Guide to the Human Genome
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Name: SORL1 Sequence: fasta or formatted (2214aa) NCBI GI: 4507157
Description:

sortilin-related receptor containing LDLR class A repeats preproprotein

Referenced in:

Additional Brain Proteins
Epidermal Growth Factor
Lipoproteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9        131           2
 C cysteine            4.4         97           1
 D aspartate           7.2        159           2
 E glutamate           5.7        127           2
 F phenylalanine       4.2         92           2
 G glycine             6.5        143           2
 H histidine           2.5         56           1
 I isoleucine          4.7        104           2
 K lysine              4.6        101           2
 L leucine             8.1        179           3
 M methionine          1.6         36           1
 N asparagine          5.0        110           2
 P proline             4.7        105           3
 Q glutamine           3.5         78           2
 R arginine            5.2        115           2
 S serine              8.8        195           3
 T threonine           5.6        123           2
 V valine              6.1        136           3
 W tryptophan          2.0         44           2
 Y tyrosine            3.7         83           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sortilin-related receptor containing LDLR class A rep... 
LRP1                  0.100   low density lipoprotein-related protein 1 
LRP2                  0.098   low density lipoprotein-related protein 2 
LRP1B                 0.088   low density lipoprotein-related protein 1B precursor...
LRP4                  0.054   low density lipoprotein receptor-related protein 4 ...
SORCS2                0.051   VPS10 domain receptor protein SORCS 2 
SORCS3                0.051   VPS10 domain receptor protein SORCS 3 
SORCS1                0.050   SORCS receptor 1 isoform b 
SORCS1                0.050   SORCS receptor 1 isoform a 
VLDLR                 0.049   very low density lipoprotein receptor isoform b [Hom...
VLDLR                 0.049   very low density lipoprotein receptor isoform a [Hom...
SORT1                 0.049   sortilin 1 preproprotein 
LDLR                  0.044   low density lipoprotein receptor precursor 
LRP8                  0.043   low density lipoprotein receptor-related protein 8 i...
LRP8                  0.043   low density lipoprotein receptor-related protein 8 i...
CORIN                 0.043   corin 
LRP6                  0.039   low density lipoprotein receptor-related protein 6 ...
LRP5                  0.038   low density lipoprotein receptor-related protein 5 ...
SSPO                  0.035   SCO-spondin 
LRP8                  0.031   low density lipoprotein receptor-related protein 8 i...
LRP8                  0.031   low density lipoprotein receptor-related protein 8 i...
ST14                  0.023   matriptase 
HSPG2                 0.022   heparan sulfate proteoglycan 2 
NID2                  0.021   nidogen 2 precursor 
LRP12                 0.021   low density lipoprotein-related protein 12 isoform ...
LRP12                 0.021   low density lipoprotein-related protein 12 isoform a ...
EGF                   0.021   epidermal growth factor (beta-urogastrone) 
LRP5L                 0.021   low density lipoprotein receptor-related protein 5-l...
LRP5L                 0.021   low density lipoprotein receptor-related protein 5-...
LRP3                  0.021   low density lipoprotein receptor-related protein 3 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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