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Search of human proteins with 115430245
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115430245 arylhydrocarbon receptor repressor [Homo sapiens]
(719 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115430245 arylhydrocarbon receptor repressor [Homo sapiens] 1490 0.0
gi|4502003 aryl hydrocarbon receptor [Homo sapiens] 298 9e-81
gi|22027482 neuronal PAS domain protein 1 [Homo sapiens] 92 2e-18
gi|4827004 single-minded homolog 2 long isoform [Homo sapiens] 91 5e-18
gi|194239684 single-minded homolog 2 short isoform [Homo sapiens] 91 5e-18
gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens] 83 8e-16
gi|21614542 single-minded homolog 1 [Homo sapiens] 79 1e-14
gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens] 79 1e-14
gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens] 73 1e-12
gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens] 73 1e-12
gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens] 73 1e-12
gi|23065535 hypoxia inducible factor 3, alpha subunit isoform a ... 71 3e-12
gi|90421311 hypoxia inducible factor 3, alpha subunit isoform c ... 71 3e-12
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ... 69 2e-11
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ... 69 2e-11
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ... 69 2e-11
gi|5729858 nuclear receptor coactivator 2 [Homo sapiens] 68 3e-11
gi|31077211 hypoxia-inducible factor 1, alpha subunit isoform 2 ... 67 8e-11
gi|4504385 hypoxia-inducible factor 1, alpha subunit isoform 1 [... 67 8e-11
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 66 1e-10
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 66 1e-10
gi|40254439 endothelial PAS domain protein 1 [Homo sapiens] 62 1e-09
gi|30795242 aryl hydrocarbon receptor nuclear translocator isofo... 62 2e-09
gi|30795240 aryl hydrocarbon receptor nuclear translocator isofo... 62 2e-09
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor... 62 2e-09
gi|194097477 neuronal PAS domain protein 4 [Homo sapiens] 59 1e-08
gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Ho... 57 5e-08
gi|31745180 aryl hydrocarbon receptor nuclear translocator-like ... 57 6e-08
gi|22027471 neuronal PAS domain protein 2 [Homo sapiens] 57 8e-08
gi|4758010 clock [Homo sapiens] 53 1e-06
>gi|115430245 arylhydrocarbon receptor repressor [Homo sapiens]
Length = 719
Score = 1490 bits (3858), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPD 60
MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPD
Sbjct: 1 MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPD 60
Query: 61 IISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLL 120
IISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLL
Sbjct: 61 IISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLL 120
Query: 121 ESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMD 180
ESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMD
Sbjct: 121 ESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMD 180
Query: 181 PPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFL 240
PPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFL
Sbjct: 181 PPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFL 240
Query: 241 ARGSQAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSA 300
ARGSQAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSA
Sbjct: 241 ARGSQAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSA 300
Query: 301 AEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQ 360
AEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQ
Sbjct: 301 AEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQ 360
Query: 361 TDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTK 420
TDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTK
Sbjct: 361 TDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTK 420
Query: 421 PLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPS 480
PLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPS
Sbjct: 421 PLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPS 480
Query: 481 AYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMP 540
AYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMP
Sbjct: 481 AYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMP 540
Query: 541 PGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDS 600
PGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDS
Sbjct: 541 PGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDS 600
Query: 601 RQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARG 660
RQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARG
Sbjct: 601 RQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARG 660
Query: 661 RGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP 719
RGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP
Sbjct: 661 RGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP 719
>gi|4502003 aryl hydrocarbon receptor [Homo sapiens]
Length = 848
Score = 298 bits (764), Expect = 9e-81
Identities = 186/413 (45%), Positives = 238/413 (57%), Gaps = 51/413 (12%)
Query: 12 TYAGRKRRRPLQKQRPAVGAE--KSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLS 69
TYA RKRR+P+QK + AE KSNPSKRHRDRLN ELD LASLLPFP D+I+KLDKLS
Sbjct: 9 TYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLS 68
Query: 70 VLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLA----GSAVLEGRLLLESLNG 125
VLRLSVSYLR KSFF V + S + G D+C A G + EG LL++LNG
Sbjct: 69 VLRLSVSYLRAKSFFDVALKSSPTERNGGQ----DNCRAANFREGLNLQEGEFLLQALNG 124
Query: 126 FALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVV 185
F LVV+ + +FYAS+TI DYLGF Q+DV+HQ++Y+ IH +DR +F RQLHWA++P Q
Sbjct: 125 FVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCT 184
Query: 186 -FGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFLARGS 244
GQ TG + Q P E S + RCFICR+RCLLD++SGFLA
Sbjct: 185 ESGQGIEEATGLPQTVVCYNPDQ-----IPPENSPLMERCFICRLRCLLDNSSGFLA--- 236
Query: 245 QAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMK 304
M FQGKLK+L GQKKK G++LPP+L+LF IA P+ PS E++
Sbjct: 237 ---------------MNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIR 281
Query: 305 MRSALLRAKPRAD-TAATADAKVKATTSLCESELHGKPN-----------YSAGRSSR-- 350
++ + R K + D T DAK + E+EL + + Y A R
Sbjct: 282 TKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMI 341
Query: 351 ---ESGVLVLREQTDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQH 400
ESG++V R T RW V + A L G PD ++ + D E +H
Sbjct: 342 KTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEH 394
>gi|22027482 neuronal PAS domain protein 1 [Homo sapiens]
Length = 590
Score = 91.7 bits (226), Expect = 2e-18
Identities = 69/200 (34%), Positives = 96/200 (48%), Gaps = 27/200 (13%)
Query: 1 MPRTMI--PPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFP 58
+P M+ P G C A RK + N ++ R + N E LA LLP P
Sbjct: 29 LPGLMVKAPSGPCLQAQRKEK-------------SRNAARSRRGKENLEFFELAKLLPLP 75
Query: 59 PDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPS---PGDSCPLA-GSAVL 114
I S+LDK S++RLSV+YLR++ F + + AAG P+ PG P A S V
Sbjct: 76 GAISSQLDKASIVRLSVTYLRLRRFAALGAPPWGLR-AAGPPAGLAPGRRGPAALVSEVF 134
Query: 115 EGRL---LLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDF 171
E L +L+SL+GF ++ EG Y S T+ YLG Q ++ +++DYIH D +
Sbjct: 135 EQHLGGHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVEMTGSSVFDYIHPGDHSEV 194
Query: 172 CRQLHWAMDPPQVVFGQPPP 191
QL P G P P
Sbjct: 195 LEQLGLRTPTP----GPPTP 210
>gi|4827004 single-minded homolog 2 long isoform [Homo sapiens]
Length = 667
Score = 90.5 bits (223), Expect = 5e-18
Identities = 54/140 (38%), Positives = 79/140 (56%), Gaps = 8/140 (5%)
Query: 32 EKS-NPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
EKS N +K R++ N E LA LLP P I S+LDK S++RL+ SYL++++ F
Sbjct: 3 EKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGD 62
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
+ QP+ PL G A G LL++L+GF VV+++G I Y S T +LG
Sbjct: 63 AWGQPSRAG-------PLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLS 115
Query: 151 QTDVMHQNIYDYIHVDDRQD 170
Q ++ +IY+YIH D +
Sbjct: 116 QVELTGNSIYEYIHPSDHDE 135
>gi|194239684 single-minded homolog 2 short isoform [Homo sapiens]
Length = 570
Score = 90.5 bits (223), Expect = 5e-18
Identities = 54/140 (38%), Positives = 79/140 (56%), Gaps = 8/140 (5%)
Query: 32 EKS-NPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
EKS N +K R++ N E LA LLP P I S+LDK S++RL+ SYL++++ F
Sbjct: 3 EKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGD 62
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
+ QP+ PL G A G LL++L+GF VV+++G I Y S T +LG
Sbjct: 63 AWGQPSRAG-------PLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLS 115
Query: 151 QTDVMHQNIYDYIHVDDRQD 170
Q ++ +IY+YIH D +
Sbjct: 116 QVELTGNSIYEYIHPSDHDE 135
>gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens]
Length = 901
Score = 83.2 bits (204), Expect = 8e-16
Identities = 58/182 (31%), Positives = 88/182 (48%), Gaps = 16/182 (8%)
Query: 21 PLQKQR-PAVGAEKSNPSKR-HRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYL 78
P +++R A+ EKS + R R + N E LA LLP P I S+LDK S++RL++SYL
Sbjct: 12 PSRRERLQALRKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTISYL 71
Query: 79 RVKSFFQVVQEQSSRQPAAGAPSPGDSCPLA---------GSAVLEGRL---LLESLNGF 126
+++ F Q P P S A V E L +L+SL+GF
Sbjct: 72 KMRDFAN--QGDPPWNLRMEGPPPNTSVKGAQRRRSPSALAIEVFEAHLGSHILQSLDGF 129
Query: 127 ALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVF 186
++ EG Y S T+ YLG Q ++ +++DY+H D + QL + P + +
Sbjct: 130 VFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHPGDHVEMAEQLGMKLPPGRGLL 189
Query: 187 GQ 188
Q
Sbjct: 190 SQ 191
>gi|21614542 single-minded homolog 1 [Homo sapiens]
Length = 766
Score = 79.0 bits (193), Expect = 1e-14
Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Query: 32 EKS-NPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
EKS N ++ R++ N+E LA LLP P I S+LDK S++RL+ SYL+++ F
Sbjct: 3 EKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVF-----P 57
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
A G S + PL G LL++L+GF VV+ +G I Y S T +LG
Sbjct: 58 EGLGEAWGHSS--RTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLS 115
Query: 151 QTDVMHQNIYDYIHVDDRQD 170
Q ++ +IY+YIH D +
Sbjct: 116 QVELTGNSIYEYIHPADHDE 135
>gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]
Length = 920
Score = 79.0 bits (193), Expect = 1e-14
Identities = 59/201 (29%), Positives = 91/201 (45%), Gaps = 35/201 (17%)
Query: 21 PLQKQR-PAVGAEKSNPSKR-HRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYL 78
P +++R A+ EKS + R R + N E LA LLP P I S+LDK S++RL++SYL
Sbjct: 12 PSRRERLQALRKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTISYL 71
Query: 79 RVKSFFQVVQEQSSRQPAAGAPSPGDS-----------------CPLAGSA--------- 112
+++ F Q P P S C + G+
Sbjct: 72 KMRDFAN--QGDPPWNLRMEGPPPNTSVKGIQMWKSELCMRKTPCEVIGAQRRRSPSALA 129
Query: 113 --VLEGRL---LLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDD 167
V E L +L+SL+GF ++ EG Y S T+ YLG Q ++ +++DY+H D
Sbjct: 130 IEVFEAHLGSHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHPGD 189
Query: 168 RQDFCRQLHWAMDPPQVVFGQ 188
+ QL + P + + Q
Sbjct: 190 HVEMAEQLGMKLPPGRGLLSQ 210
>gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens]
Length = 1399
Score = 72.8 bits (177), Expect = 1e-12
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 10/164 (6%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKL----DKLSVLRLSVSYLRVKSFFQVVQE 89
S+ KR R++ N L+ LA LL I L DK +L+ +V +++ ++ QE
Sbjct: 29 SSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMK--RMEQE 86
Query: 90 QSSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGF 149
+S+ S G LLLE+L+GF VV+ EG I + S + YLG+
Sbjct: 87 KSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGY 146
Query: 150 HQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLE 193
+Q ++M+ ++Y +HV D +F + L P +V G P P E
Sbjct: 147 NQEELMNTSVYSILHVGDHAEFVKNLL----PKSLVNGVPWPQE 186
>gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens]
Length = 1440
Score = 72.8 bits (177), Expect = 1e-12
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 10/164 (6%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKL----DKLSVLRLSVSYLRVKSFFQVVQE 89
S+ KR R++ N L+ LA LL I L DK +L+ +V +++ ++ QE
Sbjct: 29 SSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMK--RMEQE 86
Query: 90 QSSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGF 149
+S+ S G LLLE+L+GF VV+ EG I + S + YLG+
Sbjct: 87 KSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGY 146
Query: 150 HQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLE 193
+Q ++M+ ++Y +HV D +F + L P +V G P P E
Sbjct: 147 NQEELMNTSVYSILHVGDHAEFVKNLL----PKSLVNGVPWPQE 186
>gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens]
Length = 1441
Score = 72.8 bits (177), Expect = 1e-12
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 10/164 (6%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKL----DKLSVLRLSVSYLRVKSFFQVVQE 89
S+ KR R++ N L+ LA LL I L DK +L+ +V +++ ++ QE
Sbjct: 29 SSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMK--RMEQE 86
Query: 90 QSSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGF 149
+S+ S G LLLE+L+GF VV+ EG I + S + YLG+
Sbjct: 87 KSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGY 146
Query: 150 HQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLE 193
+Q ++M+ ++Y +HV D +F + L P +V G P P E
Sbjct: 147 NQEELMNTSVYSILHVGDHAEFVKNLL----PKSLVNGVPWPQE 186
>gi|23065535 hypoxia inducible factor 3, alpha subunit isoform a
[Homo sapiens]
Length = 667
Score = 71.2 bits (173), Expect = 3e-12
Identities = 105/465 (22%), Positives = 169/465 (36%), Gaps = 107/465 (23%)
Query: 32 EKSNPSKRHRDRLNAE-LDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
EKS + R R E L LA LPF + + LDK S++RL++SYLR+ ++
Sbjct: 15 EKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMH---RLCAAG 71
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
Q AG P D+C L++L GF +V++AEG + Y S + +LG
Sbjct: 72 EWNQVGAGG-EPLDAC------------YLKALEGFVMVLTAEGDMAYLSENVSKHLGLS 118
Query: 151 QTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWG 210
Q +++ +I+D+IH D++ +L A+ P Q + +
Sbjct: 119 QLELIGHSIFDFIHPCDQE----ELQDALTPQQTLSRRK--------------------- 153
Query: 211 TGTPTEYSAFLTRCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTMQFQGKLKFLF 270
PTE RCF R++ L S L + W++ C G ++
Sbjct: 154 VEAPTE------RCFSLRMKSTLTSRGRTLNLKAATWKVLNC----------SGHMRAYK 197
Query: 271 GQKKKAPSGA--MLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAAT-ADAKVK 327
+ +P+G+ PP L I + P + E + ++ D T D ++
Sbjct: 198 PPAQTSPAGSPDSEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDDRIA 257
Query: 328 ATTSLCESELHGKPNY------SAGRSSRESGVLVLREQTDAGRWAQVPARAPCLCLRGG 381
+L G Y + S+ L+ + Q G++ + L +
Sbjct: 258 EVAGYSPDDLIGCSAYEYIHALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQ 317
Query: 382 PDLVLDPKGGSGDREE------------------------EQHRMLSRASGVTGRRETPG 417
+V GG G + E EQH G +++TP
Sbjct: 318 ATVV---SGGRGPQSESIVCVHFLISQVEETGVVLSLEQTEQHSRRPIQRGAPSQKDTPN 374
Query: 418 PTKPLPWTAGKHSEDGARPR----LQPSKNDPPSLRPMPRGSCLP 458
P L D PR L P +L PR C P
Sbjct: 375 PGDSL---------DTPGPRILAFLHPPSLSEAALAADPRRFCSP 410
>gi|90421311 hypoxia inducible factor 3, alpha subunit isoform c
[Homo sapiens]
Length = 669
Score = 71.2 bits (173), Expect = 3e-12
Identities = 105/465 (22%), Positives = 169/465 (36%), Gaps = 107/465 (23%)
Query: 32 EKSNPSKRHRDRLNAE-LDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
EKS + R R E L LA LPF + + LDK S++RL++SYLR+ ++
Sbjct: 17 EKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMH---RLCAAG 73
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
Q AG P D+C L++L GF +V++AEG + Y S + +LG
Sbjct: 74 EWNQVGAGG-EPLDAC------------YLKALEGFVMVLTAEGDMAYLSENVSKHLGLS 120
Query: 151 QTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWG 210
Q +++ +I+D+IH D++ +L A+ P Q + +
Sbjct: 121 QLELIGHSIFDFIHPCDQE----ELQDALTPQQTLSRRK--------------------- 155
Query: 211 TGTPTEYSAFLTRCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTMQFQGKLKFLF 270
PTE RCF R++ L S L + W++ C G ++
Sbjct: 156 VEAPTE------RCFSLRMKSTLTSRGRTLNLKAATWKVLNC----------SGHMRAYK 199
Query: 271 GQKKKAPSGA--MLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAAT-ADAKVK 327
+ +P+G+ PP L I + P + E + ++ D T D ++
Sbjct: 200 PPAQTSPAGSPDSEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDDRIA 259
Query: 328 ATTSLCESELHGKPNY------SAGRSSRESGVLVLREQTDAGRWAQVPARAPCLCLRGG 381
+L G Y + S+ L+ + Q G++ + L +
Sbjct: 260 EVAGYSPDDLIGCSAYEYIHALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQ 319
Query: 382 PDLVLDPKGGSGDREE------------------------EQHRMLSRASGVTGRRETPG 417
+V GG G + E EQH G +++TP
Sbjct: 320 ATVV---SGGRGPQSESIVCVHFLISQVEETGVVLSLEQTEQHSRRPIQRGAPSQKDTPN 376
Query: 418 PTKPLPWTAGKHSEDGARPR----LQPSKNDPPSLRPMPRGSCLP 458
P L D PR L P +L PR C P
Sbjct: 377 PGDSL---------DTPGPRILAFLHPPSLSEAALAADPRRFCSP 412
>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
isoform b [Homo sapiens]
Length = 582
Score = 68.6 bits (166), Expect = 2e-11
Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 30/202 (14%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S KR RD++N+ +D LASL+P + KLDKL+VLR++V +++
Sbjct: 35 SQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKT------------- 81
Query: 94 QPAAGAPSPGDSCPLAGSAVLEG---RLLLESLNGFALVVSAE-GTIFYASATIVDYLGF 149
GA +P + + + L+L + +GF VV + G I + S ++ L +
Sbjct: 82 --LRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNY 139
Query: 150 HQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEW 209
Q D++ Q+++DY+H D A Q+ P E DA G ++
Sbjct: 140 SQNDLIGQSLFDYLHPKD---------IAKVKEQLSSSDTAPRERLIDAKTGLPVKTDI- 189
Query: 210 GTGTPTEYSAFLTRCFICRVRC 231
T P+ + R F CR++C
Sbjct: 190 -TPGPSRLCSGARRSFFCRMKC 210
>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 68.6 bits (166), Expect = 2e-11
Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 30/202 (14%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S KR RD++N+ +D LASL+P + KLDKL+VLR++V +++
Sbjct: 78 SQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKT------------- 124
Query: 94 QPAAGAPSPGDSCPLAGSAVLEG---RLLLESLNGFALVVSAE-GTIFYASATIVDYLGF 149
GA +P + + + L+L + +GF VV + G I + S ++ L +
Sbjct: 125 --LRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNY 182
Query: 150 HQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEW 209
Q D++ Q+++DY+H D A Q+ P E DA G ++
Sbjct: 183 SQNDLIGQSLFDYLHPKD---------IAKVKEQLSSSDTAPRERLIDAKTGLPVKTDI- 232
Query: 210 GTGTPTEYSAFLTRCFICRVRC 231
T P+ + R F CR++C
Sbjct: 233 -TPGPSRLCSGARRSFFCRMKC 253
>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 68.6 bits (166), Expect = 2e-11
Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 30/202 (14%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S KR RD++N+ +D LASL+P + KLDKL+VLR++V +++
Sbjct: 78 SQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKT------------- 124
Query: 94 QPAAGAPSPGDSCPLAGSAVLEG---RLLLESLNGFALVVSAE-GTIFYASATIVDYLGF 149
GA +P + + + L+L + +GF VV + G I + S ++ L +
Sbjct: 125 --LRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNY 182
Query: 150 HQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEW 209
Q D++ Q+++DY+H D A Q+ P E DA G ++
Sbjct: 183 SQNDLIGQSLFDYLHPKD---------IAKVKEQLSSSDTAPRERLIDAKTGLPVKTDI- 232
Query: 210 GTGTPTEYSAFLTRCFICRVRC 231
T P+ + R F CR++C
Sbjct: 233 -TPGPSRLCSGARRSFFCRMKC 253
>gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]
Length = 1464
Score = 68.2 bits (165), Expect = 3e-11
Identities = 49/185 (26%), Positives = 90/185 (48%), Gaps = 26/185 (14%)
Query: 16 RKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPDIIS----KLDKLSVL 71
RKR+ + P+ K N KR+R++ N ++ LA L+ + I K DK ++L
Sbjct: 17 RKRKECPDQLGPS---PKRNTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAIL 73
Query: 72 RLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLE----GRLLLESLNGFA 127
+ +V +R ++EQ A G V++ G ++LE+L+GF
Sbjct: 74 KETVKQIRQ------IKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMMLEALDGFF 127
Query: 128 LVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQL---------HWA 178
VV+ EG + + S + YL ++Q ++M++++Y +HV D +F + L W+
Sbjct: 128 FVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSIVNGGSWS 187
Query: 179 MDPPQ 183
+PP+
Sbjct: 188 GEPPR 192
>gi|31077211 hypoxia-inducible factor 1, alpha subunit isoform 2
[Homo sapiens]
Length = 735
Score = 66.6 bits (161), Expect = 8e-11
Identities = 70/314 (22%), Positives = 117/314 (37%), Gaps = 59/314 (18%)
Query: 32 EKSNPSKRHRDRLNAELDH-LASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
EKS + R R +E+ + LA LP P ++ S LDK SV+RL++SYLRV+
Sbjct: 20 EKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDA---- 75
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
GD L++L+GF +V++ +G + Y S + Y+G
Sbjct: 76 ------------GDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLT 123
Query: 151 QTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWG 210
Q ++ +++D+ H D ++ L G + + +E
Sbjct: 124 QFELTGHSVFDFTHPCDHEEMREMLTHRN---------------------GLVKKGKEQN 162
Query: 211 TGTPTEYSAFLTRCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTMQFQGKLKFLF 270
T R F R++C L S + S W++ C G +
Sbjct: 163 T----------QRSFFLRMKCTLTSRGRTMNIKSATWKVLHC----------TGHIHVYD 202
Query: 271 GQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTA-ATADAKVKAT 329
+ G PP L I P+ PS E+ + S ++ D + D ++
Sbjct: 203 TNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITEL 262
Query: 330 TSLCESELHGKPNY 343
EL G+ Y
Sbjct: 263 MGYEPEELLGRSIY 276
Score = 32.0 bits (71), Expect = 2.1
Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%)
Query: 87 VQEQSSRQPAAGAPSPGDSC------PLAGSAVLEGRLLLESLNGFALVVSAEGTIFYAS 140
V + +S QP G P +C P+ + +E + L+S F S + Y
Sbjct: 200 VYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIE--IPLDSKT-FLSRHSLDMKFSYCD 256
Query: 141 ATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQ 188
I + +G+ +++ ++IY+Y H D + H QV GQ
Sbjct: 257 ERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQ 304
>gi|4504385 hypoxia-inducible factor 1, alpha subunit isoform 1
[Homo sapiens]
Length = 826
Score = 66.6 bits (161), Expect = 8e-11
Identities = 70/314 (22%), Positives = 117/314 (37%), Gaps = 59/314 (18%)
Query: 32 EKSNPSKRHRDRLNAELDH-LASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
EKS + R R +E+ + LA LP P ++ S LDK SV+RL++SYLRV+
Sbjct: 20 EKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDA---- 75
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
GD L++L+GF +V++ +G + Y S + Y+G
Sbjct: 76 ------------GDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLT 123
Query: 151 QTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWG 210
Q ++ +++D+ H D ++ L G + + +E
Sbjct: 124 QFELTGHSVFDFTHPCDHEEMREMLTHRN---------------------GLVKKGKEQN 162
Query: 211 TGTPTEYSAFLTRCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTMQFQGKLKFLF 270
T R F R++C L S + S W++ C G +
Sbjct: 163 T----------QRSFFLRMKCTLTSRGRTMNIKSATWKVLHC----------TGHIHVYD 202
Query: 271 GQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTA-ATADAKVKAT 329
+ G PP L I P+ PS E+ + S ++ D + D ++
Sbjct: 203 TNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITEL 262
Query: 330 TSLCESELHGKPNY 343
EL G+ Y
Sbjct: 263 MGYEPEELLGRSIY 276
Score = 32.0 bits (71), Expect = 2.1
Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%)
Query: 87 VQEQSSRQPAAGAPSPGDSC------PLAGSAVLEGRLLLESLNGFALVVSAEGTIFYAS 140
V + +S QP G P +C P+ + +E + L+S F S + Y
Sbjct: 200 VYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIE--IPLDSKT-FLSRHSLDMKFSYCD 256
Query: 141 ATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQ 188
I + +G+ +++ ++IY+Y H D + H QV GQ
Sbjct: 257 ERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQ 304
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 65.9 bits (159), Expect = 1e-10
Identities = 48/171 (28%), Positives = 85/171 (49%), Gaps = 18/171 (10%)
Query: 14 AGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPDIIS----KLDKLS 69
A R+R L P G S KR R++ + ++ LA L+ I K DK +
Sbjct: 12 ASDSRKRKLPCDTPGQGLTCSG-EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCA 70
Query: 70 VLRLSVSYLR-VKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLE----GRLLLESLN 124
+L+ +V +R +K + + Q A + + G V++ G LLL++L+
Sbjct: 71 ILKETVRQIRQIKEQGKTISNDDDVQKADVSST--------GQGVIDKDSLGPLLLQALD 122
Query: 125 GFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQL 175
GF VV+ +G I + S + YL + Q D+++ ++Y+ +H +DR+DF + L
Sbjct: 123 GFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNL 173
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 65.9 bits (159), Expect = 1e-10
Identities = 48/171 (28%), Positives = 85/171 (49%), Gaps = 18/171 (10%)
Query: 14 AGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPDIIS----KLDKLS 69
A R+R L P G S KR R++ + ++ LA L+ I K DK +
Sbjct: 12 ASDSRKRKLPCDTPGQGLTCSG-EKRRREQESKYIEELAELISANLSDIDNFNVKPDKCA 70
Query: 70 VLRLSVSYLR-VKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLE----GRLLLESLN 124
+L+ +V +R +K + + Q A + + G V++ G LLL++L+
Sbjct: 71 ILKETVRQIRQIKEQGKTISNDDDVQKADVSST--------GQGVIDKDSLGPLLLQALD 122
Query: 125 GFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQL 175
GF VV+ +G I + S + YL + Q D+++ ++Y+ +H +DR+DF + L
Sbjct: 123 GFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNL 173
>gi|40254439 endothelial PAS domain protein 1 [Homo sapiens]
Length = 870
Score = 62.4 bits (150), Expect = 1e-09
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 19/163 (11%)
Query: 14 AGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDH-LASLLPFPPDIISKLDKLSVLR 72
A ++++R ++R EKS + R R E+ + LA LP P + S LDK S++R
Sbjct: 3 ADKEKKRSSSERRK----EKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMR 58
Query: 73 LSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSA 132
L++S+LR V ++ + A L L++L GF VV+
Sbjct: 59 LAISFLRTHKLLSSVCSENESEAEADQQMDN--------------LYLKALEGFIAVVTQ 104
Query: 133 EGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQL 175
+G + + S I ++G Q ++ +I+D+ H D ++ L
Sbjct: 105 DGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENL 147
>gi|30795242 aryl hydrocarbon receptor nuclear translocator isoform
3 [Homo sapiens]
Length = 774
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 35/204 (17%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S +R R+++ A + L+ ++P + K DKL++LR++VS+++ S
Sbjct: 80 SEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMK------------SL 127
Query: 94 QPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAE-GTIFYASATIVDYLGFHQT 152
+ + G P + L+LE+ +GF +VS E G + Y S ++ L Q+
Sbjct: 128 RGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQS 187
Query: 153 DVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLL-----RAQ 207
+ +YD +H DD Q L T ++A+ GR+L +
Sbjct: 188 EWFGSTLYDQVHPDDVDKLREQ-----------------LSTSENALTGRILDLKTGTVK 230
Query: 208 EWGTGTPTEYSAFLTRCFICRVRC 231
+ G + R FICR+RC
Sbjct: 231 KEGQQSSMRMCMGSRRSFICRMRC 254
>gi|30795240 aryl hydrocarbon receptor nuclear translocator isoform
2 [Homo sapiens]
Length = 328
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 35/204 (17%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S +R R+++ A + L+ ++P + K DKL++LR++VS+++ S
Sbjct: 95 SEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMK------------SL 142
Query: 94 QPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAE-GTIFYASATIVDYLGFHQT 152
+ + G P + L+LE+ +GF +VS E G + Y S ++ L Q+
Sbjct: 143 RGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQS 202
Query: 153 DVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLL-----RAQ 207
+ +YD +H DD Q L T ++A+ GR+L +
Sbjct: 203 EWFGSTLYDQVHPDDVDKLREQ-----------------LSTSENALTGRILDLKTGTVK 245
Query: 208 EWGTGTPTEYSAFLTRCFICRVRC 231
+ G + R FICR+RC
Sbjct: 246 KEGQQSSMRMCMGSRRSFICRMRC 269
>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
[Homo sapiens]
Length = 789
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 35/204 (17%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S +R R+++ A + L+ ++P + K DKL++LR++VS+++ S
Sbjct: 95 SEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMK------------SL 142
Query: 94 QPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAE-GTIFYASATIVDYLGFHQT 152
+ + G P + L+LE+ +GF +VS E G + Y S ++ L Q+
Sbjct: 143 RGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQS 202
Query: 153 DVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLL-----RAQ 207
+ +YD +H DD Q L T ++A+ GR+L +
Sbjct: 203 EWFGSTLYDQVHPDDVDKLREQ-----------------LSTSENALTGRILDLKTGTVK 245
Query: 208 EWGTGTPTEYSAFLTRCFICRVRC 231
+ G + R FICR+RC
Sbjct: 246 KEGQQSSMRMCMGSRRSFICRMRC 269
>gi|194097477 neuronal PAS domain protein 4 [Homo sapiens]
Length = 802
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/141 (31%), Positives = 69/141 (48%), Gaps = 16/141 (11%)
Query: 37 SKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPA 96
SK RD++NAE+ +L LLP +L L ++ L+ Y R FF A
Sbjct: 9 SKARRDQINAEIRNLKELLPLAEADKVRLSYLHIMSLACIYTRKGVFF-----------A 57
Query: 97 AGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMH 156
G P G + L+ + + ++ +L GF LV +AEG + Y S ++ ++LG D++
Sbjct: 58 GGTPLAGPTGLLSAQELED---IVAALPGFLLVFTAEGKLLYLSESVSEHLGHSMVDLVA 114
Query: 157 Q--NIYDYIHVDDRQDFCRQL 175
Q +IYD I D +QL
Sbjct: 115 QGDSIYDIIDPADHLTVRQQL 135
>gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Homo
sapiens]
Length = 717
Score = 57.4 bits (137), Expect = 5e-08
Identities = 48/204 (23%), Positives = 89/204 (43%), Gaps = 35/204 (17%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S +R R+++ + L+ ++P + K DKL++LR++VS+++ S
Sbjct: 69 SEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMK------------SM 116
Query: 94 QPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAE-GTIFYASATIVDYLGFHQT 152
+ + G P + L+LE+ +GF VV+AE G + Y S ++ L Q+
Sbjct: 117 RGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQS 176
Query: 153 DVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLL-----RAQ 207
+ +Y+ +H DD + QL T ++++ GR+L +
Sbjct: 177 EWFGSTLYEQVHPDDVEKLREQLC-----------------TSENSMTGRILDLKTGTVK 219
Query: 208 EWGTGTPTEYSAFLTRCFICRVRC 231
+ G + R FICR+RC
Sbjct: 220 KEGQQSSMRMCMGSRRSFICRMRC 243
>gi|31745180 aryl hydrocarbon receptor nuclear translocator-like 2
[Homo sapiens]
Length = 636
Score = 57.0 bits (136), Expect = 6e-08
Identities = 49/199 (24%), Positives = 89/199 (44%), Gaps = 26/199 (13%)
Query: 34 SNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSR 93
S KR RD++N ++ L++++P + KLDKL+VLR++V +LR S+
Sbjct: 113 SQTEKRRRDKMNNLIEELSAMIPQCNPMARKLDKLTVLRMAVQHLRSLKGLTNSYVGSNY 172
Query: 94 QPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAE-GTIFYASATIVDYLGFHQT 152
+P+ L + + L+L++ GF VV E G I + S ++ L + Q
Sbjct: 173 RPSF----------LQDNELRH--LILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQA 220
Query: 153 DVMHQNIYDYIHVDDRQDFCRQL-HWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWGT 211
+ Q+++D++H D QL + + P + + L+ + GR
Sbjct: 221 SLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGR--------- 271
Query: 212 GTPTEYSAFLTRCFICRVR 230
T + R F CR++
Sbjct: 272 ---TRVYSGSRRSFFCRIK 287
>gi|22027471 neuronal PAS domain protein 2 [Homo sapiens]
Length = 824
Score = 56.6 bits (135), Expect = 8e-08
Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 11/133 (8%)
Query: 31 AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ 90
A ++ K+ RD+ N + L+S+LP K+DK +VL +V F Q E
Sbjct: 12 ASRNKSEKKRRDQFNVLIKELSSMLP---GNTRKMDKTTVLE------KVIGFLQKHNEV 62
Query: 91 SSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFH 150
S++ L+ + L+LE+L+GF + V+ +G+I Y S +I LG
Sbjct: 63 SAQTEICDIQQDWKPSFLSNEEFTQ--LMLEALDGFIIAVTTDGSIIYVSDSITPLLGHL 120
Query: 151 QTDVMHQNIYDYI 163
+DVM QN+ +++
Sbjct: 121 PSDVMDQNLLNFL 133
>gi|4758010 clock [Homo sapiens]
Length = 846
Score = 52.8 bits (125), Expect = 1e-06
Identities = 36/131 (27%), Positives = 65/131 (49%), Gaps = 11/131 (8%)
Query: 33 KSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSS 92
++ K+ RD+ N + L S+LP K+DK +VL+ S+ +LR + S
Sbjct: 39 RNKSEKKRRDQFNVLIKELGSMLP---GNARKMDKSTVLQKSIDFLRKHKEITAQSDASE 95
Query: 93 RQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFHQT 152
+ D P S +L+LE+L+GF L + +G+I Y S ++ L +
Sbjct: 96 IRQ--------DWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPS 147
Query: 153 DVMHQNIYDYI 163
D++ Q+I+++I
Sbjct: 148 DLVDQSIFNFI 158
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,639,255
Number of Sequences: 37866
Number of extensions: 2066730
Number of successful extensions: 7459
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 7005
Number of HSP's gapped (non-prelim): 644
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.