420

Query: 483 PTITLPASTVGSESSLALRL-VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 541
             + L    +  E  L +++ VNG  R            WG+VC ++W   +A V CRQL
Sbjct: 421 --VRLAGGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQL 466

Query: 542 GCGWAMLAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED---A 595
           G G+A+ A     F  G   +  +V+  VRCSG E  L  C  +G +  +C H      A
Sbjct: 467 GLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLA 524

Query: 596 GVIC 599
           GV C
Sbjct: 525 GVSC 528



 Score =  262 bits (669), Expect = 2e-69
 Identities = 188/536 (35%), Positives = 245/536 (45%), Gaps = 62/536 (11%)

Query: 488 PASTVGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 546
           P S   S  +  LRLV    + + GR+EVL++G WGTVCDD++   +A V CRQLG   A
Sbjct: 20  PPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAA 79

Query: 547 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSR- 605
           +    +A++GQG GPI LD+VRC G ES L  C  NGW   +C HSED GVIC   + R 
Sbjct: 80  LTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRG 139

Query: 606 ---STPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTND 662
               T      P            +           +G VEV Y+G W  VCD  W  N+
Sbjct: 140 YLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNN 199

Query: 663 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD------------------VRCSGHESY 704
           + VVC  L  G+    P ++ + +    + + D                  V C G E +
Sbjct: 200 SRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPH 257

Query: 705 LWSC-----PHNGWLSHNCGHSEDAGVICSAS-QSRPTPSPDTWPTSRASTAGSESTLAL 758
           + +C     P  G L   C     A V C A    RP   P T P  + S A       +
Sbjct: 258 MANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWAEEP---RV 311

Query: 759 RLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSG 818
           RL +G     GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   A+ GQG G
Sbjct: 312 RLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLG 371

Query: 819 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPA 878
           PI L +VRC G+E  L  CP      + C H  DA V C                 N+P 
Sbjct: 372 PIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC-----------------NVPN 414

Query: 879 LTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 938
           +   ++  LA   +        +VEV     WG+VC ++W   +A V CRQLG G+A+ A
Sbjct: 415 MGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHA 474

Query: 939 PGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED---AGVIC 988
                F  G   +  +V+  VRCSG E  L  C   G +  +C H      AGV C
Sbjct: 475 YKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528



 Score =  256 bits (655), Expect = 1e-67
 Identities = 192/542 (35%), Positives = 249/542 (45%), Gaps = 65/542 (11%)

Query: 348 PTSHASTAGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGC 406
           P S   + G+     LRLV    + + GR+EVL++G WGTVCDD++   +A V CRQLG 
Sbjct: 20  PPSRPQSLGTTK---LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGF 76

Query: 407 GWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAH 466
             A +   +A++GQG GPI LD+VRC G ES L  C  NGW   +C HSED GVIC    
Sbjct: 77  EAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICH--- 133

Query: 467 SWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR---CQGRVEVLYRGSWGT 523
               P       ++T+     P      E  L   L +        +G VEV Y G W  
Sbjct: 134 ----PRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQ 189

Query: 524 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDD----------------- 566
           VCD  W  N++ VVC  L  G+    P ++ + +    + + D                 
Sbjct: 190 VCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIH 247

Query: 567 -VRCSGNESYLWSC-----PHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHAST 620
            V C G E ++ +C     P  G L   C     A V C A      P+  T P    S 
Sbjct: 248 QVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK--TKPQRKGSW 305

Query: 621 AGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPG 680
           A       +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A  
Sbjct: 306 A---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALF 362

Query: 681 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPD 740
            AR GQG GPI L +VRC G+E  L  CP      + C H  DA V C+         P+
Sbjct: 363 GARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV--------PN 414

Query: 741 TWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLG 800
               ++   AG       R+   G     +VEV     WG+VC + W   +A V CRQLG
Sbjct: 415 MGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLG 467

Query: 801 CGWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLSHNCGHHEDAGV 855
            G+A+ A     F  G   +  +V+  VRCSG E  L  C  +G    SH  G    AGV
Sbjct: 468 LGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFL-AGV 526

Query: 856 IC 857
            C
Sbjct: 527 SC 528



 Score =  256 bits (654), Expect = 1e-67
 Identities = 187/545 (34%), Positives = 244/545 (44%), Gaps = 66/545 (12%)

Query: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
           PP     S  +  LRLV    +   GR+EVL++G WGTVCDD +   +A V CRQLG   
Sbjct: 19  PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78

Query: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
           A++   +A++GQG GPI LD+VRC G ES L  C  NGW   +C HSED GVIC   + R
Sbjct: 79  ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138

Query: 340 ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395
                T S    P            +           +G VEV Y G W  VCD  W  +
Sbjct: 139 GYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMN 198

Query: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGYES 437
           ++ VVC  L  G+ +  P ++ + +    + + D                  V C G E 
Sbjct: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256

Query: 438 YLWSC-----PHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTV 492
           ++ +C     P  G L   C     A V C A   +  P              T P    
Sbjct: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK-------------TKPQRKG 303

Query: 493 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 552
                  +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   
Sbjct: 304 SWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFG 363

Query: 553 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDT 612
           AR GQG GPI L +VRC G E  L  CP      + C H  DA V C+         P+ 
Sbjct: 364 ARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV--------PNM 415

Query: 613 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 672
              +    AG       R+   G   + +VEV     WG+VC ++W   +A V CRQLG 
Sbjct: 416 GFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGL 468

Query: 673 GWAMSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSED---AGV 726
           G+A+ A     F  G   +  +V+  VRCSG E  L  C  +G +  +C H      AGV
Sbjct: 469 GFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGV 526

Query: 727 ICSAS 731
            C  S
Sbjct: 527 SCMDS 531



 Score =  216 bits (551), Expect = 1e-55
 Identities = 147/404 (36%), Positives = 186/404 (46%), Gaps = 40/404 (9%)

Query: 614 PTSHASTAGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 672
           P S   + G+     LRLV    + + GR+EVL+QG WGTVCDD++   +A V CRQLG 
Sbjct: 20  PPSRPQSLGTTK---LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGF 76

Query: 673 GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQ 732
             A++   +A++GQG GPI LD+VRC G ES L  C  NGW   +C HSED GVIC   +
Sbjct: 77  EAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRR 136

Query: 733 SR----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWD 788
            R     T S    P  R         +            G VEV Y+G W  VCD  W 
Sbjct: 137 HRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWT 196

Query: 789 TNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGH 830
            N++ VVC  L  G+    P ++ + +    + + D                  V C G 
Sbjct: 197 MNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGT 254

Query: 831 ESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSES 885
           E ++ +C     P  G L   C     A V C A      P+         P        
Sbjct: 255 EPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK-------TKPQRKGSWAE 307

Query: 886 SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 945
              +RL +G     GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   AR G
Sbjct: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367

Query: 946 QGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           QG GPI L +VRC G E  L  CP      + C H  DA V C+
Sbjct: 368 QGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411



 Score =  110 bits (276), Expect = 9e-24
 Identities = 50/89 (56%), Positives = 63/89 (70%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
            GR+E+ H G WGTVCDD++ IQEA V CRQLG   A++   +A +G G GPI LD+V C 
Sbjct: 44   GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103

Query: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
            GTES+L QC + GW   +C+H ED GVIC
Sbjct: 104  GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 46/101 (45%), Positives = 52/101 (51%)

Query: 1135 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1194
            V L S   +  GRVE+     WGTVCD  W +  A VVCRQLG G A  AL  A  G G 
Sbjct: 311  VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370

Query: 1195 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            GPI L +V C G E TL  C       + C H  DA V C+
Sbjct: 371  GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)

Query: 1142 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1198
            GL   +VE+     WG+VC ++W + EA V CRQLG G A+ A    +F SG   +  + 
Sbjct: 432  GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491

Query: 1199 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1234
            +  V CSGTE  L QC+  G    +C+H   R  AGV C
Sbjct: 492  MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528



 Score = 39.3 bits (90), Expect = 0.032
 Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1191
            G VE+ + G W  VCD  WT+  + VVC  LG    V    + Y                
Sbjct: 177  GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236

Query: 1192 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1242
              +      +  V C GTE  +  C+      RG     C     A V C +G H   P
Sbjct: 237  SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295


>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
          Length = 753

 Score =  264 bits (675), Expect = 5e-70
 Identities = 192/549 (34%), Positives = 249/549 (45%), Gaps = 72/549 (13%)

Query: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDAN 398
           +PSP T P   A + G    LA     G  R   +GRVE+   G WGT+CDD +    A+
Sbjct: 26  SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAH 80

Query: 399 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDA 458
           ++CR+LG   AT    +A++G G+G I LD++ CSG E  +  C   GW + +C H EDA
Sbjct: 81  ILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDA 140

Query: 459 GVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR----CQGRVE 514
           GVIC          PG  D         L    V    +     V  G R     +G VE
Sbjct: 141 GVICKDQRL-----PGFSDSNVIEVEHHLQVEEVRIRPA-----VGWGRRPLPVTEGLVE 190

Query: 515 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF-----GQGSGPIVLDDVRC 569
           V     W  VCD  W  ++++VVC  LG  +      NA F      +      L  V C
Sbjct: 191 VRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVAC 248

Query: 570 SGNESYLWSCPHNGWLSHN---CGHSEDAGVICS-----AAQSRSTPRPDTWPTSHASTA 621
            G E++L  C    + +++   C     A V C      AA S    +  + P   A   
Sbjct: 249 VGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEAR-- 306

Query: 622 GSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 681
                  +RL  G    +GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A   
Sbjct: 307 -------VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSG 359

Query: 682 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT 741
           AR GQG G I L +VRCSG E  LW CPH    + +C HS+DAGV C+            
Sbjct: 360 ARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL----------- 408

Query: 742 WPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG----SWGTVCDDYWDTNDANVVCR 797
            P + A T        +RL  G  +  GRVEV   G     WG +C D W T +A V CR
Sbjct: 409 -PYTGAET-------RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACR 460

Query: 798 QLGCGWAMSAPGNAQFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDA 853
           QLG G+A        +        +V+  VRC+G E  L  C H+G        G    A
Sbjct: 461 QLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTA 520

Query: 854 GVICSAAQS 862
           GVICS   S
Sbjct: 521 GVICSETAS 529



 Score =  257 bits (657), Expect = 6e-68
 Identities = 182/553 (32%), Positives = 249/553 (45%), Gaps = 64/553 (11%)

Query: 460 VICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR-CQGRVEVLYR 518
           ++CS+     +PS G             P    GS+  L  RL     +  +GRVE+   
Sbjct: 18  LLCSSCLGSPSPSTG-------------PEKKAGSQG-LRFRLAGFPRKPYEGRVEIQRA 63

Query: 519 GSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWS 578
           G WGT+CDD +    A+++CR+LG   A     +A++G G+G I LD++ CSG E  +  
Sbjct: 64  GEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTE 123

Query: 579 CPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR- 637
           C   GW + +C H EDAGVIC   +       +     H         + +R   G  R 
Sbjct: 124 CASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRR 180

Query: 638 ----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF-----GQGS 688
                +G VEV     W  VCD  W  ++++VVC  LG  +      NA F      +  
Sbjct: 181 PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQ 238

Query: 689 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRAS 748
               L  V C G E++L  C    + +++       G    +    P  +  +    +  
Sbjct: 239 HSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQ 298

Query: 749 TAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP 808
           +   +    +RL  G     GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A 
Sbjct: 299 SK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREAL 357

Query: 809 GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRP 868
             A+ GQG G I L +VRCSG E  LW CPH    + +C H +DAGV C           
Sbjct: 358 SGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC----------- 406

Query: 869 DTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDSWDTNDAN 924
                 NLP    G+E+ +  RL  G  +  GRVEV   G     WG +C D W T +A 
Sbjct: 407 ------NLPY--TGAETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAM 456

Query: 925 VVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGWLTH----NC 978
           V CRQLG G+A        +        +V+  VRC+G E  L  C H G  TH      
Sbjct: 457 VACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRT 514

Query: 979 GHHEDAGVICSAT 991
           G    AGVICS T
Sbjct: 515 GTRFTAGVICSET 527



 Score =  251 bits (642), Expect = 3e-66
 Identities = 185/565 (32%), Positives = 253/565 (44%), Gaps = 59/565 (10%)

Query: 59  TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117
           +V + SP  L   L  +   GS  PS ST      +    GL  RL     +  +GRVEI
Sbjct: 5   SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60

Query: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177
              G WGT+CDD +    A+++CR+LG   A     +A +G G+G I LD++ CSG E  
Sbjct: 61  QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120

Query: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237
           +  C   GW + +C H EDAGVIC   +       +S  + +   +  E     + +R  
Sbjct: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174

Query: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289
            G  R       G VEV     W  VCD  W  ++++VVC  LG  +      NA F   
Sbjct: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRL 232

Query: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347
              +      L  V C G E++L  C    +  ++       G    +    P  +  + 
Sbjct: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292

Query: 348 PTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
                 +   +    +RL  G    +GRVEVL   +WGTVCD  WD   A+VVCR+LG G
Sbjct: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351

Query: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
            A  A   AR GQG G I L +VRCSG E  LW CPH    + +C HS+DAGV C+  ++
Sbjct: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411

Query: 468 WSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRG----SWGT 523
                                    G+E+   +RL  G  + +GRVEV   G     WG 
Sbjct: 412 -------------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGL 444

Query: 524 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPH 581
           +C D W T +A V CRQLG G+A        +        +V+  VRC+G E  L  C H
Sbjct: 445 ICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAH 504

Query: 582 NGW--LSHNCGHSEDAGVICSAAQS 604
           +G        G    AGVICS   S
Sbjct: 505 HGTHITCKRTGTRFTAGVICSETAS 529



 Score =  208 bits (530), Expect = 3e-53
 Identities = 142/415 (34%), Positives = 190/415 (45%), Gaps = 31/415 (7%)

Query: 597 VICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYQGSWGTVC 654
           ++CS+     +P P T P   A + G    LA     G  R   +GRVE+   G WGT+C
Sbjct: 18  LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70

Query: 655 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 714
           DD +    A+++CR+LG   A     +A++G G+G I LD++ CSG E  +  C   GW 
Sbjct: 71  DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130

Query: 715 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR----CRGR 770
           + +C H EDAGVIC     R     D+           E       V  G R      G 
Sbjct: 131 NSDCTHDEDAGVICK--DQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGL 188

Query: 771 VEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDDV 825
           VEV     W  VCD  W  ++++VVC  LG  +      NA F      +      L  V
Sbjct: 189 VEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGV 246

Query: 826 RCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVG 882
            C G E++L  C    + +++   C     A V C      +          + P     
Sbjct: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP----- 301

Query: 883 SESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 942
            +    +RL  G     GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A   A
Sbjct: 302 -QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA 360

Query: 943 RFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 997
           R GQG G I L +VRCSG E  LW CPHK     +C H +DAGV C+     + T
Sbjct: 361 RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415



 Score =  107 bits (266), Expect = 1e-22
 Identities = 46/94 (48%), Positives = 63/94 (67%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
            GRVEI   G WGT+CDD +T+Q A ++CR+LG   A     +A +G G+G I LD++ CS
Sbjct: 56   GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1239
            GTE ++ +C +RGW + +C H EDAGVIC    L
Sbjct: 116  GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 44/90 (48%), Positives = 57/90 (63%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
            GRVE+    TWGTVCD  W +  A VVCR+LG G A  AL  A  G G G I L +V CS
Sbjct: 318  GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377

Query: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            G E +LW+C ++   + +C+H +DAGV C+
Sbjct: 378  GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 1146 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1199
            GRVE+  GG     WG +C D W   EA V CRQLG G A   L    Y+ SG+   + +
Sbjct: 428  GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487

Query: 1200 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1235
              V C+GTE +L QC + G          R  AGVICS
Sbjct: 488  SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525



 Score = 34.7 bits (78), Expect = 0.79
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1202
            G VE+     W  VCD  W+   + VVC  LG     R  +A              L  V
Sbjct: 187  GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246

Query: 1203 ECSGTESTLWQC 1214
             C GTE+ L  C
Sbjct: 247  ACVGTEAHLSLC 258


>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
          Length = 774

 Score =  257 bits (656), Expect = 8e-68
 Identities = 190/581 (32%), Positives = 263/581 (45%), Gaps = 84/581 (14%)

Query: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241
           C H      + +   P S  + +SWP        P P         + + + LRL     
Sbjct: 6   CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65

Query: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
           +   GRVEV Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD+
Sbjct: 66  KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125

Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360
           + C+G+E+ L +C  NGW   +C H+ED GV+CS  +       ++      +       
Sbjct: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185

Query: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415
           + +R +    R      +G VEV    +W  +CD  W   ++ VVC   G       PG 
Sbjct: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239

Query: 416 ARFG------------QGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN------CQHSED 457
             +             Q   P  +D   C+G E+++ SC     +S +      C++   
Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296

Query: 458 AGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLY 517
           A V C     +S   P  R R    P   L            +RL  G    +GRVEVL 
Sbjct: 297 AVVSCVPGQVFSPDGPS-RFRKAYKPEQPL------------VRLRGGAYIGEGRVEVLK 343

Query: 518 RGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLW 577
            G WGTVCDD WD   A+VVCR+LG G A  A   +R GQG GPI L++++C+GNE  + 
Sbjct: 344 NGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSII 403

Query: 578 SCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR 637
            C  N   S  C H EDAGV C                   +T        LRL  G + 
Sbjct: 404 DCKFNA-ESQGCNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNP 443

Query: 638 CQGRVEVLYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGP 690
            +GRVEVL + +    WG VC  +W   +A VVCRQLG G+A +A     +  G   S  
Sbjct: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503

Query: 691 IVLDDVRCSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 729
           +V+  V+CSG E  L  C H+G        G    AGV CS
Sbjct: 504 VVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544



 Score =  255 bits (652), Expect = 2e-67
 Identities = 181/514 (35%), Positives = 244/514 (47%), Gaps = 68/514 (13%)

Query: 510 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRC 569
           +GRVEV Y G WGTVCDD +  + A+VVCR+LG   A     ++ +G+G GPI LD++ C
Sbjct: 69  EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128

Query: 570 SGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLAL 629
           +GNE+ L +C  NGW   +C H+ED GV+CS  +       ++      +       + +
Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188

Query: 630 RLVNGGDR-----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN--- 681
           R +    R      +G VEV    +W  +CD  W   ++ VVC   G       PG    
Sbjct: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242

Query: 682 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHSEDAGV 726
                    +R  Q   P  +D   C+G E+++ SC     +S +      C +   A V
Sbjct: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299

Query: 727 ICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 786
            C   Q     SPD    SR   A       +RL  G     GRVEVL  G WGTVCDD 
Sbjct: 300 SCVPGQ---VFSPD--GPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354

Query: 787 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 846
           WD   A+VVCR+LG G A  A   ++ GQG GPI L++++C+G+E  +  C  N   S  
Sbjct: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413

Query: 847 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 906
           C H EDAGV C                 N PA+ +  +    LRL  G +   GRVEVL 
Sbjct: 414 CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452

Query: 907 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 959
             +    WG VC  +W   +A VVCRQLG G+A +A     +  G   S  +V+  V+CS
Sbjct: 453 ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512

Query: 960 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 991
           G E  L  C H G        G    AGV CS T
Sbjct: 513 GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546



 Score =  248 bits (633), Expect = 3e-65
 Identities = 181/521 (34%), Positives = 246/521 (47%), Gaps = 77/521 (14%)

Query: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171
           +GRVE+ Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD++ C
Sbjct: 69  EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128

Query: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231
           +G+E+ L +C  NGW   +C H ED GV+CS  +        S    I+           
Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNS---LINQIENLNIQVED 185

Query: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           + +R +    R R     G VEV    +W  +CD +W   ++ VVC   G       PG 
Sbjct: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239

Query: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328
             +             Q   P  +D   C+G E+++ SC     ++ +      C +   
Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296

Query: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
           A V C   Q     SPD  P+        E  L +RL  G    +GRVEVL  G WGTVC
Sbjct: 297 AVVSCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351

Query: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
           DD WD   A+VVCR+LG G A  A   +R GQG GPI L++++C+G E  +  C  N   
Sbjct: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410

Query: 449 SHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR 508
           S  C H EDAGV C      +TP+ G + +                     LRL  G + 
Sbjct: 411 SQGCNHEEDAGVRC------NTPAMGLQKK---------------------LRLNGGRNP 443

Query: 509 CQGRVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGP 561
            +GRVEVL   +    WG VC  +W   +A VVCRQLG G+A  A     +  G   S  
Sbjct: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503

Query: 562 IVLDDVRCSGNESYLWSCPHNG--WLSHNCGHSEDAGVICS 600
           +V+  V+CSG E  L  C H+G        G    AGV CS
Sbjct: 504 VVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544



 Score =  145 bits (366), Expect = 3e-34
 Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           +RL  G    +GRVE+L  G WGTVCDD WD   A+VVCR+LG G A  A   +  GQG 
Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
           GPI L++++C+G+E  +  C  N   S  C H EDAGV C+                   
Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425

Query: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277
             P  G +    LRL  G +   GRVEVL   +    WG VC   W   +A VVCRQLG 
Sbjct: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482

Query: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332
           G+A +A     +  G   S  +V+  V+CSG E  L  C H+G        G    AGV 
Sbjct: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542

Query: 333 CS 334
           CS
Sbjct: 543 CS 544



 Score =  107 bits (266), Expect = 1e-22
 Identities = 46/94 (48%), Positives = 62/94 (65%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
            GRVE+Y+ G WGTVCDD ++I  A VVCR+LG   A S   ++ +G G GPI LD++ C+
Sbjct: 70   GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1239
            G E+TL  C + GW   +C H ED GV+CS   +
Sbjct: 130  GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163



 Score =  103 bits (256), Expect = 2e-21
 Identities = 47/94 (50%), Positives = 63/94 (67%)

Query: 900 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 959
           GRVEV Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD++ C+
Sbjct: 70  GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 960 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 993
           GNE+ L +C   GW   +C H ED GV+CS  +I
Sbjct: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163



 Score = 98.2 bits (243), Expect = 6e-20
 Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%)

Query: 1134 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1193
            LV L     +  GRVE+   G WGTVCDD W +  A VVCR+LG G A  A+  +  G G
Sbjct: 325  LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384

Query: 1194 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
             GPI L++++C+G E ++  C+     S  CNH EDAGV C+
Sbjct: 385  IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 1127 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182
            P+    + + LN       GRVE+    +G   WG VC  +W I EA VVCRQLG G A 
Sbjct: 427  PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486

Query: 1183 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1218
            +A    ++  G   S  + +  V+CSGTE +L  CR+ G
Sbjct: 487  NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1199
            G VE+  G TW  +CD  WT + + VVC   G    R  +      F S       P ++
Sbjct: 204  GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263

Query: 1200 DDVECSGTESTLWQCR 1215
            D   C+GTE+ +  C+
Sbjct: 264  D---CTGTEAHISSCK 276


>gi|194018748 CD6 molecule [Homo sapiens]
          Length = 668

 Score =  241 bits (615), Expect = 4e-63
 Identities = 165/455 (36%), Positives = 207/455 (45%), Gaps = 84/455 (18%)

Query: 330 GVICSAPQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 386
           G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 387 VCDDSWDTSDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 431
            C   WD+  A  VCR LGCG A +               A GN      +       + 
Sbjct: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128

Query: 432 CSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPAST 491
           CSG E  L        + H C+                  S G R R             
Sbjct: 129 CSGAEWRLCEV-----VEHACR------------------SDGRRAR------------- 152

Query: 492 VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPG 551
           V    + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A  
Sbjct: 153 VTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212

Query: 552 NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPD 611
              F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS       
Sbjct: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS------- 264

Query: 612 TWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLG 671
            W                RL  G DRC+G+VEV ++G W TVCD  W  ++A V+C+ LG
Sbjct: 265 -W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLG 307

Query: 672 CGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 731
           CG A+  P        SG +      C+G E  L +C      S+ C  S  A V+CSAS
Sbjct: 308 CGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSAS 363

Query: 732 QSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR 766
           +S    S    P S   T   ES++ +++ N   R
Sbjct: 364 RSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397



 Score =  235 bits (600), Expect = 2e-61
 Identities = 159/439 (36%), Positives = 195/439 (44%), Gaps = 87/439 (19%)

Query: 86  STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145
           S+ ES + E  +  L +RL NG   C G VE+    SW   C   WD+  A  VCR LGC
Sbjct: 30  SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88

Query: 146 GWAMSAP---------------GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190
           G A +A                GN      +       + CSG E  L        + H 
Sbjct: 89  GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143

Query: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249
           C   G  A V C+                            + ALRLV+GG  C GRVE+
Sbjct: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176

Query: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309
           L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG E+Y
Sbjct: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236

Query: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGG 369
           LW CP      H CGH EDAG +CS  QS        W                RL  G 
Sbjct: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271

Query: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429
           DRC+G+VEV +RG W TVCD  W  S+A V+C+ LGCG A   P        SG +    
Sbjct: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329

Query: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPA 489
             C+G E  L +C      S+ C  S  A V+CSA+ S    S          P +    
Sbjct: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS---------TPEVPASV 378

Query: 490 STVGSESSLALRLVNGGDR 508
            TV  ESS+ +++ N   R
Sbjct: 379 QTVTIESSVTVKIENKESR 397



 Score =  235 bits (599), Expect = 3e-61
 Identities = 161/447 (36%), Positives = 207/447 (46%), Gaps = 66/447 (14%)

Query: 459 GVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYR 518
           G++ +A     +P+P      D L T +  +        L +RL NG   C G VEV   
Sbjct: 9   GLLTAALSGHPSPAP-----PDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLE 63

Query: 519 GSWGTVCDDSWDTNDANVVCRQLGCGWA----MLAPGNARFGQGSGPIVLDDVRCSGNES 574
            SW   C   WD+  A  VCR LGCG A     LAP             L     +GN S
Sbjct: 64  ASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPE---------LPPPPAAGNTS 114

Query: 575 YLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAG--SESSLALRLV 632
                     ++ N   +    ++CS A+ R     +    S    A      + ALRLV
Sbjct: 115 ----------VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLV 164

Query: 633 NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 692
           +GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI 
Sbjct: 165 DGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIH 224

Query: 693 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGS 752
            D V CSG E+YLW CP      H CGH EDAG +CS  QS        W          
Sbjct: 225 RDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W---------- 265

Query: 753 ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQ 812
                 RL  G DRC G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  P    
Sbjct: 266 ------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLP 319

Query: 813 FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWL 872
               SG +      C+G E  L +C      S+ C     A V+CSA++S          
Sbjct: 320 HSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLS 370

Query: 873 TTNLPA--LTVGSESSLALRLVNGGDR 897
           T  +PA   TV  ESS+ +++ N   R
Sbjct: 371 TPEVPASVQTVTIESSVTVKIENKESR 397



 Score =  229 bits (585), Expect = 1e-59
 Identities = 152/404 (37%), Positives = 197/404 (48%), Gaps = 55/404 (13%)

Query: 596 GVICSAAQSRSTPRP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYQGSWGT 652
           G++ +A     +P P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 653 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPHN 711
            C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 69  ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114

Query: 712 GWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS---RASTAGSESTLALRLVNGGDRCR 768
             ++ N   +    ++CS ++ R     +    S   RA    +E+  ALRLV+GG  C 
Sbjct: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENR-ALRLVDGGGACA 171

Query: 769 GRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCS 828
           GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CS
Sbjct: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231

Query: 829 GHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLA 888
           G E+YLW CP      H CGH EDAG +CS  QS        W                 
Sbjct: 232 GAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------- 265

Query: 889 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 948
            RL  G DRC G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+  P        S
Sbjct: 266 -RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-S 323

Query: 949 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 992
           G +      C+G E  L +C  +   ++ C     A V+CSA++
Sbjct: 324 GRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364



 Score =  180 bits (456), Expect = 1e-44
 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%)

Query: 725  GVICSASQSRPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 781
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 782  VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 840
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114

Query: 841  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 900
              ++ N        ++CS A+ +     +    ++     V    + ALRLV+GG  C G
Sbjct: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172

Query: 901  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232

Query: 961  NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 998
             E+YLW CP      H CGH EDAG +CS  Q                       N+   
Sbjct: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291

Query: 999  DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1043
              W+P+       S  CG  +    G   S S   YY  N      + C W
Sbjct: 292  SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342



 Score =  117 bits (292), Expect = 1e-25
 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 1133 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1192
            R + L    G CAGRVE+   G WG+VCDD+W +++A VVCRQLGCG AV AL   +F  
Sbjct: 159  RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218

Query: 1193 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            G GPI  D V CSG E+ LW C       H C H+EDAG +CS
Sbjct: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%)

Query: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1195
            C G+VE++  G W TVCD  W   EA+V+C+ LGCG AV        S  G  Y+     
Sbjct: 274  CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328

Query: 1196 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1242
                    C+G E TL  C  R   S+ C+    A V+CS     ++LSTP
Sbjct: 329  -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184
            +RL N +SS   C+G VE+    +W   C   W  + AE VCR LGCG A +A
Sbjct: 45   VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score =  151 bits (381), Expect = 6e-36
 Identities = 114/393 (29%), Positives = 176/393 (44%), Gaps = 54/393 (13%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CG  L  ++G  SSP +P  YP+   C+W + V  G +I L F+ + L     C +DY+E
Sbjct: 349  CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408

Query: 1075 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF------P 1127
            + DG    S LLG+ C D   ++ TS+ +RM I FRS  ++   GF A Y +        
Sbjct: 409  VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIRK 468

Query: 1128 SDATLRLVNLNSSYGL---CAGRV---EIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG-- 1179
            ++  ++  N    Y     C  ++   E YH G          T Q  E+  R   C   
Sbjct: 469  NEGQIQSPNYPDDYRPMKECVWKITVSESYHVGL---------TFQSFEIE-RHDNCAYD 518

Query: 1180 ----RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHNCNHRED 1229
                R  ++  +   G   G    +D+    T +TLW         N+  F+ N    ED
Sbjct: 519  YLEVRDGTSENSPLIGRFCGYDKPEDIR--STSNTLWMKFVSDGTVNKAGFAANFFKEED 576

Query: 1230 AGVI-----CSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 1275
                     C    L+T         P   L   R + + +CGG L++ +G  ++P +P 
Sbjct: 577  ECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPK 636

Query: 1276 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDG- 1332
             YP N  CVW +     YR++V F   +LEG   C YDY+E++ G    S L  + C   
Sbjct: 637  EYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAE 696

Query: 1333 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYS 1365
                 TS  N M I F SD++++++GF+A ++S
Sbjct: 697  VPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS 729



 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 1/114 (0%)

Query: 1013 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
            + C   +   SG  +SP++P  YP+  +C WEI    G+RI L FS  ++E H  C++D+
Sbjct: 772  AECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDH 831

Query: 1073 VEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1125
            +E+FDG    S +LG++C N       ++ N+M + F SD S Q  GF A +++
Sbjct: 832  LEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHST 885



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 38/110 (34%), Positives = 64/110 (58%), Gaps = 3/110 (2%)

Query: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1314
            C   +  PSG  +SP +P  YP+  +C W+I     +R+ + F + ++E    C YD++E
Sbjct: 774  CEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 833

Query: 1315 VFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1363
            VFDG    SP++ R+C +       ++ N M +RF+SD S+ R+GF+A +
Sbjct: 834  VFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATH 883



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 41/111 (36%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 1256 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIF--RDVQLEGGCNYDYI 1313
            +CG  L + +G+ SSP +P  YP+   C+W + V    ++ + F   D+     C YDYI
Sbjct: 348  ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407

Query: 1314 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1363
            EV DG +R SPL+ R C D      TS+ + M I F S  +   +GF A Y
Sbjct: 408  EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 7/123 (5%)

Query: 1009 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1064
            A  S+ CGG L   S      S+  +    YP    C W +    G R+ L F   ++E 
Sbjct: 881  ATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEE 940

Query: 1065 HHNCSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1122
              +C +DYVE+FDG  ++++ LG+ C      +I+ S  + + IHF +D +    GF   
Sbjct: 941  EADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIY-SIGDSVLIHFHTDDTINKKGFHIR 999

Query: 1123 YNS 1125
            Y S
Sbjct: 1000 YKS 1002



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 7/124 (5%)

Query: 1257 CGGFL---SQPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 1310
            CGG L   S+P   +S + F   NYP    C W +  +   R+ + F+  +V+ E  C Y
Sbjct: 887  CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946

Query: 1311 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 1369
            DY+E+FDG   ++  + R C  G      S  + + I F +D +I ++GF   Y S    
Sbjct: 947  DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRYP 1006

Query: 1370 DSTN 1373
            D+T+
Sbjct: 1007 DTTH 1010


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score =  144 bits (364), Expect = 5e-34
 Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CG  L   +G FS+P +P  YP+ + CVW I V  G +I L F+++ L     C +DYVE
Sbjct: 351  CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410

Query: 1075 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1128
            + DG    + LLG+ C D   +   S+ +R+ + FRS  +    GF A Y +        
Sbjct: 411  VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470

Query: 1129 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1179
            DA  ++  N    Y     C  R+ +  G   G       T Q  E+  R   C      
Sbjct: 471  DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523

Query: 1180 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1223
             R      +A  G   G    +DV+ S     LW         N+  F+ N         
Sbjct: 524  VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581

Query: 1224 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 1277
                  C HR     + S      P   L   +   + +CGGF+++ +G  +SP +P  Y
Sbjct: 582  WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640

Query: 1278 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 1335
            P N  CVW +     YR+++ F   +LEG   C YD++EV  G    + L  R C     
Sbjct: 641  PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700

Query: 1336 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 1365
               TS SN M + F SD+++++RGFRA ++S
Sbjct: 701  EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CGGF+   +GT +SP +P  YP N  CVW++   + YRI+L F   +LE +  C +D+VE
Sbjct: 620  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679

Query: 1075 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1133
            +  G    + L G+ C ++T ++ TS  N M + F+SD +    GF A + S   +    
Sbjct: 680  VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737

Query: 1134 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1185
                    G C     +   G++   C + + + E    C++ GC   +S++
Sbjct: 738  -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%)

Query: 1013 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
            + CGG +   +G   SP+YP  Y  + +CVW I V+ G+ + L F   ++E H +C++DY
Sbjct: 462  ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521

Query: 1073 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1131
            +E+ DG    S L+G  C  +  +   SS NR+ + F SD S    GF A +     + +
Sbjct: 522  LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581

Query: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1191
                     +G C  R  +   G++   CD  + +   + +C ++ CG  ++ L      
Sbjct: 582  W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633

Query: 1192 SG 1193
             G
Sbjct: 634  PG 635



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%)

Query: 1203 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 1261
            EC  T  S L +CRN  W   N +  ++AG                         C   +
Sbjct: 746  ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780

Query: 1262 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 1319
            S   G  +SP +P  YP+  +C W+I     +RV + F + ++E    C YD++E++DGP
Sbjct: 781  SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840

Query: 1320 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 1361
               +P++ R C   +   T +S + M +RF SD S+ R+GF+A
Sbjct: 841  DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%)

Query: 1013 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
            + C   +    GT +SP++P  YP+  +C W I   +G+R+ L F+  ++E H  C++D+
Sbjct: 774  AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833

Query: 1073 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1125
            +E++DG  + + +LG+ C   +   T +S + M + F SD S Q  GF A +++
Sbjct: 834  LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%)

Query: 1257 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 1310
            CGG L    Q    +S + F   NYP+ A+C W I  ++ Y V + FR  +V+ E  C Y
Sbjct: 889  CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948

Query: 1311 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 1369
            DY+E +DG   S+P + R C  G      S+ + + IRF +D +I ++GF A Y S+   
Sbjct: 949  DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008

Query: 1370 DSTNL 1374
            D+ ++
Sbjct: 1009 DALHM 1013



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)

Query: 1256 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1313
            +CG  L   +G+FS+P +P  YP+ + CVW I V    ++ + F  + L     C YDY+
Sbjct: 350  ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409

Query: 1314 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 1370
            EV DG +R +PL+ R C D       S+ + + + F S  +I  +GF A Y ++   D
Sbjct: 410  EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)

Query: 1012 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1067
            S+ CGG L     T    S+  +    YP+ A+C W I    GY + L F   ++E   +
Sbjct: 886  STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945

Query: 1068 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1125
            C +DY+E +DG  +S+  LG+ C      +I+ S+ + + I FR+D +    GF A Y S
Sbjct: 946  CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004


>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
            sapiens]
          Length = 730

 Score =  138 bits (348), Expect = 4e-32
 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CG  L  ++G FSSP YP  Y  +  CVW I V  G +I L F++L L     C +DYVE
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 1075 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1131
            + DG    + L G+ C     +   S+ +R+ + FRS  ++   GF A Y +        
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441

Query: 1132 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184
                ++  N    Y    +C  R+++  G   G     S+ I+  +         R   +
Sbjct: 442  DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500

Query: 1185 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1231
              +   G   G    DD++   T S LW         N+  F+ N       C+     G
Sbjct: 501  ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558

Query: 1232 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 1282
              C    L+T         P   L   +   + +CGGFL++ +G  +SP +P  YP N  
Sbjct: 559  --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616

Query: 1283 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 1339
            C+W +     YR+++ F   + EG   C YD++EV  G    S L  + C   +    TS
Sbjct: 617  CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676

Query: 1340 SSNFMSIRFISDHSITRRGFRAEYYS 1365
              N M + F SD++++++GF+A ++S
Sbjct: 677  QYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 43/117 (36%), Positives = 65/117 (55%), Gaps = 1/117 (0%)

Query: 1010 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1069
            R  + CGGFL   +G+ +SP +P  YP N  C+W++   + YRI+L F   + E +  C 
Sbjct: 586  RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645

Query: 1070 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1125
            +D+VE+  G    S L GK C   + ++ TS YN M + F+SD +    GF A + S
Sbjct: 646  YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%)

Query: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1314
            CGG + +  G   SP YP +Y  +  C+W I+V   + V + F+  ++E    C YDY+E
Sbjct: 435  CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494

Query: 1315 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 1367
            V DG   SS LI R C   +     S+S+ + ++F+SD SI + GF   ++      S P
Sbjct: 495  VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554

Query: 1368 SNDSTNLLCL 1377
            +       CL
Sbjct: 555  NRGGCEQRCL 564



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 1256 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1313
            +CG  L   +G+FSSP YP  Y  +  CVW I V    ++ + F  + L     C YDY+
Sbjct: 321  ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 1314 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1363
            EV DG +R +PL  R C         S+ + + + F S  +   +GF A Y
Sbjct: 381  EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
            sapiens]
          Length = 823

 Score =  138 bits (348), Expect = 4e-32
 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CG  L  ++G FSSP YP  Y  +  CVW I V  G +I L F++L L     C +DYVE
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 1075 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1131
            + DG    + L G+ C     +   S+ +R+ + FRS  ++   GF A Y +        
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441

Query: 1132 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184
                ++  N    Y    +C  R+++  G   G     S+ I+  +         R   +
Sbjct: 442  DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500

Query: 1185 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1231
              +   G   G    DD++   T S LW         N+  F+ N       C+     G
Sbjct: 501  ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558

Query: 1232 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 1282
              C    L+T         P   L   +   + +CGGFL++ +G  +SP +P  YP N  
Sbjct: 559  --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616

Query: 1283 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 1339
            C+W +     YR+++ F   + EG   C YD++EV  G    S L  + C   +    TS
Sbjct: 617  CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676

Query: 1340 SSNFMSIRFISDHSITRRGFRAEYYS 1365
              N M + F SD++++++GF+A ++S
Sbjct: 677  QYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 43/117 (36%), Positives = 65/117 (55%), Gaps = 1/117 (0%)

Query: 1010 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1069
            R  + CGGFL   +G+ +SP +P  YP N  C+W++   + YRI+L F   + E +  C 
Sbjct: 586  RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645

Query: 1070 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1125
            +D+VE+  G    S L GK C   + ++ TS YN M + F+SD +    GF A + S
Sbjct: 646  YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%)

Query: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1314
            CGG + +  G   SP YP +Y  +  C+W I+V   + V + F+  ++E    C YDY+E
Sbjct: 435  CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494

Query: 1315 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 1367
            V DG   SS LI R C   +     S+S+ + ++F+SD SI + GF   ++      S P
Sbjct: 495  VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554

Query: 1368 SNDSTNLLCL 1377
            +       CL
Sbjct: 555  NRGGCEQRCL 564



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 1256 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1313
            +CG  L   +G+FSSP YP  Y  +  CVW I V    ++ + F  + L     C YDY+
Sbjct: 321  ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 1314 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1363
            EV DG +R +PL  R C         S+ + + + F S  +   +GF A Y
Sbjct: 381  EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
            sapiens]
          Length = 986

 Score =  138 bits (348), Expect = 4e-32
 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CG  L  ++G FSSP YP  Y  +  CVW I V  G +I L F++L L     C +DYVE
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 1075 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1131
            + DG    + L G+ C     +   S+ +R+ + FRS  ++   GF A Y +        
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441

Query: 1132 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184
                ++  N    Y    +C  R+++  G   G     S+ I+  +         R   +
Sbjct: 442  DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500

Query: 1185 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1231
              +   G   G    DD++   T S LW         N+  F+ N       C+     G
Sbjct: 501  ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558

Query: 1232 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 1282
              C    L+T         P   L   +   + +CGGFL++ +G  +SP +P  YP N  
Sbjct: 559  --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616

Query: 1283 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 1339
            C+W +     YR+++ F   + EG   C YD++EV  G    S L  + C   +    TS
Sbjct: 617  CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676

Query: 1340 SSNFMSIRFISDHSITRRGFRAEYYS 1365
              N M + F SD++++++GF+A ++S
Sbjct: 677  QYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score =  104 bits (260), Expect = 6e-22
 Identities = 87/356 (24%), Positives = 144/356 (40%), Gaps = 87/356 (24%)

Query: 1010 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1069
            R  + CGGFL   +G+ +SP +P  YP N  C+W++   + YRI+L F   + E +  C 
Sbjct: 586  RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645

Query: 1070 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPS 1128
            +D+VE+  G    S L GK C   + ++ TS YN M + F+SD +    GF A + S   
Sbjct: 646  YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKD 705

Query: 1129 DATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA 1188
            + +        + G     V  +  G++   C   + + + +  C++ GC   V+     
Sbjct: 706  ECS------KDNGGCQQDCVNTF--GSYECQCRSGFVLHDNKHDCKEAGCDHKVT----- 752

Query: 1189 YFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNI 1248
               S SG IT                      S N   +  +   C+    STP   + +
Sbjct: 753  ---STSGTIT----------------------SPNWPDKYPSKKECTWAISSTPGHRVKL 787

Query: 1249 TRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGC 1308
            T    D       SQP                 +C +D                      
Sbjct: 788  TFMEMDIE-----SQP-----------------ECAYD---------------------- 803

Query: 1309 NYDYIEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1363
               ++EVFDG    +P++ R C   +     ++ + M +RF SD+S+ R+GF+A +
Sbjct: 804  ---HLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%)

Query: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1314
            CGG + +  G   SP YP +Y  +  C+W I+V   + V + F+  ++E    C YDY+E
Sbjct: 435  CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494

Query: 1315 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 1367
            V DG   SS LI R C   +     S+S+ + ++F+SD SI + GF   ++      S P
Sbjct: 495  VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554

Query: 1368 SNDSTNLLCL 1377
            +       CL
Sbjct: 555  NRGGCEQRCL 564



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 52/199 (26%), Positives = 89/199 (44%), Gaps = 15/199 (7%)

Query: 1013 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
            + C   +   SGT +SP++P  YP+  +C W I    G+R+ L F  + +E+   C++D+
Sbjct: 745  AGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDH 804

Query: 1073 VEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1131
            +E+FDG    + +LG+ C   + +   ++ +RM + F SD S Q  GF A + +      
Sbjct: 805  LEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQV 864

Query: 1132 LRLVNLNSSYGLCAGRVEIYHGGT---WGTVCDDSWTIQ---EAEVVCRQLGCGRAVSAL 1185
               V     Y         Y GG    W  V ++ + ++   +   V  +  CG     L
Sbjct: 865  RADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMEL 924

Query: 1186 GNAYFGS--------GSGP 1196
             + Y  +        GSGP
Sbjct: 925  FDGYDSTAPRLGRYCGSGP 943



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 3/103 (2%)

Query: 1272 FYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSSPLIARV 1329
            F   NYP    C W I  +  Y V ++F+  +V+ E  C YDY+E+FDG   ++P + R 
Sbjct: 879  FGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRY 938

Query: 1330 C-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDS 1371
            C  G      S+ + + ++F SD +IT++GF   Y S+   D+
Sbjct: 939  CGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDT 981



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 1256 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1313
            +CG  L   +G+FSSP YP  Y  +  CVW I V    ++ + F  + L     C YDY+
Sbjct: 321  ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 1314 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1363
            EV DG +R +PL  R C         S+ + + + F S  +   +GF A Y
Sbjct: 381  EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
          Length = 449

 Score =  136 bits (342), Expect = 2e-31
 Identities = 115/377 (30%), Positives = 156/377 (41%), Gaps = 40/377 (10%)

Query: 1003 PTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKL 1062
            P     A     CGG L   SG FSSP++P  YP N +C W I V  G  + L F    L
Sbjct: 18   PGLQAQAMEGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDL 77

Query: 1063 EAHHNCSFDYVEIFDG-SLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFL 1120
            E H  CSFD++EI++G S +   LLG+ C       FTSS++ M++ F SD    + GF 
Sbjct: 78   EYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFS 137

Query: 1121 AWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGR 1180
            A Y        L         GL        +   +    +  W I+ A         G 
Sbjct: 138  AGYQKDVCGGVLT--------GLSGVLTSPEYPNNYPNSMECHWVIRAA---------GP 180

Query: 1181 A-VSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1239
            A V  +   +   G+   T D V   G          RG   H C       ++  G+ L
Sbjct: 181  AHVKLVFVDFQVEGNEECTYDYVAVLGGPGP-----TRG--HHYCGSTRPPTLVSLGHEL 233

Query: 1240 ST--PAPFLNITRPNTDY----SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNY 1293
                 + F    R    Y     C        G+FSSP YP +YPNN +C W I +   Y
Sbjct: 234  QVVFKSDFNIGGRGFKAYYFSGECQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGY 293

Query: 1294 RVTVIFRDVQLE------GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSI 1346
            +V V F D+ LE        C++D++  FDG    +PL+   C        TSS N + +
Sbjct: 294  QVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLL 353

Query: 1347 RFISDHSITRRGFRAEY 1363
               +D S TRRGF   Y
Sbjct: 354  LLHTDRSTTRRGFSVAY 370



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 5/112 (4%)

Query: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIE 1314
            CGG L+  SG  +SP YP NYPN+ +C W I       V ++F D Q+EG   C YDY+ 
Sbjct: 145  CGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVA 204

Query: 1315 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYYS 1365
            V  GP  +       C   R  +  S  + + + F SD +I  RGF+A Y+S
Sbjct: 205  VLGGPGPTRG--HHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFS 254


>gi|5031863 galectin 3 binding protein [Homo sapiens]
          Length = 585

 Score =  134 bits (336), Expect = 1e-30
 Identities = 60/101 (59%), Positives = 74/101 (73%)

Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
           +RL +GG   QGRVE+ YRG WGTVCD+ WD +DA+VVCR LG   AT A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
           GPI+LD+V+C+G E+ L  C   GWL  NC+H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  131 bits (330), Expect = 5e-30
 Identities = 72/150 (48%), Positives = 88/150 (58%), Gaps = 11/150 (7%)

Query: 500 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 559
           +RL +GG   QGRVE+ YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 560 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHAS 619
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+  ++RST         H  
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT-NETRST---------HTL 133

Query: 620 TAGSESSLALRLVNGGDR-CQGRVEVLYQG 648
               E S AL  +    R C   + V  QG
Sbjct: 134 DLSRELSEALGQIFDSQRGCDLSISVNVQG 163



 Score =  130 bits (327), Expect = 1e-29
 Identities = 60/111 (54%), Positives = 75/111 (67%)

Query: 889 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 948
           +RL +GG   +GRVE+ YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 949 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTD 999
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+    ++ T D
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLD 134



 Score =  129 bits (325), Expect = 2e-29
 Identities = 61/112 (54%), Positives = 78/112 (69%), Gaps = 1/112 (0%)

Query: 629 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 688
           +RL +GG   QGRVE+ Y+G WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 689 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPD 740
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+ +++R T + D
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT-NETRSTHTLD 134



 Score =  128 bits (322), Expect = 4e-29
 Identities = 58/101 (57%), Positives = 71/101 (70%)

Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
           +RL +GG   +GRVE+ YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  127 bits (319), Expect = 9e-29
 Identities = 57/101 (56%), Positives = 71/101 (70%)

Query: 758 LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 817
           +RL +GG   +GRVE+ Y+G WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 818 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 858
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  126 bits (316), Expect = 2e-28
 Identities = 59/101 (58%), Positives = 69/101 (68%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           +RL +G    QGRVEI YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
           GPI LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  123 bits (308), Expect = 2e-27
 Identities = 53/96 (55%), Positives = 67/96 (69%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
            GRVEI++ G WGTVCD+ W + +A VVCR LG   A  ALG A FG GSGPI LD+V+C+
Sbjct: 35   GRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCT 94

Query: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1241
            GTE++L  C++ GW   NC H  DAGV+C+    ST
Sbjct: 95   GTEASLADCKSLGWLKSNCRHERDAGVVCTNETRST 130


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score =  125 bits (314), Expect = 3e-28
 Identities = 107/377 (28%), Positives = 162/377 (42%), Gaps = 54/377 (14%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CGG L  A+G+FSSP +P  YP N +C+W I  + G  I L   +  +E H  C+FD +E
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLE 1450

Query: 1075 IFDGSLNSSLLLGKICN----DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1130
            I+ G    S  + ++C     +     +S+ N + I F++D+S    GF A + +     
Sbjct: 1451 IYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVT--- 1507

Query: 1131 TLRLVNLNSSYGLCAGRVEIYHG--------GTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182
                       G C G  +   G          + +  D SW I+            R  
Sbjct: 1508 -----------GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIR----------VDRNH 1546

Query: 1183 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG-VICSGNHL-- 1239
              L N +      P     +   G  ST+ +       +  C   + A  ++ SGN L  
Sbjct: 1547 RVLLN-FTDFDLEPQDSCIMAYDGLSSTMSR------LARTCGREQLANPIVSSGNSLFL 1599

Query: 1240 ---STPAPFLNITRPNTDYSCGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNY-R 1294
               S P+      R     +CGG +   S D  SSP +P NYPNN  C W I+ Q     
Sbjct: 1600 RFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNH 1659

Query: 1295 VTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISD 1351
            +T+ F   +LE    C  D++E+ DG +  +PL  R C        TS S+ +++RF+SD
Sbjct: 1660 ITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSD 1719

Query: 1352 HSITRRGFRAEYYSSPS 1368
             SI+  GF     +S S
Sbjct: 1720 SSISAGGFHTTVTASVS 1736



 Score =  125 bits (313), Expect = 4e-28
 Identities = 107/388 (27%), Positives = 168/388 (43%), Gaps = 82/388 (21%)

Query: 1012 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1071
            S+ CGG L  +SGTF SP+YP  Y ++++C W ++ + G    L F +  LE H NC+ D
Sbjct: 1162 STGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLD 1221

Query: 1072 YVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1130
            Y+ ++DG  ++S LL ++C D +  +  SS + M I  R+D   Q  GF A Y       
Sbjct: 1222 YLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR----QT 1277

Query: 1131 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQ----------------EAEVVC- 1173
               +V +N +YG+      I +   +      +WTI+                E  + C 
Sbjct: 1278 CENVVIVNQTYGILE---SIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCS 1334

Query: 1174 ----------RQLG--CGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFS 1221
                      RQ+G  CG  +   G+         +  D V   G     +Q +   WF 
Sbjct: 1335 TDYLELYDGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGV---GRREKGFQMQ---WFV 1388

Query: 1222 HNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNA 1281
            + C           G  LS               + G F S        P +P  YP N 
Sbjct: 1389 YGC-----------GGELSG--------------ATGSFSS--------PGFPNRYPPNK 1415

Query: 1282 KCVWDIEVQ--NNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARG---- 1335
            +C+W I     ++ ++T+   DV+    CN+D +E++ GP   SP IA++C         
Sbjct: 1416 ECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPM 1475

Query: 1336 SFTSSSNFMSIRFISDHSITRRGFRAEY 1363
              +S+ N ++IRF +D SI  RGF A +
Sbjct: 1476 QVSSTGNELAIRFKTDLSINGRGFNASW 1503



 Score =  124 bits (312), Expect = 6e-28
 Identities = 102/368 (27%), Positives = 158/368 (42%), Gaps = 32/368 (8%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CG  L  ++GT  SP +P  YP+   C W I V   + I+L F    LE H+NC+ DY+E
Sbjct: 932  CGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991

Query: 1075 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1133
            ++D   +S   LG+ C  +     TSS N + + F +D      GFL  Y +  S AT  
Sbjct: 992  VYD--TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI-SAATAC 1048

Query: 1134 LVNLNSSYG-LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF-- 1190
            L +     G   +      +   W   C    T++  +++           A+GN Y   
Sbjct: 1049 LQDYTDDLGTFTSPNFPNNYPNNW--ECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDF 1106

Query: 1191 ------GSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAP 1244
                  G    P+ L     S    T+    N+ W                 + + T + 
Sbjct: 1107 LEIRDGGYEKSPL-LGIFYGSNLPPTIISHSNKLWLKF------------KSDQIDTRSG 1153

Query: 1245 FLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQL 1304
            F +     +   CGG L+  SG F SP YP  Y ++++C W ++  +     + F+D  L
Sbjct: 1154 F-SAYWDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHL 1212

Query: 1305 E--GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRA 1361
            E    C  DY+ V+DGP  +S L+ ++C D       SS + M I+  +D     RGF+A
Sbjct: 1213 EHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKA 1272

Query: 1362 EYYSSPSN 1369
            EY  +  N
Sbjct: 1273 EYRQTCEN 1280



 Score =  122 bits (307), Expect = 2e-27
 Identities = 112/398 (28%), Positives = 169/398 (42%), Gaps = 71/398 (17%)

Query: 1005 TTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1064
            TT TA  S+ CGG  + A G F+SP YP  YP N +CVW I  + G R+ L F + +LE 
Sbjct: 1729 TTVTASVSA-CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLED 1787

Query: 1065 HHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSY--NRMTIHFRSDISFQNTGFLA- 1121
              +CS D+VEI +G+     L+G+ C ++  +  SS   + + + F SD S   TGF A 
Sbjct: 1788 SQDCSRDFVEIREGNATGH-LVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQAT 1846

Query: 1122 ---------------------WYNSFPSDATLR-LVNLNSSYGLCAGRVEIYHGGTWGTV 1159
                                 W  ++P ++  +  VN+N+S+ +    +E+         
Sbjct: 1847 FMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCY 1906

Query: 1160 CDDSWTIQEAEVVCRQLG--CGRAVSALGNAYFGSGSGPITL---DDVECSGTESTLWQC 1214
             D         +  R +G  CG    +     F S    +T     D   SG    L   
Sbjct: 1907 YDKLRIYDGPSIHARLIGAYCGTQTES-----FSSTGNSLTFHFYSDSSISGKGFLL--- 1958

Query: 1215 RNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGD----FSS 1270
                WF+          V      L T AP           +CGGFL   +GD      S
Sbjct: 1959 ---EWFA----------VDAPDGVLPTIAP----------GACGGFLR--TGDAPVFLFS 1993

Query: 1271 PFYPGNYPNNAKCVWDIEV-QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARV 1329
            P +P +Y N   C W I+   +   + ++  D++    C YD + + DG    +  +A +
Sbjct: 1994 PGWPDSYSNRVDCTWLIQAPDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVL 2053

Query: 1330 CD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSS 1366
            C     G   S+  +M IRF SD S+TR GF A ++ S
Sbjct: 2054 CGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKS 2091



 Score =  113 bits (283), Expect = 1e-24
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 58/396 (14%)

Query: 1024 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1083
            G  +SP +P  YP+N+   W + VN+ + ++     + +E   NC +D + I+DG    +
Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHA 1920

Query: 1084 LLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLA-WYNSFPSDATLRLVNLNSSYG 1142
             L+G  C    + F+S+ N +T HF SD S    GFL  W+     D  L  +    + G
Sbjct: 1921 RLIGAYCGTQTESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTI----APG 1976

Query: 1143 LCAG-------RVEIYHGG---TWGTVCDDSWTIQ------EAEVVCRQLGCGRAVSALG 1186
             C G        V ++  G   ++    D +W IQ      E  ++   +   R   A  
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDSTVELNILSLDIESHRTC-AYD 2035

Query: 1187 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL 1246
            +     G   +        G E      R+ G +        D+ V  +G + S      
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIP-GPIRSTGEYMF-IRFTSDSSVTRAGFNASFHK--- 2090

Query: 1247 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIF-RDVQLE 1305
                     SCGG+L    G  +SP YP  YP+N  C W + VQ+   + V F +  Q+ 
Sbjct: 2091 ---------SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIP 2141

Query: 1306 GG---CNY-DYIEVFDGPYRSSPLI------ARVCDG-ARGSFTSSSNFMSIRFISDHSI 1354
             G   CN  DY+ + +GP   SP +         C   A  +  +S N M ++FISDHS 
Sbjct: 2142 NGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSN 2201

Query: 1355 TRRGFRAEYYSSP----------SNDSTNLLCLPNH 1380
              +GF+ +Y +              DS   +  PNH
Sbjct: 2202 EGQGFKIKYEAKSLACGGNVYIHDADSAGYVTSPNH 2237



 Score =  112 bits (279), Expect = 4e-24
 Identities = 103/382 (26%), Positives = 161/382 (42%), Gaps = 60/382 (15%)

Query: 1015 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYR-INLGFSNLKLEAHHNCSFDY 1072
            CGG +  +S  T SSP +PA YPNN  C W I+       I L F++ +LE    C+ D+
Sbjct: 1620 CGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDF 1679

Query: 1073 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1131
            VEI DG    + L G+ C  D     TS  + +T+ F SD S    G       F +  T
Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGG-------FHTTVT 1732

Query: 1132 LRLVNLNSSYGLCAGRV------EIYHGGT---WGTVCDD---------SWTIQEAEVVC 1173
              +     ++ +  G        +IY       W  V            S+ +++++   
Sbjct: 1733 ASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCS 1792

Query: 1174 R---QLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDA 1230
            R   ++  G A   L   Y G+ S P+    +       TLW                D 
Sbjct: 1793 RDFVEIREGNATGHLVGRYCGN-SFPLNYSSI----VGHTLW-----------VRFISDG 1836

Query: 1231 GVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQ 1290
                SG+     A F+ I     D   G       G  +SPF+P NYP+N+   W + V 
Sbjct: 1837 ----SGSGTGFQATFMKIF--GNDNIVG-----THGKVASPFWPENYPHNSNYQWTVNVN 1885

Query: 1291 NNYRV--TVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRF 1348
             ++ V   ++  D++    C YD + ++DGP   + LI   C     SF+S+ N ++  F
Sbjct: 1886 ASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCGTQTESFSSTGNSLTFHF 1945

Query: 1349 ISDHSITRRGFRAEYYSSPSND 1370
             SD SI+ +GF  E+++  + D
Sbjct: 1946 YSDSSISGKGFLLEWFAVDAPD 1967



 Score =  106 bits (265), Expect = 2e-22
 Identities = 103/398 (25%), Positives = 163/398 (40%), Gaps = 53/398 (13%)

Query: 997  TTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPA--YYPNNAKCVWEIEVNSGYRIN 1054
            T   W  +   T  P   CGG+L  ++ TF+SP   +   Y  N  CVW I       I+
Sbjct: 3139 TAKGWKMSFRQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIH 3198

Query: 1055 LGFSNLKLEA---HHNCSFDYVEIFDGSLNSSLLLGKICNDTRQI-FTSSYNRMTIHFRS 1110
            L F+   LEA      C +DYV+++DG   ++ L G  C  T    F SS N +T+ F S
Sbjct: 3199 LTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFIS 3258

Query: 1111 DISFQNTGFLAWYNSFPS------DATLRLVNLNS--------SYGLCAGRVEI-YHGGT 1155
            D++ +  GF A Y           +AT    N++S         + +C   ++   H   
Sbjct: 3259 DLTLEREGFNATYTIMDMPCGGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQV 3318

Query: 1156 WGTVCDDSWTIQEAEVVCRQ--LGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ 1213
              TV    W +Q     C Q  L    +    GN+ F       +   V  S   + +  
Sbjct: 3319 KITV----WALQLTSQDCTQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVI 3374

Query: 1214 CRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFY 1273
             +              +GV+   + +S       I   N DY       +  G+  SP +
Sbjct: 3375 FK--------------SGVVNRNSRMSFT---YQIADCNRDY------HKAFGNLRSPGW 3411

Query: 1274 PGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCD 1331
            P NY N+  C   +    N+ +++ F  + +E    C  D++EV +G   +SPL+ + C 
Sbjct: 3412 PDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCG 3471

Query: 1332 G-ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPS 1368
                    S +N + +RF SD   + RG+   + SSPS
Sbjct: 3472 TLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPS 3509



 Score =  104 bits (260), Expect = 6e-22
 Identities = 109/416 (26%), Positives = 164/416 (39%), Gaps = 49/416 (11%)

Query: 976  HNCGHHEDAGVICSATQIN----STTTDWWHPTTTTTARPSSNCGGFLFY----ASGTFS 1027
            H CG H  + +  S  Q+     S  ++            S  CGG ++     ++G  +
Sbjct: 2174 HFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGNVYIHDADSAGYVT 2233

Query: 1028 SPSYPAYYPNNAKCVWEIEVNSGYRINLGFSN-LKLEAHHNCSFDYVEIFDGSLNSSLLL 1086
            SP++P  YP +A C+W +      RI L F +   +E   NC+ +Y+E+ DG  + + +L
Sbjct: 2234 SPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPIL 2293

Query: 1087 GKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCA 1145
             K C  +      SS   M + FRSD S  + GF A Y                S   C 
Sbjct: 2294 SKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY----------------SIAQCG 2337

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCR-QLGCGRAVSALGNAYFGSGSGPITLDDVE- 1203
            GRV     G  G V     +I    +  R  L C   +  L   Y         L +   
Sbjct: 2338 GRVP----GQSGVV----ESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSG 2389

Query: 1204 CSGTESTLWQCRNRG-WFSHNCNHREDAGVICSGNHL--------STPAPFLNITRPNTD 1254
            C      +W     G      C +     +  S N          S  A    +   ++ 
Sbjct: 2390 CEKDFVEIWDNHTSGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSM 2449

Query: 1255 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCNYDY 1312
              CGG L    G F+SP YP   P+   C W I      R+T++F +++L     CN ++
Sbjct: 2450 EECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEH 2509

Query: 1313 IEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSS 1366
            + VF+G   +SP + ++C     S    SS N M + F +D S    GF A Y SS
Sbjct: 2510 VIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSS 2565



 Score =  102 bits (255), Expect = 2e-21
 Identities = 104/391 (26%), Positives = 141/391 (36%), Gaps = 57/391 (14%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CGG L    G+  SP YP  YP    CVW +  +    +   F  L LE H +C+ DY+E
Sbjct: 590  CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLE 649

Query: 1075 IFDGSLNSSLLLGKICNDTRQI----FTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1130
            I DG L    LLGK C  T  +     T  + R  IHF SD    + GF   Y + PSD 
Sbjct: 650  IRDGPLYQDPLLGKFCT-TFSVPPLQTTGPFAR--IHFHSDSQISDQGFHITYLTSPSDL 706

Query: 1131 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV-------- 1182
                         C G      G  +       +T     V   +   G  +        
Sbjct: 707  R------------CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVE 754

Query: 1183 ----SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNH 1238
                S     Y     G   L  V  +GT S +    N  W       + DA V      
Sbjct: 755  LQCQSDSSQNYIEVRDGETLLGKVCGNGTISHIKSITNSVWI----RFKIDASV------ 804

Query: 1239 LSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVI 1298
                A F    R     +CG  L+   G   SPF+P  YP    C W I    +  + + 
Sbjct: 805  --EKASF----RAVYQVACGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLN 857

Query: 1299 FR--DVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSF-TSSSNFMSIRFISDHSIT 1355
            F   ++     C  DY+E+       SP   + C     SF TS  NF+ + F+   S  
Sbjct: 858  FTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTE 917

Query: 1356 RRGFRAEYYSSP------SNDSTNLLCLPNH 1380
              GF A++ +          +ST  +  P H
Sbjct: 918  NHGFMAKFSAEDLACGEILTESTGTIQSPGH 948



 Score =  102 bits (255), Expect = 2e-21
 Identities = 169/737 (22%), Positives = 264/737 (35%), Gaps = 134/737 (18%)

Query: 739  PDTWPTS------RASTAGS--ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCD-DYWDT 789
            PD+  TS      R  T GS   S   LR  +  + C G +    QGS GT    +Y + 
Sbjct: 2416 PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDL----QGSIGTFTSPNYPNP 2471

Query: 790  NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 849
            N    +C      W ++AP   +       ++ +++R + H S                 
Sbjct: 2472 NPHGRICE-----WRITAPEGRRI-----TLMFNNLRLATHPSC---------------- 2505

Query: 850  HEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS 909
            + +  ++ +  +S S        + N+      S +++ +     G R  G     Y  S
Sbjct: 2506 NNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSS 2565

Query: 910  WGTVCDDSW-DTNDANVVC----------RQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 958
               VC  S  +T + N             R L C W +S P     G  S  I  +D   
Sbjct: 2566 EDAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQ---GNSSISIHFEDFYL 2622

Query: 959  SGNESYLWSCPHKGWLTHNCGHHEDAGV--ICSATQ-----INSTTTDWWHPTTTTTAR- 1010
              ++   +       L    G  +   +  +C  ++     +   +  W H  T      
Sbjct: 2623 ESHQDCQFDV-----LEFRVGDADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEH 2677

Query: 1011 -------PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLE 1063
                     ++CGG     SG  +SP+YP  Y +   C   +E   G+ I L FS+  +E
Sbjct: 2678 IGFHAKYSFTDCGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIE 2737

Query: 1064 AHHNCSFDYVEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1122
             H  C++D V + +G    S ++G+ C N   +   S  N++ + F SD S Q  GF A 
Sbjct: 2738 PHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYAT 2797

Query: 1123 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAE------VVCRQL 1176
            +N+     TL           C G   I+H    GT+    W     E            
Sbjct: 2798 WNT----QTLG----------CGG---IFHSDN-GTIRSPHWPQNFPENSRCSWTAITHK 2839

Query: 1177 GCGRAVSALGNAYFGSGSGPITLDDVEC-SGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
                 +S   N    SG G      V+  +GTE       ++   +  C +     VI  
Sbjct: 2840 SKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEV-----DKALLATGCGNVAPGPVITP 2894

Query: 1236 GNHLSTPAPFLNITRPNTDYS------CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 1289
             N  +  A F +   P   +S      CG   + PSG   SP YP  Y NN  C + IE 
Sbjct: 2895 SNTFT--AVFQSQEAPAQGFSASFVSRCGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEA 2952

Query: 1290 QNNYRVTVIFRDVQLE------GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNF 1343
                 V + F    LE      G C  D + +  G    S   A VC     +  + +  
Sbjct: 2953 NPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGP 3012

Query: 1344 MSIRFISDHSITRRGFRAEY----YSSPSNDSTNLLCLPNHMQA------------SVSR 1387
            + + F S+  IT  GF+  Y         N S+ ++  P +  A            +VS 
Sbjct: 3013 VLLNFYSNEQITDFGFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSD 3072

Query: 1388 SYLQSLGFSASDLVIST 1404
              +  L FS  D+V ST
Sbjct: 3073 DKVIELKFSDFDVVPST 3089



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 99/383 (25%), Positives = 156/383 (40%), Gaps = 57/383 (14%)

Query: 1012 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1071
            +  CGG     SG   SP+YP+ Y +N  C W I V+  +R+ L F++  LE   +C   
Sbjct: 1507 TGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMA 1566

Query: 1072 YVEIFDGSLNSSLLLGKICNDTRQI--FTSSYNRMTIHFRSDISFQNTGFLAWY------ 1123
            Y    DG  ++   L + C   +      SS N + + F+S  S QN GF A +      
Sbjct: 1567 Y----DGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGG 1622

Query: 1124 ----NSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQ---- 1175
                +SF + ++ R      +   C+  ++        T+    + ++ +    R     
Sbjct: 1623 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1682

Query: 1176 LGCGRAVSALGNAYFGSGSG-PITLDDVECSGTESTLWQCRNRGWFSHNCNHR--EDAGV 1232
            L  G   + L   Y G+    PIT                     FS     R   D+ +
Sbjct: 1683 LDGGHEDAPLRGRYCGTDMPHPITS--------------------FSSALTLRFVSDSSI 1722

Query: 1233 ICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNN 1292
               G H +  A            +CGG      G F+SP YP  YP N +CVW+I     
Sbjct: 1723 SAGGFHTTVTASVS---------ACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPG 1773

Query: 1293 YRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS--SNFMSIRF 1348
             R+ + F   QLE    C+ D++E+ +G   +  L+ R C  +     SS   + + +RF
Sbjct: 1774 NRLQLSFISFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRF 1832

Query: 1349 ISDHSITRRGFRAEYYSSPSNDS 1371
            ISD S +  GF+A +     ND+
Sbjct: 1833 ISDGSGSGTGFQATFMKIFGNDN 1855



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 107/435 (24%), Positives = 168/435 (38%), Gaps = 54/435 (12%)

Query: 994  NSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1053
            +S  +D     T  T+     CGG      G    P     + +  +CV+ ++   G +I
Sbjct: 687  DSQISDQGFHITYLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQI 746

Query: 1054 NLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDI 1112
             + F++++L+   + S +Y+E+ DG      LLGK+C N T     S  N + I F+ D 
Sbjct: 747  QINFTHVELQCQSDSSQNYIEVRDGET----LLGKVCGNGTISHIKSITNSVWIRFKIDA 802

Query: 1113 SFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVV 1172
            S +   F A Y     D       + S +        +Y G      C   WTI + +  
Sbjct: 803  SVEKASFRAVYQVACGDELTGEGVIRSPFF-----PNVYPGER---TC--RWTIHQPQ-- 850

Query: 1173 CRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGV 1232
                     V  L    F  GS      D    G+ S L    N+ +    C     + +
Sbjct: 851  -------SQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY----CGTDIPSFI 899

Query: 1233 ICSGNHLSTPAPFLNITRPN--------TDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCV 1284
                N L       + T  +         D +CG  L++ +G   SP +P  YP+   C 
Sbjct: 900  TSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCT 959

Query: 1285 WDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSS 1341
            W I VQ N+ + ++F    LE    C  DY+EV+D    +S  + R C      S TSS 
Sbjct: 960  WHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSG 1017

Query: 1342 NFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLV 1401
            N + + F++D  +   GF   Y +     S    CL         + Y   LG   S   
Sbjct: 1018 NSLMLVFVTDSDLAYEGFLINYEAI----SAATACL---------QDYTDDLGTFTSPNF 1064

Query: 1402 ISTWNGYYECRPQIT 1416
             + +   +EC  +IT
Sbjct: 1065 PNNYPNNWECIYRIT 1079



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 99/377 (26%), Positives = 153/377 (40%), Gaps = 51/377 (13%)

Query: 1015 CGGFLFYASGT--FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
            CGGFL          SP +P  Y N   C W I+      + L   +L +E+H  C++D 
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESHRTCAYDS 2036

Query: 1073 VEIFDGSLNSSLLLGKICNDTRQI---FTSSYNRMTIHFRSDISFQNTGFLAWYN----- 1124
            + I DG  N +  L  +C   R+I     S+   M I F SD S    GF A ++     
Sbjct: 2037 LVIRDGDNNLAQQLAVLCG--REIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGG 2094

Query: 1125 ---------SFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQ 1175
                     + P        NLN     C+  V +  G T     +  + I   +  C Q
Sbjct: 2095 YLHADRGIITSPKYPETYPSNLN-----CSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQ 2149

Query: 1176 LGCGRAVSALGNAYFGSGSGPITLDDVEC-SGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
                  V   G        GP   +   C S   STL+   N+ +     +H  +     
Sbjct: 2150 --GDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEG---- 2203

Query: 1235 SGNHLSTPAPFLNITRPNTDYSCGGFL----SQPSGDFSSPFYPGNYPNNAKCVWDIEVQ 1290
             G  +   A  L         +CGG +    +  +G  +SP +P NYP +A C+W +   
Sbjct: 2204 QGFKIKYEAKSL---------ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAP 2254

Query: 1291 NNYRVTVIFR---DVQLEGGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSI 1346
               R+ + F    D+++   C  +Y+E+ DG    +P++++ C      S  SS   M +
Sbjct: 2255 PETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYL 2314

Query: 1347 RFISDHSITRRGFRAEY 1363
            RF SD+S T  GF+A+Y
Sbjct: 2315 RFRSDNSPTHVGFKAKY 2331



 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 97/386 (25%), Positives = 148/386 (38%), Gaps = 59/386 (15%)

Query: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
            CG  L    G   SP +P  YP    C W I       I L F+  ++ +  +C  DYVE
Sbjct: 817  CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875

Query: 1075 IFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1133
            I   S+  S    K C  D     TS YN + + F    S +N GF+A +          
Sbjct: 876  IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF---------- 925

Query: 1134 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA---EVVCRQLGCGRAVSALGNAYF 1190
                 S+  L  G +          + + + TIQ      V    + C   +    N   
Sbjct: 926  -----SAEDLACGEI----------LTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLI 970

Query: 1191 GSGSGPITLD-DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNIT 1249
                    L+    C+     ++   +       C       +  SGN L      + + 
Sbjct: 971  HLMFETFHLEFHYNCTNDYLEVYDTDSETSLGRYCGKSIPPSLTSSGNSL------MLVF 1024

Query: 1250 RPNTDYSCGGFL----------------SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNY 1293
              ++D +  GFL                +   G F+SP +P NYPNN +C++ I V+   
Sbjct: 1025 VTDSDLAYEGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQ 1084

Query: 1294 RVTVIFRDVQLE---GGCNYDYIEVFDGPYRSSPLIARVCDGAR--GSFTSSSNFMSIRF 1348
             + V F +  LE   G    D++E+ DG Y  SPL+  +  G+    +  S SN + ++F
Sbjct: 1085 LIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLG-IFYGSNLPPTIISHSNKLWLKF 1143

Query: 1349 ISDHSITRRGFRAEYYSSPSNDSTNL 1374
             SD   TR GF A +  S +    NL
Sbjct: 1144 KSDQIDTRSGFSAYWDGSSTGCGGNL 1169



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 87/372 (23%), Positives = 154/372 (41%), Gaps = 29/372 (7%)

Query: 1011 PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF 1070
            P   CG  L   +G+FS  S    Y ++  C W I+   G  + + F+  +LE+  NC  
Sbjct: 470  PQQVCGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529

Query: 1071 DYVEIFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGF-LAWYNSFPS 1128
            ++++++DG  +S+  LG+ C  +      SS N +  H  S+      GF + W    P 
Sbjct: 530  EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 589

Query: 1129 DATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV----SA 1184
               +    L   YG         + G +    D  W +  +  +      G         
Sbjct: 590  CGGI----LTGPYGSIKSP---GYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDD 642

Query: 1185 LGNAYFGSGSGPITLDDVECS-GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPA 1243
                Y     GP+  D +     T  ++   +  G F+   +   D+ +   G H++   
Sbjct: 643  CNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFA-RIHFHSDSQISDQGFHIT--- 698

Query: 1244 PFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQ 1303
                +T P +D  CGG  + P G+   P   G + +  +CV+ ++     ++ + F  V+
Sbjct: 699  ---YLTSP-SDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVE 754

Query: 1304 L--EGGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFR 1360
            L  +   + +YIEV DG      L+ +VC +G      S +N + IRF  D S+ +  FR
Sbjct: 755  LQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFR 810

Query: 1361 AEYYSSPSNDST 1372
            A Y  +  ++ T
Sbjct: 811  AVYQVACGDELT 822



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 4/113 (3%)

Query: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1314
            CGG L    G F+SP YPG YPNN  C W +       VT+ F  + ++  G C  +Y+ 
Sbjct: 3511 CGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570

Query: 1315 VFDGPYRSSPLIARVCDG--ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYS 1365
            ++DGP  SSP     C G  +   F +SSN + I+F +D++     FR  + S
Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTWDS 3623



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 45/115 (39%), Positives = 63/115 (54%), Gaps = 5/115 (4%)

Query: 1014 NCGGFLFYASGTFSSPSYP-AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
            +CGG   ++SG  +SP+Y  A YPN+  C++ I V+    I L FS+  +    +CS DY
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095

Query: 1073 VEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF 1126
            + I+DG+  S  LLGK C   R     SS N M + F++D SFQ      W  SF
Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTA--KGWKMSF 3147



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 5/132 (3%)

Query: 994  NSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1053
            +S T+D  +    T++   S CGG L+   G+F+SP YP  YPNN  C W +   +G  +
Sbjct: 3492 DSVTSDRGYEIIWTSS--PSGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLV 3549

Query: 1054 NLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQI--FTSSYNRMTIHFRSD 1111
             + F  + ++   +C  +Y+ ++DG   SS   G  C     I  F +S N++ I F +D
Sbjct: 3550 TINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHAD 3609

Query: 1112 ISFQNTGF-LAW 1122
             + + + F L W
Sbjct: 3610 YARRPSAFRLTW 3621



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 35/112 (31%), Positives = 61/112 (54%), Gaps = 4/112 (3%)

Query: 1256 SCGGFLSQPSGDFSSPFYP-GNYPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCNYDY 1312
            SCGG  +  SG  +SP Y   +YPN+  C++ I V ++  + + F D  +     C++DY
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095

Query: 1313 IEVFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEY 1363
            + ++DG   S PL+ + C   R  +  SS+N M + F +D   T +G++  +
Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSF 3147



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 11/206 (5%)

Query: 932  CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP--HKGWLTHNCGHHEDAGVICS 989
            C W + +P + +       + L    C+ N   L   P  H       CG +  A V   
Sbjct: 3306 CTWVIDSPPHQQVKITVWALQLTSQDCTQNYLQLQDSPQGHGNSRFQFCGRNASA-VPVF 3364

Query: 990  ATQINSTTTDWWHPTTTTTARPS-----SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWE 1044
             + +++    +        +R S     ++C      A G   SP +P  Y N+  C   
Sbjct: 3365 YSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYHKAFGNLRSPGWPDNYDNDKDCTVT 3424

Query: 1045 IEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYN 1102
            +     + I+L F +L +E    C  D++E+ +GS ++S LLGK C       +F S  N
Sbjct: 3425 LTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVF-SQNN 3483

Query: 1103 RMTIHFRSDISFQNTGFLAWYNSFPS 1128
             + + F+SD    + G+   + S PS
Sbjct: 3484 ELYLRFKSDSVTSDRGYEIIWTSSPS 3509



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 12/123 (9%)

Query: 1014 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF--- 1070
            +CGG+L    G  +SP YP  YP+N  C W + V SG  I + F       + + S    
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150

Query: 1071 DYVEIFDGSLNSSLLL------GKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1122
            DY+ + +G    S  L      G  C    +  +FTS  N+M + F SD S +  GF   
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSD-NQMFVQFISDHSNEGQGFKIK 2209

Query: 1123 YNS 1125
            Y +
Sbjct: 2210 YEA 2212



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 8/108 (7%)

Query: 1261 LSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYIEVFDG 1318
            ++Q  G   S  YP  Y  N  C W I       V   F    LE    C+ DY+E++DG
Sbjct: 1284 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1343

Query: 1319 PYRSSPLIARVC--DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 1364
            P +    + R C  D      T+SS    +          +GF+ +++
Sbjct: 1344 PRQ----MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWF 1387


>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
          Length = 782

 Score =  122 bits (305), Expect = 4e-27
 Identities = 63/113 (55%), Positives = 73/113 (64%), Gaps = 1/113 (0%)

Query: 352 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
           AS A  +  + L    G     GRVEV   G WGTVCDDSW+ S A VVCRQLG  +A  
Sbjct: 664 ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723

Query: 412 APGNARFGQ-GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
           A   A FGQ GS PI+LDDVRC+G+E  L  C HNG  +HNC+H EDAGV+CS
Sbjct: 724 AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  118 bits (295), Expect = 5e-26
 Identities = 62/113 (54%), Positives = 72/113 (63%), Gaps = 1/113 (0%)

Query: 618 ASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 677
           AS A  +  + L    G     GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A+ 
Sbjct: 664 ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723

Query: 678 APGNARFGQ-GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 729
           A   A FGQ GS PI+LDDVRC+G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 724 AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  117 bits (293), Expect = 9e-26
 Identities = 57/91 (62%), Positives = 65/91 (71%), Gaps = 1/91 (1%)

Query: 245 GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ-GSGPIVLDDVRC 303
           GRVEV   G WGTVCDD W+ + A VVCRQLG  +A+ A   A+FGQ GS PI+LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 304 SGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           +G E  L  C HNG  THNC H EDAGV+CS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  116 bits (290), Expect = 2e-25
 Identities = 57/95 (60%), Positives = 65/95 (68%), Gaps = 1/95 (1%)

Query: 113 GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQ-GSGPIALDDVRC 171
           GRVE+   G WGTVCDDSW+ + A VVCRQLG  +A+ A   A FGQ GS PI LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQP 206
           +G E  L  C HNG  +HNC H EDAGV+CS   P
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQNP 780



 Score =  116 bits (290), Expect = 2e-25
 Identities = 57/91 (62%), Positives = 65/91 (71%), Gaps = 1/91 (1%)

Query: 511 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ-GSGPIVLDDVRC 569
           GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A+ A   A FGQ GS PI+LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 570 SGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
           +G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (289), Expect = 3e-25
 Identities = 69/146 (47%), Positives = 82/146 (56%), Gaps = 16/146 (10%)

Query: 729 SASQSRPTPSP---DTWPTSR------------ASTAGSESTLALRLVNGGDRCRGRVEV 773
           +A+   PTP P      P SR            AS A  +  + L    G     GRVEV
Sbjct: 631 TAAPPAPTPRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSGRVEV 690

Query: 774 LYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ-GSGPIVLDDVRCSGHES 832
              G WGTVCDD W+ + A VVCRQLG  +A+ A   A+FGQ GS PI+LDDVRC+G E 
Sbjct: 691 FVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCAGWER 750

Query: 833 YLWSCPHNGWLSHNCGHHEDAGVICS 858
            L  C HNG  +HNC H EDAGV+CS
Sbjct: 751 NLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (288), Expect = 4e-25
 Identities = 57/91 (62%), Positives = 64/91 (70%), Gaps = 1/91 (1%)

Query: 900 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ-GSGPIVLDDVRC 958
           GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A+ A   A FGQ GS PI+LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 959 SGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           +G E  L  C H G  THNC H EDAGV+CS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (287), Expect = 5e-25
 Identities = 55/92 (59%), Positives = 65/92 (70%), Gaps = 1/92 (1%)

Query: 1145 AGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-SGSGPITLDDVE 1203
            +GRVE++ GG WGTVCDDSW I  A VVCRQLG   AV A+  A FG  GS PI LDDV 
Sbjct: 685  SGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVR 744

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            C+G E  L +C++ G  +HNC H EDAGV+CS
Sbjct: 745  CAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776


>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
          Length = 495

 Score =  114 bits (285), Expect = 8e-25
 Identities = 53/109 (48%), Positives = 67/109 (61%)

Query: 621 AGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPG 680
           +G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 681 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 729
            ARFGQG+G I +DDV C G E  ++ C  + W   NCGH+EDA V C+
Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  112 bits (281), Expect = 2e-24
 Identities = 53/108 (49%), Positives = 66/108 (61%)

Query: 493 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 552
           G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 553 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
           ARFGQG+G I +DDV C G E  ++ C  + W   NCGH+EDA V C+
Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  112 bits (280), Expect = 3e-24
 Identities = 53/108 (49%), Positives = 63/108 (58%)

Query: 882 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 941
           G E+ + +RLVNG     GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 942 ARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           ARFGQG+G I +DDV C G E  ++ C    W   NCGH EDA V C+
Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  112 bits (279), Expect = 4e-24
 Identities = 52/110 (47%), Positives = 66/110 (60%)

Query: 93  AEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 152
           A G ++ + +RLVNG G  +GRVE+ +   WGTVCDD WD  D +VVCR LG        
Sbjct: 384 ASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVY 443

Query: 153 GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
             A FGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 444 RTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  110 bits (276), Expect = 9e-24
 Identities = 52/109 (47%), Positives = 66/109 (60%)

Query: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
           +G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
            ARFGQG+G I +DDV C G E  ++ C  + W   NC H+EDA V C+
Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  110 bits (275), Expect = 1e-23
 Identities = 52/108 (48%), Positives = 65/108 (60%)

Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           G E+ + +RLVNG     GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           A+FGQG+G I +DDV C G E  ++ C  + W   NCGH+EDA V C+
Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  109 bits (273), Expect = 2e-23
 Identities = 52/109 (47%), Positives = 65/109 (59%)

Query: 750 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 809
           +G E+ + +RLVNG     GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 810 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 858
            A+FGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  101 bits (252), Expect = 5e-21
 Identities = 46/102 (45%), Positives = 59/102 (57%)

Query: 1134 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1193
            ++ L +  G   GRVE+YH   WGTVCDD W  ++ +VVCR LG          A FG G
Sbjct: 392  MIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQG 451

Query: 1194 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            +G I +DDV C GTE T+++C    W   NC H EDA V C+
Sbjct: 452  TGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493


>gi|5803080 macrophage receptor with collagenous structure [Homo
           sapiens]
          Length = 520

 Score =  110 bits (276), Expect = 9e-24
 Identities = 55/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 358 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNAR 417
           E+S+++R+V   +R  GR EV Y G+WGT+CDD W  SDA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 418 F--GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (276), Expect = 9e-24
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 495 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNAR 554
           E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLG-----YSKGRAL 471

Query: 555 F--GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (274), Expect = 1e-23
 Identities = 56/111 (50%), Positives = 70/111 (63%), Gaps = 9/111 (8%)

Query: 226 EGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 285
           E  E+S+++R+V  G   RGR EV Y G+WGT+CDD W  +DA V CR LG      + G
Sbjct: 416 ERGENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKG 468

Query: 286 NAQF--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
            A +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 469 RALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (274), Expect = 1e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 624 ESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 683
           E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 684 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 729
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (270), Expect = 4e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 753 ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQ 812
           E+++++R+V  G   RGR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419 ENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 813 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 858
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (269), Expect = 6e-23
 Identities = 54/108 (50%), Positives = 68/108 (62%), Gaps = 9/108 (8%)

Query: 884 ESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 943
           E+S+++R+V  G   RGR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419 ENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 944 F--GQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           +  G G+G I LD+V+C G ES LWSC    W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  107 bits (268), Expect = 7e-23
 Identities = 48/92 (52%), Positives = 60/92 (65%), Gaps = 7/92 (7%)

Query: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF--GSGSGPITLDDVE 1203
            GR E+Y+ GTWGT+CDD W   +A V CR LG  +     G A +  G+G+G I LD+V+
Sbjct: 433  GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSK-----GRALYKVGAGTGQIWLDNVQ 487

Query: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            C GTESTLW C    W  H+C+H EDAGV CS
Sbjct: 488  CRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  107 bits (267), Expect = 1e-22
 Identities = 53/120 (44%), Positives = 71/120 (59%), Gaps = 9/120 (7%)

Query: 85  ESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLG 144
           E  ++    E  ++ +++R+V    R  GR E+ Y G+WGT+CDD W  +DA V CR LG
Sbjct: 407 EQGVKGEKGERGENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLG 464

Query: 145 CGWAMSAPGNAWF--GQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
                 + G A +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 465 Y-----SKGRALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519


>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
           sapiens]
          Length = 451

 Score =  105 bits (262), Expect = 4e-22
 Identities = 52/120 (43%), Positives = 67/120 (55%), Gaps = 4/120 (3%)

Query: 614 PTSHASTAGSESSLA----LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQ 669
           P       GS ++L     +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR 
Sbjct: 331 PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390

Query: 670 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 729
           LG     +    A FGQG+GPI L++V C G ES +  C    W +  C HSEDAGV C+
Sbjct: 391 LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  105 bits (261), Expect = 5e-22
 Identities = 49/101 (48%), Positives = 61/101 (60%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           +RLV G G  +GRVEIL+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
           GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  104 bits (260), Expect = 6e-22
 Identities = 49/101 (48%), Positives = 60/101 (59%)

Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
           +RLV G     GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           GPI L++V C G ES +  C    W T  C HSEDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  104 bits (259), Expect = 8e-22
 Identities = 60/149 (40%), Positives = 77/149 (51%), Gaps = 10/149 (6%)

Query: 324 GHSEDAGVICSAPQSRPTPS-----PDTWPTSHASTAGSESSLA----LRLVNGGDRCQG 374
           G   D G I   P SR  P       ++ P       GS ++L     +RLV G    +G
Sbjct: 303 GLKGDRGAI-GFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEG 361

Query: 375 RVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 434
           RVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+GPI L++V C G
Sbjct: 362 RVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFG 421

Query: 435 YESYLWSCPHNGWLSHNCQHSEDAGVICS 463
            ES +  C    W +  C HSEDAGV C+
Sbjct: 422 RESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  104 bits (259), Expect = 8e-22
 Identities = 52/120 (43%), Positives = 66/120 (55%), Gaps = 4/120 (3%)

Query: 743 PTSRASTAGSESTLA----LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 798
           P  +    GS +TL     +RLV G     GRVE+L+ G WGT+CDD W+     VVCR 
Sbjct: 331 PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390

Query: 799 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 858
           LG     +    A FGQG+GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 391 LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  103 bits (258), Expect = 1e-21
 Identities = 48/101 (47%), Positives = 60/101 (59%)

Query: 889 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 948
           +RLV G     GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 949 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
           GPI L++V C G ES +  C  + W T  C H EDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  103 bits (257), Expect = 1e-21
 Identities = 48/101 (47%), Positives = 60/101 (59%)

Query: 500 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 559
           +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR LG          A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 560 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600
           GPI L++V C G ES +  C    W +  C HSEDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (255), Expect = 2e-21
 Identities = 47/101 (46%), Positives = 63/101 (62%)

Query: 1135 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1194
            V L    G   GRVEI H G WGT+CDD W ++  +VVCR LG     +    A+FG G+
Sbjct: 350  VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 1195 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
            GPI L++V C G ES++ +C+ R W +  C+H EDAGV C+
Sbjct: 410  GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,246,361
Number of Sequences: 37866
Number of extensions: 3807798
Number of successful extensions: 11698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 9170
Number of HSP's gapped (non-prelim): 1264
length of query: 1662
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1546
effective length of database: 13,855,062
effective search space: 21419925852
effective search space used: 21419925852
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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