Guide to the Human Genome
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Search of human proteins with 22547204

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22547204 hairless protein isoform a [Homo sapiens]
         (1189 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22547204 hairless protein isoform a [Homo sapiens]                2528   0.0  
gi|22547207 hairless protein isoform b [Homo sapiens]                2373   0.0  
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]     254   3e-67
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]    238   3e-62
gi|226442779 jumonji domain containing 1A [Homo sapiens]              228   2e-59
gi|20357522 jumonji domain containing 1A [Homo sapiens]               228   2e-59
gi|38372909 jumonji domain containing 1B [Homo sapiens]               175   3e-43
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      45   5e-04
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    43   0.002
gi|156938257 leucine rich repeat containing 16B [Homo sapiens]         43   0.002
gi|116734704 interferon regulatory factor 2 binding protein 2 is...    43   0.002
gi|148612825 Rap GTPase interactor [Homo sapiens]                      42   0.003
gi|116734706 interferon regulatory factor 2 binding protein 2 is...    42   0.003
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          42   0.005
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...    42   0.005
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]       42   0.005
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    42   0.005
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...    42   0.005
gi|31442420 shroom family member 1 [Homo sapiens]                      42   0.005
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  41   0.008
gi|118402590 myosin XV [Homo sapiens]                                  41   0.008
gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho...    41   0.008
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    40   0.010
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    40   0.010
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       40   0.010
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         40   0.017
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    39   0.023
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    39   0.023
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    39   0.023
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    39   0.023

>gi|22547204 hairless protein isoform a [Homo sapiens]
          Length = 1189

 Score = 2528 bits (6551), Expect = 0.0
 Identities = 1189/1189 (100%), Positives = 1189/1189 (100%)

Query: 1    MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW 60
            MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW
Sbjct: 1    MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW 60

Query: 61   LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG 120
            LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG
Sbjct: 61   LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG 120

Query: 121  PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP 180
            PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP
Sbjct: 121  PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP 180

Query: 181  LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA 240
            LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA
Sbjct: 181  LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA 240

Query: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 300
            GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG
Sbjct: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 300

Query: 301  NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 360
            NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE
Sbjct: 301  NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 360

Query: 361  EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 420
            EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ
Sbjct: 361  EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 420

Query: 421  GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP 480
            GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP
Sbjct: 421  GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP 480

Query: 481  GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE 540
            GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE
Sbjct: 481  GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE 540

Query: 541  GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC 600
            GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC
Sbjct: 541  GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC 600

Query: 601  SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM 660
            SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM
Sbjct: 601  SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM 660

Query: 661  LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP 720
            LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP
Sbjct: 661  LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP 720

Query: 721  SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF 780
            SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF
Sbjct: 721  SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF 780

Query: 781  APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP 840
            APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP
Sbjct: 781  APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP 840

Query: 841  PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA 900
            PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA
Sbjct: 841  PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA 900

Query: 901  LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP 960
            LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP
Sbjct: 901  LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP 960

Query: 961  EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA 1020
            EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA
Sbjct: 961  EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA 1020

Query: 1021 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGAL 1080
            DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGAL
Sbjct: 1021 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGAL 1080

Query: 1081 EPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHF 1140
            EPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHF
Sbjct: 1081 EPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHF 1140

Query: 1141 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK 1189
            LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK
Sbjct: 1141 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK 1189


>gi|22547207 hairless protein isoform b [Homo sapiens]
          Length = 1134

 Score = 2373 bits (6151), Expect = 0.0
 Identities = 1130/1189 (95%), Positives = 1132/1189 (95%), Gaps = 55/1189 (4%)

Query: 1    MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW 60
            MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW
Sbjct: 1    MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSW 60

Query: 61   LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG 120
            LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG
Sbjct: 61   LPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCG 120

Query: 121  PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP 180
            PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP
Sbjct: 121  PLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWP 180

Query: 181  LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA 240
            LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA
Sbjct: 181  LTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRA 240

Query: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 300
            GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG
Sbjct: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 300

Query: 301  NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 360
            NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE
Sbjct: 301  NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 360

Query: 361  EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 420
            EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ
Sbjct: 361  EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 420

Query: 421  GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP 480
            GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP
Sbjct: 421  GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP 480

Query: 481  GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE 540
            GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE
Sbjct: 481  GLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEE 540

Query: 541  GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC 600
            GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC
Sbjct: 541  GPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCC 600

Query: 601  SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM 660
            SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM
Sbjct: 601  SRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEECTQEAGHAACSLM 660

Query: 661  LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP 720
            LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP
Sbjct: 661  LTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQP 720

Query: 721  SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF 780
            SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF
Sbjct: 721  SCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAF 780

Query: 781  APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP 840
            APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP
Sbjct: 781  APVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP 840

Query: 841  PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA 900
            PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA
Sbjct: 841  PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA 900

Query: 901  LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP 960
            LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP
Sbjct: 901  LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLP 960

Query: 961  EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA 1020
            EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA
Sbjct: 961  EYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHA 1020

Query: 1021 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGAL 1080
            DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQR                
Sbjct: 1021 DTPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQR---------------- 1064

Query: 1081 EPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHF 1140
                         +RR L+                           VQGLVSTVSVTQHF
Sbjct: 1065 -------------IRRFLQ--------------------------MVQGLVSTVSVTQHF 1085

Query: 1141 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK 1189
            LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK
Sbjct: 1086 LSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK 1134


>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
          Length = 2303

 Score =  254 bits (649), Expect = 3e-67
 Identities = 225/764 (29%), Positives = 336/764 (43%), Gaps = 113/764 (14%)

Query: 482  LQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEG 541
            LQD  C  +   L +C+ C     + G    HS    R      L   ++          
Sbjct: 1497 LQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSS 1556

Query: 542  PGSGPDSRLSTGL-------------AKHLLSGLGDRLCRLLRREREALAWAQREGQGPA 588
            P    D  +S                +K++L  +GD+ C+L+  E+ AL+W +++ +  A
Sbjct: 1557 PDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAK-IA 1615

Query: 589  VTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEEC 648
                  G+   C  C   LFN HW C +C   +C+ C +      +R+K  +      +C
Sbjct: 1616 WKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWM---KC 1672

Query: 649  TQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWA---PGDAG 705
             +   H    LM TQ +    L +L  AMH +  K+ I+ HC C     +     P   G
Sbjct: 1673 VKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNG 1732

Query: 706  QQKESTQKTPP--------TPQPSCNGDTHRT----------------KSIKEETPDSAE 741
              +   Q TPP        +P+     D   T                +  +EE  ++ E
Sbjct: 1733 VSQSQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKE 1792

Query: 742  TPAEDRA-------------GR-GPLPCPS------LCELLASTAVKLCLGHERIHMAFA 781
               E++              GR  PL   +      L +LL +TA KL +G     +AFA
Sbjct: 1793 LTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFA 1852

Query: 782  PV----TPALPSDDRITNILDSIIAQVVERKIQEKALG-----PGLRAGP---------- 822
            PV     P+  S   + NILD IIA VVE KI           P L+  P          
Sbjct: 1853 PVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDE 1912

Query: 823  GLRKGLGLPLSPVRPRLPPPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQ 882
              +    +P S +  +      +LWL++ +      + LF+E W+QGQP +VSG+ + + 
Sbjct: 1913 NNKLYSDIPHSWICEK-----HILWLKDYKNSSN--WKLFKECWKQGQPAVVSGVHKKMN 1965

Query: 883  GNLWGTEALGALGGQVQA-LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGS--VLLLH 939
             +LW  E++    G  QA L        S+     FW+GF     R K+  G   VL L 
Sbjct: 1966 ISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLK 2025

Query: 940  RALGDED-----TSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRP-LEPQLWAAYG 993
                 ED      +R E+L  SLPLPEYC   GK NLAS+LP G  +RP L P+L +AYG
Sbjct: 2026 DWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLP-GFFVRPDLGPRLCSAYG 2084

Query: 994  VSPHRGH-LGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDGEGL-------WS 1045
            V   + H +GT NL +EV+D+V+ILV+          ++   L   + E L         
Sbjct: 2085 VVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLK 2144

Query: 1046 PGSQV-STVWHVFRAQDAQRIRRFLQMVCPA-GAGAL---EPGAPGSCYLDAGLRRRLRE 1100
              S++   +WH++  +D  +IR FLQ +    G   L   +P    S Y++  LR+RL E
Sbjct: 2145 DSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLE 2204

Query: 1101 EWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPE 1144
            E+GV   TL+Q  G+A+++PAGA HQVQ   S + VT+ F+SPE
Sbjct: 2205 EYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPE 2248



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 15/32 (46%), Positives = 20/32 (62%)

Query: 359  SEEVNKASGPRACPPSHHTKLKKTWLTRHSEQ 390
            +  V      +   P++HTKLKK WLTRHSE+
Sbjct: 1311 ANSVGNGQASQTSQPNYHTKLKKAWLTRHSEE 1342


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score =  238 bits (606), Expect = 3e-62
 Identities = 227/783 (28%), Positives = 341/783 (43%), Gaps = 133/783 (16%)

Query: 482  LQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEG 541
            LQD  C  +   L +C+ C     + G    HS    R      L   ++          
Sbjct: 1716 LQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSS 1775

Query: 542  PGSGPDSRLSTGL-------------AKHLLSGLGDRLCRLLRREREALAWAQREGQGPA 588
            P    D  +S                +K++L  +GD+ C+L+  E+ AL+W +++ +  A
Sbjct: 1776 PDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAK-IA 1834

Query: 589  VTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEEC 648
                  G+   C  C   LFN HW C +C   +C+ C +      +R+K  +      +C
Sbjct: 1835 WKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWM---KC 1891

Query: 649  TQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRG--HCPCQADARVWA-PGDAG 705
             +   H    LM TQ +    L +L  AMH +  K+ I+   HC  + + +V   P   G
Sbjct: 1892 VKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNG 1951

Query: 706  QQK-----------------ESTQKTPPTPQPSCNGDTHRTKSIKEE---TPDSAETP-- 743
              +                 ES Q+  P P+   NG +     +  +   TP  +++P  
Sbjct: 1952 VSQVLQNVLNHSNKISLCMPESQQQNTP-PKSEKNGGSSPESDVGTDNKLTPPESQSPLH 2010

Query: 744  -----AEDRA-----------------------------GR-GPLPCPS------LCELL 762
                 AE +A                             GR  PL   +      L +LL
Sbjct: 2011 WLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLL 2070

Query: 763  ASTAVKLCLGHERIHMAFAPV----TPALPSDDRITNILDSIIAQVVERKIQEKALG--- 815
             +TA KL +G     +AFAPV     P+  S   + NILD IIA VVE KI         
Sbjct: 2071 TTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKIN 2130

Query: 816  --PGLRAGP----------GLRKGLGLPLSPVRPRLPPPGALLWLQEPQPCPRRGFHLFQ 863
              P L+  P            +    +P S +  +      +LWL++ +      + LF+
Sbjct: 2131 VKPELKEEPEESIISAVDENNKLYSDIPHSWICEK-----HILWLKDYKNSSN--WKLFK 2183

Query: 864  EHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQA-LSPLGPPQPSSLGSTTFWEGFS 922
            E W+QGQP +VSG+ + +  +LW  E++    G  QA L        S+     FW+GF 
Sbjct: 2184 ECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFE 2243

Query: 923  WPELRPKSDEGS--VLLLHRALGDED-----TSRVENLAASLPLPEYCALHGKLNLASYL 975
                R K+  G   VL L      ED      +R E+L  SLPLPEYC   GK NLAS+L
Sbjct: 2244 EVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHL 2303

Query: 976  PPGLALRP-LEPQLWAAYGVSPHRGH-LGTKNLCVEVADLVSILVHADTPLPAWHRAQKD 1033
            P G  +RP L P+L +AYGV   + H +GT NL +EV+D+V+ILV+          ++  
Sbjct: 2304 P-GFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAG 2362

Query: 1034 FLSGLDGEGL-------WSPGSQV-STVWHVFRAQDAQRIRRFLQMVCPA-GAGAL---E 1081
             L   + E L           S++   +WH++  +D  +IR FLQ +    G   L   +
Sbjct: 2363 ILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHD 2422

Query: 1082 PGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFL 1141
            P    S Y++  LR+RL EE+GV   TL+Q  G+A+++PAGA HQVQ   S + VT+ F+
Sbjct: 2423 PIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFV 2482

Query: 1142 SPE 1144
            SPE
Sbjct: 2483 SPE 2485



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 15/32 (46%), Positives = 20/32 (62%)

Query: 359  SEEVNKASGPRACPPSHHTKLKKTWLTRHSEQ 390
            +  V      +   P++HTKLKK WLTRHSE+
Sbjct: 1530 ANSVGNGQASQTSQPNYHTKLKKAWLTRHSEE 1561


>gi|226442779 jumonji domain containing 1A [Homo sapiens]
          Length = 1321

 Score =  228 bits (582), Expect = 2e-59
 Identities = 204/763 (26%), Positives = 332/763 (43%), Gaps = 100/763 (13%)

Query: 467  QKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCA-------QAAGEGGGHACHSQQVRR 519
            +K  Q G+A +QD       C+ + A+L +C+ C        +   +     C     RR
Sbjct: 521  KKLQQSGEAFVQDDS-----CVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRR 575

Query: 520  SPLG--GELQQEEDTATNSSSEEGPGSG-PDSRLSTGL----AKHLLSGLGDRLCRLLRR 572
                  G L+ E     N    E  G   P ++   G+    AK++L+ +GD  C+++  
Sbjct: 576  LQFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVIS 635

Query: 573  EREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTG 632
            E+EA++  +   Q  A      G+   C  C   +FN HW CPRC   +CV C R+    
Sbjct: 636  EKEAMSTIEPHRQ-VAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKN 694

Query: 633  RAREKAGFQEQSAEECTQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPC 692
              ++ A ++  S  +C +   H   +LM TQ +  +AL ++   +H V  K+ I+ +CPC
Sbjct: 695  -CQQGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPC 753

Query: 693  QADARVWAPGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAEDRAGRGP 752
             ++ +         +++  Q +    +P+      +  S+ E      E  ++      P
Sbjct: 754  -SNRQFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAVGGEAASKPAGSMKP 812

Query: 753  LPCPS-------LCELLASTAVKLCLGHE------RIHMAFAPVTPALPSDDRITNILDS 799
              CP+       L +L +    K     +      +  +   P  P L     + +  +S
Sbjct: 813  A-CPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNS 871

Query: 800  IIAQVVE-------RKIQEKALGP---GLRAGPGL------------------RKGLGLP 831
             I   V        R +   + G    GL+  P +                  ++  GL 
Sbjct: 872  TILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTTSDLSKRPQGLT 931

Query: 832  LSPVRPRLPPP------GALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNL 885
            + P       P        LL LQ+P    +  +++F+E W+QGQPV+VSG+   L   L
Sbjct: 932  IKPSILGFDTPHYWLCDNRLLCLQDPNN--KSNWNVFRECWKQGQPVMVSGVHHKLNSEL 989

Query: 886  WGTEALGALGGQVQALSPLGPPQPSSLGSTT--FWEGFSWPELRPKSD-EGSVLLLHRAL 942
            W  E+     G+ +             G+T   FW+GF     R K++ E  VL L    
Sbjct: 990  WKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEPMVLKLKDWP 1049

Query: 943  GDED-----TSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRPLEPQLWAAYG-VSP 996
              ED      SR ++L A++PLPEY    GKLNLAS LP       L P+++ AYG ++P
Sbjct: 1050 PGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITP 1109

Query: 997  HRGHLGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDG-----------EGLWS 1045
                 GT NL ++V+D  +++V+   P     + ++   +  DG           EG   
Sbjct: 1110 EDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLKTIQDGDSDELTIKRFIEGKEK 1169

Query: 1046 PGSQVSTVWHVFRAQDAQRIRRFLQMVCPA----GAGALEPGAPGSCYLDAGLRRRLREE 1101
            PG+    +WH++ A+D ++IR FL+ V            +P    S YLD  LR+RL +E
Sbjct: 1170 PGA----LWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSLRKRLHQE 1225

Query: 1102 WGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPE 1144
            +GV  W ++Q  G+ V +PAGAPHQV  L S + V + F+SPE
Sbjct: 1226 YGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPE 1268


>gi|20357522 jumonji domain containing 1A [Homo sapiens]
          Length = 1321

 Score =  228 bits (582), Expect = 2e-59
 Identities = 204/763 (26%), Positives = 332/763 (43%), Gaps = 100/763 (13%)

Query: 467  QKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCA-------QAAGEGGGHACHSQQVRR 519
            +K  Q G+A +QD       C+ + A+L +C+ C        +   +     C     RR
Sbjct: 521  KKLQQSGEAFVQDDS-----CVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRR 575

Query: 520  SPLG--GELQQEEDTATNSSSEEGPGSG-PDSRLSTGL----AKHLLSGLGDRLCRLLRR 572
                  G L+ E     N    E  G   P ++   G+    AK++L+ +GD  C+++  
Sbjct: 576  LQFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVIS 635

Query: 573  EREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTG 632
            E+EA++  +   Q  A      G+   C  C   +FN HW CPRC   +CV C R+    
Sbjct: 636  EKEAMSTIEPHRQ-VAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKN 694

Query: 633  RAREKAGFQEQSAEECTQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPC 692
              ++ A ++  S  +C +   H   +LM TQ +  +AL ++   +H V  K+ I+ +CPC
Sbjct: 695  -CQQGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPC 753

Query: 693  QADARVWAPGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAEDRAGRGP 752
             ++ +         +++  Q +    +P+      +  S+ E      E  ++      P
Sbjct: 754  -SNRQFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAVGGEAASKPAGSMKP 812

Query: 753  LPCPS-------LCELLASTAVKLCLGHE------RIHMAFAPVTPALPSDDRITNILDS 799
              CP+       L +L +    K     +      +  +   P  P L     + +  +S
Sbjct: 813  A-CPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNS 871

Query: 800  IIAQVVE-------RKIQEKALGP---GLRAGPGL------------------RKGLGLP 831
             I   V        R +   + G    GL+  P +                  ++  GL 
Sbjct: 872  TILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTTSDLSKRPQGLT 931

Query: 832  LSPVRPRLPPP------GALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNL 885
            + P       P        LL LQ+P    +  +++F+E W+QGQPV+VSG+   L   L
Sbjct: 932  IKPSILGFDTPHYWLCDNRLLCLQDPNN--KSNWNVFRECWKQGQPVMVSGVHHKLNSEL 989

Query: 886  WGTEALGALGGQVQALSPLGPPQPSSLGSTT--FWEGFSWPELRPKSD-EGSVLLLHRAL 942
            W  E+     G+ +             G+T   FW+GF     R K++ E  VL L    
Sbjct: 990  WKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEPMVLKLKDWP 1049

Query: 943  GDED-----TSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRPLEPQLWAAYG-VSP 996
              ED      SR ++L A++PLPEY    GKLNLAS LP       L P+++ AYG ++P
Sbjct: 1050 PGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITP 1109

Query: 997  HRGHLGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDG-----------EGLWS 1045
                 GT NL ++V+D  +++V+   P     + ++   +  DG           EG   
Sbjct: 1110 EDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLKTIQDGDSDELTIKRFIEGKEK 1169

Query: 1046 PGSQVSTVWHVFRAQDAQRIRRFLQMVCPA----GAGALEPGAPGSCYLDAGLRRRLREE 1101
            PG+    +WH++ A+D ++IR FL+ V            +P    S YLD  LR+RL +E
Sbjct: 1170 PGA----LWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSLRKRLHQE 1225

Query: 1102 WGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPE 1144
            +GV  W ++Q  G+ V +PAGAPHQV  L S + V + F+SPE
Sbjct: 1226 YGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPE 1268


>gi|38372909 jumonji domain containing 1B [Homo sapiens]
          Length = 1761

 Score =  175 bits (443), Expect = 3e-43
 Identities = 139/440 (31%), Positives = 212/440 (48%), Gaps = 39/440 (8%)

Query: 780  FAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLR--KGLGLPLSPVRP 837
            F+  +  + S   + N LD IIA VVE K    A           +  K + + L+ + P
Sbjct: 1319 FSTSSAGVKSKASLPNFLDHIIASVVENKKTSDASKRACNLTDTQKEVKEMVMGLNVLDP 1378

Query: 838  RLPPP----GALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGA 893
                     G LL L +P    +  + +F+E W+QGQPVLVSG+ + L+  LW  EA   
Sbjct: 1379 HTSHSWLCDGRLLCLHDPSN--KNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSQ 1436

Query: 894  LGGQ--VQALSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLH-------RALGD 944
              G   V  ++       S +    FW+GF     R +S++G  ++L            D
Sbjct: 1437 EFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRD 1496

Query: 945  EDTSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRPLEPQLWAAYG-VSPHRGHLGT 1003
               +R E+L  +LPLPEY    G+LNLAS LP       L P+++ AYG ++     +GT
Sbjct: 1497 MMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGT 1556

Query: 1004 KNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDGE-----------GLWSPGSQVST 1052
             NL ++V+D V+++V+   P+      ++   +  +G+           G   PG+    
Sbjct: 1557 TNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTKQRIHDGKEKPGA---- 1612

Query: 1053 VWHVFRAQDAQRIRRFLQMVCPAGAGALEPGAPG----SCYLDAGLRRRLREEWGVSCWT 1108
            +WH++ A+DA++IR  L+ V         P        S YLD  LR+RL EE+GV  W 
Sbjct: 1613 LWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWA 1672

Query: 1109 LLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPETSALSAQLCHQGPSL--PPDCHLL 1166
            ++Q  G+AV +PAGAPHQV  L S + V + F+SPE      +L  +   L      H  
Sbjct: 1673 IVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHED 1732

Query: 1167 YAQMDWAVFQAVKVAVGTLQ 1186
              Q+   ++ AVK AVGTL+
Sbjct: 1733 KLQVKNIIYHAVKDAVGTLK 1752



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 83/330 (25%), Positives = 134/330 (40%), Gaps = 45/330 (13%)

Query: 384  LTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGA 443
            L+   EQ +   G   + E  + +L      G    +  +G    K+ P   P TA    
Sbjct: 821  LSDSEEQLQAKTGLKGIPEHLMGKLGP---NGERSAELLLGKSKGKQAPKGRPRTAPLKV 877

Query: 444  GGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCA-- 501
            G  Q V       KDV   +  +Q G         +P LQD  C+ +   L +C+ C   
Sbjct: 878  G--QSVL------KDVSKVKKLKQSG---------EPFLQDGSCINVAPHLHKCRECRLE 920

Query: 502  ------QAAGEGGGHACHSQQVRRSPLG--GELQQEEDTATNSSSEEGPGSG-PDSRLST 552
                  +   +    AC     RR      G L+ E   +   S  +      P S L+ 
Sbjct: 921  RYRKFKEQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMNLWIPSSSLAE 980

Query: 553  GL----AKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLF 608
            G+    +K++L+ +GD+ C+L+  E+EA+   +   Q  A      G+   C  C   LF
Sbjct: 981  GIDLETSKYILANVGDQFCQLVMSEKEAMMMVEPH-QKVAWKRAVRGVREMCDVCETTLF 1039

Query: 609  NTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEE------CTQEAGHAACSLMLT 662
            N HW C +C   +C+ C R+    ++R ++  +E   EE      C +   H   +LM T
Sbjct: 1040 NIHWVCRKCGFGVCLDCYRLR---KSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPT 1096

Query: 663  QFVSSQALAELSTAMHQVWVKFDIRGHCPC 692
            Q +   AL  +   +H    K+ I+ +CPC
Sbjct: 1097 QIIPGTALYNIGDMVHAARGKWGIKANCPC 1126


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 70/235 (29%), Positives = 84/235 (35%), Gaps = 54/235 (22%)

Query: 275 PWTSWPACPPGLVHTLGNVWAGPGD-GNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPT 333
           P  + P  PPG   T G+    PG  G+ GYQ GPP  P    P           S PP 
Sbjct: 173 PGPAGPPGPPGPPGTSGH----PGSPGSPGYQ-GPPGEPGQAGP-----------SGPPG 216

Query: 334 KGGGLGPCGKCQEGLEGGASGASEPSEE----VNKASGPRACPPSHHTKLKKTWLTRHSE 389
             G +GP G   +  E G  G   P E          GP   P     K  + +  R+ E
Sbjct: 217 PPGAIGPSGPAGKDGESGRPG--RPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGE 274

Query: 390 QFEC----------------------PRGCPEVEERPVARLRALKRAGSPEVQGAMGSPA 427
           + E                       PRG P    RP     A  R G+   +G+ G P 
Sbjct: 275 KGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGAR-GNDGARGSDGQPG 333

Query: 428 PKRPPDP--FPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDP 480
           P  PP    FPG+   GA G  EV        +   GQ  E  GPQ G A  Q P
Sbjct: 334 PPGPPGTAGFPGS--PGAKG--EVGPAGSPGSNGAPGQRGE-PGPQ-GHAGAQGP 382



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 145/581 (24%), Positives = 173/581 (29%), Gaps = 141/581 (24%)

Query: 12  PTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPA-------------PFWRGVLSTPD 58
           P  E+ AP     R   G P RDG+  GP   G P              P  +G    P 
Sbjct: 505 PAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPG 564

Query: 59  SWLPPGFPQGPKDMLPLVEGEGPQ--------NGERKVNWLGSKEGLRWKEAMLTHPLAF 110
              PPG P GP+    ++   GP+        NGER        +G   K          
Sbjct: 565 ---PPG-PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET------ 614

Query: 111 CGPACPPRCGPLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSG 170
            GP  PP  GP  P    G   + P                             P  + G
Sbjct: 615 -GPQGPP--GPTGPGGDKGD--TGPPG---------------------------PQGLQG 642

Query: 171 LP----PEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEP 226
           LP    P      P  P P     G P  P     G KG    D   P     P  A  P
Sbjct: 643 LPGTGGPPGENGKPGEPGP-KGDAGAPGAP-----GGKG----DAGAPGERGPPGLAGAP 692

Query: 227 GLFG----------LNSGGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQP----- 271
           GL G            + G     G A  P L    GE G      P     G+P     
Sbjct: 693 GLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKG-DKGEPGGPGA 751

Query: 272 DTVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCC---- 327
           D VP    P  P G +   G     PGD   G   G P  P    P     +RG      
Sbjct: 752 DGVPGKDGPRGPTGPIGPPGPA-GQPGDKGEG---GAPGLPGIAGPRGSPGERGETGPPG 807

Query: 328 -SSYPPTKGGGLGPCGKCQEGL-----EGGASGASEPSEEVNKASGPRACPPSHHTKLKK 381
            + +P   G    P GK + G      EGG  G + P       SGP   P     K + 
Sbjct: 808 PAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG----GSGPAGPPGPQGVKGE- 862

Query: 382 TWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQ 441
               R S       G P     P          G+P   G  GSP    PP P   T   
Sbjct: 863 ----RGSPGGPGAAGFPGARGLPGPP----GSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914

Query: 442 GAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCA 501
           G+ G        +     D+GQ  E KG          PG Q  P    P  +A      
Sbjct: 915 GSPG--------VSGPKGDAGQPGE-KG---------SPGAQGPPGAPGPLGIA---GIT 953

Query: 502 QAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEGP 542
            A G  G       +    P G + +  +  A   S E GP
Sbjct: 954 GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP 994



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 59/227 (25%), Positives = 75/227 (33%), Gaps = 37/227 (16%)

Query: 223  AAEPGLFG-LNSGGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPA 281
            A  PG+ G   S G     GE+ +P  +   GE G    Q       G P        P 
Sbjct: 959  AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQ-------GLPGLAGTAGEPG 1011

Query: 282  CP--PGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPS-PEPPVTQRGCCSSYPPTKGGGL 338
                PG     G   +  G G+ G + G P  P  P  P PP               G +
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRG-ENGSPGAPGAPGHPGPP---------------GPV 1055

Query: 339  GPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCP 398
            GP GK  +  E G +G   P+     A    A  P      K     R +   +  RG P
Sbjct: 1056 GPAGKSGDRGESGPAG---PAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP 1112

Query: 399  EVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGG 445
                 P +        G    QGA+GSP P  P  P   +   G  G
Sbjct: 1113 GNPGAPGS-------PGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG 1152



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 68/268 (25%), Positives = 86/268 (32%), Gaps = 58/268 (21%)

Query: 223 AAEPGLFGLNSG-GHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDT--VPWTSW 279
           A EPG  G     G     GEA  P +    GE   G+  +P     G+P    +P  + 
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGE--DGKDGSP-----GEPGANGLPGAAG 483

Query: 280 PACPPGLVHTLGNVWAGP-GDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGL 338
               PG        + GP G   +  + GP      P P  P   RG     P   G   
Sbjct: 484 ERGAPG--------FRGPAGPNGIPGEKGPAGERGAPGPAGP---RGAAGE-PGRDGVPG 531

Query: 339 GPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCP 398
           GP  +   G  GG     +P    ++    R  PP                    PRG P
Sbjct: 532 GPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG----------------PRGQP 575

Query: 399 EVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKD 458
            V   P  +       G    +G  G P P+ PP     T  QG  G      T  G   
Sbjct: 576 GVMGFPGPKGND-GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG-----PTGPGGDK 629

Query: 459 VDSGQHDEQKGPQDGQASLQDPGLQDIP 486
            D+G      GPQ         GLQ +P
Sbjct: 630 GDTG----PPGPQ---------GLQGLP 644


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 58/199 (29%), Positives = 77/199 (38%), Gaps = 35/199 (17%)

Query: 151  ILERAPFWVPTCLPPYLVSGL--PPEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYY 208
            I + A F  P  L P L S    PP   C  P  P P   S G     +A ++   G ++
Sbjct: 859  IQQLAGFSAPAGLSPLLPSSSSSPPPGACGSPSAPTP---SAGV----AATTIAGFGHFH 911

Query: 209  KDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFL 268
            K      L     ++  P L  L  G    R+ +A +PS        G G  ++    FL
Sbjct: 912  K-----ALGGSLSSSDSPLLTPLQPGA---RSPQAAQPSPAPPGARGGLGLPEH----FL 959

Query: 269  GQPDTVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCP--SPEPPVTQRGC 326
              P   P +  P+  PG       +   PG+ +LG   GP +TP  P   PEPP    G 
Sbjct: 960  PPP---PSSRSPSSSPG------QLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGA 1010

Query: 327  CSSYPP---TKGGGLGPCG 342
                 P   T  GGL P G
Sbjct: 1011 SGGASPVGFTPRGGLSPPG 1029


>gi|156938257 leucine rich repeat containing 16B [Homo sapiens]
          Length = 1372

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 56/228 (24%), Positives = 76/228 (33%), Gaps = 42/228 (18%)

Query: 296  GPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQE------GLE 349
            GPG    G  L PP       P PP TQ    S  PP+ G    PC   +E      G  
Sbjct: 1069 GPGSPTTGLLLPPP-------PPPPPTQESPPSPDPPSLGNNSSPCWSPEEESSLLPGFG 1121

Query: 350  GG---------ASGASEPSEEVNKASGPRACPPSHHTKL-----KKTWLTRHSEQFECPR 395
            GG          +  SEP E    A G    P  H   L      K W       F+  R
Sbjct: 1122 GGRGPSFRRKMGTEGSEPGEG-GPAPGTAQQPRVHGVALPGLERAKGW------SFDGKR 1174

Query: 396  GCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIG 455
              P  ++    +    +R+      G+   P P +   P      +    W  + + S  
Sbjct: 1175 EGPGPDQEGSTQAWQKRRSSDDAGPGSWKPPPPPQSTKPSFSAMRRAEATW-HIAEESAP 1233

Query: 456  NKDVDSGQHDEQKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCAQA 503
            N    S     Q G ++ + +L        P   LPA+ A+ Q  A A
Sbjct: 1234 NHSCQSPSPASQDGEEEKEGTL-------FPERTLPARNAKLQDPALA 1274


>gi|116734704 interferon regulatory factor 2 binding protein 2
           isoform A [Homo sapiens]
          Length = 587

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/230 (25%), Positives = 79/230 (34%), Gaps = 47/230 (20%)

Query: 403 RPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSG 462
           + VAR  A KR  SPE +G +G P       P+  T+ +G         + +      + 
Sbjct: 348 KAVART-ARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTAS 406

Query: 463 QHDEQKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPL 522
            H  +  P +   + Q P    +  L L A  A           GG HA           
Sbjct: 407 PHSNRTTPPEAAQNGQSP----MAALILVADNA-----------GGSHASKDAN------ 445

Query: 523 GGELQQEEDTATNSSSEEGPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQR 582
               Q    T  NS+S   P S    RL        + G G            A      
Sbjct: 446 ----QVHSTTRRNSNSPPSPSSMNQRRLGP----REVGGQG------------AGNTGGL 485

Query: 583 EGQGPAVTEDSP---GIPRCCSRCHHGLFNTHW-RCPRC-SHRLCVACGR 627
           E   PA   DS      P CC+ CH  L +TH+ +CP   SH+ C  C R
Sbjct: 486 EPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSR 535


>gi|148612825 Rap GTPase interactor [Homo sapiens]
          Length = 1075

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 21/150 (14%)

Query: 236 HLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTS--WPACPPGLVHTLGNV 293
           H+   G  E PS         A R   P    +    T+P     W   PPG   + G  
Sbjct: 837 HVVLDGHLEAPSCPL------APRDPGPAAREVAPERTLPLRGAPWAQAPPGRQPSRGGS 890

Query: 294 WAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKC-QEGLEGGA 352
            AGP   +    L PP+TP  P P  P         +P +     GPCGK   E    G 
Sbjct: 891 QAGPPHTDSSCLLTPPSTPLGPEPGDP--------DWPESG----GPCGKALPERQRNGL 938

Query: 353 SGASEPSEEVNKASGPRACPPSHHTKLKKT 382
           SG    + E + A+     PP+  ++   T
Sbjct: 939 SGLRGAAPEGDSAALAEESPPAPSSRSSST 968


>gi|116734706 interferon regulatory factor 2 binding protein 2
           isoform B [Homo sapiens]
          Length = 571

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 56/223 (25%), Positives = 75/223 (33%), Gaps = 46/223 (20%)

Query: 410 ALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKG 469
           A KR  SPE +G +G P       P+  T+ +G         + +      +  H  +  
Sbjct: 338 ARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTT 397

Query: 470 PQDGQASLQDPGLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQE 529
           P +   + Q P    +  L L A  A           GG HA               Q  
Sbjct: 398 PPEAAQNGQSP----MAALILVADNA-----------GGSHASKDAN----------QVH 432

Query: 530 EDTATNSSSEEGPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAV 589
             T  NS+S   P S    RL        + G G            A      E   PA 
Sbjct: 433 STTRRNSNSPPSPSSMNQRRLGP----REVGGQG------------AGNTGGLEPVHPAS 476

Query: 590 TEDSP---GIPRCCSRCHHGLFNTHW-RCPRC-SHRLCVACGR 627
             DS      P CC+ CH  L +TH+ +CP   SH+ C  C R
Sbjct: 477 LPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSR 519


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 79/284 (27%), Positives = 97/284 (34%), Gaps = 61/284 (21%)

Query: 190  GGQPKVPSAFSLGSKGFYYKD--PSIPRLAKEPLAAAEPGLFGLNSGGHLQRAGEAERPS 247
            G Q    SA + G +GF   D  P  P  A  P     PGL G  S G     G+     
Sbjct: 1284 GPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKG--SPGLPGPRGDPGERG 1341

Query: 248  LHQRDGEMGA-------------GRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTL--GN 292
                 GE GA             GR+ +P P     P        P  PPGL  T   G+
Sbjct: 1342 PRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGD 1401

Query: 293  VW-------AGPGDGNLGY-QLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKC 344
                      GPG+G +   + G P  P  P P+ PV         PP   G  G  G  
Sbjct: 1402 KGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVG--------PP---GKKGEKGDS 1450

Query: 345  QEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTW---LTRHSEQFECPRGCPEVE 401
            ++G  G       P E+     GPR  P +   K  + +   L    E+ E  RG P   
Sbjct: 1451 EDGAPGLPGQPGSPGEQ-----GPRGPPGAIGPKGDRGFPGPLGEAGEKGE--RGPPGP- 1502

Query: 402  ERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGG 445
                        AGS  + G  G P  K P  P   T  QG  G
Sbjct: 1503 ------------AGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKG 1534



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 56/215 (26%), Positives = 76/215 (35%), Gaps = 27/215 (12%)

Query: 276  WTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKG 335
            +T+ P   P  V+        PG+  L  Q+GPP  P  P        +G   S    KG
Sbjct: 1238 FTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGS-ATAKG 1296

Query: 336  GGLGPCGKCQEGLEGGASGASEPSEEVNKAS----GPRACPPSHHTKLKKTWLTRHSEQF 391
                P    + G  G A     P     K S    GPR  P                   
Sbjct: 1297 ERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERG--------------- 1341

Query: 392  ECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRD 451
              PRG P+ E  P A  + +   G P + G  G P P  PP P     + G  G   +  
Sbjct: 1342 --PRG-PKGE--PGAPGQVIGGEG-PGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG 1395

Query: 452  TSIGNKDVDSGQHDEQKGPQDGQASLQDPGLQDIP 486
            T++     D G+     GP +G  +  +PGL  +P
Sbjct: 1396 TAMKGDKGDRGERG-PPGPGEGGIAPGEPGLPGLP 1429


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
           sapiens]
          Length = 1691

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 80/314 (25%), Positives = 99/314 (31%), Gaps = 56/314 (17%)

Query: 162 CLPPYLVSGLPPEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFY-YKDPSIPRLAKEP 220
           C P     G P       P  P  +  S G   +      G +GF     P  P+  K P
Sbjct: 42  CFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLK-----GERGFPGLLGPYGPKGDKGP 96

Query: 221 LAAAEPGLFGLNS-GGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSW 279
           +    PG  G+N   GH  + G    P L   +G  GA        +    PD  P    
Sbjct: 97  MGV--PGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGA--------VGFPGPDGYPGLLG 146

Query: 280 PACPPGLVHTLGNVWAGPG--------------DGNLGYQLGPPATPRCPSPEPPVTQRG 325
           P   PG   + G+    PG              DG  G Q G P  P    P  P   +G
Sbjct: 147 PPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ-GAPGFPGAVGPAGPPGLQG 205

Query: 326 CCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPS-------HHTK 378
                PP   G LGP G    G +G      +         GP   PPS          K
Sbjct: 206 -----PPGPPGPLGPDGNMGLGFQGEKGVKGDVG-----LPGPAGPPPSTGELEFMGFPK 255

Query: 379 LKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGT 438
            KK      S+    P+G P +   P      L   G    +G  G P    P  P    
Sbjct: 256 GKK-----GSKGEPGPKGFPGISGPP--GFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSE 308

Query: 439 AEQGAGGWQEVRDT 452
             QG  G Q  + T
Sbjct: 309 GVQGPPGQQGKKGT 322


>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
          Length = 1374

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 68/288 (23%), Positives = 101/288 (35%), Gaps = 39/288 (13%)

Query: 308 PPATPRCPSPEP-------------PVTQRGCCSSYP---PTKGGGLGPCGKCQEGLEGG 351
           P  TPR  SPEP                + GCC   P     +G    PC       E  
Sbjct: 711 PKQTPRA-SPEPGYPGEPLLGLQAASAQEPGCCPGLPHLCSAQGLAPAPCLVTPSWTETA 769

Query: 352 ASGASEPSEEVNKAS------GPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPV 405
           +SG   P  E   A+      GPR   PS  +  ++      SE+   P     + + P 
Sbjct: 770 SSGGDHPQAEPKLATEAEGTTGPRLPLPSVPSPSQEG-APLPSEEASAPDAPDALPDSPT 828

Query: 406 ----ARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDS 461
                 + A+K A +  + G+  SP  + P      TAE  +G + +     +  +  D 
Sbjct: 829 PATGGEVSAIKLASA--LNGSSSSPEVEAPSSEDEDTAEATSGIFTDTSSDGLQARRPDV 886

Query: 462 ----GQHDEQKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQV 517
                   +Q G  D   SL  P         + +  A   S  Q      G+   + + 
Sbjct: 887 VPAFRSLQKQVGTPDSLDSLDIPSSASDGGYEVFSPSATGPSGGQPRALDSGYDTENYES 946

Query: 518 RRSPLGGELQQEEDTATNSSSEEGPGSGPDSRLSTGLAKHLLSGLGDR 565
               L    +  E  A    + EG G GP++RLST      LSGL ++
Sbjct: 947 PEFVLKEAQEGCEPQAFAELASEGEGPGPETRLSTS-----LSGLNEK 989


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 112/422 (26%), Positives = 145/422 (34%), Gaps = 64/422 (15%)

Query: 28  PGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSWLPPGFPQG-PKDMLPLVEGEGPQNGER 86
           P  PPRDG    P      AP   G LS+P   L  GFP   P D+L + E     N E 
Sbjct: 451 PPPPPRDGPFPWPWPPAHSAPR-PGTLSSPFPLLD-GFPGADPDDVLTVTESSRGLNLE- 507

Query: 87  KVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCGPLMPEHSGGHLKSDPVAFRPWHCPFL 146
                       W++A          PA  P   P  P     H       +     P +
Sbjct: 508 ----------CLWEKARRGAGRGGGAPAWQPASAPPAP-----HANPSNPFYEALSTPSV 552

Query: 147 LETKILERAPFWVPTCLPPYLVSGLPPE--HPCDW-PLTPHPWVYSGGQPKVPSAF-SLG 202
           L   I  R+P             G PPE   P DW PL P   V +   P+ PS    L 
Sbjct: 553 LPV-ISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPG--VPAPQAPQAPSEVPQLV 609

Query: 203 SKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQN 262
           S+   +  P  P     P  ++  G F L SG   +  G           GE  AG   +
Sbjct: 610 SET--WASPLFPAPRPFPAQSSASGSF-LLSGWDPEGRGA----------GETLAG---D 653

Query: 263 PCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVT 322
           P  + LG+  T PW          V        G   G     LG   + R P P P  +
Sbjct: 654 PAEV-LGERGTAPW----------VEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCS 702

Query: 323 QRGCCSSYPPTKGGGLG-----PCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHT 377
           + G CS  P  +G  +      P   C    E     +S  +E  + A  P A P S   
Sbjct: 703 REGACSCLPLERGDAVAGWGGHPALGCPHPPE---DDSSLRAERGSLADLPMAPPASAPP 759

Query: 378 KLKKTWLTRHSEQFECPRGCPEVEERPVARLRA-LKRAGSPEVQGAMGSP-APKRPPDPF 435
           +     +   + Q+   RG P     P    RA    A SP+   A+ SP +    P P 
Sbjct: 760 EFLDPLMGAAAPQYP-GRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPK 818

Query: 436 PG 437
           PG
Sbjct: 819 PG 820



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 39/170 (22%), Positives = 55/170 (32%), Gaps = 16/170 (9%)

Query: 309  PATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGP 368
            P  P  P P PP  Q       PP     + P G      E GA  +    +      G 
Sbjct: 1172 PQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEG------EPGAPDSRAGGDTALSGDGD 1225

Query: 369  RACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAP 428
               P     ++ + +L     Q           E+  ARL  L  A  P        P P
Sbjct: 1226 PPKPERKGPEMPRLFLDLGPPQGN--------SEQIKARLSRLSLALPPLTLTPFPGPGP 1277

Query: 429  KRPP--DPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQAS 476
            +RPP      G A   AGG           +D D  + ++++    G A+
Sbjct: 1278 RRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAA 1327


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
           sapiens]
          Length = 1690

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 80/314 (25%), Positives = 99/314 (31%), Gaps = 56/314 (17%)

Query: 162 CLPPYLVSGLPPEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFY-YKDPSIPRLAKEP 220
           C P     G P       P  P  +  S G   +      G +GF     P  P+  K P
Sbjct: 41  CFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLK-----GERGFPGLLGPYGPKGDKGP 95

Query: 221 LAAAEPGLFGLNS-GGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSW 279
           +    PG  G+N   GH  + G    P L   +G  GA        +    PD  P    
Sbjct: 96  MGV--PGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGA--------VGFPGPDGYPGLLG 145

Query: 280 PACPPGLVHTLGNVWAGPG--------------DGNLGYQLGPPATPRCPSPEPPVTQRG 325
           P   PG   + G+    PG              DG  G Q G P  P    P  P   +G
Sbjct: 146 PPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ-GAPGFPGAVGPAGPPGLQG 204

Query: 326 CCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPS-------HHTK 378
                PP   G LGP G    G +G      +         GP   PPS          K
Sbjct: 205 -----PPGPPGPLGPDGNMGLGFQGEKGVKGDVG-----LPGPAGPPPSTGELEFMGFPK 254

Query: 379 LKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGT 438
            KK      S+    P+G P +   P      L   G    +G  G P    P  P    
Sbjct: 255 GKK-----GSKGEPGPKGFPGISGPP--GFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSE 307

Query: 439 AEQGAGGWQEVRDT 452
             QG  G Q  + T
Sbjct: 308 GVQGPPGQQGKKGT 321


>gi|31442420 shroom family member 1 [Homo sapiens]
          Length = 847

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 44/159 (27%), Positives = 55/159 (34%), Gaps = 21/159 (13%)

Query: 293 VWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGL---- 348
           VW GPG         PP    C SP P           P    G  GP  +    L    
Sbjct: 66  VWGGPGPA-------PPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYAL 118

Query: 349 ----EGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECP-RGCPEVEER 403
               E  A     PS   ++A+  +    +    L++T   R   +   P R  P V  R
Sbjct: 119 AAEAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPAR 178

Query: 404 PVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQG 442
           P A      R+ S    G  G PA  R   P PGTA +G
Sbjct: 179 PPA---THPRSASLSHPGGEGEPARSRA--PAPGTAGRG 212


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 92/374 (24%), Positives = 121/374 (32%), Gaps = 85/374 (22%)

Query: 172  PPE-HPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYYK------DPSIPRLA---KEPL 221
            PPE HP   P +P P   +     V    ++G  G           P    LA   + P 
Sbjct: 1023 PPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPG 1082

Query: 222  AAAEPGLFGLNSGGHLQRAGEA------ERPSLHQRDGEMGAGR-------QQNPCPLFL 268
             +A+PG F  +  G  +  G +      E P L + +      R       QQ      L
Sbjct: 1083 ESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFIL 1142

Query: 269  GQPDTVPWT-------SWPACPPGLV---HTLGNVWAGPGDGNLGYQLGPPATPRCPSP- 317
             + DTV          + P  PP L    +  G V   P       Q GPP  P  P P 
Sbjct: 1143 TESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASE----QAGPPELPPPPPPA 1198

Query: 318  EPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHT 377
            EPP T        PP +G                         E  K + P   P     
Sbjct: 1199 EPPPTDLAHLPPLPPPEG-------------------------EARKPAKPPVSP----- 1228

Query: 378  KLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPG 437
               K  LT+   + +   G P     P ++   L   GSPEV+ A G+P P  P  P P 
Sbjct: 1229 ---KPVLTQPVPKLQ---GSPT----PTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPP 1278

Query: 438  TAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKG-------PQDGQASLQDPGLQDIPCLAL 490
            TA +       +   S G     S               P    AS   P     P L +
Sbjct: 1279 TAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHV 1338

Query: 491  PAKLAQCQSCAQAA 504
            PAK  +  + A AA
Sbjct: 1339 PAKPPRAAAAAAAA 1352


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 94/352 (26%), Positives = 114/352 (32%), Gaps = 64/352 (18%)

Query: 104 LTHPLAFCGPACPPR--------CGPLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERA 155
           L+H  A   P  PPR          PL P  SG    + P      H P       +  A
Sbjct: 654 LSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPA 713

Query: 156 P--FWVPTCLPPYLVSGLPPEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSI 213
           P   W     PP     + PE P D    P P     G  +  +AF     GF    P  
Sbjct: 714 PQASWWAFVEPP----AVSPEVPPDLLAFPGPRPSFRGSRRRGAAF-----GFPGASPRA 764

Query: 214 PRL-AKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPD 272
            R  A  PLA+ +P L      G+         P L  R G                QP 
Sbjct: 765 SRRRAWSPLASPQPSLRSSPGLGYCSPLAPPS-PQLSLRTGPF--------------QPP 809

Query: 273 TVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPP 332
            +P    PA  P       ++   P       +LGPP +P   SP PP    G C S  P
Sbjct: 810 FLP----PARRPR------SLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHS--P 857

Query: 333 TKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFE 392
            +     P       L       SEP     +A  P+   P H       W     E  E
Sbjct: 858 RRSSLNLP-----SRLPHTWRRLSEPP---TRAVKPQVRLPFHRPPRAGAW-RAPLEHRE 908

Query: 393 CPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAG 444
            PR  PE  E P         A S +V      P  +RPP P+PG A    G
Sbjct: 909 SPRE-PEDSETP---WTVPPLAPSWDVD----MPPTQRPPSPWPGGAGSRRG 952


>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
           sapiens]
          Length = 584

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 13/129 (10%)

Query: 507 GGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEGPGSGPDSRLSTGLAKHLLSGLGDRL 566
           GG ++  +  V  SP+   L+   +   +S  + G G GP   +  G A    S      
Sbjct: 409 GGPYSAETPGVP-SPIAA-LKNVAEALGHSPKDPGGGGGP---VRAGGASPAASSTAQPP 463

Query: 567 C--RLLRREREA----LAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHW-RCPRC-S 618
              RL+ R  EA     A A+    G + T  +PG P CC+ C   L +TH+ +CP    
Sbjct: 464 TQHRLVARNGEAEVSPTAGAEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPG 523

Query: 619 HRLCVACGR 627
           H+ C  C R
Sbjct: 524 HKFCFPCSR 532


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 40.4 bits (93), Expect = 0.010
 Identities = 68/241 (28%), Positives = 81/241 (33%), Gaps = 36/241 (14%)

Query: 225 EPGLFGLNSGGHLQRAGEAERPSLHQRDGEMG----AGRQQNPCPL----FLGQPDTVPW 276
           EPG  G++  G +   G    P     DGE G    AG +  P P     F G P  +P 
Sbjct: 229 EPGEPGVS--GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPG-LPG 285

Query: 277 TSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGG 336
                  PGL    G   A    G    + G P     P P  P   RG      P + G
Sbjct: 286 VKGHRGYPGLDGAKGEAGAPGVKG----ESGSPGENGSPGPMGP---RGL-----PGERG 333

Query: 337 GLGPCGKCQEGLEGGASGASEPSEEVNKASGPR-ACPPSHHTKLKKTWLTRHSEQFECPR 395
             GP G        G  G + P   V  A GP     P    +   T   R  E  + PR
Sbjct: 334 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG-ARGPEGAQGPR 392

Query: 396 GCPEVEERPVARLR-----------ALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAG 444
           G P     P                A   AG+P + GA G P P+ PP P   T   G  
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452

Query: 445 G 445
           G
Sbjct: 453 G 453



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 62/246 (25%), Positives = 80/246 (32%), Gaps = 37/246 (15%)

Query: 202 GSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQ 261
           G++GF    P  P L         PGL G          GEA  P +    G  G    +
Sbjct: 273 GARGF----PGTPGLPGVKGHRGYPGLDGAK--------GEAGAPGVKGESGSPG----E 316

Query: 262 NPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPV 321
           N  P  +G P  +P       P G     GN    PG       +GP   P  P      
Sbjct: 317 NGSPGPMG-PRGLPGERGRTGPAGAAGARGND-GQPGPAGPPGPVGPAGGPGFPGAPGAK 374

Query: 322 TQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGAS--EPSEEVNKASGPRACPPSHHTKL 379
            + G   +  P   G  GP G+       G +GAS    ++ +  A G    P       
Sbjct: 375 GEAGPTGARGPE--GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG------ 426

Query: 380 KKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTA 439
                   +  F  PRG P   +     L    + G P + G  G   PK  P P     
Sbjct: 427 -----IAGAPGFPGPRG-PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP---AG 477

Query: 440 EQGAGG 445
            QGA G
Sbjct: 478 PQGAPG 483



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 74/272 (27%), Positives = 89/272 (32%), Gaps = 38/272 (13%)

Query: 219 EPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGA-GRQQNPCPLFL-GQPDTV-- 274
           +P    EPGL G    G   R G+A         G  G  GR   P P    GQP  +  
Sbjct: 547 DPGRPGEPGLPGAR--GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 275 PWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTK 334
           P        PG     G   A PG   L  + G       P P  P  +RG   +  P+ 
Sbjct: 605 PGPKGANGEPGKAGEKGLPGA-PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 663

Query: 335 GGGL-GPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFEC 393
             GL GP G   EG + G  G   P E    A  P    P           +  ++  + 
Sbjct: 664 FQGLPGPPGPPGEGGKPGDQGV--PGE----AGAPGLVGPRGERGFPGERGSPGAQGLQG 717

Query: 394 PRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTS 453
           PRG P                G+P   G  G+  P  PP        QG  G  E     
Sbjct: 718 PRGLP----------------GTPGTDGPKGASGPAGPPGAQGPPGLQGMPG--ERGAAG 759

Query: 454 IGNKDVDSGQHDEQKGPQ-----DGQASLQDP 480
           I     D G   E KGP+     DG   L  P
Sbjct: 760 IAGPKGDRGDVGE-KGPEGAPGKDGGRGLTGP 790



 Score = 30.8 bits (68), Expect = 8.0
 Identities = 44/171 (25%), Positives = 59/171 (34%), Gaps = 33/171 (19%)

Query: 285 GLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCG-- 342
           GL   +G       +G  G ++GPP             +RG   + PP   G  GP G  
Sbjct: 786 GLTGPIGPPGPAGANGEKG-EVGPPGPAGSAGARGAPGERG--ETGPPGPAGFAGPPGAD 842

Query: 343 -----KCQEGLEGGASGASEPSEEVNKASGPRACP-PSHHTKLKKTWLTRHSEQFECPRG 396
                K ++G  G    A  P  +     GP   P P   T +              P+G
Sbjct: 843 GQPGAKGEQGEAGQKGDAGAPGPQ-----GPSGAPGPQGPTGVTG------------PKG 885

Query: 397 CPEVEERPVAR--LRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGG 445
               +  P A     A  R G P   G+ G+P P  PP P      +GA G
Sbjct: 886 ARGAQGPPGATGFPGAAGRVGPP---GSNGNPGPPGPPGPSGKDGPKGARG 933


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 40.4 bits (93), Expect = 0.010
 Identities = 68/241 (28%), Positives = 81/241 (33%), Gaps = 36/241 (14%)

Query: 225 EPGLFGLNSGGHLQRAGEAERPSLHQRDGEMG----AGRQQNPCPL----FLGQPDTVPW 276
           EPG  G++  G +   G    P     DGE G    AG +  P P     F G P  +P 
Sbjct: 160 EPGEPGVS--GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPG-LPG 216

Query: 277 TSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGG 336
                  PGL    G   A    G    + G P     P P  P   RG      P + G
Sbjct: 217 VKGHRGYPGLDGAKGEAGAPGVKG----ESGSPGENGSPGPMGP---RGL-----PGERG 264

Query: 337 GLGPCGKCQEGLEGGASGASEPSEEVNKASGPR-ACPPSHHTKLKKTWLTRHSEQFECPR 395
             GP G        G  G + P   V  A GP     P    +   T   R  E  + PR
Sbjct: 265 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG-ARGPEGAQGPR 323

Query: 396 GCPEVEERPVARLR-----------ALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAG 444
           G P     P                A   AG+P + GA G P P+ PP P   T   G  
Sbjct: 324 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383

Query: 445 G 445
           G
Sbjct: 384 G 384



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 62/246 (25%), Positives = 80/246 (32%), Gaps = 37/246 (15%)

Query: 202 GSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQ 261
           G++GF    P  P L         PGL G          GEA  P +    G  G    +
Sbjct: 204 GARGF----PGTPGLPGVKGHRGYPGLDGAK--------GEAGAPGVKGESGSPG----E 247

Query: 262 NPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPV 321
           N  P  +G P  +P       P G     GN    PG       +GP   P  P      
Sbjct: 248 NGSPGPMG-PRGLPGERGRTGPAGAAGARGND-GQPGPAGPPGPVGPAGGPGFPGAPGAK 305

Query: 322 TQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGAS--EPSEEVNKASGPRACPPSHHTKL 379
            + G   +  P   G  GP G+       G +GAS    ++ +  A G    P       
Sbjct: 306 GEAGPTGARGPE--GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG------ 357

Query: 380 KKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTA 439
                   +  F  PRG P   +     L    + G P + G  G   PK  P P     
Sbjct: 358 -----IAGAPGFPGPRG-PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP---AG 408

Query: 440 EQGAGG 445
            QGA G
Sbjct: 409 PQGAPG 414



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 74/272 (27%), Positives = 89/272 (32%), Gaps = 38/272 (13%)

Query: 219 EPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGA-GRQQNPCPLFL-GQPDTV-- 274
           +P    EPGL G    G   R G+A         G  G  GR   P P    GQP  +  
Sbjct: 478 DPGRPGEPGLPGAR--GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 535

Query: 275 PWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTK 334
           P        PG     G   A PG   L  + G       P P  P  +RG   +  P+ 
Sbjct: 536 PGPKGANGEPGKAGEKGLPGA-PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 594

Query: 335 GGGL-GPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFEC 393
             GL GP G   EG + G  G   P E    A  P    P           +  ++  + 
Sbjct: 595 FQGLPGPPGPPGEGGKPGDQGV--PGE----AGAPGLVGPRGERGFPGERGSPGAQGLQG 648

Query: 394 PRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTS 453
           PRG P                G+P   G  G+  P  PP        QG  G  E     
Sbjct: 649 PRGLP----------------GTPGTDGPKGASGPAGPPGAQGPPGLQGMPG--ERGAAG 690

Query: 454 IGNKDVDSGQHDEQKGPQ-----DGQASLQDP 480
           I     D G   E KGP+     DG   L  P
Sbjct: 691 IAGPKGDRGDVGE-KGPEGAPGKDGGRGLTGP 721



 Score = 30.8 bits (68), Expect = 8.0
 Identities = 44/171 (25%), Positives = 59/171 (34%), Gaps = 33/171 (19%)

Query: 285 GLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCG-- 342
           GL   +G       +G  G ++GPP             +RG   + PP   G  GP G  
Sbjct: 717 GLTGPIGPPGPAGANGEKG-EVGPPGPAGSAGARGAPGERG--ETGPPGPAGFAGPPGAD 773

Query: 343 -----KCQEGLEGGASGASEPSEEVNKASGPRACP-PSHHTKLKKTWLTRHSEQFECPRG 396
                K ++G  G    A  P  +     GP   P P   T +              P+G
Sbjct: 774 GQPGAKGEQGEAGQKGDAGAPGPQ-----GPSGAPGPQGPTGVTG------------PKG 816

Query: 397 CPEVEERPVAR--LRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGG 445
               +  P A     A  R G P   G+ G+P P  PP P      +GA G
Sbjct: 817 ARGAQGPPGATGFPGAAGRVGPP---GSNGNPGPPGPPGPSGKDGPKGARG 864


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 40.4 bits (93), Expect = 0.010
 Identities = 117/439 (26%), Positives = 148/439 (33%), Gaps = 89/439 (20%)

Query: 28   PGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSWLPPGFPQGPK-----DMLPLVEGEGPQ 82
            PG P  DG    P   G P    +G    P    P G+P GP+     D +  ++G   +
Sbjct: 753  PGMPGADGPPGHPGKEGPPGE--KGGQGPPGPQGPIGYP-GPRGVKGADGIRGLKGTKGE 809

Query: 83   NGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCGPLMPEHSGGHLKSDPVAFRPWH 142
             GE          G++     +  P    GP      GP  P+  GG    DP    P  
Sbjct: 810  KGEDGFPGFKGDMGIKGDRGEIGPP----GPRGED--GPEGPKGRGGP-NGDPGPLGPPG 862

Query: 143  CPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWPLTPHPWVYSGGQPKVPSAFSLG 202
                      E+    VP  LP Y      P+    +P  P      GG+         G
Sbjct: 863  ----------EKGKLGVPG-LPGY-PGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG 910

Query: 203  SKGFYYKDPSIPRLAKEPLA-AAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQ 261
             +G     P+ PR  + P     +PG  G NSGG     G A  P      GE G    Q
Sbjct: 911  QRG-----PTGPRGERGPRGITGKPGPKG-NSGGD----GPAGPP------GERGPNGPQ 954

Query: 262  NPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGD-GNLGYQ--LGPPATPRCPSPE 318
             P           P    P  PPG     G+    PG  G  G+Q   GPP  P    P+
Sbjct: 955  GPTGF--------PGPKGPPGPPGKDGLPGH----PGQRGETGFQGKTGPPGPPGVVGPQ 1002

Query: 319  PPVTQRGCCSSY-------PPTKGGGLGPCGKCQEGLEGGASGASEPSEE----VNKASG 367
             P  + G            PP + G  G  GK  EG +G    A  P ++    +    G
Sbjct: 1003 GPTGETGPMGERGHPGPPGPPGEQGLPGLAGK--EGTKGDPGPAGLPGKDGPPGLRGFPG 1060

Query: 368  PRACP-PSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSP 426
             R  P P     LK           E P G P     P  R      AG+    G  G P
Sbjct: 1061 DRGLPGPVGALGLKGN---------EGPPGPPGPAGSPGER----GPAGAAGPIGIPGRP 1107

Query: 427  APKRPPDPFPGTAEQGAGG 445
             P+ PP P     E+GA G
Sbjct: 1108 GPQGPPGP---AGEKGAPG 1123



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 77/278 (27%), Positives = 97/278 (34%), Gaps = 52/278 (18%)

Query: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGD- 299
            G   +P     DGE G   QQ    LF  + D  P   +P  PPG V   G +   PG+ 
Sbjct: 1186 GPIGQPGPSGADGEPGPRGQQG---LFGQKGDEGP-RGFPG-PPGPVGLQG-LPGPPGEK 1239

Query: 300  ---GNLGYQLGPPATP--RCPSPEP----------------PVTQRG----CCSSYPPTK 334
               G++G Q+GPP  P  R PS  P                 V ++G          P +
Sbjct: 1240 GETGDVG-QMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298

Query: 335  GGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECP 394
            GG  GP G+  E  E G SGA+ P        GP+  P     K      +     F   
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGP-------PGPKGPPGDDGPK-----GSPGPVGFPGD 1346

Query: 395  RGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGG--WQEVRDT 452
             G P  E  P  +       G     G  GSP P   P P     ++G  G    E R  
Sbjct: 1347 PG-PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405

Query: 453  SIGNKDVDSGQHDEQK----GPQDGQASLQDPGLQDIP 486
              G K     +    K    GPQ         GL+ IP
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIP 1443


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 39.7 bits (91), Expect = 0.017
 Identities = 94/352 (26%), Positives = 119/352 (33%), Gaps = 78/352 (22%)

Query: 107 PLAFCGPACPPRCGPLMPEHS----GGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTC 162
           PL  C  A  P   PL P ++     G     PV+    H P +L    L  AP      
Sbjct: 259 PLFHCSDALTPP--PLPPSNNLPAHPGPASQPPVSSATMHLPLVLGP--LGGAPTVEGPG 314

Query: 163 LPPYLVSGL-----PPEHPCDWPLTPHPWVYSGGQPKV--PSAFSLGSKGFYYKDPSIPR 215
            PP+L S L       +HP   PL P P    G +P+   PSA    S     + P  P 
Sbjct: 315 APPFLASSLLSAAAKAQHP---PLPP-PSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP- 369

Query: 216 LAKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVP 275
                     P +F L  G    R  +  R S           R + P P+   QP ++P
Sbjct: 370 ----------PTVFRLLEG----RGPQTPRRS-----------RPRAPAPV--PQPFSLP 402

Query: 276 WTSWPACPPGLVHTLGNVWAGPG--DGN---LGYQLGPPATPRCPSPEPPVTQRGCCSSY 330
             S P  P  ++  LG    GP   DG+   LG     P  P   S  PP  +     S 
Sbjct: 403 EPSQPILP-SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSL 461

Query: 331 PPTKGGGLGPCGKCQEGLEGGASGA------SEPSEEVNKASGPRACPPSHHTKLKKTWL 384
           P T  G L              +          PSE +   +GP ACP            
Sbjct: 462 PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGP-ACPLPP--------- 511

Query: 385 TRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFP 436
               E F  P   PE       +  AL  AG P + GA+  P     P P P
Sbjct: 512 LAGGEAFPFPS--PE-------QGLALSGAGFPGMLGALPLPLSLGQPPPSP 554



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 119/476 (25%), Positives = 150/476 (31%), Gaps = 100/476 (21%)

Query: 8   LKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAP------FWRGVLS------ 55
           L G   +   +PE G+     G P   G    PL LG+P P         GVL+      
Sbjct: 512 LAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQP 571

Query: 56  TPDSWLPPGFPQGPKDMLPLVEGEGPQ-----------------NGERKVNWLGSKEGLR 98
            P+  LPP  P GP   L   E EGP                        N L S     
Sbjct: 572 PPEPLLPP--PGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLAS----- 624

Query: 99  WKEAMLTHPLAFCGPACPPRCGPLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFW 158
           +   +   P A  G       G    E   G     P+ F P   P    T I   +   
Sbjct: 625 FLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAP---PTLIALNSALL 681

Query: 159 VPTCLPPYLVSGLPPEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAK 218
             T  PP   SG PP+          P V S  QP  P++    S      DP    L K
Sbjct: 682 AATLDPP---SGTPPQ----------PCVLSAPQPGPPTS----SVTTATTDPGASSLGK 724

Query: 219 EPLAAAEP-----GLFGLNSGGHLQ--RAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQP 271
            P  +  P      L G +  G L    +     PSL Q  G + +G+         G P
Sbjct: 725 APSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAP 784

Query: 272 DTVPWTSWP-AC-------PPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCP---SPEPP 320
             +   S P AC       PP            P          PP +   P   SP+PP
Sbjct: 785 PPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPP 844

Query: 321 VTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLK 380
           V +           G G G  G+   G   G +G + P+    +  G R  P     +L 
Sbjct: 845 VPEL--------LTGRGSGKRGRRGGGGLRGINGEARPAR--GRKPGSRREP----GRLA 890

Query: 381 KTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFP 436
             W TR         G     ER   R    +  G    + A G   PK PP P P
Sbjct: 891 LKWGTR--------GGFNGQMERSPRRTHHWQHNG----ELAEGGAEPKDPPPPGP 934


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 39.3 bits (90), Expect = 0.023
 Identities = 65/247 (26%), Positives = 74/247 (29%), Gaps = 51/247 (20%)

Query: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 300
            G    P +   DGE G   QQ       GQ        +P  PPG +   G +   PG+ 
Sbjct: 1168 GPVGAPGIAGGDGEPGPRGQQG----MFGQKGDEGARGFPG-PPGPIGLQG-LPGPPGEK 1221

Query: 301  NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 360
                 +GP   P  P P  P    G          G  GP G    G  GG     EP E
Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQGPNGA--------DGPQGPPGSV--GSVGGVGEKGEPGE 1271

Query: 361  EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 420
              N        PP                  E   G P+ E            AG P  +
Sbjct: 1272 AGNPG------PPG-----------------EAGVGGPKGERGEKGEAGPPGAAGPPGAK 1308

Query: 421  GAMGSPAPKRPPDP--FPG----TAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQ 474
            G  G   PK  P P  FPG      E G  G   V       +D D G    Q GP    
Sbjct: 1309 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK--GEDGDPG----QPGPPGPS 1362

Query: 475  ASLQDPG 481
                 PG
Sbjct: 1363 GEAGPPG 1369



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 54/190 (28%), Positives = 67/190 (35%), Gaps = 37/190 (19%)

Query: 271  PDTVPWTSWPACPPGLVHTLGNVWAGPGD-GNLGYQ--LGPPATPRCPSPEPPVTQRGCC 327
            P   P    P  PPG     G+    PG  G  G+Q   GPP       P+ P  + G  
Sbjct: 938  PVGFPGPKGPPGPPGKDGLPGH----PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 993

Query: 328  SSY-------PPTKGGGLGPCGKCQEGLEG-----GASGASEPSEEVNKASGPRACPPSH 375
                      PP + G  G  GK  EG +G     G SG   P+  +    G R  P + 
Sbjct: 994  GERGHPGPPGPPGEQGLPGAAGK--EGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQ 1050

Query: 376  HTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPF 435
                 K          E P+G P     PV        AG+    G  G P P+ PP P 
Sbjct: 1051 GAPGLKGG--------EGPQGPPG----PVGSPGERGSAGTAGPIGLPGRPGPQGPPGP- 1097

Query: 436  PGTAEQGAGG 445
                E+GA G
Sbjct: 1098 --AGEKGAPG 1105


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 39.3 bits (90), Expect = 0.023
 Identities = 65/247 (26%), Positives = 74/247 (29%), Gaps = 51/247 (20%)

Query: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 300
            G    P +   DGE G   QQ       GQ        +P  PPG +   G +   PG+ 
Sbjct: 1117 GPVGAPGIAGGDGEPGPRGQQG----MFGQKGDEGARGFPG-PPGPIGLQG-LPGPPGEK 1170

Query: 301  NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 360
                 +GP   P  P P  P    G          G  GP G    G  GG     EP E
Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQGPNGA--------DGPQGPPGSV--GSVGGVGEKGEPGE 1220

Query: 361  EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 420
              N        PP                  E   G P+ E            AG P  +
Sbjct: 1221 AGNPG------PPG-----------------EAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257

Query: 421  GAMGSPAPKRPPDP--FPG----TAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQ 474
            G  G   PK  P P  FPG      E G  G   V       +D D G    Q GP    
Sbjct: 1258 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK--GEDGDPG----QPGPPGPS 1311

Query: 475  ASLQDPG 481
                 PG
Sbjct: 1312 GEAGPPG 1318



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 54/190 (28%), Positives = 67/190 (35%), Gaps = 37/190 (19%)

Query: 271  PDTVPWTSWPACPPGLVHTLGNVWAGPGD-GNLGYQ--LGPPATPRCPSPEPPVTQRGCC 327
            P   P    P  PPG     G+    PG  G  G+Q   GPP       P+ P  + G  
Sbjct: 887  PVGFPGPKGPPGPPGKDGLPGH----PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 942

Query: 328  SSY-------PPTKGGGLGPCGKCQEGLEG-----GASGASEPSEEVNKASGPRACPPSH 375
                      PP + G  G  GK  EG +G     G SG   P+  +    G R  P + 
Sbjct: 943  GERGHPGPPGPPGEQGLPGAAGK--EGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQ 999

Query: 376  HTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPF 435
                 K          E P+G P     PV        AG+    G  G P P+ PP P 
Sbjct: 1000 GAPGLKGG--------EGPQGPPG----PVGSPGERGSAGTAGPIGLPGRPGPQGPPGP- 1046

Query: 436  PGTAEQGAGG 445
                E+GA G
Sbjct: 1047 --AGEKGAPG 1054


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 39.3 bits (90), Expect = 0.023
 Identities = 65/247 (26%), Positives = 74/247 (29%), Gaps = 51/247 (20%)

Query: 241  GEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDG 300
            G    P +   DGE G   QQ       GQ        +P  PPG +   G +   PG+ 
Sbjct: 1156 GPVGAPGIAGGDGEPGPRGQQG----MFGQKGDEGARGFPG-PPGPIGLQG-LPGPPGEK 1209

Query: 301  NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSE 360
                 +GP   P  P P  P    G          G  GP G    G  GG     EP E
Sbjct: 1210 GENGDVGPMGPPGPPGPRGPQGPNGA--------DGPQGPPGSV--GSVGGVGEKGEPGE 1259

Query: 361  EVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ 420
              N        PP                  E   G P+ E            AG P  +
Sbjct: 1260 AGNPG------PPG-----------------EAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296

Query: 421  GAMGSPAPKRPPDP--FPG----TAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQ 474
            G  G   PK  P P  FPG      E G  G   V       +D D G    Q GP    
Sbjct: 1297 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK--GEDGDPG----QPGPPGPS 1350

Query: 475  ASLQDPG 481
                 PG
Sbjct: 1351 GEAGPPG 1357



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 54/190 (28%), Positives = 67/190 (35%), Gaps = 37/190 (19%)

Query: 271  PDTVPWTSWPACPPGLVHTLGNVWAGPGD-GNLGYQ--LGPPATPRCPSPEPPVTQRGCC 327
            P   P    P  PPG     G+    PG  G  G+Q   GPP       P+ P  + G  
Sbjct: 926  PVGFPGPKGPPGPPGKDGLPGH----PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 981

Query: 328  SSY-------PPTKGGGLGPCGKCQEGLEG-----GASGASEPSEEVNKASGPRACPPSH 375
                      PP + G  G  GK  EG +G     G SG   P+  +    G R  P + 
Sbjct: 982  GERGHPGPPGPPGEQGLPGAAGK--EGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQ 1038

Query: 376  HTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPF 435
                 K          E P+G P     PV        AG+    G  G P P+ PP P 
Sbjct: 1039 GAPGLKGG--------EGPQGPPG----PVGSPGERGSAGTAGPIGLPGRPGPQGPPGP- 1085

Query: 436  PGTAEQGAGG 445
                E+GA G
Sbjct: 1086 --AGEKGAPG 1093


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 39.3 bits (90), Expect = 0.023
 Identities = 82/353 (23%), Positives = 104/353 (29%), Gaps = 100/353 (28%)

Query: 225 EPGLFGLNSGGHLQRAGEAERPS-LHQRDGEMGAGR-----------------------Q 260
           EPG     SGG    AG ++ P  L    G MGAG+                        
Sbjct: 538 EPG----GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPN 593

Query: 261 QNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPP 320
            +P    L QPD          P GL+        GPG    G+  G P  P+       
Sbjct: 594 SHPSEELLKQPDYSDKIKQMLVPHGLL--------GPGPIANGFPPGGPGGPKG------ 639

Query: 321 VTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLK 380
                    +PP  GG +        G  GG  G   P     +  GP   PP       
Sbjct: 640 ------MQHFPPGPGGPM-------PGPHGGPGGPVGP-----RLLGP---PPP------ 672

Query: 381 KTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSP--------EVQGAMGSPAPKRPP 432
                        PRG     + P   +R     G P          +G  G   P  PP
Sbjct: 673 -------------PRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPP 719

Query: 433 DPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDPGLQDIPCLALPA 492
            PF G     +GG         G   V  G H   +GP  G  +       + P   + +
Sbjct: 720 PPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS 779

Query: 493 KLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEGPGSG 545
                +    + G GGGH  H       P GG         +     EGPG G
Sbjct: 780 GHRPHEGPGGSMGGGGGHRPH-----EGPGGG-----ISGGSGHRPHEGPGGG 822


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,015,661
Number of Sequences: 37866
Number of extensions: 4025113
Number of successful extensions: 17749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 351
Number of HSP's that attempted gapping in prelim test: 15901
Number of HSP's gapped (non-prelim): 2253
length of query: 1189
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1076
effective length of database: 13,968,660
effective search space: 15030278160
effective search space used: 15030278160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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