BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] (1788 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 3830 0.0 gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 3752 0.0 gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 3425 0.0 gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 3425 0.0 gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 3172 0.0 gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H... 856 0.0 gi|44889963 CD163 antigen isoform b [Homo sapiens] 783 0.0 gi|44662834 CD163 antigen isoform a [Homo sapiens] 783 0.0 gi|18152779 scavenger receptor cysteine rich domain containing, ... 512 e-144 gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] 494 e-139 gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 481 e-135 gi|4506143 neurotrypsin precursor [Homo sapiens] 362 1e-99 gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens] 296 9e-80 gi|5174411 CD5 molecule-like [Homo sapiens] 269 2e-71 gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] 269 2e-71 gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] 261 4e-69 gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] 256 1e-67 gi|194018748 CD6 molecule [Homo sapiens] 247 8e-65 gi|22547221 tolloid-like 1 [Homo sapiens] 151 6e-36 gi|6912724 tolloid-like 2 [Homo sapiens] 144 6e-34 gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 138 4e-32 gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 138 4e-32 gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 138 4e-32 gi|72384339 CUB domain containing protein 2 [Homo sapiens] 136 2e-31 gi|5031863 galectin 3 binding protein [Homo sapiens] 134 6e-31 gi|126091152 cubilin [Homo sapiens] 125 4e-28 gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] 122 4e-27 gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] 114 8e-25 gi|5803080 macrophage receptor with collagenous structure [Homo ... 110 9e-24 gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo... 105 4e-22 >gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] Length = 1788 Score = 3830 bits (9932), Expect = 0.0 Identities = 1788/1788 (100%), Positives = 1788/1788 (100%) Query: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV Sbjct: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60 Query: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR Sbjct: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 Query: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS Sbjct: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 Query: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG Sbjct: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 Query: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD Sbjct: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 Query: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ Sbjct: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 Query: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT Sbjct: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480 Query: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA Sbjct: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 Query: 541 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLP 600 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLP Sbjct: 541 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLP 600 Query: 601 TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 660 TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA Sbjct: 601 TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 660 Query: 661 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED Sbjct: 661 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720 Query: 721 AGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 780 AGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC Sbjct: 721 AGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 780 Query: 781 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 840 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL Sbjct: 781 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 840 Query: 841 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVL 900 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVL Sbjct: 841 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVL 900 Query: 901 YQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYL 960 YQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYL Sbjct: 901 YQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYL 960 Query: 961 WSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNG 1020 WSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNG Sbjct: 961 WSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNG 1020 Query: 1021 GDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1080 GDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD Sbjct: 1021 GDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1080 Query: 1081 DVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSN 1140 DVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSN Sbjct: 1081 DVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSN 1140 Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE Sbjct: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 Query: 1201 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL 1260 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL Sbjct: 1201 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL 1260 Query: 1261 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1320 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS Sbjct: 1261 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1320 Query: 1321 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTD 1380 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTD Sbjct: 1321 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTD 1380 Query: 1381 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIE 1440 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIE Sbjct: 1381 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIE 1440 Query: 1441 VFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 1500 VFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL Sbjct: 1441 VFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 1500 Query: 1501 LCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQ 1560 LCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQ Sbjct: 1501 LCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQ 1560 Query: 1561 ADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQV 1620 ADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQV Sbjct: 1561 ADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQV 1620 Query: 1621 EEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVAS 1680 EEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVAS Sbjct: 1621 EEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVAS 1680 Query: 1681 PYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVC 1740 PYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVC Sbjct: 1681 PYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVC 1740 Query: 1741 RAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1788 RAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR Sbjct: 1741 RAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1788 >gi|148539840 deleted in malignant brain tumors 1 isoform a precursor [Homo sapiens] Length = 1785 Score = 3752 bits (9729), Expect = 0.0 Identities = 1756/1788 (98%), Positives = 1766/1788 (98%), Gaps = 3/1788 (0%) Query: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV Sbjct: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60 Query: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR Sbjct: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 Query: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS Sbjct: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 Query: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG Sbjct: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 Query: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD Sbjct: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360 Query: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ Sbjct: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 Query: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT Sbjct: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480 Query: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 LPASTVGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWA Sbjct: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 Query: 541 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLP 600 M APGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGHSEDAGVICSA Q P Sbjct: 541 MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRP 600 Query: 601 TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 660 TP P +WP+SHA + G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDA Sbjct: 601 TP-SPDTWPTSHA--STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 657 Query: 661 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720 NVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHED Sbjct: 658 NVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 717 Query: 721 AGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 780 AGVICSA+QS+ TP PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVC Sbjct: 718 AGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 777 Query: 781 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 840 DD WDTNDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL Sbjct: 778 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 837 Query: 841 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVL 900 SHNCGH EDAGVICSASQS+PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVL Sbjct: 838 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVL 897 Query: 901 YQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYL 960 YQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYL Sbjct: 898 YQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYL 957 Query: 961 WSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNG 1020 WSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNG Sbjct: 958 WSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNG 1017 Query: 1021 GDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1080 GDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD Sbjct: 1018 GDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1077 Query: 1081 DVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSN 1140 DVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSN Sbjct: 1078 DVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSN 1137 Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1197 Query: 1201 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL 1260 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL Sbjct: 1198 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL 1257 Query: 1261 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1320 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS Sbjct: 1258 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1317 Query: 1321 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTD 1380 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTD Sbjct: 1318 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTD 1377 Query: 1381 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIE 1440 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIE Sbjct: 1378 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIE 1437 Query: 1441 VFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 1500 VFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL Sbjct: 1438 VFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNL 1497 Query: 1501 LCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQ 1560 LCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQ Sbjct: 1498 LCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQ 1557 Query: 1561 ADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQV 1620 ADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQV Sbjct: 1558 ADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQV 1617 Query: 1621 EEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVAS 1680 EEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVAS Sbjct: 1618 EEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVAS 1677 Query: 1681 PYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVC 1740 PYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVC Sbjct: 1678 PYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVC 1737 Query: 1741 RAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1788 RAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR Sbjct: 1738 RAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1785 >gi|148539844 deleted in malignant brain tumors 1 isoform c precursor [Homo sapiens] Length = 2403 Score = 3425 bits (8882), Expect = 0.0 Identities = 1605/1696 (94%), Positives = 1630/1696 (96%), Gaps = 10/1696 (0%) Query: 95 GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154 GS+S L LRLVNG RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWA SAPGN Sbjct: 716 GSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 775 Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214 A FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICS +Q + T P++ Sbjct: 776 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDT 835 Query: 215 WPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 274 WP + T G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDT+DANVVCRQ Sbjct: 836 WP---TSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQ 892 Query: 275 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 LGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNC HSEDAGVICS Sbjct: 893 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 952 Query: 335 APQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 392 A S TPSPDT PT AST GSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSW Sbjct: 953 AAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSW 1012 Query: 393 DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNC 452 DT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNC Sbjct: 1013 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1072 Query: 453 QHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYR 512 HSEDAGVICSA+ S TPSPDT PT AST GSESSLALRLVNGGDRCQGRVEVLYR Sbjct: 1073 GHSEDAGVICSASQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYR 1130 Query: 513 GSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWS 572 GSWGTVCDD WDTNDANVVCRQLGCGWAM APGNARFGQGSGPIVLDDVRCSG+ESYLWS Sbjct: 1131 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1190 Query: 573 CPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGG 632 CPHNGWLSHNCGH EDAGVICSA Q PTP P +WP+SHA + G ESSLALRLVNGG Sbjct: 1191 CPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSHA--STAGSESSLALRLVNGG 1247 Query: 633 DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 692 DRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD Sbjct: 1248 DRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 1307 Query: 693 VRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESS 752 VRCSGHESYLWSCP+NGWLSHNCGHHEDAGVICSA+QS+ TP PDTWPTSHASTAGSESS Sbjct: 1308 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESS 1367 Query: 753 LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ 812 LALRLVNGGDRCQGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWA SAPGNARFGQ Sbjct: 1368 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQ 1427 Query: 813 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSR 872 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICSASQS+PTPSPDTWPTSR Sbjct: 1428 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSR 1487 Query: 873 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 932 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS Sbjct: 1488 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1547 Query: 933 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP 992 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP Sbjct: 1548 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP 1607 Query: 993 RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV 1052 RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV Sbjct: 1608 RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV 1667 Query: 1053 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 1112 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV Sbjct: 1668 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 1727 Query: 1113 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE 1172 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE Sbjct: 1728 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE 1787 Query: 1173 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI 1232 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI Sbjct: 1788 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI 1847 Query: 1233 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1292 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI Sbjct: 1848 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1907 Query: 1293 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1352 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH Sbjct: 1908 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1967 Query: 1353 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD 1412 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD Sbjct: 1968 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD 2027 Query: 1413 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI 1472 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI Sbjct: 2028 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI 2087 Query: 1473 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN 1532 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN Sbjct: 2088 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN 2147 Query: 1533 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS 1592 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS Sbjct: 2148 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS 2207 Query: 1593 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD 1652 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD Sbjct: 2208 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD 2267 Query: 1653 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL 1712 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL Sbjct: 2268 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL 2327 Query: 1713 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL 1772 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL Sbjct: 2328 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL 2387 Query: 1773 GPIQLQTPPRREEEPR 1788 GPIQLQTPPRREEEPR Sbjct: 2388 GPIQLQTPPRREEEPR 2403 Score = 2360 bits (6116), Expect = 0.0 Identities = 1141/1401 (81%), Positives = 1180/1401 (84%), Gaps = 81/1401 (5%) Query: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV Sbjct: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60 Query: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR Sbjct: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 Query: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS Sbjct: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 Query: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG Sbjct: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 Query: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD Sbjct: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360 Query: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ Sbjct: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 Query: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS DTLPTIT Sbjct: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS----------DTLPTIT 470 Query: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA Sbjct: 471 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 530 Query: 541 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLP 600 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS Sbjct: 531 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS------ 584 Query: 601 TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 660 GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA Sbjct: 585 ------------------GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 626 Query: 661 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED Sbjct: 627 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 686 Query: 721 AGVICSAAQSRSTPRPDTWP--TSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 778 AGVICSAAQSRSTPRPDT T ST GSESSL LRLVNG DRCQGRVEVLY+GSWGT Sbjct: 687 AGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 746 Query: 779 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 838 VCDDSWDTNDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG Sbjct: 747 VCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 806 Query: 839 WLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVE 898 WLSHNCGH EDAGVICS SQSRPTPSPDTWPTS ASTAG ES+LALRLVNGGDRC+GRVE Sbjct: 807 WLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVE 866 Query: 899 VLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 958 VLY+GSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ES Sbjct: 867 VLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYES 926 Query: 959 YLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLV 1018 YLWSCPHNGWLSHNC H EDAGVICSAA S STP PDT T LPA TVGSESSLALRLV Sbjct: 927 YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLV 986 Query: 1019 NGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 1078 NGGDRC+GRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV Sbjct: 987 NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 1046 Query: 1079 LDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPTTTTTARP 1137 LDDVRCSG+ESYLWSCPH GWL+HNCGH EDAGVICSA+Q T + D W + +TA Sbjct: 1047 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGS 1106 Query: 1138 SSN-----------CGGFL-FYASGTFSSPSYPAYYPNNAK-------CVWEIEVNSGYR 1178 S+ C G + G++ + + N+A C W + R Sbjct: 1107 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAR 1166 Query: 1179 INLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRM 1230 G + L+ CS ++ N L G IC+ ++ T S + Sbjct: 1167 FGQGSGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTW 1225 Query: 1231 TIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW 1290 S + S LRLVN C GRVE+ + G+WGTVCDD W Sbjct: 1226 PTSHASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYW 1270 Query: 1291 TIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNC 1350 +A VVCRQLGCG A SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC Sbjct: 1271 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1330 Query: 1351 NHREDAGVICSGNHLS-TPAP 1370 H EDAGVICS + TP+P Sbjct: 1331 GHHEDAGVICSASQSQPTPSP 1351 Score = 604 bits (1558), Expect = e-172 Identities = 320/540 (59%), Positives = 352/540 (65%), Gaps = 55/540 (10%) Query: 863 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 922 PS T ++ A GS+S LALRLVNG RC+GRVE+LY+GSWGTVCDD WDTNDANVVC Sbjct: 83 PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140 Query: 923 RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 982 RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI Sbjct: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200 Query: 983 CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 1041 CSAAQ QST RP++W + + P T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD Sbjct: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260 Query: 1042 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 1101 D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT Sbjct: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320 Query: 1102 HNCGHHEDAGVICSATQINSTTT-DWWHPTTTTTARPSSN-----------CGG---FLF 1146 HNCGH EDAGVICSA Q T + D W + +TA P S+ C G L+ Sbjct: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380 Query: 1147 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1201 S GT S+ N C W R G + L+ CS + Sbjct: 381 RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD-DVRCSGYESYL 439 Query: 1202 FDGSLNSSLL--------LGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1253 + N L G IC+DT T + + Sbjct: 440 WSCPHNGWLSHNCQHSEDAGVICSDTLPTITLPASTV--------------------GSE 479 Query: 1254 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1313 S LRLVN C GRVE+ + G+WGTVCDDSW +A VVCRQLGCG A+ A GN Sbjct: 480 SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 536 Query: 1314 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLN 1373 A FG GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG S +N Sbjct: 537 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVN 596 >gi|148539842 deleted in malignant brain tumors 1 isoform b precursor [Homo sapiens] Length = 2413 Score = 3425 bits (8882), Expect = 0.0 Identities = 1605/1696 (94%), Positives = 1630/1696 (96%), Gaps = 10/1696 (0%) Query: 95 GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154 GS+S L LRLVNG RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWA SAPGN Sbjct: 726 GSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 785 Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214 A FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICS +Q + T P++ Sbjct: 786 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDT 845 Query: 215 WPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 274 WP + T G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDT+DANVVCRQ Sbjct: 846 WP---TSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQ 902 Query: 275 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 LGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNC HSEDAGVICS Sbjct: 903 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962 Query: 335 APQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 392 A S TPSPDT PT AST GSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSW Sbjct: 963 AAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSW 1022 Query: 393 DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNC 452 DT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNC Sbjct: 1023 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1082 Query: 453 QHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYR 512 HSEDAGVICSA+ S TPSPDT PT AST GSESSLALRLVNGGDRCQGRVEVLYR Sbjct: 1083 GHSEDAGVICSASQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140 Query: 513 GSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWS 572 GSWGTVCDD WDTNDANVVCRQLGCGWAM APGNARFGQGSGPIVLDDVRCSG+ESYLWS Sbjct: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200 Query: 573 CPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGG 632 CPHNGWLSHNCGH EDAGVICSA Q PTP P +WP+SHA + G ESSLALRLVNGG Sbjct: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSHA--STAGSESSLALRLVNGG 1257 Query: 633 DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 692 DRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD Sbjct: 1258 DRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 1317 Query: 693 VRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESS 752 VRCSGHESYLWSCP+NGWLSHNCGHHEDAGVICSA+QS+ TP PDTWPTSHASTAGSESS Sbjct: 1318 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESS 1377 Query: 753 LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ 812 LALRLVNGGDRCQGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWA SAPGNARFGQ Sbjct: 1378 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQ 1437 Query: 813 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSR 872 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICSASQS+PTPSPDTWPTSR Sbjct: 1438 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSR 1497 Query: 873 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 932 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS Sbjct: 1498 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1557 Query: 933 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP 992 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP Sbjct: 1558 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP 1617 Query: 993 RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV 1052 RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV Sbjct: 1618 RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV 1677 Query: 1053 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 1112 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV Sbjct: 1678 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 1737 Query: 1113 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE 1172 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE Sbjct: 1738 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE 1797 Query: 1173 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI 1232 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI Sbjct: 1798 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI 1857 Query: 1233 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1292 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI Sbjct: 1858 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1917 Query: 1293 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1352 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH Sbjct: 1918 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1977 Query: 1353 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD 1412 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD Sbjct: 1978 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD 2037 Query: 1413 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI 1472 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI Sbjct: 2038 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI 2097 Query: 1473 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN 1532 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN Sbjct: 2098 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN 2157 Query: 1533 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS 1592 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS Sbjct: 2158 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS 2217 Query: 1593 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD 1652 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD Sbjct: 2218 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD 2277 Query: 1653 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL 1712 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL Sbjct: 2278 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL 2337 Query: 1713 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL 1772 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL Sbjct: 2338 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL 2397 Query: 1773 GPIQLQTPPRREEEPR 1788 GPIQLQTPPRREEEPR Sbjct: 2398 GPIQLQTPPRREEEPR 2413 Score = 2390 bits (6195), Expect = 0.0 Identities = 1151/1401 (82%), Positives = 1190/1401 (84%), Gaps = 71/1401 (5%) Query: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV Sbjct: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60 Query: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR Sbjct: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 Query: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS Sbjct: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 Query: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG Sbjct: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 Query: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD Sbjct: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360 Query: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ Sbjct: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 Query: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT Sbjct: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480 Query: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA Sbjct: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 Query: 541 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLP 600 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS Sbjct: 541 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS------ 594 Query: 601 TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 660 GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA Sbjct: 595 ------------------GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 636 Query: 661 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED Sbjct: 637 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 696 Query: 721 AGVICSAAQSRSTPRPDTWP--TSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 778 AGVICSAAQSRSTPRPDT T ST GSESSL LRLVNG DRCQGRVEVLY+GSWGT Sbjct: 697 AGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 756 Query: 779 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 838 VCDDSWDTNDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG Sbjct: 757 VCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 816 Query: 839 WLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVE 898 WLSHNCGH EDAGVICS SQSRPTPSPDTWPTS ASTAG ES+LALRLVNGGDRC+GRVE Sbjct: 817 WLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVE 876 Query: 899 VLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 958 VLY+GSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ES Sbjct: 877 VLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYES 936 Query: 959 YLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLV 1018 YLWSCPHNGWLSHNC H EDAGVICSAA S STP PDT T LPA TVGSESSLALRLV Sbjct: 937 YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLV 996 Query: 1019 NGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 1078 NGGDRC+GRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV Sbjct: 997 NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 1056 Query: 1079 LDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPTTTTTARP 1137 LDDVRCSG+ESYLWSCPH GWL+HNCGH EDAGVICSA+Q T + D W + +TA Sbjct: 1057 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGS 1116 Query: 1138 SSN-----------CGGFL-FYASGTFSSPSYPAYYPNNAK-------CVWEIEVNSGYR 1178 S+ C G + G++ + + N+A C W + R Sbjct: 1117 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAR 1176 Query: 1179 INLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRM 1230 G + L+ CS ++ N L G IC+ ++ T S + Sbjct: 1177 FGQGSGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTW 1235 Query: 1231 TIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW 1290 S + S LRLVN C GRVE+ + G+WGTVCDD W Sbjct: 1236 PTSHASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYW 1280 Query: 1291 TIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNC 1350 +A VVCRQLGCG A SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC Sbjct: 1281 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1340 Query: 1351 NHREDAGVICSGNHLS-TPAP 1370 H EDAGVICS + TP+P Sbjct: 1341 GHHEDAGVICSASQSQPTPSP 1361 Score = 602 bits (1552), Expect = e-171 Identities = 319/535 (59%), Positives = 355/535 (66%), Gaps = 35/535 (6%) Query: 863 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 922 PS T ++ A GS+S LALRLVNG RC+GRVE+LY+GSWGTVCDD WDTNDANVVC Sbjct: 83 PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140 Query: 923 RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 982 RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI Sbjct: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200 Query: 983 CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 1041 CSAAQ QST RP++W + + P T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD Sbjct: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260 Query: 1042 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 1101 D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT Sbjct: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320 Query: 1102 HNCGHHEDAGVICSATQINSTTT-DWWHPTTTTTARPSSN-----------CGG---FLF 1146 HNCGH EDAGVICSA Q T + D W + +TA P S+ C G L+ Sbjct: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380 Query: 1147 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1201 S GT S+ N C W R G + L+ + E Sbjct: 381 RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGY---ES 437 Query: 1202 FDGSLNSSLLLGKICN---DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATL 1258 + S + L C D I +++++ T S + A S L Sbjct: 438 YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST---PSPDTLPTITLPASTVGSESSLAL 494 Query: 1259 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1318 RLVN C GRVE+ + G+WGTVCDDSW +A VVCRQLGCG A+ A GNA FG Sbjct: 495 RLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ 551 Query: 1319 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLN 1373 GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG S +N Sbjct: 552 GSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVN 606 >gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] Length = 1662 Score = 3172 bits (8224), Expect = 0.0 Identities = 1490/1571 (94%), Positives = 1509/1571 (96%), Gaps = 10/1571 (0%) Query: 226 EGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 285 EGS+S LALRLVNG RC+GRVE+LYRGSWGTVCDD WDTNDANVVCRQLGCGWAMSAPG Sbjct: 94 EGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPG 153 Query: 286 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPD 345 NA FGQGSGPI LDDVRCSGHESYLWSCPHNGWL+HNCGH EDAGVICSA Q + T P+ Sbjct: 154 NAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPE 213 Query: 346 TWP---TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCR 402 +WP + T GSESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDT+DANVVCR Sbjct: 214 SWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCR 273 Query: 403 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 462 QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNC HSEDAGVIC Sbjct: 274 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVIC 333 Query: 463 SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 522 SA S TPSPDT PT AST GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS Sbjct: 334 SAPQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 391 Query: 523 WDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN 582 WDT+DANVVCRQLGCGWA APGNARFGQGSGPIVLDDVRCSG ESYLWSCPHNGWLSHN Sbjct: 392 WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 451 Query: 583 CGHSEDAGVICSALQWLPTPI-----RPRSWPSSHALQTCKGPESSLALRLVNGGDRCQG 637 C HSEDAGVICSA TP R + P+ + G ESSLALRLVNGGDRCQG Sbjct: 452 CQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQG 511 Query: 638 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 697 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA APGNARFGQGSGPIVLDDVRCSG Sbjct: 512 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSG 571 Query: 698 HESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRL 757 +ESYLWSCP+NGWLSHNCGH EDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRL Sbjct: 572 NESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRL 631 Query: 758 VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 817 VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI Sbjct: 632 VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 691 Query: 818 VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAG 877 VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAG Sbjct: 692 VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAG 751 Query: 878 SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 937 SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA Sbjct: 752 SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 811 Query: 938 QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 997 QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW Sbjct: 812 QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 871 Query: 998 LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 1057 LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG Sbjct: 872 LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 931 Query: 1058 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 1117 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT Sbjct: 932 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 991 Query: 1118 QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY 1177 QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY Sbjct: 992 QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGY 1051 Query: 1178 RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1237 RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD Sbjct: 1052 RINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1111 Query: 1238 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV 1297 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV Sbjct: 1112 ISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEV 1171 Query: 1298 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG 1357 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG Sbjct: 1172 VCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG 1231 Query: 1358 VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN 1417 VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN Sbjct: 1232 VICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQN 1291 Query: 1418 NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD 1477 NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD Sbjct: 1292 NYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISD 1351 Query: 1478 HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC 1537 HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC Sbjct: 1352 HSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYEC 1411 Query: 1538 RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ 1597 RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ Sbjct: 1412 RPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRMLQ 1471 Query: 1598 NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL 1657 NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL Sbjct: 1472 NTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDL 1531 Query: 1658 YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF 1717 YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF Sbjct: 1532 YVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARF 1591 Query: 1718 RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL 1777 RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL Sbjct: 1592 RFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQL 1651 Query: 1778 QTPPRREEEPR 1788 QTPPRREEEPR Sbjct: 1652 QTPPRREEEPR 1662 Score = 2031 bits (5263), Expect = 0.0 Identities = 948/1008 (94%), Positives = 965/1008 (95%), Gaps = 12/1008 (1%) Query: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV Sbjct: 1 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60 Query: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR Sbjct: 61 AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120 Query: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS Sbjct: 121 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180 Query: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG Sbjct: 181 CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240 Query: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD Sbjct: 241 DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS Sbjct: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 Query: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ Sbjct: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420 Query: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP------D 474 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP D Sbjct: 421 GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480 Query: 475 TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 534 TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ Sbjct: 481 TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540 Query: 535 LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594 LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS Sbjct: 541 LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600 Query: 595 ALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 654 A Q TP RP +WP+SHA + G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDS Sbjct: 601 AAQSRSTP-RPDTWPTSHA--STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDS 657 Query: 655 WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHN 714 WDTNDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHN Sbjct: 658 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 717 Query: 715 CGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQG 774 CGH EDAGVICSA+QSR TP PDTWPTS ASTAGSES+LALRLVNGGDRC+GRVEVLYQG Sbjct: 718 CGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG 777 Query: 775 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 834 SWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSGHESYLWSC Sbjct: 778 SWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSC 837 Query: 835 PHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSR--ASTAGSESTLALRLVNGGDR 892 PHNGWLSHNCGH EDAGVICSA+QS+ TP PDTW T+ A T GSES+LALRLVNGGDR Sbjct: 838 PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDR 897 Query: 893 CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVR 952 CRGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVR Sbjct: 898 CRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 957 Query: 953 CSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTT 1000 CSG+ESYLWSCPH GWL+HNCGHHEDAGVICSA Q ST D W T Sbjct: 958 CSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPT 1004 Score = 596 bits (1537), Expect = e-170 Identities = 320/531 (60%), Positives = 354/531 (66%), Gaps = 36/531 (6%) Query: 83 PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140 PS T ++ A GS+S LALRLVNG RC+GRVE+LY+GSWGTVCDD WDTNDANVVC Sbjct: 737 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 796 Query: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200 RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI Sbjct: 797 RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 856 Query: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260 CSAAQ QST RP++W + + P T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD Sbjct: 857 CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 915 Query: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320 D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT Sbjct: 916 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 975 Query: 321 HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY 380 HNCGH EDAGVICSA Q T + D W + +TA S+ C G L+ Sbjct: 976 HNCGHHEDAGVICSATQINST-TTDWWHPTTTTTARPSSN-----------CGG---FLF 1020 Query: 381 RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD-DVRCS--GYES 437 S GT S+ N C W R G + L+ CS E Sbjct: 1021 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1075 Query: 438 YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST---PSPDTLPTITLPASTVGSESSLAL 494 + S + L C D I +++++ T S + A S L Sbjct: 1076 FDGSLNSSLLLGKIC---NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATL 1132 Query: 495 RLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ 551 RLVN C GRVE+ + G+WGTVCDDSW +A VVCRQLGCG A+ A GNA FG Sbjct: 1133 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1192 Query: 552 GSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTP 602 GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICS L TP Sbjct: 1193 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG-NHLSTP 1242 >gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo sapiens] Length = 1453 Score = 856 bits (2212), Expect = 0.0 Identities = 485/1285 (37%), Positives = 647/1285 (50%), Gaps = 201/1285 (15%) Query: 92 VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151 ++ + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T + VVC+QLGC ++ + Sbjct: 38 ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97 Query: 152 PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208 FGQ G I LDDV C G+ES LW C H W SHNC HGED GV C Sbjct: 98 ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----- 149 Query: 209 TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268 E++L LRLV+G + C GRVEV ++ WGT+CDD W+ N A Sbjct: 150 --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189 Query: 269 NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328 VVCRQLGC + + G PI LDD+ C G+E LW+C H GW H+C H+ED Sbjct: 190 AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249 Query: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388 + C S L LRLV G +RC GRVE+ +G WGTVC Sbjct: 250 VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287 Query: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448 W+ + A+VVC+QLGCG A G GS + LD V CSG ES+LW C H+G + Sbjct: 288 HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347 Query: 449 SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508 + +C H D VICS + L LRL +G + C GRVE Sbjct: 348 NFDCLHQNDVSVICS------------------------DGADLELRLADGSNNCSGRVE 383 Query: 509 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNES 568 V W T+CD +W A VVC+QLGC +++ A+ + I ++ + C+GNES Sbjct: 384 VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNES 443 Query: 569 YLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRL 628 LW C ++G C DAGVICS ++ L LRL Sbjct: 444 ALWDCTYDGKAKRTCFRRSDAGVICS-------------------------DKADLDLRL 478 Query: 629 VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPI 688 V C GR+EV Y+G WGTVC D W T +A VVC+QLGCG G F + SGPI Sbjct: 479 VGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPI 538 Query: 689 VLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAG 748 LDDV C G+ES +W C ++GW HNC H ED V CS Sbjct: 539 WLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS---------------------- 576 Query: 749 SESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 808 +++ LRLV G +RC GR+EV +QG WGTVCDD W++ A VVC QL C ++ G Sbjct: 577 GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLG 636 Query: 809 RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTW 868 G G I LDDV C G ES LWSC ++GW +++C HSED GVICS Sbjct: 637 NASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS------------- 683 Query: 869 PTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCG 928 S + LRLV G RC G+VEV QG+ G +C + W N A VVCRQL CG Sbjct: 684 ---------DASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECG 734 Query: 929 WAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQS 988 A+ F + + I++ + C+G E+ LW C W C + +A +ICSA + Sbjct: 735 SAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQ 794 Query: 989 QSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTND 1048 RLV C GRVEV + +W +VCD + + Sbjct: 795 P--------------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHA 828 Query: 1049 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHE 1108 ANV+CR+L CG A+S FG+G+G + +C G+E++L CP C H Sbjct: 829 ANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSR 888 Query: 1109 DAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKC 1167 + GV+CS T S C G + G + S + P +A+ Sbjct: 889 EVGVVCS------------RYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARV 936 Query: 1168 VWEIEVNSGYRIN------LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---ND 1218 + +++ G ++ +G ++++ H + D + ++L C N Sbjct: 937 LCR-QLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNT 994 Query: 1219 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF--PSDATLRLVNLNSSYGLCAGRVEI 1276 I T S + +++S + ++ D LRLV+ +S CAGRVEI Sbjct: 995 VSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEI 1051 Query: 1277 YHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTEST 1336 YH G WGT+CDD W + +A VVC++LGCG A +A +A+FG GSGPI LDD+ C+G ES Sbjct: 1052 YHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESH 1111 Query: 1337 LWQCRNRGWFSHNCNHREDAGVICS 1361 LWQC +RGW H+C H+EDAGVICS Sbjct: 1112 LWQCPSRGWGQHDCRHKEDAGVICS 1136 Score = 715 bits (1845), Expect = 0.0 Identities = 402/1039 (38%), Positives = 522/1039 (50%), Gaps = 163/1039 (15%) Query: 100 LALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQ 159 L LRLV C GR+E+ Y+G WGTVC D W T +A VVC+QLGCG M G +F + Sbjct: 474 LDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKE 533 Query: 160 GSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRI 219 SGPI LDDV C G+ES +W C H+GW HNC H ED V CS Sbjct: 534 ASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG---------------- 577 Query: 220 SPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279 +++ LRLV G +RC GR+EV ++G WGTVCDD W++ A VVC QL C Sbjct: 578 ---------DATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPS 628 Query: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339 ++ G G G I LDDV C G ES LWSC ++GW ++C HSED GVICS Sbjct: 629 SIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS----- 683 Query: 340 PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399 S + LRLV G RC G+VEV +G+ G +C + W + A V Sbjct: 684 -----------------DASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEV 726 Query: 400 VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459 VCRQL CG A F + + I++ + C+G E+ LW C W C + +A Sbjct: 727 VCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEAS 786 Query: 460 VICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 519 +ICSA RLV C GRVEV + +W +VC Sbjct: 787 LICSAHRQ--------------------------PRLVGADMPCSGRVEVKHADTWRSVC 820 Query: 520 DDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWL 579 D + + ANV+CR+L CG A+ FG+G+G + +C G+E++L CP Sbjct: 821 DSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHP 880 Query: 580 SHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRV 639 C HS + GV+CS +RLVNG +C G+V Sbjct: 881 EDTCIHSREVGVVCSRYT---------------------------DVRLVNGKSQCDGQV 913 Query: 640 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 699 E+ G WG++CD WD DA V+CRQL CG A S G G+ S + C G+E Sbjct: 914 EINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNE 973 Query: 700 SYLWSCPNNGWLSHNCGHHEDAGVICSAAQSR---------STPRPDTWPTSHASTAGSE 750 S L +C + C H VIC+ + ++ S P P A + Sbjct: 974 SLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLED 1033 Query: 751 SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 810 L RLV+G RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A +A +A F Sbjct: 1034 KRL--RLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHF 1091 Query: 811 GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPT 870 G+GSGPI LDD+ C+G ES+LW CP GW H+C H EDAGVICS Sbjct: 1092 GEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS--------------- 1136 Query: 871 SRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 930 + L L + C GR+EV Y G+WG+V T A +VCRQLGCG Sbjct: 1137 -------EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGEN 1189 Query: 931 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQS 990 GSG + +DD++C +W C W + S Sbjct: 1190 GVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW-----------------ERRIS 1232 Query: 991 TPRPDTWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSWGTVCDDSWDTNDA 1049 +P +TW+T E + +R GGD C GRVE+ + GSWGTVCDDSWD +A Sbjct: 1233 SPAEETWIT---------CEDRIRVR---GGDTECSGRVEIWHAGSWGTVCDDSWDLAEA 1280 Query: 1050 NVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED 1109 VVC+QLGCG A++A +A FGQG+G I LDD+RC GNES+LW C K W +CGH ED Sbjct: 1281 EVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKED 1340 Query: 1110 AGVICSATQINSTTTDWWH 1128 AGV CS + S H Sbjct: 1341 AGVRCSGQSLKSLNASSGH 1359 Score = 548 bits (1411), Expect = e-155 Identities = 324/878 (36%), Positives = 420/878 (47%), Gaps = 133/878 (15%) Query: 490 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 549 + L LRLVNG C G VEV ++G WGTVCDD W+T + VVC+QLGC ++ RF Sbjct: 44 TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100 Query: 550 GQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPR 606 GQ G I LDDV C GNES LW C H W SHNC H ED GV C Sbjct: 101 GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149 Query: 607 SWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 666 E++L LRLV+G + C GRVEV ++ WGT+CDD W+ N A VVCRQ Sbjct: 150 --------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQ 195 Query: 667 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726 LGC + + G PI LDD+ C G+E LW+C + GW +H+C H+ED + C Sbjct: 196 LGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY 255 Query: 727 AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 786 S L LRLV G +RC GRVE+ QG WGTVC W+ Sbjct: 256 ----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNN 293 Query: 787 NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 846 A+VVC+QLGCG A+ G GS + LD V CSG+ES+LW C H+G ++ +C H Sbjct: 294 AAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLH 353 Query: 847 SEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWG 906 D VICS + L LRL +G + C GRVEV W Sbjct: 354 QNDVSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWW 391 Query: 907 TVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHN 966 T+CD W A VVC+QLGC +++ A+ + I ++ + C+G+ES LW C ++ Sbjct: 392 TICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYD 451 Query: 967 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1026 G C DAGVICS ++ L LRLV C G Sbjct: 452 GKAKRTCFRRSDAGVICS------------------------DKADLDLRLVGAHSPCYG 487 Query: 1027 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1086 R+EV Y+G WGTVC D W T +A VVC+QLGCG M G F + SGPI LDDV C G Sbjct: 488 RLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIG 547 Query: 1087 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL- 1145 NES +W C H GW HNC H ED V C S W S+ C G L Sbjct: 548 NESNIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRCSGRLE 597 Query: 1146 FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGS 1205 Y G + + + A V I +G N + + + + D S Sbjct: 598 VYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIWLDDVS 651 Query: 1206 LNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNS 1265 + +D S + D+ G + S SD LRLV +S Sbjct: 652 CDGDE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRLVGGSS 697 Query: 1266 SYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITL 1325 CAG+VE+ G G +C + W + AEVVCRQL CG A+ +F + I + Sbjct: 698 R---CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILM 754 Query: 1326 DDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1363 + C+G E++LW C W C+ +A +ICS + Sbjct: 755 SNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792 Score = 499 bits (1286), Expect = e-141 Identities = 288/766 (37%), Positives = 381/766 (49%), Gaps = 113/766 (14%) Query: 98 SGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWF 157 S + LRLV G RC G+VE+ +G+ G +C + W N A VVCRQL CG A+ F Sbjct: 686 SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHF 745 Query: 158 GQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSA-AQPQSTLRPESWP 216 + + I + + C+G E+ LW C W C +A +ICSA QP Sbjct: 746 TERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP---------- 795 Query: 217 VRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276 RLV C GRVEV + +W +VCD + + ANV+CR+L Sbjct: 796 ------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELN 837 Query: 277 CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336 CG A+S FG+G+G + +C G E++L CP C HS + GV+CS Sbjct: 838 CGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY 897 Query: 337 QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD 396 +RLVNG +C G+VE+ G WG++CD WD D Sbjct: 898 TD------------------------VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPED 933 Query: 397 ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSE 456 A V+CRQL CG A S G G+ S + C G ES L +C + C H Sbjct: 934 ARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGN 993 Query: 457 DAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLA-------LRLVNGGDRCQGRVEV 509 VIC+ S + P L ++ P + E S LRLV+G RC GRVE+ Sbjct: 994 TVSVICTG--SLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEI 1051 Query: 510 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESY 569 + G WGT+CDD WD +DA+VVC++LGCG A A +A FG+GSGPI LDD+ C+G ES+ Sbjct: 1052 YHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESH 1111 Query: 570 LWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLV 629 LW CP GW H+C H EDAGVICS ++L L Sbjct: 1112 LWQCPSRGWGQHDCRHKEDAGVICSEF-------------------------TALRLYSE 1146 Query: 630 NGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV 689 + C GR+EV Y G+WG+V + T A +VCRQLGCG GSG + Sbjct: 1147 TETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMW 1206 Query: 690 LDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGS 749 +DD++C +W C + W + S+P +TW T Sbjct: 1207 VDDIQCPKTHISIWQCLSAPW-----------------ERRISSPAEETWITCED----- 1244 Query: 750 ESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 809 +R+ G C GRVE+ + GSWGTVCDDSWD +A VVC+QLGCG A++A +A Sbjct: 1245 ----RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDAS 1300 Query: 810 FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 855 FGQG+G I LDD+RC G+ES+LW C W +CGH EDAGV CS Sbjct: 1301 FGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346 Score = 307 bits (787), Expect = 5e-83 Identities = 175/415 (42%), Positives = 221/415 (53%), Gaps = 67/415 (16%) Query: 63 GSPISLESTLESTVAEGSL----IPSESTLE----STVAEGSD----SGLALRLVNGDGR 110 G+P + S + GSL P + + S V EGS LRLV+GD R Sbjct: 985 GAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR 1044 Query: 111 CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVR 170 C GRVEI + G WGT+CDD WD +DA+VVC++LGCG A +A +A FG+GSGPI LDD+ Sbjct: 1045 CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLN 1104 Query: 171 CSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSES 230 C+G ES+LW CP GW H+C H EDAGVICS E +R+ TE Sbjct: 1105 CTGMESHLWQCPSRGWGQHDCRHKEDAGVICS----------EFTALRLYSETETES--- 1151 Query: 231 SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 290 C GR+EV Y G+WG+V T A +VCRQLGCG Sbjct: 1152 ------------CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSK 1199 Query: 291 QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR--PTPSPDTWP 348 GSG + +DD++C +W C SAP R +P+ +TW Sbjct: 1200 TGSGFMWVDDIQCPKTHISIWQC-------------------LSAPWERRISSPAEETWI 1240 Query: 349 TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGW 408 T +R+ G C GRVE+ + GSWGTVCDDSWD ++A VVC+QLGCG Sbjct: 1241 TCED---------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291 Query: 409 ATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463 A +A +A FGQG+G I LDD+RC G ES+LW C W +C H EDAGV CS Sbjct: 1292 ALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346 Score = 138 bits (348), Expect = 4e-32 Identities = 59/98 (60%), Positives = 73/98 (74%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329 C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ Sbjct: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1367 C G ES LW C + W +C H+EDAGV CSG L + Sbjct: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352 Score = 77.0 bits (188), Expect = 2e-13 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%) Query: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1317 +RLVN S C G+VEI G WG++CD W ++A V+CRQL CG A+S G Y G Sbjct: 900 VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956 Query: 1318 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 1376 S + C G ES L C+ + C H VIC+G+ P L N++ Sbjct: 957 ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016 Query: 1377 P 1377 P Sbjct: 1017 P 1017 Score = 71.6 bits (174), Expect = 6e-12 Identities = 33/91 (36%), Positives = 51/91 (56%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329 CAGR+E+++ GTWG+V + T A +VCRQLGCG +GSG + +DD++ Sbjct: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360 C T ++WQC + W + E+ + C Sbjct: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242 >gi|44889963 CD163 antigen isoform b [Homo sapiens] Length = 1121 Score = 783 bits (2023), Expect = 0.0 Identities = 442/1141 (38%), Positives = 588/1141 (51%), Gaps = 182/1141 (15%) Query: 14 WGQVLSTGGWIPRTTDYASLIPSEVPLDTTV-----AEGSPFPSELTLESTVAEGSPISL 68 WG V + G W + + S+I +++ T + A S + ++ G+ +L Sbjct: 72 WGTVCNNG-W---SMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESAL 127 Query: 69 ESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCD 128 + S + T ++GS+ L +RL G C GR+EI ++G WGTVCD Sbjct: 128 WDCKHDGWGKHSNCTHQQDAGVTCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCD 185 Query: 129 DSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLS 188 D+++ + A+V+CRQL CG A+S G++ FG+GSGPI DD+ C+G+ES LW+C H GW Sbjct: 186 DNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGK 245 Query: 189 HNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVE 248 HNC H EDAGVICS + L+LRLV+G C GR+E Sbjct: 246 HNCDHAEDAGVICSKG-------------------------ADLSLRLVDGVTECSGRLE 280 Query: 249 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 308 V ++G WGT+CDD WD+ DA V C+QLGC A++A G +G G I LD V C GHE Sbjct: 281 VRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEP 340 Query: 309 YLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 368 +W C H+ W H C H+EDAGV CS S L LRL G Sbjct: 341 AVWQCKHHEWGKHYCNHNEDAGVTCS----------------------DGSDLELRLRGG 378 Query: 369 GDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIV 426 G RC G VEV + G VCD W +A+VVCRQLGCG A TS ++ + + Sbjct: 379 GSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLF 438 Query: 427 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTV 486 L C+G E+ LW C + W C H E+A + CSA Sbjct: 439 LSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------- 477 Query: 487 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 546 RLV G C GRVEV + +WG++CD + A+V+CR+L CG + G Sbjct: 478 -------PRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGG 530 Query: 547 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPR 606 A FG+G+G I ++ +C G+ES+L CP C HS D GV+CS Sbjct: 531 AHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYT--------- 581 Query: 607 SWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 666 +RLVNG C+GRVE+ G+WG++C+ WD DA+V+C+Q Sbjct: 582 ------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQ 623 Query: 667 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726 L CG A S PG ARFG+G+G I C+G E ++ CP + C + A VICS Sbjct: 624 LKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683 Query: 727 AAQSR------STPRPDTWPT-SHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTV 779 QS+ S+ T PT S S LRLVNGG RC GRVE+ ++GSWGT+ Sbjct: 684 GNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTI 743 Query: 780 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGW 839 CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G ES +W C +GW Sbjct: 744 CDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGW 803 Query: 840 LSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR--CRGRV 897 NC H EDAGVICS ++LRL + R C GR+ Sbjct: 804 GQQNCRHKEDAGVICS------------------------EFMSLRLTSEASREACAGRL 839 Query: 898 EVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 957 EV Y G+WGTV VVCRQLGC + S P+ +D+V+C Sbjct: 840 EVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGP 899 Query: 958 SYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRL 1017 LW CP + W + ++P +TW+T + +RL Sbjct: 900 DTLWQCPSSPW-----------------EKRLASPSEETWITCD-----------NKIRL 931 Query: 1018 VNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 1077 G C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+ A A FGQG+GPI Sbjct: 932 QEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPI 991 Query: 1078 VLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARP 1137 L++V+C GNES LW CP + W CGH EDA V C+ + T P TT R Sbjct: 992 WLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKT------PQKATTGRS 1045 Query: 1138 S 1138 S Sbjct: 1046 S 1046 Score = 766 bits (1979), Expect = 0.0 Identities = 415/1023 (40%), Positives = 543/1023 (53%), Gaps = 158/1023 (15%) Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161 LRLV+G+ +C GRVE+ + WGTVC++ W +V+C QLGC A+ APG A GS Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110 Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220 G I +D V C G+ES LW C H+GW H NC H +DAGV CS Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152 Query: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280 S+L +RL GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A Sbjct: 153 -------DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205 Query: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340 +S G++ FG+GSGPI DD+ C+G+ES LW+C H GW HNC H+EDAGVICS Sbjct: 206 VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259 Query: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400 + L+LRLV+G C GR+EV ++G WGT+CDD WD+ DA V Sbjct: 260 ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303 Query: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460 C+QLGC A +A G +G G I LD V C G+E +W C H+ W H C H+EDAGV Sbjct: 304 CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363 Query: 461 ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 520 CS S L LRL GG RC G VEV + G VCD Sbjct: 364 TCS------------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399 Query: 521 DSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS 580 W +A+VVCRQLGCG A+ + L C+GNE+ LW C + W Sbjct: 400 RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459 Query: 581 HNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVE 640 C H E+A + CSA + RLV G C GRVE Sbjct: 460 LTCDHYEEAKITCSAHR---------------------------EPRLVGGDIPCSGRVE 492 Query: 641 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHES 700 V + +WG++CD + A+V+CR+L CG S G A FG+G+G I ++ +C GHES Sbjct: 493 VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552 Query: 701 YLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNG 760 +L CP C H D GV+C SR T +RLVNG Sbjct: 553 HLSLCPVAPRPEGTCSHSRDVGVVC----SRYT--------------------EIRLVNG 588 Query: 761 GDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 820 C+GRVE+ G+WG++C+ WD DA+V+C+QL CG A+S PG ARFG+G+G I Sbjct: 589 KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRH 648 Query: 821 DVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT---WPTSRASTAG 877 C+G E ++ CP + C + A VICS +QS+ S ++ PT T Sbjct: 649 MFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPT--RPTIP 706 Query: 878 SESTLA------LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAM 931 ES +A LRLVNGG RC GRVE+ ++GSWGT+CDD WD +DA+VVCRQLGCG A+ Sbjct: 707 EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766 Query: 932 SAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 991 +A G+A FG+G+GPI LD+++C+G ES +W C +GW NC H EDAGVICS S Sbjct: 767 NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS--- 823 Query: 992 PRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANV 1051 L + SE+S + C GR+EV Y G+WGTV S V Sbjct: 824 -------------LRLTSEAS--------REACAGRLEVFYNGAWGTVGKSSMSETTVGV 862 Query: 1052 VCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAG 1111 VCRQLGC + S P+ +D+V+C LW CP W E+ Sbjct: 863 VCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETW 922 Query: 1112 VIC 1114 + C Sbjct: 923 ITC 925 Score = 626 bits (1614), Expect = e-179 Identities = 359/915 (39%), Positives = 466/915 (50%), Gaps = 145/915 (15%) Query: 472 SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 526 SP T+ T+ L S SSL LRLV+G ++C GRVEV + WGTVC++ W Sbjct: 25 SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83 Query: 527 DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGH 585 +V+C QLGC A+ APG A GSG I +D V C GNES LW C H+GW H NC H Sbjct: 84 AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143 Query: 586 SEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRG 645 +DAGV CS S+L +RL GG+ C GR+E+ ++G Sbjct: 144 QQDAGVTCS-------------------------DGSNLEMRLTRGGNMCSGRIEIKFQG 178 Query: 646 SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 705 WGTVCDD+++ + A+V+CRQL CG A S G++ FG+GSGPI DD+ C+G+ES LW+C Sbjct: 179 RWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNC 238 Query: 706 PNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQ 765 + GW HNC H EDAGVICS + L+LRLV+G C Sbjct: 239 KHQGWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECS 276 Query: 766 GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 825 GR+EV +QG WGT+CDD WD+ DA V C+QLGC A++A G +G G I LD V C Sbjct: 277 GRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQ 336 Query: 826 GHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALR 885 GHE +W C H+ W H C H+EDAGV CS S L LR Sbjct: 337 GHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELR 374 Query: 886 LVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGP 945 L GG RC G VEV Q G VCD W +A+VVCRQLGCG A+ + Sbjct: 375 LRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATN 434 Query: 946 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL 1005 L C+G+E+ LW C + W C H+E+A + CSA + Sbjct: 435 TWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP---------------- 478 Query: 1006 TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 1065 RLV G C GRVEV + +WG++CD + A+V+CR+L CG +S Sbjct: 479 ----------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSIL 528 Query: 1066 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ----INS 1121 G A FG+G+G I ++ +C G+ES+L CP C H D GV+CS +N Sbjct: 529 GGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNG 588 Query: 1122 TTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINL 1181 T T S C KC + G R Sbjct: 589 KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLC--------QQLKCGVALSTPGGARFGK 640 Query: 1182 GFSNLKLEAHHNCSFDYVEIFD---GSLNSSL-----LLGKICNDTRQIFTSSYN----- 1228 G + H C+ + D +L +SL + IC+ + SS N Sbjct: 641 GNGQIWRHMFH-CTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLG 699 Query: 1229 --RMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVC 1286 R TI S ++ +G LRLVN G CAGRVEIYH G+WGT+C Sbjct: 700 PTRPTIPEESAVACIESG------------QLRLVN---GGGRCAGRVEIYHEGSWGTIC 744 Query: 1287 DDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWF 1346 DDSW + +A VVCRQLGCG A++A G+A+FG G+GPI LD+++C+G ES +WQC + GW Sbjct: 745 DDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWG 804 Query: 1347 SHNCNHREDAGVICS 1361 NC H+EDAGVICS Sbjct: 805 QQNCRHKEDAGVICS 819 Score = 617 bits (1590), Expect = e-176 Identities = 366/1024 (35%), Positives = 497/1024 (48%), Gaps = 175/1024 (17%) Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422 LRLV+G ++C GRVEV + WGTVC++ W +V+C QLGC A APG A GS Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110 Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481 G I +D V C G ES LW C H+GW H NC H +DAGV CS Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154 Query: 482 PASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541 S+L +RL GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A+ Sbjct: 155 --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206 Query: 542 LAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPT 601 G++ FG+GSGPI DD+ C+GNES LW+C H GW HNC H+EDAGVICS Sbjct: 207 SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------- 259 Query: 602 PIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 661 KG + L+LRLV+G C GR+EV ++G WGT+CDD WD+ DA Sbjct: 260 ----------------KGAD--LSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAA 301 Query: 662 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDA 721 V C+QLGC A +A G +G G I LD V C GHE +W C ++ W H C H+EDA Sbjct: 302 VACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDA 361 Query: 722 GVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 781 GV CS S L LRL GG RC G VEV Q G VCD Sbjct: 362 GVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399 Query: 782 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 841 W +A+VVCRQLGCG A+ + L C+G+E+ LW C + W Sbjct: 400 RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459 Query: 842 HNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLY 901 C H E+A + CSA + RLV G C GRVEV + Sbjct: 460 LTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKH 495 Query: 902 QGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLW 961 +WG++CD + A+V+CR+L CG +S G A FG+G+G I ++ +C GHES+L Sbjct: 496 GDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLS 555 Query: 962 SCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGG 1021 CP C H D GV+CS +RLVNG Sbjct: 556 LCPVAPRPEGTCSHSRDVGVVCSRYTE--------------------------IRLVNGK 589 Query: 1022 DRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD 1081 C GRVE+ G+WG++C+ WD DA+V+C+QL CG A+S PG ARFG+G+G I Sbjct: 590 TPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHM 649 Query: 1082 VRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ---INSTTTDWWHPTTTTTARPS 1138 C+G E ++ CP C + A VICS Q ++S + PT T S Sbjct: 650 FHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEES 709 Query: 1139 S----------------NCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINL 1181 + C G + Y G++ + ++ ++A V ++ G IN Sbjct: 710 AVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR-QLGCGEAINA 768 Query: 1182 GFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRS 1236 S AH G + L ++ CN Q + + + + Sbjct: 769 TGS-----AHF-----------GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKE 812 Query: 1237 DISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAE 1296 D + F++ LRL + +S CAGR+E+++ G WGTV S + Sbjct: 813 DAGVICSEFMS----------LRLTS-EASREACAGRLEVFYNGAWGTVGKSSMSETTVG 861 Query: 1297 VVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDA 1356 VVCRQLGC + + S P+ +D+V+C TLWQC + W + E+ Sbjct: 862 VVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEET 921 Query: 1357 GVIC 1360 + C Sbjct: 922 WITC 925 Score = 130 bits (328), Expect = 9e-30 Identities = 54/92 (58%), Positives = 69/92 (75%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329 C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A A FG G+GPI L++V+ Sbjct: 938 CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 C G ES+LW C R W C H+EDA V C+ Sbjct: 998 CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029 Score = 86.3 bits (212), Expect = 2e-16 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%) Query: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1317 +RLVN + C GRVE+ G WG++C+ W I++A V+C+QL CG A+S G A FG Sbjct: 583 IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639 Query: 1318 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1367 G+G I C+GTE + C + C + A VICSGN T Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689 Score = 82.0 bits (201), Expect = 5e-15 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%) Query: 1254 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1313 SD LRL S CAG VE+ G VCD W ++EA+VVCRQLGCG A+ Sbjct: 369 SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425 Query: 1314 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1363 Y + L C+G E++LW C+N W C+H E+A + CS + Sbjct: 426 VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475 >gi|44662834 CD163 antigen isoform a [Homo sapiens] Length = 1156 Score = 783 bits (2023), Expect = 0.0 Identities = 442/1141 (38%), Positives = 588/1141 (51%), Gaps = 182/1141 (15%) Query: 14 WGQVLSTGGWIPRTTDYASLIPSEVPLDTTV-----AEGSPFPSELTLESTVAEGSPISL 68 WG V + G W + + S+I +++ T + A S + ++ G+ +L Sbjct: 72 WGTVCNNG-W---SMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESAL 127 Query: 69 ESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCD 128 + S + T ++GS+ L +RL G C GR+EI ++G WGTVCD Sbjct: 128 WDCKHDGWGKHSNCTHQQDAGVTCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCD 185 Query: 129 DSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLS 188 D+++ + A+V+CRQL CG A+S G++ FG+GSGPI DD+ C+G+ES LW+C H GW Sbjct: 186 DNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGK 245 Query: 189 HNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVE 248 HNC H EDAGVICS + L+LRLV+G C GR+E Sbjct: 246 HNCDHAEDAGVICSKG-------------------------ADLSLRLVDGVTECSGRLE 280 Query: 249 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 308 V ++G WGT+CDD WD+ DA V C+QLGC A++A G +G G I LD V C GHE Sbjct: 281 VRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEP 340 Query: 309 YLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 368 +W C H+ W H C H+EDAGV CS S L LRL G Sbjct: 341 AVWQCKHHEWGKHYCNHNEDAGVTCS----------------------DGSDLELRLRGG 378 Query: 369 GDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIV 426 G RC G VEV + G VCD W +A+VVCRQLGCG A TS ++ + + Sbjct: 379 GSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLF 438 Query: 427 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTV 486 L C+G E+ LW C + W C H E+A + CSA Sbjct: 439 LSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------- 477 Query: 487 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 546 RLV G C GRVEV + +WG++CD + A+V+CR+L CG + G Sbjct: 478 -------PRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGG 530 Query: 547 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPR 606 A FG+G+G I ++ +C G+ES+L CP C HS D GV+CS Sbjct: 531 AHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYT--------- 581 Query: 607 SWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 666 +RLVNG C+GRVE+ G+WG++C+ WD DA+V+C+Q Sbjct: 582 ------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQ 623 Query: 667 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726 L CG A S PG ARFG+G+G I C+G E ++ CP + C + A VICS Sbjct: 624 LKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS 683 Query: 727 AAQSR------STPRPDTWPT-SHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTV 779 QS+ S+ T PT S S LRLVNGG RC GRVE+ ++GSWGT+ Sbjct: 684 GNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTI 743 Query: 780 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGW 839 CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G ES +W C +GW Sbjct: 744 CDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGW 803 Query: 840 LSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR--CRGRV 897 NC H EDAGVICS ++LRL + R C GR+ Sbjct: 804 GQQNCRHKEDAGVICS------------------------EFMSLRLTSEASREACAGRL 839 Query: 898 EVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 957 EV Y G+WGTV VVCRQLGC + S P+ +D+V+C Sbjct: 840 EVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGP 899 Query: 958 SYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRL 1017 LW CP + W + ++P +TW+T + +RL Sbjct: 900 DTLWQCPSSPW-----------------EKRLASPSEETWITCD-----------NKIRL 931 Query: 1018 VNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 1077 G C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+ A A FGQG+GPI Sbjct: 932 QEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPI 991 Query: 1078 VLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARP 1137 L++V+C GNES LW CP + W CGH EDA V C+ + T P TT R Sbjct: 992 WLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKT------PQKATTGRS 1045 Query: 1138 S 1138 S Sbjct: 1046 S 1046 Score = 766 bits (1979), Expect = 0.0 Identities = 415/1023 (40%), Positives = 543/1023 (53%), Gaps = 158/1023 (15%) Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161 LRLV+G+ +C GRVE+ + WGTVC++ W +V+C QLGC A+ APG A GS Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110 Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220 G I +D V C G+ES LW C H+GW H NC H +DAGV CS Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152 Query: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280 S+L +RL GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A Sbjct: 153 -------DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205 Query: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340 +S G++ FG+GSGPI DD+ C+G+ES LW+C H GW HNC H+EDAGVICS Sbjct: 206 VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259 Query: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400 + L+LRLV+G C GR+EV ++G WGT+CDD WD+ DA V Sbjct: 260 ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303 Query: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460 C+QLGC A +A G +G G I LD V C G+E +W C H+ W H C H+EDAGV Sbjct: 304 CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363 Query: 461 ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 520 CS S L LRL GG RC G VEV + G VCD Sbjct: 364 TCS------------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399 Query: 521 DSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS 580 W +A+VVCRQLGCG A+ + L C+GNE+ LW C + W Sbjct: 400 RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459 Query: 581 HNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVE 640 C H E+A + CSA + RLV G C GRVE Sbjct: 460 LTCDHYEEAKITCSAHR---------------------------EPRLVGGDIPCSGRVE 492 Query: 641 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHES 700 V + +WG++CD + A+V+CR+L CG S G A FG+G+G I ++ +C GHES Sbjct: 493 VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552 Query: 701 YLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNG 760 +L CP C H D GV+C SR T +RLVNG Sbjct: 553 HLSLCPVAPRPEGTCSHSRDVGVVC----SRYT--------------------EIRLVNG 588 Query: 761 GDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 820 C+GRVE+ G+WG++C+ WD DA+V+C+QL CG A+S PG ARFG+G+G I Sbjct: 589 KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRH 648 Query: 821 DVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT---WPTSRASTAG 877 C+G E ++ CP + C + A VICS +QS+ S ++ PT T Sbjct: 649 MFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPT--RPTIP 706 Query: 878 SESTLA------LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAM 931 ES +A LRLVNGG RC GRVE+ ++GSWGT+CDD WD +DA+VVCRQLGCG A+ Sbjct: 707 EESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAI 766 Query: 932 SAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 991 +A G+A FG+G+GPI LD+++C+G ES +W C +GW NC H EDAGVICS S Sbjct: 767 NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS--- 823 Query: 992 PRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANV 1051 L + SE+S + C GR+EV Y G+WGTV S V Sbjct: 824 -------------LRLTSEAS--------REACAGRLEVFYNGAWGTVGKSSMSETTVGV 862 Query: 1052 VCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAG 1111 VCRQLGC + S P+ +D+V+C LW CP W E+ Sbjct: 863 VCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETW 922 Query: 1112 VIC 1114 + C Sbjct: 923 ITC 925 Score = 626 bits (1614), Expect = e-179 Identities = 359/915 (39%), Positives = 466/915 (50%), Gaps = 145/915 (15%) Query: 472 SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 526 SP T+ T+ L S SSL LRLV+G ++C GRVEV + WGTVC++ W Sbjct: 25 SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83 Query: 527 DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGH 585 +V+C QLGC A+ APG A GSG I +D V C GNES LW C H+GW H NC H Sbjct: 84 AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143 Query: 586 SEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRG 645 +DAGV CS S+L +RL GG+ C GR+E+ ++G Sbjct: 144 QQDAGVTCS-------------------------DGSNLEMRLTRGGNMCSGRIEIKFQG 178 Query: 646 SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 705 WGTVCDD+++ + A+V+CRQL CG A S G++ FG+GSGPI DD+ C+G+ES LW+C Sbjct: 179 RWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNC 238 Query: 706 PNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQ 765 + GW HNC H EDAGVICS + L+LRLV+G C Sbjct: 239 KHQGWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECS 276 Query: 766 GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 825 GR+EV +QG WGT+CDD WD+ DA V C+QLGC A++A G +G G I LD V C Sbjct: 277 GRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQ 336 Query: 826 GHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALR 885 GHE +W C H+ W H C H+EDAGV CS S L LR Sbjct: 337 GHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELR 374 Query: 886 LVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGP 945 L GG RC G VEV Q G VCD W +A+VVCRQLGCG A+ + Sbjct: 375 LRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATN 434 Query: 946 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPAL 1005 L C+G+E+ LW C + W C H+E+A + CSA + Sbjct: 435 TWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP---------------- 478 Query: 1006 TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 1065 RLV G C GRVEV + +WG++CD + A+V+CR+L CG +S Sbjct: 479 ----------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSIL 528 Query: 1066 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ----INS 1121 G A FG+G+G I ++ +C G+ES+L CP C H D GV+CS +N Sbjct: 529 GGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNG 588 Query: 1122 TTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINL 1181 T T S C KC + G R Sbjct: 589 KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLC--------QQLKCGVALSTPGGARFGK 640 Query: 1182 GFSNLKLEAHHNCSFDYVEIFD---GSLNSSL-----LLGKICNDTRQIFTSSYN----- 1228 G + H C+ + D +L +SL + IC+ + SS N Sbjct: 641 GNGQIWRHMFH-CTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLG 699 Query: 1229 --RMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVC 1286 R TI S ++ +G LRLVN G CAGRVEIYH G+WGT+C Sbjct: 700 PTRPTIPEESAVACIESG------------QLRLVN---GGGRCAGRVEIYHEGSWGTIC 744 Query: 1287 DDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWF 1346 DDSW + +A VVCRQLGCG A++A G+A+FG G+GPI LD+++C+G ES +WQC + GW Sbjct: 745 DDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWG 804 Query: 1347 SHNCNHREDAGVICS 1361 NC H+EDAGVICS Sbjct: 805 QQNCRHKEDAGVICS 819 Score = 617 bits (1590), Expect = e-176 Identities = 366/1024 (35%), Positives = 497/1024 (48%), Gaps = 175/1024 (17%) Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422 LRLV+G ++C GRVEV + WGTVC++ W +V+C QLGC A APG A GS Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110 Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481 G I +D V C G ES LW C H+GW H NC H +DAGV CS Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154 Query: 482 PASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541 S+L +RL GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A+ Sbjct: 155 --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206 Query: 542 LAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPT 601 G++ FG+GSGPI DD+ C+GNES LW+C H GW HNC H+EDAGVICS Sbjct: 207 SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------- 259 Query: 602 PIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 661 KG + L+LRLV+G C GR+EV ++G WGT+CDD WD+ DA Sbjct: 260 ----------------KGAD--LSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAA 301 Query: 662 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDA 721 V C+QLGC A +A G +G G I LD V C GHE +W C ++ W H C H+EDA Sbjct: 302 VACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDA 361 Query: 722 GVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 781 GV CS S L LRL GG RC G VEV Q G VCD Sbjct: 362 GVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399 Query: 782 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 841 W +A+VVCRQLGCG A+ + L C+G+E+ LW C + W Sbjct: 400 RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459 Query: 842 HNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLY 901 C H E+A + CSA + RLV G C GRVEV + Sbjct: 460 LTCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKH 495 Query: 902 QGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLW 961 +WG++CD + A+V+CR+L CG +S G A FG+G+G I ++ +C GHES+L Sbjct: 496 GDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLS 555 Query: 962 SCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGG 1021 CP C H D GV+CS +RLVNG Sbjct: 556 LCPVAPRPEGTCSHSRDVGVVCSRYTE--------------------------IRLVNGK 589 Query: 1022 DRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD 1081 C GRVE+ G+WG++C+ WD DA+V+C+QL CG A+S PG ARFG+G+G I Sbjct: 590 TPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHM 649 Query: 1082 VRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ---INSTTTDWWHPTTTTTARPS 1138 C+G E ++ CP C + A VICS Q ++S + PT T S Sbjct: 650 FHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEES 709 Query: 1139 S----------------NCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINL 1181 + C G + Y G++ + ++ ++A V ++ G IN Sbjct: 710 AVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR-QLGCGEAINA 768 Query: 1182 GFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRS 1236 S AH G + L ++ CN Q + + + + Sbjct: 769 TGS-----AHF-----------GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKE 812 Query: 1237 DISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAE 1296 D + F++ LRL + +S CAGR+E+++ G WGTV S + Sbjct: 813 DAGVICSEFMS----------LRLTS-EASREACAGRLEVFYNGAWGTVGKSSMSETTVG 861 Query: 1297 VVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDA 1356 VVCRQLGC + + S P+ +D+V+C TLWQC + W + E+ Sbjct: 862 VVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEET 921 Query: 1357 GVIC 1360 + C Sbjct: 922 WITC 925 Score = 130 bits (328), Expect = 9e-30 Identities = 54/92 (58%), Positives = 69/92 (75%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329 C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A A FG G+GPI L++V+ Sbjct: 938 CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 C G ES+LW C R W C H+EDA V C+ Sbjct: 998 CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029 Score = 86.3 bits (212), Expect = 2e-16 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%) Query: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1317 +RLVN + C GRVE+ G WG++C+ W I++A V+C+QL CG A+S G A FG Sbjct: 583 IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639 Query: 1318 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1367 G+G I C+GTE + C + C + A VICSGN T Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689 Score = 82.0 bits (201), Expect = 5e-15 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%) Query: 1254 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1313 SD LRL S CAG VE+ G VCD W ++EA+VVCRQLGCG A+ Sbjct: 369 SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425 Query: 1314 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1363 Y + L C+G E++LW C+N W C+H E+A + CS + Sbjct: 426 VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475 >gi|18152779 scavenger receptor cysteine rich domain containing, group B (4 domains) [Homo sapiens] Length = 575 Score = 512 bits (1319), Expect = e-144 Identities = 263/535 (49%), Positives = 316/535 (59%), Gaps = 34/535 (6%) Query: 609 PSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 668 P + ALQ P L RLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLG Sbjct: 43 PLASALQPTPLPFQEL--RLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLG 100 Query: 669 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAA 728 CG A P FGQG GPI+LD+V C G E+ L C + GW HNC H+ED V+C Sbjct: 101 CGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEF 160 Query: 729 QSRSTPRPDTWPTSHASTA--GSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 786 P + T +S ++RLV G + CQGRVE+L+ G WGTVCDD W Sbjct: 161 LPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGL 220 Query: 787 NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 846 DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW HNCGH Sbjct: 221 PDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGH 280 Query: 847 SEDAGVIC--------------------------SASQSRPTPSPDTWPTSRASTAGSES 880 EDAG +C SA+ P PS +T + A+ A + Sbjct: 281 HEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKK 340 Query: 881 TLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 940 + LRLV G CRGRVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG Sbjct: 341 SGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFG 400 Query: 941 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP-RPDTWLT 999 G GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ + + D T Sbjct: 401 YGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSET 460 Query: 1000 TNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 1059 T +P LRLVNG RC GRVE+ WGTVCDD+WD A V+CRQLGCG Sbjct: 461 TRVP---TPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCG 517 Query: 1060 WAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 1114 A++APG A FG G GPI+LD+V+C G ES L C H W HNC H EDA V+C Sbjct: 518 QALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572 Score = 512 bits (1319), Expect = e-144 Identities = 258/519 (49%), Positives = 312/519 (60%), Gaps = 25/519 (4%) Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422 LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A P FGQG Sbjct: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117 Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLP 482 GPI+LD+V C G E+ L C GW HNC H ED V+C P+ L + P Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177 Query: 483 ASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAML 542 + +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG AM Sbjct: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237 Query: 543 APGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS-----ALQ 597 A NA FG G+G I+LD+V C G E L +C GW HNCGH EDAG +C+ L Sbjct: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297 Query: 598 WLPTPIRPRSW-----PSSHALQTCKGPESSL-------------ALRLVNGGDRCQGRV 639 LP+ W PS+ + E++L LRLV G C+GRV Sbjct: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357 Query: 640 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 699 EVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G GP++LD+V C+G E Sbjct: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417 Query: 700 SYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP-RPDTWPTSHASTAGSESSLALRLV 758 + L C + GW HNCGHHEDAG +C+ + + D T+ T LRLV Sbjct: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476 Query: 759 NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 818 NG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A++APG A FG G GPI+ Sbjct: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536 Query: 819 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 857 LD+V+C G ES L C H W +HNC HSEDA V+C S Sbjct: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575 Score = 507 bits (1305), Expect = e-143 Identities = 261/540 (48%), Positives = 315/540 (58%), Gaps = 35/540 (6%) Query: 81 LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140 L+P S L+ T + LRLV G RC+GR+E+++ GSWG+VCDD WD DANVVC Sbjct: 41 LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96 Query: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200 RQLGCG A+ P FGQG GPI LD+V C G E+ L C GW HNC H ED V+ Sbjct: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156 Query: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260 C P + R +PP +S ++RLV G + C+GRVE+L+ G WGTVCD Sbjct: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215 Query: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320 D W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW Sbjct: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275 Query: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354 HNCGH EDAG +C SA P PS +T + A+ Sbjct: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335 Query: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414 A + S LRLV G C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A A G Sbjct: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395 Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTP-SP 473 FG G GP++LD+V C+G E+ L C H GW HNC H EDAG +C+ Sbjct: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQ 455 Query: 474 DTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 533 D T +P LRLVNG RC+GRVE+ WGTVCDD+WD A V+CR Sbjct: 456 DGSETTRVPTPRPRDGH---LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCR 512 Query: 534 QLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVIC 593 QLGCG A+ APG A FG G GPI+LD+V+C G ES L C H W +HNC HSEDA V+C Sbjct: 513 QLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572 Score = 388 bits (997), Expect = e-107 Identities = 199/392 (50%), Positives = 238/392 (60%), Gaps = 30/392 (7%) Query: 755 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 814 LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG Sbjct: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117 Query: 815 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT-WPTSRA 873 GPI+LD+V C G E+ L C GW HNC H ED V+C + PT P TSRA Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCD--EFLPTQPPTRKMLTSRA 175 Query: 874 ---STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 930 + +S ++RLV G + C+GRVE+L+ G WGTVCDD W DA VVCRQLGCG A Sbjct: 176 PPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAA 235 Query: 931 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA----- 985 M+A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C+ Sbjct: 236 MAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPT 295 Query: 986 --AQSQSTPRPDTWLTTNLPALTVGSESSLA-----------------LRLVNGGDRCRG 1026 A S R D T+ A VG + S LRLV G CRG Sbjct: 296 LTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRG 355 Query: 1027 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1086 RVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G GP++LD+V C+G Sbjct: 356 RVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAG 415 Query: 1087 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1118 E+ L C H GW HNCGHHEDAG +C+ + Sbjct: 416 TEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447 Score = 270 bits (690), Expect = 9e-72 Identities = 134/261 (51%), Positives = 163/261 (62%), Gaps = 11/261 (4%) Query: 884 LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 943 LRLV G RCRGR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG Sbjct: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117 Query: 944 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLP 1003 GPI+LD+V C G E+ L C GW HNC H+ED V+C P LT+ P Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM-LTSRAP 176 Query: 1004 ALTV-GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1062 T+ +S ++RLV G + C+GRVE+L+ G WGTVCDD W DA VVCRQLGCG AM Sbjct: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236 Query: 1063 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC-------- 1114 +A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C Sbjct: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296 Query: 1115 SATQINSTTTDW-WHPTTTTT 1134 +A ++T DW W + T Sbjct: 297 TALPSSATREDWAWQTDPSAT 317 Score = 132 bits (332), Expect = 3e-30 Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%) Query: 1254 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1313 S+ ++RLV LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A N Sbjct: 185 SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241 Query: 1314 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1362 A+FG G+G I LD+V C G E L C++ GW HNC H EDAG +C+G Sbjct: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290 Score = 129 bits (325), Expect = 2e-29 Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%) Query: 1253 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1312 P D LRLVN C GRVE+Y G WGTVCDD+W ++ A V+CRQLGCG+A++A G Sbjct: 468 PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524 Query: 1313 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360 A+FG G GPI LD+V+C G ES L C + W +HNC+H EDA V+C Sbjct: 525 EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572 Score = 126 bits (317), Expect = 2e-28 Identities = 52/95 (54%), Positives = 64/95 (67%) Query: 1268 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1327 G C GRVE+ H G WGTVCDD W +A V CR+ GCG A+ A G +FG G GP+ LD+ Sbjct: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410 Query: 1328 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1362 V C+GTE+ L C + GW HNC H EDAG +C+G Sbjct: 411 VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445 Score = 121 bits (304), Expect = 5e-27 Identities = 51/91 (56%), Positives = 63/91 (69%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329 C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+ FG G GPI LD+VE Sbjct: 67 CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360 C G E+ L +C +RGW HNC H ED V+C Sbjct: 127 CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157 >gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] Length = 343 Score = 494 bits (1271), Expect = e-139 Identities = 230/252 (91%), Positives = 233/252 (92%), Gaps = 2/252 (0%) Query: 484 STVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 543 S VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA Sbjct: 8 SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67 Query: 544 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPI 603 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS TPI Sbjct: 68 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGP-PRTPI 126 Query: 604 RPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 663 RPRSWPS GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV Sbjct: 127 RPRSWPSRFLCSPI-GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 185 Query: 664 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGV 723 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGV Sbjct: 186 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGV 245 Query: 724 ICSAAQSRSTPR 735 ICS + + + PR Sbjct: 246 ICSGSWAVAGPR 257 Score = 468 bits (1203), Expect = e-131 Identities = 213/250 (85%), Positives = 225/250 (90%), Gaps = 1/250 (0%) Query: 745 STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 804 S GSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAM A Sbjct: 8 SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67 Query: 805 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS 864 PGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGHSEDAGVICS R Sbjct: 68 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127 Query: 865 PDTWPTS-RASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCR 923 P +WP+ S G ES+LALRLVNGGDRC+GRVEVLY+GSWGTVCDD WDTNDANVVCR Sbjct: 128 PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187 Query: 924 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 983 QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHEDAGVIC Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247 Query: 984 SAAQSQSTPR 993 S + + + PR Sbjct: 248 SGSWAVAGPR 257 Score = 466 bits (1198), Expect = e-130 Identities = 225/291 (77%), Positives = 237/291 (81%), Gaps = 25/291 (8%) Query: 619 GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 678 G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA APGN Sbjct: 11 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 70 Query: 679 ARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 738 ARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNCGH EDAGVICS R+ RP + Sbjct: 71 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRS 130 Query: 739 WPTSH-ASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLG 797 WP+ S G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCRQLG Sbjct: 131 WPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 190 Query: 798 CGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 857 CGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGH EDAGVICS S Sbjct: 191 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250 Query: 858 QS-----RPTPSP-----------------DTWPTSRA--STAGSESTLAL 884 + RP P DT PT A + AGS +T+A+ Sbjct: 251 WAVAGPRRPQEMPGLARAQDPLFWMMCAAQDTSPTCGAAPTMAGSPTTVAI 301 Score = 457 bits (1175), Expect = e-128 Identities = 214/257 (83%), Positives = 223/257 (86%), Gaps = 1/257 (0%) Query: 353 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412 S GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT+DANVVCRQLGCGWA A Sbjct: 8 SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67 Query: 413 PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472 PGNARFGQGSGPIVLDDVRCSG ESYLWSCPHNGWLSHNC HSEDAGVICS + Sbjct: 68 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127 Query: 473 PDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 532 P + P+ L S +G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC Sbjct: 128 PRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 186 Query: 533 RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVI 592 RQLGCGWA APGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNCGH EDAGVI Sbjct: 187 RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 246 Query: 593 CSALQWLPTPIRPRSWP 609 CS + P RP+ P Sbjct: 247 CSGSWAVAGPRRPQEMP 263 Score = 457 bits (1175), Expect = e-128 Identities = 218/294 (74%), Positives = 236/294 (80%), Gaps = 28/294 (9%) Query: 95 GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154 GS+S LALRLVNG RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM APGN Sbjct: 11 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 70 Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214 A FGQGSGPI LDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS P++ +RP S Sbjct: 71 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRS 130 Query: 215 WPVR-ISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCR 273 WP R + P+ G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDTNDANVVCR Sbjct: 131 WPSRFLCSPI---GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187 Query: 274 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVIC 333 QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP+NGWL+HNCGH EDAGVIC Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247 Query: 334 SA---------PQSRP-------------TPSPDTWPTSHA--STAGSESSLAL 363 S PQ P + DT PT A + AGS +++A+ Sbjct: 248 SGSWAVAGPRRPQEMPGLARAQDPLFWMMCAAQDTSPTCGAAPTMAGSPTTVAI 301 Score = 454 bits (1169), Expect = e-127 Identities = 206/244 (84%), Positives = 221/244 (90%), Gaps = 1/244 (0%) Query: 874 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 933 S GSES+LALRLVNGGDRC+GRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWAM A Sbjct: 8 SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67 Query: 934 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 993 PGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS ++ R Sbjct: 68 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127 Query: 994 PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVC 1053 P +W + L +G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDDSWDTNDANVVC Sbjct: 128 PRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 186 Query: 1054 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVI 1113 RQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+ GWL+HNCGHHEDAGVI Sbjct: 187 RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 246 Query: 1114 CSAT 1117 CS + Sbjct: 247 CSGS 250 Score = 156 bits (394), Expect = 2e-37 Identities = 73/110 (66%), Positives = 78/110 (70%), Gaps = 3/110 (2%) Query: 1254 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1313 S LRLVN C GRVE+ + G+WGTVCDDSW +A VVCRQLGCG A SA GN Sbjct: 144 SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 200 Query: 1314 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1363 A FG GSGPI LDDV CSG ES LW C N GW SHNC H EDAGVICSG+ Sbjct: 201 ARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250 Score = 155 bits (393), Expect = 3e-37 Identities = 85/153 (55%), Positives = 92/153 (60%), Gaps = 11/153 (7%) Query: 1244 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLG 1303 GFL S LRLVN C GRVE+ + G+WGTVCDDSW +A VVCRQLG Sbjct: 4 GFLFSPVGSESSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 60 Query: 1304 CGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1363 CG A+ A GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG Sbjct: 61 CGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGG 120 Query: 1364 HLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSS 1396 TP RP + S FL P G SS Sbjct: 121 PPRTP------IRPRSWPS--RFLCSPIGPESS 145 >gi|222352122 hypothetical protein LOC284297 [Homo sapiens] Length = 1573 Score = 481 bits (1237), Expect = e-135 Identities = 256/589 (43%), Positives = 318/589 (53%), Gaps = 108/589 (18%) Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161 LRL +G C GR+E+ + G WGTVCDD WD DA V CRQLGCG A++APG A+FG+G+ Sbjct: 20 LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79 Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES------- 214 GP+ L ++ C G+E L C H GW +H C H EDAGV+C A Q + R +S Sbjct: 80 GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC-AGQRVANSRDDSTSPLDGA 138 Query: 215 -WP---VRISP------------------------------------PVPTEGSESSLAL 234 WP + +SP P+ T G+ L Sbjct: 139 PWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERL 198 Query: 235 RLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSG 294 RLV+G RC GR+EV + G WGTVCDD WD DA V CR+LGCG A++APG A+FG G+G Sbjct: 199 RLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAG 258 Query: 295 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST 354 P+ +DDV C G E L CP + W NC HSEDAG++C+ P R Sbjct: 259 PVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR--------------- 303 Query: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414 LRL +G C GR+EV + G WG+VCDD+WD DA V CR+LGCG A +APG Sbjct: 304 --------LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPG 355 Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPD 474 A FG+GSGPI+LDD+RC G E+ L CP W H+C H EDAG +C P Sbjct: 356 GAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYV--PP 413 Query: 475 TLPT----------ITLPASTVGSES------------------------SLALRLVNGG 500 T PT + P ST+ S++ S LRLV G Sbjct: 414 TAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGP 473 Query: 501 DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA-PGNARFGQGSGPIVLD 559 +C GR+EV + WGTVCDDSWD D+ VVCR+LGCG P RFG G+GPI LD Sbjct: 474 SKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLD 533 Query: 560 DVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSW 608 DV C G E+ L CP W HNC H+ED GV C+ L + P SW Sbjct: 534 DVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSW 582 Score = 480 bits (1235), Expect = e-135 Identities = 255/600 (42%), Positives = 312/600 (52%), Gaps = 109/600 (18%) Query: 352 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411 A+ G ++ LRL +G C GR+EV + G WGTVCDD WD DA V CRQLGCG A + Sbjct: 9 AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68 Query: 412 APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSA------- 464 APG A FG+G+GP+ L ++ C G E L C H GW +H C H EDAGV+C+ Sbjct: 69 APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128 Query: 465 ----------------------------------------AHSWSTPSPDTLPTITLPAS 484 A +P P + P Sbjct: 129 DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188 Query: 485 TVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAP 544 T G+ LRLV+G RC GR+EV + G WGTVCDD WD DA V CR+LGCG A+ AP Sbjct: 189 TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248 Query: 545 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIR 604 G ARFG G+GP+ +DDV C G E L CP + W NC HSEDAG++C+ P P Sbjct: 249 GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG----PAP-- 302 Query: 605 PRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 664 LRL +G C GR+EV + G WG+VCDD+WD DA V C Sbjct: 303 --------------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVAC 342 Query: 665 RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 724 R+LGCG A +APG A FG+GSGPI+LDD+RC G+E+ L CP W H+C H EDAG + Sbjct: 343 RELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAV 402 Query: 725 CSAA------------QSRSTPR------PDTWPTSHASTAG----------------SE 750 C + STPR P T + TAG Sbjct: 403 CDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEA 462 Query: 751 SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA-PGNAR 809 S LRLV G +C GR+EV + WGTVCDDSWD D+ VVCR+LGCG P R Sbjct: 463 GSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGR 522 Query: 810 FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS-PDTW 868 FG G+GPI LDDV C G E+ L CP W HNC H+ED GV C+ + S P +W Sbjct: 523 FGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSW 582 Score = 476 bits (1225), Expect = e-134 Identities = 257/599 (42%), Positives = 314/599 (52%), Gaps = 105/599 (17%) Query: 481 LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540 L A+ VG ++ LRL +G C GR+EV + G WGTVCDD WD DA V CRQLGCG A Sbjct: 7 LLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGA 66 Query: 541 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVIC------- 593 + APG A FG+G+GP+ L ++ C GNE L C H GW +H C H EDAGV+C Sbjct: 67 LAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVAN 126 Query: 594 ------SALQWLPTP---------------------------------IRPRSWPSSHAL 614 S L P P RP+ S+ A Sbjct: 127 SRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAP 186 Query: 615 QTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 674 G LRLV+G RC GR+EV + G WGTVCDD WD DA V CR+LGCG A + Sbjct: 187 LLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALA 246 Query: 675 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 734 APG ARFG G+GP+ +DDV C G E L CP + W NC H EDAG++C+ R Sbjct: 247 APGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR--- 303 Query: 735 RPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCR 794 LRL +G C GR+EV + G WG+VCDD+WD DA V CR Sbjct: 304 --------------------LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACR 343 Query: 795 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVIC 854 +LGCG A++APG A FG+GSGPI+LDD+RC G+E+ L CP W H+C H EDAG +C Sbjct: 344 ELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVC 403 Query: 855 S------ASQSRPTPSPDTWPTSRAS------------TAGSESTLA------------- 883 + PT S ++ P AS TAG A Sbjct: 404 DGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAG 463 Query: 884 ---LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA-PGNAQF 939 LRLV G +C GR+EV + WGTVCDD WD D+ VVCR+LGCG P +F Sbjct: 464 SPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRF 523 Query: 940 GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQS-QSTPRPDTW 997 G G+GPI LDDV C G E+ L CP W HNC H+ED GV C+ S P +W Sbjct: 524 GWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSW 582 Score = 476 bits (1225), Expect = e-134 Identities = 250/572 (43%), Positives = 311/572 (54%), Gaps = 105/572 (18%) Query: 626 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 685 LRL +G C GR+EV + G WGTVCDD WD DA V CRQLGCG A +APG A FG+G+ Sbjct: 20 LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79 Query: 686 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSA------------------ 727 GP+ L ++ C G+E L C + GW +H C H EDAGV+C+ Sbjct: 80 GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAP 139 Query: 728 -----------------------------AQSRSTPRPDTWPTSHAS--TAGSESSLALR 756 A + +PRP ++ A T G+ LR Sbjct: 140 WPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLR 199 Query: 757 LVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 816 LV+G RC GR+EV + G WGTVCDD WD DA V CR+LGCG A++APG ARFG G+GP Sbjct: 200 LVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGP 259 Query: 817 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTA 876 + +DDV C G E L CP + W NC HSEDAG++C+ P+P Sbjct: 260 VWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------PAP----------- 302 Query: 877 GSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 936 LRL +G C GR+EV + G WG+VCDD WD DA V CR+LGCG A++APG Sbjct: 303 ------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGG 356 Query: 937 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAA---------- 986 A FG+GSGPI+LDD+RC G+E+ L CP W H+C H EDAG +C Sbjct: 357 AFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAP 416 Query: 987 --QSQSTPR-----PDTWLTTNLPALT--------------VGSES-SLALRLVNGGDRC 1024 + STPR P + +T+ P G E+ S LRLV G +C Sbjct: 417 TDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKC 476 Query: 1025 RGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA-PGNARFGQGSGPIVLDDVR 1083 GR+EV + WGTVCDDSWD D+ VVCR+LGCG P RFG G+GPI LDDV Sbjct: 477 SGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVG 536 Query: 1084 CSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1115 C G E+ L CP W HNC H+ED GV C+ Sbjct: 537 CVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568 Score = 475 bits (1223), Expect = e-133 Identities = 257/581 (44%), Positives = 315/581 (54%), Gaps = 106/581 (18%) Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286 G ++ LRL +G C GR+EV + G WGTVCDD WD DA V CRQLGCG A++APG Sbjct: 13 GIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGG 72 Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346 A FG+G+GP+ L ++ C G+E L C H GW H C H EDAGV+C+ + + T Sbjct: 73 AFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDST 132 Query: 347 -------WP--------------TSHAS----------------------------TAGS 357 WP +HA T G+ Sbjct: 133 SPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGA 192 Query: 358 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNAR 417 LRLV+G RC GR+EV + G WGTVCDD WD DA V CR+LGCG A +APG AR Sbjct: 193 PRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGAR 252 Query: 418 FGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLP 477 FG G+GP+ +DDV C G E L CP + W NC HSEDAG++C+ P+P Sbjct: 253 FGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------PAP---- 302 Query: 478 TITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 537 LRL +G C GR+EV + G WG+VCDD+WD DA V CR+LGC Sbjct: 303 ---------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGC 347 Query: 538 GWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSA-- 595 G A+ APG A FG+GSGPI+LDD+RC GNE+ L CP W H+C H EDAG +C Sbjct: 348 GGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMP 407 Query: 596 LQWLP----------TP----IRPRSWPSSHALQTC--------------KGPES-SLAL 626 L ++P TP RP S +S A T GPE+ S L Sbjct: 408 LGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQL 467 Query: 627 RLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA-PGNARFGQGS 685 RLV G +C GR+EV + WGTVCDDSWD D+ VVCR+LGCG P RFG G+ Sbjct: 468 RLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGA 527 Query: 686 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726 GPI LDDV C G E+ L CP W HNC H+ED GV C+ Sbjct: 528 GPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568 Score = 362 bits (930), Expect = 1e-99 Identities = 197/464 (42%), Positives = 252/464 (54%), Gaps = 69/464 (14%) Query: 42 TTVAEGSPFPSELTLESTVAEGSPISLESTL-----ESTVAEGSLIPSE--STLESTVAE 94 T+ +G+P+P L LE + + P+ + ++ + S P + ST + Sbjct: 132 TSPLDGAPWPG-LLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTT 190 Query: 95 GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154 G+ LRLV+G RC GR+E+ + G WGTVCDD WD DA V CR+LGCG A++APG Sbjct: 191 GAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGG 250 Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214 A FG G+GP+ +DDV C G E L CP + W NC H EDAG++C+ P+ Sbjct: 251 ARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR------- 303 Query: 215 WPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 274 LRL +G C GR+EV + G WG+VCDD WD DA V CR+ Sbjct: 304 -------------------LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRE 344 Query: 275 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 LGCG A++APG A FG+GSGPI+LDD+RC G+E+ L CP W H+C H EDAG +C Sbjct: 345 LGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCD 404 Query: 335 ------APQSRPTPSPDTWPTSHAS------------TAG----------------SESS 360 P + PT S ++ P AS TAG S Sbjct: 405 GMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGS 464 Query: 361 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA-PGNARFG 419 LRLV G +C GR+EV + WGTVCDDSWD D+ VVCR+LGCG P RFG Sbjct: 465 PQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFG 524 Query: 420 QGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463 G+GPI LDDV C G E+ L CP W HNC H+ED GV C+ Sbjct: 525 WGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568 Score = 348 bits (894), Expect = 2e-95 Identities = 209/578 (36%), Positives = 268/578 (46%), Gaps = 105/578 (18%) Query: 873 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 932 A+ G ++ LRL +G C GR+EV + G WGTVCDD WD DA V CRQLGCG A++ Sbjct: 9 AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68 Query: 933 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA------- 985 APG A FG+G+GP+ L ++ C G+E L C H GW +H C H EDAGV+C+ Sbjct: 69 APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128 Query: 986 ----------------------------------------AQSQSTPRPDTWLTTNLPAL 1005 A + +PRP +T P L Sbjct: 129 DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188 Query: 1006 TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 1065 T G+ LRLV+G RC GR+EV + G WGTVCDD WD DA V CR+LGCG A++AP Sbjct: 189 TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248 Query: 1066 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT-------- 1117 G ARFG G+GP+ +DDV C G E L CP W NC H EDAG++C+ Sbjct: 249 GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLAD 308 Query: 1118 ---------------QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYP 1162 + S D W A CGG L G F Sbjct: 309 GPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIIL 368 Query: 1163 NNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF--DYVEIFDGSLNSSLLLGKICNDTR 1220 ++ +C G L F + H+C D + DG + LG + Sbjct: 369 DDLRC-------RGNETALRFCPARPWGQHDCHHREDAGAVCDG-----MPLGYVPPTAP 416 Query: 1221 QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-------------LRLVNLNSSY 1267 +S R A + P+ T LRLV S Sbjct: 417 TDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSK- 475 Query: 1268 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG---RAVSALGNAYFGSGSGPIT 1324 C+GR+E++H WGTVCDDSW ++++ VVCR+LGCG + A G FG G+GPI Sbjct: 476 --CSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGR--FGWGAGPIW 531 Query: 1325 LDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1362 LDDV C GTE++L C W HNC H ED GV C+G Sbjct: 532 LDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTG 569 Score = 143 bits (361), Expect = 1e-33 Identities = 64/128 (50%), Positives = 83/128 (64%) Query: 1002 LPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 1061 L A VG ++ LRL +G C GR+EV + G WGTVCDD WD DA V CRQLGCG A Sbjct: 7 LLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGA 66 Query: 1062 MSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINS 1121 ++APG A FG+G+GP+ L ++ C GNE L C H+GW H C H EDAGV+C+ ++ + Sbjct: 67 LAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVAN 126 Query: 1122 TTTDWWHP 1129 + D P Sbjct: 127 SRDDSTSP 134 Score = 138 bits (348), Expect = 4e-32 Identities = 78/198 (39%), Positives = 102/198 (51%), Gaps = 9/198 (4%) Query: 23 WIPRTTDYASLIPS---EVPLDTTVAEGSPFPSELTLESTVAEGSPISLESTLESTVAEG 79 W TT A+L P E T + P E+T EST+ SLE + E + EG Sbjct: 692 WTSHTT--ATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAE--IPEG 747 Query: 80 SL-IPSESTLESTVAEGSDSGL-ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDAN 137 S P + +V+ +SGL +RL +G RC GR+E+ + G WGTVCDD+WD DA Sbjct: 748 SPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807 Query: 138 VVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDA 197 V C +LGCG G +G G+GPI LDD+ C G E+ L CP W HNC H ED Sbjct: 808 VACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDV 867 Query: 198 GVICSAAQPQSTLRPESW 215 G+ C+ P +W Sbjct: 868 GLTCTGYTDYDDYPPWTW 885 Score = 138 bits (347), Expect = 5e-32 Identities = 65/146 (44%), Positives = 80/146 (54%), Gaps = 1/146 (0%) Query: 737 DTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQL 796 D P+ ST G +RL +G +RC GR+EV + G WGTVCDD+WD DA V C +L Sbjct: 754 DPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWEL 813 Query: 797 GCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSA 856 GCG G +G G+GPI LDD+ C G E+ L CP W HNC H ED G+ C+ Sbjct: 814 GCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873 Query: 857 SQSRPTPSPDTW-PTSRASTAGSEST 881 P TW PTSR A +T Sbjct: 874 YTDYDDYPPWTWDPTSREDLAKGTTT 899 Score = 136 bits (342), Expect = 2e-31 Identities = 63/143 (44%), Positives = 85/143 (59%), Gaps = 7/143 (4%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329 CAGR+E++HGG WGTVCDD W +++A V CRQLGCG A++A G A+FG G+GP+ L ++ Sbjct: 29 CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAGPVWLSELA 88 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQ 1389 C G E L C +RGW +H C+H EDAGV+C+G ++ + T P G L + Sbjct: 89 CRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRD--DSTSPLDGAPWPGLLLE 146 Query: 1390 PSGDFSSPFY-----PGNYPNNA 1407 S P P P NA Sbjct: 147 LSPSTEEPLVTHAPRPAGNPQNA 169 Score = 136 bits (342), Expect = 2e-31 Identities = 63/155 (40%), Positives = 81/155 (52%) Query: 858 QSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTND 917 + P D P+ ST G +RL +G +RC GR+EV + G WGTVCDD WD D Sbjct: 746 EGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRD 805 Query: 918 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 977 A V C +LGCG G +G G+GPI LDD+ C G E+ L CP W HNC H E Sbjct: 806 ATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEE 865 Query: 978 DAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESS 1012 D G+ C+ P TW T+ L G+ ++ Sbjct: 866 DVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTA 900 Score = 135 bits (341), Expect = 3e-31 Identities = 56/101 (55%), Positives = 73/101 (72%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329 CAGR+E++HGG WG+VCDD+W +++A V CR+LGCG A++A G A+FG GSGPI LDD+ Sbjct: 313 CAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLR 372 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAP 1370 C G E+ L C R W H+C+HREDAG +C G L P Sbjct: 373 CRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPP 413 Score = 134 bits (338), Expect = 6e-31 Identities = 72/187 (38%), Positives = 91/187 (48%), Gaps = 20/187 (10%) Query: 336 PQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395 P+ P D P+ ST G +RL +G +RC GR+EV + G WGTVCDD+WD Sbjct: 745 PEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLR 804 Query: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455 DA V C +LGCG G +G G+GPI LDD+ C G E+ L CP W HNC H Sbjct: 805 DATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHE 864 Query: 456 EDAGVICSA--------AHSWSTPSPDTL---------PTITLPASTV---GSESSLALR 495 ED G+ C+ +W S + L P TLP T GS S R Sbjct: 865 EDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIRR 924 Query: 496 LVNGGDR 502 L + G + Sbjct: 925 LPDTGSK 931 Score = 133 bits (334), Expect = 2e-30 Identities = 63/137 (45%), Positives = 75/137 (54%), Gaps = 1/137 (0%) Query: 220 SPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279 SP V T G +RL +G +RC GR+EV + G WGTVCDD WD DA V C +LGCG Sbjct: 758 SPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGK 817 Query: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339 G +G G+GPI LDD+ C G E+ L CP W HNC H ED G+ C+ Sbjct: 818 VRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDY 877 Query: 340 PTPSPDTW-PTSHASTA 355 P TW PTS A Sbjct: 878 DDYPPWTWDPTSREDLA 894 Score = 131 bits (330), Expect = 5e-30 Identities = 64/135 (47%), Positives = 83/135 (61%), Gaps = 10/135 (7%) Query: 1253 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1312 P LRLV S CAGR+E++HGG WGTVCDD W +++A V CR+LGCG A++A G Sbjct: 193 PRQERLRLV---SGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPG 249 Query: 1313 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL 1372 A FG G+GP+ +DDV C G E L C W NC+H EDAG++C+G PAP L Sbjct: 250 GARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG-----PAPRL 304 Query: 1373 NITRPNTDYSCGGFL 1387 + + + C G L Sbjct: 305 RLA--DGPHGCAGRL 317 Score = 130 bits (326), Expect = 1e-29 Identities = 63/148 (42%), Positives = 81/148 (54%), Gaps = 2/148 (1%) Query: 601 TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 660 +P P+ S ++ T G +RL +G +RC GR+EV + G WGTVCDD+WD DA Sbjct: 748 SPESPKDPAPSPSVSTT-GESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDA 806 Query: 661 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720 V C +LGCG G +G G+GPI LDD+ C G E+ L CP+ W HNC H ED Sbjct: 807 TVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEED 866 Query: 721 AGVICSAAQSRSTPRPDTW-PTSHASTA 747 G+ C+ P TW PTS A Sbjct: 867 VGLTCTGYTDYDDYPPWTWDPTSREDLA 894 Score = 128 bits (322), Expect = 4e-29 Identities = 61/138 (44%), Positives = 76/138 (55%), Gaps = 8/138 (5%) Query: 1006 TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 1065 T G +RL +G +RC GR+EV + G WGTVCDD+WD DA V C +LGCG Sbjct: 763 TTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV 822 Query: 1066 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTD 1125 G +G G+GPI LDD+ C G+E+ L CP W HNC H ED G+ C+ Sbjct: 823 GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPP 882 Query: 1126 W-WHPTT-------TTTA 1135 W W PT+ TTTA Sbjct: 883 WTWDPTSREDLAKGTTTA 900 Score = 127 bits (319), Expect = 1e-28 Identities = 56/125 (44%), Positives = 72/125 (57%) Query: 470 TPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 529 +P P + ST G +RL +G +RC GR+EV + G WGTVCDD+WD DA Sbjct: 748 SPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807 Query: 530 VVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDA 589 V C +LGCG G +G G+GPI LDD+ C G+E+ L CP W HNC H ED Sbjct: 808 VACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDV 867 Query: 590 GVICS 594 G+ C+ Sbjct: 868 GLTCT 872 Score = 122 bits (307), Expect = 2e-27 Identities = 50/112 (44%), Positives = 73/112 (65%) Query: 1251 SFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1310 S ++ L V L CAGR+E++H G WGTVCDD+W +++A V C +LGCG+ Sbjct: 762 STTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPR 821 Query: 1311 LGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1362 +G ++G G+GPI LDD+ C G+E++L C + W HNC+H ED G+ C+G Sbjct: 822 VGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873 >gi|4506143 neurotrypsin precursor [Homo sapiens] Length = 875 Score = 362 bits (930), Expect = 1e-99 Identities = 199/493 (40%), Positives = 249/493 (50%), Gaps = 62/493 (12%) Query: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421 ++RL G + +G VEV G WGTVC WD SDA+V+C QL G A G G Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228 Query: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481 PI +VRC G E + C + W C A V CS +H PT + Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279 Query: 482 PASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541 +RL G +GRVE+ + G WGTVCDD WD DA V+CRQLG Sbjct: 280 ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327 Query: 542 LAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPT 601 A A FG+GSGP++LD+VRC+GNE + CP + W HNCGH EDAGV C+ Sbjct: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380 Query: 602 PIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 661 P + +RL G +GR+EV YRG WGTVCDD W + Sbjct: 381 ------------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTY 422 Query: 662 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDA 721 VVCRQLG + A N F + +GPI LDDV CSG E+ C W H+C H ED Sbjct: 423 VVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDV 481 Query: 722 GVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 781 + C H + G +RL++G ++ +GRVEV G WGT+CD Sbjct: 482 SIACYPGGE-----------GHRLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICD 526 Query: 782 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 841 D W DA V+CRQLG A A FG+G GPI +D+V+C+G+E L C Sbjct: 527 DGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGR 586 Query: 842 HNCGHSEDAGVIC 854 HNC HSEDAGVIC Sbjct: 587 HNCRHSEDAGVIC 599 Score = 356 bits (913), Expect = 1e-97 Identities = 199/496 (40%), Positives = 246/496 (49%), Gaps = 68/496 (13%) Query: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160 ++RL G +G VE+ G WGTVC WD +DA+V+C QL G A + G G Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228 Query: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220 PI +VRC G E + C + W C A V CS + Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274 Query: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280 P P +RL G GRVE+ + G WGTVCDD WD DA V+CRQLG Sbjct: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326 Query: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340 A A FG+GSGP++LD+VRC+G+E + CP + W HNCGH EDAGV C Sbjct: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC------- 379 Query: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400 TP D +RL G +GR+EV YRG WGTVCDD W + VV Sbjct: 380 TPLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424 Query: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460 CRQLG + A N F + +GPI LDDV CSG E+ C W H+C H ED + Sbjct: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483 Query: 461 IC---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517 C H S P +RL++G ++ +GRVEV G WGT Sbjct: 484 ACYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGT 523 Query: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577 +CDD W DA V+CRQLG A A FG+G GPI +D+V+C+GNE L C Sbjct: 524 ICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQD 583 Query: 578 WLSHNCGHSEDAGVIC 593 HNC HSEDAGVIC Sbjct: 584 IGRHNCRHSEDAGVIC 599 Score = 354 bits (908), Expect = 5e-97 Identities = 196/490 (40%), Positives = 246/490 (50%), Gaps = 59/490 (12%) Query: 625 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 684 ++RL G + +G VEV G WGTVC WD +DA+V+C QL G A G G Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228 Query: 685 SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHA 744 PI +VRC G E + C + W C A V CS + + P Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278 Query: 745 STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 804 +RL G +GRVE+ + G WGTVCDD WD DA V+CRQLG A Sbjct: 279 ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329 Query: 805 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS 864 A FG+GSGP++LD+VRC+G+E + CP + W HNCGH EDAGV C TP Sbjct: 330 WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382 Query: 865 PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 924 D +RL G GR+EV Y+G WGTVCDD W + VVCRQ Sbjct: 383 TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427 Query: 925 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 984 LG + A N F + +GPI LDDV CSG E+ C W H+C H ED + C Sbjct: 428 LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486 Query: 985 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1044 L++G +RL++G ++ GRVEV G WGT+CDD W Sbjct: 487 PGGEGHR-------------LSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529 Query: 1045 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1104 DA V+CRQLG A A FG+G GPI +D+V+C+GNE L C + HNC Sbjct: 530 TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589 Query: 1105 GHHEDAGVIC 1114 H EDAGVIC Sbjct: 590 RHSEDAGVIC 599 Score = 352 bits (904), Expect = 1e-96 Identities = 197/493 (39%), Positives = 248/493 (50%), Gaps = 64/493 (12%) Query: 493 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 552 ++RL G + +G VEV G WGTVC WD +DA+V+C QL G +A G G Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228 Query: 553 SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSH 612 PI +VRC G+E + C + W C A V CS PI Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPI--------- 279 Query: 613 ALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 672 +RL G +GRVE+ + G WGTVCDD WD DA V+CRQLG Sbjct: 280 -------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326 Query: 673 TSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRS 732 A A FG+GSGP++LD+VRC+G+E + CP + W HNCGH EDAGV C Sbjct: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC------- 379 Query: 733 TPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVV 792 TP D +RL G +GR+EV Y+G WGTVCDD W + VV Sbjct: 380 TPLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424 Query: 793 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGV 852 CRQLG + A N F + +GPI LDDV CSG E+ C W H+C H ED + Sbjct: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483 Query: 853 ICSASQSRPTPSPDTWPTSRASTAGSESTLA--LRLVNGGDRCRGRVEVLYQGSWGTVCD 910 C +P G +L +RL++G ++ GRVEV G WGT+CD Sbjct: 484 AC-------------YPGGE----GHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICD 526 Query: 911 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 970 D W DA V+CRQLG A A FG+G GPI +D+V+C+G+E L C Sbjct: 527 DGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGR 586 Query: 971 HNCGHHEDAGVIC 983 HNC H EDAGVIC Sbjct: 587 HNCRHSEDAGVIC 599 Score = 261 bits (666), Expect = 6e-69 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%) Query: 883 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 942 ++RL G + G VEV G WGTVC +WD +DA+V+C QL G A G G Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228 Query: 943 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1002 PI +VRC G E + C + W C A V CS + + P Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278 Query: 1003 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1062 +RL G GRVE+ + G WGTVCDD WD DA V+CRQLG Sbjct: 279 -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327 Query: 1063 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1122 A A FG+GSGP++LD+VRC+GNE + CP W HNCGH EDAGV C+ Sbjct: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380 Query: 1123 TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1178 P T R S+ G Y G + + + N V Sbjct: 381 ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426 Query: 1179 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1237 LGF + A+H F+ S L C+ F R R D Sbjct: 427 -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474 Query: 1238 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1292 S + +A Y P RL V L GRVE++ G WGT+CDD WT Sbjct: 475 CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531 Query: 1293 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1352 ++A V+CRQLG A AYFG G GPI +D+V+C+G E +L C + HNC H Sbjct: 532 KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591 Query: 1353 REDAGVIC 1360 EDAGVIC Sbjct: 592 SEDAGVIC 599 Score = 149 bits (375), Expect = 3e-35 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%) Query: 1014 ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1073 ++RL G + G VEV G WGTVC WD +DA+V+C QL G A G G Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228 Query: 1074 SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1133 PI +VRC G+E + C W C A V CS + + P Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282 Query: 1134 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1193 S + G Y +G + + + +A+ + LG S + +A H Sbjct: 283 AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332 Query: 1194 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1248 F G + ++L ++ C Q SS+ + D T Sbjct: 333 AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382 Query: 1249 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1308 +D +RL S+ GR+E+Y+ G WGTVCDD WT VVCRQLG Sbjct: 383 -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434 Query: 1309 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1364 A N +F +GPI LDDV CSG E+ QC R W H+C+HRED + C G+ Sbjct: 435 QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493 Query: 1365 LSTPAP 1370 LS P Sbjct: 494 LSLGFP 499 Score = 112 bits (280), Expect = 3e-24 Identities = 50/103 (48%), Positives = 66/103 (64%) Query: 99 GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158 G +RL++G+ + +GRVE+ G WGT+CDD W DA V+CRQLG A A+FG Sbjct: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556 Query: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201 +G GPI +D+V+C+G+E L C HNC H EDAGVIC Sbjct: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599 >gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens] Length = 607 Score = 296 bits (759), Expect = 9e-80 Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%) Query: 1373 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 1431 NI+ PN CGG+L G F+SP YP +P A CVW I+V+ +Y++ + F+++ LE Sbjct: 148 NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203 Query: 1432 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 1490 C +D++ ++DGP +S LI +VC +F SSSN +++ +D++ + RGF A Y Sbjct: 204 DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263 Query: 1491 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 1548 S + + ++T+L C + M+ +S+SYL++ + ++L + CRP+++ N+V F Sbjct: 264 SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318 Query: 1549 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 1606 ++P +GCGT ++ ++ +I Y+N +T A+ + +I R+ L+I V C M N+ V+ +YI Sbjct: 319 SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378 Query: 1607 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 1666 D + + N + G ++ +++ + S+SF + PYYVDLNQ L+VQ + S Sbjct: 379 TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431 Query: 1667 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 1726 D L +F+DTC ASP S DF S TYDLI+SGC RD+T Y RF+F AF FL Sbjct: 432 DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489 Query: 1727 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 1778 SVYL+CK+++C + D SRC +GCV RSKRD+ SY+ K D ++GPI+L+ Sbjct: 490 SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541 Score = 97.4 bits (241), Expect = 1e-19 Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%) Query: 1140 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1199 NCGG+L G+F+SP+YP +P A CVW I+V Y+I L F + LE C FD++ Sbjct: 153 NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212 Query: 1200 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1259 I+DG +S L+G++C F SS N +T+ +D + GF A Y S ++ Sbjct: 213 AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268 Query: 1260 LVNLNSSYGLCA 1271 N+N++ C+ Sbjct: 269 --NINTTSLTCS 278 Score = 52.0 bits (123), Expect = 5e-06 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%) Query: 1409 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 1464 C W IE N + +IF VQL+ G C + I+VFDG + PL+ +VC + F Sbjct: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117 Query: 1465 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 1494 SSS+ ++ + ++D + I R F Y+ SP+ Sbjct: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148 Score = 50.4 bits (119), Expect = 2e-05 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Query: 1167 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1224 C W IE I + FS ++L+ +C + +++FDG+ ++ LLG++C ND +F Sbjct: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117 Query: 1225 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1254 SS + +T +D + Q T F+ +Y P+ Sbjct: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148 >gi|5174411 CD5 molecule-like [Homo sapiens] Length = 347 Score = 269 bits (688), Expect = 2e-71 Identities = 147/371 (39%), Positives = 186/371 (50%), Gaps = 50/371 (13%) Query: 751 SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 810 S +RLV G RC+GRVEV +G WGTVCDD WD D V+CR+LGCG A P + Sbjct: 20 SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79 Query: 811 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT 867 + +++ V C+G E L C ++C H EDAG C +S +P P+ Sbjct: 80 EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136 Query: 868 WPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGC 927 +RL +G C+GRVEV +Q W TVC W A VVCRQLGC Sbjct: 137 ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181 Query: 928 GWAMSAPGNA-QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAA 986 G A+ + G PI L + CSG E+ L CP W + C H ED V C Sbjct: 182 GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238 Query: 987 QSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDT 1046 E LRLV G + C GR+EVL++G WG+VCDD+W Sbjct: 239 -----------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGE 275 Query: 1047 NDANVVCRQLGCGWAMSAPGNAR--FGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1104 + VVC+QLGCG ++S R +G G G I LD+VRCSG E L C H+ W H+C Sbjct: 276 KEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDC 335 Query: 1105 GHHEDAGVICS 1115 H ED VICS Sbjct: 336 THQEDVAVICS 346 Score = 267 bits (683), Expect = 6e-71 Identities = 146/371 (39%), Positives = 183/371 (49%), Gaps = 50/371 (13%) Query: 230 SSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF 289 S +RLV G RC GRVEV +G WGTVCDD WD D V+CR+LGCG A P + Sbjct: 20 SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79 Query: 290 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346 + +++ V C+G E L C ++C H EDAG C P+S +P P+ Sbjct: 80 EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136 Query: 347 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGC 406 +RL +G C+GRVEV ++ W TVC W A VVCRQLGC Sbjct: 137 ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181 Query: 407 GWATSAPGNA-RFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA 465 G A + G PI L + CSG E+ L CP W + C H ED V C Sbjct: 182 GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238 Query: 466 HSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 525 E LRLV G + C GR+EVL++G WG+VCDD+W Sbjct: 239 -----------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGE 275 Query: 526 NDANVVCRQLGCGWAMLAPGNAR--FGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNC 583 + VVC+QLGCG ++ R +G G G I LD+VRCSG E L C H W H+C Sbjct: 276 KEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDC 335 Query: 584 GHSEDAGVICS 594 H ED VICS Sbjct: 336 THQEDVAVICS 346 Score = 266 bits (681), Expect = 1e-70 Identities = 146/374 (39%), Positives = 185/374 (49%), Gaps = 53/374 (14%) Query: 359 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF 418 S +RLV G RC+GRVEV +G WGTVCDD WD D V+CR+LGCG A+ P + Sbjct: 20 SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79 Query: 419 ---GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDT 475 + +++ V C+G E L C ++C H EDAG C S +P P+ Sbjct: 80 EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136 Query: 476 LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 535 +RL +G C+GRVEV ++ W TVC W A VVCRQL Sbjct: 137 -----------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQL 179 Query: 536 GCGWAMLAPGNA-RFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594 GCG A+L + G PI L + CSG E+ L CP W + C H ED V C Sbjct: 180 GCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC- 238 Query: 595 ALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 654 E LRLV G + C GR+EVL++G WG+VCDD+ Sbjct: 239 --------------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDN 272 Query: 655 WDTNDANVVCRQLGCGWATSAPGNAR--FGQGSGPIVLDDVRCSGHESYLWSCPNNGWLS 712 W + VVC+QLGCG + S R +G G G I LD+VRCSG E L C + W Sbjct: 273 WGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGF 332 Query: 713 HNCGHHEDAGVICS 726 H+C H ED VICS Sbjct: 333 HDCTHQEDVAVICS 346 Score = 264 bits (675), Expect = 5e-70 Identities = 147/377 (38%), Positives = 186/377 (49%), Gaps = 61/377 (16%) Query: 490 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 549 S +RLV G RC+GRVEV +G WGTVCDD WD D V+CR+LGCG A P + Sbjct: 20 SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79 Query: 550 ---GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPR 606 + +++ V C+G E L C ++C H EDAG Sbjct: 80 EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGA--------------- 122 Query: 607 SWPSSHALQTCKGPESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 661 +C+ PESS + +RL +G C+GRVEV ++ W TVC W A Sbjct: 123 ---------SCENPESSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAK 173 Query: 662 VVCRQLGCGWATSAPGNA-RFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720 VVCRQLGCG A + G PI L + CSG E+ L CP+ W + C H ED Sbjct: 174 VVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDED 233 Query: 721 AGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 780 V C E LRLV G + C GR+EVL++G WG+VC Sbjct: 234 TWVEC------------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVC 269 Query: 781 DDSWDTNDANVVCRQLGCGWAMSAPGNAR--FGQGSGPIVLDDVRCSGHESYLWSCPHNG 838 DD+W + VVC+QLGCG ++S R +G G G I LD+VRCSG E L C H Sbjct: 270 DDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRF 329 Query: 839 WLSHNCGHSEDAGVICS 855 W H+C H ED VICS Sbjct: 330 WGFHDCTHQEDVAVICS 346 Score = 262 bits (670), Expect = 2e-69 Identities = 148/368 (40%), Positives = 185/368 (50%), Gaps = 51/368 (13%) Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWF---G 158 +RLV G RC+GRVE+ +G WGTVCDD WD D V+CR+LGCG A P + Sbjct: 24 VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83 Query: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVR 218 + + + V C+G E L C ++C H EDAG C P+S+ Sbjct: 84 EKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCE--NPESSF-------- 131 Query: 219 ISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCG 278 PVP EG +RL +G C+GRVEV ++ W TVC W A VVCRQLGCG Sbjct: 132 --SPVP-EG------VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCG 182 Query: 279 WAMSAPGNA-QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQ 337 A+ + G PI L + CSG E+ L CP W + C H ED V C P Sbjct: 183 RAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDP- 241 Query: 338 SRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDA 397 LRLV G + C GR+EVL++G WG+VCDD+W + Sbjct: 242 -----------------------FDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKED 278 Query: 398 NVVCRQLGCGWATSAPGNAR--FGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455 VVC+QLGCG + S R +G G G I LD+VRCSG E L C H W H+C H Sbjct: 279 QVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQ 338 Query: 456 EDAGVICS 463 ED VICS Sbjct: 339 EDVAVICS 346 Score = 114 bits (286), Expect = 6e-25 Identities = 54/107 (50%), Positives = 74/107 (69%), Gaps = 5/107 (4%) Query: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA--LGNAY 1315 LRLV ++ LC+GR+E+ H G WG+VCDD+W +E +VVC+QLGCG+++S Sbjct: 244 LRLVGGDN---LCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKC 300 Query: 1316 FGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1362 +G G G I LD+V CSG E +L QC++R W H+C H+ED VICSG Sbjct: 301 YGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG 347 Score = 92.0 bits (227), Expect = 5e-18 Identities = 46/101 (45%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Query: 1261 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSG 1319 V L G C GRVE+ H W TVC W+++ A+VVCRQLGCGRAV G Sbjct: 138 VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYG 197 Query: 1320 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360 PI L + CSG E+TL C + W + CNH ED V C Sbjct: 198 RKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC 238 Score = 84.7 bits (208), Expect = 7e-16 Identities = 42/105 (40%), Positives = 55/105 (52%), Gaps = 6/105 (5%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF---GSGSGPITLD 1326 C GRVE+ G WGTVCDD W I++ V+CR+LGCG A + + + Sbjct: 33 CEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQ 92 Query: 1327 DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLS-TPAP 1370 V C+GTE TL QC ++C+H EDAG C S +P P Sbjct: 93 SVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVP 135 >gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] Length = 756 Score = 269 bits (688), Expect = 2e-71 Identities = 193/538 (35%), Positives = 252/538 (46%), Gaps = 87/538 (16%) Query: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160 LRLV + + + GR+E+L++G WGTVCDD++ +A V CRQLG A++ +A +GQG Sbjct: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91 Query: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206 GPI LD+VRC G ES L C NGW +C H ED GVIC +A P Sbjct: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151 Query: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266 Q E VR+ P + + S + G VEV Y G W VCD W N Sbjct: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198 Query: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308 ++ VVC L G+ P ++ + + + + D V C G E Sbjct: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256 Query: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGSESSLA 362 ++ +C P G L C A V C A P RP P T P S A Sbjct: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310 Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422 +RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG Sbjct: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370 Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLP 482 GPI L +VRC GYE L CP + CQH DA V C + P+ + L Sbjct: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLA 424 Query: 483 ASTVGSESSLALRL-VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541 + E L +++ VNG R WG+VC ++W +A V CRQLG G+A+ Sbjct: 425 GGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAI 472 Query: 542 LAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED---AGVIC 593 A F G + +V+ VRCSG E L C +G + +C H AGV C Sbjct: 473 HAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528 Score = 265 bits (676), Expect = 4e-70 Identities = 198/558 (35%), Positives = 261/558 (46%), Gaps = 72/558 (12%) Query: 467 SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDS 522 +WS P+ L + L P S S + LRLV + + GR+EVL++G WGTVCDD+ Sbjct: 2 AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61 Query: 523 WDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN 582 + +A V CRQLG A+ +A++GQG GPI LD+VRC G ES L C NGW + Sbjct: 62 FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121 Query: 583 CGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPE----SSLALRLVNGGDR---- 634 C HSED GVIC P R R + S + GP+ + L+ + + Sbjct: 122 CSHSEDVGVICH-------PRRHRGY-LSETVSNALGPQGRRLEEVRLKPILASAKQHSP 173 Query: 635 -CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD- 692 +G VEV Y G W VCD W N++ VVC L G+ + P ++ + + + + D Sbjct: 174 VTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDP 231 Query: 693 -----------------VRCSGHESYLWSC-----PNNGWLSHNCGHHEDAGVICSAAQS 730 V C G E ++ +C P G L C A V C A Sbjct: 232 KSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPH 291 Query: 731 RSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDAN 790 P+ T P S A +RL +G +GRVEVL WGTVCD W+ A+ Sbjct: 292 FRPPK--TKPQRKGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISAS 346 Query: 791 VVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDA 850 VVCRQLG G A A AR GQG GPI L +VRC G+E L CP + C H DA Sbjct: 347 VVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDA 406 Query: 851 GVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCD 910 V C+ P+ ++ AG R+ G +VEV WG+VC Sbjct: 407 AVRCNV--------PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCS 451 Query: 911 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG 967 + W +A V CRQLG G+A+ A F G + +V+ VRCSG E L C +G Sbjct: 452 ENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHG 511 Query: 968 --WLSHNCGHHEDAGVIC 983 SH G AGV C Sbjct: 512 PVHCSHGGGRFL-AGVSC 528 Score = 259 bits (662), Expect = 2e-68 Identities = 189/550 (34%), Positives = 253/550 (46%), Gaps = 75/550 (13%) Query: 600 PTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTND 659 P P RP+S ++ GPES +GR+EVL++G WGTVCDD++ + Sbjct: 19 PPPSRPQSLGTTKLRLV--GPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQE 66 Query: 660 ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHE 719 A V CRQLG A + +A++GQG GPI LD+VRC G ES L C +NGW +C H E Sbjct: 67 ATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSE 126 Query: 720 DAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR-----CQGRVEVLYQG 774 D GVIC + R +T + + L+ + + +G VEV Y+G Sbjct: 127 DVGVICHPRRHRGY-LSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEG 185 Query: 775 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD------------- 821 W VCD W N++ VVC LG + P ++ + + + + D Sbjct: 186 HWRQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNS 243 Query: 822 -----VRCSGHESYLWSC-----PHNGWLSHNCGHSEDAGVICSASQS-RPTPSPDTWPT 870 V C G E ++ +C P G L C A V C A RP P T P Sbjct: 244 FWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQ 300 Query: 871 SRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 930 + S A +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A Sbjct: 301 RKGSWAEEPR---VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSA 357 Query: 931 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQS 990 A A+ GQG GPI L +VRC G+E L CP + C H DA V C Sbjct: 358 REALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------- 410 Query: 991 TPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDAN 1050 N+P + ++ LA + +VEV WG+VC ++W +A Sbjct: 411 ----------NVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAM 460 Query: 1051 VVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHH 1107 V CRQLG G+A+ A F G + +V+ VRCSG E L C G + +C H Sbjct: 461 VACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHG 518 Query: 1108 ED---AGVIC 1114 AGV C Sbjct: 519 GGRFLAGVSC 528 Score = 256 bits (655), Expect = 1e-67 Identities = 187/538 (34%), Positives = 241/538 (44%), Gaps = 61/538 (11%) Query: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279 PP S + LRLV + GR+EVL++G WGTVCDD + +A V CRQLG Sbjct: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78 Query: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339 A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + R Sbjct: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138 Query: 340 ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395 T S P + +G VEV Y G W VCD W + Sbjct: 139 GYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMN 198 Query: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGYES 437 ++ VVC L G+ + P ++ + + + + D V C G E Sbjct: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256 Query: 438 YLWSC-----PHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 492 ++ +C P G L C A V C A P P T P Sbjct: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVA-------GPHFRPPKTKPQRKGSWAEEP 309 Query: 493 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 552 +RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG Sbjct: 310 RVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQG 369 Query: 553 SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSH 612 GPI L +VRC G E L CP + C H DA V C+ + + + Sbjct: 370 LGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN--------VPNMGFQNQV 421 Query: 613 ALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 672 L + PE L + +VEV WG+VC ++W +A V CRQLG G+A Sbjct: 422 RLAGGRIPEEGL----------LEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFA 471 Query: 673 TSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNG--WLSHNCGHHEDAGVIC 725 A F G + +V+ VRCSG E L C +G SH G AGV C Sbjct: 472 IHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFL-AGVSC 528 Score = 216 bits (551), Expect = 1e-55 Identities = 147/404 (36%), Positives = 186/404 (46%), Gaps = 40/404 (9%) Query: 740 PTSHASTAGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 798 P S + G+ LRLV + + GR+EVL+QG WGTVCDD++ +A V CRQLG Sbjct: 20 PPSRPQSLGTTK---LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGF 76 Query: 799 GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQ 858 A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + Sbjct: 77 EAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRR 136 Query: 859 SR----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWD 914 R T S P R + G VEV Y+G W VCD W Sbjct: 137 HRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWT 196 Query: 915 TNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGH 956 N++ VVC L G+ P ++ + + + + D V C G Sbjct: 197 MNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGT 254 Query: 957 ESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSES 1011 E ++ +C P G L C A V C A P+ P Sbjct: 255 EPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK-------TKPQRKGSWAE 307 Query: 1012 SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 1071 +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A A AR G Sbjct: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367 Query: 1072 QGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1115 QG GPI L +VRC G E L CP + C H DA V C+ Sbjct: 368 QGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411 Score = 110 bits (276), Expect = 9e-24 Identities = 50/89 (56%), Positives = 63/89 (70%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331 GR+E+ H G WGTVCDD++ IQEA V CRQLG A++ +A +G G GPI LD+V C Sbjct: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103 Query: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1360 GTES+L QC + GW +C+H ED GVIC Sbjct: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132 Score = 87.8 bits (216), Expect = 9e-17 Identities = 46/101 (45%), Positives = 52/101 (51%) Query: 1261 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1320 V L S + GRVE+ WGTVCD W + A VVCRQLG G A AL A G G Sbjct: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370 Query: 1321 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 GPI L +V C G E TL C + C H DA V C+ Sbjct: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411 Score = 68.6 bits (166), Expect = 5e-11 Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%) Query: 1268 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1324 GL +VE+ WG+VC ++W + EA V CRQLG G A+ A +F SG + + Sbjct: 432 GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491 Query: 1325 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1360 + V CSGTE L QC+ G +C+H R AGV C Sbjct: 492 MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528 Score = 39.3 bits (90), Expect = 0.035 Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1317 G VE+ + G W VCD WT+ + VVC LG V + Y Sbjct: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236 Query: 1318 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1368 + + V C GTE + C+ RG C A V C +G H P Sbjct: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295 >gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] Length = 753 Score = 261 bits (667), Expect = 4e-69 Identities = 193/556 (34%), Positives = 256/556 (46%), Gaps = 71/556 (12%) Query: 460 VICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR-CQGRVEVLYRGSWGTV 518 ++CS+ +PSP T P GS+ L RL + +GRVE+ G WGT+ Sbjct: 18 LLCSSC--LGSPSPSTGPE-----KKAGSQG-LRFRLAGFPRKPYEGRVEIQRAGEWGTI 69 Query: 519 CDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGW 578 CDD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW Sbjct: 70 CDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGW 129 Query: 579 LSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDR---- 634 + +C H EDAGVIC Q LP H LQ + +R G R Sbjct: 130 GNSDCTHDEDAGVICKD-QRLPGFSDSNVIEVEHHLQV-----EEVRIRPAVGWGRRPLP 183 Query: 635 -CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPI 688 +G VEV W VCD W ++++VVC LG + + NA F + Sbjct: 184 VTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSF 241 Query: 689 VLDDVRCSGHESYLWSCPNNGWLSHN---CGHHEDAGVICS-----AAQSRSTPRPDTWP 740 L V C G E++L C + +++ C A V C AA S + + P Sbjct: 242 GLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP 301 Query: 741 TSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGW 800 A +RL G +GRVEVL +WGTVCD WD + A+VVCR+LG G Sbjct: 302 QGEAR---------VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGS 352 Query: 801 AMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSR 860 A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+ Sbjct: 353 AREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL---- 408 Query: 861 PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG----SWGTVCDDYWDTN 916 P + A T +RL G + GRVEV G WG +C D W T Sbjct: 409 --------PYTGAET-------RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTL 453 Query: 917 DANVVCRQLGCGWAMSAPGNAQFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHN 972 +A V CRQLG G+A + +V+ VRC+G E L C H+G Sbjct: 454 EAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKR 513 Query: 973 CGHHEDAGVICSAAQS 988 G AGVICS S Sbjct: 514 TGTRFTAGVICSETAS 529 Score = 260 bits (665), Expect = 7e-69 Identities = 172/502 (34%), Positives = 234/502 (46%), Gaps = 49/502 (9%) Query: 636 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 695 +GRVE+ G WGT+CDD + A+++CR+LG AT +A++G G+G I LD++ C Sbjct: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114 Query: 696 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLAL 755 SG E + C + GW + +C H EDAGVIC + + H + + Sbjct: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRI 171 Query: 756 RLVNGGDR-----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 810 R G R +G VEV W VCD W ++++VVC LG + NA F Sbjct: 172 RPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAF 229 Query: 811 -----GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSP 865 + L V C G E++L C + +++ G + P + Sbjct: 230 YRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAA 289 Query: 866 DTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQL 925 + + + + +RL G GRVEVL +WGTVCD WD + A+VVCR+L Sbjct: 290 SSGQKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCREL 348 Query: 926 GCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA 985 G G A A A+ GQG G I L +VRCSG E LW CPH + +C H +DAGV C Sbjct: 349 GFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC-- 406 Query: 986 AQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCD 1041 NLP G+E+ + RL G + GRVEV G WG +C Sbjct: 407 ---------------NLPY--TGAETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICG 447 Query: 1042 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGW 1099 D W T +A V CRQLG G+A + +V+ VRC+G E L C H G Sbjct: 448 DDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG- 506 Query: 1100 LTH----NCGHHEDAGVICSAT 1117 TH G AGVICS T Sbjct: 507 -THITCKRTGTRFTAGVICSET 527 Score = 253 bits (646), Expect = 1e-66 Identities = 184/555 (33%), Positives = 252/555 (45%), Gaps = 53/555 (9%) Query: 59 TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117 +V + SP L L + GS PS ST + GL RL + +GRVEI Sbjct: 5 SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60 Query: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177 G WGT+CDD + A+++CR+LG A +A +G G+G I LD++ CSG E Sbjct: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120 Query: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237 + C GW + +C H EDAGVIC + +S + + + E + +R Sbjct: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174 Query: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289 G R G VEV W VCD W ++++VVC LG + NA F Sbjct: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRL 232 Query: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347 + L V C G E++L C + ++ G + P + + Sbjct: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292 Query: 348 PTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407 + + +RL G +GRVEVL +WGTVCD WD A+VVCR+LG G Sbjct: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351 Query: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467 A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+ ++ Sbjct: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411 Query: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDSW 523 G+E+ +RL G + +GRVEV G WG +C D W Sbjct: 412 -------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDW 450 Query: 524 DTNDANVVCRQLGCGWAMLAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHNGW--L 579 T +A V CRQLG G+A + +V+ VRC+G E L C H+G Sbjct: 451 GTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHIT 510 Query: 580 SHNCGHSEDAGVICS 594 G AGVICS Sbjct: 511 CKRTGTRFTAGVICS 525 Score = 208 bits (530), Expect = 3e-53 Identities = 142/415 (34%), Positives = 190/415 (45%), Gaps = 31/415 (7%) Query: 723 VICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYQGSWGTVC 780 ++CS+ +P P T P A + G LA G R +GRVE+ G WGT+C Sbjct: 18 LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70 Query: 781 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 840 DD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW Sbjct: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130 Query: 841 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR----CRGR 896 + +C H EDAGVIC R D+ E V G R G Sbjct: 131 NSDCTHDEDAGVICK--DQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGL 188 Query: 897 VEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDDV 951 VEV W VCD W ++++VVC LG + NA F + L V Sbjct: 189 VEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGV 246 Query: 952 RCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVG 1008 C G E++L C + +++ C A V C + + P Sbjct: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP----- 301 Query: 1009 SESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 1068 + +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A A Sbjct: 302 -QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA 360 Query: 1069 RFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 1123 R GQG G I L +VRCSG E LW CPHK +C H +DAGV C+ + T Sbjct: 361 RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415 Score = 107 bits (266), Expect = 1e-22 Identities = 46/94 (48%), Positives = 63/94 (67%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331 GRVEI G WGT+CDD +T+Q A ++CR+LG A +A +G G+G I LD++ CS Sbjct: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115 Query: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1365 GTE ++ +C +RGW + +C H EDAGVIC L Sbjct: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149 Score = 99.8 bits (247), Expect = 2e-20 Identities = 44/90 (48%), Positives = 57/90 (63%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331 GRVE+ TWGTVCD W + A VVCR+LG G A AL A G G G I L +V CS Sbjct: 318 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377 Query: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 G E +LW+C ++ + +C+H +DAGV C+ Sbjct: 378 GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407 Score = 63.9 bits (154), Expect = 1e-09 Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%) Query: 1272 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1325 GRVE+ GG WG +C D W EA V CRQLG G A L Y+ SG+ + + Sbjct: 428 GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487 Query: 1326 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1361 V C+GTE +L QC + G R AGVICS Sbjct: 488 SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525 Score = 34.7 bits (78), Expect = 0.85 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1328 G VE+ W VCD W+ + VVC LG R +A L V Sbjct: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246 Query: 1329 ECSGTESTLWQC 1340 C GTE+ L C Sbjct: 247 ACVGTEAHLSLC 258 >gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] Length = 774 Score = 256 bits (654), Expect = 1e-67 Identities = 190/578 (32%), Positives = 266/578 (46%), Gaps = 81/578 (14%) Query: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241 C H + + P S + +SWP P P + + + LRL Sbjct: 6 CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65 Query: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300 + GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD+ Sbjct: 66 KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125 Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360 + C+G+E+ L +C NGW +C H+ED GV+CS + ++ + Sbjct: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185 Query: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415 + +R + R +G VEV +W +CD W ++ VVC G PG Sbjct: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239 Query: 416 ------------ARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN------CQHSED 457 +R Q P +D C+G E+++ SC +S + C++ Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296 Query: 458 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517 A V C +S P P + +RL G +GRVEVL G WGT Sbjct: 297 AVVSCVPGQVFSPDGPSRFRKAYKPEQPL-------VRLRGGAYIGEGRVEVLKNGEWGT 349 Query: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577 VCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+GNE + C N Sbjct: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409 Query: 578 WLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQG 637 S C H EDAGV C+ TP + LQ LRL G + +G Sbjct: 410 -ESQGCNHEEDAGVRCN------TP--------AMGLQK--------KLRLNGGRNPYEG 446 Query: 638 RVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVL 690 RVEVL + WG VC +W +A VVCRQLG G+A++A + G S +V+ Sbjct: 447 RVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVM 506 Query: 691 DDVRCSGHESYLWSCPNNG--WLSHNCGHHEDAGVICS 726 V+CSG E L C ++G G AGV CS Sbjct: 507 SGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544 Score = 255 bits (652), Expect = 2e-67 Identities = 181/514 (35%), Positives = 245/514 (47%), Gaps = 68/514 (13%) Query: 636 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 695 +GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C Sbjct: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128 Query: 696 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLAL 755 +G+E+ L +C +NGW +C H ED GV+CS + ++ + + + Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188 Query: 756 RLVNGGDR-----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN--- 807 R + R +G VEV +W +CD W ++ VVC G PG Sbjct: 189 RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242 Query: 808 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHSEDAGV 852 +R Q P +D C+G E+++ SC +S + C + A V Sbjct: 243 NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299 Query: 853 ICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 912 C Q SPD SR A +RL G GRVEVL G WGTVCDD Sbjct: 300 SCVPGQ---VFSPD--GPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354 Query: 913 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 972 WD A+VVCR+LG G A A ++ GQG GPI L++++C+G+E + C N S Sbjct: 355 WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413 Query: 973 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 1032 C H EDAGV C N PA+ + + LRL G + GRVEVL Sbjct: 414 CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452 Query: 1033 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 1085 + WG VC +W +A VVCRQLG G+A +A + G S +V+ V+CS Sbjct: 453 ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512 Query: 1086 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 1117 G E L C H G G AGV CS T Sbjct: 513 GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546 Score = 254 bits (649), Expect = 5e-67 Identities = 180/519 (34%), Positives = 248/519 (47%), Gaps = 79/519 (15%) Query: 373 QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432 +GRVEV Y G WGTVCDD + A+VVCR+LG A S ++ +G+G GPI LD++ C Sbjct: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128 Query: 433 SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 492 +G E+ L +C NGW +C+H+ED GV+C S +P S + +L Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVC---------SDKRIPGFKFDNSLINQIENL 179 Query: 493 ALRLVNGGDRC------------QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG-- 538 +++ + R +G VEV +W +CD W ++ VVC G Sbjct: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGE 239 Query: 539 -------WAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN------CGH 585 + M A +R Q P +D C+G E+++ SC +S + C + Sbjct: 240 RTYNTKVYKMFA---SRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCEN 293 Query: 586 SEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRG 645 A V C +P + PS + PE L +RL G +GRVEVL G Sbjct: 294 GLPAVVSC-----VPGQVFSPDGPS--RFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNG 345 Query: 646 SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 705 WGTVCDD WD A+VVCR+LG G A A +R GQG GPI L++++C+G+E + C Sbjct: 346 EWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC 405 Query: 706 PNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQ 765 N S C H EDAGV C +T LRL G + + Sbjct: 406 KFNA-ESQGCNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYE 445 Query: 766 GRVEVLYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIV 818 GRVEVL + + WG VC +W +A VVCRQLG G+A +A + G S +V Sbjct: 446 GRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVV 505 Query: 819 LDDVRCSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 855 + V+CSG E L C H+G G AGV CS Sbjct: 506 MSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544 Score = 248 bits (632), Expect = 5e-65 Identities = 181/515 (35%), Positives = 246/515 (47%), Gaps = 71/515 (13%) Query: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171 +GRVE+ Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C Sbjct: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128 Query: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231 +G+E+ L +C NGW +C H ED GV+CS + S +I Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIEN---LNIQVED 185 Query: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286 + +R + R R G VEV +W +CD +W ++ VVC G PG Sbjct: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239 Query: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328 + Q P +D C+G E+++ SC ++ + C + Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296 Query: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388 A V C Q SPD P+ E L +RL G +GRVEVL G WGTVC Sbjct: 297 AVVSCVPGQ---VFSPDG-PSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351 Query: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448 DD WD A+VVCR+LG G A A +R GQG GPI L++++C+G E + C N Sbjct: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410 Query: 449 SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508 S C H EDAGV C +TP+ +G + LRL G + +GRVE Sbjct: 411 SQGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVE 449 Query: 509 VLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGPIVLDDV 561 VL + WG VC +W +A VVCRQLG G+A A + G S +V+ V Sbjct: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509 Query: 562 RCSGNESYLWSCPHNG--WLSHNCGHSEDAGVICS 594 +CSG E L C H+G G AGV CS Sbjct: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544 Score = 145 bits (366), Expect = 3e-34 Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%) Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161 +RL G +GRVE+L G WGTVCDD WD A+VVCR+LG G A A + GQG Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385 Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221 GPI L++++C+G+E + C N S C H EDAGV C+ Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425 Query: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277 P G + LRL G + GRVEVL + WG VC W +A VVCRQLG Sbjct: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482 Query: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332 G+A +A + G S +V+ V+CSG E L C H+G G AGV Sbjct: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542 Query: 333 CS 334 CS Sbjct: 543 CS 544 Score = 107 bits (266), Expect = 1e-22 Identities = 46/94 (48%), Positives = 62/94 (65%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331 GRVE+Y+ G WGTVCDD ++I A VVCR+LG A S ++ +G G GPI LD++ C+ Sbjct: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129 Query: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1365 G E+TL C + GW +C H ED GV+CS + Sbjct: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163 Score = 103 bits (256), Expect = 2e-21 Identities = 47/94 (50%), Positives = 63/94 (67%) Query: 1026 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1085 GRVEV Y G WGTVCDD + + A+VVCR+LG A S ++ +G+G GPI LD++ C+ Sbjct: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129 Query: 1086 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 1119 GNE+ L +C GW +C H ED GV+CS +I Sbjct: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163 Score = 98.2 bits (243), Expect = 6e-20 Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%) Query: 1260 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1319 LV L + GRVE+ G WGTVCDD W + A VVCR+LG G A A+ + G G Sbjct: 325 LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384 Query: 1320 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 GPI L++++C+G E ++ C+ S CNH EDAGV C+ Sbjct: 385 IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425 Score = 63.5 bits (153), Expect = 2e-09 Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%) Query: 1253 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1308 P+ + + LN GRVE+ +G WG VC +W I EA VVCRQLG G A Sbjct: 427 PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486 Query: 1309 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1344 +A ++ G S + + V+CSGTE +L CR+ G Sbjct: 487 NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525 Score = 39.7 bits (91), Expect = 0.027 Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1325 G VE+ G TW +CD WT + + VVC G R + F S P ++ Sbjct: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263 Query: 1326 DDVECSGTESTLWQCR 1341 D C+GTE+ + C+ Sbjct: 264 D---CTGTEAHISSCK 276 >gi|194018748 CD6 molecule [Homo sapiens] Length = 668 Score = 247 bits (630), Expect = 8e-65 Identities = 162/441 (36%), Positives = 208/441 (47%), Gaps = 59/441 (13%) Query: 459 GVICSAAHSWSTPSP-DTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517 G++ +A +P+P D L T + + L +RL NG C G VEV SW Sbjct: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 Query: 518 VCDDSWDTNDANVVCRQLGCGWA----MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSC 573 C WD+ A VCR LGCG A LAP L +GN S Sbjct: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPE---------LPPPPAAGNTS----- 114 Query: 574 PHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSS--HALQTCKGPESSLALRLVNG 631 ++ N + ++CS +W + + S A TC + ALRLV+G Sbjct: 115 -----VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCA---ENRALRLVDG 166 Query: 632 GDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD 691 G C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA A F G GPI D Sbjct: 167 GGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRD 226 Query: 692 DVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSES 751 V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 227 QVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W------------ 265 Query: 752 SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 811 RL G DRC+G+VEV ++G W TVCD W ++A V+C+ LGCG A+ P Sbjct: 266 ----RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321 Query: 812 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 871 SG + C+G E L +C S+ C S A V+CSAS+S S P S Sbjct: 322 L-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPAS 377 Query: 872 RASTAGSESTLALRLVNGGDR 892 T ES++ +++ N R Sbjct: 378 -VQTVTIESSVTVKIENKESR 397 Score = 240 bits (613), Expect = 8e-63 Identities = 162/439 (36%), Positives = 208/439 (47%), Gaps = 55/439 (12%) Query: 590 GVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGT 649 G++ +AL P+P P +S A P L +RL NG C G VEV SW Sbjct: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 Query: 650 VCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPNN 708 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 Query: 709 GWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAG--SESSLALRLVNGGDRCQG 766 ++ N ++CS A+ R + S A + ALRLV+GG C G Sbjct: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 Query: 767 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 826 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 Query: 827 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRL 886 E+YLW CP H CGH EDAG +CS QS W RL Sbjct: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RL 267 Query: 887 VNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPI 946 G DRC G+VEV ++G W TVCD W ++A V+C+ LGCG A+ P SG + Sbjct: 268 TGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRM 326 Query: 947 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPA-- 1004 C+G E L +C S+ C A V+CSA++S T +PA Sbjct: 327 YYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASV 378 Query: 1005 LTVGSESSLALRLVNGGDR 1023 TV ESS+ +++ N R Sbjct: 379 QTVTIESSVTVKIENKESR 397 Score = 238 bits (608), Expect = 3e-62 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%) Query: 86 STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145 S+ ES + E + L +RL NG C G VE+ SW C WD+ A VCR LGC Sbjct: 30 SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88 Query: 146 GWAMS---------------APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190 G A + A GN + + CSG E L + H Sbjct: 89 GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143 Query: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249 C G A V C+ + ALRLV+GG C GRVE+ Sbjct: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176 Query: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309 L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CSG E+Y Sbjct: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236 Query: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGG 369 LW CP H CGH EDAG +CS QS W RL G Sbjct: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271 Query: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429 DRC+G+VEV +RG W TVCD W S+A V+C+ LGCG A P SG + Sbjct: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329 Query: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485 C+G E L +C S+ C S A V+CSA+ H+ STP P ++ T+T+ Sbjct: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383 Query: 486 VGSESSLALRLVNGGDR 502 ESS+ +++ N R Sbjct: 384 ---ESSVTVKIENKESR 397 Score = 236 bits (602), Expect = 1e-61 Identities = 162/453 (35%), Positives = 203/453 (44%), Gaps = 83/453 (18%) Query: 330 GVICSAPQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 386 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 Query: 387 VCDDSWDTSDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 431 C WD+ A VCR LGCG A + A GN + + Sbjct: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 Query: 432 CSGYESYLWSCPHNGWLSHNCQ-HSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490 CSG E L + H C+ A V C+ Sbjct: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157 Query: 491 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG 550 + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F Sbjct: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 Query: 551 QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPS 610 G GPI D V CSG E+YLW CP H CGH EDAG +CS Q SW Sbjct: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ---------SW-- 265 Query: 611 SHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 670 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG Sbjct: 266 ----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309 Query: 671 WATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQS 730 A P SG + C+G E L +C S+ C A V+CSA++S Sbjct: 310 TAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRS 365 Query: 731 RSTPRPDTWPTSHASTAGSESSLALRLVNGGDR 763 P S T ESS+ +++ N R Sbjct: 366 LHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397 Score = 229 bits (585), Expect = 1e-59 Identities = 152/404 (37%), Positives = 197/404 (48%), Gaps = 55/404 (13%) Query: 722 GVICSAAQSRSTPRP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYQGSWGT 778 G++ +A +P P D TS A + E L +RL NG C G VEV + SW Sbjct: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 Query: 779 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPHN 837 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 Query: 838 GWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS---RASTAGSESTLALRLVNGGDRCR 894 ++ N + ++CS ++ R + S RA +E+ ALRLV+GG C Sbjct: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENR-ALRLVDGGGACA 171 Query: 895 GRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCS 954 GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CS Sbjct: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231 Query: 955 GHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLA 1014 G E+YLW CP H CGH EDAG +CS QS W Sbjct: 232 GAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------- 265 Query: 1015 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1074 RL G DRC G+VEV +RG W TVCD W ++A V+C+ LGCG A+ P S Sbjct: 266 -RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-S 323 Query: 1075 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1118 G + C+G E L +C + ++ C A V+CSA++ Sbjct: 324 GRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364 Score = 228 bits (580), Expect = 5e-59 Identities = 155/422 (36%), Positives = 188/422 (44%), Gaps = 86/422 (20%) Query: 232 LALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP------- 284 L +RL NG C G VEV SW C WD+ A VCR LGCG A +A Sbjct: 43 LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102 Query: 285 --------GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNC-GHSEDAGVICSA 335 GN + + CSG E L + H C A V C+ Sbjct: 103 ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHACRSDGRRARVTCA- 156 Query: 336 PQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395 + ALRLV+GG C GRVE+L G WG+VCDD+WD Sbjct: 157 -----------------------ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLE 193 Query: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455 DA+VVCRQLGCGWA A F G GPI D V CSG E+YLW CP H C H Sbjct: 194 DAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHK 252 Query: 456 EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSW 515 EDAG +CS SW RL G DRC+G+VEV +RG W Sbjct: 253 EDAGAVCSEHQSW--------------------------RLTGGADRCEGQVEVHFRGVW 286 Query: 516 GTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPH 575 TVCD W ++A V+C+ LGCG A+ P SG + C+G E L +C Sbjct: 287 NTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSW 342 Query: 576 NGWLSHNCGHSEDAGVICSA---LQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGG 632 S+ C S A V+CSA L L TP P S +QT ESS+ +++ N Sbjct: 343 RFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPAS------VQTVT-IESSVTVKIENKE 395 Query: 633 DR 634 R Sbjct: 396 SR 397 Score = 180 bits (456), Expect = 1e-44 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%) Query: 851 GVICSASQSRPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 907 G++ +A P+P+P D TS A + E L +RL NG C G VEV + SW Sbjct: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 Query: 908 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 966 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 Query: 967 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1026 ++ N ++CS A+ + + ++ V + ALRLV+GG C G Sbjct: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 Query: 1027 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1086 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 Query: 1087 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1124 E+YLW CP H CGH EDAG +CS Q N+ Sbjct: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291 Query: 1125 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1169 W+P+ S CG + G S S YY N + C W Sbjct: 292 SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342 Score = 117 bits (292), Expect = 1e-25 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 1259 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1318 R + L G CAGRVE+ G WG+VCDD+W +++A VVCRQLGCG AV AL +F Sbjct: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 Query: 1319 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 G GPI D V CSG E+ LW C H C H+EDAG +CS Sbjct: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260 Score = 66.6 bits (161), Expect = 2e-10 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%) Query: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1321 C G+VE++ G W TVCD W EA+V+C+ LGCG AV S G Y+ Sbjct: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328 Query: 1322 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1368 C+G E TL C R S+ C+ A V+CS ++LSTP Sbjct: 329 -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372 Score = 44.7 bits (104), Expect = 8e-04 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1310 +RL N +SS C+G VE+ +W C W + AE VCR LGCG A +A Sbjct: 45 VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 >gi|22547221 tolloid-like 1 [Homo sapiens] Length = 1013 Score = 151 bits (381), Expect = 6e-36 Identities = 114/393 (29%), Positives = 176/393 (44%), Gaps = 54/393 (13%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CG L ++G SSP +P YP+ C+W + V G +I L F+ + L C +DY+E Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408 Query: 1201 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF------P 1253 + DG S LLG+ C D ++ TS+ +RM I FRS ++ GF A Y + Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIRK 468 Query: 1254 SDATLRLVNLNSSYGL---CAGRV---EIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG-- 1305 ++ ++ N Y C ++ E YH G T Q E+ R C Sbjct: 469 NEGQIQSPNYPDDYRPMKECVWKITVSESYHVGL---------TFQSFEIE-RHDNCAYD 518 Query: 1306 ----RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHNCNHRED 1355 R ++ + G G +D+ T +TLW N+ F+ N ED Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIR--STSNTLWMKFVSDGTVNKAGFAANFFKEED 576 Query: 1356 AGVI-----CSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 1401 C L+T P L R + + +CGG L++ +G ++P +P Sbjct: 577 ECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPK 636 Query: 1402 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDG- 1458 YP N CVW + YR++V F +LEG C YDY+E++ G S L + C Sbjct: 637 EYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAE 696 Query: 1459 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYS 1491 TS N M I F SD++++++GF+A ++S Sbjct: 697 VPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS 729 Score = 91.3 bits (225), Expect = 8e-18 Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 1/114 (0%) Query: 1139 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198 + C + SG +SP++P YP+ +C WEI G+RI L FS ++E H C++D+ Sbjct: 772 AECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDH 831 Query: 1199 VEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1251 +E+FDG S +LG++C N ++ N+M + F SD S Q GF A +++ Sbjct: 832 LEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHST 885 Score = 82.4 bits (202), Expect = 4e-15 Identities = 38/110 (34%), Positives = 64/110 (58%), Gaps = 3/110 (2%) Query: 1383 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1440 C + PSG +SP +P YP+ +C W+I +R+ + F + ++E C YD++E Sbjct: 774 CEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 833 Query: 1441 VFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1489 VFDG SP++ R+C + ++ N M +RF+SD S+ R+GF+A + Sbjct: 834 VFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATH 883 Score = 74.3 bits (181), Expect = 1e-12 Identities = 41/111 (36%), Positives = 59/111 (53%), Gaps = 3/111 (2%) Query: 1382 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIF--RDVQLEGGCNYDYI 1439 +CG L + +G+ SSP +P YP+ C+W + V ++ + F D+ C YDYI Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407 Query: 1440 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1489 EV DG +R SPL+ R C D TS+ + M I F S + +GF A Y Sbjct: 408 EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458 Score = 61.2 bits (147), Expect = 9e-09 Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 7/123 (5%) Query: 1135 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1190 A S+ CGG L S S+ + YP C W + G R+ L F ++E Sbjct: 881 ATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEE 940 Query: 1191 HHNCSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1248 +C +DYVE+FDG ++++ LG+ C +I+ S + + IHF +D + GF Sbjct: 941 EADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIY-SIGDSVLIHFHTDDTINKKGFHIR 999 Query: 1249 YNS 1251 Y S Sbjct: 1000 YKS 1002 Score = 59.7 bits (143), Expect = 2e-08 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 7/124 (5%) Query: 1383 CGGFL---SQPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 1436 CGG L S+P +S + F NYP C W + + R+ + F+ +V+ E C Y Sbjct: 887 CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946 Query: 1437 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 1495 DY+E+FDG ++ + R C G S + + I F +D +I ++GF Y S Sbjct: 947 DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRYP 1006 Query: 1496 DSTN 1499 D+T+ Sbjct: 1007 DTTH 1010 >gi|6912724 tolloid-like 2 [Homo sapiens] Length = 1015 Score = 144 bits (364), Expect = 6e-34 Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CG L +G FS+P +P YP+ + CVW I V G +I L F+++ L C +DYVE Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410 Query: 1201 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1254 + DG + LLG+ C D + S+ +R+ + FRS + GF A Y + Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470 Query: 1255 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1305 DA ++ N Y C R+ + G G T Q E+ R C Sbjct: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523 Query: 1306 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1349 R +A G G +DV+ S LW N+ F+ N Sbjct: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581 Query: 1350 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 1403 C HR + S P L + + +CGGF+++ +G +SP +P Y Sbjct: 582 WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640 Query: 1404 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 1461 P N CVW + YR+++ F +LEG C YD++EV G + L R C Sbjct: 641 PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700 Query: 1462 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 1491 TS SN M + F SD+++++RGFRA ++S Sbjct: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731 Score = 94.0 bits (232), Expect = 1e-18 Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CGGF+ +GT +SP +P YP N CVW++ + YRI+L F +LE + C +D+VE Sbjct: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679 Query: 1201 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1259 + G + L G+ C ++T ++ TS N M + F+SD + GF A + S + Sbjct: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737 Query: 1260 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1311 G C + G++ C + + + E C++ GC +S++ Sbjct: 738 -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783 Score = 87.0 bits (214), Expect = 1e-16 Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%) Query: 1139 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198 + CGG + +G SP+YP Y + +CVW I V+ G+ + L F ++E H +C++DY Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521 Query: 1199 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1257 +E+ DG S L+G C + + SS NR+ + F SD S GF A + + + Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581 Query: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1317 +G C R + G++ CD + + + +C ++ CG ++ L Sbjct: 582 W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633 Query: 1318 SG 1319 G Sbjct: 634 PG 635 Score = 81.3 bits (199), Expect = 8e-15 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%) Query: 1329 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 1387 EC T S L +CRN W N + ++AG C + Sbjct: 746 ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780 Query: 1388 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 1445 S G +SP +P YP+ +C W+I +RV + F + ++E C YD++E++DGP Sbjct: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840 Query: 1446 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 1487 +P++ R C + T +S + M +RF SD S+ R+GF+A Sbjct: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883 Score = 80.1 bits (196), Expect = 2e-14 Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%) Query: 1139 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198 + C + GT +SP++P YP+ +C W I +G+R+ L F+ ++E H C++D+ Sbjct: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833 Query: 1199 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1251 +E++DG + + +LG+ C + T +S + M + F SD S Q GF A +++ Sbjct: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887 Score = 75.1 bits (183), Expect = 6e-13 Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%) Query: 1383 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 1436 CGG L Q +S + F NYP+ A+C W I ++ Y V + FR +V+ E C Y Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948 Query: 1437 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 1495 DY+E +DG S+P + R C G S+ + + IRF +D +I ++GF A Y S+ Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008 Query: 1496 DSTNL 1500 D+ ++ Sbjct: 1009 DALHM 1013 Score = 74.3 bits (181), Expect = 1e-12 Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%) Query: 1382 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1439 +CG L +G+FS+P +P YP+ + CVW I V ++ + F + L C YDY+ Sbjct: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409 Query: 1440 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 1496 EV DG +R +PL+ R C D S+ + + + F S +I +GF A Y ++ D Sbjct: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467 Score = 65.1 bits (157), Expect = 6e-10 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%) Query: 1138 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1193 S+ CGG L T S+ + YP+ A+C W I GY + L F ++E + Sbjct: 886 STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945 Query: 1194 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1251 C +DY+E +DG +S+ LG+ C +I+ S+ + + I FR+D + GF A Y S Sbjct: 946 CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004 >gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo sapiens] Length = 730 Score = 138 bits (348), Expect = 4e-32 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CG L ++G FSSP YP Y + CVW I V G +I L F++L L C +DYVE Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381 Query: 1201 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1257 + DG + L G+ C + S+ +R+ + FRS ++ GF A Y + Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441 Query: 1258 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1310 ++ N Y +C R+++ G G S+ I+ + R + Sbjct: 442 DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500 Query: 1311 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1357 + G G DD++ T S LW N+ F+ N C+ G Sbjct: 501 ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558 Query: 1358 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 1408 C L+T P L + + +CGGFL++ +G +SP +P YP N Sbjct: 559 --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616 Query: 1409 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 1465 C+W + YR+++ F + EG C YD++EV G S L + C + TS Sbjct: 617 CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676 Query: 1466 SSNFMSIRFISDHSITRRGFRAEYYS 1491 N M + F SD++++++GF+A ++S Sbjct: 677 QYNNMRVEFKSDNTVSKKGFKAHFFS 702 Score = 90.5 bits (223), Expect = 1e-17 Identities = 43/117 (36%), Positives = 65/117 (55%), Gaps = 1/117 (0%) Query: 1136 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1195 R + CGGFL +G+ +SP +P YP N C+W++ + YRI+L F + E + C Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645 Query: 1196 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1251 +D+VE+ G S L GK C + ++ TS YN M + F+SD + GF A + S Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702 Score = 77.8 bits (190), Expect = 9e-14 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%) Query: 1383 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1440 CGG + + G SP YP +Y + C+W I+V + V + F+ ++E C YDY+E Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494 Query: 1441 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 1493 V DG SS LI R C + S+S+ + ++F+SD SI + GF ++ S P Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554 Query: 1494 SNDSTNLLCL 1503 + CL Sbjct: 555 NRGGCEQRCL 564 Score = 65.5 bits (158), Expect = 5e-10 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Query: 1382 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1439 +CG L +G+FSSP YP Y + CVW I V ++ + F + L C YDY+ Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380 Query: 1440 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1489 EV DG +R +PL R C S+ + + + F S + +GF A Y Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431 >gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo sapiens] Length = 823 Score = 138 bits (348), Expect = 4e-32 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CG L ++G FSSP YP Y + CVW I V G +I L F++L L C +DYVE Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381 Query: 1201 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1257 + DG + L G+ C + S+ +R+ + FRS ++ GF A Y + Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441 Query: 1258 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1310 ++ N Y +C R+++ G G S+ I+ + R + Sbjct: 442 DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500 Query: 1311 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1357 + G G DD++ T S LW N+ F+ N C+ G Sbjct: 501 ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558 Query: 1358 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 1408 C L+T P L + + +CGGFL++ +G +SP +P YP N Sbjct: 559 --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616 Query: 1409 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 1465 C+W + YR+++ F + EG C YD++EV G S L + C + TS Sbjct: 617 CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676 Query: 1466 SSNFMSIRFISDHSITRRGFRAEYYS 1491 N M + F SD++++++GF+A ++S Sbjct: 677 QYNNMRVEFKSDNTVSKKGFKAHFFS 702 Score = 90.5 bits (223), Expect = 1e-17 Identities = 43/117 (36%), Positives = 65/117 (55%), Gaps = 1/117 (0%) Query: 1136 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1195 R + CGGFL +G+ +SP +P YP N C+W++ + YRI+L F + E + C Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645 Query: 1196 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1251 +D+VE+ G S L GK C + ++ TS YN M + F+SD + GF A + S Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702 Score = 77.8 bits (190), Expect = 9e-14 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%) Query: 1383 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1440 CGG + + G SP YP +Y + C+W I+V + V + F+ ++E C YDY+E Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494 Query: 1441 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 1493 V DG SS LI R C + S+S+ + ++F+SD SI + GF ++ S P Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554 Query: 1494 SNDSTNLLCL 1503 + CL Sbjct: 555 NRGGCEQRCL 564 Score = 65.5 bits (158), Expect = 5e-10 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Query: 1382 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1439 +CG L +G+FSSP YP Y + CVW I V ++ + F + L C YDY+ Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380 Query: 1440 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1489 EV DG +R +PL R C S+ + + + F S + +GF A Y Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431 >gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo sapiens] Length = 986 Score = 138 bits (348), Expect = 4e-32 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CG L ++G FSSP YP Y + CVW I V G +I L F++L L C +DYVE Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381 Query: 1201 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1257 + DG + L G+ C + S+ +R+ + FRS ++ GF A Y + Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441 Query: 1258 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1310 ++ N Y +C R+++ G G S+ I+ + R + Sbjct: 442 DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500 Query: 1311 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1357 + G G DD++ T S LW N+ F+ N C+ G Sbjct: 501 ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558 Query: 1358 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 1408 C L+T P L + + +CGGFL++ +G +SP +P YP N Sbjct: 559 --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616 Query: 1409 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 1465 C+W + YR+++ F + EG C YD++EV G S L + C + TS Sbjct: 617 CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676 Query: 1466 SSNFMSIRFISDHSITRRGFRAEYYS 1491 N M + F SD++++++GF+A ++S Sbjct: 677 QYNNMRVEFKSDNTVSKKGFKAHFFS 702 Score = 104 bits (260), Expect = 7e-22 Identities = 87/356 (24%), Positives = 144/356 (40%), Gaps = 87/356 (24%) Query: 1136 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1195 R + CGGFL +G+ +SP +P YP N C+W++ + YRI+L F + E + C Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645 Query: 1196 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPS 1254 +D+VE+ G S L GK C + ++ TS YN M + F+SD + GF A + S Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKD 705 Query: 1255 DATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA 1314 + + + G V + G++ C + + + + C++ GC V+ Sbjct: 706 ECS------KDNGGCQQDCVNTF--GSYECQCRSGFVLHDNKHDCKEAGCDHKVT----- 752 Query: 1315 YFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNI 1374 S SG IT S N + + C+ STP + + Sbjct: 753 ---STSGTIT----------------------SPNWPDKYPSKKECTWAISSTPGHRVKL 787 Query: 1375 TRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGC 1434 T D SQP +C +D Sbjct: 788 TFMEMDIE-----SQP-----------------ECAYD---------------------- 803 Query: 1435 NYDYIEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1489 ++EVFDG +P++ R C + ++ + M +RF SD+S+ R+GF+A + Sbjct: 804 ---HLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856 Score = 77.8 bits (190), Expect = 9e-14 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%) Query: 1383 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1440 CGG + + G SP YP +Y + C+W I+V + V + F+ ++E C YDY+E Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494 Query: 1441 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 1493 V DG SS LI R C + S+S+ + ++F+SD SI + GF ++ S P Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554 Query: 1494 SNDSTNLLCL 1503 + CL Sbjct: 555 NRGGCEQRCL 564 Score = 77.4 bits (189), Expect = 1e-13 Identities = 52/199 (26%), Positives = 89/199 (44%), Gaps = 15/199 (7%) Query: 1139 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198 + C + SGT +SP++P YP+ +C W I G+R+ L F + +E+ C++D+ Sbjct: 745 AGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDH 804 Query: 1199 VEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1257 +E+FDG + +LG+ C + + ++ +RM + F SD S Q GF A + + Sbjct: 805 LEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQV 864 Query: 1258 LRLVNLNSSYGLCAGRVEIYHGGT---WGTVCDDSWTIQ---EAEVVCRQLGCGRAVSAL 1311 V Y Y GG W V ++ + ++ + V + CG L Sbjct: 865 RADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMEL 924 Query: 1312 GNAYFGS--------GSGP 1322 + Y + GSGP Sbjct: 925 FDGYDSTAPRLGRYCGSGP 943 Score = 68.9 bits (167), Expect = 4e-11 Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 3/103 (2%) Query: 1398 FYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSSPLIARV 1455 F NYP C W I + Y V ++F+ +V+ E C YDY+E+FDG ++P + R Sbjct: 879 FGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRY 938 Query: 1456 C-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDS 1497 C G S+ + + ++F SD +IT++GF Y S+ D+ Sbjct: 939 CGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDT 981 Score = 65.5 bits (158), Expect = 5e-10 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Query: 1382 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1439 +CG L +G+FSSP YP Y + CVW I V ++ + F + L C YDY+ Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380 Query: 1440 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 1489 EV DG +R +PL R C S+ + + + F S + +GF A Y Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431 >gi|72384339 CUB domain containing protein 2 [Homo sapiens] Length = 449 Score = 136 bits (342), Expect = 2e-31 Identities = 115/377 (30%), Positives = 156/377 (41%), Gaps = 40/377 (10%) Query: 1129 PTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKL 1188 P A CGG L SG FSSP++P YP N +C W I V G + L F L Sbjct: 18 PGLQAQAMEGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDL 77 Query: 1189 EAHHNCSFDYVEIFDG-SLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFL 1246 E H CSFD++EI++G S + LLG+ C FTSS++ M++ F SD + GF Sbjct: 78 EYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFS 137 Query: 1247 AWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGR 1306 A Y L GL + + + W I+ A G Sbjct: 138 AGYQKDVCGGVLT--------GLSGVLTSPEYPNNYPNSMECHWVIRAA---------GP 180 Query: 1307 A-VSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1365 A V + + G+ T D V G RG H C ++ G+ L Sbjct: 181 AHVKLVFVDFQVEGNEECTYDYVAVLGGPGP-----TRG--HHYCGSTRPPTLVSLGHEL 233 Query: 1366 ST--PAPFLNITRPNTDY----SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNY 1419 + F R Y C G+FSSP YP +YPNN +C W I + Y Sbjct: 234 QVVFKSDFNIGGRGFKAYYFSGECQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGY 293 Query: 1420 RVTVIFRDVQLE------GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSI 1472 +V V F D+ LE C++D++ FDG +PL+ C TSS N + + Sbjct: 294 QVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLL 353 Query: 1473 RFISDHSITRRGFRAEY 1489 +D S TRRGF Y Sbjct: 354 LLHTDRSTTRRGFSVAY 370 Score = 75.1 bits (183), Expect = 6e-13 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 5/112 (4%) Query: 1383 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIE 1440 CGG L+ SG +SP YP NYPN+ +C W I V ++F D Q+EG C YDY+ Sbjct: 145 CGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVA 204 Query: 1441 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYYS 1491 V GP + C R + S + + + F SD +I RGF+A Y+S Sbjct: 205 VLGGPGPTRG--HHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFS 254 >gi|5031863 galectin 3 binding protein [Homo sapiens] Length = 585 Score = 134 bits (338), Expect = 6e-31 Identities = 73/150 (48%), Positives = 90/150 (60%), Gaps = 11/150 (7%) Query: 626 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 685 +RL +GG QGRVE+ YRG WGTVCD+ WD DA+VVCR LG AT A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 686 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHAS 745 GPI+LD+V+C+G E+ L C + GWL NC H DAGV+C+ ++RST H Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT-NETRST---------HTL 133 Query: 746 TAGSESSLALRLVNGGDR-CQGRVEVLYQG 774 E S AL + R C + V QG Sbjct: 134 DLSRELSEALGQIFDSQRGCDLSISVNVQG 163 Score = 134 bits (336), Expect = 1e-30 Identities = 60/101 (59%), Positives = 74/101 (73%) Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422 +RL +GG QGRVE+ YRG WGTVCD+ WD +DA+VVCR LG AT A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463 GPI+LD+V+C+G E+ L C GWL NC+H DAGV+C+ Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124 Score = 130 bits (327), Expect = 1e-29 Identities = 60/111 (54%), Positives = 75/111 (67%) Query: 1015 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1074 +RL +GG +GRVE+ YRG WGTVCD+ WD DA+VVCR LG A A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 1075 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTD 1125 GPI+LD+V+C+G E+ L C GWL NC H DAGV+C+ ++ T D Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLD 134 Score = 130 bits (326), Expect = 1e-29 Identities = 59/101 (58%), Positives = 71/101 (70%) Query: 494 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 553 +RL +GG QGRVE+ YRG WGTVCD+ WD DA+VVCR LG A A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 554 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594 GPI+LD+V+C+G E+ L C GWL NC H DAGV+C+ Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124 Score = 129 bits (325), Expect = 2e-29 Identities = 61/112 (54%), Positives = 78/112 (69%), Gaps = 1/112 (0%) Query: 755 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 814 +RL +GG QGRVE+ Y+G WGTVCD+ WD DA+VVCR LG A A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 815 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPD 866 GPI+LD+V+C+G E+ L C GWL NC H DAGV+C+ +++R T + D Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT-NETRSTHTLD 134 Score = 128 bits (322), Expect = 4e-29 Identities = 58/101 (57%), Positives = 71/101 (70%) Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293 +RL +GG +GRVE+ YRG WGTVCD+ WD DA+VVCR LG A A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 GPI+LD+V+C+G E+ L C GWL NC H DAGV+C+ Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124 Score = 127 bits (319), Expect = 1e-28 Identities = 57/101 (56%), Positives = 71/101 (70%) Query: 884 LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 943 +RL +GG +GRVE+ Y+G WGTVCD+ WD DA+VVCR LG A A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 944 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 984 GPI+LD+V+C+G E+ L C GWL NC H DAGV+C+ Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124 Score = 126 bits (316), Expect = 2e-28 Identities = 59/101 (58%), Positives = 69/101 (68%) Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161 +RL +G QGRVEI YRG WGTVCD+ WD DA+VVCR LG A A G A FGQGS Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202 GPI LD+V+C+G E+ L C GWL NC H DAGV+C+ Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124 Score = 123 bits (308), Expect = 2e-27 Identities = 53/96 (55%), Positives = 67/96 (69%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331 GRVEI++ G WGTVCD+ W + +A VVCR LG A ALG A FG GSGPI LD+V+C+ Sbjct: 35 GRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCT 94 Query: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1367 GTE++L C++ GW NC H DAGV+C+ ST Sbjct: 95 GTEASLADCKSLGWLKSNCRHERDAGVVCTNETRST 130 >gi|126091152 cubilin [Homo sapiens] Length = 3623 Score = 125 bits (314), Expect = 4e-28 Identities = 107/377 (28%), Positives = 162/377 (42%), Gaps = 54/377 (14%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CGG L A+G+FSSP +P YP N +C+W I + G I L + +E H C+FD +E Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLE 1450 Query: 1201 IFDGSLNSSLLLGKICN----DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1256 I+ G S + ++C + +S+ N + I F++D+S GF A + + Sbjct: 1451 IYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVT--- 1507 Query: 1257 TLRLVNLNSSYGLCAGRVEIYHG--------GTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1308 G C G + G + + D SW I+ R Sbjct: 1508 -----------GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIR----------VDRNH 1546 Query: 1309 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG-VICSGNHL-- 1365 L N + P + G ST+ + + C + A ++ SGN L Sbjct: 1547 RVLLN-FTDFDLEPQDSCIMAYDGLSSTMSR------LARTCGREQLANPIVSSGNSLFL 1599 Query: 1366 ---STPAPFLNITRPNTDYSCGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNY-R 1420 S P+ R +CGG + S D SSP +P NYPNN C W I+ Q Sbjct: 1600 RFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNH 1659 Query: 1421 VTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISD 1477 +T+ F +LE C D++E+ DG + +PL R C TS S+ +++RF+SD Sbjct: 1660 ITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSD 1719 Query: 1478 HSITRRGFRAEYYSSPS 1494 SI+ GF +S S Sbjct: 1720 SSISAGGFHTTVTASVS 1736 Score = 125 bits (313), Expect = 5e-28 Identities = 107/388 (27%), Positives = 168/388 (43%), Gaps = 82/388 (21%) Query: 1138 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1197 S+ CGG L +SGTF SP+YP Y ++++C W ++ + G L F + LE H NC+ D Sbjct: 1162 STGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLD 1221 Query: 1198 YVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1256 Y+ ++DG ++S LL ++C D + + SS + M I R+D Q GF A Y Sbjct: 1222 YLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR----QT 1277 Query: 1257 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQ----------------EAEVVC- 1299 +V +N +YG+ I + + +WTI+ E + C Sbjct: 1278 CENVVIVNQTYGILE---SIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCS 1334 Query: 1300 ----------RQLG--CGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFS 1347 RQ+G CG + G+ + D V G +Q + WF Sbjct: 1335 TDYLELYDGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGV---GRREKGFQMQ---WFV 1388 Query: 1348 HNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNA 1407 + C G LS + G F S P +P YP N Sbjct: 1389 YGC-----------GGELSG--------------ATGSFSS--------PGFPNRYPPNK 1415 Query: 1408 KCVWDIEVQ--NNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARG---- 1461 +C+W I ++ ++T+ DV+ CN+D +E++ GP SP IA++C Sbjct: 1416 ECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPM 1475 Query: 1462 SFTSSSNFMSIRFISDHSITRRGFRAEY 1489 +S+ N ++IRF +D SI RGF A + Sbjct: 1476 QVSSTGNELAIRFKTDLSINGRGFNASW 1503 Score = 124 bits (312), Expect = 6e-28 Identities = 102/368 (27%), Positives = 158/368 (42%), Gaps = 32/368 (8%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CG L ++GT SP +P YP+ C W I V + I+L F LE H+NC+ DY+E Sbjct: 932 CGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991 Query: 1201 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1259 ++D +S LG+ C + TSS N + + F +D GFL Y + S AT Sbjct: 992 VYD--TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI-SAATAC 1048 Query: 1260 LVNLNSSYG-LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF-- 1316 L + G + + W C T++ +++ A+GN Y Sbjct: 1049 LQDYTDDLGTFTSPNFPNNYPNNW--ECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDF 1106 Query: 1317 ------GSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAP 1370 G P+ L S T+ N+ W + + T + Sbjct: 1107 LEIRDGGYEKSPL-LGIFYGSNLPPTIISHSNKLWLKF------------KSDQIDTRSG 1153 Query: 1371 FLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQL 1430 F + + CGG L+ SG F SP YP Y ++++C W ++ + + F+D L Sbjct: 1154 F-SAYWDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHL 1212 Query: 1431 E--GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRA 1487 E C DY+ V+DGP +S L+ ++C D SS + M I+ +D RGF+A Sbjct: 1213 EHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKA 1272 Query: 1488 EYYSSPSN 1495 EY + N Sbjct: 1273 EYRQTCEN 1280 Score = 122 bits (307), Expect = 2e-27 Identities = 112/398 (28%), Positives = 169/398 (42%), Gaps = 71/398 (17%) Query: 1131 TTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1190 TT TA S+ CGG + A G F+SP YP YP N +CVW I + G R+ L F + +LE Sbjct: 1729 TTVTASVSA-CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLED 1787 Query: 1191 HHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSY--NRMTIHFRSDISFQNTGFLA- 1247 +CS D+VEI +G+ L+G+ C ++ + SS + + + F SD S TGF A Sbjct: 1788 SQDCSRDFVEIREGNATGH-LVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQAT 1846 Query: 1248 ---------------------WYNSFPSDATLR-LVNLNSSYGLCAGRVEIYHGGTWGTV 1285 W ++P ++ + VN+N+S+ + +E+ Sbjct: 1847 FMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCY 1906 Query: 1286 CDDSWTIQEAEVVCRQLG--CGRAVSALGNAYFGSGSGPITL---DDVECSGTESTLWQC 1340 D + R +G CG + F S +T D SG L Sbjct: 1907 YDKLRIYDGPSIHARLIGAYCGTQTES-----FSSTGNSLTFHFYSDSSISGKGFLL--- 1958 Query: 1341 RNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGD----FSS 1396 WF+ V L T AP +CGGFL +GD S Sbjct: 1959 ---EWFA----------VDAPDGVLPTIAP----------GACGGFLR--TGDAPVFLFS 1993 Query: 1397 PFYPGNYPNNAKCVWDIEV-QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARV 1455 P +P +Y N C W I+ + + ++ D++ C YD + + DG + +A + Sbjct: 1994 PGWPDSYSNRVDCTWLIQAPDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVL 2053 Query: 1456 CD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSS 1492 C G S+ +M IRF SD S+TR GF A ++ S Sbjct: 2054 CGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKS 2091 Score = 113 bits (283), Expect = 1e-24 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 58/396 (14%) Query: 1150 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1209 G +SP +P YP+N+ W + VN+ + ++ + +E NC +D + I+DG + Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHA 1920 Query: 1210 LLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLA-WYNSFPSDATLRLVNLNSSYG 1268 L+G C + F+S+ N +T HF SD S GFL W+ D L + + G Sbjct: 1921 RLIGAYCGTQTESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTI----APG 1976 Query: 1269 LCAG-------RVEIYHGG---TWGTVCDDSWTIQ------EAEVVCRQLGCGRAVSALG 1312 C G V ++ G ++ D +W IQ E ++ + R A Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDSTVELNILSLDIESHRTC-AYD 2035 Query: 1313 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL 1372 + G + G E R+ G + D+ V +G + S Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIP-GPIRSTGEYMF-IRFTSDSSVTRAGFNASFHK--- 2090 Query: 1373 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIF-RDVQLE 1431 SCGG+L G +SP YP YP+N C W + VQ+ + V F + Q+ Sbjct: 2091 ---------SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIP 2141 Query: 1432 GG---CNY-DYIEVFDGPYRSSPLI------ARVCDG-ARGSFTSSSNFMSIRFISDHSI 1480 G CN DY+ + +GP SP + C A + +S N M ++FISDHS Sbjct: 2142 NGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSN 2201 Query: 1481 TRRGFRAEYYSSP----------SNDSTNLLCLPNH 1506 +GF+ +Y + DS + PNH Sbjct: 2202 EGQGFKIKYEAKSLACGGNVYIHDADSAGYVTSPNH 2237 Score = 112 bits (279), Expect = 4e-24 Identities = 103/382 (26%), Positives = 161/382 (42%), Gaps = 60/382 (15%) Query: 1141 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYR-INLGFSNLKLEAHHNCSFDY 1198 CGG + +S T SSP +PA YPNN C W I+ I L F++ +LE C+ D+ Sbjct: 1620 CGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDF 1679 Query: 1199 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1257 VEI DG + L G+ C D TS + +T+ F SD S G F + T Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGG-------FHTTVT 1732 Query: 1258 LRLVNLNSSYGLCAGRV------EIYHGGT---WGTVCDD---------SWTIQEAEVVC 1299 + ++ + G +IY W V S+ +++++ Sbjct: 1733 ASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCS 1792 Query: 1300 R---QLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDA 1356 R ++ G A L Y G+ S P+ + TLW D Sbjct: 1793 RDFVEIREGNATGHLVGRYCGN-SFPLNYSSI----VGHTLW-----------VRFISDG 1836 Query: 1357 GVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQ 1416 SG+ A F+ I D G G +SPF+P NYP+N+ W + V Sbjct: 1837 ----SGSGTGFQATFMKIF--GNDNIVG-----THGKVASPFWPENYPHNSNYQWTVNVN 1885 Query: 1417 NNYRV--TVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRF 1474 ++ V ++ D++ C YD + ++DGP + LI C SF+S+ N ++ F Sbjct: 1886 ASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCGTQTESFSSTGNSLTFHF 1945 Query: 1475 ISDHSITRRGFRAEYYSSPSND 1496 SD SI+ +GF E+++ + D Sbjct: 1946 YSDSSISGKGFLLEWFAVDAPD 1967 Score = 106 bits (265), Expect = 2e-22 Identities = 103/398 (25%), Positives = 163/398 (40%), Gaps = 53/398 (13%) Query: 1123 TTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPA--YYPNNAKCVWEIEVNSGYRIN 1180 T W + T P CGG+L ++ TF+SP + Y N CVW I I+ Sbjct: 3139 TAKGWKMSFRQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIH 3198 Query: 1181 LGFSNLKLEA---HHNCSFDYVEIFDGSLNSSLLLGKICNDTRQI-FTSSYNRMTIHFRS 1236 L F+ LEA C +DYV+++DG ++ L G C T F SS N +T+ F S Sbjct: 3199 LTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFIS 3258 Query: 1237 DISFQNTGFLAWYNSFPS------DATLRLVNLNS--------SYGLCAGRVEI-YHGGT 1281 D++ + GF A Y +AT N++S + +C ++ H Sbjct: 3259 DLTLEREGFNATYTIMDMPCGGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQV 3318 Query: 1282 WGTVCDDSWTIQEAEVVCRQ--LGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ 1339 TV W +Q C Q L + GN+ F + V S + + Sbjct: 3319 KITV----WALQLTSQDCTQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVI 3374 Query: 1340 CRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFY 1399 + +GV+ + +S I N DY + G+ SP + Sbjct: 3375 FK--------------SGVVNRNSRMSFT---YQIADCNRDY------HKAFGNLRSPGW 3411 Query: 1400 PGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCD 1457 P NY N+ C + N+ +++ F + +E C D++EV +G +SPL+ + C Sbjct: 3412 PDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCG 3471 Query: 1458 G-ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPS 1494 S +N + +RF SD + RG+ + SSPS Sbjct: 3472 TLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPS 3509 Score = 104 bits (260), Expect = 7e-22 Identities = 109/416 (26%), Positives = 164/416 (39%), Gaps = 49/416 (11%) Query: 1102 HNCGHHEDAGVICSATQIN----STTTDWWHPTTTTTARPSSNCGGFLFY----ASGTFS 1153 H CG H + + S Q+ S ++ S CGG ++ ++G + Sbjct: 2174 HFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGNVYIHDADSAGYVT 2233 Query: 1154 SPSYPAYYPNNAKCVWEIEVNSGYRINLGFSN-LKLEAHHNCSFDYVEIFDGSLNSSLLL 1212 SP++P YP +A C+W + RI L F + +E NC+ +Y+E+ DG + + +L Sbjct: 2234 SPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPIL 2293 Query: 1213 GKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCA 1271 K C + SS M + FRSD S + GF A Y S C Sbjct: 2294 SKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY----------------SIAQCG 2337 Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCR-QLGCGRAVSALGNAYFGSGSGPITLDDVE- 1329 GRV G G V +I + R L C + L Y L + Sbjct: 2338 GRVP----GQSGVV----ESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSG 2389 Query: 1330 CSGTESTLWQCRNRG-WFSHNCNHREDAGVICSGNHL--------STPAPFLNITRPNTD 1380 C +W G C + + S N S A + ++ Sbjct: 2390 CEKDFVEIWDNHTSGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSM 2449 Query: 1381 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCNYDY 1438 CGG L G F+SP YP P+ C W I R+T++F +++L CN ++ Sbjct: 2450 EECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEH 2509 Query: 1439 IEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSS 1492 + VF+G +SP + ++C S SS N M + F +D S GF A Y SS Sbjct: 2510 VIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSS 2565 Score = 102 bits (255), Expect = 3e-21 Identities = 104/391 (26%), Positives = 141/391 (36%), Gaps = 57/391 (14%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CGG L G+ SP YP YP CVW + + + F L LE H +C+ DY+E Sbjct: 590 CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLE 649 Query: 1201 IFDGSLNSSLLLGKICNDTRQI----FTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1256 I DG L LLGK C T + T + R IHF SD + GF Y + PSD Sbjct: 650 IRDGPLYQDPLLGKFCT-TFSVPPLQTTGPFAR--IHFHSDSQISDQGFHITYLTSPSDL 706 Query: 1257 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV-------- 1308 C G G + +T V + G + Sbjct: 707 R------------CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVE 754 Query: 1309 ----SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNH 1364 S Y G L V +GT S + N W + DA V Sbjct: 755 LQCQSDSSQNYIEVRDGETLLGKVCGNGTISHIKSITNSVWI----RFKIDASV------ 804 Query: 1365 LSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVI 1424 A F R +CG L+ G SPF+P YP C W I + + + Sbjct: 805 --EKASF----RAVYQVACGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLN 857 Query: 1425 FR--DVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSF-TSSSNFMSIRFISDHSIT 1481 F ++ C DY+E+ SP + C SF TS NF+ + F+ S Sbjct: 858 FTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTE 917 Query: 1482 RRGFRAEYYSSP------SNDSTNLLCLPNH 1506 GF A++ + +ST + P H Sbjct: 918 NHGFMAKFSAEDLACGEILTESTGTIQSPGH 948 Score = 102 bits (255), Expect = 3e-21 Identities = 169/737 (22%), Positives = 264/737 (35%), Gaps = 134/737 (18%) Query: 865 PDTWPTS------RASTAGS--ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCD-DYWDT 915 PD+ TS R T GS S LR + + C G + QGS GT +Y + Sbjct: 2416 PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDL----QGSIGTFTSPNYPNP 2471 Query: 916 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 975 N +C W ++AP + ++ +++R + H S Sbjct: 2472 NPHGRICE-----WRITAPEGRRI-----TLMFNNLRLATHPSC---------------- 2505 Query: 976 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS 1035 + + ++ + +S S + N+ S +++ + G R G Y S Sbjct: 2506 NNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSS 2565 Query: 1036 WGTVCDDSW-DTNDANVVC----------RQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 1084 VC S +T + N R L C W +S P G S I +D Sbjct: 2566 EDAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQ---GNSSISIHFEDFYL 2622 Query: 1085 SGNESYLWSCPHKGWLTHNCGHHEDAGV--ICSATQ-----INSTTTDWWHPTTTTTAR- 1136 ++ + L G + + +C ++ + + W H T Sbjct: 2623 ESHQDCQFDV-----LEFRVGDADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEH 2677 Query: 1137 -------PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLE 1189 ++CGG SG +SP+YP Y + C +E G+ I L FS+ +E Sbjct: 2678 IGFHAKYSFTDCGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIE 2737 Query: 1190 AHHNCSFDYVEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1248 H C++D V + +G S ++G+ C N + S N++ + F SD S Q GF A Sbjct: 2738 PHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYAT 2797 Query: 1249 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAE------VVCRQL 1302 +N+ TL C G I+H GT+ W E Sbjct: 2798 WNT----QTLG----------CGG---IFHSDN-GTIRSPHWPQNFPENSRCSWTAITHK 2839 Query: 1303 GCGRAVSALGNAYFGSGSGPITLDDVEC-SGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 +S N SG G V+ +GTE ++ + C + VI Sbjct: 2840 SKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEV-----DKALLATGCGNVAPGPVITP 2894 Query: 1362 GNHLSTPAPFLNITRPNTDYS------CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 1415 N + A F + P +S CG + PSG SP YP Y NN C + IE Sbjct: 2895 SNTFT--AVFQSQEAPAQGFSASFVSRCGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEA 2952 Query: 1416 QNNYRVTVIFRDVQLE------GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNF 1469 V + F LE G C D + + G S A VC + + + Sbjct: 2953 NPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGP 3012 Query: 1470 MSIRFISDHSITRRGFRAEY----YSSPSNDSTNLLCLPNHMQA------------SVSR 1513 + + F S+ IT GF+ Y N S+ ++ P + A +VS Sbjct: 3013 VLLNFYSNEQITDFGFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSD 3072 Query: 1514 SYLQSLGFSASDLVIST 1530 + L FS D+V ST Sbjct: 3073 DKVIELKFSDFDVVPST 3089 Score = 99.8 bits (247), Expect = 2e-20 Identities = 99/383 (25%), Positives = 156/383 (40%), Gaps = 57/383 (14%) Query: 1138 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1197 + CGG SG SP+YP+ Y +N C W I V+ +R+ L F++ LE +C Sbjct: 1507 TGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMA 1566 Query: 1198 YVEIFDGSLNSSLLLGKICNDTRQI--FTSSYNRMTIHFRSDISFQNTGFLAWY------ 1249 Y DG ++ L + C + SS N + + F+S S QN GF A + Sbjct: 1567 Y----DGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGG 1622 Query: 1250 ----NSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQ---- 1301 +SF + ++ R + C+ ++ T+ + ++ + R Sbjct: 1623 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1682 Query: 1302 LGCGRAVSALGNAYFGSGSG-PITLDDVECSGTESTLWQCRNRGWFSHNCNHR--EDAGV 1358 L G + L Y G+ PIT FS R D+ + Sbjct: 1683 LDGGHEDAPLRGRYCGTDMPHPITS--------------------FSSALTLRFVSDSSI 1722 Query: 1359 ICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNN 1418 G H + A +CGG G F+SP YP YP N +CVW+I Sbjct: 1723 SAGGFHTTVTASVS---------ACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPG 1773 Query: 1419 YRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS--SNFMSIRF 1474 R+ + F QLE C+ D++E+ +G + L+ R C + SS + + +RF Sbjct: 1774 NRLQLSFISFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRF 1832 Query: 1475 ISDHSITRRGFRAEYYSSPSNDS 1497 ISD S + GF+A + ND+ Sbjct: 1833 ISDGSGSGTGFQATFMKIFGNDN 1855 Score = 98.6 bits (244), Expect = 5e-20 Identities = 107/435 (24%), Positives = 168/435 (38%), Gaps = 54/435 (12%) Query: 1120 NSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1179 +S +D T T+ CGG G P + + +CV+ ++ G +I Sbjct: 687 DSQISDQGFHITYLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQI 746 Query: 1180 NLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDI 1238 + F++++L+ + S +Y+E+ DG LLGK+C N T S N + I F+ D Sbjct: 747 QINFTHVELQCQSDSSQNYIEVRDGET----LLGKVCGNGTISHIKSITNSVWIRFKIDA 802 Query: 1239 SFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVV 1298 S + F A Y D + S + +Y G C WTI + + Sbjct: 803 SVEKASFRAVYQVACGDELTGEGVIRSPFF-----PNVYPGER---TC--RWTIHQPQ-- 850 Query: 1299 CRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGV 1358 V L F GS D G+ S L N+ + C + + Sbjct: 851 -------SQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY----CGTDIPSFI 899 Query: 1359 ICSGNHLSTPAPFLNITRPN--------TDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCV 1410 N L + T + D +CG L++ +G SP +P YP+ C Sbjct: 900 TSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCT 959 Query: 1411 WDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSS 1467 W I VQ N+ + ++F LE C DY+EV+D +S + R C S TSS Sbjct: 960 WHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSG 1017 Query: 1468 NFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLV 1527 N + + F++D + GF Y + S CL + Y LG S Sbjct: 1018 NSLMLVFVTDSDLAYEGFLINYEAI----SAATACL---------QDYTDDLGTFTSPNF 1064 Query: 1528 ISTWNGYYECRPQIT 1542 + + +EC +IT Sbjct: 1065 PNNYPNNWECIYRIT 1079 Score = 97.4 bits (241), Expect = 1e-19 Identities = 99/377 (26%), Positives = 153/377 (40%), Gaps = 51/377 (13%) Query: 1141 CGGFLFYASGT--FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198 CGGFL SP +P Y N C W I+ + L +L +E+H C++D Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESHRTCAYDS 2036 Query: 1199 VEIFDGSLNSSLLLGKICNDTRQI---FTSSYNRMTIHFRSDISFQNTGFLAWYN----- 1250 + I DG N + L +C R+I S+ M I F SD S GF A ++ Sbjct: 2037 LVIRDGDNNLAQQLAVLCG--REIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGG 2094 Query: 1251 ---------SFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQ 1301 + P NLN C+ V + G T + + I + C Q Sbjct: 2095 YLHADRGIITSPKYPETYPSNLN-----CSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQ 2149 Query: 1302 LGCGRAVSALGNAYFGSGSGPITLDDVEC-SGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360 V G GP + C S STL+ N+ + +H + Sbjct: 2150 --GDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEG---- 2203 Query: 1361 SGNHLSTPAPFLNITRPNTDYSCGGFL----SQPSGDFSSPFYPGNYPNNAKCVWDIEVQ 1416 G + A L +CGG + + +G +SP +P NYP +A C+W + Sbjct: 2204 QGFKIKYEAKSL---------ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAP 2254 Query: 1417 NNYRVTVIFR---DVQLEGGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSI 1472 R+ + F D+++ C +Y+E+ DG +P++++ C S SS M + Sbjct: 2255 PETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYL 2314 Query: 1473 RFISDHSITRRGFRAEY 1489 RF SD+S T GF+A+Y Sbjct: 2315 RFRSDNSPTHVGFKAKY 2331 Score = 91.7 bits (226), Expect = 6e-18 Identities = 97/386 (25%), Positives = 148/386 (38%), Gaps = 59/386 (15%) Query: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200 CG L G SP +P YP C W I I L F+ ++ + +C DYVE Sbjct: 817 CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875 Query: 1201 IFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1259 I S+ S K C D TS YN + + F S +N GF+A + Sbjct: 876 IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF---------- 925 Query: 1260 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA---EVVCRQLGCGRAVSALGNAYF 1316 S+ L G + + + + TIQ V + C + N Sbjct: 926 -----SAEDLACGEI----------LTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLI 970 Query: 1317 GSGSGPITLD-DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNIT 1375 L+ C+ ++ + C + SGN L + + Sbjct: 971 HLMFETFHLEFHYNCTNDYLEVYDTDSETSLGRYCGKSIPPSLTSSGNSL------MLVF 1024 Query: 1376 RPNTDYSCGGFL----------------SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNY 1419 ++D + GFL + G F+SP +P NYPNN +C++ I V+ Sbjct: 1025 VTDSDLAYEGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQ 1084 Query: 1420 RVTVIFRDVQLE---GGCNYDYIEVFDGPYRSSPLIARVCDGAR--GSFTSSSNFMSIRF 1474 + V F + LE G D++E+ DG Y SPL+ + G+ + S SN + ++F Sbjct: 1085 LIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLG-IFYGSNLPPTIISHSNKLWLKF 1143 Query: 1475 ISDHSITRRGFRAEYYSSPSNDSTNL 1500 SD TR GF A + S + NL Sbjct: 1144 KSDQIDTRSGFSAYWDGSSTGCGGNL 1169 Score = 86.7 bits (213), Expect = 2e-16 Identities = 87/372 (23%), Positives = 154/372 (41%), Gaps = 29/372 (7%) Query: 1137 PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF 1196 P CG L +G+FS S Y ++ C W I+ G + + F+ +LE+ NC Sbjct: 470 PQQVCGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529 Query: 1197 DYVEIFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGF-LAWYNSFPS 1254 ++++++DG +S+ LG+ C + SS N + H S+ GF + W P Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 589 Query: 1255 DATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV----SA 1310 + L YG + G + D W + + + G Sbjct: 590 CGGI----LTGPYGSIKSP---GYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDD 642 Query: 1311 LGNAYFGSGSGPITLDDVECS-GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPA 1369 Y GP+ D + T ++ + G F+ + D+ + G H++ Sbjct: 643 CNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFA-RIHFHSDSQISDQGFHIT--- 698 Query: 1370 PFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQ 1429 +T P +D CGG + P G+ P G + + +CV+ ++ ++ + F V+ Sbjct: 699 ---YLTSP-SDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVE 754 Query: 1430 L--EGGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFR 1486 L + + +YIEV DG L+ +VC +G S +N + IRF D S+ + FR Sbjct: 755 LQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFR 810 Query: 1487 AEYYSSPSNDST 1498 A Y + ++ T Sbjct: 811 AVYQVACGDELT 822 Score = 73.9 bits (180), Expect = 1e-12 Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 4/113 (3%) Query: 1383 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 1440 CGG L G F+SP YPG YPNN C W + VT+ F + ++ G C +Y+ Sbjct: 3511 CGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570 Query: 1441 VFDGPYRSSPLIARVCDG--ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYS 1491 ++DGP SSP C G + F +SSN + I+F +D++ FR + S Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTWDS 3623 Score = 71.6 bits (174), Expect = 6e-12 Identities = 45/115 (39%), Positives = 63/115 (54%), Gaps = 5/115 (4%) Query: 1140 NCGGFLFYASGTFSSPSYP-AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198 +CGG ++SG +SP+Y A YPN+ C++ I V+ I L FS+ + +CS DY Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095 Query: 1199 VEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF 1252 + I+DG+ S LLGK C R SS N M + F++D SFQ W SF Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTA--KGWKMSF 3147 Score = 71.2 bits (173), Expect = 8e-12 Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 5/132 (3%) Query: 1120 NSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1179 +S T+D + T++ S CGG L+ G+F+SP YP YPNN C W + +G + Sbjct: 3492 DSVTSDRGYEIIWTSS--PSGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLV 3549 Query: 1180 NLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQI--FTSSYNRMTIHFRSD 1237 + F + ++ +C +Y+ ++DG SS G C I F +S N++ I F +D Sbjct: 3550 TINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHAD 3609 Query: 1238 ISFQNTGF-LAW 1248 + + + F L W Sbjct: 3610 YARRPSAFRLTW 3621 Score = 63.9 bits (154), Expect = 1e-09 Identities = 35/112 (31%), Positives = 61/112 (54%), Gaps = 4/112 (3%) Query: 1382 SCGGFLSQPSGDFSSPFYP-GNYPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCNYDY 1438 SCGG + SG +SP Y +YPN+ C++ I V ++ + + F D + C++DY Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095 Query: 1439 IEVFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEY 1489 + ++DG S PL+ + C R + SS+N M + F +D T +G++ + Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSF 3147 Score = 56.6 bits (135), Expect = 2e-07 Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 11/206 (5%) Query: 1058 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP--HKGWLTHNCGHHEDAGVICS 1115 C W + +P + + + L C+ N L P H CG + A V Sbjct: 3306 CTWVIDSPPHQQVKITVWALQLTSQDCTQNYLQLQDSPQGHGNSRFQFCGRNASA-VPVF 3364 Query: 1116 ATQINSTTTDWWHPTTTTTARPS-----SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWE 1170 + +++ + +R S ++C A G SP +P Y N+ C Sbjct: 3365 YSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYHKAFGNLRSPGWPDNYDNDKDCTVT 3424 Query: 1171 IEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYN 1228 + + I+L F +L +E C D++E+ +GS ++S LLGK C +F S N Sbjct: 3425 LTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVF-SQNN 3483 Query: 1229 RMTIHFRSDISFQNTGFLAWYNSFPS 1254 + + F+SD + G+ + S PS Sbjct: 3484 ELYLRFKSDSVTSDRGYEIIWTSSPS 3509 Score = 51.2 bits (121), Expect = 9e-06 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 12/123 (9%) Query: 1140 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF--- 1196 +CGG+L G +SP YP YP+N C W + V SG I + F + + S Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150 Query: 1197 DYVEIFDGSLNSSLLL------GKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1248 DY+ + +G S L G C + +FTS N+M + F SD S + GF Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSD-NQMFVQFISDHSNEGQGFKIK 2209 Query: 1249 YNS 1251 Y + Sbjct: 2210 YEA 2212 Score = 41.2 bits (95), Expect = 0.009 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 8/108 (7%) Query: 1387 LSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYIEVFDG 1444 ++Q G S YP Y N C W I V F LE C+ DY+E++DG Sbjct: 1284 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1343 Query: 1445 PYRSSPLIARVC--DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 1490 P + + R C D T+SS + +GF+ +++ Sbjct: 1344 PRQ----MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWF 1387 >gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] Length = 782 Score = 122 bits (305), Expect = 4e-27 Identities = 63/113 (55%), Positives = 73/113 (64%), Gaps = 1/113 (0%) Query: 352 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411 AS A + + L G GRVEV G WGTVCDDSW+ S A VVCRQLG +A Sbjct: 664 ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723 Query: 412 APGNARFGQ-GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463 A A FGQ GS PI+LDDVRC+G+E L C HNG +HNC+H EDAGV+CS Sbjct: 724 AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776 Score = 118 bits (295), Expect = 6e-26 Identities = 62/113 (54%), Positives = 72/113 (63%), Gaps = 1/113 (0%) Query: 744 ASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 803 AS A + + L G GRVEV G WGTVCDDSW+ + A VVCRQLG +A+ Sbjct: 664 ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723 Query: 804 APGNARFGQ-GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 855 A A FGQ GS PI+LDDVRC+G E L C HNG +HNC H EDAGV+CS Sbjct: 724 AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776 Score = 117 bits (293), Expect = 1e-25 Identities = 57/91 (62%), Positives = 65/91 (71%), Gaps = 1/91 (1%) Query: 245 GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ-GSGPIVLDDVRC 303 GRVEV G WGTVCDD W+ + A VVCRQLG +A+ A A+FGQ GS PI+LDDVRC Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745 Query: 304 SGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 +G E L C HNG THNC H EDAGV+CS Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776 Score = 116 bits (290), Expect = 2e-25 Identities = 57/95 (60%), Positives = 65/95 (68%), Gaps = 1/95 (1%) Query: 113 GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQ-GSGPIALDDVRC 171 GRVE+ G WGTVCDDSW+ + A VVCRQLG +A+ A A FGQ GS PI LDDVRC Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745 Query: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQP 206 +G E L C HNG +HNC H EDAGV+CS P Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQNP 780 Score = 116 bits (290), Expect = 2e-25 Identities = 57/91 (62%), Positives = 65/91 (71%), Gaps = 1/91 (1%) Query: 505 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ-GSGPIVLDDVRC 563 GRVEV G WGTVCDDSW+ + A VVCRQLG +A+ A A FGQ GS PI+LDDVRC Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745 Query: 564 SGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594 +G E L C HNG +HNC H EDAGV+CS Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776 Score = 115 bits (289), Expect = 3e-25 Identities = 69/146 (47%), Positives = 82/146 (56%), Gaps = 16/146 (10%) Query: 855 SASQSRPTPSP---DTWPTSR------------ASTAGSESTLALRLVNGGDRCRGRVEV 899 +A+ PTP P P SR AS A + + L G GRVEV Sbjct: 631 TAAPPAPTPRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSGRVEV 690 Query: 900 LYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ-GSGPIVLDDVRCSGHES 958 G WGTVCDD W+ + A VVCRQLG +A+ A A+FGQ GS PI+LDDVRC+G E Sbjct: 691 FVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCAGWER 750 Query: 959 YLWSCPHNGWLSHNCGHHEDAGVICS 984 L C HNG +HNC H EDAGV+CS Sbjct: 751 NLLECQHNGVGTHNCEHDEDAGVVCS 776 Score = 115 bits (288), Expect = 4e-25 Identities = 67/138 (48%), Positives = 77/138 (55%), Gaps = 11/138 (7%) Query: 600 PTPIRPRSWPSSHA--------LQTCKGPESSLALRLVN--GGDRCQGRVEVLYRGSWGT 649 P P RP P S L + +RLV G GRVEV G WGT Sbjct: 639 PRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGT 698 Query: 650 VCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQ-GSGPIVLDDVRCSGHESYLWSCPNN 708 VCDDSW+ + A VVCRQLG +A A A FGQ GS PI+LDDVRC+G E L C +N Sbjct: 699 VCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHN 758 Query: 709 GWLSHNCGHHEDAGVICS 726 G +HNC H EDAGV+CS Sbjct: 759 GVGTHNCEHDEDAGVVCS 776 Score = 115 bits (288), Expect = 4e-25 Identities = 57/91 (62%), Positives = 64/91 (70%), Gaps = 1/91 (1%) Query: 1026 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ-GSGPIVLDDVRC 1084 GRVEV G WGTVCDDSW+ + A VVCRQLG +A+ A A FGQ GS PI+LDDVRC Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745 Query: 1085 SGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1115 +G E L C H G THNC H EDAGV+CS Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776 Score = 115 bits (287), Expect = 5e-25 Identities = 55/92 (59%), Positives = 65/92 (70%), Gaps = 1/92 (1%) Query: 1271 AGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-SGSGPITLDDVE 1329 +GRVE++ GG WGTVCDDSW I A VVCRQLG AV A+ A FG GS PI LDDV Sbjct: 685 SGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVR 744 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 C+G E L +C++ G +HNC H EDAGV+CS Sbjct: 745 CAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776 >gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] Length = 495 Score = 114 bits (285), Expect = 8e-25 Identities = 53/109 (48%), Positives = 67/109 (61%) Query: 747 AGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPG 806 +G E+ + +RLVNG +GRVEV + WGTVCDD WD D +VVCR LG Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444 Query: 807 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 855 ARFGQG+G I +DDV C G E ++ C + W NCGH+EDA V C+ Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 112 bits (281), Expect = 2e-24 Identities = 53/108 (49%), Positives = 66/108 (61%) Query: 487 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 546 G E+ + +RLVNG +GRVEV + WGTVCDD WD D +VVCR LG Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445 Query: 547 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594 ARFGQG+G I +DDV C G E ++ C + W NCGH+EDA V C+ Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 112 bits (280), Expect = 3e-24 Identities = 53/108 (49%), Positives = 63/108 (58%) Query: 1008 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 1067 G E+ + +RLVNG GRVEV + WGTVCDD WD D +VVCR LG Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445 Query: 1068 ARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1115 ARFGQG+G I +DDV C G E ++ C W NCGH EDA V C+ Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 112 bits (279), Expect = 4e-24 Identities = 52/110 (47%), Positives = 66/110 (60%) Query: 93 AEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 152 A G ++ + +RLVNG G +GRVE+ + WGTVCDD WD D +VVCR LG Sbjct: 384 ASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVY 443 Query: 153 GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202 A FGQG+G I +DDV C G E ++ C + W NCGH EDA V C+ Sbjct: 444 RTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 111 bits (278), Expect = 5e-24 Identities = 53/108 (49%), Positives = 65/108 (60%) Query: 619 GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 678 G E+ + +RLVNG +GRVEV + WGTVCDD WD D +VVCR LG Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445 Query: 679 ARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726 ARFGQG+G I +DDV C G E ++ C + W NCGH EDA V C+ Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 110 bits (276), Expect = 9e-24 Identities = 52/109 (47%), Positives = 66/109 (60%) Query: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414 +G E+ + +RLVNG +GRVEV + WGTVCDD WD D +VVCR LG Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444 Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463 ARFGQG+G I +DDV C G E ++ C + W NC H+EDA V C+ Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 110 bits (275), Expect = 1e-23 Identities = 52/108 (48%), Positives = 65/108 (60%) Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286 G E+ + +RLVNG GRVEV + WGTVCDD WD D +VVCR LG Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445 Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 A+FGQG+G I +DDV C G E ++ C + W NCGH+EDA V C+ Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 109 bits (273), Expect = 2e-23 Identities = 52/109 (47%), Positives = 65/109 (59%) Query: 876 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 935 +G E+ + +RLVNG GRVEV + WGTVCDD WD D +VVCR LG Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444 Query: 936 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 984 A+FGQG+G I +DDV C G E ++ C + W NCGH EDA V C+ Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 101 bits (252), Expect = 6e-21 Identities = 46/102 (45%), Positives = 59/102 (57%) Query: 1260 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1319 ++ L + G GRVE+YH WGTVCDD W ++ +VVCR LG A FG G Sbjct: 392 MIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQG 451 Query: 1320 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 +G I +DDV C GTE T+++C W NC H EDA V C+ Sbjct: 452 TGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 >gi|5803080 macrophage receptor with collagenous structure [Homo sapiens] Length = 520 Score = 110 bits (276), Expect = 9e-24 Identities = 55/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%) Query: 358 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNAR 417 E+S+++R+V +R GR EV Y G+WGT+CDD W SDA V CR LG + G A Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471 Query: 418 F--GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463 + G G+G I LD+V+C G ES LWSC N W H+C H EDAGV CS Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 110 bits (276), Expect = 9e-24 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%) Query: 489 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNAR 548 E+S+++R+V +R GR EV Y G+WGT+CDD W +DA V CR LG + G A Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLG-----YSKGRAL 471 Query: 549 F--GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594 + G G+G I LD+V+C G ES LWSC N W H+C H EDAGV CS Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 110 bits (274), Expect = 2e-23 Identities = 56/111 (50%), Positives = 70/111 (63%), Gaps = 9/111 (8%) Query: 226 EGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 285 E E+S+++R+V G RGR EV Y G+WGT+CDD W +DA V CR LG + G Sbjct: 416 ERGENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKG 468 Query: 286 NAQF--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 A + G G+G I LD+V+C G ES LWSC N W H+C H EDAGV CS Sbjct: 469 RALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 110 bits (274), Expect = 2e-23 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%) Query: 621 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNAR 680 E+S+++R+V +R GR EV Y G+WGT+CDD W +DA V CR LG + G A Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471 Query: 681 F--GQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726 + G G+G I LD+V+C G ES LWSC N W H+C H EDAGV CS Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 110 bits (274), Expect = 2e-23 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%) Query: 750 ESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 809 E+S+++R+V +R GR EV Y G+WGT+CDD W +DA V CR LG + G A Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471 Query: 810 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 855 + G G+G I LD+V+C G ES LWSC N W H+C H EDAGV CS Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 108 bits (270), Expect = 5e-23 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%) Query: 879 ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQ 938 E+++++R+V G RGR EV Y G+WGT+CDD W +DA V CR LG + G A Sbjct: 419 ENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471 Query: 939 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 984 + G G+G I LD+V+C G ES LWSC N W H+C H EDAGV CS Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 108 bits (269), Expect = 6e-23 Identities = 54/108 (50%), Positives = 68/108 (62%), Gaps = 9/108 (8%) Query: 1010 ESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 1069 E+S+++R+V G RGR EV Y G+WGT+CDD W +DA V CR LG + G A Sbjct: 419 ENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471 Query: 1070 F--GQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1115 + G G+G I LD+V+C G ES LWSC W H+C H EDAGV CS Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 107 bits (268), Expect = 8e-23 Identities = 48/92 (52%), Positives = 60/92 (65%), Gaps = 7/92 (7%) Query: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF--GSGSGPITLDDVE 1329 GR E+Y+ GTWGT+CDD W +A V CR LG + G A + G+G+G I LD+V+ Sbjct: 433 GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSK-----GRALYKVGAGTGQIWLDNVQ 487 Query: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 C GTESTLW C W H+C+H EDAGV CS Sbjct: 488 CRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 107 bits (267), Expect = 1e-22 Identities = 53/120 (44%), Positives = 71/120 (59%), Gaps = 9/120 (7%) Query: 85 ESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLG 144 E ++ E ++ +++R+V R GR E+ Y G+WGT+CDD W +DA V CR LG Sbjct: 407 EQGVKGEKGERGENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLG 464 Query: 145 CGWAMSAPGNAWF--GQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202 + G A + G G+G I LD+V+C G ES LWSC N W H+C H EDAGV CS Sbjct: 465 Y-----SKGRALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 >gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo sapiens] Length = 451 Score = 105 bits (262), Expect = 4e-22 Identities = 52/120 (43%), Positives = 67/120 (55%), Gaps = 4/120 (3%) Query: 740 PTSHASTAGSESSLA----LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQ 795 P GS ++L +RLV G +GRVE+L+ G WGT+CDD W+ VVCR Sbjct: 331 PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390 Query: 796 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 855 LG + A FGQG+GPI L++V C G ES + C W + C HSEDAGV C+ Sbjct: 391 LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 105 bits (261), Expect = 5e-22 Identities = 49/101 (48%), Positives = 61/101 (60%) Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161 +RLV G G +GRVEIL+ G WGT+CDD W+ VVCR LG + A FGQG+ Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409 Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202 GPI L++V C G ES + C W + C H EDAGV C+ Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 104 bits (260), Expect = 7e-22 Identities = 49/101 (48%), Positives = 60/101 (59%) Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293 +RLV G GRVE+L+ G WGT+CDD W+ VVCR LG + A FGQG+ Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409 Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334 GPI L++V C G ES + C W T C HSEDAGV C+ Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 104 bits (259), Expect = 9e-22 Identities = 60/149 (40%), Positives = 77/149 (51%), Gaps = 10/149 (6%) Query: 324 GHSEDAGVICSAPQSRPTPS-----PDTWPTSHASTAGSESSLA----LRLVNGGDRCQG 374 G D G I P SR P ++ P GS ++L +RLV G +G Sbjct: 303 GLKGDRGAI-GFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEG 361 Query: 375 RVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 434 RVE+L+ G WGT+CDD W+ VVCR LG + A FGQG+GPI L++V C G Sbjct: 362 RVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFG 421 Query: 435 YESYLWSCPHNGWLSHNCQHSEDAGVICS 463 ES + C W + C HSEDAGV C+ Sbjct: 422 RESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 104 bits (259), Expect = 9e-22 Identities = 52/120 (43%), Positives = 66/120 (55%), Gaps = 4/120 (3%) Query: 869 PTSRASTAGSESTLA----LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 924 P + GS +TL +RLV G GRVE+L+ G WGT+CDD W+ VVCR Sbjct: 331 PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390 Query: 925 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 984 LG + A FGQG+GPI L++V C G ES + C W + C H EDAGV C+ Sbjct: 391 LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 103 bits (258), Expect = 1e-21 Identities = 48/101 (47%), Positives = 60/101 (59%) Query: 1015 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1074 +RLV G GRVE+L+ G WGT+CDD W+ VVCR LG + A FGQG+ Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409 Query: 1075 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1115 GPI L++V C G ES + C + W T C H EDAGV C+ Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 103 bits (257), Expect = 1e-21 Identities = 48/101 (47%), Positives = 60/101 (59%) Query: 494 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 553 +RLV G +GRVE+L+ G WGT+CDD W+ VVCR LG A FGQG+ Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409 Query: 554 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594 GPI L++V C G ES + C W + C HSEDAGV C+ Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 102 bits (255), Expect = 3e-21 Identities = 47/101 (46%), Positives = 63/101 (62%) Query: 1261 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1320 V L G GRVEI H G WGT+CDD W ++ +VVCR LG + A+FG G+ Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409 Query: 1321 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 GPI L++V C G ES++ +C+ R W + C+H EDAGV C+ Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 102 bits (253), Expect = 4e-21 Identities = 47/101 (46%), Positives = 60/101 (59%) Query: 626 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 685 +RLV G +GRVE+L+ G WGT+CDD W+ VVCR LG + A FGQG+ Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409 Query: 686 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726 GPI L++V C G ES + C W + C H EDAGV C+ Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.450 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 81,740,133 Number of Sequences: 37866 Number of extensions: 4157692 Number of successful extensions: 12705 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 101 Number of HSP's successfully gapped in prelim test: 44 Number of HSP's that attempted gapping in prelim test: 10012 Number of HSP's gapped (non-prelim): 1240 length of query: 1788 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1671 effective length of database: 13,817,196 effective search space: 23088534516 effective search space used: 23088534516 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.