Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 23110952
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]
(363 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens] 748 0.0
gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens] 532 e-151
gi|119372298 pepsinogen 3, group I [Homo sapiens] 268 7e-72
gi|23943854 pepsinogen 5, group I [Homo sapiens] 268 7e-72
gi|119372302 pepsinogen 4, group I [Homo sapiens] 267 1e-71
gi|4505757 progastricsin (pepsinogen C) [Homo sapiens] 248 5e-66
gi|4503143 cathepsin D preproprotein [Homo sapiens] 215 4e-56
gi|4758754 napsin A preproprotein [Homo sapiens] 210 1e-54
gi|4506475 renin preproprotein [Homo sapiens] 176 4e-44
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote... 89 6e-18
gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprot... 79 5e-15
gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprot... 79 5e-15
gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprot... 79 5e-15
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot... 78 1e-14
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot... 59 5e-09
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot... 52 1e-06
gi|138175817 zinc finger protein 236 [Homo sapiens] 33 0.40
gi|102467481 sphingomyelin phosphodiesterase 4 isoform 2 [Homo s... 30 2.6
gi|102467484 sphingomyelin phosphodiesterase 4 isoform 1 [Homo s... 30 2.6
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 30 4.4
gi|82775371 coiled-coil domain containing 93 [Homo sapiens] 30 4.4
gi|42490753 TEA domain family member 3 [Homo sapiens] 30 4.4
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 29 5.8
gi|239743797 PREDICTED: similar to cell recognition molecule CAS... 29 5.8
gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 29 5.8
gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 29 5.8
gi|26667219 eyes absent 1 isoform c [Homo sapiens] 29 7.5
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 29 7.5
gi|59710085 hypothetical protein LOC146562 [Homo sapiens] 29 7.5
gi|13129124 caspase recruitment domain protein 14 isoform 1 [Hom... 28 9.8
>gi|23110952 cathepsin E isoform b preproprotein [Homo sapiens]
Length = 363
Score = 748 bits (1930), Expect = 0.0
Identities = 363/363 (100%), Positives = 363/363 (100%)
Query: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC 60
MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC
Sbjct: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC 60
Query: 61 SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF 120
SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF
Sbjct: 61 SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF 120
Query: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180
QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE
Sbjct: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180
Query: 181 FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 240
FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH
Sbjct: 181 FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 240
Query: 241 FSGSLNWVPVTKQAYWQIALDNMLWSVPTLTSCRMSPSPLTESPIPSAQLPTPYWTSWME 300
FSGSLNWVPVTKQAYWQIALDNMLWSVPTLTSCRMSPSPLTESPIPSAQLPTPYWTSWME
Sbjct: 241 FSGSLNWVPVTKQAYWQIALDNMLWSVPTLTSCRMSPSPLTESPIPSAQLPTPYWTSWME 300
Query: 301 CSSAAVAFKDLTSTLQLGPSGSWGMSSFDSFTQSLTVGITVWDWPQQSPKEGPCVCACLS 360
CSSAAVAFKDLTSTLQLGPSGSWGMSSFDSFTQSLTVGITVWDWPQQSPKEGPCVCACLS
Sbjct: 301 CSSAAVAFKDLTSTLQLGPSGSWGMSSFDSFTQSLTVGITVWDWPQQSPKEGPCVCACLS 360
Query: 361 DRP 363
DRP
Sbjct: 361 DRP 363
>gi|4503145 cathepsin E isoform a preproprotein [Homo sapiens]
Length = 396
Score = 532 bits (1371), Expect = e-151
Identities = 262/263 (99%), Positives = 263/263 (100%)
Query: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC 60
MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC
Sbjct: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC 60
Query: 61 SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF 120
SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF
Sbjct: 61 SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF 120
Query: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180
QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE
Sbjct: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180
Query: 181 FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 240
FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH
Sbjct: 181 FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 240
Query: 241 FSGSLNWVPVTKQAYWQIALDNM 263
FSGSLNWVPVTKQAYWQIALDN+
Sbjct: 241 FSGSLNWVPVTKQAYWQIALDNI 263
>gi|119372298 pepsinogen 3, group I [Homo sapiens]
Length = 388
Score = 268 bits (684), Expect = 7e-72
Identities = 140/265 (52%), Positives = 183/265 (69%), Gaps = 8/265 (3%)
Query: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQ--FTE 58
MK LLLL LV L ++ +++VPL R SL++ L R L +F K HNL+ + F +
Sbjct: 1 MKWLLLLGLVAL----SECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQ 56
Query: 59 SCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHS 118
+ ++PL NYLDMEYFGTI IG+P Q+FTV+FDTGSSNLWVPSVYC+S AC H+
Sbjct: 57 WKAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHN 116
Query: 119 RFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVD 178
RF P SSTY ++ SI YGTGS++GI+G D V V G++ Q FG S TEPG
Sbjct: 117 RFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYY 176
Query: 179 AEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDH 238
A FDGILGL YPS++ G TPVFDN+ Q LV +FSVY+S++ + +GS +IFGG D
Sbjct: 177 APFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQ--SGSVVIFGGIDS 234
Query: 239 SHFSGSLNWVPVTKQAYWQIALDNM 263
S+++GSLNWVPVT + YWQI +D++
Sbjct: 235 SYYTGSLNWVPVTVEGYWQITVDSI 259
>gi|23943854 pepsinogen 5, group I [Homo sapiens]
Length = 388
Score = 268 bits (684), Expect = 7e-72
Identities = 141/272 (51%), Positives = 186/272 (68%), Gaps = 8/272 (2%)
Query: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQ--FTE 58
MK LLLL LV L ++ +++VPL R SL++ L R L +F K HNL+ + F +
Sbjct: 1 MKWLLLLGLVAL----SECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQ 56
Query: 59 SCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHS 118
+ ++PL NYLDMEYFGTI IG+P Q+FTV+FDTGSSNLWVPSVYC+S AC H+
Sbjct: 57 WEAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHN 116
Query: 119 RFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVD 178
RF P SSTY ++ SI YGTGS++GI+G D V V G++ Q FG S TEPG
Sbjct: 117 RFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYY 176
Query: 179 AEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDH 238
A FDGILGL YPS++ G TPVFDN+ Q LV +FSVY+S++ + +GS +IFGG D
Sbjct: 177 APFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDK--SGSVVIFGGIDS 234
Query: 239 SHFSGSLNWVPVTKQAYWQIALDNMLWSVPTL 270
S+++GSLNWVPVT + YWQI +D++ + T+
Sbjct: 235 SYYTGSLNWVPVTVEGYWQITVDSITMNGETI 266
>gi|119372302 pepsinogen 4, group I [Homo sapiens]
Length = 388
Score = 267 bits (683), Expect = 1e-71
Identities = 140/265 (52%), Positives = 183/265 (69%), Gaps = 8/265 (3%)
Query: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQ--FTE 58
MK LLLL LV L ++ +++VPL R SL++ L R L +F K HNL+ + F +
Sbjct: 1 MKWLLLLGLVAL----SECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQ 56
Query: 59 SCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHS 118
+ ++PL NYLDMEYFGTI IG+P Q+FTV+FDTGSSNLWVPSVYC+S AC H+
Sbjct: 57 WEAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHN 116
Query: 119 RFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVD 178
RF P SSTY ++ SI YGTGS++GI+G D V V G++ Q FG S TEPG
Sbjct: 117 RFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYY 176
Query: 179 AEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDH 238
A FDGILGL YPS++ G TPVFDN+ Q LV +FSVY+S++ + +GS +IFGG D
Sbjct: 177 APFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQ--SGSVVIFGGIDS 234
Query: 239 SHFSGSLNWVPVTKQAYWQIALDNM 263
S+++GSLNWVPVT + YWQI +D++
Sbjct: 235 SYYTGSLNWVPVTVEGYWQITVDSI 259
>gi|4505757 progastricsin (pepsinogen C) [Homo sapiens]
Length = 388
Score = 248 bits (634), Expect = 5e-66
Identities = 126/300 (42%), Positives = 190/300 (63%), Gaps = 5/300 (1%)
Query: 5 LLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQ 64
++++LV L+L EA ++ +VPL++ S+++ ++ + L EF ++H D +
Sbjct: 4 MVVVLVCLQLLEA--AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSV 61
Query: 65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQ 124
+ EP+ Y+D YFG ISIG+PPQNF V+FDTGSSNLWVPSVYC S AC +HSRF PS+
Sbjct: 62 TY-EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSE 119
Query: 125 SSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGI 184
SSTYS GQ+FS+QYG+GSL+G G D ++V+ + V Q+FG S EPG FV A+FDGI
Sbjct: 120 SSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGI 179
Query: 185 LGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGS 244
+GL YP+L+V T M+ + + P+FSVY+ SN +G +G ++FGG D S ++G
Sbjct: 180 MGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYL-SNQQGSSGGAVVFGGVDSSLYTGQ 238
Query: 245 LNWVPVTKQAYWQIALDNMLWSVPTLTSCRMSPSPLTESPIPSAQLPTPYWTSWMECSSA 304
+ W PVT++ YWQI ++ L C + ++ +P Y ++ ++ + A
Sbjct: 239 IYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGA 298
>gi|4503143 cathepsin D preproprotein [Homo sapiens]
Length = 412
Score = 215 bits (548), Expect = 4e-56
Identities = 115/277 (41%), Positives = 163/277 (58%), Gaps = 14/277 (5%)
Query: 1 MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKL-RARSQLSEFWKSHNLDMIQFTES 59
M+ LL L L L +L R+PL + S+++ + + + +
Sbjct: 1 MQPSSLLPLALCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVP 60
Query: 60 CSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTH 117
+ E L NY+D +Y+G I IG+PPQ FTV+FDTGSSNLWVPS++C AC H
Sbjct: 61 AVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIH 120
Query: 118 SRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVE-----------GLTVVGQQFG 166
++ +SSTY + G SF I YG+GSLSG + D VSV G+ V Q FG
Sbjct: 121 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFG 180
Query: 167 ESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGG 226
E+ +PG TF+ A+FDGILG+ YP ++V V PVFDN+M Q LVD +FS Y+S +P+
Sbjct: 181 EATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQ 240
Query: 227 AGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNM 263
G EL+ GG D ++ GSL+++ VT++AYWQ+ LD +
Sbjct: 241 PGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQV 277
>gi|4758754 napsin A preproprotein [Homo sapiens]
Length = 420
Score = 210 bits (535), Expect = 1e-54
Identities = 118/271 (43%), Positives = 161/271 (59%), Gaps = 8/271 (2%)
Query: 5 LLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQ 64
LLLLL LL + + +L R+PL R ++ L L W+ ++ + D+
Sbjct: 10 LLLLLPLLNVEPSGATLIRIPLHRVQPGRRILN----LLRGWREP-AELPKLGAPSPGDK 64
Query: 65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQP 122
PL NY D++YFG I +G+PPQNFTV FDTGSSNLWVPS C S C H RF P
Sbjct: 65 PIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDP 124
Query: 123 SQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFD 182
SS++ G F+IQYGTG + GI+ D++++ G+ FGE++ EP F A FD
Sbjct: 125 KASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFD 184
Query: 183 GILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFS 242
GILGLG+P L+V GV P D ++ Q L+D P+FS Y++ +PE G EL+ GG D +H+
Sbjct: 185 GILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYI 244
Query: 243 GSLNWVPVTKQAYWQIALDNMLWSVPTLTSC 273
L +VPVT AYWQI ++ + P LT C
Sbjct: 245 PPLTFVPVTVPAYWQIHMERVKVG-PGLTLC 274
>gi|4506475 renin preproprotein [Homo sapiens]
Length = 406
Score = 176 bits (445), Expect = 4e-44
Identities = 92/253 (36%), Positives = 148/253 (58%), Gaps = 9/253 (3%)
Query: 23 RVPLRRHPSLKKKLRARS-QLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYFGT 81
R+ L+R PS+++ L+ R ++ + M + T + ++ L NY+D +Y+G
Sbjct: 33 RIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLG---NTTSSVILTNYMDTQYYGE 89
Query: 82 ISIGSPPQNFTVIFDTGSSNLWVPSVYCTS--PACKTHSRFQPSQSSTYSQPGQSFSIQY 139
I IG+PPQ F V+FDTGSSN+WVPS C+ AC H F S SS+Y G +++Y
Sbjct: 90 IGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRY 149
Query: 140 GTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTP 199
TG++SG + D ++V G+TV Q FGE P F+ AEFDG++G+G+ A+G VTP
Sbjct: 150 STGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTP 208
Query: 200 VFDNMMAQNLVDLPMFSVYMSSNPEG--GAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQ 257
+FDN+++Q ++ +FS Y + + E G +++ GG D H+ G+ +++ + K WQ
Sbjct: 209 IFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQ 268
Query: 258 IALDNMLWSVPTL 270
I + + TL
Sbjct: 269 IQMKGVSVGSSTL 281
>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
[Homo sapiens]
Length = 501
Score = 89.0 bits (219), Expect = 6e-18
Identities = 59/194 (30%), Positives = 98/194 (50%), Gaps = 15/194 (7%)
Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVD-AEFDGILGLGYPSLAV- 194
Y G G +G D VS+ G V + ++TE + F++ + ++GILGL Y +A
Sbjct: 131 PYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP 190
Query: 195 -GGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPE---GGAGSELIFGGYDHSHFSGSLN 246
+ P FD+++ Q NL L + N G +I GG DHS ++GSL
Sbjct: 191 DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLW 250
Query: 247 WVPVTKQAYWQIAL 260
+ P+ ++ Y+++ +
Sbjct: 251 YTPIRREWYYEVII 264
>gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprotein
[Homo sapiens]
Length = 518
Score = 79.3 bits (194), Expect = 5e-15
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 12/191 (6%)
Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Y+ + IG+PPQ ++ DTGSSN V +P + F +SSTY G ++
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 147
Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLA-- 193
+Y GS +G +G D V++ +G ++ E F+ +++GILGL Y +LA
Sbjct: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 207
Query: 194 VGGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249
+ FD+++ Q N+ + M + G G L+ GG + S + G + + P
Sbjct: 208 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 267
Query: 250 VTKQAYWQIAL 260
+ ++ Y+QI +
Sbjct: 268 IKEEWYYQIEI 278
>gi|21040362 beta-site APP-cleaving enzyme 2 isoform B preproprotein
[Homo sapiens]
Length = 396
Score = 79.3 bits (194), Expect = 5e-15
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 12/191 (6%)
Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Y+ + IG+PPQ ++ DTGSSN V +P + F +SSTY G ++
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 147
Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLA-- 193
+Y GS +G +G D V++ +G ++ E F+ +++GILGL Y +LA
Sbjct: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 207
Query: 194 VGGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249
+ FD+++ Q N+ + M + G G L+ GG + S + G + + P
Sbjct: 208 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 267
Query: 250 VTKQAYWQIAL 260
+ ++ Y+QI +
Sbjct: 268 IKEEWYYQIEI 278
>gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprotein
[Homo sapiens]
Length = 468
Score = 79.3 bits (194), Expect = 5e-15
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 12/191 (6%)
Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Y+ + IG+PPQ ++ DTGSSN V +P + F +SSTY G ++
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 147
Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLA-- 193
+Y GS +G +G D V++ +G ++ E F+ +++GILGL Y +LA
Sbjct: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 207
Query: 194 VGGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249
+ FD+++ Q N+ + M + G G L+ GG + S + G + + P
Sbjct: 208 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 267
Query: 250 VTKQAYWQIAL 260
+ ++ Y+QI +
Sbjct: 268 IKEEWYYQIEI 278
>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
[Homo sapiens]
Length = 476
Score = 78.2 bits (191), Expect = 1e-14
Identities = 53/187 (28%), Positives = 92/187 (49%), Gaps = 26/187 (13%)
Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVD-AEFDGILGLGYPSLA-- 193
Y G G +G D VS+ G V + ++TE + F++ + ++GILGL Y +A
Sbjct: 131 PYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARL 190
Query: 194 VGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQ 253
G P+ + + ++ G +I GG DHS ++GSL + P+ ++
Sbjct: 191 CGAGFPLNQSEVLASV------------------GGSMIIGGIDHSLYTGSLWYTPIRRE 232
Query: 254 AYWQIAL 260
Y+++ +
Sbjct: 233 WYYEVII 239
>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
[Homo sapiens]
Length = 457
Score = 59.3 bits (142), Expect = 5e-09
Identities = 46/190 (24%), Positives = 74/190 (38%), Gaps = 51/190 (26%)
Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGV 197
Y G G +G D L +
Sbjct: 131 PYTQGKWEGELGTD----------------------------------------LPDDSL 150
Query: 198 TPVFDNMMAQ----NLVDLPMFSVYMSSNPE---GGAGSELIFGGYDHSHFSGSLNWVPV 250
P FD+++ Q NL L + N G +I GG DHS ++GSL + P+
Sbjct: 151 EPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPI 210
Query: 251 TKQAYWQIAL 260
++ Y+++ +
Sbjct: 211 RREWYYEVII 220
>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
[Homo sapiens]
Length = 432
Score = 51.6 bits (122), Expect = 1e-06
Identities = 41/183 (22%), Positives = 66/183 (36%), Gaps = 62/183 (33%)
Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGV 197
Y G G +G D + G G+P
Sbjct: 131 PYTQGKWEGELGTDL-------------------------------LCGAGFP------- 152
Query: 198 TPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQ 257
S G +I GG DHS ++GSL + P+ ++ Y++
Sbjct: 153 --------------------LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYE 192
Query: 258 IAL 260
+ +
Sbjct: 193 VII 195
>gi|138175817 zinc finger protein 236 [Homo sapiens]
Length = 1845
Score = 33.1 bits (74), Expect = 0.40
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 81 TISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYG 140
T S GSP + I + +++ +PS SP+ + S S + ++
Sbjct: 1515 TSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADT 1574
Query: 141 TGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTP 199
G LSG G D V++ +T GQQF +T+P G G G P + + TP
Sbjct: 1575 QGMLSG--GLDTVTL-NITSQGQQFPALLTDP-------SLSGQGGAGSPQVILVSHTP 1623
>gi|102467481 sphingomyelin phosphodiesterase 4 isoform 2 [Homo
sapiens]
Length = 866
Score = 30.4 bits (67), Expect = 2.6
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 14/106 (13%)
Query: 199 PVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWV-----PV--- 250
PV ++ L D P++ + P GG G L +++ F +L+ + PV
Sbjct: 156 PVKASIQECILPDSPLYHNKVQFTPTGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLH 215
Query: 251 --TKQAYWQIALDNML-WSVPTLTSCRMSPSPLTESPIPSAQLPTP 293
T + I +D L W +PT S P PL+ SP ++ P P
Sbjct: 216 VRTSDCAYFILVDRYLSWFLPTEGSV---PPPLSSSPGGTSPSPPP 258
>gi|102467484 sphingomyelin phosphodiesterase 4 isoform 1 [Homo
sapiens]
Length = 837
Score = 30.4 bits (67), Expect = 2.6
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 14/106 (13%)
Query: 199 PVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWV-----PV--- 250
PV ++ L D P++ + P GG G L +++ F +L+ + PV
Sbjct: 156 PVKASIQECILPDSPLYHNKVQFTPTGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLH 215
Query: 251 --TKQAYWQIALDNML-WSVPTLTSCRMSPSPLTESPIPSAQLPTP 293
T + I +D L W +PT S P PL+ SP ++ P P
Sbjct: 216 VRTSDCAYFILVDRYLSWFLPTEGSV---PPPLSSSPGGTSPSPPP 258
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 29.6 bits (65), Expect = 4.4
Identities = 16/55 (29%), Positives = 28/55 (50%)
Query: 76 MEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQ 130
++ F +I+ G P FT+ F+TG N+ P + PA K R S + +++
Sbjct: 2212 LKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAE 2266
>gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
Length = 631
Score = 29.6 bits (65), Expect = 4.4
Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 8/96 (8%)
Query: 2 KTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCS 61
KTL L +L + Q +L ++ + PS+ + LRA ++E KS +F C
Sbjct: 352 KTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQ---EFKAHCR 408
Query: 62 MDQSAKEPLINYLDMEYF-----GTISIGSPPQNFT 92
+ + + I L E T+S G PP T
Sbjct: 409 EEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLT 444
>gi|42490753 TEA domain family member 3 [Homo sapiens]
Length = 435
Score = 29.6 bits (65), Expect = 4.4
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 310 DLTSTLQLGPSGSWGMSSFDSFTQSLTVGIT 340
DL ST+Q GP +G+SS S S+T+ ++
Sbjct: 302 DLNSTIQEGPGAFYGVSSQYSSADSMTISVS 332
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 29.3 bits (64), Expect = 5.8
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 84 IGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHS 118
I PP T+ +++ SS+L P+ +SPACK S
Sbjct: 385 INPPPVAGTISYNSTSSSLEQPNAGSSSPACKASS 419
>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
[Homo sapiens]
Length = 944
Score = 29.3 bits (64), Expect = 5.8
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 11/57 (19%)
Query: 273 CRMSPSP-LTESPIPSAQLPT-----PYWTSWMECSSAAVAFKDLTSTLQLGPSGSW 323
CR P+P + ++P P+A +P P + + C SA TS QLGP +W
Sbjct: 122 CRPPPAPSVRDAPEPAASVPGAAPRGPERSRKLRCESAGP-----TSETQLGPGAAW 173
>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
[Homo sapiens]
Length = 2269
Score = 29.3 bits (64), Expect = 5.8
Identities = 32/146 (21%), Positives = 55/146 (37%), Gaps = 15/146 (10%)
Query: 27 RRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEP--LINYLDMEYFGTISI 84
RR KK +RA + + WK +++ C + ++P L+ Y D I
Sbjct: 1299 RRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYR-----DI 1353
Query: 85 GSPPQNFTVIFDT-GSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGS 143
P +F + +T + N P +C R S + Y+ P + I T
Sbjct: 1354 IDTPMDFGTVRETLDAGNYDSPLEFCKD------IRLIFSNAKAYT-PNKRSKIYSMTLR 1406
Query: 144 LSGIIGADQVSVEGLTVVGQQFGESV 169
LS + + +GQ+F E +
Sbjct: 1407 LSALFEEKMKKISSDFKIGQKFNEKL 1432
>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
[Homo sapiens]
Length = 2320
Score = 29.3 bits (64), Expect = 5.8
Identities = 32/146 (21%), Positives = 55/146 (37%), Gaps = 15/146 (10%)
Query: 27 RRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEP--LINYLDMEYFGTISI 84
RR KK +RA + + WK +++ C + ++P L+ Y D I
Sbjct: 1299 RRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYR-----DI 1353
Query: 85 GSPPQNFTVIFDT-GSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGS 143
P +F + +T + N P +C R S + Y+ P + I T
Sbjct: 1354 IDTPMDFGTVRETLDAGNYDSPLEFCKD------IRLIFSNAKAYT-PNKRSKIYSMTLR 1406
Query: 144 LSGIIGADQVSVEGLTVVGQQFGESV 169
LS + + +GQ+F E +
Sbjct: 1407 LSALFEEKMKKISSDFKIGQKFNEKL 1432
>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
Length = 557
Score = 28.9 bits (63), Expect = 7.5
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 3/64 (4%)
Query: 121 QPSQSSTYSQPGQSFSI-QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDA 179
Q + +TY QPGQ + I YG + G+ + G G F S +PGQ
Sbjct: 120 QATAYATYPQPGQPYGISSYGIKTEGGLSQSQSPGQTGFLSYGTSF--STPQPGQAPYSY 177
Query: 180 EFDG 183
+ G
Sbjct: 178 QMQG 181
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 28.9 bits (63), Expect = 7.5
Identities = 14/50 (28%), Positives = 23/50 (46%)
Query: 275 MSPSPLTESPIPSAQLPTPYWTSWMECSSAAVAFKDLTSTLQLGPSGSWG 324
+SP+P +P P + P P+ E S A ++ + L+ GP G
Sbjct: 1857 LSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLG 1906
>gi|59710085 hypothetical protein LOC146562 [Homo sapiens]
Length = 520
Score = 28.9 bits (63), Expect = 7.5
Identities = 13/46 (28%), Positives = 24/46 (52%), Gaps = 3/46 (6%)
Query: 104 VPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIG 149
VP+ T P C+ ++R + + S PG+ F +G +S ++G
Sbjct: 96 VPAELATEPGCRQNTRTKDASSQEGRDPGRPFE---SSGEVSALLG 138
>gi|13129124 caspase recruitment domain protein 14 isoform 1 [Homo
sapiens]
Length = 1004
Score = 28.5 bits (62), Expect = 9.8
Identities = 13/46 (28%), Positives = 24/46 (52%)
Query: 14 LGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTES 59
L EA+GS + R H ++ + A Q ++W+ ++QF +S
Sbjct: 291 LDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKS 336
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,402,756
Number of Sequences: 37866
Number of extensions: 747892
Number of successful extensions: 2119
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2053
Number of HSP's gapped (non-prelim): 39
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.