Guide to the Human Genome
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Name: BRCA2 Sequence: fasta or formatted (3418aa) NCBI GI: 119395734
Description:

breast cancer 2, early onset

Referenced in:

Major Disease Loci
DNases, Recombination, and DNA Repair
Mammary Tissues

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1        175           3
 C cysteine            2.2         76           1
 D aspartate           5.0        171           2
 E glutamate           8.6        293           3
 F phenylalanine       4.0        136           2
 G glycine             3.6        122           2
 H histidine           2.4         83           2
 I isoleucine          5.5        187           2
 K lysine              9.4        322           3
 L leucine             8.2        281           2
 M methionine          1.3         45           1
 N asparagine          6.7        230           3
 P proline             4.4        149           3
 Q glutamine           4.5        154           2
 R arginine            3.2        110           2
 S serine             11.1        381           3
 T threonine           6.4        220           3
 V valine              5.4        184           3
 W tryptophan          0.6         20           1
 Y tyrosine            2.3         79           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   breast cancer 2, early onset 
ANKRD12               0.004   ankyrin repeat domain 12 isoform 2 
ANKRD12               0.004   ankyrin repeat domain 12 isoform 1 
RB1CC1                0.003   Rb1-inducible coiled coil protein 1 isoform 2 [Homo...
RB1CC1                0.003   Rb1-inducible coiled coil protein 1 isoform 1 [Homo...
BOD1L                 0.003   biorientation of chromosomes in cell division 1-like...
CENPE                 0.003   centromere protein E 
AGBL2                 0.003   carboxypeptidase 2, cytosolic 
SGOL2                 0.003   shugoshin-like 2 isoform 2 
SGOL2                 0.003   shugoshin-like 2 isoform 1 
SGOL2                 0.003   shugoshin-like 2 isoform 3 
DSPP                  0.002   dentin sialophosphoprotein preproprotein 
ANKRD26               0.002   ankyrin repeat domain 26 
CCDC88A               0.002   coiled-coil domain containing 88A isoform 2 
CYLC1                 0.002   cylicin, basic protein of sperm head cytoskeleton 1...
DST                   0.002   dystonin isoform 1e precursor 
GOLGA3                0.002   Golgi autoantigen, golgin subfamily a, 3 
CCDC144A              0.002   coiled-coil domain containing 144A 
BRCA1                 0.002   breast cancer 1, early onset isoform 3 
BRCA1                 0.002   breast cancer 1, early onset isoform 1 
MYH10                 0.002   myosin, heavy polypeptide 10, non-muscle 
TRIP11                0.002   thyroid hormone receptor interactor 11 
COBLL1                0.002   COBL-like 1 
CCDC88A               0.002   coiled-coil domain containing 88A isoform 1 
KIF20B                0.002   M-phase phosphoprotein 1 
CENPJ                 0.002   centromere protein J 
HMMR                  0.002   hyaluronan-mediated motility receptor isoform a [Ho...
MOSPD2                0.002   motile sperm domain containing 2 
C14orf106             0.002   chromosome 14 open reading frame 106 
TEX15                 0.002   testis expressed 15 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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