Guide to the Human Genome
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Name: SOS1 Sequence: fasta or formatted (1333aa) NCBI GI: 15529996
Description:

son of sevenless homolog 1

Referenced in:

Inositol Pathways
Ras
Receptor Tyrosine Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         67           2
 C cysteine            1.3         17           2
 D aspartate           4.4         59           2
 E glutamate           9.0        120           2
 F phenylalanine       4.1         54           2
 G glycine             3.5         47           1
 H histidine           3.3         44           2
 I isoleucine          6.5         87           2
 K lysine              6.5         87           2
 L leucine             9.2        122           3
 M methionine          2.1         28           1
 N asparagine          4.0         53           2
 P proline             8.9        119           4
 Q glutamine           4.5         60           2
 R arginine            5.9         78           3
 S serine              8.3        111           3
 T threonine           4.4         58           2
 V valine              5.4         72           2
 W tryptophan          0.7          9           1
 Y tyrosine            3.1         41           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   son of sevenless homolog 1 
SOS2                  0.683   son of sevenless homolog 2 
RASGRF1               0.047   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.047   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF1               0.047   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF2               0.046   Ras protein-specific guanine nucleotide-releasing fa...
RAPGEF1               0.041   guanine nucleotide-releasing factor 2 isoform b [Hom...
RAPGEF1               0.041   guanine nucleotide-releasing factor 2 isoform a [Hom...
RGL1                  0.038   ral guanine nucleotide dissociation stimulator-like ...
RALGPS2               0.033   Ral GEF with PH domain and SH3 binding motif 2 [Homo...
RALGPS1               0.033   Ral GEF with PH domain and SH3 binding motif 1 
RGL3                  0.030   ral guanine nucleotide dissociation stimulator-like...
RGL3                  0.029   ral guanine nucleotide dissociation stimulator-like...
RAPGEF4               0.028   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF4               0.028   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF2               0.024   Rap guanine nucleotide exchange factor 2 
SPATA13               0.023   spermatogenesis associated 13 
RAPGEF5               0.023   Rap guanine nucleotide exchange factor (GEF) 5 [Hom...
RAPGEF6               0.022   PDZ domain-containing guanine nucleotide exchange fa...
RALGDS                0.022   ral guanine nucleotide dissociation stimulator isofo...
RALGDS                0.022   ral guanine nucleotide dissociation stimulator isof...
RASGRP1               0.021   RAS guanyl releasing protein 1 isoform a 
RASGRP3               0.021   RAS guanyl releasing protein 3 (calcium and DAG-reg...
RASGRP3               0.021   RAS guanyl releasing protein 3 (calcium and DAG-regu...
RAPGEFL1              0.021   Rap guanine nucleotide exchange factor (GEF)-like 1 [...
RASGEF1C              0.021   RasGEF domain family, member 1C 
RASGRP3               0.021   RAS guanyl releasing protein 3 (calcium and DAG-regul...
RASGEF1B              0.020   RasGEF domain family, member 1B 
PREX1                 0.020   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
RASGRP1               0.020   RAS guanyl releasing protein 1 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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