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Search of human proteins with 115430211
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115430211 phosphatase and actin regulator 4 isoform 1 [Homo
sapiens]
(702 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115430211 phosphatase and actin regulator 4 isoform 1 [Homo s... 1409 0.0
gi|115430209 phosphatase and actin regulator 4 isoform 2 [Homo s... 1400 0.0
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s... 394 e-109
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s... 394 e-109
gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo s... 279 6e-75
gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo s... 279 6e-75
gi|54144631 phosphatase and actin regulator 1 [Homo sapiens] 261 2e-69
gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo sa... 218 1e-56
gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo sa... 218 1e-56
gi|34304356 phosphatase and actin regulator 3 isoform 3 [Homo sa... 214 2e-55
gi|116284392 mucin 2 precursor [Homo sapiens] 72 1e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 68 3e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 68 3e-11
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 68 3e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 67 7e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 67 7e-11
gi|110349719 titin isoform N2-A [Homo sapiens] 66 1e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 64 5e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 61 3e-09
gi|15529996 son of sevenless homolog 1 [Homo sapiens] 61 4e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 61 4e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 61 4e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni... 61 4e-09
gi|18959210 WIRE protein [Homo sapiens] 60 9e-09
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 59 1e-08
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 59 1e-08
gi|55741677 SET domain containing 1A [Homo sapiens] 59 2e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 59 2e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 59 2e-08
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 59 2e-08
>gi|115430211 phosphatase and actin regulator 4 isoform 1 [Homo
sapiens]
Length = 702
Score = 1409 bits (3648), Expect = 0.0
Identities = 702/702 (100%), Positives = 702/702 (100%)
Query: 1 MEDPFEEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKE 60
MEDPFEEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKE
Sbjct: 1 MEDPFEEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKE 60
Query: 61 TSEVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPV 120
TSEVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPV
Sbjct: 61 TSEVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPV 120
Query: 121 QVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHE 180
QVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHE
Sbjct: 121 QVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHE 180
Query: 181 ASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPAS 240
ASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPAS
Sbjct: 181 ASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPAS 240
Query: 241 TNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI 300
TNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI
Sbjct: 241 TNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI 300
Query: 301 PSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPP 360
PSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPP
Sbjct: 301 PSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPP 360
Query: 361 FPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIR 420
FPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIR
Sbjct: 361 FPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIR 420
Query: 421 IQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEE 480
IQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEE
Sbjct: 421 IQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEE 480
Query: 481 EEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDESYQSALAN 540
EEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDESYQSALAN
Sbjct: 481 EEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDESYQSALAN 540
Query: 541 KVKRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQ 600
KVKRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQ
Sbjct: 541 KVKRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQ 600
Query: 601 RNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRA 660
RNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRA
Sbjct: 601 RNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRA 660
Query: 661 DKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
DKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP
Sbjct: 661 DKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
>gi|115430209 phosphatase and actin regulator 4 isoform 2 [Homo
sapiens]
Length = 712
Score = 1400 bits (3623), Expect = 0.0
Identities = 698/700 (99%), Positives = 698/700 (99%)
Query: 3 DPFEEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETS 62
D EEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETS
Sbjct: 13 DAVEEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETS 72
Query: 63 EVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQV 122
EVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQV
Sbjct: 73 EVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQV 132
Query: 123 EEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEAS 182
EEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEAS
Sbjct: 133 EEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEAS 192
Query: 183 EGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTN 242
EGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTN
Sbjct: 193 EGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTN 252
Query: 243 TTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPS 302
TTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPS
Sbjct: 253 TTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPS 312
Query: 303 TSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFP 362
TSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFP
Sbjct: 313 TSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFP 372
Query: 363 AKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQ 422
AKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQ
Sbjct: 373 AKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQ 432
Query: 423 QALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE 482
QALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE
Sbjct: 433 QALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE 492
Query: 483 QTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDESYQSALANKV 542
QTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDESYQSALANKV
Sbjct: 493 QTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDESYQSALANKV 552
Query: 543 KRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN 602
KRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN
Sbjct: 553 KRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN 612
Query: 603 ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADK 662
ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADK
Sbjct: 613 ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADK 672
Query: 663 PWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
PWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP
Sbjct: 673 PWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 712
>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
sapiens]
Length = 634
Score = 394 bits (1012), Expect = e-109
Identities = 281/700 (40%), Positives = 361/700 (51%), Gaps = 99/700 (14%)
Query: 20 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV 79
D AG TPP KRK K S GKIFKPWKWRKKK+SDKF+ETS VLERKIS R+ REEL+
Sbjct: 17 DGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELI 76
Query: 80 KRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEE 139
+RGVL E P+Q G+ ++ NGH PIG EE R EE
Sbjct: 77 RRGVLKELPDQDGDVTVNFENS---NGHMIPIG-----------EESTR---------EE 113
Query: 140 DLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI 199
++ K GS V E P PL E QA+D +
Sbjct: 114 NVVKSEEGNGS--------VSEKTP---------PL-------EEQAEDKKEN------- 142
Query: 200 ISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHM------- 252
T + T AA +L + P P P+ P P A+ +
Sbjct: 143 -----TENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
Query: 253 -VPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESA 311
P KQ P+PPPKPA RN+ A S + + + SP P S T+ S
Sbjct: 198 KAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSK 257
Query: 312 AAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPE 371
A T T +R ++ P+ +H+ + + K
Sbjct: 258 AG-TVGTTKGKR-----------------KTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
Query: 372 IEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPM 431
+E S L Q +P E+Q K ++ P PPLPL + A +P+ +
Sbjct: 300 VE---SFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVL 356
Query: 432 TPILEGSHRAHSLLFENSDSFSEDSS---TLGRTRSLPITIEMLKVPDDEEEEEQTCPST 488
+ G+ S L + ++E+ + TL L + E K +EE +T P
Sbjct: 357 VSV--GADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 414
Query: 489 FSEE-MTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDE----SYQSALANKVK 543
+ M +S + E + +DSDS+GPI Y D+EDEDE S +SALA+K++
Sbjct: 415 LTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIR 474
Query: 544 RKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN 602
R+DTLA+KL +RPS+ EL + N S+EE EIR QIG L+RRLSQRPT EELEQRN
Sbjct: 475 RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRN 534
Query: 603 ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADK 662
IL+ KNE + Q K E+KRRL+RKLS RPTVAEL AR+ILRFNEYVEVTD+ DYDRRADK
Sbjct: 535 ILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADK 594
Query: 663 PWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
PW +LTPADKAAIRKELNEFKS+EMEVHEES+ FTR+HRP
Sbjct: 595 PWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
sapiens]
Length = 645
Score = 394 bits (1012), Expect = e-109
Identities = 281/700 (40%), Positives = 361/700 (51%), Gaps = 99/700 (14%)
Query: 20 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV 79
D AG TPP KRK K S GKIFKPWKWRKKK+SDKF+ETS VLERKIS R+ REEL+
Sbjct: 28 DGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELI 87
Query: 80 KRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEE 139
+RGVL E P+Q G+ ++ NGH PIG EE R EE
Sbjct: 88 RRGVLKELPDQDGDVTVNFENS---NGHMIPIG-----------EESTR---------EE 124
Query: 140 DLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI 199
++ K GS V E P PL E QA+D +
Sbjct: 125 NVVKSEEGNGS--------VSEKTP---------PL-------EEQAEDKKEN------- 153
Query: 200 ISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHM------- 252
T + T AA +L + P P P+ P P A+ +
Sbjct: 154 -----TENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 208
Query: 253 -VPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESA 311
P KQ P+PPPKPA RN+ A S + + + SP P S T+ S
Sbjct: 209 KAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSK 268
Query: 312 AAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPE 371
A T T +R ++ P+ +H+ + + K
Sbjct: 269 AG-TVGTTKGKR-----------------KTDKQPITSHLSSDTTTSGTSDLKGEPAETR 310
Query: 372 IEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPM 431
+E S L Q +P E+Q K ++ P PPLPL + A +P+ +
Sbjct: 311 VE---SFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVL 367
Query: 432 TPILEGSHRAHSLLFENSDSFSEDSS---TLGRTRSLPITIEMLKVPDDEEEEEQTCPST 488
+ G+ S L + ++E+ + TL L + E K +EE +T P
Sbjct: 368 VSV--GADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 425
Query: 489 FSEE-MTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDE----SYQSALANKVK 543
+ M +S + E + +DSDS+GPI Y D+EDEDE S +SALA+K++
Sbjct: 426 LTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIR 485
Query: 544 RKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN 602
R+DTLA+KL +RPS+ EL + N S+EE EIR QIG L+RRLSQRPT EELEQRN
Sbjct: 486 RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRN 545
Query: 603 ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADK 662
IL+ KNE + Q K E+KRRL+RKLS RPTVAEL AR+ILRFNEYVEVTD+ DYDRRADK
Sbjct: 546 ILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADK 605
Query: 663 PWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
PW +LTPADKAAIRKELNEFKS+EMEVHEES+ FTR+HRP
Sbjct: 606 PWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 645
>gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo
sapiens]
Length = 554
Score = 279 bits (714), Expect = 6e-75
Identities = 192/462 (41%), Positives = 258/462 (55%), Gaps = 29/462 (6%)
Query: 260 IPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPP----KRGIPSTSVPTLESAAAIT 315
IP + + R N V +E +S+ +PPL K+ S S T S A+ +
Sbjct: 103 IPIGEESTREENVVKSE-----EGNGSVSEKTPPLEEQAEDKKAGSSHSKKTTGSKASAS 157
Query: 316 TKT------PSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVV 369
T P +E + G+ ++ P+ +H+ + + K
Sbjct: 158 PSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAE 217
Query: 370 PEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPL 429
+E S L Q +P E+Q K ++ P PPLPL + A +P+
Sbjct: 218 TRVE---SFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPV 274
Query: 430 PMTPILEGSHRAHSLLFENSDSFSEDSS---TLGRTRSLPITIEMLKVPDDEEEEEQTCP 486
+ + G+ S L + ++E+ + TL L + E K +EE +T P
Sbjct: 275 VLVSV--GADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVP 332
Query: 487 STFSEE-MTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDE----SYQSALANK 541
+ M +S + E + +DSDS+GPI Y D+EDEDE S +SALA+K
Sbjct: 333 QLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASK 392
Query: 542 VKRKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQ 600
++R+DTLA+KL +RPS+ EL + N S+EE EIR QIG L+RRLSQRPT EELEQ
Sbjct: 393 IRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQ 452
Query: 601 RNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRA 660
RNIL+ KNE + Q K E+KRRL+RKLS RPTVAEL AR+ILRFNEYVEVTD+ DYDRRA
Sbjct: 453 RNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRA 512
Query: 661 DKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
DKPW +LTPADKAAIRKELNEFKS+EMEVHEES+ FTR+HRP
Sbjct: 513 DKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 554
Score = 126 bits (316), Expect = 8e-29
Identities = 106/340 (31%), Positives = 151/340 (44%), Gaps = 29/340 (8%)
Query: 20 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV 79
D AG TPP KRK K S GKIFKPWKWRKKK+SDKF+ETS VLERKIS R+ REEL+
Sbjct: 17 DGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELI 76
Query: 80 KRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIG--NARSSSPVQVEEEPVRLASLRKAIP 137
+RGVL E P+Q G+ ++ NGH PIG + R + V+ EE ++ +
Sbjct: 77 RRGVLKELPDQDGDVTVNFENS---NGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLE 133
Query: 138 EEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTAR 197
E+ K+ GS+ S+ + + K P SS +AS+ + GT +
Sbjct: 134 EQAEDKKAGSSHSKKTTGS--------KASASPSTSSTSSRPKASKETVSSKAGTVGTTK 185
Query: 198 FIISTSITTAPAATTAATSLAKTVNLSVTPSPA-------PRTLPAAPASTNTTATPSLT 250
T + ++ T+ + T +L P+ +T+P A NT S+
Sbjct: 186 GKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGA-EEQNTGKFKSMV 244
Query: 251 HMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI---PSTSVPT 307
P P P P + A + + P L P + + T+ T
Sbjct: 245 PPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTT 304
Query: 308 LESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPL 347
L S + S RE + C E L P+ +P L
Sbjct: 305 LYSGTGL-----SVNRENAKCFTTKEELGKTVPQLLTPGL 339
>gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo
sapiens]
Length = 565
Score = 279 bits (714), Expect = 6e-75
Identities = 192/462 (41%), Positives = 258/462 (55%), Gaps = 29/462 (6%)
Query: 260 IPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPP----KRGIPSTSVPTLESAAAIT 315
IP + + R N V +E +S+ +PPL K+ S S T S A+ +
Sbjct: 114 IPIGEESTREENVVKSE-----EGNGSVSEKTPPLEEQAEDKKAGSSHSKKTTGSKASAS 168
Query: 316 TKT------PSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVV 369
T P +E + G+ ++ P+ +H+ + + K
Sbjct: 169 PSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAE 228
Query: 370 PEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPL 429
+E S L Q +P E+Q K ++ P PPLPL + A +P+
Sbjct: 229 TRVE---SFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPV 285
Query: 430 PMTPILEGSHRAHSLLFENSDSFSEDSS---TLGRTRSLPITIEMLKVPDDEEEEEQTCP 486
+ + G+ S L + ++E+ + TL L + E K +EE +T P
Sbjct: 286 VLVSV--GADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVP 343
Query: 487 STFSEE-MTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDE----SYQSALANK 541
+ M +S + E + +DSDS+GPI Y D+EDEDE S +SALA+K
Sbjct: 344 QLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASK 403
Query: 542 VKRKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQ 600
++R+DTLA+KL +RPS+ EL + N S+EE EIR QIG L+RRLSQRPT EELEQ
Sbjct: 404 IRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQ 463
Query: 601 RNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRA 660
RNIL+ KNE + Q K E+KRRL+RKLS RPTVAEL AR+ILRFNEYVEVTD+ DYDRRA
Sbjct: 464 RNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRA 523
Query: 661 DKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
DKPW +LTPADKAAIRKELNEFKS+EMEVHEES+ FTR+HRP
Sbjct: 524 DKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 565
Score = 126 bits (316), Expect = 8e-29
Identities = 106/340 (31%), Positives = 151/340 (44%), Gaps = 29/340 (8%)
Query: 20 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV 79
D AG TPP KRK K S GKIFKPWKWRKKK+SDKF+ETS VLERKIS R+ REEL+
Sbjct: 28 DGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELI 87
Query: 80 KRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIG--NARSSSPVQVEEEPVRLASLRKAIP 137
+RGVL E P+Q G+ ++ NGH PIG + R + V+ EE ++ +
Sbjct: 88 RRGVLKELPDQDGDVTVNFENS---NGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLE 144
Query: 138 EEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTAR 197
E+ K+ GS+ S+ + + K P SS +AS+ + GT +
Sbjct: 145 EQAEDKKAGSSHSKKTTGS--------KASASPSTSSTSSRPKASKETVSSKAGTVGTTK 196
Query: 198 FIISTSITTAPAATTAATSLAKTVNLSVTPSPA-------PRTLPAAPASTNTTATPSLT 250
T + ++ T+ + T +L P+ +T+P A NT S+
Sbjct: 197 GKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGA-EEQNTGKFKSMV 255
Query: 251 HMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI---PSTSVPT 307
P P P P + A + + P L P + + T+ T
Sbjct: 256 PPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTT 315
Query: 308 LESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPL 347
L S + S RE + C E L P+ +P L
Sbjct: 316 LYSGTGL-----SVNRENAKCFTTKEELGKTVPQLLTPGL 350
>gi|54144631 phosphatase and actin regulator 1 [Homo sapiens]
Length = 580
Score = 261 bits (666), Expect = 2e-69
Identities = 177/381 (46%), Positives = 222/381 (58%), Gaps = 42/381 (11%)
Query: 343 PSPPLPTHIPPEPPR-TPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQK-------KEV 394
P P P +P P + +PP P K + + P L L Q+ Q+ +
Sbjct: 221 PDPGAPVKLPCLPVKLSPPLPPKKVMICMPVG-GPDLSLVSYTAQKSGQQGVAQHHHTVL 279
Query: 395 PKRILDQ-NFGE--PHIPSRLPPLPLH---IRIQQALTSPLPMT-PILEGSHRAH--SLL 445
P +I Q +G H+PS LP+H R+ L L MT LE S + S
Sbjct: 280 PSQIQHQLQYGSHGQHLPSTTGSLPMHPSGCRMIDELNKTLAMTMQRLESSEQRVPCSTS 339
Query: 446 FENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQC 505
+ +S S D T LP ++ V + ++ ++ P E + C
Sbjct: 340 YHSSGLHSGDGVTKAGPMGLPEIRQVPTVVIECDDNKENVPHESDYEDS---------SC 390
Query: 506 L--REEEEKESDSDSEGPIQYRDEEDEDESYQSALANKVKRKDTLAMKLNHRPSEPELN- 562
L REEEE+E D E+D+ Y S+LA KV RKD+LA+KL++RPS+ EL
Sbjct: 391 LYTREEEEEEED-----------EDDDSSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEE 439
Query: 563 LNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRNILQPKNEADRQAEKREIKRR 622
N P ++ EE E+R QIG L RRLSQRPT EELEQRNIL+P+NE + Q EKREIKRR
Sbjct: 440 KNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRR 499
Query: 623 LTRKLSQRPTVAELLARKIL-RFNEYVEVTDAQDYDRRADKPWTKLTPADKAAIRKELNE 681
LTRKLSQRPTV EL RKIL RF++YVEV DAQDYDRRADKPWT+LT ADKAAIRKELNE
Sbjct: 500 LTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNE 559
Query: 682 FKSSEMEVHEESKHFTRYHRP 702
FKS+EMEVHE S+H TR+HRP
Sbjct: 560 FKSTEMEVHELSRHLTRFHRP 580
Score = 109 bits (272), Expect = 1e-23
Identities = 68/154 (44%), Positives = 90/154 (58%), Gaps = 5/154 (3%)
Query: 20 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV 79
DS+ G TPP +R+SKF+ G+IFKPWKWRKKKS +KFK TS LERKISMR+ REEL+
Sbjct: 96 DSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKS-EKFKHTSAALERKISMRQSREELI 154
Query: 80 KRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEE 139
KRGVL E ++ GE + L+NG + + +++ S P E EPV + R E
Sbjct: 155 KRGVLKEIYDKDGELSISNEEDSLENGQS--LSSSQLSLPALSEMEPVPMP--RDPCSYE 210
Query: 140 DLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKR 173
L+ G P + + V P LPPK+
Sbjct: 211 VLQPSDIMDGPDPGAPVKLPCLPVKLSPPLPPKK 244
>gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo
sapiens]
Length = 518
Score = 218 bits (556), Expect = 1e-56
Identities = 157/417 (37%), Positives = 218/417 (52%), Gaps = 42/417 (10%)
Query: 301 PSTSVPTLESAAAITTKTPSDEREK-----STCSMGSELLPMISPRSPSPPLPTHIP--P 353
P +S L+ AA + + + +E + +T + L S SP PL + P
Sbjct: 129 PLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLP 188
Query: 354 EPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVP--KRILDQNFGEPHIPSR 411
PP P P K + ++ + Q K P + L G PH+ +
Sbjct: 189 SPPLLPTPPPKASSKTTK-----NVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTT- 242
Query: 412 LPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEM 471
+ PLP + ++E HRA + DSF S + L + +
Sbjct: 243 -------------VHRPLPPSRVIEELHRALATK-HRQDSFQGRESKGSPKKRLDVRLSR 288
Query: 472 LKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKES----DSDSEGPIQYRDE 527
+ +E E+ + E T+ EE KE+ + + Y+DE
Sbjct: 289 TSSVERGKEREEAWSFDGALENKRTAA-------KESEENKENLIINSELKDDLLLYQDE 341
Query: 528 EDEDESYQSALANKVKRKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLI 586
E ++S S + +K+ LA+KL +RPS+ EL + N +P ++ EE EIR QI L
Sbjct: 342 EALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLS 401
Query: 587 RRLSQRPTPEELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKIL-RFN 645
+RLSQRP EELE+RNIL+ +N+ Q E+REIK+RLTRKL+QRPTV EL RKIL RF+
Sbjct: 402 KRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFS 461
Query: 646 EYVEVTDAQDYDRRADKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
+YVEV AQDYDRRADKPWT+L+ ADKAAIRKELNE+KS+EMEVH SKH TR+HRP
Sbjct: 462 DYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
Score = 90.9 bits (224), Expect = 4e-18
Identities = 82/281 (29%), Positives = 126/281 (44%), Gaps = 45/281 (16%)
Query: 24 AGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGV 83
+G TPP +R SK + G+IFKPWKWRKKK ++K K+T+ LE+K++ R+ REEL+K+G
Sbjct: 14 SGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMAGRQGREELIKKG- 71
Query: 84 LLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKK 143
LLE EQ E + P G RS V+ EP S +
Sbjct: 72 LLEMMEQDAE-----------SKTCNPDGGPRS-----VQSEPPTPKS-----------E 104
Query: 144 RLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSG--GTARFIIS 201
L S +QP S + + V +PLSS+ + + SSG A ++
Sbjct: 105 TLTSEDAQPGSPLATGTDQVSL------DKPLSSAAHLDDAAKMPSASSGEEADAGSLLP 158
Query: 202 TS--ITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPP 259
T+ ++ A A + S + + SV P+P LP P ++ T ++T Q
Sbjct: 159 TTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQ-- 216
Query: 260 IPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI 300
+ ++++P + L+ PLPP R I
Sbjct: 217 ----ASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVI 253
>gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo
sapiens]
Length = 559
Score = 218 bits (556), Expect = 1e-56
Identities = 157/417 (37%), Positives = 218/417 (52%), Gaps = 42/417 (10%)
Query: 301 PSTSVPTLESAAAITTKTPSDEREK-----STCSMGSELLPMISPRSPSPPLPTHIP--P 353
P +S L+ AA + + + +E + +T + L S SP PL + P
Sbjct: 170 PLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLP 229
Query: 354 EPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVP--KRILDQNFGEPHIPSR 411
PP P P K + ++ + Q K P + L G PH+ +
Sbjct: 230 SPPLLPTPPPKASSKTTK-----NVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTT- 283
Query: 412 LPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEM 471
+ PLP + ++E HRA + DSF S + L + +
Sbjct: 284 -------------VHRPLPPSRVIEELHRALATK-HRQDSFQGRESKGSPKKRLDVRLSR 329
Query: 472 LKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKES----DSDSEGPIQYRDE 527
+ +E E+ + E T+ EE KE+ + + Y+DE
Sbjct: 330 TSSVERGKEREEAWSFDGALENKRTAA-------KESEENKENLIINSELKDDLLLYQDE 382
Query: 528 EDEDESYQSALANKVKRKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLI 586
E ++S S + +K+ LA+KL +RPS+ EL + N +P ++ EE EIR QI L
Sbjct: 383 EALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLS 442
Query: 587 RRLSQRPTPEELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKIL-RFN 645
+RLSQRP EELE+RNIL+ +N+ Q E+REIK+RLTRKL+QRPTV EL RKIL RF+
Sbjct: 443 KRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFS 502
Query: 646 EYVEVTDAQDYDRRADKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
+YVEV AQDYDRRADKPWT+L+ ADKAAIRKELNE+KS+EMEVH SKH TR+HRP
Sbjct: 503 DYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 559
Score = 93.6 bits (231), Expect = 6e-19
Identities = 86/303 (28%), Positives = 133/303 (43%), Gaps = 49/303 (16%)
Query: 2 EDPFEEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKET 61
E+P E P P ++ + TPP +R SK + G+IFKPWKWRKKK ++K K+T
Sbjct: 37 ENPDEMDQTPPARPEYLVSGIR----TPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQT 91
Query: 62 SEVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQ 121
+ LE+K++ R+ REEL+K+G LLE EQ E + P G RS
Sbjct: 92 TSALEKKMAGRQGREELIKKG-LLEMMEQDAE-----------SKTCNPDGGPRS----- 134
Query: 122 VEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEA 181
V+ EP S + L S +QP S + + V +PLSS+
Sbjct: 135 VQSEPPTPKS-----------ETLTSEDAQPGSPLATGTDQVSL------DKPLSSAAHL 177
Query: 182 SEGQAKDATSSG--GTARFIISTS--ITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAA 237
+ + SSG A ++ T+ ++ A A + S + + SV P+P LP
Sbjct: 178 DDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTP 237
Query: 238 PASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPK 297
P ++ T ++T Q + ++++P + L+ PLPP
Sbjct: 238 PPKASSKTTKNVTGQATLFQ------ASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPS 291
Query: 298 RGI 300
R I
Sbjct: 292 RVI 294
>gi|34304356 phosphatase and actin regulator 3 isoform 3 [Homo
sapiens]
Length = 448
Score = 214 bits (546), Expect = 2e-55
Identities = 131/281 (46%), Positives = 174/281 (61%), Gaps = 14/281 (4%)
Query: 428 PLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPS 487
PLP + ++E HRA + DSF S + L + + + +E E+
Sbjct: 176 PLPPSRVIEELHRALATK-HRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSF 234
Query: 488 TFSEEMTPTSVIPKLPQCLREEEEKES----DSDSEGPIQYRDEEDEDESYQSALANKVK 543
+ E T+ EE KE+ + + Y+DEE ++S S +
Sbjct: 235 DGALENKRTAA-------KESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKC 287
Query: 544 RKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN 602
+K+ LA+KL +RPS+ EL + N +P ++ EE EIR QI L +RLSQRP EELE+RN
Sbjct: 288 KKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRN 347
Query: 603 ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKIL-RFNEYVEVTDAQDYDRRAD 661
IL+ +N+ Q E+REIK+RLTRKL+QRPTV EL RKIL RF++YVEV AQDYDRRAD
Sbjct: 348 ILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRAD 407
Query: 662 KPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
KPWT+L+ ADKAAIRKELNE+KS+EMEVH SKH TR+HRP
Sbjct: 408 KPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 448
Score = 79.7 bits (195), Expect = 8e-15
Identities = 65/189 (34%), Positives = 92/189 (48%), Gaps = 30/189 (15%)
Query: 24 AGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGV 83
+G TPP +R SK + G+IFKPWKWRKKK ++K K+T+ LE+K++ R+ REEL+K+G
Sbjct: 14 SGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMAGRQGREELIKKG- 71
Query: 84 LLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKK 143
LLE EQ E + P G RS V+ EP S +
Sbjct: 72 LLEMMEQDAE-----------SKTCNPDGGPRS-----VQSEPPTPKS-----------E 104
Query: 144 RLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTS 203
L S +QP S + + V L L + +A+ QA S+ + R +ST
Sbjct: 105 TLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAGQATLFQASSMKSADPSLRGQLSTP 164
Query: 204 ITTAPAATT 212
T +P TT
Sbjct: 165 -TGSPHLTT 172
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 72.4 bits (176), Expect = 1e-12
Identities = 72/275 (26%), Positives = 96/275 (34%), Gaps = 27/275 (9%)
Query: 108 TTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPP 167
TTP S P+ P P + +T + P + S P P PP
Sbjct: 1430 TTPPPTTTPSPPITTTTTPP---------PTTTPSPPISTTTTPPPTTTPSPPTTTPSPP 1480
Query: 168 LLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAA--TSLAKTVNLSV 225
P P +++ + S T S TT P TT + T+ T +
Sbjct: 1481 TTTPSPPTTTT---TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTT 1537
Query: 226 TPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGT 285
TPSP P T P P ++ TT P+ T P PPP S P S + T
Sbjct: 1538 TPSP-PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP--SPPTTTTPSPPTITTT 1594
Query: 286 L---LSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRS 342
+ PSPP P T+ P+ + IT T ST ++ P P +
Sbjct: 1595 TPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT-------STTTLPPTTTPSPPPTT 1647
Query: 343 PSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPS 377
+ P PT P P T P P T P PS
Sbjct: 1648 TTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682
Score = 70.5 bits (171), Expect = 5e-12
Identities = 75/271 (27%), Positives = 94/271 (34%), Gaps = 31/271 (11%)
Query: 110 PIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPP-- 167
PI + P P S P +T + P + S P P P
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTT----TTTTPPPTTTPSPPTTTPITPPA 1512
Query: 168 ---LLPPKRPLSSSHEASEGQAKDATSSGGTARFIIS-TSITTAPAATTAA--TSLAKTV 221
LPP S + T S T I TS TT P TT + + T
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572
Query: 222 NLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAI 281
+ TPSP T P+ P T TT P+ T P PPP S P ++
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT--PSPPTTTPITPPT 1630
Query: 282 NSGTL--LSKPSPP-----LPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSEL 334
++ TL + PSPP PP PS T S TT TP S+
Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS------- 1683
Query: 335 LPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
P+ + +PSPP T P P TP P T
Sbjct: 1684 -PITT--TPSPPTTTMTTPSPTTTPSSPITT 1711
Score = 70.5 bits (171), Expect = 5e-12
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 33/229 (14%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAA--TSL 217
P P PP P P +S+ T T T+ TT P TT + T+
Sbjct: 1535 PTTTPSPPTTTPITPPTST----------TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584
Query: 218 AKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPK-----PAHRNSNP 272
+ T +P P T P+ P +T TT P+ T P P PP P S P
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644
Query: 273 VIAELSQ---AINSGTLLSKPSPPL-----PPKRGIPSTSVPTLESAAAITTKTPSDERE 324
+ S + PSPP+ PP PS+ + T S T TPS
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSP--- 1701
Query: 325 KSTCSMGSELLPMISPRS---PSPPLPTHIPPEPPRTPPFPAKTFQVVP 370
T + S + +P S PSPP T P P TP P T +P
Sbjct: 1702 --TTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP 1748
Score = 65.1 bits (157), Expect = 2e-10
Identities = 69/234 (29%), Positives = 90/234 (38%), Gaps = 23/234 (9%)
Query: 147 STGSQPNSEAESVPENVPK--PPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSI 204
ST + P + S P PP P P +++ S T T +T+
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT--PSPPTITTTTPPPTTTPSPPTTTT 1609
Query: 205 TTAPAATTAA--TSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPP 262
TT P TT + T+ T S T P P T P+ P +T TT P+ T P P PP
Sbjct: 1610 TTPPPTTTPSPPTTTPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1668
Query: 263 ------PKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVP---TLESAAA 313
P P S+P+ S T ++ PSP P I +T+ P T S
Sbjct: 1669 ITTTTTPPPTTTPSSPITTTPSPPT---TTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725
Query: 314 ITTKTPSDEREKSTCSMGSELLPMISPRSP--SPPLPTHIPPEPPRTPPFPAKT 365
T TPS S + LP + SP + PLP I P P PF T
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP--PTFSPFSTTT 1777
Score = 63.9 bits (154), Expect = 5e-10
Identities = 70/261 (26%), Positives = 86/261 (32%), Gaps = 43/261 (16%)
Query: 158 SVPENVPKPP-----LLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITT-APAAT 211
S P P PP LPP S + T S TT +P +
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459
Query: 212 TAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPP--------- 262
T T T T +P+P T +P +T TT P T P PI P
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPP 1519
Query: 263 -------------PKPAHRNSNPVIAELSQAINSGTL--LSKPSPP-----LPPKRGIPS 302
P P S P ++ ++ TL + PSPP PP PS
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1579
Query: 303 TSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPE------PP 356
T S ITT TP S + + P + +PSPP T I P PP
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTLPP 1637
Query: 357 RTPPFPAKTFQVVPEIEFPPS 377
T P P T P PS
Sbjct: 1638 TTTPSPPPTTTTTPPPTTTPS 1658
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/213 (25%), Positives = 72/213 (33%), Gaps = 47/213 (22%)
Query: 205 TTAPAATTAATSLAKTVNLSVTPSPA--------------------------PRTLPAAP 238
T +P TT + T L T +P+ P T P+ P
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457
Query: 239 ASTNTTATPSLTHMVPAKQP------PIPP------PKPAHRNSNPVIAELSQAINSGTL 286
ST TT P+ T P P P PP P P S P ++ ++ TL
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL 1517
Query: 287 --LSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPS 344
+ PSPP P T+ P+ + IT T ST ++ P P + +
Sbjct: 1518 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT-------STTTLPPTTTPSPPPTTTT 1570
Query: 345 PPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPS 377
P PT P P T P P P PS
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Score = 50.8 bits (120), Expect = 4e-06
Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 19/220 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4107
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 4108 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTP 4165
Query: 275 AELSQAINSGTLLSKPSP--PLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGS 332
+ T ++ + P P G T PT S A I T S+ +S+ S
Sbjct: 4166 TPTGTQTPTTTPITTTTTVTPTPTPTGT-QTGPPTHTSTAPIAELTTSNPPPESSTPQTS 4224
Query: 333 ELLPMISPRSPSPPLPTHIPPE-------PPRTPPFPAKT 365
SP + S L + +PP PP TP P T
Sbjct: 4225 RSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262
Score = 46.6 bits (109), Expect = 8e-05
Identities = 45/203 (22%), Positives = 72/203 (35%), Gaps = 8/203 (3%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITT--APAATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 4117 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4176
Query: 218 AKTVNLSVTPSPAPR-TLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI-- 274
T +VTP+P P T P T+T LT P P P+ + S+P+
Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNP--PPESSTPQTSRSTSSPLTES 4234
Query: 275 AELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSEL 334
L + ++ +PP P ++ TL + TT P +T S
Sbjct: 4235 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 4294
Query: 335 LP-MISPRSPSPPLPTHIPPEPP 356
P + + S PT P P
Sbjct: 4295 TPSTVQTTTTSAWTPTPTPLSTP 4317
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 2118
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 2176
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 2177 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2204
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2139 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2198
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 2256
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 2314
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 2315 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2342
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 2337 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 2394
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 2395 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 2452
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 2453 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2480
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 2475 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 2532
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 2533 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 2590
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 2591 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2618
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2612
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 2670
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 2728
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 2729 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2756
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2750
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 2751 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 2808
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 2866
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 2867 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2894
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2888
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 2889 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 2946
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3004
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3005 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3032
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 3084
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 3085 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3142
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3143 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3170
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3164
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3165 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 3222
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 3223 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3280
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3281 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3308
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3302
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3303 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 3360
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 3361 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3418
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3419 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3446
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3440
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 3498
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 3499 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3556
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3557 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3584
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3579 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 3636
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 3637 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3694
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3695 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3722
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3716
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3717 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 3774
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 3775 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3832
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3833 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3860
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3854
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3855 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 3912
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 3913 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 3970
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 3971 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 3998
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/214 (21%), Positives = 75/214 (35%), Gaps = 18/214 (8%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992
Query: 218 AKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVI 274
T +VTP+P P +T P +T TT TP+ T Q P P P
Sbjct: 3993 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTP 4050
Query: 275 AELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKTPSDEREKSTCSMG 331
+ T ++ + P P G + T+ P + T TP+ + +T
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 4108
Query: 332 SELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
I+ + P PT + P T P T
Sbjct: 4109 ------ITTTTTVTPTPTPTGTQTPTTTPITTTT 4136
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/167 (23%), Positives = 59/167 (35%), Gaps = 16/167 (9%)
Query: 205 TTAPAATTAATSLAKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQPPIP 261
T P T T+ T +VTP+P P +T P +T TT TP+ T Q P
Sbjct: 1910 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTT 1967
Query: 262 PPKPAHRNSNPVIAELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAITTKT 318
P P + T ++ + P P G + T+ P + T T
Sbjct: 1968 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027
Query: 319 PSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
P+ + +T I+ + P PT + P T P T
Sbjct: 2028 PTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2066
Score = 40.4 bits (93), Expect = 0.006
Identities = 41/171 (23%), Positives = 61/171 (35%), Gaps = 16/171 (9%)
Query: 201 STSITTAPAATTAATSLAKTVNLSVTPSPAP---RTLPAAPASTNTTATPSLTHMVPAKQ 257
+T TT T T+ T +VTP+P P +T P +T TT TP+ T Q
Sbjct: 1883 TTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQ 1940
Query: 258 PPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPS--PPLPPKRGIPS-TSVPTLESAAAI 314
P P P + T ++ + P P G + T+ P +
Sbjct: 1941 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2000
Query: 315 TTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T TP+ + +T I+ + P PT + P T P T
Sbjct: 2001 PTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITTTT 2043
Score = 39.3 bits (90), Expect = 0.013
Identities = 48/238 (20%), Positives = 76/238 (31%), Gaps = 27/238 (11%)
Query: 150 SQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA 209
+QP + + EN P P P++++ + T + T +T++T P
Sbjct: 1880 TQPTTMTTTTTEN----PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1935
Query: 210 --ATTAATSLAKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMV 253
T T+ T +VTP+P P T+ P T T +
Sbjct: 1936 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1995
Query: 254 PAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT--- 307
P P P + I + + T +P P+ + T PT
Sbjct: 1996 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2055
Query: 308 LESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
+ ITT T T + P I+ + P PT + P T P T
Sbjct: 2056 TPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 2112
Score = 38.5 bits (88), Expect = 0.021
Identities = 60/294 (20%), Positives = 92/294 (31%), Gaps = 36/294 (12%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4038
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 4039 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4098
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDER 323
+ I T + P P P+T+ P + T TP+ +
Sbjct: 4099 TGTQTPTTTPIT---------TTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQ 4148
Query: 324 EKST--CSMGSELLPMISPRSPSPPLPTHIPPEPPRTP-PFPAKTFQVVP-EIEFPPSLD 379
+T + + + P +P P T I TP P P T P P +
Sbjct: 4149 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAE 4208
Query: 380 LHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTP 433
L P E + + + S LPP I+ T+P P TP
Sbjct: 4209 LTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP-----AIEMTSTAP-PSTP 4256
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2106
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2166
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 2227 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 2273
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2304
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2364
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 2365 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 2411
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 2383 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2442
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 2503 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 2549
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 2521 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2580
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2640
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 2641 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 2687
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2718
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 2779 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 2825
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2796
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 2797 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2856
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 2857 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2916
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 2917 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 2963
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 2935 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2994
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 3055 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 3101
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3132
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3192
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 3193 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 3239
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3330
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 3331 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 3377
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 3349 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3408
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3468
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 3469 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 3515
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 3487 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3546
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3606
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 3607 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 3653
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 3625 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3684
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3744
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 3745 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 3791
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3762
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3822
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3882
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 3883 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 3929
Score = 37.0 bits (84), Expect = 0.062
Identities = 45/228 (19%), Positives = 70/228 (30%), Gaps = 23/228 (10%)
Query: 160 PENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPA--ATTAATSL 217
P P P P++++ + T + T +T++T P T T+
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3900
Query: 218 AKTVNLSVTPSPAPR--------------TLPAAPASTNTTATPSLTHMVPAKQPPIPPP 263
T +VTP+P P T+ P T T + P P P
Sbjct: 3901 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3960
Query: 264 KPAHRNSNPVIAELSQAINSGTLLSKPSP---PLPPKRGIPSTSVPT---LESAAAITTK 317
+ I + + T +P P+ + T PT + ITT
Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4020
Query: 318 TPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T T + P I+ + P PT + P T P T
Sbjct: 4021 TTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 4067
Score = 36.2 bits (82), Expect = 0.11
Identities = 35/148 (23%), Positives = 55/148 (37%), Gaps = 14/148 (9%)
Query: 109 TPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPK--- 165
TP G ++ P P+ + PE + ST S P +E+ ++ +P
Sbjct: 4189 TPTGT-QTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSS-PLTESTTLLSTLPPAIE 4246
Query: 166 -----PPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKT 220
PP P +S TS GT +T ++AP +T T T
Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQT----T 4302
Query: 221 VNLSVTPSPAPRTLPAAPASTNTTATPS 248
+ TP+P P + P+ +T PS
Sbjct: 4303 TTSAWTPTPTPLSTPSIIRTTGLRPYPS 4330
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 68.2 bits (165), Expect = 3e-11
Identities = 90/368 (24%), Positives = 137/368 (37%), Gaps = 75/368 (20%)
Query: 71 MRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLA 130
+R EE V RG E P++ G D +S P P
Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARRD---------------TSGPTPGTPSPAMAR 169
Query: 131 SLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDAT 190
R A E L + P P+PP P++ +SS+ E S + A
Sbjct: 170 RSRAAGTEVGLPR--------------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 215
Query: 191 ----SSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTAT 246
S+GG + S S++++ T +S A++ P+ R P APA +
Sbjct: 216 RRRPSAGGGLQRPASRSLSSS---ATPLSSPARS-------GPSARGTPRAPAHPSQPKP 265
Query: 247 PSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVP 306
L + P P + PP+ +++ P + LS + L+ PSP PP P P
Sbjct: 266 KGLQALRP---PQVTPPR---KDAAPALGPLSSSP-----LATPSPSAPPSPSAP----P 310
Query: 307 TLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTF 366
+L++ + PS ++T S+GS L PSPPL P PP+ PP A
Sbjct: 311 SLQTLPSPPATPPS----QATTSLGSPTLQATHSFLPSPPLSPLATP-PPQAPPALA--- 362
Query: 367 QVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALT 426
+P ++ PPS + + P + P P PP+ QA
Sbjct: 363 --LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-------QAPF 413
Query: 427 SPLPMTPI 434
SP P+
Sbjct: 414 SPPASPPV 421
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/330 (23%), Positives = 116/330 (35%), Gaps = 39/330 (11%)
Query: 95 PGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNS 154
P K + L ++P+ S+P P SL+ +P +T S +
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP----SLQ-TLPSPPATPPSQATTSLGSP 333
Query: 155 EAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAA 214
++ +P PPL P P + A A S A +S T +P A A
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-PASPPLSPLATPSPQAPNAL 392
Query: 215 TSLAKTVNLSVTPSPA-------PRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAH 267
S PSP P + P +P++T + P P + PP PP P
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452
Query: 268 RNSNPVIAELSQAINSGTL-LSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKS 326
S + + + L L+KP P P P+ + P L++ + P
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAP-----PALATPPLQALPSPPASFPGQ----- 502
Query: 327 TCSMGSELLPMISPRSPSPPLP-THIPPEPPRTPP-FPAKTFQVVPEIEFPPSLDLHQEI 384
+P SPS LP + + PP+ PP A QV P P+L +
Sbjct: 503 ------------APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550
Query: 385 PQQ-EDQKKEVPKRILDQNFGEPHIPSRLP 413
P D P+ L G P PSR P
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580
Score = 48.9 bits (115), Expect = 2e-05
Identities = 78/284 (27%), Positives = 101/284 (35%), Gaps = 47/284 (16%)
Query: 116 SSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKP----PLL-- 169
+S PV P A A P L+ S P S + + P P P PL
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474
Query: 170 --PPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTA--ATSLAKTVNLSV 225
PP+ P + + + S G A F S S+ +P AT A + L V
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534
Query: 226 TPSP-------APRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELS 278
PSP APR P P + + P LT + PP P P+ S P +A
Sbjct: 535 PPSPPASPTLQAPRR-PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG-- 591
Query: 279 QAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMI 338
+S + S P RG S E AA +P + E + C P
Sbjct: 592 ---HSSSATSTPE----ELRGYDSGP----EGGAA---ASPPPDAELAACH------PAA 631
Query: 339 SPRSPSPPL-----PTHIPPEPPRTPPFPAKTFQVVPEIEFPPS 377
R P+PPL P P PP T P A + E E P S
Sbjct: 632 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 675
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 67.8 bits (164), Expect = 3e-11
Identities = 93/379 (24%), Positives = 140/379 (36%), Gaps = 95/379 (25%)
Query: 71 MRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLA 130
+R EE V RG E P++ G D +S P P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRD---------------TSGPTPGTPSPAMAR 178
Query: 131 SLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDAT 190
R A E L + P P+PP P++ +SS+ E S + A
Sbjct: 179 RSRAAGTEVGLPR--------------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224
Query: 191 ----SSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTAT 246
S+GG + S S++++ T +S A++ P+ R P APA +
Sbjct: 225 RRRPSAGGGLQRPASRSLSSS---ATPLSSPARS-------GPSARGTPRAPAHPSQPKP 274
Query: 247 PSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSP------PLPPKRGI 300
L + P P + PP+ +++ P + LS + L+ PSP P+PP
Sbjct: 275 KGLQALRP---PQVTPPR---KDAAPALGPLSSSP-----LATPSPSGTKARPVPPPDNA 323
Query: 301 PSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPP 360
+ TL + + T P ++P SPS P P PP TPP
Sbjct: 324 ATPLPATLPPSPPLATPLP------------------LAPPSPSAPPSLQTLPSPPATPP 365
Query: 361 FPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIR 420
A P ++ PPSL Q IP +VP + + + PP PL +
Sbjct: 366 SQAPPSMTTPPMQAPPSL---QTIP-----PIQVPHSLTSPSL-------QAPPSPLALS 410
Query: 421 IQQALTSPLPMTPILEGSH 439
QA TS +P L+ +H
Sbjct: 411 SLQATTS--LGSPTLQATH 427
Score = 62.4 bits (150), Expect = 1e-09
Identities = 72/333 (21%), Positives = 111/333 (33%), Gaps = 25/333 (7%)
Query: 108 TTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPP 167
+TP + +P+ + P SL A+ L L Q S S P
Sbjct: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAV--SPLSSPLTIHPLQALSSLASHSPQAPLSS 506
Query: 168 LLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTP 227
L+ P PL + + + +S T S+ P T +A + P
Sbjct: 507 LIMP--PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP 564
Query: 228 SPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLL 287
+P P P +P +T TPS P + PP P +P ++ L
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP----------L 614
Query: 288 SKPSPPLPPKRGIPSTSVPTLESA----AAITTKTPSDEREKSTCSMGSELLPMISPRSP 343
+ P P PP +P P A + + T +P + + + P SP
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 344 SPPLPTHIPP-EPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQN 402
+P P PP P TPP A P ++ PPS + + P +
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 403 FGEPHIPSRLPPLPLHIRIQQALTSPLPMTPIL 435
P P PP+ + T P + P+L
Sbjct: 735 LQVPPSPPASPPM------SPSATPPPRVPPLL 761
Score = 49.7 bits (117), Expect = 9e-06
Identities = 67/236 (28%), Positives = 88/236 (37%), Gaps = 39/236 (16%)
Query: 158 SVPENVPKPPLL--PPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTA-- 213
S P ++P PL PP+ P + + + S G A F S S+ +P AT
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 214 ATSLAKTVNLSVTPSP-------APRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPA 266
A + L V PSP APR P P + + P LT + PP P P+
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRR-PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889
Query: 267 HRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKS 326
S P +A +S + S P RG S E AA +P + E +
Sbjct: 890 STLSGPDLAG-----HSSSATSTPE----ELRGYDSGP----EGGAA---ASPPPDAELA 933
Query: 327 TCSMGSELLPMISPRSPSPPL-----PTHIPPEPPRTPPFPAKTFQVVPEIEFPPS 377
C P R P+PPL P P PP T P A + E E P S
Sbjct: 934 ACH------PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 983
Score = 48.1 bits (113), Expect = 3e-05
Identities = 69/274 (25%), Positives = 92/274 (33%), Gaps = 61/274 (22%)
Query: 152 PNSEAESVPENVP-KPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAA 210
P S S P P PP PP P S A S + S +P
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSP-------SATPPSQAPPSLAAPPLQVPPSPPASPPM 716
Query: 211 TTAATSLAKTVN------LSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPK 264
+ +AT + L V PSP P + P +P++T P L P + PP PP
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSP-PASPPMSPSATPPPRVPPLLAAPPLQVPPSPP-- 773
Query: 265 PAHRNSNPVIAELSQAINSGTLLSKPSPPL--PPKRGIPSTSVPTLESAAAITTKTPSDE 322
S P PL PP + P+ + P L++ + P
Sbjct: 774 ----------------------ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ- 810
Query: 323 REKSTCSMGSELLPMISPRSPSPPLP-THIPPEPPRTPP-FPAKTFQVVPEIEFPPSLDL 380
+P SPS LP + + PP+ PP A QV P P+L
Sbjct: 811 ----------------APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 381 HQEIPQQ-EDQKKEVPKRILDQNFGEPHIPSRLP 413
+ P D P+ L G P PSR P
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 67.8 bits (164), Expect = 3e-11
Identities = 81/325 (24%), Positives = 129/325 (39%), Gaps = 34/325 (10%)
Query: 97 KPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTG---SQPN 153
+PS + + +G S++P + + SL+ +P+E ++ L + G S P
Sbjct: 665 QPSPGLASSPEKIVLGQPPSATPTAILTQD----SLQMFLPQERSQQPLSAEGPHLSVPA 720
Query: 154 SEAESVPENVPKP-PLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATT 212
S S P P P P + +A + QA A + A + P+++
Sbjct: 721 SVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP---GPSSSP 777
Query: 213 AATSLAKTVNLSVTPSPAPRTLPAAPAST--NTTATPSLTHMVPAKQPPIPPPKPAHRNS 270
+ A + PSP P P+ P S + + PS + P P PP P
Sbjct: 778 SLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVI 837
Query: 271 NPVIAELSQAINSG-TLLSKPSPPLPPKRGIPSTSVP--------TLESAAAITTKTPSD 321
+ A N T P PPL P+ P +P + SA A +++T S
Sbjct: 838 QNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSR 897
Query: 322 EREKSTCSMGSELLPMISP-RSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDL 380
+ + P P +SP+PP H+ PEP PP P +TFQ+V FP
Sbjct: 898 LPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMV-TTPFP----- 951
Query: 381 HQEIPQQE---DQKKEVPKRILDQN 402
+PQ + ++ +VP I+ QN
Sbjct: 952 --ALPQPKALLERFHQVPSGIILQN 974
Score = 40.8 bits (94), Expect = 0.004
Identities = 74/317 (23%), Positives = 113/317 (35%), Gaps = 54/317 (17%)
Query: 162 NVPKPPLLPPKRPLSSSHEASEGQAKDAT-SSGGT----ARFIISTSITTAPAATTAATS 216
N P LL + P+S ++ G ++ T +S G A +I +++ A A T S
Sbjct: 246 NTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNS 305
Query: 217 LAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPA-HRNSNPVIA 275
+ + P+ P P A A P L P +P P HR P+
Sbjct: 306 VFGGAGAASAPTGTPSGQPLAVA-------PGL-----GSSPLVPAPNVILHRTPTPI-- 351
Query: 276 ELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELL 335
Q +G L K L PK P+ + T++ + P + + + G
Sbjct: 352 ---QPKPAGVLPPKLYQ-LTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQ 407
Query: 336 PMISPRSPSPPLPTHIPPEPPRT-----PPFPAKTFQ--------------VVPEIEFPP 376
++ P+P L ++ +PP T PP P V+P P
Sbjct: 408 NVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLP 467
Query: 377 SLD--LHQEIP--QQEDQKKEVPKRILDQNF--GEPHIPSRLPPLPLHIRIQQALTSPLP 430
+ L P Q Q +P + Q PH +L P I Q L PL
Sbjct: 468 GQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANP--ILTNQNLAGPLS 525
Query: 431 MTPIL---EGSHRAHSL 444
+ P+L G+H AH L
Sbjct: 526 LGPVLAPHSGAHSAHIL 542
Score = 38.1 bits (87), Expect = 0.028
Identities = 39/167 (23%), Positives = 66/167 (39%), Gaps = 15/167 (8%)
Query: 268 RNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTP-SDEREKS 326
R S+ + + S + + +L + P+P + P + T E+ + I K E S
Sbjct: 1263 RASSSLSSSSSSSSAASSLDADEDGPMPSRNRPP---IKTYEARSRIGLKLKIKQEAGLS 1319
Query: 327 TCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQ 386
+ L P+ P P PP + PPR PP P T Q+ ++ PP ++
Sbjct: 1320 KVVHNTALDPVHQP--PPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLG 1377
Query: 387 QEDQKKEVP-KRILDQNFGEPHIPSRLP--------PLPLHIRIQQA 424
+P ++ +N G P P P P PL ++ +A
Sbjct: 1378 TAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEA 1424
Score = 36.2 bits (82), Expect = 0.11
Identities = 103/473 (21%), Positives = 149/473 (31%), Gaps = 108/473 (22%)
Query: 126 PVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKP----PLLPPKRPLSSSHEA 181
P +L++L + + L TG Q + +N+ P P+L P S+H
Sbjct: 483 PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHIL 542
Query: 182 SE-----GQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNL-----SVTPSPAP 231
S GQ A + T APA AAT++ + V L ++ +P
Sbjct: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGP-AATTVLQGVTLPPSAVAMLNTPDG 601
Query: 232 RTLPAAPASTNTTATPSLT-----HMVPAKQPPIP---------------------PPKP 265
PA PA+ A P LT PA P+P PP+
Sbjct: 602 LVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQA 661
Query: 266 AHRNSNPVIAELSQAI---------------------------------NSGTLLSKP-- 290
+P +A + I G LS P
Sbjct: 662 TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721
Query: 291 ---SPPLPPKRGIPSTSV----------PTLESAAAITTKTPSDEREKSTCSMGSELLPM 337
S P P + P+T V P +++ A + P+ K S LP
Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 338 ISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKR 397
+P SP LP+ P PP PP ++ + PPS P +
Sbjct: 782 QAPLGDSPHLPSPHPTRPPSRPPSRPQS------VSRPPSEPPLHPCPPPQAPPTLPGIF 835
Query: 398 ILDQNFGEPHIPSRL------PPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDS 451
++ G P S PP P Q PLP P L S + ++ S
Sbjct: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVA-----S 890
Query: 452 FSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQ 504
SE SS L P ++ P + T P T P + P P+
Sbjct: 891 SSETSSRL--PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPR 941
Score = 31.2 bits (69), Expect = 3.4
Identities = 35/128 (27%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 164 PKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNL 223
P P L PK L H+ G + G A STS+ P + AA+ L
Sbjct: 949 PFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL--GPLTSPAASVLVS---- 1002
Query: 224 SVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINS 283
AP P AP+ P+ M PP+ P + SN +++A +S
Sbjct: 1003 ----GQAPSGTPTAPSH-----APAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASS 1053
Query: 284 GTLLSKPS 291
G KPS
Sbjct: 1054 GP--GKPS 1059
Score = 30.8 bits (68), Expect = 4.5
Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 20/157 (12%)
Query: 109 TPIGNARSSSPV----QVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPN-SEAESVPENV 163
TP G AR SP +V+E L A+ +E ++ L +P S A+ +
Sbjct: 1404 TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPD 1463
Query: 164 PKPPLLPP-KRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVN 222
+ P LPP KR S S + + + T + ++I + +N
Sbjct: 1464 WEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSI-------------LN 1510
Query: 223 LSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPP 259
L P P AS T A+P H P PP
Sbjct: 1511 LQQAPGRTPAPSYPHAASAGTPASPPPLHR-PEAYPP 1546
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 66.6 bits (161), Expect = 7e-11
Identities = 138/629 (21%), Positives = 209/629 (33%), Gaps = 71/629 (11%)
Query: 21 SVEAGDTTPPTKRKSKFSGFGKIF--KPWKWRKKKSSDKFKETSEVLERKISMRKPREEL 78
+VE +TT K+ S G K K + +K S+ TS+VL + P+ E
Sbjct: 149 TVETKETTTTNKQTST-DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT----PKAET 203
Query: 79 VKRGVLLEDP---------EQGGEDPGKPSDAMLKNGHTTPIGNA----RSSSPVQVEEE 125
+G L P E P +P+ +K+ TTP A +S+ E
Sbjct: 204 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 263
Query: 126 PVRLASLRKAIPEEDLKKRLG-----STGSQPNSEAESVPENVPKPPLLPPKRPLSSSHE 180
P P+E +T S P + E P KP PK P ++ +
Sbjct: 264 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 323
Query: 181 -----ASEGQAKDATSSGGTARFIISTSITTAPAATT---AATSLAKTVNLSVTPSPAPR 232
+ A T + + PA TT A + K + T P+P
Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP- 382
Query: 233 TLPAAPASTNTTATPSLTH---MVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSK 289
T P PA T T + P+ T K P P +P+ + A + + T K
Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP-APTTPKEPAPTTPKK 441
Query: 290 PSP-------PLPPKRGIPSTS---VPTLESAAAITT-KTPSDEREKSTCSMGSELLPMI 338
P+P P PK P+T+ PT A TT K + K E L
Sbjct: 442 PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 339 SPRSPSPPLPTHIPPEPPR--TPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPK 396
+P P+P P + P P TP P + P+ P + + P K+ P
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT----PKEPAPTTPKEPAPT 557
Query: 397 RILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDS 456
+ P P P L P P TP + S + D
Sbjct: 558 TPKEP---APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614
Query: 457 STLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKE-SD 515
+ T P +E T P + PT++ P ++ KE +
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTP----KGTAPTTLKEPAPTTPKKPAPKELAP 670
Query: 516 SDSEGPIQYRDEEDEDESYQSALANKVKRKDTLAMKLNHRPSEPE-----LNLNSWPCKS 570
+ ++GP ++ + + K K P+ PE + S P +
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETPPPTTSEVSTPTTT 729
Query: 571 KEEWNEIRHQIGNTLIRRLSQRPTPEELE 599
KE H+ + LS PTP+ LE
Sbjct: 730 KEP--TTIHKSPDESTPELSAEPTPKALE 756
Score = 60.1 bits (144), Expect = 7e-09
Identities = 118/493 (23%), Positives = 169/493 (34%), Gaps = 69/493 (13%)
Query: 23 EAGDTTP--PTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV- 79
E TTP PT K +P K+ + KE + +K + P+E
Sbjct: 316 EPAPTTPKEPTPTTPK--------EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367
Query: 80 --KRGVLLEDPEQGGEDPGKPSDAMLKNGHTT---PIGNARSSSPVQVEE-EPVRLASLR 133
K E P +P+ K+ TT P S+P +E P
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 427
Query: 134 KAIPEEDL----KKRLGSTGSQP--NSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAK 187
P+E KK +T +P + E P KP PK P ++ + +
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 487
Query: 188 DATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAP--ASTNTTA 245
+ + +T AP T LA T TP+ P P A+ NT
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 544
Query: 246 TPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSV 305
P+ T P + P P +PA A + + T L +P+P P K
Sbjct: 545 EPAPT--TPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKK-------- 593
Query: 306 PTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEP-PRTPPFPAK 364
P + A TTK P+ +TC +P +P PT P EP P TP PA
Sbjct: 594 PAPKELAPTTTKEPT----STTCDKP-------APTTPKGTAPT-TPKEPAPTTPKEPAP 641
Query: 365 TFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQA 424
T P+ P +L + P KK PK + P + P P +
Sbjct: 642 T---TPKGTAPTTL----KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 694
Query: 425 LT--SPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE 482
T P P TP + E + + ST T+ P TI K PD+ E
Sbjct: 695 TTPKEPAPTTP-----KKPAPTTPETPPPTTSEVSTPTTTKE-PTTIH--KSPDESTPEL 746
Query: 483 QTCPSTFSEEMTP 495
P+ + E +P
Sbjct: 747 SAEPTPKALENSP 759
Score = 50.4 bits (119), Expect = 5e-06
Identities = 55/225 (24%), Positives = 82/225 (36%), Gaps = 16/225 (7%)
Query: 152 PNSE-AESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAA 210
PNS+ ++ V K + K +++ + S + TS+ T +++ AP +
Sbjct: 132 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 191
Query: 211 ------TTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPK 264
T A + K L+ P P T P PAST TP K P P +
Sbjct: 192 KVLAKPTPKAETTTKGPALTTPKEPTPTT-PKEPAST----TPKEPTPTTIKSAPTTPKE 246
Query: 265 PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDERE 324
PA + + + T P+ P P PT +A T K P+
Sbjct: 247 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306
Query: 325 KSTCSMGSELLPMISPRSPSPPLPTHIPP---EP-PRTPPFPAKT 365
K + +P+ P+P P P EP P TP PA T
Sbjct: 307 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351
Score = 39.3 bits (90), Expect = 0.013
Identities = 69/343 (20%), Positives = 109/343 (31%), Gaps = 31/343 (9%)
Query: 95 PGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNS 154
P KP+ L T + S P + + ++ P K + + P +
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 719
Query: 155 EAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI--ISTSITTAPAATT 212
+E K P K P S+ E S A + + T T P TT
Sbjct: 720 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 779
Query: 213 AATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPS--------------LTHMVPAKQP 258
A +L T P T AAP T TAT + +T
Sbjct: 780 TAKDKTTERDLRTT----PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 835
Query: 259 PIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKT 318
P P + + I + +++KP PK T A +
Sbjct: 836 PFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK------DRATNSKATTPKPQK 889
Query: 319 PSDEREKSTCSMGSELLPMI-SPR-SPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPP 376
P+ +K T + + +P + P+ +P+P T PE T Q P
Sbjct: 890 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 949
Query: 377 SLDLHQEIPQQED---QKKEVPKRILDQNFGEPHIPSRLPPLP 416
+ L + P+ ED + E P +L + P + + LP
Sbjct: 950 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 992
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 66.6 bits (161), Expect = 7e-11
Identities = 138/629 (21%), Positives = 209/629 (33%), Gaps = 71/629 (11%)
Query: 21 SVEAGDTTPPTKRKSKFSGFGKIF--KPWKWRKKKSSDKFKETSEVLERKISMRKPREEL 78
+VE +TT K+ S G K K + +K S+ TS+VL + P+ E
Sbjct: 190 TVETKETTTTNKQTST-DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT----PKAET 244
Query: 79 VKRGVLLEDP---------EQGGEDPGKPSDAMLKNGHTTPIGNA----RSSSPVQVEEE 125
+G L P E P +P+ +K+ TTP A +S+ E
Sbjct: 245 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 304
Query: 126 PVRLASLRKAIPEEDLKKRLG-----STGSQPNSEAESVPENVPKPPLLPPKRPLSSSHE 180
P P+E +T S P + E P KP PK P ++ +
Sbjct: 305 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 364
Query: 181 -----ASEGQAKDATSSGGTARFIISTSITTAPAATT---AATSLAKTVNLSVTPSPAPR 232
+ A T + + PA TT A + K + T P+P
Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP- 423
Query: 233 TLPAAPASTNTTATPSLTH---MVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSK 289
T P PA T T + P+ T K P P +P+ + A + + T K
Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP-APTTPKEPAPTTPKK 482
Query: 290 PSP-------PLPPKRGIPSTS---VPTLESAAAITT-KTPSDEREKSTCSMGSELLPMI 338
P+P P PK P+T+ PT A TT K + K E L
Sbjct: 483 PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 339 SPRSPSPPLPTHIPPEPPR--TPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPK 396
+P P+P P + P P TP P + P+ P + + P K+ P
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT----PKEPAPTTPKEPAPT 598
Query: 397 RILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDS 456
+ P P P L P P TP + S + D
Sbjct: 599 TPKEP---APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655
Query: 457 STLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKE-SD 515
+ T P +E T P + PT++ P ++ KE +
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTP----KGTAPTTLKEPAPTTPKKPAPKELAP 711
Query: 516 SDSEGPIQYRDEEDEDESYQSALANKVKRKDTLAMKLNHRPSEPE-----LNLNSWPCKS 570
+ ++GP ++ + + K K P+ PE + S P +
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETPPPTTSEVSTPTTT 770
Query: 571 KEEWNEIRHQIGNTLIRRLSQRPTPEELE 599
KE H+ + LS PTP+ LE
Sbjct: 771 KEP--TTIHKSPDESTPELSAEPTPKALE 797
Score = 60.1 bits (144), Expect = 7e-09
Identities = 118/493 (23%), Positives = 169/493 (34%), Gaps = 69/493 (13%)
Query: 23 EAGDTTP--PTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV- 79
E TTP PT K +P K+ + KE + +K + P+E
Sbjct: 357 EPAPTTPKEPTPTTPK--------EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408
Query: 80 --KRGVLLEDPEQGGEDPGKPSDAMLKNGHTT---PIGNARSSSPVQVEE-EPVRLASLR 133
K E P +P+ K+ TT P S+P +E P
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 468
Query: 134 KAIPEEDL----KKRLGSTGSQP--NSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAK 187
P+E KK +T +P + E P KP PK P ++ + +
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 528
Query: 188 DATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAP--ASTNTTA 245
+ + +T AP T LA T TP+ P P A+ NT
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 585
Query: 246 TPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSV 305
P+ T P + P P +PA A + + T L +P+P P K
Sbjct: 586 EPAPT--TPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKK-------- 634
Query: 306 PTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEP-PRTPPFPAK 364
P + A TTK P+ +TC +P +P PT P EP P TP PA
Sbjct: 635 PAPKELAPTTTKEPT----STTCDKP-------APTTPKGTAPT-TPKEPAPTTPKEPAP 682
Query: 365 TFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQA 424
T P+ P +L + P KK PK + P + P P +
Sbjct: 683 T---TPKGTAPTTL----KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 735
Query: 425 LT--SPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE 482
T P P TP + E + + ST T+ P TI K PD+ E
Sbjct: 736 TTPKEPAPTTP-----KKPAPTTPETPPPTTSEVSTPTTTKE-PTTIH--KSPDESTPEL 787
Query: 483 QTCPSTFSEEMTP 495
P+ + E +P
Sbjct: 788 SAEPTPKALENSP 800
Score = 50.4 bits (119), Expect = 5e-06
Identities = 55/225 (24%), Positives = 82/225 (36%), Gaps = 16/225 (7%)
Query: 152 PNSE-AESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAA 210
PNS+ ++ V K + K +++ + S + TS+ T +++ AP +
Sbjct: 173 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 232
Query: 211 ------TTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPK 264
T A + K L+ P P T P PAST TP K P P +
Sbjct: 233 KVLAKPTPKAETTTKGPALTTPKEPTPTT-PKEPAST----TPKEPTPTTIKSAPTTPKE 287
Query: 265 PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDERE 324
PA + + + T P+ P P PT +A T K P+
Sbjct: 288 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347
Query: 325 KSTCSMGSELLPMISPRSPSPPLPTHIPP---EP-PRTPPFPAKT 365
K + +P+ P+P P P EP P TP PA T
Sbjct: 348 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392
Score = 39.3 bits (90), Expect = 0.013
Identities = 69/343 (20%), Positives = 109/343 (31%), Gaps = 31/343 (9%)
Query: 95 PGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNS 154
P KP+ L T + S P + + ++ P K + + P +
Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 760
Query: 155 EAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI--ISTSITTAPAATT 212
+E K P K P S+ E S A + + T T P TT
Sbjct: 761 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 820
Query: 213 AATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPS--------------LTHMVPAKQP 258
A +L T P T AAP T TAT + +T
Sbjct: 821 TAKDKTTERDLRTT----PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 876
Query: 259 PIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKT 318
P P + + I + +++KP PK T A +
Sbjct: 877 PFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK------DRATNSKATTPKPQK 930
Query: 319 PSDEREKSTCSMGSELLPMI-SPR-SPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPP 376
P+ +K T + + +P + P+ +P+P T PE T Q P
Sbjct: 931 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 990
Query: 377 SLDLHQEIPQQED---QKKEVPKRILDQNFGEPHIPSRLPPLP 416
+ L + P+ ED + E P +L + P + + LP
Sbjct: 991 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 1033
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 65.9 bits (159), Expect = 1e-10
Identities = 142/634 (22%), Positives = 231/634 (36%), Gaps = 84/634 (13%)
Query: 63 EVLERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQV 122
E+ E+ I +KP ++V R E + P P +++ P P +V
Sbjct: 10444 EISEKIIPPKKPPTKVVPR------KEPPAKVPEVPKKIVVEEKVRVP--EEPRVPPTKV 10495
Query: 123 EEE-PVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEA 181
E P + K +P KK P + E VPE K P+ PPK+P +
Sbjct: 10496 PEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEK--KVPVPPPKKPEVPPTKV 10553
Query: 182 SEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPAST 241
E K A I + P A + V P P P T
Sbjct: 10554 PE-VPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEV-------VPEKKVPAAPPKKPEVT 10605
Query: 242 NTTATPSLTHMVPAKQPPIPPPK-----PAHRNSNPVIAELSQAINSGTLLSKPSPPLPP 296
+ +VP K+ P+PPPK P P +A + + P P PP
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAI---PPKPESPP 10662
Query: 297 KRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPT-HIPPEP 355
LE A + P + P+ P P + +
Sbjct: 10663 PEVFEEPEEVALEEPPAEVVEEPEPAAPPQV---------TVPPKKPVPEKKAPAVVAKK 10713
Query: 356 PRTPP--FPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRIL-DQNFGEPHIPSRL 412
P PP P +VVPE + P + E P + EVPK ++ ++ P P +
Sbjct: 10714 PELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPA--KVPEVPKEVVPEKKVAVPKKP-EV 10770
Query: 413 PPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEML 472
PP + ++ + P P+ E + ++E + + + E
Sbjct: 10771 PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPE--------EEK 10822
Query: 473 KVPDDEEEEEQTCPSTFSEEMTPTSVIP--KLPQCLREE----EEKESDSDSEGP-IQYR 525
VP EEEE + P EE P +IP K+P + E +E E + E P ++ R
Sbjct: 10823 PVPVAEEEEPEVPPPAVPEE--PKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880
Query: 526 DEEDEDESYQSALANKV-KRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNT 584
+ + K+ + K K+ +P PE K E ++ G
Sbjct: 10881 PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPE----------KVELTPLKVPGGEK 10930
Query: 585 LIRRL--SQRPTP-EELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKI 641
+R+L ++P P EE+ +++L+ + E E+ +++ + K+ ++P V E K
Sbjct: 10931 KVRKLLPERKPEPKEEVVLKSVLRKRPE----EEEPKVEPKKLEKV-KKPAVPEPPPPKP 10985
Query: 642 LRFNEYVEVTDAQDYDRRADKPWTKLTPADKAAI 675
+ E VEV +R+ +P TK+ P K AI
Sbjct: 10986 V---EEVEVPTVTKRERKIPEP-TKV-PEIKPAI 11014
Score = 50.4 bits (119), Expect = 5e-06
Identities = 96/511 (18%), Positives = 188/511 (36%), Gaps = 96/511 (18%)
Query: 252 MVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESA 311
++P K P +P KP PV P+P K+ P VP +
Sbjct: 9945 VIPVKVPEVPR-KPVPEEKKPV-------------------PVPKKKEAPPAKVPEVPKK 9984
Query: 312 AAITTKTPSDEREKSTCSMGSELLPMISPRSPSP-PLPTHIPPEPPRTPPFPAKTF--QV 368
++EK + E+ P P P+P + P + P P K +
Sbjct: 9985 PEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044
Query: 369 VP-----EIEFPPSL--DLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRI 421
VP ++E PP+ ++ +++ +E + VPK++ P +P + P+P+ + +
Sbjct: 10045 VPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV---EAPPPKVPKKREPVPVPVAL 10101
Query: 422 QQA--LTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLP-----ITIEMLKV 474
Q + + P E +L E + E+ L +P + E V
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYV 10161
Query: 475 PDDEE--EEEQTCPSTF------------------------SEEMTPTSVIPKLPQCLRE 508
P++EE EE+ P +E P + +P++P+ + E
Sbjct: 10162 PEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEE 10221
Query: 509 -------EEE----KESDSDSEGPIQYRDEEDEDESYQSALANKVKR-KDTLAMKLNHRP 556
EEE + ++ E PI + +E S + R + + + P
Sbjct: 10222 KRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAP 10281
Query: 557 SEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRP-----TPEELEQRNILQPKNEAD 611
+ + + P K ++ E + + +++ P P+++ ++ +L PK EA
Sbjct: 10282 TPVPKKVEAPPAKVSKKIPEEKVPVP---VQKKEAPPAKVPEVPKKVPEKKVLVPKKEAV 10338
Query: 612 RQAEKREI-KRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADKPWTKLTPA 670
A+ R + + +++ Q V E L +EV +A+ + ++ + ++
Sbjct: 10339 PPAKGRTVLEEKVSVAFRQEVVVKERLE---------LEVVEAEVEEIPEEEEFHEVEEY 10389
Query: 671 DKAAIRKELNEFKSSEMEVHEESKHFTRYHR 701
+ E+ EF E EE + HR
Sbjct: 10390 FEEGEFHEVEEFIKLEQHRVEEEHRVEKVHR 10420
Score = 45.4 bits (106), Expect = 2e-04
Identities = 76/363 (20%), Positives = 127/363 (34%), Gaps = 62/363 (17%)
Query: 225 VTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAE---LSQAI 281
V P P A PA A P VP + PPP V E +S
Sbjct: 9798 VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITK 9857
Query: 282 NSGTLLSKPSP--PLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMG-------- 331
+++P+ P+ PKR + VP A + P +E +
Sbjct: 9858 REKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTH 9917
Query: 332 ----------------------SELLPMIS------PRSPSP------PLPTHIPPEPPR 357
E++P+I PR P P P+P P +
Sbjct: 9918 VEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAK 9977
Query: 358 TPPFPAKTFQ----VVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLP 413
P P K + ++P+ E PP + E+P++ +++VP + + P P+++P
Sbjct: 9978 VPEVPKKPEEKVPVLIPKKEKPPPAKV-PEVPKKPVPEEKVPVPV-PKKVEAP--PAKVP 10033
Query: 414 PLPLHIRIQQALTSPLPM---TPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIE 470
+P ++ + P P P + L+ E +P E
Sbjct: 10034 EVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE 10093
Query: 471 MLKVPDDEEEEEQTCPSTFSEEMTP-TSVIPKLPQCLREEEEKESDSDSEGPIQYRDEED 529
+ VP +EE+ F EE+ P V+P+ + L EEEE + + P + +
Sbjct: 10094 PVPVPVALPQEEEV---LFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPE 10150
Query: 530 EDE 532
E+E
Sbjct: 10151 EEE 10153
Score = 40.8 bits (94), Expect = 0.004
Identities = 47/233 (20%), Positives = 93/233 (39%), Gaps = 37/233 (15%)
Query: 287 LSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSP- 345
+++P P+P K +P VPT A +++L P P
Sbjct: 9786 ITEPEKPIPVKP-VPEEPVPTKPKAPP------------------AKVLKKAVPEEKVPV 9826
Query: 346 PLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQN--- 402
P+P + P PP+ P P K F+ +I + +++ + + PKR++ +
Sbjct: 9827 PIPKKLKPPPPKVPEEPKKVFE--EKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVP 9884
Query: 403 --FGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLG 460
E P R+P +P + ++ +T H L+ E + E+ +
Sbjct: 9885 VPRKEVAPPVRVPEVPKELEPEEVAFEEEVVT------HVEEYLVEEEEEYIHEEEEFIT 9938
Query: 461 RTRSLP-ITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEK 512
+P I +++ +VP EE+ ++ P + +P++P ++ EEK
Sbjct: 9939 EEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVP---KKPEEK 9988
Score = 34.7 bits (78), Expect = 0.31
Identities = 54/270 (20%), Positives = 78/270 (28%), Gaps = 47/270 (17%)
Query: 95 PGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEED-------------- 140
P P +L+ P+ S P +V EEP +A + PEE+
Sbjct: 10776 PEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVP 10835
Query: 141 -------------------LKKRLGSTGSQPNSEAE-SVPENVPKPPLLPPKRPLSSSHE 180
+KK +P E P+ P+PP PP P E
Sbjct: 10836 PPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKE 10895
Query: 181 ASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRT-----LP 235
Q K + + + P + + P P L
Sbjct: 10896 KIF-QLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLR 10954
Query: 236 AAPASTNTTATPSLTHMV--PAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSP- 292
P P V PA P PPPKP P + + + I T + + P
Sbjct: 10955 KRPEEEEPKVEPKKLEKVKKPAVPEP-PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA 11013
Query: 293 ---PLPPKRGIPSTSVPTLESAAAITTKTP 319
P P + P V T++ TP
Sbjct: 11014 IPLPAPEPKPKPEAEVKTIKPPPVEPEPTP 11043
Score = 34.3 bits (77), Expect = 0.40
Identities = 63/291 (21%), Positives = 102/291 (35%), Gaps = 48/291 (16%)
Query: 253 VPAKQPPIPPPKPAHRNSNPVIAELSQA----------INSGTLLSKPSPPLPPKRGIPS 302
VPAK P P P PVI ++ + + +SK P P R
Sbjct: 9165 VPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQ 9224
Query: 303 TSVPTLESAAAITTKTPSDEREKSTCSMGSELLPM------------------ISPRSPS 344
V ++ A T K E + S E + + IS R
Sbjct: 9225 EEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEP 9284
Query: 345 PP----LPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILD 400
PP LP PE P P K P++ P + +P +E + VPK+
Sbjct: 9285 PPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPK----KPVP-EEKKPVPVPKK--- 9336
Query: 401 QNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLG 460
EP P ++P +P ++ + P+P+ E + + + + +
Sbjct: 9337 ----EPAAPPKVPEVPKKPVPEEKI--PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ 9390
Query: 461 RTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEE 511
R S P + ++P + EE+ EE+ P +P LP+ EE+
Sbjct: 9391 REESPPPAVP--EIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEK 9439
Score = 33.1 bits (74), Expect = 0.90
Identities = 80/382 (20%), Positives = 139/382 (36%), Gaps = 37/382 (9%)
Query: 301 PSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPP 360
P+ E + K P+ E + ++ + P+P PP+ P
Sbjct: 9551 PAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPE 9610
Query: 361 FPAKTFQVVPEIEFPPSL------------DLHQEIPQQEDQKKEVPKRILDQNFGEPHI 408
P K VPE + PP + + H +I Q+E V K+ P
Sbjct: 9611 EPKKP---VPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEE 9667
Query: 409 PSRLPP--LPLHIRIQQALTSPLPMTPILEGSHRAHSLLFE----NSDSFSEDSSTLGRT 462
P R P L ++ ++ P +T + + + E E + +
Sbjct: 9668 PKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKE 9727
Query: 463 RSLPITIEMLKVPDDEE-EEEQTCPSTFSEEMTPTSVIPKLP-----QCLREEEEKESDS 516
R+ + E + V +EE EE + EE PT + + R EE +E +
Sbjct: 9728 RAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYIT 9787
Query: 517 DSEGPIQYRDEEDED-ESYQSALANKVKRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWN 575
+ E PI + +E + A KV +K K+ P L P K EE
Sbjct: 9788 EPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKV---PVPIPKKLKPPPPKVPEEPK 9844
Query: 576 EI-RHQIGNTLIRRLSQRPTPEELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVA 634
++ +I ++ +R ++ T E + ++PK EK + R+ + P V
Sbjct: 9845 KVFEEKIRISITKREKEQVT--EPAAKVPMKPKRVV--AEEKVPVPRKEVAPPVRVPEVP 9900
Query: 635 ELLARKILRFNEYVEVTDAQDY 656
+ L + + F E V VT ++Y
Sbjct: 9901 KELEPEEVAFEEEV-VTHVEEY 9921
Score = 32.3 bits (72), Expect = 1.5
Identities = 69/361 (19%), Positives = 132/361 (36%), Gaps = 55/361 (15%)
Query: 352 PPE-PPRTPPFPAKTFQVVPEIEFPPSL--DLHQEIPQQEDQKKEVPKRILDQNFGEPHI 408
PP+ P P P + VP E PP + + +P E+ KK PKRI
Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEE-KKPPPKRI---------- 8982
Query: 409 PSRLPPLPLHIRIQQALTSPLPMTP---ILEGSHRAHSLLFENSDSFSEDSSTLGRTRSL 465
+ + ++ + P MTP I++ +L+ + + SS + +
Sbjct: 8983 --EVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIM 9040
Query: 466 PITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYR 525
IT + + ++E+E + I + E E + E P Y
Sbjct: 9041 TIT----RKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQP--YY 9094
Query: 526 DEEDEDESYQSALANKVKRKDTLAMKLNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTL 585
+E DED Y+ KV+ K + H E + + +E ++E
Sbjct: 9095 EEPDED--YEEI---KVEAKKEV-----HEEWEEDFEEGQEYYEREEGYDE--------- 9135
Query: 586 IRRLSQRPTPEELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPT------VAELLAR 639
+ E ++R ++Q + E ++ +R++ ++ K + P V E + +
Sbjct: 9136 ----GEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEK 9191
Query: 640 KILRFNEY-VEVTDAQDYDRRADKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTR 698
R E V+VT + ++ TP + I ++ + +M + EE F
Sbjct: 9192 TSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFAS 9251
Query: 699 Y 699
+
Sbjct: 9252 H 9252
Score = 32.0 bits (71), Expect = 2.0
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 13/96 (13%)
Query: 253 VPAKQPPIPPPKPAHRNSNP----VIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTL 308
+P K PP PPKP R+ P A+L++ + + PSP + PS V ++
Sbjct: 249 LPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPS-PVRSV 307
Query: 309 ESAAAITTKTPSDER--------EKSTCSMGSELLP 336
AA I+T R + ST + G E+ P
Sbjct: 308 SPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPP 343
Score = 29.6 bits (65), Expect = 10.0
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 14/115 (12%)
Query: 63 EVLERKISMRKPREELVKRGVLLEDPEQGGE----DPGKPSDAMLKNGHTTPIGNARSSS 118
EVL +++ +P EE + + E+P E P + + + K + A +
Sbjct: 10231 EVLPVEVT-EEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKK-----AVPEAPTPV 10284
Query: 119 PVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKR 173
P +VE P +++ K IPEE + + + P ++ VP+ VP+ +L PK+
Sbjct: 10285 PKKVEAPPAKVS---KKIPEEKVPVPVQKKEAPP-AKVPEVPKKVPEKKVLVPKK 10335
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 63.9 bits (154), Expect = 5e-10
Identities = 114/469 (24%), Positives = 159/469 (33%), Gaps = 109/469 (23%)
Query: 88 PEQGGEDPGKPSDAML-------KNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEED 140
P + G+ P DA+ K GH T + + P+Q E +P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSM-QPKEPGPLQCEAKP-------------- 418
Query: 141 LKKRLGSTGSQPNSEAESVPENVPKPPLLPPKR-PLSSSHEASEGQAKDATSSGGTARFI 199
LG G Q + E+ P N P L PP+ PLS E S S
Sbjct: 419 ----LGKAGVQLEPQLEA-PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASR------- 466
Query: 200 ISTSITTAPAATTAATSLAKTVNLS-------VTP-------SPAPRTLPAAPASTNTTA 245
+ P A+ L + ++LS ++P SP P + P +P + +
Sbjct: 467 -----LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS 521
Query: 246 TPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSV 305
P + PA + P+ PP A S P + SP PP +P++
Sbjct: 522 PPEESPPSPALETPLSPPPEASPLSPPF---------------EESPLSPPPEELPTSPP 566
Query: 306 PTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRT-PPFPAK 364
P E S S E PM P SP P PPE R PPF
Sbjct: 567 P-----------------EASRLSPPPEESPMSPPPEESPMSP---PPEASRLFPPFEES 606
Query: 365 TFQVVPEIEFP--PSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQ 422
PE E P P + + P ED P + P SRL PLP+ R+
Sbjct: 607 PLSPPPE-ESPLSPPPEASRLSPPPEDSPMSPPPE--ESPMSPPPEVSRLSPLPVVSRLS 663
Query: 423 QALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTL----GRTRSLPITIEMLKVPDDE 478
P++P E S + EDS T S P ++ +P +E
Sbjct: 664 PP-PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722
Query: 479 E------EEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKESDSDSEGP 521
EE Q CP + ++P P+ P EE +E P
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPR---PEEPHLSPRPEEPHLSPQAEEP 768
Score = 43.9 bits (102), Expect = 5e-04
Identities = 104/452 (23%), Positives = 155/452 (34%), Gaps = 63/452 (13%)
Query: 86 EDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRL 145
E+P + G + H +P SPV EEP L E L +
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP--EEPC----LSPQPEESHLSPQS 837
Query: 146 GSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSIT 205
P E + + KPPL P RP E + A + F +
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSP--RPEKPPEEPGQCPAPEELPL-----FPPPGEPS 890
Query: 206 TAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKP 265
+P A S LS P P LP +P+ PSL+ P PP P P P
Sbjct: 891 LSPLLGEPALSEPGEPPLS----PLPEELPLSPSGE-----PSLS---PQLMPPDPLPPP 938
Query: 266 AHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREK 325
+P+I + S P L G S P AA I +TP +
Sbjct: 939 L----SPIITAAAPPALS------PLGELEYPFGAKGDSDPESPLAAPIL-ETPISPPPE 987
Query: 326 STCSMGSELLPMISPRSPSPPL----PTHIPPEPPRTPPFPAKTF---QVVPEIEFPPSL 378
+ C+ + PMI P SP P+ P + P PP+ P + P PP+L
Sbjct: 988 ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL 1047
Query: 379 DLHQEIPQQEDQK------KEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMT 432
L P K + + + EP P+ ++ + TSPLP +
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPA----------LEPSATSPLP-S 1096
Query: 433 PILEGSHRAHS--LLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFS 490
P+ + S A S ++ ED++ L + E + P E + P
Sbjct: 1097 PMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLD 1156
Query: 491 -EEMTPTSVIPKLPQCLREEEEKESDSDSEGP 521
EE+ P + + P+C + + + E P
Sbjct: 1157 PEELAPVTPMEVYPECKQTAGQGSPCEEQEEP 1188
Score = 39.7 bits (91), Expect = 0.010
Identities = 48/208 (23%), Positives = 71/208 (34%), Gaps = 22/208 (10%)
Query: 225 VTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSG 284
++P L P A P H+ P + P P+P + +P E
Sbjct: 761 LSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEE-------- 812
Query: 285 TLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSEL-LPMISPRSP 343
P L P P S ES + ++ P + EL P +SPR
Sbjct: 813 -------PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
Query: 344 SPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNF 403
PP P P P FP + + P+L E P +P+ +
Sbjct: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP-----LSPLPEELPLSPS 920
Query: 404 GEPHI-PSRLPPLPLHIRIQQALTSPLP 430
GEP + P +PP PL + +T+ P
Sbjct: 921 GEPSLSPQLMPPDPLPPPLSPIITAAAP 948
Score = 33.1 bits (74), Expect = 0.90
Identities = 65/274 (23%), Positives = 93/274 (33%), Gaps = 53/274 (19%)
Query: 107 HTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKP 166
HTTP G R + + P+ LK R S + E+ V
Sbjct: 2227 HTTPPGTPRH----------------QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASE 2270
Query: 167 PLLPPKRPLSSSHEASEGQAKDATSSGGT-----ARFIISTSITT--------------A 207
PLL P P S +A E + ++ +S + F+ S S T A
Sbjct: 2271 PLLSPP-PFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKA 2329
Query: 208 PAATTAATSLAKTVNLSVTPS---PAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPK 264
P A+ ++ L + P PA P+ P+ + S T P QPP+ P
Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD--PYAQPPLTP-- 2385
Query: 265 PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLES---AAAITTKTPSD 321
P E A+ +L S P +P S+S L +A +P
Sbjct: 2386 ----RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441
Query: 322 EREKSTCSMGSELLPMISPRSPSPPLPTHIPPEP 355
R +S P P+S P P H PP P
Sbjct: 2442 PRFQSPDPYSR---PPSRPQSRDPFAPLHKPPRP 2472
Score = 32.3 bits (72), Expect = 1.5
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 11/106 (10%)
Query: 262 PPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSD 321
PP+P S P A + I S T + S P+ SVP +S + K P
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
Query: 322 EREKSTCSMGSELLPMISP--RSPSPPLPTHIPPEPPRTPPFPAKT 365
+ +P P +P+ PL P PP PP+P+ T
Sbjct: 2167 VPAQ---------VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT 2203
Score = 32.3 bits (72), Expect = 1.5
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 336 PMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVP 395
P++ P P+PP + P EP R P+ + Q+ E + PP+ H P+ + E P
Sbjct: 4300 PVLGPVHPTPPPSS--PQEPKRPSQLPSPSSQLPTEAQLPPT---HPGTPKPQGPTLEPP 4354
Score = 30.4 bits (67), Expect = 5.8
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 227 PSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKP 265
PSP P L +PAS T L P +PP+P P P
Sbjct: 4914 PSPPPSPLAPSPASPPTEPLVELP-TEPLAEPPVPSPLP 4951
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 61.2 bits (147), Expect = 3e-09
Identities = 92/380 (24%), Positives = 135/380 (35%), Gaps = 81/380 (21%)
Query: 71 MRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLA 130
+R EE V RG E P++ G D +S P P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRD---------------TSGPTPGTPSPAMAR 178
Query: 131 SLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDAT 190
R A E L + P P+PP P++ +SS+ E S + A
Sbjct: 179 RSRAAGTEVGLPR--------------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224
Query: 191 ----SSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTAT 246
S+GG + S S++++ T +S A++ P+ R P APA +
Sbjct: 225 RRRPSAGGGLQRPASRSLSSS---ATPLSSPARS-------GPSARGTPRAPAHPSQPKP 274
Query: 247 PSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVP 306
L + P P + PP+ +++ P + LS S P P + S + P
Sbjct: 275 KGLQALRP---PQVTPPR---KDAAPALGPLS---------SSPLATPSPSAALQSQAPP 319
Query: 307 TLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTF 366
TL + TP TC + + L ++P SPS P P PP TPP A T
Sbjct: 320 TLPA-------TPHSS--SLTCQLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 367 QVVPEIE-------FPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHI-----PSRLPP 414
P ++ PP L PQ P + P + PS P
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Query: 415 LPLHIRIQQALTSPLPMTPI 434
L + + QA SP P P+
Sbjct: 429 NALAVHLLQAPFSPPPSPPV 448
Score = 52.4 bits (124), Expect = 1e-06
Identities = 83/336 (24%), Positives = 117/336 (34%), Gaps = 45/336 (13%)
Query: 98 PSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEA- 156
PS A+ T SSS P+ LA + P + L S + P S+A
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS--LQTLPSPPATPPSQAT 366
Query: 157 --------ESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAP 208
++ +P PPL P P + A A S A +S T +P
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-PASPPLSPLATPSP 425
Query: 209 AATTAATSLAKTVNLSVTPSPA-------PRTLPAAPASTNTTATPSLTHMVPAKQPPIP 261
A A S PSP P + P +P++T + P P + PP P
Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485
Query: 262 PPKPAHRNSNPVIAELSQAINSGTL-LSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPS 320
P P S + + + L L+KP P P P+ + P L++ + P
Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-----PALATPPLQALPSPPASFPG 540
Query: 321 DEREKSTCSMGSELLPMISPRSPSPPLP-THIPPEPPRTPP-FPAKTFQVVPEIEFPPSL 378
+P SPS LP + + PP+ PP A QV P P+L
Sbjct: 541 Q-----------------APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583
Query: 379 DLHQEIPQQ-EDQKKEVPKRILDQNFGEPHIPSRLP 413
+ P D P+ L G P PSR P
Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619
Score = 48.9 bits (115), Expect = 2e-05
Identities = 78/284 (27%), Positives = 101/284 (35%), Gaps = 47/284 (16%)
Query: 116 SSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKP----PLL-- 169
+S PV P A A P L+ S P S + + P P P PL
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 170 --PPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTA--ATSLAKTVNLSV 225
PP+ P + + + S G A F S S+ +P AT A + L V
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573
Query: 226 TPSP-------APRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELS 278
PSP APR P P + + P LT + PP P P+ S P +A
Sbjct: 574 PPSPPASPTLQAPRR-PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG-- 630
Query: 279 QAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMI 338
+S + S P RG S E AA +P + E + C P
Sbjct: 631 ---HSSSATSTPE----ELRGYDSGP----EGGAA---ASPPPDAELAACH------PAA 670
Query: 339 SPRSPSPPL-----PTHIPPEPPRTPPFPAKTFQVVPEIEFPPS 377
R P+PPL P P PP T P A + E E P S
Sbjct: 671 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 714
>gi|15529996 son of sevenless homolog 1 [Homo sapiens]
Length = 1333
Score = 60.8 bits (146), Expect = 4e-09
Identities = 73/287 (25%), Positives = 119/287 (41%), Gaps = 44/287 (15%)
Query: 119 PVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRP-LSS 177
P +++EP +++ R IPE + + ST S PNS P+ PL PP SS
Sbjct: 1053 PTPLQQEPRKISYSR--IPESETE----STASAPNS---------PRTPLTPPPASGASS 1097
Query: 178 SHEASEGQAKDATSSGGTARFIISTSITTAPAATTAA-TSLAKTVNLSVTPSPAPRTLPA 236
+ + D +S ++ + +T +A+ +S++ T P P P
Sbjct: 1098 TTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRR 1157
Query: 237 APASTNTTATPSLTHMVPAKQPP-IPPPKPAHRNSNPVIAELSQAINSGTLLSKP--SPP 293
P S ++PS PP IPP +P + +P +I+ T +S P SPP
Sbjct: 1158 RPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSP-----RYSISDRTSISDPPESPP 1212
Query: 294 LPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPP 353
L P R P + S++ + + P ++ S+ P SPSP P
Sbjct: 1213 LLPPR--EPVRTPDVFSSSPLHLQPPPLGKK-------SDHGNAFFPNSPSP-----FTP 1258
Query: 354 EPPRTPPFPAKTFQVVPEIEFPPSLDLHQ----EIPQQEDQKKEVPK 396
PP+TP P T + +P +DLH +P ++ + +PK
Sbjct: 1259 PPPQTPS-PHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPK 1304
Score = 33.1 bits (74), Expect = 0.90
Identities = 53/243 (21%), Positives = 86/243 (35%), Gaps = 43/243 (17%)
Query: 85 LEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQV------EEEPVRLASLRKAIPE 138
L P G ++ + H++P ++ + +QV V SL K E
Sbjct: 1087 LTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDE 1146
Query: 139 EDLKKRLGSTGSQPNSEAESVPENV-----PKPPLLPPKRPLSSSHEASEGQAKDATSSG 193
+ + ++ AES P + PP +PP++P TS
Sbjct: 1147 VPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQP---------------TSKA 1191
Query: 194 GTARFIIS--TSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTH 251
+ R+ IS TSI+ P + + V S +P L P + +
Sbjct: 1192 YSPRYSISDRTSISDPPESPPLLPP-REPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFP 1250
Query: 252 MVPAKQPPIPPPKPA------HRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSV 305
P+ P PP P+ H S P+ E+ L S PP+PP++ S +
Sbjct: 1251 NSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVD-------LHSIAGPPVPPRQS-TSQHI 1302
Query: 306 PTL 308
P L
Sbjct: 1303 PKL 1305
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/389 (24%), Positives = 136/389 (34%), Gaps = 60/389 (15%)
Query: 150 SQPNSEAESVPENVPKPPLLPPKRPLSSS-HEASEGQAKDATSSGGTARFIISTSITTAP 208
++P +AE+ + P L PK P ++ E + K+ T + T + +T AP
Sbjct: 288 AKPTPKAETTTKG---PALTTPKEPTPTTPKEPASTTPKEPTPT--TIKSAPTTPKEPAP 342
Query: 209 AATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTA-TPSLTHMVPA--KQP-PIPPPK 264
T +A + K + T PAP T P PA T T P+ T P K+P P P K
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTT-PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 265 PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDERE 324
PA P+ P P P PT A TTK P+
Sbjct: 402 PA-----------------------PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
Query: 325 KSTCSMGSELLPMISPRSPSP-----PLPTHIPPEPPRTPPFPA-KTFQVVPEIEFPPSL 378
K + +P+ P+P P PT P TP PA T + P P+
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA- 497
Query: 379 DLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALT--SPLPMTPILE 436
P PK EP + P P + T P P TP
Sbjct: 498 ------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP--- 548
Query: 437 GSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPS----TFSEE 492
A + + + + ++ + + P T + L P E+ T P T EE
Sbjct: 549 -KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPAPTTPEE 606
Query: 493 MTPTSVIPKLPQCLREEEEKESDSDSEGP 521
+ PT+ P+ P EE + + P
Sbjct: 607 LAPTT--PEEPTPTTPEEPAPTTPKAAAP 633
Score = 60.1 bits (144), Expect = 7e-09
Identities = 118/493 (23%), Positives = 169/493 (34%), Gaps = 69/493 (13%)
Query: 23 EAGDTTP--PTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV- 79
E TTP PT K +P K+ + KE + +K + P+E
Sbjct: 409 EPAPTTPKEPTPTTPK--------EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460
Query: 80 --KRGVLLEDPEQGGEDPGKPSDAMLKNGHTT---PIGNARSSSPVQVEE-EPVRLASLR 133
K E P +P+ K+ TT P S+P +E P
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 520
Query: 134 KAIPEEDL----KKRLGSTGSQP--NSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAK 187
P+E KK +T +P + E P KP PK P ++ + +
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 188 DATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAP--ASTNTTA 245
+ + +T AP T LA T TP+ P P A+ NT
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 637
Query: 246 TPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSV 305
P+ T P + P P +PA A + + T L +P+P P K
Sbjct: 638 EPAPT--TPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKK-------- 686
Query: 306 PTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEP-PRTPPFPAK 364
P + A TTK P+ +TC +P +P PT P EP P TP PA
Sbjct: 687 PAPKELAPTTTKEPT----STTCDKP-------APTTPKGTAPT-TPKEPAPTTPKEPAP 734
Query: 365 TFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQA 424
T P+ P +L + P KK PK + P + P P +
Sbjct: 735 T---TPKGTAPTTL----KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 787
Query: 425 LT--SPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE 482
T P P TP + E + + ST T+ P TI K PD+ E
Sbjct: 788 TTPKEPAPTTP-----KKPAPTTPETPPPTTSEVSTPTTTKE-PTTIH--KSPDESTPEL 839
Query: 483 QTCPSTFSEEMTP 495
P+ + E +P
Sbjct: 840 SAEPTPKALENSP 852
Score = 55.5 bits (132), Expect = 2e-07
Identities = 85/386 (22%), Positives = 136/386 (35%), Gaps = 58/386 (15%)
Query: 27 TTPPTKRKSKF-SGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGVLL 85
T+PP+ +K+ SG + K R K +K K+T +V+E EE+ + +
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNK-KKTKKVIES--------EEITEEHSVS 120
Query: 86 EDPEQGGEDPGKPSDAMLKN--GHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKK 143
E+ E S + ++ N ++V++ + + +K P+ +
Sbjct: 121 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK-KNRTKKKPTPKPPVVD 179
Query: 144 RLGS--------------TGSQPNSEAESVPENVPKP----PLLPPKRPLSSS-----HE 180
GS + +Q N + S KP P LPP S ++
Sbjct: 180 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 239
Query: 181 ASEGQAKDATSSGGTARFIISTSITTAPAAT----TAATSLAKTVNLSVTPSPAPRTLPA 236
+ + K+ T++ T+A T+A LA T + P+P T
Sbjct: 240 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 299
Query: 237 APASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLP- 295
PA T T PA P P P S P + + + + P P P
Sbjct: 300 GPALTTPKEPTPTTPKEPASTTP-KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 358
Query: 296 ---------PKRGIPSTS---VPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSP 343
PK P+T+ PT +A T K P+ K + +P+ P
Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418
Query: 344 SPPLPTHIPP---EP-PRTPPFPAKT 365
+P P P EP P TP PA T
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPT 444
Score = 39.3 bits (90), Expect = 0.013
Identities = 69/343 (20%), Positives = 109/343 (31%), Gaps = 31/343 (9%)
Query: 95 PGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNS 154
P KP+ L T + S P + + ++ P K + + P +
Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 812
Query: 155 EAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI--ISTSITTAPAATT 212
+E K P K P S+ E S A + + T T P TT
Sbjct: 813 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 872
Query: 213 AATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPS--------------LTHMVPAKQP 258
A +L T P T AAP T TAT + +T
Sbjct: 873 TAKDKTTERDLRTT----PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 928
Query: 259 PIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKT 318
P P + + I + +++KP PK T A +
Sbjct: 929 PFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK------DRATNSKATTPKPQK 982
Query: 319 PSDEREKSTCSMGSELLPMI-SPR-SPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPP 376
P+ +K T + + +P + P+ +P+P T PE T Q P
Sbjct: 983 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 1042
Query: 377 SLDLHQEIPQQED---QKKEVPKRILDQNFGEPHIPSRLPPLP 416
+ L + P+ ED + E P +L + P + + LP
Sbjct: 1043 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 1085
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/389 (24%), Positives = 136/389 (34%), Gaps = 60/389 (15%)
Query: 150 SQPNSEAESVPENVPKPPLLPPKRPLSSS-HEASEGQAKDATSSGGTARFIISTSITTAP 208
++P +AE+ + P L PK P ++ E + K+ T + T + +T AP
Sbjct: 329 AKPTPKAETTTKG---PALTTPKEPTPTTPKEPASTTPKEPTPT--TIKSAPTTPKEPAP 383
Query: 209 AATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTA-TPSLTHMVPA--KQP-PIPPPK 264
T +A + K + T PAP T P PA T T P+ T P K+P P P K
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTT-PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 265 PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDERE 324
PA P+ P P P PT A TTK P+
Sbjct: 443 PA-----------------------PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
Query: 325 KSTCSMGSELLPMISPRSPSP-----PLPTHIPPEPPRTPPFPA-KTFQVVPEIEFPPSL 378
K + +P+ P+P P PT P TP PA T + P P+
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA- 538
Query: 379 DLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALT--SPLPMTPILE 436
P PK EP + P P + T P P TP
Sbjct: 539 ------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP--- 589
Query: 437 GSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPS----TFSEE 492
A + + + + ++ + + P T + L P E+ T P T EE
Sbjct: 590 -KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPAPTTPEE 647
Query: 493 MTPTSVIPKLPQCLREEEEKESDSDSEGP 521
+ PT+ P+ P EE + + P
Sbjct: 648 LAPTT--PEEPTPTTPEEPAPTTPKAAAP 674
Score = 60.1 bits (144), Expect = 7e-09
Identities = 118/493 (23%), Positives = 169/493 (34%), Gaps = 69/493 (13%)
Query: 23 EAGDTTP--PTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV- 79
E TTP PT K +P K+ + KE + +K + P+E
Sbjct: 450 EPAPTTPKEPTPTTPK--------EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501
Query: 80 --KRGVLLEDPEQGGEDPGKPSDAMLKNGHTT---PIGNARSSSPVQVEE-EPVRLASLR 133
K E P +P+ K+ TT P S+P +E P
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 561
Query: 134 KAIPEEDL----KKRLGSTGSQP--NSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAK 187
P+E KK +T +P + E P KP PK P ++ + +
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 188 DATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAP--ASTNTTA 245
+ + +T AP T LA T TP+ P P A+ NT
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 678
Query: 246 TPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSV 305
P+ T P + P P +PA A + + T L +P+P P K
Sbjct: 679 EPAPT--TPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKK-------- 727
Query: 306 PTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEP-PRTPPFPAK 364
P + A TTK P+ +TC +P +P PT P EP P TP PA
Sbjct: 728 PAPKELAPTTTKEPT----STTCDKP-------APTTPKGTAPT-TPKEPAPTTPKEPAP 775
Query: 365 TFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQA 424
T P+ P +L + P KK PK + P + P P +
Sbjct: 776 T---TPKGTAPTTL----KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 828
Query: 425 LT--SPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE 482
T P P TP + E + + ST T+ P TI K PD+ E
Sbjct: 829 TTPKEPAPTTP-----KKPAPTTPETPPPTTSEVSTPTTTKE-PTTIH--KSPDESTPEL 880
Query: 483 QTCPSTFSEEMTP 495
P+ + E +P
Sbjct: 881 SAEPTPKALENSP 893
Score = 55.5 bits (132), Expect = 2e-07
Identities = 85/386 (22%), Positives = 136/386 (35%), Gaps = 58/386 (15%)
Query: 27 TTPPTKRKSKF-SGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGVLL 85
T+PP+ +K+ SG + K R K +K K+T +V+E EE+ + +
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNK-KKTKKVIES--------EEITEEHSVS 161
Query: 86 EDPEQGGEDPGKPSDAMLKN--GHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKK 143
E+ E S + ++ N ++V++ + + +K P+ +
Sbjct: 162 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK-KNRTKKKPTPKPPVVD 220
Query: 144 RLGS--------------TGSQPNSEAESVPENVPKP----PLLPPKRPLSSS-----HE 180
GS + +Q N + S KP P LPP S ++
Sbjct: 221 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 280
Query: 181 ASEGQAKDATSSGGTARFIISTSITTAPAAT----TAATSLAKTVNLSVTPSPAPRTLPA 236
+ + K+ T++ T+A T+A LA T + P+P T
Sbjct: 281 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 340
Query: 237 APASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLP- 295
PA T T PA P P P S P + + + + P P P
Sbjct: 341 GPALTTPKEPTPTTPKEPASTTP-KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 399
Query: 296 ---------PKRGIPSTS---VPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSP 343
PK P+T+ PT +A T K P+ K + +P+ P
Sbjct: 400 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459
Query: 344 SPPLPTHIPP---EP-PRTPPFPAKT 365
+P P P EP P TP PA T
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPT 485
Score = 39.3 bits (90), Expect = 0.013
Identities = 69/343 (20%), Positives = 109/343 (31%), Gaps = 31/343 (9%)
Query: 95 PGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNS 154
P KP+ L T + S P + + ++ P K + + P +
Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 853
Query: 155 EAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI--ISTSITTAPAATT 212
+E K P K P S+ E S A + + T T P TT
Sbjct: 854 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 913
Query: 213 AATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPS--------------LTHMVPAKQP 258
A +L T P T AAP T TAT + +T
Sbjct: 914 TAKDKTTERDLRTT----PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 969
Query: 259 PIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKT 318
P P + + I + +++KP PK T A +
Sbjct: 970 PFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPK------DRATNSKATTPKPQK 1023
Query: 319 PSDEREKSTCSMGSELLPMI-SPR-SPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPP 376
P+ +K T + + +P + P+ +P+P T PE T Q P
Sbjct: 1024 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 1083
Query: 377 SLDLHQEIPQQED---QKKEVPKRILDQNFGEPHIPSRLPPLP 416
+ L + P+ ED + E P +L + P + + LP
Sbjct: 1084 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 1126
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 60.8 bits (146), Expect = 4e-09
Identities = 82/324 (25%), Positives = 119/324 (36%), Gaps = 39/324 (12%)
Query: 106 GHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVP--ENV 163
G TPIGN SSPV PV + L PE L + GS S + + + P +
Sbjct: 816 GPDTPIGNL--SSPVS----PVEASFL----PENSLSFQ-GSKDSPATTHSPTPPSPKGA 864
Query: 164 PKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNL 223
P P + P P + E + + + APA + ++S K
Sbjct: 865 PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA--- 921
Query: 224 SVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPK--PAHRNSNPVIAELSQAI 281
+PAP+ +PA+P+ P+ T P P P PK P + P + A
Sbjct: 922 --RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979
Query: 282 NSGTLLSKPSPPL---PPKRGIPSTSVPT-LESAAAITTKTPSDEREKSTCSMGSELLPM 337
S P+PP P +G P+T P + A+T +P + G+ P
Sbjct: 980 PSPK--GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 338 ISPRSP-----SPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKK 392
+P SP + PLP P P T P P K P ++ P+ +
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSP-KGGPATPSLKGAPTPPAATPPSPKGGPAT 1096
Query: 393 EVPKRILDQNFGEPHIPSRLPPLP 416
PK G P P+ PP P
Sbjct: 1097 PSPK-------GAPMPPAATPPSP 1113
Score = 59.3 bits (142), Expect = 1e-08
Identities = 69/287 (24%), Positives = 107/287 (37%), Gaps = 39/287 (13%)
Query: 80 KRGVLLEDPEQGGEDPGKPSDAML--KNGHTTPIGNARSSSPVQVEEEP--VRLASLRKA 135
KRG + P+ DP P+ L K TP+ +++P + + P V SL+KA
Sbjct: 1390 KRGPAIPSPKG---DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 136 IPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGT 195
K + S+ + +V PK P P + +++S + A A T
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEP--PAPKQVATSSSPKKAPATPAPMGAPT 1504
Query: 196 ARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPA 255
+I +S PA T ++ ++ T + + PA A P++T P
Sbjct: 1505 LPAVIPSSPKEVPA-----TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559
Query: 256 KQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPP---LPPKRGIPSTSVPTLESAA 312
K P IP PK A + A A+ T PSP +PP + S S +
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP--AVTSPSPKEAPTPP 1617
Query: 313 AITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTP 359
A+T +P + P+ P P P PP TP
Sbjct: 1618 AVTPPSPE--------------------KGPATPAPKGTPTSPPVTP 1644
Score = 55.1 bits (131), Expect = 2e-07
Identities = 85/366 (23%), Positives = 122/366 (33%), Gaps = 50/366 (13%)
Query: 70 SMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRL 129
S +K R +G+ +G P + K G TP + P P
Sbjct: 917 SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK-- 974
Query: 130 ASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDA 189
P+ + S A P+ P PP + P P S A+ K A
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP--AATPFPKGA 1032
Query: 190 TSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPS---PAPRTLPAAPASTNTTAT 246
++ + +P + AAT L K TP+ P+P+ PA P+
Sbjct: 1033 STP--------PAATPPSPKGSPAATPLPK--GAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 247 PSLTHMVPAKQPPIPPPK-----PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI- 300
P+ T P P P PK PA +P L+ + G + + P PK G+
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPK-GGLATPPHKGAPTTPAATPPSPKGGLA 1141
Query: 301 --PSTSVPTLESAAAITTK----TPSDEREKSTCSMGSELLPMISPRSP----SPPLPTH 350
P PT +A + K TP + G+ P +P SP + P P
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPK--------GAPTTPAATPPSPKGGLATPSPKG 1193
Query: 351 IPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPS 410
P P TPP P K P + P+ + PK G P P+
Sbjct: 1194 APTTPAATPPSP-KGGLATPSPKGAPTTPAATPPSPKGGLATPSPK-------GAPTTPA 1245
Query: 411 RLPPLP 416
PP P
Sbjct: 1246 ATPPSP 1251
Score = 46.6 bits (109), Expect = 8e-05
Identities = 80/353 (22%), Positives = 109/353 (30%), Gaps = 31/353 (8%)
Query: 81 RGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEED 140
+G L P +G + K G TP ++P P L P+
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK--GGLATPSPKGA 1194
Query: 141 LKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLS-----SSHEASEGQAKDATSSGGT 195
+ S A P+ P P P P S A A S G
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254
Query: 196 ARFIISTSITTAPAATTA------ATSLAKTV-NLSVTPSPAPRTLPAAPASTNTTATPS 248
T PAAT AT K N +V P+P+ PA P+
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314
Query: 249 LTHMVPAKQPPIPPPK--PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVP 306
T P P PPPK P P + + + + T SK P P + P+
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374
Query: 307 TLESAAAITTKTPSDEREKSTCS-MGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKT 365
T PS +R + S G P + P SP T + E TP
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP----SK 1430
Query: 366 FQVVPEIEFPPSLDLHQEIPQQEDQKKEVPK--RILDQNFGEPHIPSRLPPLP 416
+ P P SL ++ PK + G+P +P+ PP P
Sbjct: 1431 GDLTPPAVTPVSL--------KKAPATSAPKGGPATPSSKGDPTLPAVTPPSP 1475
Score = 45.8 bits (107), Expect = 1e-04
Identities = 103/521 (19%), Positives = 177/521 (33%), Gaps = 67/521 (12%)
Query: 118 SPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSS 177
+P+ P + S K +P +R + ++ PK L+PP + S
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 178 SHEASE-GQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPA 236
+ K+A ++ + ++T P+ A S + + SP+P+ P
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVT--PSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 237 APASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPP 296
PA T + P P PP P+ +P + S G + + S LP
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT-SPASVTCKMGATVPQASKGLPA 1674
Query: 297 KRGIPSTS----VPTLESAAAITTKTPSDEREKSTCSMGSELLP----------MISPRS 342
K+G + P ES IT T + K + + + P +S +
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734
Query: 343 PSPPLPTH--------------------IPPEPPRTPPFPAKTFQ-VVPEIEF------- 374
P+P LP PPE + P A F+ V+P+ E
Sbjct: 1735 PAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP 1794
Query: 375 --PPSLDL-HQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPM 431
P SL L +P +++ +P P + P PL + L +P
Sbjct: 1795 SPPVSLPLAPSPVPTLPPKQQFLP--------SSPGLVLESPSKPLAPADEDELLPLIPP 1846
Query: 432 TPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSE 491
PI G S+L S + P+T + K E + +++ P E
Sbjct: 1847 EPI-SGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVT-KNNKGSGTESDSDESVPEL--E 1902
Query: 492 EMTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDESYQSALANKVKRKDTLAMK 551
E T + Q E E P+ + ++ + A++ R+ T +
Sbjct: 1903 EQDSTQATTQQAQLAAAAEIDEE------PVSKAKQSRSEKKARKAMSKLGLRQVTGVTR 1956
Query: 552 LNHRPSEPELNLNSWPCKSKEEWNEIRHQIGNTLIRRLSQR 592
+ R S+ L + + P K ++ G I LSQ+
Sbjct: 1957 VTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQ 1997
Score = 45.1 bits (105), Expect = 2e-04
Identities = 75/301 (24%), Positives = 105/301 (34%), Gaps = 71/301 (23%)
Query: 156 AESVPENVPKPPLLPPKRPLSS------SHEAS--------------EGQAKDATSSGGT 195
A +P++VP P L P P + SH ++ + A SS GT
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
Query: 196 ARFI----------ISTSITTAPAATTAATSLAKTVNLSVTPSPAPRT-LPAAPAS-TNT 243
++ +S P +A NLS SP + LP S +
Sbjct: 787 LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846
Query: 244 TATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLP-------P 296
+P+ TH P P PK A P + ++ G L P P P
Sbjct: 847 KDSPATTH-----SPTPPSPKGA-----PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896
Query: 297 KRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPR-SPSPPLPTHIPPEP 355
K G P+T P A ++T+ +P R + G P SP+ +P+PP T PP P
Sbjct: 897 KEG-PATPAPKQAPALSMTSSSPKKAR-ATPAPKGIPASP--SPKGAPTPPAAT--PPSP 950
Query: 356 PRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPL 415
P P+ + P PPS P PK G P P+ PP
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPS--------PK-------GAPTPPAATPPS 995
Query: 416 P 416
P
Sbjct: 996 P 996
Score = 35.4 bits (80), Expect = 0.18
Identities = 62/227 (27%), Positives = 90/227 (39%), Gaps = 23/227 (10%)
Query: 154 SEAESVPENVPKPPLLPP---KRP--LSSSHEASEGQAKDATSSGGTARFIISTSITTAP 208
S E VP V P++ P K P +SS + G ATS + S + ++P
Sbjct: 362 SRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPT--TSLILKSSP 419
Query: 209 AATTAATSLAKTVNLSVTPSPA----PRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPK 264
AT +A+ SV +P P T+ AAP +T AT M I P
Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTS 479
Query: 265 PAHRNSNPVIAELSQAINSGTLLSKPSPPLPPK---RGIPST---SVPT---LESAAAIT 315
PA PV + + TL SPPLP + +PS+ PT L++ A
Sbjct: 480 PAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASL 539
Query: 316 TKTP-SDEREKSTCSMGSELLPMI--SPRSPSPPLPTHIPPEPPRTP 359
P S + T +LP++ +P++ T PE P +P
Sbjct: 540 EGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSP 586
Score = 34.3 bits (77), Expect = 0.40
Identities = 39/146 (26%), Positives = 55/146 (37%), Gaps = 29/146 (19%)
Query: 250 THMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLE 309
T VPA + +P P+ + + +S A++ L +P P LPP P
Sbjct: 6 TETVPATEQELPQPQ-----AETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL-- 58
Query: 310 SAAAITTKTPSDEREKST--------CSMGSELLPMISPRSPSPPLPTHIPP--EPPRTP 359
SAA + PS ST S G+ L P +P PT +P PP +P
Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQSSSGTAL-----PLGTAPEAPTFLPNLIGPPISP 113
Query: 360 -------PFPAKTFQVVPEIEFPPSL 378
P A T + P P +L
Sbjct: 114 AALALASPMIAPTLKGTPSSSAPLAL 139
Score = 33.1 bits (74), Expect = 0.90
Identities = 57/236 (24%), Positives = 86/236 (36%), Gaps = 39/236 (16%)
Query: 167 PLLPPKRPLS-SSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSV 225
P PP P+S SH A Q SS G+ + + T P+A + T +V+ S
Sbjct: 295 PNTPPDFPISLGSHLAPLHQ-----SSFGSVQLLGQTG----PSALSDPTVKTISVDHSS 345
Query: 226 TPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAEL----SQAI 281
T + P P PS +VPA P P+ I+ + S ++
Sbjct: 346 TGASYPSQRSVIPP------LPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSL 399
Query: 282 NSGT---------LLSKPSP------PLPPKRGIPST-SVPTLESAAAITTKTPSDEREK 325
N T L+ K SP PL + + S + P + + P+ E
Sbjct: 400 NVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEV 459
Query: 326 STC---SMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSL 378
+TC M S + I P SP+ + + P+ P T V P + P L
Sbjct: 460 ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDL 515
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 59.7 bits (143), Expect = 9e-09
Identities = 92/368 (25%), Positives = 128/368 (34%), Gaps = 58/368 (15%)
Query: 84 LLEDPE--QGGEDPG----KPSDAMLKNG--HTTPIGNARSSSPVQVEEEPVRLASLRKA 135
+LE P+ GG G +P + + G P+G A+ S + +++ S R A
Sbjct: 63 ILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVG-AKDGSENLAGKPALQIPSSRAA 121
Query: 136 IPEEDLKKRLGSTGSQPNSEAESVPE--NVPKPPLLPPKRPLSSSHEASEGQAKDATSSG 193
P + G +S S+PE + +P L RP + TSS
Sbjct: 122 APRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRP-------------NTTSST 168
Query: 194 GTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMV 253
G S+S P A + + + + +PA P + P
Sbjct: 169 GMKH---SSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPG-REGP 224
Query: 254 PAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPS-TSVPTLESAA 312
PA P PPP P + + P SG L+ P PP G+P+ S PT ESA
Sbjct: 225 PAPPPVKPPPSPVNIRTGP----------SGQSLAPPPPPYRQPPGVPNGPSSPTNESAP 274
Query: 313 AITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEI 372
+ + S R+ G P P S SP L ++ PP P R PP P +
Sbjct: 275 ELPQRHNSLHRKTPGPVRGLAPPP---PTSASPSLLSNRPPPPARDPPSRGAAPPPPPPV 331
Query: 373 EFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMT 432
+ D P E P R P PSR P P P P
Sbjct: 332 IRNGARDAPPPPPPYRMHGSEPPSR-----GKPPPPPSRTPAGP-----------PPPPP 375
Query: 433 PILEGSHR 440
P L HR
Sbjct: 376 PPLRNGHR 383
Score = 35.8 bits (81), Expect = 0.14
Identities = 59/232 (25%), Positives = 76/232 (32%), Gaps = 33/232 (14%)
Query: 95 PGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPV------RLASLRKAIPEEDLKK----- 143
P P N TP+ S +P E+P+ RL R+ P K
Sbjct: 177 PPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSP 236
Query: 144 ---RLGSTGSQ--PNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARF 198
R G +G P P VP P P S+ E + + G R
Sbjct: 237 VNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNE---SAPELPQRHNSLHRKTPGPVRG 293
Query: 199 IISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQP 258
+ P T+A+ SL LS P P R P+ A+ P + P
Sbjct: 294 L------APPPPTSASPSL-----LSNRPPPPARDPPSRGAAP--PPPPPVIRNGARDAP 340
Query: 259 PIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLES 310
P PPP H S P S T P PP PP R S+ T+ S
Sbjct: 341 PPPPPYRMH-GSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRS 391
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 59.3 bits (142), Expect = 1e-08
Identities = 120/523 (22%), Positives = 183/523 (34%), Gaps = 101/523 (19%)
Query: 54 SSDKFKETSEVLERK-ISMRKPREELVKRGVLLEDPEQGGEDP----GKPSDAMLKNGHT 108
SS ET+ + E IS +KP + K V E P E P KP+ + K
Sbjct: 549 SSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIP 608
Query: 109 TPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVP---- 164
+ N S P E+P L + IP E K + S ++E +VP P
Sbjct: 609 SEKPNMPSEKPTIPSEKPTILTE-KPTIPSE--KPTIPSEKPTISTEKPTVPTEEPTTPT 665
Query: 165 -------KPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIIST-SITTAPAATTAATS 216
+ P++P ++P + + S K S T IIST T +P T T
Sbjct: 666 EETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEET---IISTEKPTISPEKPTIPTE 722
Query: 217 LAKTVNLSVTPSPAPRTLPAAPAS-------------TNTTATPSLTH---MVPAKQPPI 260
T SP T P + T T P+++ +P ++P I
Sbjct: 723 KPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTI 782
Query: 261 PPPKPAHRNSNPVIA-ELSQAINSGTLLS--KPSPP------------------------ 293
P KP P I+ E T +S KPS P
Sbjct: 783 PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEK 842
Query: 294 --LPPKRGIPSTSVPTLES---------------AAAITTKTPSDEREKSTCSMGSELLP 336
+P ++ ST PT+ + I T+ P+ E++T S +P
Sbjct: 843 LTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIP 902
Query: 337 ----MISPRSPS-----PPLPTHIPPEPPRTPPFPAKTFQVVPE--IEFPPSLDLHQEIP 385
ISP P+ P +PT P P + + E P L + E P
Sbjct: 903 TEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP 962
Query: 386 QQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLL 445
+K +P L +P IP+ P +P + LT+ P P + A ++
Sbjct: 963 TISTEKPTIPTEKLTIPTEKPTIPTEKPTIP-----TEKLTALRPPHPSPTATGLAALVM 1017
Query: 446 FENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPST 488
++ S S LG T + + E + P + E CP++
Sbjct: 1018 SPHAPSTPMTSVILGTTTTSRSSTE--RCPPNARYESCACPAS 1058
Score = 55.8 bits (133), Expect = 1e-07
Identities = 72/359 (20%), Positives = 132/359 (36%), Gaps = 32/359 (8%)
Query: 163 VPKP-PLLPPKRPLSSSHEASEGQAK-DATSSGGTARFIISTSITTAPAATTAATSL-AK 219
VPK P +P ++P S+ + + K + S T T +T P + ++ ++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645
Query: 220 TVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQ 279
+S P P P TT+ ++P ++P IP KP+ P I+
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEE--PVIPTEKPSIPTEKPSIPTEKPTIS---- 699
Query: 280 AINSGTLLSKPSPPLPPKRGIPSTSVPTLES-AAAITTKTPSDEREKSTCSMGSELLPMI 338
T++S P + P++ T PT+ + + I+ + P+ EK T P I
Sbjct: 700 --MEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEK---PTI 754
Query: 339 SPRSPSPP------------LPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLD--LHQEI 384
SP P+ P +PT P P P P + + E P+ + + E
Sbjct: 755 SPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
Query: 385 PQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSL 444
P +K +P + E I + +P+ + +++ P P + + L
Sbjct: 815 PSIPMEKPTLPTEETTTSVEETTISTEKLTIPME---KPTISTEKPTIPTEKPTISPEKL 871
Query: 445 LFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLP 503
I+ E L +P ++ P+ +E+ T + P +P
Sbjct: 872 TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIP 930
Score = 43.9 bits (102), Expect = 5e-04
Identities = 42/169 (24%), Positives = 63/169 (37%), Gaps = 21/169 (12%)
Query: 269 NSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTS---VPTLESAAAITTKTPSDEREK 325
N+ V+A IN GT K P LPP + ST L I+TK P+ EK
Sbjct: 517 NTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK 576
Query: 326 STCSMGSELLPMISPRSPS---------PPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPP 376
+ + +P P P+ P +P+ P P P P++ ++ E P
Sbjct: 577 PSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIP 636
Query: 377 S---------LDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLP 416
S + E P ++ P + EP IP+ P +P
Sbjct: 637 SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
Score = 37.0 bits (84), Expect = 0.062
Identities = 73/357 (20%), Positives = 122/357 (34%), Gaps = 38/357 (10%)
Query: 6 EEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVL 65
E+ PT +P + + P T + K+ P +K + K T
Sbjct: 736 EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP---TEKPTIPTEKPTIPTE 792
Query: 66 ERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEE 125
+ IS +P + + E P E P P++ + T I + + P+ E+
Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPM---EK 849
Query: 126 PVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPL-----------LPPKRP 174
P +++ + IP E K + +E ++P P P+ +P ++P
Sbjct: 850 PT-ISTEKPTIPTE--KPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP 906
Query: 175 LSSSHEASEGQAKDATSSGGTARFIISTSITTAPAA-TTAATSLAKTVNLSVTPSPAPRT 233
S + + K I T T P TT +T T SP T
Sbjct: 907 TISPEKPTISTEKPT----------IPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
Query: 234 LPAAPA--STNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGT-LLSKP 290
+P ST P+ +P ++P IP KP + T L +
Sbjct: 957 IPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALV 1016
Query: 291 SPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPL 347
P P + S + T ++ + T + P + R +S S SPR PL
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPAS----CKSPRPSCGPL 1069
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 59.3 bits (142), Expect = 1e-08
Identities = 120/523 (22%), Positives = 183/523 (34%), Gaps = 101/523 (19%)
Query: 54 SSDKFKETSEVLERK-ISMRKPREELVKRGVLLEDPEQGGEDP----GKPSDAMLKNGHT 108
SS ET+ + E IS +KP + K V E P E P KP+ + K
Sbjct: 549 SSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIP 608
Query: 109 TPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVP---- 164
+ N S P E+P L + IP E K + S ++E +VP P
Sbjct: 609 SEKPNMPSEKPTIPSEKPTILTE-KPTIPSE--KPTIPSEKPTISTEKPTVPTEEPTTPT 665
Query: 165 -------KPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIIST-SITTAPAATTAATS 216
+ P++P ++P + + S K S T IIST T +P T T
Sbjct: 666 EETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEET---IISTEKPTISPEKPTIPTE 722
Query: 217 LAKTVNLSVTPSPAPRTLPAAPAS-------------TNTTATPSLTH---MVPAKQPPI 260
T SP T P + T T P+++ +P ++P I
Sbjct: 723 KPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTI 782
Query: 261 PPPKPAHRNSNPVIA-ELSQAINSGTLLS--KPSPP------------------------ 293
P KP P I+ E T +S KPS P
Sbjct: 783 PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEK 842
Query: 294 --LPPKRGIPSTSVPTLES---------------AAAITTKTPSDEREKSTCSMGSELLP 336
+P ++ ST PT+ + I T+ P+ E++T S +P
Sbjct: 843 LTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIP 902
Query: 337 ----MISPRSPS-----PPLPTHIPPEPPRTPPFPAKTFQVVPE--IEFPPSLDLHQEIP 385
ISP P+ P +PT P P + + E P L + E P
Sbjct: 903 TEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP 962
Query: 386 QQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLL 445
+K +P L +P IP+ P +P + LT+ P P + A ++
Sbjct: 963 TISTEKPTIPTEKLTIPTEKPTIPTEKPTIP-----TEKLTALRPPHPSPTATGLAALVM 1017
Query: 446 FENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPST 488
++ S S LG T + + E + P + E CP++
Sbjct: 1018 SPHAPSTPMTSVILGTTTTSRSSTE--RCPPNARYESCACPAS 1058
Score = 55.8 bits (133), Expect = 1e-07
Identities = 72/359 (20%), Positives = 132/359 (36%), Gaps = 32/359 (8%)
Query: 163 VPKP-PLLPPKRPLSSSHEASEGQAK-DATSSGGTARFIISTSITTAPAATTAATSL-AK 219
VPK P +P ++P S+ + + K + S T T +T P + ++ ++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645
Query: 220 TVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQ 279
+S P P P TT+ ++P ++P IP KP+ P I+
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEE--PVIPTEKPSIPTEKPSIPTEKPTIS---- 699
Query: 280 AINSGTLLSKPSPPLPPKRGIPSTSVPTLES-AAAITTKTPSDEREKSTCSMGSELLPMI 338
T++S P + P++ T PT+ + + I+ + P+ EK T P I
Sbjct: 700 --MEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEK---PTI 754
Query: 339 SPRSPSPP------------LPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLD--LHQEI 384
SP P+ P +PT P P P P + + E P+ + + E
Sbjct: 755 SPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
Query: 385 PQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSHRAHSL 444
P +K +P + E I + +P+ + +++ P P + + L
Sbjct: 815 PSIPMEKPTLPTEETTTSVEETTISTEKLTIPME---KPTISTEKPTIPTEKPTISPEKL 871
Query: 445 LFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLP 503
I+ E L +P ++ P+ +E+ T + P +P
Sbjct: 872 TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIP 930
Score = 43.9 bits (102), Expect = 5e-04
Identities = 42/169 (24%), Positives = 63/169 (37%), Gaps = 21/169 (12%)
Query: 269 NSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTS---VPTLESAAAITTKTPSDEREK 325
N+ V+A IN GT K P LPP + ST L I+TK P+ EK
Sbjct: 517 NTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK 576
Query: 326 STCSMGSELLPMISPRSPS---------PPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPP 376
+ + +P P P+ P +P+ P P P P++ ++ E P
Sbjct: 577 PSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIP 636
Query: 377 S---------LDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLP 416
S + E P ++ P + EP IP+ P +P
Sbjct: 637 SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
Score = 37.0 bits (84), Expect = 0.062
Identities = 73/357 (20%), Positives = 122/357 (34%), Gaps = 38/357 (10%)
Query: 6 EEADQPTTEPGMVLDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVL 65
E+ PT +P + + P T + K+ P +K + K T
Sbjct: 736 EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP---TEKPTIPTEKPTIPTE 792
Query: 66 ERKISMRKPREELVKRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEE 125
+ IS +P + + E P E P P++ + T I + + P+ E+
Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPM---EK 849
Query: 126 PVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPL-----------LPPKRP 174
P +++ + IP E K + +E ++P P P+ +P ++P
Sbjct: 850 PT-ISTEKPTIPTE--KPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP 906
Query: 175 LSSSHEASEGQAKDATSSGGTARFIISTSITTAPAA-TTAATSLAKTVNLSVTPSPAPRT 233
S + + K I T T P TT +T T SP T
Sbjct: 907 TISPEKPTISTEKPT----------IPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
Query: 234 LPAAPA--STNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGT-LLSKP 290
+P ST P+ +P ++P IP KP + T L +
Sbjct: 957 IPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALV 1016
Query: 291 SPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPL 347
P P + S + T ++ + T + P + R +S S SPR PL
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPAS----CKSPRPSCGPL 1069
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 58.9 bits (141), Expect = 2e-08
Identities = 131/594 (22%), Positives = 218/594 (36%), Gaps = 73/594 (12%)
Query: 6 EEADQPTT---EPGMV--LDSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKE 60
+E D+ T EPG++ +D ++G TT G + P K+K + E
Sbjct: 846 KEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISE 905
Query: 61 TSEVLERKISMRKPREELVKRGVLLEDPEQGGE--DPGKPSDAMLKN----GHTTPIGNA 114
SE E++ P EE +DPEQ E +PG+P K G T G
Sbjct: 906 ASE--EKRPRPSTPAEEDE------DDPEQEKEAGEPGRPGTKPPKRDEERGKTQ--GKH 955
Query: 115 RSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRP 174
R S + E E S + E+D + + + E
Sbjct: 956 RKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSS 1015
Query: 175 LSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTL 234
S + S+G+ D+TS ++ S+S +++ +++++++S +++ + P L
Sbjct: 1016 KCSLYADSDGE-NDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAAL 1074
Query: 235 PAAPASTNTTATPSLTHMVPAKQPPIPPPKPAHRNSNPVIA----ELSQAINSG-TLLSK 289
P+A P+ PA P+ P P +PV E S A +G T S
Sbjct: 1075 PSASPPPREVPVPT-----PA---PVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESP 1126
Query: 290 PSPPLPPKR---GIPSTSV-PTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSP 345
PS PL P G P+ + P ++ I P +R K+ E++P P +P
Sbjct: 1127 PSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATP 1186
Query: 346 PLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGE 405
P P + P +T + +P +E+ + + R+ ++ E
Sbjct: 1187 PQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAE 1246
Query: 406 PHIPSRLPPLPLHIRIQQALTSP---LPMTPILEGSHR--------------AHSLLFEN 448
P + L + ALT LP P +E S +H LL N
Sbjct: 1247 PG-----TEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHN 1301
Query: 449 ---SDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQC 505
+ + + L +P + P DE E +EE PK Q
Sbjct: 1302 YALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEE-------PKPQQL 1354
Query: 506 LREEEEKESDSDSEGPIQYRDEEDEDESYQSALANKVKRKDTLAMKLNHRPSEP 559
++ EE E + + EG + +EE D S S ++R+ + RP P
Sbjct: 1355 QQQREEGEEEGEEEG--EEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPP 1406
Score = 36.6 bits (83), Expect = 0.082
Identities = 53/241 (21%), Positives = 83/241 (34%), Gaps = 31/241 (12%)
Query: 156 AESVPENVPKP--PLLPPK--RPLSSSHEASEGQA------KDATSSGGTARFIISTSIT 205
AE+ E P LPP+ RP + +A + GG +
Sbjct: 398 AENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVR 457
Query: 206 TAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPP-----I 260
T+P + A S SPAP T + ++ S M+ +Q
Sbjct: 458 TSPRPASPARS----------GSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLA 507
Query: 261 PPPKPAHRNSNPVIA--ELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKT 318
+ NS+ V+ + + SG+ +PP P + E A +
Sbjct: 508 SDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPK 567
Query: 319 PSDEREKSTCSMGSELLPMISPRSPSPP---LPTHIPPEPPRTPPFPAKTFQVVPEIEFP 375
+ + + S CS G ++ R SPP P PP PP PP P +P + +P
Sbjct: 568 ANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLP-LGYP 626
Query: 376 P 376
P
Sbjct: 627 P 627
Score = 32.7 bits (73), Expect = 1.2
Identities = 88/409 (21%), Positives = 133/409 (32%), Gaps = 114/409 (27%)
Query: 106 GHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPK 165
G+ TP S S + ++ P +S + P+ S GS P S+ + +
Sbjct: 238 GNGTPCSQDTSFSSSR-QDTP---SSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTS 293
Query: 166 PPLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSV 225
P + SE +DA S + ST+ +TA AATTAAT+ + + S+
Sbjct: 294 TSFKPRR---------SENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSL 344
Query: 226 TPSPA----------------------------------PRTL-----PAAPASTNTTA- 245
+ S + PR P AP + NT
Sbjct: 345 SSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAER 404
Query: 246 -TPSLTHMVP---------------AKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSK 289
PS T +P ++ PP PP+P + + + +
Sbjct: 405 FPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVR-----TS 459
Query: 290 PSPPLPPKRGIP-----STSVP-----TLESAAAITTK---------TPSDEREKSTCSM 330
P P P + G P + SVP +L+S + K E E+ SM
Sbjct: 460 PRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSM 519
Query: 331 GSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQ 390
++ R +P+ P PP PA V P P +E P+ Q
Sbjct: 520 ------VLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGAT--RESPKANGQ 571
Query: 391 KKEVP------KRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTP 433
+ P I D + G P+ PP QQ P P P
Sbjct: 572 NQASPCSSGDDMEISDDDRGGSPPPAPTPP-------QQPPPPPPPPPP 613
Score = 30.0 bits (66), Expect = 7.6
Identities = 60/241 (24%), Positives = 85/241 (35%), Gaps = 31/241 (12%)
Query: 134 KAIPEEDLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSG 193
+A P E + G G P+ E E V + P+P P R S + E + A S
Sbjct: 431 EAPPPEPPEPGGGGGGGGPSPEREEVRTS-PRPA--SPARSGSPAPETTNESVPFAQHSS 487
Query: 194 GTARFIISTSITTAPAATTAATSLAKTVNLSVT----------PSPA---PRTLPAAPAS 240
+R + + + A+ + + N S+ PS + P T P APA+
Sbjct: 488 LDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPAN 547
Query: 241 TNTTA-TPSLTHMVPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRG 299
A T S + P A S+ E+S G+ P+PP P
Sbjct: 548 FEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPP 607
Query: 300 IPSTSVPTLESAAAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTP 359
P P A+ P + LLP PR PP P + PP PP P
Sbjct: 608 PPPPPPPPPYLASLPLGYPPHQP---------AYLLP---PRPDGPPPPEYPPPPPP--P 653
Query: 360 P 360
P
Sbjct: 654 P 654
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 58.9 bits (141), Expect = 2e-08
Identities = 83/344 (24%), Positives = 122/344 (35%), Gaps = 50/344 (14%)
Query: 110 PIGNARSSSPVQVEEEPVRL---ASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKP 166
P G + S+ P P R + ++ P E + R+ S+ +S+P VP
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 167 PLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVT 226
P RP+ SS GG + S T P T+L S+
Sbjct: 191 P-----RPIQSSPH----NRGSPPVPGGPRQ--PSPGPTPPPFPGNRGTALGGG---SIR 236
Query: 227 PSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPP-------------KPAHRNSNPV 273
SP + +P S P+ + + K PP PPP P +N+ P
Sbjct: 237 QSPLSSS---SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Query: 274 IAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSE 333
+ + S P PP PP R P P L +++ +TP + + S +
Sbjct: 294 VPSTPRPSASS---QAPPPPPPPSRPGP----PPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 334 LLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKE 393
LP P PP P+ PP P R P P ++ + P PP + + + +
Sbjct: 347 PLPSPGRSGPLPPPPSERPPPPVRDP--PGRSGPLPP----PPPVSRNGSTSRALPATPQ 400
Query: 394 VPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEG 437
+P R P R PPLP A P P T I G
Sbjct: 401 LPSR---SGVDSPRSGPR-PPLPPDRPSAGAPPPPPPSTSIRNG 440
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 58.9 bits (141), Expect = 2e-08
Identities = 83/344 (24%), Positives = 122/344 (35%), Gaps = 50/344 (14%)
Query: 110 PIGNARSSSPVQVEEEPVRL---ASLRKAIPEEDLKKRLGSTGSQPNSEAESVPENVPKP 166
P G + S+ P P R + ++ P E + R+ S+ +S+P VP
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 167 PLLPPKRPLSSSHEASEGQAKDATSSGGTARFIISTSITTAPAATTAATSLAKTVNLSVT 226
P RP+ SS GG + S T P T+L S+
Sbjct: 191 P-----RPIQSSPH----NRGSPPVPGGPRQ--PSPGPTPPPFPGNRGTALGGG---SIR 236
Query: 227 PSPAPRTLPAAPASTNTTATPSLTHMVPAKQPPIPPP-------------KPAHRNSNPV 273
SP + +P S P+ + + K PP PPP P +N+ P
Sbjct: 237 QSPLSSS---SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Query: 274 IAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESAAAITTKTPSDEREKSTCSMGSE 333
+ + S P PP PP R P P L +++ +TP + + S +
Sbjct: 294 VPSTPRPSASS---QAPPPPPPPSRPGP----PPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 334 LLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKE 393
LP P PP P+ PP P R P P ++ + P PP + + + +
Sbjct: 347 PLPSPGRSGPLPPPPSERPPPPVRDP--PGRSGPLPP----PPPVSRNGSTSRALPATPQ 400
Query: 394 VPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEG 437
+P R P R PPLP A P P T I G
Sbjct: 401 LPSR---SGVDSPRSGPR-PPLPPDRPSAGAPPPPPPSTSIRNG 440
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 58.9 bits (141), Expect = 2e-08
Identities = 69/270 (25%), Positives = 105/270 (38%), Gaps = 38/270 (14%)
Query: 217 LAKTVNLSVTPSPAPRTLPA-APASTNTTATPSLTHMVPAKQP--------PIPPPKPAH 267
LA + +P+PAPR P P + +P + P P P PP P
Sbjct: 61 LAGLLRAHTSPAPAPRPTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPR 120
Query: 268 RNSNPVIAELSQAINSGTLLSKPS-PPLPPKRGIPSTSVPTLESAAA---ITTKTPSDER 323
R+ P + + T P PPLP KR + SVP + + P+ E
Sbjct: 121 RSCLPPTCFTTPS----TAAPDPVLPPLPAKRHLAELSVPPVPPRTGPPRLLVSLPTKEE 176
Query: 324 EKSTCSMGSELLPM----ISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPEIEFPPSLD 379
E S+ S P +S PP P PP PP PP P + F PE +
Sbjct: 177 ESLLPSLSSPPQPQSEEPLSTLPQGPPQPPSPPPCPPEIPPKPVRLF---PEFDDSD--- 230
Query: 380 LHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPMTPILEGSH 439
+ E+P ++ P R++ + P PSR+P +R+ L+ ++ +G
Sbjct: 231 -YDEVP---EEGPGAPARVMTKKEEPP--PSRVPRA---VRVASLLSEGEELSGDDQGDE 281
Query: 440 RAHSLLFENSDSFSEDSSTLGRTRSLPITI 469
+E + +S+L + SLP TI
Sbjct: 282 EEDDHAYEGVPNGGWHTSSL--SLSLPSTI 309
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,768,865
Number of Sequences: 37866
Number of extensions: 2074439
Number of successful extensions: 26253
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 266
Number of HSP's successfully gapped in prelim test: 1589
Number of HSP's that attempted gapping in prelim test: 13834
Number of HSP's gapped (non-prelim): 8167
length of query: 702
length of database: 18,247,518
effective HSP length: 109
effective length of query: 593
effective length of database: 14,120,124
effective search space: 8373233532
effective search space used: 8373233532
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.