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Search of human proteins with 224591414
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224591414 low density lipoprotein receptor class A domain
containing 2 [Homo sapiens]
(272 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224591414 low density lipoprotein receptor class A domain con... 570 e-163
gi|167555125 low density lipoprotein receptor-related protein 3 ... 49 6e-06
gi|11415040 matriptase [Homo sapiens] 47 2e-05
gi|126012573 low density lipoprotein-related protein 2 [Homo sap... 47 2e-05
gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 46 4e-05
gi|93102379 low density lipoprotein-related protein 1B precursor... 45 5e-05
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 43 3e-04
gi|4507157 sortilin-related receptor containing LDLR class A rep... 42 6e-04
gi|208973262 low density lipoprotein-related protein 12 isoform ... 42 6e-04
gi|7305525 low density lipoprotein-related protein 12 isoform a ... 42 6e-04
gi|32490559 low density lipoprotein receptor-related protein 10 ... 41 0.001
gi|65301164 very low density lipoprotein receptor isoform b [Hom... 41 0.001
gi|65301167 very low density lipoprotein receptor isoform a [Hom... 41 0.001
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ... 40 0.003
gi|223942069 enterokinase precursor [Homo sapiens] 40 0.003
gi|189242612 complement component 6 precursor [Homo sapiens] 40 0.003
gi|169636415 complement component 6 precursor [Homo sapiens] 40 0.003
gi|239745038 PREDICTED: hypothetical protein XP_002343338 [Homo ... 39 0.004
gi|157384998 low density lipoprotein receptor-related protein 4 ... 39 0.004
gi|126091152 cubilin [Homo sapiens] 39 0.006
gi|28557796 low density lipoprotein receptor class A domain cont... 38 0.008
gi|4504975 low density lipoprotein receptor precursor [Homo sapi... 38 0.011
gi|29244926 corin [Homo sapiens] 38 0.011
gi|134031945 SCO-spondin [Homo sapiens] 38 0.011
gi|61744471 low density lipoprotein receptor-related protein 8 i... 37 0.018
gi|65301119 low density lipoprotein receptor-related protein 8 i... 37 0.018
gi|4557391 complement component 8, beta polypeptide preproprotei... 37 0.024
gi|13899255 membrane frizzled-related protein [Homo sapiens] 36 0.031
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 36 0.041
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 36 0.041
>gi|224591414 low density lipoprotein receptor class A domain
containing 2 [Homo sapiens]
Length = 272
Score = 570 bits (1469), Expect = e-163
Identities = 272/272 (100%), Positives = 272/272 (100%)
Query: 1 MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAP 60
MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAP
Sbjct: 1 MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAP 60
Query: 61 DTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGPP 120
DTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGPP
Sbjct: 61 DTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGPP 120
Query: 121 GAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQ 180
GAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQ
Sbjct: 121 GAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQ 180
Query: 181 NGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSRSLTPSPAL 240
NGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSRSLTPSPAL
Sbjct: 181 NGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSRSLTPSPAL 240
Query: 241 GSAGSLWIAAERSSPAGRDPTRQDAALEGSTE 272
GSAGSLWIAAERSSPAGRDPTRQDAALEGSTE
Sbjct: 241 GSAGSLWIAAERSSPAGRDPTRQDAALEGSTE 272
>gi|167555125 low density lipoprotein receptor-related protein 3
[Homo sapiens]
Length = 770
Score = 48.5 bits (114), Expect = 6e-06
Identities = 48/171 (28%), Positives = 65/171 (38%), Gaps = 41/171 (23%)
Query: 60 PDTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGP 119
P T+C ++Q GD I FR F V + C+ L GP
Sbjct: 68 PGTNCSWYIQGDR-GDMITISFRNFDVEE---------------SHQCSLDWLLL---GP 108
Query: 120 PGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLG-------- 171
PR LCG IP S+ + + + G+ FRL
Sbjct: 109 AAPPRQEAFRLCGSAIPPAFISARDHVWIFFHSDASSS-----GQAQGFRLSYIRGKLGQ 163
Query: 172 -PCGA-YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVP 220
C A FRC NG+C+P C+ +D CGDGSD+G +C P+ P
Sbjct: 164 ASCQADEFRCDNGKCLPGPWQCNT--VDECGDGSDEG-----NCSAPASEP 207
Score = 32.0 bits (71), Expect = 0.59
Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 5/43 (11%)
Query: 174 GAYFRCQNGR---CIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
G F C R C+P CD G+ +CGDGSD+ C
Sbjct: 214 GGTFPCSGARSTRCLPVERRCD--GLQDCGDGSDEAGCPDLAC 254
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/147 (27%), Positives = 56/147 (38%), Gaps = 26/147 (17%)
Query: 60 PDTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGP 119
P+ DC W ++ +F+FF Y L P PA C P Y++
Sbjct: 362 PNIDC-TWNIEVPNNQHVKVRFKFF--YLLEPG---------VPAGTC-PKDYVEIN--- 405
Query: 120 PGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLG-PCGAYFR 178
G CG V S+ + +R + F+ E S+ PC F
Sbjct: 406 -------GEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFT 458
Query: 179 CQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
C+ GRCI L CD W +C D SD+
Sbjct: 459 CRTGRCIRKELRCDGWA--DCTDHSDE 483
Score = 41.6 bits (96), Expect = 7e-04
Identities = 17/31 (54%), Positives = 22/31 (70%), Gaps = 2/31 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS 207
FRC NG+C+ S C+ G D+CGDGSD+ S
Sbjct: 530 FRCSNGKCLSKSQQCN--GKDDCGDGSDEAS 558
Score = 32.0 bits (71), Expect = 0.59
Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 174 GAYFRCQNGRCIPSSLVCDPWGMDNCGDGSD-QGSWSPA 211
G F C+N C P VCD +++CGD SD QG PA
Sbjct: 491 GHQFTCKNKFCKPLFWVCD--SVNDCGDNSDEQGCSCPA 527
Score = 29.3 bits (64), Expect = 3.8
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 8/55 (14%)
Query: 177 FRCQNGRCIPS-SLVCDPWGMDNCGDGSDQGSWSPADC--RGPSPVPSQTGSTDA 228
+RC NG C+ + CD G ++C DGSD+ DC R + G TDA
Sbjct: 572 YRCLNGLCLSKGNPECD--GKEDCSDGSDE---KDCDCGLRSFTRQARVVGGTDA 621
>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
Length = 4655
Score = 47.0 bits (110), Expect = 2e-05
Identities = 24/51 (47%), Positives = 32/51 (62%), Gaps = 7/51 (13%)
Query: 172 PCGA--YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVP 220
PC + FRC N RCI S VC+ G+D+CGDG+D+ + CR P+P P
Sbjct: 3882 PCNSPNRFRCDNNRCIYSHEVCN--GVDDCGDGTDE---TEEHCRKPTPKP 3927
Score = 41.6 bits (96), Expect = 7e-04
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
FRC+N CIP CD G ++CGD SD+ + +P +C
Sbjct: 3725 FRCKNHHCIPLRWQCD--GQNDCGDNSDEENCAPREC 3759
Score = 41.2 bits (95), Expect = 0.001
Identities = 17/34 (50%), Positives = 25/34 (73%), Gaps = 3/34 (8%)
Query: 173 CGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
CG + F C+NGRC+P+ +CD G+D+C D SD+
Sbjct: 1026 CGLFSFPCKNGRCVPNYYLCD--GVDDCHDNSDE 1057
Score = 40.0 bits (92), Expect = 0.002
Identities = 17/29 (58%), Positives = 21/29 (72%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F CQNGRCI + VCD ++CGDGSD+
Sbjct: 3037 FTCQNGRCISKTFVCDE--DNDCGDGSDE 3063
Score = 39.3 bits (90), Expect = 0.004
Identities = 16/29 (55%), Positives = 21/29 (72%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F+C GRCIPS +CD G ++CGD SD+
Sbjct: 2911 FKCDGGRCIPSEWICD--GDNDCGDMSDE 2937
Score = 39.3 bits (90), Expect = 0.004
Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 3/35 (8%)
Query: 172 PCGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
PC Y ++C NG CIP VCD D+CGD SD+
Sbjct: 3927 PCTEYEYKCGNGHCIPHDNVCD--DADDCGDWSDE 3959
Score = 38.5 bits (88), Expect = 0.006
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTS 231
F+C NGRCI +C+ +D+C D SD+ +C PS TD TS
Sbjct: 3080 FKCDNGRCIEMMKLCN--HLDDCLDNSDEKGCGINECHDPSISGCDHNCTDTLTS 3132
Score = 38.1 bits (87), Expect = 0.008
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C NGRC+ S CD + ++CGDGSD+ DC
Sbjct: 2746 FTCANGRCVQYSYRCDYY--NDCGDGSDEAGCLFRDC 2780
Score = 38.1 bits (87), Expect = 0.008
Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 7/57 (12%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSRS 233
FRC N +CIPS +CD + ++CGD SD+ DC + P T H S
Sbjct: 3764 FRCVNQQCIPSRWICDHY--NDCGDNSDE-----RDCEMRTCHPEYFQCTSGHCVHS 3813
Score = 37.7 bits (86), Expect = 0.011
Identities = 18/30 (60%), Positives = 21/30 (70%), Gaps = 4/30 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDN-CGDGSDQ 205
FRC NGRCIP + CD +DN CGD SD+
Sbjct: 3640 FRCANGRCIPQAWKCD---VDNDCGDHSDE 3666
Score = 37.7 bits (86), Expect = 0.011
Identities = 20/39 (51%), Positives = 23/39 (58%), Gaps = 7/39 (17%)
Query: 172 PCGAY-----FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
P GAY F C+N CIP CD G D+CGDGSD+
Sbjct: 3837 PDGAYCQATMFECKNHVCIPPYWKCD--GDDDCGDGSDE 3873
Score = 37.4 bits (85), Expect = 0.014
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 12/62 (19%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDG--SDQGSWSPADCRGPSPVPSQTGSTDAHTSRSL 234
F C N RCIP +C+ G+DNC D SD+ + C Q+G T H S
Sbjct: 2786 FMCNNRRCIPREFICN--GVDNCHDNNTSDEKNCPDRTC--------QSGYTKCHNSNIC 2835
Query: 235 TP 236
P
Sbjct: 2836 IP 2837
Score = 37.0 bits (84), Expect = 0.018
Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 3/34 (8%)
Query: 173 CGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
CGA F C NGRCI CD ++CGDGSD+
Sbjct: 2700 CGASSFTCSNGRCISEEWKCD--NDNDCGDGSDE 2731
Score = 36.6 bits (83), Expect = 0.024
Identities = 17/31 (54%), Positives = 23/31 (74%), Gaps = 3/31 (9%)
Query: 176 YFRCQN-GRCIPSSLVCDPWGMDNCGDGSDQ 205
YF+CQ+ G+CIP+S VCD +C DGSD+
Sbjct: 71 YFKCQSEGQCIPNSWVCDQ--DQDCDDGSDE 99
Score = 36.6 bits (83), Expect = 0.024
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRG 215
F C NG CIP + VCD ++C DGSD+ + + C G
Sbjct: 188 FSCGNGECIPRAYVCD--HDNDCQDGSDEHACNYPTCGG 224
Score = 36.2 bits (82), Expect = 0.031
Identities = 17/34 (50%), Positives = 21/34 (61%), Gaps = 3/34 (8%)
Query: 173 CGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
CG Y F C +GRCI + VCD G D+C D D+
Sbjct: 222 CGGYQFTCPSGRCIYQNWVCD--GEDDCKDNGDE 253
Score = 35.0 bits (79), Expect = 0.070
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 175 AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCR 214
A+FRC +G CIP+ CD G +C D +D+ + C+
Sbjct: 31 AHFRCGSGHCIPADWRCD--GTKDCSDDADEIGCAVVTCQ 68
Score = 34.7 bits (78), Expect = 0.091
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 175 AYFRCQNGRCIPSSLVCDPWGMDN-CGDGSDQGSWSPADCRGPS 217
+YF C NG CI + +CD DN CGD SD+ R PS
Sbjct: 1274 SYFHCDNGNCIHRAWLCD---RDNDCGDMSDEKDCPTQPFRCPS 1314
Score = 34.3 bits (77), Expect = 0.12
Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 7/38 (18%)
Query: 176 YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
YF+C +G C+ S L CD G +C D SD+ ADC
Sbjct: 3802 YFQCTSGHCVHSELKCD--GSADCLDASDE-----ADC 3832
Score = 33.9 bits (76), Expect = 0.16
Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C N RCI S VCD G +C DGSD+
Sbjct: 1154 FNCPNHRCIDLSFVCD--GDKDCVDGSDE 1180
Score = 33.5 bits (75), Expect = 0.20
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 7/39 (17%)
Query: 179 CQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPS 217
C NG+CIPS CD + +C DG+D+ DC+ P+
Sbjct: 115 CSNGQCIPSEYRCD--HVRDCPDGADEN-----DCQYPT 146
Score = 33.1 bits (74), Expect = 0.27
Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPS 217
+ C N +CI + VCD ++CGDGSD+ + + + PS
Sbjct: 1114 YTCDNHQCISKNWVCDT--DNDCGDGSDEKNCNSTETCQPS 1152
Score = 32.0 bits (71), Expect = 0.59
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 6/37 (16%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C +GRCIP CD +C D SD+ PA C
Sbjct: 2869 FQCASGRCIPQHWYCDQ--ETDCFDASDE----PASC 2899
Score = 32.0 bits (71), Expect = 0.59
Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS 207
++C N RCIP S CD + ++C D SD+ S
Sbjct: 3599 WQCANKRCIPESWQCDTF--NDCEDNSDEDS 3627
Score = 31.6 bits (70), Expect = 0.77
Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ---GSWSPADC 213
F C +G CIP+ CD ++C DGSD+ + +PA C
Sbjct: 1072 FTCGHGECIPAHWRCDK--RNDCVDGSDEHNCPTHAPASC 1109
Score = 31.2 bits (69), Expect = 1.0
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 177 FRCQ-NGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C+ N RCIP VC+ G+D+C D SD+ C
Sbjct: 3684 FSCKTNYRCIPKWAVCN--GVDDCRDNSDEQGCEERTC 3719
>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
Length = 4544
Score = 45.8 bits (107), Expect = 4e-05
Identities = 24/55 (43%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 175 AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAH 229
A F CQN RCI +CD G D+CGDGSD+ A C G + PS H
Sbjct: 2737 AQFECQNHRCISKQWLCD--GSDDCGDGSDEA----AHCEGKTCGPSSFSCPGTH 2785
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/43 (48%), Positives = 25/43 (58%), Gaps = 5/43 (11%)
Query: 173 CGAY-FRCQNGRCIPSSLVCDPWGMDN-CGDGSDQGSWSPADC 213
C Y FRC+N RC+P CD DN CGD SD+ S +P C
Sbjct: 3536 CEPYQFRCKNNRCVPGRWQCD---YDNDCGDNSDEESCTPRPC 3575
Score = 39.3 bits (90), Expect = 0.004
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 173 CGAYFR-CQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTS 231
C FR C NGRC+ + L C+ G D+CGDGSD+ + C G + G+ ++S
Sbjct: 2566 CKKTFRQCSNGRCVSNMLWCN--GADDCGDGSDEIPCNKTAC-GVGEFRCRDGTCIGNSS 2622
Query: 232 R 232
R
Sbjct: 2623 R 2623
Score = 39.3 bits (90), Expect = 0.004
Identities = 20/35 (57%), Positives = 25/35 (71%), Gaps = 4/35 (11%)
Query: 173 CGA-YFRCQN-GRCIPSSLVCDPWGMDNCGDGSDQ 205
CG FRC++ GRCIP+ CD G D+CGDGSD+
Sbjct: 3494 CGVDEFRCKDSGRCIPARWKCD--GEDDCGDGSDE 3526
Score = 38.1 bits (87), Expect = 0.008
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSR 232
F+C +GRCIP CD G ++CGD SD+ + A+C + P TD R
Sbjct: 1020 FKCNSGRCIPEHWTCD--GDNDCGDYSDE---THANCTNQATRPPGGCHTDEFQCR 1070
Score = 37.7 bits (86), Expect = 0.011
Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 5/46 (10%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQ 222
F+C+N RCIP+ +CD G ++CG+ D+ S A C + P+Q
Sbjct: 900 FKCENNRCIPNRWLCD--GDNDCGNSEDE---SNATCSARTCPPNQ 940
Score = 37.7 bits (86), Expect = 0.011
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C +GRC+ +L+C+ G D+CGD SD+ +C
Sbjct: 2910 FLCSSGRCVAEALLCN--GQDDCGDSSDERGCHINEC 2944
Score = 37.0 bits (84), Expect = 0.018
Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 6/44 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVP 220
F C +GRCIP S CD D+CGD SD+ A C P+ P
Sbjct: 941 FSCASGRCIPISWTCDL--DDDCGDRSDES----ASCAYPTCFP 978
Score = 37.0 bits (84), Expect = 0.018
Identities = 21/46 (45%), Positives = 27/46 (58%), Gaps = 6/46 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQ 222
F CQN +CIP VCD +C DGSD+ SP +C P+ PS+
Sbjct: 2823 FMCQNRQCIPKHFVCD--HDRDCADGSDE---SP-ECEYPTCGPSE 2862
Score = 37.0 bits (84), Expect = 0.018
Identities = 16/29 (55%), Positives = 22/29 (75%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C+N RC+ SSL C+ + D+CGDGSD+
Sbjct: 3747 FLCRNQRCLSSSLRCNMF--DDCGDGSDE 3773
Score = 36.6 bits (83), Expect = 0.024
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 8/47 (17%)
Query: 177 FRCQN-GRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQ 222
F+C N RCIP C+ G DNCGDG D+ DC + P+Q
Sbjct: 3418 FKCTNTNRCIPGIFRCN--GQDNCGDGEDE-----RDCPEVTCAPNQ 3457
Score = 36.2 bits (82), Expect = 0.031
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 172 PCG-AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSP 210
PC + F C NGRCI CD G +C DGSD+ +P
Sbjct: 3574 PCSESEFSCANGRCIAGRWKCD--GDHDCADGSDEKDCTP 3611
Score = 35.0 bits (79), Expect = 0.070
Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 8/42 (19%)
Query: 177 FRCQNGR-CIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPS 217
FRC+N R C+ CD G DNCGDG+D+ DC P+
Sbjct: 3701 FRCKNDRVCLWIGRQCD--GTDNCGDGTDE-----EDCEPPT 3735
Score = 33.9 bits (76), Expect = 0.16
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 15/57 (26%)
Query: 166 TSFRLGPCG---------AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
T+F LG G + F C+N +CIP CD D+CGD SD+ P DC
Sbjct: 3319 TNFYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDT--EDDCGDHSDE----PPDC 3369
Score = 33.9 bits (76), Expect = 0.16
Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 5/37 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C N C P + CD G D+CGD SD+ +P +C
Sbjct: 3659 FQCNNTLCKPLAWKCD--GEDDCGDNSDE---NPEEC 3690
Score = 33.5 bits (75), Expect = 0.20
Identities = 15/29 (51%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C NG CI SL CD G+ +C D SD+
Sbjct: 2530 FECANGECINFSLTCD--GVPHCKDKSDE 2556
Score = 33.1 bits (74), Expect = 0.27
Identities = 13/23 (56%), Positives = 17/23 (73%), Gaps = 2/23 (8%)
Query: 184 CIPSSLVCDPWGMDNCGDGSDQG 206
C+P +CD G D+CGDGSD+G
Sbjct: 1159 CLPPDKLCD--GNDDCGDGSDEG 1179
Score = 32.7 bits (73), Expect = 0.35
Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 3/42 (7%)
Query: 173 CGA-YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
CG FRC++G CI +S C+ + +C D SD+ + S DC
Sbjct: 2605 CGVGEFRCRDGTCIGNSSRCNQF--VDCEDASDEMNCSATDC 2644
Score = 32.3 bits (72), Expect = 0.45
Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWS 209
F C NGRCI + CD ++CGD SD+ S
Sbjct: 982 FTCNNGRCININWRCD--NDNDCGDNSDEAGCS 1012
Score = 32.0 bits (71), Expect = 0.59
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 3/42 (7%)
Query: 177 FRCQNG-RCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPS 217
F C++ RCI + VCD G ++C D SD+ + CR PS
Sbjct: 1110 FGCKDSARCISKAWVCD--GDNDCEDNSDEENCESLACRPPS 1149
Score = 32.0 bits (71), Expect = 0.59
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 4/40 (10%)
Query: 173 CG-AYFRCQNGRCIPS-SLVCDPWGMDNCGDGSDQGSWSP 210
CG + FRC NGRC+ S CD G ++C D SD+ +P
Sbjct: 2858 CGPSEFRCANGRCLSSRQWECD--GENDCHDQSDEAPKNP 2895
Score = 29.3 bits (64), Expect = 3.8
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 5/37 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C N RCI CD G ++C D SD+ +PA C
Sbjct: 859 FACANSRCIQERWKCD--GDNDCLDNSDE---APALC 890
Score = 29.3 bits (64), Expect = 3.8
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 7/53 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAH 229
F+C G C + +CD G ++C D SD+ A+C +PSQ T+ +
Sbjct: 3379 FQCSTGICTNPAFICD--GDNDCQDNSDE-----ANCDIHVCLPSQFKCTNTN 3424
Score = 29.3 bits (64), Expect = 3.8
Identities = 13/29 (44%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F+C++G CIP CD +C DGSD+
Sbjct: 3618 FQCKSGHCIPLRWRCD--ADADCMDGSDE 3644
Score = 28.5 bits (62), Expect = 6.5
Identities = 11/23 (47%), Positives = 17/23 (73%), Gaps = 2/23 (8%)
Query: 184 CIPSSLVCDPWGMDNCGDGSDQG 206
C+P S +C+ G+ +C DGSD+G
Sbjct: 85 CVPMSRLCN--GVQDCMDGSDEG 105
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 45.4 bits (106), Expect = 5e-05
Identities = 19/39 (48%), Positives = 27/39 (69%), Gaps = 2/39 (5%)
Query: 175 AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
++F C+NGRCIPS +CD D+CGDGSD+ + +C
Sbjct: 2894 SFFMCKNGRCIPSGGLCD--NKDDCGDGSDERNCHINEC 2930
Score = 41.6 bits (96), Expect = 7e-04
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 160 DFVGEVTSFRLGPCGA-YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
D G +++ PC F C N +CIP L CD +D+CGDGSD+
Sbjct: 3749 DHCGGKLTYKARPCKKDEFACSNKKCIPMDLQCD--RLDDCGDGSDE 3793
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 10/47 (21%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS--------WSPADCRG 215
FRC +GRCIP CD G ++CGD SD+ SPA C G
Sbjct: 1011 FRCSSGRCIPGHWACD--GDNDCGDFSDEAQINCTKEEIHSPAGCNG 1055
Score = 38.5 bits (88), Expect = 0.006
Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPA 211
FRC NG+CIP+ CD G ++C G D+ S PA
Sbjct: 3558 FRCSNGQCIPAKWKCD--GHEDCKYGEDEKSCEPA 3590
Score = 37.7 bits (86), Expect = 0.011
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 6/37 (16%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
FRC+ +CIP CD +D+CGDGSD+ P DC
Sbjct: 3322 FRCKTDKCIPFWWKCDT--VDDCGDGSDE----PDDC 3352
Score = 37.0 bits (84), Expect = 0.018
Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS 207
F+CQN RCIP +CD G ++CG D+ +
Sbjct: 891 FKCQNNRCIPKRWLCD--GANDCGSNEDESN 919
Score = 37.0 bits (84), Expect = 0.018
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 6/44 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVP 220
F C NGRCIP + +CD D+CGD +D+ A C P+ P
Sbjct: 932 FSCGNGRCIPRAWLCD--REDDCGDQTDE----MASCEFPTCEP 969
Score = 36.6 bits (83), Expect = 0.024
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 173 CGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
CG + F+C+N CIP CD ++C D SD+ + P C
Sbjct: 3476 CGPHEFQCKNNNCIPDHWRCD--SQNDCSDNSDEENCKPQTC 3515
Score = 36.2 bits (82), Expect = 0.031
Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C N CIP VCD D+CGDGSD+
Sbjct: 2810 FMCHNKVCIPKQFVCD--HDDDCGDGSDE 2836
Score = 35.8 bits (81), Expect = 0.041
Identities = 16/29 (55%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C++GRCI S CD D+CGDGSD+
Sbjct: 973 FVCKSGRCISSKWHCD--SDDDCGDGSDE 999
Score = 35.0 bits (79), Expect = 0.070
Identities = 14/30 (46%), Positives = 20/30 (66%), Gaps = 2/30 (6%)
Query: 176 YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
YF C +GRCI ++ +CD G +C DG D+
Sbjct: 2686 YFSCPSGRCILNTWICD--GQKDCEDGRDE 2713
Score = 34.7 bits (78), Expect = 0.091
Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 4/35 (11%)
Query: 173 CGAY--FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
C AY F C NG CI L CD G+ +C D SD+
Sbjct: 2510 CNAYSEFECGNGECIDYQLTCD--GIPHCKDKSDE 2542
Score = 34.3 bits (77), Expect = 0.12
Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS 207
FRC+N CI + CD G D+C DGSD+ S
Sbjct: 850 FRCKNRHCIQARWKCD--GDDDCLDGSDEDS 878
Score = 34.3 bits (77), Expect = 0.12
Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 179 CQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
C N RCIP +CD G ++CGD SD+ + C
Sbjct: 2559 CYNRRCIPHGKLCD--GENDCGDNSDELDCKVSTC 2591
Score = 33.1 bits (74), Expect = 0.27
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
FRC +G CIP S C+ +C D SD+ + + DC
Sbjct: 2596 FRCADGTCIPRSARCNQ--NIDCADASDEKNCNNTDC 2630
Score = 31.6 bits (70), Expect = 0.77
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C +CI +CD G D+CGDG D+
Sbjct: 2725 FACSAQKCISKHWICD--GEDDCGDGLDE 2751
Score = 31.6 bits (70), Expect = 0.77
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 3/38 (7%)
Query: 177 FRC-QNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C +N +CIP +L C+ G D+CGD D+ C
Sbjct: 3401 FKCTKNQKCIPVNLRCN--GQDDCGDEEDERDCPENSC 3436
Score = 31.6 bits (70), Expect = 0.77
Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 3/29 (10%)
Query: 178 RCQNGR-CIPSSLVCDPWGMDNCGDGSDQ 205
RC+N R C+ S +C+ G+D CGD SD+
Sbjct: 3722 RCRNNRICLQSEQMCN--GIDECGDNSDE 3748
Score = 31.2 bits (69), Expect = 1.0
Identities = 14/29 (48%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C NG C+ S CD G +C DGSD+
Sbjct: 3520 FLCANGDCVSSRFWCD--GDFDCADGSDE 3546
Score = 30.4 bits (67), Expect = 1.7
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F+C G C + +CD G ++CGD SD+
Sbjct: 3362 FQCGTGLCALPAFICD--GENDCGDNSDE 3388
Score = 29.6 bits (65), Expect = 2.9
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C N C VCD G D+CGD SD+
Sbjct: 3679 FLCNNSLCKLHFWVCD--GEDDCGDNSDE 3705
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 43.1 bits (100), Expect = 3e-04
Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 22/117 (18%)
Query: 133 LNIPVPVASSGPFLGLRLVTRG----------RQPRVDFVGEVT---SFRLGPCGAY-FR 178
LN PV P L + T RQP V + S R PCG
Sbjct: 232 LNCEEPVLGISPTFSLLVETTSLPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAA 291
Query: 179 CQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPV-PSQTGSTDAHTSRSL 234
C+NG CIP +CD G ++C DGSD+ DC P P P++ + H + L
Sbjct: 292 CRNGHCIPRDYLCD--GQEDCEDGSDE-----LDCGPPPPCEPNEFPCGNGHCALKL 341
Score = 28.1 bits (61), Expect = 8.5
Identities = 42/163 (25%), Positives = 52/163 (31%), Gaps = 30/163 (18%)
Query: 96 LNTSSPAPADPCAPG-------SYLQFYEG----PPGAPRPLGSPLCGLNIPVPVASSGP 144
L+T A D CAPG S YEG P G RP+ + + + +SG
Sbjct: 831 LDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGE 890
Query: 145 FLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSD 204
+ GR G P G C C+ S C
Sbjct: 891 ACRCKNNVVGRLCNECADGSFHLSTRNPDG----CLKCFCMGVSRHC------------T 934
Query: 205 QGSWSPADCRGPSPVP---SQTGSTDAHTSRSLTPSPALGSAG 244
SWS A G S P S T + HT+ SP G G
Sbjct: 935 SSSWSRAQLHGASEEPGHFSLTNAASTHTTNEGIFSPTPGELG 977
>gi|4507157 sortilin-related receptor containing LDLR class A repeats
preproprotein [Homo sapiens]
Length = 2214
Score = 42.0 bits (97), Expect = 6e-04
Identities = 19/34 (55%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSP 210
FRC NG CIPSS CD G+ +C DGSD+ P
Sbjct: 1242 FRCPNGTCIPSSKHCD--GLRDCSDGSDEQHCEP 1273
Score = 42.0 bits (97), Expect = 6e-04
Identities = 21/45 (46%), Positives = 27/45 (60%), Gaps = 7/45 (15%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPS 221
F+CQNG CI CD GMD+CGD SD+ A+C P+ P+
Sbjct: 1330 FQCQNGVCISLIWKCD--GMDDCGDYSDE-----ANCENPTEAPN 1367
Score = 37.4 bits (85), Expect = 0.014
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 5/37 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C+NG CIP CD G +C DGSD+ P +C
Sbjct: 1204 FQCRNGHCIPQRWACD--GDTDCQDGSDE---DPVNC 1235
Score = 37.4 bits (85), Expect = 0.014
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 176 YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTD 227
Y+RC +G C+ + VCD G +C DGSD+ + + P+Q G D
Sbjct: 1423 YYRCSSGTCVMDTWVCD--GYRDCADGSDEEACPLLANVTAASTPTQLGRCD 1472
Score = 37.0 bits (84), Expect = 0.018
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 9/53 (16%)
Query: 173 CGAYF--RCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQT 223
C YF RC+NG CIP+ CD ++CGD SD+ DC +P T
Sbjct: 1368 CSRYFQFRCENGHCIPNRWKCD--RENDCGDWSDE-----KDCGDSHILPFST 1413
Score = 36.2 bits (82), Expect = 0.031
Identities = 19/39 (48%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 177 FRCQ-NGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCR 214
FRCQ +G CIP S CD D+CGD SD+ CR
Sbjct: 1123 FRCQESGTCIPLSYKCDL--EDDCGDNSDESHCEMHQCR 1159
Score = 31.6 bits (70), Expect = 0.77
Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS 207
+ C +G CI SS VCD G ++C D SD+ +
Sbjct: 1163 YNCSSGMCIRSSWVCD--GDNDCRDWSDEAN 1191
Score = 31.2 bits (69), Expect = 1.0
Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 4/38 (10%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDN-CGDGSDQGSWSPADC 213
+RC NG CI S CD DN CGD SD+ + C
Sbjct: 1083 YRCSNGNCINSIWWCD---FDNDCGDMSDERNCPTTIC 1117
>gi|208973262 low density lipoprotein-related protein 12 isoform b
precursor [Homo sapiens]
Length = 840
Score = 42.0 bits (97), Expect = 6e-04
Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 131 CGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGP--CGA-YFRCQNGRCIPS 187
CG IP P SS + +R + R F S + C FRC NG+CIP
Sbjct: 103 CGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPE 162
Query: 188 SLVCDPWGMDNCGDGSDQ 205
+ C+ MD CGD SD+
Sbjct: 163 AWKCN--NMDECGDSSDE 178
Score = 38.9 bits (89), Expect = 0.005
Identities = 16/29 (55%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C+N RC+ S VCD D+CGDGSD+
Sbjct: 437 FHCKNNRCVFESWVCD--SQDDCGDGSDE 463
>gi|7305525 low density lipoprotein-related protein 12 isoform a
precursor [Homo sapiens]
Length = 859
Score = 42.0 bits (97), Expect = 6e-04
Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 131 CGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGP--CGA-YFRCQNGRCIPS 187
CG IP P SS + +R + R F S + C FRC NG+CIP
Sbjct: 122 CGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPE 181
Query: 188 SLVCDPWGMDNCGDGSDQ 205
+ C+ MD CGD SD+
Sbjct: 182 AWKCN--NMDECGDSSDE 197
Score = 38.9 bits (89), Expect = 0.005
Identities = 16/29 (55%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C+N RC+ S VCD D+CGDGSD+
Sbjct: 456 FHCKNNRCVFESWVCD--SQDDCGDGSDE 482
>gi|32490559 low density lipoprotein receptor-related protein 10
precursor [Homo sapiens]
Length = 713
Score = 41.2 bits (95), Expect = 0.001
Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRG--PSPVPS 221
F+C N RC+ + CD G+D CGDGSD+ S G P PVPS
Sbjct: 145 FQCLNHRCVSAVQRCD--GVDACGDGSDEAGCSSDPFPGLTPRPVPS 189
Score = 33.5 bits (75), Expect = 0.20
Identities = 13/29 (44%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
FRC++ +C+ + VCD G +C DGSD+
Sbjct: 404 FRCRDEKCVYETWVCD--GQPDCADGSDE 430
>gi|65301164 very low density lipoprotein receptor isoform b [Homo
sapiens]
Length = 845
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C +GRCI + VC+ G D+C DGSD+ +P C
Sbjct: 159 FTCSSGRCISRNFVCN--GQDDCSDGSDELDCAPPTC 193
Score = 37.0 bits (84), Expect = 0.018
Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 5/37 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C NG+C+PS CD G +C DGSD+ SP C
Sbjct: 77 FVCNNGQCVPSRWKCD--GDPDCEDGSDE---SPEQC 108
Score = 33.5 bits (75), Expect = 0.20
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C NGRCI CD G ++C DGSD+ + C
Sbjct: 38 FQCTNGRCITLLWKCD--GDEDCVDGSDEKNCVKKTC 72
Score = 33.1 bits (74), Expect = 0.27
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPAD-CRGPSPVPSQTG 224
F C++G CI S C+ G+ +C DGSD+ + + C GP ++G
Sbjct: 283 FECEDGSCIHGSRQCN--GIRDCVDGSDEVNCKNVNQCLGPGKFKCRSG 329
Score = 32.3 bits (72), Expect = 0.45
Identities = 21/48 (43%), Positives = 24/48 (50%), Gaps = 7/48 (14%)
Query: 173 CGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPV 219
CGA+ F+C CIP S VC D+ D SDQ S C G PV
Sbjct: 193 CGAHEFQCSTSSCIPISWVC-----DDDADCSDQSDESLEQC-GRQPV 234
Score = 28.1 bits (61), Expect = 8.5
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 4/36 (11%)
Query: 170 LGPCGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
LGP F+C++G CI S VC+ +C D SD+
Sbjct: 319 LGP--GKFKCRSGECIDISKVCNQ--EQDCRDWSDE 350
>gi|65301167 very low density lipoprotein receptor isoform a [Homo
sapiens]
Length = 873
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C +GRCI + VC+ G D+C DGSD+ +P C
Sbjct: 159 FTCSSGRCISRNFVCN--GQDDCSDGSDELDCAPPTC 193
Score = 37.0 bits (84), Expect = 0.018
Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 5/37 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C NG+C+PS CD G +C DGSD+ SP C
Sbjct: 77 FVCNNGQCVPSRWKCD--GDPDCEDGSDE---SPEQC 108
Score = 33.5 bits (75), Expect = 0.20
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C NGRCI CD G ++C DGSD+ + C
Sbjct: 38 FQCTNGRCITLLWKCD--GDEDCVDGSDEKNCVKKTC 72
Score = 33.1 bits (74), Expect = 0.27
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPAD-CRGPSPVPSQTG 224
F C++G CI S C+ G+ +C DGSD+ + + C GP ++G
Sbjct: 283 FECEDGSCIHGSRQCN--GIRDCVDGSDEVNCKNVNQCLGPGKFKCRSG 329
Score = 32.3 bits (72), Expect = 0.45
Identities = 21/48 (43%), Positives = 24/48 (50%), Gaps = 7/48 (14%)
Query: 173 CGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPV 219
CGA+ F+C CIP S VC D+ D SDQ S C G PV
Sbjct: 193 CGAHEFQCSTSSCIPISWVC-----DDDADCSDQSDESLEQC-GRQPV 234
Score = 28.1 bits (61), Expect = 8.5
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 4/36 (11%)
Query: 170 LGPCGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
LGP F+C++G CI S VC+ +C D SD+
Sbjct: 319 LGP--GKFKCRSGECIDISKVCNQ--EQDCRDWSDE 350
>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
sapiens]
Length = 800
Score = 39.7 bits (91), Expect = 0.003
Identities = 55/194 (28%), Positives = 71/194 (36%), Gaps = 36/194 (18%)
Query: 82 RFFLVYSLTPA----PPALNTSSPAPADPCAPGSYLQFYEGPPGAPRPLGSPLCGLNIPV 137
R F+VY + PPA +T P P G F GPP P P G P P
Sbjct: 273 RMFIVYHVAAGLPILPPAGHTLRLPPRSPPRLGRAPHF-NGPPAHPGP-GRPSTS---PC 327
Query: 138 PVASSGPFLGLRLVT-RGRQPRVDFVGEVTSFRLGPCGAYFRCQNGRCIPSSLVCDPWGM 196
P+ S L + T RGRQ + V + G+ +P G
Sbjct: 328 PLPPSLLCLWVESGTPRGRQSLAEGV---------------KRDGGQGLPDVEGAPDMGS 372
Query: 197 DNCGDGSDQGS-------WSPADCRGPSPVPSQTGSTDAHTSRSLTPSPAL---GSAGSL 246
G G ++GS W P R P+P ++ G T + + PSP G GSL
Sbjct: 373 SGEGAGLEEGSPLRRERAWPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKTELGGPQGSL 432
Query: 247 WIAAERSSPAGRDP 260
A S P G P
Sbjct: 433 G-RASLSGPFGPGP 445
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 39.7 bits (91), Expect = 0.003
Identities = 23/52 (44%), Positives = 31/52 (59%), Gaps = 11/52 (21%)
Query: 166 TSFRLG---PCGA-YFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
T + LG PC A +F+C+NG C+P +CD G +C DGSD+ ADC
Sbjct: 633 TGYHLGIPEPCKADHFQCKNGECVPLVNLCD--GHLHCEDGSDE-----ADC 677
>gi|189242612 complement component 6 precursor [Homo sapiens]
Length = 934
Score = 39.7 bits (91), Expect = 0.003
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 17/73 (23%)
Query: 173 CGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSR 232
C FRC +GRCI L C+ G ++CGD SD+ DC G T A +R
Sbjct: 140 CKNKFRCDSGRCIARKLECN--GENDCGDNSDE-----RDC----------GRTKAVCTR 182
Query: 233 SLTPSPALGSAGS 245
P P++ G+
Sbjct: 183 KYNPIPSVQLMGN 195
>gi|169636415 complement component 6 precursor [Homo sapiens]
Length = 934
Score = 39.7 bits (91), Expect = 0.003
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 17/73 (23%)
Query: 173 CGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSR 232
C FRC +GRCI L C+ G ++CGD SD+ DC G T A +R
Sbjct: 140 CKNKFRCDSGRCIARKLECN--GENDCGDNSDE-----RDC----------GRTKAVCTR 182
Query: 233 SLTPSPALGSAGS 245
P P++ G+
Sbjct: 183 KYNPIPSVQLMGN 195
>gi|239745038 PREDICTED: hypothetical protein XP_002343338 [Homo
sapiens]
Length = 244
Score = 39.3 bits (90), Expect = 0.004
Identities = 44/147 (29%), Positives = 56/147 (38%), Gaps = 25/147 (17%)
Query: 89 LTPAPPALNTSSPAPADPCAPGSYLQFYEGPPGAPRPLGSPLCGLNIPVPVASSG-PFLG 147
++PAPP TS +P A L P APRP C VPVA G P G
Sbjct: 101 ISPAPPGPPTSRQSPRISVAAAPVL------PAAPRPPTQRRC-----VPVAQRGLPLCG 149
Query: 148 LRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS 207
L R+P +GE A FR C P + P + CG + +G
Sbjct: 150 TGLGLETRRPARSCLGET--------AAPFRFPRCECKPPT----PQRLHPCGLQTHRGV 197
Query: 208 WSPADCRGPSPVPSQTGSTDAHTSRSL 234
+ P R + S TDA T R +
Sbjct: 198 FIPVGYR-RTAASSSLWVTDAQTHRGV 223
>gi|157384998 low density lipoprotein receptor-related protein 4
[Homo sapiens]
Length = 1905
Score = 39.3 bits (90), Expect = 0.004
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTG 224
F C NG+CI S VCD G ++C D SD+ P +C P Q G
Sbjct: 76 FHCDNGKCIRRSWVCD--GDNDCEDDSDEQDCPPRECE-EDEFPCQNG 120
Score = 35.0 bits (79), Expect = 0.070
Identities = 15/29 (51%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
FRC +GRC+ S CD G D+C D SD+
Sbjct: 275 FRCHSGRCVRLSWRCD--GEDDCADNSDE 301
Score = 34.3 bits (77), Expect = 0.12
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 8/51 (15%)
Query: 172 PCGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPS 221
PC F+C GRCI CD G D+CGD SD+ +DC P S
Sbjct: 190 PCNLEEFQCAYGRCILDIYHCD--GDDDCGDWSDE-----SDCSSHQPCRS 233
Score = 33.9 bits (76), Expect = 0.16
Identities = 16/29 (55%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F CQNG CI S CD G ++CGD SD+
Sbjct: 115 FPCQNGYCIRSLWHCD--GDNDCGDNSDE 141
Score = 33.9 bits (76), Expect = 0.16
Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C NGRCI +C+ G+++CGD SD+
Sbjct: 317 FLCWNGRCIGQRKLCN--GVNDCGDNSDE 343
Score = 32.3 bits (72), Expect = 0.45
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 7/44 (15%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVP 220
FRC +G CI CD G +C DGSD+ +C P P
Sbjct: 153 FRCSDGSCIAEHWYCD--GDTDCKDGSDE-----ENCPSAVPAP 189
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 38.5 bits (88), Expect = 0.006
Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 20/123 (16%)
Query: 60 PDTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGP 119
P DC +W+ AA P RI+ QF +TP N +S +YL+ +G
Sbjct: 2243 PHADC-IWILAAPPETRIQLQFEDRFDIEVTP-----NCTS----------NYLELRDG- 2285
Query: 120 PGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRC 179
+ P+ S CG ++P SSG + LR + V F + + + CG
Sbjct: 2286 VDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAK---YSIAQCGGRVPG 2342
Query: 180 QNG 182
Q+G
Sbjct: 2343 QSG 2345
Score = 31.2 bits (69), Expect = 1.0
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 112 YLQFYEGPPGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLG 171
Y++ Y+G G+ CG +P P SSG FL ++ ++ R F T +
Sbjct: 3219 YVKLYDGDSENANLAGT-FCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIMDM- 3276
Query: 172 PCGAYF 177
PCG +
Sbjct: 3277 PCGGTY 3282
Score = 30.0 bits (66), Expect = 2.2
Identities = 21/70 (30%), Positives = 28/70 (40%), Gaps = 12/70 (17%)
Query: 130 LCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQNG------- 182
LCG IP P+ S+G ++ +R + R F SF CG Y G
Sbjct: 2053 LCGREIPGPIRSTGEYMFIRFTSDSSVTRAGF---NASFHKS-CGGYLHADRGIITSPKY 2108
Query: 183 -RCIPSSLVC 191
PS+L C
Sbjct: 2109 PETYPSNLNC 2118
>gi|28557796 low density lipoprotein receptor class A domain
containing 3 [Homo sapiens]
Length = 345
Score = 38.1 bits (87), Expect = 0.008
Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCR-GPSPVPSQTG 224
F C NGRCIP + CD G+ +C D SD+ A + GP+ P +G
Sbjct: 35 FMCSNGRCIPGAWQCD--GLPDCFDKSDEKECPKAKSKCGPTFFPCASG 81
Score = 37.7 bits (86), Expect = 0.011
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 2/33 (6%)
Query: 175 AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGS 207
A + C+NG CI S +CD G +NC D SD+ S
Sbjct: 116 ARYHCKNGLCIDKSFICD--GQNNCQDNSDEES 146
>gi|4504975 low density lipoprotein receptor precursor [Homo
sapiens]
Length = 860
Score = 37.7 bits (86), Expect = 0.011
Identities = 20/44 (45%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 172 PCGAY-FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCR 214
PC A+ F C +G CI SS CD G +C D SD+ + + A CR
Sbjct: 196 PCSAFEFHCLSGECIHSSWRCD--GGPDCKDKSDEENCAVATCR 237
Score = 35.0 bits (79), Expect = 0.070
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPS 217
FRC +G+CI VCD +C DGSD+ S C GP+
Sbjct: 114 FRCHDGKCISRQFVCD--SDRDCLDGSDEASCPVLTC-GPA 151
Score = 34.7 bits (78), Expect = 0.091
Identities = 15/29 (51%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F+CQ+G+CI VCD G C DGSD+
Sbjct: 32 FQCQDGKCISYKWVCD--GSAECQDGSDE 58
Score = 34.3 bits (77), Expect = 0.12
Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 6/44 (13%)
Query: 173 CG-AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRG 215
CG A F+C + CIP CD +C DGSD+ W P CRG
Sbjct: 148 CGPASFQCNSSTCIPQLWACD--NDPDCEDGSDE--W-PQRCRG 186
Score = 28.9 bits (63), Expect = 5.0
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 3/49 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ-GSWSPADCRGPSPVPSQTG 224
F+C +G CI S CD +C D SD+ G + C GP+ +G
Sbjct: 241 FQCSDGNCIHGSRQCD--REYDCKDMSDEVGCVNVTLCEGPNKFKCHSG 287
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 37.7 bits (86), Expect = 0.011
Identities = 16/31 (51%), Positives = 23/31 (74%), Gaps = 2/31 (6%)
Query: 179 CQNGRCIPSSLVCDPWGMDNCGDGSDQGSWS 209
C+NG+CIPS+ CD G ++C DGSD+ + S
Sbjct: 387 CRNGQCIPSTFQCD--GDEDCKDGSDEENCS 415
Score = 37.4 bits (85), Expect = 0.014
Identities = 16/29 (55%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
F C G+C+ SLVCD G D+CGD SD+
Sbjct: 311 FHCHTGKCLNYSLVCD--GYDDCGDLSDE 337
Score = 31.6 bits (70), Expect = 0.77
Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 7/49 (14%)
Query: 178 RCQNGRCIPSSLVCDPWGMDNCGDGSDQ-----GSWSPADCRGPSPVPS 221
RC +GRCI VCD G +C D SD+ S +CR +PS
Sbjct: 349 RCGDGRCIAMEWVCD--GDHDCVDKSDEVNCSCHSQGLVECRNGQCIPS 395
Score = 31.6 bits (70), Expect = 0.77
Identities = 12/31 (38%), Positives = 22/31 (70%), Gaps = 2/31 (6%)
Query: 175 AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
++F+C++G+C+ +S CD G +C D SD+
Sbjct: 583 SHFKCRSGQCVLASRRCD--GQADCDDDSDE 611
Score = 31.2 bits (69), Expect = 1.0
Identities = 14/32 (43%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 174 GAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQ 205
G F C +G CIP L C+ G ++C D SD+
Sbjct: 272 GENFLCASGICIPGKLQCN--GYNDCDDWSDE 301
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 37.7 bits (86), Expect = 0.011
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 3/37 (8%)
Query: 173 CG-AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSW 208
CG C +G C+P +L+CD D+CGDG+D+ S+
Sbjct: 1416 CGEGQMTCSSGHCLPLALLCD--RQDDCGDGTDEPSY 1450
Score = 37.4 bits (85), Expect = 0.014
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 22/101 (21%)
Query: 117 EGPPGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAY 176
EGP P P ++P P AS+ P + P ++ PCG +
Sbjct: 1523 EGPGHCPLP--------SLPTPPASTLPGPSPGSLDTASSPLA------SASPAPPCGPF 1568
Query: 177 -FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGP 216
FRC +G C P CD ++C DGSD+ C GP
Sbjct: 1569 EFRCGSGECTPRGWRCDQ--EEDCADGSDE-----RGCGGP 1602
Score = 36.2 bits (82), Expect = 0.031
Identities = 14/34 (41%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
Query: 180 QNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
+NG C+P +CD D+CGDGSD+ + C
Sbjct: 1385 ENGHCVPHGWLCD--NQDDCGDGSDEEGCAAPGC 1416
Score = 35.0 bits (79), Expect = 0.070
Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
Query: 141 SSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCG-AYFRCQNGRCIPSSLVCDPWGMDNC 199
SSG L L L+ R D G+ T PC C +GRC+P +L+CD G +C
Sbjct: 1424 SSGHCLPLALLC----DRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCD--GHPDC 1477
Query: 200 GDGSDQGS 207
D +D+ S
Sbjct: 1478 LDAADEES 1485
Score = 32.3 bits (72), Expect = 0.45
Identities = 42/136 (30%), Positives = 57/136 (41%), Gaps = 23/136 (16%)
Query: 101 PAPADPCAPGSYLQFYEGP-PGAPRPLGSPLCGLNIPVPVASSGPFL----GLRLVTRG- 154
P P+ P P S L GP PG+ SPL + P GPF RG
Sbjct: 1529 PLPSLPTPPASTLP---GPSPGSLDTASSPLASAS---PAPPCGPFEFRCGSGECTPRGW 1582
Query: 155 RQPRVDFVGEVTSFRL--GPCGAYFR-CQNG-RCIPSSLVCDPWGMDNCGDGSDQGSWSP 210
R + + + + R GPC + C G C+ +CD G+ C DGSD+G P
Sbjct: 1583 RCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQLCD--GVRQCPDGSDEG---P 1637
Query: 211 ADCRGPSPV--PSQTG 224
C G + P++TG
Sbjct: 1638 DACGGLPALGGPNRTG 1653
Score = 32.3 bits (72), Expect = 0.45
Identities = 45/168 (26%), Positives = 61/168 (36%), Gaps = 48/168 (28%)
Query: 91 PAPPALNTSSP-----APADPCAPGSYL--------------QFYEGPPGAP-RPLGSPL 130
P+P +L+T+S +PA PC P + Q + G+ R G P
Sbjct: 1544 PSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPC 1603
Query: 131 CGLNIPVPVASSGPFL--------GLRLVTRGRQPRVDFVGEVTSF----RLG-PCGAYF 177
+ P + GP G+R G D G + + R G PC Y
Sbjct: 1604 APHHAP---CARGPHCVSPEQLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEY- 1659
Query: 178 RCQNGRCIPSSLVCDPWGMDNCG---------DGSDQGSWSPADCRGP 216
C NG CI LVCD G +CG + G+W P GP
Sbjct: 1660 TCPNGTCIGFQLVCD--GQPDCGRPGQVGPSPEEQGCGAWGPWSPWGP 1705
Score = 30.0 bits (66), Expect = 2.2
Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 17/109 (15%)
Query: 117 EGPP---GAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGP- 172
EGP G P G GL P +G +G +LV G QP G+V GP
Sbjct: 1635 EGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDG-QPDCGRPGQV-----GPS 1688
Query: 173 -----CGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGP 216
CGA+ P S C PWG S G +C GP
Sbjct: 1689 PEEQGCGAWGPWSPWG--PCSRTCGPWGQGRSRRCSPLGLLVLQNCPGP 1735
Score = 29.6 bits (65), Expect = 2.9
Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 18/87 (20%)
Query: 167 SFRLGPCGAY-FRCQNGRCIPSSLVC--------DPWGMDN-----CGDGSDQGSWSPAD 212
S+ L P A CQN C+ SLVC PW + CG G+ +
Sbjct: 4733 SWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTME---RHRT 4789
Query: 213 CR-GPSPVPSQTGSTDAHTSRSLTPSP 238
C GP P Q T+ +L P P
Sbjct: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP 4816
>gi|61744471 low density lipoprotein receptor-related protein 8
isoform 1 precursor [Homo sapiens]
Length = 963
Score = 37.0 bits (84), Expect = 0.018
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGP 216
F+C N C+ + VCD G D+CGDGSD+ + C GP
Sbjct: 172 FQCGNRSCLAAVFVCD--GDDDCGDGSDERGCADPAC-GP 208
Score = 32.3 bits (72), Expect = 0.45
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C NG CI CD G + C DGSD+ S A C
Sbjct: 91 FTCDNGHCIHERWKCD--GEEECPDGSDE---SEATC 122
Score = 32.0 bits (71), Expect = 0.59
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C+N RCIPS CD D+C D SD+ C
Sbjct: 52 FQCRNERCIPSVWRCDE--DDDCLDHSDEDDCPKKTC 86
>gi|65301119 low density lipoprotein receptor-related protein 8
isoform 4 precursor [Homo sapiens]
Length = 904
Score = 37.0 bits (84), Expect = 0.018
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGP 216
F+C N C+ + VCD G D+CGDGSD+ + C GP
Sbjct: 172 FQCGNRSCLAAVFVCD--GDDDCGDGSDERGCADPAC-GP 208
Score = 32.3 bits (72), Expect = 0.45
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F C NG CI CD G + C DGSD+ S A C
Sbjct: 91 FTCDNGHCIHERWKCD--GEEECPDGSDE---SEATC 122
Score = 32.0 bits (71), Expect = 0.59
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADC 213
F+C+N RCIPS CD D+C D SD+ C
Sbjct: 52 FQCRNERCIPSVWRCDE--DDDCLDHSDEDDCPKKTC 86
>gi|4557391 complement component 8, beta polypeptide preproprotein
[Homo sapiens]
Length = 591
Score = 36.6 bits (83), Expect = 0.024
Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 13/49 (26%)
Query: 172 PCGAYFRC------QNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCR 214
PCG+ RC Q GRC+ L+C+ G ++CGD SD+ A+CR
Sbjct: 115 PCGSQVRCEGFVCAQTGRCVNRRLLCN--GDNDCGDQSDE-----ANCR 156
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 36.2 bits (82), Expect = 0.031
Identities = 35/140 (25%), Positives = 49/140 (35%), Gaps = 11/140 (7%)
Query: 112 YLQFYEGPPGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRL- 170
Y++ YE L CG P + SS L + T F +F
Sbjct: 358 YVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNAT 417
Query: 171 -GPCG-AYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDA 228
PCG + CQ G C +CD W +C DGSD +C GP P +
Sbjct: 418 ENPCGPSELSCQAGGCKGVQWMCDMW--RDCTDGSDD------NCSGPLFPPPELACEPV 469
Query: 229 HTSRSLTPSPALGSAGSLWI 248
L S + ++W+
Sbjct: 470 QVEMCLGLSYNTTAFPNIWV 489
Score = 30.8 bits (68), Expect = 1.3
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 2/33 (6%)
Query: 177 FRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWS 209
FRC C+ VCD G NC DGSD+ + S
Sbjct: 265 FRCDQLICLLPDSVCD--GFANCADGSDETNCS 295
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 35.8 bits (81), Expect = 0.041
Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 178 RCQNGRCI-PSSLVCDP-WGMDNCGDGSDQGSWSP 210
+C +GRCI P++ C+P WG NC D W P
Sbjct: 112 KCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGP 146
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 35.8 bits (81), Expect = 0.041
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 9/87 (10%)
Query: 65 GLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALN-----TSSPAPADPCAPGSYLQFY--E 117
G+ + APG + + L P PP +P PA P + + +
Sbjct: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856
Query: 118 GPPGAPRPLGSPLCGLNIPVPVASSGP 144
GPPG P P G P G +IP P GP
Sbjct: 857 GPPGPPGPRGPP--GPSIPGPPGPRGP 881
Score = 29.3 bits (64), Expect = 3.8
Identities = 17/43 (39%), Positives = 18/43 (41%), Gaps = 6/43 (13%)
Query: 91 PAPPALN--TSSPAPADPCAPGSYLQ----FYEGPPGAPRPLG 127
P PP P P PGS+L F GPPG P P G
Sbjct: 873 PGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,849,403
Number of Sequences: 37866
Number of extensions: 879812
Number of successful extensions: 5672
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 4781
Number of HSP's gapped (non-prelim): 1057
length of query: 272
length of database: 18,247,518
effective HSP length: 101
effective length of query: 171
effective length of database: 14,423,052
effective search space: 2466341892
effective search space used: 2466341892
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.