BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23943900 transmembrane channel-like 8 [Homo sapiens] (726 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23943900 transmembrane channel-like 8 [Homo sapiens] 1476 0.0 gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 366 e-101 gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 363 e-100 gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 332 1e-90 gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 332 1e-90 gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 197 3e-50 gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 197 3e-50 gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 187 3e-47 gi|187608784 transmembrane channel-like 6 [Homo sapiens] 171 2e-42 gi|187608791 transmembrane channel-like 6 [Homo sapiens] 171 2e-42 gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 154 4e-37 gi|21071070 transmembrane channel-like 1 [Homo sapiens] 152 1e-36 gi|122937502 transmembrane channel-like 3 [Homo sapiens] 108 1e-23 gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 40 0.008 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 39 0.013 gi|56606142 complement component 1, q subcomponent-like 4 [Homo ... 39 0.017 gi|134244285 Notch homolog 3 [Homo sapiens] 38 0.029 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 38 0.038 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 37 0.050 gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 37 0.084 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 37 0.084 gi|195972903 zinc finger protein 385A isoform a [Homo sapiens] 37 0.084 gi|24308079 zinc finger protein 385A isoform c [Homo sapiens] 37 0.084 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 36 0.11 gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 36 0.11 gi|7662302 TBK1 binding protein 1 [Homo sapiens] 36 0.14 gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 35 0.19 gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens] 35 0.19 gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens] 35 0.19 gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens] 35 0.19 >gi|23943900 transmembrane channel-like 8 [Homo sapiens] Length = 726 Score = 1476 bits (3820), Expect = 0.0 Identities = 726/726 (100%), Positives = 726/726 (100%) Query: 1 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 60 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT Sbjct: 1 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 60 Query: 61 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 120 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN Sbjct: 61 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 120 Query: 121 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 180 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT Sbjct: 121 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 180 Query: 181 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 240 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA Sbjct: 181 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 240 Query: 241 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL 300 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL Sbjct: 241 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL 300 Query: 301 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ 360 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ Sbjct: 301 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ 360 Query: 361 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE 420 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE Sbjct: 361 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE 420 Query: 421 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA 480 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA Sbjct: 421 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA 480 Query: 481 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL 540 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL Sbjct: 481 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL 540 Query: 541 GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS 600 GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS Sbjct: 541 GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS 600 Query: 601 FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG 660 FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG Sbjct: 601 FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG 660 Query: 661 PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF 720 PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF Sbjct: 661 PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF 720 Query: 721 PSGAEL 726 PSGAEL Sbjct: 721 PSGAEL 726 >gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] Length = 723 Score = 366 bits (940), Expect = e-101 Identities = 220/638 (34%), Positives = 352/638 (55%), Gaps = 30/638 (4%) Query: 32 SGTPVRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLW 91 S +R + +KR + ++E W +W+R +R E A+ + L LW Sbjct: 86 SSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELW 145 Query: 92 EGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPG------P 145 + I G FGTGI+SYF+FLRFL+LLNL+ L+ VLLP++ + P Sbjct: 146 REDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIP 205 Query: 146 TLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPES--SSVYSIR 202 ++ QC S G++ F++ + +L+G F T LFYG Y + + Y + Sbjct: 206 FKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLP 265 Query: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262 LAYLLS +A L L ++R V+G + + + K+F+ WDFCI + A + Sbjct: 266 LAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADL 325 Query: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322 K + E + +LEE R Q + ++T +T L +N + ++ AI+ AT Sbjct: 326 KHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATV 385 Query: 323 YSQDNKE---------ESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT 373 +SQ++ + E+LF+L YLP VI L NF+ P++F +++ E+Y P E+ LT Sbjct: 386 FSQEHMKKEIDKMVFGENLFIL--YLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLT 443 Query: 374 LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF 433 ++ CV ++LA++ + +LG I D +C+ GYN Y CWE VG+E+YKL IF Sbjct: 444 ILRCVFMRLATICVLVFTLGSKITSC--DDDTCDLCGYNQKLYPCWETQVGQEMYKLMIF 501 Query: 434 NFLLTVAFAFLVTLPRRLLVDRFSG----RFWAWLEREEFLVPKNVLDIVAGQTVTWMGL 489 +F++ +A V PR+LLV S + W ++EF +P NVL IV GQT+ W+G Sbjct: 502 DFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWG---QQEFAIPDNVLGIVYGQTICWIGA 558 Query: 490 FYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPL 549 F+ PLLP + ++ + FY+K+++LL R S RPFRAS+S FFF LVLL+GL LA +PL Sbjct: 559 FFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPL 618 Query: 550 GYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSL 609 +S I SS CG FTN++ W+V+P+ V+ P Q +H + S AF+ P +++ L Sbjct: 619 TISISRIPSSKACGPFTNFNTTWEVIPKTVST-FPSSLQSFIHGVTSEAFAVPFFMIICL 677 Query: 610 VLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLS 647 ++ ++ A+ R + +LR+QL + ++K +L++ L+ Sbjct: 678 IMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLT 715 >gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] Length = 613 Score = 363 bits (932), Expect = e-100 Identities = 215/607 (35%), Positives = 341/607 (56%), Gaps = 30/607 (4%) Query: 63 WQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLL 122 W +W+R +R E A+ + L LW + I G FGTGI+SYF+FLRFL+LLNL+ Sbjct: 7 WDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLV 66 Query: 123 SLLLTASFVLLPLVWLRPPDPG------PTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTG 176 L+ VLLP++ + P ++ QC S G++ F++ + +L+G Sbjct: 67 IFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSG 126 Query: 177 RAFTN-TYLFYGAYRVGPES--SSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTL 233 F T LFYG Y + + Y + LAYLLS +A L L ++R V+G + Sbjct: 127 TGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLI 186 Query: 234 LGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTA 293 + + K+F+ WDFCI + A +K + E + +LEE R Q + ++T +T Sbjct: 187 RSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETI 246 Query: 294 CRLLSYLRVNVLNGLLVVGAISAIFWATKYSQDNKE---------ESLFLLLQYLPPGVI 344 L +N + ++ AI+ AT +SQ++ + E+LF+L YLP VI Sbjct: 247 RIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFIL--YLPSIVI 304 Query: 345 ALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKS 404 L NF+ P++F +++ E+Y P E+ LT++ CV ++LA++ + +LG I D Sbjct: 305 TLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSC--DDD 362 Query: 405 SCESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSG----RF 460 +C+ GYN Y CWE VG+E+YKL IF+F++ +A V PR+LLV S + Sbjct: 363 TCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQC 422 Query: 461 WAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRA 520 W ++EF +P NVL IV GQT+ W+G F+ PLLP + ++ + FY+K+++LL R Sbjct: 423 WG---QQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRP 479 Query: 521 SSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVA 580 S RPFRAS+S FFF LVLL+GL LA +PL +S I SS CG FTN++ W+V+P+ V+ Sbjct: 480 SPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVS 539 Query: 581 LGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKW 640 P Q +H + S AF+ P +++ L++ ++ A+ R + +LR+QL + ++K Sbjct: 540 T-FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKC 598 Query: 641 HLVEDLS 647 +L++ L+ Sbjct: 599 YLIQKLT 605 >gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] Length = 706 Score = 332 bits (850), Expect = 1e-90 Identities = 225/626 (35%), Positives = 322/626 (51%), Gaps = 40/626 (6%) Query: 35 PVRGLPYAMMDKRLIWQLREP-------AGVQTLRWQRWQRRRQTVERRLREAAQRLARG 87 P R LP+ M +R Q +G +T RW R + RR +E + R Sbjct: 83 PSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR-------LLRRSKEKTKEGLRS 135 Query: 88 LGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPT- 146 L W L IGG FG G SYF+ LRFLLLLN+L+ +L A LLP WL PGP Sbjct: 136 LQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLP-TWLGGAPPGPPG 194 Query: 147 LNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPESSSVYSIRLAY 205 +++ C G++ F QL+++L+G + + LFYG Y P + + Y Sbjct: 195 PDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRPR------LAVTY 248 Query: 206 LLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKH 265 L A L+C L R V GL Q L S +VFS+WDF + +++ Sbjct: 249 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 308 Query: 266 EISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISA----IFWAT 321 I E KVELEE ++++Q +T + V VL LLVV + A ++WAT Sbjct: 309 IILYELKVELEE----TVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWAT 364 Query: 322 KYSQDNKEESLF-------LLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTL 374 + + +E L L + YLP IA VNF+ P +F + LE Y + ++ L Sbjct: 365 GCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFIL 424 Query: 375 IWCVVLKLASLGMFSVSLGQTILCIGRDKSS-CESYGYNVCDYQCWENSVGEELYKLSIF 433 + V L+LASL + SL I C G ++ C++ GYN CWE +G+E+YKL +F Sbjct: 425 LRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLF 484 Query: 434 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP 493 + L +A A L+ PR+LL G +EF VP VL ++ QTV W+G F+CP Sbjct: 485 DLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCP 544 Query: 494 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV 553 LLPLLN+V L FY+KK TL ++R FRAS++ FFF LVLLLGL +++VPL Y + Sbjct: 545 LLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSI 604 Query: 554 SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV 613 I S CG F S+ W +PE ++ LP Q L +LG+ AF+ PLL++ S+++ Sbjct: 605 FLIPPSKLCGPFRGQSSIWAQIPESIS-SLPETTQNFLFFLGTQAFAVPLLLISSILMAY 663 Query: 614 CVSQTQANARAIHRLRKQLVWQVQEK 639 V+ + R I L++Q + Q K Sbjct: 664 TVALANSYGRLISELKRQRQTEAQNK 689 >gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] Length = 712 Score = 332 bits (850), Expect = 1e-90 Identities = 225/626 (35%), Positives = 322/626 (51%), Gaps = 40/626 (6%) Query: 35 PVRGLPYAMMDKRLIWQLREP-------AGVQTLRWQRWQRRRQTVERRLREAAQRLARG 87 P R LP+ M +R Q +G +T RW R + RR +E + R Sbjct: 89 PSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR-------LLRRSKEKTKEGLRS 141 Query: 88 LGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPT- 146 L W L IGG FG G SYF+ LRFLLLLN+L+ +L A LLP WL PGP Sbjct: 142 LQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLP-TWLGGAPPGPPG 200 Query: 147 LNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPESSSVYSIRLAY 205 +++ C G++ F QL+++L+G + + LFYG Y P + + Y Sbjct: 201 PDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRPR------LAVTY 254 Query: 206 LLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKH 265 L A L+C L R V GL Q L S +VFS+WDF + +++ Sbjct: 255 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 314 Query: 266 EISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISA----IFWAT 321 I E KVELEE ++++Q +T + V VL LLVV + A ++WAT Sbjct: 315 IILYELKVELEE----TVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWAT 370 Query: 322 KYSQDNKEESLF-------LLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTL 374 + + +E L L + YLP IA VNF+ P +F + LE Y + ++ L Sbjct: 371 GCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFIL 430 Query: 375 IWCVVLKLASLGMFSVSLGQTILCIGRDKSS-CESYGYNVCDYQCWENSVGEELYKLSIF 433 + V L+LASL + SL I C G ++ C++ GYN CWE +G+E+YKL +F Sbjct: 431 LRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLF 490 Query: 434 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP 493 + L +A A L+ PR+LL G +EF VP VL ++ QTV W+G F+CP Sbjct: 491 DLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCP 550 Query: 494 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV 553 LLPLLN+V L FY+KK TL ++R FRAS++ FFF LVLLLGL +++VPL Y + Sbjct: 551 LLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSI 610 Query: 554 SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV 613 I S CG F S+ W +PE ++ LP Q L +LG+ AF+ PLL++ S+++ Sbjct: 611 FLIPPSKLCGPFRGQSSIWAQIPESIS-SLPETTQNFLFFLGTQAFAVPLLLISSILMAY 669 Query: 614 CVSQTQANARAIHRLRKQLVWQVQEK 639 V+ + R I L++Q + Q K Sbjct: 670 TVALANSYGRLISELKRQRQTEAQNK 695 >gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] Length = 1006 Score = 197 bits (501), Expect = 3e-50 Identities = 153/591 (25%), Positives = 274/591 (46%), Gaps = 64/591 (10%) Query: 75 RRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP 134 RR + + + + LW+ L IGG FGT + SYF FLR+LL N+ S +L SF+++P Sbjct: 415 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 474 Query: 135 LVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGP- 193 + + TLQ G L F + + F +T ++YG Y Sbjct: 475 QFTVAKKN-------TLQFTG--------LEFFTGVGY------FRDTVMYYGFYTNSTI 513 Query: 194 ---ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSW 250 S + Y+++LAY+ + ACL CF L M K + Y ++ +F W Sbjct: 514 QHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572 Query: 251 DFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLV 310 DF + ++A +K+ +S E + L E R Q + T Q R +Y+ V++ + Sbjct: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELR--QENSKLTFNQLLTRFSAYMVAWVVSTGVA 630 Query: 311 VGAISAIFWATKYSQD----NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYP- 365 + +A+++ +Y+ + + LLL P V++ +N P +++ +E Y Sbjct: 631 IACCAAVYYLAEYNLEFLKTHSNPGAVLLL----PFVVSCINLAVPCIYSMFRLVERYEM 686 Query: 366 PNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGE 425 P EV + LI + LK++ +G+ T+ G + CWE +G+ Sbjct: 687 PRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE---------------CWETLIGQ 731 Query: 426 ELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVT 485 ++Y+L + +F+ ++ +FL RR++ + L +EF + +NVL+++ QT+ Sbjct: 732 DIYRLLLMDFVFSLVNSFLGEFLRRII----GMQLITSLGLQEFDIARNVLELIYAQTLV 787 Query: 486 WMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS-STFFFQLVLLLGLLL 544 W+G+F+CPLLP + + LF+ FY K +L+ N + S+ +RAS TFF L+ Sbjct: 788 WIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTG 847 Query: 545 AAVPLGYVVSSIHSSWDCG------LFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHA 598 L + + S DCG LF + W + G + + +GS Sbjct: 848 VLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSW-IDTLSTRPGYLWVVWIYRNLIGSVH 906 Query: 599 FSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRL 649 F F L +++ ++ + T+ I L +Q++ + ++K L+E L +L Sbjct: 907 FFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKL 957 >gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] Length = 760 Score = 197 bits (501), Expect = 3e-50 Identities = 153/591 (25%), Positives = 274/591 (46%), Gaps = 64/591 (10%) Query: 75 RRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP 134 RR + + + + LW+ L IGG FGT + SYF FLR+LL N+ S +L SF+++P Sbjct: 169 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 228 Query: 135 LVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGP- 193 + + TLQ G L F + + F +T ++YG Y Sbjct: 229 QFTVAKKN-------TLQFTG--------LEFFTGVGY------FRDTVMYYGFYTNSTI 267 Query: 194 ---ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSW 250 S + Y+++LAY+ + ACL CF L M K + Y ++ +F W Sbjct: 268 QHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 326 Query: 251 DFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLV 310 DF + ++A +K+ +S E + L E R Q + T Q R +Y+ V++ + Sbjct: 327 DFTVTHEKAVKLKQKNLSTEIRENLSELR--QENSKLTFNQLLTRFSAYMVAWVVSTGVA 384 Query: 311 VGAISAIFWATKYSQD----NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYP- 365 + +A+++ +Y+ + + LLL P V++ +N P +++ +E Y Sbjct: 385 IACCAAVYYLAEYNLEFLKTHSNPGAVLLL----PFVVSCINLAVPCIYSMFRLVERYEM 440 Query: 366 PNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGE 425 P EV + LI + LK++ +G+ T+ G + CWE +G+ Sbjct: 441 PRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE---------------CWETLIGQ 485 Query: 426 ELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVT 485 ++Y+L + +F+ ++ +FL RR++ + L +EF + +NVL+++ QT+ Sbjct: 486 DIYRLLLMDFVFSLVNSFLGEFLRRII----GMQLITSLGLQEFDIARNVLELIYAQTLV 541 Query: 486 WMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS-STFFFQLVLLLGLLL 544 W+G+F+CPLLP + + LF+ FY K +L+ N + S+ +RAS TFF L+ Sbjct: 542 WIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTG 601 Query: 545 AAVPLGYVVSSIHSSWDCG------LFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHA 598 L + + S DCG LF + W + G + + +GS Sbjct: 602 VLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSW-IDTLSTRPGYLWVVWIYRNLIGSVH 660 Query: 599 FSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRL 649 F F L +++ ++ + T+ I L +Q++ + ++K L+E L +L Sbjct: 661 FFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKL 711 >gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] Length = 948 Score = 187 bits (475), Expect = 3e-47 Identities = 129/473 (27%), Positives = 228/473 (48%), Gaps = 56/473 (11%) Query: 75 RRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP 134 RR + + + + LW+ L IGG FGT + SYF FLR+LL N+ S +L SF+++P Sbjct: 415 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 474 Query: 135 LVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGP- 193 + + TLQ G L F + + F +T ++YG Y Sbjct: 475 QFTVAKKN-------TLQFTG--------LEFFTGVGY------FRDTVMYYGFYTNSTI 513 Query: 194 ---ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSW 250 S + Y+++LAY+ + ACL CF L M K + Y ++ +F W Sbjct: 514 QHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572 Query: 251 DFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLV 310 DF + ++A +K+ +S E + L E R Q + T Q R +Y+ V++ + Sbjct: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELR--QENSKLTFNQLLTRFSAYMVAWVVSTGVA 630 Query: 311 VGAISAIFWATKYSQD----NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYP- 365 + +A+++ +Y+ + + LLL P V++ +N P +++ +E Y Sbjct: 631 IACCAAVYYLAEYNLEFLKTHSNPGAVLLL----PFVVSCINLAVPCIYSMFRLVERYEM 686 Query: 366 PNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGE 425 P EV + LI + LK++ +G+ T+ G + CWE +G+ Sbjct: 687 PRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE---------------CWETLIGQ 731 Query: 426 ELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVT 485 ++Y+L + +F+ ++ +FL RR++ + L +EF + +NVL+++ QT+ Sbjct: 732 DIYRLLLMDFVFSLVNSFLGEFLRRII----GMQLITSLGLQEFDIARNVLELIYAQTLV 787 Query: 486 WMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVL 538 W+G+F+CPLLP + + LF+ FY K +L+ N + S+ +RAS FF +L Sbjct: 788 WIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL 840 >gi|187608784 transmembrane channel-like 6 [Homo sapiens] Length = 805 Score = 171 bits (434), Expect = 2e-42 Identities = 190/670 (28%), Positives = 293/670 (43%), Gaps = 122/670 (18%) Query: 36 VRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVE--RRLREAAQRLARGLGL--- 90 +RG+P ++ +KR LRE + +W+ RLR A LGL Sbjct: 165 LRGMPLSLAEKR---SLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALL 221 Query: 91 --------WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPD 142 W AL IGG FG+ + SYF FL+ LL N L LLL +F++ P V P Sbjct: 222 SALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPAL 281 Query: 143 PGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRA-FTNTYLFYGAY------------ 189 PGP C G +LTG FT+T ++YG Y Sbjct: 282 PGPAP----VCTGLE---------------LLTGAGCFTHTVMYYGHYSNATLNQPCGSP 322 Query: 190 --------RVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAP 241 RVG Y++ LAYL S + C TL V + G+ Y+ Sbjct: 323 LDGSQCTPRVG---GLPYNMPLAYL-STVGVSFFITCITL---VYSMAHS--FGESYRVG 373 Query: 242 LSA-----KVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRL 296 ++ VF SWD+ + + A+ +++ I K L E Q + ++ C Sbjct: 374 STSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAE------WQLRHSPRSVCGR 427 Query: 297 LSYLRVNVLNGLLVVG-----AISAIFWATKYSQDNK---EESLFLLLQYLPPGVIALVN 348 L V L LL +G A++ ++ Q + +E++ L+L P V+ L+N Sbjct: 428 LRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVL----PLVVGLLN 483 Query: 349 FLGPLLFTFLVQLENYP-PNTEVNLTLIWCVVLKLASLGMFSVS-LGQTILCIGRDKSSC 406 P L L LE + P EV + + ++LKLA LG LG+ + Sbjct: 484 LGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRV---------- 533 Query: 407 ESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLER 466 V QCWE+ VG+ELY+ + +F+L + L R++ ++ R + Sbjct: 534 -----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKR----RRK 584 Query: 467 EEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFR 526 EF + +NVL+++ GQT+TW+G+ + PLLP + + L L FY+KK +LL N +A RP+ Sbjct: 585 PEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWL 644 Query: 527 AS-SSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLF----TNYSAPWQVVPELVAL 581 AS ST F L+ L AAV L Y V + S CG F T Y A V L A Sbjct: 645 ASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAA 704 Query: 582 G-----LPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQV 636 G LP + + + + + F F + +L V+ + + + + I L++Q+ + Sbjct: 705 GPRVSWLPWVHR---YLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEG 761 Query: 637 QEKWHLVEDL 646 ++K L+ L Sbjct: 762 EDKIFLINKL 771 >gi|187608791 transmembrane channel-like 6 [Homo sapiens] Length = 805 Score = 171 bits (434), Expect = 2e-42 Identities = 190/670 (28%), Positives = 293/670 (43%), Gaps = 122/670 (18%) Query: 36 VRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVE--RRLREAAQRLARGLGL--- 90 +RG+P ++ +KR LRE + +W+ RLR A LGL Sbjct: 165 LRGMPLSLAEKR---SLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALL 221 Query: 91 --------WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPD 142 W AL IGG FG+ + SYF FL+ LL N L LLL +F++ P V P Sbjct: 222 SALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPAL 281 Query: 143 PGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRA-FTNTYLFYGAY------------ 189 PGP C G +LTG FT+T ++YG Y Sbjct: 282 PGPAP----VCTGLE---------------LLTGAGCFTHTVMYYGHYSNATLNQPCGSP 322 Query: 190 --------RVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAP 241 RVG Y++ LAYL S + C TL V + G+ Y+ Sbjct: 323 LDGSQCTPRVG---GLPYNMPLAYL-STVGVSFFITCITL---VYSMAHS--FGESYRVG 373 Query: 242 LSA-----KVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRL 296 ++ VF SWD+ + + A+ +++ I K L E Q + ++ C Sbjct: 374 STSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAE------WQLRHSPRSVCGR 427 Query: 297 LSYLRVNVLNGLLVVG-----AISAIFWATKYSQDNK---EESLFLLLQYLPPGVIALVN 348 L V L LL +G A++ ++ Q + +E++ L+L P V+ L+N Sbjct: 428 LRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVL----PLVVGLLN 483 Query: 349 FLGPLLFTFLVQLENYP-PNTEVNLTLIWCVVLKLASLGMFSVS-LGQTILCIGRDKSSC 406 P L L LE + P EV + + ++LKLA LG LG+ + Sbjct: 484 LGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRV---------- 533 Query: 407 ESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLER 466 V QCWE+ VG+ELY+ + +F+L + L R++ ++ R + Sbjct: 534 -----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKR----RRK 584 Query: 467 EEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFR 526 EF + +NVL+++ GQT+TW+G+ + PLLP + + L L FY+KK +LL N +A RP+ Sbjct: 585 PEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWL 644 Query: 527 AS-SSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLF----TNYSAPWQVVPELVAL 581 AS ST F L+ L AAV L Y V + S CG F T Y A V L A Sbjct: 645 ASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAA 704 Query: 582 G-----LPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQV 636 G LP + + + + + F F + +L V+ + + + + I L++Q+ + Sbjct: 705 GPRVSWLPWVHR---YLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEG 761 Query: 637 QEKWHLVEDL 646 ++K L+ L Sbjct: 762 EDKIFLINKL 771 >gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sapiens] Length = 906 Score = 154 bits (388), Expect = 4e-37 Identities = 147/587 (25%), Positives = 256/587 (43%), Gaps = 53/587 (9%) Query: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPTLNLT 150 WE + +I FG+ + SYF FLR++ +NL+ L V++P V + P Sbjct: 234 WEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSIPRKTV 293 Query: 151 LQCPGSRQSPPGVL-RFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSV-YSIRLAYLLS 208 + + VL F + + + LFYG Y + Y + +AY + Sbjct: 294 PRAEEEKAMDFSVLWDFEGYIKY---------SALFYGYYNNQRTIGWLRYRLPMAYFMV 344 Query: 209 PLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEIS 268 ++ +R M T G+ S K+F+SWD+ I E A K I+ Sbjct: 345 GVSVFGYSLIIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLIGNSETADNKYASIT 404 Query: 269 NEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRV--NVLNGLLVVGAISAIFWATKYSQD 326 FK + + +Q++ + L +LRV N L + G+ I++ K SQ Sbjct: 405 TSFKESIVD-------EQESNKEENIHLTRFLRVLANFLIICCLCGSGYLIYFVVKRSQQ 457 Query: 327 -NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASL 385 +K +++ + V++L+ P LF + LENY P T + L L L +L Sbjct: 458 FSKMQNVSWYERNEVEIVMSLLGMFCPPLFETIAALENYHPRTGLKWQLGRIFALFLGNL 517 Query: 386 GMFSVSLGQTI-LCIGRDKSSCESYGYNVCDY-----------------------QCWEN 421 F ++L + L + +++ + + +Y CWE Sbjct: 518 YTFLLALMDDVHLKLANEETIKNITHWTLFNYYNSSGWNESVPRPPLHPADVPRGSCWET 577 Query: 422 SVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW-LER-----EEFLVPKNV 475 +VG E +L++ + L+T L R V RF W W LE EF + NV Sbjct: 578 AVGIEFMRLTVSDMLVTYITILLGDFLRACFV-RFMNYCWCWDLEAGFPSYAEFDISGNV 636 Query: 476 LDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQ 535 L ++ Q + WMG FY P L +N + L + Y + + ++ ++ R F+AS S F+ Sbjct: 637 LGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVPHERVFKASRSNNFYM 696 Query: 536 LVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLG 595 +LLL L L+ +P+ Y + S+ S+DCG F+ + + V+ E + P + +L Sbjct: 697 GLLLLVLFLSLLPVAYTIMSLPPSFDCGPFSGKNRMYDVLQETIENDFPTFLGKIFAFLA 756 Query: 596 SHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQL-VWQVQEKWH 641 + P ++++ L + S +++ +RA +LRK++ V + EK H Sbjct: 757 NPGLIIPAILLMFLAIYYLNSVSKSLSRANAQLRKKIQVLREVEKSH 803 >gi|21071070 transmembrane channel-like 1 [Homo sapiens] Length = 760 Score = 152 bits (383), Expect = 1e-36 Identities = 152/589 (25%), Positives = 256/589 (43%), Gaps = 59/589 (10%) Query: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP-LVWLRPPDPGPTLNL 149 WE + I FG+ + SYF FLR++ +N++ +LT S ++LP +W P P + Sbjct: 170 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 229 Query: 150 TLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSV-YSIRLAYLLS 208 + + + GVL N L + LFYG Y + + + L+Y L Sbjct: 230 P-RAEEASAANFGVLYDFNGLAQY--------SVLFYGYYDNKRTIGWMNFRLPLSYFLV 280 Query: 209 PLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEIS 268 + C+ F L+ M K + G S KVF+SWD+ I E A K + I+ Sbjct: 281 GIMCIGYSFLVVLKAMTKNIGDDGG-GDDNTFNFSWKVFTSWDYLIGNPETADNKFNSIT 339 Query: 269 NEFKVELEEGRRFQLMQQQTRAQTACRLLSYLR--VNVLNGLLVVGAISAIFWATKYSQD 326 FK + E + Q+ + L+ +LR N L + G+ IFWA K SQ+ Sbjct: 340 MNFKEAITEEKAAQVEEN-------VHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQE 392 Query: 327 NKEESLFLLLQYLPPGVIALVNFLG---PLLFTFLVQLENYPPNTEVNLTLIWCVVLKLA 383 ++ L + + +++ LG P LF +LE+Y P + L L L Sbjct: 393 FAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLG 452 Query: 384 SLGMFSVSLGQ----------------TILCIGRDKSSCESYGYN------------VCD 415 +L +F ++L T+ K+ S+ N V Sbjct: 453 NLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPR 512 Query: 416 YQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW-LER-----EEF 469 CWE VG+E +L++ + L T + R V RF W W LE EF Sbjct: 513 GPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFV-RFCNYCWCWDLEYGYPSYTEF 571 Query: 470 LVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS 529 + NVL ++ Q + WMG F+ P LP +N + L + Y + + ++ + +R F+AS Sbjct: 572 DISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASR 631 Query: 530 STFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQR 589 S F+ +LLL L L+ +P+ Y++ S+ S+DCG F+ + ++V+ E + P + Sbjct: 632 SNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAK 691 Query: 590 ALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQE 638 L L + +++++ L + + + A L+K++ Q E Sbjct: 692 ILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALE 740 >gi|122937502 transmembrane channel-like 3 [Homo sapiens] Length = 1100 Score = 108 bits (271), Expect = 1e-23 Identities = 66/222 (29%), Positives = 109/222 (49%), Gaps = 7/222 (3%) Query: 417 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW------LEREEFL 470 QCWE VG+E+ KLSI + L TVA L+ R L V R+ +W W E EF Sbjct: 498 QCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFV-RYLSDYWCWDLESKFPEYGEFK 556 Query: 471 VPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSS 530 + +NVL +V Q + WMG F+ P LP N + L Y++ + +L + + FRAS S Sbjct: 557 IAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRS 616 Query: 531 TFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRA 590 F+ +LL L L +P + + S +CG F+ + +V E + P Sbjct: 617 NNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSV 676 Query: 591 LHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQL 632 + ++ S P +++L +++ S ++ + H+L+ Q+ Sbjct: 677 VGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQI 718 Score = 90.5 bits (223), Expect = 5e-18 Identities = 84/306 (27%), Positives = 140/306 (45%), Gaps = 18/306 (5%) Query: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPTLNLT 150 WE + +I FG+G+ SYF FLR+L +N++ ++T +F+++P + P G T T Sbjct: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPF-GSTARKT 181 Query: 151 LQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAY-RVGPESSSVYSIRLAYLLSP 209 + P + S L + +W + G + LFYG Y R + Y + LAY L Sbjct: 182 I--PKEQVSSAQDL---DTVWSL--GGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFLVG 234 Query: 210 LACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISN 269 +A F L++M K +VF +WD+ I EAA K I N Sbjct: 235 MAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVN 294 Query: 270 EFKVELEEGRRFQLMQQQTRAQTAC-RLLSYLRVNVLNGLLVVGAISAIFWATKYSQ--D 326 + + E + + + + A T C R+++ N+L L + G+I I++ SQ + Sbjct: 295 SIREAILEEQ--EKKKSKNLAVTICLRIIA----NILVLLSLAGSIYLIYFVVDRSQKLE 348 Query: 327 NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASLG 386 ++ L L + V++LV + P F + LE Y P T + L +VL L +L Sbjct: 349 QSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNLY 408 Query: 387 MFSVSL 392 ++L Sbjct: 409 SLIIAL 414 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 40.0 bits (92), Expect = 0.008 Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP----CPGQ 708 PGP +PGP PA + P PG PG + P PGPS+ G R P PG Sbjct: 832 PGPPGAPGPAGPAGLPGHQEVLNLQGP-PGPPGPRGP-PGPSIPGPPGPRGPPGEGLPGP 889 Query: 709 HGAPAS 714 G P S Sbjct: 890 PGPPGS 895 Score = 31.2 bits (69), Expect = 3.5 Identities = 22/71 (30%), Positives = 25/71 (35%), Gaps = 12/71 (16%) Query: 653 PGPSDSPGPKYPASQASRP----------QSFCPGCPCPGSP-GHQAPRPGPSVVDAAGL 701 PGP G K P P + G P P GHQ PR + G+ Sbjct: 706 PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGI 765 Query: 702 RSPCPGQHGAP 712 R P PG G P Sbjct: 766 RGP-PGPSGDP 775 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 39.3 bits (90), Expect = 0.013 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 2/65 (3%) Query: 651 PEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710 P P P P P A+ A P++ P SPG +PGP AA L +P P Sbjct: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPG--PAQPGPRAQRAAPLAAPPPAPAA 186 Query: 711 APASA 715 PA A Sbjct: 187 PPAVA 191 Score = 30.0 bits (66), Expect = 7.9 Identities = 14/36 (38%), Positives = 16/36 (44%) Query: 658 SPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGP 693 SPGP P +A R P P +P AP GP Sbjct: 161 SPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP 196 >gi|56606142 complement component 1, q subcomponent-like 4 [Homo sapiens] Length = 238 Score = 38.9 bits (89), Expect = 0.017 Identities = 25/56 (44%), Positives = 28/56 (50%), Gaps = 5/56 (8%) Query: 654 GPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPG--PSVVDAAGLRSPCPG 707 GP PGP+ P + RP PG P PG PG AP G P + AGLR P G Sbjct: 70 GPPGPPGPRGPPGEPGRPGP--PGPPGPG-PGGVAPAAGYVPRIAFYAGLRRPHEG 122 >gi|134244285 Notch homolog 3 [Homo sapiens] Length = 2321 Score = 38.1 bits (87), Expect = 0.029 Identities = 29/74 (39%), Positives = 32/74 (43%), Gaps = 9/74 (12%) Query: 650 LPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSV-VDAAGLRSPCPGQ 708 LP P P PGP + A PQ PG P SP RP P + V G P G Sbjct: 2175 LPPPAP---PGPSFLLPLAPGPQLLNPGTPV--SPQE---RPPPYLAVPGHGEEYPAAGA 2226 Query: 709 HGAPASARRFRFPS 722 H +P AR R PS Sbjct: 2227 HSSPPKARFLRVPS 2240 Score = 33.1 bits (74), Expect = 0.93 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 11/80 (13%) Query: 637 QEKWHLVEDLSRLLPEP-GPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRP---- 691 QE+ H +D+ RLL +P GP PGP P +F PG S ++ RP Sbjct: 2013 QERLH--QDIVRLLDQPSGPRSPPGPHGLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGKA 2070 Query: 692 --GPSVVDAAG--LRSPCPG 707 GP G L CPG Sbjct: 2071 GLGPQGPRGRGKKLTLACPG 2090 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 37.7 bits (86), Expect = 0.038 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 8/63 (12%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712 PGP+ PGP P + P S PGSPG+Q P P +G P PG G Sbjct: 173 PGPAGPPGPPGPPGTSGHPGS-------PGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPS 224 Query: 713 ASA 715 A Sbjct: 225 GPA 227 Score = 37.7 bits (86), Expect = 0.038 Identities = 32/81 (39%), Positives = 34/81 (41%), Gaps = 23/81 (28%) Query: 653 PGPSDSPG---PKYPASQASRPQSFCPGCPCP----------GSPGHQAP--RPGP---- 693 PGPS SPG P PA P S PG P GSPG Q P PGP Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGS--PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIA 950 Query: 694 SVVDAAGLRSP--CPGQHGAP 712 + A GL P PG G+P Sbjct: 951 GITGARGLAGPPGMPGPRGSP 971 Score = 30.8 bits (68), Expect = 4.6 Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 17/76 (22%) Query: 652 EPGPSDSPGPK-------YPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGL--- 701 EPG +PG P + R ++ PG P G+PGH P PGP V AG Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP--GAPGHPGP-PGP--VGPAGKSGD 1063 Query: 702 --RSPCPGQHGAPASA 715 S G GAP A Sbjct: 1064 RGESGPAGPAGAPGPA 1079 Score = 30.4 bits (67), Expect = 6.1 Identities = 20/61 (32%), Positives = 22/61 (36%), Gaps = 8/61 (13%) Query: 654 GPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPA 713 GP+ PG K PA + G P P P A PG V PG G P Sbjct: 495 GPNGIPGEKGPAGER--------GAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG 546 Query: 714 S 714 S Sbjct: 547 S 547 Score = 30.4 bits (67), Expect = 6.1 Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 8/62 (12%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712 PGP SPGP+ ++ +P + G G + P PGP + + PG+ G P Sbjct: 965 PGPRGSPGPQGVKGESGKPGA-------NGLSGERGP-PGPQGLPGLAGTAGEPGRDGNP 1016 Query: 713 AS 714 S Sbjct: 1017 GS 1018 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 37.4 bits (85), Expect = 0.050 Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 9/72 (12%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPC-PGSPGHQAPRPGPSVVDAAGLRS-PCP---- 706 PGP GP + + PG P PGSPG Q PR P + G R P P Sbjct: 1432 PGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491 Query: 707 ---GQHGAPASA 715 G+ G P A Sbjct: 1492 GEKGERGPPGPA 1503 Score = 33.5 bits (75), Expect = 0.71 Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 2/64 (3%) Query: 652 EPGPSDSPGPKYP-ASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710 +PGPS PGP+ P R PG G G + R GP G+ PG G Sbjct: 1369 DPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGER-GPPGPGEGGIAPGEPGLPG 1427 Query: 711 APAS 714 P S Sbjct: 1428 LPGS 1431 Score = 30.4 bits (67), Expect = 6.1 Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 8/75 (10%) Query: 653 PGPSDSPGPK-YPASQASRPQSFCPGCP-CPGSPGHQAPRPGPSVVDAAGLR-SP-CPGQ 708 PG + +PGP+ P S ++ + PG PGSPG P A GL+ SP PG Sbjct: 1277 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAG---NPGTPGAPGLKGSPGLPGP 1333 Query: 709 HGAPASARRFRFPSG 723 G P R R P G Sbjct: 1334 RGDPGE-RGPRGPKG 1347 Score = 30.0 bits (66), Expect = 7.9 Identities = 25/72 (34%), Positives = 28/72 (38%), Gaps = 9/72 (12%) Query: 652 EPGPSDSPGPKYP---ASQASRPQSFCP----GCP-CPGSPGHQAPRPGPSVVDAAGLRS 703 +PGP PG + P +A P P G P PG PG PR V G Sbjct: 1584 DPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEG 1643 Query: 704 PCPGQHGAPASA 715 P PG G P A Sbjct: 1644 P-PGDPGLPGKA 1654 >gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sapiens] Length = 756 Score = 36.6 bits (83), Expect = 0.084 Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 651 PEPGPSDSPGPKYPASQASRPQSFCP-GCPCPGSPGHQAPRPGPSVVDAAGLRS-PCPGQ 708 PEPG D PG A + + P G P P SPG P PG + A + P PG Sbjct: 19 PEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPAPGL 78 Query: 709 HGAP 712 G P Sbjct: 79 EGGP 82 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 36.6 bits (83), Expect = 0.084 Identities = 28/71 (39%), Positives = 28/71 (39%), Gaps = 10/71 (14%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712 PGP S GP PA R P PG PG Q P PGP G R PG G P Sbjct: 1232 PGPPGSSGPPGPAGATGRAPK---DIPDPGPPGDQGP-PGPD-----GPRG-APGPPGLP 1281 Query: 713 ASARRFRFPSG 723 S R G Sbjct: 1282 GSVDLLRGEPG 1292 Score = 35.4 bits (80), Expect = 0.19 Identities = 24/69 (34%), Positives = 24/69 (34%), Gaps = 23/69 (33%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPC-------PGSPGHQAPRPGPSVVDAAGLRSP- 704 PGP PG PGCP G PG Q PR P G P Sbjct: 1084 PGPKGEPGS--------------PGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPP 1129 Query: 705 -CPGQHGAP 712 CPG HG P Sbjct: 1130 GCPGDHGMP 1138 Score = 31.2 bits (69), Expect = 3.5 Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 18/65 (27%) Query: 652 EPGPSDSPGPK-YPASQASRPQSFCPGC----PCPGSPGHQAPRPGPSVVDAAGLRSPCP 706 EPGP PGP P Q S+ PG PG PG + P PG P Sbjct: 495 EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGP-PG------------LP 541 Query: 707 GQHGA 711 G+HGA Sbjct: 542 GKHGA 546 Score = 30.0 bits (66), Expect = 7.9 Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 9/71 (12%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712 PGP PGP P P C G G + P P G P PG+ G P Sbjct: 1297 PGPPGPPGPPGPPGYKGFP-------GCDGKDGQKGPVGFPGPQGPHGFPGP-PGEKGLP 1348 Query: 713 ASARRFRFPSG 723 R + P+G Sbjct: 1349 GPPGR-KGPTG 1358 >gi|195972903 zinc finger protein 385A isoform a [Homo sapiens] Length = 386 Score = 36.6 bits (83), Expect = 0.084 Identities = 45/164 (27%), Positives = 64/164 (39%), Gaps = 32/164 (19%) Query: 563 GLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANA 622 GLF+NYS + P+ + L SH F PLL V++ + Q + N+ Sbjct: 42 GLFSNYST------------MDPVQKAVL----SHTFGGPLLKTKRPVISCNICQIRFNS 85 Query: 623 RA---IHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQ-------ASRPQ 672 ++ H + +V+ +E EPG + P P S A RP Sbjct: 86 QSQAEAHYKGNRHARRVKG----IEAAKTRGREPGVREPGDPAPPGSTPTNGDGVAPRPV 141 Query: 673 SFCPGC-PCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASA 715 S G P PGSP Q P P + G + G+ G PA A Sbjct: 142 SMENGLGPAPGSPEKQPGSPSPPSIPETG-QGVTKGEGGTPAPA 184 >gi|24308079 zinc finger protein 385A isoform c [Homo sapiens] Length = 366 Score = 36.6 bits (83), Expect = 0.084 Identities = 45/164 (27%), Positives = 64/164 (39%), Gaps = 32/164 (19%) Query: 563 GLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANA 622 GLF+NYS + P+ + L SH F PLL V++ + Q + N+ Sbjct: 22 GLFSNYST------------MDPVQKAVL----SHTFGGPLLKTKRPVISCNICQIRFNS 65 Query: 623 RA---IHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQ-------ASRPQ 672 ++ H + +V+ +E EPG + P P S A RP Sbjct: 66 QSQAEAHYKGNRHARRVKG----IEAAKTRGREPGVREPGDPAPPGSTPTNGDGVAPRPV 121 Query: 673 SFCPGC-PCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASA 715 S G P PGSP Q P P + G + G+ G PA A Sbjct: 122 SMENGLGPAPGSPEKQPGSPSPPSIPETG-QGVTKGEGGTPAPA 164 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 36.2 bits (82), Expect = 0.11 Identities = 27/65 (41%), Positives = 29/65 (44%), Gaps = 9/65 (13%) Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPG-HQAPRP-GPSVVDAAGLRSP--CPG 707 EPGP PGP+ P P F PG P G PG H P P GP G P PG Sbjct: 78 EPGPPGKPGPRGPPG----PPGF-PGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPG 132 Query: 708 QHGAP 712 + G P Sbjct: 133 KVGPP 137 Score = 35.8 bits (81), Expect = 0.14 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 19/83 (22%) Query: 653 PGPSDSPGPK---------YPASQASRPQSFCPGCPCP-GSPGHQAPRPGPSVVDAAGLR 702 PGP PGP P + + +S PG P P G PG P+ GP VD G+ Sbjct: 225 PGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPK-GPPGVDGVGV- 282 Query: 703 SPCPGQHGAPASARRFRFPSGAE 725 PG G P + PSGA+ Sbjct: 283 ---PGAAGLPGP----QGPSGAK 298 Score = 33.1 bits (74), Expect = 0.93 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCPCP-GSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710 +PG PGP P + ++ PG P G PG R P + GLR P PG G Sbjct: 104 KPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGP-PGPPG 162 Query: 711 AP 712 P Sbjct: 163 LP 164 Score = 31.6 bits (70), Expect = 2.7 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 3/62 (4%) Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-CPGQHG 710 EPGP PGP P + + + PG+PG P + AGL P G G Sbjct: 189 EPGPQGEPGP--PGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPG 246 Query: 711 AP 712 AP Sbjct: 247 AP 248 Score = 30.8 bits (68), Expect = 4.6 Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 13/70 (18%) Query: 654 GPSDSPGPKYPASQASRPQSFC-----PGCPCP------GSPGHQAPRPGPSVVDAAGLR 702 GPS PG + PA PQ PG P P G PG P P V + G+ Sbjct: 460 GPSGIPGLQGPAGPIG-PQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGIT 518 Query: 703 SPCPGQHGAP 712 P PG G P Sbjct: 519 GP-PGPPGPP 527 >gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] Length = 1796 Score = 36.2 bits (82), Expect = 0.11 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 12/67 (17%) Query: 654 GPSDSPGPKYPASQASRPQSFCPGCPCP-------GSPGHQAP--RPG---PSVVDAAGL 701 GP PGP P+ ++ PG P P G PG Q P +PG PS A G+ Sbjct: 1710 GPRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQPGYCDPSSCSAYGV 1769 Query: 702 RSPCPGQ 708 R+P P Q Sbjct: 1770 RAPHPDQ 1776 Score = 31.2 bits (69), Expect = 3.5 Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPC-PGSPGHQAPRPGPSVVDAAGLRSPCPGQHGA 711 PGP PGP+ P+ + + PG G G P+ P V + G R PGQ G Sbjct: 1497 PGPQGPPGPQGPSGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPG-RDGSPGQRGL 1555 Query: 712 P 712 P Sbjct: 1556 P 1556 >gi|7662302 TBK1 binding protein 1 [Homo sapiens] Length = 615 Score = 35.8 bits (81), Expect = 0.14 Identities = 21/71 (29%), Positives = 26/71 (36%) Query: 651 PEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710 P P P P P Q+ PQ P PCP ++P RSP P Sbjct: 348 PSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQ 407 Query: 711 APASARRFRFP 721 +P+ RR P Sbjct: 408 SPSPQRRSPVP 418 >gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] Length = 727 Score = 35.4 bits (80), Expect = 0.19 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 12/82 (14%) Query: 643 VEDLSRLLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLR 702 + S P P+DSP P+ + + S P S G AP P P VV A +R Sbjct: 345 IASASTTAPASSPADSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIR 404 Query: 703 ------------SPCPGQHGAP 712 SP PG + +P Sbjct: 405 PSVYQPVPASTYSPSPGANYSP 426 Score = 30.8 bits (68), Expect = 4.6 Identities = 27/82 (32%), Positives = 31/82 (37%), Gaps = 16/82 (19%) Query: 651 PEPGPSDSPGPKY-----PASQASRP---------QSFCPGCPCPGSPGHQAPRPGPSVV 696 P P P+ +P P PA ASRP Q F PG PR GP+ Sbjct: 463 PSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYT 522 Query: 697 DAAGLRSPCPGQHGAPASARRF 718 AG + P P G A RF Sbjct: 523 -PAGPQVP-PLARGTVQRAERF 542 >gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens] Length = 717 Score = 35.4 bits (80), Expect = 0.19 Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 9/64 (14%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-----CPG 707 PGP PGP P P P PG PG P+ P + G + PG Sbjct: 272 PGPPGPPGPSGPLGHPGLPGPMGP----PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPG 327 Query: 708 QHGA 711 +HGA Sbjct: 328 KHGA 331 Score = 30.4 bits (67), Expect = 6.1 Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 5/46 (10%) Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCP----CPGSPGHQAPRPGP 693 E G + SPG K A + P + PG P PG PG Q PGP Sbjct: 543 ETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGV-PGP 587 Score = 30.0 bits (66), Expect = 7.9 Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 5/41 (12%) Query: 676 PGCPCPGSPGHQAPRPG-PSVVDAAGLRSPCPGQHGAPASA 715 PGC CP P RPG P A G+ PG+ G+P A Sbjct: 115 PGCNCPPGPPGPTGRPGLPGDKGAIGM----PGRVGSPGDA 151 >gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens] Length = 610 Score = 35.4 bits (80), Expect = 0.19 Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 9/64 (14%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-----CPG 707 PGP PGP P P P PG PG P+ P + G + PG Sbjct: 221 PGPPGPPGPSGPLGHPGLPGPMGP----PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPG 276 Query: 708 QHGA 711 +HGA Sbjct: 277 KHGA 280 >gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens] Length = 655 Score = 35.4 bits (80), Expect = 0.19 Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 9/64 (14%) Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-----CPG 707 PGP PGP P P P PG PG P+ P + G + PG Sbjct: 210 PGPPGPPGPSGPLGHPGLPGPMGP----PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPG 265 Query: 708 QHGA 711 +HGA Sbjct: 266 KHGA 269 Score = 30.4 bits (67), Expect = 6.1 Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 5/46 (10%) Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCP----CPGSPGHQAPRPGP 693 E G + SPG K A + P + PG P PG PG Q PGP Sbjct: 481 ETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGV-PGP 525 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.140 0.445 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,354,615 Number of Sequences: 37866 Number of extensions: 1680400 Number of successful extensions: 10574 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 238 Number of HSP's that attempted gapping in prelim test: 9353 Number of HSP's gapped (non-prelim): 1375 length of query: 726 length of database: 18,247,518 effective HSP length: 110 effective length of query: 616 effective length of database: 14,082,258 effective search space: 8674670928 effective search space used: 8674670928 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.