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Search of human proteins with 224451128
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
(3144 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 6657 0.0
gi|38093661 eyes shut homolog isoform 3 [Homo sapiens] 1292 0.0
gi|224451131 eyes shut homolog isoform 2 [Homo sapiens] 1290 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 623 e-178
gi|24041035 notch 2 preproprotein [Homo sapiens] 613 e-175
gi|134244285 Notch homolog 3 [Homo sapiens] 563 e-159
gi|55770876 notch4 preproprotein [Homo sapiens] 485 e-136
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 405 e-112
gi|4557679 jagged 1 precursor [Homo sapiens] 398 e-110
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 377 e-103
gi|122937283 6720455I24Rik homolog [Homo sapiens] 337 8e-92
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 336 2e-91
gi|112420992 crumbs homolog 2 [Homo sapiens] 274 1e-72
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 259 2e-68
gi|66346695 fibrillin 2 precursor [Homo sapiens] 250 1e-65
gi|24430141 fibrillin 1 precursor [Homo sapiens] 249 3e-65
gi|56237021 fibrillin 3 precursor [Homo sapiens] 246 3e-64
gi|148886654 polydom [Homo sapiens] 235 6e-61
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 228 7e-59
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 227 1e-58
gi|110735443 delta-like 1 [Homo sapiens] 222 5e-57
gi|54873613 agrin [Homo sapiens] 201 9e-51
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 194 9e-49
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 184 2e-45
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 178 7e-44
gi|4759146 slit homolog 2 [Homo sapiens] 175 6e-43
gi|11321571 slit homolog 3 [Homo sapiens] 175 7e-43
gi|126091152 cubilin [Homo sapiens] 169 3e-41
gi|188528675 slit homolog 1 [Homo sapiens] 169 4e-41
gi|4557733 latent transforming growth factor beta binding protei... 168 7e-41
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 6657 bits (17272), Expect = 0.0
Identities = 3144/3144 (100%), Positives = 3144/3144 (100%)
Query: 1 MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL 60
MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL
Sbjct: 1 MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL 60
Query: 61 GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT 120
GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT
Sbjct: 61 GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT 120
Query: 121 EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS 180
EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS
Sbjct: 121 EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS 180
Query: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY 240
EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY
Sbjct: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY 240
Query: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS 300
ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS
Sbjct: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS 300
Query: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP 360
LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP
Sbjct: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP 360
Query: 361 IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL 420
IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL
Sbjct: 361 IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL 420
Query: 421 NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV 480
NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV
Sbjct: 421 NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV 480
Query: 481 WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS 540
WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS
Sbjct: 481 WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS 540
Query: 541 CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRL 600
CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRL
Sbjct: 541 CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRL 600
Query: 601 CVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTH 660
CVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTH
Sbjct: 601 CVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTH 660
Query: 661 LRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL 720
LRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL
Sbjct: 661 LRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL 720
Query: 721 CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPC 780
CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPC
Sbjct: 721 CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPC 780
Query: 781 KNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPL 840
KNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPL
Sbjct: 781 KNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPL 840
Query: 841 YTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQ 900
YTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQ
Sbjct: 841 YTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQ 900
Query: 901 DYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHG 960
DYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHG
Sbjct: 901 DYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHG 960
Query: 961 PFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCI 1020
PFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCI
Sbjct: 961 PFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCI 1020
Query: 1021 DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKI 1080
DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKI
Sbjct: 1021 DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKI 1080
Query: 1081 NDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDG 1140
NDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDG
Sbjct: 1081 NDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDG 1140
Query: 1141 PGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL 1200
PGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL
Sbjct: 1141 PGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL 1200
Query: 1201 ECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQT 1260
ECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQT
Sbjct: 1201 ECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQT 1260
Query: 1261 YTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLE 1320
YTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLE
Sbjct: 1261 YTIPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLE 1320
Query: 1321 SYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATL 1380
SYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATL
Sbjct: 1321 SYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAATL 1380
Query: 1381 GFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNR 1440
GFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNR
Sbjct: 1381 GFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADIELNR 1440
Query: 1441 QSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVI 1500
QSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVI
Sbjct: 1441 QSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPIFPAKVI 1500
Query: 1501 ISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCS 1560
ISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCS
Sbjct: 1501 ISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLRELSQTCATCS 1560
Query: 1561 MTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPS 1620
MTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPS
Sbjct: 1561 MTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHSFSSATEITPS 1620
Query: 1621 VAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMN 1680
VAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMN
Sbjct: 1621 VAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSIVPSQTISSDLMN 1680
Query: 1681 SDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPS 1740
SDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPS
Sbjct: 1681 SDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDMEKSKGSHTLFKLHPS 1740
Query: 1741 DSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATP 1800
DSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATP
Sbjct: 1741 DSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDFSEVTTNVAFYTVSATP 1800
Query: 1801 ALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPF 1860
ALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPF
Sbjct: 1801 ALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWELQPSVQYQEFPTASRHLPF 1860
Query: 1861 TRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLL 1920
TRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLL
Sbjct: 1861 TRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVALNPQNNISLEFQTFSSYGLL 1920
Query: 1921 LYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELD 1980
LYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELD
Sbjct: 1921 LYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKSINTTVRVDNGQKYTLLIRQELD 1980
Query: 1981 PCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEV 2040
PCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEV
Sbjct: 1981 PCNAELTILGRNTQICESINHVLGKPLPKSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEV 2040
Query: 2041 IEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAP 2100
IEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAP
Sbjct: 2041 IEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAP 2100
Query: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPF 2160
SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPF
Sbjct: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPF 2160
Query: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQ 2220
LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQ
Sbjct: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQ 2220
Query: 2221 NILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAY 2280
NILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAY
Sbjct: 2221 NILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAY 2280
Query: 2281 FESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCA 2340
FESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCA
Sbjct: 2281 FESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCA 2340
Query: 2341 HHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPY 2400
HHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPY
Sbjct: 2341 HHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPY 2400
Query: 2401 GRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNN 2460
GRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNN
Sbjct: 2401 GRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNN 2460
Query: 2461 LIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFF 2520
LIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFF
Sbjct: 2461 LIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFF 2520
Query: 2521 QEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTL 2580
QEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTL
Sbjct: 2521 QEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTL 2580
Query: 2581 QVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGW 2640
QVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGW
Sbjct: 2581 QVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGW 2640
Query: 2641 KGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFR 2700
KGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFR
Sbjct: 2641 KGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFR 2700
Query: 2701 SNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLR 2760
SNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLR
Sbjct: 2701 SNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLR 2760
Query: 2761 YNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTD 2820
YNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTD
Sbjct: 2761 YNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTD 2820
Query: 2821 FYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACG 2880
FYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACG
Sbjct: 2821 FYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACG 2880
Query: 2881 YNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCT 2940
YNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCT
Sbjct: 2881 YNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCT 2940
Query: 2941 LGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGI 3000
LGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGI
Sbjct: 2941 LGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGI 3000
Query: 3001 AQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYI 3060
AQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYI
Sbjct: 3001 AQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYI 3060
Query: 3061 NNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQE 3120
NNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQE
Sbjct: 3061 NNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQE 3120
Query: 3121 PKNIELIKLEGYNVYDGDEQNEVT 3144
PKNIELIKLEGYNVYDGDEQNEVT
Sbjct: 3121 PKNIELIKLEGYNVYDGDEQNEVT 3144
>gi|38093661 eyes shut homolog isoform 3 [Homo sapiens]
Length = 594
Score = 1292 bits (3344), Expect = 0.0
Identities = 590/592 (99%), Positives = 590/592 (99%)
Query: 1 MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL 60
MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL
Sbjct: 1 MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL 60
Query: 61 GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT 120
GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT
Sbjct: 61 GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT 120
Query: 121 EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS 180
EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS
Sbjct: 121 EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS 180
Query: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY 240
EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY
Sbjct: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY 240
Query: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS 300
ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS
Sbjct: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS 300
Query: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP 360
LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP
Sbjct: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP 360
Query: 361 IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL 420
IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL
Sbjct: 361 IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL 420
Query: 421 NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV 480
NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV
Sbjct: 421 NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV 480
Query: 481 WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS 540
WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS
Sbjct: 481 WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS 540
Query: 541 CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSC 592
CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR C
Sbjct: 541 CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRYLC 592
Score = 145 bits (366), Expect = 6e-34
Identities = 121/462 (26%), Positives = 179/462 (38%), Gaps = 85/462 (18%)
Query: 767 FCEQESNECKMNPCKNNSTCTD--LYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLC 824
FC QES + C + C K+Y C C ++G+ C +E++ C PC N G C
Sbjct: 173 FC-QESLSSEF--CSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDACSFKPCKNNGSC 228
Query: 825 ---HESTIPGQFVCLCPPLYTGQFCHQRYNLCD---LLHNPCRNNSTCLALVDANQH-CI 877
E+ + C+C P +TG+ C + C H C N + +N C
Sbjct: 229 INKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSN-------ITSNSFICE 281
Query: 878 CREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
C E+F G CE+ K C+ L G C + + + C G S E +++E S PC
Sbjct: 282 CDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPC 341
Query: 938 KNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYT 997
+N C+ ++N C C P + C+ C+ P + C Y C C G+T
Sbjct: 342 QNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFT 401
Query: 998 GINCEINLDEC--LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR 1055
NCE +D C LS CL++ C + I + C G C NPC +
Sbjct: 402 EKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG------------CTKNPCWFLK 449
Query: 1056 CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQ-KSAHGFTCICPRGYTGA-- 1112
LI+++ C C G CQ K F + G+ G+
Sbjct: 450 NVYLIHQHLCYCGV-------------------TFHGICQDKGPAQFEYVWQLGFAGSEG 490
Query: 1113 -YCEKSID-------NCAE-------PELNS-----------VICLNGGICV-DGPGHTF 1145
C+ ID NC E PE N+ IC NG C+ + +
Sbjct: 491 EKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEY 550
Query: 1146 DCRCLPGFSGQFCEININECSSSPCLHGADCEDHIN--GYVC 1185
C ++G N + + C H A C+D IN Y+C
Sbjct: 551 RYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRYLC 592
Score = 140 bits (352), Expect = 3e-32
Identities = 85/297 (28%), Positives = 129/297 (43%), Gaps = 36/297 (12%)
Query: 669 CVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGI 728
C P F G C+ ++D C+ PCKN +CI++ N+ Q + C+C+P + G
Sbjct: 202 CQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQA---------YECVCHPPFTGK 251
Query: 729 RCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTD 788
C + I C + C H + S+ C C + G FCE + C C +
Sbjct: 252 NCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPN 311
Query: 789 LYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQ 848
+Y EC G + QN +++E PC NG C + I +C+C P++T C
Sbjct: 312 SSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMCICSPIFTDLLCKS 369
Query: 849 RYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLS--CQDYGDCE 906
C+ P RNN+TC + + C C F KNCE + C LS C + C
Sbjct: 370 IQTSCESF--PLRNNATC-KKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCF 426
Query: 907 DMVNNFRCICRPGFSGSLCEIEINECSSEPC---KNNGTCVDLTNRFFCNCEPEYHG 960
+++ F+ +C PG C+ PC KN V L ++ C C +HG
Sbjct: 427 NIIGRFKYVCIPG------------CTKNPCWFLKN----VYLIHQHLCYCGVTFHG 467
Score = 116 bits (290), Expect = 4e-25
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)
Query: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH-----YTCDCKSGFFGTHCETN 1042
Y+C C P ++G C+ LD C +PC ++G CI+ + Y C C F G +C
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 1043 ANDCLSNPCLHGRCTELI-NEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGF 1101
C + C HG C+ + N + C CD + C++ C S+ G C S+ +
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAY 316
Query: 1102 TCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEIN 1161
T CP+G + E + E + V C NG C+ C C P F+ C+
Sbjct: 317 TYECPKGSSSQNGETDVS-----EFSLVPCQNGTDCIKISNDVM-CICSPIFTDLLCKSI 370
Query: 1162 INECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE---CIPNSCVHELCMENEPG 1218
C S P + A C+ Y C C G++ +CE ++ + +C++E N G
Sbjct: 371 QTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIG 430
Query: 1219 S-TCLCTPG 1226
+C PG
Sbjct: 431 RFKYVCIPG 439
Score = 71.6 bits (174), Expect = 1e-11
Identities = 49/186 (26%), Positives = 79/186 (42%), Gaps = 20/186 (10%)
Query: 1053 HGRCTELI--NEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHG-----FTCIC 1105
HG+C Y C C + C+ +++ C+ PC N G C + C+C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVC 244
Query: 1106 PRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININEC 1165
+TG C + I C +P +C +G C + ++F C C FSG FCE++ C
Sbjct: 245 HPPFTGKNCSEIIGQC-QPH----VCFHGN-CSNITSNSFICECDEQFSGPFCEVSAKPC 298
Query: 1166 SSSPCLHGADCEDHINGYVCKCQPGWSGHHCE---NELECIPNSCVHEL-CMENEPGSTC 1221
S C + + Y +C G S + E +E +P C + C++ C
Sbjct: 299 VSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMC 356
Query: 1222 LCTPGF 1227
+C+P F
Sbjct: 357 ICSPIF 362
Score = 65.5 bits (158), Expect = 8e-10
Identities = 80/421 (19%), Positives = 134/421 (31%), Gaps = 121/421 (28%)
Query: 531 TKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINR--- 587
+ E C+ CLSE S+ Y C ++G Y + C++ C ++
Sbjct: 179 SSEFCSGHGKCLSEAWSKTYSCHCQPPFSGK-YCQELDACSFKPCKNNGSCINKRENWDE 237
Query: 588 --PRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHN---CNCSGLQRYERNICEI 642
C C + G+ C + C + + HG C ++ N C C +++ CE+
Sbjct: 238 QAYECVCHPPFTGKNCSEIIGQCQPH--VCFHGNCSNITSNSFICECD--EQFSGPFCEV 293
Query: 643 DTEDCKSASC-KNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPG 701
+ C S K G Y + +C G E D+ E + PC+NG CI
Sbjct: 294 SAKPCVSLLFWKRGICPNSSSAYTY-ECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISN 352
Query: 702 NYFCQCVPPF------------------------KVVDGFSCLCNPGYVGIRCEQDIDDC 737
+ C C P F K + C C G+ CE+ ID C
Sbjct: 353 DVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHC 412
Query: 738 ILNA--CEHNSTC-----------------------KDLHLSYQCVCLSD---------- 762
L + C + C K+++L +Q +C
Sbjct: 413 KLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDK 472
Query: 763 --------WEGNFCEQESNECK--------------------MNPCKNNSTC-------- 786
W+ F E +C+ +P NNS+C
Sbjct: 473 GPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK 532
Query: 787 -----------TDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVC 835
+ + YR C W G E + + C + +C + +++C
Sbjct: 533 EICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRYLC 592
Query: 836 L 836
+
Sbjct: 593 I 593
Score = 65.5 bits (158), Expect = 8e-10
Identities = 79/374 (21%), Positives = 120/374 (32%), Gaps = 56/374 (14%)
Query: 535 CANGCSCLSEE---DSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCS 591
C N SC+++ D Q Y +C + G E Q + C H N C
Sbjct: 222 CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICE 281
Query: 592 CSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSAS 651
C + G C V+ C+ + G+C S + E D +
Sbjct: 282 CDEQFSGPFCEVSAKPCV-SLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP 340
Query: 652 CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPF 711
C+NGT + C P F C+ C S P +N ATC +Y C C+ F
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 712 KVVDGFSCLCNPGYVGIRCEQD--------------IDDCILNACEHNSTCKDLHLSYQC 757
+ + + + I C + I C N C K+++L +Q
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWF---LKNVYLIHQH 457
Query: 758 VCLSD------------------WEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTS 799
+C W+ F E +C+ D Y CT
Sbjct: 458 LCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQ--------GVIDAYFFLAANCTE 509
Query: 800 GWTGQNCSEEIN-------ECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNL 852
T N E+ N E + C NG C ++ LC + G + N
Sbjct: 510 DATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLE--NT 567
Query: 853 CDLLHNPCRNNSTC 866
D N C++ + C
Sbjct: 568 TDDQENECQHEAVC 581
Score = 62.0 bits (149), Expect = 9e-09
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 1088 CMNEGFCQKSAHG--FTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH-- 1143
C G C A ++C C ++G YC++ +D C+ C N G C++ +
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKP-----CKNNGSCINKRENWD 236
Query: 1144 --TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE 1197
++C C P F+G+ C I +C C HG N ++C+C +SG CE
Sbjct: 237 EQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 2339 CAHHLCRNNGTCISDNEN-----LFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSG 2391
C+ C+NNG+CI+ EN C C ++GK C C+ + C +G C +
Sbjct: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHG-NCSNITS 275
Query: 2392 TDIVCLCPYGRSGPLC 2407
+C C SGP C
Sbjct: 276 NSFICECDEQFSGPFC 291
Score = 43.9 bits (102), Expect = 0.003
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 2878 ACGYNTCRNGGEC-----TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
AC + C+N G C + + C C P + G C++ + C ++C H + C
Sbjct: 216 ACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGN-CSNIT 274
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
S S+ C C + G +CE
Sbjct: 275 SNSFICECDEQFSGPFCE 292
Score = 43.5 bits (101), Expect = 0.003
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 2344 CRNNGTCISD--NENLFCECPRLYSGKLCQ-FASCENNPCGNGATCVPK----SGTDIVC 2396
C +G C+S+ ++ C C +SGK CQ +C PC N +C+ K C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 2397 LCPYGRSGPLCTDAINITQP 2416
+C +G C++ I QP
Sbjct: 243 VCHPPFTGKNCSEIIGQCQP 262
Score = 43.5 bits (101), Expect = 0.003
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
Query: 2607 GQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGA 2666
G+ S SL+ C NG CI+ V C C+ + C ++C+ A
Sbjct: 329 GETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCE-----SFPLRNNA 383
Query: 2667 TCISLPHGYTCFCPLGTTGIYCEQAL 2692
TC Y C C G T CE+A+
Sbjct: 384 TCKKCEKDYPCSCISGFTEKNCEKAI 409
Score = 43.1 bits (100), Expect = 0.004
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C+N CI + ++ C C +++ LC+ SCE+ P N ATC K D C C G
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATC-KKCEKDYPCSCISG 399
Query: 2402 RSGPLCTDAIN 2412
+ C AI+
Sbjct: 400 FTEKNCEKAID 410
Score = 39.7 bits (91), Expect = 0.048
Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 22/98 (22%)
Query: 2609 CHASP------------CSLMKCGNGGTCIESGTS-----VYCNCTTGWKGSFCTETVST 2651
CH P CS C N G+CI + C C + G C+E +
Sbjct: 200 CHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQ 259
Query: 2652 CDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C PH C G + + C C +G +CE
Sbjct: 260 CQ-----PHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
Score = 38.5 bits (88), Expect = 0.11
Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 6/71 (8%)
Query: 2884 CRNGGECTVNG--TTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQ----SFSYSC 2937
C G+C T+SC C P ++G C + +C C + CI + +Y C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 2938 LCTLGWVGRYC 2948
+C + G+ C
Sbjct: 243 VCHPPFTGKNC 253
Score = 35.0 bits (79), Expect = 1.2
Identities = 30/125 (24%), Positives = 45/125 (36%), Gaps = 49/125 (39%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLF-CECPRLYSGKLCQFAS------------ 2374
GKN + C H+C + G C + N F CEC +SG C+ ++
Sbjct: 250 GKNCSEI-IGQCQPHVCFH-GNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRG 307
Query: 2375 -CENN---------------------------PCGNGATCVPKSGTDIVCLCPYGRSGPL 2406
C N+ PC NG C+ K D++C+C P+
Sbjct: 308 ICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCI-KISNDVMCIC-----SPI 361
Query: 2407 CTDAI 2411
TD +
Sbjct: 362 FTDLL 366
Score = 33.5 bits (75), Expect = 3.4
Identities = 21/101 (20%), Positives = 33/101 (32%)
Query: 2849 RQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN 2908
R + N+ E S G+ D + C+NG +C C C P +
Sbjct: 306 RGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDL 365
Query: 2909 TCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
C + + L + Y C C G+ + CE
Sbjct: 366 LCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
>gi|224451131 eyes shut homolog isoform 2 [Homo sapiens]
Length = 619
Score = 1290 bits (3339), Expect = 0.0
Identities = 589/589 (100%), Positives = 589/589 (100%)
Query: 1 MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL 60
MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL
Sbjct: 1 MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWTLTENICLDFYRDCWFL 60
Query: 61 GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT 120
GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT
Sbjct: 61 GVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTT 120
Query: 121 EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS 180
EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS
Sbjct: 121 EDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSS 180
Query: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY 240
EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY
Sbjct: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAY 240
Query: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS 300
ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS
Sbjct: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS 300
Query: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP 360
LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP
Sbjct: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP 360
Query: 361 IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL 420
IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL
Sbjct: 361 IFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCL 420
Query: 421 NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV 480
NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV
Sbjct: 421 NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV 480
Query: 481 WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS 540
WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS
Sbjct: 481 WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS 540
Query: 541 CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR 589
CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR
Sbjct: 541 CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR 589
Score = 144 bits (364), Expect = 1e-33
Identities = 119/456 (26%), Positives = 176/456 (38%), Gaps = 83/456 (18%)
Query: 767 FCEQESNECKMNPCKNNSTCTD--LYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLC 824
FC QES + C + C K+Y C C ++G+ C +E++ C PC N G C
Sbjct: 173 FC-QESLSSEF--CSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDACSFKPCKNNGSC 228
Query: 825 ---HESTIPGQFVCLCPPLYTGQFCHQRYNLCD---LLHNPCRNNSTCLALVDANQH-CI 877
E+ + C+C P +TG+ C + C H C N + +N C
Sbjct: 229 INKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSN-------ITSNSFICE 281
Query: 878 CREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
C E+F G CE+ K C+ L G C + + + C G S E +++E S PC
Sbjct: 282 CDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPC 341
Query: 938 KNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYT 997
+N C+ ++N C C P + C+ C+ P + C Y C C G+T
Sbjct: 342 QNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFT 401
Query: 998 GINCEINLDEC--LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR 1055
NCE +D C LS CL++ C + I + C G C NPC +
Sbjct: 402 EKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG------------CTKNPCWFLK 449
Query: 1056 CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQ-KSAHGFTCICPRGYTGA-- 1112
LI+++ C C G CQ K F + G+ G+
Sbjct: 450 NVYLIHQHLCYCGV-------------------TFHGICQDKGPAQFEYVWQLGFAGSEG 490
Query: 1113 -YCEKSID-------NCAE-------PELNS-----------VICLNGGICV-DGPGHTF 1145
C+ ID NC E PE N+ IC NG C+ + +
Sbjct: 491 EKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEY 550
Query: 1146 DCRCLPGFSGQFCEININECSSSPCLHGADCEDHIN 1181
C ++G N + + C H A C+D IN
Sbjct: 551 RYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEIN 586
Score = 140 bits (352), Expect = 3e-32
Identities = 85/297 (28%), Positives = 129/297 (43%), Gaps = 36/297 (12%)
Query: 669 CVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGI 728
C P F G C+ ++D C+ PCKN +CI++ N+ Q + C+C+P + G
Sbjct: 202 CQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQA---------YECVCHPPFTGK 251
Query: 729 RCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTD 788
C + I C + C H + S+ C C + G FCE + C C +
Sbjct: 252 NCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPN 311
Query: 789 LYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQ 848
+Y EC G + QN +++E PC NG C + I +C+C P++T C
Sbjct: 312 SSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMCICSPIFTDLLCKS 369
Query: 849 RYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLS--CQDYGDCE 906
C+ P RNN+TC + + C C F KNCE + C LS C + C
Sbjct: 370 IQTSCESF--PLRNNATC-KKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCF 426
Query: 907 DMVNNFRCICRPGFSGSLCEIEINECSSEPC---KNNGTCVDLTNRFFCNCEPEYHG 960
+++ F+ +C PG C+ PC KN V L ++ C C +HG
Sbjct: 427 NIIGRFKYVCIPG------------CTKNPCWFLKN----VYLIHQHLCYCGVTFHG 467
Score = 116 bits (290), Expect = 4e-25
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 17/249 (6%)
Query: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH-----YTCDCKSGFFGTHCETN 1042
Y+C C P ++G C+ LD C +PC ++G CI+ + Y C C F G +C
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 1043 ANDCLSNPCLHGRCTELI-NEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGF 1101
C + C HG C+ + N + C CD + C++ C S+ G C S+ +
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAY 316
Query: 1102 TCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEIN 1161
T CP+G + E + E + V C NG C+ C C P F+ C+
Sbjct: 317 TYECPKGSSSQNGETDVS-----EFSLVPCQNGTDCIKISNDVM-CICSPIFTDLLCKSI 370
Query: 1162 INECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE---CIPNSCVHELCMENEPG 1218
C S P + A C+ Y C C G++ +CE ++ + +C++E N G
Sbjct: 371 QTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIG 430
Query: 1219 S-TCLCTPG 1226
+C PG
Sbjct: 431 RFKYVCIPG 439
Score = 93.2 bits (230), Expect = 4e-18
Identities = 93/415 (22%), Positives = 150/415 (36%), Gaps = 79/415 (19%)
Query: 609 LGNHSISVHGLCLA----LSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGY 664
L + S HG CL+ +++C+C + C+ + + C CKN + + R
Sbjct: 178 LSSEFCSGHGKCLSEAWSKTYSCHCQ--PPFSGKYCQ-ELDACSFKPCKNNGSCINKREN 234
Query: 665 FFRK-----CVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVP----PFKVVD 715
+ + C P F G C I +C H C +G ++ C+C PF V
Sbjct: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
Query: 716 GFSCL--------------------CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSY 755
C+ C G E D+ + L C++ + C +
Sbjct: 295 AKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDV 354
Query: 756 QCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECD- 814
C+C + C+ C+ P +NN+TC K Y C C SG+T +NC + I+ C
Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKL 414
Query: 815 -SDPCMNGGLCHESTIPGQFVCLCPPLYTGQFC---------HQRYNLCDL-LHNPCRNN 863
S C+N C I G+F +C P T C HQ C + H C++
Sbjct: 415 LSINCLNEEWCFN--IIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDK 472
Query: 864 ST------------------CLALVDANQHCI--CREEFEGKNC-EIDVKDCLFLS---- 898
C ++DA C E+ N E + C F
Sbjct: 473 GPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK 532
Query: 899 --CQDYGDC--EDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNR 949
C + C E+ +R +C ++G++ + C++ C D NR
Sbjct: 533 EICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINR 587
Score = 71.6 bits (174), Expect = 1e-11
Identities = 49/186 (26%), Positives = 79/186 (42%), Gaps = 20/186 (10%)
Query: 1053 HGRCTELI--NEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHG-----FTCIC 1105
HG+C Y C C + C+ +++ C+ PC N G C + C+C
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVC 244
Query: 1106 PRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININEC 1165
+TG C + I C +P +C +G C + ++F C C FSG FCE++ C
Sbjct: 245 HPPFTGKNCSEIIGQC-QPH----VCFHGN-CSNITSNSFICECDEQFSGPFCEVSAKPC 298
Query: 1166 SSSPCLHGADCEDHINGYVCKCQPGWSGHHCE---NELECIPNSCVHEL-CMENEPGSTC 1221
S C + + Y +C G S + E +E +P C + C++ C
Sbjct: 299 VSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMC 356
Query: 1222 LCTPGF 1227
+C+P F
Sbjct: 357 ICSPIF 362
Score = 65.5 bits (158), Expect = 8e-10
Identities = 79/374 (21%), Positives = 120/374 (32%), Gaps = 56/374 (14%)
Query: 535 CANGCSCLSEE---DSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCS 591
C N SC+++ D Q Y +C + G E Q + C H N C
Sbjct: 222 CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICE 281
Query: 592 CSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSAS 651
C + G C V+ C+ + G+C S + E D +
Sbjct: 282 CDEQFSGPFCEVSAKPCV-SLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP 340
Query: 652 CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPF 711
C+NGT + C P F C+ C S P +N ATC +Y C C+ F
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF 400
Query: 712 KVVDGFSCLCNPGYVGIRCEQD--------------IDDCILNACEHNSTCKDLHLSYQC 757
+ + + + I C + I C N C K+++L +Q
Sbjct: 401 TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWF---LKNVYLIHQH 457
Query: 758 VCLSD------------------WEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTS 799
+C W+ F E +C+ D Y CT
Sbjct: 458 LCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQ--------GVIDAYFFLAANCTE 509
Query: 800 GWTGQNCSEEIN-------ECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNL 852
T N E+ N E + C NG C ++ LC + G + N
Sbjct: 510 DATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLE--NT 567
Query: 853 CDLLHNPCRNNSTC 866
D N C++ + C
Sbjct: 568 TDDQENECQHEAVC 581
Score = 62.0 bits (149), Expect = 9e-09
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 1088 CMNEGFCQKSAHG--FTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH-- 1143
C G C A ++C C ++G YC++ +D C+ C N G C++ +
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKP-----CKNNGSCINKRENWD 236
Query: 1144 --TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE 1197
++C C P F+G+ C I +C C HG N ++C+C +SG CE
Sbjct: 237 EQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 2339 CAHHLCRNNGTCISDNEN-----LFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSG 2391
C+ C+NNG+CI+ EN C C ++GK C C+ + C +G C +
Sbjct: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHG-NCSNITS 275
Query: 2392 TDIVCLCPYGRSGPLC 2407
+C C SGP C
Sbjct: 276 NSFICECDEQFSGPFC 291
Score = 43.9 bits (102), Expect = 0.003
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 2878 ACGYNTCRNGGEC-----TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
AC + C+N G C + + C C P + G C++ + C ++C H + C
Sbjct: 216 ACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGN-CSNIT 274
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
S S+ C C + G +CE
Sbjct: 275 SNSFICECDEQFSGPFCE 292
Score = 43.5 bits (101), Expect = 0.003
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 2344 CRNNGTCISD--NENLFCECPRLYSGKLCQ-FASCENNPCGNGATCVPK----SGTDIVC 2396
C +G C+S+ ++ C C +SGK CQ +C PC N +C+ K C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 2397 LCPYGRSGPLCTDAINITQP 2416
+C +G C++ I QP
Sbjct: 243 VCHPPFTGKNCSEIIGQCQP 262
Score = 43.5 bits (101), Expect = 0.003
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
Query: 2607 GQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGA 2666
G+ S SL+ C NG CI+ V C C+ + C ++C+ A
Sbjct: 329 GETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCE-----SFPLRNNA 383
Query: 2667 TCISLPHGYTCFCPLGTTGIYCEQAL 2692
TC Y C C G T CE+A+
Sbjct: 384 TCKKCEKDYPCSCISGFTEKNCEKAI 409
Score = 43.1 bits (100), Expect = 0.004
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C+N CI + ++ C C +++ LC+ SCE+ P N ATC K D C C G
Sbjct: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATC-KKCEKDYPCSCISG 399
Query: 2402 RSGPLCTDAIN 2412
+ C AI+
Sbjct: 400 FTEKNCEKAID 410
Score = 39.7 bits (91), Expect = 0.048
Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 22/98 (22%)
Query: 2609 CHASP------------CSLMKCGNGGTCIESGTS-----VYCNCTTGWKGSFCTETVST 2651
CH P CS C N G+CI + C C + G C+E +
Sbjct: 200 CHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQ 259
Query: 2652 CDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C PH C G + + C C +G +CE
Sbjct: 260 CQ-----PHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
Score = 38.5 bits (88), Expect = 0.11
Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 6/71 (8%)
Query: 2884 CRNGGECTVNG--TTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQ----SFSYSC 2937
C G+C T+SC C P ++G C + +C C + CI + +Y C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 2938 LCTLGWVGRYC 2948
+C + G+ C
Sbjct: 243 VCHPPFTGKNC 253
Score = 35.0 bits (79), Expect = 1.2
Identities = 30/125 (24%), Positives = 45/125 (36%), Gaps = 49/125 (39%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLF-CECPRLYSGKLCQFAS------------ 2374
GKN + C H+C + G C + N F CEC +SG C+ ++
Sbjct: 250 GKNCSEI-IGQCQPHVCFH-GNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRG 307
Query: 2375 -CENN---------------------------PCGNGATCVPKSGTDIVCLCPYGRSGPL 2406
C N+ PC NG C+ K D++C+C P+
Sbjct: 308 ICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCI-KISNDVMCIC-----SPI 361
Query: 2407 CTDAI 2411
TD +
Sbjct: 362 FTDLL 366
Score = 33.5 bits (75), Expect = 3.4
Identities = 21/101 (20%), Positives = 33/101 (32%)
Query: 2849 RQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN 2908
R + N+ E S G+ D + C+NG +C C C P +
Sbjct: 306 RGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDL 365
Query: 2909 TCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
C + + L + Y C C G+ + CE
Sbjct: 366 LCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 623 bits (1607), Expect = e-178
Identities = 373/1242 (30%), Positives = 541/1242 (43%), Gaps = 194/1242 (15%)
Query: 177 SLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSC--INKREN 234
S E C GKC EA + T +C C F G CQ+ + C PCKN G+C +++R
Sbjct: 25 SQPGETCLNGGKC--EAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGV 82
Query: 235 WDEQAYECVCHPPFTGKNC-SEIIGQCQPHVCFH-GNCSNITSNSFICECDEQFSGPFCE 292
D Y C C F+G C + + C + C + G C +T + C C +SG C+
Sbjct: 83 AD---YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ 139
Query: 293 VSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKI 350
A PC S G C ++Y CP DV+E P C++G C
Sbjct: 140 -QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNE 198
Query: 351 SNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKC-EKDYPCSCISGFTEKNCEKAI 409
C+C T C+ C P +N TC+ + + C+C+ GFT +NCE+ I
Sbjct: 199 VGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Query: 410 --------------------------------------DHCKLLSINCLNEEWCFNIIGR 431
D C+L+ C N C N G
Sbjct: 259 DDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGG 318
Query: 432 FKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHG----------------ICQ----- 470
+ VC+ G T C +N+ C+ G T H +C
Sbjct: 319 YNCVCVNGWTGEDC--SENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDAC 376
Query: 471 -----------DKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPED 519
D P + + +G G C +D A C +N
Sbjct: 377 ISNPCNEGSNCDTNPVNGKAICTCP-SGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435
Query: 520 NNSSCWFPHEGTK-EI---------CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTD 569
C + G + EI C N +CL + E++ +C + G NT +
Sbjct: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCL--DQIGEFQCICMPGYEGVHCEVNTDE 493
Query: 570 DQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNC 629
+ C H C D+IN +C C + G LC +VD C + CL + C
Sbjct: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDEC-ASTPCKNGAKCLDGPNTYTC 552
Query: 630 SGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHP 689
+ Y CE+D ++C C G+ + F C PG+ G CE +I+EC+S P
Sbjct: 553 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGV-ATFTCLCRPGYTGHHCETNINECSSQP 611
Query: 690 CKNGATCIDQPGNYFCQCV-----PPFKV------------------VDGFSCLCNPGYV 726
C++G TC D+ Y C C+ P ++ +DG+ C C PGY
Sbjct: 612 CRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYT 671
Query: 727 GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTC 786
G C +ID+C N C + TC+D + C C + C E NEC NPC + + C
Sbjct: 672 GSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA-C 730
Query: 787 TDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFC 846
D Y+C+C GW+G NC NEC+S+PC+NGG C + T +VC C ++G C
Sbjct: 731 RDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMT--SGYVCTCREGFSGPNC 788
Query: 847 HQRYNLCDLLHNPCRNNSTCLALVDANQ-------------------------------- 874
N C NPC N TC+ V +
Sbjct: 789 QTNINEC--ASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ 846
Query: 875 -------HCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEI 927
C+C ++G+ CE+D+ +C+ C+ C++ +RC C+ G+SG CE
Sbjct: 847 SEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCET 906
Query: 928 EINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG 987
+I++C PC N G+C D N FC+C P + G FCE D+N+C PC + NC D
Sbjct: 907 DIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDS 966
Query: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCL 1047
Y C C G++GI+CE N +C C + G C+DGIN +TC C GF G++C+ + N+C
Sbjct: 967 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECD 1026
Query: 1048 SNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICP 1106
S PCLH G C + Y C+C T C+ ++ C S PC N G C ++ + C CP
Sbjct: 1027 SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP 1086
Query: 1107 RGYTGAYCEKSIDNC---AEPELNSV--ICLNGGICVDGPGHTFDCRCLPGFSGQFCEIN 1161
G+TG YC+ +C A+ + V +C +GG+CVD G+T CRC G++G +CE
Sbjct: 1087 SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDA-GNTHHCRCQAGYTGSYCEDL 1145
Query: 1162 INECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVHELCMENEPGST 1220
++ECS SPC +GA C D++ GY CKC G+ G +C E+ EC+ + C + G T
Sbjct: 1146 VDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPC--------QNGGT 1197
Query: 1221 CLCTPGFMTCSI-----GLLCGDEIRRITCLTPIFQRTDPIS 1257
CL P CS G+ C EI C P+ DP+S
Sbjct: 1198 CLDLPNTYKCSCPRGTQGVHC--EINVDDCNPPV----DPVS 1233
Score = 565 bits (1457), Expect = e-160
Identities = 361/1225 (29%), Positives = 509/1225 (41%), Gaps = 211/1225 (17%)
Query: 172 QFCQESLSS---EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKP--CKNN 225
Q C+E++ C G C+ TY+C C P ++G+YC E +D C P C+N
Sbjct: 252 QNCEENIDDCPGNNCKNGGACVDGV--NTYNCRCPPEWTGQYCTEDVDECQLMPNACQNG 309
Query: 226 GSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHG----------------- 268
G+C N Y CVC +TG++CSE I C CFHG
Sbjct: 310 GTCHNTHGG-----YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHG 364
Query: 269 ---------------------NC-SNITSNSFICECDEQFSGPFCE-------VSAKPCV 299
NC +N + IC C ++GP C + A PC
Sbjct: 365 RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCE 424
Query: 300 SLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICS 359
G C N+ ++ +C +G + E DV+E PCQN C+ + CIC
Sbjct: 425 HA-----GKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICM 479
Query: 360 PIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINC 419
P + + C+ C S P +N C ++ C C +GFT C+ +D C S C
Sbjct: 480 PGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA--STPC 537
Query: 420 LNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEY 479
N C + + VC G T C + C +G C+D G A F
Sbjct: 538 KNGAKCLDGPNTYTCVCTEGYTGTHCE-------VDIDECDPDPCHYGSCKD-GVATFTC 589
Query: 480 VWQLGFAGSE---------------GEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSC 524
+ + G+ G G CQ +AY C + T N E N C
Sbjct: 590 LCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCF---CLKGTTGPNC-EINLDDC 645
Query: 525 WFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDE 584
C +G +CL + D Y C + G+M N + N C + C+D
Sbjct: 646 ------ASSPCDSG-TCLDKIDG--YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDG 696
Query: 585 INRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDT 644
IN C C Y C+ V+ C N + VHG C + C + C+I+
Sbjct: 697 INGFTCRCPEGYHDPTCLSEVNEC--NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINN 754
Query: 645 EDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYF 704
+C+S C NG T + + C GF G C+ +I+ECAS+PC N TCID Y
Sbjct: 755 NECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814
Query: 705 CQCVPPF-----KVV---------------------DGFSCLCNPGYVGIRCEQDIDDCI 738
C C+ P+ +VV + FSC+C G+ G CE DI++C+
Sbjct: 815 CNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECV 874
Query: 739 LNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECT 798
L+ C H ++C++ H Y+C C + + G CE + ++C+ NPC N +CTD + C+C
Sbjct: 875 LSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCL 934
Query: 799 SGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHN 858
G+ G C E+INEC SDPC NG C + + C CP ++G C N D +
Sbjct: 935 PGFRGTFCEEDINECASDPCRNGANCTDCV--DSYTCTCPAGFSGIHCEN--NTPDCTES 990
Query: 859 PCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRP 918
C N TC+ +++ C+C F G C+ DV +C C G C+D ++RC C
Sbjct: 991 SCFNGGTCVDGINSFT-CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQ 1049
Query: 919 GFSGSLCEIEINECSSEPCKNNGTC----------------------------------- 943
G++G C+ ++ C S PCKN G C
Sbjct: 1050 GYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQG 1109
Query: 944 -------------VDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNC 990
VD N C C+ Y G +CE V++C SPC + C GY+C
Sbjct: 1110 VDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSC 1169
Query: 991 LCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDC---- 1046
C GY G+NC +DECLS PC + G C+D N Y C C G G HCE N +DC
Sbjct: 1170 KCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPV 1229
Query: 1047 ----LSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGF--CQKSAH 1099
S C + G C + + Y C+C +C+ +N+C S PC G C + +
Sbjct: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVN 1289
Query: 1100 GFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICV--DGPGHTFDCRCLPGFSGQF 1157
F C C G+TG CE I+ C C NGG C F C+C GF G
Sbjct: 1290 DFHCECRAGHTGRRCESVINGCKGKP-----CKNGGTCAVASNTARGFICKCPAGFEGAT 1344
Query: 1158 CEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE--NELECI-PNSCVHELCME 1214
CE + C S CL+G C C C ++G C+ C+ N C ++ E
Sbjct: 1345 CENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCE 1404
Query: 1215 ---NEPGSTCLCTPGFMTCSIGLLC 1236
P CLC F GLLC
Sbjct: 1405 PTSESPFYRCLCPAKFN----GLLC 1425
Score = 461 bits (1186), Expect = e-129
Identities = 327/1170 (27%), Positives = 474/1170 (40%), Gaps = 250/1170 (21%)
Query: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKREN 234
+ +S C +G+CL + + C C F+G CQ ++D C+ PCKN C++
Sbjct: 492 DECASSPCLHNGRCLDKI--NEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLD---- 545
Query: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
Y CVC +TG +C I +C P C +G+C + + +F C C ++G CE +
Sbjct: 546 -GPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVA-TFTCLCRPGYTGHHCETN 603
Query: 295 AKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDV 354
C S G C + +AY C KG++ N E ++ + + PC +GT C+ +
Sbjct: 604 INECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT-CLDKIDGY 662
Query: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKL 414
C C P +T +C C P N TC+ + C C G+ + C ++ C
Sbjct: 663 ECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN- 721
Query: 415 LSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGP 474
S C++ C + + +K C PG + C N + C G G C+D
Sbjct: 722 -SNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNE--CESNPCVNG----GTCKDM-T 772
Query: 475 AQFEYVWQLGFAGSEGEKCQGVIDAYFFLAAN-CTEDATYVNDPEDNNSSCWFPHEG-TK 532
+ + + GF+G CQ I+ A+N C T ++D +C P+ G T
Sbjct: 773 SGYVCTCREGFSGPN---CQTNINE---CASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
Query: 533 EI---------CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKD 583
E+ C NG C ED + + +C W G C+
Sbjct: 827 EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQ------------------TCEV 868
Query: 584 EINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEID 643
+IN C S G C + HG + C+C Y CE D
Sbjct: 869 DINE--CVLSPCRHGASCQ------------NTHG-----GYRCHCQA--GYSGRNCETD 907
Query: 644 TEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNY 703
+DC+ C NG + T F C+PGF+GT CE DI+ECAS PC+NGA C D +Y
Sbjct: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSY 967
Query: 704 FCQCVPPFK---------------------VVDG---FSCLCNPGYVGIRCEQDIDDCIL 739
C C F VDG F+CLC PG+ G C+ D+++C
Sbjct: 968 TCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDS 1027
Query: 740 NACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTS 799
C H TC+D SY+C C + G C+ + C +PCKN C + YRCEC S
Sbjct: 1028 QPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPS 1087
Query: 800 GWTGQNCSEEINECD----------SDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQR 849
GWTG C C+ + C +GGLC ++ C C YTG +C
Sbjct: 1088 GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG--NTHHCRCQAGYTGSYCEDL 1145
Query: 850 YNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMV 909
+ C +PC+N +TC + C C + G NC ++ +CL CQ+ G C D+
Sbjct: 1146 VDECS--PSPCQNGATCTDYL-GGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLP 1202
Query: 910 NNFRCICRPGFSGSLCEIEINECS--------SEPCKNNGTCVDLTNRFFCNCEPEYHGP 961
N ++C C G G CEI +++C+ S C NNGTCVD + C C P + G
Sbjct: 1203 NTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE 1262
Query: 962 FCELDVNKCKISPC--LDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPC------ 1013
CE DVN+C +PC +NCV R + ++C C G+TG CE ++ C +PC
Sbjct: 1263 RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTC 1322
Query: 1014 -----------------------------------LHDGVCIDGINHYTCDCKSGFFGTH 1038
L+ G CI G TC C F G
Sbjct: 1323 AVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPE 1382
Query: 1039 CETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA 1098
C+ A S+PCL G PC N+G C+ ++
Sbjct: 1383 CQFPA----SSPCLGGN-------------------------------PCYNQGTCEPTS 1407
Query: 1099 HG--FTCICPRGYTGAYCE----------------------KSIDNCAEPELNSVICL-- 1132
+ C+CP + G C + C E N V L
Sbjct: 1408 ESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQC 1467
Query: 1133 -------NGGIC---VDGP--GHTFDCRCLPGFSGQFCEININECSSSPCL-HGADC--- 1176
+GG C + P T +C FS C+ ++C+S+ CL G DC
Sbjct: 1468 NNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCD---SQCNSAGCLFDGFDCQRA 1524
Query: 1177 EDHING-YVCKCQPGWSGHHCE---NELEC 1202
E N Y C+ +S HC+ N EC
Sbjct: 1525 EGQCNPLYDQYCKDHFSDGHCDQGCNSAEC 1554
Score = 73.6 bits (179), Expect = 3e-12
Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 2599 HPNAGRSVGQCHAS--PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH 2656
H AG S C C C NGG+C + + +C+C G++G+FC E ++ C
Sbjct: 894 HCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINEC--AS 951
Query: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
DP C GA C YTC CP G +GI+CE
Sbjct: 952 DP---CRNGANCTDCVDSYTCTCPAGFSGIHCE 981
Score = 70.9 bits (172), Expect = 2e-11
Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 10/84 (11%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C SPC NG TC + C C G+ G C+E + C H C G
Sbjct: 1146 VDECSPSPCQ-----NGATCTDYLGGYSCKCVAGYHGVNCSEEIDEC-----LSHPCQNG 1195
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
TC+ LP+ Y C CP GT G++CE
Sbjct: 1196 GTCLDLPNTYKCSCPRGTQGVHCE 1219
Score = 66.6 bits (161), Expect = 4e-10
Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 2596 PEGH--PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653
P+G+ PN V C +SPC NGG C ++ T C C +GW G +C +C+
Sbjct: 1048 PQGYTGPNCQNLVHWCDSSPCK-----NGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE 1102
Query: 2654 PEH-----DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
D C G C+ + + C C G TG YCE + PS
Sbjct: 1103 VAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPS 1152
Score = 65.9 bits (159), Expect = 6e-10
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
N + +C + PC NGGTC++ + C+C G +G C V C+P DP
Sbjct: 1179 NCSEEIDECLSHPCQ-----NGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVS 1233
Query: 2661 H---CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C TC+ GY+C CP G G CE
Sbjct: 1234 RSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
Score = 65.1 bits (157), Expect = 1e-09
Identities = 82/342 (23%), Positives = 124/342 (36%), Gaps = 69/342 (20%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C+ C NGGTC++ S C C G+ GS+C V+ CD + C G TC
Sbjct: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ-----PCLHGGTCQDGCG 1041
Query: 2674 GYTCFCPLGTTGIYCEQALSISDPS-FRSNELSWMSFASFHVRKKTHIQLQFQPLAADGI 2732
Y C CP G TG C+ + D S ++ W +TH Q
Sbjct: 1042 SYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCW----------QTHTQ----------- 1080
Query: 2733 LFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHI-IKAGRV 2791
Y + +G + + V+ V + D + + G+T H +AG
Sbjct: 1081 --YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
Query: 2792 GAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQV 2851
G+ Y + ++ ++ S Y+GG S + G+ G
Sbjct: 1139 GS--YCE----DLVDECSPSPCQNGATCTDYLGGYSCKCV----------AGYHG----- 1177
Query: 2852 IINNQELQLTEFGAKGGSNVGDC----DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAG 2907
+N E ++ E + N G C + C G C +N C P
Sbjct: 1178 -VNCSE-EIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDD----CNP--PV 1229
Query: 2908 NTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+ ++S C NN C+ DQ YSC C G+VG CE
Sbjct: 1230 DPVSRSPKCFNN-----GTCV-DQVGGYSCTCPPGFVGERCE 1265
Score = 64.7 bits (156), Expect = 1e-09
Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV---SCLNNLCLHQSL 2926
N+ DC G N C+NGG C T++CRC P+W G C + V + N C +
Sbjct: 257 NIDDCPG-----NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGT 311
Query: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
C + Y+C+C GW G C
Sbjct: 312 C-HNTHGGYNCVCVNGWTGEDC 332
Score = 63.5 bits (153), Expect = 3e-09
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C C NGG C++ + C C W G +CTE V C P+ C G TC +
Sbjct: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQL---MPNACQNGGTCHNTHG 317
Query: 2674 GYTCFCPLGTTGIYCEQ 2690
GY C C G TG C +
Sbjct: 318 GYNCVCVNGWTGEDCSE 334
Score = 63.5 bits (153), Expect = 3e-09
Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 25/130 (19%)
Query: 2304 GFRGCILDLQVNNKEFFIIDEARHGKNIENC-------------------HVPWCAHHLC 2344
GFRG + +N D R+G N +C + P C C
Sbjct: 936 GFRGTFCEEDINE---CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 992
Query: 2345 RNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYGR 2402
N GTC+ + C CP ++G CQ C++ PC +G TC G+ C CP G
Sbjct: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGS-YRCTCPQGY 1051
Query: 2403 SGPLCTDAIN 2412
+GP C + ++
Sbjct: 1052 TGPNCQNLVH 1061
Score = 63.2 bits (152), Expect = 4e-09
Identities = 41/128 (32%), Positives = 56/128 (43%), Gaps = 17/128 (13%)
Query: 2841 PVGFQGCIRQVIINNQELQLTEFGAKGGSNVG---------------DCDGTACGYNTCR 2885
P G+QG +V IN L GA + G + D C N C
Sbjct: 858 PTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCH 917
Query: 2886 NGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWV 2944
NGG CT T C CLP + G C + ++ C ++ C + + C D SY+C C G+
Sbjct: 918 NGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC-TDCVDSYTCTCPAGFS 976
Query: 2945 GRYCENKT 2952
G +CEN T
Sbjct: 977 GIHCENNT 984
Score = 62.8 bits (151), Expect = 5e-09
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 2878 ACGYNTCRNGGECTV-NGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYS 2936
AC N CRNGG C + T + CRC P W+G +C Q+ C +N C + C+P ++ SY
Sbjct: 105 ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEA-SYI 163
Query: 2937 CLCTLGWVGRYC 2948
C C + G C
Sbjct: 164 CHCPPSFHGPTC 175
Score = 62.0 bits (149), Expect = 9e-09
Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 2339 CAHHLCRNNGTC-ISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGTDIVC 2396
C + CRN GTC + C CP +SGK CQ A C +NPC NG C+P + +C
Sbjct: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEAS-YIC 164
Query: 2397 LCPYGRSGPLCTDAIN 2412
CP GP C +N
Sbjct: 165 HCPPSFHGPTCRQDVN 180
Score = 62.0 bits (149), Expect = 9e-09
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 6/79 (7%)
Query: 2613 PCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
PCS C NGGTC +G + C C G+ G C E + C P ++C G C+
Sbjct: 221 PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDC-----PGNNCKNGGACVDG 275
Query: 2672 PHGYTCFCPLGTTGIYCEQ 2690
+ Y C CP TG YC +
Sbjct: 276 VNTYNCRCPPEWTGQYCTE 294
Score = 60.8 bits (146), Expect = 2e-08
Identities = 30/90 (33%), Positives = 40/90 (44%), Gaps = 10/90 (11%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+C +SPC + G C++ C C TG+ G C V C C GA
Sbjct: 493 ECASSPCL-----HNGRCLDKINEFQCECPTGFTGHLCQYDVDEC-----ASTPCKNGAK 542
Query: 2668 CISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
C+ P+ YTC C G TG +CE + DP
Sbjct: 543 CLDGPNTYTCVCTEGYTGTHCEVDIDECDP 572
Score = 59.3 bits (142), Expect = 6e-08
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 2853 INNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ 2912
+N + + G G + D D + G N C + G+C +F C+CL + G C
Sbjct: 392 VNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEI 451
Query: 2913 SVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKT 2952
V+ C++N C + + C+ DQ + C+C G+ G +CE T
Sbjct: 452 DVNECVSNPCQNDATCL-DQIGEFQCICMPGYEGVHCEVNT 491
Score = 58.9 bits (141), Expect = 8e-08
Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVC 2396
CA C +NG C+ CECP ++G LCQ+ C + PC NGA C+ T C
Sbjct: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNT-YTC 552
Query: 2397 LCPYGRSGPLCTDAINITQP 2416
+C G +G C I+ P
Sbjct: 553 VCTEGYTGTHCEVDIDECDP 572
Score = 58.5 bits (140), Expect = 1e-07
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 2602 AGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH 2661
+G+S Q A PC+ C NGG C+ S C+C + G C + V+ C + P
Sbjct: 134 SGKSCQQ--ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK---PGL 188
Query: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
C G TC + Y C C TG CE+ PS
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPS 225
Score = 58.5 bits (140), Expect = 1e-07
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 2879 CGYNTCRNGGECTVNG-TTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYS 2936
C + C+NGG C G T C CLP + G C +++ C N C + C+ D +Y+
Sbjct: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACV-DGVNTYN 280
Query: 2937 CLCTLGWVGRYC 2948
C C W G+YC
Sbjct: 281 CRCPPEWTGQYC 292
Score = 58.5 bits (140), Expect = 1e-07
Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 2614 CSLMK--CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
C LM C NGGTC + C C GW G C+E + C C GATC
Sbjct: 299 CQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDC-----ASAACFHGATCHDR 353
Query: 2672 PHGYTCFCPLGTTGIYC 2688
+ C CP G TG+ C
Sbjct: 354 VASFYCECPHGRTGLLC 370
Score = 58.5 bits (140), Expect = 1e-07
Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
+ +C + PC NG C + S C C G+ G C C C G
Sbjct: 946 INECASDPCR-----NGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES-----SCFNG 995
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISD 2696
TC+ + +TC CP G TG YC+ ++ D
Sbjct: 996 GTCVDGINSFTCLCPPGFTGSYCQHDVNECD 1026
Score = 58.5 bits (140), Expect = 1e-07
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 12/83 (14%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC----------LNNLCLHQSLC 2927
C + C+NGG+C T + C C W G C+ SVSC + LC H LC
Sbjct: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
Query: 2928 IPDQSFSYSCLCTLGWVGRYCEN 2950
+ D ++ C C G+ G YCE+
Sbjct: 1123 V-DAGNTHHCRCQAGYTGSYCED 1144
Score = 58.2 bits (139), Expect = 1e-07
Identities = 33/92 (35%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 2326 RHGKNIENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCG 2381
R G + NC ++ CA + C N GTCI D C C Y+G C+ A C +PC
Sbjct: 780 REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCR 839
Query: 2382 NGATCVPKSGTD-IVCLCPYGRSGPLCTDAIN 2412
NG C + C+CP G G C IN
Sbjct: 840 NGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871
Score = 57.8 bits (138), Expect = 2e-07
Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 10/84 (11%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C + PC +GGTC + S C C G+ G C V CD C G
Sbjct: 1022 VNECDSQPCL-----HGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSS-----PCKNG 1071
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
C Y C CP G TG+YC+
Sbjct: 1072 GKCWQTHTQYRCECPSGWTGLYCD 1095
Score = 57.4 bits (137), Expect = 2e-07
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 2612 SPCSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCI 2669
+PC+ C NGG C +S S C C TGW+G C ++ C C GA+C
Sbjct: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP-----CRHGASCQ 885
Query: 2670 SLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
+ GY C C G +G CE + P+
Sbjct: 886 NTHGGYRCHCQAGYSGRNCETDIDDCRPN 914
Score = 57.0 bits (136), Expect = 3e-07
Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 2332 ENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF-ASCENNPCGNGATC-- 2386
E+C ++ CA C + TC + +CECP +G LC +C +NPC G+ C
Sbjct: 330 EDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
Query: 2387 VPKSGTDIVCLCPYGRSGPLCTDAIN 2412
P +G +C CP G +GP C+ ++
Sbjct: 390 NPVNG-KAICTCPSGYTGPACSQDVD 414
Score = 57.0 bits (136), Expect = 3e-07
Identities = 32/116 (27%), Positives = 41/116 (35%), Gaps = 36/116 (31%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH------ 2661
Q C+ C NG C++ + C CT G+ G+ C + CDP DP H+
Sbjct: 526 QYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP--DPCHYGSCKDG 583
Query: 2662 ----------------------------CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G TC + Y CFC GTTG CE
Sbjct: 584 VATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCE 639
Score = 57.0 bits (136), Expect = 3e-07
Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQ 2931
D + C N C NGG C + + C C ++G C +++ C +N CL+Q CI D
Sbjct: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV 810
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
+ Y C C L + G CE
Sbjct: 811 A-GYKCNCLLPYTGATCE 827
Score = 57.0 bits (136), Expect = 3e-07
Identities = 39/128 (30%), Positives = 52/128 (40%), Gaps = 25/128 (19%)
Query: 2843 GFQGCIRQVIINNQELQLTEFGAKGGSNVGDC------------DGTACGYNT------- 2883
GF+G + IN + + G+N DC G C NT
Sbjct: 936 GFRGTFCEEDIN----ECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS 991
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
C NGG C +F+C C P + G+ C V+ C + CLH C D SY C C G
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTC-QDGCGSYRCTCPQG 1050
Query: 2943 WVGRYCEN 2950
+ G C+N
Sbjct: 1051 YTGPNCQN 1058
Score = 55.8 bits (133), Expect = 6e-07
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Query: 2879 CGYNTCRNGGEC--TVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSY 2935
C + CRNGGEC + + +FSC C W G TC ++ C+ + C H + C + Y
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASC-QNTHGGY 891
Query: 2936 SCLCTLGWVGRYCE 2949
C C G+ GR CE
Sbjct: 892 RCHCQAGYSGRNCE 905
Score = 55.5 bits (132), Expect = 8e-07
Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 13/96 (13%)
Query: 2596 PEGH--PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653
PEG+ P V +C+++PC G C +S C+C GW G+ C + C
Sbjct: 705 PEGYHDPTCLSEVNECNSNPCV------HGACRDSLNGYKCDCDPGWSGTNCDINNNEC- 757
Query: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
E +P C G TC + GY C C G +G C+
Sbjct: 758 -ESNP---CVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
Score = 55.5 bits (132), Expect = 8e-07
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 10/91 (10%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+C ++PC NGGTC + + C C G+ G C ++ C + C T
Sbjct: 756 ECESNPCV-----NGGTCKDMTSGYVCTCREGFSGPNCQTNINEC-----ASNPCLNQGT 805
Query: 2668 CISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
CI GY C C L TG CE L+ PS
Sbjct: 806 CIDDVAGYKCNCLLPYTGATCEVVLAPCAPS 836
Score = 54.3 bits (129), Expect = 2e-06
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 33/129 (25%)
Query: 2304 GFRGCILDLQVNNKEFFIIDEARHGKNIENCH-------------------VPWCAHHLC 2344
G++G ++ +N ++ RHG + +N H + C + C
Sbjct: 860 GWQGQTCEVDINE---CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPC 916
Query: 2345 RNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIV----CLC 2398
N G+C FC+C + G C+ C ++PC NGA C TD V C C
Sbjct: 917 HNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC-----TDCVDSYTCTC 971
Query: 2399 PYGRSGPLC 2407
P G SG C
Sbjct: 972 PAGFSGIHC 980
Score = 53.5 bits (127), Expect = 3e-06
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 8/81 (9%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
++ +CD C Y +C++G TF+C C P + G+ C +++ C + C H C
Sbjct: 566 DIDECDPDPCHYGSCKDGV------ATFTCLCRPGYTGHHCETNINECSSQPCRHGGTC- 618
Query: 2929 PDQSFSYSCLCTLGWVGRYCE 2949
D+ +Y C C G G CE
Sbjct: 619 QDRDNAYLCFCLKGTTGPNCE 639
Score = 52.8 bits (125), Expect = 5e-06
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 7/98 (7%)
Query: 2858 LQLTEFGAK---GGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV 2914
L LTE+ + G S C N C NGG+C ++ C C P + G TC Q V
Sbjct: 120 LTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV 179
Query: 2915 SCLN---NLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+ LC H C ++ SY C+C G CE
Sbjct: 180 NECGQKPGLCRHGGTC-HNEVGSYRCVCRATHTGPNCE 216
Score = 52.8 bits (125), Expect = 5e-06
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVP 2388
NC + CA C ++GTC+ + C C Y+G +C C NPC NG TC
Sbjct: 637 NCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTC-- 693
Query: 2389 KSGTD-IVCLCPYGRSGPLCTDAIN 2412
+ G + C CP G P C +N
Sbjct: 694 EDGINGFTCRCPEGYHDPTCLSEVN 718
Score = 52.4 bits (124), Expect = 7e-06
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
PN ++ +C ++PC N GTCI+ CNC + G+ C ++ C P
Sbjct: 786 PNCQTNINECASNPCL-----NQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC-----AP 835
Query: 2660 HHCSRGATCISLP--HGYTCFCPLGTTGIYCE 2689
C G C ++C CP G G CE
Sbjct: 836 SPCRNGGECRQSEDYESFSCVCPTGWQGQTCE 867
Score = 52.0 bits (123), Expect = 9e-06
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 11/83 (13%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
PN ++ C +SPC + GTC++ C C G+ GS C + C
Sbjct: 636 PNCEINLDDCASSPC------DSGTCLDKIDGYECACEPGYTGSMCNINIDEC-----AG 684
Query: 2660 HHCSRGATCISLPHGYTCFCPLG 2682
+ C G TC +G+TC CP G
Sbjct: 685 NPCHNGGTCEDGINGFTCRCPEG 707
Score = 52.0 bits (123), Expect = 9e-06
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 9/89 (10%)
Query: 2332 ENCHVPWCAHHL--CRNN----GTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNG 2383
E H P C + C +N G C C+C +SG C + CE+NPC NG
Sbjct: 706 EGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNG 765
Query: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
TC + + VC C G SGP C IN
Sbjct: 766 GTCKDMT-SGYVCTCREGFSGPNCQTNIN 793
Score = 52.0 bits (123), Expect = 9e-06
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSF-SYS 2936
C N C N G C + + C CL + G TC ++ C + C + C + + S+S
Sbjct: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFS 854
Query: 2937 CLCTLGWVGRYCE 2949
C+C GW G+ CE
Sbjct: 855 CVCPTGWQGQTCE 867
Score = 52.0 bits (123), Expect = 9e-06
Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 2602 AGRSVGQCHA--SPCSLMKCGNGGTC-IESGTS--VYCNCTTGWKGSFCTETVSTCDPEH 2656
AG + +C + + C C NGGTC + S T+ C C G++G+ C TC
Sbjct: 1297 AGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR 1356
Query: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G TCIS P TC C TG C+
Sbjct: 1357 -----CLNGGTCISGPRSPTCLCLGPFTGPECQ 1384
Score = 52.0 bits (123), Expect = 9e-06
Identities = 29/74 (39%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCE----NNPCGNGATCVPKSGTDI 2394
C C N GTCIS + C C ++G CQF + NPC N TC P S +
Sbjct: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPF 1411
Query: 2395 V-CLCPYGRSGPLC 2407
CLCP +G LC
Sbjct: 1412 YRCLCPAKFNGLLC 1425
Score = 51.6 bits (122), Expect = 1e-05
Identities = 30/79 (37%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 2339 CAHHLCRNNGTC-ISDNENLF---CECPRLYSGKLCQFA---SCENNPCGNGATCVPKSG 2391
C C+N GTC + D + C C +SG LC +C NPC NG TC +
Sbjct: 63 CLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTL 122
Query: 2392 TDIVCLCPYGRSGPLCTDA 2410
T+ C CP G SG C A
Sbjct: 123 TEYKCRCPPGWSGKSCQQA 141
Score = 51.6 bits (122), Expect = 1e-05
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPY 2400
LCR+ GTC ++ + C C ++G C+ + C +PC NG TC P C C
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
Query: 2401 GRSGPLCTDAIN 2412
G +G C + I+
Sbjct: 248 GFTGQNCEENID 259
Score = 51.6 bits (122), Expect = 1e-05
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
G+ N+ +C G N C NGG C F+CRC + TC V+ C +N C+
Sbjct: 672 GSMCNINIDECAG-----NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV 726
Query: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
H + D Y C C GW G C+
Sbjct: 727 HGA--CRDSLNGYKCDCDPGWSGTNCD 751
Score = 51.2 bits (121), Expect = 2e-05
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 2327 HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP------- 2379
HG N + C H C+N GTC+ C CPR G C+ + NP
Sbjct: 1176 HGVNCSE-EIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSR 1234
Query: 2380 ---CGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
C N TCV + G C CP G G C +N
Sbjct: 1235 SPKCFNNGTCVDQVG-GYSCTCPPGFVGERCEGDVN 1269
Score = 50.1 bits (118), Expect = 4e-05
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 2882 NTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCT 2940
N C+NGG C ++C C+ W G C++++ C + C H + C D+ S+ C C
Sbjct: 304 NACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC-HDRVASFYCECP 362
Query: 2941 LGWVGRYC 2948
G G C
Sbjct: 363 HGRTGLLC 370
Score = 50.1 bits (118), Expect = 4e-05
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 2339 CAHHLCRNNGT--CISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGT-- 2392
C + C GT C+ + CEC ++G+ C+ C+ PC NG TC S T
Sbjct: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTAR 1330
Query: 2393 DIVCLCPYGRSGPLC 2407
+C CP G G C
Sbjct: 1331 GFICKCPAGFEGATC 1345
Score = 50.1 bits (118), Expect = 4e-05
Identities = 34/111 (30%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Query: 2843 GFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTT---FSC 2899
G Q C+++V + E + G + S + C G C+NGG C V T F C
Sbjct: 1280 GTQNCVQRVNDFHCECRAGHTGRRCESVINGCKG-----KPCKNGGTCAVASNTARGFIC 1334
Query: 2900 RCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+C + G TC N + +C + CL+ CI S +CLC + G C+
Sbjct: 1335 KCPAGFEGATCENDARTCGSLRCLNGGTCISGPR-SPTCLCLGPFTGPECQ 1384
Score = 49.3 bits (116), Expect = 6e-05
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C + C + G C F C C + G+ C V C + C + + C+ D +Y+C
Sbjct: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCL-DGPNTYTC 552
Query: 2938 LCTLGWVGRYCE 2949
+CT G+ G +CE
Sbjct: 553 VCTEGYTGTHCE 564
Score = 49.3 bits (116), Expect = 6e-05
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 14/101 (13%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCE--------- 2376
G N +N V WC C+N G C + CECP ++G C SCE
Sbjct: 1053 GPNCQNL-VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
Query: 2377 -NNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
C +G CV +G C C G +G C D ++ P
Sbjct: 1112 VARLCQHGGLCV-DAGNTHHCRCQAGYTGSYCEDLVDECSP 1151
Score = 48.9 bits (115), Expect = 8e-05
Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATC--VPKSG-TDIVCLCP 2399
C N G C + N C C + G CQ + C + PC N TC V + G D C C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
Query: 2400 YGRSGPLCTDAIN---ITQPRFSG 2420
G SGPLC ++ +T P +G
Sbjct: 91 LGFSGPLCLTPLDNACLTNPCRNG 114
Score = 48.9 bits (115), Expect = 8e-05
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPY 2400
LC++ G C+ C C Y+G C+ C +PC NGATC G C C
Sbjct: 1115 LCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLG-GYSCKCVA 1173
Query: 2401 GRSGPLCTDAIN 2412
G G C++ I+
Sbjct: 1174 GYHGVNCSEEID 1185
Score = 48.1 bits (113), Expect = 1e-04
Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C + G CI+ + C+C + Y+G C+ C +NPC N ATC+ + G + C+C G
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIG-EFQCICMPG 481
Query: 2402 RSGPLC 2407
G C
Sbjct: 482 YEGVHC 487
Score = 47.8 bits (112), Expect = 2e-04
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 2596 PEGH--PNAGRSVGQCH--ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVST 2651
P G+ P + V +C A+PC + G CI + S C C G+ G C V+
Sbjct: 401 PSGYTGPACSQDVDECSLGANPCE-----HAGKCINTLGSFECQCLQGYTGPRCEIDVNE 455
Query: 2652 CDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C + C ATC+ + C C G G++CE
Sbjct: 456 C-----VSNPCQNDATCLDQIGEFQCICMPGYEGVHCE 488
Score = 47.4 bits (111), Expect = 2e-04
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFS 2934
D C C+NG +C T++C C + G C + + H C D +
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSC-KDGVAT 586
Query: 2935 YSCLCTLGWVGRYCE 2949
++CLC G+ G +CE
Sbjct: 587 FTCLCRPGYTGHHCE 601
Score = 46.6 bits (109), Expect = 4e-04
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+ + + CS C +GGTC + + C C G G C + C C G T
Sbjct: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDC-----ASSPCDSG-T 654
Query: 2668 CISLPHGYTCFCPLGTTGIYC 2688
C+ GY C C G TG C
Sbjct: 655 CLDKIDGYECACEPGYTGSMC 675
Score = 46.6 bits (109), Expect = 4e-04
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPK-SGTDIV 2395
C + C N GTC C C +SG CQ C +NPC N TC+ +G
Sbjct: 757 CESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCN 816
Query: 2396 CLCPYGRSGPLC 2407
CL PY +G C
Sbjct: 817 CLLPY--TGATC 826
Score = 46.6 bits (109), Expect = 4e-04
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
C+ C+N TC C+C Y G C + C ++PC NG TC+ T C
Sbjct: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNT-YKC 1207
Query: 2397 LCPYGRSGPLCTDAINITQP 2416
CP G G C ++ P
Sbjct: 1208 SCPRGTQGVHCEINVDDCNP 1227
Score = 46.6 bits (109), Expect = 4e-04
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 11/87 (12%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C ++PC N C++ +C C G G C ++ C + C G
Sbjct: 1268 VNECLSNPCDARGTQN---CVQRVNDFHCECRAGHTGRRCESVINGCKGK-----PCKNG 1319
Query: 2666 ATCI---SLPHGYTCFCPLGTTGIYCE 2689
TC + G+ C CP G G CE
Sbjct: 1320 GTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 46.2 bits (108), Expect = 5e-04
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCE--NNPCGNG 2383
G+N E ++ C + C+N G C+ C CP ++G+ C C+ N C NG
Sbjct: 251 GQNCEE-NIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNG 309
Query: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
TC G C+C G +G C++ I+
Sbjct: 310 GTCHNTHG-GYNCVCVNGWTGEDCSENID 337
Score = 46.2 bits (108), Expect = 5e-04
Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN--QSVSCL-NNLCLHQSLCIP-D 2930
D CG C NGG C + +C CL + G C S CL N C +Q C P
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTS 1407
Query: 2931 QSFSYSCLCTLGWVGRYC 2948
+S Y CLC + G C
Sbjct: 1408 ESPFYRCLCPAKFNGLLC 1425
Score = 45.8 bits (107), Expect = 7e-04
Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
Query: 2605 SVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
++ +C +PC NGGTC + C C G+ C V+ C+ + C
Sbjct: 678 NIDECAGNPCH-----NGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN-----SNPCVH 727
Query: 2665 GATCISLPHGYTCFCPLGTTGIYCE 2689
GA C +GY C C G +G C+
Sbjct: 728 GA-CRDSLNGYKCDCDPGWSGTNCD 751
Score = 45.1 bits (105), Expect = 0.001
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 2861 TEFGAKGGSNVGD-C-DGTACGYNTCRNGGECTV----NGTTFSCRCLPDWAGNTCNQSV 2914
TE GG+ VG C D C C+N G C V ++C C ++G C +
Sbjct: 43 TEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPL 102
Query: 2915 --SCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+CL N C + C Y C C GW G+ C+
Sbjct: 103 DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ 139
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 6/90 (6%)
Query: 2603 GRSVGQCHASP-CSLMKCGNGGTCIESGTS--VYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
GR+ CH + C C G C + + C C +G+ G C++ V C +P
Sbjct: 364 GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANP- 422
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C CI+ + C C G TG CE
Sbjct: 423 --CEHAGKCINTLGSFECQCLQGYTGPRCE 450
Score = 45.1 bits (105), Expect = 0.001
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
C + C+N+ TC+ C C Y G C+ + C ++PC + C+ K + C
Sbjct: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKI-NEFQC 514
Query: 2397 LCPYGRSGPLC 2407
CP G +G LC
Sbjct: 515 ECPTGFTGHLC 525
Score = 45.1 bits (105), Expect = 0.001
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
C++GG C G T CRC + G+ C V C + C + + C D YSC C G
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC-TDYLGGYSCKCVAG 1174
Query: 2943 WVGRYCENK 2951
+ G C +
Sbjct: 1175 YHGVNCSEE 1183
Score = 44.7 bits (104), Expect = 0.001
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Query: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLC-IPDQS--FSYSCLC 2939
TC NGG+C T +C C + G C CL+ C + C + D+ Y+C C
Sbjct: 30 TCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
Query: 2940 TLGWVGRYC 2948
LG+ G C
Sbjct: 90 ALGFSGPLC 98
Score = 44.3 bits (103), Expect = 0.002
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNP--CGNGATCVPKSGTDI 2394
CA + C N G C+ + C CP + G C+ C P C +G TC + G+
Sbjct: 144 CASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS-Y 202
Query: 2395 VCLCPYGRSGPLC 2407
C+C +GP C
Sbjct: 203 RCVCRATHTGPNC 215
Score = 43.9 bits (102), Expect = 0.003
Identities = 30/86 (34%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 2612 SPCSLMKCGNGGTCI---ESGTSVY-CNCTTGWKGSFC-TETVSTCDPEHDPPHHCSRGA 2666
+PC C N GTC G + Y C+C G+ G C T + C + C G
Sbjct: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNAC-----LTNPCRNGG 115
Query: 2667 TCISLP-HGYTCFCPLGTTGIYCEQA 2691
TC L Y C CP G +G C+QA
Sbjct: 116 TCDLLTLTEYKCRCPPGWSGKSCQQA 141
Score = 43.9 bits (102), Expect = 0.003
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
KC N GTC++ C C G+ G C V+ C P C+ + + C
Sbjct: 1237 KCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC---LSNPCDARGTQNCVQRVNDFHC 1293
Query: 2678 FCPLGTTGIYCEQALS 2693
C G TG CE ++
Sbjct: 1294 ECRAGHTGRRCESVIN 1309
Score = 42.0 bits (97), Expect = 0.010
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C + C NGGTC GI SF C CP FTG +C+ D
Sbjct: 987 CTESSCFNGGTC-----VDGINSFTCLCPPGFTGSYCQHD 1021
Score = 42.0 bits (97), Expect = 0.010
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 7/87 (8%)
Query: 2870 NVGDCDGTACGYNT---CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQS 2925
NV DC+ + C N G C +SC C P + G C V+ CL+N C +
Sbjct: 1221 NVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARG 1280
Query: 2926 L--CIPDQSFSYSCLCTLGWVGRYCEN 2950
C+ + + C C G GR CE+
Sbjct: 1281 TQNCV-QRVNDFHCECRAGHTGRRCES 1306
Score = 41.6 bits (96), Expect = 0.013
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C CR+GG C + C CL G C ++ C ++ C C+ D+ Y C
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCL-DKIDGYEC 664
Query: 2938 LCTLGWVGRYC 2948
C G+ G C
Sbjct: 665 ACEPGYTGSMC 675
Score = 41.2 bits (95), Expect = 0.016
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 2611 ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC-- 2668
A C ++C NGGTCI S C C + G C S+ +P C TC
Sbjct: 1349 ARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNP---CYNQGTCEP 1405
Query: 2669 ISLPHGYTCFCPLGTTGIYC 2688
S Y C CP G+ C
Sbjct: 1406 TSESPFYRCLCPAKFNGLLC 1425
Score = 40.8 bits (94), Expect = 0.021
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 2093 VSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
V P P+ C C N GTCH + G+ + C C L F+G C
Sbjct: 53 VGPRCQDPNPCLSTPCKNAGTCHVVD-RRGVADYACSCALGFSGPLC 98
Score = 40.8 bits (94), Expect = 0.021
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C+ + CHNGG+C + GI + CDC F G FCE+D
Sbjct: 911 CRPNPCHNGGSC-----TDGINTAFCDCLPGFRGTFCEED 945
Score = 38.9 bits (89), Expect = 0.081
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCI 2928
N+ DC + C TC + ++G + C C P + G+ CN ++ C N C + C
Sbjct: 641 NLDDCASSPCDSGTCLD----KIDG--YECACEPGYTGSMCNINIDECAGNPCHNGGTC- 693
Query: 2929 PDQSFSYSCLCTLGWVGRYC 2948
D ++C C G+ C
Sbjct: 694 EDGINGFTCRCPEGYHDPTC 713
Score = 38.1 bits (87), Expect = 0.14
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 6/86 (6%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLH 2923
G N+ DC AC + G C +F C C G C+ + +C++N C
Sbjct: 329 GEDCSENIDDCASAACFH-----GATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNE 383
Query: 2924 QSLCIPDQ-SFSYSCLCTLGWVGRYC 2948
S C + + C C G+ G C
Sbjct: 384 GSNCDTNPVNGKAICTCPSGYTGPAC 409
Score = 37.7 bits (86), Expect = 0.18
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 2091 TSVSPSVAAPSV-CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
T P+ P V C C NGGTC +G V+ +C C FTG+ CE++
Sbjct: 209 THTGPNCERPYVPCSPSPCQNGGTCRP----TGDVTHECACLPGFTGQNCEEN 257
Score = 37.0 bits (84), Expect = 0.31
Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDA 2143
C+ C NGGTC S+ F C CP F G CE DA
Sbjct: 1311 CKGKPCKNGGTCAVA--SNTARGFICKCPAGFEGATCENDA 1349
Score = 36.2 bits (82), Expect = 0.53
Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C + C NGG C G+ ++ C CP +TG++C +D
Sbjct: 261 CPGNNCKNGGAC-----VDGVNTYNCRCPPEWTGQYCTED 295
Score = 35.4 bits (80), Expect = 0.90
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 12/58 (20%)
Query: 2090 WTSVSPSVAAPSVCQQDV-------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
+T + P S CQ DV C +GGTC G S++C CP +TG C+
Sbjct: 1005 FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQ-----DGCGSYRCTCPQGYTGPNCQ 1057
Score = 35.0 bits (79), Expect = 1.2
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK-DAGLFFPSFNGNSYL 2156
+ C + C NGGTC + L+ ++C CP ++G+ C++ D P NG L
Sbjct: 104 NACLTNPCRNGGTCDLLTLT----EYKCRCPPGWSGKSCQQADPCASNPCANGGQCL 156
Score = 34.7 bits (78), Expect = 1.5
Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 5/46 (10%)
Query: 2097 VAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
V AP C C NGG C S SF C CP + G+ CE D
Sbjct: 829 VLAP--CAPSPCRNGGECRQ---SEDYESFSCVCPTGWQGQTCEVD 869
Score = 34.3 bits (77), Expect = 2.0
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 6/53 (11%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE-KDAGLFFPSFNGNS 2154
C C +G TCH + SF C+CP TG C DA + P G++
Sbjct: 339 CASAACFHGATCH-----DRVASFYCECPHGRTGLLCHLNDACISNPCNEGSN 386
Score = 34.3 bits (77), Expect = 2.0
Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 11/66 (16%)
Query: 2083 TQGVDTMWTSVSPSVAAP------SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTG 2136
T G++T + P + C D C NG C + + S+ C CP F+G
Sbjct: 923 TDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC-----TDCVDSYTCTCPAGFSG 977
Query: 2137 RFCEKD 2142
CE +
Sbjct: 978 IHCENN 983
Score = 34.3 bits (77), Expect = 2.0
Identities = 21/90 (23%), Positives = 32/90 (35%), Gaps = 6/90 (6%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
G + +V +C C +N C F C C G C ++ C C
Sbjct: 1261 GERCEGDVNECLSNPCDARGTQN---CVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
Query: 2923 HQSLCI--PDQSFSYSCLCTLGWVGRYCEN 2950
+ C + + + C C G+ G CEN
Sbjct: 1318 NGGTCAVASNTARGFICKCPAGFEGATCEN 1347
Score = 33.9 bits (76), Expect = 2.6
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 7/59 (11%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG--LFFPSFNGNSYLELP 2159
C C + G C I FQC+CP FTG C+ D P NG L+ P
Sbjct: 494 CASSPCLHNGRC-----LDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGP 547
Score = 33.5 bits (75), Expect = 3.4
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 15/56 (26%)
Query: 2095 PSVAAPSVCQQDV---------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
PS P+ C+QDV C +GGTCH + + S++C C TG CE+
Sbjct: 168 PSFHGPT-CRQDVNECGQKPGLCRHGGTCH-----NEVGSYRCVCRATHTGPNCER 217
Score = 32.7 bits (73), Expect = 5.8
Identities = 14/29 (48%), Positives = 15/29 (51%), Gaps = 5/29 (17%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCP 2131
C + CHNGGTC GI F C CP
Sbjct: 682 CAGNPCHNGGTC-----EDGINGFTCRCP 705
Score = 32.0 bits (71), Expect = 9.9
Identities = 12/38 (31%), Positives = 18/38 (47%), Gaps = 5/38 (13%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
C C NGG C ++C+CP +TG +C+
Sbjct: 1063 CDSSPCKNGGKCWQTH-----TQYRCECPSGWTGLYCD 1095
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 613 bits (1582), Expect = e-175
Identities = 361/1145 (31%), Positives = 511/1145 (44%), Gaps = 140/1145 (12%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDA-CSFKPCKNNGSCINKRENWDEQAYE 241
C G CL+ S Y C C F+G+YC L C+ PC N G+C R+ D +E
Sbjct: 192 CQHGGTCLNLPGS--YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTC---RQTGDF-TFE 245
Query: 242 CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
C C P F G C I C H C +G N++ C C Q++G FC C+
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ 305
Query: 302 --LFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICS 359
G C N + Y C G S + ++ + + C G+ CI C+C
Sbjct: 306 PNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCP 365
Query: 360 PIFTDLLCKSIQTSCESFPLRNNATC--KKCEKDYPCSCISGFTEKNCEKAIDHCKLLSI 417
LLC + +C S P A C Y C+C G+ +C + +D C + +
Sbjct: 366 EGKAGLLCH-LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANS 424
Query: 418 N-CLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQ 476
N C + C N G F C+ G C ++ H C T C DK
Sbjct: 425 NPCEHAGKCVNTDGAFHCECLKGYAGPRCEM--DINECHSDPCQNDAT----CLDK-IGG 477
Query: 477 FEYVWQLGFAGSEGE----KCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK 532
F + GF G E +CQ + C + V+ + N C P T
Sbjct: 478 FTCLCMPGFKGVHCELEINECQ---------SNPCVNNGQCVD--KVNRFQCLCPPGFTG 526
Query: 533 EICA------------NGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAV 580
+C NG C+ + E + C + G + EN + + C H
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ--CATGFTGVLCEENIDNCDPDPCHH-GQ 583
Query: 581 CKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLAL--SHNCNC----SGLQR 634
C+D I+ C C+ Y+G +C +D C + ++ G C+ L + CNC SG+
Sbjct: 584 CQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLN-DGRCIDLVNGYQCNCQPGTSGVN- 641
Query: 635 YERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGA 694
CEI+ +DC S C +G + Y C PGF G +C IDIDECAS+PC+ GA
Sbjct: 642 -----CEINFDDCASNPCIHGICMDGINRYSC-VCSPGFTGQRCNIDIDECASNPCRKGA 695
Query: 695 TCIDQPGNYFCQCVPP------FKVVD-----------------GFSCLCNPGYVGIRCE 731
TCI+ + C C + V+ G+ CLC+ G+VGI CE
Sbjct: 696 TCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCE 755
Query: 732 QDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYK 791
D ++C+ N C++ TC +L Y+C C ++G C+ +EC NPC N TC D
Sbjct: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
Query: 792 SYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYN 851
Y C C +TG+NC + C +PC N +C ES + CLC P + GQ C +
Sbjct: 816 GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875
Query: 852 LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNN 911
C + PC N+ C + C C F G +CE D+ DCL CQ+ G C D VN
Sbjct: 876 EC--ISKPCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT 932
Query: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK 971
F C+C PGF+G C+ ++NEC SEPCKN GTC D N + C C+ + G CE ++N+C
Sbjct: 933 FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECT 992
Query: 972 ISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCK 1031
S C + CV + ++CLC G+TG C ++EC S PCL++G C+DG+ Y C C
Sbjct: 993 ESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP 1052
Query: 1032 SGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIP--- 1087
G+ G +C+T N C +PC + G C + E C C + C + C
Sbjct: 1053 LGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRR 1112
Query: 1088 -------CMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAE----------------- 1123
C + G C + + C CP GYTG+YCE+ +D CA
Sbjct: 1113 GVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYR 1172
Query: 1124 ----------------PELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSS 1167
E + C NGG C+D H F C C PG G CE NI++C+
Sbjct: 1173 CECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNH-FKCSCPPGTRGLLCEENIDDCAR 1231
Query: 1168 SP-CLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVHE---LCMENEPGSTCL 1222
P CL+G C D I GY C+C PG++G CE ++ EC+ N C E C++ C+
Sbjct: 1232 GPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCV 1291
Query: 1223 CTPGF 1227
C F
Sbjct: 1292 CRSAF 1296
Score = 609 bits (1570), Expect = e-173
Identities = 348/1100 (31%), Positives = 517/1100 (47%), Gaps = 94/1100 (8%)
Query: 185 GHGKCLSEAWSKTYS-----CHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQA 239
G+ C++E TY C C F G+YCQ D C C+N G+C+ +
Sbjct: 31 GYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKA-- 88
Query: 240 YECVCHPPFTGKNCSEIIGQCQPHVCF-------HGNCSNITSNSFICECDEQFSGPFCE 292
C C FTG++C H CF G C ++ +++ C C F+G C+
Sbjct: 89 -TCRCASGFTGEDCQ----YSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
Query: 293 VSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLV-PCQNGTDCIKIS 351
+ C+S C ++ ++ +C G + Q ETDV+E + CQ+G C+ +
Sbjct: 144 WT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLP 202
Query: 352 NDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKC-EKDYPCSCISGFTEKNCEKAID 410
C C FT C S+ C P N TC++ + + C+C+ GF CE+ ID
Sbjct: 203 GSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID 262
Query: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQ 470
C + C N C + + + C P T C + L+ + C G G C
Sbjct: 263 DCP--NHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNG----GTCA 316
Query: 471 DKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEG 530
++ + V G++G + C ID F A+CT +T ++ + SC P EG
Sbjct: 317 NRN-GGYGCVCVNGWSGDD---CSENIDDCAF--ASCTPGSTCID--RVASFSCMCP-EG 367
Query: 531 TKEI------------CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTD---DQENEC 575
+ C G C + + +Y C + G E+ + N C
Sbjct: 368 KAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPC 427
Query: 576 QHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRY 635
+H C + C C Y G C ++++ C + CL C + +
Sbjct: 428 EHAGKCVNTDGAFHCECLKGYAGPRCEMDINEC-HSDPCQNDATCLDKIGGFTCLCMPGF 486
Query: 636 ERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGAT 695
+ CE++ +C+S C N F C PGF G C+IDID+C+S PC NGA
Sbjct: 487 KGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAK 546
Query: 696 CIDQPGNYFCQCVPPFKVV-----------------------DGFSCLCNPGYVGIRCEQ 732
CID P Y CQC F V D ++C+CNPGY+G C
Sbjct: 547 CIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSD 606
Query: 733 DIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKS 792
ID+C + C ++ C DL YQC C G CE ++C NPC + C D
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPC-IHGICMDGINR 665
Query: 793 YRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNL 852
Y C C+ G+TGQ C+ +I+EC S+PC G C F C+CP C+ + N
Sbjct: 666 YSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNE 723
Query: 853 CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNF 912
C L NPC + + L + C+C + G NCE+D +CL CQ+ G C+++VN +
Sbjct: 724 C--LSNPCIHGNCTGGL--SGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY 779
Query: 913 RCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKI 972
RC C+ GF G C++ I+EC+S PC N GTC D + + C+C Y G C+ + C
Sbjct: 780 RCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSP 839
Query: 973 SPCLDEENCVY--RTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDC 1030
+PC + C + Y CLCAPG+ G C I++DEC+S+PC++ G+C + Y C+C
Sbjct: 840 NPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCEC 899
Query: 1031 KSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCM 1089
GF G CE + +DCL+NPC + G C + +N + C C T +C+ +N+C S PC
Sbjct: 900 PPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCK 959
Query: 1090 NEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRC 1149
N G C + +TC C G+ G +CE +I+ C E C NGG CVDG ++F C C
Sbjct: 960 NGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESS-----CFNGGTCVDGI-NSFSCLC 1013
Query: 1150 LPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE-CIPNSCV 1208
GF+G FC INECSS PCL+ C D + Y C C G++G +C+ + C + C
Sbjct: 1014 PVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCK 1073
Query: 1209 HE-LCMENEPGSTCLCTPGF 1227
++ C++ + S CLC G+
Sbjct: 1074 NKGTCVQKKAESQCLCPSGW 1093
Score = 583 bits (1503), Expect = e-166
Identities = 348/1083 (32%), Positives = 497/1083 (45%), Gaps = 145/1083 (13%)
Query: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
W A C P C + C G C + + C+C E F G +C+
Sbjct: 10 WALLALWLCCAAPAHALQCRDGYEPCVNE----GMCVTYHNGTGYCKCPEGFLGEYCQ-H 64
Query: 295 AKPCVSLLFWKRGICPNSS--SAYTYECPKGSSSQNGETDVSEFSLV--PCQNGTDCIKI 350
PC G C + T C G + ++ + S V PC NG C +
Sbjct: 65 RDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHML 124
Query: 351 SNDVM-CICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI 409
S D C C FT C+ +C S P N +TC + C C++GFT + CE +
Sbjct: 125 SRDTYECTCQVGFTGKECQWTD-ACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDV 183
Query: 410 DHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYL-IHQHLCYCGVTFHGI 468
+ C + +C + C N+ G ++ C G T C ++Y+ C G G
Sbjct: 184 NECDIPG-HCQHGGTCLNLPGSYQCQCPQGFTGQYC---DSLYVPCAPSPCVNG----GT 235
Query: 469 CQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSC---W 525
C+ G FE GF EG C+ ID C V+ N C W
Sbjct: 236 CRQTGDFTFECNCLPGF---EGSTCERNIDDC--PNHRCQNGGVCVDGVNTYNCRCPPQW 290
Query: 526 FPHEGTKEI---------CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQ 576
T+++ C NG +C + Y +C W+G+ EN D C
Sbjct: 291 TGQFCTEDVDECLLQPNACQNGGTCANRNGG--YGCVCVNGWSGDDCSENIDDCAFASCT 348
Query: 577 HEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCN----CSGL 632
+ C D + C C G LC ++ D C+ N H L ++ N C+
Sbjct: 349 PGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISN---PCHKGALCDTNPLNGQYICTCP 404
Query: 633 QRYERNICEIDTEDCKSAS---CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHP 689
Q Y+ C D ++C A+ C++ + G F +C+ G+ G +CE+DI+EC S P
Sbjct: 405 QGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDP 464
Query: 690 CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCK 749
C+N ATC+D+ G GF+CLC PG+ G+ CE +I++C N C +N C
Sbjct: 465 CQNDATCLDKIG--------------GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCV 510
Query: 750 DLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEE 809
D +QC+C + G C+ + ++C PC N + C D Y C+C +G+TG C E
Sbjct: 511 DKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEEN 570
Query: 810 INECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLAL 869
I+ CD DPC +G C + + C+C P Y G C + + C +PC N+ C+ L
Sbjct: 571 IDNCDPDPCHHGQ-CQDGI--DSYTCICNPGYMGAICSDQIDEC--YSSPCLNDGRCIDL 625
Query: 870 VDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEI 929
V+ Q C C+ G NCEI+ DC C +G C D +N + C+C PGF+G C I+I
Sbjct: 626 VNGYQ-CNCQPGTSGVNCEINFDDCASNPCI-HGICMDGINRYSCVCSPGFTGQRCNIDI 683
Query: 930 NECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYN 989
+EC+S PC+ TC++ N F C C H P C VN+C +PC+ NC GY
Sbjct: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGYK 742
Query: 990 CLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSN 1049
CLC G+ GINCE++ +ECLS PC + G C + +N Y C CK GF G +C+ N ++C SN
Sbjct: 743 CLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASN 802
Query: 1050 PCLH-GRCTELINEYPCSCDADGTSTQCK------------------------------- 1077
PCL+ G C + I+ Y C C T C+
Sbjct: 803 PCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCA 862
Query: 1078 ---------IKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNC-AEPELN 1127
I I++C S PCMN G C + + C CP G++G CE+ ID+C A P
Sbjct: 863 PGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP--- 919
Query: 1128 SVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKC 1187
C NGG C+DG +TF C CLPGF+G C+ ++NEC S PC +G C D++N Y CKC
Sbjct: 920 ---CQNGGSCMDGV-NTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKC 975
Query: 1188 QPGWSGHHCENEL-ECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCL 1246
Q G+ G HCEN + EC +SC + G TC+ D I +CL
Sbjct: 976 QAGFDGVHCENNINECTESSCFN--------GGTCV---------------DGINSFSCL 1012
Query: 1247 TPI 1249
P+
Sbjct: 1013 CPV 1015
Score = 569 bits (1467), Expect = e-161
Identities = 351/1139 (30%), Positives = 497/1139 (43%), Gaps = 146/1139 (12%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
C+ C+ S +SC C +G C DAC PC C N Y C
Sbjct: 347 CTPGSTCIDRVAS--FSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQ---YIC 401
Query: 243 VCHPPFTGKNCSEIIGQC---QPHVCFH-GNCSNITSNSFICECDEQFSGPFCEVSAKPC 298
C + G +C+E + +C + C H G C N T +F CEC + ++GP CE+ C
Sbjct: 402 TCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN-TDGAFHCECLKGYAGPRCEMDINEC 460
Query: 299 VSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCIC 358
S C + +T C G + E +++E PC N C+ N C+C
Sbjct: 461 HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLC 520
Query: 359 SPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHC------ 412
P FT +C+ C S P N A C Y C C +GFT CE+ ID+C
Sbjct: 521 PPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCH 580
Query: 413 -----------------------------KLLSINCLNEEWCFNIIGRFKYVCIPGCTKN 443
+ S CLN+ C +++ ++ C PG +
Sbjct: 581 HGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGV 640
Query: 444 PCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFL 503
C I+ C HGIC D G ++ V GF G ++C ID
Sbjct: 641 NCE-------INFDDCASNPCIHGICMD-GINRYSCVCSPGFTG---QRCNIDIDE---C 686
Query: 504 AAN-CTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS-CLSEE--------DSQEYRYL 553
A+N C + AT +N N C P C + + CLS Y+ L
Sbjct: 687 ASNPCRKGATCINGV--NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCL 744
Query: 554 CFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHS 613
C W G + + N CQ+ C + +N RC+C + G C VN+D C N
Sbjct: 745 CDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPC 804
Query: 614 ISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGY--FFRKCVP 671
++ G C C + Y C+ C C+N + + C P
Sbjct: 805 LN-QGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAP 863
Query: 672 GFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVD---------------- 715
G++G +C IDIDEC S PC N C + G+Y C+C P F +D
Sbjct: 864 GWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNG 923
Query: 716 --------GFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF 767
FSCLC PG+ G +C+ D+++C+ C++ TC D SY C C + ++G
Sbjct: 924 GSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVH 983
Query: 768 CEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHES 827
CE NEC + C N TC D S+ C C G+TG C EINEC S PC+N G C +
Sbjct: 984 CENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDG 1043
Query: 828 TIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
G + C CP YTG+ C NLC +PC+N TC+ A C+C + G C
Sbjct: 1044 L--GTYRCSCPLGYTGKNCQTLVNLCS--RSPCKNKGTCVQK-KAESQCLCPSGWAGAYC 1098
Query: 888 EIDVKDCLFLS----------CQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
++ C + CQ G C + N C C G++GS CE +++EC+S PC
Sbjct: 1099 DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPC 1158
Query: 938 KNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYT 997
++ TC D + C C P Y G CE +V++C+ PC + C+ + + C C PG
Sbjct: 1159 QHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR 1218
Query: 998 GINCEINLDECLSEP-CLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-- 1054
G+ CE N+D+C P CL+ G C+D I Y+C C GF G CE + N+CLSNPC
Sbjct: 1219 GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGS 1278
Query: 1055 -RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAH---GFTCICPRGYT 1110
C +L N+Y C C + T C+ ++ C +PC+N G C +++ GF C CP G++
Sbjct: 1279 LDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 1111 GAYCEKSIDNCAEPELNSVICLNGGICV---DGPGHTFDCRCLPGFSGQFCEININECSS 1167
GA C+ S C + V C G CV GP C C S + CE + C+S
Sbjct: 1339 GARCQSS---CGQ-----VKCRKGEQCVHTASGP----RCFCP---SPRDCE---SGCAS 1380
Query: 1168 SPCLHGADCEDHING--YVCKCQPGWSGHHCE---NELECIPNSCVHELCMENEPGSTC 1221
SPC HG C Y C+C P +SG CE P +C+ + C + C
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVC 1439
Score = 373 bits (957), Expect = e-102
Identities = 267/986 (27%), Positives = 393/986 (39%), Gaps = 127/986 (12%)
Query: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVC 244
HG C+ YSC C P F+G+ C ++D C+ PC+ +CIN + C+C
Sbjct: 656 HGICMDGI--NRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCIN-----GVNGFRCIC 708
Query: 245 HPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFW 304
+C + +C + C HGNC+ S + C CD + G CEV C+S
Sbjct: 709 PEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG-YKCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 305 KRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTD 364
G C N + Y C KG N + ++ E + PC N C + C C +T
Sbjct: 768 NGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTG 827
Query: 365 LLCKSIQTSCESFPLRNNATCKKCE--KDYPCSCISGFTEKNCEKAIDHCKLLSINCLNE 422
C+++ C P N A CK+ + Y C C G+ + C ID C +S C+N
Sbjct: 828 KNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC--ISKPCMNH 885
Query: 423 EWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQ 482
C N G + C PG + C +++ + C G G C D G F +
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCE--EDIDDCLANPCQNG----GSCMD-GVNTFSCLCL 938
Query: 483 LGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEG----------TK 532
GF G +KCQ D L+ C T + C +G T+
Sbjct: 939 PGFTG---DKCQ--TDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTE 993
Query: 533 EICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSC 592
C NG +C+ +S + LC + + G+ L + + C +E C D + RCSC
Sbjct: 994 SSCFNGGTCVDGINS--FSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSC 1051
Query: 593 SLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASC 652
L Y G+ C V+ C G C+ C + C++ C A+
Sbjct: 1052 PLGYTGKNCQTLVNLC-SRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAAS 1110
Query: 653 KNGTTSTHLRGY----------FFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGN 702
+ G HL + + +C G+ G+ CE +DECAS+PC++GATC D G
Sbjct: 1111 RRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGG 1170
Query: 703 YFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSD 762
Y C+CVP GY G+ CE ++D+C C++ TC DL ++C C
Sbjct: 1171 YRCECVP--------------GYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPG 1216
Query: 763 WEGNFCEQESNECKMNP-CKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNG 821
G CE+ ++C P C N C D Y C C G+ G+ C +INEC S+PC +
Sbjct: 1217 TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSE 1276
Query: 822 GLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICR-- 879
G + ++C+C +TG+ C ++C + PC N TC + ICR
Sbjct: 1277 GSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQM--PCLNGGTCAVASNMPDGFICRCP 1334
Query: 880 EEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKN 939
F G C+ C + C+ C + RC C S CE + C+S PC++
Sbjct: 1335 PGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCE---SGCASSPCQH 1385
Query: 940 NGTCVDLTN--RFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYT 997
G+C + C C P + G CEL P
Sbjct: 1386 GGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPA---------------------- 1423
Query: 998 GINCEINLDECLSEPC---LHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSN-PC-- 1051
CLS+ C DGVC + N + C G E +C S PC
Sbjct: 1424 ---------TCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWD 1474
Query: 1052 -LHGRCTELINEYPCSCD---ADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPR 1107
++ +C EL N C D G S CK D + C + + C
Sbjct: 1475 YINNQCDELCNTVECLFDNFECQGNSKTCKY---DKYCADHFKDNHCDQGCNSEEC---- 1527
Query: 1108 GYTGAYC-EKSIDNCAEPELNSVICL 1132
G+ G C +N AE L V+ +
Sbjct: 1528 GWDGLDCAADQPENLAEGTLVIVVLM 1553
Score = 94.4 bits (233), Expect = 2e-18
Identities = 95/350 (27%), Positives = 145/350 (41%), Gaps = 52/350 (14%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C+ C NGGTC++ S C C G+ GSFC ++ C H C TC+
Sbjct: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS-----SHPCLNEGTCVDGLG 1045
Query: 2674 GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGIL 2733
Y C CPLG TG C+ +++ S N+ V+KK + Q L G
Sbjct: 1046 TYRCSCPLGYTGKNCQTLVNLCSRSPCKNK-------GTCVQKKA----ESQCLCPSG-- 1092
Query: 2734 FYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETL---QKVTINGSTWHIIKA-- 2788
+G + + V+ + R +++E L V IN H +
Sbjct: 1093 ---------WAGAYCDVPNVSCDIA----ASRRGVLVEHLCQHSGVCINAGNTHYCQCPL 1139
Query: 2789 GRVGA--EGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPM-AIENEPVGFQ 2845
G G+ E LD N + +T + + G +N + +N+P
Sbjct: 1140 GYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNG 1199
Query: 2846 G-CIRQVIINNQELQLTEFGAKG---GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRC 2901
G CI ++N+ + G +G N+ DC A G + C NGG+C +SCRC
Sbjct: 1200 GTCID--LVNHFKCSCPP-GTRGLLCEENIDDC---ARGPH-CLNGGQCMDRIGGYSCRC 1252
Query: 2902 LPDWAGNTCNQSVS-CLNNLCLHQ-SLCIPDQSFSYSCLCTLGWVGRYCE 2949
LP +AG C ++ CL+N C + SL + Y C+C + GR+CE
Sbjct: 1253 LPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Score = 84.0 bits (206), Expect = 2e-15
Identities = 91/374 (24%), Positives = 140/374 (37%), Gaps = 48/374 (12%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
C C N+G C + + CECP +SG C+ C NPC NG +C+ T C
Sbjct: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSC 935
Query: 2397 LCPYGRSGPLCTDAIN--ITQPRFSGTDAFGY-TSFLAYSRISDISFHYEFHLKFQLANN 2453
LC G +G C +N +++P +G Y S+ + H E NN
Sbjct: 936 LCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE--------NN 987
Query: 2454 HSALQNNLIFFTGQKGHGLNGDDFLA-VGLLNGSVVYSYNLGSGIASIRSEPLNLSLGVH 2512
+ + F G G+N L VG ++ N S + LG +
Sbjct: 988 INECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTY 1047
Query: 2513 TV-----HLGKFFQE--GWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPN 2565
+ GK Q KNK + + + G Y + +PN
Sbjct: 1048 RCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCD-----VPN 1102
Query: 2566 -GADFKNGFQGCIFTLQVRTEKDGHFRGLGN------PEGHPNA--GRSVGQCHASPCSL 2616
D +G + ++ + G GN P G+ + + +C ++PC
Sbjct: 1103 VSCDIAASRRGVL--VEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQ- 1159
Query: 2617 MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
+G TC + C C G++G C V C ++ P C G TCI L + +
Sbjct: 1160 ----HGATCSDFIGGYRCECVPGYQGVNCEYEVDEC--QNQP---CQNGGTCIDLVNHFK 1210
Query: 2677 CFCPLGTTGIYCEQ 2690
C CP GT G+ CE+
Sbjct: 1211 CSCPPGTRGLLCEE 1224
Score = 78.2 bits (191), Expect = 1e-13
Identities = 88/380 (23%), Positives = 130/380 (34%), Gaps = 82/380 (21%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHD 2657
P G++ Q +PCS C N C ES S C C GW+G CT + C +
Sbjct: 824 PYTGKNC-QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP- 881
Query: 2658 PPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKK 2717
C C + Y C CP G +G+ CE+ + + N S M
Sbjct: 882 ----CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCM---------- 927
Query: 2718 THIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVT 2777
DG+ ++ L +GD +T + E L +
Sbjct: 928 ------------DGVNTFSCLCLPGFTGDKC-----------------QTDMNECLSEPC 958
Query: 2778 INGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAI 2837
NG T + DG++ + S N + G++S + + P
Sbjct: 959 KNGGTCSDY-VNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCP--- 1014
Query: 2838 ENEPVGFQG--CIRQVIINNQELQLTEFGAKGGSNVGDCDG-------------TACGYN 2882
VGF G C+ ++ + L E G C C +
Sbjct: 1015 ----VGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRS 1070
Query: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC----------LNNLCLHQSLCIPDQ 2931
C+N G C C C WAG C+ +VSC + +LC H +CI
Sbjct: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130
Query: 2932 SFSYSCLCTLGWVGRYCENK 2951
+ Y C C LG+ G YCE +
Sbjct: 1131 NTHY-CQCPLGYTGSYCEEQ 1149
Score = 73.6 bits (179), Expect = 3e-12
Identities = 34/85 (40%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C C NG TC C C TG+ G C V+ CD P HC G TC++LP
Sbjct: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI----PGHCQHGGTCLNLPG 203
Query: 2674 GYTCFCPLGTTGIYCEQALSISDPS 2698
Y C CP G TG YC+ PS
Sbjct: 204 SYQCQCPQGFTGQYCDSLYVPCAPS 228
Score = 66.6 bits (161), Expect = 4e-10
Identities = 29/79 (36%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 2613 PCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
PC+ C NGGTC ++G + CNC G++GS C + C P H C G C+
Sbjct: 224 PCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC-----PNHRCQNGGVCVDG 278
Query: 2672 PHGYTCFCPLGTTGIYCEQ 2690
+ Y C CP TG +C +
Sbjct: 279 VNTYNCRCPPQWTGQFCTE 297
Score = 66.2 bits (160), Expect = 5e-10
Identities = 90/341 (26%), Positives = 128/341 (37%), Gaps = 69/341 (20%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG--LFFPSFNGNSYLE--- 2157
C C N G CH + G S+ C+CP F+G CE+D L P NG S ++
Sbjct: 877 CISKPCMNHGLCHN---TQG--SYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN 931
Query: 2158 ------LP-FLKFVLEKEHNRTVTIYLTIKTNSLNGTIL-YSNGNNCGKQFLHLFLVEGR 2209
LP F + + N ++ + GT Y N C Q G
Sbjct: 932 TFSCLCLPGFTGDKCQTDMNECLS-----EPCKNGGTCSDYVNSYTCKCQ-------AGF 979
Query: 2210 PSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKK 2269
V C N+ N T S+ ++ T + PVG G C+ E+ P +
Sbjct: 980 DGVH--CENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 2270 DTEISHASQAYFESMFLGHIPANVQ-----------------IHKKAGPVY----GFRGC 2308
T + Y S LG+ N Q + KKA G+ G
Sbjct: 1038 GTCVDGLG-TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGA 1096
Query: 2309 ILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGK 2368
D+ + + I +R G +E HLC+++G CI+ +C+CP Y+G
Sbjct: 1097 YCDVPNVSCD---IAASRRGVLVE---------HLCQHSGVCINAGNTHYCQCPLGYTGS 1144
Query: 2369 LC--QFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
C Q C +NPC +GATC G C C G G C
Sbjct: 1145 YCEEQLDECASNPCQHGATCSDFIG-GYRCECVPGYQGVNC 1184
Score = 65.9 bits (159), Expect = 6e-10
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C +C NGG C++ + C C W G FCTE V C + P+ C G TC +
Sbjct: 264 CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQ---PNACQNGGTCANRNG 320
Query: 2674 GYTCFCPLGTTGIYCEQALSISDPSFRS 2701
GY C C G +G C + +I D +F S
Sbjct: 321 GYGCVCVNGWSGDDCSE--NIDDCAFAS 346
Score = 63.5 bits (153), Expect = 3e-09
Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
Query: 2873 DC--DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIP 2929
DC D C N C+NGG C TFSC CLP + G+ C ++ CL+ C + C
Sbjct: 907 DCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTC-S 965
Query: 2930 DQSFSYSCLCTLGWVGRYCENKTSFST 2956
D SY+C C G+ G +CEN + T
Sbjct: 966 DYVNSYTCKCQAGFDGVHCENNINECT 992
Score = 63.2 bits (152), Expect = 4e-09
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
+ +C ++PC N G C++ C C G+ G C + C C G
Sbjct: 495 INECQSNPCV-----NNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP-----CLNG 544
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
A CI P+GY C C G TG+ CE+ + DP
Sbjct: 545 AKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
Score = 63.2 bits (152), Expect = 4e-09
Identities = 36/118 (30%), Positives = 42/118 (35%), Gaps = 36/118 (30%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH---- 2661
V Q CS C NG CI+ C C TG+ G C E + CDP DP HH
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP--DPCHHGQCQ 585
Query: 2662 ------------------------------CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C CI L +GY C C GT+G+ CE
Sbjct: 586 DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCE 643
Score = 61.6 bits (148), Expect = 1e-08
Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 5/79 (6%)
Query: 2874 CDG--TACGYNTCRNGGECTVNGT-TFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIP 2929
CD C + C NGG C G TF C CLP + G+TC +++ C N+ C + +C+
Sbjct: 218 CDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCV- 276
Query: 2930 DQSFSYSCLCTLGWVGRYC 2948
D +Y+C C W G++C
Sbjct: 277 DGVNTYNCRCPPQWTGQFC 295
Score = 60.5 bits (145), Expect = 3e-08
Identities = 88/393 (22%), Positives = 126/393 (32%), Gaps = 101/393 (25%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCV--------- 2387
C C+N+ TC+ C C + G C+ C++NPC N CV
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 2388 -PKSGTDIVCLCPYG--RSGPLCTDAINITQPR-FSGTDAFGYTSFLAYSRISDISFHYE 2443
P T VC S P A I P + A G+T L I +
Sbjct: 520 CPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPD-- 577
Query: 2444 FHLKFQLANNHSALQNNLIFFTGQKGHGLNG----------------DDFLAVGLLNGSV 2487
+H Q+ + +T G G +D + L+NG
Sbjct: 578 -------PCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNG-- 628
Query: 2488 VYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVF 2547
Y N G + + E + DD + I + G+N +
Sbjct: 629 -YQCNCQPGTSGVNCE---------------------INFDDCASNPCIHGICMDGINRY 666
Query: 2548 SQFYVGGYS---------EYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEG 2598
S G++ E + GA NG G FR + PEG
Sbjct: 667 SCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNG--------------FRCIC-PEG 711
Query: 2599 --HPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH 2656
HP+ V +C ++PC G C + C C GW G C + C
Sbjct: 712 PHHPSCYSQVNECLSNPCI------HGNCTGGLSGYKCLCDAGWVGINCEVDKNEC---- 761
Query: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
+ C G TC +L +GY C C G G C+
Sbjct: 762 -LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ 793
Score = 59.7 bits (143), Expect = 4e-08
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C P + C NGGTC C C GW G C+E + C C+ G
Sbjct: 299 VDECLLQPNA---CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFAS-----CTPG 350
Query: 2666 ATCISLPHGYTCFCPLGTTGIYC 2688
+TCI ++C CP G G+ C
Sbjct: 351 STCIDRVASFSCMCPEGKAGLLC 373
Score = 59.7 bits (143), Expect = 4e-08
Identities = 33/81 (40%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 2333 NCHV--PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVP 2388
NC V CA + C N GTC D C C Y+GK CQ A C NPC N A C
Sbjct: 791 NCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKE 850
Query: 2389 KSGTD-IVCLCPYGRSGPLCT 2408
+ CLC G G CT
Sbjct: 851 SPNFESYTCLCAPGWQGQRCT 871
Score = 59.3 bits (142), Expect = 6e-08
Identities = 85/349 (24%), Positives = 122/349 (34%), Gaps = 75/349 (21%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG--LFFPSFNGNSYLELPF 2160
C + C NGG+C G+ +F C C FTG C+ D L P NG + +
Sbjct: 915 CLANPCQNGGSC-----MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDY-- 967
Query: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQ--FLHLFLVEGRPSVKYGCGN 2218
V Y +G +N N C + F V+G S + C
Sbjct: 968 ------------VNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINS--FSCLC 1013
Query: 2219 SQNILTVSANYSINTNAFTPI-----------TIRYTTPVGSPGVVCMIEMTADGKPPVQ 2267
+ IN + P T R + P+G G C + + P +
Sbjct: 1014 PVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCK 1073
Query: 2268 KKDTEISHA--SQAYFESMFLG---HIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFII 2322
K T + SQ S + G +P NV A RG +++ + I
Sbjct: 1074 NKGTCVQKKAESQCLCPSGWAGAYCDVP-NVSCDIAASR----RGVLVEHLCQHSGVCI- 1127
Query: 2323 DEARHGKNIENCHVPW-------------CAHHLCRNNGTCISDNENLFCECPRLYSGKL 2369
+ N C P CA + C++ TC CEC Y G
Sbjct: 1128 ----NAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVN 1183
Query: 2370 CQFA--SCENNPCGNGATCVPKSGTDIV----CLCPYGRSGPLCTDAIN 2412
C++ C+N PC NG TC+ D+V C CP G G LC + I+
Sbjct: 1184 CEYEVDECQNQPCQNGGTCI-----DLVNHFKCSCPPGTRGLLCEENID 1227
Score = 58.9 bits (141), Expect = 8e-08
Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCL--NNLCLHQSL 2926
N+ DC + C+NGG C T++CRC P W G C + V CL N C +
Sbjct: 260 NIDDCPN-----HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGT 314
Query: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
C +++ Y C+C GW G C
Sbjct: 315 C-ANRNGGYGCVCVNGWSGDDC 335
Score = 58.5 bits (140), Expect = 1e-07
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGAT 2385
G + EN ++ C C N GTC+ + C CP ++G C + C ++PC N T
Sbjct: 981 GVHCEN-NINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGT 1039
Query: 2386 CVPKSGTDIVCLCPYGRSGPLCTDAINI 2413
CV GT C CP G +G C +N+
Sbjct: 1040 CVDGLGT-YRCSCPLGYTGKNCQTLVNL 1066
Score = 57.8 bits (138), Expect = 2e-07
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 9/89 (10%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
N V +C PC NGGTCI+ C+C G +G C E + C P
Sbjct: 1183 NCEYEVDECQNQPCQ-----NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDC--ARGP-- 1233
Query: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
HC G C+ GY+C C G G CE
Sbjct: 1234 HCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
Score = 56.2 bits (134), Expect = 5e-07
Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Query: 2873 DCDGT-ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-C-LNNLCLHQSLCIP 2929
+C T AC + C NG CT FSC+CL + G C V+ C + C H C+
Sbjct: 141 ECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL- 199
Query: 2930 DQSFSYSCLCTLGWVGRYCEN 2950
+ SY C C G+ G+YC++
Sbjct: 200 NLPGSYQCQCPQGFTGQYCDS 220
Score = 56.2 bits (134), Expect = 5e-07
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
P+G+ A + + + C + G C+ + + +C C G+ G C ++ C
Sbjct: 404 PQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINEC--- 460
Query: 2656 HDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
H P C ATC+ G+TC C G G++CE
Sbjct: 461 HSDP--CQNDATCLDKIGGFTCLCMPGFKGVHCE 492
Score = 56.2 bits (134), Expect = 5e-07
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 6/103 (5%)
Query: 2873 DCDGTACGYNTCRNGGEC--TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIP 2929
+ D C N C+NGG C VNG + C C + G C ++ C +N CL+Q C
Sbjct: 755 EVDKNECLSNPCQNGGTCDNLVNG--YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFD 812
Query: 2930 DQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNY 2972
D S Y+C C L + G+ C+ + + N+ + PN+
Sbjct: 813 DIS-GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNF 854
Score = 55.5 bits (132), Expect = 8e-07
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 2853 INNQELQLTEFGAKGGSNVGDCDGTA-CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN 2911
+N Q + G KG D D A N C + G+C F C CL +AG C
Sbjct: 395 LNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE 454
Query: 2912 QSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
++ C ++ C + + C+ D+ ++CLC G+ G +CE
Sbjct: 455 MDINECHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCE 492
Score = 53.9 bits (128), Expect = 2e-06
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
D D N C+NGG C + C C+ W+G+ C++++ C C S CI D+
Sbjct: 298 DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI-DR 356
Query: 2932 SFSYSCLCTLGWVGRYC 2948
S+SC+C G G C
Sbjct: 357 VASFSCMCPEGKAGLLC 373
Score = 53.5 bits (127), Expect = 3e-06
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASC--ENNPCGNGATCVPKSGTDI 2394
C +H C+N G C+ C CP ++G+ C C + N C NG TC ++G
Sbjct: 264 CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNG-GY 322
Query: 2395 VCLCPYGRSGPLCTDAIN 2412
C+C G SG C++ I+
Sbjct: 323 GCVCVNGWSGDDCSENID 340
Score = 53.5 bits (127), Expect = 3e-06
Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+C ++PC NGGTC C C G+KG C + C + C T
Sbjct: 760 ECLSNPCQ-----NGGTCDNLVNGYRCTCKKGFKGYNCQVNIDEC-----ASNPCLNQGT 809
Query: 2668 CISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
C GYTC C L TG C+ L+ P+
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPN 840
Score = 53.1 bits (126), Expect = 4e-06
Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSF-SYS 2936
C N C N G C + + ++C C+ + G C ++ C N C + ++C +F SY+
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYT 858
Query: 2937 CLCTLGWVGRYC 2948
CLC GW G+ C
Sbjct: 859 CLCAPGWQGQRC 870
Score = 52.8 bits (125), Expect = 5e-06
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C + G C++ + CEC + Y+G C+ C ++PC N ATC+ K G CLC G
Sbjct: 427 CEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIG-GFTCLCMPG 485
Query: 2402 RSGPLCTDAINITQ 2415
G C IN Q
Sbjct: 486 FKGVHCELEINECQ 499
Score = 52.4 bits (124), Expect = 7e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF-ASCENNPCGNGATC--VPKSGTDIV 2395
CA C TCI + C CP +G LC +C +NPC GA C P +G +
Sbjct: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNG-QYI 400
Query: 2396 CLCPYGRSGPLCTDAIN 2412
C CP G G CT+ ++
Sbjct: 401 CTCPQGYKGADCTEDVD 417
Score = 52.0 bits (123), Expect = 9e-06
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C N C N G+C F C C P + G C + C + CL+ + CI D Y C
Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCI-DHPNGYEC 556
Query: 2938 LCTLGWVGRYCE 2949
C G+ G CE
Sbjct: 557 QCATGFTGVLCE 568
Score = 50.4 bits (119), Expect = 3e-05
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCV 2387
++ C +P H C++ GTC++ + C+CP+ ++G+ C + C +PC NG TC
Sbjct: 182 DVNECDIP--GH--CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 2388 PKSGTDIVCLCPYGRSGPLC 2407
C C G G C
Sbjct: 238 QTGDFTFECNCLPGFEGSTC 257
Score = 50.1 bits (118), Expect = 4e-05
Identities = 28/72 (38%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C N CR G C F C C +C V+ CL+N C+H + C S Y C
Sbjct: 686 CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-CTGGLS-GYKC 743
Query: 2938 LCTLGWVGRYCE 2949
LC GWVG CE
Sbjct: 744 LCDAGWVGINCE 755
Score = 49.7 bits (117), Expect = 5e-05
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 2610 HASPCSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
H PC +C NGGTC+ C C +G+ G C + S P C G T
Sbjct: 64 HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRP---CLNGGT 120
Query: 2668 CISLPHG-YTCFCPLGTTGIYCE 2689
C L Y C C +G TG C+
Sbjct: 121 CHMLSRDTYECTCQVGFTGKECQ 143
Score = 48.9 bits (115), Expect = 8e-05
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 2876 GTACGYNT---------CRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQS 2925
G C Y+T C NGG C ++ T+ C C + G C + +CL++ C + S
Sbjct: 98 GEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGS 157
Query: 2926 LCIPDQSFSYSCLCTLGWVGRYCE 2949
C + +SC C G+ G+ CE
Sbjct: 158 TCTTVAN-QFSCKCLTGFTGQKCE 180
Score = 48.5 bits (114), Expect = 1e-04
Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 2344 CRNNGTCIS-DNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGT-DIVCLCPY 2400
C N G C++ N +C+CP + G+ CQ CE N C NG TCV ++ C C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 2401 GRSGPLC 2407
G +G C
Sbjct: 95 GFTGEDC 101
Score = 48.5 bits (114), Expect = 1e-04
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 8/103 (7%)
Query: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVP 2388
NC + + CA + C + G C+ C C ++G+ C C +NPC GATC+
Sbjct: 641 NCEINFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCI- 698
Query: 2389 KSGTDIVCLCPYGRSGPLCTDAIN--ITQPRFSGTDAFGYTSF 2429
C+CP G P C +N ++ P G G + +
Sbjct: 699 NGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY 741
Score = 47.8 bits (112), Expect = 2e-04
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQ 2931
+ D C + C+N C F+C C+P + G C ++ C +N C++ C+ D+
Sbjct: 454 EMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCV-DK 512
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
+ CLC G+ G C+
Sbjct: 513 VNRFQCLCPPGFTGPVCQ 530
Score = 47.4 bits (111), Expect = 2e-04
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 5/76 (6%)
Query: 2879 CGYNTCRNGGECTVNGT--TFSCRCLPDWAGNTCNQSVS---CLNNLCLHQSLCIPDQSF 2933
C N C+NGG C +CRC + G C S S ++ CL+ C
Sbjct: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD 127
Query: 2934 SYSCLCTLGWVGRYCE 2949
+Y C C +G+ G+ C+
Sbjct: 128 TYECTCQVGFTGKECQ 143
Score = 47.4 bits (111), Expect = 2e-04
Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 13/90 (14%)
Query: 2606 VGQCHASPCSLMKCGNGGT-CIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
+ +C ++PCS G CI+ C C + + G C V C P C
Sbjct: 1265 INECLSNPCS----SEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVC-----PQMPCLN 1315
Query: 2665 GATCI---SLPHGYTCFCPLGTTGIYCEQA 2691
G TC ++P G+ C CP G +G C+ +
Sbjct: 1316 GGTCAVASNMPDGFICRCPPGFSGARCQSS 1345
Score = 47.0 bits (110), Expect = 3e-04
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 2344 CRNNGTC-ISDNENLFCECPRLYSGKLCQFA-SCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C N GTC + + C C ++GK CQ+ +C ++PC NG+TC + C C G
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVA-NQFSCKCLTG 173
Query: 2402 RSGPLCTDAIN 2412
+G C +N
Sbjct: 174 FTGQKCETDVN 184
Score = 46.6 bits (109), Expect = 4e-04
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Query: 2339 CAHHLCRNNGTCISDNE--NLFCECPRLYSGKLCQFASCE----NNPCGNGATCVPKSGT 2392
C + C+N GTC++ C C ++G+ CQ+++ + PC NG TC S
Sbjct: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD 127
Query: 2393 DIVCLCPYGRSGPLC--TDA 2410
C C G +G C TDA
Sbjct: 128 TYECTCQVGFTGKECQWTDA 147
Score = 46.6 bits (109), Expect = 4e-04
Identities = 30/85 (35%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 2333 NCH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNP-CGNGATCV 2387
NC V C + C+N GTCI + C CP G LC+ C P C NG C+
Sbjct: 1183 NCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM 1242
Query: 2388 PKSGTDIVCLCPYGRSGPLCTDAIN 2412
+ G C C G +G C IN
Sbjct: 1243 DRIG-GYSCRCLPGFAGERCEGDIN 1266
Score = 46.2 bits (108), Expect = 5e-04
Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCI 2928
N+ +CD C + C++G + +++C C P + G C+ + C ++ CL+ CI
Sbjct: 570 NIDNCDPDPCHHGQCQDGID------SYTCICNPGYMGAICSDQIDECYSSPCLNDGRCI 623
Query: 2929 PDQSFSYSCLCTLGWVGRYCE 2949
D Y C C G G CE
Sbjct: 624 -DLVNGYQCNCQPGTSGVNCE 643
Score = 46.2 bits (108), Expect = 5e-04
Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 13/96 (13%)
Query: 2609 CHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC 2668
C ++PC G C++ C C+ G+ G C + C + C +GATC
Sbjct: 649 CASNPCI------HGICMDGINRYSCVCSPGFTGQRCNIDIDEC-----ASNPCRKGATC 697
Query: 2669 ISLPHGYTCFCPLGTTGIYCEQALS--ISDPSFRSN 2702
I+ +G+ C CP G C ++ +S+P N
Sbjct: 698 INGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Score = 45.8 bits (107), Expect = 7e-04
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 2879 CGYNTCRNGGECT--VNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSY 2935
C + C N G C VNG + C C P +G C + C +N C+H +C+ D Y
Sbjct: 611 CYSSPCLNDGRCIDLVNG--YQCNCQPGTSGVNCEINFDDCASNPCIH-GICM-DGINRY 666
Query: 2936 SCLCTLGWVGRYC 2948
SC+C+ G+ G+ C
Sbjct: 667 SCVCSPGFTGQRC 679
Score = 45.4 bits (106), Expect = 9e-04
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 2860 LTEF-GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS-VSCL 2917
LT F G K ++V +CD C++GG C ++ C+C + G C+ V C
Sbjct: 171 LTGFTGQKCETDVNECDIPG----HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCA 226
Query: 2918 NNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+ C++ C F++ C C G+ G CE
Sbjct: 227 PSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE 258
Score = 45.4 bits (106), Expect = 9e-04
Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQ-SFSYSC 2937
C + +C G C +FSC C AG C+ +C++N C +LC + + Y C
Sbjct: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC 401
Query: 2938 LCTLGWVGRYC 2948
C G+ G C
Sbjct: 402 TCPQGYKGADC 412
Score = 45.4 bits (106), Expect = 9e-04
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 7/94 (7%)
Query: 2609 CHASP-CSLMKCGNGGTCIESGTS--VYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
CH C C G C + + C C G+KG+ CTE V C + P C
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNP--CEHA 430
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALS--ISDP 2697
C++ + C C G G CE ++ SDP
Sbjct: 431 GKCVNTDGAFHCECLKGYAGPRCEMDINECHSDP 464
Score = 45.4 bits (106), Expect = 9e-04
Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCL 2938
C C NG +C + + C+C + G C +++ + H C D SY+C+
Sbjct: 536 CSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQC-QDGIDSYTCI 594
Query: 2939 CTLGWVGRYCENK 2951
C G++G C ++
Sbjct: 595 CNPGYMGAICSDQ 607
Score = 44.3 bits (103), Expect = 0.002
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVP 2388
NC V C + C+N GTC + C C + + G CQ C +NPC N TC
Sbjct: 753 NCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFD 812
Query: 2389 K-SGTDIVCLCPY 2400
SG C+ PY
Sbjct: 813 DISGYTCHCVLPY 825
Score = 44.3 bits (103), Expect = 0.002
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
C NGG C++ C C G+ G C ++ C P CI L + Y C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINEC---LSNPCSSEGSLDCIQLTNDYLCV 1291
Query: 2679 CPLGTTGIYCEQALSI 2694
C TG +CE + +
Sbjct: 1292 CRSAFTGRHCETFVDV 1307
Score = 44.3 bits (103), Expect = 0.002
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 2339 CAHHLCRNNGT--CISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSG--T 2392
C + C + G+ CI + C C ++G+ C+ C PC NG TC S
Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
Query: 2393 DIVCLCPYGRSGPLC 2407
+C CP G SG C
Sbjct: 1328 GFICRCPPGFSGARC 1342
Score = 43.9 bits (102), Expect = 0.003
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 24/106 (22%)
Query: 2609 CHASPCSLMKCGNG-GTCIESGTSV-------YCNCTTGWKGSFCTETVSTCDPEHDPP- 2659
C A+P ++C +G C+ G V YC C G+ G +C +H P
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYC---------QHRDPC 68
Query: 2660 --HHCSRGATCI--SLPHGYTCFCPLGTTGIYCEQALSISDPSFRS 2701
+ C G TC+ ++ TC C G TG C+ S S P F S
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ--YSTSHPCFVS 112
Score = 43.9 bits (102), Expect = 0.003
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
Query: 2880 GYNTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSF-SYSC 2937
GY C N G C T + T C+C + G C C N C + C+ +C
Sbjct: 31 GYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATC 90
Query: 2938 LCTLGWVGRYCENKTS 2953
C G+ G C+ TS
Sbjct: 91 RCASGFTGEDCQYSTS 106
Score = 43.9 bits (102), Expect = 0.003
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 2312 LQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTC-ISDN--ENLFCECPRLYSGK 2368
+Q+ N + A G++ E V C C N GTC ++ N + C CP +SG
Sbjct: 1282 IQLTNDYLCVCRSAFTGRHCET-FVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGA 1340
Query: 2369 LCQFASCENNPCGNGATCVPKSGTDIVCLCPYGR 2402
CQ +SC C G CV + + C CP R
Sbjct: 1341 RCQ-SSCGQVKCRKGEQCV-HTASGPRCFCPSPR 1372
Score = 42.4 bits (98), Expect = 0.007
Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCE-NNPCGNGATCVPKSGTDIV 2395
C H C N TC + C+C ++G+ C+ C+ C +G TC+ G+
Sbjct: 148 CLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGS-YQ 206
Query: 2396 CLCPYGRSGPLC 2407
C CP G +G C
Sbjct: 207 CQCPQGFTGQYC 218
Score = 42.4 bits (98), Expect = 0.007
Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 11/70 (15%)
Query: 2614 CSLMKCGNGGTCIESGT---SVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
C M C NGGTC + C C G+ G+ C S+C C +G C+
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVK-----CRKGEQCVH 1359
Query: 2671 LPHGYTCFCP 2680
G CFCP
Sbjct: 1360 TASGPRCFCP 1369
Score = 40.4 bits (93), Expect = 0.028
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
C+ +S C G C + YSC C PPFSG C+ A P +C++ +
Sbjct: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTA---PPSTPPATCLS--Q 1428
Query: 234 NWDEQAYECVCHPPFTGKNCSEIIGQC 260
++A + VC C G C
Sbjct: 1429 YCADKARDGVCDEACNSHACQWDGGDC 1455
Score = 40.0 bits (92), Expect = 0.036
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 17/85 (20%)
Query: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATC 2386
+NI+NC C H G C ++ C C Y G +C Q C ++PC N C
Sbjct: 569 ENIDNCDPDPCHH------GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRC 622
Query: 2387 VPKSGTDIV----CLCPYGRSGPLC 2407
+ D+V C C G SG C
Sbjct: 623 I-----DLVNGYQCNCQPGTSGVNC 642
Score = 39.3 bits (90), Expect = 0.062
Identities = 26/77 (33%), Positives = 31/77 (40%), Gaps = 4/77 (5%)
Query: 2333 NCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKS 2390
N + CA + CR TCI+ C CP C Q C +NPC +G S
Sbjct: 680 NIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLS 739
Query: 2391 GTDIVCLCPYGRSGPLC 2407
G CLC G G C
Sbjct: 740 G--YKCLCDAGWVGINC 754
Score = 38.9 bits (89), Expect = 0.081
Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 5/48 (10%)
Query: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE-KDAGLFFPSFNGNS 2154
C NGGTCH + + ++C C + FTG+ C+ DA L P NG++
Sbjct: 115 CLNGGTCHMLSRDT----YECTCQVGFTGKECQWTDACLSHPCANGST 158
Score = 37.7 bits (86), Expect = 0.18
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C C NGG C G+ ++ C CP +TG+FC +D
Sbjct: 264 CPNHRCQNGGVC-----VDGVNTYNCRCPPQWTGQFCTED 298
Score = 37.4 bits (85), Expect = 0.24
Identities = 29/109 (26%), Positives = 35/109 (32%), Gaps = 34/109 (31%)
Query: 2879 CGYNTCRNGGECTVNGTT---FSCRCLPDWAGNTCNQSV--------------------- 2914
C C NGG C V F CRC P ++G C S
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCF 1367
Query: 2915 ---------SCLNNLCLHQSLCIPD-QSFSYSCLCTLGWVGRYCENKTS 2953
C ++ C H C P Q YSC C + G CE T+
Sbjct: 1368 CPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTA 1416
Score = 35.8 bits (81), Expect = 0.69
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 22/93 (23%)
Query: 2603 GRSVGQCHASPCSLMKCGNGGTCIE--SGTSVYC----NCTTGWKGSFCTETVSTCDPEH 2656
G S +C +S C +KC G C+ SG +C +C +G S C + +C P+
Sbjct: 1336 GFSGARCQSS-CGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPC-QHGGSCHPQR 1393
Query: 2657 DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
PP+ Y+C C +G CE
Sbjct: 1394 QPPY--------------YSCQCAPPFSGSRCE 1412
Score = 34.3 bits (77), Expect = 2.0
Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 13/46 (28%)
Query: 2103 CQQDV--------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
C+ DV C +GGTC + S+QC CP FTG++C+
Sbjct: 179 CETDVNECDIPGHCQHGGTCLNL-----PGSYQCQCPQGFTGQYCD 219
Score = 34.3 bits (77), Expect = 2.0
Identities = 18/43 (41%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 2102 VCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG 2144
VC Q C NGGTC S+ F C CP F+G C+ G
Sbjct: 1307 VCPQMPCLNGGTC--AVASNMPDGFICRCPPGFSGARCQSSCG 1347
Score = 33.9 bits (76), Expect = 2.6
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C C NGGTC +G +F+C+C F G CE++
Sbjct: 225 CAPSPCVNGGTCR----QTGDFTFECNCLPGFEGSTCERN 260
Score = 33.1 bits (74), Expect = 4.4
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 7/59 (11%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAG--LFFPSFNGNSYLELP 2159
CQ + C N G C + FQC CP FTG C+ D P NG ++ P
Sbjct: 498 CQSNPCVNNGQC-----VDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP 551
Score = 33.1 bits (74), Expect = 4.4
Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 11/59 (18%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTT--FSCRCLPDWAGNTC--------NQSVSCLNNLC 2921
DC+ + C + C++GG C +SC+C P ++G+ C +CL+ C
Sbjct: 1373 DCE-SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYC 1430
Score = 32.0 bits (71), Expect = 9.9
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 7/52 (13%)
Query: 2092 SVSPSVAAP--SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
+VS +AA V + +C + G C +++G + C CPL +TG +CE+
Sbjct: 1102 NVSCDIAASRRGVLVEHLCQHSGVC----INAGNTHY-CQCPLGYTGSYCEE 1148
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 563 bits (1450), Expect = e-159
Identities = 354/1172 (30%), Positives = 499/1172 (42%), Gaps = 165/1172 (14%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
C+ G+C ++ S+ +C C P + G+ CQ D C PC G C + + + C
Sbjct: 49 CANGGRC-TQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTAR-FSC 106
Query: 243 VCHPPFTGKNCSEIIGQCQPHVCFHG-NCSNITSNSFICECDEQFSGPFCEVSAKPC-VS 300
C F G +CS + C C HG CS F+C C + G C C V
Sbjct: 107 RCPRGFRGPDCS-LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 165
Query: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVM--CIC 358
G C N+ ++ +CP G + E + PC+NG C + S D+ C C
Sbjct: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC-RQSGDLTYDCAC 224
Query: 359 SPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN 418
P F C+ C N TC Y C C +T + C + +D C+L
Sbjct: 225 LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNA 284
Query: 419 CLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHG-ICQDKGPAQF 477
C N CFN +G VC+ G T C +N+ C V FHG C D+ A F
Sbjct: 285 CHNGGTCFNTLGGHSCVCVNGWTGESC--SQNI-----DDCATAVCFHGATCHDR-VASF 336
Query: 478 EYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICAN 537
+ G G C + DA ++ C EDA +P + + C P T C
Sbjct: 337 YCACPM---GKTGLLCH-LDDA--CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC-- 388
Query: 538 GCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYI 597
++D E C + N C+H C + C C Y
Sbjct: 389 ------DQDVDE----CSI--------------GANPCEHLGRCVNTQGSFLCQCGRGYT 424
Query: 598 GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTT 657
G C +V+ CL + CL C + + CE+D ++C+S+ C NG
Sbjct: 425 GPRCETDVNECLSGPCRN-QATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV 483
Query: 658 STHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPF------ 711
F C GF G+ C++D+DECAS PC+NGA C+DQP Y C+C F
Sbjct: 484 CKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD 543
Query: 712 --------------KVVDG---FSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLS 754
+ VDG FSC C PGY G RCE +D+C C H C DL
Sbjct: 544 RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK 603
Query: 755 YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECD 814
Y C C S G CE ++C NPC C D Y C C G+TG C+ EINEC
Sbjct: 604 YLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECA 662
Query: 815 SDPCMNGGLC----------------------------HES-------TIPGQFVCLCPP 839
S PC GG C HE PG F C+C P
Sbjct: 663 SSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEP 722
Query: 840 LYTGQFCHQ---------------------------------RYNLCDLLH----NPCRN 862
++G C Q + C+LL NPC +
Sbjct: 723 GWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEH 782
Query: 863 NSTCLALVDANQHCICREEFEGKNCEIDVKDCLF-LSCQDYGDCEDMVNNFRCICRPGFS 921
C + C C + ++G C+ DV +C C +G C ++ +F C C G++
Sbjct: 783 GGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT 842
Query: 922 GSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENC 981
G C+ +IN+C PC N G+C D F C+C P + GP C DV++C +PC C
Sbjct: 843 GPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTC 901
Query: 982 VYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCET 1041
+ C C PGY G +CE +L +C C + G C+DG+N ++C C+ G+ G HC+
Sbjct: 902 TDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQH 961
Query: 1042 NANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHG 1100
A+ CLS PCLHG C+ + C+C T QC+ ++ C+ PC N G C ++ G
Sbjct: 962 EADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--G 1019
Query: 1101 FTCICPRGYTGAYCEKSIDNCAEPELN-----SVICLNGGICVDGPGHTFDCRCLPGFSG 1155
C+CP G++G C+ C E +C GG CVD + C C G +G
Sbjct: 1020 AYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY-CVCPEGRTG 1078
Query: 1156 QFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVH-ELCM 1213
CE ++ C + PC HG C ++ GY+C+C PG++G +CE+++ EC C H C+
Sbjct: 1079 SHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCI 1138
Query: 1214 ENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
+ C C PG ++G+LC EI C
Sbjct: 1139 DLVARYLCSCPPG----TLGVLC--EINEDDC 1164
Score = 516 bits (1328), Expect = e-145
Identities = 346/1186 (29%), Positives = 485/1186 (40%), Gaps = 215/1186 (18%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYE 241
C G C ++ TY C C P F G+ C+ +D C C N G+C++ Y
Sbjct: 206 CRNGGTC-RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVD-----GVNTYN 259
Query: 242 CVCHPPFTGKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCV 299
C C P +TG+ C+E + +CQ P+ C +G T C C ++G C + C
Sbjct: 260 CQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCA 319
Query: 300 SLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK--ISNDVMCI 357
+ + + C + +++ CP G + D + S PC C ++ +C
Sbjct: 320 TAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN-PCHEDAICDTNPVNGRAICT 378
Query: 358 CSPIFTDLLCKSIQTSCE--SFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLL 415
C P FT C C + P + C + + C C G+T CE ++ C L
Sbjct: 379 CPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC--L 436
Query: 416 SINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPA 475
S C N+ C + IG+F +C+ G T C ++ C G G+C+D+
Sbjct: 437 SGPCRNQATCLDRIGQFTCICMAGFTGTYCEV--DIDECQSSPCVNG----GVCKDRVNG 490
Query: 476 QFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEIC 535
F GF+GS CQ +D E C
Sbjct: 491 -FSCTCPSGFSGST---CQLDVD------------------------------ECASTPC 516
Query: 536 ANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLS 595
NG C+ + D E R C + G + N D + C H C D I C+C+
Sbjct: 517 RNGAKCVDQPDGYECR--CAEGFEGTLCDRNVDDCSPDPCHHGR-CVDGIASFSCACAPG 573
Query: 596 YIGRLCVVNVDYCLGNHSISVHGLCLAL--SHNCNC-SGLQRYERNICEIDTEDCKSASC 652
Y G C VD C + G CL L + C C SG CE++ +DC S C
Sbjct: 574 YTGTRCESQVDECR-SQPCRHGGKCLDLVDKYLCRCPSGTTGVN---CEVNIDDCASNPC 629
Query: 653 KNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQC----- 707
G + Y C PGF G C ++I+ECAS PC G +C+D + C C
Sbjct: 630 TFGVCRDGINRYDC-VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSL 688
Query: 708 ----VPP--------------FKVVDGFSCLCNPGYVGIRCEQDI--------------- 734
+PP + GF C+C PG+ G RC Q +
Sbjct: 689 PPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGT 748
Query: 735 ------------------------DDCILNACEHNSTCKDLHLSYQ-CVCLSDWEGNFCE 769
C N CEH C+ C C W+G C+
Sbjct: 749 CSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ 808
Query: 770 QESNECK-MNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHEST 828
Q+ +EC PC + CT+L S+ C C G+TG +C ++IN+CD +PC+NGG C +
Sbjct: 809 QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGV 868
Query: 829 IPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE 888
G F C C P + G C + + C L NPC TC V A+ C C + G +CE
Sbjct: 869 --GSFSCSCLPGFAGPRCARDVDEC--LSNPC-GPGTCTDHV-ASFTCTCPPGYGGFHCE 922
Query: 889 IDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTN 948
D+ DC SC + G C D VN+F C+CRPG++G+ C+ E + C S PC + G C
Sbjct: 923 QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP 982
Query: 949 RFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY------------ 996
F C C + GP C+ V+ C PC + CV +T Y CLC PG+
Sbjct: 983 GFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCV-QTGAY-CLCPPGWSGRLCDIRSLPC 1040
Query: 997 ------------------------------------TGINCEINLDECLSEPCLHDGVCI 1020
TG +CE +D CL++PC H G C
Sbjct: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCR 1100
Query: 1021 DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIK 1079
+ Y C+C G+ G +CE + ++C S PC HG C +L+ Y CSC C+I
Sbjct: 1101 GYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEIN 1160
Query: 1080 INDCTSIP-------CMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICL 1132
+DC P C++ G C GF C CP GYTG CE I+ C ++
Sbjct: 1161 EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTR 1220
Query: 1133 NGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHING-----YVCKC 1187
+ C+ PG F C C GFSG C+ ++ C S PC HG C + C C
Sbjct: 1221 D---CLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHC 1277
Query: 1188 -QPGWSGHHCEN------ELECIPNSCVHELCMENEPGSTCLCTPG 1226
QP W G CE EL+C V C + G C C PG
Sbjct: 1278 AQPFW-GPRCERVARSCRELQCP----VGVPCQQTPRGPRCACPPG 1318
Score = 491 bits (1264), Expect = e-138
Identities = 351/1177 (29%), Positives = 481/1177 (40%), Gaps = 205/1177 (17%)
Query: 183 CSGHGKCLSEAWS----KTYSCHCQPPFSGKYCQE-LDACSFKP--CKNNGSCINKRENW 235
C GH +CL+ TY+C C P ++G++C E +D C +P C N G+C N
Sbjct: 240 CPGH-RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGG- 297
Query: 236 DEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA 295
+ CVC +TG++CS+ I C VCFHG + SF C C +G C +
Sbjct: 298 ----HSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD- 352
Query: 296 KPCVSLLFWKRGICPNS--SSAYTYECPKGSSSQNGETDVSEFSLV--PCQNGTDCIKIS 351
CVS + IC + + CP G + + DV E S+ PC++ C+
Sbjct: 353 DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ 412
Query: 352 NDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDH 411
+C C +T C++ C S P RN ATC + C C++GFT CE ID
Sbjct: 413 GSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDE 472
Query: 412 CKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQD 471
C+ S C+N C + + F C G + + C +V C G C D
Sbjct: 473 CQ--SSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL--DVDECASTPCRNGAK----CVD 524
Query: 472 KGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSS----CWFP 527
+ P +E GF EG C +D +C+ D + D +S C
Sbjct: 525 Q-PDGYECRCAEGF---EGTLCDRNVD-------DCSPDPCHHGRCVDGIASFSCACAPG 573
Query: 528 HEGTK----------EICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQH 577
+ GT+ + C +G CL D +Y C G N D N C
Sbjct: 574 YTGTRCESQVDECRSQPCRHGGKCLDLVD--KYLCRCPSGTTGVNCEVNIDDCASNPCTF 631
Query: 578 EAVCKDEINRPRCSCSLSYIGRLCVVNVDYCL----GNHSISVHG--------------- 618
VC+D INR C C + G LC V ++ C G V G
Sbjct: 632 -GVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPP 690
Query: 619 LCLALSHNCN---CSGLQRYE-----RNICE-----------IDTEDCKSASCKNGTTST 659
LCL SH C CS Y+ R +CE + + C+S C+ G T +
Sbjct: 691 LCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCS 750
Query: 660 HLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNY-FCQCVPPFK------ 712
F C PG +G QCE+ + C +PC++G C PG C C ++
Sbjct: 751 SDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQ 809
Query: 713 -------------------VVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHL 753
+ FSC C+ GY G C+QDI+DC N C + +C+D
Sbjct: 810 DVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVG 869
Query: 754 SYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINEC 813
S+ C CL + G C ++ +EC NPC TCTD S+ C C G+ G +C +++ +C
Sbjct: 870 SFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDC 928
Query: 814 DSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN 873
C NGG C + F CLC P YTG C + C L PC + C A
Sbjct: 929 SPSSCFNGGTCVDGV--NSFSCLCRPGYTGAHCQHEADPC--LSRPCLHGGVCSA-AHPG 983
Query: 874 QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECS 933
C C E F G C+ V C CQ+ G C + C+C PG+SG LC+I C
Sbjct: 984 FRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCLCPPGWSGRLCDIRSLPCR 1041
Query: 934 S----------EPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVY 983
+ C+ G CVD + +C C G CE +V+ C PC C
Sbjct: 1042 EAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRG 1101
Query: 984 RTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNA 1043
GY C C PGY G NCE ++DEC S+PC H G CID + Y C C G G CE N
Sbjct: 1102 YMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINE 1161
Query: 1044 NDCLSNP-------CLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCM---NEG 1092
+DC P CLH G C +L+ + C+C T +C+ IN+C S C
Sbjct: 1162 DDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRD 1221
Query: 1093 FCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH----TFDCR 1148
Q GF C+C G++G C+ + C S C +GG C PG TF C
Sbjct: 1222 CLQDPGGGFRCLCHAGFSGPRCQTVLSPC-----ESQPCQHGGQCRPSPGPGGGLTFTCH 1276
Query: 1149 CL--------------------------------------PGFSGQFCE--------INI 1162
C PG SG C +
Sbjct: 1277 CAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASN 1336
Query: 1163 NECSSSPCLHGADCEDHING--YVCKCQPGWSGHHCE 1197
C+++PCLHG C + C C GW+G CE
Sbjct: 1337 ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
Score = 469 bits (1208), Expect = e-131
Identities = 326/1147 (28%), Positives = 464/1147 (40%), Gaps = 207/1147 (18%)
Query: 177 SLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENW 235
S+ + C G+C++ S + C C ++G C+ +++ C PC+N +C+++
Sbjct: 396 SIGANPCEHLGRCVNTQGS--FLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ- 452
Query: 236 DEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSA 295
+ C+C FTG C I +CQ C +G N F C C FSG C++
Sbjct: 453 ----FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV 508
Query: 296 KPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVM 355
C S C + Y C +G + +V + S PC +G C+
Sbjct: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGR-CVDGIASFS 567
Query: 356 CICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLL 415
C C+P +T C+S C S P R+ C Y C C SG T NCE ID C
Sbjct: 568 CACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC--- 624
Query: 416 SINCLNEEWCFNIIGRFKYVCIPG------------CTKNPCW----------------- 446
+ N C + I R+ VC PG C +PC
Sbjct: 625 ASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCP 684
Query: 447 --FLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLA 504
L + L H C HGIC D P F V + G++G + LA
Sbjct: 685 PGSLPPLCLPPSHPCAHEPCSHGICYD-APGGFRCVCEPGWSGPRCSQS---------LA 734
Query: 505 ANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYL 564
+ E + C G +C S D + C G
Sbjct: 735 RDACES----------------------QPCRAGGTCSS--DGMGFHCTCPPGVQGRQ-C 769
Query: 565 ENTTDDQENECQHEAVCKDEINR-PRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLC--L 621
E + N C+H C+ + P CSC + G C +VD C G HG+C L
Sbjct: 770 ELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNL 829
Query: 622 ALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEID 681
A S +C C G Y C+ D DC C NG + G F C+PGF G +C D
Sbjct: 830 AGSFSCTCHG--GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD 887
Query: 682 IDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNA 741
+DEC S+PC G TC D V F+C C PGY G CEQD+ DC ++
Sbjct: 888 VDECLSNPCGPG-TCTDH--------------VASFTCTCPPGYGGFHCEQDLPDCSPSS 932
Query: 742 CEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGW 801
C + TC D S+ C+C + G C+ E++ C PC + C+ + +RC C +
Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF 992
Query: 802 TGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD------- 854
TG C ++ C PC NGG C ++ G + CLCPP ++G+ C R C
Sbjct: 993 TGPQCQTLVDWCSRQPCQNGGRCVQT---GAY-CLCPPGWSGRLCDIRSLPCREAAAQIG 1048
Query: 855 -LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFR 913
L C+ C+ D++ +C+C E G +CE +V CL CQ G C + +
Sbjct: 1049 VRLEQLCQAGGQCVD-EDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYM 1107
Query: 914 CICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKIS 973
C C PG++G CE +++EC+S+PC++ G+C+DL R+ C+C P G CE++ + C
Sbjct: 1108 CECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPG 1167
Query: 974 P-------CLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPC--LHDGVCI-DGI 1023
P CL CV G+ C C PGYTG+ CE +++EC S C H C+ D
Sbjct: 1168 PPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPG 1227
Query: 1024 NHYTCDCKSGFFGTHCETNANDCLSNPCLHG--------------------------RCT 1057
+ C C +GF G C+T + C S PC HG RC
Sbjct: 1228 GGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287
Query: 1058 ELINE---------YPCSCDADGTSTQCKIKIN-----------------DCTSIPCMNE 1091
+ PC G C ++ C + PC++
Sbjct: 1288 RVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHG 1347
Query: 1092 GFCQKS--AHGFTCICPRGYTGAYCE---------------------KSIDNCAEPELNS 1128
G C+ + A F C C +G+TG CE K D + E NS
Sbjct: 1348 GSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNS 1407
Query: 1129 VIC-LNGGICVDGPGHTF-DC---RCLPGFSGQFCEININECSSSPCLH-GADCEDHING 1182
C +GG C G + C +C F+ C+ CSS CL+ DC H G
Sbjct: 1408 PGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCD---PACSSPACLYDNFDC--HAGG 1462
Query: 1183 YVCKCQP 1189
C P
Sbjct: 1463 RERTCNP 1469
Score = 460 bits (1183), Expect = e-128
Identities = 277/981 (28%), Positives = 409/981 (41%), Gaps = 153/981 (15%)
Query: 340 PCQNGTDCIKI-SNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKC----EKDYPC 394
PC NG C ++ S + C+C P + C+ ++ C S P C+ + C
Sbjct: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGPCAGRGVCQSSVVAGTARFSC 106
Query: 395 SCISGFTEKNCEKAIDHCKLLSINCLNEEWC-FNIIGRFKYVCIPGCTKNPCWFLKNVYL 453
C GF +C D C LS C + C GRF C P
Sbjct: 107 RCPRGFRGPDCSLP-DPC--LSSPCAHGARCSVGPDGRFLCSCPP--------------- 148
Query: 454 IHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATY 513
G +G C+ +D + C T
Sbjct: 149 ---------------------------------GYQGRSCRSDVDECR-VGEPCRHGGTC 174
Query: 514 VNDPEDNNSSCWFPHEG----------TKEICANGCSCLSEEDSQEYRYLCFLRWAGNMY 563
+N P C + G C NG +C D Y C + G
Sbjct: 175 LNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT-YDCACLPGFEGQNC 233
Query: 564 LENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYC-LGNHSISVHGLCLA 622
N D + C + C D +N C C + G+ C +VD C L ++ G C
Sbjct: 234 EVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFN 293
Query: 623 LSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDI 682
+C + + C + +DC +A C +G T F+ C G G C +D
Sbjct: 294 TLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD- 352
Query: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL--N 740
D C S+PC A C P N C C PG+ G C+QD+D+C + N
Sbjct: 353 DACVSNPCHEDAICDTNPVN------------GRAICTCPPGFTGGACDQDVDECSIGAN 400
Query: 741 ACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSG 800
CEH C + S+ C C + G CE + NEC PC+N +TC D + C C +G
Sbjct: 401 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAG 460
Query: 801 WTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPC 860
+TG C +I+EC S PC+NGG+C + F C CP ++G C + C PC
Sbjct: 461 FTGTYCEVDIDECQSSPCVNGGVCKDRV--NGFSCTCPSGFSGSTCQLDVDEC--ASTPC 516
Query: 861 RNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGF 920
RN + C+ D + C C E FEG C+ +V DC C +G C D + +F C C PG+
Sbjct: 517 RNGAKCVDQPDGYE-CRCAEGFEGTLCDRNVDDCSPDPCH-HGRCVDGIASFSCACAPGY 574
Query: 921 SGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEEN 980
+G+ CE +++EC S+PC++ G C+DL +++ C C G CE++++ C +PC
Sbjct: 575 TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV- 633
Query: 981 CVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
C + Y+C+C PG+TG C + ++EC S PC G C+DG N + C C G C
Sbjct: 634 CRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL 693
Query: 1041 TNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKI--NDCTSIPCMNEGFCQKSA 1098
++ C PC HG C + + C C+ + +C + + C S PC G C
Sbjct: 694 PPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDG 753
Query: 1099 HGF--------------------------------------TCICPRGYTGAYCEKSIDN 1120
GF C CP+G+ G C++ +D
Sbjct: 754 MGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE 813
Query: 1121 CAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHI 1180
CA P C GIC + G +F C C G++G C+ +IN+C +PCL+G C+D +
Sbjct: 814 CAGP----APCGPHGICTNLAG-SFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGV 868
Query: 1181 NGYVCKCQPGWSGHHCENEL-ECIPNSCVHELCMENEPGSTCLCTPGF------------ 1227
+ C C PG++G C ++ EC+ N C C ++ TC C PG+
Sbjct: 869 GSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDC 928
Query: 1228 --MTCSIGLLCGDEIRRITCL 1246
+C G C D + +CL
Sbjct: 929 SPSSCFNGGTCVDGVNSFSCL 949
Score = 388 bits (997), Expect = e-107
Identities = 209/668 (31%), Positives = 304/668 (45%), Gaps = 109/668 (16%)
Query: 689 PCKNGATCIDQPG-NYFCQCVPPF------------------------KVVDG---FSCL 720
PC NG C P C C P + VV G FSC
Sbjct: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCR 107
Query: 721 C--------------------------------------NPGYVGIRCEQDIDDC-ILNA 741
C PGY G C D+D+C +
Sbjct: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
Query: 742 CEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCT---DLYKSYRCECT 798
C H TC + S++C C + + G CE + C +PC+N TC DL +Y C C
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDL--TYDCACL 225
Query: 799 SGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHN 858
G+ GQNC +++C C+NGG C + + C CPP +TGQFC + + C L N
Sbjct: 226 PGFEGQNCEVNVDDCPGHRCLNGGTCVDGV--NTYNCQCPPEWTGQFCTEDVDECQLQPN 283
Query: 859 PCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRP 918
C N TC + + C+C + G++C ++ DC C C D V +F C C
Sbjct: 284 ACHNGGTCFNTLGGHS-CVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPM 342
Query: 919 GFSGSLCEIEINECSSEPCKNNGTC--VDLTNRFFCNCEPEYHGPFCELDVNKCKI--SP 974
G +G LC ++ + C S PC + C + R C C P + G C+ DV++C I +P
Sbjct: 343 GKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANP 401
Query: 975 CLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGF 1034
C CV + C C GYTG CE +++ECLS PC + C+D I +TC C +GF
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF 461
Query: 1035 FGTHCETNANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGF 1093
GT+CE + ++C S+PC++G C + +N + C+C + + + C++ +++C S PC N
Sbjct: 462 TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAK 521
Query: 1094 CQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF 1153
C G+ C C G+ G C++++D+C+ + G CVDG +F C C PG+
Sbjct: 522 CVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH------GRCVDGIA-SFSCACAPGY 574
Query: 1154 SGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE-NELECIPNSCVHELC 1212
+G CE ++EC S PC HG C D ++ Y+C+C G +G +CE N +C N C +C
Sbjct: 575 TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVC 634
Query: 1213 MENEPGSTCLCTPGF--------------MTCSIGLLCGDEIRRITCLTPIFQRTDPIST 1258
+ C+C PGF C G C D CL P P S
Sbjct: 635 RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCP------PGSL 688
Query: 1259 QTYTIPPS 1266
+PPS
Sbjct: 689 PPLCLPPS 696
Score = 267 bits (683), Expect = 1e-70
Identities = 156/511 (30%), Positives = 221/511 (43%), Gaps = 101/511 (19%)
Query: 814 DSDPCMNGGLCHESTIPG-QFVCLCPPLYTGQFCHQRYNLCDLLHN-PCRNNSTCLALV- 870
D PC NGG C + +P + CLCPP + G+ C L D H+ PC C + V
Sbjct: 45 DGSPCANGGRC--TQLPSREAACLCPPGWVGERC----QLEDPCHSGPCAGRGVCQSSVV 98
Query: 871 --DANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE-DMVNNFRCICRPGFSGSLCEI 927
A C C F G +C + CL C C F C C PG+ G C
Sbjct: 99 AGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 157
Query: 928 EINECS-SEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD 986
+++EC EPC++ GTC++ F C C Y GP CE C SPC + C D
Sbjct: 158 DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD 217
Query: 987 -GYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCK-------------- 1031
Y+C C PG+ G NCE+N+D+C CL+ G C+DG+N Y C C
Sbjct: 218 LTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDE 277
Query: 1032 --------------------------SGFFGTHCETNANDCLSNPCLHG-RCTELINEYP 1064
+G+ G C N +DC + C HG C + + +
Sbjct: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFY 337
Query: 1065 CSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHG--FTCICPRGYTGAYCEKSIDNCA 1122
C+C T C + + C S PC + C + C CP G+TG C++ +D C+
Sbjct: 338 CACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECS 396
Query: 1123 --------------------------------EPELNSVI---CLNGGICVDGPGHTFDC 1147
E ++N + C N C+D G F C
Sbjct: 397 IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ-FTC 455
Query: 1148 RCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECIPNS 1206
C+ GF+G +CE++I+EC SSPC++G C+D +NG+ C C G+SG C+ ++ EC
Sbjct: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTP 515
Query: 1207 CVH-ELCMENEPGSTCLCTPGFMTCSIGLLC 1236
C + C++ G C C GF G LC
Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFE----GTLC 542
Score = 143 bits (360), Expect = 3e-33
Identities = 168/746 (22%), Positives = 253/746 (33%), Gaps = 166/746 (22%)
Query: 171 QQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDACSFKPCKNNGSCI 229
QQ E C HG C + A S +SC C ++G C Q+++ C PC N GSC
Sbjct: 808 QQDVDECAGPAPCGPHGICTNLAGS--FSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ 865
Query: 230 NK-----------------RENWDE---------------QAYECVCHPPFTGKNCSEII 257
+ + DE ++ C C P + G +C + +
Sbjct: 866 DGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL 925
Query: 258 GQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317
C P CF+G NSF C C ++G C+ A PC+S G+C + +
Sbjct: 926 PDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFR 985
Query: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCE-- 375
C + + +T V S PCQNG C++ C+C P ++ LC C
Sbjct: 986 CTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ--TGAYCLCPPGWSGRLCDIRSLPCREA 1043
Query: 376 --SFPLRNNATCK---KC---EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFN 427
+R C+ +C + + C C G T +CE+ +D C L+ C + C
Sbjct: 1044 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC--LAQPCQHGGTCRG 1101
Query: 428 IIGRFKYVCIPG------------CTKNPCWFLKN-VYLIHQHLCYCGVTFHGICQDKGP 474
+G + C+PG C PC + + L+ ++LC C
Sbjct: 1102 YMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCP------------ 1149
Query: 475 AQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEI 534
G+ G C+ ED P D+ C H GT
Sbjct: 1150 -----------PGTLGVLCE------------INEDDCGPGPPLDSGPRCL--HNGTCVD 1184
Query: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRP----RC 590
G +R C + G + + + C H A +D + P RC
Sbjct: 1185 LVGG-----------FRCTCPPGYTGLRCEADINECRSGAC-HAAHTRDCLQDPGGGFRC 1232
Query: 591 SCSLSYIGRLCVVNVDYC------LGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDT 644
C + G C + C G G L+ C+C+ Q + CE
Sbjct: 1233 LCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCA--QPFWGPRCERVA 1290
Query: 645 EDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE--------IDIDECASHPCKNGATC 696
C+ C G C PG G C CA+ PC +G +C
Sbjct: 1291 RSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSC 1350
Query: 697 IDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCE--------QDIDDCILNACEHNSTC 748
P + PF F C C G+ G RCE + C AC+ +
Sbjct: 1351 RPAP-------LAPF-----FRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQ--AKR 1396
Query: 749 KDLHLSYQCVCLS-DWEGNFCE----QESNECKMNPC---KNNSTCTDLYKSYRC----- 795
D +C W+G C +C+ C NNS C S C
Sbjct: 1397 GDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNF 1456
Query: 796 ECTSGWTGQNCSEEINECDSDPCMNG 821
+C +G + C+ + +D +G
Sbjct: 1457 DCHAGGRERTCNPVYEKYCADHFADG 1482
Score = 68.9 bits (167), Expect = 7e-11
Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+ + C +C NGGTC++ + C C W G FCTE V C + P+ C G T
Sbjct: 234 EVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ---PNACHNGGT 290
Query: 2668 CISLPHGYTCFCPLGTTGIYCEQ 2690
C + G++C C G TG C Q
Sbjct: 291 CFNTLGGHSCVCVNGWTGESCSQ 313
Score = 66.2 bits (160), Expect = 5e-10
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 2611 ASPCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCI 2669
A PC+ C NGGTC +SG Y C C G++G C V C P H C G TC+
Sbjct: 198 AVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC-----PGHRCLNGGTCV 252
Query: 2670 SLPHGYTCFCPLGTTGIYCEQ 2690
+ Y C CP TG +C +
Sbjct: 253 DGVNTYNCQCPPEWTGQFCTE 273
Score = 62.8 bits (151), Expect = 5e-09
Identities = 43/152 (28%), Positives = 57/152 (37%), Gaps = 51/152 (33%)
Query: 1122 AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEIN-------------------- 1161
A P L+ C NGG C P C C PG+ G+ C++
Sbjct: 40 APPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVA 99
Query: 1162 --------------------INECSSSPCLHGADCEDHING-YVCKCQPGWSGHHCENEL 1200
+ C SSPC HGA C +G ++C C PG+ G C +++
Sbjct: 100 GTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV 159
Query: 1201 -EC-IPNSCVHELCMENEPGSTCLCTPGFMTC 1230
EC + C H G TCL TPG C
Sbjct: 160 DECRVGEPCRH--------GGTCLNTPGSFRC 183
Score = 62.8 bits (151), Expect = 5e-09
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
Query: 2603 GRSVGQCH--ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
GR+ C PC C +GGTC C C G+ G C + V C +
Sbjct: 1075 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQP---- 1130
Query: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G +CI L Y C CP GT G+ CE
Sbjct: 1131 -CQHGGSCIDLVARYLCSCPPGTLGVLCE 1158
Score = 62.4 bits (150), Expect = 7e-09
Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGTDIVCL 2397
C CR GTC SD C CP G+ C+ S C NPC +G C G VC
Sbjct: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCS 797
Query: 2398 CPYGRSGPLCTDAIN 2412
CP G GP C ++
Sbjct: 798 CPQGWQGPRCQQDVD 812
Score = 61.6 bits (148), Expect = 1e-08
Identities = 33/119 (27%), Positives = 41/119 (34%), Gaps = 36/119 (30%)
Query: 2605 SVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH--- 2661
S Q C+ C NG C++ C C G++G+ C V C P DP HH
Sbjct: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSP--DPCHHGRC 559
Query: 2662 -------------------------------CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G C+ L Y C CP GTTG+ CE
Sbjct: 560 VDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCE 618
Score = 59.7 bits (143), Expect = 4e-08
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 2874 CDGTA--CGYNTCRNGGECTVNGT-TFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIP 2929
C+ A C + CRNGG C +G T+ C CLP + G C +V C + CL+ C+
Sbjct: 194 CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCV- 252
Query: 2930 DQSFSYSCLCTLGWVGRYC 2948
D +Y+C C W G++C
Sbjct: 253 DGVNTYNCQCPPEWTGQFC 271
Score = 59.7 bits (143), Expect = 4e-08
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Query: 2853 INNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ 2912
+N + + G GG+ D D + G N C + G C +F C+C + G C
Sbjct: 371 VNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCET 430
Query: 2913 SVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
V+ CL+ C +Q+ C+ D+ ++C+C G+ G YCE
Sbjct: 431 DVNECLSGPCRNQATCL-DRIGQFTCICMAGFTGTYCE 467
Score = 59.3 bits (142), Expect = 6e-08
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C P + C NGGTC + C C GW G C++ + C C G
Sbjct: 275 VDECQLQPNA---CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC-----ATAVCFHG 326
Query: 2666 ATCISLPHGYTCFCPLGTTGIYC 2688
ATC + C CP+G TG+ C
Sbjct: 327 ATCHDRVASFYCACPMGKTGLLC 349
Score = 58.9 bits (141), Expect = 8e-08
Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH--DP 2658
N V +C + PC +GG+CI+ C+C G G C C P D
Sbjct: 1118 NCEDDVDECASQPCQ-----HGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDS 1172
Query: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C TC+ L G+ C CP G TG+ CE
Sbjct: 1173 GPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
Score = 58.2 bits (139), Expect = 1e-07
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 10/92 (10%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
+ +C +SPC NGG C + C C +G+ GS C V C C G
Sbjct: 470 IDECQSSPCV-----NGGVCKDRVNGFSCTCPSGFSGSTCQLDVDEC-----ASTPCRNG 519
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
A C+ P GY C C G G C++ + P
Sbjct: 520 AKCVDQPDGYECRCAEGFEGTLCDRNVDDCSP 551
Score = 58.2 bits (139), Expect = 1e-07
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDP-----PHHCSRGATC 2668
CS C NGG C+++G YC C GW G C C C G C
Sbjct: 1004 CSRQPCQNGGRCVQTGA--YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
Query: 2669 ISLPHGYTCFCPLGTTGIYCEQ 2690
+ + C CP G TG +CEQ
Sbjct: 1062 VDEDSSHYCVCPEGRTGSHCEQ 1083
Score = 57.8 bits (138), Expect = 2e-07
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 9/82 (10%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV---SCLNNLCLHQSL 2926
NV DC G + C NGG C T++C+C P+W G C + V N C +
Sbjct: 236 NVDDCPG-----HRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGT 290
Query: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
C + +SC+C GW G C
Sbjct: 291 CF-NTLGGHSCVCVNGWTGESC 311
Score = 57.4 bits (137), Expect = 2e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 6/93 (6%)
Query: 2608 QCHA-SPCSLMKCGNGGTCIES-GTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
QC SPC+ C +GG C + G C+C GW+G C + V C P C
Sbjct: 768 QCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAG----PAPCGPH 823
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
C +L ++C C G TG C+Q ++ DP+
Sbjct: 824 GICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN 856
Score = 57.4 bits (137), Expect = 2e-07
Identities = 32/78 (41%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
D D C N C NGG C +FSC CLP +AG C + V CL+N C C D
Sbjct: 847 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTC-TDH 904
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
S++C C G+ G +CE
Sbjct: 905 VASFTCTCPPGYGGFHCE 922
Score = 57.0 bits (136), Expect = 3e-07
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 11/99 (11%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P+ + + C +PC NGG+C + S C+C G+ G C V C
Sbjct: 844 PSCDQDINDCDPNPCL-----NGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC-----LS 893
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
+ C G TC +TC CP G G +CEQ L PS
Sbjct: 894 NPCGPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPS 931
Score = 53.9 bits (128), Expect = 2e-06
Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
D D N C NGG C SC C+ W G +C+Q++ C +C H + C D+
Sbjct: 274 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATC-HDR 332
Query: 2932 SFSYSCLCTLGWVGRYC 2948
S+ C C +G G C
Sbjct: 333 VASFYCACPMGKTGLLC 349
Score = 53.1 bits (126), Expect = 4e-06
Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 2613 PCSLMKCGNGGTC-IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
PC C +G C + C+C G++G C V C C G TC++
Sbjct: 122 PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP----CRHGGTCLNT 177
Query: 2672 PHGYTCFCPLGTTGIYCEQALSISDPS 2698
P + C CP G TG CE PS
Sbjct: 178 PGSFRCQCPAGYTGPLCENPAVPCAPS 204
Score = 53.1 bits (126), Expect = 4e-06
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
CR+ GTC++ + C+CP Y+G LC+ C +PC NG TC C C G
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227
Query: 2402 RSGPLC 2407
G C
Sbjct: 228 FEGQNC 233
Score = 53.1 bits (126), Expect = 4e-06
Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 17/105 (16%)
Query: 2336 VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCE------------NNPCGNG 2383
V WC+ C+N G C+ +C CP +SG+LC S C G
Sbjct: 1001 VDWCSRQPCQNGGRCV--QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAG 1058
Query: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAIN--ITQPRFSGTDAFGY 2426
CV + + C+CP GR+G C ++ + QP G GY
Sbjct: 1059 GQCVDEDSSH-YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY 1102
Score = 52.8 bits (125), Expect = 5e-06
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSF 2933
D C CRNG +C + CRC + G C+++V C + C H C+ D
Sbjct: 507 DVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPC-HHGRCV-DGIA 564
Query: 2934 SYSCLCTLGWVGRYCENK 2951
S+SC C G+ G CE++
Sbjct: 565 SFSCACAPGYTGTRCESQ 582
Score = 52.4 bits (124), Expect = 7e-06
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCL 2922
G + +V +C CG G CT + +F+C C P + G C Q + C + C
Sbjct: 881 GPRCARDVDECLSNPCG------PGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCF 934
Query: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCENK 2951
+ C+ D S+SCLC G+ G +C+++
Sbjct: 935 NGGTCV-DGVNSFSCLCRPGYTGAHCQHE 962
Score = 52.0 bits (123), Expect = 9e-06
Identities = 25/72 (34%), Positives = 28/72 (38%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
AC CR GG C+ +G F C C P G C C N C H C C
Sbjct: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVC 796
Query: 2938 LCTLGWVGRYCE 2949
C GW G C+
Sbjct: 797 SCPQGWQGPRCQ 808
Score = 52.0 bits (123), Expect = 9e-06
Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 5/71 (7%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
C GG C++ +S YC C G GS C + V C + C G TC GY C
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQ-----PCQHGGTCRGYMGGYMCE 1109
Query: 2679 CPLGTTGIYCE 2689
C G G CE
Sbjct: 1110 CLPGYNGDNCE 1120
Score = 51.6 bits (122), Expect = 1e-05
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 2332 ENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC----QFASCENNPCGNGAT 2385
+NC +V C H C N GTC+ C+CP ++G+ C + N C NG T
Sbjct: 231 QNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGT 290
Query: 2386 CVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
C G C+C G +G C+ I+
Sbjct: 291 CFNTLGGH-SCVCVNGWTGESCSQNID 316
Score = 51.6 bits (122), Expect = 1e-05
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 11/94 (11%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P + +C +SPC G GG+C++ C C G C C H+P
Sbjct: 652 PLCNVEINECASSPC-----GEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPC--AHEP- 703
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
CS G C P G+ C C G +G C Q+L+
Sbjct: 704 --CSHGI-CYDAPGGFRCVCEPGWSGPRCSQSLA 734
Score = 51.6 bits (122), Expect = 1e-05
Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
Query: 2613 PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP 2672
PC+ C +G C ++ C C GW G C+++++ E P C G TC S
Sbjct: 698 PCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQP---CRAGGTCSSDG 753
Query: 2673 HGYTCFCPLGTTGIYCE 2689
G+ C CP G G CE
Sbjct: 754 MGFHCTCPPGVQGRQCE 770
Score = 51.2 bits (121), Expect = 2e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCL 2922
G +G S D D G CR+GG C +F C+C + G C N +V C + C
Sbjct: 149 GYQGRSCRSDVDECRVG-EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCR 207
Query: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+ C +Y C C G+ G+ CE
Sbjct: 208 NGGTCRQSGDLTYDCACLPGFEGQNCE 234
Score = 51.2 bits (121), Expect = 2e-05
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
+ D C + C NGG C FSC C ++G+TC V C + C + + C+ DQ
Sbjct: 467 EVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCV-DQ 525
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
Y C C G+ G C+
Sbjct: 526 PDGYECRCAEGFEGTLCD 543
Score = 50.8 bits (120), Expect = 2e-05
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 10/90 (11%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P V +C + PC N TC++ C C G+ G++C + C
Sbjct: 426 PRCETDVNECLSGPCR-----NQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS---- 476
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G C +G++C CP G +G C+
Sbjct: 477 -PCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
Score = 50.8 bits (120), Expect = 2e-05
Identities = 34/114 (29%), Positives = 42/114 (36%), Gaps = 16/114 (14%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVC 2396
C C N G C C CP +SG CQ C + PC NGA CV + C
Sbjct: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQP-DGYEC 531
Query: 2397 LCPYGRSGPLCTDAINITQP-------------RFSGTDAFGYTSFLAYSRISD 2437
C G G LC ++ P FS A GYT S++ +
Sbjct: 532 RCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDE 585
Score = 50.8 bits (120), Expect = 2e-05
Identities = 28/78 (35%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C C GGTC G +C C G +G C E +S C P+ C G C S P
Sbjct: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQC-ELLSPC-----TPNPCEHGGRCESAPG 791
Query: 2674 GY-TCFCPLGTTGIYCEQ 2690
C CP G G C+Q
Sbjct: 792 QLPVCSCPQGWQGPRCQQ 809
Score = 50.4 bits (119), Expect = 3e-05
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 5/76 (6%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
CS C NGGTC++ S C C G+ G+ C C C G C +
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC-----LSRPCLHGGVCSAAHP 982
Query: 2674 GYTCFCPLGTTGIYCE 2689
G+ C C TG C+
Sbjct: 983 GFRCTCLESFTGPQCQ 998
Score = 50.1 bits (118), Expect = 4e-05
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C + G C++ + C+C R Y+G C+ C + PC N ATC+ + G C+C G
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIG-QFTCICMAG 460
Query: 2402 RSGPLC 2407
+G C
Sbjct: 461 FTGTYC 466
Score = 50.1 bits (118), Expect = 4e-05
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
C ++C NGG C +FSC C P + G C +++ CL+ CLH +C + C
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP-GFRC 986
Query: 2938 LCTLGWVGRYCE 2949
C + G C+
Sbjct: 987 TCLESFTGPQCQ 998
Score = 50.1 bits (118), Expect = 4e-05
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 14/84 (16%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC----------LNNLCLHQSLC 2927
C C+NGG C G C C P W+G C+ +S+ C L LC C
Sbjct: 1004 CSRQPCQNGGRCVQTGAY--CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
Query: 2928 IPDQSFSYSCLCTLGWVGRYCENK 2951
+ D+ S+ C+C G G +CE +
Sbjct: 1062 V-DEDSSHYCVCPEGRTGSHCEQE 1084
Score = 49.7 bits (117), Expect = 5e-05
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 2315 NNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--F 2372
++ + + E R G + E V C C++ GTC CEC Y+G C+
Sbjct: 1065 DSSHYCVCPEGRTGSHCEQ-EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV 1123
Query: 2373 ASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
C + PC +G +C+ +C CP G G LC
Sbjct: 1124 DECASQPCQHGGSCIDLVAR-YLCSCPPGTLGVLC 1157
Score = 48.9 bits (115), Expect = 8e-05
Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLF-CECPRLYSGKLCQ--FASCENNPCGNGA 2384
G EN VP CA CRN GTC + + C C + G+ C+ C + C NG
Sbjct: 191 GPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGG 249
Query: 2385 TCVPKSGTDIVCLCPYGRSGPLCTDAINITQ 2415
TCV T C CP +G CT+ ++ Q
Sbjct: 250 TCVDGVNT-YNCQCPPEWTGQFCTEDVDECQ 279
Score = 48.9 bits (115), Expect = 8e-05
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 12/88 (13%)
Query: 2604 RSVGQCH--ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH 2661
+ V +C A+PC + G C+ + S C C G+ G C V+ C
Sbjct: 390 QDVDECSIGANPCEHL-----GRCVNTQGSFLCQCGRGYTGPRCETDVNEC-----LSGP 439
Query: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C ATC+ +TC C G TG YCE
Sbjct: 440 CRNQATCLDRIGQFTCICMAGFTGTYCE 467
Score = 48.1 bits (113), Expect = 1e-04
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C C++GG C + C CLP + G+ C V C + C H CI D Y C
Sbjct: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCI-DLVARYLC 1146
Query: 2938 LCTLGWVGRYCE 2949
C G +G CE
Sbjct: 1147 SCPPGTLGVLCE 1158
Score = 47.8 bits (112), Expect = 2e-04
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
C CRN TC+ C C ++G C+ C+++PC NG C + C
Sbjct: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRV-NGFSC 493
Query: 2397 LCPYGRSGPLC 2407
CP G SG C
Sbjct: 494 TCPSGFSGSTC 504
Score = 47.8 bits (112), Expect = 2e-04
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 8/81 (9%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCI 2928
NV DC C + C +G +FSC C P + G C V C + C H C+
Sbjct: 545 NVDDCSPDPCHHGRCVDGI------ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCL 598
Query: 2929 PDQSFSYSCLCTLGWVGRYCE 2949
D Y C C G G CE
Sbjct: 599 -DLVDKYLCRCPSGTTGVNCE 618
Score = 47.4 bits (111), Expect = 2e-04
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 2332 ENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF-ASCENNPCGNGATC-- 2386
E+C ++ CA +C + TC + +C CP +G LC +C +NPC A C
Sbjct: 309 ESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDT 368
Query: 2387 VPKSGTDIVCLCPYGRSGPLCTDAIN 2412
P +G +C CP G +G C ++
Sbjct: 369 NPVNGR-AICTCPPGFTGGACDQDVD 393
Score = 47.0 bits (110), Expect = 3e-04
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C C +GG C+ F C CL + G C V C C + C+ ++ C
Sbjct: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY---C 1022
Query: 2938 LCTLGWVGRYCE 2949
LC GW GR C+
Sbjct: 1023 LCPPGWSGRLCD 1034
Score = 46.2 bits (108), Expect = 5e-04
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 27/130 (20%)
Query: 2304 GFRGCILDLQVNNKEFFIIDEARHGKNIENC------------------HVPWCAHHLCR 2345
GF G + D V++ D HG+ ++ V C CR
Sbjct: 536 GFEGTLCDRNVDDCS---PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCR 592
Query: 2346 NNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTD-IVCLCPYGR 2402
+ G C+ + C CP +G C+ C +NPC G V + G + C+C G
Sbjct: 593 HGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG---VCRDGINRYDCVCQPGF 649
Query: 2403 SGPLCTDAIN 2412
+GPLC IN
Sbjct: 650 TGPLCNVEIN 659
Score = 46.2 bits (108), Expect = 5e-04
Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
G + +V +C G A C G CT +FSC C + G +C+Q ++ C N CL
Sbjct: 804 GPRCQQDVDECAGPA----PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCL 859
Query: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYC 2948
+ C D S+SC C G+ G C
Sbjct: 860 NGGSC-QDGVGSFSCSCLPGFAGPRC 884
Score = 45.8 bits (107), Expect = 7e-04
Identities = 32/100 (32%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 2324 EARHGKNIENCH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP-- 2379
E G N +NC V CA C++ G+CI C CP G LC+ + P
Sbjct: 1109 ECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGP 1168
Query: 2380 -------CGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
C + TCV G C CP G +G C IN
Sbjct: 1169 PLDSGPRCLHNGTCVDLVG-GFRCTCPPGYTGLRCEADIN 1207
Score = 45.8 bits (107), Expect = 7e-04
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 12/95 (12%)
Query: 2601 NAGRSVGQCHA--SPCSLMKCGNGGTCIES-----GTSVYCNCTTGWKGSFCTETVSTCD 2653
+AG S +C SPC C +GG C S G + C+C + G C +C
Sbjct: 1235 HAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCR 1294
Query: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYC 2688
C G C P G C CP G +G C
Sbjct: 1295 ELQ-----CPVGVPCQQTPRGPRCACPPGLSGPSC 1324
Score = 45.4 bits (106), Expect = 9e-04
Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 7/82 (8%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Q A PC C +GG C + C C + G C V C + C G
Sbjct: 960 QHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQ-----PCQNGGR 1014
Query: 2668 CISLPHGYTCFCPLGTTGIYCE 2689
C+ G C CP G +G C+
Sbjct: 1015 CVQT--GAYCLCPPGWSGRLCD 1034
Score = 45.4 bits (106), Expect = 9e-04
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGAT-------CVPKSGTDIVC 2396
C +NGTC+ C CP Y+G C+ + N C +GA C+ G C
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCE---ADINECRSGACHAAHTRDCLQDPGGGFRC 1232
Query: 2397 LCPYGRSGPLCTDAIN 2412
LC G SGP C ++
Sbjct: 1233 LCHAGFSGPRCQTVLS 1248
Score = 45.1 bits (105), Expect = 0.001
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 4/76 (5%)
Query: 2879 CGYNTCRNGGEC---TVNGTT-FSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFS 2934
C C G C V GT FSCRC + G C+ CL++ C H + C
Sbjct: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGR 141
Query: 2935 YSCLCTLGWVGRYCEN 2950
+ C C G+ GR C +
Sbjct: 142 FLCSCPPGYQGRSCRS 157
Score = 44.7 bits (104), Expect = 0.001
Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 9/92 (9%)
Query: 2339 CAHHLCRNNGTC----ISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGTD 2393
C C G C ++ C CPR + G C C ++PC +GA C
Sbjct: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGR 141
Query: 2394 IVCLCPYGRSGPLC---TDAINITQP-RFSGT 2421
+C CP G G C D + +P R GT
Sbjct: 142 FLCSCPPGYQGRSCRSDVDECRVGEPCRHGGT 173
Score = 44.7 bits (104), Expect = 0.001
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 2343 LCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVCLCPY 2400
LC+ G C+ ++ + +C CP +G C + C PC +G TC G +C C
Sbjct: 1054 LCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMG-GYMCECLP 1112
Query: 2401 GRSGPLCTDAIN 2412
G +G C D ++
Sbjct: 1113 GYNGDNCEDDVD 1124
Score = 44.3 bits (103), Expect = 0.002
Identities = 36/142 (25%), Positives = 54/142 (38%), Gaps = 19/142 (13%)
Query: 2826 VSSLNLVNPMAIENEPVGFQG--CIRQV---------------IINNQELQLTEFGAKGG 2868
+ N VN AI P GF G C + V +N Q L + G
Sbjct: 365 ICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT 424
Query: 2869 SNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLC 2927
+ D C CRN C F+C C+ + G C + C ++ C++ +C
Sbjct: 425 GPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC 484
Query: 2928 IPDQSFSYSCLCTLGWVGRYCE 2949
D+ +SC C G+ G C+
Sbjct: 485 -KDRVNGFSCTCPSGFSGSTCQ 505
Score = 43.9 bits (102), Expect = 0.003
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Query: 2879 CGYNTCRNGGECTVNGT-TFSCRCLPDWAGNTCNQSVS-C-LNNLCLHQSLCIPDQSFSY 2935
C + C +G C+V F C C P + G +C V C + C H C+ S+
Sbjct: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPG-SF 181
Query: 2936 SCLCTLGWVGRYCEN 2950
C C G+ G CEN
Sbjct: 182 RCQCPAGYTGPLCEN 196
Score = 43.9 bits (102), Expect = 0.003
Identities = 21/88 (23%), Positives = 35/88 (39%), Gaps = 11/88 (12%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
N ++ C ++PC+ G C + C C G+ G C ++ C
Sbjct: 616 NCEVNIDDCASNPCTF------GVCRDGINRYDCVCQPGFTGPLCNVEINEC-----ASS 664
Query: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYC 2688
C G +C+ +G+ C CP G+ C
Sbjct: 665 PCGEGGSCVDGENGFRCLCPPGSLPPLC 692
Score = 43.9 bits (102), Expect = 0.003
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA----SCENNPCGNGATCVPKSGTDI 2394
CAH C ++G C C C +SG C + +CE+ PC G TC G
Sbjct: 699 CAHEPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTC-SSDGMGF 756
Query: 2395 VCLCPYGRSGPLC 2407
C CP G G C
Sbjct: 757 HCTCPPGVQGRQC 769
Score = 43.9 bits (102), Expect = 0.003
Identities = 30/112 (26%), Positives = 36/112 (32%), Gaps = 43/112 (38%)
Query: 2336 VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--------------------- 2374
+P C+ C N GTC+ + C C Y+G CQ +
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Query: 2375 -------------------CENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
C PC NG CV T CLCP G SG LC
Sbjct: 985 RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ---TGAYCLCPPGWSGRLC 1033
Score = 42.7 bits (99), Expect = 0.006
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
N+ DC C + CR+G +N + C C P + G CN ++ C ++ C C+
Sbjct: 620 NIDDCASNPCTFGVCRDG----IN--RYDCVCQPGFTGPLCNVEINECASSPCGEGGSCV 673
Query: 2929 PDQSFSYSCLCTLGWVGRYC 2948
D + CLC G + C
Sbjct: 674 -DGENGFRCLCPPGSLPPLC 692
Score = 42.7 bits (99), Expect = 0.006
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 2333 NCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKS 2390
N + CA C G+C+ C CP LC S C + PC +G C
Sbjct: 655 NVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAP 713
Query: 2391 GTDIVCLCPYGRSGPLCTDAI 2411
G C+C G SGP C+ ++
Sbjct: 714 G-GFRCVCEPGWSGPRCSQSL 733
Score = 42.4 bits (98), Expect = 0.007
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
Query: 2884 CRNGGECT-VNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLC---IPDQSFSYSCLC 2939
C NGG CT + +C C P W G C C + C + +C + + +SC C
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 2940 TLGWVGRYC 2948
G+ G C
Sbjct: 109 PRGFRGPDC 117
Score = 42.0 bits (97), Expect = 0.010
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV---SCLNNLCLHQSLCIPDQSFSY 2935
C + C +G C F C C P W+G C+QS+ +C + C C D +
Sbjct: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD-GMGF 756
Query: 2936 SCLCTLGWVGRYCE 2949
C C G GR CE
Sbjct: 757 HCTCPPGVQGRQCE 770
Score = 42.0 bits (97), Expect = 0.010
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C +G C + + C C Y+G C C+ NPC NG +C G+ C C G
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGS-FSCSCLPG 878
Query: 2402 RSGPLCTDAIN--ITQPRFSGTDAFGYTSFLAYSRISDISFHYE 2443
+GP C ++ ++ P GT SF FH E
Sbjct: 879 FAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCE 922
Score = 42.0 bits (97), Expect = 0.010
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP-HGYT 2676
+C + GTC++ C C G+ G C ++ C H + C+ P G+
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC---RSGACHAAHTRDCLQDPGGGFR 1231
Query: 2677 CFCPLGTTGIYCEQALS 2693
C C G +G C+ LS
Sbjct: 1232 CLCHAGFSGPRCQTVLS 1248
Score = 41.2 bits (95), Expect = 0.016
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 2328 GKNIENCHVP-WCAHHLCRNNGTCISD--NENLFCECPRLYSGKLCQF----ASCENNPC 2380
GK CH+ C + C + C ++ N C CP ++G C S NPC
Sbjct: 343 GKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPC 402
Query: 2381 GNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
+ CV G+ +C C G +GP C +N
Sbjct: 403 EHLGRCVNTQGS-FLCQCGRGYTGPRCETDVN 433
Score = 40.8 bits (94), Expect = 0.021
Identities = 30/101 (29%), Positives = 38/101 (37%), Gaps = 7/101 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
C + C N G+C + C C ++G C C +NPCG G TC + C
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVAS-FTC 910
Query: 2397 LCPYGRSGPLCTDAINITQPRF---SGTDAFGYTSFLAYSR 2434
CP G G C + P GT G SF R
Sbjct: 911 TCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCR 951
Score = 40.8 bits (94), Expect = 0.021
Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 9/77 (11%)
Query: 2886 NGGECTVNGTT------FSCRCLPDWAGNTCNQSVS-CLNNLC--LHQSLCIPDQSFSYS 2936
+G C NGT F C C P + G C ++ C + C H C+ D +
Sbjct: 1172 SGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFR 1231
Query: 2937 CLCTLGWVGRYCENKTS 2953
CLC G+ G C+ S
Sbjct: 1232 CLCHAGFSGPRCQTVLS 1248
Score = 40.0 bits (92), Expect = 0.036
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
C+ GG+C ++ C C G+ C Q V CL C H C Y C C G
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTC-RGYMGGYMCECLPG 1113
Query: 2943 WVGRYCEN 2950
+ G CE+
Sbjct: 1114 YNGDNCED 1121
Score = 39.3 bits (90), Expect = 0.062
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C CR+GG+C + CRC G C ++ C +N C +C D Y C
Sbjct: 586 CRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTF-GVC-RDGINRYDC 643
Query: 2938 LCTLGWVGRYC 2948
+C G+ G C
Sbjct: 644 VCQPGFTGPLC 654
Score = 39.3 bits (90), Expect = 0.062
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 2879 CGYNTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNL-CLHQSLCIPDQSFSY 2935
C N C +GG C + G C C W G C Q V C C +C + + S+
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGIC-TNLAGSF 833
Query: 2936 SCLCTLGWVGRYCE 2949
SC C G+ G C+
Sbjct: 834 SCTCHGGYTGPSCD 847
Score = 38.9 bits (89), Expect = 0.081
Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 11/83 (13%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C + PC +GG C++ C C +G G C + C + C+ G
Sbjct: 583 VDECRSQPCR-----HGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC-----ASNPCTFG 632
Query: 2666 ATCISLPHGYTCFCPLGTTGIYC 2688
C + Y C C G TG C
Sbjct: 633 -VCRDGINRYDCVCQPGFTGPLC 654
Score = 38.5 bits (88), Expect = 0.11
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C C NGGTC G+ ++ C CP +TG+FC +D
Sbjct: 240 CPGHRCLNGGTC-----VDGVNTYNCQCPPEWTGQFCTED 274
Score = 38.5 bits (88), Expect = 0.11
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 3/71 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
C + C GG C F C C P C S C + C H +C D + C
Sbjct: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSH-GICY-DAPGGFRC 718
Query: 2938 LCTLGWVGRYC 2948
+C GW G C
Sbjct: 719 VCEPGWSGPRC 729
Score = 38.5 bits (88), Expect = 0.11
Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 10/90 (11%)
Query: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC-------LNN 2919
G N D D C C++GG C + C C P G C C
Sbjct: 1116 GDNCED-DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174
Query: 2920 LCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
CLH C+ D + C C G+ G CE
Sbjct: 1175 RCLHNGTCV-DLVGGFRCTCPPGYTGLRCE 1203
Score = 37.0 bits (84), Expect = 0.31
Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLH 2923
G N+ DC TA C +G C +F C C G C+ +C++N C
Sbjct: 308 GESCSQNIDDC-ATA----VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHE 362
Query: 2924 QSLCIPDQSFSYS-CLCTLGWVGRYCE 2949
++C + + C C G+ G C+
Sbjct: 363 DAICDTNPVNGRAICTCPPGFTGGACD 389
Score = 37.0 bits (84), Expect = 0.31
Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 2350 CISDNENLF-CECPRLYSGKLCQ--FASCENNPCGNGATCVPK----SGTDIVCLCPYGR 2402
C+ D F C C +SG CQ + CE+ PC +G C P G C C
Sbjct: 1222 CLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPF 1281
Query: 2403 SGPLC 2407
GP C
Sbjct: 1282 WGPRC 1286
Score = 36.6 bits (83), Expect = 0.40
Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 6/53 (11%)
Query: 2090 WTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
WT S S C VC +G TCH + SF C CP+ TG C D
Sbjct: 306 WTGESCSQNIDD-CATAVCFHGATCH-----DRVASFYCACPMGKTGLLCHLD 352
Score = 36.6 bits (83), Expect = 0.40
Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 10/82 (12%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ---------SVSCLNNLCLHQSLCI 2928
+C C G C C C P +G +C + SC CLH C
Sbjct: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1351
Query: 2929 PDQSFSY-SCLCTLGWVGRYCE 2949
P + C C GW G CE
Sbjct: 1352 PAPLAPFFRCACAQGWTGPRCE 1373
Score = 35.4 bits (80), Expect = 0.90
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 2592 GLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVY--CNCTTGWKGSFCTETV 2649
GL P G G +AS C+ C +GG+C + + + C C GW G C
Sbjct: 1318 GLSGPSCRSFPGSPPGASNAS-CAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPA 1376
Query: 2650 STCDPEHDPPHHCSRGA 2666
+ + +P C R A
Sbjct: 1377 AAPEVSEEP--RCPRAA 1391
Score = 35.0 bits (79), Expect = 1.2
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 5/41 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDA 2143
C C NGGTC G+ SF C C +TG C+ +A
Sbjct: 928 CSPSSCFNGGTC-----VDGVNSFSCLCRPGYTGAHCQHEA 963
Score = 34.7 bits (78), Expect = 1.5
Identities = 15/40 (37%), Positives = 18/40 (45%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
CQ C NGG C + F C CP F+G C+ D
Sbjct: 473 CQSSPCVNGGVC-----KDRVNGFSCTCPSGFSGSTCQLD 507
Score = 34.3 bits (77), Expect = 2.0
Identities = 17/42 (40%), Positives = 19/42 (45%), Gaps = 5/42 (11%)
Query: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
A C+ C GGTC SS + F C CP GR CE
Sbjct: 734 ARDACESQPCRAGGTC-----SSDGMGFHCTCPPGVQGRQCE 770
Score = 33.9 bits (76), Expect = 2.6
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 13/55 (23%)
Query: 2103 CQQDV--------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPS 2149
C+ DV C +GGTC + G SF+C CP +TG CE A PS
Sbjct: 155 CRSDVDECRVGEPCRHGGTC---LNTPG--SFRCQCPAGYTGPLCENPAVPCAPS 204
Score = 33.5 bits (75), Expect = 3.4
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 5/47 (10%)
Query: 2095 PSVAAPSV-CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
P P+V C C NGGTC SG +++ C C F G+ CE
Sbjct: 192 PLCENPAVPCAPSPCRNGGTCR----QSGDLTYDCACLPGFEGQNCE 234
Score = 33.5 bits (75), Expect = 3.4
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 11/60 (18%)
Query: 2359 CECPRLYSGKLCQF----------ASCENNPCGNGATCVPKSGTDIV-CLCPYGRSGPLC 2407
C CP SG C+ ASC PC +G +C P C C G +GP C
Sbjct: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC 1372
Score = 33.1 bits (74), Expect = 4.4
Identities = 12/32 (37%), Positives = 15/32 (46%)
Query: 2376 ENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
+ +PC NG C + CLCP G G C
Sbjct: 45 DGSPCANGGRCTQLPSREAACLCPPGWVGERC 76
Score = 33.1 bits (74), Expect = 4.4
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C + C NGG+C G+ SF C C F G C +D
Sbjct: 853 CDPNPCLNGGSC-----QDGVGSFSCSCLPGFAGPRCARD 887
Score = 33.1 bits (74), Expect = 4.4
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 14/81 (17%)
Query: 2085 GVDTMWTSVSPSVAAPSVCQQDV--CHNG----GTCHAIFLSSGIVSFQCDCPLHFTGRF 2138
GV + S P A P C +DV C + GTC + + SF C CP + G
Sbjct: 867 GVGSFSCSCLPGFAGPR-CARDVDECLSNPCGPGTC-----TDHVASFTCTCPPGYGGFH 920
Query: 2139 CEKDAGLFFPS--FNGNSYLE 2157
CE+D PS FNG + ++
Sbjct: 921 CEQDLPDCSPSSCFNGGTCVD 941
Score = 32.3 bits (72), Expect = 7.6
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDA 2143
S C+ C +GG C G ++F C C F G CE+ A
Sbjct: 1248 SPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVA 1290
Score = 32.3 bits (72), Expect = 7.6
Identities = 21/76 (27%), Positives = 28/76 (36%), Gaps = 8/76 (10%)
Query: 2339 CAHHLCRNNGTCISD-----NENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSG 2391
C C++ G C C C + + G C+ SC C G C ++
Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPC-QQTP 1308
Query: 2392 TDIVCLCPYGRSGPLC 2407
C CP G SGP C
Sbjct: 1309 RGPRCACPPGLSGPSC 1324
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 485 bits (1248), Expect = e-136
Identities = 331/1134 (29%), Positives = 456/1134 (40%), Gaps = 169/1134 (14%)
Query: 157 SPCPLGLRLNVTVKQQF----CQESLSS----EFCSGHGKCLSEAWSKTYSCHCQPPFSG 208
SP PL T F CQ L FCS G+C +A + C C P ++G
Sbjct: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTG 151
Query: 209 KYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC--QPHVCF 266
+ CQ D CS PC N G C+ +C C P F G C + +C P C
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQ-----IQCHCPPGFEGHACERDVNECFQDPGPCP 206
Query: 267 HGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSS 326
G + T SF C C GP CE+ A PC P+G S
Sbjct: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCP---------------------PRGCS- 244
Query: 327 QNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCK 386
NG T CQ + K S +C+C P F C+ +C S +N TC+
Sbjct: 245 -NGGT---------CQLMPE--KDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQ 292
Query: 387 KCEKDYPCSCISGFTEKNCEKAIDHCKLLSI-NCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
Y C C +T +C + +D C+ +C N C N G F VC+ G C
Sbjct: 293 DGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSC 352
Query: 446 WFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAG---SEGEKCQGVIDAYFF 502
+N+ C G T C D+ F + G G + C
Sbjct: 353 E--ENLDDCIAATCAPGST----CIDR-VGSFSCLCPPGRTGLLCHLEDMC--------- 396
Query: 503 LAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS---CLSEEDSQEYRYLCFLRWA 559
L+ C DA +P ++ C +C G S C + D C +
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLC---------LCQPGYSGPTCHQDLDE------CLMAQQ 441
Query: 560 GNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGL 619
G + C+H C + C C Y G C + + CL +
Sbjct: 442 G-----------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL-SQPCHPGST 489
Query: 620 CLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE 679
CL L +C E +CE++T +C SA C N L F C+PGF GT+CE
Sbjct: 490 CLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCE 549
Query: 680 IDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
DIDEC S PC NG C DQPG + C+C+P G+ G RC+ ++D+C+
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLP--------------GFEGPRCQTEVDECLS 595
Query: 740 NACEHNSTCKDLHLSYQCVCLSDWEGNFCE---------QESNECKMNPCKNNSTCTD-- 788
+ C ++C DL ++ C+C S + G CE Q CK K N C D
Sbjct: 596 DPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGS 655
Query: 789 ---------------LYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQF 833
+ C C GWTG C E+ C S PC +GG C+ P +
Sbjct: 656 PGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ--PSGY 713
Query: 834 VCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKD 893
C CP YTG C + C PC N +C +C C G C+
Sbjct: 714 NCTCPTGYTGPTCSEEMTACH--SGPCLNGGSCNPS-PGGYYCTCPPSHTGPQCQTSTDY 770
Query: 894 CLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEIN-ECSSEPCKNNGTCVDLTNRFFC 952
C+ C + G C + F C+C GF G CE ++ C+ PC+N TC D C
Sbjct: 771 CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830
Query: 953 NCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDEC---- 1008
C Y G C+ ++ C PC +C+ ++CLC G+TG C + L C
Sbjct: 831 LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA 890
Query: 1009 ------LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELIN 1061
+S C + G+C+D Y C C GF G+ C+ + N C S PC +G C +
Sbjct: 891 LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS 950
Query: 1062 EYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNC 1121
Y C C C +++ C S PC N G C GF C CP G+ G CE +D C
Sbjct: 951 GYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC 1010
Query: 1122 AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHIN 1181
+ + G + F C+CLPG +GQ+CE+ I+ C S PC HG CE
Sbjct: 1011 LDQPCHPT----GTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAG 1066
Query: 1182 ---GYVCKCQPGWSGHHCENEL-ECIPNSCVH-ELCMEN-EPG--STCLCTPGF 1227
G++C C G+ G C + C + C H LC+ + +PG C C G+
Sbjct: 1067 SPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY 1120
Score = 470 bits (1209), Expect = e-131
Identities = 298/1003 (29%), Positives = 431/1003 (42%), Gaps = 131/1003 (13%)
Query: 340 PCQNGTDCIKIS-NDVMCICSPIFTDLLCKSIQTSCESFPL-RNNATCKKC--------- 388
PC NG C+ +S C C+P F C+ C++ L +N +C+
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ-FPDPCQNAQLCQNGGSCQALLPAPLGLPS 92
Query: 389 -----EKDYPCSCISGFTEKNCE-KAIDHCKLLSINCLNEEWC-FNIIGRFKYVCIPGCT 441
+ C+C+ GFT + C+ K D C C C GR + C+PG T
Sbjct: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCP--PSFCSKRGRCHIQASGRPQCSCMPGWT 150
Query: 442 KNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYF 501
C + C G G+C P Q + GF EG C+ ++ F
Sbjct: 151 GEQCQLRD---FCSANPCVNG----GVCLATYP-QIQCHCPPGF---EGHACERDVNECF 199
Query: 502 FLAANCTEDATYVNDPEDNNSSCWFPHEGTK----------EICANG--CSCLSEEDSQE 549
C + + N C EG + C+NG C + E+DS
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF 259
Query: 550 YRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYC- 608
+ LC + G N + ++CQ+ C+D ++ C C ++ G C +VD C
Sbjct: 260 HLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE 319
Query: 609 -LGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFR 667
G G C + + +C + + CE + +DC +A+C G+T G F
Sbjct: 320 TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC 379
Query: 668 KCVPGFKGTQCEIDIDECASHPCKNGATCIDQP--GNYFCQCVPPFK------------- 712
C PG G C ++ D C S PC A C P G+ C C P +
Sbjct: 380 LCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLM 438
Query: 713 ----------------VVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQ 756
F+CLC PGY G RCE D ++C+ C STC DL ++
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH 498
Query: 757 CVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD 816
C+C EG CE E+NEC PC N++ C DL ++C C G++G C E+I+EC S
Sbjct: 499 CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSS 558
Query: 817 PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHC 876
PC NGG C + PG F C C P + G C + C L +PC ++CL L A C
Sbjct: 559 PCANGGQCQDQ--PGAFHCKCLPGFEGPRCQTEVDEC--LSDPCPVGASCLDLPGAF-FC 613
Query: 877 ICREEFEGKNCEI---------------DVKDCLFLSCQD---------------YGDCE 906
+C F G+ CE+ D KD C D +G C+
Sbjct: 614 LCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQ 673
Query: 907 DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELD 966
C+C G++G CE E+ C S PC + GTC + + C C Y GP C +
Sbjct: 674 ----RSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEE 729
Query: 967 VNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHY 1026
+ C PCL+ +C GY C C P +TG C+ + D C+S PC + G C++ +
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF 789
Query: 1027 TCDCKSGFFGTHCETNAN-DCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCT 1084
+C C GF G CE C +PC + C + C C T C+ ++ C
Sbjct: 790 SCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCA 849
Query: 1085 SIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELN-----SVICLNGGICVD 1139
PC C ++ F C+C +G+TG C + +C + L+ S +C NGG+CVD
Sbjct: 850 QKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVD 909
Query: 1140 GPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENE 1199
G ++ C C PGF G C+ ++N C S PC +GA C +GY+C+C PG+ G +C E
Sbjct: 910 S-GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKE 968
Query: 1200 LE-CIPNSC-VHELCMENEPGSTCLCTPGFMTCSIGLLCGDEI 1240
L+ C C H C G C C PGF +GL C ++
Sbjct: 969 LDACQSQPCHNHGTCTPKPGGFHCACPPGF----VGLRCEGDV 1007
Score = 225 bits (573), Expect = 6e-58
Identities = 142/483 (29%), Positives = 196/483 (40%), Gaps = 93/483 (19%)
Query: 852 LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE----- 906
LC PC N TCL+L C C F G+ C+ CQ+ G C+
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPA 86
Query: 907 ---------DMVNNFRCICRPGFSGSLCEIEINE-------------------------- 931
+ +F C C PGF+G C+ ++ +
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 932 -------------CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKC--KISPCL 976
CS+ PC N G C+ + C+C P + G CE DVN+C PC
Sbjct: 147 PGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCP 206
Query: 977 DEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVC----IDGINHYTCDCKS 1032
+C + CLC G G CE+ C C + G C + C C
Sbjct: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 1033 GFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDC-TSIP--C 1088
GF G CE N ++C+S+ C + G C + ++ Y C C T C +++C T P C
Sbjct: 267 GFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHC 326
Query: 1089 MNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCR 1148
N G CQ SA F C+C G+ G CE+++D+C + C G C+D G +F C
Sbjct: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI-----AATCAPGSTCIDRVG-SFSCL 380
Query: 1149 CLPGFSGQFCEININECSSSPCLHGADCEDH--INGYVCKCQPGWSGHHCENEL-ECI-- 1203
C PG +G C + + C S PC A C + +C CQPG+SG C +L EC+
Sbjct: 381 CPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439
Query: 1204 ---PNSCVHELCMENEPGS-TCLCTPGF--------------MTCSIGLLCGDEIRRITC 1245
P+ C H N PGS CLC PG+ C G C D + C
Sbjct: 440 QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499
Query: 1246 LTP 1248
L P
Sbjct: 500 LCP 502
Score = 70.5 bits (171), Expect = 3e-11
Identities = 30/74 (40%), Positives = 42/74 (56%), Gaps = 5/74 (6%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
C NGG C++SG S +C+C G++GS C + V+ C+ C GATC++ P GY C
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE-----SRPCQNGATCMAQPSGYLCQ 955
Query: 2679 CPLGTTGIYCEQAL 2692
C G G C + L
Sbjct: 956 CAPGYDGQNCSKEL 969
Score = 65.9 bits (159), Expect = 6e-10
Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
C NGGTC S S +C C +GW G+ C E + C C+ G+TCI ++C
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA-----TCAPGSTCIDRVGSFSCL 380
Query: 2679 CPLGTTGIYCE-QALSISDP 2697
CP G TG+ C + + +S P
Sbjct: 381 CPPGRTGLLCHLEDMCLSQP 400
Score = 65.5 bits (158), Expect = 8e-10
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P S+ Q H +PC C NG TC+ + C C G+ G C++ + C +
Sbjct: 920 PGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ---- 975
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C TC P G+ C CP G G+ CE
Sbjct: 976 -PCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
Score = 63.9 bits (154), Expect = 2e-09
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 4/115 (3%)
Query: 2589 HFRGLGNPEGHPNAGRSVGQCHASP-CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTE 2647
H + G P+ G + QC CS C NGG C+ + + C+C G++G C
Sbjct: 134 HIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER 193
Query: 2648 TVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSN 2702
V+ C + P C +G +C + + C CP+G G CE P SN
Sbjct: 194 DVNECFQDPGP---CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSN 245
Score = 63.9 bits (154), Expect = 2e-09
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
+ +C +SPC+ NGG C + + +C C G++G C V C DP C G
Sbjct: 552 IDECRSSPCA-----NGGQCQDQPGAFHCKCLPGFEGPRCQTEVDEC--LSDP---CPVG 601
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQAL 2692
A+C+ LP + C CP G TG CE L
Sbjct: 602 ASCLDLPGAFFCLCPSGFTGQLCEVPL 628
Score = 63.9 bits (154), Expect = 2e-09
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 12/102 (11%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P +G C ++PC+ +GGTC + C C TG+ G C+E ++ C H P
Sbjct: 686 PECEAELGGCISAPCA-----HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC---HSGP 737
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS--ISDPSF 2699
C G +C P GY C CP TG C+ + +S P F
Sbjct: 738 --CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCF 777
Score = 63.5 bits (153), Expect = 3e-09
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 9/116 (7%)
Query: 2579 TLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASP--CSLMKCGNGGTCIESGTSVYCNC 2636
T Q+ EKD F P G C +P C +C NGGTC + + C C
Sbjct: 248 TCQLMPEKDSTFHLCLCPPGFIGP-----DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
Query: 2637 TTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQAL 2692
W G C+E V C+ + P HC G TC + + C C G G CE+ L
Sbjct: 303 PETWTGWDCSEDVDECETQGPP--HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
Score = 62.0 bits (149), Expect = 9e-09
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Query: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPY 2400
LC N G C+ + FC CP + G LCQ CE+ PC NGATC+ + + +C C
Sbjct: 900 LCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP-SGYLCQCAP 958
Query: 2401 GRSGPLCTDAINITQ 2415
G G C+ ++ Q
Sbjct: 959 GYDGQNCSKELDACQ 973
Score = 58.2 bits (139), Expect = 1e-07
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
C C + GTC C CP Y+G C + +C + PC NG +C P G C
Sbjct: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG-GYYC 753
Query: 2397 LCPYGRSGPLCTDAIN--ITQPRFSG 2420
CP +GP C + + ++ P F+G
Sbjct: 754 TCPPSHTGPQCQTSTDYCVSAPCFNG 779
Score = 58.2 bits (139), Expect = 1e-07
Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
C C N G+C +C CP ++G CQ ++ C + PC NG TCV + GT C
Sbjct: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT-FSC 791
Query: 2397 LCPYGRSGPLC 2407
LC G GP C
Sbjct: 792 LCAMGFQGPRC 802
Score = 57.4 bits (137), Expect = 2e-07
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 2335 HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGT 2392
HV C C+N TC++ C+C Y G+ C + +C++ PC N TC PK G
Sbjct: 930 HVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPG- 988
Query: 2393 DIVCLCPYGRSGPLC 2407
C CP G G C
Sbjct: 989 GFHCACPPGFVGLRC 1003
Score = 56.2 bits (134), Expect = 5e-07
Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
CRNGG C + +F C C+ W G +C +++ C+ C S CI D+ S+SCLC G
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPG 384
Query: 2943 WVGRYC 2948
G C
Sbjct: 385 RTGLLC 390
Score = 55.8 bits (133), Expect = 6e-07
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 2877 TACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSY 2935
TAC C NGG C + + C C P G C S C++ C + C+ ++ ++
Sbjct: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCV-NRPGTF 789
Query: 2936 SCLCTLGWVGRYCENKTSFSTA 2957
SCLC +G+ G CE K S A
Sbjct: 790 SCLCAMGFQGPRCEGKLRPSCA 811
Score = 55.5 bits (132), Expect = 8e-07
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2337 PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDI 2394
P CA CRN TC + C CP Y+G CQ C PC + C+ ++G
Sbjct: 808 PSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCL-QTGPSF 866
Query: 2395 VCLCPYGRSGPLC 2407
CLC G +GPLC
Sbjct: 867 HCLCLQGWTGPLC 879
Score = 55.1 bits (131), Expect = 1e-06
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C + C NGG+C F C+CLP + G C V CL++ C + C+ D ++ C
Sbjct: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFC 613
Query: 2938 LCTLGWVGRYCE 2949
LC G+ G+ CE
Sbjct: 614 LCPSGFTGQLCE 625
Score = 55.1 bits (131), Expect = 1e-06
Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 7/94 (7%)
Query: 2603 GRSVGQCHA--SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH---- 2656
G + G C C+ C C+++G S +C C GW G C +S+C
Sbjct: 835 GYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 2657 -DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
D C G C+ Y C CP G G C+
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQ 928
Score = 53.5 bits (127), Expect = 3e-06
Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 3/90 (3%)
Query: 2603 GRSVGQCHASP-CSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
GR+ CH C C C + S C C G+ G C + + C P
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP 443
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G +C++ P + C CP G TG CE
Sbjct: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
Score = 53.1 bits (126), Expect = 4e-06
Identities = 35/114 (30%), Positives = 45/114 (39%), Gaps = 13/114 (11%)
Query: 2608 QCHASPCSLMKCGNGGTC----IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
+ A PC C NGGTC + T C C G+ G C +P++ H C
Sbjct: 232 ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC-----EVNPDNCVSHQCQ 286
Query: 2664 RGATCISLPHGYTCFCPLGTTGIYCEQALSISD----PSFRSNELSWMSFASFH 2713
G TC YTC CP TG C + + + P R+ S SFH
Sbjct: 287 NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
Score = 53.1 bits (126), Expect = 4e-06
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATC 2386
++++ C H CRN GTC + + C C + G C+ C C G+TC
Sbjct: 313 EDVDECETQGPPH--CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
Query: 2387 VPKSGTDIVCLCPYGRSGPLC 2407
+ + G+ CLCP GR+G LC
Sbjct: 371 IDRVGS-FSCLCPPGRTGLLC 390
Score = 52.8 bits (125), Expect = 5e-06
Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 8/90 (8%)
Query: 2608 QCHASP--CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS-TCDPEHDPPHHCSR 2664
QC S C C NGGTC+ + C C G++G C + +C D P C
Sbjct: 763 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA---DSP--CRN 817
Query: 2665 GATCISLPHGYTCFCPLGTTGIYCEQALSI 2694
ATC P G C CP G TG C+ + +
Sbjct: 818 RATCQDSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 51.6 bits (122), Expect = 1e-05
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P + + +C + C +GG+C+ + S C C G+ GS C + C +
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQ---- 482
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G+TC+ L + C CP G G CE
Sbjct: 483 -PCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Score = 51.2 bits (121), Expect = 2e-05
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 2332 ENCHV-PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASC--ENNPCGNGATC 2386
E C + +C+ + C N G C++ + C CP + G C+ C + PC G +C
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
Query: 2387 VPKSGTDIVCLCPYGRSGPLC 2407
G+ CLCP G+ GP C
Sbjct: 212 HNTLGS-FQCLCPVGQEGPRC 231
Score = 51.2 bits (121), Expect = 2e-05
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
N + + C + PC N GTC +C C G+ G C V C D P
Sbjct: 964 NCSKELDACQSQPC-----HNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC---LDQPC 1015
Query: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
H + A C SL + + C C G TG +CE
Sbjct: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
Score = 50.8 bits (120), Expect = 2e-05
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATC 2386
++++ C + C + G+C++ + C CP Y+G C+ C + PC G+TC
Sbjct: 431 QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTC 490
Query: 2387 VPKSGTDIVCLCPYGRSGPLC 2407
+ T CLCP G G LC
Sbjct: 491 LDLLAT-FHCLCPPGLEGQLC 510
Score = 50.4 bits (119), Expect = 3e-05
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 13/91 (14%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCE----------NNPCGNGATC 2386
CA C N C+ + C C + ++G LC +SC+ ++ C NG C
Sbjct: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC 907
Query: 2387 VPKSGTDIVCLCPYGRSGPLCTDAINITQPR 2417
V SG C CP G G LC D +N + R
Sbjct: 908 VD-SGPSYFCHCPPGFQGSLCQDHVNPCESR 937
Score = 50.1 bits (118), Expect = 4e-05
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
++ +C G + C +GG C +F+C C P + G+ C + CL+ C S C+
Sbjct: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCL 491
Query: 2929 PDQSFSYSCLCTLGWVGRYCENKTS 2953
D ++ CLC G G+ CE +T+
Sbjct: 492 -DLLATFHCLCPPGLEGQLCEVETN 515
Score = 49.7 bits (117), Expect = 5e-05
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
C C N G C C+C + G CQ C ++PC GA+C+ G C
Sbjct: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA-FFC 613
Query: 2397 LCPYGRSGPLC---TDAINITQPR 2417
LCP G +G LC A N+ QP+
Sbjct: 614 LCPSGFTGQLCEVPLCAPNLCQPK 637
Score = 49.3 bits (116), Expect = 6e-05
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 12/83 (14%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC-----------LNNLCLHQSLC 2927
C C C G +F C CL W G CN +S +++LC + LC
Sbjct: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC 907
Query: 2928 IPDQSFSYSCLCTLGWVGRYCEN 2950
+ D SY C C G+ G C++
Sbjct: 908 V-DSGPSYFCHCPPGFQGSLCQD 929
Score = 49.3 bits (116), Expect = 6e-05
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C C+NG C + + C+C P + G C++ + +C + C + C P + C
Sbjct: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPG-GFHC 992
Query: 2938 LCTLGWVGRYCE 2949
C G+VG CE
Sbjct: 993 ACPPGFVGLRCE 1004
Score = 48.9 bits (115), Expect = 8e-05
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 2338 WCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ---FASCENNPCGNGATCVPKSGTDI 2394
+C C N GTC++ C C + G C+ SC ++PC N ATC S
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC-QDSPQGP 828
Query: 2395 VCLCPYGRSGPLCTDAINI 2413
CLCP G +G C +++
Sbjct: 829 RCLCPTGYTGGSCQTLMDL 847
Score = 48.5 bits (114), Expect = 1e-04
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
C NGG C +G ++ C C P + G+ C V+ C + C + + C+ S Y C C G
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS-GYLCQCAPG 959
Query: 2943 WVGRYCENK 2951
+ G+ C +
Sbjct: 960 YDGQNCSKE 968
Score = 48.1 bits (113), Expect = 1e-04
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 2634 CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
C C GW G C + C C+ G TC P GY C CP G TG C + ++
Sbjct: 677 CVCDVGWTGPECEAELGGCISA-----PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMT 731
Score = 47.8 bits (112), Expect = 2e-04
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Query: 2339 CAHHLCRNNGT--CISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDI 2394
C C GT C S +C+C ++G+ C+ C + PC +G TC +G+ +
Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069
Query: 2395 --VCLCPYGRSGPLCT 2408
+C CP G GP C+
Sbjct: 1070 GFICHCPKGFEGPTCS 1085
Score = 47.4 bits (111), Expect = 2e-04
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL----CLHQSLCIPDQSFS 2934
C + C+NGG C T++C C W G C++ V C + C + + S
Sbjct: 280 CVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTC-QNSAGS 338
Query: 2935 YSCLCTLGWVGRYCE 2949
+ C+C GW G CE
Sbjct: 339 FHCVCVSGWGGTSCE 353
Score = 47.0 bits (110), Expect = 3e-04
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 6/79 (7%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENN---PCGNGATCVPKSGTD 2393
C H C+N GTC + C CP ++G C CE C NG TC +G+
Sbjct: 280 CVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS- 338
Query: 2394 IVCLCPYGRSGPLCTDAIN 2412
C+C G G C + ++
Sbjct: 339 FHCVCVSGWGGTSCEENLD 357
Score = 46.2 bits (108), Expect = 5e-04
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 7/90 (7%)
Query: 2603 GRSVGQCHA--SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
G + +C A + C C G TC++ + +C C G +G C + C
Sbjct: 466 GYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC-----ASA 520
Query: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690
C A C L +G+ C C G +G CE+
Sbjct: 521 PCLNHADCHDLLNGFQCICLPGFSGTRCEE 550
Score = 46.2 bits (108), Expect = 5e-04
Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 4/103 (3%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV--SCLNNLCLHQSLCIPDQSFSYS 2936
C C NGG C TFSC C + G C + SC ++ C +++ C D
Sbjct: 771 CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC-QDSPQGPR 829
Query: 2937 CLCTLGWVGRYCENKTSFSTAK-FMGNSYIKYIDPNYRMRNLQ 2978
CLC G+ G C+ K NS+ P++ LQ
Sbjct: 830 CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Score = 45.8 bits (107), Expect = 7e-04
Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 33/107 (30%)
Query: 2334 CHVPWCAHHLCRNNGTCISDNENLFCECPR----------------------------LY 2365
C VP CA +LC+ C + C CP +
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGW 683
Query: 2366 SGKLC--QFASCENNPCGNGATCVPK-SGTDIVCLCPYGRSGPLCTD 2409
+G C + C + PC +G TC P+ SG + C CP G +GP C++
Sbjct: 684 TGPECEAELGGCISAPCAHGGTCYPQPSGYN--CTCPTGYTGPTCSE 728
Score = 45.8 bits (107), Expect = 7e-04
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C+ C N TC +S C C TG+ G C + C + C R + C+
Sbjct: 810 CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQK-----PCPRNSHCLQTGP 864
Query: 2674 GYTCFCPLGTTGIYCEQALS 2693
+ C C G TG C LS
Sbjct: 865 SFHCLCLQGWTGPLCNLPLS 884
Score = 45.1 bits (105), Expect = 0.001
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 9/82 (10%)
Query: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCV 2387
+N+++C CA TCI + C CP +G LC C + PC A C
Sbjct: 354 ENLDDCIAATCAP-----GSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCS 408
Query: 2388 --PKSGTDIVCLCPYGRSGPLC 2407
P +G+ + CLC G SGP C
Sbjct: 409 TNPLTGSTL-CLCQPGYSGPTC 429
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/79 (30%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS--------CLNNLCLHQSLCIPD 2930
C N C NGG C C C P + G+ C + V+ C H +L
Sbjct: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL---- 215
Query: 2931 QSFSYSCLCTLGWVGRYCE 2949
S+ CLC +G G CE
Sbjct: 216 --GSFQCLCPVGQEGPRCE 232
Score = 44.3 bits (103), Expect = 0.002
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 9/79 (11%)
Query: 2879 CGYNTCRNGGECTVNGTTFS--CRCLPDWAGNTCNQSV-SCL-----NNLCLHQSLCIPD 2930
C C +C+ N T S C C P ++G TC+Q + CL + C H C+ +
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCL-N 454
Query: 2931 QSFSYSCLCTLGWVGRYCE 2949
S++CLC G+ G CE
Sbjct: 455 TPGSFNCLCPPGYTGSRCE 473
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
C +GG C + ++C C + G TC++ + +C + CL+ C P Y C C
Sbjct: 700 CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG-GYYCTCPPS 758
Query: 2943 WVGRYCENKTSF 2954
G C+ T +
Sbjct: 759 HTGPQCQTSTDY 770
Score = 43.9 bits (102), Expect = 0.003
Identities = 27/86 (31%), Positives = 33/86 (38%), Gaps = 11/86 (12%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C PC C + YC C G G +C + DP H P C G
Sbjct: 1007 VDECLDQPCHPT---GTAACHSLANAFYCQCLPGHTGQWCEVEI---DPCHSQP--CFHG 1058
Query: 2666 ATCISL---PHGYTCFCPLGTTGIYC 2688
TC + P G+ C CP G G C
Sbjct: 1059 GTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 43.1 bits (100), Expect = 0.004
Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C C N +C F C CLP ++G C + + C ++ C + C DQ ++ C
Sbjct: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQC-QDQPGAFHC 575
Query: 2938 LCTLGWVGRYCENK 2951
C G+ G C+ +
Sbjct: 576 KCLPGFEGPRCQTE 589
Score = 42.0 bits (97), Expect = 0.010
Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTF-SCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
C + C G C + + C C+P W G C C N C++ +C+ C
Sbjct: 122 CPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYP-QIQC 180
Query: 2938 LCTLGWVGRYCE 2949
C G+ G CE
Sbjct: 181 HCPPGFEGHACE 192
Score = 42.0 bits (97), Expect = 0.010
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 2874 CDGT---ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIP 2929
C+G +C + CRN C + C C + G +C + C C S C+
Sbjct: 802 CEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCL- 860
Query: 2930 DQSFSYSCLCTLGWVGRYC 2948
S+ CLC GW G C
Sbjct: 861 QTGPSFHCLCLQGWTGPLC 879
Score = 41.6 bits (96), Expect = 0.013
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 9/81 (11%)
Query: 2339 CAHHLCRNNGTC--ISDNENLF--CECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGT 2392
C C N GTC + + ++ F C CP + G C+ +C ++ C NG TC + G
Sbjct: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTC--QDGL 295
Query: 2393 D-IVCLCPYGRSGPLCTDAIN 2412
D CLCP +G C++ ++
Sbjct: 296 DTYTCLCPETWTGWDCSEDVD 316
Score = 41.2 bits (95), Expect = 0.016
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 8/81 (9%)
Query: 2876 GTACGYN-------TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCI 2928
GT+C N TC G C +FSC C P G C+ CL+ C + C
Sbjct: 349 GTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCS 408
Query: 2929 PDQ-SFSYSCLCTLGWVGRYC 2948
+ + S CLC G+ G C
Sbjct: 409 TNPLTGSTLCLCQPGYSGPTC 429
Score = 40.0 bits (92), Expect = 0.036
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCV---PKSGTDIVCLC 2398
C +C + + C CP G C+ + C C NG TC K T +CLC
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 2399 PYGRSGPLC 2407
P G GP C
Sbjct: 265 PPGFIGPDC 273
Score = 39.3 bits (90), Expect = 0.062
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
C C TC+ C CP G+LC+ + C + PC N A C C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLL-NGFQC 537
Query: 2397 LCPYGRSGPLCTDAIN 2412
+C G SG C + I+
Sbjct: 538 ICLPGFSGTRCEEDID 553
Score = 38.9 bits (89), Expect = 0.081
Identities = 33/127 (25%), Positives = 49/127 (38%), Gaps = 31/127 (24%)
Query: 2589 HFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTET 2648
H + L EG P V +C + PC + G +C++ + +C C +G+ G C
Sbjct: 574 HCKCLPGFEG-PRCQTEVDECLSDPCPV-----GASCLDLPGAFFCLCPSGFTGQLCE-- 625
Query: 2649 VSTCDPEHDPPHH------------CSRGATCISLP-------HGY----TCFCPLGTTG 2685
V C P P C G+ + P HG+ +C C +G TG
Sbjct: 626 VPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTG 685
Query: 2686 IYCEQAL 2692
CE L
Sbjct: 686 PECEAEL 692
Score = 38.9 bits (89), Expect = 0.081
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLC 2398
C C +C+ FC CP ++G+LC+ C N C C + CLC
Sbjct: 593 CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQK-DKANCLC 651
Query: 2399 PYGRSG 2404
P G G
Sbjct: 652 PDGSPG 657
Score = 38.1 bits (87), Expect = 0.14
Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 17/93 (18%)
Query: 2876 GTACGY--NTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVSCLN-NLCLHQSLC---- 2927
G CG C NGG C +++ +C+C P + G TC C N LC + C
Sbjct: 25 GLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALL 84
Query: 2928 -----IPDQ----SFSYSCLCTLGWVGRYCENK 2951
+P + S+ C C G+ G C+ K
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAK 117
Score = 37.7 bits (86), Expect = 0.18
Identities = 68/335 (20%), Positives = 106/335 (31%), Gaps = 66/335 (19%)
Query: 2091 TSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFF--P 2148
+S + + + +CHNGG C + SG S+ C CP F G C+ P
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLC----VDSG-PSYFCHCPPGFQGSLCQDHVNPCESRP 938
Query: 2149 SFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEG 2208
NG + + P + L +G NC K+ L +
Sbjct: 939 CQNGATCMAQP---------------------SGYLCQCAPGYDGQNCSKE---LDACQS 974
Query: 2209 RPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQK 2268
+P +G T P P G G+ C ++ P
Sbjct: 975 QPCHNHG-----------------TCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
Query: 2269 KDTEISHA-SQAYFESMFLGHIPANVQIHKKAGPVYG---FRGCILDLQVNNKEFFIIDE 2324
T H+ + A++ GH ++ + P + F G + + FI
Sbjct: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEV--EIDPCHSQPCFHGGTCEATAGSPLGFICHC 1075
Query: 2325 ARHGKNIENCH-VPWCAHHLCRNNGTCISDNENLF---CECPRLYSGKLCQFASCEN--- 2377
+ + H P C H C + G C+ + F C C Y G C
Sbjct: 1076 PKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCG 1135
Query: 2378 --NPCGNGATCVPKSGTD---IVCLCPYGRSGPLC 2407
+PC +C +G C CP+ GP C
Sbjct: 1136 PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRC 1170
Score = 36.2 bits (82), Expect = 0.53
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 10/89 (11%)
Query: 2610 HASP-CSLMKCGNGGTCIES---GTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
H +P C C +GG C+ S G C C +G+ G C PP C
Sbjct: 1086 HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCL--TPPAPKGCGPPSPCLYN 1143
Query: 2666 ATCISLPH----GYTCFCPLGTTGIYCEQ 2690
+C G+ C CP + G C++
Sbjct: 1144 GSCSETTGLGGPGFRCSCPHSSPGPRCQK 1172
Score = 35.8 bits (81), Expect = 0.69
Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 5/45 (11%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFF 2147
C + C NGG C A + QC CP F G CE+D F
Sbjct: 160 CSANPCVNGGVCLATY-----PQIQCHCPPGFEGHACERDVNECF 199
Score = 35.0 bits (79), Expect = 1.2
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
Query: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
P C C NGGTC G+ ++ C CP +TG C +D
Sbjct: 277 PDNCVSHQCQNGGTC-----QDGLDTYTCLCPETWTGWDCSED 314
Score = 34.7 bits (78), Expect = 1.5
Identities = 22/85 (25%), Positives = 30/85 (35%), Gaps = 7/85 (8%)
Query: 2874 CDGTA--CGYNTCRNGGE--CTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLC- 2927
C+G C C G C F C+CLP G C + C + C H C
Sbjct: 1003 CEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 2928 -IPDQSFSYSCLCTLGWVGRYCENK 2951
+ C C G+ G C ++
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 33.5 bits (75), Expect = 3.4
Identities = 37/126 (29%), Positives = 46/126 (36%), Gaps = 37/126 (29%)
Query: 2619 CGNGGTCIE----SGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC------ 2668
C NGGTC+ GT C C G+ G ET DP + C G +C
Sbjct: 35 CANGGTCLSLSLGQGT---CQCAPGFLG----ETCQFPDPCQN-AQLCQNGGSCQALLPA 86
Query: 2669 -ISLPH-------GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHI 2720
+ LP + C C G TG C+ L P SF S R + HI
Sbjct: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP---------SFCS--KRGRCHI 135
Query: 2721 QLQFQP 2726
Q +P
Sbjct: 136 QASGRP 141
Score = 33.1 bits (74), Expect = 4.4
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 7/61 (11%)
Query: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE--KDAGLFFPSFNGNSYLEL 2158
+ C C NGG+C+ S G + C CP TG C+ D + P FNG + +
Sbjct: 731 TACHSGPCLNGGSCNP---SPG--GYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785
Query: 2159 P 2159
P
Sbjct: 786 P 786
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 405 bits (1040), Expect = e-112
Identities = 209/646 (32%), Positives = 292/646 (45%), Gaps = 113/646 (17%)
Query: 645 EDCKSASCKNGTTSTH--------------LRGYFFRKCVP------------------- 671
++CK A CK G H +G F +CVP
Sbjct: 238 KECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCET 297
Query: 672 GFKGTQCEIDIDECAS-HPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRC 730
+ G C+ D++ C S HPC NG TCI+ D + C C GY G C
Sbjct: 298 NWGGLLCDKDLNYCGSHHPCTNGGTCINAE-------------PDQYRCTCPDGYSGRNC 344
Query: 731 EQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLY 790
E+ C N C + +C ++ ++C C S W G C + +EC NPC TC D
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQV 404
Query: 791 KSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRY 850
+ C C W G C + NEC+ PC+N C + G + C C P + G CH
Sbjct: 405 DGFECICPEQWVGATCQLDANECEGKPCLNAFSC--KNLIGGYYCDCIPGWKGINCHINV 462
Query: 851 NLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVN 910
N C C++ TC LV+ Q C+C F G++CE++ +C C G CED+ +
Sbjct: 463 NDC---RGQCQHGGTCKDLVNGYQ-CVCPRGFGGRHCELERDECASSPCHSGGLCEDLAD 518
Query: 911 NFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKC 970
F C C GFSG LCE++++ C PC+N C +L ++C C ++ G C + C
Sbjct: 519 GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPC 578
Query: 971 KISPCL-----------------------DEENCVYRTDG-YNCLCAPGYTGINCEINLD 1006
C CV + G ++C+C G+TG C N+D
Sbjct: 579 PGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID 638
Query: 1007 ECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPC-LHGRCTELINEYPC 1065
+CL +PC + G CID ++ + C C SG+ G C+TN NDCL +PC GRC +L+N++ C
Sbjct: 639 DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 698
Query: 1066 SCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEP- 1124
+CD C + C + C N G C S F C CP G+ G+ C + ++ P
Sbjct: 699 ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 758
Query: 1125 ---------------------------------ELNSVICLNGGICVDGPGHTFDCRCLP 1151
+ N + C NGGICVDG + F C C P
Sbjct: 759 PCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGV-NWFRCECAP 817
Query: 1152 GFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE 1197
GF+G C INI+EC SSPC +GA C D INGY C C PG +G C+
Sbjct: 818 GFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 863
Score = 372 bits (955), Expect = e-102
Identities = 221/776 (28%), Positives = 319/776 (41%), Gaps = 108/776 (13%)
Query: 521 NSSC---WFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQH 577
N +C W E + +C GC+ L + C W G +EC
Sbjct: 228 NKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC---------DECVP 278
Query: 578 EAVCKDE--INRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALS---HNCNCSGL 632
C + +C+C ++ G LC +++YC +H + G C+ + C C
Sbjct: 279 YPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCP-- 336
Query: 633 QRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKN 692
Y CE C S C NG + + F C G+ G C +DIDECAS+PC
Sbjct: 337 DGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAA 396
Query: 693 GATCIDQPGNYFCQCVPPF------------------------KVVDGFSCLCNPGYVGI 728
G TC+DQ + C C + ++ G+ C C PG+ GI
Sbjct: 397 GGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGI 456
Query: 729 RCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTD 788
C +++DC C+H TCKDL YQCVC + G CE E +EC +PC + C D
Sbjct: 457 NCHINVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCED 515
Query: 789 LYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQ 848
L + C C G++G C +++ C+ PC NG C+ + G + C CP + G+ C
Sbjct: 516 LADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYN--LEGDYYCACPDDFGGKNCSV 573
Query: 849 RYNLCD---------------------LLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
C C + C++ N CIC F G C
Sbjct: 574 PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC 633
Query: 888 EIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLT 947
++ DCL C++ G C D V+ FRC C G+ G LC+ N+C +PC + G C DL
Sbjct: 634 HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLV 693
Query: 948 NRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEI-NLD 1006
N F+C C+ + G C +C C + C D + C C PG+ G C +
Sbjct: 694 NDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS 753
Query: 1007 ECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELINEYPC 1065
CL PC++ G C+ ++C C+ G+ G C N NDC PC +G C + +N + C
Sbjct: 754 SCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRC 813
Query: 1066 SCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPE 1125
C C+I I++C S PC C +G+ C CP G G C++ I
Sbjct: 814 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI------- 866
Query: 1126 LNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHG-ADCEDHINGYV 1184
G G + R P G + +C+S CL G DC
Sbjct: 867 --------------GFGRSCWSRGTPFPHGSSW---VEDCNSCRCLDGRRDCS------- 902
Query: 1185 CKCQPGWSGHHCENELECIPNSC-VHELCMENEPGSTCLCTPGFMTCSIGLLCGDE 1239
K GW + E + C + + C+E PG CL P C CG E
Sbjct: 903 -KVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQ-CLRPP----CEAWGECGAE 952
Score = 317 bits (812), Expect = 1e-85
Identities = 196/654 (29%), Positives = 280/654 (42%), Gaps = 90/654 (13%)
Query: 388 CEKDYPCSCISGFTEKNCEKAI--DHCKLLSINCLNEEWC---FNIIGRFKYVCIP--GC 440
C++ +C+ G+ K C++A+ C LL C C + GRF C+P GC
Sbjct: 223 CDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGC 282
Query: 441 TKNPC---WFLK-----NVYLIHQHLCYCG----VTFHGICQDKGPAQFEYVWQLGFAGS 488
C W L + L YCG T G C + P Q+ G++G
Sbjct: 283 VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGR 342
Query: 489 EGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSC---WFPHEGTKEI-------CANG 538
EK + + + C + P C W +I CA G
Sbjct: 343 NCEKAE-----HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAG 397
Query: 539 CSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIG 598
+C+ + D + +C +W G + + + C + CK+ I C C + G
Sbjct: 398 GTCVDQVDG--FECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKG 455
Query: 599 RLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTS 658
C +NV+ C G G C L + C + + CE++ ++C S+ C +G
Sbjct: 456 INCHINVNDCRGQCQHG--GTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLC 513
Query: 659 THLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPF------- 711
L F C GF G CE+D+D C PC+NGA C + G+Y+C C F
Sbjct: 514 EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV 573
Query: 712 ----------KVVDG-------------------------------FSCLCNPGYVGIRC 730
+V+DG FSC+C+ G+ G C
Sbjct: 574 PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC 633
Query: 731 EQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLY 790
++IDDC+ C + TC D +++C C S WEG C+ N+C +PC + C DL
Sbjct: 634 HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLV 693
Query: 791 KSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRY 850
+ C C GW G+ C +CD+ C NGG C++S F C CPP + G C
Sbjct: 694 NDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS--GDTFRCACPPGWKGSTCAVAK 751
Query: 851 NLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVN 910
N L NPC N TC+ A+ CICR+ +EG+ C + DC L C + G C D VN
Sbjct: 752 N-SSCLPNPCVNGGTCVG-SGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVN 809
Query: 911 NFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE 964
FRC C PGF+G C I I+EC S PC TCVD N + C+C P GP C+
Sbjct: 810 WFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 863
Score = 313 bits (801), Expect = 2e-84
Identities = 179/565 (31%), Positives = 252/565 (44%), Gaps = 61/565 (10%)
Query: 726 VGIRCEQDIDDCILNA-CEHNSTCKDLHLSYQC------VCLSDWEGNFCEQESNECKMN 778
+ +RC+++ N C + D Y C C+ W G C++ CK
Sbjct: 194 IRVRCDENYYSATCNKFCRPRN---DFFGHYTCDQYGNKACMDGWMGKECKEAV--CKQG 248
Query: 779 PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCP 838
+ CT C C+ GW G+ C +EC P G C E P Q C C
Sbjct: 249 CNLLHGGCT---VPGECRCSYGWQGRFC----DECVPYPGCVHGSCVE---PWQ--CNCE 296
Query: 839 PLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLS 898
+ G C + N C H+PC N TC+ C C + + G+NCE C
Sbjct: 297 TNWGGLLCDKDLNYCGS-HHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNP 355
Query: 899 CQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEY 958
C + G C ++ + F C C G+SG C ++I+EC+S PC GTCVD + F C C ++
Sbjct: 356 CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQW 415
Query: 959 HGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGV 1018
G C+LD N+C+ PCL+ +C GY C C PG+ GINC IN+++C + C H G
Sbjct: 416 VGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ-CQHGGT 474
Query: 1019 CIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCK 1077
C D +N Y C C GF G HCE ++C S+PC G C +L + + C C + C+
Sbjct: 475 CKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 534
Query: 1078 IKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCE-----------KSIDNC---AE 1123
+ ++ C PC N C + C CP + G C + ID C A
Sbjct: 535 VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAG 594
Query: 1124 PELN----SVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDH 1179
P + S +C G CV PG F C C GF+G +C NI++C PC +G C D
Sbjct: 595 PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDE 654
Query: 1180 INGYVCKCQPGWSGHHCE-NELECIPNSC-VHELCMENEPGSTCLCTPGF---------- 1227
++ + C C GW G C+ N +C+P+ C C + C C G+
Sbjct: 655 VDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREF 714
Query: 1228 ----MTCSIGLLCGDEIRRITCLTP 1248
TCS G C D C P
Sbjct: 715 QCDAYTCSNGGTCYDSGDTFRCACP 739
Score = 230 bits (586), Expect = 2e-59
Identities = 188/774 (24%), Positives = 289/774 (37%), Gaps = 103/774 (13%)
Query: 174 CQESLSSEFCSG-HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKR 232
C+E++ + C+ HG C C C + G++C E C P +GSC+
Sbjct: 240 CKEAVCKQGCNLLHGGCTVPG-----ECRCSYGWQGRFCDE---CVPYPGCVHGSCV--- 288
Query: 233 ENWDEQAYECVCHPPFTGKNCSEIIGQC-QPHVCFHGN-CSNITSNSFICECDEQFSGPF 290
+ ++C C + G C + + C H C +G C N + + C C + +SG
Sbjct: 289 -----EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRN 343
Query: 291 CEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKI 350
CE + C S G C S + CP G S D+ E + PC G C+
Sbjct: 344 CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQ 403
Query: 351 SNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAID 410
+ CIC + C+ CE P N +CK Y C CI G+ NC ++
Sbjct: 404 VDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVN 463
Query: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQ 470
C+ C + C +++ ++ VC G C ++ C+ G G+C+
Sbjct: 464 DCR---GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDE--CASSPCHSG----GLCE 514
Query: 471 DKGPAQFEYVWQLGFAG---------------SEGEKCQGVIDAYF------FLAANCT- 508
D F GF+G G +C + Y+ F NC+
Sbjct: 515 DLADG-FHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV 573
Query: 509 ------EDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNM 562
A V D +++ P +C C+S+ + +C + G
Sbjct: 574 PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGG-NFSCICDSGFTGTY 632
Query: 563 YLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLA 622
EN D C++ C DE++ RC C + G LC N + CL + S G C
Sbjct: 633 CHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHS-RGRCYD 691
Query: 623 LSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEI-D 681
L ++ C+ ++ C C + +C NG T F C PG+KG+ C +
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 682 IDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNA 741
C +PC NG TC+ + FSC+C G+ G C + +DC
Sbjct: 752 NSSCLPNPCVNGGTCVGSGAS--------------FSCICRDGWEGRTCTHNTNDCNPLP 797
Query: 742 CEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGW 801
C + C D ++C C + G C +EC+ +PC +TC D YRC C G
Sbjct: 798 CYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGR 857
Query: 802 TGQNCSEEI--------------------NECDSDPCMNGGL-CHE-------STIPGQF 833
G C E I +C+S C++G C + + GQ
Sbjct: 858 AGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQP 917
Query: 834 VCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
L GQ C ++ L PC C A + C+ R NC
Sbjct: 918 EALSAQCPLGQRCLEKAP-GQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 970
Score = 73.2 bits (178), Expect = 4e-12
Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC--NQSVSCLNNLCLHQSLCIPDQSFSYS 2936
C TC NGG C +G TF C C P W G+TC ++ SCL N C++ C+ S+S
Sbjct: 716 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV-GSGASFS 774
Query: 2937 CLCTLGWVGRYCENKTS 2953
C+C GW GR C + T+
Sbjct: 775 CICRDGWEGRTCTHNTN 791
Score = 63.2 bits (152), Expect = 4e-09
Identities = 42/116 (36%), Positives = 48/116 (41%), Gaps = 11/116 (9%)
Query: 2306 RGCILDLQVNNKEFFIIDEARHGKNIENCHVP--WCAHHLCRNNGTCISDNENLFCECPR 2363
RG DL N + D+ GK CH C + C N GTC + C CP
Sbjct: 686 RGRCYDLV--NDFYCACDDGWKGKT---CHSREFQCDAYTCSNGGTCYDSGDTFRCACPP 740
Query: 2364 LYSGKLCQFA---SCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
+ G C A SC NPC NG TCV SG C+C G G CT N P
Sbjct: 741 GWKGSTCAVAKNSSCLPNPCVNGGTCV-GSGASFSCICRDGWEGRTCTHNTNDCNP 795
Score = 63.2 bits (152), Expect = 4e-09
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 33/114 (28%)
Query: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP----------------- 2654
S C C NGGTC+ SG S C C GW+G CT + C+P
Sbjct: 753 SSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFR 812
Query: 2655 ----------------EHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQAL 2692
+ C+ GATC+ +GY C CP G G C++ +
Sbjct: 813 CECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 866
Score = 62.4 bits (150), Expect = 7e-09
Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 2609 CHASP--CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETV-STCDPEHDPPHHCSRG 2665
CH+ C C NGGTC +SG + C C GWKGS C S+C P+ C G
Sbjct: 709 CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC-----LPNPCVNG 763
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
TC+ ++C C G G C + +P
Sbjct: 764 GTCVGSGASFSCICRDGWEGRTCTHNTNDCNP 795
Score = 60.5 bits (145), Expect = 3e-08
Identities = 30/82 (36%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Q A+ C C N +C YC+C GWKG C V+ C + C G T
Sbjct: 421 QLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ------CQHGGT 474
Query: 2668 CISLPHGYTCFCPLGTTGIYCE 2689
C L +GY C CP G G +CE
Sbjct: 475 CKDLVNGYQCVCPRGFGGRHCE 496
Score = 59.7 bits (143), Expect = 4e-08
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
P+G+ +GR+ + + C+ C NGG+C E + C+C +GW G C + C
Sbjct: 336 PDGY--SGRNCEKAEHA-CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDEC--- 389
Query: 2656 HDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
+ C+ G TC+ G+ C CP G C+
Sbjct: 390 --ASNPCAAGGTCVDQVDGFECICPEQWVGATCQ 421
Score = 59.3 bits (142), Expect = 6e-08
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYS 2936
AC N C NGG C + F C C W+G TC + C +N C C+ DQ +
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCV-DQVDGFE 408
Query: 2937 CLCTLGWVGRYCE 2949
C+C WVG C+
Sbjct: 409 CICPEQWVGATCQ 421
Score = 56.2 bits (134), Expect = 5e-07
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL-CLHQSL 2926
GS ++C N C NGG C +G +FSC C W G TC + + N L C + +
Sbjct: 744 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 803
Query: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
C+ ++ + C C G+ G C
Sbjct: 804 CVDGVNW-FRCECAPGFAGPDC 824
Score = 55.1 bits (131), Expect = 1e-06
Identities = 36/106 (33%), Positives = 49/106 (46%), Gaps = 11/106 (10%)
Query: 2589 HFRGLGNPEGH----PNAGRSVGQCHAS--PCSLMKCGNGGTCIESGTSVYCNCTTGWKG 2642
H R + P G+ ++G + CH + C C NGGTCI+ + C C +GW+G
Sbjct: 609 HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 668
Query: 2643 SFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYC 2688
C + C P DP H SRG C L + + C C G G C
Sbjct: 669 ELCDTNPNDCLP--DPCH--SRG-RCYDLVNDFYCACDDGWKGKTC 709
Score = 55.1 bits (131), Expect = 1e-06
Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 2344 CRNNGTCISDNENLF-CECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVCLCPY 2400
C N G C+ D N F CEC ++G C+ C+++PC GATCV + C CP
Sbjct: 798 CYNGGICV-DGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEIN-GYRCSCPP 855
Query: 2401 GRSGPLCTDAINITQPRFSGTDAFGYTS 2428
GR+GP C + I + +S F + S
Sbjct: 856 GRAGPRCQEVIGFGRSCWSRGTPFPHGS 883
Score = 54.7 bits (130), Expect = 1e-06
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 8/70 (11%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL-PHGYTCFCPL 2681
G+C+E CNC T W G C + ++ C H C+ G TCI+ P Y C CP
Sbjct: 285 GSCVEPWQ---CNCETNWGGLLCDKDLNYCGSHHP----CTNGGTCINAEPDQYRCTCPD 337
Query: 2682 GTTGIYCEQA 2691
G +G CE+A
Sbjct: 338 GYSGRNCEKA 347
Score = 53.9 bits (128), Expect = 2e-06
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 2333 NCHVPWC-AHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPK 2389
NCH+ C++ GTC C CPR + G+ C+ C ++PC +G C
Sbjct: 457 NCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDL 516
Query: 2390 SGTDIVCLCPYGRSGPLCTDAINITQP 2416
+ C CP G SGPLC +++ +P
Sbjct: 517 AD-GFHCHCPQGFSGPLCEVDVDLCEP 542
Score = 53.9 bits (128), Expect = 2e-06
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
CA C + G C + C CP+ +SG LC+ CE +PC NGA C G D C
Sbjct: 502 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG-DYYC 560
Query: 2397 LCPYGRSGPLCT 2408
CP G C+
Sbjct: 561 ACPDDFGGKNCS 572
Score = 53.5 bits (127), Expect = 3e-06
Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 7/89 (7%)
Query: 2609 CHASP--CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGA 2666
C +P C C + G C + YC C GWKG C CD + CS G
Sbjct: 671 CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCD-----AYTCSNGG 725
Query: 2667 TCISLPHGYTCFCPLGTTGIYCEQALSIS 2695
TC + C CP G G C A + S
Sbjct: 726 TCYDSGDTFRCACPPGWKGSTCAVAKNSS 754
Score = 52.4 bits (124), Expect = 7e-06
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 2619 CGNGGTCI-ESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
CG G C+ + G + C C +G+ G++C E + C + C G TCI + C
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP-----CRNGGTCIDEVDAFRC 660
Query: 2678 FCPLGTTGIYCE 2689
FCP G G C+
Sbjct: 661 FCPSGWEGELCD 672
Score = 52.0 bits (123), Expect = 9e-06
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C+ C +GG C + +C+C G+ G C V C+P C GA C +L
Sbjct: 502 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPS-----PCRNGARCYNLEG 556
Query: 2674 GYTCFCPLGTTGIYC 2688
Y C CP G C
Sbjct: 557 DYYCACPDDFGGKNC 571
Score = 51.2 bits (121), Expect = 2e-05
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
N+ DC G CRNGG C F C C W G C+ + + CL + C + C
Sbjct: 636 NIDDCLG-----QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCY 690
Query: 2929 PDQSFSYSCLCTLGWVGRYCENK 2951
D + C C GW G+ C ++
Sbjct: 691 -DLVNDFYCACDDGWKGKTCHSR 712
Score = 50.8 bits (120), Expect = 2e-05
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 2875 DGTACGYNT-------CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSL 2926
+G C +NT C NGG C F C C P +AG C ++ C ++ C + +
Sbjct: 782 EGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGAT 841
Query: 2927 CIPDQSFSYSCLCTLGWVGRYCENKTSF 2954
C+ D+ Y C C G G C+ F
Sbjct: 842 CV-DEINGYRCSCPPGRAGPRCQEVIGF 868
Score = 50.1 bits (118), Expect = 4e-05
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFS 2934
D C C N C + C C+P W G C+ +V+ C H C D
Sbjct: 423 DANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTC-KDLVNG 481
Query: 2935 YSCLCTLGWVGRYCE 2949
Y C+C G+ GR+CE
Sbjct: 482 YQCVCPRGFGGRHCE 496
Score = 50.1 bits (118), Expect = 4e-05
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 5/81 (6%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
+C +GGTC + C C G+ G C C C G C L G+ C
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP-----CHSGGLCEDLADGFHC 522
Query: 2678 FCPLGTTGIYCEQALSISDPS 2698
CP G +G CE + + +PS
Sbjct: 523 HCPQGFSGPLCEVDVDLCEPS 543
Score = 49.7 bits (117), Expect = 5e-05
Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGAT 2385
G+N E C + C N G+C C CP +SG C C +NPC G T
Sbjct: 341 GRNCEKAEHA-CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGT 399
Query: 2386 CVPKSGTDIVCLCPYGRSGPLC 2407
CV + C+CP G C
Sbjct: 400 CVDQV-DGFECICPEQWVGATC 420
Score = 46.6 bits (109), Expect = 4e-04
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 2868 GSNVGD-CDGTACGYNTCRNGGECTVN-GTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQ 2924
GS+ G GTA C G C G FSC C + G C++++ CL C +
Sbjct: 590 GSDAGPGMPGTAAS-GVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG 648
Query: 2925 SLCIPDQSFSYSCLCTLGWVGRYCE 2949
CI D+ ++ C C GW G C+
Sbjct: 649 GTCI-DEVDAFRCFCPSGWEGELCD 672
Score = 46.6 bits (109), Expect = 4e-04
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 2334 CH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPK 2389
CH + C CRN GTCI + + C CP + G+LC C +PC + C
Sbjct: 633 CHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 692
Query: 2390 SGTDIVCLCPYGRSGPLC 2407
D C C G G C
Sbjct: 693 V-NDFYCACDDGWKGKTC 709
Score = 44.7 bits (104), Expect = 0.001
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 3/76 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
CA + C GTC+ + C CP + G CQ + CE PC N +C G C
Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIG-GYYC 447
Query: 2397 LCPYGRSGPLCTDAIN 2412
C G G C +N
Sbjct: 448 DCIPGWKGINCHINVN 463
Score = 43.9 bits (102), Expect = 0.003
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTD-IV 2395
C + C N GTC+ + C C + G+ C + C PC NG CV G +
Sbjct: 755 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV--DGVNWFR 812
Query: 2396 CLCPYGRSGPLCTDAINITQPRFSGTDAFGYT 2427
C C G +GP C INI + + S A+G T
Sbjct: 813 CECAPGFAGPDC--RINIDECQ-SSPCAYGAT 841
Score = 41.6 bits (96), Expect = 0.013
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 2337 PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASC-ENNPCGNGATCVPKSGTD 2393
P C H G+C+ E C C + G LC C ++PC NG TC+
Sbjct: 280 PGCVH------GSCV---EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ 330
Query: 2394 IVCLCPYGRSGPLCTDA 2410
C CP G SG C A
Sbjct: 331 YRCTCPDGYSGRNCEKA 347
Score = 40.0 bits (92), Expect = 0.036
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 15/84 (17%)
Query: 2876 GTACGYNTCRNG-----GECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPD 2930
G C C+ G G CTV G CRC W G C++ V C+H S P
Sbjct: 237 GKECKEAVCKQGCNLLHGGCTVPG---ECRCSYGWQGRFCDECVPYPG--CVHGSCVEP- 290
Query: 2931 QSFSYSCLCTLGWVGRYCENKTSF 2954
+ C C W G C+ ++
Sbjct: 291 ----WQCNCETNWGGLLCDKDLNY 310
Score = 40.0 bits (92), Expect = 0.036
Identities = 27/104 (25%), Positives = 35/104 (33%), Gaps = 24/104 (23%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-----------ETVSTCDP 2654
V C SPC NG C YC C + G C+ + C
Sbjct: 537 VDLCEPSPCR-----NGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGS 591
Query: 2655 EHDP-------PHHCSRGATCISLPHG-YTCFCPLGTTGIYCEQ 2690
+ P C C+S P G ++C C G TG YC +
Sbjct: 592 DAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHE 635
Score = 39.3 bits (90), Expect = 0.062
Identities = 20/47 (42%), Positives = 23/47 (48%), Gaps = 5/47 (10%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPS 2149
C CH+GG C L+ G F C CP F+G CE D L PS
Sbjct: 502 CASSPCHSGGLCED--LADG---FHCHCPQGFSGPLCEVDVDLCEPS 543
Score = 39.3 bits (90), Expect = 0.062
Identities = 23/102 (22%), Positives = 35/102 (34%), Gaps = 25/102 (24%)
Query: 2336 VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF----------------------- 2372
V C CRN C + + +C CP + GK C
Sbjct: 537 VDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPG 596
Query: 2373 --ASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
+ + CG CV + G + C+C G +G C + I+
Sbjct: 597 MPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID 638
Score = 38.9 bits (89), Expect = 0.081
Identities = 21/100 (21%), Positives = 34/100 (34%), Gaps = 24/100 (24%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN--------------------- 2911
+ D C + CRNG C + C C D+ G C+
Sbjct: 534 EVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDA 593
Query: 2912 ---QSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
+ + +C C+ ++SC+C G+ G YC
Sbjct: 594 GPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC 633
Score = 37.7 bits (86), Expect = 0.18
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 2901 CLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
C+ W G C ++V LH +P + C C+ GW GR+C+
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGE-----CRCSYGWQGRFCD 274
Score = 37.7 bits (86), Expect = 0.18
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 2897 FSCRCLPDWAGNTCNQSVSCL--NNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSF 2954
+ C C +W G C++ ++ ++ C + CI + Y C C G+ GR CE
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Query: 2955 STAKFMGN 2962
T+ N
Sbjct: 351 CTSNPCAN 358
Score = 36.2 bits (82), Expect = 0.53
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK--DAGLFFPSFNGNSYLELP 2159
C NGGTC +++ ++C CP ++GR CEK A P NG S E+P
Sbjct: 317 CTNGGTC----INAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVP 366
Score = 35.4 bits (80), Expect = 0.90
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
A C + C NGG+CH + SG F+C CP ++G C D
Sbjct: 347 AEHACTSNPCANGGSCHEV--PSG---FECHCPSGWSGPTCALD 385
Score = 34.3 bits (77), Expect = 2.0
Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 2090 WTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLF--F 2147
W + +VA S C + C NGGTC + SG SF C C + GR C +
Sbjct: 742 WKGSTCAVAKNSSCLPNPCVNGGTC----VGSG-ASFSCICRDGWEGRTCTHNTNDCNPL 796
Query: 2148 PSFNG 2152
P +NG
Sbjct: 797 PCYNG 801
Score = 33.5 bits (75), Expect = 3.4
Identities = 19/71 (26%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C + C +GG C F C C ++G C V C + C + + C + Y C
Sbjct: 502 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCY-NLEGDYYC 560
Query: 2938 LCTLGWVGRYC 2948
C + G+ C
Sbjct: 561 ACPDDFGGKNC 571
Score = 32.7 bits (73), Expect = 5.8
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 5/33 (15%)
Query: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
C +GGTC + + +QC CP F GR CE
Sbjct: 469 CQHGGTCKDL-----VNGYQCVCPRGFGGRHCE 496
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 398 bits (1022), Expect = e-110
Identities = 214/642 (33%), Positives = 300/642 (46%), Gaps = 72/642 (11%)
Query: 667 RKCVPGFKGTQCEIDIDECASHP----CKNGATCIDQ---PGNYFCQCVPPFKVVDG--- 716
+ C+ G+ G +C I P CK C Q G Y +C+P V G
Sbjct: 218 KTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICN 277
Query: 717 --FSCLCNPGYVGIRCEQDIDDCILNA-CEHNSTCKDLHLS-YQCVCLSDWEGNFCEQES 772
+ CLC + G C++D++ C + C + TC + YQC C + G CE
Sbjct: 278 EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAE 337
Query: 773 NECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQ 832
+ C +PC N +C + + CEC+ GWTG CS I++C + C +GG C + +
Sbjct: 338 HACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQD--LVNG 395
Query: 833 FVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVK 892
F C+CPP +TG+ C N C+ PC N +C L+ A+ +C C + G+NC+I++
Sbjct: 396 FKCVCPPQWTGKTCQLDANECEA--KPCVNAKSCKNLI-ASYYCDCLPGWMGQNCDININ 452
Query: 893 DCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFC 952
DCL CQ+ C D+VN +RCIC PG++G CE +I+EC+S PC N G C + NRF C
Sbjct: 453 DCLG-QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQC 511
Query: 953 NCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEP 1012
C + G C+LD++ C+ +PC + C R Y C C Y G NC D C + P
Sbjct: 512 LCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTP 571
Query: 1013 CLHDGVCI---------DGINH-------------------YTCDCKSGFFGTHCETNAN 1044
C C +G+ + +TCDC GF GT+C N N
Sbjct: 572 CEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN 631
Query: 1045 DCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTC 1103
DC SNPC +G C + +N Y C C C+ INDC+ PC N G C+ + F C
Sbjct: 632 DCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Query: 1104 ICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININ 1163
C G+ G C C E C NGG C D G F C C G+ G C I N
Sbjct: 692 DCKNGWKGKTCHSRDSQCDE-----ATCNNGGTCYD-EGDAFKCMCPGGWEGTTCNIARN 745
Query: 1164 E-CSSSPCLHGADCEDHINGYVCKCQPGWSGHHC-ENELECIPNSCVHE-LCMENEPGST 1220
C +PC +G C + + C C+ GW G C +N +C P+ C + C++ +
Sbjct: 746 SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYR 805
Query: 1221 CLCTPGF--------------MTCSIGLLCGDEIRRITCLTP 1248
C C PGF C+ G C DEI C+ P
Sbjct: 806 CECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Score = 396 bits (1018), Expect = e-109
Identities = 199/646 (30%), Positives = 295/646 (45%), Gaps = 89/646 (13%)
Query: 646 DCKSASCKNGTTSTH--------------LRGYFFRKCVP-------------------G 672
+C A C+ G + H +G + KC+P
Sbjct: 228 ECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETN 287
Query: 673 FKGTQCEIDIDECASH-PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCE 731
+ G C+ D++ C +H PC NG TC + D + C C GY G CE
Sbjct: 288 WGGQLCDKDLNYCGTHQPCLNGGTCSNTGP-------------DKYQCSCPEGYSGPNCE 334
Query: 732 QDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYK 791
C+ + C + +CK+ L ++C C W G C ++C N C + TC DL
Sbjct: 335 IAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVN 394
Query: 792 SYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYN 851
++C C WTG+ C + NEC++ PC+N C + + C C P + GQ C N
Sbjct: 395 GFKCVCPPQWTGKTCQLDANECEAKPCVNAKSC--KNLIASYYCDCLPGWMGQNCDININ 452
Query: 852 LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNN 911
C C+N+++C LV+ + CIC + G +CE D+ +C C + G C++ +N
Sbjct: 453 DC---LGQCQNDASCRDLVNGYR-CICPPGYAGDHCERDIDECASNPCLNGGHCQNEINR 508
Query: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK 971
F+C+C GFSG+LC+++I+ C PC+N C + + +FC C +Y G C + C+
Sbjct: 509 FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Query: 972 ISPCLDEENCVYRTDG----------------------------YNCLCAPGYTGINCEI 1003
+PC ++C + C C G+TG C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 1004 NLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINE 1062
N+++C S PC + G CIDG+N Y C C G+ G +CETN NDC NPC +G C +L+N+
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND 688
Query: 1063 YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCA 1122
+ C C C + + C C N G C F C+CP G+ G C + ++
Sbjct: 689 FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC 748
Query: 1123 EPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHING 1182
P C NGG CV G +F C C G+ G C N N+CS PC + C D N
Sbjct: 749 LPNP----CHNGGTCVVN-GESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNW 803
Query: 1183 YVCKCQPGWSGHHCE-NELECIPNSCVH-ELCMENEPGSTCLCTPG 1226
Y C+C PG++G C N EC + C C++ G C+C PG
Sbjct: 804 YRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPG 849
Score = 372 bits (955), Expect = e-102
Identities = 225/751 (29%), Positives = 333/751 (44%), Gaps = 92/751 (12%)
Query: 518 EDNNSSC---WFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENE 574
++ N +C W E + IC GCS C W G +Y +
Sbjct: 214 QNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQG-LYCDKCIPHPG-- 270
Query: 575 CQHEAVCKDEINRP-RCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALS----HNCNC 629
C H +C N P +C C ++ G+LC +++YC G H ++G + + + C+C
Sbjct: 271 CVH-GIC----NEPWQCLCETNWGGQLCDKDLNYC-GTHQPCLNGGTCSNTGPDKYQCSC 324
Query: 630 SGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHP 689
+ Y CEI C S C N + F +C PG+ G C +ID+C+ +
Sbjct: 325 P--EGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 690 CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCK 749
C +G TC D +V+GF C+C P + G C+ D ++C C + +CK
Sbjct: 383 CSHGGTCQD--------------LVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCK 428
Query: 750 DLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEE 809
+L SY C CL W G C+ N+C + C+N+++C DL YRC C G+ G +C +
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDC-LGQCQNDASCRDLVNGYRCICPPGYAGDHCERD 487
Query: 810 INECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLAL 869
I+EC S+PC+NGG C +F CLCP ++G C + C+ NPC+N + C
Sbjct: 488 IDECASNPCLNGGHCQNEI--NRFQCLCPTGFSGNLCQLDIDYCE--PNPCQNGAQCYNR 543
Query: 870 VDANQHCICREEFEGKNCEIDVKDCLFLSCQ---------------------------DY 902
++ C C E++EGKNC C C+ +
Sbjct: 544 A-SDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH 602
Query: 903 GDCEDMVNN-FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGP 961
G C+ F C C GF+G+ C IN+C S PC+N GTC+D N + C C + G
Sbjct: 603 GKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGA 662
Query: 962 FCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCID 1021
+CE ++N C +PC + C + + C C G+ G C +C C + G C D
Sbjct: 663 YCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYD 722
Query: 1022 GINHYTCDCKSGFFGTHCETNAN-DCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIK 1079
+ + C C G+ GT C N CL NPC + G C + C C C
Sbjct: 723 EGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN 782
Query: 1080 INDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVD 1139
NDC+ PC N G C + + C C G+ G C +I+ C S C G CVD
Sbjct: 783 TNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININEC-----QSSPCAFGATCVD 837
Query: 1140 GPGHTFDCRCLPGFSGQFCEININECSSSPCL-------HGADCEDHINGYVCKCQPGWS 1192
+ + C C PG SG C+ E S PC+ GA +D N C+C +
Sbjct: 838 -EINGYRCVCPPGHSGAKCQ----EVSGRPCITMGSVIPDGAKWDDDCN--TCQC---LN 887
Query: 1193 GHHCENELECIPNSC-VHELCMENEPGSTCL 1222
G +++ C P C +H+ E G +C+
Sbjct: 888 GRIACSKVWCGPRPCLLHKGHSECPSGQSCI 918
Score = 310 bits (795), Expect = 1e-83
Identities = 217/759 (28%), Positives = 306/759 (40%), Gaps = 140/759 (18%)
Query: 378 PLRNNATCKK--------CEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNII 429
P N A C++ C+ C C G+ C+K I H + C NE W
Sbjct: 227 PECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGIC-NEPW----- 280
Query: 430 GRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGV----TFHGICQDKGPAQFEYVWQLGF 485
C+ C N W L + L YCG G C + GP +++ G+
Sbjct: 281 -----QCL--CETN--W---GGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
Query: 486 AGSEGEKCQ-GVIDAYFFLAANCTEDA-----------------TYVNDPEDNNSSCWFP 527
+G E + + +C E + T ++D NN S
Sbjct: 329 SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCS---- 384
Query: 528 HEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINR 587
H GT + NG C+ C +W G + + + C + CK+ I
Sbjct: 385 HGGTCQDLVNGFKCV-----------CPPQWTGKTCQLDANECEAKPCVNAKSCKNLIAS 433
Query: 588 PRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDC 647
C C ++G+ C +N++ CLG L + C C Y + CE D ++C
Sbjct: 434 YYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICP--PGYAGDHCERDIDEC 491
Query: 648 KSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQC 707
S C NG + F C GF G C++DID C +PC+NGA C ++ +YFC+C
Sbjct: 492 ASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKC 551
Query: 708 -----------------VPPFKVVDG---------------------------------- 716
P +V+D
Sbjct: 552 PEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG 611
Query: 717 -FSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNEC 775
F+C CN G+ G C ++I+DC N C + TC D SY+C+C WEG +CE N+C
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDC 671
Query: 776 KMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVC 835
NPC N TC DL + C+C +GW G+ C ++CD C NGG C++ F C
Sbjct: 672 SQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDE--GDAFKC 729
Query: 836 LCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCL 895
+CP + G C+ N L NPC N TC+ ++ C+C+E +EG C + DC
Sbjct: 730 MCPGGWEGTTCNIARN-SSCLPNPCHNGGTCVVNGESFT-CVCKEGWEGPICAQNTNDCS 787
Query: 896 FLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCE 955
C + G C D N +RC C PGF+G C I INEC S PC TCVD N + C C
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCP 847
Query: 956 PEYHGPFC-ELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPC- 1013
P + G C E+ C + + + D C C G I C + C PC
Sbjct: 848 PGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNG--RIAC--SKVWCGPRPCL 903
Query: 1014 LHDGVCIDGINHYTCDCKSGFFGTHCETNAND-CLSNPC 1051
LH G H C G C +D C +PC
Sbjct: 904 LHKG-------HSECPS-----GQSCIPILDDQCFVHPC 930
Score = 297 bits (760), Expect = 1e-79
Identities = 196/685 (28%), Positives = 290/685 (42%), Gaps = 66/685 (9%)
Query: 174 CQESLSSEFCSG-HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKR 232
C ++ + CS HG C C CQ + G YC D C P +G C
Sbjct: 229 CNRAICRQGCSPKHGSCKLPG-----DCRCQYGWQGLYC---DKCIPHPGCVHGIC---- 276
Query: 233 ENWDEQAYECVCHPPFTGKNCSEIIGQCQPHV-CFHGN-CSNITSNSFICECDEQFSGPF 290
+ ++C+C + G+ C + + C H C +G CSN + + C C E +SGP
Sbjct: 277 ----NEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN 332
Query: 291 CEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKI 350
CE++ C+S RG C +S + EC G + T++ + S C +G C +
Sbjct: 333 CEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDL 392
Query: 351 SNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAID 410
N C+C P +T C+ CE+ P N +CK Y C C+ G+ +NC+ I+
Sbjct: 393 VNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININ 452
Query: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQ 470
C C N+ C +++ ++ +C PG + C +++ + C G G CQ
Sbjct: 453 DC---LGQCQNDASCRDLVNGYRCICPPGYAGDHC--ERDIDECASNPCLNG----GHCQ 503
Query: 471 DKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEG 530
++ +F+ + GF+G+ CQ +D + C A N D C +EG
Sbjct: 504 NE-INRFQCLCPTGFSGN---LCQ--LDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEG 557
Query: 531 TKEICANGCSCLSEE---DSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEI-N 586
CS L + E C + A N E N C CK +
Sbjct: 558 ------KNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG 611
Query: 587 RPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCL--ALSHNCNCSGLQRYERNICEIDT 644
+ C C+ + G C N++ C N + G C+ S+ C CS +E CE +
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRN-GGTCIDGVNSYKCICS--DGWEGAYCETNI 668
Query: 645 EDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYF 704
DC C NG T L F+ C G+KG C +C C NG TC D+
Sbjct: 669 NDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG---- 724
Query: 705 CQCVPPFKVVDGFSCLCNPGYVGIRCE-QDIDDCILNACEHNSTCKDLHLSYQCVCLSDW 763
D F C+C G+ G C C+ N C + TC S+ CVC W
Sbjct: 725 ----------DAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGW 774
Query: 764 EGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGL 823
EG C Q +N+C +PC N+ TC D YRCEC G+ G +C INEC S PC G
Sbjct: 775 EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGAT 834
Query: 824 CHESTIPGQFVCLCPPLYTGQFCHQ 848
C + + C+CPP ++G C +
Sbjct: 835 CVDEI--NGYRCVCPPGHSGAKCQE 857
Score = 241 bits (616), Expect = 6e-63
Identities = 144/514 (28%), Positives = 219/514 (42%), Gaps = 73/514 (14%)
Query: 747 TCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC 806
TC D + + C FC + C N T C GW G C
Sbjct: 186 TCDDYYYGFGC-------NKFCRPRDDFFGHYACDQNGNKT---------CMEGWMGPEC 229
Query: 807 SEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTC 866
+ I C G C +PG C C + G +C + +H C C
Sbjct: 230 NRAI--CRQGCSPKHGSCK---LPGD--CRCQYGWQGLYCDKCIPHPGCVHGICNEPWQC 282
Query: 867 LALVDANQHCICREEFEGKNCEIDVKDC-LFLSCQDYGDCEDM-VNNFRCICRPGFSGSL 924
L C + G+ C+ D+ C C + G C + + ++C C G+SG
Sbjct: 283 L----------CETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPN 332
Query: 925 CEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYR 984
CEI + C S+PC N G+C + + F C C P + GP C +++ C + C C
Sbjct: 333 CEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDL 392
Query: 985 TDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNAN 1044
+G+ C+C P +TG C+++ +EC ++PC++ C + I Y CDC G+ G +C+ N N
Sbjct: 393 VNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININ 452
Query: 1045 DCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCI 1104
DCL C +L+N Y C C C+ I++C S PC+N G CQ + F C+
Sbjct: 453 DCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCL 512
Query: 1105 CPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININE 1164
CP G++G C+ ID C EP C NG C + F C+C + G+ C +
Sbjct: 513 CPTGFSGNLCQLDIDYC-EPN----PCQNGAQCYNRASDYF-CKCPEDYEGKNCSHLKDH 566
Query: 1165 CSSSPC----------------------------LHGADCEDHING-YVCKCQPGWSGHH 1195
C ++PC HG C+ G + C C G++G +
Sbjct: 567 CRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHG-KCKSQSGGKFTCDCNKGFTGTY 625
Query: 1196 C-ENELECIPNSCVH-ELCMENEPGSTCLCTPGF 1227
C EN +C N C + C++ C+C+ G+
Sbjct: 626 CHENINDCESNPCRNGGTCIDGVNSYKCICSDGW 659
Score = 149 bits (375), Expect = 6e-35
Identities = 141/589 (23%), Positives = 214/589 (36%), Gaps = 96/589 (16%)
Query: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDA--CSFKPCKNNGSCINKRE 233
+ S CS G C + + C C P ++GK CQ LDA C KPC N SC N
Sbjct: 376 DDCSPNNCSHGGTC--QDLVNGFKCVCPPQWTGKTCQ-LDANECEAKPCVNAKSCKNLIA 432
Query: 234 NWDEQAYECVCHPPFTGKNC----SEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
+ Y C C P + G+NC ++ +GQCQ +C ++ N + C C ++G
Sbjct: 433 S-----YYCDCLPGWMGQNCDININDCLGQCQNDA----SCRDLV-NGYRCICPPGYAGD 482
Query: 290 FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK 349
CE C S G C N + + CP G S + D+ PCQNG C
Sbjct: 483 HCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYN 542
Query: 350 ISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCK----------------------- 386
++D C C + C ++ C + P +C
Sbjct: 543 RASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPH 602
Query: 387 -KCEKD----YPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCT 441
KC+ + C C GFT C + I+ C+ S C N C + + +K +C G
Sbjct: 603 GKCKSQSGGKFTCDCNKGFTGTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGWE 660
Query: 442 KNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYF 501
C N+ Q+ C+ G T + D + W+ S +C
Sbjct: 661 GAYCE--TNINDCSQNPCHNGGTCRDLVNDFY-CDCKNGWKGKTCHSRDSQCD------- 710
Query: 502 FLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEE---------DSQEYRY 552
A C T ++ + C EGT A SCL + + +
Sbjct: 711 --EATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTC 768
Query: 553 LCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNH 612
+C W G + +NT D + C + C D N RC C+ + G C +N++ C +
Sbjct: 769 VCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSS- 827
Query: 613 SISVHGLCL--ALSHNCNC----SGLQRYERNICEIDT------------EDCKSASCKN 654
+ C+ + C C SG + E + T +DC + C N
Sbjct: 828 PCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Query: 655 GTTSTHLRGYFFRKCVPGFKGTQCE-------IDIDECASHPCKNGATC 696
G + R C+ ++C I D+C HPC C
Sbjct: 888 GRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGEC 936
Score = 67.0 bits (162), Expect = 3e-10
Identities = 34/98 (34%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 2324 EARHGKNIENCHV--PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA---SCENN 2378
+ ++G + CH C C N GTC + + C CP + G C A SC N
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 2379 PCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
PC NG TCV +G C+C G GP+C N P
Sbjct: 752 PCHNGGTCV-VNGESFTCVCKEGWEGPICAQNTNDCSP 788
Score = 66.6 bits (161), Expect = 4e-10
Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 2596 PEGH--PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653
PEG+ PN + C + PC N G+C E+ C C+ GW G C+ + C
Sbjct: 325 PEGYSGPNCEIAEHACLSDPCH-----NRGSCKETSLGFECECSPGWTGPTCSTNIDDCS 379
Query: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
P++CS G TC L +G+ C CP TG C+
Sbjct: 380 -----PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410
Score = 65.5 bits (158), Expect = 8e-10
Identities = 30/77 (38%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN--QSVSCLNNLCLHQSLCIPDQSFSYS 2936
C TC NGG C G F C C W G TCN ++ SCL N C + C+ + S++
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFT 767
Query: 2937 CLCTLGWVGRYCENKTS 2953
C+C GW G C T+
Sbjct: 768 CVCKEGWEGPICAQNTN 784
Score = 64.7 bits (156), Expect = 1e-09
Identities = 31/88 (35%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+ + + CS C NGGTC + YC+C GWKG C S CD C+ G T
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA-----TCNNGGT 719
Query: 2668 CISLPHGYTCFCPLGTTGIYCEQALSIS 2695
C + C CP G G C A + S
Sbjct: 720 CYDEGDAFKCMCPGGWEGTTCNIARNSS 747
Score = 63.2 bits (152), Expect = 4e-09
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Query: 2601 NAGRSVGQCHAS--PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDP 2658
N G + CH + C C NGGTCI+ S C C+ GW+G++C ++ C
Sbjct: 618 NKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCS----- 672
Query: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSN 2702
+ C G TC L + + C C G G C S D + +N
Sbjct: 673 QNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNN 716
Score = 63.2 bits (152), Expect = 4e-09
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
S C C NGGTC+ +G S C C GW+G C + + C PH C TC+
Sbjct: 746 SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCS-----PHPCYNSGTCVDG 800
Query: 2672 PHGYTCFCPLGTTGIYC 2688
+ Y C C G G C
Sbjct: 801 DNWYRCECAPGFAGPDC 817
Score = 62.4 bits (150), Expect = 7e-09
Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 2609 CHA--SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-ETVSTCDPEHDPPHHCSRG 2665
CH+ S C C NGGTC + G + C C GW+G+ C S+C P+ C G
Sbjct: 702 CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC-----LPNPCHNG 756
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
TC+ +TC C G G C Q + P
Sbjct: 757 GTCVVNGESFTCVCKEGWEGPICAQNTNDCSP 788
Score = 61.6 bits (148), Expect = 1e-08
Identities = 83/308 (26%), Positives = 113/308 (36%), Gaps = 59/308 (19%)
Query: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE--KDAGLFFPSFNGNSYLELPFLKFVL 2165
C NGGTC ++G +QC CP ++G CE + A L P N S E L F
Sbjct: 306 CLNGGTCS----NTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETS-LGFEC 360
Query: 2166 EKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTV 2225
E T T TN I + NNC G Q+++
Sbjct: 361 ECSPGWTGP---TCSTN-----IDDCSPNNCSHG-----------------GTCQDLV-- 393
Query: 2226 SANYSINTNAFTPITIRYTTPVGSPGVVCMIEMT-ADGKPPVQKKDTEISHASQAYFESM 2284
N F + P G C ++ + KP V K + AS Y+
Sbjct: 394 --------NGF-----KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIAS--YYCDC 438
Query: 2285 FLGHIPAN--VQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHH 2342
G + N + I+ G C + N I G + E + CA +
Sbjct: 439 LPGWMGQNCDININDCLGQCQNDASC---RDLVNGYRCICPPGYAGDHCER-DIDECASN 494
Query: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPY 2400
C N G C ++ C CP +SG LCQ CE NPC NGA C ++ +D C CP
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRA-SDYFCKCPE 553
Query: 2401 GRSGPLCT 2408
G C+
Sbjct: 554 DYEGKNCS 561
Score = 60.8 bits (146), Expect = 2e-08
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Q A+ C C N +C S YC+C GW G C ++ C + C A+
Sbjct: 410 QLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQ------CQNDAS 463
Query: 2668 CISLPHGYTCFCPLGTTGIYCEQ 2690
C L +GY C CP G G +CE+
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCER 486
Score = 58.9 bits (141), Expect = 8e-08
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
G G+ ++C N C NGG C VNG +F+C C W G C Q+ + C + C
Sbjct: 733 GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792
Query: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYC 2948
+ C+ ++ Y C C G+ G C
Sbjct: 793 NSGTCVDGDNW-YRCECAPGFAGPDC 817
Score = 58.2 bits (139), Expect = 1e-07
Identities = 27/73 (36%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVC 2396
C+ H C N+GTC+ + CEC ++G C+ C+++PC GATCV + C
Sbjct: 786 CSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEI-NGYRC 844
Query: 2397 LCPYGRSGPLCTD 2409
+CP G SG C +
Sbjct: 845 VCPPGHSGAKCQE 857
Score = 57.8 bits (138), Expect = 2e-07
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYS 2936
AC + C N G C F C C P W G TC+ ++ C N C H C D +
Sbjct: 339 ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTC-QDLVNGFK 397
Query: 2937 CLCTLGWVGRYCENKTSFSTAK 2958
C+C W G+ C+ + AK
Sbjct: 398 CVCPPQWTGKTCQLDANECEAK 419
Score = 57.0 bits (136), Expect = 3e-07
Identities = 73/325 (22%), Positives = 119/325 (36%), Gaps = 48/325 (14%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLK 2162
C + C +GGTC + + F+C CP +TG+ C+ DA E
Sbjct: 378 CSPNNCSHGGTCQDL-----VNGFKCVCPPQWTGKTCQLDAN------------ECEAKP 420
Query: 2163 FVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLH----LFLVEGR----PSVKY 2214
V K + Y G N N+C Q + LV G P
Sbjct: 421 CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA 480
Query: 2215 GCGNSQNILTVSANYSINTNAFTPITIRY--TTPVGSPGVVCMIEMTADGKPPVQKKDTE 2272
G ++I ++N +N R+ P G G +C +++ P Q
Sbjct: 481 GDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQC 540
Query: 2273 ISHASQAYFE--SMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKN 2330
+ AS + + + G ++++ H + P C + + N + G
Sbjct: 541 YNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN--------DTPEG-- 590
Query: 2331 IENCHVPWCAHHLCRNNGTCISDNENLF-CECPRLYSGKLC--QFASCENNPCGNGATCV 2387
V + + ++C +G C S + F C+C + ++G C CE+NPC NG TC+
Sbjct: 591 -----VRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCI 645
Query: 2388 PKSGTDIVCLCPYGRSGPLCTDAIN 2412
C+C G G C IN
Sbjct: 646 -DGVNSYKCICSDGWEGAYCETNIN 669
Score = 57.0 bits (136), Expect = 3e-07
Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 6/72 (8%)
Query: 2619 CGNGGTC-IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
CG G C +SG C+C G+ G++C E ++ C E +P C G TCI + Y C
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC--ESNP---CRNGGTCIDGVNSYKC 653
Query: 2678 FCPLGTTGIYCE 2689
C G G YCE
Sbjct: 654 ICSDGWEGAYCE 665
Score = 56.2 bits (134), Expect = 5e-07
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
C+ + C N GTC + +C+C + GK C + + C+ C NG TC + G C
Sbjct: 671 CSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDE-GDAFKC 729
Query: 2397 LCPYGRSGPLCTDAIN 2412
+CP G G C A N
Sbjct: 730 MCPGGWEGTTCNIARN 745
Score = 55.1 bits (131), Expect = 1e-06
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
N+ DC+ N CRNGG C ++ C C W G C +++ C N C + C
Sbjct: 629 NINDCES-----NPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC- 682
Query: 2929 PDQSFSYSCLCTLGWVGRYCENKTS 2953
D + C C GW G+ C ++ S
Sbjct: 683 RDLVNDFYCDCKNGWKGKTCHSRDS 707
Score = 53.9 bits (128), Expect = 2e-06
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 7/114 (6%)
Query: 2307 GCILDLQVNNKEFFIIDEARHGKNIENCHVPWCA-HHLCRNNGTCISDNENLF-CECPRL 2364
GC+ + N+ + + E G + + + +C H C N GTC + + + C CP
Sbjct: 270 GCVHG--ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEG 327
Query: 2365 YSGKLCQFA--SCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
YSG C+ A +C ++PC N +C ++ C C G +GP C+ I+ P
Sbjct: 328 YSGPNCEIAEHACLSDPCHNRGSC-KETSLGFECECSPGWTGPTCSTNIDDCSP 380
Score = 53.9 bits (128), Expect = 2e-06
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 2882 NTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLC 2939
N C G+C + +G F+C C + G C+++++ C +N C + CI D SY C+C
Sbjct: 597 NVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCI-DGVNSYKCIC 655
Query: 2940 TLGWVGRYCE 2949
+ GW G YCE
Sbjct: 656 SDGWEGAYCE 665
Score = 53.5 bits (127), Expect = 3e-06
Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 7/86 (8%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
GA +N+ DC N C NGG C F C C W G TC+ S C C
Sbjct: 661 GAYCETNINDCS-----QNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCN 715
Query: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYC 2948
+ C D+ ++ C+C GW G C
Sbjct: 716 NGGTCY-DEGDAFKCMCPGGWEGTTC 740
Score = 52.4 bits (124), Expect = 7e-06
Identities = 32/91 (35%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
C + C N GTC+ + E+ C C + G +C C +PC N TCV C
Sbjct: 748 CLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNW-YRC 806
Query: 2397 LCPYGRSGPLCTDAINITQPRFSGTDAFGYT 2427
C G +GP C IN Q S AFG T
Sbjct: 807 ECAPGFAGPDCRININECQ---SSPCAFGAT 834
Score = 51.6 bits (122), Expect = 1e-05
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 10/85 (11%)
Query: 2604 RSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
R + +C ++PC NGG C C C TG+ G+ C + C+ P+ C
Sbjct: 486 RDIDECASNPCL-----NGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCE-----PNPCQ 535
Query: 2664 RGATCISLPHGYTCFCPLGTTGIYC 2688
GA C + Y C CP G C
Sbjct: 536 NGAQCYNRASDYFCKCPEDYEGKNC 560
Score = 50.8 bits (120), Expect = 2e-05
Identities = 28/78 (35%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 2334 CH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPK 2389
CH + C + CRN GTCI + C C + G C+ C NPC NG TC
Sbjct: 626 CHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC-RD 684
Query: 2390 SGTDIVCLCPYGRSGPLC 2407
D C C G G C
Sbjct: 685 LVNDFYCDCKNGWKGKTC 702
Score = 49.7 bits (117), Expect = 5e-05
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C+N+ +C C CP Y+G C+ C +NPC NG C + CLCP G
Sbjct: 458 CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINR-FQCLCPTG 516
Query: 2402 RSGPLCTDAINITQP 2416
SG LC I+ +P
Sbjct: 517 FSGNLCQLDIDYCEP 531
Score = 48.9 bits (115), Expect = 8e-05
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFS 2934
D C C N C ++ C CLP W G C+ +++ C + + C D
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASC-RDLVNG 470
Query: 2935 YSCLCTLGWVGRYCE 2949
Y C+C G+ G +CE
Sbjct: 471 YRCICPPGYAGDHCE 485
Score = 47.4 bits (111), Expect = 2e-04
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 12/83 (14%)
Query: 2870 NVGDCDGTACGYNTCRNGGECT--VNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSL 2926
N+ DC G C+N C VNG + C C P +AG+ C + + C +N CL+
Sbjct: 450 NINDCLGQ------CQNDASCRDLVNG--YRCICPPGYAGDHCERDIDECASNPCLNGGH 501
Query: 2927 CIPDQSFSYSCLCTLGWVGRYCE 2949
C ++ + CLC G+ G C+
Sbjct: 502 C-QNEINRFQCLCPTGFSGNLCQ 523
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 2875 DGTACGYNT-------CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSL 2926
+G C NT C N G C + C C P +AG C +++ C ++ C +
Sbjct: 775 EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGAT 834
Query: 2927 CIPDQSFSYSCLCTLGWVGRYCE 2949
C+ D+ Y C+C G G C+
Sbjct: 835 CV-DEINGYRCVCPPGHSGAKCQ 856
Score = 46.2 bits (108), Expect = 5e-04
Identities = 33/132 (25%), Positives = 48/132 (36%), Gaps = 32/132 (24%)
Query: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGK-------LCQFASCE------ 2376
N+ + +C + C+N C + + FC+CP Y GK C+ CE
Sbjct: 520 NLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Query: 2377 ----------------NNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP---R 2417
+N CG C +SG C C G +G C + IN + R
Sbjct: 580 VAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCR 639
Query: 2418 FSGTDAFGYTSF 2429
GT G S+
Sbjct: 640 NGGTCIDGVNSY 651
Score = 45.4 bits (106), Expect = 9e-04
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C N C NGG C F C C ++GN C + C N C + + C +++ Y C
Sbjct: 491 CASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCY-NRASDYFC 549
Query: 2938 LCTLGWVGRYCEN 2950
C + G+ C +
Sbjct: 550 KCPEDYEGKNCSH 562
Score = 43.5 bits (101), Expect = 0.003
Identities = 26/74 (35%), Positives = 30/74 (40%), Gaps = 12/74 (16%)
Query: 2337 PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASC-ENNPCGNGATCVPKSGTD 2393
P C H +C NE C C + G+LC C + PC NG TC
Sbjct: 269 PGCVHGIC---------NEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDK 319
Query: 2394 IVCLCPYGRSGPLC 2407
C CP G SGP C
Sbjct: 320 YQCSCPEGYSGPNC 333
Score = 41.2 bits (95), Expect = 0.016
Identities = 42/163 (25%), Positives = 58/163 (35%), Gaps = 40/163 (24%)
Query: 2568 DFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIE 2627
D+ GF GC + R + GH+ N G +C+ + C G+C
Sbjct: 189 DYYYGF-GCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKL 247
Query: 2628 SGTSVYCNCTTGWKGSFCTETV------------------------STCDPE------HD 2657
G C C GW+G +C + + CD + H
Sbjct: 248 PGD---CRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQ 304
Query: 2658 PPHHCSRGATCISL-PHGYTCFCPLGTTGIYCEQA--LSISDP 2697
P C G TC + P Y C CP G +G CE A +SDP
Sbjct: 305 P---CLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDP 344
Score = 41.2 bits (95), Expect = 0.016
Identities = 24/103 (23%), Positives = 39/103 (37%), Gaps = 23/103 (22%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-----------ETVSTCD---PEHDPP 2659
C C NG C + +C C ++G C+ E + +C +D P
Sbjct: 529 CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTP 588
Query: 2660 HHCSRGATCISLPHG---------YTCFCPLGTTGIYCEQALS 2693
++ + PHG +TC C G TG YC + ++
Sbjct: 589 EGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN 631
Score = 40.0 bits (92), Expect = 0.036
Identities = 24/107 (22%), Positives = 37/107 (34%), Gaps = 28/107 (26%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV------------SCL 2917
N+ D C N C+NG +C + + C+C D+ G C+ SC
Sbjct: 520 NLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Query: 2918 ----------------NNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
+N+C C ++C C G+ G YC
Sbjct: 580 VAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYC 626
Score = 39.7 bits (91), Expect = 0.048
Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 21/87 (24%)
Query: 2876 GTACGYNTCRNG-----GECTVNGTTFSCRCLPDWAGNTCNQSV---SCLNNLCLHQSLC 2927
G C CR G G C + G CRC W G C++ + C++ +C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPG---DCRCQYGWQGLYCDKCIPHPGCVHGIC------ 276
Query: 2928 IPDQSFSYSCLCTLGWVGRYCENKTSF 2954
+ + CLC W G+ C+ ++
Sbjct: 277 ----NEPWQCLCETNWGGQLCDKDLNY 299
Score = 37.0 bits (84), Expect = 0.31
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 5/37 (13%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
C Q+ CHNGGTC + + F CDC + G+ C
Sbjct: 671 CSQNPCHNGGTCRDL-----VNDFYCDCKNGWKGKTC 702
Score = 34.7 bits (78), Expect = 1.5
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 2090 WTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
W + ++A S C + CHNGGTC + +G SF C C + G C ++
Sbjct: 735 WEGTTCNIARNSSCLPNPCHNGGTC----VVNG-ESFTCVCKEGWEGPICAQN 782
Score = 34.3 bits (77), Expect = 2.0
Identities = 18/60 (30%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Query: 2890 CTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
C NG C+ W G CN+++ H S +P C C GW G YC+
Sbjct: 212 CDQNGNK---TCMEGWMGPECNRAICRQGCSPKHGSCKLPGD-----CRCQYGWQGLYCD 263
Score = 33.5 bits (75), Expect = 3.4
Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Query: 2897 FSCRCLPDWAGNTCNQSVSCL--NNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+ C C +W G C++ ++ + CL+ C Y C C G+ G CE
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE 334
Score = 32.3 bits (72), Expect = 7.6
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 5/41 (12%)
Query: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
A C D CHN G+C L F+C+C +TG C
Sbjct: 336 AEHACLSDPCHNRGSCKETSL-----GFECECSPGWTGPTC 371
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 377 bits (967), Expect = e-103
Identities = 221/752 (29%), Positives = 315/752 (41%), Gaps = 98/752 (13%)
Query: 521 NSSC---WFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQH 577
N +C W E + +C GC+ L + C W G +EC
Sbjct: 228 NKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC---------DECVP 278
Query: 578 EAVCKDE--INRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALS---HNCNCSGL 632
C + +C+C ++ G LC +++YC +H + G C+ + C C
Sbjct: 279 YPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCP-- 336
Query: 633 QRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKN 692
Y CE C S C NG + + F C G+ G C +DIDECAS+PC
Sbjct: 337 DGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAA 396
Query: 693 GATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLH 752
G TC+DQ VDGF C+C +VG C+ D++DC C+H TCKDL
Sbjct: 397 GGTCVDQ--------------VDGFECICPEQWVGATCQLDVNDC-RGQCQHGGTCKDLV 441
Query: 753 LSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINE 812
YQCVC + G CE E +EC +PC + C DL + C C G++G C +++
Sbjct: 442 NGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDL 501
Query: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD------------------ 854
C+ PC NG C+ + G + C CP + G+ C C
Sbjct: 502 CEPSPCRNGARCYN--LEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGM 559
Query: 855 ---LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNN 911
C + C++ N CIC F G C ++ DCL C++ G C D V+
Sbjct: 560 PGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDA 619
Query: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK 971
FRC C G+ G LC+ N+C +PC + G C DL N F+C C+ + G C +C
Sbjct: 620 FRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCD 679
Query: 972 ISPCLDEENCVYRTDGYNCLCAPGYTGINCEI-NLDECLSEPCLHDGVCIDGINHYTCDC 1030
C + C D + C C PG+ G C + CL PC++ G C+ ++C C
Sbjct: 680 AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC 739
Query: 1031 KSGFFGTHCETNANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTSIPCM 1089
+ G+ G C N NDC PC +G C + +N + C C C+I I++C S PC
Sbjct: 740 RDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCA 799
Query: 1090 NEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRC 1149
C +G+ C CP G G C++ I G G + R
Sbjct: 800 YGATCVDEINGYRCSCPPGRAGPRCQEVI---------------------GFGRSCWSRG 838
Query: 1150 LPGFSGQFCEININECSSSPCLHG-ADCEDHINGYVCKCQPGWSGHHCENELECIPNSC- 1207
P G + +C+S CL G DC K GW + E + C
Sbjct: 839 TPFPHGSSW---VEDCNSCRCLDGRRDCS--------KVWCGWKPCLLAGQPEALSAQCP 887
Query: 1208 VHELCMENEPGSTCLCTPGFMTCSIGLLCGDE 1239
+ + C+E PG CL P C CG E
Sbjct: 888 LGQRCLEKAPGQ-CLRPP----CEAWGECGAE 914
Score = 322 bits (826), Expect = 3e-87
Identities = 193/643 (30%), Positives = 274/643 (42%), Gaps = 106/643 (16%)
Query: 388 CEKDYPCSCISGFTEKNCEKAI--DHCKLLSINCLNEEWC---FNIIGRFKYVCIP--GC 440
C++ +C+ G+ K C++A+ C LL C C + GRF C+P GC
Sbjct: 223 CDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGC 282
Query: 441 TKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAY 500
C + C C + G+ DK L + GS
Sbjct: 283 VHGSC--------VEPWQCNCETNWGGLLCDK---------DLNYCGSHHP--------- 316
Query: 501 FFLAANCTEDATYVN-DPEDNNSSCWFPHEG----------TKEICANGCSCLSEEDSQE 549
CT T +N +P+ +C + G T CANG SC E
Sbjct: 317 ------CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC--HEVPSG 368
Query: 550 YRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCL 609
+ C W+G + + N C C D+++ C C ++G C ++V+ C
Sbjct: 369 FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCR 428
Query: 610 GNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKC 669
G G C L + C + + CE++ ++C S+ C +G L F C
Sbjct: 429 GQCQHG--GTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHC 486
Query: 670 VPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPF-----------------K 712
GF G CE+D+D C PC+NGA C + G+Y+C C F +
Sbjct: 487 PQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACR 546
Query: 713 VVDG-------------------------------FSCLCNPGYVGIRCEQDIDDCILNA 741
V+DG FSC+C+ G+ G C ++IDDC+
Sbjct: 547 VIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP 606
Query: 742 CEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGW 801
C + TC D +++C C S WEG C+ N+C +PC + C DL + C C GW
Sbjct: 607 CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 666
Query: 802 TGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCR 861
G+ C +CD+ C NGG C++S F C CPP + G C N L NPC
Sbjct: 667 KGKTCHSREFQCDAYTCSNGGTCYDS--GDTFRCACPPGWKGSTCAVAKN-SSCLPNPCV 723
Query: 862 NNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFS 921
N TC+ A+ CICR+ +EG+ C + DC L C + G C D VN FRC C PGF+
Sbjct: 724 NGGTCVG-SGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFA 782
Query: 922 GSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE 964
G C I I+EC S PC TCVD N + C+C P GP C+
Sbjct: 783 GPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 825
Score = 266 bits (679), Expect = 3e-70
Identities = 152/504 (30%), Positives = 226/504 (44%), Gaps = 61/504 (12%)
Query: 788 DLYKSYRCE------CTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLY 841
D + Y C+ C GW G+ C E + C + G C T+PG+ C C +
Sbjct: 216 DFFGHYTCDQYGNKACMDGWMGKECKEAV--CKQGCNLLHGGC---TVPGE--CRCSYGW 268
Query: 842 TGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC-LFLSCQ 900
G+FC + +H C V+ Q C C + G C+ D+ C C
Sbjct: 269 QGRFCDECVPYPGCVHGSC---------VEPWQ-CNCETNWGGLLCDKDLNYCGSHHPCT 318
Query: 901 DYGDCEDMV-NNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYH 959
+ G C + + +RC C G+SG CE + C+S PC N G+C ++ + F C+C +
Sbjct: 319 NGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 960 GPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVC 1019
GP C LD+++C +PC CV + DG+ C+C + G C++++++C + C H G C
Sbjct: 379 GPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGGTC 437
Query: 1020 IDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKI 1078
D +N Y C C GF G HCE ++C S+PC G C +L + + C C + C++
Sbjct: 438 KDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV 497
Query: 1079 KINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCE-----------KSIDNC---AEP 1124
++ C PC N C + C CP + G C + ID C A P
Sbjct: 498 DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGP 557
Query: 1125 ELN----SVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHI 1180
+ S +C G CV PG F C C GF+G +C NI++C PC +G C D +
Sbjct: 558 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEV 617
Query: 1181 NGYVCKCQPGWSGHHCE-NELECIPNSC-VHELCMENEPGSTCLCTPGF----------- 1227
+ + C C GW G C+ N +C+P+ C C + C C G+
Sbjct: 618 DAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ 677
Query: 1228 ---MTCSIGLLCGDEIRRITCLTP 1248
TCS G C D C P
Sbjct: 678 CDAYTCSNGGTCYDSGDTFRCACP 701
Score = 231 bits (588), Expect = 1e-59
Identities = 181/747 (24%), Positives = 276/747 (36%), Gaps = 116/747 (15%)
Query: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC-SFKPCKNNGSCI 229
+FC E + C HG C+ E W C+C+ + G C ++L+ C S PC N G+CI
Sbjct: 271 RFCDECVPYPGCV-HGSCV-EPWQ----CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCI 324
Query: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
N + Y C C ++G+NC + C + C +G + + F C C +SGP
Sbjct: 325 NA----EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGP 380
Query: 290 FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK 349
C + C S G C + + CP+ + DV++ CQ+G C
Sbjct: 381 TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCR-GQCQHGGTCKD 439
Query: 350 ISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI 409
+ N C+C F C+ + C S P + C+ + C C GF+ CE +
Sbjct: 440 LVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDV 499
Query: 410 DHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGIC 469
D C+ C N C+N+ G + C C F G
Sbjct: 500 DLCE--PSPCRNGARCYNLEG-------------------------DYYCACPDDFGG-- 530
Query: 470 QDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHE 529
+ C + C A V D +++ P
Sbjct: 531 ---------------------KNCSVPREP-------CPGGACRVIDGCGSDAGPGMPGT 562
Query: 530 GTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR 589
+C C+S+ + +C + G EN D C++ C DE++ R
Sbjct: 563 AASGVCGPHGRCVSQPGGN-FSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFR 621
Query: 590 CSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKS 649
C C + G LC N + CL + S G C L ++ C+ ++ C C +
Sbjct: 622 CFCPSGWEGELCDTNPNDCLPDPCHS-RGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA 680
Query: 650 ASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDE-CASHPCKNGATCIDQPGNYFCQCV 708
+C NG T F C PG+KG+ C + + C +PC NG TC+ +
Sbjct: 681 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGAS------ 734
Query: 709 PPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFC 768
FSC+C G+ G C + +DC C + C D ++C C + G C
Sbjct: 735 --------FSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDC 786
Query: 769 EQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEI------------------ 810
+EC+ +PC +TC D YRC C G G C E I
Sbjct: 787 RINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSS 846
Query: 811 --NECDSDPCMNGGL-CHE-------STIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPC 860
+C+S C++G C + + GQ L GQ C ++ L PC
Sbjct: 847 WVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAP-GQCLRPPC 905
Query: 861 RNNSTCLALVDANQHCICREEFEGKNC 887
C A + C+ R NC
Sbjct: 906 EAWGECGAEEPPSTPCLPRSGHLDNNC 932
Score = 73.2 bits (178), Expect = 4e-12
Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC--NQSVSCLNNLCLHQSLCIPDQSFSYS 2936
C TC NGG C +G TF C C P W G+TC ++ SCL N C++ C+ S+S
Sbjct: 678 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV-GSGASFS 736
Query: 2937 CLCTLGWVGRYCENKTS 2953
C+C GW GR C + T+
Sbjct: 737 CICRDGWEGRTCTHNTN 753
Score = 63.2 bits (152), Expect = 4e-09
Identities = 42/116 (36%), Positives = 48/116 (41%), Gaps = 11/116 (9%)
Query: 2306 RGCILDLQVNNKEFFIIDEARHGKNIENCHVP--WCAHHLCRNNGTCISDNENLFCECPR 2363
RG DL N + D+ GK CH C + C N GTC + C CP
Sbjct: 648 RGRCYDLV--NDFYCACDDGWKGKT---CHSREFQCDAYTCSNGGTCYDSGDTFRCACPP 702
Query: 2364 LYSGKLCQFA---SCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
+ G C A SC NPC NG TCV SG C+C G G CT N P
Sbjct: 703 GWKGSTCAVAKNSSCLPNPCVNGGTCV-GSGASFSCICRDGWEGRTCTHNTNDCNP 757
Score = 63.2 bits (152), Expect = 4e-09
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 33/114 (28%)
Query: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP----------------- 2654
S C C NGGTC+ SG S C C GW+G CT + C+P
Sbjct: 715 SSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFR 774
Query: 2655 ----------------EHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQAL 2692
+ C+ GATC+ +GY C CP G G C++ +
Sbjct: 775 CECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 828
Score = 62.4 bits (150), Expect = 7e-09
Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 2609 CHASP--CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETV-STCDPEHDPPHHCSRG 2665
CH+ C C NGGTC +SG + C C GWKGS C S+C P+ C G
Sbjct: 671 CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC-----LPNPCVNG 725
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
TC+ ++C C G G C + +P
Sbjct: 726 GTCVGSGASFSCICRDGWEGRTCTHNTNDCNP 757
Score = 62.0 bits (149), Expect = 9e-09
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P + +C ++PC+ GGTC++ C C W G+ C V+ C +
Sbjct: 380 PTCALDIDECASNPCAA-----GGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ---- 430
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C G TC L +GY C CP G G +CE
Sbjct: 431 --CQHGGTCKDLVNGYQCVCPRGFGGRHCE 458
Score = 60.1 bits (144), Expect = 3e-08
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 10/101 (9%)
Query: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
P+G+ +GR+ + + C+ C NGG+C E + C+C +GW G C + C
Sbjct: 336 PDGY--SGRNCEKAEHA-CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDEC--- 389
Query: 2656 HDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISD 2696
+ C+ G TC+ G+ C CP G C+ L ++D
Sbjct: 390 --ASNPCAAGGTCVDQVDGFECICPEQWVGATCQ--LDVND 426
Score = 59.3 bits (142), Expect = 6e-08
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYS 2936
AC N C NGG C + F C C W+G TC + C +N C C+ DQ +
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCV-DQVDGFE 408
Query: 2937 CLCTLGWVGRYCE 2949
C+C WVG C+
Sbjct: 409 CICPEQWVGATCQ 421
Score = 56.2 bits (134), Expect = 5e-07
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL-CLHQSL 2926
GS ++C N C NGG C +G +FSC C W G TC + + N L C + +
Sbjct: 706 GSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGI 765
Query: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
C+ ++ + C C G+ G C
Sbjct: 766 CVDGVNW-FRCECAPGFAGPDC 786
Score = 55.8 bits (133), Expect = 6e-07
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCL 2938
C N C GG C F C C W G TC V+ C H C D Y C+
Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTC-KDLVNGYQCV 447
Query: 2939 CTLGWVGRYCE 2949
C G+ GR+CE
Sbjct: 448 CPRGFGGRHCE 458
Score = 55.1 bits (131), Expect = 1e-06
Identities = 36/106 (33%), Positives = 49/106 (46%), Gaps = 11/106 (10%)
Query: 2589 HFRGLGNPEGH----PNAGRSVGQCHAS--PCSLMKCGNGGTCIESGTSVYCNCTTGWKG 2642
H R + P G+ ++G + CH + C C NGGTCI+ + C C +GW+G
Sbjct: 571 HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 630
Query: 2643 SFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYC 2688
C + C P DP H SRG C L + + C C G G C
Sbjct: 631 ELCDTNPNDCLP--DPCH--SRG-RCYDLVNDFYCACDDGWKGKTC 671
Score = 55.1 bits (131), Expect = 1e-06
Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 2344 CRNNGTCISDNENLF-CECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVCLCPY 2400
C N G C+ D N F CEC ++G C+ C+++PC GATCV + C CP
Sbjct: 760 CYNGGICV-DGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEIN-GYRCSCPP 817
Query: 2401 GRSGPLCTDAINITQPRFSGTDAFGYTS 2428
GR+GP C + I + +S F + S
Sbjct: 818 GRAGPRCQEVIGFGRSCWSRGTPFPHGS 845
Score = 54.7 bits (130), Expect = 1e-06
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 8/70 (11%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL-PHGYTCFCPL 2681
G+C+E CNC T W G C + ++ C H C+ G TCI+ P Y C CP
Sbjct: 285 GSCVEPWQ---CNCETNWGGLLCDKDLNYCGSHHP----CTNGGTCINAEPDQYRCTCPD 337
Query: 2682 GTTGIYCEQA 2691
G +G CE+A
Sbjct: 338 GYSGRNCEKA 347
Score = 53.9 bits (128), Expect = 2e-06
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
CA C + G C + C CP+ +SG LC+ CE +PC NGA C G D C
Sbjct: 464 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG-DYYC 522
Query: 2397 LCPYGRSGPLCT 2408
CP G C+
Sbjct: 523 ACPDDFGGKNCS 534
Score = 53.5 bits (127), Expect = 3e-06
Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 7/89 (7%)
Query: 2609 CHASP--CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGA 2666
C +P C C + G C + YC C GWKG C CD + CS G
Sbjct: 633 CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCD-----AYTCSNGG 687
Query: 2667 TCISLPHGYTCFCPLGTTGIYCEQALSIS 2695
TC + C CP G G C A + S
Sbjct: 688 TCYDSGDTFRCACPPGWKGSTCAVAKNSS 716
Score = 53.1 bits (126), Expect = 4e-06
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C++ GTC C CPR + G+ C+ C ++PC +G C + C CP G
Sbjct: 431 CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLAD-GFHCHCPQG 489
Query: 2402 RSGPLCTDAINITQP 2416
SGPLC +++ +P
Sbjct: 490 FSGPLCEVDVDLCEP 504
Score = 52.4 bits (124), Expect = 7e-06
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 2619 CGNGGTCI-ESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
CG G C+ + G + C C +G+ G++C E + C + C G TCI + C
Sbjct: 568 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP-----CRNGGTCIDEVDAFRC 622
Query: 2678 FCPLGTTGIYCE 2689
FCP G G C+
Sbjct: 623 FCPSGWEGELCD 634
Score = 52.0 bits (123), Expect = 9e-06
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C+ C +GG C + +C+C G+ G C V C+P C GA C +L
Sbjct: 464 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPS-----PCRNGARCYNLEG 518
Query: 2674 GYTCFCPLGTTGIYC 2688
Y C CP G C
Sbjct: 519 DYYCACPDDFGGKNC 533
Score = 51.2 bits (121), Expect = 2e-05
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
N+ DC G CRNGG C F C C W G C+ + + CL + C + C
Sbjct: 598 NIDDCLG-----QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCY 652
Query: 2929 PDQSFSYSCLCTLGWVGRYCENK 2951
D + C C GW G+ C ++
Sbjct: 653 -DLVNDFYCACDDGWKGKTCHSR 674
Score = 50.8 bits (120), Expect = 2e-05
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 2875 DGTACGYNT-------CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSL 2926
+G C +NT C NGG C F C C P +AG C ++ C ++ C + +
Sbjct: 744 EGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGAT 803
Query: 2927 CIPDQSFSYSCLCTLGWVGRYCENKTSF 2954
C+ D+ Y C C G G C+ F
Sbjct: 804 CV-DEINGYRCSCPPGRAGPRCQEVIGF 830
Score = 50.4 bits (119), Expect = 3e-05
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGAT 2385
G+N E C + C N G+C C CP +SG C C +NPC G T
Sbjct: 341 GRNCEKAEHA-CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGT 399
Query: 2386 CVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
CV + C+CP G C +N
Sbjct: 400 CVDQV-DGFECICPEQWVGATCQLDVN 425
Score = 50.1 bits (118), Expect = 4e-05
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 5/81 (6%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
+C +GGTC + C C G+ G C C C G C L G+ C
Sbjct: 430 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP-----CHSGGLCEDLADGFHC 484
Query: 2678 FCPLGTTGIYCEQALSISDPS 2698
CP G +G CE + + +PS
Sbjct: 485 HCPQGFSGPLCEVDVDLCEPS 505
Score = 46.6 bits (109), Expect = 4e-04
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 2868 GSNVGD-CDGTACGYNTCRNGGECTVN-GTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQ 2924
GS+ G GTA C G C G FSC C + G C++++ CL C +
Sbjct: 552 GSDAGPGMPGTAAS-GVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG 610
Query: 2925 SLCIPDQSFSYSCLCTLGWVGRYCE 2949
CI D+ ++ C C GW G C+
Sbjct: 611 GTCI-DEVDAFRCFCPSGWEGELCD 634
Score = 46.6 bits (109), Expect = 4e-04
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 2334 CH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPK 2389
CH + C CRN GTCI + + C CP + G+LC C +PC + C
Sbjct: 595 CHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDL 654
Query: 2390 SGTDIVCLCPYGRSGPLC 2407
D C C G G C
Sbjct: 655 V-NDFYCACDDGWKGKTC 671
Score = 43.9 bits (102), Expect = 0.003
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTD-IV 2395
C + C N GTC+ + C C + G+ C + C PC NG CV G +
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV--DGVNWFR 774
Query: 2396 CLCPYGRSGPLCTDAINITQPRFSGTDAFGYT 2427
C C G +GP C INI + + S A+G T
Sbjct: 775 CECAPGFAGPDC--RINIDECQ-SSPCAYGAT 803
Score = 41.6 bits (96), Expect = 0.013
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 2337 PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASC-ENNPCGNGATCVPKSGTD 2393
P C H G+C+ E C C + G LC C ++PC NG TC+
Sbjct: 280 PGCVH------GSCV---EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ 330
Query: 2394 IVCLCPYGRSGPLCTDA 2410
C CP G SG C A
Sbjct: 331 YRCTCPDGYSGRNCEKA 347
Score = 40.0 bits (92), Expect = 0.036
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 15/84 (17%)
Query: 2876 GTACGYNTCRNG-----GECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPD 2930
G C C+ G G CTV G CRC W G C++ V C+H S P
Sbjct: 237 GKECKEAVCKQGCNLLHGGCTVPG---ECRCSYGWQGRFCDECVPYPG--CVHGSCVEP- 290
Query: 2931 QSFSYSCLCTLGWVGRYCENKTSF 2954
+ C C W G C+ ++
Sbjct: 291 ----WQCNCETNWGGLLCDKDLNY 310
Score = 40.0 bits (92), Expect = 0.036
Identities = 27/104 (25%), Positives = 35/104 (33%), Gaps = 24/104 (23%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-----------ETVSTCDP 2654
V C SPC NG C YC C + G C+ + C
Sbjct: 499 VDLCEPSPCR-----NGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGS 553
Query: 2655 EHDP-------PHHCSRGATCISLPHG-YTCFCPLGTTGIYCEQ 2690
+ P C C+S P G ++C C G TG YC +
Sbjct: 554 DAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHE 597
Score = 39.3 bits (90), Expect = 0.062
Identities = 20/47 (42%), Positives = 23/47 (48%), Gaps = 5/47 (10%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPS 2149
C CH+GG C L+ G F C CP F+G CE D L PS
Sbjct: 464 CASSPCHSGGLCED--LADG---FHCHCPQGFSGPLCEVDVDLCEPS 505
Score = 39.3 bits (90), Expect = 0.062
Identities = 23/102 (22%), Positives = 35/102 (34%), Gaps = 25/102 (24%)
Query: 2336 VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF----------------------- 2372
V C CRN C + + +C CP + GK C
Sbjct: 499 VDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPG 558
Query: 2373 --ASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
+ + CG CV + G + C+C G +G C + I+
Sbjct: 559 MPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID 600
Score = 38.9 bits (89), Expect = 0.081
Identities = 21/100 (21%), Positives = 34/100 (34%), Gaps = 24/100 (24%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN--------------------- 2911
+ D C + CRNG C + C C D+ G C+
Sbjct: 496 EVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDA 555
Query: 2912 ---QSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
+ + +C C+ ++SC+C G+ G YC
Sbjct: 556 GPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC 595
Score = 37.7 bits (86), Expect = 0.18
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 2901 CLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
C+ W G C ++V LH +P + C C+ GW GR+C+
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGE-----CRCSYGWQGRFCD 274
Score = 37.7 bits (86), Expect = 0.18
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 2897 FSCRCLPDWAGNTCNQSVSCL--NNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSF 2954
+ C C +W G C++ ++ ++ C + CI + Y C C G+ GR CE
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Query: 2955 STAKFMGN 2962
T+ N
Sbjct: 351 CTSNPCAN 358
Score = 36.2 bits (82), Expect = 0.53
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK--DAGLFFPSFNGNSYLELP 2159
C NGGTC +++ ++C CP ++GR CEK A P NG S E+P
Sbjct: 317 CTNGGTC----INAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVP 366
Score = 35.8 bits (81), Expect = 0.69
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 11/54 (20%)
Query: 2093 VSPSVAAPSVCQQDV------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
+ P + CQ DV C +GGTC + + +QC CP F GR CE
Sbjct: 410 ICPEQWVGATCQLDVNDCRGQCQHGGTCKDL-----VNGYQCVCPRGFGGRHCE 458
Score = 35.4 bits (80), Expect = 0.90
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
A C + C NGG+CH + SG F+C CP ++G C D
Sbjct: 347 AEHACTSNPCANGGSCHEV--PSG---FECHCPSGWSGPTCALD 385
Score = 34.3 bits (77), Expect = 2.0
Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 2090 WTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLF--F 2147
W + +VA S C + C NGGTC + SG SF C C + GR C +
Sbjct: 704 WKGSTCAVAKNSSCLPNPCVNGGTC----VGSG-ASFSCICRDGWEGRTCTHNTNDCNPL 758
Query: 2148 PSFNG 2152
P +NG
Sbjct: 759 PCYNG 763
Score = 33.5 bits (75), Expect = 3.4
Identities = 19/71 (26%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C + C +GG C F C C ++G C V C + C + + C + Y C
Sbjct: 464 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCY-NLEGDYYC 522
Query: 2938 LCTLGWVGRYC 2948
C + G+ C
Sbjct: 523 ACPDDFGGKNC 533
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 337 bits (865), Expect = 8e-92
Identities = 195/626 (31%), Positives = 285/626 (45%), Gaps = 94/626 (15%)
Query: 669 CVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPF----------------- 711
C+ GF G +C +D++ECAS PC+NG TC ++ CQC F
Sbjct: 299 CLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKEC 358
Query: 712 ------KVVDGFS-CLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWE 764
+V +G + C+C GY G CE D+DDC + C + +C DL +Y C+C ++
Sbjct: 359 QHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFK 418
Query: 765 GNFCEQESNE----CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEI-NECDSDPCM 819
G CE + C PC N TC D + Y CEC G+ G +C E + ++C+ C
Sbjct: 419 GLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CR 475
Query: 820 NGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH---- 875
NGG C + +C CP + G C ++ PC N+ C +H
Sbjct: 476 NGGRCLGANTT---LCQCPLGFFGLLCE-----FEITAMPCNMNTQCPDGGYCMEHGGSY 527
Query: 876 -CICREEFEGKN-----CEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCE-IE 928
C+C + + C+ D C + G C+ +++ C C GF G CE
Sbjct: 528 LCVCHTDHNASHSLPSPCDSD-------PCFNGGSCDAHDDSYTCECPRGFHGKHCEKAR 580
Query: 929 INECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDV-NKCKISPCLDEENCVYRTDG 987
+ CSS PC+N GTC + + C+C + G CE+ + C PC + C +
Sbjct: 581 PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGK 640
Query: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDC- 1046
Y C C PG++G +CEI C PC++ G C D + C C++G+ G C+ DC
Sbjct: 641 YKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV-DCG 699
Query: 1047 ----LSNPCLHGRCTEL--INEYPCS-------------CDADGTST---QCKIKINDCT 1084
+ + L T L + Y C C G + QC ++I++C
Sbjct: 700 PPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECR 758
Query: 1085 SIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNC-AEPELNSVICLNGGICVDGPGH 1143
S PC++ G CQ G+ C+C GY GA+CE D C A P C NGG C + PG
Sbjct: 759 SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP------CRNGGSCRNLPG- 811
Query: 1144 TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE-C 1202
+ CRC GF G CE ++ C SSPC HG CE Y+C C + G+HCE + C
Sbjct: 812 AYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPC 871
Query: 1203 IPNSC-VHELCMENEPGSTCLCTPGF 1227
+ C C+ + +C C G+
Sbjct: 872 FSSPCGGRGYCLASNGSHSCTCKVGY 897
Score = 325 bits (834), Expect = 3e-88
Identities = 200/639 (31%), Positives = 275/639 (43%), Gaps = 65/639 (10%)
Query: 535 CANGCSCLSE--EDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSC 592
C NG C+ + + Y C + G + + CQ+ C IN RC C
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
Query: 593 SLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASC 652
+ G C C G C + + C Y CE+D +DC C
Sbjct: 338 PAGFGGPTCETAQSPC-DTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPC 396
Query: 653 KNGTTSTHLRGYFFRKCVPGFKGTQCEIDI----DECASHPCKNGATCIDQPGNYFCQCV 708
NG + L G + C FKG +CE D C S PC NG TC+D Y C+C
Sbjct: 397 LNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP 456
Query: 709 PPFKVVD-------------GFSCL--------CNPGYVGIRCEQDID--DCILNA-CEH 744
F +D G CL C G+ G+ CE +I C +N C
Sbjct: 457 EGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPD 516
Query: 745 NSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQ 804
C + SY CVC +D N + C +PC N +C SY CEC G+ G+
Sbjct: 517 GGYCMEHGGSYLCVCHTDH--NASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGK 574
Query: 805 NCSE-EINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCH-QRYNLCDLLHNPCRN 862
+C + + C S PC NGG C E+ G++ C CP +TG+ C + + C PC N
Sbjct: 575 HCEKARPHLCSSGPCRNGGTCKEAG--GEYHCSCPYRFTGRHCEIGKPDSC--ASGPCHN 630
Query: 863 NSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG 922
TC + C C F G++CEI C C + G CED +F C C+ G+ G
Sbjct: 631 GGTCFHYI-GKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
Query: 923 SLCEIEINECSSEPCKN-----NGTCVDLTNRFFCN-------------CEPEYHGPFCE 964
C+ E++ E K+ NGT + + C+ C+P HG + E
Sbjct: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP--HGVWSE 747
Query: 965 ----LDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCI 1020
L++++C+ PCL +C R GY CLC+ GY G +CE+ DEC + PC + G C
Sbjct: 748 PPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCR 807
Query: 1021 DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIK 1079
+ Y C C +GF G HCET + C S+PC HG RC Y C C C+
Sbjct: 808 NLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETV 867
Query: 1080 INDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
+ C S PC G+C S +C C GYTG C K +
Sbjct: 868 SDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 303 bits (777), Expect = 1e-81
Identities = 187/584 (32%), Positives = 261/584 (44%), Gaps = 56/584 (9%)
Query: 686 ASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHN 745
A PC NG CID C P ++C C G+ G RC D+++C C++
Sbjct: 274 ALRPCLNGGKCIDD-----CVTGNP-----SYTCSCLSGFTGRRCHLDVNECASQPCQNG 323
Query: 746 STCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQN 805
TC S++C C + + G CE + C C++ C S C C +G+TG
Sbjct: 324 GTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAA 383
Query: 806 CSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFC----HQRYNLCDLLHNPCR 861
C ++++C DPC+NGG C + + G + CLC + G C H + C L PC
Sbjct: 384 CEMDVDDCSPDPCLNGGSCVD--LVGNYTCLCAEPFKGLRCETGDHPVPDAC--LSAPCH 439
Query: 862 NNSTCLALVDANQH--CICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPG 919
N TC VDA+Q C C E F G +C V D C++ G C N C C G
Sbjct: 440 NGGTC---VDADQGYVCECPEGFMGLDCRERVPD--DCECRNGGRCLG-ANTTLCQCPLG 493
Query: 920 FSGSLCEIEIN--ECS-SEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCL 976
F G LCE EI C+ + C + G C++ + C C +++ + C PC
Sbjct: 494 FFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSL--PSPCDSDPCF 551
Query: 977 DEENCVYRTDGYNCLCAPGYTGINCE-INLDECLSEPCLHDGVCIDGINHYTCDCKSGFF 1035
+ +C D Y C C G+ G +CE C S PC + G C + Y C C F
Sbjct: 552 NGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFT 611
Query: 1036 GTHCETNAND-CLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGF 1093
G HCE D C S PC + G C I +Y C C + C+I + C PC+N G
Sbjct: 612 GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT 671
Query: 1094 CQKSAHGFTCICPRGYTGAYCEKSIDNCAEPE--LNSVICLNG-------------GICV 1138
C+ F C C GY G C+ +D C PE ++ + NG G +
Sbjct: 672 CEDRDTDFFCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYSL 730
Query: 1139 DGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCEN 1198
P C+ +S + I+EC S PCLHG C+D + GY+C C G+ G HCE
Sbjct: 731 SAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL 790
Query: 1199 EL-ECIPNSCVHELCMENEPGS-TCLCTPGFMTCSIGLLCGDEI 1240
E EC + C + N PG+ C C GF +G+ C E+
Sbjct: 791 ERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEV 830
Score = 248 bits (634), Expect = 5e-65
Identities = 147/453 (32%), Positives = 199/453 (43%), Gaps = 63/453 (13%)
Query: 846 CHQRYNLCDLLHNPCRNNSTCL---ALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDY 902
C ++C L PC N C+ + + C C F G+ C +DV +C CQ+
Sbjct: 265 CGHTTSVC-LALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNG 323
Query: 903 GDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPF 962
G C +N+FRC C GF G CE + C ++ C++ G C C C+ Y G
Sbjct: 324 GTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAA 383
Query: 963 CELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEIN----LDECLSEPCLHDGV 1018
CE+DV+ C PCL+ +CV Y CLCA + G+ CE D CLS PC + G
Sbjct: 384 CEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT 443
Query: 1019 CIDGINHYTCDCKSGFFGTHCE---------TNANDCL---------------------- 1047
C+D Y C+C GF G C N CL
Sbjct: 444 CVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEI 503
Query: 1048 -SNPCL-------HGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAH 1099
+ PC G C E Y C C D ++ + C S PC N G C
Sbjct: 504 TAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS--LPSPCDSDPCFNGGSCDAHDD 561
Query: 1100 GFTCICPRGYTGAYCEKSIDNCAEPEL-NSVICLNGGICVDGPGHTFDCRCLPGFSGQFC 1158
+TC CPRG+ G +CEK A P L +S C NGG C + G + C C F+G+ C
Sbjct: 562 SYTCECPRGFHGKHCEK-----ARPHLCSSGPCRNGGTCKEAGGE-YHCSCPYRFTGRHC 615
Query: 1159 EI-NINECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE-NELECIPNSCVH-ELCMEN 1215
EI + C+S PC +G C +I Y C C PG+SG HCE C + CV+ C +
Sbjct: 616 EIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDR 675
Query: 1216 EPGSTCLCTPGFM--TCSIGLLCG--DEIRRIT 1244
+ C C G+M C + CG +E++ T
Sbjct: 676 DTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHAT 708
Score = 239 bits (610), Expect = 3e-62
Identities = 156/597 (26%), Positives = 232/597 (38%), Gaps = 92/597 (15%)
Query: 528 HEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINR 587
+E + C NG +C +S +R C + G + ECQH C+ E
Sbjct: 313 NECASQPCQNGGTCTHGINS--FRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGS 370
Query: 588 PRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDT--- 644
C C Y G C ++VD C + ++ G C+ L N C + ++ CE
Sbjct: 371 AVCVCQAGYTGAACEMDVDDCSPDPCLN-GGSCVDLVGNYTCLCAEPFKGLRCETGDHPV 429
Query: 645 -EDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDI-DECASH-------------- 688
+ C SA C NG T + +C GF G C + D+C
Sbjct: 430 PDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ 489
Query: 689 -----------------------PCKNGATCIDQPGNYFCQCVPPFKVV----------- 714
C +G C++ G+Y C C
Sbjct: 490 CPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDP 549
Query: 715 -----------DGFSCLCNPGYVGIRCEQDIDD-CILNACEHNSTCKDLHLSYQCVCLSD 762
D ++C C G+ G CE+ C C + TCK+ Y C C
Sbjct: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609
Query: 763 WEGNFCE-QESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNG 821
+ G CE + + C PC N TC Y+C+C G++G++C + C PC+NG
Sbjct: 610 FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNG 669
Query: 822 GLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC---DLLHNPCRNNSTCLALVDANQHC-- 876
G C + F C C Y G+ C + ++ H R N T L V A C
Sbjct: 670 GTCEDRDT--DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAV-ALYACDR 726
Query: 877 -----------ICREE---FEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG 922
+C+ E C +++ +C C G C+D V + C+C G+ G
Sbjct: 727 GYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG 785
Query: 923 SLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCV 982
+ CE+E +EC + PC+N G+C +L + C C + G CE +V+ C SPC C
Sbjct: 786 AHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCE 845
Query: 983 YRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 1039
Y C+C + G +CE D C S PC G C+ ++C CK G+ G C
Sbjct: 846 SGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 234 bits (596), Expect = 1e-60
Identities = 183/675 (27%), Positives = 269/675 (39%), Gaps = 92/675 (13%)
Query: 218 SFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNS 277
+ +PC N G CI+ + +Y C C FTG+ C + +C C +G NS
Sbjct: 274 ALRPCLNGGKCIDDCVTGNP-SYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINS 332
Query: 278 FICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS 337
F C+C F GP CE + PC + G C + + C G + E DV + S
Sbjct: 333 FRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCS 392
Query: 338 LVPCQNGTDCIKISNDVMCICSPIFTDLLCKS----IQTSCESFPLRNNATCKKCEKDYP 393
PC NG C+ + + C+C+ F L C++ + +C S P N TC ++ Y
Sbjct: 393 PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYV 452
Query: 394 CSCISGFTEKNC-EKAIDHCKLLS-INCL--NEEWCFNIIGRFKYVCIPGCTKNPCWFLK 449
C C GF +C E+ D C+ + CL N C +G F +C T PC
Sbjct: 453 CECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPC---- 508
Query: 450 NVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTE 509
+ C D G Y + G GS C +A L + C
Sbjct: 509 --------------NMNTQCPDGG-----YCMEHG--GSYLCVCHTDHNASHSLPSPCDS 547
Query: 510 DATYVN---DPEDNNSSCWF-------------PHEGTKEICANGCSCLSEEDSQEYRYL 553
D + D D++ +C PH + C NG +C +E EY
Sbjct: 548 DPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTC--KEAGGEYHCS 605
Query: 554 CFLRWAGNMYLENTTDD-QENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNH 612
C R+ G D C + C I + +C C + GR C + C +
Sbjct: 606 CPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP 665
Query: 613 SISVHGLCLALSHN--CNCSGLQRYERNICEID---TEDCKSASCK-NGTTSTHL----- 661
++ G C + C+C R E+D E+ K A+ + NGT +
Sbjct: 666 CVN-GGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
Query: 662 -RGYF------FRKCVP---GFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPF 711
RGY R C P + QC ++IDEC S PC +G +C D+ Y C
Sbjct: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYLC------ 777
Query: 712 KVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQE 771
LC+ GY G CE + D+C + C + +C++L +Y C C + + G CE E
Sbjct: 778 --------LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETE 829
Query: 772 SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPG 831
+ C +PC++ C +Y C C + G +C + C S PC G C S G
Sbjct: 830 VDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASN--G 887
Query: 832 QFVCLCPPLYTGQFC 846
C C YTG+ C
Sbjct: 888 SHSCTCKVGYTGEDC 902
Score = 168 bits (426), Expect = 7e-41
Identities = 150/646 (23%), Positives = 222/646 (34%), Gaps = 139/646 (21%)
Query: 175 QESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRE 233
Q ++ C G+C E S C CQ ++G C+ ++D CS PC N GSC++
Sbjct: 350 QSPCDTKECQHGGQCQVENGSAV--CVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVG 407
Query: 234 NWDEQAYECVCHPPFTGKNCS----EIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
N Y C+C PF G C + C C +G ++CEC E F G
Sbjct: 408 N-----YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGL 462
Query: 290 FC-------------------------------------EVSAKPC-VSLLFWKRGICPN 311
C E++A PC ++ G C
Sbjct: 463 DCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCME 522
Query: 312 SSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQ 371
+Y C ++ + + PC NG C + C C F C+ +
Sbjct: 523 HGGSYLCVCHTDHNASHSLPSPCDSD--PCFNGGSCDAHDDSYTCECPRGFHGKHCEKAR 580
Query: 372 TS-CESFPLRNNATCKKCEKDYPCSCISGFTEKNCE-KAIDHCKLLSINCLNEEWCFNII 429
C S P RN TCK+ +Y CSC FT ++CE D C S C N CF+ I
Sbjct: 581 PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC--ASGPCHNGGTCFHYI 638
Query: 430 GRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSE 489
G++K C PG + C + + C G G C+D+ F + AG
Sbjct: 639 GKYKCDCPPGFSGRHCEIAPSP--CFRSPCVNG----GTCEDRDTDFFCHCQ----AGYM 688
Query: 490 GEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK--EICANGCSCLSEEDS 547
G +CQ +D P + GT+ + C +
Sbjct: 689 GRRCQAEVDC----------------GPPEEVKHATLRFNGTRLGAVALYACDRGYSLSA 732
Query: 548 QEYRYLCFLR--WAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNV 605
+C W+ + + C H C+D + C CS Y G C +
Sbjct: 733 PSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER 792
Query: 606 DYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYF 665
D +C++ C+NG + +L G +
Sbjct: 793 D---------------------------------------ECRAHPCRNGGSCRNLPGAY 813
Query: 666 FRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGY 725
+C GF G CE ++D C S PC++G C G Y C+C +
Sbjct: 814 VCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL--------------CVCPESF 859
Query: 726 VGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQE 771
G CE D C + C C + S+ C C + G C +E
Sbjct: 860 FGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
Score = 98.6 bits (244), Expect = 9e-20
Identities = 70/288 (24%), Positives = 104/288 (36%), Gaps = 56/288 (19%)
Query: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFK-PCKNNGSCINKREN 234
+S +S C G C + Y C C P FSG++C+ + F+ PC N G+C ++ +
Sbjct: 621 DSCASGPCHNGGTCFH--YIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTD 678
Query: 235 WD---EQAY-------ECVCHPP---------FTGKNCSEI----------------IGQ 259
+ + Y E C PP F G + I
Sbjct: 679 FFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRV 738
Query: 260 CQPH------------------VCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
CQPH C HG ++C C + G CE+ C +
Sbjct: 739 CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 798
Query: 302 LFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI 361
G C N AY CP G + ET+V PCQ+G C +C+C
Sbjct: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 858
Query: 362 FTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI 409
F C+++ C S P C + C+C G+T ++C K +
Sbjct: 859 FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 63.9 bits (154), Expect = 2e-09
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 10/93 (10%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
+ +C + PC +GG+C + C C+TG++G+ C C H C G
Sbjct: 754 IDECRSQPCL-----HGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA-----HPCRNG 803
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
+C +LP Y C CP G G++CE + D S
Sbjct: 804 GSCRNLPGAYVCRCPAGFVGVHCETEVDACDSS 836
Score = 62.8 bits (151), Expect = 5e-09
Identities = 32/84 (38%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 2327 HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA---SCENNPCGNG 2383
HGK+ E C+ CRN GTC C CP ++G+ C+ SC + PC NG
Sbjct: 572 HGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNG 631
Query: 2384 ATCVPKSGTDIVCLCPYGRSGPLC 2407
TC G C CP G SG C
Sbjct: 632 GTCFHYIG-KYKCDCPPGFSGRHC 654
Score = 61.2 bits (147), Expect = 2e-08
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 7/79 (8%)
Query: 2612 SPCSLMKCGNGGTC-IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
SPC +C +GG C +E+G++V C C G+ G+ C V C P DP C G +C+
Sbjct: 351 SPCDTKECQHGGQCQVENGSAV-CVCQAGYTGAACEMDVDDCSP--DP---CLNGGSCVD 404
Query: 2671 LPHGYTCFCPLGTTGIYCE 2689
L YTC C G+ CE
Sbjct: 405 LVGNYTCLCAEPFKGLRCE 423
Score = 59.7 bits (143), Expect = 4e-08
Identities = 28/72 (38%), Positives = 40/72 (55%), Gaps = 4/72 (5%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS---CENNPCGNGATCVPKSGTDIV 2395
C C N G+C + +++ CECPR + GK C+ A C + PC NG TC ++G +
Sbjct: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTC-KEAGGEYH 603
Query: 2396 CLCPYGRSGPLC 2407
C CPY +G C
Sbjct: 604 CSCPYRFTGRHC 615
Score = 58.2 bits (139), Expect = 1e-07
Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 11/93 (11%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVC 2396
CA C N GTC C+CP +SG+ C+ A C +PC NG TC + TD C
Sbjct: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRD-TDFFC 681
Query: 2397 LCPYGRSGPLCTDAINITQP--------RFSGT 2421
C G G C ++ P RF+GT
Sbjct: 682 HCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGT 714
Score = 57.4 bits (137), Expect = 2e-07
Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
CS C NGGTC E+G +C+C + G C P+ C G TC
Sbjct: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHC----EIGKPDSCASGPCHNGGTCFHYIG 639
Query: 2674 GYTCFCPLGTTGIYCEQALSISDPSFRS 2701
Y C CP G +G +CE A S P FRS
Sbjct: 640 KYKCDCPPGFSGRHCEIAPS---PCFRS 664
Score = 55.8 bits (133), Expect = 6e-07
Identities = 34/120 (28%), Positives = 49/120 (40%), Gaps = 8/120 (6%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYE 241
C G C + + Y C C F G +C+ E+DAC PC++ G C + AY
Sbjct: 800 CRNGGSCRNLPGA--YVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES-----GGGAYL 852
Query: 242 CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
CVC F G +C + C C ++ S C C ++G C P +L
Sbjct: 853 CVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTAL 912
Score = 55.5 bits (132), Expect = 8e-07
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 2334 CH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPK 2389
CH V CA C+N GTC + C+CP + G C+ A C+ C +G C +
Sbjct: 308 CHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVE 367
Query: 2390 SGTDIVCLCPYGRSGPLCTDAINITQP 2416
+G+ VC+C G +G C ++ P
Sbjct: 368 NGS-AVCVCQAGYTGAACEMDVDDCSP 393
Score = 55.1 bits (131), Expect = 1e-06
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 7/92 (7%)
Query: 2608 QCH--ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
+CH + C+ C NGGTC S C C G+ G C S CD + C G
Sbjct: 307 RCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK-----ECQHG 361
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
C C C G TG CE + P
Sbjct: 362 GQCQVENGSAVCVCQAGYTGAACEMDVDDCSP 393
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 2611 ASPCSL-MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCI 2669
A PC++ +C +GG C+E G S C C T S + DP C G +C
Sbjct: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDP-------CFNGGSCD 557
Query: 2670 SLPHGYTCFCPLGTTGIYCEQA 2691
+ YTC CP G G +CE+A
Sbjct: 558 AHDDSYTCECPRGFHGKHCEKA 579
Score = 53.1 bits (126), Expect = 4e-06
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
CS C NGG+C++ + C C +KG C ET P+ C G TC+
Sbjct: 391 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC-ETGDHPVPDACLSAPCHNGGTCVDADQ 449
Query: 2674 GYTCFCPLGTTGIYCEQ 2690
GY C CP G G+ C +
Sbjct: 450 GYVCECPEGFMGLDCRE 466
Score = 52.4 bits (124), Expect = 7e-06
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 14/83 (16%)
Query: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS-----RGA 2666
SPC C NGG+C S C C G+ G C E PH CS G
Sbjct: 543 SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC---------EKARPHLCSSGPCRNGG 593
Query: 2667 TCISLPHGYTCFCPLGTTGIYCE 2689
TC Y C CP TG +CE
Sbjct: 594 TCKEAGGEYHCSCPYRFTGRHCE 616
Score = 52.0 bits (123), Expect = 9e-06
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLC 2398
C C N GTC+ ++ CECP + G C+ ++ C NG C+ + T +C C
Sbjct: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTT--LCQC 490
Query: 2399 PYGRSGPLC 2407
P G G LC
Sbjct: 491 PLGFFGLLC 499
Score = 50.8 bits (120), Expect = 2e-05
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSF 2933
D C C+NGG CT +F C+C + G TC + S C C H C +
Sbjct: 311 DVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENG- 369
Query: 2934 SYSCLCTLGWVGRYCE 2949
S C+C G+ G CE
Sbjct: 370 SAVCVCQAGYTGAACE 385
Score = 50.1 bits (118), Expect = 4e-05
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 2606 VGQCH--ASPC-SLMKCGNGGTCIES----GTSVYCNCTTGWKGSFCTETVSTCDPEHDP 2658
VG C S C +L C NGG CI+ S C+C +G+ G C V+ C +
Sbjct: 262 VGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQ--- 318
Query: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISD 2696
C G TC + + C CP G G CE A S D
Sbjct: 319 --PCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCD 354
Score = 50.1 bits (118), Expect = 4e-05
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 10/77 (12%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETV-STCDPEHDPPHHCSRGATCISLP 2672
C C NGGTC+++ C C G+ G C E V C+ C G C+
Sbjct: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE--------CRNGGRCLG-A 483
Query: 2673 HGYTCFCPLGTTGIYCE 2689
+ C CPLG G+ CE
Sbjct: 484 NTTLCQCPLGFFGLLCE 500
Score = 48.9 bits (115), Expect = 8e-05
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 7/73 (9%)
Query: 2344 CRNNGTCISD----NENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVCL 2397
C N G CI D N + C C ++G+ C C + PC NG TC C
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCT-HGINSFRCQ 336
Query: 2398 CPYGRSGPLCTDA 2410
CP G GP C A
Sbjct: 337 CPAGFGGPTCETA 349
Score = 48.1 bits (113), Expect = 1e-04
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
C H CRN G+C + C CP + G C + +C+++PC +G C G +C
Sbjct: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC-ESGGGAYLC 853
Query: 2397 LCPYGRSGPLCTDAINITQPRFS 2419
+CP G C ++ P FS
Sbjct: 854 VCPESFFGYHCE---TVSDPCFS 873
Score = 47.8 bits (112), Expect = 2e-04
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYS 2936
+C C NGG C + C C P ++G C + S C + C++ C D+ +
Sbjct: 622 SCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTC-EDRDTDFF 680
Query: 2937 CLCTLGWVGRYCE 2949
C C G++GR C+
Sbjct: 681 CHCQAGYMGRRCQ 693
Score = 47.0 bits (110), Expect = 3e-04
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 2313 QVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF 2372
QV N + +A + V C+ C N G+C+ N C C + G C+
Sbjct: 365 QVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCET 424
Query: 2373 A------SCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAI 2411
+C + PC NG TCV + VC CP G G C + +
Sbjct: 425 GDHPVPDACLSAPCHNGGTCV-DADQGYVCECPEGFMGLDCRERV 468
Score = 46.6 bits (109), Expect = 4e-04
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-SVSCLNNLCLHQSLCIPDQSFSYS 2936
AC + C++GG C G + C C + G C S C ++ C + C+ S+S
Sbjct: 832 ACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNG-SHS 890
Query: 2937 CLCTLGWVGRYCENKTSFSTA 2957
C C +G+ G C + TA
Sbjct: 891 CTCKVGYTGEDCAKELFPPTA 911
Score = 46.2 bits (108), Expect = 5e-04
Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C C++GG+C V + C C + G C V C + CL+ C+ D +Y+C
Sbjct: 353 CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCV-DLVGNYTC 411
Query: 2938 LCTLGWVGRYCE 2949
LC + G CE
Sbjct: 412 LCAEPFKGLRCE 423
Score = 45.8 bits (107), Expect = 7e-04
Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 13/88 (14%)
Query: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
SPC C NGGTC + T +C+C G+ G C V C P + H R
Sbjct: 659 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNG---- 713
Query: 2672 PHGYTCFCPLGTTGIY-CEQALSISDPS 2698
LG +Y C++ S+S PS
Sbjct: 714 -------TRLGAVALYACDRGYSLSAPS 734
Score = 45.4 bits (106), Expect = 9e-04
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC--NQSVSCLNNLCLHQSLCIPDQSFSYS 2936
C CRNGG C G + C C + G C + SC + C + C Y
Sbjct: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCF-HYIGKYK 642
Query: 2937 CLCTLGWVGRYCE 2949
C C G+ GR+CE
Sbjct: 643 CDCPPGFSGRHCE 655
Score = 45.1 bits (105), Expect = 0.001
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 6/110 (5%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVC 2396
C C + G+C C C Y G C+ C +PC NG +C G VC
Sbjct: 757 CRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGA-YVC 815
Query: 2397 LCPYGRSGPLC---TDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYE 2443
CP G G C DA + + + G G ++L S +H E
Sbjct: 816 RCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCE 865
Score = 44.7 bits (104), Expect = 0.001
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C + CRNGG C + CRC + G C V +C ++ C H C +Y C
Sbjct: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC-ESGGGAYLC 853
Query: 2938 LCTLGWVGRYCE 2949
+C + G +CE
Sbjct: 854 VCPESFFGYHCE 865
Score = 44.3 bits (103), Expect = 0.002
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 2097 VAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
+ P C CHNGGTC I ++CDCP F+GR CE
Sbjct: 617 IGKPDSCASGPCHNGGTCFHY-----IGKYKCDCPPGFSGRHCE 655
Score = 43.9 bits (102), Expect = 0.003
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 10/87 (11%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V C +SPC +GG C G + C C + G C ETVS DP P C
Sbjct: 830 VDACDSSPCQ-----HGGRCESGGGAYLCVCPESFFGYHC-ETVS--DPCFSSP--CGGR 879
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQAL 2692
C++ ++C C +G TG C + L
Sbjct: 880 GYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 43.5 bits (101), Expect = 0.003
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS--CLNNLCLHQSLCIPDQSFSYS 2936
C + C NGG C + +++C C + G C ++ C + C + C + Y
Sbjct: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTC-KEAGGEYH 603
Query: 2937 CLCTLGWVGRYCE 2949
C C + GR+CE
Sbjct: 604 CSCPYRFTGRHCE 616
Score = 42.7 bits (99), Expect = 0.006
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 2091 TSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
T + S + PS C D C NGG+C A S+ C+CP F G+ CEK
Sbjct: 533 TDHNASHSLPSPCDSDPCFNGGSCDA-----HDDSYTCECPRGFHGKHCEK 578
Score = 42.4 bits (98), Expect = 0.007
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 14/88 (15%)
Query: 2879 CGYNT--------CRNGG----ECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQS 2925
CG+ T C NGG +C +++C CL + G C+ V+ C + C +
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 2926 LCIPDQSFSYSCLCTLGWVGRYCENKTS 2953
C + S+ C C G+ G CE S
Sbjct: 325 TCTHGIN-SFRCQCPAGFGGPTCETAQS 351
Score = 42.4 bits (98), Expect = 0.007
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 8/60 (13%)
Query: 2098 AAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE---KDAGLFFPSFNGNS 2154
A P +C C NGGTC + G + C CP FTGR CE D+ P NG +
Sbjct: 579 ARPHLCSSGPCRNGGTCKE---AGG--EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGT 633
Score = 42.4 bits (98), Expect = 0.007
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 2858 LQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCL 2917
LQL E G+K ++G+ G C N C+NGG C SC C P + G C + +
Sbjct: 1294 LQLPEHGSK---DIGNVPGN-CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV 1349
Query: 2918 NNLC 2921
+ C
Sbjct: 1350 SRPC 1353
Score = 42.0 bits (97), Expect = 0.010
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 7/60 (11%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQF----ASCE-NNPCGNGATCVPKSGTDIVCLC 2398
CRN G C+ N L C+CP + G LC+F C N C +G C+ G+ +C+C
Sbjct: 474 CRNGGRCLGANTTL-CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGS-YLCVC 531
Score = 42.0 bits (97), Expect = 0.010
Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1008 CLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPC 1051
C PC + G C+ G + ++CDC GF G CE A +S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL-ACIKVSRPC 1353
Score = 41.6 bits (96), Expect = 0.013
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 11/62 (17%)
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQN-----------CSEEINECDSDPCMNGGL 823
C NPC+N TC ++ C+C G+ G+ C+ +E + P GG+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 824 CH 825
CH
Sbjct: 1371 CH 1372
Score = 41.6 bits (96), Expect = 0.013
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPC 975
CS PC+N GTCV + C+C P + G CEL K PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVS-RPC 1353
Score = 40.4 bits (93), Expect = 0.028
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 14/47 (29%)
Query: 685 CASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCE 731
C+ +PC+NG TC+ PG D SC C PG+ G RCE
Sbjct: 1311 CSENPCQNGGTCV--PG------------ADAHSCDCGPGFKGRRCE 1343
Score = 39.7 bits (91), Expect = 0.048
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 5/38 (13%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
C C NGGTC + GI SF+C CP F G CE
Sbjct: 315 CASQPCQNGGTC-----THGINSFRCQCPAGFGGPTCE 347
Score = 39.7 bits (91), Expect = 0.048
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 8/103 (7%)
Query: 2854 NNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS 2913
N + + + G G + D D C + C NGG C ++C C + G C
Sbjct: 368 NGSAVCVCQAGYTGAACEMDVDD--CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETG 425
Query: 2914 -----VSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENK 2951
+CL+ C + C+ D Y C C G++G C +
Sbjct: 426 DHPVPDACLSAPCHNGGTCV-DADQGYVCECPEGFMGLDCRER 467
Score = 39.3 bits (90), Expect = 0.062
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 2879 CGYNT-CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
C NT C +GG C +G ++ C C D + S C ++ C + C SY+C
Sbjct: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS-PCDSDPCFNGGSCDAHDD-SYTC 565
Query: 2938 LCTLGWVGRYCE 2949
C G+ G++CE
Sbjct: 566 ECPRGFHGKHCE 577
Score = 39.3 bits (90), Expect = 0.062
Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECI 1203
CS +PC +G C + + C C PG+ G C EL CI
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC--ELACI 1347
Score = 38.5 bits (88), Expect = 0.11
Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 2598 GHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC 2645
G + G G C +PC NGGTC+ + C+C G+KG C
Sbjct: 1300 GSKDIGNVPGNCSENPCQ-----NGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 38.1 bits (87), Expect = 0.14
Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 970 CKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPC 1013
C +PC + CV D ++C C PG+ G CE+ + +S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 37.0 bits (84), Expect = 0.31
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 18/104 (17%)
Query: 1120 NCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDH 1179
NC+E C NGG CV G C C PGF G+ CE+ + S PC
Sbjct: 1310 NCSENP-----CQNGGTCVPG-ADAHSCDCGPGFKGRRCELACIKV-SRPCTRLFS---- 1358
Query: 1180 INGYVCKCQPGWSGHHCENELECIPNSCVH-ELCMENEPGSTCL 1222
K P W G C + + + VH ++C + ST L
Sbjct: 1359 ----ETKAFPVWEGGVCHHVYKRVYR--VHQDICFKESCESTSL 1396
Score = 37.0 bits (84), Expect = 0.31
Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 1082 DCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEP------ELNSVICLNGG 1135
+C+ PC N G C A +C C G+ G CE + + P E + GG
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
Query: 1136 IC 1137
+C
Sbjct: 1370 VC 1371
Score = 36.6 bits (83), Expect = 0.40
Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLCIPDQSFSYSC 2937
C C +GG C + C C + G C + C + C + C + +Y C
Sbjct: 757 CRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSC-RNLPGAYVC 815
Query: 2938 LCTLGWVGRYCENK 2951
C G+VG +CE +
Sbjct: 816 RCPAGFVGVHCETE 829
Score = 36.6 bits (83), Expect = 0.40
Identities = 25/56 (44%), Positives = 29/56 (51%), Gaps = 7/56 (12%)
Query: 2374 SCENNPCGNGATCVPKSGTDI-VCLCPYGRSGPLCTDA-INITQP---RFSGTDAF 2424
+C NPC NG TCVP G D C C G G C A I +++P FS T AF
Sbjct: 1310 NCSENPCQNGGTCVP--GADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAF 1363
Score = 36.2 bits (82), Expect = 0.53
Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 5/41 (12%)
Query: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
P C ++ C NGGTC G + CDC F GR CE
Sbjct: 1308 PGNCSENPCQNGGTC-----VPGADAHSCDCGPGFKGRRCE 1343
Score = 35.4 bits (80), Expect = 0.90
Identities = 14/38 (36%), Positives = 16/38 (42%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC 2916
C + C NGG C T F C C + G C V C
Sbjct: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC 698
Score = 35.0 bits (79), Expect = 1.2
Identities = 18/75 (24%), Positives = 32/75 (42%), Gaps = 11/75 (14%)
Query: 246 PPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS----AKPCVSL 301
P K+ + G C + C +G +++ C+C F G CE++ ++PC L
Sbjct: 1297 PEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRL 1356
Query: 302 L-------FWKRGIC 309
W+ G+C
Sbjct: 1357 FSETKAFPVWEGGVC 1371
Score = 35.0 bits (79), Expect = 1.2
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 5/37 (13%)
Query: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNC 253
CS PC+N G+C+ + A+ C C P F G+ C
Sbjct: 1311 CSENPCQNGGTCVPGAD-----AHSCDCGPGFKGRRC 1342
Score = 35.0 bits (79), Expect = 1.2
Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
Query: 858 NPCRNNSTCLALVDANQHCICREEFEGKNCEI 889
NPC+N TC+ DA+ C C F+G+ CE+
Sbjct: 1314 NPCQNGGTCVPGADAHS-CDCGPGFKGRRCEL 1344
Score = 34.7 bits (78), Expect = 1.5
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 5/42 (11%)
Query: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
P C CHNGGTC + G V C+CP F G C +
Sbjct: 430 PDACLSAPCHNGGTC--VDADQGYV---CECPEGFMGLDCRE 466
Score = 34.7 bits (78), Expect = 1.5
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 13/77 (16%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV----SCLN-NLCLHQSLCIPDQS 2932
AC C NGG C + C C + G C + V C N CL + +
Sbjct: 432 ACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTL---- 487
Query: 2933 FSYSCLCTLGWVGRYCE 2949
C C LG+ G CE
Sbjct: 488 ----CQCPLGFFGLLCE 500
Score = 34.7 bits (78), Expect = 1.5
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 2910 CNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
C + C + CLH C D+ Y CLC+ G+ G +CE
Sbjct: 751 CLEIDECRSQPCLHGGSC-QDRVAGYLCLCSTGYEGAHCE 789
Score = 34.7 bits (78), Expect = 1.5
Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCE-NNPC 2380
C+ + C+N GTC+ + C+C + G+ C+ A + + PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 33.1 bits (74), Expect = 4.4
Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 14/94 (14%)
Query: 369 SIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLN-EEWCFN 427
++ +C P +N TC + C C GF + CE A C+ C
Sbjct: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELA----------CIKVSRPCTR 1355
Query: 428 IIGRFKYVCIPGCTKNPCWFL-KNVYLIHQHLCY 460
+ K P C + K VY +HQ +C+
Sbjct: 1356 LFSETK--AFPVWEGGVCHHVYKRVYRVHQDICF 1387
Score = 32.7 bits (73), Expect = 5.8
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 5/44 (11%)
Query: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
APS C + C NGGTC F C C + GR C+ +
Sbjct: 657 APSPCFRSPCVNGGTC-----EDRDTDFFCHCQAGYMGRRCQAE 695
Score = 32.3 bits (72), Expect = 7.6
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 1/45 (2%)
Query: 893 DCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
+C CQ+ G C + C C PGF G CE+ + S PC
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 336 bits (862), Expect = 2e-91
Identities = 164/468 (35%), Positives = 238/468 (50%), Gaps = 43/468 (9%)
Query: 764 EGNFCEQESNECKMNPCKNNSTCTDLYKSYRCEC--TSGWTGQNCSEEINECDSDPCMNG 821
+ +FC + + C N C+NNSTC D K C C T+ ++C + C S+PC
Sbjct: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
Query: 822 GLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREE 881
C + F+C CPP Y+G C C N C++ C CIC
Sbjct: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCG--KNSCQHGGICHQ-DPIYPVCICPAG 139
Query: 882 FEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNG 941
+ G+ CEID +C CQ+ C+D ++ + C C PG+ G C++E++EC+S+PCKN
Sbjct: 140 YAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEA 199
Query: 942 TCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINC 1001
TC++ R+ C C Y G CEL++++C PCL+ C Y C CAPG+ G +C
Sbjct: 200 TCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC 259
Query: 1002 EINLDECLSEPCLHDGVCIDGINHYTCDCK-SGFFGTHCETNANDCLSNPC-LHGRCTEL 1059
E+N DEC S+PCLH G+C+DG N Y+C+C SGF GTHCET C S PC + C +
Sbjct: 260 ELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319
Query: 1060 INEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQK--------------------SAH 1099
++ Y C C T QC+I +N+C S PC + G C + A
Sbjct: 320 VDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEAS 379
Query: 1100 GFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRC------LPGF 1153
G+ CIC G+TG +CE+ ++ C +S C NGG C + PG+ + C C +
Sbjct: 380 GYVCICQPGFTGIHCEEDVNEC-----SSNPCQNGGTCENLPGN-YTCHCPFDNLSRTFY 433
Query: 1154 SGQFCEININECSSSPCLHGADCEDHI----NGYVCKCQPGWSGHHCE 1197
G+ C + C+ CL+ C H +G+ C C G++G CE
Sbjct: 434 GGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 323 bits (828), Expect = 2e-87
Identities = 161/468 (34%), Positives = 239/468 (51%), Gaps = 49/468 (10%)
Query: 730 CEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF---CEQESNECKMNPCKNNSTC 786
C ++ C+ N+C++NSTCKD C C SD N C+ + C NPC+ ++TC
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSC-SDTANNLDKDCDNMKDPCFSNPCQGSATC 85
Query: 787 --TDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQ 844
T +S+ C+C G++G C I C + C +GG+CH+ P VC+CP Y G+
Sbjct: 86 VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQD--PIYPVCICPAGYAGR 143
Query: 845 FCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGD 904
FC ++ C +PC+N + C +D C C ++G++C+++V +C C++
Sbjct: 144 FCEIDHDEC--ASSPCQNGAVCQDGID-GYSCFCVPGYQGRHCDLEVDECASDPCKNEAT 200
Query: 905 CEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE 964
C + + + CIC +SG CE+EI+EC S+PC N TC D +FC+C P + G CE
Sbjct: 201 CLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
Query: 965 LDVNKCKISPCLDEENCVYRTDGYNCLC-APGYTGINCEINLDECLSEPCLHDGVCIDGI 1023
L+ ++C PCL CV + Y+C C G+TG +CE + C S+PC ++ C D +
Sbjct: 261 LNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 1024 NHYTCDCKSGFFGTHCETNANDCLSNPC-LHGRCTELINE-------------------- 1062
++YTC C G+ G CE + N+C SNPC +G C EL +E
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 1063 YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICP------RGYTGAYCEK 1116
Y C C T C+ +N+C+S PC N G C+ +TC CP Y G C
Sbjct: 381 YVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440
Query: 1117 SIDNCAEPELNSVICLNGGICV----DGPGHTFDCRCLPGFSGQFCEI 1160
+ C + CLN G C+ DG H F C C G++G CEI
Sbjct: 441 ILLGCTHQQ-----CLNNGTCIPHFQDGQ-HGFSCLCPSGYTGSLCEI 482
Score = 305 bits (781), Expect = 5e-82
Identities = 165/507 (32%), Positives = 229/507 (45%), Gaps = 75/507 (14%)
Query: 636 ERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKC--VPGFKGTQCEIDIDECASHPCKNG 693
+ + C + C S SC+N +T C C+ D C S+PC+
Sbjct: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
Query: 694 ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHL 753
ATC++ PG F C C PGY G CE I C N+C+H C +
Sbjct: 83 ATCVNTPGE------------RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPI 130
Query: 754 SYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINEC 813
C+C + + G FCE + +EC +PC+N + C D Y C C G+ G++C E++EC
Sbjct: 131 YPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC 190
Query: 814 DSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN 873
SDPC N C G++ C+CP Y+G C + C PC N +TC + A
Sbjct: 191 ASDPCKNEATCLNEI--GRYTCICPHNYSGVNCELEIDEC--WSQPCLNGATCQDALGA- 245
Query: 874 QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICR-PGFSGSLCEIEINEC 932
C C F G +CE++ +C C G C D N + C C GF+G+ CE + C
Sbjct: 246 YFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
Query: 933 SSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCV---------- 982
S+PC NN TC D + + C+C P Y G CE+D+N+C +PC CV
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR 365
Query: 983 ----------YRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKS 1032
+ GY C+C PG+TGI+CE +++EC S PC + G C + +YTC C
Sbjct: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPF 425
Query: 1033 GFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEG 1092
D LS GR C + CT C+N G
Sbjct: 426 ------------DNLSRTFYGGR-------------------DCSDILLGCTHQQCLNNG 454
Query: 1093 FC----QKSAHGFTCICPRGYTGAYCE 1115
C Q HGF+C+CP GYTG+ CE
Sbjct: 455 TCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 283 bits (724), Expect = 2e-75
Identities = 162/475 (34%), Positives = 223/475 (46%), Gaps = 57/475 (12%)
Query: 565 ENTTDDQENECQHEAVCKDEINRPRCSCS--LSYIGRLCVVNVDYCLGNH---SISVHGL 619
+N T N CQ+ + CKD CSCS + + + C D C N S +
Sbjct: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88
Query: 620 CLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE 679
S C C Y ICE C SC++G Y C G+ G CE
Sbjct: 89 PGERSFLCKCP--PGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 680 IDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
ID DECAS PC+NGA C D +DG+SC C PGY G C+ ++D+C
Sbjct: 147 IDHDECASSPCQNGAVCQDG--------------IDGYSCFCVPGYQGRHCDLEVDECAS 192
Query: 740 NACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTS 799
+ C++ +TC + Y C+C ++ G CE E +EC PC N +TC D +Y C+C
Sbjct: 193 DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAP 252
Query: 800 GWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPL-YTGQFCHQRYNLCDLLHN 858
G+ G +C +EC S PC++GGLC + ++ C C +TG C LC
Sbjct: 253 GFLGDHCELNTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLC--WSK 308
Query: 859 PCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDM---------- 908
PC NN+TC VD N C C + G CEID+ +C CQ G+C ++
Sbjct: 309 PCHNNATCEDSVD-NYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRIT 367
Query: 909 ----------VNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPE- 957
+ + CIC+PGF+G CE ++NECSS PC+N GTC +L + C+C +
Sbjct: 368 GLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
Query: 958 -----YHGPFCELDVNKCKISPCLDEENCVYR----TDGYNCLCAPGYTGINCEI 1003
Y G C + C CL+ C+ G++CLC GYTG CEI
Sbjct: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 242 bits (618), Expect = 4e-63
Identities = 130/382 (34%), Positives = 183/382 (47%), Gaps = 38/382 (9%)
Query: 887 CEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG--SLCEIEINECSSEPCKNNGTCV 944
C + CL SCQ+ C+D + C C + C+ + C S PC+ + TCV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 945 DLTNR--FFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCE 1002
+ F C C P Y G CE + C + C C C+C GY G CE
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH-GRCTELIN 1061
I+ DEC S PC + VC DGI+ Y+C C G+ G HC+ ++C S+PC + C I
Sbjct: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
Query: 1062 EYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNC 1121
Y C C + + C+++I++C S PC+N CQ + + C C G+ G +CE + D C
Sbjct: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
Query: 1122 AEPELNSVICLNGGICVDGPGHTFDCRCL-PGFSGQFCEININECSSSPCLHGADCEDHI 1180
A S CL+GG+CVDG + C C GF+G CE + C S PC + A CED +
Sbjct: 267 A-----SQPCLHGGLCVDGENR-YSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 1181 NGYVCKCQPGWSGHHCENEL-ECIPNSCVH-----ELCMENE----------------PG 1218
+ Y C C PG++G CE +L EC N C EL E + G
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 1219 STCLCTPGFMTCSIGLLCGDEI 1240
C+C PGF G+ C +++
Sbjct: 381 YVCICQPGF----TGIHCEEDV 398
Score = 178 bits (452), Expect = 7e-44
Identities = 75/200 (37%), Positives = 115/200 (57%), Gaps = 3/200 (1%)
Query: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINE 1062
+ L+ C S PCLH G C D + Y C C G+ G HCE N ++C SNPC+HG C++ +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
Query: 1063 YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKS--IDN 1120
Y C+C+ T C++ I++C S C N C +G++C+C +TG +C +S
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 1121 CAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHI 1180
E ++ C NGG C + C C PGF+G++CE +I+EC+S PC++G C+D +
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTE-LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 1181 NGYVCKCQPGWSGHHCENEL 1200
N + C C ++G CE +L
Sbjct: 1317 NKFQCLCDVAFAGERCEVDL 1336
Score = 160 bits (404), Expect = 2e-38
Identities = 74/202 (36%), Positives = 110/202 (54%), Gaps = 13/202 (6%)
Query: 773 NECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQ 832
N C NPC + C D+Y SY C C GW+G++C I+EC S+PC++G C +
Sbjct: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRV--AA 1197
Query: 833 FVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE---- 888
+ C C P YTG C + C + C N +TC++ + C+C F GK C
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQ--SHQCANGATCISHTNGYS-CLCFGNFTGKFCRQSRL 1254
Query: 889 ---IDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVD 945
+ + L+C + G+C + +C+CRPGF+G CE +I+EC+S+PC N G C D
Sbjct: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
Query: 946 LTNRFFCNCEPEYHGPFCELDV 967
L N+F C C+ + G CE+D+
Sbjct: 1315 LLNKFQCLCDVAFAGERCEVDL 1336
Score = 158 bits (400), Expect = 7e-38
Identities = 73/220 (33%), Positives = 113/220 (51%), Gaps = 12/220 (5%)
Query: 927 IEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD 986
+++N C+S PC + G C D+ + + C+C + G CEL++++C +PC+ NC R
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVA 1196
Query: 987 GYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETN---- 1042
Y+C C PGYTG+NCE+++D C S C + CI N Y+C C F G C +
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 1043 ---ANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA 1098
N+ + C + G CTE E C C T C+ I++C S PC+N G CQ
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 1099 HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICV 1138
+ F C+C + G CE + A+ ++ + G + V
Sbjct: 1317 NKFQCLCDVAFAGERCEVDL---ADDLISDIFTTIGSVTV 1353
Score = 151 bits (382), Expect = 9e-36
Identities = 84/269 (31%), Positives = 124/269 (46%), Gaps = 35/269 (13%)
Query: 596 YIGRLCVVNVDYCLGNHS-ISVHGLCLALSHNCNCSGLQRYERNICEIDTED-------- 646
Y+G + N+ G S I + G+ L+ N + + E +I T
Sbjct: 1081 YVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQL 1140
Query: 647 --CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYF 704
C S C +G + + C G+ G CE++IDEC S+PC +G C D+
Sbjct: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDR----- 1194
Query: 705 CQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWE 764
V + C C PGY G+ CE DID+C + C + +TC Y C+C ++
Sbjct: 1195 ---------VAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFT 1245
Query: 765 GNFCEQE-------SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP 817
G FC Q NE C N CT+ +C C G+TG+ C ++I+EC SDP
Sbjct: 1246 GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP 1305
Query: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFC 846
C+NGGLC + + +F CLC + G+ C
Sbjct: 1306 CVNGGLCQD--LLNKFQCLCDVAFAGERC 1332
Score = 146 bits (369), Expect = 3e-34
Identities = 84/266 (31%), Positives = 117/266 (43%), Gaps = 27/266 (10%)
Query: 1001 CEINLDECLSEPCLHDGVCIDGINHYTCDCK--SGFFGTHCETNANDCLSNPCL-HGRCT 1057
C N CLS C ++ C D C C + C+ + C SNPC C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 1058 ELINE--YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCE 1115
E + C C + T C+ I C C + G C + CICP GY G +CE
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 1116 KSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGAD 1175
D CA S C NG +C DG + C C+PG+ G+ C++ ++EC+S PC + A
Sbjct: 147 IDHDECA-----SSPCQNGAVCQDGIDG-YSCFCVPGYQGRHCDLEVDECASDPCKNEAT 200
Query: 1176 CEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVHELCMENEPGS-TCLCTPGFM----- 1228
C + I Y C C +SG +CE E+ EC C++ ++ G+ C C PGF+
Sbjct: 201 CLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
Query: 1229 ---------TCSIGLLCGDEIRRITC 1245
C G LC D R +C
Sbjct: 261 LNTDECASQPCLHGGLCVDGENRYSC 286
Score = 141 bits (356), Expect = 9e-33
Identities = 167/744 (22%), Positives = 261/744 (35%), Gaps = 142/744 (19%)
Query: 161 LGLRLNVTVKQQFCQESLS---SEFCSGHGKCLSEAWSKTYSCHCQPPFSG--KYCQEL- 214
L L + +K FC ++ + S C + C + +SK C C + K C +
Sbjct: 14 LSFSLLIYIKNSFCNKNNTRCLSNSCQNNSTC--KDFSKDNDCSCSDTANNLDKDCDNMK 71
Query: 215 DACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNIT 274
D C PC+ + +C+N E+++ C C P ++G C IG C + C HG +
Sbjct: 72 DPCFSNPCQGSATCVNTP---GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQD 128
Query: 275 SNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVS 334
+C C ++G FCE+ C S +C + Y+ C G ++ + +V
Sbjct: 129 PIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVD 188
Query: 335 EFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPC 394
E + PC+N C+ CIC ++ + C+ C S P N ATC+ Y C
Sbjct: 189 ECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 395 SCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVC-------------IPGCT 441
C GF +CE D C S CL+ C + R+ C +P C
Sbjct: 249 DCAPGFLGDHCELNTDECA--SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCW 306
Query: 442 KNPCWFLKNVY-LIHQHLCYCGVTFHGI-------------CQDKG-------------- 473
PC + + C+C + G CQ G
Sbjct: 307 SKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRI 366
Query: 474 ---PAQFEY--------VWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNS 522
P+ F Y + Q GF G E+ D + C T N P +
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGFTGIHCEE-----DVNECSSNPCQNGGTCENLPGNYTC 421
Query: 523 SCWFPHEG----------------TKEICANGCSCLSE-EDSQE-YRYLCFLRWAGNMYL 564
C F + T + C N +C+ +D Q + LC + G++
Sbjct: 422 HCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Query: 565 ENTTDDQENE----------CQHEAVCKDEINRPRC---SCSLSYIGRLCVVNVDYCLGN 611
TT E + +VC + + L R V ++ G
Sbjct: 482 IATTLSFEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSGY 541
Query: 612 HSISVH-----GLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFF 666
+S+ + L +SHN + E E T SCK
Sbjct: 542 IHLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKE------------ 589
Query: 667 RKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV 726
KC+ T E D CA G + N +++ ++ P +V
Sbjct: 590 -KCIAKAP-TPLESDQSICAFQNSFLGGLPVGMTSNGVA-------LLNFYNMPSTPSFV 640
Query: 727 GIRCEQDID-DCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNST 785
G C QDI D E+ S+ L++ CV DW C+ PC++
Sbjct: 641 G--CLQDIKIDWNHITLENISSGSSLNVKAGCV-RKDW-----------CESQPCQSRGR 686
Query: 786 CTDLYKSYRCECTSGWTGQNCSEE 809
C +L+ SY+C+C + G NC E
Sbjct: 687 CINLWLSYQCDCHRPYEGPNCLRE 710
Score = 127 bits (320), Expect = 1e-28
Identities = 68/196 (34%), Positives = 98/196 (50%), Gaps = 21/196 (10%)
Query: 1044 NDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFT 1102
N C SNPCLHG C ++ + Y CSC + C++ I++C S PC++ G C +
Sbjct: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYH 1199
Query: 1103 CICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHT--FDCRCLPGFSGQFCE- 1159
C C GYTG CE IDNC + C NG C+ HT + C C F+G+FC
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQ-----CANGATCIS---HTNGYSCLCFGNFTGKFCRQ 1251
Query: 1160 ------ININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVH-EL 1211
+ NE ++ C +G +C + C C+PG++G CE ++ EC + CV+ L
Sbjct: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
Query: 1212 CMENEPGSTCLCTPGF 1227
C + CLC F
Sbjct: 1312 CQDLLNKFQCLCDVAF 1327
Score = 126 bits (316), Expect = 4e-28
Identities = 70/223 (31%), Positives = 105/223 (47%), Gaps = 27/223 (12%)
Query: 680 IDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
+ ++ C S+PC +G C D +Y C C P G+ G CE +ID+C
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSC--PL------------GWSGKHCELNIDECFS 1183
Query: 740 NACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTS 799
N C H + C D +Y C C + G CE + + C+ + C N +TC Y C C
Sbjct: 1184 NPCIHGN-CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFG 1242
Query: 800 GWTGQNCSEEI-------NECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNL 852
+TG+ C + NE + C NGG C E + C+C P +TG++C + +
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTE--FQTELKCMCRPGFTGEWCEKDIDE 1300
Query: 853 CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCL 895
C +PC N C L++ Q C+C F G+ CE+D+ D L
Sbjct: 1301 C--ASDPCVNGGLCQDLLNKFQ-CLCDVAFAGERCEVDLADDL 1340
Score = 121 bits (304), Expect = 1e-26
Identities = 112/456 (24%), Positives = 171/456 (37%), Gaps = 88/456 (19%)
Query: 858 NPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICR 917
NPC N C + D + C C GK CE +V+ C F C C+ ++ F CI
Sbjct: 894 NPCHNGGVCHSRWD-DFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIAN 951
Query: 918 PGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFF-------------CNCEPEYHGPFCE 964
F+G +I N +LTN F EPE F
Sbjct: 952 AVFNGQSGQILFR-------SNGNITRELTNITFGFRTRDANVIILHAEKEPE----FLN 1000
Query: 965 LDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSE------------P 1012
+ + ++ L N Y + T +++ + LS+ P
Sbjct: 1001 ISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQMEVDNETP 1060
Query: 1013 CLHDGVCIDGINHYTCDCKSGFFGTHCETN---ANDCLSN-----------PCLHGRCTE 1058
+ + +N + D + G N CLS +HG +
Sbjct: 1061 FVTSTIATGSLN-FLKDNTDIYVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINK 1119
Query: 1059 LINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
E + T C +++N C S PC++ G C+ + C CP G++G +CE +I
Sbjct: 1120 PQEEQFLKISTNSVVTGC-LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1178
Query: 1119 DNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCED 1178
D C S C++G C D + C C PG++G CE++I+ C S C +GA C
Sbjct: 1179 DECF-----SNPCIHGN-CSDRVA-AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCIS 1231
Query: 1179 HINGYVCKCQPGWSGHHCENELECIPNS-CVHEL----------CMENEPGSTCLCTPGF 1227
H NGY C C ++G C +P++ C +E C E + C+C PGF
Sbjct: 1232 HTNGYSCLCFGNFTGKFCRQSR--LPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
Query: 1228 M--------------TCSIGLLCGDEIRRITCLTPI 1249
C G LC D + + CL +
Sbjct: 1290 TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325
Score = 120 bits (300), Expect = 3e-26
Identities = 69/245 (28%), Positives = 105/245 (42%), Gaps = 33/245 (13%)
Query: 573 NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGL 632
N+ Q E K N C +L V N + CL G C + + +CS
Sbjct: 1118 NKPQEEQFLKISTNSVVTGCL-----QLNVCNSNPCLHG------GNCEDIYSSYHCSCP 1166
Query: 633 QRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKN 692
+ CE++ ++C S C +G S + Y C PG+ G CE+DID C SH C N
Sbjct: 1167 LGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCT-CEPGYTGVNCEVDIDNCQSHQCAN 1225
Query: 693 GATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQD-IDDCILN------ACEHN 745
GATCI +G+SCLC + G C Q + + C +
Sbjct: 1226 GATCISH--------------TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNG 1271
Query: 746 STCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQN 805
C + +C+C + G +CE++ +EC +PC N C DL ++C C + G+
Sbjct: 1272 GNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGER 1331
Query: 806 CSEEI 810
C ++
Sbjct: 1332 CEVDL 1336
Score = 114 bits (284), Expect = 2e-24
Identities = 198/889 (22%), Positives = 339/889 (38%), Gaps = 209/889 (23%)
Query: 1888 YYGDSYLEFQNVALNPQN---NISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTL 1944
+ GD +L ++ ++ + NI+L FQT LLL+ F++L + +G +
Sbjct: 488 FEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRD-----VFVKLELLSGYI 542
Query: 1945 KYHFYCPGEAK---FKSINTT------VRVDNGQKYTLLIRQEL--DPCNAEL-TILGRN 1992
++K F S NT+ V V + TL + + + C A+ T L +
Sbjct: 543 HLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESD 602
Query: 1993 TQICESINHVLGKPLP---KSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSF 2049
IC N LG LP S V + F MP +F GC++ I+I+ W
Sbjct: 603 QSICAFQNSFLGG-LPVGMTSNGVALLNF------YNMP-STPSFVGCLQDIKID-WNHI 653
Query: 2050 IPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCH 2109
++N S G L+ A V W C+ C
Sbjct: 654 ----TLENI------SSGSSLNVKAGCVRKD---------W------------CESQPCQ 682
Query: 2110 NGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD--AGLFFPSFNGNSYLELPFLKFVLEK 2167
+ G C ++LS +QCDC + G C ++ AG F + ++ F L++
Sbjct: 683 SRGRCINLWLS-----YQCDCHRPYEGPNCLREYVAGRFGQDDSTG------YVIFTLDE 731
Query: 2168 EHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTV-- 2225
+ T+++ + ++T +G +L N Q++ ++L GR ++ NS ++
Sbjct: 732 SYGDTISLSMFVRTLQPSGLLLALE--NSTYQYIRVWLERGRLAML--TPNSPKLVVKFV 787
Query: 2226 --SANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFES 2283
N + + P I + G + ++K D
Sbjct: 788 LNDGNVHLISLKIKPYKIELYQSSQNLGFISASTWK------IEKGDV------------ 829
Query: 2284 MFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNK--EFF-----------IIDEARHGKN 2330
+++G +P + G F+GCI D+++NN+ EFF ++ G
Sbjct: 830 IYIGGLPDKQETELNGG---FFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCA 886
Query: 2331 IENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPK 2389
+N C + C N G C S ++ C CP L SGK C+ C +PC +GA C P
Sbjct: 887 GDNS----CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPV 942
Query: 2390 -SGTDIVCLCPY-GRSGPLCTDAI-NITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHL 2446
G + + + G+SG + + NIT+ + T FG+ + A + I H E
Sbjct: 943 LQGFECIANAVFNGQSGQILFRSNGNITRELTNIT--FGFRTRDA----NVIILHAEKEP 996
Query: 2447 KFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN 2506
+F + ++Q++ +FF Q G+ ++ +N + L ++PL+
Sbjct: 997 EFL----NISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSM------TDPLS 1046
Query: 2507 LSLGVHTVHLGKFFQEGWLKVDDHKNK---SIIAPGRLVGLNVFSQFYVGGYSEYTPDLL 2563
+ W D++ S IA G L L + YVG
Sbjct: 1047 QT-------------SRWQMEVDNETPFVTSTIATGSLNFLKDNTDIYVGD--------- 1084
Query: 2564 PNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSV---------GQCHASPC 2614
D G QGC+ T+++ +F + P + + G + C
Sbjct: 1085 -RAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVC 1143
Query: 2615 SLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS---------------------TCD 2653
+ C +GG C + +S +C+C GW G C + TC+
Sbjct: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCE 1203
Query: 2654 P-----------EHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQA 2691
P ++ H C+ GATCIS +GY+C C TG +C Q+
Sbjct: 1204 PGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQS 1252
Score = 112 bits (279), Expect = 8e-24
Identities = 199/890 (22%), Positives = 313/890 (35%), Gaps = 165/890 (18%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLK 2162
C C N GTC F G F C CP +TG CE L SF G+ +L ++K
Sbjct: 445 CTHQQCLNNGTCIPHF-QDGQHGFSCLCPSGYTGSLCEIATTL---SFEGDGFL---WVK 497
Query: 2163 FVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNI 2222
I L +T +L+ + + F+ L L+ G + N +
Sbjct: 498 SGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDV---FVKLELLSGYIHLSIQVNNQSKV 554
Query: 2223 LT-VSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYF 2281
L +S N S F + + C + A P++ S S F
Sbjct: 555 LLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLE------SDQSICAF 608
Query: 2282 ESMFLGHIPANVQIHKKA-------GPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENC 2334
++ FLG +P + + A F GC+ D++++
Sbjct: 609 QNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKID------------------- 649
Query: 2335 HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDI 2394
W +H+ N + S + N+ C R CE+ PC + C+
Sbjct: 650 ---W--NHITLENISSGS-SLNVKAGCVRK--------DWCESQPCQSRGRCI-NLWLSY 694
Query: 2395 VCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNH 2454
C C GP C RF D+ GY F D F Q +
Sbjct: 695 QCDCHRPYEGPNCLR--EYVAGRFGQDDSTGYVIFTLDESYGDTISLSMFVRTLQPSGLL 752
Query: 2455 SALQNNLIFFTG---QKGHGLNGDDFLAVGLLNG-SVVYSYNLGSG---IASIRSEPLNL 2507
AL+N+ + ++G LA+ N +V + L G + S++ +P +
Sbjct: 753 LALENSTYQYIRVWLERGR-------LAMLTPNSPKLVVKFVLNDGNVHLISLKIKPYKI 805
Query: 2508 SLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGA 2567
L + +LG W I G ++ Y+GG + L G
Sbjct: 806 ELYQSSQNLGFISASTWK----------IEKGDVI--------YIGGLPDKQETELNGGF 847
Query: 2568 DFKNGFQGCIFTLQVRTEKDGHFRG-LGNPEGHPNAGRSVGQCHA-SPCSLMKCGNGGTC 2625
F+GCI +++ + F N +P C + C C NGG C
Sbjct: 848 -----FKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGGVC 902
Query: 2626 IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTG 2685
C+C G C E V C P C GA C + G+ C
Sbjct: 903 HSRWDDFSCSCPALTSGKACEE-VQWCG--FSP---CPHGAQCQPVLQGFECIA----NA 952
Query: 2686 IYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSG 2745
++ Q+ I FRSN R+ T+I F+ A+ I+ +A +
Sbjct: 953 VFNGQSGQIL---FRSN--------GNITRELTNITFGFRTRDANVIILHAEKE-----P 996
Query: 2746 DFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVG-----AEGYLDLD 2800
+FL IS+ +S + + G+ +L ++N TWH + + +++D
Sbjct: 997 EFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQMEVD 1056
Query: 2801 GIN--VTEKAST-KMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINN-- 2855
VT +T ++ L NTD Y+G AI+N G QGC+ + I
Sbjct: 1057 NETPFVTSTIATGSLNFLKDNTDIYVGD---------RAIDNIK-GLQGCLSTIEIGGIY 1106
Query: 2856 --------------QELQLTEFGAKGGSNVGDC-DGTACGYNTCRNGGECTVNGTTFSCR 2900
QE Q + S V C C N C +GG C +++ C
Sbjct: 1107 LSYFENVHGFINKPQEEQFLKISTN--SVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCS 1164
Query: 2901 CLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
C W+G C ++ C +N C+H + D+ +Y C C G+ G CE
Sbjct: 1165 CPLGWSGKHCELNIDECFSNPCIHGN--CSDRVAAYHCTCEPGYTGVNCE 1212
Score = 104 bits (260), Expect = 1e-21
Identities = 65/229 (28%), Positives = 91/229 (39%), Gaps = 40/229 (17%)
Query: 179 SSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDE 237
+S C G C E +Y C C +SGK+C+ +D C PC + G+C ++
Sbjct: 1144 NSNPCLHGGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDR-----V 1195
Query: 238 QAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKP 297
AY C C P +TG NC I CQ H C +G +N + C C F+G FC S P
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 298 CVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCI 357
+C N + T C NG +C + ++ C+
Sbjct: 1256 ST--------VCGNEKTNLT-----------------------CYNGGNCTEFQTELKCM 1284
Query: 358 CSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
C P FT C+ C S P N C+ + C C F + CE
Sbjct: 1285 CRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 101 bits (252), Expect = 1e-20
Identities = 66/215 (30%), Positives = 90/215 (41%), Gaps = 65/215 (30%)
Query: 573 NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCL--ALSHNCNCS 630
N C H C+D + CSC L + G+ C +N+D C N I HG C +++C C
Sbjct: 1146 NPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI--HGNCSDRVAAYHCTCE 1203
Query: 631 GLQRYERNICEIDTEDCKSASCKNGTTS-THLRGY-----------FFRK---------- 668
Y CE+D ++C+S C NG T +H GY F R+
Sbjct: 1204 --PGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
Query: 669 -----------------------CVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFC 705
C PGF G CE DIDECAS PC NG C D
Sbjct: 1262 EKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD------- 1314
Query: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILN 740
+++ F CLC+ + G RCE D+ D +++
Sbjct: 1315 -------LLNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 94.0 bits (232), Expect = 2e-18
Identities = 58/190 (30%), Positives = 86/190 (45%), Gaps = 22/190 (11%)
Query: 260 CQPHVCFH-GNCSNITSNSFICECDEQFSGPFCEVS-----AKPCVSLLFWKRGICPNSS 313
C + C H GNC +I S S+ C C +SG CE++ + PC+ G C +
Sbjct: 1143 CNSNPCLHGGNCEDIYS-SYHCSCPLGWSGKHCELNIDECFSNPCI------HGNCSDRV 1195
Query: 314 SAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQ-- 371
+AY C G + N E D+ C NG CI +N C+C FT C+ +
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 372 -TSC----ESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCF 426
T C + N C + + + C C GFT + CEK ID C S C+N C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--ASDPCVNGGLCQ 1313
Query: 427 NIIGRFKYVC 436
+++ +F+ +C
Sbjct: 1314 DLLNKFQCLC 1323
Score = 79.0 bits (193), Expect = 7e-14
Identities = 211/1007 (20%), Positives = 334/1007 (33%), Gaps = 205/1007 (20%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFF--PSFNGNSYLELPF 2160
C D C N TC + I + C CP +++G CE + + P NG + +
Sbjct: 190 CASDPCKNEATC-----LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQD--- 241
Query: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQ-FLHLFL-VEGRPSVKYGCGN 2218
+ Y G N + C Q LH L V+G C
Sbjct: 242 -----------ALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTG 290
Query: 2219 S-------QNILTVSANYSINTNAFTPITI-RYTTPV--GSPGVVCMIEMTADGKPPVQK 2268
S + ++ + + + NA ++ YT G G C I++ P Q
Sbjct: 291 SGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQS 350
Query: 2269 KDTEISHASQAYFESMFLGHIPANVQIHKKAGPVY----GFRGCILDLQVNNKEFFIIDE 2324
+ +S+ + + +P++ H+ +G V GF G + VN
Sbjct: 351 NGECVELSSEKQYGR--ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE-------- 400
Query: 2325 ARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECP------RLYSGKLCQ--FASCE 2376
C+ + C+N GTC + N C CP Y G+ C C
Sbjct: 401 --------------CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCT 446
Query: 2377 NNPCGNGATCVP---KSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYS 2433
+ C N TC+P CLCP G +G LC A ++ F G D F + + +
Sbjct: 447 HQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLS---FEG-DGFLWVKSGSVT 502
Query: 2434 RISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL 2493
+ L+FQ + L+ F N D F+ + LL+G + S +
Sbjct: 503 TKGSVC---NIALRFQTVQPMA-----LLLFRS------NRDVFVKLELLSGYIHLSIQV 548
Query: 2494 GSGIASIRSEPLNLSLGV-HTVHLGKFFQEG---WLKVDDHKNKSII-APGRL---VGLN 2545
+ + N S G H V + F E L D K K I AP L +
Sbjct: 549 NNQSKVLLFISHNTSDGEWHFVEV--IFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSIC 606
Query: 2546 VFSQFYVGGYSEYTPDLLPNGADFKN--------GFQGCIFTLQVRTEKDGHFRGLGNPE 2597
F ++GG + NG N F GC+ +++ D + L N
Sbjct: 607 AFQNSFLGG---LPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKI----DWNHITLENIS 659
Query: 2598 GHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC-TETVSTCDPEH 2656
+ G C C + G CI S C+C ++G C E V+ +
Sbjct: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQD 719
Query: 2657 DPPHHCSRGATCISLPHGY--TCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHV 2714
D S G +L Y T + + L + S W+ +
Sbjct: 720 D-----STGYVIFTLDESYGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAM 774
Query: 2715 RKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQ 2774
+L + + DG + + +K I L SS L +
Sbjct: 775 LTPNSPKLVVKFVLNDGNVHLISLKIKPYK-----IELYQSSQNLGF------------- 816
Query: 2775 KVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNP 2834
I+ STW I K + G + +K T++ N F+ G + + L N
Sbjct: 817 ---ISASTWKIEKGDVIYIGG--------LPDKQETEL-----NGGFFKGCIQDVRLNNQ 860
Query: 2835 -MAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVN 2893
+ P + V++N + G +C N C NGG C
Sbjct: 861 NLEFFPNPTN-NASLNPVLVNVTQ--------------GCAGDNSCKSNPCHNGGVCHSR 905
Query: 2894 GTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTS 2953
FSC C +G C + C + C H + C P + C+
Sbjct: 906 WDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQ-GFECI--------------- 949
Query: 2954 FSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGL 3013
+ A F G S N + + T I+ F T +I + +E +FL I +
Sbjct: 950 -ANAVFNGQSGQILFRSNGNITR-ELTNITFGFRTRDANVII----LHAEKEPEFLNISI 1003
Query: 3014 HNQTLKIAVNLGE-----RISVPMSYNNGTFCCNKWHHVVVIQNQTL 3055
+ L + G ++ S N+GT WH V + L
Sbjct: 1004 QDSRLFFQLQSGNSFYMLSLTSLQSVNDGT-----WHEVTLSMTDPL 1045
Score = 71.6 bits (174), Expect = 1e-11
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 16/193 (8%)
Query: 307 GICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLL 366
G C + S+Y CP G S ++ E ++ E PC +G +C C C P +T +
Sbjct: 1152 GNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVN 1210
Query: 367 CKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA-----IDHCKLLSINCLN 421
C+ +C+S N ATC Y C C FT K C ++ + + ++ C N
Sbjct: 1211 CEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYN 1270
Query: 422 EEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVW 481
C K +C PG T W K++ C G G+CQD +F+ +
Sbjct: 1271 GGNCTEFQTELKCMCRPGFTGE--WCEKDIDECASDPCVNG----GLCQDL-LNKFQCLC 1323
Query: 482 QLGFAGSEGEKCQ 494
+ FA GE+C+
Sbjct: 1324 DVAFA---GERCE 1333
Score = 69.3 bits (168), Expect = 6e-11
Identities = 74/299 (24%), Positives = 121/299 (40%), Gaps = 55/299 (18%)
Query: 59 FLGVNTKIDTSGNQAVPQICPLQ-----IQLGDILVISSEPSLQF----PEINLMNVSET 109
FL NT I G++A+ I LQ I++G I + E F E + +S
Sbjct: 1073 FLKDNTDIYV-GDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTN 1131
Query: 110 SFV-GCVQ-NTTTEDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNV 167
S V GC+Q N + L G + +++ S CPLG
Sbjct: 1132 SVVTGCLQLNVCNSNPCLHGGNCEDIYS------------------SYHCSCPLGW---- 1169
Query: 168 TVKQQFCQESLSSEFCSG--HGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKN 224
+ C+ ++ F + HG C Y C C+P ++G C+ ++D C C N
Sbjct: 1170 --SGKHCELNIDECFSNPCIHGNCSDRV--AAYHCTCEPGYTGVNCEVDIDNCQSHQCAN 1225
Query: 225 NGSCINKRENWDEQAYECVCHPPFTGKNC------SEIIGQCQPHV-CFHG-NCSNITSN 276
+CI+ Y C+C FTGK C S + G + ++ C++G NC+ +
Sbjct: 1226 GATCISHTNG-----YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
Query: 277 SFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSE 335
C C F+G +CE C S G+C + + + C + + E D+++
Sbjct: 1281 -LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 67.4 bits (163), Expect = 2e-10
Identities = 60/259 (23%), Positives = 113/259 (43%), Gaps = 27/259 (10%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPD------WAGNTCNQ-SVSCLNNLCLHQSLC 2927
D C N C+NGG C ++C C D + G C+ + C + CL+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTC 456
Query: 2928 IP---DQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISL 2984
IP D +SCLC G+ G CE T+ S F G+ ++ ++ I+L
Sbjct: 457 IPHFQDGQHGFSCLCPSGYTGSLCEIATTLS---FEGDGFL-WVKSGSVTTKGSVCNIAL 512
Query: 2985 NFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKW 3044
F T + L+++ ++ + F+ + L + + +++ + + V + ++ T +W
Sbjct: 513 RFQTVQPMALLLF----RSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISHNT-SDGEW 567
Query: 3045 HHVVVIQNQTLIKAYINNSL---ILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQ 3101
H V VI + + I++S +++ P ++ ++ +LGG G N V
Sbjct: 568 HFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLPVGMTSNGVAL 627
Query: 3102 EIF-----KTNFVGKIKDV 3115
F +FVG ++D+
Sbjct: 628 LNFYNMPSTPSFVGCLQDI 646
Score = 57.4 bits (137), Expect = 2e-07
Identities = 53/232 (22%), Positives = 89/232 (38%), Gaps = 38/232 (16%)
Query: 374 CESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFK 433
C S P + C+ Y CSC G++ K+CE ID C S C++ C + + +
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC--FSNPCIHGN-CSDRVAAYH 1199
Query: 434 YVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKC 493
C PG T C ++ H C G T I G + L F G+ C
Sbjct: 1200 CTCEPGYTGVNCEV--DIDNCQSHQCANGATC--ISHTNGYS------CLCFGNFTGKFC 1249
Query: 494 QGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYL 553
+ + S +E T C NG +C E E + +
Sbjct: 1250 R-----------------------QSRLPSTVCGNEKTNLTCYNGGNC--TEFQTELKCM 1284
Query: 554 CFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNV 605
C + G ++ + + C + +C+D +N+ +C C +++ G C V++
Sbjct: 1285 CRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 56.6 bits (135), Expect = 4e-07
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 2873 DCDGTA--CGYNTCRNGGEC--TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLC 2927
DCD C N C+ C T +F C+C P ++G C ++ SC N C H +C
Sbjct: 66 DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGIC 125
Query: 2928 IPDQSFSYSCLCTLGWVGRYCE 2949
D + C+C G+ GR+CE
Sbjct: 126 HQDPIYPV-CICPAGYAGRFCE 146
Score = 54.7 bits (130), Expect = 1e-06
Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 2877 TACGYN----TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
T CG TC NGG CT T C C P + G C + + C ++ C++ LC D
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLC-QDL 1315
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
+ CLC + + G CE
Sbjct: 1316 LNKFQCLCDVAFAGERCE 1333
Score = 52.8 bits (125), Expect = 5e-06
Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 10/82 (12%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+C +SPC NG C + C C G++G C V C DP C AT
Sbjct: 151 ECASSPCQ-----NGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDP---CKNEAT 200
Query: 2668 CISLPHGYTCFCPLGTTGIYCE 2689
C++ YTC CP +G+ CE
Sbjct: 201 CLNEIGRYTCICPHNYSGVNCE 222
Score = 52.4 bits (124), Expect = 7e-06
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Query: 773 NECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQ 832
N CK NPC N C + + C C + +G+ C EE+ C PC +G C + + G
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQC-QPVLQG- 945
Query: 833 FVCLCPPLYTGQ 844
F C+ ++ GQ
Sbjct: 946 FECIANAVFNGQ 957
Score = 50.8 bits (120), Expect = 2e-05
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 2617 MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
+ C NGG C E T + C C G+ G +C + + C DP C G C L + +
Sbjct: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--ASDP---CVNGGLCQDLLNKFQ 1320
Query: 2677 CFCPLGTTGIYCEQALS 2693
C C + G CE L+
Sbjct: 1321 CLCDVAFAGERCEVDLA 1337
Score = 50.4 bits (119), Expect = 3e-05
Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 25/134 (18%)
Query: 756 QCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDS 815
Q V L++ F +N +NP N T Q C+ + N C S
Sbjct: 853 QDVRLNNQNLEFFPNPTNNASLNPVLVNVT------------------QGCAGD-NSCKS 893
Query: 816 DPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH 875
+PC NGG+CH F C CP L +G+ C + C +PC + + C ++ +
Sbjct: 894 NPCHNGGVCHSRW--DDFSCSCPALTSGKAC-EEVQWCGF--SPCPHGAQCQPVLQGFE- 947
Query: 876 CICREEFEGKNCEI 889
CI F G++ +I
Sbjct: 948 CIANAVFNGQSGQI 961
Score = 49.3 bits (116), Expect = 6e-05
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 7/100 (7%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
P ++ + C C +GG C + C C G+ G FC D +
Sbjct: 100 PGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-----EIDHDECAS 154
Query: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS--ISDP 2697
C GA C GY+CFC G G +C+ + SDP
Sbjct: 155 SPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDP 194
Score = 49.3 bits (116), Expect = 6e-05
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 2874 CDGT--ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLCIPD 2930
C+ T +CG N+C++GG C + C C +AG C C ++ C + ++C D
Sbjct: 107 CETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-QD 165
Query: 2931 QSFSYSCLCTLGWVGRYCE 2949
YSC C G+ GR+C+
Sbjct: 166 GIDGYSCFCVPGYQGRHCD 184
Score = 48.5 bits (114), Expect = 1e-04
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
+ D C + C+NG C +SC C+P + G C+ V C ++ C +++ C+ ++
Sbjct: 146 EIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCL-NE 204
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
Y+C+C + G CE
Sbjct: 205 IGRYTCICPHNYSGVNCE 222
Score = 48.5 bits (114), Expect = 1e-04
Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 40/174 (22%)
Query: 81 QIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTTEDQLLFGCRLKGMHTVNSKW 140
+I+ GD++ I P Q E+N F GC+Q+ +Q L
Sbjct: 823 KIEKGDVIYIGGLPDKQETELN-----GGFFKGCIQDVRLNNQNL--------------- 862
Query: 141 LSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFC--QESLSSEFCSGHGKCLSEAWSKTY 198
F + S P+ +NVT Q C S S C G C S W +
Sbjct: 863 ------EFFPNPTNNASLNPV--LVNVT---QGCAGDNSCKSNPCHNGGVCHSR-WDD-F 909
Query: 199 SCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKN 252
SC C SGK C+E+ C F PC + C Q +EC+ + F G++
Sbjct: 910 SCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVL-----QGFECIANAVFNGQS 958
Score = 48.5 bits (114), Expect = 1e-04
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 930 NECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYN 989
N C S PC N G C + F C+C G CE +V C SPC C G+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 990 CLCAPGYTGINCEI 1003
C+ + G + +I
Sbjct: 948 CIANAVFNGQSGQI 961
Score = 48.1 bits (113), Expect = 1e-04
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTD-IV 2395
C + C++ G C D C CP Y+G+ C+ C ++PC NGA C + G D
Sbjct: 114 CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC--QDGIDGYS 171
Query: 2396 CLCPYGRSGPLC 2407
C C G G C
Sbjct: 172 CFCVPGYQGRHC 183
Score = 47.8 bits (112), Expect = 2e-04
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 12/91 (13%)
Query: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCG--------- 2381
NC V C H C N TCIS C C ++GK C+ + + CG
Sbjct: 1210 NCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCY 1269
Query: 2382 NGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
NG C + T++ C+C G +G C I+
Sbjct: 1270 NGGNCT-EFQTELKCMCRPGFTGEWCEKDID 1299
Score = 47.4 bits (111), Expect = 2e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSG--KLCQFAS--CENNPCGNGATCVPKSG-TD 2393
C + C+NN TC +++ C C + K C C +NPC ATCV G
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
Query: 2394 IVCLCPYGRSGPLCTDAI 2411
+C CP G SG +C I
Sbjct: 94 FLCKCPPGYSGTICETTI 111
Score = 43.9 bits (102), Expect = 0.003
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 1044 NDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFT 1102
N C SNPC +G C +++ CSC A + C+ ++ C PC + CQ GF
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1103 CICPRGYTG 1111
CI + G
Sbjct: 948 CIANAVFNG 956
Score = 43.1 bits (100), Expect = 0.004
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
D + C + C+N C ++C C +++G C + C + CL+ + C D
Sbjct: 184 DLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC-QDA 242
Query: 2932 SFSYSCLCTLGWVGRYCENKT 2952
+Y C C G++G +CE T
Sbjct: 243 LGAYFCDCAPGFLGDHCELNT 263
Score = 42.4 bits (98), Expect = 0.007
Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 13/103 (12%)
Query: 858 NPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICR 917
NP N S LV+ Q C G N C C + G C ++F C C
Sbjct: 867 NPTNNASLNPVLVNVTQGCA------GDN------SCKSNPCHNGGVCHSRWDDFSCSCP 914
Query: 918 PGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHG 960
SG CE E+ C PC + C + F C ++G
Sbjct: 915 ALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVFNG 956
Score = 41.6 bits (96), Expect = 0.013
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 1006 DECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYP 1064
+ C S PC + GVC + ++C C + G CE C +PC HG +C ++ +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 1065 CSCDA--DGTSTQCKIKIN 1081
C +A +G S Q + N
Sbjct: 948 CIANAVFNGQSGQILFRSN 966
Score = 41.6 bits (96), Expect = 0.013
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 9/79 (11%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ----SVSC----LNNLCLHQSLCIPD 2930
C + C NG C + +SC C ++ G C Q S C N C + C
Sbjct: 1218 CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF 1277
Query: 2931 QSFSYSCLCTLGWVGRYCE 2949
Q+ C+C G+ G +CE
Sbjct: 1278 QT-ELKCMCRPGFTGEWCE 1295
Score = 41.2 bits (95), Expect = 0.016
Identities = 26/113 (23%), Positives = 35/113 (30%), Gaps = 45/113 (39%)
Query: 1081 NDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDG 1140
N C S PC N G C F+C CP +G CE+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------------------ 924
Query: 1141 PGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSG 1193
+ C SPC HGA C+ + G+ C ++G
Sbjct: 925 ---------------------VQWCGFSPCPHGAQCQPVLQGFECIANAVFNG 956
Score = 40.0 bits (92), Expect = 0.036
Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 9/83 (10%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDP--PHHCSRGATCISL 2671
C C N TC + C+C+ CD DP + C ATC++
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88
Query: 2672 P--HGYTCFCPLGTTGIYCEQAL 2692
P + C CP G +G CE +
Sbjct: 89 PGERSFLCKCPPGYSGTICETTI 111
Score = 40.0 bits (92), Expect = 0.036
Identities = 24/84 (28%), Positives = 31/84 (36%), Gaps = 10/84 (11%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C + PC N TC+ C C + G C + C + C G
Sbjct: 187 VDECASDPCK-----NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQ-----PCLNG 236
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
ATC Y C C G G +CE
Sbjct: 237 ATCQDALGAYFCDCAPGFLGDHCE 260
Score = 39.7 bits (91), Expect = 0.048
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 963
C S+PC++ G C++L + C+C Y GP C
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 39.7 bits (91), Expect = 0.048
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 722 NPGYVGIR--CEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP 779
NP V + C D + C N C + C + C C + G CE E C +P
Sbjct: 875 NPVLVNVTQGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
Query: 780 CKNNSTCTDLYKSYRCECTSGWTGQN 805
C + + C + + + C + + GQ+
Sbjct: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 39.3 bits (90), Expect = 0.062
Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 15/83 (18%)
Query: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNAC 742
+ C S+PC NG C + D FSC C G CE ++ C + C
Sbjct: 889 NSCKSNPCHNGGVCHSR--------------WDDFSCSCPALTSGKACE-EVQWCGFSPC 933
Query: 743 EHNSTCKDLHLSYQCVCLSDWEG 765
H + C+ + ++C+ + + G
Sbjct: 934 PHGAQCQPVLQGFECIANAVFNG 956
Score = 38.9 bits (89), Expect = 0.081
Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Query: 1163 NECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVH-ELCMENEPGSTC 1221
N C S+PC +G C + + C C SG CE C + C H C G C
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFEC 948
Query: 1222 LCTPGFMTCSIGLLC---GDEIRRITCLTPIFQRTD 1254
+ F S +L G+ R +T +T F+ D
Sbjct: 949 IANAVFNGQSGQILFRSNGNITRELTNITFGFRTRD 984
Score = 38.5 bits (88), Expect = 0.11
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 3/66 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
C N G C L C C ++G+ C+ C ++PC NG C CLC
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL-NKFQCLCDVA 1326
Query: 2402 RSGPLC 2407
+G C
Sbjct: 1327 FAGERC 1332
Score = 38.1 bits (87), Expect = 0.14
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 6/78 (7%)
Query: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC 270
C ++C PC N G C WD+ + C C +GK C E + C C HG
Sbjct: 885 CAGDNSCKSNPCHNGGVC---HSRWDD--FSCSCPALTSGKACEE-VQWCGFSPCPHGAQ 938
Query: 271 SNITSNSFICECDEQFSG 288
F C + F+G
Sbjct: 939 CQPVLQGFECIANAVFNG 956
Score = 35.8 bits (81), Expect = 0.69
Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 15/81 (18%)
Query: 647 CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQ 706
CKS C NG F C G CE ++ C PC +GA C QP
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQC--QP------ 941
Query: 707 CVPPFKVVDGFSCLCNPGYVG 727
V+ GF C+ N + G
Sbjct: 942 ------VLQGFECIANAVFNG 956
Score = 34.3 bits (77), Expect = 2.0
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C D C NGG C + + FQC C + F G CE D
Sbjct: 1301 CASDPCVNGGLCQDL-----LNKFQCLCDVAFAGERCEVD 1335
Score = 33.9 bits (76), Expect = 2.6
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C ++ C +GG CH + C CP + GRFCE D
Sbjct: 114 CGKNSCQHGGICH-----QDPIYPVCICPAGYAGRFCEID 148
Score = 33.1 bits (74), Expect = 4.4
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 1039
+ D C S+PC G CI+ Y CDC + G +C
Sbjct: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 274 bits (700), Expect = 1e-72
Identities = 136/355 (38%), Positives = 189/355 (53%), Gaps = 39/355 (10%)
Query: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK 971
FRC C PGF G CE++I+EC+S PC + TC +L +R+ C+C Y G CE++V++C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 972 ISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCK 1031
+PCL +C+ + C+CAPGY G C+++LDEC S+PC H G C D +N + CDC
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 1032 -SGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCM 1089
+G+ GTHCE +C S PC H C E + + C C + C++ ++C S PC
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
Query: 1090 NEGFC-QKS--------------------AHGFTCICPRGYTGAYCEKSIDNCAEPELNS 1128
+ G C Q+S A GF C CP G+ GA C +D CA S
Sbjct: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECA-----S 326
Query: 1129 VICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQ 1188
CLNGG C D P + F C C G++G CE +++EC S PCLHG C D + GY+C+C
Sbjct: 327 RPCLNGGHCQDLP-NGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCP 385
Query: 1189 PGWSGHHCENELE-CIPNSC-VHELCM----ENEPGSTCLCTPGFMTCSIGLLCG 1237
W G C +L C ++C + C+ C C PG + G CG
Sbjct: 386 ETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPG----THGPFCG 436
Score = 259 bits (663), Expect = 2e-68
Identities = 138/402 (34%), Positives = 182/402 (45%), Gaps = 49/402 (12%)
Query: 685 CASHPCKNGATC-IDQPGNYFCQ-----------------CVPPFKVVDGFSCLCNPGYV 726
CAS PC G C + G Y C CVP GF C C PG+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
Query: 727 GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTC 786
G RCE DID+C C H +TC++L Y+C C + G CE E +EC PC + +C
Sbjct: 102 GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSC 161
Query: 787 TDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPL-YTGQF 845
D S+RC C G+ G C +++EC S PC +GG CH+ + F C C Y G
Sbjct: 162 LDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHD--LVNGFRCDCAGTGYEGTH 219
Query: 846 CHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDC 905
C + C PC +N++CL + + C+C + G+ CE+D +C CQ G C
Sbjct: 220 CEREVLEC--ASAPCEHNASCLEGL-GSFRCLCWPGYSGELCEVDEDECASSPCQHGGRC 276
Query: 906 EDMVN---------------------NFRCICRPGFSGSLCEIEINECSSEPCKNNGTCV 944
+ F C C PGF G+ C +E++EC+S PC N G C
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ 336
Query: 945 DLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEIN 1004
DL N F C+C Y GP CE DV++C PCL C GY C C + G +C +
Sbjct: 337 DLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQ 396
Query: 1005 LDECLSEPCLHDGVCI----DGINHYTCDCKSGFFGTHCETN 1042
L C C CI G++ Y C C G G C N
Sbjct: 397 LTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Score = 251 bits (641), Expect = 8e-66
Identities = 136/430 (31%), Positives = 194/430 (45%), Gaps = 46/430 (10%)
Query: 760 LSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSE-EINECDSDPC 818
LS G + + C +PC + C SG G C E C + PC
Sbjct: 27 LSLLAGTVPSEPPSACASDPCAPGTECQ--------ATESG--GYTCGPMEPRGCATQPC 76
Query: 819 MNGGLC-HESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCI 877
+G LC + P F C C P + G C + C PC + +TC L D + C
Sbjct: 77 HHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDEC--ASRPCHHGATCRNLADRYE-CH 133
Query: 878 CREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
C + G CE++V +C C G C D V +FRC+C PG+ G+ C+++++EC S+PC
Sbjct: 134 CPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPC 193
Query: 938 KNNGTCVDLTNRFFCNCEPE-YHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY 996
+ GTC DL N F C+C Y G CE +V +C +PC +C+ + CLC PGY
Sbjct: 194 AHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY 253
Query: 997 TGINCEINLDECLSEPCLHDGVCID------------------GINH---YTCDCKSGFF 1035
+G CE++ DEC S PC H G C+ H + C C GF
Sbjct: 254 SGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 1036 GTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFC 1094
G C ++C S PCL+G C +L N + C C C+ +++C S PC++ G C
Sbjct: 314 GADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC 373
Query: 1095 QKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICV---DGPGHTFDCRCLP 1151
+ G+ C CP + G C + C C C+ + H++ C C P
Sbjct: 374 SDTVAGYICRCPETWGGRDCSVQLTGC-----QGHTCPLAATCIPIFESGVHSYVCHCPP 428
Query: 1152 GFSGQFCEIN 1161
G G FC N
Sbjct: 429 GTHGPFCGQN 438
Score = 235 bits (599), Expect = 6e-61
Identities = 116/348 (33%), Positives = 170/348 (48%), Gaps = 41/348 (11%)
Query: 640 CEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699
CE+D ++C S C +G T +L + C G+ G CE+++DECAS PC +G +C+D
Sbjct: 105 CELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDG 164
Query: 700 PGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVC 759
G+ F C+C PGY G RC+ D+D+C C H TC DL ++C C
Sbjct: 165 VGS--------------FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
Query: 760 L-SDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC 818
+ +EG CE+E EC PC++N++C + S+RC C G++G+ C + +EC S PC
Sbjct: 211 AGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPC 270
Query: 819 MNGGLCHESTIP-------------------GQFVCLCPPLYTGQFCHQRYNLCDLLHNP 859
+GG C + + P F+C CPP + G C + C P
Sbjct: 271 QHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC--ASRP 328
Query: 860 CRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPG 919
C N C L + Q C C + + G CE DV +CL C G C D V + C C
Sbjct: 329 CLNGGHCQDLPNGFQ-CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPET 387
Query: 920 FSGSLCEIEINECSSEPCKNNGTCVDL----TNRFFCNCEPEYHGPFC 963
+ G C +++ C C TC+ + + + C+C P HGPFC
Sbjct: 388 WGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 211 bits (538), Expect = 7e-54
Identities = 120/381 (31%), Positives = 178/381 (46%), Gaps = 51/381 (13%)
Query: 575 CQHEAVCKDEINRP---RCSCSLSYIGRLCVVNVDYCLGNHSISVHGL-CLALSHNCNCS 630
C H A+C + P RC C + G C +++D C HG C L+ C
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCH--HGATCRNLADRYECH 133
Query: 631 GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPC 690
Y CE++ ++C SA C +G + G F C PG+ GT+C++D+DEC S PC
Sbjct: 134 CPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPC 193
Query: 691 KNGATCIDQPGNYFCQCVPPFKVVDGFSCLC-NPGYVGIRCEQDIDDCILNACEHNSTCK 749
+G TC D +V+GF C C GY G CE+++ +C CEHN++C
Sbjct: 194 AHGGTCHD--------------LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCL 239
Query: 750 DLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTD-----LY-------------- 790
+ S++C+C + G CE + +EC +PC++ C LY
Sbjct: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFR 299
Query: 791 --KSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQ 848
+ C C G+ G +C E++EC S PC+NGG C + +P F C CP Y G C +
Sbjct: 300 HAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD--LPNGFQCHCPDGYAGPTCEE 357
Query: 849 RYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDC--- 905
+ C L +PC + TC V A C C E + G++C + + C +C C
Sbjct: 358 DVDEC--LSDPCLHGGTCSDTV-AGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPI 414
Query: 906 -EDMVNNFRCICRPGFSGSLC 925
E V+++ C C PG G C
Sbjct: 415 FESGVHSYVCHCPPGTHGPFC 435
Score = 201 bits (510), Expect = 1e-50
Identities = 111/359 (30%), Positives = 159/359 (44%), Gaps = 57/359 (15%)
Query: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYR---TDGY 988
C+S+PC C T C P ++ C PC CV + G+
Sbjct: 42 CASDPCAPGTEC-QATESGGYTCGP--------MEPRGCATQPCHHGALCVPQGPDPTGF 92
Query: 989 NCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLS 1048
C C PG+ G CE+++DEC S PC H C + + Y C C G+ G CE ++C S
Sbjct: 93 RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS 152
Query: 1049 NPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICP- 1106
PCLH G C + + + C C T+C++ +++C S PC + G C +GF C C
Sbjct: 153 APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAG 212
Query: 1107 RGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECS 1166
GY G +CE+ + CA S C + C++G G +F C C PG+SG+ CE++ +EC+
Sbjct: 213 TGYEGTHCEREVLECA-----SAPCEHNASCLEGLG-SFRCLCWPGYSGELCEVDEDECA 266
Query: 1167 SSPCLHGADCED---------------------HINGYVCKCQPGWSGHHCENEL-ECIP 1204
SSPC HG C H G++C C PG+ G C E+ EC
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 1205 NSCVH-ELCMENEPGSTCLCTPGFM--------------TCSIGLLCGDEIRRITCLTP 1248
C++ C + G C C G+ C G C D + C P
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCP 385
Score = 190 bits (483), Expect = 2e-47
Identities = 111/379 (29%), Positives = 167/379 (44%), Gaps = 45/379 (11%)
Query: 535 CANGCSCLSE-EDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCS 593
C +G C+ + D +R C + G + + C H A C++ +R C C
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCP 135
Query: 594 LSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCK 653
L Y G C + VD C + G CL + C Y C++D ++C+S C
Sbjct: 136 LGYAGVTCEMEVDECASAPCLH-GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCA 194
Query: 654 NGTTSTHLRGYFFRKCV-PGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFK 712
+G T L F C G++GT CE ++ ECAS PC++ A+C++ G+
Sbjct: 195 HGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS---------- 244
Query: 713 VVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLH-------------------- 752
F CLC PGY G CE D D+C + C+H C
Sbjct: 245 ----FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRH 300
Query: 753 -LSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEIN 811
+ C C +EG C E +EC PC N C DL ++C C G+ G C E+++
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD 360
Query: 812 ECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVD 871
EC SDPC++GG C + T+ G ++C CP + G+ C + C + C +TC+ + +
Sbjct: 361 ECLSDPCLHGGTCSD-TVAG-YICRCPETWGGRDCSVQLTGCQ--GHTCPLAATCIPIFE 416
Query: 872 ANQH---CICREEFEGKNC 887
+ H C C G C
Sbjct: 417 SGVHSYVCHCPPGTHGPFC 435
Score = 185 bits (470), Expect = 5e-46
Identities = 106/337 (31%), Positives = 152/337 (45%), Gaps = 17/337 (5%)
Query: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
C +G +C + D Y C L +AG + C H C D + RC C+
Sbjct: 117 CHHGATCRNLAD--RYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAP 174
Query: 595 SYIGRLCVVNVDYCLGN---HSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSAS 651
Y G C +++D C H + H L C+C+G YE CE + +C SA
Sbjct: 175 GYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF--RCDCAGTG-YEGTHCEREVLECASAP 231
Query: 652 CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ--PGNYF-CQCV 708
C++ + G F C PG+ G CE+D DECAS PC++G C+ + P Y Q
Sbjct: 232 CEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAA 291
Query: 709 PP----FKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWE 764
P F+ GF C C PG+ G C ++D+C C + C+DL +QC C +
Sbjct: 292 FPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYA 351
Query: 765 GNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLC 824
G CE++ +EC +PC + TC+D Y C C W G++CS ++ C C C
Sbjct: 352 GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
Query: 825 HESTIPG--QFVCLCPPLYTGQFCHQRYNLCDLLHNP 859
G +VC CPP G FC Q + +P
Sbjct: 412 IPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSP 448
Score = 121 bits (303), Expect = 1e-26
Identities = 81/310 (26%), Positives = 119/310 (38%), Gaps = 47/310 (15%)
Query: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Y CHC ++G C+ E+D C+ PC + GSC++ ++ CVC P + G C
Sbjct: 130 YECHCPLGYAGVTCEMEVDECASAPCLHGGSCLD-----GVGSFRCVCAPGYGGTRCQLD 184
Query: 257 IGQCQPHVCFHGNCSNITSNSFICEC-DEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSA 315
+ +CQ C HG + N F C+C + G CE C S C +
Sbjct: 185 LDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS 244
Query: 316 YTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDV--------------------- 354
+ C G S + E D E + PCQ+G C++ S+
Sbjct: 245 FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGF 304
Query: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKL 414
+C C P F C C S P N C+ + C C G+ CE+ +D C
Sbjct: 305 LCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDEC-- 362
Query: 415 LSINCLNEEWCFNII------------GRFKYVCIPGCTKNPCWFLKNVYLI-----HQH 457
LS CL+ C + + GR V + GC + C I H +
Sbjct: 363 LSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSY 422
Query: 458 LCYCGVTFHG 467
+C+C HG
Sbjct: 423 VCHCPPGTHG 432
Score = 110 bits (275), Expect = 2e-23
Identities = 103/445 (23%), Positives = 153/445 (34%), Gaps = 90/445 (20%)
Query: 216 ACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC---SN 272
AC+ PC C + + Y C P + C+ QP C HG
Sbjct: 41 ACASDPCAPGTEC----QATESGGYTC---GPMEPRGCAT-----QP--CHHGALCVPQG 86
Query: 273 ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETD 332
F C C F GP CE+ C S C N + Y CP G + E +
Sbjct: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Query: 333 VSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDY 392
V E + PC +G C+ C+C+P + C+ C+S P + TC +
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 393 PCSCI-SGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG------------ 439
C C +G+ +CE+ + C S C + C +G F+ +C PG
Sbjct: 207 RCDCAGTGYEGTHCEREVLEC--ASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDE 264
Query: 440 CTKNPCWFLKNVYLIHQHLCYC----GVTFHGICQDKGPAQFEYVWQLGF-----AGSEG 490
C +PC QH C +G Q P F + GF G EG
Sbjct: 265 CASSPC----------QHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG 314
Query: 491 EKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEY 550
C +D E C NG C ++ +
Sbjct: 315 ADCGVEVD------------------------------ECASRPCLNGGHC--QDLPNGF 342
Query: 551 RYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLG 610
+ C +AG E+ + + C H C D + C C ++ GR C V + C G
Sbjct: 343 QCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQG 402
Query: 611 NHSISVHGLCLAL------SHNCNC 629
H+ + C+ + S+ C+C
Sbjct: 403 -HTCPLAATCIPIFESGVHSYVCHC 426
Score = 99.8 bits (247), Expect = 4e-20
Identities = 50/150 (33%), Positives = 65/150 (43%), Gaps = 3/150 (2%)
Query: 894 CLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCN 953
C C G C D+ + F C C PG+ G CE ++ C S PC RF C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 954 CEPEYHGPFCELDV--NKCKIS-PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLS 1010
C P + GP C L V +C ++ CLD C + NC C G G C++ C +
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 1011 EPCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
PCL+ G C C C + F G CE
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 99.4 bits (246), Expect = 5e-20
Identities = 53/157 (33%), Positives = 74/157 (47%), Gaps = 10/157 (6%)
Query: 1008 CLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRC-TELINEYPCS 1066
C PCLHDG C D + + C C G+ G CE + + C S PC GRC T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1067 CDADGTSTQCKIKI--NDCT-SIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAE 1123
C +C++ + +C+ ++ C++ C+ + C C G G C+ C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC-- 1177
Query: 1124 PELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEI 1160
E N CLNGG C G +C C FSGQFCE+
Sbjct: 1178 -EANP--CLNGGTC-RAAGGVSECICNARFSGQFCEV 1210
Score = 98.6 bits (244), Expect = 9e-20
Identities = 53/154 (34%), Positives = 75/154 (48%), Gaps = 6/154 (3%)
Query: 1046 CLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHG-FTC 1103
C +PCLH G C +L + + C+C +C+ ++ C S PC G C G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
Query: 1104 ICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININ 1163
CP G+ G C + + E LN V CL+G C +G +C CL G +GQ C++
Sbjct: 1119 RCPPGFGGPRCRLPVPS-KECSLN-VTCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPTL 1175
Query: 1164 ECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE 1197
C ++PCL+G C C C +SG CE
Sbjct: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 94.7 bits (234), Expect = 1e-18
Identities = 51/152 (33%), Positives = 70/152 (46%), Gaps = 6/152 (3%)
Query: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG-YNC 990
C+ PC ++G C DL + F C C P + GP CE V+ C +PC C DG + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA-RGRCHTHPDGRFEC 1118
Query: 991 LCAPGYTGINCEINL--DEC-LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCL 1047
C PG+ G C + + EC L+ CL C G C C G G C+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 1048 SNPCLH-GRCTELINEYPCSCDADGTSTQCKI 1078
+NPCL+ G C C C+A + C++
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 94.4 bits (233), Expect = 2e-18
Identities = 49/160 (30%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
C +PC ++ C DL+ ++ C C GW G C ++ C S PC G CH G+F
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHP-DGRFE 1117
Query: 835 CLCPPLYTGQFCHQ-------RYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
C CPP + G C N+ L +PC S +C C E G+ C
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAA-------NCSCLEGLAGQRC 1170
Query: 888 EIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEI 927
++ C C + G C CIC FSG CE+
Sbjct: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 82.8 bits (203), Expect = 5e-15
Identities = 47/156 (30%), Positives = 65/156 (41%), Gaps = 8/156 (5%)
Query: 737 CILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCE 796
C + C H+ C+DL ++ C C WEG CE + C PC T + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 797 CTSGWTGQNCSEEI--NECDSD-PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC 853
C G+ G C + EC + C++G C + C C GQ C C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN--CSCLEGLAGQRCQVPTLPC 1177
Query: 854 DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEI 889
+ NPC N TC A ++ CIC F G+ CE+
Sbjct: 1178 EA--NPCLNGGTCRAAGGVSE-CICNARFSGQFCEV 1210
Score = 82.4 bits (202), Expect = 6e-15
Identities = 51/164 (31%), Positives = 68/164 (41%), Gaps = 19/164 (11%)
Query: 647 CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQ 706
C + C + L F C PG++G +CE +D C S PC G C P
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHP------ 1112
Query: 707 CVPPFKVVDG-FSCLCNPGYVGIRCEQDI--DDCILN-ACEHNSTCKDLHLSYQCVCLSD 762
DG F C C PG+ G RC + +C LN C S C+ + C CL
Sbjct: 1113 --------DGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG 1164
Query: 763 WEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC 806
G C+ + C+ NPC N TC C C + ++GQ C
Sbjct: 1165 LAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 75.5 bits (184), Expect = 8e-13
Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 11/152 (7%)
Query: 618 GLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQ 677
G C L C+ +E CE + C SA C G TH G F +C PGF G +
Sbjct: 1069 GACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPR 1128
Query: 678 CEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDC 737
C + + S C TC+D C+ P +C C G G RC+ C
Sbjct: 1129 CRLPV---PSKECSLNVTCLDGSP---CEGGSP-----AANCSCLEGLAGQRCQVPTLPC 1177
Query: 738 ILNACEHNSTCKDLHLSYQCVCLSDWEGNFCE 769
N C + TC+ +C+C + + G FCE
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 74.7 bits (182), Expect = 1e-12
Identities = 44/161 (27%), Positives = 64/161 (39%), Gaps = 8/161 (4%)
Query: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC 270
C+ C+ PC ++G+C R+ +D A+ C C P + G C + C C G C
Sbjct: 1054 CRGAPVCAPSPCLHDGAC---RDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRC 1108
Query: 271 SNITSNSFICECDEQFSGPFCE--VSAKPC-VSLLFWKRGICPNSSSAYTYECPKGSSSQ 327
F C C F GP C V +K C +++ C S A C +G + Q
Sbjct: 1109 HTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
Query: 328 NGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCK 368
+ PC NG C CIC+ F+ C+
Sbjct: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 72.0 bits (175), Expect = 9e-12
Identities = 79/342 (23%), Positives = 129/342 (37%), Gaps = 45/342 (13%)
Query: 2588 GHFRGLGN------PEGH--PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTG 2639
GH + L N P+G+ P V +C + PC +GGTC ++ C C
Sbjct: 333 GHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCL-----HGGTCSDTVAGYICRCPET 387
Query: 2640 WKGSFCTETVSTCDPEHDPPHHCSRGATCISL----PHGYTCFCPLGTTGIYCEQALSIS 2695
W G C+ ++ C H C ATCI + H Y C CP GT G +C Q + S
Sbjct: 388 WGGRDCSVQLTGCQ-----GHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFS 442
Query: 2696 DPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNS 2755
+ + AS + L+F+ G L + + + L ++LV +
Sbjct: 443 VMAGSPIQ------ASVPAGGPLGLALRFRTTLPAGTL-----ATRNDTKESLELALVAA 491
Query: 2756 SVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSL 2815
++Q T+++ L + +N WH +V +L + + + +
Sbjct: 492 TLQATLWSYSTTVLVLRLPDLALNDGHWH-----QVEVVLHLATLELRLWHEGCPARLCV 546
Query: 2816 DTNTDFYIGGVSSLNLVNPMAIENEPVG---FQGCIRQVIINNQELQLTEFGAKGGSNVG 2872
+ S+ L P I + +G F GC++ V ++ L + G +G
Sbjct: 547 ASGPVALASTASATPL--PAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGE--NVLLG 602
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV 2914
C C +GG C T F C C G TC +
Sbjct: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 61.6 bits (148), Expect = 1e-08
Identities = 78/347 (22%), Positives = 117/347 (33%), Gaps = 65/347 (18%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK--DAGLFFPSFNGNSYLELPF 2160
C CH+G TC + ++C CPL + G CE D P +G S L+
Sbjct: 112 CASRPCHHGATCRNL-----ADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLD--- 163
Query: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQ----------FLHLFLVEGRP 2210
V + + GT + + C Q ++ F +
Sbjct: 164 -----------GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAG 212
Query: 2211 SVKYGCGNSQNILT-VSANYSINTNAFTPI-TIRYTTPVGSPGVVCMIEMTADGKPP--- 2265
+ G + +L SA N + + + R G G +C ++ P
Sbjct: 213 TGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQH 272
Query: 2266 ----VQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFI 2321
+Q+ D + QA F F A H G F G ++V+
Sbjct: 273 GGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPG----FEGADCGVEVDECASRP 328
Query: 2322 IDEARHGKNIEN---CHVP-------------WCAHHLCRNNGTCISDNENLFCECPRLY 2365
H +++ N CH P C C + GTC C CP +
Sbjct: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETW 388
Query: 2366 SGKLC--QFASCENNPCGNGATCVP--KSGT-DIVCLCPYGRSGPLC 2407
G+ C Q C+ + C ATC+P +SG VC CP G GP C
Sbjct: 389 GGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 59.3 bits (142), Expect = 6e-08
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 8/92 (8%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESG---TSVYCNCTTGWKGSFCTETVSTCDPEHD 2657
+ G + G C+ C +G C+ G T C C G++G C + C
Sbjct: 58 SGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASR-- 115
Query: 2658 PPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
P HH GATC +L Y C CPLG G+ CE
Sbjct: 116 PCHH---GATCRNLADRYECHCPLGYAGVTCE 144
Score = 58.5 bits (140), Expect = 1e-07
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 13/87 (14%)
Query: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE-CIPNSCVHELCMENEPGS-TCL 1222
C+ SPCLH C D + + C C PGW G CE ++ C C C + G C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1223 CTPGF-----------MTCSIGLLCGD 1238
C PGF CS+ + C D
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLD 1146
Score = 58.2 bits (139), Expect = 1e-07
Identities = 101/474 (21%), Positives = 165/474 (34%), Gaps = 87/474 (18%)
Query: 2519 FFQEGWLKVDDHKNKSIIAPGR-------LVGLN--------VFSQFYVGGYSEYTPDLL 2563
F EG ++ + + +++ PGR LV L+ + +VGG D
Sbjct: 699 FLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRL-LAADSQ 757
Query: 2564 PNGADFKNGFQ-----GC---IFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCS 2615
P G F+ Q GC F L + G G + + G CS
Sbjct: 758 PWGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELG-----GRQSWNLTAGCVSEDMCS 812
Query: 2616 LMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGY 2675
C NGGTC+ + +C C + G C + + P C ATC +P G+
Sbjct: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWC------PGQPCLPPATCEEVPDGF 866
Query: 2676 TCFCPLGTTGIYCEQALSISDPSFRSN-ELSWMSFASFHVRKKTHIQLQFQPLAADGILF 2734
C +++ +FR ++ + R + L F+ ++ L
Sbjct: 867 VC----------------VAEATFREGPPAAFSGHNASSGRLLGGLSLAFRTRDSEAWLL 910
Query: 2735 YAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHII-----KAG 2789
AA A G +L + + + +R G +L +G+ WH + +
Sbjct: 911 RAA--AGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPGPRVADGA-WHRVRLAMERPA 967
Query: 2790 RVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIR 2849
+ L LDG A+T ++ +D +G + V + EN F GC+
Sbjct: 968 ATTSRWLLWLDG------AATPVALRGLASD--LGFLQGPGAVRILLAEN----FTGCLG 1015
Query: 2850 QVIINNQELQLT--EFGAKGGSN------------VGDCDGT-ACGYNTCRNGGECTVNG 2894
+V + L L GA G+ + C G C + C + G C
Sbjct: 1016 RVALGGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLF 1075
Query: 2895 TTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
F+C C P W G C V ++ + C + C C G+ G C
Sbjct: 1076 DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRC 1129
Score = 55.8 bits (133), Expect = 6e-07
Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C C NGG C F C C +AG TC + V CL++ CLH C D Y C
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC-SDTVAGYIC 382
Query: 2938 LCTLGWVGRYC 2948
C W GR C
Sbjct: 383 RCPETWGGRDC 393
Score = 53.5 bits (127), Expect = 3e-06
Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 16/180 (8%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLCIP---D 2930
D C + C +GG C+ + CRC W G C+ Q C + C + CIP
Sbjct: 358 DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFES 417
Query: 2931 QSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTK 2990
SY C C G G +C T+FS M S I+ P L +L F TT
Sbjct: 418 GVHSYVCHCPPGTHGPFCGQNTTFSV---MAGSPIQASVPAGGPLGL-----ALRFRTTL 469
Query: 2991 TEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVI 3050
G + +N+ + L + L TL+ + + + + WH V V+
Sbjct: 470 PAGTLA----TRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVV 525
Score = 52.0 bits (123), Expect = 9e-06
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 2857 ELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNG---TTFSCRCLPDWAGNTCNQS 2913
E Q TE GG G + C C +G C G T F C C+P + G C
Sbjct: 52 ECQATE---SGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELD 108
Query: 2914 VS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+ C + C H + C + + Y C C LG+ G CE
Sbjct: 109 IDECASRPCHHGATC-RNLADRYECHCPLGYAGVTCE 144
Score = 51.2 bits (121), Expect = 2e-05
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCL 991
CS +PC N GTC+ N F C C + GP C + C PCL C DG+ C+
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Score = 50.4 bits (119), Expect = 3e-05
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 11/86 (12%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C ++PC +GG+C++ S C C G+ G+ C + C + C+ G
Sbjct: 147 VDECASAPCL-----HGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ-----PCAHG 196
Query: 2666 ATCISLPHGYTCFCP-LGTTGIYCEQ 2690
TC L +G+ C C G G +CE+
Sbjct: 197 GTCHDLVNGFRCDCAGTGYEGTHCER 222
Score = 50.4 bits (119), Expect = 3e-05
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
C +PC N TC + + C C + +TG C++++ C PC+ C E +P FV
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEE--VPDGFV 867
Query: 835 CL 836
C+
Sbjct: 868 CV 869
Score = 50.1 bits (118), Expect = 4e-05
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
Query: 198 YSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE-NWDEQAYECVCHPPFTGKNCSEI 256
+ C C P F G C+ L S K C N +C++ A C C G+ C
Sbjct: 1116 FECRCPPGFGGPRCR-LPVPS-KECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP 1173
Query: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
C+ + C +G C C+ +FSG FCEV+
Sbjct: 1174 TLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVA 1211
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
+ D C C +G C + C C +AG TC V C + CLH C+ D
Sbjct: 106 ELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCL-DG 164
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
S+ C+C G+ G C+
Sbjct: 165 VGSFRCVCAPGYGGTRCQ 182
Score = 47.0 bits (110), Expect = 3e-04
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCT-TGWKGSFCTETVSTCDPEHDP 2658
P G + Q C C +GGTC + C+C TG++G+ C V C
Sbjct: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC-----A 228
Query: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
C A+C+ + C C G +G CE
Sbjct: 229 SAPCEHNASCLEGLGSFRCLCWPGYSGELCE 259
Score = 43.5 bits (101), Expect = 0.003
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
CA C N G C C CP Y+G C+ C ++PC +G TC + +C
Sbjct: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC-SDTVAGYIC 382
Query: 2397 LCPYGRSGPLCT 2408
CP G C+
Sbjct: 383 RCPETWGGRDCS 394
Score = 42.0 bits (97), Expect = 0.010
Identities = 69/309 (22%), Positives = 106/309 (34%), Gaps = 83/309 (26%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLK 2162
C+ C +GG+C ++ F+CDC G C + G
Sbjct: 609 CRPLPCVHGGSCVDLW-----THFRCDCARPHRGPTCADEIPAATFGLGGAP----SSAS 659
Query: 2163 FVLEKEHNRTVTIYLTIKTNSLNGTIL-YSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQN 2221
F+L++ +T+ ++T G +L ++N + G L +FL EGR
Sbjct: 660 FLLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAG---LTVFLSEGR------------ 704
Query: 2222 ILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYF 2281
IR P GSP VV + D + H F
Sbjct: 705 -------------------IRAEVP-GSPAVVLP-----------GRWDDGLRHLVMLSF 733
Query: 2282 ESMFLGHIPANVQIHKK---------AGPVYGFRGCILDLQVN--NKEFFIIDEARHGKN 2330
L + +V + + GP FRGC+ DL+++ + FF + +
Sbjct: 734 GPDQLQDLGQHVHVGGRLLAADSQPWGGP---FRGCLQDLRLDGCHLPFFPLPLDNSSQP 790
Query: 2331 IE-NCHVPW-----------CAHHLCRNNGTCISDNENLFCECPRLYSGKLC-QFASCEN 2377
E W C+ C N GTC+ + C CP ++G C Q C
Sbjct: 791 SELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPG 850
Query: 2378 NPCGNGATC 2386
PC ATC
Sbjct: 851 QPCLPPATC 859
Score = 42.0 bits (97), Expect = 0.010
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVCLCPYG 2401
C + C + C C +G+ CQ + CE NPC NG TC G C+C
Sbjct: 1144 CLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS-ECICNAR 1202
Query: 2402 RSGPLCTDAINITQP 2416
SG C A + P
Sbjct: 1203 FSGQFCEVAKGLPLP 1217
Score = 41.6 bits (96), Expect = 0.013
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C C +GG C +F C C P + G C + C + C H C D + C
Sbjct: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC-HDLVNGFRC 208
Query: 2938 LCT-LGWVGRYCENK 2951
C G+ G +CE +
Sbjct: 209 DCAGTGYEGTHCERE 223
Score = 41.6 bits (96), Expect = 0.013
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
Query: 2879 CGYN-TCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLCIPDQSFSYS 2936
C N TC +G C +C CL AG C ++ C N CL+ C S
Sbjct: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS-E 1196
Query: 2937 CLCTLGWVGRYCE 2949
C+C + G++CE
Sbjct: 1197 CICNARFSGQFCE 1209
Score = 41.2 bits (95), Expect = 0.016
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 2879 CGYNTCRNGGEC--TVNGTTFSCRCL-PDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFS 2934
C C +GG C VNG F C C + G C + V C + C H + C+ S
Sbjct: 188 CQSQPCAHGGTCHDLVNG--FRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG-S 244
Query: 2935 YSCLCTLGWVGRYCE 2949
+ CLC G+ G CE
Sbjct: 245 FRCLCWPGYSGELCE 259
Score = 40.8 bits (94), Expect = 0.021
Identities = 15/43 (34%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 768 CEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEI 810
CE+ +C+ PC + +C DL+ +RC+C G C++EI
Sbjct: 603 CERRE-QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 40.4 bits (93), Expect = 0.028
Identities = 20/76 (26%), Positives = 28/76 (36%), Gaps = 5/76 (6%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C+ C +G TC C+C G+ G C V C C G +C+
Sbjct: 112 CASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC-----ASAPCLHGGSCLDGVG 166
Query: 2674 GYTCFCPLGTTGIYCE 2689
+ C C G G C+
Sbjct: 167 SFRCVCAPGYGGTRCQ 182
Score = 40.4 bits (93), Expect = 0.028
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 7/80 (8%)
Query: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC 270
C D CS PC N G+C+ W++ + C C FTG C++ + C C
Sbjct: 805 CVSEDMCSPDPCFNGGTCL---VTWND--FHCTCPANFTGPTCAQQL-WCPGQPCLPPAT 858
Query: 271 SNITSNSFICECDEQF-SGP 289
+ F+C + F GP
Sbjct: 859 CEEVPDGFVCVAEATFREGP 878
Score = 40.4 bits (93), Expect = 0.028
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCL-HGRCTELIN 1061
++ D C +PC + G C+ N + C C + F G C C PCL C E+ +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 1062 EYPCSCDA 1069
+ C +A
Sbjct: 865 GFVCVAEA 872
Score = 40.4 bits (93), Expect = 0.028
Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 1046 CLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCI 1104
C +PC +G C N++ C+C A+ T C ++ C PC+ C++ GF C+
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Score = 40.0 bits (92), Expect = 0.036
Identities = 36/158 (22%), Positives = 48/158 (30%), Gaps = 61/158 (38%)
Query: 2604 RSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTC----------- 2652
R V +C ++PC + +C+E S C C G+ G C C
Sbjct: 222 REVLECASAPCE-----HNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRC 276
Query: 2653 ----DPE-----------------------HDPP----------------HHCSRGATCI 2669
DP H PP C G C
Sbjct: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ 336
Query: 2670 SLPHGYTCFCPLGTTGIYCEQALS--ISDPSFRSNELS 2705
LP+G+ C CP G G CE+ + +SDP S
Sbjct: 337 DLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCS 374
Score = 39.7 bits (91), Expect = 0.048
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 11/93 (11%)
Query: 779 PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCP 838
P N+S ++L T+G ++ C DPC NGG C + F C CP
Sbjct: 783 PLDNSSQPSELGGRQSWNLTAGCVSEDM------CSPDPCFNGGTCLVTW--NDFHCTCP 834
Query: 839 PLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVD 871
+TG C Q+ C PC +TC + D
Sbjct: 835 ANFTGPTCAQQL-WCP--GQPCLPPATCEEVPD 864
Score = 39.7 bits (91), Expect = 0.048
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 899 CQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEY 958
C + G C N+F C C F+G C ++ C +PC TC ++ + F C E +
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
Query: 959 -HGP 961
GP
Sbjct: 875 REGP 878
Score = 39.7 bits (91), Expect = 0.048
Identities = 21/46 (45%), Positives = 27/46 (58%), Gaps = 5/46 (10%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFP 2148
C+ + C NGGTC A +G VS +C C F+G+FCE GL P
Sbjct: 1177 CEANPCLNGGTCRA----AGGVS-ECICNARFSGQFCEVAKGLPLP 1217
Score = 39.3 bits (90), Expect = 0.062
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 970 CKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCD 1029
C PC + C+ + ++C C +TG C L C +PCL C + + + C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 1030 CKSGF 1034
++ F
Sbjct: 870 AEATF 874
Score = 38.9 bits (89), Expect = 0.081
Identities = 23/97 (23%), Positives = 35/97 (36%), Gaps = 24/97 (24%)
Query: 2339 CAHHLCRNNGTCISDNE---------------------NLFCECPRLYSGKLC--QFASC 2375
CA C++ G C+ ++ C CP + G C + C
Sbjct: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
Query: 2376 ENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
+ PC NG C C CP G +GP C + ++
Sbjct: 325 ASRPCLNGGHCQDLPN-GFQCHCPDGYAGPTCEEDVD 360
Score = 38.9 bits (89), Expect = 0.081
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 931 ECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 963
+C PC + G+CVDL F C+C + GP C
Sbjct: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 38.9 bits (89), Expect = 0.081
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 1083 CTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVIC---LNGGICV 1138
C+ PC N G C + + F C CP +TG C + + +P L C +G +CV
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCV 869
Score = 38.5 bits (88), Expect = 0.11
Identities = 19/64 (29%), Positives = 26/64 (40%), Gaps = 1/64 (1%)
Query: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEP-GSTCLC 1223
CS PC +G C N + C C ++G C +L C C+ E P G C+
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCVA 870
Query: 1224 TPGF 1227
F
Sbjct: 871 EATF 874
Score = 38.1 bits (87), Expect = 0.14
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 7/60 (11%)
Query: 984 RTDGYNCLCAPGYTGIN----CEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 1039
R DG+ L P G N CE ++C PC+H G C+D H+ CDC G C
Sbjct: 584 RVDGH--LLLPEDLGENVLLGCE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 38.1 bits (87), Expect = 0.14
Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 3/73 (4%)
Query: 2337 PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDI 2394
P CA C ++G C + C C + G C+ C + PC G C
Sbjct: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRF 1116
Query: 2395 VCLCPYGRSGPLC 2407
C CP G GP C
Sbjct: 1117 ECRCPPGFGGPRC 1129
Score = 37.7 bits (86), Expect = 0.18
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 260 CQPHVCFHGNCSNITSNSFICECDEQFSGPFC 291
C P CF+G +T N F C C F+GP C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
Score = 37.7 bits (86), Expect = 0.18
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)
Query: 340 PCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISG 399
PC NG C+ ND C C FT C Q C P ATC++ + C +
Sbjct: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-QLWCPGQPCLPPATCEEVPDGFVCVAEAT 873
Query: 400 FTE 402
F E
Sbjct: 874 FRE 876
Score = 37.7 bits (86), Expect = 0.18
Identities = 32/146 (21%), Positives = 48/146 (32%), Gaps = 40/146 (27%)
Query: 575 CQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYC-------------------------- 608
C H+ C+D + C+C + G C +VD C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
Query: 609 --------LGNHSISVHGLCL------ALSHNCNCSGLQRYERNICEIDTEDCKSASCKN 654
+ + S++ CL S NCS L+ C++ T C++ C N
Sbjct: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLN 1184
Query: 655 GTTSTHLRGYFFRKCVPGFKGTQCEI 680
G T G C F G CE+
Sbjct: 1185 GGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 37.7 bits (86), Expect = 0.18
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 6/85 (7%)
Query: 2614 CSL-MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP 2672
CSL + C +G C + C+C G G C C+ + C G TC +
Sbjct: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA-----NPCLNGGTCRAAG 1192
Query: 2673 HGYTCFCPLGTTGIYCEQALSISDP 2697
C C +G +CE A + P
Sbjct: 1193 GVSECICNARFSGQFCEVAKGLPLP 1217
Score = 37.0 bits (84), Expect = 0.31
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 2092 SVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
+++ + +C D C NGGTC + F C CP +FTG C
Sbjct: 800 NLTAGCVSEDMCSPDPCFNGGTCLVTW-----NDFHCTCPANFTGPTC 842
Score = 35.4 bits (80), Expect = 0.90
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 2/63 (3%)
Query: 858 NPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICR 917
+PC N TCL + + HC C F G C + C C CE++ + F C+
Sbjct: 814 DPCFNGGTCLVTWN-DFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDGFVCVAE 871
Query: 918 PGF 920
F
Sbjct: 872 ATF 874
Score = 35.4 bits (80), Expect = 0.90
Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 10/93 (10%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV----SCLNN 2919
G + ++V C C C T F CRC P + G C V LN
Sbjct: 1088 GPRCEAHVDPCHSAPCARGRCH-----THPDGRFECRCPPGFGGPRCRLPVPSKECSLNV 1142
Query: 2920 LCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKT 2952
CL S C S + +C C G G+ C+ T
Sbjct: 1143 TCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPT 1174
Score = 35.0 bits (79), Expect = 1.2
Identities = 14/33 (42%), Positives = 16/33 (48%)
Query: 2613 PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC 2645
PC C NGGTC +G C C + G FC
Sbjct: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 33.9 bits (76), Expect = 2.6
Identities = 20/76 (26%), Positives = 30/76 (39%), Gaps = 15/76 (19%)
Query: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNAC 742
D C+ PC NG TC+ + F C C + G C Q + C C
Sbjct: 809 DMCSPDPCFNGGTCL--------------VTWNDFHCTCPANFTGPTCAQQL-WCPGQPC 853
Query: 743 EHNSTCKDLHLSYQCV 758
+TC+++ + CV
Sbjct: 854 LPPATCEEVPDGFVCV 869
Score = 33.5 bits (75), Expect = 3.4
Identities = 19/71 (26%), Positives = 25/71 (35%), Gaps = 1/71 (1%)
Query: 642 IDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPG 701
+ + C C NG T F C F G C + C PC ATC + P
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 702 NYFCQCVPPFK 712
+ C F+
Sbjct: 865 GFVCVAEATFR 875
Score = 33.1 bits (74), Expect = 4.4
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Query: 2375 CENNPCGNGATCVPK--SGTDIVCLCPYGRSGPLC 2407
C PC +GA CVP+ T C C G GP C
Sbjct: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRC 105
Score = 33.1 bits (74), Expect = 4.4
Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 12/79 (15%)
Query: 2573 FQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSV--GQCHASPCSLMKCGNGGTCIESGT 2630
F GC+ ++V DGH L PE + G +V G C + C +GG+C++ T
Sbjct: 576 FAGCLQDVRV----DGH---LLLPE---DLGENVLLGCERREQCRPLPCVHGGSCVDLWT 625
Query: 2631 SVYCNCTTGWKGSFCTETV 2649
C+C +G C + +
Sbjct: 626 HFRCDCARPHRGPTCADEI 644
Score = 33.1 bits (74), Expect = 4.4
Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 735 DDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYR 794
D C + C + TC + C C +++ G C Q+ C PC +TC ++ +
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 795 C 795
C
Sbjct: 868 C 868
Score = 32.7 bits (73), Expect = 5.8
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 3/80 (3%)
Query: 2060 INNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFL 2119
++ C S + T S A + + +T W SV CQ C TC IF
Sbjct: 359 VDECLSDPCLHGGTCSDTVAGYICRCPET-WGGRDCSVQLTG-CQGHTCPLAATCIPIF- 415
Query: 2120 SSGIVSFQCDCPLHFTGRFC 2139
SG+ S+ C CP G FC
Sbjct: 416 ESGVHSYVCHCPPGTHGPFC 435
Score = 32.7 bits (73), Expect = 5.8
Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Query: 374 CESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFK 433
C P ++ C+ + C+C G+ CE +D C S C + GRF+
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCH--SAPCARGRCHTHPDGRFE 1117
Query: 434 YVCIPG 439
C PG
Sbjct: 1118 CRCPPG 1123
Score = 32.3 bits (72), Expect = 7.6
Identities = 17/69 (24%), Positives = 24/69 (34%), Gaps = 13/69 (18%)
Query: 2873 DCDGTA------------CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNN 2919
DC GT C C + C +F C C P ++G C C ++
Sbjct: 209 DCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
Query: 2920 LCLHQSLCI 2928
C H C+
Sbjct: 269 PCQHGGRCL 277
Score = 32.0 bits (71), Expect = 9.9
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 4/67 (5%)
Query: 866 CLALVDANQHCICREEFEGKNCEIDVK---DCLFLSCQDYGDCEDMVNNFRCICRPGFSG 922
CL V + H + E+ G+N + + C L C G C D+ +FRC C G
Sbjct: 579 CLQDVRVDGHLLLPEDL-GENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRG 637
Query: 923 SLCEIEI 929
C EI
Sbjct: 638 PTCADEI 644
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 259 bits (663), Expect = 2e-68
Identities = 120/313 (38%), Positives = 163/313 (52%), Gaps = 16/313 (5%)
Query: 897 LSCQDYGDCEDMVNN--FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNR----- 949
L C G C + F C C + G+ CE E + C +PC+NN +C+D +
Sbjct: 317 LECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSN 375
Query: 950 FFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECL 1009
F C C P Y G C+ ++ C + PC + C+ G+ C C GY G CE +D C
Sbjct: 376 FTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCA 435
Query: 1010 SEPCLHDGVC-IDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCD 1068
S PC ++G C +DG+ H+TC+C GF G C + C +PC HG C + Y C CD
Sbjct: 436 SSPCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCD 494
Query: 1069 ADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNS 1128
C+ + N+C S PC+N C+ +G+ C+C Y G +CE D CA +
Sbjct: 495 PGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCA-----N 549
Query: 1129 VICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQ 1188
V CLNG C D G C C PGF+G+ C+I+INEC S+PC HG C D NGY C C
Sbjct: 550 VSCLNGATC-DSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCP 608
Query: 1189 PGWSGHHCENELE 1201
GW G +CE L+
Sbjct: 609 HGWVGANCEIHLQ 621
Score = 229 bits (585), Expect = 2e-59
Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 23/337 (6%)
Query: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH-- 875
C G C F C C Y G FC + Y+ C PC+NN++C +DAN+
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQ--RKPCQNNASC---IDANEKQD 372
Query: 876 -----CICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEIN 930
C+C + G+ C+ + C+ C++ C ++ F C C G+ GS CE +++
Sbjct: 373 GSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVD 432
Query: 931 ECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNC 990
C+S PC+NNGTC F CNC P + GP C ++ C +SPC C Y C
Sbjct: 433 PCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCA-HGTCRSVGTSYKC 491
Query: 991 LCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNP 1050
LC PGY G+ CE +ECLS PCL+ C D +N Y C C + + GTHCE + C +
Sbjct: 492 LCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVS 551
Query: 1051 CLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGY 1109
CL+G C C C T +C I IN+C S PC + G C +G+ C CP G+
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGW 611
Query: 1110 TGAYCEKSID----NCAEPELN----SVICLNGGICV 1138
GA CE + + AE N S+ + G +CV
Sbjct: 612 VGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCV 648
Score = 181 bits (460), Expect = 8e-45
Identities = 105/348 (30%), Positives = 160/348 (45%), Gaps = 9/348 (2%)
Query: 101 INLMNVSETSFVGCVQNTTTEDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCP 160
I L V+ T F C + + + + + G + + L++G ++FI + +
Sbjct: 237 ILLWKVTATGFQQC---SLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSI 293
Query: 161 LGLRLNVTVKQQFCQ--ESLSSEF-CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDAC 217
+ LRL + VK C ES +++ CSG GKC ++ T+SC C+ + G +C+E DAC
Sbjct: 294 VALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDAC 353
Query: 218 SFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNS 277
KPC+NN SCI+ E D + CVC P +TG+ C I C C +G + +
Sbjct: 354 QRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSG 413
Query: 278 FICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS 337
F C+C E + G CE PC S G C +T C G + + +
Sbjct: 414 FTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCA 473
Query: 338 LVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCI 397
L PC +GT C + C+C P + L C+ C S P N ATC+ Y C C+
Sbjct: 474 LSPCAHGT-CRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCL 532
Query: 398 SGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
+ + +CE D C +++CLN C + +C PG T C
Sbjct: 533 AEYKGTHCELYKDPC--ANVSCLNGATCDSDGLNGTCICAPGFTGEEC 578
Score = 176 bits (447), Expect = 2e-43
Identities = 98/317 (30%), Positives = 147/317 (46%), Gaps = 24/317 (7%)
Query: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRP-----R 589
C+ C ++ + C ++ G + E Q CQ+ A C D +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGT-FCEEYDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 590 CSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKS 649
C C Y G LC +DYC+ + + C++ C + Y + CE + C S
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRN-GATCISSLSGFTCQCPEGYFGSACEEKVDPCAS 436
Query: 650 ASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVP 709
+ C+N T +F C PGF G C ID CA PC +G TC
Sbjct: 437 SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRS----------- 484
Query: 710 PFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCE 769
V + CLC+PGY G+ CE++ ++C+ C + +TC+DL Y+CVCL++++G CE
Sbjct: 485 ---VGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCE 541
Query: 770 QESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTI 829
+ C C N +TC + C C G+TG+ C +INECDS+PC +GG C +
Sbjct: 542 LYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQ-- 599
Query: 830 PGQFVCLCPPLYTGQFC 846
P + C CP + G C
Sbjct: 600 PNGYNCHCPHGWVGANC 616
Score = 169 bits (427), Expect = 5e-41
Identities = 85/248 (34%), Positives = 123/248 (49%), Gaps = 16/248 (6%)
Query: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGI-----NHYTCDCKSGFFGTHCETN 1042
++C C Y G CE D C +PC ++ CID +++TC C G+ G C++
Sbjct: 334 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 1043 ANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGF 1101
+ C+ +PC +G C ++ + C C + C+ K++ C S PC N G C F
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHF 452
Query: 1102 TCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEIN 1161
TC C G+TG C + ID CA C + G ++ C C PG+ G +CE
Sbjct: 453 TCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGT-------SYKCLCDPGYHGLYCEEE 505
Query: 1162 INECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE-CIPNSCVH-ELCMENEPGS 1219
NEC S+PCL+ A C D +NGY C C + G HCE + C SC++ C +
Sbjct: 506 YNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNG 565
Query: 1220 TCLCTPGF 1227
TC+C PGF
Sbjct: 566 TCICAPGF 573
Score = 122 bits (305), Expect = 7e-27
Identities = 72/235 (30%), Positives = 103/235 (43%), Gaps = 18/235 (7%)
Query: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
C NG +C+S + C + G+ E + CQ+ C + C+CS
Sbjct: 401 CRNGATCISSLSG--FTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSP 458
Query: 595 SYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKN 654
+ G C +D+C S HG C ++ + C Y CE + +C SA C N
Sbjct: 459 GFTGPTCAQLIDFCA--LSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLN 516
Query: 655 GTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVV 714
T L + C+ +KGT CE+ D CA+ C NGATC D G +
Sbjct: 517 AATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATC-DSDG------------L 563
Query: 715 DGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCE 769
+G +C+C PG+ G C+ DI++C N C H +C D Y C C W G CE
Sbjct: 564 NG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 119 bits (297), Expect = 6e-26
Identities = 66/225 (29%), Positives = 95/225 (42%), Gaps = 9/225 (4%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKPCKNNGSCINKRENWDEQAYE 241
C C+S ++C C + G C+E +D C+ PC+NNG+C D +
Sbjct: 401 CRNGATCISSL--SGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYV-----DGVHFT 453
Query: 242 CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
C C P FTG C+++I C C HG C ++ S+ C CD + G +CE C+S
Sbjct: 454 CNCSPGFTGPTCAQLIDFCALSPCAHGTCRSV-GTSYKCLCDPGYHGLYCEEEYNECLSA 512
Query: 302 LFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI 361
C + + Y C + E + V C NG C + CIC+P
Sbjct: 513 PCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPG 572
Query: 362 FTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
FT C C+S P + +C Y C C G+ NCE
Sbjct: 573 FTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 114 bits (285), Expect = 2e-24
Identities = 67/211 (31%), Positives = 101/211 (47%), Gaps = 27/211 (12%)
Query: 1040 ETNANDCLSNPCLHGRCTELINE--YPCSCDADGTSTQCKIKINDCTSIPCMNEGFC--- 1094
E++AND + G+CT +E + C+C+ T C+ + + C PC N C
Sbjct: 311 ESHANDLECSG--KGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDA 367
Query: 1095 --QKSAHGFTCICPRGYTGAYCEKSIDNCA-EPELNSVICLNGGICVDGPGHTFDCRCLP 1151
++ FTC+C GYTG C+ ID C +P C NG C+ F C+C
Sbjct: 368 NEKQDGSNFTCVCLPGYTGELCQSKIDYCILDP------CRNGATCISSLSG-FTCQCPE 420
Query: 1152 GFSGQFCEININECSSSPCLHGADCEDHING--YVCKCQPGWSGHHCENELE-CIPNSCV 1208
G+ G CE ++ C+SSPC + C +++G + C C PG++G C ++ C + C
Sbjct: 421 GYFGSACEEKVDPCASSPCQNNGTC--YVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCA 478
Query: 1209 HELCMENEPGSTCLCTPGFMTCSIGLLCGDE 1239
H C CLC PG+ GL C +E
Sbjct: 479 HGTCRSVGTSYKCLCDPGYH----GLYCEEE 505
Score = 97.8 bits (242), Expect = 1e-19
Identities = 87/373 (23%), Positives = 133/373 (35%), Gaps = 61/373 (16%)
Query: 268 GNCSNITSNS-FICECDEQFSGPFCE----VSAKPCVSLLFWKRGICPNSSSAYTYECPK 322
G C+ S + F C C+EQ+ G FCE KPC + S +T C
Sbjct: 323 GKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLP 382
Query: 323 GSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNN 382
G + + ++ + L PC+NG CI + C C + C+ C S P +NN
Sbjct: 383 GYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNN 442
Query: 383 ATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTK 442
TC + C+C GFT C + ID C L C
Sbjct: 443 GTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP-----------------------CAH 479
Query: 443 NPCWFLKNVYLIHQHLCYCGVTFHGI-CQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAY- 500
C + Y C C +HG+ C++ EY L C+ +++ Y
Sbjct: 480 GTCRSVGTSYK-----CLCDPGYHGLYCEE------EYNECLSAPCLNAATCRDLVNGYE 528
Query: 501 -FFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWA 559
LA DP N S C NG +C + D +C +
Sbjct: 529 CVCLAEYKGTHCELYKDPCANVS------------CLNGATC--DSDGLNGTCICAPGFT 574
Query: 560 GNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISV--- 616
G + + N C H C D+ N C C ++G C +++ + G+ + S+
Sbjct: 575 GEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNM 634
Query: 617 --HGLCLALSHNC 627
H L + + C
Sbjct: 635 PRHSLYIIIGALC 647
Score = 90.1 bits (222), Expect = 3e-17
Identities = 49/189 (25%), Positives = 83/189 (43%), Gaps = 12/189 (6%)
Query: 174 CQESL---SSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCI 229
C+E + +S C +G C + ++C+C P F+G C +L D C+ PC + G+C
Sbjct: 427 CEEKVDPCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFCALSPCAH-GTCR 483
Query: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
+ + Y+C+C P + G C E +C C + N + C C ++ G
Sbjct: 484 SVGTS-----YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGT 538
Query: 290 FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK 349
CE+ PC ++ C + T C G + + + D++E PC +G C+
Sbjct: 539 HCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLD 598
Query: 350 ISNDVMCIC 358
N C C
Sbjct: 599 QPNGYNCHC 607
Score = 77.0 bits (188), Expect = 3e-13
Identities = 83/351 (23%), Positives = 122/351 (34%), Gaps = 78/351 (22%)
Query: 356 CICSPIFTDLLCKSIQTSCESFPLRNNATC-----KKCEKDYPCSCISGFTEKNCEKAID 410
C C + C+ +C+ P +NNA+C K+ ++ C C+ G+T + C+ ID
Sbjct: 336 CTCEEQYVGTFCEEYD-ACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Query: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPG------------CTKNPCWFLKNVYLIHQHL 458
+C L C N C + + F C G C +PC +
Sbjct: 395 YCILDP--CRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQ--------NNGT 444
Query: 459 CYC-GVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDP 517
CY GV F C G G C +ID F A +
Sbjct: 445 CYVDGVHFTCNCSP---------------GFTGPTCAQLID---FCALSP---------- 476
Query: 518 EDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQH 577
CA+G +C S S Y+ LC + G E + C +
Sbjct: 477 -----------------CAHG-TCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLN 516
Query: 578 EAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYER 637
A C+D +N C C Y G C + D C N S C + N C +
Sbjct: 517 AATCRDLVNGYECVCLAEYKGTHCELYKDPC-ANVSCLNGATCDSDGLNGTCICAPGFTG 575
Query: 638 NICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASH 688
C+ID +C S C +G + + C G+ G CEI + + H
Sbjct: 576 EECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGH 626
Score = 70.5 bits (171), Expect = 3e-11
Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
Query: 217 CSFKPCKNNGSCINKREN-------WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGN 269
C+ +PC+N G C ++ E E Y C C +G NC + C + C HGN
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 270 CSNITSNS---FICECDEQFSGPFCEVSAKPCVSLLFWKRGICP 310
CS+ +S+S ++C C+E + GP CE A P + W + P
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE-QALPSLPATGWTESMAP 150
Score = 67.4 bits (163), Expect = 2e-10
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+ + PC+ + C NG TC G + C C G+ G C ++ CD +P HH G +
Sbjct: 541 ELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECD--SNPCHH---GGS 595
Query: 2668 CISLPHGYTCFCPLGTTGIYCE 2689
C+ P+GY C CP G G CE
Sbjct: 596 CLDQPNGYNCHCPHGWVGANCE 617
Score = 63.2 bits (152), Expect = 4e-09
Identities = 46/165 (27%), Positives = 60/165 (36%), Gaps = 47/165 (28%)
Query: 181 EFCS----GHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKPCKN----------- 224
+FC+ HG C S S Y C C P + G YC+E + C PC N
Sbjct: 470 DFCALSPCAHGTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGY 527
Query: 225 ---------------------NGSCINKRE-NWDEQAYECVCHPPFTGKNCSEIIGQCQP 262
N SC+N + D C+C P FTG+ C I +C
Sbjct: 528 ECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDS 587
Query: 263 HVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRG 307
+ C HG N + C C + G CE+ L WK G
Sbjct: 588 NPCHHGGSCLDQPNGYNCHCPHGWVGANCEIH-------LQWKSG 625
Score = 60.8 bits (146), Expect = 2e-08
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 18/146 (12%)
Query: 2613 PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP 2672
PC+ C N GTC G CNC+ G+ G C + + C C+ G TC S+
Sbjct: 433 PCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFC-----ALSPCAHG-TCRSVG 486
Query: 2673 HGYTCFCPLGTTGIYCEQALS--ISDPSFRS-------NELSWMSFASFHVRKKTHIQLQ 2723
Y C C G G+YCE+ + +S P + N + A + K TH +L
Sbjct: 487 TSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEY---KGTHCELY 543
Query: 2724 FQPLAADGILFYAAQHLKAQSGDFLC 2749
P A L A +G +C
Sbjct: 544 KDPCANVSCLNGATCDSDGLNGTCIC 569
Score = 59.7 bits (143), Expect = 4e-08
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 14/88 (15%)
Query: 1131 CLNGGICVDGPGHT-----------FDCRCLPGFSGQFCEININECSSSPCLHG---ADC 1176
C NGG+C P + C C G SG C++ + C+S+PC HG +
Sbjct: 53 CRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSS 112
Query: 1177 EDHINGYVCKCQPGWSGHHCENELECIP 1204
+GY+C C G+ G +CE L +P
Sbjct: 113 SSSSDGYLCICNEGYEGPNCEQALPSLP 140
Score = 59.7 bits (143), Expect = 4e-08
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Query: 2336 VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTD 2393
+ +C CRN TCIS C+CP Y G C+ C ++PC N TC G
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCY-VDGVH 451
Query: 2394 IVCLCPYGRSGPLCTDAIN 2412
C C G +GP C I+
Sbjct: 452 FTCNCSPGFTGPTCAQLID 470
Score = 59.3 bits (142), Expect = 6e-08
Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C + C+N G C V+G F+C C P + G TC Q + C + C H + SY C
Sbjct: 434 CASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGT--CRSVGTSYKC 491
Query: 2938 LCTLGWVGRYCENK 2951
LC G+ G YCE +
Sbjct: 492 LCDPGYHGLYCEEE 505
Score = 58.5 bits (140), Expect = 1e-07
Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C +C NG C +G +C C P + G C+ ++ C +N C H C+ DQ Y+C
Sbjct: 547 CANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCL-DQPNGYNC 605
Query: 2938 LCTLGWVGRYCE 2949
C GWVG CE
Sbjct: 606 HCPHGWVGANCE 617
Score = 58.2 bits (139), Expect = 1e-07
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
Query: 685 CASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEH 744
CA+ PC+NG C +P P + G+SC C G G C+ D C N C H
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGE--PGYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 745 ---NSTCKDLHLSYQCVCLSDWEGNFCEQ 770
+S+ Y C+C +EG CEQ
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 58.2 bits (139), Expect = 1e-07
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 31/113 (27%)
Query: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCL 991
C+++PC+N G C +P++ P E GY+C
Sbjct: 48 CAAQPCRNGGVCTSRPEP-----DPQHPAPAGE---------------------PGYSCT 81
Query: 992 CAPGYTGINCEINLDECLSEPCLHDGVCIDGINH----YTCDCKSGFFGTHCE 1040
C G +G NC++ D C S PC H G C + Y C C G+ G +CE
Sbjct: 82 CPAGISGANCQLVADPCASNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 58.2 bits (139), Expect = 1e-07
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 8/81 (9%)
Query: 2339 CAHHLCRNNGTCISDNE-----NLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSG 2391
C C+NN +CI NE N C C Y+G+LCQ C +PC NGATC+ S
Sbjct: 353 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCI-SSL 411
Query: 2392 TDIVCLCPYGRSGPLCTDAIN 2412
+ C CP G G C + ++
Sbjct: 412 SGFTCQCPEGYFGSACEEKVD 432
Score = 57.8 bits (138), Expect = 2e-07
Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 46/123 (37%)
Query: 1008 CLSEPCLHDGVCID------------GINHYTCDCKSGFFGTHCETNANDCLSNPCLHGR 1055
C ++PC + GVC G Y+C C +G G +C+ A+ C SNPC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 1056 CTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCE 1115
C+ S+ G+ CIC GY G CE
Sbjct: 108 CS----------------------------------SSSSSSSDGYLCICNEGYEGPNCE 133
Query: 1116 KSI 1118
+++
Sbjct: 134 QAL 136
Score = 54.3 bits (129), Expect = 2e-06
Identities = 78/377 (20%), Positives = 137/377 (36%), Gaps = 63/377 (16%)
Query: 2613 PCSLMKCGNGGTCIE-----------SGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPH 2660
PC+ C NGG C +G Y C C G G+ C C +P H
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPC--ASNPCH 104
Query: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHV------ 2714
H + ++ S GY C C G G CEQAL + + ++
Sbjct: 105 HGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDK 164
Query: 2715 ---RKKTHIQL-QFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIIL 2770
R + + L +QP ++ ++ D C + ++S + G R +
Sbjct: 165 ILPRSQATVTLPTWQPKTGQKVVEMKWDQVEV-IPDIACGNASSNS-----SAGGRLVSF 218
Query: 2771 ETLQKVTI---NGSTWHIIKAGRVGAEGYLD---LDGINVTEKASTKMSSLDTNTDFYIG 2824
E Q ++ +T +I +V A G+ +DG +VT ++ G
Sbjct: 219 EVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQAS-------------G 265
Query: 2825 GVSSLNLVNPMAIENEPVGF--QGCIRQVIINNQELQL-TEFGAKGGSNVGDCDGTACGY 2881
G+ L + + N +GF + ++ L + G S+ D + + G
Sbjct: 266 GLVLLEEMLALG-NNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGK 324
Query: 2882 NTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCI----PDQSFSYSC 2937
T + E T + T C + G C + +C C + + CI +++C
Sbjct: 325 CTTK-PSEATFSCT-----CEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378
Query: 2938 LCTLGWVGRYCENKTSF 2954
+C G+ G C++K +
Sbjct: 379 VCLPGYTGELCQSKIDY 395
Score = 53.5 bits (127), Expect = 3e-06
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 10/103 (9%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C + CRNG C + + F+C+C + G+ C + V C ++ C + C D ++C
Sbjct: 396 CILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVD-GVHFTC 454
Query: 2938 LCTLGWVGRYCENKTSF--------STAKFMGNSYIKYIDPNY 2972
C+ G+ G C F T + +G SY DP Y
Sbjct: 455 NCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGY 497
Score = 53.1 bits (126), Expect = 4e-06
Identities = 29/79 (36%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
C L C NG TCI S + C C G+ GS C E V C C TC
Sbjct: 396 CILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPC-----ASSPCQNNGTCYVDGV 450
Query: 2674 GYTCFCPLGTTGIYCEQAL 2692
+TC C G TG C Q +
Sbjct: 451 HFTCNCSPGFTGPTCAQLI 469
Score = 52.8 bits (125), Expect = 5e-06
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 2878 ACGYNTCRNGGECT-----VNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQ 2931
AC C+N C +G+ F+C CLP + G C + C+ + C + + CI
Sbjct: 352 ACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSL 411
Query: 2932 SFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYID 2969
S ++C C G+ G CE K + N+ Y+D
Sbjct: 412 S-GFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVD 448
Score = 50.8 bits (120), Expect = 2e-05
Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
CA C+NNGTC D + C C ++G C C +PC +G TC GT C
Sbjct: 434 CASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TC-RSVGTSYKC 491
Query: 2397 LCPYGRSGPLCTDAIN 2412
LC G G C + N
Sbjct: 492 LCDPGYHGLYCEEEYN 507
Score = 50.1 bits (118), Expect = 4e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 16/89 (17%)
Query: 2339 CAHHLCRNNGTCISDNE------------NLFCECPRLYSGKLCQFAS--CENNPC--GN 2382
CA CRN G C S E C CP SG CQ + C +NPC GN
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 2383 GATCVPKSGTDIVCLCPYGRSGPLCTDAI 2411
++ S +C+C G GP C A+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 50.1 bits (118), Expect = 4e-05
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 13/87 (14%)
Query: 775 CKMNPCKNNSTCTDLYK------------SYRCECTSGWTGQNCSEEINECDSDPCMNGG 822
C PC+N CT + Y C C +G +G NC + C S+PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 823 LCHESTIPGQ-FVCLCPPLYTGQFCHQ 848
S+ ++C+C Y G C Q
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 50.1 bits (118), Expect = 4e-05
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
CA+ C N TC SD N C C ++G+ C C++NPC +G +C+ + C
Sbjct: 547 CANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQP-NGYNC 605
Query: 2397 LCPYGRSGPLC 2407
CP+G G C
Sbjct: 606 HCPHGWVGANC 616
Score = 48.1 bits (113), Expect = 1e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 11/64 (17%)
Query: 669 CVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGI 728
C G G C++ D CAS+PC +G C + DG+ C+CN GY G
Sbjct: 82 CPAGISGANCQLVADPCASNPCHHG-NCSSSSSS----------SSDGYLCICNEGYEGP 130
Query: 729 RCEQ 732
CEQ
Sbjct: 131 NCEQ 134
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
Query: 2344 CRNNGTCISD-NENLF-CECPRLYSGKLCQ-FASCENNPCGNGATCV----PKSGTDIVC 2396
C G C + +E F C C Y G C+ + +C+ PC N A+C+ + G++ C
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378
Query: 2397 LCPYGRSGPLCTDAIN 2412
+C G +G LC I+
Sbjct: 379 VCLPGYTGELCQSKID 394
Score = 45.8 bits (107), Expect = 7e-04
Identities = 28/88 (31%), Positives = 36/88 (40%), Gaps = 14/88 (15%)
Query: 813 CDSDPCMNGGLCHESTIPGQ----------FVCLCPPLYTGQFCHQRYNLCDLLHNPCR- 861
C + PC NGG+C P + C CP +G C + C NPC
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPC--ASNPCHH 105
Query: 862 -NNSTCLALVDANQHCICREEFEGKNCE 888
N S+ + CIC E +EG NCE
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 44.3 bits (103), Expect = 0.002
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 5/57 (8%)
Query: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNR----FFCNCEPEYHGPFCE 964
+ C C G SG+ C++ + C+S PC ++G C ++ + C C Y GP CE
Sbjct: 78 YSCTCPAGISGANCQLVADPCASNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 43.1 bits (100), Expect = 0.004
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 198 YSCHCQPPFSGKYCQEL-DACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
YSC C SG CQ + D C+ PC ++G+C + + Y C+C+ + G NC +
Sbjct: 78 YSCTCPAGISGANCQLVADPCASNPC-HHGNCSSSSSS-SSDGYLCICNEGYEGPNCEQA 135
Query: 257 I 257
+
Sbjct: 136 L 136
Score = 41.6 bits (96), Expect = 0.013
Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 9/73 (12%)
Query: 2331 IENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVP 2388
I+ C + CAH CR+ GT C C Y G C ++ C + PC N ATC
Sbjct: 469 IDFCALSPCAHGTCRSVGTSYK------CLCDPGYHGLYCEEEYNECLSAPCLNAATCRD 522
Query: 2389 -KSGTDIVCLCPY 2400
+G + VCL Y
Sbjct: 523 LVNGYECVCLAEY 535
Score = 41.6 bits (96), Expect = 0.013
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 3/76 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
C C N TC C C Y G C+ C N C NGATC G + C
Sbjct: 509 CLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATC-DSDGLNGTC 567
Query: 2397 LCPYGRSGPLCTDAIN 2412
+C G +G C IN
Sbjct: 568 ICAPGFTGEECDIDIN 583
Score = 40.4 bits (93), Expect = 0.028
Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 16/83 (19%)
Query: 859 PCRNNSTCLALVDAN-QH----------CICREEFEGKNCEIDVKDCLFLSCQDYGDCED 907
PCRN C + + + QH C C G NC++ C C +G+C
Sbjct: 52 PCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCH-HGNCSS 110
Query: 908 MVNN----FRCICRPGFSGSLCE 926
++ + CIC G+ G CE
Sbjct: 111 SSSSSSDGYLCICNEGYEGPNCE 133
Score = 36.6 bits (83), Expect = 0.40
Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 18/100 (18%)
Query: 2607 GQCHASPCSLMKCGNGGTCIE--SGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
G+ HA+ ++C G C S + C C + G+FC E C + C
Sbjct: 310 GESHAND---LECSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRKP-----CQN 360
Query: 2665 GATCISLPH-----GYTCFCPLGTTGIYCEQALS--ISDP 2697
A+CI +TC C G TG C+ + I DP
Sbjct: 361 NASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDP 400
Score = 35.4 bits (80), Expect = 0.90
Identities = 13/38 (34%), Positives = 16/38 (42%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC 2910
D D C N C +GG C ++C C W G C
Sbjct: 579 DIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 33.1 bits (74), Expect = 4.4
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 14/75 (18%)
Query: 2074 ASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQ-------DVCHNGGTCHAIFLSSGIVSF 2126
AS +DA++ G + +T V +CQ D C NG TC S + F
Sbjct: 362 ASCIDANEKQDGSN--FTCVCLPGYTGELCQSKIDYCILDPCRNGATC-----ISSLSGF 414
Query: 2127 QCDCPLHFTGRFCEK 2141
C CP + G CE+
Sbjct: 415 TCQCPEGYFGSACEE 429
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 250 bits (639), Expect = 1e-65
Identities = 315/1272 (24%), Positives = 482/1272 (37%), Gaps = 292/1272 (22%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGK--YCQELDACS--FKPCKNNGSCINKRENWDEQ 238
CS + +C++ S Y C C F+G C ++D C+ C+N G C+N
Sbjct: 1419 CSINAQCVNTPGS--YRCACSEGFTGDGFTCSDVDECAENINLCEN-GQCLNV-----PG 1470
Query: 239 AYECVCHPPFT----GKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQF----SGPF 290
AY C C FT ++C +I ++C G C+N+ F C CD+ + +G
Sbjct: 1471 AYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPG-MFHCICDDGYELDRTGGN 1529
Query: 291 CEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQ-----NGT 345
C C + G+C N+ Y CP + + C G
Sbjct: 1530 C-TDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGD 1588
Query: 346 DCIKISNDV-------MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCIS 398
+ + ++ C CS L K+ CE+ P N+ E C
Sbjct: 1589 GSLSCNTEIGVGVSRSSCCCS------LGKAWGNPCETCPPVNST-----EYYTLCPGGE 1637
Query: 399 GFTEKNCE---KAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNP----CWFLKNV 451
GF + ID C+ L C C N G F+ C G + C +
Sbjct: 1638 GFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQCECPQGYYLSEDTRICEDIDEC 1696
Query: 452 YLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDA 511
+ H +C G ++ + EY+ G G C + ++ + + N T
Sbjct: 1697 FA-HPGVCGPGTCYNTLGNYTCICPPEYMQVNG-----GHNCMDMRKSFCYRSYNGT--- 1747
Query: 512 TYVNDPEDNNSSCWFPHEGTKEICA----------NGCSCLSEEDSQEYRYLCFLRWAGN 561
T N+ P TK +C C + +++ +C
Sbjct: 1748 TCENE---------LPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFT 1798
Query: 562 MYLENTTDDQENECQH------EAVCKDEINRPRCSC--SLSYIGRLCVV-NVDYCL-GN 611
+ +EC+ VC ++I RC C SY L V ++D C G+
Sbjct: 1799 FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGD 1858
Query: 612 HSISVHGLCLAL--SHNCNCSGLQRYERNICEIDTEDCKSAS--CKNGTTSTHLRGYFFR 667
+ + C+ S+ C C+ + N +D +C C +G L+G +
Sbjct: 1859 NLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLC-VDLQGSYQC 1917
Query: 668 KCVPGFKGTQCE---IDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPG 724
C GFK +Q + +D+DEC HPC NG TC + G+Y C C P F++ CL
Sbjct: 1918 ICHNGFKASQDQTMCMDVDECERHPCGNG-TCKNTVGSYNCLCYPGFELTHNNDCL---- 1972
Query: 725 YVGIRCEQDIDDC--ILNACEHNSTCKDLHLSYQCVCLSDWE----GNFCEQESNECKMN 778
DID+C N C + S++C+C +E G C ++NEC
Sbjct: 1973 --------DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI-DTNECVAL 2023
Query: 779 PCK-NNSTCTDLYKSYRCECTSGWT--GQNCSEEINECDSDP--CMNGGLCHESTIPGQF 833
P + TC +L S+RC C G+ +NC + INECD DP C+ G + PG F
Sbjct: 2024 PGSCSPGTCQNLEGSFRCICPPGYEVKSENCID-INECDEDPNICLFGSC---TNTPGGF 2079
Query: 834 VCLCPPLYT----GQFC---HQRYNLCDLLHNPCRNNSTCLALVDANQHCICRE---EFE 883
CLCPP + G+ C Q + + + C S A C C + E
Sbjct: 2080 QCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKC---SVPKAFNTTKAKCCCSKMPGEGW 2136
Query: 884 GKNCEI----------------------------DVKDCLFLS--CQDYGDCEDMVNNFR 913
G CE+ DV +CL C + G C + +FR
Sbjct: 2137 GDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN-GQCINTDGSFR 2195
Query: 914 CICRPGFS----GSLCEIEINECS-SEPCKNNGTCVDLTNRFFCNCEPEYH-GPF--CEL 965
C C G++ G C ++ +ECS PC NGTC ++ F CNC + GP CE
Sbjct: 2196 CECPMGYNLDYTGVRC-VDTDECSIGNPC-GNGTCTNVIGSFECNCNEGFEPGPMMNCE- 2252
Query: 966 DVNKCKISPCLDEENCVYRTDGYNCLCAPGYT------------------------GINC 1001
D+N+C +P L C+ Y C C GY G+ C
Sbjct: 2253 DINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMC 2312
Query: 1002 E-----------------------INLDECLSEPCL-HDGVCIDGINHYTCDCKSGF--- 1034
+ ++ +EC ++P + +G C++ I Y C+C GF
Sbjct: 2313 KNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSS 2372
Query: 1035 -FGTHCETNANDCLSNPCLHGRCT------ELINEYPCSCDAD-GTSTQCKI-------- 1078
GT C N L C L+ + C CD G QC++
Sbjct: 2373 SSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQ 2432
Query: 1079 ----------------KINDCTSIP--CMNEGFCQKSAHGFTCICPRGYT----GAYCEK 1116
I++C +P C N G C + F C C GYT G C
Sbjct: 2433 YKKICPHGPGYTTDGRDIDECKVMPNLCTN-GQCINTMGSFRCFCKVGYTTDISGTSCI- 2490
Query: 1117 SIDNCAE-PELNSVICLNGGICVDGPGHTFDCRCLPGF----SGQFCEININECSSSPCL 1171
+D C++ P+ + IC N +G ++ C C G+ G+ C+ +++EC +
Sbjct: 2491 DLDECSQSPKPCNYICKN----TEG---SYQCSCPRGYVLQEDGKTCK-DLDECQTKQHN 2542
Query: 1172 HGADCEDHINGYVCKCQPGWSGHH--CENELEC--IPNSCVHELCMENEPGS-TCLCTPG 1226
C + + G+ CKC PG++ HH C + EC P+ C + +N PGS +C C G
Sbjct: 2543 CQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRG 2602
Query: 1227 FMTCSIGLLCGD 1238
F + GL C D
Sbjct: 2603 FSLDATGLNCED 2614
Score = 221 bits (564), Expect = 7e-57
Identities = 273/1105 (24%), Positives = 422/1105 (38%), Gaps = 228/1105 (20%)
Query: 168 TVKQQFC---QESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFS----GKYCQELDACSFK 220
T +Q C E + + +G+C++ S + C C F GK C + D C+
Sbjct: 567 TPTKQACIDIDECIQNGVLCKNGRCVNTDGS--FQCICNAGFELTTDGKNCVDHDECTTT 624
Query: 221 PCKNNGSCINKRENWDEQAYECVCHPPFT----GKNCSEIIGQCQ-PHVCFHGNCSNITS 275
NG CIN ++ +++C+C P F G+ C+++ +CQ P +C +G+C N +
Sbjct: 625 NMCLNGMCIN-----EDGSFKCICKPGFVLAPNGRYCTDV-DECQTPGICMNGHCIN-SE 677
Query: 276 NSFICECDEQFS----GPFCEVSAKPCVSLLFWKRGIC---------------------- 309
SF C+C + G C + K+G+C
Sbjct: 678 GSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGF 737
Query: 310 --------PNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICS 359
+S+ + C G D++E +L P C NG C + C C+
Sbjct: 738 GEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGI-CENLRGSYRCNCN 796
Query: 360 ----PIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF---TEKNCEKAIDHC 412
P + C I + L +N C+ Y C+C G+ TE + I+ C
Sbjct: 797 SGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC 856
Query: 413 KLLSINCLNEEWCFNIIGRFKYVCIPGCT------------KNPCWFLKNVYLIHQHLCY 460
+ S C+N C N +G F C PG K CW N+ +
Sbjct: 857 E--SNPCVNGA-CRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWL--NIQDSRCEVNI 911
Query: 461 CGVTFHG-ICQDKGPA--------QFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDA 511
G T C G A + + G A +G C+ V + F +
Sbjct: 912 NGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVF--PGVCPNG 969
Query: 512 TYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQ 571
VN + C EG + G CL Q C+L+W
Sbjct: 970 RCVNSKGSFHCEC---PEGLT-LDGTGRVCLDIRMEQ-----CYLKW------------D 1008
Query: 572 ENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCN--- 628
E+EC H K ++ C C+ +G + C + LC + N
Sbjct: 1009 EDECIHPVPGKFRMDA--CCCA---VGAAWGTECEECPKPGTKEYETLCPRGAGFANRGD 1063
Query: 629 -CSGLQRYER-NICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE---IDID 683
+G Y+ N C+ C C+N G F +C GF E DID
Sbjct: 1064 VLTGRPFYKDINECKAFPGMCTYGKCRNTI------GSFKCRCNSGFALDMEERNCTDID 1117
Query: 684 ECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNA 741
EC P C +G C++ PG++ C+C ++ G++ ++ DID+C N
Sbjct: 1118 ECRISPDLCGSGI-CVNTPGSFECECFEGYE----------SGFMMMKNCMDIDECERNP 1166
Query: 742 CE-HNSTCKDLHLSYQCVCLSDWEGNFCEQES---NECKM--NPCKNNSTCTDLYKSYRC 795
TC + S+QC C E + ++ NEC + N C+N C ++ +Y+C
Sbjct: 1167 LLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK-CVNMIGTYQC 1225
Query: 796 ECTSGWTGQNCSEEINECDSDPCMNGGLCHEST-IPGQFVCLCPPLYTGQFCHQRYNLCD 854
C G+ + + D MNGG + T G + C C Y
Sbjct: 1226 SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGY------------- 1272
Query: 855 LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRC 914
AL+ + C +E CE + C D G C ++ +RC
Sbjct: 1273 -------------ALMPDGRSCADIDE-----CENNPDIC------DGGQCTNIPGEYRC 1308
Query: 915 ICRPGFSGSL----CEIEINEC--SSEPCKNNGTCVDLTNRFFCNCEPEY---HGPFCEL 965
+C GF S+ C I++NEC +S C G C + F C+C+ Y G
Sbjct: 1309 LCYDGFMASMDMKTC-IDVNECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCT 1366
Query: 966 DVNKCKISP--CLDEENCVYRTDGYNCLCAPGY--TGINCEINLDECL--SEPCLHDGVC 1019
DV++C+I C +C+ + C C G+ GI C I+LDEC + C + C
Sbjct: 1367 DVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQC 1425
Query: 1020 IDGINHYTCDCKSGFFGTHCE-TNANDCLS--NPCLHGRCTELINEYPCSCDADGT---- 1072
++ Y C C GF G ++ ++C N C +G+C + Y C C+ T
Sbjct: 1426 VNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASD 1485
Query: 1073 STQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGY----TGAYCEKSIDNCAEPELNS 1128
S C+ I++C+ G C F CIC GY TG C ID CA+P
Sbjct: 1486 SRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADP---- 1539
Query: 1129 VICLNGGICVDGPGHTFDCRCLPGF 1153
+ C+N G+CV+ PG ++C C P F
Sbjct: 1540 INCVN-GLCVNTPGR-YECNCPPDF 1562
Score = 221 bits (562), Expect = 1e-56
Identities = 311/1248 (24%), Positives = 465/1248 (37%), Gaps = 259/1248 (20%)
Query: 112 VGCVQNTTTEDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPS---PCPLGLRLNVT 168
VGCV N L FG R G + N++ + VG + G + PC +N T
Sbjct: 1569 VGCVDNRVGNCYLKFGPRGDGSLSCNTE-IGVGVSRSSCCCSLGKAWGNPCETCPPVNST 1627
Query: 169 VKQQFCQ--------------ESLSS-----EFCSGHGKCLSEAWSKTYSCHCQPPF--- 206
C E + C G G C++ S + C C +
Sbjct: 1628 EYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQG-GNCINTFGS--FQCECPQGYYLS 1684
Query: 207 -SGKYCQELDACSFKP--CKNNGSCINKRENWDEQAYECVCHPPFT----GKNCSEIIGQ 259
+ C+++D C P C G+C N N Y C+C P + G NC ++
Sbjct: 1685 EDTRICEDIDECFAHPGVC-GPGTCYNTLGN-----YTCICPPEYMQVNGGHNCMDM--- 1735
Query: 260 CQPHVCFHG----NCSN-----ITSNSFICECD--EQFSGPFCEVSAKPCVSLLFWKRGI 308
+ C+ C N +T C + + ++ P CE P + + I
Sbjct: 1736 -RKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKP-CEPCPTPGTADF---KTI 1790
Query: 309 CPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIFT--D 364
C N +T++ G + D+ E +P C NG CI C C F+ D
Sbjct: 1791 CGNIPG-FTFDIHTGKA-----VDIDECKEIPGICANGV-CINQIGSFRCECPTGFSYND 1843
Query: 365 LL--CKSIQTSCESFPL-RNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSI-NCL 420
LL C+ I L + NA C Y C C +GF +D + L I N
Sbjct: 1844 LLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC 1903
Query: 421 NEEWCFNIIGRFKYVCIPG---------------CTKNPCW--FLKNVYLIHQHLCYCG- 462
+ C ++ G ++ +C G C ++PC KN + LCY G
Sbjct: 1904 SHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGF 1963
Query: 463 -VTFHGICQDKGPAQ--FEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPE- 518
+T + C D F V + G +C I ++ L C E D +
Sbjct: 1964 ELTHNNDCLDIDECSSFFGQVCRNG-------RCFNEIGSFKCL---CNEGYELTPDGKN 2013
Query: 519 --DNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLC---FLRWAGNMYLENTTDDQEN 573
D N P C+ G +C + E S +R +C + + N N D+ N
Sbjct: 2014 CIDTNECVALPGS-----CSPG-TCQNLEGS--FRCICPPGYEVKSENCIDINECDEDPN 2065
Query: 574 ECQHEAVCKDEINRPRCSCSLSYI----GRLCV-VNVDYCLGNHS---ISVHGLCLALSH 625
C + C + +C C ++ GR C +C N SV
Sbjct: 2066 ICLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA 2124
Query: 626 NCNCSGLQRY----ERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEID 681
C CS + +C D E C G + VP T+ D
Sbjct: 2125 KCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGT-----------VPSLHDTR--ED 2171
Query: 682 IDECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
++EC P C NG CI+ G++ C+C + N Y G+RC D D+C +
Sbjct: 2172 VNECLESPGICSNGQ-CINTDGSFRCECPMGY----------NLDYTGVRCV-DTDECSI 2219
Query: 740 NACEHNSTCKDLHLSYQCVCLSDWEGN---FCEQESNECKMNPCKNNSTCTDLYKSYRCE 796
N TC ++ S++C C +E CE + NEC NP C + + SY C
Sbjct: 2220 GNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECT 2278
Query: 797 CTSGWTGQN----------CSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYT---- 842
C G+ + C+E +++C+S G +C + G F+C+CPP
Sbjct: 2279 CPIGYALREDQKMCKDLDECAEGLHDCES----RGMMC--KNLIGTFMCICPPGMARRPD 2332
Query: 843 GQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKD--------- 893
G+ C N C C N C+ ++ + C C E F+ + + D
Sbjct: 2333 GEGCVDE-NECRTKPGICENGR-CVNII-GSYRCECNEGFQSSSSGTECLDNRQGLCFAE 2389
Query: 894 CLFLSCQDYGDCEDMVNNFRCICRPGFS-GSLCEI------------------------E 928
L CQ ++V C C G G CE+ +
Sbjct: 2390 VLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRD 2449
Query: 929 INECSSEP--CKNNGTCVDLTNRFFCNCEPEY----HGPFCELDVNKCKISPCLDEENCV 982
I+EC P C NG C++ F C C+ Y G C +D+++C SP C
Sbjct: 2450 IDECKVMPNLC-TNGQCINTMGSFRCFCKVGYTTDISGTSC-IDLDECSQSPKPCNYICK 2507
Query: 983 YRTDGYNCLCAPGYT----GINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTH 1038
Y C C GY G C+ +LDEC ++ +C++ + +TC C GF H
Sbjct: 2508 NTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHH 2566
Query: 1039 --CETNANDCLSNPCLHGR---CTELINEYPCSCDA----DGTSTQCKIKINDCTSIPCM 1089
C N N+C S P L G C + C C D T C+ +++C
Sbjct: 2567 TACIDN-NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DVDECDGNHRC 2624
Query: 1090 NEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCA-EPELNSVICLNGGICVDGPGHTFDCR 1148
G CQ G+ C CP+GY Y + C E E ++ C + G ++ C
Sbjct: 2625 QHG-CQNILGGYRCGCPQGYIQHY---QWNQCVDENECSNPNACGSASCYNTLG-SYKCA 2679
Query: 1149 CLPGFS-GQFCEI--NINECSSS--PCLHGADCEDHINGYVCKCQPGW 1191
C GFS QF ++NECSSS PC +G C + GY+C C PG+
Sbjct: 2680 CPSGFSFDQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCGCPPGY 2725
Score = 220 bits (560), Expect = 2e-56
Identities = 335/1400 (23%), Positives = 501/1400 (35%), Gaps = 395/1400 (28%)
Query: 177 SLSSEFCSGHGKCLSEAWSKTYSCHC----QPPFSGKYCQELDACSFKPCK-NNGSCINK 231
+L + C+ +G C E +Y C+C +P SG+ C ++D C +NG C N
Sbjct: 773 ALDPDICA-NGIC--ENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNT 829
Query: 232 RENWDEQAYECVCHPPF---TGKNCSEIIGQCQPHVCFHGNC--------------SNIT 274
+Y C C P + T E I +C+ + C +G C S ++
Sbjct: 830 -----PGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLS 884
Query: 275 SNSFIC------ECDEQFSGPFCEVS-------AKPCVSL-LFWKR-------------- 306
S IC C CEV+ ++ C +L W
Sbjct: 885 STGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRG 944
Query: 307 -------------------GICPN-----SSSAYTYECPKGSSSQNGETDVSEFSLVPCQ 342
G+CPN S ++ ECP+G + + + C
Sbjct: 945 LARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCY 1004
Query: 343 ---NGTDCI-----KISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPC 394
+ +CI K D C + + T CE P K K+Y
Sbjct: 1005 LKWDEDECIHPVPGKFRMDACCCA-------VGAAWGTECEECP-------KPGTKEYET 1050
Query: 395 SCISG---------FTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
C G T + K I+ CK C + C N IG FK C G +
Sbjct: 1051 LCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK-CRNTIGSFKCRCNSGFALD-- 1107
Query: 446 WFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAA 505
+N I + + GIC + P FE +C ++ F +
Sbjct: 1108 MEERNCTDIDECRISPDLCGSGICVNT-PGSFEC------------ECFEGYESGFMMMK 1154
Query: 506 NCTE------------DATYVNDPEDNNSSCWFPHE--GTKEICA--NGCSCLSEEDSQE 549
NC + T VN C HE ++E C N CS LS+ +
Sbjct: 1155 NCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECS-LSDNLCRN 1213
Query: 550 ---------YRYLCFLRWAGNMYLENTTDDQENECQH---EAVCKDEINRPRCSCSLSYI 597
Y+ C + + TD E + + C + CSCS Y
Sbjct: 1214 GKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYA 1273
Query: 598 ----GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRY----------ERNICEID 643
GR C ++D C N I G C + C + + N C+++
Sbjct: 1274 LMPDGRSCA-DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLN 1332
Query: 644 TEDCKSASCKNGTTSTHLRGYFFRKCVPGF---KGTQCEIDIDEC--ASHPCKNGATCID 698
+ C C+N +G F C G+ KGT D+DEC +H C A+C++
Sbjct: 1333 SNICMFGECEN------TKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN 1386
Query: 699 QPGNYFCQCVPPF-----KVVD----------------------GFSCLCNPGYV--GIR 729
PG++ C C + K +D + C C+ G+ G
Sbjct: 1387 IPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFT 1446
Query: 730 CEQDIDDCI--LNACEHNSTCKDLHLSYQCVCLSDW----EGNFCEQESNECKMNPCKNN 783
C D+D+C +N CE N C ++ +Y+C C + + C Q+ +EC
Sbjct: 1447 C-SDVDECAENINLCE-NGQCLNVPGAYRCECEMGFTPASDSRSC-QDIDECSFQNICVF 1503
Query: 784 STCTDLYKSYRCECTSGW----TGQNCSEEINECDSDP--CMNGGLCHESTIPGQFVCLC 837
TC +L + C C G+ TG NC+ +I+EC +DP C+N GLC + PG++ C C
Sbjct: 1504 GTCNNLPGMFHCICDDGYELDRTGGNCT-DIDEC-ADPINCVN-GLCVNT--PGRYECNC 1558
Query: 838 PPLY----TGQFC-HQRYNLCDLLHNPCRNNS----TCLALVDANQHCICR-EEFEGKNC 887
PP + TG C R C L P + S T + + + C C + G C
Sbjct: 1559 PPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPC 1618
Query: 888 EI-----------------------------DVKDCLFLS--CQDYGDCEDMVNNFRCIC 916
E D+ +C L CQ G+C + +F+C C
Sbjct: 1619 ETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQG-GNCINTFGSFQCEC 1677
Query: 917 RPGFSGS----LCEIEINECSSEP-CKNNGTCVDLTNRFFCNCEPEY------HG----- 960
G+ S +CE +I+EC + P GTC + + C C PEY H
Sbjct: 1678 PQGYYLSEDTRICE-DIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
Query: 961 -----------------PF--------CELDVNKCKISPCLDEENC-VYRTDGYNCLCA- 993
PF C +V K PC E C T + +C
Sbjct: 1737 KSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPC---EPCPTPGTADFKTICGN 1793
Query: 994 -PGYT---GINCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSGFF------------- 1035
PG+T +++DEC P + +GVCI+ I + C+C +GF
Sbjct: 1794 IPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDE 1853
Query: 1036 ----GTHCETNA----------------------------NDCLS--NPCLHGRCTELIN 1061
C+ NA N+CL N C HG C +L
Sbjct: 1854 CSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQG 1913
Query: 1062 EYPCSC----DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKS 1117
Y C C A T C + +++C PC N G C+ + + C+C G+ +
Sbjct: 1914 SYQCICHNGFKASQDQTMC-MDVDECERHPCGN-GTCKNTVGSYNCLCYPGFELTHNNDC 1971
Query: 1118 IDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF----SGQFCEININECSSSP--CL 1171
+D +C NG C + G +F C C G+ G+ C I+ NEC + P C
Sbjct: 1972 LDIDECSSFFGQVCRNGR-CFNEIG-SFKCLCNEGYELTPDGKNC-IDTNECVALPGSCS 2028
Query: 1172 HGADCEDHINGYVCKCQPGW--SGHHCENELEC--IPNSCVHELCMENEPGSTCLCTPGF 1227
G C++ + C C PG+ +C + EC PN C+ C G CLC PGF
Sbjct: 2029 PGT-CQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGF 2087
Query: 1228 MTCSIGLLCGDEIRRITCLT 1247
+ G C D R+ C T
Sbjct: 2088 VLSDNGRRCFD-TRQSFCFT 2106
Score = 209 bits (533), Expect = 3e-53
Identities = 298/1200 (24%), Positives = 459/1200 (38%), Gaps = 214/1200 (17%)
Query: 151 VMASGPSPCPLGLR-LNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF--- 206
V A G P GL LN T+ C+ + C +G+C+ S Y C C +
Sbjct: 476 VGAGGQGPIITGLTILNQTI--DICKHH--ANLCL-NGRCIPTVSS--YRCECNMGYKQD 528
Query: 207 SGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPF----TGKNCSEIIGQCQP 262
+ C ++D C+ PC NG C+N +Y C CH F T + C +I Q
Sbjct: 529 ANGDCIDVDECTSNPC-TNGDCVN-----TPGSYYCKCHAGFQRTPTKQACIDIDECIQN 582
Query: 263 HV-CFHGNCSNITSNSFICECDEQF----SGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317
V C +G C N T SF C C+ F G C V C + G+C N ++
Sbjct: 583 GVLCKNGRCVN-TDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDGSFK 640
Query: 318 YECPKG-SSSQNGE--TDVSEFSLVP-CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTS 373
C G + NG TDV E C NG CI C C P L
Sbjct: 641 CICKPGFVLAPNGRYCTDVDECQTPGICMNG-HCINSEGSFRCDCPP---GLAVGMDGRV 696
Query: 374 CESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFK 433
C +R+ +C G + C + S C C N F
Sbjct: 697 CVDTHMRS-------------TCYGGIKKGVCVRPFPGAVTKSECC-----CANPDYGFG 738
Query: 434 YVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKC 493
C P KN FHG+C G + + + C
Sbjct: 739 EPCQPCPAKN------------------SAEFHGLC-SSGVGITVDGRDINECALDPDIC 779
Query: 494 QGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHE--GTKEICANGCSCLSEEDSQEYR 551
I + C ++ Y +P+ + +C E + +C NG C + S
Sbjct: 780 ANGICENLRGSYRCNCNSGY--EPDASGRNCIDIDECLVNRLLCDNGL-CRNTPGS---- 832
Query: 552 YLCFLRWAGNMYLENTTDDQENECQH----EAVCKDEINRPRCSCS----LSYIGRLCVV 603
Y C E T + NEC+ C++ + C CS LS G +C+
Sbjct: 833 YSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICI- 891
Query: 604 NVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRG 663
S+ G C + C N + +E C + G+ R
Sbjct: 892 ----------DSLKGTCWLNIQDSRC----EVNINGATLKSECCATLGAAWGSPCE--RC 935
Query: 664 YFFRKCVPG---FKGTQCEIDIDECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFS 718
C G KG CE D++EC P C NG C++ G++ C+C P +DG
Sbjct: 936 ELDTACPRGLARIKGVTCE-DVNECEVFPGVCPNG-RCVNSKGSFHCEC-PEGLTLDGTG 992
Query: 719 CLCNPGYVGIRCEQ-----DIDDCI--------LNAC----------EHNSTCKDLHLSY 755
+C + IR EQ D D+CI ++AC E K Y
Sbjct: 993 RVC----LDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEY 1048
Query: 756 QCVCLSD---------WEGNFCEQESNECKMNP-CKNNSTCTDLYKSYRCECTSGWT--- 802
+ +C G ++ NECK P C + S++C C SG+
Sbjct: 1049 ETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDM 1108
Query: 803 -GQNCSEEINECDSDPCMNG-GLCHESTIPGQFVCLCPPLYTGQFCHQR--YNLCDLLHN 858
+NC+ +I+EC P + G G+C + PG F C C Y F + ++ + N
Sbjct: 1109 EERNCT-DIDECRISPDLCGSGICVNT--PGSFECECFEGYESGFMMMKNCMDIDECERN 1165
Query: 859 P--CRNNSTCLALVDANQHCIC---REEFEGKNCEIDVKDCLFLS--CQDYGDCEDMVNN 911
P CR TC+ + + C C E + +D+ +C C++ G C +M+
Sbjct: 1166 PLLCR-GGTCVN-TEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN-GKCVNMIGT 1222
Query: 912 FRCICRPGFSGSLCE---IEINECSSEPCKNNGTCVDLTNRFFCNCEPEY----HGPFCE 964
++C C PG+ + +I+EC + C + + C+C Y G C
Sbjct: 1223 YQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC- 1281
Query: 965 LDVNKCKISPCL-DEENCVYRTDGYNCLCAPGYTG---INCEINLDEC-LSEPCLHDGVC 1019
D+++C+ +P + D C Y CLC G+ + I+++EC L+ G C
Sbjct: 1282 ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGEC 1341
Query: 1020 IDGINHYTCDCKSGFF---GTHCETNANDC---LSNPCLHGRCTELINEYPCSCDAD--G 1071
+ + C C+ G+ GT T+ ++C N +H C + + CSC G
Sbjct: 1342 ENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIG 1401
Query: 1072 TSTQCKIKINDCT--SIPCMNEGFCQKSAHGFTCICPRGYTG-AYCEKSIDNCAEPELNS 1128
+C I +++C+ + C C + + C C G+TG + +D CAE N
Sbjct: 1402 NGIKC-IDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAE---NI 1457
Query: 1129 VICLNGGICVDGPGHTFDCRCLPGFS----GQFCEININECS-SSPCLHGADCEDHINGY 1183
+C NG C++ PG + C C GF+ + C+ +I+ECS + C+ G C + +
Sbjct: 1458 NLCENGQ-CLNVPG-AYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGT-CNNLPGMF 1513
Query: 1184 VCKCQPGW----SGHHCENELECI-PNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
C C G+ +G +C + EC P +CV+ LC+ C C P F G+ C D
Sbjct: 1514 HCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD 1573
Score = 206 bits (525), Expect = 2e-52
Identities = 295/1133 (26%), Positives = 437/1133 (38%), Gaps = 235/1133 (20%)
Query: 255 EIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL--LFWKRGICP 310
E I +CQ P +C GNC N T SF CEC + G + + C + F G+C
Sbjct: 1649 EDIDECQELPGLCQGGNCIN-TFGSFQCECPQ---GYYLSEDTRICEDIDECFAHPGVCG 1704
Query: 311 -----NSSSAYTYECPKGSSSQNGETDVSEFSLVPCQ---NGTDCIKISNDV-------M 355
N+ YT CP NG + + C NGT C N++ M
Sbjct: 1705 PGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC---ENELPFNVTKRM 1761
Query: 356 CICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFT-EKNCEKA--IDHC 412
C C T + K+ CE P A K C I GFT + + KA ID C
Sbjct: 1762 CCC----TYNVGKAWNKPCEPCPTPGTADFKTI-----CGNIPGFTFDIHTGKAVDIDEC 1812
Query: 413 KLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFL---------------KNVYLIHQ- 456
K + C N C N IG F+ C G + N + +N I+
Sbjct: 1813 KEIPGICANGV-CINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSP 1871
Query: 457 --HLCYCGVTF----HGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTED 510
+ C C F +G C D+ ++ S G C + +Y + N +
Sbjct: 1872 GSYRCECAAGFKLSPNGACVDRNECL-----EIPNVCSHG-LCVDLQGSYQCICHNGFKA 1925
Query: 511 ATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDD 570
+ + + C E + C NG +C + S Y LC+ G N
Sbjct: 1926 S-------QDQTMCMDVDECERHPCGNG-TCKNTVGS--YNCLCY---PGFELTHNNDCL 1972
Query: 571 QENECQ-------HEAVCKDEINRPRCSCSLSYI----GRLCVVNVDYCLGNHSISVHGL 619
+EC C +EI +C C+ Y G+ C+ + + C+ G
Sbjct: 1973 DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI-DTNECVALPGSCSPGT 2031
Query: 620 CLALSHNCNCSGLQRYER--------NICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVP 671
C L + C YE N C+ D C SC T+ G F C P
Sbjct: 2032 CQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSC------TNTPGGFQCLCPP 2085
Query: 672 GF----KGTQC----------EIDIDEC----ASHPCKNGATCIDQPGNYF---CQCVPP 710
GF G +C + +C A + K C PG + C+ P
Sbjct: 2086 GFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPK 2145
Query: 711 FKVVDGFSCLCNPGYVGIRC----EQDIDDCILNA--CEHNSTCKDLHLSYQCVCLS--- 761
V F LC G+ + +D+++C+ + C N C + S++C C
Sbjct: 2146 DDEV-AFQDLCPYGHGTVPSLHDTREDVNECLESPGICS-NGQCINTDGSFRCECPMGYN 2203
Query: 762 -DWEGNFCEQESNECKM-NPCKNNSTCTDLYKSYRCECTSGWTG---QNCSEEINECDSD 816
D+ G C +++EC + NPC N TCT++ S+ C C G+ NC E+INEC +
Sbjct: 2204 LDYTGVRCV-DTDECSIGNPC-GNGTCTNVIGSFECNCNEGFEPGPMMNC-EDINECAQN 2260
Query: 817 PCMNGGLCHESTIPGQFVCLCPPLYT----GQFCHQRYNLCDLLHNPCRNNSTCLALVDA 872
P + C + G + C CP Y + C + LH+ C L+
Sbjct: 2261 PLLCAFRCMNTF--GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGT 2318
Query: 873 NQHCICREEF----EGKNCEIDVKDCLFLS--CQDYGDCEDMVNNFRCICRPGFSGSLCE 926
CIC +G+ C +D +C C++ G C +++ ++RC C GF S
Sbjct: 2319 FM-CICPPGMARRPDGEGC-VDENECRTKPGICEN-GRCVNIIGSYRCECNEGFQSSSSG 2375
Query: 927 IEINE-----CSSEP----CKNNGTCVDLTNRFFCNCEP-EYHGPFCELDVNKCKISPCL 976
E + C +E C+ + +L + C C+ G CEL C +
Sbjct: 2376 TECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCEL----CPLPG-- 2429
Query: 977 DEENCVYRTDGYNCLC--APGYTGINCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSG 1033
T Y +C PGYT +I DEC P L +G CI+ + + C CK G
Sbjct: 2430 --------TAQYKKICPHGPGYTTDGRDI--DECKVMPNLCTNGQCINTMGSFRCFCKVG 2479
Query: 1034 FF----GTHCETNANDCLSNP--CLHGRCTELINEYPCSC------DADGTST----QCK 1077
+ GT C + ++C +P C + C Y CSC DG + +C+
Sbjct: 2480 YTTDISGTSC-IDLDECSQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQ 2537
Query: 1078 IKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAY--CEKSIDNCAEPELNSVICLNGG 1135
K ++C + C + GFTC CP G+T + C + + ++P L C G
Sbjct: 2538 TKQHNCQFL-------CVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSL----CGAKG 2586
Query: 1136 ICVDGPGHTFDCRCLPGFS----GQFCEININECSSSP-CLHGADCEDHINGYVCKCQPG 1190
IC + PG +F C C GFS G CE +++EC + C HG C++ + GY C C G
Sbjct: 2587 ICQNTPG-SFSCECQRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGCPQG 2642
Query: 1191 WSGHH----CENELECI-PNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
+ H+ C +E EC PN+C C C C GF C D
Sbjct: 2643 YIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHD 2695
Score = 182 bits (461), Expect = 6e-45
Identities = 304/1236 (24%), Positives = 426/1236 (34%), Gaps = 289/1236 (23%)
Query: 188 KCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPP 247
+C++ C CQ + G YC + C C+N G CI C C
Sbjct: 152 RCMNGGTCADDHCQCQKGYIGTYCGQ-PVCE-NGCQNGGRCIGPN--------RCACVYG 201
Query: 248 FTGKNCSE--IIGQCQPHV---CFHGNCSNITSNSFIC--ECDEQFSGP--FCEVSAKPC 298
FTG C G C V G + I +C + P C +PC
Sbjct: 202 FTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPC 261
Query: 299 VSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMC 356
+RG PN T C DV E +P CQ G +CI C
Sbjct: 262 ------RRGFIPN---IRTGAC----------QDVDECQAIPGICQGG-NCINTVGSFEC 301
Query: 357 IC----SPIFTDLLCKSIQTSCESFP-LRNNATCKKCEKDYPCSCISGF-TEKNCEKAID 410
C T C+ I C P + C Y C C G+ T + + ID
Sbjct: 302 RCPAGHKQSETTQKCEDID-ECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
Query: 411 HCKLLSINCL-NEEWCFNIIGRF-KYVCIPGCTKNPCWFLKNVYLI--------HQHLCY 460
+ + L N + GR K C C CW + + ++ LC
Sbjct: 361 QRTGMCFSGLVNGRCAQELPGRMTKMQCC--CEPGRCWGIGTIPEACPVRGSEEYRRLCM 418
Query: 461 CGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDN 520
G+ GI G + G G G G + Y ++ P N
Sbjct: 419 DGLPMGGIPGSAGS-------RPGGTGGNGFAPSGNGNGY------GPGGTGFIPIPGGN 465
Query: 521 NSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEA- 579
S P G + A G + G L T D C+H A
Sbjct: 466 GFS---PGVGGAGVGAGGQGPII---------------TGLTILNQTID----ICKHHAN 503
Query: 580 -----VCKDEINRPRCSCSLSY--IGRLCVVNVDYCLGNHSISVHGLCLALSHNCNC-SG 631
C ++ RC C++ Y ++VD C N + + S+ C C +G
Sbjct: 504 LCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAG 563
Query: 632 LQRYERNICEIDTEDC--KSASCKNGTTSTHLRGYFFRKCVPGFK----GTQCEIDIDEC 685
QR ID ++C CKNG + G F C GF+ G C +D DEC
Sbjct: 564 FQRTPTKQACIDIDECIQNGVLCKNG-RCVNTDGSFQCICNAGFELTTDGKNC-VDHDEC 621
Query: 686 -ASHPCKNGATCIDQPGNYFCQCVPPFKVV-DGFSC----------LCNPGYV-----GI 728
++ C NG CI++ G++ C C P F + +G C +C G+
Sbjct: 622 TTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSF 680
Query: 729 RCEQDIDDCI--LNACEHNSTCKDLHLSYQC-------VCLSDWEGNFCEQE-------- 771
RC DC L C D H+ C VC+ + G + E
Sbjct: 681 RC-----DCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDY 735
Query: 772 --SNECKMNPCKNNSTCTDLYKS--------------------------------YRCEC 797
C+ P KN++ L S YRC C
Sbjct: 736 GFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNC 795
Query: 798 TSGW----TGQNCSEEINECDSDPCM-NGGLCHESTIPGQFVCLCPPLY---TGQFCHQR 849
SG+ +G+NC +I+EC + + + GLC + PG + C CPP Y T +
Sbjct: 796 NSGYEPDASGRNCI-DIDECLVNRLLCDNGLCRNT--PGSYSCTCPPGYVFRTETETCED 852
Query: 850 YNLCDLLHNPCRNNSTCLALVDANQHC-----------ICREEFEG--------KNCEID 890
N C+ NPC N + L N C IC + +G CE++
Sbjct: 853 INECE--SNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVN 910
Query: 891 VKD-------CLFLSCQDYGDCEDMVNNFRC---ICRPGFSGSLCEIEINECSSEP--CK 938
+ C L CE + C + R G CE ++NEC P C
Sbjct: 911 INGATLKSECCATLGAAWGSPCERCELDTACPRGLAR--IKGVTCE-DVNECEVFPGVCP 967
Query: 939 NNGTCVDLTNRFFCNCEP----EYHGPFCELDVNKCKISPCLDEENCVYRTDGY----NC 990
NG CV+ F C C + G C LD+ + DE+ C++ G C
Sbjct: 968 -NGRCVNSKGSFHCECPEGLTLDGTGRVC-LDIRMEQCYLKWDEDECIHPVPGKFRMDAC 1025
Query: 991 LCAPGYT-GINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSG---------FFGTHCE 1040
CA G G CE EC G Y C G G
Sbjct: 1026 CCAVGAAWGTECE----ECPK----------PGTKEYETLCPRGAGFANRGDVLTGRPFY 1071
Query: 1041 TNANDCLSNP--CLHGRCTELINEYPCSCDA----DGTSTQCKIKINDCTSIPCM-NEGF 1093
+ N+C + P C +G+C I + C C++ D C I++C P + G
Sbjct: 1072 KDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC-TDIDECRISPDLCGSGI 1130
Query: 1094 CQKSAHGFTCICPRGY-TGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPG 1152
C + F C C GY +G K+ + E E N ++C GG CV+ G +F C C G
Sbjct: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLC-RGGTCVNTEG-SFQCDCPLG 1188
Query: 1153 F----SGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGWSG----HHCENELEC- 1202
S + C ++INECS S L C + I Y C C PG+ C + EC
Sbjct: 1189 HELSPSREDC-VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECM 1247
Query: 1203 IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
I N C +E C C+ G+ G C D
Sbjct: 1248 IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCAD 1283
Score = 137 bits (344), Expect = 2e-31
Identities = 210/918 (22%), Positives = 326/918 (35%), Gaps = 208/918 (22%)
Query: 185 GHGKCLSEAWSKTYSCHCQPPFSGKY---CQELDACS--FKPCKNNGSCINKRENWDEQA 239
G+G C + S Y+C C P F + C ++D CS F NG C N + +
Sbjct: 1944 GNGTCKNTVGS--YNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFN-----EIGS 1996
Query: 240 YECVCHPPFT----GKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEV 293
++C+C+ + GKNC + +C P C G C N+ SF C C P EV
Sbjct: 1997 FKCLCNEGYELTPDGKNCIDT-NECVALPGSCSPGTCQNL-EGSFRCICP-----PGYEV 2049
Query: 294 SAKPCVSL----------LFWKRGICPNSSSAYTYECPKGSS-SQNGETDVS---EFSLV 339
++ C+ + LF G C N+ + CP G S NG F
Sbjct: 2050 KSENCIDINECDEDPNICLF---GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFT 2106
Query: 340 PCQNGTDCIKIS---NDVMCICSPI-------------------FTDLLC---------- 367
+NG + + C CS + F DL
Sbjct: 2107 NFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH 2166
Query: 368 ---KSIQTSCESFPLRNNATCKKCEKDYPCSCISGFT-EKNCEKAIDHCKLLSINCLNEE 423
+ + ES + +N C + + C C G+ + + +D + N
Sbjct: 2167 DTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG 2226
Query: 424 WCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQL 483
C N+IG F+ C G P +++ Q+ C C + +E +
Sbjct: 2227 TCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR----CMNTF-GSYECTCPI 2281
Query: 484 GFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLS 543
G+A E +K + + E A ++D E C K +
Sbjct: 2282 GYALREDQK----------MCKDLDECAEGLHDCESRGMMC-------KNLIGT------ 2318
Query: 544 EEDSQEYRYLCFLRWAGNMYLENTTDDQENECQ------HEAVCKDEINRPRCSCSLSYI 597
+ +C A E D ENEC+ C + I RC C+ +
Sbjct: 2319 ------FMCICPPGMARRPDGEGCVD--ENECRTKPGICENGRCVNIIGSYRCECNEGFQ 2370
Query: 598 GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTT 657
CL N GLC A C + RN+ + +C C G
Sbjct: 2371 SSSSGTE---CLDNRQ----GLCFAEVLQTICQ-MASSSRNL--VTKSEC---CCDGGRG 2417
Query: 658 STHL--------RGYFFRKCVPGFKGTQCEIDIDECASHP--CKNGATCIDQPGNYFCQC 707
H + + C G T DIDEC P C NG CI+ G++ C C
Sbjct: 2418 WGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQ-CINTMGSFRCFC 2476
Query: 708 VPPFKV-VDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDW--- 763
+ + G SC+ D+D+C + N CK+ SYQC C +
Sbjct: 2477 KVGYTTDISGTSCI------------DLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQ 2524
Query: 764 -EGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCS-EEINECDSDPCMNG 821
+G C+ + +EC+ C + + C+C G+T + + + NEC S P + G
Sbjct: 2525 EDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCG 2583
Query: 822 --GLCHESTIPGQFVCLCPPLY----TGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH 875
G+C + PG F C C + TG C + CD H C++ C ++
Sbjct: 2584 AKGICQNT--PGSFSCECQRGFSLDATGLNCED-VDECDGNHR-CQHG--CQNIL-GGYR 2636
Query: 876 CICRE----EFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFS----GSLCEI 927
C C + ++ C +D +C + C + + +++C C GFS S C
Sbjct: 2637 CGCPQGYIQHYQWNQC-VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACH- 2694
Query: 928 EINECSSEPCKNNGTCVDLTNRFFCNCEPEYH---------------GPFCELDVNKCKI 972
++NECSS N C + + C C P Y+ G + LD
Sbjct: 2695 DVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTE---- 2750
Query: 973 SPCLDEENCVYRTDGYNC 990
+DEEN + Y C
Sbjct: 2751 ---VDEENALSPEACYEC 2765
Score = 130 bits (326), Expect = 3e-29
Identities = 111/398 (27%), Positives = 174/398 (43%), Gaps = 69/398 (17%)
Query: 903 GDCEDMVNNFRCICRPGFSGSL---CEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYH 959
G C V+++RC C G+ C I+++EC+S PC NG CV+ ++C C +
Sbjct: 508 GRCIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPC-TNGDCVNTPGSYYCKCHAGFQ 565
Query: 960 GPFCE---LDVNKCKISPCLDEENCVYRTDG-YNCLCAPGYT----GINCEINLDECLSE 1011
+ +D+++C + L + TDG + C+C G+ G NC ++ DEC +
Sbjct: 566 RTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTT 624
Query: 1012 PCLHDGVCIDGINHYTCDCKSGFF----GTHCETNANDCLS-NPCLHGRCTELINEYPCS 1066
+G+CI+ + C CK GF G +C T+ ++C + C++G C + C
Sbjct: 625 NMCLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEGSFRCD 683
Query: 1067 CDA------DG---------TSTQCKIKINDC----------TSIPCMNEGF-----CQ- 1095
C DG ++ IK C + C N + CQ
Sbjct: 684 CPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQP 743
Query: 1096 ---KSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPG 1152
K++ F +C G + I+ CA L+ IC NG IC + G ++ C C G
Sbjct: 744 CPAKNSAEFHGLCSSGVGITVDGRDINECA---LDPDICANG-ICENLRG-SYRCNCNSG 798
Query: 1153 F----SGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGW----SGHHCENELECI 1203
+ SG+ C I+I+EC + L C + Y C C PG+ CE+ EC
Sbjct: 799 YEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE 857
Query: 1204 PNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIR 1241
N CV+ C N C C+PG S GL+C D ++
Sbjct: 858 SNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLK 895
Score = 120 bits (300), Expect = 3e-26
Identities = 132/546 (24%), Positives = 198/546 (36%), Gaps = 116/546 (21%)
Query: 773 NECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC-SEEINECDSDPCMNGGLCHESTIPG 831
N+C + C+N+ + C C+SG C S+ I +C S CMNGG C +
Sbjct: 108 NQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQC-SVRCMNGGTCADDH--- 163
Query: 832 QFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDV 891
C C Y G +C Q + N C+N C+ C C F G CE D
Sbjct: 164 ---CQCQKGYIGTYCGQ-----PVCENGCQNGGRCI----GPNRCACVYGFTGPQCERDY 211
Query: 892 KDCLFLSCQDYGDCEDMVNNFRC-------ICRPGFSGSLCEIEINECSSEPCKNNGTCV 944
+ G C VNN C +C + +LC I PC+
Sbjct: 212 RT---------GPCFTQVNNQMCQGQLTGIVC----TKTLCCATIGRAWGHPCEMCPAQP 258
Query: 945 DLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE-ENCVYRTDGYNCLCAPGY----TGI 999
R F P C+ DV++C+ P + + NC+ + C C G+ T
Sbjct: 259 QPCRRGFI---PNIRTGACQ-DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQ 314
Query: 1000 NCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSGFF----GTHCETNANDCLSNPCLHG 1054
CE ++DEC P + G C + + Y C C G+ G+ C + ++G
Sbjct: 315 KCE-DIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNG 373
Query: 1055 RCTE----LINEYPCSCDAD-----GTSTQ-CKIKINDCTSIPCMNEGFCQKSAHGFTCI 1104
RC + + + C C+ GT + C ++ ++ CM +G G
Sbjct: 374 RCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCM-DGLPMGGIPGSAGS 432
Query: 1105 CPRGYTG-AYCEKSIDNCAEPELNSVICLNGG---------------------------- 1135
P G G + N P I + GG
Sbjct: 433 RPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILN 492
Query: 1136 ----ICVDGPGHTFDCRCLPGFSGQFCE-------------ININECSSSPCLHGADCED 1178
IC + RC+P S CE I+++EC+S+PC +G DC +
Sbjct: 493 QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNG-DCVN 551
Query: 1179 HINGYVCKCQPGW----SGHHCENELECIPNS--CVHELCMENEPGSTCLCTPGFMTCSI 1232
Y CKC G+ + C + ECI N C + C+ + C+C GF +
Sbjct: 552 TPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTD 611
Query: 1233 GLLCGD 1238
G C D
Sbjct: 612 GKNCVD 617
Score = 100 bits (248), Expect = 3e-20
Identities = 70/217 (32%), Positives = 108/217 (49%), Gaps = 31/217 (14%)
Query: 1048 SNPCLHGRCTELINEYPCSC------DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGF 1101
+N CL+GRC ++ Y C C DA+G I +++CTS PC N G C + +
Sbjct: 502 ANLCLNGRCIPTVSSYRCECNMGYKQDANGDC----IDVDECTSNPCTN-GDCVNTPGSY 556
Query: 1102 TCICPRGYTGAYCEKS---IDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFS---- 1154
C C G+ +++ ID C + N V+C NG CV+ G +F C C GF
Sbjct: 557 YCKCHAGFQRTPTKQACIDIDECIQ---NGVLCKNGR-CVNTDG-SFQCICNAGFELTTD 611
Query: 1155 GQFCEININECSSSP-CLHGADCEDHINGYVCKCQPGW----SGHHCENELEC-IPNSCV 1208
G+ C ++ +EC+++ CL+G C + + C C+PG+ +G +C + EC P C+
Sbjct: 612 GKNC-VDHDECTTTNMCLNGM-CINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICM 669
Query: 1209 HELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
+ C+ +E C C PG G +C D R TC
Sbjct: 670 NGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTC 706
Score = 92.4 bits (228), Expect = 6e-18
Identities = 150/653 (22%), Positives = 218/653 (33%), Gaps = 166/653 (25%)
Query: 665 FFRKCVPGFK----GTQCEIDI--DECASHPCKNGATCIDQPGNYFCQCVPP------FK 712
F C PG+K G QC + I + C C C G C +
Sbjct: 93 FHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVR 152
Query: 713 VVDGFSCL-----CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF 767
++G +C C GY+G C Q + + N C++ C + +C C+ + G
Sbjct: 153 CMNGGTCADDHCQCQKGYIGTYCGQPVCE---NGCQNGGRCIGPN---RCACVYGFTGPQ 206
Query: 768 CEQESNECKMNPC---KNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLC 824
CE+ + + PC NN C C T C I PC
Sbjct: 207 CER---DYRTGPCFTQVNNQMCQGQLTGIVC------TKTLCCATIGRAWGHPC------ 251
Query: 825 HESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEG 884
+C PCR A Q
Sbjct: 252 --------------------------EMCPAQPQPCRRGFIPNIRTGACQ---------- 275
Query: 885 KNCEIDVKDCLFLS--CQDYGDCEDMVNNFRCICRPGFSGS----LCEIEINECSSEP-- 936
DV +C + CQ G+C + V +F C C G S CE +I+ECS P
Sbjct: 276 -----DVDECQAIPGICQG-GNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGI 328
Query: 937 CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEE-----------NCVYRT 985
C+ G C + +FC C Y V S C+D+ C
Sbjct: 329 CE-TGECSNTVGSYFCVCPRGY--------VTSTDGSRCIDQRTGMCFSGLVNGRCAQEL 379
Query: 986 DG----YNCLCAPGYT-GIN-----CEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFF 1035
G C C PG GI C + E C+ DG+ + GI G
Sbjct: 380 PGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCM-DGLPMGGIPGSAGSRPGGTG 438
Query: 1036 GTHCETNAN----------------DCLSNPCLHGRCTELINEYPCSCD---ADGTSTQC 1076
G + N +P + G + P + T C
Sbjct: 439 GNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDIC 498
Query: 1077 KIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAE-PELNSVICLNGG 1135
K N C + G C + + C C GY + + +C + E S C NG
Sbjct: 499 KHHANLCLN------GRCIPTVSSYRCECNMGYK----QDANGDCIDVDECTSNPCTNGD 548
Query: 1136 ICVDGPGHTFDCRCLPGF----SGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPG 1190
CV+ PG ++ C+C GF + Q C I+I+EC + L C + + C C G
Sbjct: 549 -CVNTPG-SYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNGRCVNTDGSFQCICNAG 605
Query: 1191 W----SGHHCENELEC-IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
+ G +C + EC N C++ +C+ + C+C PGF+ G C D
Sbjct: 606 FELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTD 658
Score = 75.5 bits (184), Expect = 8e-13
Identities = 71/285 (24%), Positives = 109/285 (38%), Gaps = 44/285 (15%)
Query: 968 NKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYT 1027
N+C + C + + + C C+ G C + S C++ G C D +H
Sbjct: 108 NQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCAD--DH-- 163
Query: 1028 CDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSI 1086
C C+ G+ GT+C N C +G RC I C+C T QC+ D +
Sbjct: 164 CQCQKGYIGTYC---GQPVCENGCQNGGRC---IGPNRCACVYGFTGPQCE---RDYRTG 214
Query: 1087 PC---MNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH 1143
PC +N CQ G C T C +I G C P
Sbjct: 215 PCFTQVNNQMCQGQLTGIVC------TKTLCCATIGRAW-----------GHPCEMCPAQ 257
Query: 1144 TFDCR--CLPGFSGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGW----SGHHC 1196
CR +P C+ +++EC + P + G +C + + + C+C G + C
Sbjct: 258 PQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKC 316
Query: 1197 ENELEC--IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDE 1239
E+ EC IP C C C+C G++T + G C D+
Sbjct: 317 EDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQ 361
Score = 51.6 bits (122), Expect = 1e-05
Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 15/79 (18%)
Query: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVP 2388
K+I+ C V C N GTC D+ C+C + Y G C CEN C NG C+
Sbjct: 144 KSIQQCSVR------CMNGGTCADDH----CQCQKGYIGTYCGQPVCENG-CQNGGRCIG 192
Query: 2389 KSGTDIVCLCPYGRSGPLC 2407
+ C C YG +GP C
Sbjct: 193 PNR----CACVYGFTGPQC 207
Score = 44.3 bits (103), Expect = 0.002
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 21/87 (24%)
Query: 2604 RSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
+S+ QC ++C NGGTC + +C C G+ G++C + V C+ + C
Sbjct: 144 KSIQQCS------VRCMNGGTCADD----HCQCQKGYIGTYCGQPV--CE------NGCQ 185
Query: 2664 RGATCISLPHGYTCFCPLGTTGIYCEQ 2690
G CI P+ C C G TG CE+
Sbjct: 186 NGGRCIG-PN--RCACVYGFTGPQCER 209
Score = 41.6 bits (96), Expect = 0.013
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSF--CTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
C +C+ S C+C GW G+ C + D + H CS A C++ P Y
Sbjct: 1378 CDMHASCLNIPGSFKCSCREGWIGNGIKCIDL----DECSNGTHQCSINAQCVNTPGSYR 1433
Query: 2677 CFCPLGTTG 2685
C C G TG
Sbjct: 1434 CACSEGFTG 1442
Score = 39.3 bits (90), Expect = 0.062
Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-ETVSTCDPEHDPPHHCSR 2664
+ +C SP CG+G C+ + S C C G++ F + D P C R
Sbjct: 1116 IDECRISPDL---CGSG-ICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLC-R 1170
Query: 2665 GATCISLPHGYTCFCPLG 2682
G TC++ + C CPLG
Sbjct: 1171 GGTCVNTEGSFQCDCPLG 1188
Score = 38.5 bits (88), Expect = 0.11
Identities = 27/87 (31%), Positives = 32/87 (36%), Gaps = 5/87 (5%)
Query: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
P A + V +C A P GG CI + S C C G K S T+ D
Sbjct: 267 PNIRTGACQDVDECQAIPGICQ----GGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC 322
Query: 2656 HDPPHHCSRGATCISLPHGYTCFCPLG 2682
P C G C + Y C CP G
Sbjct: 323 SIIPGICETG-ECSNTVGSYFCVCPRG 348
Score = 38.5 bits (88), Expect = 0.11
Identities = 29/80 (36%), Positives = 34/80 (42%), Gaps = 9/80 (11%)
Query: 2328 GKNIENCHVPWCAHH--LCRNNGTCISDNENLFCECPRLY----SGKLCQFASCENNPCG 2381
G I N + C HH LC N G CI + CEC Y +G C +NPC
Sbjct: 487 GLTILNQTIDICKHHANLCLN-GRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCT 545
Query: 2382 NGATCVPKSGTDIVCLCPYG 2401
NG CV G+ C C G
Sbjct: 546 NG-DCVNTPGS-YYCKCHAG 563
Score = 38.5 bits (88), Expect = 0.11
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 1/64 (1%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
C NG CI S C C TG+ + D + + C R A CI+ P Y C
Sbjct: 1819 CANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE 1877
Query: 2679 CPLG 2682
C G
Sbjct: 1878 CAAG 1881
Score = 37.0 bits (84), Expect = 0.31
Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
Query: 2866 KGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLN--NLC 2921
KG + D D G + C C +F C C W GN C C N + C
Sbjct: 1360 KGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQC 1419
Query: 2922 LHQSLCIPDQSFSYSCLCTLGWVG 2945
+ C+ + SY C C+ G+ G
Sbjct: 1420 SINAQCV-NTPGSYRCACSEGFTG 1442
Score = 37.0 bits (84), Expect = 0.31
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 1/59 (1%)
Query: 2622 GGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCP 2680
GG CI + S C C G+ S T D P C G TC + YTC CP
Sbjct: 1663 GGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTLGNYTCICP 1720
Score = 37.0 bits (84), Expect = 0.31
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 14/88 (15%)
Query: 2599 HPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDP 2654
H A +C + P CG G C + S C C G+ G C E V CD
Sbjct: 2565 HHTACIDNNECGSQPSL---CGAKGICQNTPGSFSCECQRGFSLDATGLNC-EDVDECDG 2620
Query: 2655 EHDPPHHCSRGATCISLPHGYTCFCPLG 2682
H C G C ++ GY C CP G
Sbjct: 2621 N----HRCQHG--CQNILGGYRCGCPQG 2642
Score = 36.2 bits (82), Expect = 0.53
Identities = 17/63 (26%), Positives = 27/63 (42%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
G C + S C+C G+ T + D H+C A+C+++P + C C G
Sbjct: 1339 GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREG 1398
Query: 2683 TTG 2685
G
Sbjct: 1399 WIG 1401
Score = 36.2 bits (82), Expect = 0.53
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDW---AGNTCNQSVSCLN--NLCLHQSLC 2927
D D + G N C+ +C + ++ C C + C CL N+C H LC
Sbjct: 1850 DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSH-GLC 1908
Query: 2928 IPDQSFSYSCLCTLGW 2943
+ D SY C+C G+
Sbjct: 1909 V-DLQGSYQCICHNGF 1923
Score = 35.8 bits (81), Expect = 0.69
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 14/83 (16%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCI 2669
CS GTC +C C G++ G CT+ DP + C G C+
Sbjct: 1495 CSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN-----CVNGL-CV 1548
Query: 2670 SLPHGYTCFCP----LGTTGIYC 2688
+ P Y C CP L TG+ C
Sbjct: 1549 NTPGRYECNCPPDFQLNPTGVGC 1571
Score = 35.8 bits (81), Expect = 0.69
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 11/73 (15%)
Query: 2346 NNGTCISDNENLFCECPR----LYSGKLC-QFASCE-NNPCGNGATCVPKSGTDIVCLCP 2399
+NG CI+ + + CECP Y+G C C NPCGNG TC G+ C C
Sbjct: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNG-TCTNVIGS-FECNCN 2240
Query: 2400 YG-RSGPL--CTD 2409
G GP+ C D
Sbjct: 2241 EGFEPGPMMNCED 2253
Score = 35.0 bits (79), Expect = 1.2
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGW--KGSFCTETVSTCDPEHDPPHHCSRG 2665
+C A P S + GTC S C C G+ K C + ++ CD + P+ C G
Sbjct: 2019 ECVALPGSC----SPGTCQNLEGSFRCICPPGYEVKSENCID-INECDED---PNICLFG 2070
Query: 2666 ATCISLPHGYTCFCPLG 2682
+ C + P G+ C CP G
Sbjct: 2071 S-CTNTPGGFQCLCPPG 2086
Score = 34.3 bits (77), Expect = 2.0
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 15/94 (15%)
Query: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLY----SGKLCQ-FASCENNPCGNGA 2384
+I+ C V + L +NG C + + C CP Y + C+ CE+NPC NGA
Sbjct: 810 DIDECLV----NRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA 865
Query: 2385 TCVPKSGTDIVCLCPYG----RSGPLCTDAINIT 2414
C G+ C C G +G +C D++ T
Sbjct: 866 -CRNNLGS-FNCECSPGSKLSSTGLICIDSLKGT 897
Score = 34.3 bits (77), Expect = 2.0
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
+C C+ + S C C+ G+ G T S D + + C G C+++P Y C
Sbjct: 1418 QCSINAQCVNTPGSYRCACSEGFTGDGFT--CSDVDECAENINLCENGQ-CLNVPGAYRC 1474
Query: 2678 FCPLGTT 2684
C +G T
Sbjct: 1475 ECEMGFT 1481
Score = 33.5 bits (75), Expect = 3.4
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 12/85 (14%)
Query: 2868 GSNVGDC--DGTACGYNTCRNGGECTVNGTTFSCRCL----PDWAGNTCNQSVSCLNNLC 2921
G ++ +C D C C N + G+ + C C PD +G C CL N
Sbjct: 766 GRDINECALDPDICANGICEN-----LRGS-YRCNCNSGYEPDASGRNCIDIDECLVNRL 819
Query: 2922 LHQSLCIPDQSFSYSCLCTLGWVGR 2946
L + + SYSC C G+V R
Sbjct: 820 LCDNGLCRNTPGSYSCTCPPGYVFR 844
Score = 33.1 bits (74), Expect = 4.4
Identities = 18/77 (23%), Positives = 31/77 (40%), Gaps = 7/77 (9%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C ++PC+ G C+ + S YC C G++ + + D C G
Sbjct: 536 VDECTSNPCT------NGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNG 589
Query: 2666 ATCISLPHGYTCFCPLG 2682
C++ + C C G
Sbjct: 590 -RCVNTDGSFQCICNAG 605
Score = 32.7 bits (73), Expect = 5.8
Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
G CI + +S C C G+K + + + +P C+ G C++ P Y C C G
Sbjct: 508 GRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNP---CTNG-DCVNTPGSYYCKCHAG 563
Score = 32.7 bits (73), Expect = 5.8
Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 5/80 (6%)
Query: 2603 GRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHC 2662
GR + +C P C NG C S CNC +G++ D C
Sbjct: 766 GRDINECALDPDI---CANG-ICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLC 821
Query: 2663 SRGATCISLPHGYTCFCPLG 2682
G C + P Y+C CP G
Sbjct: 822 DNGL-CRNTPGSYSCTCPPG 840
Score = 32.3 bits (72), Expect = 7.6
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 8/67 (11%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWK---GSFCTETVSTCDPEHDPPHHCSRGATCISLPHGY 2675
C CI S S C C G+K C + + C + P+ CS G C+ L Y
Sbjct: 1861 CQRNADCINSPGSYRCECAAGFKLSPNGACVDR-NEC---LEIPNVCSHG-LCVDLQGSY 1915
Query: 2676 TCFCPLG 2682
C C G
Sbjct: 1916 QCICHNG 1922
Score = 32.0 bits (71), Expect = 9.9
Identities = 19/74 (25%), Positives = 28/74 (37%), Gaps = 6/74 (8%)
Query: 2876 GTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFS 2934
G C CRN C C +TC ++S+ + C++ C D
Sbjct: 107 GNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH--- 163
Query: 2935 YSCLCTLGWVGRYC 2948
C C G++G YC
Sbjct: 164 --CQCQKGYIGTYC 175
Score = 32.0 bits (71), Expect = 9.9
Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLNNLCLHQSLCIPD 2930
D D + G + C +C ++ C C + G+ TC+ C N+ L ++ +
Sbjct: 1408 DLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLN 1467
Query: 2931 QSFSYSCLCTLGW 2943
+Y C C +G+
Sbjct: 1468 VPGAYRCECEMGF 1480
Score = 32.0 bits (71), Expect = 9.9
Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 3/76 (3%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
G C++ S C C G+K S + D + H C G TC + Y C C G
Sbjct: 1906 GLCVDLQGSYQCICHNGFKAS--QDQTMCMDVDECERHPCGNG-TCKNTVGSYNCLCYPG 1962
Query: 2683 TTGIYCEQALSISDPS 2698
+ L I + S
Sbjct: 1963 FELTHNNDCLDIDECS 1978
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 249 bits (636), Expect = 3e-65
Identities = 305/1253 (24%), Positives = 461/1253 (36%), Gaps = 273/1253 (21%)
Query: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF----SGKYCQELDACSFKPCKNNGSCINK 231
E L + +G+C++ S + C C F GK C+++D CS + NG CIN
Sbjct: 533 ECLQNGRICNNGRCINTDGS--FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCIN- 589
Query: 232 RENWDEQAYECVCHPPF----TGKNCSEIIGQCQ-PHVCFHGNCSNITSNSFICECDEQF 286
++ +++C+C P F G+ C + I +C+ P +C +G C N T S+ CEC F
Sbjct: 590 ----EDGSFKCICKPGFQLASDGRYCKD-INECETPGICMNGRCVN-TDGSYRCEC---F 640
Query: 287 SGPFCEVSAKPCVSLLF-------WKRGIC------------------------------ 309
G + + CV +KRG C
Sbjct: 641 PGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP 700
Query: 310 PNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIF----T 363
+S+ Y C G + +D++E +L P C NG C + CIC+ + T
Sbjct: 701 AQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI-CENLRGTYKCICNSGYEVDST 759
Query: 364 DLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTE----KNCEKAIDHCKLLSINC 419
C I + L +N C+ + C+C GF K CE ID C+ S C
Sbjct: 760 GKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCED-IDECE--SSPC 816
Query: 420 LNEEWCFNIIGRF-------------KYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFH 466
+N C N G F K +CI K CW + V + G T
Sbjct: 817 INGV-CKNSPGSFICECSSESTLDPTKTICIE-TIKGTCW--QTVIDGRCEININGATLK 872
Query: 467 G-ICQDKGPA--------QFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDP 517
C G A Q + + G++ +G +C+ + + F ++ VN
Sbjct: 873 SQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVF--PGVCKNGLCVN-- 928
Query: 518 EDNNSSCWFPHEGTKEICANGC------SCLSEEDSQEYRYLCFLRWAGNMYLE------ 565
+ C P T + C +C + +E C L AG ++
Sbjct: 929 TRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEE----CTLPIAGRHRMDACCCSV 984
Query: 566 ----NTTDDQE----NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVH 617
T + +E N ++E +C P + G+ +++ C S+ H
Sbjct: 985 GAAWGTEECEECPMRNTPEYEELCP---RGPGFATKEITNGKPFFKDINECKMIPSLCTH 1041
Query: 618 GLCLAL--SHNCNCS---GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPG 672
G C S C C L ERN +ID C G + G F KC G
Sbjct: 1042 GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTPGDFECKCDEG 1100
Query: 673 FKG-----TQCEIDIDECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFS-CLCNPG 724
++ C +DIDEC P C+ G C + G+Y C+C P ++ S C+
Sbjct: 1101 YESGFMMMKNC-MDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQLSPNISACI---- 1154
Query: 725 YVGIRCEQDIDDCILNA--CEHNSTCKDLHLSYQCVCLSDWEGN----FCEQESNECKMN 778
DI++C L+A C N C +L YQC C + FC + +EC +
Sbjct: 1155 --------DINECELSAHLCP-NGRCVNLIGKYQCACNPGYHSTPDRLFC-VDIDECSIM 1204
Query: 779 PCKNNSTCTDLYKSYRCECTSGWT---GQNCSEEINECDSDP-CMNGGLCHESTIPGQFV 834
+ CT+ SY C C G+ Q +I+EC+ +P +GG C + IPG++
Sbjct: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--TNIPGEYR 1262
Query: 835 CLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC 894
CLC Y G + C VD N+ C+++ C
Sbjct: 1263 CLC---YDGFMASEDMKTC----------------VDVNE------------CDLNPNIC 1291
Query: 895 LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCE---IEINEC--SSEPCKNNGTCVDLTNR 949
L G CE+ +F C C G+SG + +INEC + C + C +
Sbjct: 1292 L------SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGS 1345
Query: 950 FFCNCEPEYHGPFCE-LDVNKCK--ISPCLDEENCVYRTDGYNCLCAPGYT--GINCEIN 1004
F C+C P + G + D+++C C +C Y CLC GYT G C +
Sbjct: 1346 FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC-TD 1404
Query: 1005 LDECLSEPCL-HDGVCIDGINHYTCDCKSGFF----GTHCETNANDCLSNPCLHGRCTEL 1059
LDEC L +G C++ Y C+C GF G CE L N C+ G C L
Sbjct: 1405 LDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNL 1464
Query: 1060 INEYPCSC----DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGY------ 1109
+ C C + D + C +N+C G C + + C CP +
Sbjct: 1465 PGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTR 1523
Query: 1110 ------TGAYCEKSI-------DNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQ 1156
C I D E+ + C G C P +
Sbjct: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
Query: 1157 FCEI------------------NINECSSSPCL-HGADCEDHINGYVCKCQPGW----SG 1193
+I +I+EC P L G C + + C+C G+
Sbjct: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDT 1643
Query: 1194 HHCENELEC-IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
C++ EC P C C TC+C P +M + G C D +RR C
Sbjct: 1644 RVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMD-MRRSLC 1695
Score = 249 bits (635), Expect = 4e-65
Identities = 298/1242 (23%), Positives = 482/1242 (38%), Gaps = 301/1242 (24%)
Query: 210 YCQELDACSFKPCK-NNGSCINKRENWDEQAYECVCHPPFT----GKNCSEIIGQCQ--P 262
+ ++++ C P +G C N + ++C C F +NC++I +C+ P
Sbjct: 1025 FFKDINECKMIPSLCTHGKCRNTIGS-----FKCRCDSGFALDSEERNCTDI-DECRISP 1078
Query: 263 HVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL-------LFWKRGICPNSSSA 315
+C G C N T F C+CDE + F + K C+ + L + G+C N+ +
Sbjct: 1079 DLCGRGQCVN-TPGDFECKCDEGYESGF--MMMKNCMDIDECQRDPLLCRGGVCHNTEGS 1135
Query: 316 YTYECPKG---SSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIF---TDLL- 366
Y ECP G S + + D++E L C NG C+ + C C+P + D L
Sbjct: 1136 YRCECPPGHQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQCACNPGYHSTPDRLF 1194
Query: 367 ------CKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFT----EKNCEKAIDHCKLLS 416
C + CE+F C E Y CSC GF +++C ID C+ +
Sbjct: 1195 CVDIDECSIMNGGCETF-------CTNSEGSYECSCQPGFALMPDQRSCTD-IDECE-DN 1245
Query: 417 INCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQ 476
N + C NI G ++ +C G + +K +++ + G C++
Sbjct: 1246 PNICDGGQCTNIPGEYRCLCYDGFMASE--DMKTCVDVNECDLNPNICLSGTCENT-KGS 1302
Query: 477 FEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICA 536
F +G++G +G+ CT+ +N+ E +C G +C
Sbjct: 1303 FICHCDMGYSGKKGK-------------TGCTD----INECEIGAHNC-----GKHAVCT 1340
Query: 537 NGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQEN---ECQHEAVCKDEINRPRCSCS 593
N + ++ C W G+ D+ N C A CK+ + RC C
Sbjct: 1341 N--------TAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCK 1392
Query: 594 LSYIG-RLCVVNVDYCLGNHSISVHGLCLAL--SHNCNC--SGLQRYERNICEIDTEDCK 648
Y G ++D C N ++ +G CL + C C + + CE D ++C
Sbjct: 1393 EGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE-DIDECS 1451
Query: 649 SASCKNGTTSTHLRGYFFRKCVPGFK----GTQCEIDIDECASHPCKNGATCIDQPGNYF 704
+ T +L G F +C G++ G C D++EC C++ PG+Y
Sbjct: 1452 LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYI 1510
Query: 705 CQCVPPFKV-------VDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQC 757
C C P F++ VD S C Y+ IR D D AC N + + C
Sbjct: 1511 CDCPPDFELNPTRVGCVDTRSGNC---YLDIRPRGDNGD---TACS-NEIGVGVSKASCC 1563
Query: 758 VCLSDWEGNFCE-----------------------------QESNECKMNP--CKNNSTC 786
L G CE ++ +EC+ P C+ C
Sbjct: 1564 CSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-C 1622
Query: 787 TDLYKSYRCECTSGW---TGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYT- 842
+ + S++C C +G+ +++NEC++ G C+ + G + C+CPP Y
Sbjct: 1623 INTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTV--GNYTCICPPDYMQ 1680
Query: 843 ---GQFC-HQRYNLCDLLHNPCRNNSTC---LALVDANQHCICREEFE---GKNCE---- 888
G C R +LC N +N TC L + C C K CE
Sbjct: 1681 VNGGNNCMDMRRSLC--YRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPI 1738
Query: 889 --------------------------IDVKDCLFLS--CQDYGDCEDMVNNFRCICRPGF 920
+D+ +C + C++ G C +MV +FRC C GF
Sbjct: 1739 PSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRCECPVGF 1797
Query: 921 SGS----LCEIEINECSSEP-CKNNGTCVDLTNRFFCNCEPEYHGPF---CELDVNKCKI 972
+ +CE +I+EC + P C+ N C++ + C+C+P Y C D N+C+
Sbjct: 1798 FYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCN-DRNECQE 1855
Query: 973 SPCL-DEENCVYRTDGYNCLCAPGYTGINCE---INLDECLSEPCLHDGVCIDGINHYTC 1028
P + C+ + CLC G+ + + ++++EC + C +G C + I + C
Sbjct: 1856 IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC-GNGTCRNTIGSFNC 1914
Query: 1029 DCKSGFFGTHCETNANDCL---------SNPCLHGRCTELINEYPCSCD------ADGTS 1073
C GF +H NDC+ N C +G+C + + C C+ DG +
Sbjct: 1915 RCNHGFILSH----NNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRT 1970
Query: 1074 TQCKIKINDCTSIP--CMNEGFCQKSAHGFTCICPRGYT--GAYCEKSIDNCA-EPELNS 1128
+ IN+C P C G CQ + CICP GY+ CE ID C EPE+ +
Sbjct: 1971 C---VDINECLLEPRKCA-PGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICA 2025
Query: 1129 VICLNGGICVDGPGHTFDCRCLPGF----SGQFC-EININECSSSPCLHGADCED----H 1179
+ G C + G +F C C GF SG+ C ++ ++ C + G C +
Sbjct: 2026 L-----GTCSNTEG-SFKCLCPEGFSLSSSGRRCQDLRMSYCYAK--FEGGKCSSPKSRN 2077
Query: 1180 INGYVCKCQ---PGWSGHHCE-----------------------------NELEC-IPNS 1206
+ C C GW G CE + EC P+
Sbjct: 2078 HSKQECCCALKGEGW-GDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDV 2136
Query: 1207 CVHELCMENEPGSTCLCTPGFM----------TCSIGLLCGD 1238
C H C+ + C C G++ CS+G CG+
Sbjct: 2137 CKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGN 2178
Score = 236 bits (601), Expect = 3e-61
Identities = 290/1200 (24%), Positives = 461/1200 (38%), Gaps = 242/1200 (20%)
Query: 155 GPSPCPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFS----GKY 210
G C + T + FC + +G + +Y C CQP F+ +
Sbjct: 1176 GKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 1235
Query: 211 CQELDACSFKP-CKNNGSCINKRENWDEQAYECVCHPPFTG----KNCSEIIGQC--QPH 263
C ++D C P + G C N Y C+C+ F K C + + +C P+
Sbjct: 1236 CTDIDECEDNPNICDGGQCTN-----IPGEYRCLCYDGFMASEDMKTCVD-VNECDLNPN 1289
Query: 264 VCFHGNCSNITSNSFICECDEQFSGP----------FCEVSAKPCVSLLFWKRGICPNSS 313
+C G C N T SFIC CD +SG CE+ A C K +C N++
Sbjct: 1290 ICLSGTCEN-TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNC-----GKHAVCTNTA 1343
Query: 314 SAYTYECPKGSSSQNGE-TDVSEFSLVPCQNGT-------DCIKISNDVMCICSPIFT-- 363
++ C G + TD+ E C NGT DC C+C +T
Sbjct: 1344 GSFKCSCSPGWIGDGIKCTDLDE-----CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGD 1398
Query: 364 DLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTE----KNCEKAIDHCKLLSINC 419
C + E+ L N C Y C C GF K CE ID C L +I
Sbjct: 1399 GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED-IDECSLPNICV 1457
Query: 420 LNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEY 479
C N+ G F+ C E
Sbjct: 1458 FGT--CHNLPGLFRCEC-----------------------------------------EI 1474
Query: 480 VWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGC 539
++L +G +D ++ NC VN P IC
Sbjct: 1475 GYELDRSGGNCTDVNECLDPTTCISGNC------VNTP-------------GSYIC---- 1511
Query: 540 SCLSEEDSQEYRYLCFLRWAGNMYLE--NTTDDQENECQHEAVCKDEINRPRCSCSLSYI 597
C + + R C +GN YL+ D+ + C +E +++ C CSL
Sbjct: 1512 DCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGV--GVSKASCCCSL--- 1566
Query: 598 GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKS--ASCKNG 655
G+ + C ++ LC G + + D ++C+ C+ G
Sbjct: 1567 GKAWGTPCEMCPAVNTSEYKILC------PGGEGFRPNPITVILEDIDECQELPGLCQGG 1620
Query: 656 TTSTHLRGYFFRKCVPGF---KGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFK 712
+ G F +C G+ + T+ D++EC + TC + GNY C C P +
Sbjct: 1621 -KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYM 1679
Query: 713 VVDGFS-------CLCNPGYVGIRCEQDIDDCILN------ACEH------NSTCKDLHL 753
V+G + LC Y D + + N C + N C+ +
Sbjct: 1680 QVNGGNNCMDMRRSLCYRNYYADNQTCD-GELLFNMTKKMCCCSYNIGRAWNKPCEQCPI 1738
Query: 754 ----SYQCVCLSDWEGNFCE------QESNECKMNP--CKNNSTCTDLYKSYRCECTSGW 801
+ +C S G + + +EC+ P C+ N C ++ S+RCEC G+
Sbjct: 1739 PSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCE-NGVCINMVGSFRCECPVGF 1797
Query: 802 TGQNCSEEINEC-DSDPCMNGGLCHES----TIPGQFVCLCPPLY----TGQFCHQRYNL 852
++++ C D D C NG +C + G + C C P Y TGQ C+ R N
Sbjct: 1798 F---YNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CNDR-NE 1852
Query: 853 CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE---IDVKDCLFLSCQDYGDCEDMV 909
C + N C ++ C+ V + +C+C F+ + + +D+ +C +C + G C + +
Sbjct: 1853 CQEIPNIC-SHGQCIDTV-GSFYCLCHTGFKTNDDQTMCLDINECERDACGN-GTCRNTI 1909
Query: 910 NNFRCICRPGF--SGSLCEIEINECSS---EPCKNNGTCVDLTNRFFCNCEPEYH----G 960
+F C C GF S + I+++EC+S C+ NG C++ F C C Y G
Sbjct: 1910 GSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDG 1968
Query: 961 PFCELDVNKCKISPCLDEENCVYRTDG-YNCLCAPGYTGIN--CEINLDECLSEPCLHD- 1016
C +D+N+C + P DG Y C+C PGY+ N CE ++DEC+ EP +
Sbjct: 1969 RTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICAL 2026
Query: 1017 GVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCL----HGRCT------ELINEYPCS 1066
G C + + C C GF + D + C G+C+ E C+
Sbjct: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCA 2086
Query: 1067 CDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPEL 1126
+G C++ C + P +E F Q +G I + +D C EP+
Sbjct: 2087 LKGEGWGDPCEL----CPTEP--DEAFRQICPYGSGIIVGPDDSAV----DMDECKEPD- 2135
Query: 1127 NSVICLNGGICVDGPGHTFDCRCLPGF--SGQFCEININECS-SSPCLHGADCEDHINGY 1183
+C +G C++ G ++ C C G+ +G C ++ +ECS +PC +G C++ I G+
Sbjct: 2136 ---VCKHGQ-CINTDG-SYRCECPFGYILAGNEC-VDTDECSVGNPCGNGT-CKNVIGGF 2188
Query: 1184 VCKCQPGWSG---HHCENELECIPNSCVHELCMENEPGS-TCLCTPGFMTCSIGLLCGDE 1239
C C+ G+ CE+ EC N + N GS C C G++ +C DE
Sbjct: 2189 ECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDE 2248
Score = 231 bits (590), Expect = 7e-60
Identities = 325/1318 (24%), Positives = 482/1318 (36%), Gaps = 352/1318 (26%)
Query: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQ----PPFSGKYCQELDACSFKPCKNNGSCI 229
C E+L+ G+G+CL+ Y C C P GK C+++D CS G+C
Sbjct: 1408 CSENLN---LCGNGQCLNAPGG--YRCECDMGFVPSADGKACEDIDECSLPNICVFGTCH 1462
Query: 230 NKRENWDEQAYECVCHPPF----TGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQ 285
N + C C + +G NC+++ P C GNC N T S+IC+C
Sbjct: 1463 NL-----PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVN-TPGSYICDCPPD 1516
Query: 286 FSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGT 345
F V CV S + Y P+G NG+T S V +
Sbjct: 1517 FELNPTRVG---CVDT---------RSGNCYLDIRPRGD---NGDTACSNEIGVGVSKAS 1561
Query: 346 DCIKISNDVMCICSPIFTDLLCKSIQTS--------------------------CESFP- 378
C + C +C ++ TS C+ P
Sbjct: 1562 CCCSLGKAWGTPCE------MCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG 1615
Query: 379 LRNNATCKKCEKDYPCSCISGFTEKNCEKAID---HCKLLSINCLNEEWCFNIIGRFKYV 435
L C + C C +G+ + D C+ I C+N +G + +
Sbjct: 1616 LCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI--CGPGTCYNTVGNYTCI 1673
Query: 436 CIPGCTK----NPCWFLK------NVYLIHQ------------HLCYCGVTFHGICQDKG 473
C P + N C ++ N Y +Q +C C G +K
Sbjct: 1674 CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNI-GRAWNKP 1732
Query: 474 PAQFEYVWQLGFAGSEGEKCQG-VIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK 532
Q FA G + G VID Y L P D + P
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGL-------------PVDIDECREIPG---- 1775
Query: 533 EICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENE----CQHEAVCKDEINRP 588
+C NG C++ S +R C + + N L D E + CQ A C +
Sbjct: 1776 -VCENGV-CINMVGS--FRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSY 1831
Query: 589 RCSCSLSY----IGRLCVVNVDYCLGNHSISVHGLCLAL--SHNCNC-SGLQRYERNICE 641
RC C Y G+ N C +I HG C+ S C C +G + +
Sbjct: 1832 RCDCKPGYRFTSTGQCNDRNE--CQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC 1889
Query: 642 IDTEDCKSASCKNGTTSTHLRGYFFRKCVPGF---KGTQCEIDIDECAS---HPCKNGAT 695
+D +C+ +C NGT + G F +C GF C ID+DECAS + C+NG
Sbjct: 1890 LDINECERDACGNGTCRNTI-GSFNCRCNHGFILSHNNDC-IDVDECASGNGNLCRNGQ- 1946
Query: 696 CIDQPGNYFCQCVPPFKV---------------------------VDG-FSCLCNPGYV- 726
CI+ G++ CQC ++V +DG + C+C PGY
Sbjct: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL 2006
Query: 727 -GIRCEQDIDDCI-------LNACEHNS------------------TCKDLHLSY----- 755
+CE DID+C+ L C + C+DL +SY
Sbjct: 2007 QNEKCE-DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKF 2065
Query: 756 ----------------QCVCLSDWEG-----NFCEQESNEC------------------- 775
+C C EG C E +E
Sbjct: 2066 EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA 2125
Query: 776 -KMNPCKN-----NSTCTDLYKSYRCECTSGWTGQNCSEEINEC-DSDPCMNGGLCHEST 828
M+ CK + C + SYRCEC G+ NEC D+D C G C T
Sbjct: 2126 VDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAG-----NECVDTDECSVGNPCGNGT 2180
Query: 829 ---IPGQFVCLCP------PLYTGQF---CHQRYNLCDLLHNPCRNNSTC---LALVDAN 873
+ G F C C P+ T + C Q LC + C + V
Sbjct: 2181 CKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLRE 2240
Query: 874 QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFS----GSLCEIEI 929
+C++E E CE DC + +C++++ + CIC PG+ G C ++
Sbjct: 2241 DRRMCKDEDE---CEEGKHDCT----EKQMECKNLIGTYMCICGPGYQRRPDGEGC-VDE 2292
Query: 930 NECSSEP--CKNNGTCVDLTNRFFCNCEPEYHGP--------------FCELDVNKCKIS 973
NEC ++P C+N G C++ + C C + F E+ N C+I
Sbjct: 2293 NECQTKPGICEN-GRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIG 2351
Query: 974 P-----------CLDE--------ENCVYR-TDGYNCLCAPGYTGINCEINLDEC--LSE 1011
C D E C ++ T + LC G + ++DEC + +
Sbjct: 2352 SSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHD 2411
Query: 1012 PCLHDGVCIDGINHYTCDCKSGFF----GTHCETNANDC--LSNPCLHGRCTELINEYPC 1065
C +G C++ Y C CK+G+ GT C + N+C PC + C Y C
Sbjct: 2412 VC-RNGECVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKPC-NFICKNTEGSYQC 2468
Query: 1066 SC------DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSID 1119
SC DG S CK +++C + + C + GFTC CP G+T + +
Sbjct: 2469 SCPKGYILQEDGRS--CK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDN 2525
Query: 1120 NCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFS----GQFCEININECSSSP-CLHGA 1174
N ++N +C + GIC + PG +F C C GFS G CE +++EC + C HG
Sbjct: 2526 NECTSDIN--LCGSKGICQNTPG-SFTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHG- 2580
Query: 1175 DCEDHINGYVCKCQPGWSGHH----CENELECI-PNSCVHELCMENEPGSTCLCTPGF 1227
C++ I GY C C G+ H+ C +E EC+ + C C C+C GF
Sbjct: 2581 -CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGF 2637
Score = 231 bits (588), Expect = 1e-59
Identities = 302/1251 (24%), Positives = 461/1251 (36%), Gaps = 291/1251 (23%)
Query: 213 ELDACSFKP--CKNNGSCINKRENWDEQAYECVCHPPF----TGKNCSEIIGQCQPH--V 264
+++ C+ P C N G C N R Y+C+C+ + TGKNC +I +C + +
Sbjct: 723 DINECALDPDICPN-GICENLRGT-----YKCICNSGYEVDSTGKNCVDI-NECVLNSLL 775
Query: 265 CFHGNCSNITSNSFICECDEQF--------SGPFCEVSAKPCVSLLFWKRGICPNSSSAY 316
C +G C N T SF+C C + F E + PC++ G+C NS ++
Sbjct: 776 CDNGQCRN-TPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCIN------GVCKNSPGSF 828
Query: 317 TYECPKGSSSQNGETDVSEFSLVPCQ------------NGTD-----CIKI-----SNDV 354
EC S+ +T E C NG C + S
Sbjct: 829 ICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCT 888
Query: 355 MCICSPI-------FTDLLCKSIQTSCESFP-LRNNATCKKCEKDYPCSCISGFTEKNCE 406
+C PI C+ I CE FP + N C + C C SG T
Sbjct: 889 LCQVDPICGKGYSRIKGTQCEDID-ECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Query: 407 KAIDHCKLLS--INCLNEEWCFNIIGRFKY-VCIPGCTKNPCWFLKNVYLI-------HQ 456
+ +L + + +EE I GR + C C+ W + ++
Sbjct: 948 RICLDIRLETCFLRYEDEECTLPIAGRHRMDACC--CSVGAAWGTEECEECPMRNTPEYE 1005
Query: 457 HLCYCGVTFHGICQDKGPAQFEYVWQLGFAGS--EGEKCQGVIDAYFFLAANCTEDATYV 514
LC G F G F+ + + S KC+ I ++ C D+ +
Sbjct: 1006 ELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF-----KCRCDSGFA 1060
Query: 515 NDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRW-AGNMYLENTTDDQEN 573
D E+ N + + ++C G C++ E + C + +G M ++N D +
Sbjct: 1061 LDSEERNCTDIDECRISPDLCGRG-QCVNTPGDFECK--CDEGYESGFMMMKNCMDI--D 1115
Query: 574 ECQHE------AVCKDEINRPRCSC----SLSYIGRLCVVNVDYCLGNHSISVHGLCLAL 623
ECQ + VC + RC C LS C+ +++ C + + +G C+ L
Sbjct: 1116 ECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACI-DINECELSAHLCPNGRCVNL 1174
Query: 624 --SHNCNCS-GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFK---GTQ 677
+ C C+ G + +D ++C + T T+ G + C PGF +
Sbjct: 1175 IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQR 1234
Query: 678 CEIDIDECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDID 735
DIDEC +P C +G C + PG Y C C Y G +D+
Sbjct: 1235 SCTDIDECEDNPNIC-DGGQCTNIPGEYRCLC-----------------YDGFMASEDMK 1276
Query: 736 DCI-LNACEHN------STCKDLHLSYQCVCLSDWEGNFCEQ---ESNECKMNP--CKNN 783
C+ +N C+ N TC++ S+ C C + G + + NEC++ C +
Sbjct: 1277 TCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKH 1336
Query: 784 STCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGG-LCHE----STIPGQFVCLCP 838
+ CT+ S++C C+ GW G I D D C NG +C + G + CLC
Sbjct: 1337 AVCTNTAGSFKCSCSPGWIGDG----IKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCK 1392
Query: 839 PLYTGQF--------CHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEF----EGKN 886
YTG C + NLC N CL C C F +GK
Sbjct: 1393 EGYTGDGFTCTDLDECSENLNLC--------GNGQCLN-APGGYRCECDMGFVPSADGKA 1443
Query: 887 CEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGF----SGSLCEIEINECSSEPCKNNGT 942
CE D+ +C + +G C ++ FRC C G+ SG C ++NEC +G
Sbjct: 1444 CE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCT-DVNECLDPTTCISGN 1501
Query: 943 CVDLTNRFFCNCEPEYH------------GPFCELDVNK--------------------- 969
CV+ + C+C P++ C LD+
Sbjct: 1502 CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKAS 1561
Query: 970 --CKI-----SPCLDEENC-VYRTDGYNCLCAPGYTGINCEI------NLDECLSEPCL- 1014
C + +PC E C T Y LC PG G ++DEC P L
Sbjct: 1562 CCCSLGKAWGTPC---EMCPAVNTSEYKILC-PGGEGFRPNPITVILEDIDECQELPGLC 1617
Query: 1015 HDGVCIDGINHYTCDCKSGFF---GTHCETNANDCLS-NPCLHGRCTELINEYPCSCDAD 1070
G CI+ + C C +G++ T + N+C + C G C + Y C C D
Sbjct: 1618 QGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPD 1677
Query: 1071 GTSTQCKIKINDCTSIPCMNEGFCQKS--AHGFTC-----------ICPRGYT-GAYCEK 1116
+++N + M C ++ A TC +C Y G K
Sbjct: 1678 ------YMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNK 1731
Query: 1117 SIDNCAEPELNSVICLNG------------------------------GICVDGPGHTFD 1146
+ C P + L G G+C++ G +F
Sbjct: 1732 PCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVG-SFR 1790
Query: 1147 CRCLPGFSGQ----FCEININECSSSP-CLHGADCEDHINGYVCKCQPGW---SGHHCEN 1198
C C GF CE +I+EC + P C A+C + Y C C+PG+ S C +
Sbjct: 1791 CECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCND 1849
Query: 1199 ELEC--IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD--EIRRITC 1245
EC IPN C H C++ CLC GF T +C D E R C
Sbjct: 1850 RNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC 1900
Score = 216 bits (549), Expect = 4e-55
Identities = 272/1117 (24%), Positives = 422/1117 (37%), Gaps = 269/1117 (24%)
Query: 263 HVCFHGNCSNITSNSFICECDEQFSGPF---C----EVSAKPCVSLLFWKRGICPNSSSA 315
++C +G C T S CEC++ F C E PC G C N+ +
Sbjct: 458 YLCQNGRCIP-TPGSCRCECNKGFQLDLRGECIDVDECEKNPCAG------GECINNQGS 510
Query: 316 YTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCE 375
YT +C G S T+ C++ +C++ N +C
Sbjct: 511 YTCQCRAGYQSTLTRTE--------CRDIDECLQ--NGRIC------------------- 541
Query: 376 SFPLRNNATCKKCEKDYPCSCISGF----TEKNCEKAIDHCKLLSINCLNEEWCFNIIGR 431
NN C + + C C +GF KNCE +D C + ++ CLN C N G
Sbjct: 542 -----NNGRCINTDGSFHCVCNAGFHVTRDGKNCED-MDECSIRNM-CLN-GMCINEDGS 593
Query: 432 FKYVCIPGCTKNPCWFLKNVYLIHQHLCYC---------GVTFHGIC-QDKGPAQFEYVW 481
FK +C PG + + YC G+ +G C G + E
Sbjct: 594 FKCICKPG------------FQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFP 641
Query: 482 QLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSC 541
L G +G C +D + + + C C P G + + C C
Sbjct: 642 GLA-VGLDGRVC---VDTH--MRSTCYGGY--------KRGQCIKPLFGA--VTKSECCC 685
Query: 542 LSEE-------------DSQEYRYLCF----LRWAGNMYLENTTDDQENECQHEAVCKDE 584
S E +S EY+ LC + AG+ E D + +C++
Sbjct: 686 ASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDP---DICPNGICENL 742
Query: 585 INRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDT 644
+C C+ Y VD S NC + N C +++
Sbjct: 743 RGTYKCICNSGY-------EVD-----------------STGKNCVDI-----NECVLNS 773
Query: 645 EDCKSASCKNGTTS---THLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPG 701
C + C+N S T +G+ ++ P K CE DIDEC S PC NG C + PG
Sbjct: 774 LLCDNGQCRNTPGSFVCTCPKGFIYK---PDLK--TCE-DIDECESSPCING-VCKNSPG 826
Query: 702 NYFCQC-----VPPFKV--VDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLS 754
++ C+C + P K ++ C + RCE +I+ L + C L +
Sbjct: 827 SFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLK----SQCCSSLGAA 882
Query: 755 YQCVC------------LSDWEGNFCEQESNECKMNP--CKNNSTCTDLYKSYRCECTSG 800
+ C S +G CE + +EC++ P CK N C + S++C+C SG
Sbjct: 883 WGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCK-NGLCVNTRGSFKCQCPSG 940
Query: 801 WTGQNCSEEINECDSDPCMNGGLCHESTIP-----GQFVCLCP--PLYTGQFCHQRYNLC 853
T + + C E T+P C C + + C + C
Sbjct: 941 MTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEE----C 996
Query: 854 DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFL-SCQDYGDCEDMVNNF 912
P RN L +E GK D+ +C + S +G C + + +F
Sbjct: 997 -----PMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF 1051
Query: 913 RCICRPGFSGSLCE---IEINECSSEP-CKNNGTCVDLTNRFFCNCEPEYHGPFCE---- 964
+C C GF+ E +I+EC P G CV+ F C C+ Y F
Sbjct: 1052 KCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 1111
Query: 965 LDVNKCKISPCLDEENCVYRTDG-YNCLCAPGY---TGINCEINLDEC-LSEPCLHDGVC 1019
+D+++C+ P L + T+G Y C C PG+ I+ I+++EC LS +G C
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRC 1171
Query: 1020 IDGINHYTCDCKSGFFGT-----------------HCE---------------------- 1040
++ I Y C C G+ T CE
Sbjct: 1172 VNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP 1231
Query: 1041 -----TNANDCLSNP--CLHGRCTELINEYPCSC-DADGTSTQCK--IKINDCTSIP--C 1088
T+ ++C NP C G+CT + EY C C D S K + +N+C P C
Sbjct: 1232 DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC 1291
Query: 1089 MNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCR 1148
++ G C+ + F C C GY+G + + E E+ + C +C + G +F C
Sbjct: 1292 LS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAG-SFKCS 1349
Query: 1149 CLPGFSGQFCE-ININECSSSP--CLHGADCEDHINGYVCKCQPGWS--GHHCENELECI 1203
C PG+ G + +++ECS+ C ADC++ + Y C C+ G++ G C + EC
Sbjct: 1350 CSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECS 1409
Query: 1204 P--NSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
N C + C+ G C C GF+ + G C D
Sbjct: 1410 ENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED 1446
Score = 196 bits (498), Expect = 3e-49
Identities = 281/1163 (24%), Positives = 429/1163 (36%), Gaps = 239/1163 (20%)
Query: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF----SGKYCQELDACSFKPCKNNGSCI 229
CQE C G GKC++ S + C C + + C +++ C G+C
Sbjct: 1610 CQELPG--LCQG-GKCINTFGS--FQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCY 1664
Query: 230 NKRENWDEQAYECVCHPPFT----GKNCSEIIGQCQPHVCFHG------NCS-----NIT 274
N N Y C+C P + G NC ++ + +C+ C N+T
Sbjct: 1665 NTVGN-----YTCICPPDYMQVNGGNNCMDM----RRSLCYRNYYADNQTCDGELLFNMT 1715
Query: 275 SNSFICECD--EQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETD 332
C + ++ P CE P +C + + + G D
Sbjct: 1716 KKMCCCSYNIGRAWNKP-CEQCPIPSTDEF---ATLCGSQRPGFVIDIYTGLP-----VD 1766
Query: 333 VSEFSLVP--CQNGTDCIKISNDVMCICSP--IFTD--LLCKSIQTSCESFPL-RNNATC 385
+ E +P C+NG CI + C C + D L+C+ I C++ P+ + NA C
Sbjct: 1767 IDECREIPGVCENGV-CINMVGSFRCECPVGFFYNDKLLVCEDID-ECQNGPVCQRNAEC 1824
Query: 386 KKCEKDYPCSCISGFTEKNCEKAIDHCKLLSI-NCLNEEWCFNIIGRFKYVCIPGCTKNP 444
Y C C G+ + + D + I N + C + +G F +C G N
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTND 1884
Query: 445 CWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLA 504
+ + C +G C++ F GF S C V D
Sbjct: 1885 ----DQTMCLDINECERDACGNGTCRNT-IGSFNCRCNHGFILSHNNDCIDV-DECASGN 1938
Query: 505 ANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEED----------------SQ 548
N + +N C +EG E+ +G +C+ +
Sbjct: 1939 GNLCRNGQCINTVGSFQCQC---NEGY-EVAPDGRTCVDINECLLEPRKCAPGTCQNLDG 1994
Query: 549 EYRYLCFLRWAGNMYLENTTDDQENECQHE------AVCKDEINRPRCSC----SLSYIG 598
YR +C ++ L+N + +EC E C + +C C SLS G
Sbjct: 1995 SYRCICPPGYS----LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2050
Query: 599 RLCV-VNVDYCLGNHSISVHGLCLALSHN---CNCSGLQRYERNICEIDTEDCKSASCKN 654
R C + + YC + +H+ C C+ + CE+ + A
Sbjct: 2051 RRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA---- 2106
Query: 655 GTTSTHLRGYFFRKCVPGFKGT-----QCEIDIDECASHP-CKNGATCIDQPGNYFCQCV 708
FR+ P G +D+DEC CK+G CI+ G+Y C+C
Sbjct: 2107 -----------FRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQ-CINTDGSYRCEC- 2153
Query: 709 PPFK-VVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGN- 766
PF ++ G C+ D D+C + N TCK++ ++C C +E
Sbjct: 2154 -PFGYILAGNECV------------DTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGP 2200
Query: 767 --FCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINEC-DSDPCMNGGL 823
CE + NEC NP C + Y SY C+C G+ E+ C D D C G
Sbjct: 2201 MMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYV---LREDRRMCKDEDECEEGK- 2255
Query: 824 CHEST--------IPGQFVCLCPPLY----TGQFCHQRYNLCDLLHNPCRNNSTCLALVD 871
H+ T + G ++C+C P Y G+ C N C C N CL
Sbjct: 2256 -HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDE-NECQTKPGIC-ENGRCLN-TR 2311
Query: 872 ANQHCICREEFEGKNCEIDVKD---------CLFLSCQDYGDCEDMVNNFRCICRPGFS- 921
+ C C + F + + D L CQ + V C C G
Sbjct: 2312 GSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW 2371
Query: 922 GSLCEI------------------------EINECS--SEPCKNNGTCVDLTNRFFCNCE 955
G CEI +I+EC + C+ NG CV+ + C C+
Sbjct: 2372 GPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCR-NGECVNDRGSYHCICK 2430
Query: 956 ----PEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY----TGINCEINLDE 1007
P+ G C +D+N+C +P C Y C C GY G +C+ +LDE
Sbjct: 2431 TGYTPDITGTSC-VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCK-DLDE 2488
Query: 1008 CLSEPCLHDGVCIDGINHYTCDCKSGFFGTH--CETNANDCLS--NPC-LHGRCTELINE 1062
C ++ +C++ I +TC C GF H C N N+C S N C G C
Sbjct: 2489 CATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDN-NECTSDINLCGSKGICQNTPGS 2547
Query: 1063 YPCSC----DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
+ C C D T + C+ +++C G CQ G+ C CP+GY Y
Sbjct: 2548 FTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHY---QW 2602
Query: 1119 DNCAEPELNSVICLNGGICVDGPGH----TFDCRCLPGFS-GQF---CEININECSS--S 1168
+ C + CL+ IC H ++ C C GF QF C+ +INEC S +
Sbjct: 2603 NQCVDEN----ECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQA 2657
Query: 1169 PCLHGADCEDHINGYVCKCQPGW 1191
PC +G C + GY+C C PG+
Sbjct: 2658 PCSYG--CSNTEGGYLCGCPPGY 2678
Score = 118 bits (296), Expect = 8e-26
Identities = 135/552 (24%), Positives = 202/552 (36%), Gaps = 110/552 (19%)
Query: 755 YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC-SEEINEC 813
Y C W+ N+C + C+++ + C C SG +C S I C
Sbjct: 63 YNAYCCPGWK---TLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
Query: 814 DSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN 873
+ CMNGG C + CLC Y G C Q + + C N C+ A
Sbjct: 120 NIR-CMNGGSCSDDH------CLCQKGYIGTHCGQ-----PVCESGCLNGGRCV----AP 163
Query: 874 QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG-----SLCEIE 928
C C F G CE D + G C +++N +C+ SG +LC
Sbjct: 164 NRCACTYGFTGPQCERDYRT---------GPCFTVISN--QMCQGQLSGIVCTKTLCCAT 212
Query: 929 INECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE-ENCVYRTDG 987
+ PC+ R F P C+ DV++C+ P L + NC+
Sbjct: 213 VGRAWGHPCEMCPAQPHPCRRGFI---PNIRTGACQ-DVDECQAIPGLCQGGNCINTVGS 268
Query: 988 YNCLCAPGY----TGINCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSGFF----GTH 1038
+ C C G+ CE ++DEC + P + G C + ++ Y C C GF+ GT
Sbjct: 269 FECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTR 327
Query: 1039 CETNANDCLSNPCLHGRCT----ELINEYPCSCDADG--------TSTQCKIK----IND 1082
C +GRC+ + I + C CDA C I+ N
Sbjct: 328 CIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 387
Query: 1083 CTSIPCMNEGFCQKSAHGFTCI-----CPRGYTGA-----------YCEKS--------- 1117
S+P + G + I P G+ Y S
Sbjct: 388 LCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPV 447
Query: 1118 --IDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQF---CEININECSSSPCLH 1172
D C +L +C NG C+ PG + C C GF C I+++EC +PC
Sbjct: 448 NVTDYC---QLVRYLCQNGR-CIPTPG-SCRCECNKGFQLDLRGEC-IDVDECEKNPCA- 500
Query: 1173 GADCEDHINGYVCKCQPGWSG----HHCENELECIPNS--CVHELCMENEPGSTCLCTPG 1226
G +C ++ Y C+C+ G+ C + EC+ N C + C+ + C+C G
Sbjct: 501 GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAG 560
Query: 1227 FMTCSIGLLCGD 1238
F G C D
Sbjct: 561 FHVTRDGKNCED 572
Score = 98.2 bits (243), Expect = 1e-19
Identities = 175/727 (24%), Positives = 259/727 (35%), Gaps = 203/727 (27%)
Query: 159 CPLGLRLNV-----TVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF----SGK 209
CP G + V V C+E + C HG+C++ S Y C C PF +G
Sbjct: 2111 CPYGSGIIVGPDDSAVDMDECKEP---DVCK-HGQCINTDGS--YRCEC--PFGYILAGN 2162
Query: 210 YCQELDACSF-KPCKNNGSCINKRENWDEQAYECVCHPPFTG---KNCSEIIGQCQPHVC 265
C + D CS PC NG+C N +EC C F C +I Q +
Sbjct: 2163 ECVDTDECSVGNPC-GNGTCKNV-----IGGFECTCEEGFEPGPMMTCEDINECAQNPLL 2216
Query: 266 FHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSS 325
C N T S+ C+C P +L R +C + EC
Sbjct: 2217 CAFRCVN-TYGSYECKC--------------PVGYVLREDRRMCKDED-----EC----- 2251
Query: 326 SQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIF---TDLLCKSIQTSCESFP-LRN 381
+ G+ D +E + +C + MCIC P + D + C++ P +
Sbjct: 2252 -EEGKHDCTEKQM-------ECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE 2303
Query: 382 NATCKKCEKDYPCSCISGFT-EKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVC-IPG 439
N C Y C C GFT N ++ +D+ E +CF + + +C I
Sbjct: 2304 NGRCLNTRGSYTCECNDGFTASPNQDECLDN---------REGYCFTEV--LQNMCQIGS 2352
Query: 440 CTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKC--QGVI 497
+NP VT C D G W G E C QG +
Sbjct: 2353 SNRNP------------------VTKSECCCDGGRG-----W-----GPHCEICPFQGTV 2384
Query: 498 DAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLR 557
A+ L C ++ + D + C H ++C NG C+++ S Y C +
Sbjct: 2385 -AFKKL---CPHGRGFMTNGADID-ECKVIH----DVCRNG-ECVNDRGS----YHCICK 2430
Query: 558 WAGNMYLENTTDDQENECQH-----EAVCKDEINRPRCSCSLSYI----GRLCVVNVDYC 608
+ T+ NEC +CK+ +CSC YI GR C ++D C
Sbjct: 2431 TGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC-KDLDEC 2489
Query: 609 LGNHSISVHGLCLAL--SHNCNCSGLQRYERNICEIDTEDCKS--ASCKNGTTSTHLRGY 664
+ LC+ C C C ID +C S C + + G
Sbjct: 2490 -ATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSC-IDNNECTSDINLCGSKGICQNTPGS 2547
Query: 665 FFRKCVPGFK----GTQCEIDIDEC-ASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSC 719
F +C GF G+ CE D+DEC +H C++G CQ ++ G+ C
Sbjct: 2548 FTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHG-----------CQ-----NIIGGYRC 2590
Query: 720 LCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP 779
C GY + N C + C H+
Sbjct: 2591 SCPQGY--------LQHYQWNQCVDENECLSAHIC------------------------- 2617
Query: 780 CKNNSTCTDLYKSYRCECTSGWTGQNCS---EEINECDS--DPCMNGGLCHESTIPGQFV 834
++C + SY+C C +G+ + S ++INEC S PC G C S G ++
Sbjct: 2618 --GGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG--C--SNTEGGYL 2671
Query: 835 CLCPPLY 841
C CPP Y
Sbjct: 2672 CGCPPGY 2678
Score = 93.2 bits (230), Expect = 4e-18
Identities = 143/602 (23%), Positives = 218/602 (36%), Gaps = 129/602 (21%)
Query: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPF----TGKNCSEIIGQCQPHVCF 266
C+E D C +G CIN + +Y C C PF G C + + C
Sbjct: 2131 CKEPDVCK------HGQCINT-----DGSYRCEC--PFGYILAGNECVDTDECSVGNPCG 2177
Query: 267 HGNCSNITSNSFICECDEQFS-GPF--CEVSAKPCVSLLFWKRGICPNSSSAYTYECPKG 323
+G C N+ F C C+E F GP CE C C N+ +Y +CP G
Sbjct: 2178 NGTCKNVIGG-FECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVG 2235
Query: 324 SSSQNG-----ETDVSEFSLVPC-QNGTDCIKISNDVMCICSPIFT---DLLCKSIQTSC 374
+ + D E C + +C + MCIC P + D + C
Sbjct: 2236 YVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENEC 2295
Query: 375 ESFP-LRNNATCKKCEKDYPCSCISGFTEK-NCEKAIDHCKLLSINCLNEEWCFNIIGRF 432
++ P + N C Y C C GFT N ++ +D+ E +CF +
Sbjct: 2296 QTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDN---------REGYCFTEV--L 2344
Query: 433 KYVC-IPGCTKNPCWFLKNVYLIHQHLCYCGVTFHG----ICQDKGPAQFEYVWQLGFA- 486
+ +C I +NP + C G G IC +G F+ + G
Sbjct: 2345 QNMCQIGSSNRNP--------VTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGF 2396
Query: 487 ---GSEGEKCQGVIDAYFFLAANCTEDATYVN-------DPEDNNSSCWFPHEGTKE--- 533
G++ ++C+ + D C D + P+ +SC +E +
Sbjct: 2397 MTNGADIDECKVIHDVC--RNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKP 2454
Query: 534 ---ICANG-----CSC----LSEEDSQEYR-------------YLCFLRWAG-------- 560
IC N CSC + +ED + + +LC G
Sbjct: 2455 CNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPG 2514
Query: 561 -NMYLENTTDDQE-----NECQHEAVCKDEINRPRCSC----SLSYIGRLCVVNVDYCLG 610
+ + D+ E N C + +C++ C C SL G C +VD C G
Sbjct: 2515 FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEG 2573
Query: 611 NHSISVHGLCLALSHNCNCSG--LQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRK 668
NH + + C+C LQ Y+ N C +D +C SA G + + G +
Sbjct: 2574 NHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQC-VDENECLSAHICGGASCHNTLGSYKCM 2632
Query: 669 CVPGFKGTQ----CEIDIDECASH--PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCN 722
C GF+ Q C+ DI+EC S PC G C + G Y C C P + + C+
Sbjct: 2633 CPAGFQYEQFSGGCQ-DINECGSAQAPCSYG--CSNTEGGYLCGCPPGYFRIGQGHCVSG 2689
Query: 723 PG 724
G
Sbjct: 2690 MG 2691
Score = 86.7 bits (213), Expect = 3e-16
Identities = 64/211 (30%), Positives = 95/211 (45%), Gaps = 25/211 (11%)
Query: 1051 CLHGRCTELINEYPCSCDAD---GTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPR 1107
C +GRC C C+ +C I +++C PC G C + +TC C
Sbjct: 460 CQNGRCIPTPGSCRCECNKGFQLDLRGEC-IDVDECEKNPCAG-GECINNQGSYTCQCRA 517
Query: 1108 GYTGAYCE---KSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF----SGQFCEI 1160
GY + ID C + N IC N G C++ G +F C C GF G+ CE
Sbjct: 518 GYQSTLTRTECRDIDECLQ---NGRIC-NNGRCINTDG-SFHCVCNAGFHVTRDGKNCE- 571
Query: 1161 NINECS-SSPCLHGADCEDHINGYVCKCQPGWS----GHHCENELEC-IPNSCVHELCME 1214
+++ECS + CL+G C + + C C+PG+ G +C++ EC P C++ C+
Sbjct: 572 DMDECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVN 630
Query: 1215 NEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
+ C C PG G +C D R TC
Sbjct: 631 TDGSYRCECFPGLAVGLDGRVCVDTHMRSTC 661
Score = 78.6 bits (192), Expect = 9e-14
Identities = 74/294 (25%), Positives = 109/294 (37%), Gaps = 48/294 (16%)
Query: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGI--NHYTCDCKSGFFGTHCETNAND 1045
YN C PG+ + ++C+ C H C DG C C SG C + +
Sbjct: 63 YNAYCCPGWKTLP---GGNQCIVPICRHS--CGDGFCSRPNMCTCPSGQIAPSCGSRSIQ 117
Query: 1046 CLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCIC 1105
+ C++G ++ C C T C + C S C+N G C C C
Sbjct: 118 HCNIRCMNGGSC---SDDHCLCQKGYIGTHCGQPV--CES-GCLNGGRCVAPNR---CAC 168
Query: 1106 PRGYTGAYCEKSI----------DNCAEPELNSVICLN-----------GGICVDGPGHT 1144
G+TG CE+ + + +L+ ++C G C P
Sbjct: 169 TYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQP 228
Query: 1145 FDCR--CLPGFSGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGWS----GHHCE 1197
CR +P C+ +++EC + P L G +C + + + CKC G CE
Sbjct: 229 HPCRRGFIPNIRTGACQ-DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCE 287
Query: 1198 NELEC--IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPI 1249
+ EC IP C C C C PGF T G C D +R C T +
Sbjct: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID-VRPGYCYTAL 340
Score = 58.5 bits (140), Expect = 1e-07
Identities = 88/381 (23%), Positives = 125/381 (32%), Gaps = 112/381 (29%)
Query: 669 CVPGFK----GTQCEIDI--DECASHPCKNGATCIDQPGNYFCQCVPP------FKVVDG 716
C PG+K G QC + I C C C G C + ++G
Sbjct: 67 CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNG 126
Query: 717 FSC-----LCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQE 771
SC LC GY+G C Q + CE
Sbjct: 127 GSCSDDHCLCQKGYIGTHCGQPV-------CE---------------------------- 151
Query: 772 SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPG 831
+ C N C RC CT G+TG C + ++ +C + + G
Sbjct: 152 ------SGCLNGGRCV---APNRCACTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSG 201
Query: 832 QFVC---LCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE 888
VC LC G+ +C +PCR A Q
Sbjct: 202 -IVCTKTLCCAT-VGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQ-------------- 245
Query: 889 IDVKDCLFLS--CQDYGDCEDMVNNFRCICRPGFS----GSLCEIEINECSSEP--CKNN 940
DV +C + CQ G+C + V +F C C G CE +I+ECS+ P C+
Sbjct: 246 -DVDECQAIPGLCQG-GNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICE-G 301
Query: 941 GTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGIN 1000
G C + + +FC C P ++ SP D C+ GY C T
Sbjct: 302 GECTNTVSSYFCKCPPGFY------------TSP--DGTRCIDVRPGY---CYTALTNGR 344
Query: 1001 CEINLDECLS--EPCLHDGVC 1019
C L + ++ + C G C
Sbjct: 345 CSNQLPQSITKMQCCCDAGRC 365
Score = 45.4 bits (106), Expect = 9e-04
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLN--N 2919
G KG + D + G + C CT +F C C P W G+ C C N +
Sbjct: 1313 GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTH 1372
Query: 2920 LCLHQSLCIPDQSFSYSCLCTLGWVG 2945
+C + C + SY CLC G+ G
Sbjct: 1373 MCSQHADC-KNTMGSYRCLCKEGYTG 1397
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 15/79 (18%)
Query: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVP 2388
++I++C++ C N G+C D+ C C + Y G C CE+ C NG CV
Sbjct: 114 RSIQHCNIR------CMNGGSCSDDH----CLCQKGYIGTHCGQPVCESG-CLNGGRCVA 162
Query: 2389 KSGTDIVCLCPYGRSGPLC 2407
+ C C YG +GP C
Sbjct: 163 PNR----CACTYGFTGPQC 177
Score = 43.1 bits (100), Expect = 0.004
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGW--KGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
CG C + S C+C+ GW G CT+ D + H CS+ A C + Y
Sbjct: 1333 CGKHAVCTNTAGSFKCSCSPGWIGDGIKCTD----LDECSNGTHMCSQHADCKNTMGSYR 1388
Query: 2677 CFCPLGTTG 2685
C C G TG
Sbjct: 1389 CLCKEGYTG 1397
Score = 41.6 bits (96), Expect = 0.013
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 2622 GGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP--EHDPPHHCSRGATCISLPHGYTCFC 2679
GG CI + S C C TG+ + E CD E + P C G TC + YTC C
Sbjct: 1619 GGKCINTFGSFQCRCPTGY---YLNEDTRVCDDVNECETPGICGPG-TCYNTVGNYTCIC 1674
Query: 2680 P 2680
P
Sbjct: 1675 P 1675
Score = 40.4 bits (93), Expect = 0.028
Identities = 57/259 (22%), Positives = 83/259 (32%), Gaps = 73/259 (28%)
Query: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
C+ S FCS C + SC + + C+ + C N GSC +
Sbjct: 85 CRHSCGDGFCSRPNMCTCPSGQIAPSCGSR---------SIQHCNIR-CMNGGSCSDDH- 133
Query: 234 NWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEV 293
C+C + G +C + + C+ G C + N C C F+GP CE
Sbjct: 134 --------CLCQKGYIGTHCGQPV--CESGCLNGGRC--VAPNR--CACTYGFTGPQCER 179
Query: 294 SAK--PCVSLLF-------------WKRGICPNSSSAYTYECPKGSSSQN---------- 328
+ PC +++ K C A+ + C + +
Sbjct: 180 DYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNI 239
Query: 329 ---GETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNA 383
DV E +P CQ G +CI C C P L N
Sbjct: 240 RTGACQDVDECQAIPGLCQGG-NCINTVGSFECKC-PAGHKL----------------NE 281
Query: 384 TCKKCEKDYPCSCISGFTE 402
+KCE CS I G E
Sbjct: 282 VSQKCEDIDECSTIPGICE 300
Score = 39.3 bits (90), Expect = 0.062
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 11/68 (16%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCISLPHG 2674
CG+ G C + S C C G+ GS C E V C+ H C G C ++ G
Sbjct: 2535 CGSKGICQNTPGSFTCECQRGFSLDQTGSSC-EDVDECEGN----HRCQHG--CQNIIGG 2587
Query: 2675 YTCFCPLG 2682
Y C CP G
Sbjct: 2588 YRCSCPQG 2595
Score = 38.1 bits (87), Expect = 0.14
Identities = 42/158 (26%), Positives = 61/158 (38%), Gaps = 31/158 (19%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWA---GNTCNQSVSCLN---NLCLH 2923
++ +C+ ACG TCRN T+ +F+CRC + N C C + NLC
Sbjct: 1891 DINECERDACGNGTCRN----TIG--SFNCRCNHGFILSHNNDCIDVDECASGNGNLC-R 1943
Query: 2924 QSLCIPDQSFSYSCLCTLGWV----GRYC---------ENKTSFSTAKFMGNSYIKYIDP 2970
CI + S+ C C G+ GR C K + T + + SY P
Sbjct: 1944 NGQCI-NTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPP 2002
Query: 2971 NYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDF 3008
Y ++N + I E I +G N E F
Sbjct: 2003 GYSLQNEKCEDI----DECVEEPEICALGTCSNTEGSF 2036
Score = 37.4 bits (85), Expect = 0.24
Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 40/182 (21%)
Query: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-------LDACSFKPCKNNG 226
C + + C G+C++ C C F+G C+ S + C+
Sbjct: 145 CGQPVCESGCLNGGRCVAPN-----RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQL 199
Query: 227 S---------CINKRENWDEQAYECVCHP--------PFTGKNCSEIIGQCQ--PHVCFH 267
S C W C P P + + +CQ P +C
Sbjct: 200 SGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG 259
Query: 268 GNCSNITSNSFICECDEQFSGPFCEVSAK-----PCVSLL-FWKRGICPNSSSAYTYECP 321
GNC N T SF C+C EVS K C ++ + G C N+ S+Y +CP
Sbjct: 260 GNCIN-TVGSFECKCPAGHK--LNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCP 316
Query: 322 KG 323
G
Sbjct: 317 PG 318
Score = 37.4 bits (85), Expect = 0.24
Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 12/88 (13%)
Query: 2599 HPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDP 2654
H N V +C + +L C NG CI + S C C G++ G C + ++ C
Sbjct: 1924 HNNDCIDVDECASGNGNL--CRNG-QCINTVGSFQCQCNEGYEVAPDGRTCVD-INECLL 1979
Query: 2655 EHDPPHHCSRGATCISLPHGYTCFCPLG 2682
E P C+ G TC +L Y C CP G
Sbjct: 1980 E---PRKCAPG-TCQNLDGSYRCICPPG 2003
Score = 37.0 bits (84), Expect = 0.31
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 10/66 (15%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW 2943
C NGG C+ + C C + G C Q V + CL+ C+ C CT G+
Sbjct: 123 CMNGGSCSDD----HCLCQKGYIGTHCGQPVC--ESGCLNGGRCVAPNR----CACTYGF 172
Query: 2944 VGRYCE 2949
G CE
Sbjct: 173 TGPQCE 178
Score = 36.2 bits (82), Expect = 0.53
Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 10/88 (11%)
Query: 320 CPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPL 379
CP G + + + + + C NG C +D C+C + C Q CES L
Sbjct: 102 CPSGQIAPSCGSRSIQHCNIRCMNGGSC----SDDHCLCQKGYIGTHCG--QPVCESGCL 155
Query: 380 RNNATCKKCEKDYPCSCISGFTEKNCEK 407
+C C+C GFT CE+
Sbjct: 156 NGG----RCVAPNRCACTYGFTGPQCER 179
Score = 36.2 bits (82), Expect = 0.53
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 1/66 (1%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
CS+M G C S S C+C G+ + + D D P+ C G C ++P
Sbjct: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GGQCTNIPG 1259
Query: 2674 GYTCFC 2679
Y C C
Sbjct: 1260 EYRCLC 1265
Score = 35.8 bits (81), Expect = 0.69
Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 5/87 (5%)
Query: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
P A + V +C A P GG CI + S C C G K + ++ D
Sbjct: 237 PNIRTGACQDVDECQAIPGLCQ----GGNCINTVGSFECKCPAGHKLNEVSQKCEDIDEC 292
Query: 2656 HDPPHHCSRGATCISLPHGYTCFCPLG 2682
P C G C + Y C CP G
Sbjct: 293 STIPGIC-EGGECTNTVSSYFCKCPPG 318
Score = 35.8 bits (81), Expect = 0.69
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
Query: 2872 GDC-DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAG----NTCNQSVSCLNN--LCLHQ 2924
G+C D C N C GGEC N +++C+C + C CL N +C +
Sbjct: 486 GECIDVDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC-NN 543
Query: 2925 SLCIPDQSFSYSCLCTLGW----VGRYCEN 2950
CI + S+ C+C G+ G+ CE+
Sbjct: 544 GRCI-NTDGSFHCVCNAGFHVTRDGKNCED 572
Score = 35.4 bits (80), Expect = 0.90
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 7/69 (10%)
Query: 2342 HLCRNNGTCISDNENLFCECPRLYS----GKLCQFASCENNPCGNGATCVPKSGTDIVCL 2397
+LC+N G CI + CEC + + G+ CE NPC G C+ G+ C
Sbjct: 458 YLCQN-GRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGS-YTCQ 514
Query: 2398 CPYGRSGPL 2406
C G L
Sbjct: 515 CRAGYQSTL 523
Score = 35.4 bits (80), Expect = 0.90
Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 7/77 (9%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C +PC+ GG CI + S C C G++ + D C+ G
Sbjct: 491 VDECEKNPCA------GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNG 544
Query: 2666 ATCISLPHGYTCFCPLG 2682
CI+ + C C G
Sbjct: 545 -RCINTDGSFHCVCNAG 560
Score = 35.4 bits (80), Expect = 0.90
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKG----SFCTETVSTCDPEHDPPHH 2661
V +C +P + GTC + S C+C G+ G + CT+ ++ C+ H+
Sbjct: 1281 VNECDLNPNICLS----GTCENTKGSFICHCDMGYSGKKGKTGCTD-INECEIG---AHN 1332
Query: 2662 CSRGATCISLPHGYTCFCPLGTTG 2685
C + A C + + C C G G
Sbjct: 1333 CGKHAVCTNTAGSFKCSCSPGWIG 1356
Score = 35.0 bits (79), Expect = 1.2
Identities = 29/84 (34%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLY--SGKLC-QFASCE-NNPCGNGAT 2385
+++ C P H G CI+ + + CECP Y +G C C NPCGNG T
Sbjct: 2127 DMDECKEPDVCKH-----GQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNG-T 2180
Query: 2386 CVPKSGTDIVCLCPYG-RSGPLCT 2408
C G C C G GP+ T
Sbjct: 2181 CKNVIG-GFECTCEEGFEPGPMMT 2203
Score = 34.3 bits (77), Expect = 2.0
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 2614 CSLMK--CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
C L++ C NG CI + S C C G++ E + + E +P C+ G CI+
Sbjct: 453 CQLVRYLCQNG-RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP---CA-GGECINN 507
Query: 2672 PHGYTCFCPLG 2682
YTC C G
Sbjct: 508 QGSYTCQCRAG 518
Score = 34.3 bits (77), Expect = 2.0
Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 6/89 (6%)
Query: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLNNLCLHQS 2925
G D D + G + C +C ++ C C + G+ TC C NL L +
Sbjct: 1358 GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGN 1417
Query: 2926 LCIPDQSFSYSCLCTLGWV----GRYCEN 2950
+ Y C C +G+V G+ CE+
Sbjct: 1418 GQCLNAPGGYRCECDMGFVPSADGKACED 1446
Score = 33.9 bits (76), Expect = 2.6
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 14/92 (15%)
Query: 2327 HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGA-- 2384
+G +I+ C V H +CRN G C++D + C C Y+ + + + N C
Sbjct: 2399 NGADIDECKV---IHDVCRN-GECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKP 2454
Query: 2385 ---TCVPKSGTDIVCLCPYG----RSGPLCTD 2409
C G+ C CP G G C D
Sbjct: 2455 CNFICKNTEGS-YQCSCPKGYILQEDGRSCKD 2485
Score = 33.5 bits (75), Expect = 3.4
Identities = 42/209 (20%), Positives = 65/209 (31%), Gaps = 39/209 (18%)
Query: 259 QCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTY 318
QC +C H S +C C P C + ++ G C +
Sbjct: 79 QCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL--- 135
Query: 319 ECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFP 378
C KG + V E C NG C+ + C C+ FT C+ + F
Sbjct: 136 -CQKGYIGTHCGQPVCESG---CLNGGRCVAPNR---CACTYGFTGPQCERDYRTGPCFT 188
Query: 379 LRNNATCK------KCEKDYPCSCISGFTEKNCE----------------------KAID 410
+ +N C+ C K C+ + CE + +D
Sbjct: 189 VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVD 248
Query: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPG 439
C+ + C C N +G F+ C G
Sbjct: 249 ECQAIPGLCQGGN-CINTVGSFECKCPAG 276
Score = 33.5 bits (75), Expect = 3.4
Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDW---AGNTCNQSVSC--LNNLCLHQSLCIPDQSFSYSCL 2938
C+ EC ++ C C P + + CN C + N+C H CI D S+ CL
Sbjct: 1818 CQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCI-DTVGSFYCL 1875
Query: 2939 CTLGW 2943
C G+
Sbjct: 1876 CHTGF 1880
Score = 33.1 bits (74), Expect = 4.4
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 7/106 (6%)
Query: 2597 EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH 2656
EG+ G + +L CGNG C+ + C C G+ S + D E
Sbjct: 1393 EGYTGDGFTCTDLDECSENLNLCGNG-QCLNAPGGYRCECDMGFVPSADGKACEDID-EC 1450
Query: 2657 DPPHHCSRGATCISLPHGYTCFCPLG----TTGIYCEQALSISDPS 2698
P+ C G TC +LP + C C +G +G C DP+
Sbjct: 1451 SLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT 1495
Score = 33.1 bits (74), Expect = 4.4
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 10/71 (14%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCI 2669
CSL GTC C C G++ G CT+ DP C G C+
Sbjct: 1450 CSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT-----CISG-NCV 1503
Query: 2670 SLPHGYTCFCP 2680
+ P Y C CP
Sbjct: 1504 NTPGSYICDCP 1514
Score = 32.7 bits (73), Expect = 5.8
Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 6/78 (7%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-ETVSTCDPEHDPPHHCSR 2664
+ +C SP CG G C+ + C C G++ F + D P C R
Sbjct: 1071 IDECRISPDL---CGRG-QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC-R 1125
Query: 2665 GATCISLPHGYTCFCPLG 2682
G C + Y C CP G
Sbjct: 1126 GGVCHNTEGSYRCECPPG 1143
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 246 bits (627), Expect = 3e-64
Identities = 306/1179 (25%), Positives = 445/1179 (37%), Gaps = 255/1179 (21%)
Query: 197 TYSCHCQPPFS----GKYCQELDACSFKP--CKNNGSCINKRENWDEQAYECVCHPPFTG 250
+Y C C +S G+ C ++D C P C + G C N + C+C+ F
Sbjct: 1176 SYRCSCGQGYSLMPDGRACADVDECEENPRVC-DQGHCTNM-----PGGHRCLCYDGFMA 1229
Query: 251 ----KNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQF----------SGPFCEVS 294
+ C ++ +C PH+C HG+C N T SF+C C + CEV
Sbjct: 1230 TPDMRTCVDV-DECDLNPHICLHGDCEN-TKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 295 AKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGET-DVSEFSLVP--CQNGTDCIKIS 351
C S C N +++ C G E D+ E C DC+ +
Sbjct: 1288 GHNCDS-----HASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 352 NDVMCICSPIFTD--LLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA- 408
C C F C+ E+ L +N C Y C C GF +A
Sbjct: 1343 GSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRAC 1402
Query: 409 --IDHCKLLSINCLNEEWCFNIIGRFKYVCIPG---------CTK-NPCWFLKNVYLIHQ 456
+D C ++ C N+ G F+ +C G CT N C N
Sbjct: 1403 QDVDECAQGNLCAFGS--CENLPGMFRCICNGGYELDRGGGNCTDINECADPVN------ 1454
Query: 457 HLCYCGVTFH--GICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYV 514
C GV + G P FE L +G G +D A NC +
Sbjct: 1455 --CINGVCINTPGSYLCSCPQDFE----LNPSGV------GCVDTR---AGNCFLET--- 1496
Query: 515 NDPEDNNSSCW--FPHEGTKEICA--------NGCSCLSEEDSQEYRYLC-----FLRWA 559
+D D+ SC T+ C N C ++ EYR LC F
Sbjct: 1497 HDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNR 1556
Query: 560 GNMYLENTTDDQE--NECQHEAVCKDEINRPRCSCS----LSYIGRLCVVNVDYCLGNHS 613
+ LE+ + QE CQ C + +C C LS R+C ++D C +
Sbjct: 1557 ITVILEDIDECQELPGLCQG-GDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSG 1614
Query: 614 ISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASC---KNGTTSTHLRGYFFRKC- 669
I G C N C Y + + D + + C NGT L RK
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMC 1674
Query: 670 --------------------------------VPGFKG---TQCEIDIDECASHP--CKN 692
PGF T +DIDEC P C N
Sbjct: 1675 CCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICAN 1734
Query: 693 GATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL--NACEHNSTCKD 750
G CI+Q G++ C+C F N + + CE D+D+C + C+ N+ C +
Sbjct: 1735 GI-CINQIGSFRCECPAGF----------NYNSILLACE-DVDECGSRESPCQQNADCIN 1782
Query: 751 LHLSYQCVCLSDWE---GNFCEQESNECKMNP--CKNNSTCTDLYKSYRCECTSGWTG-- 803
+ SY+C C ++ G C NEC+ P C + C D SY C C G+
Sbjct: 1783 IPGSYRCKCTRGYKLSPGGACVGR-NECREIPNVCSHGD-CMDTEGSYMCLCHRGFQASA 1840
Query: 804 -QNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQF---CHQRYNLCDLLHNP 859
Q +I+ECD PC NG I G + CLC P + C L+
Sbjct: 1841 DQTLCMDIDECDRQPCGNGTC---KNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQV 1897
Query: 860 CRNNSTCLALVDANQHCICREEFE----GKNCEIDVKDCLFLS--CQDYGDCEDMVNNFR 913
CR CL + HC+C++ FE GKNC +D +CL L+ C G C+++ +FR
Sbjct: 1898 CRFGH-CLNTA-GSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCLP-GTCQNLEGSFR 1953
Query: 914 CICRPGFS--GSLCEIEINECSSEP--CKNNGTCVDLTNRFFCNCEPEY----------- 958
CIC PGF C I+I+ECS EP C GTC + F C C P +
Sbjct: 1954 CICPPGFQVQSDHC-IDIDECSEEPNLCLF-GTCTNSPGSFQCLCPPGFVLSDNGHRCFD 2011
Query: 959 -HGPFC--ELDVNKCKISPCLDEEN---CVYRTDG-----------------YNCLCAPG 995
FC + KC + + C + G + LC G
Sbjct: 2012 TRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFG 2071
Query: 996 YTGI----NCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSG----FFGTHCETNANDC 1046
+ + + +++EC P + +GVC++ + C+C G F G +C
Sbjct: 2072 HGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECS 2131
Query: 1047 LSNPCLHGRCTELINEYPCSCDADGTSTQCKI---KINDCTSIPCMNEGFCQKSAHGFTC 1103
+ +PC G CT +I + C+C ADG + I++C+ P + C + + C
Sbjct: 2132 VGHPCGQGTCTNVIGGFECAC-ADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLC 2190
Query: 1104 ICPRGYT----GAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF-----S 1154
CP GYT GA C + +D CA+ + + C G+ TF C C PG S
Sbjct: 2191 TCPAGYTLREDGAMC-RDVDECADGQQD---CHARGMECKNLIGTFACVCPPGMRPLPGS 2246
Query: 1155 GQFCEININECSSSP--CLHGADCEDHINGYVCKCQPGW 1191
G+ C + NEC + P C++G C + + C C G+
Sbjct: 2247 GEGC-TDDNECHAQPDLCVNGR-CVNTAGSFRCDCDEGF 2283
Score = 232 bits (592), Expect = 4e-60
Identities = 301/1253 (24%), Positives = 457/1253 (36%), Gaps = 281/1253 (22%)
Query: 159 CPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF----SGKYCQEL 214
C G L+ K ++ +G CL+E S +SC C+P F G YC ++
Sbjct: 516 CNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS--FSCLCKPGFLLAPGGHYCMDI 573
Query: 215 DACSFKPCKNNGSCINKRENWDEQAYECVCHPPFT----GKNC------SEIIGQCQPHV 264
D C NG C N E ++ C C G+ C S G +
Sbjct: 574 DECQTPGICVNGHCTN-----TEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGS 628
Query: 265 CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSA-YTYECPKG 323
C +T + C + G C+ +CP SA + C G
Sbjct: 629 CARPFPGTVTKSECCCANPDHGFGEPCQ---------------LCPAKDSAEFQALCSSG 673
Query: 324 SSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIF----TDLLCKSIQTSCESF 377
D++E +L P C NG C + C+C+ + + C + +
Sbjct: 674 LGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 378 PLRNNATCKKCEKDYPCSCISGF---TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKY 434
L +N C+ Y CSC GF + K +D C LS C++ C N+ G +
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC--LSSPCVSGV-CRNLAGSYTC 789
Query: 435 VCIPG------------CTKNPCWF----------LKNVYLIHQHLCYCGVTFHGICQDK 472
C PG TK CW L+ L + G + C+
Sbjct: 790 KCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCE-- 847
Query: 473 GPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK 532
+ + GFA G C V + F + VN C EG
Sbjct: 848 -RCEIDPACARGFARMTGVTCDDVNECESF--PGVCPNGRCVNTAGSFRCEC---PEGLM 901
Query: 533 EICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSC 592
+ A+G C+ CFLRW E+EC + C C
Sbjct: 902 -LDASGRLCVDVRLEP-----CFLRW------------DEDEC--GVTLPGKYRMDVCCC 941
Query: 593 SLSYI---------------------------------GRLCVVNVDYCLGNHSISVHGL 619
S+ + GR +V+ C + HG
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 620 C--LALSHNCNCSG---LQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFK 674
C S +C C+G L ERN +ID C G T + G F +C PG++
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG-TCVNTPGSFECECFPGYE 1060
Query: 675 G-----TQCEIDIDECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVG 727
C +D+DECA P C+ G TC + G+Y CQC P ++ G
Sbjct: 1061 SGFMLMKNC-MDVDECARDPLLCR-GGTCTNTDGSYKCQCPPGHELT----------AKG 1108
Query: 728 IRCEQDIDDCILN--ACEHNSTCKDLHLSYQCVCLSDWEGNFCEQ---ESNECKMNPCKN 782
CE DID+C L+ C H C ++ ++QC C + ++ Q + NEC++
Sbjct: 1109 TACE-DIDECSLSDGLCPHGQ-CVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC 1166
Query: 783 NSTCTDLYKSYRCECTSGWT----GQNCSEEINECDSDP--CMNGGLCHESTIPGQFVCL 836
+ C + SYRC C G++ G+ C+ +++EC+ +P C G H + +PG CL
Sbjct: 1167 DVHCINTEGSYRCSCGQGYSLMPDGRACA-DVDECEENPRVCDQG---HCTNMPGGHRCL 1222
Query: 837 CPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLF 896
C Y G C VD ++ C+++ CL
Sbjct: 1223 C---YDGFMATPDMRTC----------------VDVDE------------CDLNPHICL- 1250
Query: 897 LSCQDYGDCEDMVNNFRCICRPGF---SGSLCEIEINEC--SSEPCKNNGTCVDLTNRFF 951
+GDCE+ +F C C+ G+ G+ +++EC C ++ +C+++ F
Sbjct: 1251 -----HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFS 1305
Query: 952 CNCEPEYHGPFCEL-DVNKC--KISPCLDEENCVYRTDGYNCLCAPGYT--GINCEINLD 1006
C C P + G E D+++C + C +C+ Y C C G+ G CE + D
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCE-DRD 1364
Query: 1007 ECLSEPCLHD-GVCIDGINHYTCDCKSGFFGTH----CETNANDCLSNPCLHGRCTELIN 1061
EC L D G C++ Y C+C+ GF T C+ N C G C L
Sbjct: 1365 ECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG 1424
Query: 1062 EYPCSC----DADGTSTQCKIKINDCTS-IPCMNEGFCQKSAHGFTCICPRGY----TGA 1112
+ C C + D C IN+C + C+N G C + + C CP+ + +G
Sbjct: 1425 MFRCICNGGYELDRGGGNC-TDINECADPVNCIN-GVCINTPGSYLCSCPQDFELNPSGV 1482
Query: 1113 YC-EKSIDNC---AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEI-------- 1160
C + NC +S I + I V G C L G CE+
Sbjct: 1483 GCVDTRAGNCFLETHDRGDSGISCSAEIGV-GVTRASCCCSLGRAWGNPCELCPMANTTE 1541
Query: 1161 ---------------------NINECSSSPCL-HGADCEDHINGYVCKCQPGW--SGHH- 1195
+I+EC P L G DC + + C+C PG+ S H
Sbjct: 1542 YRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTR 1601
Query: 1196 -CENELECIPNS--CVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
CE+ EC +S C C TC+C ++ + G C D +R+ C
Sbjct: 1602 ICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMD-MRKSVC 1653
Score = 231 bits (588), Expect = 1e-59
Identities = 307/1180 (26%), Positives = 446/1180 (37%), Gaps = 214/1180 (18%)
Query: 180 SEFCSGHGKCLSEAW--------SKTYSCHCQPPF----SGKYCQELD--ACSFK----P 221
+E C +CLS + +Y+C C P SG +C + C K
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESR 820
Query: 222 CKNN--------GSCINKRENWDEQAYECVCHPP-------FTGKNCSEIIGQCQ--PHV 264
C+ N C W C P TG C ++ +C+ P V
Sbjct: 821 CEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDV-NECESFPGV 879
Query: 265 CFHGNCSNITSNSFICECDEQF----SGPFC-EVSAKPCVSLLFWKRGIC----PNSSSA 315
C +G C N T+ SF CEC E SG C +V +PC L W C P
Sbjct: 880 CPNGRCVN-TAGSFRCECPEGLMLDASGRLCVDVRLEPC--FLRWDEDECGVTLPGKYRM 936
Query: 316 YTYECPKGS-----SSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSI 370
C G+ + + EF+ + C G S D + P + D+
Sbjct: 937 DVCCCSIGAVWGVECEACPDPESLEFASL-CPRGLGFA--SRDFLS-GRPFYKDV----- 987
Query: 371 QTSCESFP-LRNNATCKKCEKDYPCSCISGFT----EKNCEKAIDHCKLLSINCLNEEWC 425
C+ FP L + TC+ + C+C GF E+NC ID C++ C + C
Sbjct: 988 -NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-IDECRISPDLC-GQGTC 1044
Query: 426 FNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGF 485
N G F+ C PG ++ +KN + + + G C + +
Sbjct: 1045 VNTPGSFECECFPGY-ESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSY--------- 1094
Query: 486 AGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPH-EGTKEICANGCSCLSE 544
KCQ ED +++ ++ C PH + I A CSC +
Sbjct: 1095 ------KCQCPPGHELTAKGTACED---IDECSLSDGLC--PHGQCVNVIGAFQCSCHAG 1143
Query: 545 EDSQEYRYLCFLRWAGNMYLENTTDDQENECQHE-----AVCKDEINRPRCSCSLSYI-- 597
S R C NEC+ + C + RCSC Y
Sbjct: 1144 FQSTPDRQGCV---------------DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLM 1188
Query: 598 --GRLCVVNVDYCLGNHSISVHGLCLAL--SHNCNC-SGLQRYE--RNICEIDTEDCKSA 650
GR C +VD C N + G C + H C C G R ++D D
Sbjct: 1189 PDGRACA-DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Query: 651 SCKNGTTSTHLRGYFFRKCVPGF---KGTQCEIDIDEC--ASHPCKNGATCIDQPGNYFC 705
C +G + +G F C G+ KG D+DEC H C + A+C++ PG++ C
Sbjct: 1248 ICLHGDCE-NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC 1306
Query: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL--NACEHNSTCKDLHLSYQCVCLSDW 763
+C+P + V DGF C D+D+C+ + C C ++ SY+C C +
Sbjct: 1307 RCLPGW-VGDGFEC------------HDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF 1353
Query: 764 EGN--FCEQESNECKMN-PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINEC-DSDPCM 819
G+ FCE + +EC N +N C + YRCEC G+ + +E+ C D D C
Sbjct: 1354 AGDGFFCE-DRDECAENVDLCDNGQCLNAPGGYRCECEMGF---DPTEDHRACQDVDECA 1409
Query: 820 NGGLCHEST---IPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH- 875
G LC + +PG F C+C Y + N D+ N C + C+ V N
Sbjct: 1410 QGNLCAFGSCENLPGMFRCICNGGY--ELDRGGGNCTDI--NECADPVNCINGVCINTPG 1465
Query: 876 ---CICREEFE----GKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICR--PGFSGSLCE 926
C C ++FE G C FL D GD + C G + + C
Sbjct: 1466 SYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGD-----SGISCSAEIGVGVTRASCC 1520
Query: 927 IEINECSSEPCKNNGTCVDLTNRFFC----NCEPEYHGPFCELDVNKCKISPCLDEE-NC 981
+ PC+ R C +P E D+++C+ P L + +C
Sbjct: 1521 CSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILE-DIDECQELPGLCQGGDC 1579
Query: 982 VYRTDGYNCLCAPGY-----TGINCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSGFF 1035
V + C C PGY T I CE ++DEC + + G C + + +YTC C + +
Sbjct: 1580 VNTFGSFQCECPPGYHLSEHTRI-CE-DIDECSTHSGICGPGTCYNTLGNYTCVCPAEYL 1637
Query: 1036 GTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQ 1095
+ N D + C NE + + C I + PC E
Sbjct: 1638 QVNGGNNCMDMRKSVCFRHYNGTCQNEL--AFNVTRKMCCCSYNIGQAWNRPC--EACPT 1693
Query: 1096 KSAHGFTCIC----PRGYTGAYCEK--SIDNCAEPELNSVICLNGGICVDGPGHTFDCRC 1149
+ + +C P T + K ID C E IC NG IC++ G +F C C
Sbjct: 1694 PISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIP---AICANG-ICINQIG-SFRCEC 1748
Query: 1150 LPGFSGQF----CEININECSS--SPCLHGADCEDHINGYVCKCQPGWS---GHHCENEL 1200
GF+ CE +++EC S SPC ADC + Y CKC G+ G C
Sbjct: 1749 PAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRN 1807
Query: 1201 EC--IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
EC IPN C H CM+ E CLC GF + LC D
Sbjct: 1808 ECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 223 bits (569), Expect = 2e-57
Identities = 284/1112 (25%), Positives = 424/1112 (38%), Gaps = 203/1112 (18%)
Query: 239 AYECVCHPPFT----GKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
++ C C F +NC++I +C+ P +C G C N T SF CEC + F
Sbjct: 1008 SFHCACAGGFALDAQERNCTDI-DECRISPDLCGQGTCVN-TPGSFECECFPGYESGF-- 1063
Query: 293 VSAKPCVSL-------LFWKRGICPNSSSAYTYECPKGSSSQNGET---DVSEFSLVP-- 340
+ K C+ + L + G C N+ +Y +CP G T D+ E SL
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 341 CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNAT---CKKCEKDYPCSCI 397
C +G C+ + C C F + ++N C E Y CSC
Sbjct: 1124 CPHG-QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG 1182
Query: 398 SGFTEKNCEKA---IDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNP----CWFLKN 450
G++ +A +D C+ C ++ C N+ G + +C G P C +
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVC-DQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDE 1241
Query: 451 VYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTED 510
L + H+C HG C++ F QLG+ +G A C++
Sbjct: 1242 CDL-NPHIC-----LHGDCENT-KGSFVCHCQLGYMVRKG-------------ATGCSD- 1280
Query: 511 ATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDD 570
V++ E +C + SCL+ S R C W G+ + + D+
Sbjct: 1281 ---VDECEVGGHNC-----------DSHASCLNIPGSFSCR--CLPGWVGDGFECHDLDE 1324
Query: 571 ---QENECQHEAVCKDEINRPRCSCSLSYIGR--------LCVVNVDYCLGNHSISVHGL 619
QE+ C C + RC+C + G C NVD C ++ G
Sbjct: 1325 CVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPG- 1383
Query: 620 CLALSHNCNCS-GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFK---- 674
+ C C G E + D ++C + + +L G F C G++
Sbjct: 1384 ----GYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRG 1439
Query: 675 GTQCEIDIDECASHP-CKNGATCIDQPGNYFCQCVPPFKV-VDGFSCL------C----- 721
G C DI+ECA C NG CI+ PG+Y C C F++ G C+ C
Sbjct: 1440 GGNCT-DINECADPVNCINGV-CINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETH 1497
Query: 722 NPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCK 781
+ G GI C +I + A S C L ++ N C++ P
Sbjct: 1498 DRGDSGISCSAEIGVGVTRA----SCCCSLGRAW----------------GNPCELCPMA 1537
Query: 782 NNSTCTDLYKSYRCECTSGWTGQN-----CSEEINECDSDPCM-NGGLCHESTIPGQFVC 835
N + YR C G Q E+I+EC P + GG C + G F C
Sbjct: 1538 NTT-------EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTF--GSFQC 1588
Query: 836 LCPPLYTGQFCHQRYNLCDLL-----HNPCRNNSTCLALVDANQHCICREEF----EGKN 886
CPP G + +C+ + H+ TC + N C+C E+ G N
Sbjct: 1589 ECPP---GYHLSEHTRICEDIDECSTHSGICGPGTCYNTL-GNYTCVCPAEYLQVNGGNN 1644
Query: 887 CEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDL 946
C K F E N R +C C I + + PC+ T +
Sbjct: 1645 CMDMRKSVCFRHYNGTCQNELAFNVTRKMC-------CCSYNIGQAWNRPCEACPTPISP 1697
Query: 947 TNRFFC-NCEPEYHGPFCE---LDVNKCKISPCLDEEN-CVYRTDGYNCLCAPGYTG--- 998
+ C N P + LD+++C P + C+ + + C C G+
Sbjct: 1698 DYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSI 1757
Query: 999 -INCEINLDECLSE--PCLHDGVCIDGINHYTCDCKSGFF---GTHCETNANDC--LSNP 1050
+ CE ++DEC S PC + CI+ Y C C G+ G C N+C + N
Sbjct: 1758 LLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGAC-VGRNECREIPNV 1815
Query: 1051 CLHGRCTELINEYPCSC----DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICP 1106
C HG C + Y C C A T C + I++C PC N G C+ + C+C
Sbjct: 1816 CSHGDCMDTEGSYMCLCHRGFQASADQTLC-MDIDECDRQPCGN-GTCKNIIGSYNCLCF 1873
Query: 1107 RGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFS----GQFCEINI 1162
G+ + +D L +C G C++ G +F C C GF G+ C ++
Sbjct: 1874 PGFVVTHNGDCVDFDECTTLVGQVC-RFGHCLNTAG-SFHCLCQDGFELTADGKNC-VDT 1930
Query: 1163 NECSS--SPCLHGADCEDHINGYVCKCQPGWS--GHHCENELECI--PNSCVHELCMENE 1216
NEC S CL G C++ + C C PG+ HC + EC PN C+ C N
Sbjct: 1931 NECLSLAGTCLPGT-CQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCT-NS 1988
Query: 1217 PGS-TCLCTPGFMTCSIGLLCGDEIRRITCLT 1247
PGS CLC PGF+ G C D R+ C T
Sbjct: 1989 PGSFQCLCPPGFVLSDNGHRCFD-TRQSFCFT 2019
Score = 218 bits (556), Expect = 6e-56
Identities = 306/1228 (24%), Positives = 472/1228 (38%), Gaps = 221/1228 (17%)
Query: 178 LSSEFCSGHGKCLSEAWSKTYSCHCQPPFSG-----KYCQELDACSFKP--CKNNGSCIN 230
+S + C G G C++ S + C C P + K C ++D C+ P C+ G+C N
Sbjct: 1034 ISPDLC-GQGTCVNTPGS--FECECFPGYESGFMLMKNCMDVDECARDPLLCRG-GTCTN 1089
Query: 231 KRENWDEQAYECVCHP--PFTGKNCS-EIIGQCQ--PHVCFHGNCSNITSNSFICECDEQ 285
+ +Y+C C P T K + E I +C +C HG C N+ +F C C
Sbjct: 1090 T-----DGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIG-AFQCSCHAG 1143
Query: 286 FSGPFCEVSAKPCVSLLFWKRGI---CPNSSSAYTYECPKGSSSQ---NGETDVSEFSLV 339
F G C N+ +Y C +G S DV E
Sbjct: 1144 FQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEEN 1203
Query: 340 P--CQNGTDCIKISNDVMCICSPIFT---DLLCKSIQTSCESFP-LRNNATCKKCEKDYP 393
P C G C + C+C F D+ C+ P + + C+ + +
Sbjct: 1204 PRVCDQG-HCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFV 1262
Query: 394 CSCISGFTEKNCEKA---IDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKN--PCWFL 448
C C G+ + +D C++ NC + C NI G F C+PG + C L
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDL 1322
Query: 449 KN--------------VYLIHQHLCYCGVTFHG---ICQDK-----------------GP 474
+ + + C C F G C+D+ P
Sbjct: 1323 DECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAP 1382
Query: 475 AQFEYVWQLGFAGSEGEK-CQGVID-AYFFLAA-----------NCTEDATYVNDPEDNN 521
+ ++GF +E + CQ V + A L A C + Y D N
Sbjct: 1383 GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGN 1442
Query: 522 ----SSCWFPHEGTKEICANG-----CSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQE 572
+ C P +C N CSC + + C AGN +LE T D +
Sbjct: 1443 CTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLE-THDRGD 1501
Query: 573 NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGL 632
+ A + R C CSL GR + C ++ LC G
Sbjct: 1502 SGISCSAEIGVGVTRASCCCSL---GRAWGNPCELCPMANTTEYRTLC------PGGEGF 1552
Query: 633 QRYERNICEIDTEDCKS--ASCKNGTTSTHLRGYFFRKCVPGFKGTQ----CEIDIDECA 686
Q + D ++C+ C+ G + G F +C PG+ ++ CE DIDEC+
Sbjct: 1553 QPNRITVILEDIDECQELPGLCQGG-DCVNTFGSFQCECPPGYHLSEHTRICE-DIDECS 1610
Query: 687 SHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFS-------CLCNPGYVG---------- 727
+H C G TC + GNY C C + V+G + +C Y G
Sbjct: 1611 THSGICGPG-TCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNV 1669
Query: 728 ----IRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCE------QESNECKM 777
C +I CE T + YQ +C + G + + +EC
Sbjct: 1670 TRKMCCCSYNIGQAWNRPCEACPT--PISPDYQILCGNQAPGFLTDIHTGKPLDIDECGE 1727
Query: 778 NPC-KNNSTCTDLYKSYRCECTSGWTGQN---CSEEINECDS--DPCMNGGLCHESTIPG 831
P N C + S+RCEC +G+ + E+++EC S PC C IPG
Sbjct: 1728 IPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADC--INIPG 1785
Query: 832 QFVCLCP---PLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE 888
+ C C L G C R N C + N C ++ C+ + + C+C F+ +
Sbjct: 1786 SYRCKCTRGYKLSPGGACVGR-NECREIPNVC-SHGDCMD-TEGSYMCLCHRGFQASADQ 1842
Query: 889 ---IDVKDCLFLSCQDYGDCEDMVNNFRCICRPGF----SGSLCEIEINECSS---EPCK 938
+D+ +C C + G C++++ ++ C+C PGF +G ++ +EC++ + C+
Sbjct: 1843 TLCMDIDECDRQPCGN-GTCKNIIGSYNCLCFPGFVVTHNGDC--VDFDECTTLVGQVCR 1899
Query: 939 NNGTCVDLTNRFFCNCEPEYH----GPFCELDVNKC--KISPCLDEENCVYRTDGYNCLC 992
G C++ F C C+ + G C +D N+C CL C + C+C
Sbjct: 1900 -FGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTCL-PGTCQNLEGSFRCIC 1956
Query: 993 APGY--TGINCEINLDECLSEP--CLHDGVCIDGINHYTCDCKSGFF----GTHC-ETNA 1043
PG+ +C I++DEC EP CL G C + + C C GF G C +T
Sbjct: 1957 PPGFQVQSDHC-IDIDECSEEPNLCLF-GTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQ 2014
Query: 1044 NDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTC 1103
+ C + G+C+ P + + T C + + PC E Q+ + F
Sbjct: 2015 SFCFTR-FEAGKCS-----VPKAFNTTKTRCCCSKRPGEGWGDPC--ELCPQEGSAAFQE 2066
Query: 1104 ICPRGYTGAY-----CEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFC 1158
+CP G+ GA + ++ CAE N +C N G+CV+ G +F C C G+S F
Sbjct: 2067 LCPFGH-GAVPGPDDSREDVNECAE---NPGVCTN-GVCVNTDG-SFRCECPFGYSLDFT 2120
Query: 1159 EIN---INECS-SSPCLHGADCEDHINGYVCKCQPGWSG---HHCENELECIPNSCVHEL 1211
IN +ECS PC G C + I G+ C C G+ CE+ EC N +
Sbjct: 2121 GINCVDTDECSVGHPCGQGT-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAF 2179
Query: 1212 CMENEPGS-TCLCTPGFMTCSIGLLCGD 1238
N GS C C G+ G +C D
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 212 bits (540), Expect = 4e-54
Identities = 294/1119 (26%), Positives = 411/1119 (36%), Gaps = 245/1119 (21%)
Query: 255 EIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFS----GPFCEVSAKPCVSLLFWKRGI 308
E I +CQ P +C G+C N T SF CEC + CE + G
Sbjct: 1562 EDIDECQELPGLCQGGDCVN-TFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGT 1620
Query: 309 CPNSSSAYTYECPKGSSSQNGETDVSEFSLVPC---QNGTDCIKISNDV---MCICSPIF 362
C N+ YT CP NG + + C NGT +++ +V MC CS
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYN- 1679
Query: 363 TDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSC---ISGF-TEKNCEKA--IDHCKLLS 416
+ ++ CE+ P DY C GF T+ + K ID C +
Sbjct: 1680 ---IGQAWNRPCEACPT-------PISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIP 1729
Query: 417 INCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKG--- 473
C N C N IG F+ C G N ++ L + + CG + CQ
Sbjct: 1730 AICANGI-CINQIGSFRCECPAGFNYN------SILLACEDVDECG-SRESPCQQNADCI 1781
Query: 474 --PAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGT 531
P + G+ S G C G C E
Sbjct: 1782 NIPGSYRCKCTRGYKLSPGGACVG--------RNECRE---------------------I 1812
Query: 532 KEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHE----AVCKDEINR 587
+C++G C+ E S Y+C + T +EC + CK+ I
Sbjct: 1813 PNVCSHG-DCMDTEGS----YMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGS 1867
Query: 588 PRCSCSLSYI---GRLCVVNVDYC---LGNHSISVHGLCLALSHNCNCS-GLQRYERNIC 640
C C ++ CV + D C +G H L A S +C C G +
Sbjct: 1868 YNCLCFPGFVVTHNGDCV-DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKN 1926
Query: 641 EIDTEDCKS--ASCKNGTTSTHLRGYFFRKCVPGFK--GTQCEIDIDECASHP--CKNGA 694
+DT +C S +C GT +L G F C PGF+ C IDIDEC+ P C G
Sbjct: 1927 CVDTNECLSLAGTCLPGTCQ-NLEGSFRCICPPGFQVQSDHC-IDIDECSEEPNLCLFG- 1983
Query: 695 TCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV----GIRCEQDIDDCILNACEHN--STC 748
TC + PG+ F CLC PG+V G RC E S
Sbjct: 1984 TCTNSPGS--------------FQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 749 KDLHLSYQCVCLSDWEGN-------FCEQES-------------------------NECK 776
K + + C S G C QE NEC
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 777 MNP--CKNNSTCTDLYKSYRCECTSGW----TGQNCSEEINECDSDPCMNGGLCHEST-- 828
NP C N C + S+RCEC G+ TG NC D+D C G C + T
Sbjct: 2090 ENPGVC-TNGVCVNTDGSFRCECPFGYSLDFTGINC------VDTDECSVGHPCGQGTCT 2142
Query: 829 -IPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEF----E 883
+ G F C C + ++ + NP C + + C C + +
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHN-TEGSYLCTCPAGYTLRED 2201
Query: 884 GKNCEIDVKDCLF--LSCQDYG-DCEDMVNNFRCICRPGF-----SGSLCEIEINECSSE 935
G C DV +C C G +C++++ F C+C PG SG C + NEC ++
Sbjct: 2202 GAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDD-NECHAQ 2259
Query: 936 P--CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE------------ENC 981
P C N G CV+ F C+C+ + + + + PC E
Sbjct: 2260 PDLCVN-GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEA 2318
Query: 982 VYRTDGYNCLCAPGYT-GINCEINLDECLSEPCLHDGVC-IDGINHYTCDCKSGFFGTHC 1039
V R + C C G G CE+ C + G + Y C G T
Sbjct: 2319 VTRAE---CCCGGGRGWGPRCEL---------------CPLPGTSAYRKLCPHGSGYTAE 2360
Query: 1040 ETNANDC--LSNPCLHGRCTELINEYPCSCDA----DGTSTQCKIKINDCTSIPCMNEGF 1093
+ ++C L++ C HG C + + C C A D T+T C + +++C+ +P
Sbjct: 2361 GRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC-LDMDECSQVPKPCTFL 2419
Query: 1094 CQKSAHGFTCICPRGY----TGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRC 1149
C+ + F C CPRGY G C K +D C + N +CV+ G F CRC
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTC-KDLDECTSRQHNCQF-----LCVNTVG-AFTCRC 2472
Query: 1150 LPGFS--GQFCEININECSS--SPCLHGADCEDHINGYVCKCQPGW----SGHHCENELE 1201
PGF+ Q C N +ECS+ PC C + + C+C G+ SGH CE+ E
Sbjct: 2473 PPGFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 1202 CI-PNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDE 1239
C P+ C H C G C C GF S C DE
Sbjct: 2532 CDGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569
Score = 208 bits (529), Expect = 8e-53
Identities = 285/1170 (24%), Positives = 439/1170 (37%), Gaps = 230/1170 (19%)
Query: 228 CINKRENWDEQAYECVCHPPFTGKNCSEIIG--QCQPHVCFHGNCSNITSNSFICECDEQ 285
C+N R +Y C C+ +T E I +C C HG+C NI ++ C C
Sbjct: 419 CLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNI-PGTYHCRCYPG 477
Query: 286 FSG----PFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKG-SSSQNGETDVSE---FS 337
F C + VS G C N+ ++ C G S +G+ V +
Sbjct: 478 FQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECAT 537
Query: 338 LVPCQNGTDCIKISNDVMCICSPIFT----DLLCKSIQTSCESFPLRNNATCKKCEKDYP 393
C NG C+ C+C P F C I C++ + N C E +
Sbjct: 538 STMCVNGV-CLNEDGSFSCLCKPGFLLAPGGHYCMDID-ECQTPGICVNGHCTNTEGSFR 595
Query: 394 CSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYL 453
C C+ G +G VC+ ++ C+
Sbjct: 596 CQCLGGLA---------------------------VGTDGRVCVDTHVRSTCY-----GA 623
Query: 454 IHQHLC---YCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTED 510
I + C + G C P GF G + C A F A C+
Sbjct: 624 IEKGSCARPFPGTVTKSECCCANPDH-------GF-GEPCQLCPAKDSAEF--QALCSSG 673
Query: 511 ATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDD 570
D D N P E+CANG + E YR +C L + ++ TD
Sbjct: 674 LGITTDGRDINECALDP-----EVCANG---VCENLRGSYRCVCNLGYEAGASGKDCTD- 724
Query: 571 QENECQHEAV------CKDEINRPRCSCSLSY----IGRLCVVNVDYCLGNHSISVHGLC 620
+EC ++ C++ CSC + +C +VD CL + +S G+C
Sbjct: 725 -VDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC-KDVDECLSSPCVS--GVC 780
Query: 621 --LALSHNCNCSGLQRYERN--ICEIDTEDCKSASCKNGTTSTHLRGYFFRK-------- 668
LA S+ C C R + + C T+ + +L+G R
Sbjct: 781 RNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGA 840
Query: 669 --------------CVPGF---KGTQCEIDIDECASHP--CKNGATCIDQPGNYFCQCVP 709
C GF G C+ D++EC S P C NG C++ G++ C+C P
Sbjct: 841 AWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNG-RCVNTAGSFRCEC-P 897
Query: 710 PFKVVDGFSCLCNPGYVGIRCE--------------------QDIDDCILNA-----CEH 744
++D LC V +R E D+ C + A CE
Sbjct: 898 EGLMLDASGRLC----VDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEA 953
Query: 745 NSTCKDLHLSYQC------VCLSDWEGNFCEQESNECKMNP-CKNNSTCTDLYKSYRCEC 797
+ L + C G ++ NECK+ P + TC + S+ C C
Sbjct: 954 CPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCAC 1013
Query: 798 TSGWT----GQNCSEEINECDSDPCMNG-GLCHESTIPGQFVCLCPPLYTGQFCHQR--Y 850
G+ +NC+ +I+EC P + G G C + PG F C C P Y F +
Sbjct: 1014 AGGFALDAQERNCT-DIDECRISPDLCGQGTCVNT--PGSFECECFPGYESGFMLMKNCM 1070
Query: 851 NLCDLLHNP--CRNNSTCLALVDANQHCICREEFE----GKNCEIDVKDC-LFLSCQDYG 903
++ + +P CR TC D + C C E G CE D+ +C L +G
Sbjct: 1071 DVDECARDPLLCR-GGTC-TNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGLCPHG 1127
Query: 904 DCEDMVNNFRCICRPGFSGSLCE---IEINECSSEPCKNNGTCVDLTNRFFCNCEPEY-- 958
C +++ F+C C GF + ++INEC + + C++ + C+C Y
Sbjct: 1128 QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSL 1187
Query: 959 --HGPFCELDVNKCKISP-CLDEENCVYRTDGYNCLCAPGYTG---INCEINLDECLSEP 1012
G C DV++C+ +P D+ +C G+ CLC G+ + +++DEC P
Sbjct: 1188 MPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNP 1246
Query: 1013 --CLHDGVCIDGINHYTCDCKSGFF----------GTHCETNANDCLSNPCLHGRCTELI 1060
CLH G C + + C C+ G+ CE ++C S H C +
Sbjct: 1247 HICLH-GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDS----HASCLNIP 1301
Query: 1061 NEYPCSCDAD--GTSTQCKIKINDCTSIP--CMNEGFCQKSAHGFTCICPRGYT--GAYC 1114
+ C C G +C +++C S C G C + C C +G+ G +C
Sbjct: 1302 GSFSCRCLPGWVGDGFECH-DLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFC 1360
Query: 1115 EKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF----SGQFCEININECSSSPC 1170
E D CAE N +C NG C++ PG + C C GF + C+ +++EC+
Sbjct: 1361 EDR-DECAE---NVDLCDNGQ-CLNAPG-GYRCECEMGFDPTEDHRACQ-DVDECAQGNL 1413
Query: 1171 LHGADCEDHINGYVCKCQPGW----SGHHCENELECI-PNSCVHELCMENEPGS-TCLCT 1224
CE+ + C C G+ G +C + EC P +C++ +C+ N PGS C C
Sbjct: 1414 CAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-NTPGSYLCSCP 1472
Query: 1225 PGFMTCSIGLLCGDEIRRITCLTPIFQRTD 1254
F G+ C D R C R D
Sbjct: 1473 QDFELNPSGVGCVD-TRAGNCFLETHDRGD 1501
Score = 191 bits (484), Expect = 1e-47
Identities = 263/1016 (25%), Positives = 378/1016 (37%), Gaps = 203/1016 (19%)
Query: 247 PFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPF----------CEVSAK 296
P C EI P +C +G C N SF CEC F+ C
Sbjct: 1719 PLDIDECGEI-----PAICANGICIN-QIGSFRCECPAGFNYNSILLACEDVDECGSRES 1772
Query: 297 PCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDV--SEFSLVP--CQNGTDCIKISN 352
PC + C N +Y +C +G G V +E +P C +G DC+
Sbjct: 1773 PCQ-----QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHG-DCMDTEG 1826
Query: 353 DVMCICSPIFT----DLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA 408
MC+C F LC I C+ P N TCK Y C C GF +
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDID-ECDRQPC-GNGTCKNIIGSYNCLCFPGFVVTHNGDC 1884
Query: 409 ID--HCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFH 466
+D C L C N G F +C G KN ++ L G
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADG--KNCVDTNECLSLAGTCLP 1942
Query: 467 GICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTED------ATYVNDPEDN 520
G CQ+ F + GF + + C + + C+E+ T N P
Sbjct: 1943 GTCQNL-EGSFRCICPPGFQ-VQSDHCIDIDE--------CSEEPNLCLFGTCTNSP--G 1990
Query: 521 NSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRW-AGNMYLE---NTTDDQENECQ 576
+ C P + NG C S CF R+ AG + NTT
Sbjct: 1991 SFQCLCPPGFV--LSDNGHRCFDTRQS-----FCFTRFEAGKCSVPKAFNTT-------- 2035
Query: 577 HEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYE 636
+ RC CS G + C S + LC R +
Sbjct: 2036 ----------KTRCCCS-KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRED 2084
Query: 637 RNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPG----FKGTQCEIDIDECA-SHPCK 691
N C + C + C N G F +C G F G C +D DEC+ HPC
Sbjct: 2085 VNECAENPGVCTNGVCVNTD------GSFRCECPFGYSLDFTGINC-VDTDECSVGHPCG 2137
Query: 692 NGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDL 751
G TC + G + C C DGF PG + + CE DID+C LN C +
Sbjct: 2138 QG-TCTNVIGGFECACA------DGFE----PGLM-MTCE-DIDECSLNPLLCAFRCHNT 2184
Query: 752 HLSYQCVCLSDW----EGNFCEQESNECK--MNPCK-NNSTCTDLYKSYRCECTSGW--- 801
SY C C + + +G C ++ +EC C C +L ++ C C G
Sbjct: 2185 EGSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 802 --TGQNCSEEINECDSDP--CMNGGLCHESTIPGQFVCLCP----PLYTGQFCHQ-RYNL 852
+G+ C+++ NEC + P C+NG + + G F C C P T CH R
Sbjct: 2244 PGSGEGCTDD-NECHAQPDLCVNGRCVNTA---GSFRCDCDEGFQPSPTLTECHDIRQGP 2299
Query: 853 C--DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEI--------------------- 889
C ++L CR+ S+ V + C G CE+
Sbjct: 2300 CFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTA 2359
Query: 890 ---DVKDCLFLS--CQDYGDCEDMVNNFRCICRPGFS----GSLCEIEINECSSEPCKNN 940
DV +C L+ C +G+C + + +FRC C+ G++ + C ++++ECS P
Sbjct: 2360 EGRDVDECRMLAHLCA-HGECINSLGSFRCHCQAGYTPDATATTC-LDMDECSQVPKPCT 2417
Query: 941 GTCVDLTNRFFCNCEPEYHGPFCELDVNKCK-ISPCLDEEN-----CVYRTDGYNCLCAP 994
C + F C+C Y E D CK + C ++ CV + C C P
Sbjct: 2418 FLCKNTKGSFLCSCPRGY---LLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPP 2474
Query: 995 GYTGIN--CEINLDECLSEP--CLHDGVCIDGINHYTCDCKSGFF----GTHCETNANDC 1046
G+T + C N DEC ++P C G C + + C+C GF G CE + N+C
Sbjct: 2475 GFTQHHQACFDN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNEC 2532
Query: 1047 LS-NPCLHGRCTELINEYPCSCDADGTS----TQCKIKINDCT-SIPCMNEGFCQKSAHG 1100
+ C HG C + Y CSC T QC + N+C S P C+ + G
Sbjct: 2533 DGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGG 2590
Query: 1101 FTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGI---CVDGPGHTFDCRCLPGF 1153
F C+CP G+ ++++ C E++ G C + PG F C C G+
Sbjct: 2591 FRCVCPSGFD---FDQALGGC--QEVDECAGRRGPCSYSCANTPG-GFLCGCPQGY 2640
Score = 155 bits (393), Expect = 5e-37
Identities = 257/1159 (22%), Positives = 405/1159 (34%), Gaps = 246/1159 (21%)
Query: 239 AYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPC 298
AY C F G++ QC +C S +C C + P C VS
Sbjct: 66 AYCCPGWRTFPGRS------QCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSG 119
Query: 299 VSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCIC 358
S+ G C +S C KG + + + C NG CI + C C
Sbjct: 120 CSVSCMNGGTCRGASCL----CQKGYTGTVCGQPICDRG---CHNGGRCIGPNR---CAC 169
Query: 359 SPIFTDLLCKSIQTSCESFPLRNNATCKK------CEKDYPCSCIS---GFTEKNCEKAI 409
F C+ + F C+ C K C+ + G + C
Sbjct: 170 VYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQP 229
Query: 410 DHCKLLSINCLNEEWCFNIIGRFKYVCIPG-CTKNPCWFLKNVYLIHQHLCYCGVTFHGI 468
C+ I ++ C ++ + +PG C C V ++ C C V
Sbjct: 230 HPCRRGFIPNIHTGACQDVD---ECQAVPGLCQGGSC-----VNMVGSFHCRCPVGHR-- 279
Query: 469 CQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPH 528
D A +Y F+ G +C G + ++ C + CW
Sbjct: 280 LSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCD-----------RGRCWAAG 328
Query: 529 EGTKEICANGCSCLSEEDSQEYRYLCFLR----------WAGNM-YLENTTDDQENECQH 577
E+C S E++ LC R + G + + N +
Sbjct: 329 P-VPELCP-------PRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARL 380
Query: 578 EAVCKDEINRPRCSCSLSYIGRLCV-VNVDYCLGNHSISVHGLCLAL--SHNCNCS-GLQ 633
D P S IG + +D C ++ ++G CL S+ C C+ G
Sbjct: 381 NPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYT 440
Query: 634 RYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGT---QCEIDIDEC----- 685
+ R C ID ++C S+ C +G ++ G + +C PGF+ T Q +D+DEC
Sbjct: 441 QDVRGEC-IDVDECTSSPCHHGDC-VNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGG 498
Query: 686 --------------------------------------ASHPCKNGATCIDQPGNYFCQC 707
S C NG C+++ G++ C C
Sbjct: 499 LCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV-CLNEDGSFSCLC 557
Query: 708 VPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF 767
P F + G G C DID+C N C + S++C CL G
Sbjct: 558 KPGFLLAPG----------GHYC-MDIDECQTPGICVNGHCTNTEGSFRCQCLG---GLA 603
Query: 768 CEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWT---GQNCSEEINECDSDPCMNGGLC 824
+ C + STC + C T + C + +PC LC
Sbjct: 604 VGTDGRVCVDTHVR--STCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQ---LC 658
Query: 825 HESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFE- 883
+ +F LC + N C L C N C L + C+C +E
Sbjct: 659 -PAKDSAEFQALCSSGLGITTDGRDINECALDPEVCA-NGVCENL-RGSYRCVCNLGYEA 715
Query: 884 ---GKNCEIDVKDCLF--LSCQDYGDCEDMVNNFRCICRPGF----SGSLCEIEINECSS 934
GK+C DV +C L C D G C++ ++ C C PGF +C+ +++EC S
Sbjct: 716 GASGKDC-TDVDECALNSLLC-DNGWCQNSPGSYSCSCPPGFHFWQDTEICK-DVDECLS 772
Query: 935 EPCKNNGTCVDLTNRFFCNCEP----EYHGPFC----------ELDVNKCKI-------- 972
PC +G C +L + C C P + G FC ++ ++C++
Sbjct: 773 SPCV-SGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 973 SPCLDEENCVYRTDGYNC----LCAPGY---TGINCEINLDECLSEP-CLHDGVCIDGIN 1024
S C + + C CA G+ TG+ C+ +++EC S P +G C++
Sbjct: 832 SECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAG 890
Query: 1025 HYTCDCKSGFFGTHCETNANDCLSNPC------------LHGR------CTELINEYPCS 1066
+ C+C G D PC L G+ C + +
Sbjct: 891 SFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVE 950
Query: 1067 CDA----------------------DGTSTQCKIK-INDCTSIPCM-NEGFCQKSAHGFT 1102
C+A D S + K +N+C P + G C+ + F
Sbjct: 951 CEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFH 1010
Query: 1103 CICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQF----- 1157
C C G+ E++ + E ++ +C G CV+ PG +F+C C PG+ F
Sbjct: 1011 CACAGGFALDAQERNCTDIDECRISPDLC-GQGTCVNTPG-SFECECFPGYESGFMLMKN 1068
Query: 1158 CEININECSSSPCL-HGADCEDHINGYVCKCQPGW----SGHHCENELECIPNS--CVHE 1210
C ++++EC+ P L G C + Y C+C PG G CE+ EC + C H
Sbjct: 1069 C-MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHG 1127
Query: 1211 LCMENEPGSTCLCTPGFMT 1229
C+ C C GF +
Sbjct: 1128 QCVNVIGAFQCSCHAGFQS 1146
Score = 130 bits (327), Expect = 2e-29
Identities = 179/752 (23%), Positives = 276/752 (36%), Gaps = 169/752 (22%)
Query: 640 CEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699
C + S SC NG T RG C G+ GT C I C NG CI
Sbjct: 112 CGVSRGSGCSVSCMNGGTC---RGASCL-CQKGYTGTVCGQPI---CDRGCHNGGRCIGP 164
Query: 700 PGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDI--DDCI----LNACEHNSTCKDLHL 753
C C G++G +CE+D C C+H T
Sbjct: 165 N-----------------RCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTK 207
Query: 754 SYQCVCLSDWEGNFCE----------------------QESNECKMNP--CKNNSTCTDL 789
+ C + G CE Q+ +EC+ P C+ S C ++
Sbjct: 208 ALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNM 266
Query: 790 YKSYRCECTSGWTGQNCSEEINECDSDPCMN---GGLCHESTIPGQFV----------C- 835
S+ C C G + S + + C + GG C + G + C
Sbjct: 267 VGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRC-AGDLAGHYTRRQCCCDRGRCW 325
Query: 836 -------LCPPLYTGQF---CHQRYNLCD--------LLHNPCRNNSTCLALVDANQHCI 877
LCPP + +F C QR L LL L N H
Sbjct: 326 AAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGS 385
Query: 878 CREEFEGK------------NCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSL- 924
N ID+ C + G C +++RC C G++ +
Sbjct: 386 DARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLN-GRCLPTPSSYRCECNVGYTQDVR 444
Query: 925 --CEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE---LDVNKCKISPCLDE- 978
C I+++EC+S PC ++G CV++ + C C P + +DV++C +S L
Sbjct: 445 GEC-IDVDECTSSPC-HHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHL 502
Query: 979 ENCVYRTDGYNCLCAPGYT----GINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGF 1034
CV + C+C G+ G NC ++ +EC + +GVC++ ++C CK GF
Sbjct: 503 GRCVNTEGSFQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDGSFSCLCKPGF 561
Query: 1035 F---GTHCETNANDCLS-NPCLHGRCTELINEYPCSC------DADG---------TSTQ 1075
G H + ++C + C++G CT + C C DG ++
Sbjct: 562 LLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCY 621
Query: 1076 CKIKINDC----------TSIPCMN--EGF---CQ----KSAHGFTCICPRGYTGAYCEK 1116
I+ C + C N GF CQ K + F +C G +
Sbjct: 622 GAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGR 681
Query: 1117 SIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF----SGQFCEININECSSSPCL- 1171
I+ CA L+ +C NG +C + G ++ C C G+ SG+ C +++EC+ + L
Sbjct: 682 DINECA---LDPEVCANG-VCENLRG-SYRCVCNLGYEAGASGKDCT-DVDECALNSLLC 735
Query: 1172 HGADCEDHINGYVCKCQPG---WSGHH-CENELECIPNSCVHELCMENEPGSTCLCTPGF 1227
C++ Y C C PG W C++ EC+ + CV +C TC C PG
Sbjct: 736 DNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGS 795
Query: 1228 MTCSIGLLCGDEIRRITCLTPIFQRTDPISTQ 1259
G C D + TC I + ++ Q
Sbjct: 796 RLDPSGTFCLDSTKG-TCWLKIQESRCEVNLQ 826
Score = 83.2 bits (204), Expect = 4e-15
Identities = 118/472 (25%), Positives = 163/472 (34%), Gaps = 139/472 (29%)
Query: 197 TYSCHCQPPFS----GKYCQELDACSF--KPCKNNG-SCINKRENWDEQAYECVCHP--- 246
+Y C C ++ G C+++D C+ + C G C N + CVC P
Sbjct: 2187 SYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGT-----FACVCPPGMR 2241
Query: 247 --PFTGKNCSEIIGQC--QPHVCFHGNCSNITSNSFICECDEQFS-------------GP 289
P +G+ C++ +C QP +C +G C N T+ SF C+CDE F GP
Sbjct: 2242 PLPGSGEGCTDD-NECHAQPDLCVNGRCVN-TAGSFRCDCDEGFQPSPTLTECHDIRQGP 2299
Query: 290 -FCEVSAKPCVSLLFWKRGI-------------------CP-NSSSAYTYECPKGSSSQN 328
F EV C SL + CP +SAY CP GS
Sbjct: 2300 CFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTA 2359
Query: 329 GETDVSEFSLVP--CQNGTDCIKISNDVMCIC----SPIFTDLLCKSIQTSCESFPLRNN 382
DV E ++ C +G +CI C C +P T C + C P
Sbjct: 2360 EGRDVDECRMLAHLCAHG-ECINSLGSFRCHCQAGYTPDATATTCLDMD-ECSQVPKPCT 2417
Query: 383 ATCKKCEKDYPCSCISGFT----EKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438
CK + + CSC G+ + C K +D C NC + C N +G F C P
Sbjct: 2418 FLCKNTKGSFLCSCPRGYLLEEDGRTC-KDLDECTSRQHNC--QFLCVNTVGAFTCRCPP 2474
Query: 439 GCTKNPCWFLKNVYLIHQHLCY-----------CGVTFHGICQDKGPAQFEYVWQLGFA- 486
G T+ H C+ CG HG C + P F GF
Sbjct: 2475 GFTQ------------HHQACFDNDECSAQPGPCGA--HGHCHNT-PGSFRCECHQGFTL 2519
Query: 487 GSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEED 546
S G C+ V + C PH C +GC +
Sbjct: 2520 VSSGHGCEDV-------------------------NECDGPHR-----CQHGC----QNQ 2545
Query: 547 SQEYRYLCFLRWAGNMYLENTTDDQENECQ------HEAVCKDEINRPRCSC 592
YR C + + D ENEC A C++ + RC C
Sbjct: 2546 LGGYRCSCPQGFTQHSQWAQCVD--ENECALSPPTCGSASCRNTLGGFRCVC 2595
Score = 70.1 bits (170), Expect = 3e-11
Identities = 142/612 (23%), Positives = 209/612 (34%), Gaps = 162/612 (26%)
Query: 186 HGKCLSEAWSKTYSCHC----QPPFSGKYCQELDACSF-KPCKNNGSCINKRENWDEQAY 240
+G C++ S + C C F+G C + D CS PC G+C N +
Sbjct: 2097 NGVCVNTDGS--FRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNV-----IGGF 2148
Query: 241 ECVCHPPFTG--KNCSEIIGQC--QPHVCFHGNCSNITSNSFICECDEQFS----GPFC- 291
EC C F E I +C P +C C N T S++C C ++ G C
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLNPLLCAF-RCHN-TEGSYLCTCPAGYTLREDGAMCR 2206
Query: 292 EVSAKPCVSLLFWKRGI-CPNSSSAYTYECPKG----SSSQNGETDVSEFSLVP--CQNG 344
+V RG+ C N + CP G S G TD +E P C NG
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNG 2266
Query: 345 TDCIKISNDVMCIC------------------SPIFTDLL---CKSIQTS---------- 373
C+ + C C P F ++L C+S+ +S
Sbjct: 2267 R-CVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECC 2325
Query: 374 ----------CESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEE 423
CE PL + +K C SG+T + + +D C++L+ C + E
Sbjct: 2326 CGGGRGWGPRCELCPLPGTSAYRKL-----CPHGSGYTAEG--RDVDECRMLAHLCAHGE 2378
Query: 424 WCFNIIGRFKYVCIPGCTKN-----------------PCWFL-KNVYLIHQHLCYCGVTF 465
C N +G F+ C G T + PC FL KN LC C +
Sbjct: 2379 -CINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTK--GSFLCSCPRGY 2435
Query: 466 HGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDP--EDNNSS 523
+ ++ G L S CQ FL N T P ++ +
Sbjct: 2436 --LLEEDG----RTCKDLDECTSRQHNCQ-------FLCVNTVGAFTCRCPPGFTQHHQA 2482
Query: 524 CWFPHEGTKEICANGCSCLSEEDSQEYRYLCF----LRWAGNMYLENTTDDQENECQHEA 579
C+ E + + G +R C L +G+ + D + CQH
Sbjct: 2483 CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG- 2541
Query: 580 VCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNI 639
C++++ RCSC + HS Q + N
Sbjct: 2542 -CQNQLGGYRCSCPQGFT-------------QHS----------------QWAQCVDENE 2571
Query: 640 CEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQ----CEIDIDECASHPCKNGAT 695
C + C SASC+N G F C GF Q C+ ++DECA +
Sbjct: 2572 CALSPPTCGSASCRN------TLGGFRCVCPSGFDFDQALGGCQ-EVDECAGRRGPCSYS 2624
Query: 696 CIDQPGNYFCQC 707
C + PG + C C
Sbjct: 2625 CANTPGGFLCGC 2636
Score = 58.2 bits (139), Expect = 1e-07
Identities = 90/331 (27%), Positives = 114/331 (34%), Gaps = 86/331 (25%)
Query: 910 NNFRCICRPG---FSG-SLCEIEI--NECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 963
+ F C PG F G S C + I C C C C P C
Sbjct: 62 SRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPN---------LCTCADGTLAPSC 112
Query: 964 ELDVNK-CKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDG 1022
+ C +S C++ C G +CLC GYTG C C + G CI G
Sbjct: 113 GVSRGSGCSVS-CMNGGTC----RGASCLCQKGYTGTVCG---QPICDRGCHNGGRCI-G 163
Query: 1023 INHYTCDCKSGFFGTHCETNANDCLSNPCL----HGRCTELINEYPCSCDADGTSTQCKI 1078
N C C GF G CE D + PC C + C T C
Sbjct: 164 PNR--CACVYGFMGPQCE---RDYRTGPCFGQVGPEGCQHQLTGLVC------TKALCCA 212
Query: 1079 KINDCTSIPCMNEGFCQKSAHGFTCICPRGY-----TGAYCEKSIDNC-AEPELNSVICL 1132
+ +PC C H C RG+ TGA C+ +D C A P L
Sbjct: 213 TVGRAWGLPC---ELCPAQPHP----CRRGFIPNIHTGA-CQ-DVDECQAVPGL-----C 258
Query: 1133 NGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHING------YVCK 1186
GG CV+ G +F CRC G + S S A CED+ G + +
Sbjct: 259 QGGSCVNMVG-SFHCRCPVG----------HRLSDS----SAACEDYRAGACFSVLFGGR 303
Query: 1187 CQPGWSGHHCENELECIPNSC-----VHELC 1212
C +GH+ + C C V ELC
Sbjct: 304 CAGDLAGHYTRRQCCCDRGRCWAAGPVPELC 334
Score = 48.5 bits (114), Expect = 1e-04
Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 10/94 (10%)
Query: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLN--N 2919
GA G S+V +C+ G + C + C +FSCRCLP W G+ C+ C++ +
Sbjct: 1274 GATGCSDVDECE---VGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 2920 LCLHQSLCIPDQSFSYSCLCTLGWVGR--YCENK 2951
C + C+ + SY C C G+ G +CE++
Sbjct: 1331 RCSPRGDCL-NVPGSYRCTCRQGFAGDGFFCEDR 1363
Score = 45.4 bits (106), Expect = 9e-04
Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 41/181 (22%)
Query: 189 CLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPF 248
C++ + SC CQ ++G C + C + C N G CI C C F
Sbjct: 124 CMNGGTCRGASCLCQKGYTGTVCGQ-PICD-RGCHNGGRCIGPN--------RCACVYGF 173
Query: 249 TGKNCSE------IIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEV---SAKPCV 299
G C GQ P C H + + + C + G CE+ PC
Sbjct: 174 MGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPC- 232
Query: 300 SLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCI 357
+RG PN +T C DV E VP CQ G+ C+ + C
Sbjct: 233 -----RRGFIPN---IHTGAC----------QDVDECQAVPGLCQGGS-CVNMVGSFHCR 273
Query: 358 C 358
C
Sbjct: 274 C 274
Score = 42.4 bits (98), Expect = 0.007
Identities = 22/74 (29%), Positives = 31/74 (41%), Gaps = 6/74 (8%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGS-FCTETVSTCDPEHDPPHHCSRGATCISLPHGYTC 2677
C + +C+ S C C GW G F + C + H CS C+++P Y C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQE---HRCSPRGDCLNVPGSYRC 1347
Query: 2678 FCPLGTT--GIYCE 2689
C G G +CE
Sbjct: 1348 TCRQGFAGDGFFCE 1361
Score = 42.0 bits (97), Expect = 0.010
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 9/64 (14%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS 2403
C N GTC C C + Y+G +C C+ C NG C+ + C C YG
Sbjct: 124 CMNGGTC----RGASCLCQKGYTGTVCGQPICDRG-CHNGGRCIGPNR----CACVYGFM 174
Query: 2404 GPLC 2407
GP C
Sbjct: 175 GPQC 178
Score = 40.4 bits (93), Expect = 0.028
Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGW----KGSFCTETVSTCDPEHDPPHHCS 2663
+C A P CG G C + S C C G+ G C E V+ CD PH C
Sbjct: 2488 ECSAQPGP---CGAHGHCHNTPGSFRCECHQGFTLVSSGHGC-EDVNECDG----PHRCQ 2539
Query: 2664 RGATCISLPHGYTCFCPLGTT 2684
G C + GY C CP G T
Sbjct: 2540 HG--CQNQLGGYRCSCPQGFT 2558
Score = 38.9 bits (89), Expect = 0.081
Identities = 31/98 (31%), Positives = 40/98 (40%), Gaps = 12/98 (12%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-ETVSTCDPEHDPPHHCSR 2664
+ +C SP CG G TC+ + S C C G++ F + D P C R
Sbjct: 1029 IDECRISPDL---CGQG-TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLC-R 1083
Query: 2665 GATCISLPHGYTCFCPLG----TTGIYCE--QALSISD 2696
G TC + Y C CP G G CE S+SD
Sbjct: 1084 GGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSD 1121
Score = 38.9 bits (89), Expect = 0.081
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 12/79 (15%)
Query: 2613 PCSLMKCGN------GGTCIESGTSVYCNCTTGWKGS---FCTETVSTCDPEHDPPHHCS 2663
P + +CG G CI S C C G+ + E V C P C
Sbjct: 1719 PLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESP---CQ 1775
Query: 2664 RGATCISLPHGYTCFCPLG 2682
+ A CI++P Y C C G
Sbjct: 1776 QNADCINIPGSYRCKCTRG 1794
Score = 36.6 bits (83), Expect = 0.40
Identities = 20/73 (27%), Positives = 26/73 (35%), Gaps = 19/73 (26%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSF--------CTETVSTCDPEHDPPHHCSRGATCI 2669
+C G C+ S C C G+ G C E V CD C+
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD-----------NGQCL 1379
Query: 2670 SLPHGYTCFCPLG 2682
+ P GY C C +G
Sbjct: 1380 NAPGGYRCECEMG 1392
Score = 36.2 bits (82), Expect = 0.53
Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 2623 GTCIESGTSVYCNCTTGW---KGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFC 2679
G C + S C+C G+ KG+ V C+ H+C A+C+++P ++C C
Sbjct: 1252 GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG---HNCDSHASCLNIPGSFSCRC 1308
Query: 2680 PLGTTG 2685
G G
Sbjct: 1309 LPGWVG 1314
Score = 35.4 bits (80), Expect = 0.90
Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 21/104 (20%)
Query: 2888 GECTVNGTTFSCRC------LPDWAG----NTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
G C +F C C PD N C S C+N +CL ++ S+SC
Sbjct: 503 GRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCL-------NEDGSFSC 555
Query: 2938 LCTLGWV----GRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNL 2977
LC G++ G YC + T N + + ++R + L
Sbjct: 556 LCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCL 599
Score = 35.0 bits (79), Expect = 1.2
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 11/74 (14%)
Query: 2876 GTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSY 2935
G+ C + C NGG C SC C + G C Q + + C + CI
Sbjct: 117 GSGCSVS-CMNGGTCR----GASCLCQKGYTGTVCGQPIC--DRGCHNGGRCIGPNR--- 166
Query: 2936 SCLCTLGWVGRYCE 2949
C C G++G CE
Sbjct: 167 -CACVYGFMGPQCE 179
Score = 34.7 bits (78), Expect = 1.5
Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Query: 2592 GLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSF----CTE 2647
G G G ++ V +C +P C NG C+ + S C C G+ F C +
Sbjct: 2071 GHGAVPGPDDSREDVNECAENPGV---CTNG-VCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Query: 2648 TVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
T E H C +G TC ++ G+ C C G
Sbjct: 2127 T-----DECSVGHPCGQG-TCTNVIGGFECACADG 2155
Score = 34.3 bits (77), Expect = 2.0
Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLG 2682
G C+ + +S C C G+ E + + P HH C+++P Y C C G
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHH----GDCVNIPGTYHCRCYPG 477
Query: 2683 TTGIYCEQA 2691
QA
Sbjct: 478 FQATPTRQA 486
Score = 33.5 bits (75), Expect = 3.4
Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 14/102 (13%)
Query: 2872 GDC-DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV----SCL--NNLCLHQ 2924
G+C D C + C +G + GT + CRC P + Q+ C+ LC H
Sbjct: 445 GECIDVDECTSSPCHHGDCVNIPGT-YHCRCYPGFQATPTRQACVDVDECIVSGGLC-HL 502
Query: 2925 SLCIPDQSFSYSCLCTLGWV----GRYCENKTSFSTAKFMGN 2962
C+ + S+ C+C G+ G+ C + +T+ N
Sbjct: 503 GRCVNTEG-SFQCVCNAGFELSPDGKNCVDHNECATSTMCVN 543
Score = 33.5 bits (75), Expect = 3.4
Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 1/59 (1%)
Query: 2622 GGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCP 2680
GG C+ + S C C G+ S T D C G TC + YTC CP
Sbjct: 1576 GGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPG-TCYNTLGNYTCVCP 1633
Score = 32.3 bits (72), Expect = 7.6
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 12/66 (18%)
Query: 2621 NGGT---CIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
NGG CI + S C+C G+ G C + V C+ + P C +G C ++P
Sbjct: 1163 NGGCDVHCINTEGSYRCSCGQGYSLMPDGRACAD-VDECE---ENPRVCDQGH-CTNMPG 1217
Query: 2674 GYTCFC 2679
G+ C C
Sbjct: 1218 GHRCLC 1223
Score = 32.3 bits (72), Expect = 7.6
Identities = 28/114 (24%), Positives = 38/114 (33%), Gaps = 35/114 (30%)
Query: 2319 FFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYS------------ 2366
FF D +N++ C +NG C++ CEC +
Sbjct: 1358 FFCEDRDECAENVDLC-----------DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVD 1406
Query: 2367 ----GKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
G LC F SCEN P C+ G ++ R G CTD P
Sbjct: 1407 ECAQGNLCAFGSCENLP--GMFRCICNGGYEL------DRGGGNCTDINECADP 1452
Score = 32.3 bits (72), Expect = 7.6
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 14/74 (18%)
Query: 2623 GTCIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
G+C C C G++ G CT+ DP + C G CI+ P Y C
Sbjct: 1417 GSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-----CINGV-CINTPGSYLCS 1470
Query: 2679 CP----LGTTGIYC 2688
CP L +G+ C
Sbjct: 1471 CPQDFELNPSGVGC 1484
Score = 32.0 bits (71), Expect = 9.9
Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 2347 NGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIV----CLCPYG 2401
NG C++ + + CECP YS + + C G C + T+++ C C G
Sbjct: 2097 NGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADG 2155
Score = 32.0 bits (71), Expect = 9.9
Identities = 23/85 (27%), Positives = 30/85 (35%), Gaps = 6/85 (7%)
Query: 2598 GHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHD 2657
G+ GR V +C L G CI S S C+C G+ T D
Sbjct: 2356 GYTAEGRDVDECRM----LAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ 2411
Query: 2658 PPHHCSRGATCISLPHGYTCFCPLG 2682
P C+ C + + C CP G
Sbjct: 2412 VPKPCT--FLCKNTKGSFLCSCPRG 2434
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 235 bits (599), Expect = 6e-61
Identities = 102/233 (43%), Positives = 138/233 (59%), Gaps = 7/233 (3%)
Query: 968 NKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYT 1027
++C +PC + C GY CLC GYTG+ CE ++DEC PCL++GVC D + +
Sbjct: 1195 HECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 1028 CDCKSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSI 1086
C+C SG+ G CE N N+C S+PCL+ G C + + Y C+C C+ ++N+C S
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 1087 PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFD 1146
PC+N C+ GF C CP G+ G C K++D C S C NG C DG ++F
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECL-----SQPCKNGATCKDG-ANSFR 1368
Query: 1147 CRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENE 1199
C C GF+G CE+NINEC S+PC + A C D +N Y CKCQPG+SG CE E
Sbjct: 1369 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 217 bits (553), Expect = 1e-55
Identities = 143/468 (30%), Positives = 205/468 (43%), Gaps = 50/468 (10%)
Query: 639 ICEIDTEDCKSAS--CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATC 696
I + ++ + K AS C+ G+ LRG R CV GT ++ C S C+ G+
Sbjct: 973 IADSNSLETKKASPFCRPGSV---LRG---RMCVNCPLGTYYNLEHFTCES--CRIGSYQ 1024
Query: 697 IDQPGNYFCQCVPP--------FKVVDGFSCLCNPGYVGIRCEQDIDDC----------- 737
D+ G C+ P + + C G + + C
Sbjct: 1025 -DEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGS 1083
Query: 738 --ILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRC 795
L+ E+ ST K ++ + EG F C +PC + + K++
Sbjct: 1084 RSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPC--HPCPRDYYQPNAGKAFCL 1141
Query: 796 ECTS-GWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 854
C G T S I EC S ST + PP G +
Sbjct: 1142 ACPFYGTTPFAGSRSITECSS---------FSSTFSAAEESVVPPASLGHIKKRHEISSQ 1192
Query: 855 LLH----NPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVN 910
+ H NPC N+ TC L C+C + G CE D+ +C L C + G C+D+V
Sbjct: 1193 VFHECFFNPCHNSGTCQQL-GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVG 1251
Query: 911 NFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKC 970
F C C G++G CE INECSS PC N G CVD + C C + G CE +VN+C
Sbjct: 1252 EFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNEC 1311
Query: 971 KISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDC 1030
+ +PCL+ C + G+ C C PG+ G C N+DECLS+PC + C DG N + C C
Sbjct: 1312 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLC 1371
Query: 1031 KSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCK 1077
+GF G+HCE N N+C SNPC + C + +N Y C C + +C+
Sbjct: 1372 AAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 209 bits (533), Expect = 3e-53
Identities = 96/235 (40%), Positives = 126/235 (53%), Gaps = 5/235 (2%)
Query: 732 QDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYK 791
Q +C N C ++ TC+ L Y C+C + G CE + +EC PC NN C DL
Sbjct: 1192 QVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVG 1251
Query: 792 SYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYN 851
+ CEC SG+TGQ C E INEC S PC+N G+C + + C C + G C N
Sbjct: 1252 EFICECPSGYTGQRCEENINECSSSPCLNKGICVDGV--AGYRCTCVKGFVGLHCETEVN 1309
Query: 852 LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNN 911
C NPC NN+ C V C C F G C +V +CL C++ C+D N+
Sbjct: 1310 ECQ--SNPCLNNAVCEDQVGGFL-CKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANS 1366
Query: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELD 966
FRC+C GF+GS CE+ INEC S PC+N TCVD N + C C+P + G CE +
Sbjct: 1367 FRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 203 bits (516), Expect = 2e-51
Identities = 94/235 (40%), Positives = 126/235 (53%), Gaps = 5/235 (2%)
Query: 807 SEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTC 866
S+ +EC +PC N G C + + +VCLCP YTG C + C L PC NN C
Sbjct: 1191 SQVFHECFFNPCHNSGTCQQ--LGRGYVCLCPLGYTGLKCETDIDECSPL--PCLNNGVC 1246
Query: 867 LALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCE 926
LV C C + G+ CE ++ +C C + G C D V +RC C GF G CE
Sbjct: 1247 KDLV-GEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE 1305
Query: 927 IEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD 986
E+NEC S PC NN C D F C C P + G C +V++C PC + C +
Sbjct: 1306 TEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGAN 1365
Query: 987 GYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCET 1041
+ CLCA G+TG +CE+N++EC S PC + C+D +N Y+C C+ GF G CET
Sbjct: 1366 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCET 1420
Score = 169 bits (428), Expect = 4e-41
Identities = 83/238 (34%), Positives = 122/238 (51%), Gaps = 17/238 (7%)
Query: 573 NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGL 632
N C + C+ C C L Y G C ++D C ++ +G+C L C
Sbjct: 1200 NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLN-NGVCKDLVGEFICECP 1258
Query: 633 QRYERNICEIDTEDCKSASCKN-GTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCK 691
Y CE + +C S+ C N G + GY CV GF G CE +++EC S+PC
Sbjct: 1259 SGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCT-CVKGFVGLHCETEVNECQSNPCL 1317
Query: 692 NGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDL 751
N A C DQ G GF C C PG++G RC +++D+C+ C++ +TCKD
Sbjct: 1318 NNAVCEDQVG--------------GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG 1363
Query: 752 HLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEE 809
S++C+C + + G+ CE NEC+ NPC+N +TC D SY C+C G++G+ C E
Sbjct: 1364 ANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 164 bits (415), Expect = 1e-39
Identities = 82/219 (37%), Positives = 113/219 (51%), Gaps = 23/219 (10%)
Query: 1044 NDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFT 1102
++C NPC + G C +L Y C C T +C+ I++C+ +PC+N G C+ F
Sbjct: 1195 HECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 1103 CICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEINI 1162
C CP GYTG CE++I+ C+ S CLN GICVDG + C C+ GF G CE +
Sbjct: 1255 CECPSGYTGQRCEENINECS-----SSPCLNKGICVDGVAG-YRCTCVKGFVGLHCETEV 1308
Query: 1163 NECSSSPCLHGADCEDHINGYVCKCQPGWSGHHC-ENELECIPNSCVH-ELCMENEPGST 1220
NEC S+PCL+ A CED + G++CKC PG+ G C +N EC+ C + C +
Sbjct: 1309 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFR 1368
Query: 1221 CLCTPGFM--------------TCSIGLLCGDEIRRITC 1245
CLC GF C C DE+ +C
Sbjct: 1369 CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSC 1407
Score = 138 bits (348), Expect = 8e-32
Identities = 77/246 (31%), Positives = 113/246 (45%), Gaps = 17/246 (6%)
Query: 528 HEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINR 587
HE C N +C ++ + Y LC L + G + + C + VCKD +
Sbjct: 1195 HECFFNPCHNSGTC--QQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE 1252
Query: 588 PRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDC 647
C C Y G+ C N++ C + ++ G+C+ C+ ++ + CE + +C
Sbjct: 1253 FICECPSGYTGQRCEENINECSSSPCLN-KGICVDGVAGYRCTCVKGFVGLHCETEVNEC 1311
Query: 648 KSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQC 707
+S C N G F KC PGF GT+C ++DEC S PCKNGATC D
Sbjct: 1312 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG-------- 1363
Query: 708 VPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF 767
+ F CLC G+ G CE +I++C N C + +TC D SY C C + G
Sbjct: 1364 ------ANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKR 1417
Query: 768 CEQESN 773
CE E +
Sbjct: 1418 CETEQS 1423
Score = 134 bits (338), Expect = 1e-30
Identities = 73/234 (31%), Positives = 101/234 (43%), Gaps = 7/234 (2%)
Query: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271
Q C F PC N+G+C + Y C+C +TG C I +C P C +
Sbjct: 1192 QVFHECFFNPCHNSGTCQQLG-----RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVC 1246
Query: 272 NITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGET 331
FICEC ++G CE + C S +GIC + + Y C KG + ET
Sbjct: 1247 KDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET 1306
Query: 332 DVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKD 391
+V+E PC N C +C C P F C C S P +N ATCK
Sbjct: 1307 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANS 1366
Query: 392 YPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC 445
+ C C +GFT +CE I+ C+ S C N+ C + + + C PG + C
Sbjct: 1367 FRCLCAAGFTGSHCELNINECQ--SNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 119 bits (298), Expect = 5e-26
Identities = 67/225 (29%), Positives = 94/225 (41%), Gaps = 8/225 (3%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYE 241
C G C + + Y C C ++G C+ ++D CS PC NNG C + +
Sbjct: 1202 CHNSGTC--QQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE-----FI 1254
Query: 242 CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
C C +TG+ C E I +C C + + C C + F G CE C S
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 302 LFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI 361
+C + + +CP G +V E PC+NG C +N C+C+
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAG 1374
Query: 362 FTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
FT C+ C+S P RN ATC Y C C GF+ K CE
Sbjct: 1375 FTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 96.7 bits (239), Expect = 3e-19
Identities = 54/216 (25%), Positives = 93/216 (43%), Gaps = 11/216 (5%)
Query: 159 CPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDAC 217
CPLG +K + + S C +G C + C C ++G+ C+E ++ C
Sbjct: 1219 CPLGY---TGLKCETDIDECSPLPCLNNGVCKDLVGE--FICECPSGYTGQRCEENINEC 1273
Query: 218 SFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNS 277
S PC N G C++ Y C C F G +C + +CQ + C +
Sbjct: 1274 SSSPCLNKGICVD-----GVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGG 1328
Query: 278 FICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS 337
F+C+C F G C + C+S C + ++++ C G + + E +++E
Sbjct: 1329 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQ 1388
Query: 338 LVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTS 373
PC+N C+ N C C P F+ C++ Q++
Sbjct: 1389 SNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQST 1424
Score = 75.9 bits (185), Expect = 6e-13
Identities = 47/133 (35%), Positives = 61/133 (45%), Gaps = 22/133 (16%)
Query: 1067 CDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPEL 1126
C +GT T I C PC N G CQ+ C CP G+ G CE+ I C P
Sbjct: 3456 CLENGTWTSPPICRAVCR-FPCQNGGICQRPN---ACSCPEGWMGRLCEEPI--CILP-- 3507
Query: 1127 NSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCK 1186
CLNGG CV + C C PG++G C + + SPCL+G C + C
Sbjct: 3508 ----CLNGGRCVA----PYQCDCPPGWTGSRCHTAVCQ---SPCLNGGKC---VRPNRCH 3553
Query: 1187 CQPGWSGHHCENE 1199
C W+GH+C +
Sbjct: 3554 CLSSWTGHNCSRK 3566
Score = 67.4 bits (163), Expect = 2e-10
Identities = 36/112 (32%), Positives = 52/112 (46%), Gaps = 6/112 (5%)
Query: 198 YSCHCQPPFSGKYC-QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
+ C C P F G C + +D C +PCKN +C + ++ C+C FTG +C
Sbjct: 1329 FLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKD-----GANSFRCLCAAGFTGSHCELN 1383
Query: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGI 308
I +CQ + C + NS+ C+C FSG CE +L F GI
Sbjct: 1384 INECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGI 1435
Score = 62.4 bits (150), Expect = 7e-09
Identities = 35/109 (32%), Positives = 45/109 (41%), Gaps = 20/109 (18%)
Query: 779 PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCP 838
PC+N C + C C GW G+ C E I PC+NGG C + C CP
Sbjct: 3475 PCQNGGICQ---RPNACSCPEGWMGRLCEEPICIL---PCLNGGRC-----VAPYQCDCP 3523
Query: 839 PLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
P +TG CH + +PC N C+ C C + G NC
Sbjct: 3524 PGWTGSRCHTA-----VCQSPCLNGGKCV----RPNRCHCLSSWTGHNC 3563
Score = 61.6 bits (148), Expect = 1e-08
Identities = 50/164 (30%), Positives = 67/164 (40%), Gaps = 33/164 (20%)
Query: 646 DCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFC 705
D + SC +G L G+ C+ T I C PC+NG C +P
Sbjct: 3436 DMITYSCYSGYM---LEGFLRSVCLENGTWTSPPICRAVCR-FPCQNGGIC-QRPN---- 3486
Query: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEG 765
+C C G++G CE+ I CIL C + C YQC C W G
Sbjct: 3487 ------------ACSCPEGWMGRLCEEPI--CIL-PCLNGGRCV---APYQCDCPPGWTG 3528
Query: 766 NFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEE 809
+ C + C+ +PC N C + RC C S WTG NCS +
Sbjct: 3529 SRCH--TAVCQ-SPCLNGGKCV---RPNRCHCLSSWTGHNCSRK 3566
Score = 57.4 bits (137), Expect = 2e-07
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 10/87 (11%)
Query: 2603 GRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHC 2662
G++V +C + PC NG TC + S C C G+ GS C ++ C + C
Sbjct: 1343 GKNVDECLSQPCK-----NGATCKDGANSFRCLCAAGFTGSHCELNINECQ-----SNPC 1392
Query: 2663 SRGATCISLPHGYTCFCPLGTTGIYCE 2689
ATC+ + Y+C C G +G CE
Sbjct: 1393 RNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 55.8 bits (133), Expect = 6e-07
Identities = 55/230 (23%), Positives = 86/230 (37%), Gaps = 52/230 (22%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C N C N C F C+C P + G C ++V CL+ C + + C D + S+ C
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATC-KDGANSFRC 1369
Query: 2938 LCTLGWVGRYCE---NKTSFSTAKFMG------NSYIKYIDPNY---RMRNLQFTTISLN 2985
LC G+ G +CE N+ + + NSY P + R Q T +L+
Sbjct: 1370 LCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLD 1429
Query: 2986 FSTTKTEGLIV---------------WM--------------GIAQNEENDFLAIGLHNQ 3016
F + G ++ WM + +N L +
Sbjct: 1430 FEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYNGW 1489
Query: 3017 TLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQT--LIKAYINNSL 3064
L VN E+I+ S N+G +WHH+ + + K YI+ L
Sbjct: 1490 VL--YVNGREKITNCPSVNDG-----RWHHIAITWTSANGIWKVYIDGKL 1532
Score = 55.1 bits (131), Expect = 1e-06
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 15/104 (14%)
Query: 936 PCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPG 995
PC+N G C C+C + G CE + C I PCL+ CV Y C C PG
Sbjct: 3475 PCQNGGIC---QRPNACSCPEGWMGRLCEEPI--C-ILPCLNGGRCVAP---YQCDCPPG 3525
Query: 996 YTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 1039
+TG C + C S PCL+ G C + C C S + G +C
Sbjct: 3526 WTGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 51.6 bits (122), Expect = 1e-05
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 5/96 (5%)
Query: 2598 GHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHD 2657
GH + C C N GTC + G C C G+ G C + C P
Sbjct: 1181 GHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLP- 1239
Query: 2658 PPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
C C L + C CP G TG CE+ ++
Sbjct: 1240 ----CLNNGVCKDLVGEFICECPSGYTGQRCEENIN 1271
Score = 51.6 bits (122), Expect = 1e-05
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
C + C N+GTC C CP Y+G C+ C PC N C G + +C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVG-EFIC 1255
Query: 2397 LCPYGRSGPLCTDAIN 2412
CP G +G C + IN
Sbjct: 1256 ECPSGYTGQRCEENIN 1271
Score = 51.6 bits (122), Expect = 1e-05
Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 43/183 (23%)
Query: 1066 SCDADGTSTQCKIKINDCTSIPC---------MNEGFCQKSAHGFTCICPRGYT-----G 1111
+C+ D T TQ K C I C + G + T C GY
Sbjct: 3397 TCNPDETWTQTSAK---CEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLR 3453
Query: 1112 AYCEKSIDNCAEPELNSVI---CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSS 1168
+ C ++ + P +V C NGGIC C C G+ G+ CE I
Sbjct: 3454 SVCLENGTWTSPPICRAVCRFPCQNGGICQRPNA----CSCPEGWMGRLCEEPI---CIL 3506
Query: 1169 PCLHGADCEDHINGYVCKCQPGWSGHHCE---------NELECI-PNSCVHELCMENEPG 1218
PCL+G C + Y C C PGW+G C N +C+ PN C C+ + G
Sbjct: 3507 PCLNGGRC---VAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRC---HCLSSWTG 3560
Query: 1219 STC 1221
C
Sbjct: 3561 HNC 3563
Score = 51.6 bits (122), Expect = 1e-05
Identities = 37/105 (35%), Positives = 50/105 (47%), Gaps = 16/105 (15%)
Query: 859 PCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRP 918
PC+N C C C E + G+ CE + C+ L C + G C V ++C C P
Sbjct: 3475 PCQNGGIC----QRPNACSCPEGWMGRLCEEPI--CI-LPCLNGGRC---VAPYQCDCPP 3524
Query: 919 GFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 963
G++GS C + C S PC N G CV NR C+C + G C
Sbjct: 3525 GWTGSRCHTAV--CQS-PCLNGGKCV-RPNR--CHCLSSWTGHNC 3563
Score = 51.2 bits (121), Expect = 2e-05
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQ 2931
+ D C C N G C F C C + G C ++++ C ++ CL++ +C+ D
Sbjct: 1229 ETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICV-DG 1287
Query: 2932 SFSYSCLCTLGWVGRYCENKTS 2953
Y C C G+VG +CE + +
Sbjct: 1288 VAGYRCTCVKGFVGLHCETEVN 1309
Score = 51.2 bits (121), Expect = 2e-05
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
CS + C N G C + C C +G+ G C E ++ C C C+
Sbjct: 1235 CSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSS-----PCLNKGICVDGVA 1289
Query: 2674 GYTCFCPLGTTGIYCE 2689
GY C C G G++CE
Sbjct: 1290 GYRCTCVKGFVGLHCE 1305
Score = 50.8 bits (120), Expect = 2e-05
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 8/84 (9%)
Query: 2326 RHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNG 2383
R GKN++ C C+N TC + C C ++G C+ C++NPC N
Sbjct: 1341 RCGKNVDEC-----LSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQ 1395
Query: 2384 ATCVPKSGTDIVCLCPYGRSGPLC 2407
ATCV + + C C G SG C
Sbjct: 1396 ATCVDELNS-YSCKCQPGFSGKRC 1418
Score = 50.4 bits (119), Expect = 3e-05
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 10/84 (11%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
V +C ++PC N C + C C G+ G+ C + V C + C G
Sbjct: 1308 VNECQSNPCL-----NNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQ-----PCKNG 1357
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
ATC + + C C G TG +CE
Sbjct: 1358 ATCKDGANSFRCLCAAGFTGSHCE 1381
Score = 48.9 bits (115), Expect = 8e-05
Identities = 29/80 (36%), Positives = 35/80 (43%), Gaps = 5/80 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTD-IV 2395
C + C NN C C+CP + G C C + PC NGATC K G +
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATC--KDGANSFR 1368
Query: 2396 CLCPYGRSGPLCTDAINITQ 2415
CLC G +G C IN Q
Sbjct: 1369 CLCAAGFTGSHCELNINECQ 1388
Score = 48.1 bits (113), Expect = 1e-04
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 10/84 (11%)
Query: 2605 SVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
++ +C +SPC N G C++ C C G+ G C V+ C + C
Sbjct: 1269 NINECSSSPCL-----NKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ-----SNPCLN 1318
Query: 2665 GATCISLPHGYTCFCPLGTTGIYC 2688
A C G+ C CP G G C
Sbjct: 1319 NAVCEDQVGGFLCKCPPGFLGTRC 1342
Score = 47.0 bits (110), Expect = 3e-04
Identities = 50/189 (26%), Positives = 72/189 (38%), Gaps = 33/189 (17%)
Query: 230 NKRENWDEQAYECV---CHPPFTGKNCSEI-----IGQCQPHVCFHGNCSNITSNSFICE 281
N E W + + +C C PP +N G + C+ G S E
Sbjct: 3399 NPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLE 3458
Query: 282 CDEQFSGPFCEVSAK-PCVSLLFWKRGIC--PNSSSAYTYECPKGSSSQNGETDVSEFSL 338
S P C + PC + GIC PN+ S CP+G + E + +
Sbjct: 3459 NGTWTSPPICRAVCRFPCQN-----GGICQRPNACS-----CPEGWMGRLCEEPIC---I 3505
Query: 339 VPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCIS 398
+PC NG C+ C C P +T C + C+S P N KC + C C+S
Sbjct: 3506 LPCLNGGRCVA---PYQCDCPPGWTGSRCHT--AVCQS-PCLNGG---KCVRPNRCHCLS 3556
Query: 399 GFTEKNCEK 407
+T NC +
Sbjct: 3557 SWTGHNCSR 3565
Score = 45.8 bits (107), Expect = 7e-04
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%)
Query: 990 CLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSN 1049
C C G+ G CE + C+ PCL+ G C+ Y CDC G+ G+ C T +
Sbjct: 3488 CSCPEGWMGRLCEEPI--CIL-PCLNGGRCVAP---YQCDCPPGWTGSRCHTAV---CQS 3538
Query: 1050 PCLHGRCTELINEYPCSCDADGTSTQCKIK 1079
PCL+G + + C C + T C K
Sbjct: 3539 PCLNG--GKCVRPNRCHCLSSWTGHNCSRK 3566
Score = 45.4 bits (106), Expect = 9e-04
Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
C+ C NNG C CECP Y+G+ C+ C ++PC N CV C
Sbjct: 1235 CSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICV-DGVAGYRC 1293
Query: 2397 LCPYGRSGPLCTDAINITQ 2415
C G G C +N Q
Sbjct: 1294 TCVKGFVGLHCETEVNECQ 1312
Score = 44.3 bits (103), Expect = 0.002
Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
C NGG C C+C GW G C E + C G C++ Y C
Sbjct: 3476 CQNGGICQRPNA---CSCPEGWMGRLCEEPICILP--------CLNGGRCVA---PYQCD 3521
Query: 2679 CPLGTTGIYCEQAL 2692
CP G TG C A+
Sbjct: 3522 CPPGWTGSRCHTAV 3535
Score = 43.9 bits (102), Expect = 0.003
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 2/72 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C +N C N G C G + C C + G C + C CL+ +C D + C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVC-KDLVGEFIC 1255
Query: 2938 LCTLGWVGRYCE 2949
C G+ G+ CE
Sbjct: 1256 ECPSGYTGQRCE 1267
Score = 43.5 bits (101), Expect = 0.003
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRS 2403
C+N G C N C CP + G+LC+ C PC NG CV C CP G +
Sbjct: 3476 CQNGGICQRPNA---CSCPEGWMGRLCEEPIC-ILPCLNGGRCV----APYQCDCPPGWT 3527
Query: 2404 GPLCTDAI 2411
G C A+
Sbjct: 3528 GSRCHTAV 3535
Score = 43.5 bits (101), Expect = 0.003
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 15/83 (18%)
Query: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINK 231
+ C+E + C G+C++ Y C C P ++G C A PC N G C+
Sbjct: 3497 RLCEEPICILPCLNGGRCVAP-----YQCDCPPGWTGSRCH--TAVCQSPCLNGGKCVRP 3549
Query: 232 RENWDEQAYECVCHPPFTGKNCS 254
C C +TG NCS
Sbjct: 3550 N--------RCHCLSSWTGHNCS 3564
Score = 43.1 bits (100), Expect = 0.004
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW 2943
C NGG C + C C P W G+ C+ +V + CL+ C+ C C W
Sbjct: 3508 CLNGGRCVA---PYQCDCPPGWTGSRCHTAV--CQSPCLNGGKCVRPN----RCHCLSSW 3558
Query: 2944 VGRYCENK 2951
G C K
Sbjct: 3559 TGHNCSRK 3566
Score = 42.7 bits (99), Expect = 0.006
Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Query: 680 IDIDECA-SHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSC 719
+D+DECA C A+C++ G+Y C CVPP+ DG +C
Sbjct: 1744 LDVDECAVGSDCSEHASCLNVDGSYICSCVPPY-TGDGKNC 1783
Score = 41.2 bits (95), Expect = 0.016
Identities = 34/128 (26%), Positives = 45/128 (35%), Gaps = 19/128 (14%)
Query: 2587 DGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT 2646
+G F G HP R Q +A + C GT +G+ C++ + +F
Sbjct: 1112 EGKFSRSGLMPCHP-CPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSS-FSSTFSA 1169
Query: 2647 ETVSTCDPE---HDPPHH--------------CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
S P H H C TC L GY C CPLG TG+ CE
Sbjct: 1170 AEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCE 1229
Query: 2690 QALSISDP 2697
+ P
Sbjct: 1230 TDIDECSP 1237
Score = 40.4 bits (93), Expect = 0.028
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Query: 939 NNGTCVDLTNRFFCNCEPEYHG--PFCELDVNKCKI-SPCLDEENCVYRTDGYNCLCAPG 995
NNG + +R FC ++G P C LDV++C + S C + +C+ Y C C P
Sbjct: 1717 NNGYYLLGDSRMFCTDNGSWNGVSPSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVPP 1775
Query: 996 YTG 998
YTG
Sbjct: 1776 YTG 1778
Score = 40.4 bits (93), Expect = 0.028
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 9/65 (13%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW 2943
C+NGG C +C C W G C + + L CL+ C+ Y C C GW
Sbjct: 3476 CQNGGICQRPN---ACSCPEGWMGRLCEEPICILP--CLNGGRCVA----PYQCDCPPGW 3526
Query: 2944 VGRYC 2948
G C
Sbjct: 3527 TGSRC 3531
Score = 39.7 bits (91), Expect = 0.048
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 2334 CHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCV 2387
C P C C N G C++ + C+CP ++G C A C+ +PC NG CV
Sbjct: 3499 CEEPICILP-CLNGGRCVAPYQ---CDCPPGWTGSRCHTAVCQ-SPCLNGGKCV 3547
Score = 38.1 bits (87), Expect = 0.14
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 2372 FASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
F C NPC N TC + G VCLCP G +G C I+ P
Sbjct: 1194 FHECFFNPCHNSGTC-QQLGRGYVCLCPLGYTGLKCETDIDECSP 1237
Score = 37.7 bits (86), Expect = 0.18
Identities = 23/85 (27%), Positives = 31/85 (36%), Gaps = 14/85 (16%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
+G+ P ++ C NGG C+ C+C GW GS C V C G
Sbjct: 3495 MGRLCEEPICILPCLNGGRCV---APYQCDCPPGWTGSRCHTAVCQSP--------CLNG 3543
Query: 2666 ATCISLPHGYTCFCPLGTTGIYCEQ 2690
C+ C C TG C +
Sbjct: 3544 GKCV---RPNRCHCLSSWTGHNCSR 3565
Score = 37.0 bits (84), Expect = 0.31
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 8/50 (16%)
Query: 211 CQELDACSF-KPCKNNGSCINKRENWDEQAYECVCHPPFT--GKNCSEII 257
C ++D C+ C + SC+N + +Y C C PP+T GKNC+E I
Sbjct: 1743 CLDVDECAVGSDCSEHASCLNV-----DGSYICSCVPPYTGDGKNCAEPI 1787
Score = 35.8 bits (81), Expect = 0.69
Identities = 49/218 (22%), Positives = 77/218 (35%), Gaps = 59/218 (27%)
Query: 675 GTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDI 734
G+ + D+ C S+ C G C D+ G+ C+C F C+C GY G
Sbjct: 267 GSFIQDDMVHC-SYLCDEGKDCCDRMGS--CKCGTH---TGHFECICEKGYYG------- 313
Query: 735 DDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQES----NECKMNPCKNNSTCTDLY 790
L Y+C G + + S + C P +N+++
Sbjct: 314 ----------------KGLQYECTACP--SGTYKPEGSPGGISSCIPCPDENHTSPPGST 355
Query: 791 KSYRCECTSGW--TGQNCSEEINECDS-----------DPCMN------GGLCHES-TIP 830
C C G+ +GQ C E+ C + + C N G CH +
Sbjct: 356 SPEDCVCREGYRASGQTC--ELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLV 413
Query: 831 GQFVCLCPP--LYTGQFCHQRYNLCDLLHNPCRNNSTC 866
G + LC P L++G + R C L P + +C
Sbjct: 414 GSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISC 451
Score = 35.4 bits (80), Expect = 0.90
Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 5/40 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C + CHN GTC L G V C CPL +TG CE D
Sbjct: 1197 CFFNPCHNSGTCQQ--LGRGYV---CLCPLGYTGLKCETD 1231
Score = 35.0 bits (79), Expect = 1.2
Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 21/124 (16%)
Query: 1088 CMNEGFCQKSAHG--FTCICPRGYTGAYCEKSIDNCA----EPE-----LNSVICLNGGI 1136
C G C+ H F CIC +GY G + C +PE ++S I
Sbjct: 288 CDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDEN 347
Query: 1137 CVDGPGHTF--DCRCLPGF--SGQFCEININECSSSPCLHG----ADCEDHINGYV-CKC 1187
PG T DC C G+ SGQ CE+ ++ + P +G C +H N +C
Sbjct: 348 HTSPPGSTSPEDCVCREGYRASGQTCEL-VHCPALKPPENGYFIQNTCNNHFNAACGVRC 406
Query: 1188 QPGW 1191
PG+
Sbjct: 407 HPGF 410
Score = 35.0 bits (79), Expect = 1.2
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSF 219
C C+ E +YSC CQP FSGK C+ + F
Sbjct: 1392 CRNQATCVDEL--NSYSCKCQPGFSGKRCETEQSTGF 1426
Score = 34.7 bits (78), Expect = 1.5
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ 2371
C + CRN TC+ + + C+C +SGK C+
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 34.3 bits (77), Expect = 2.0
Identities = 43/195 (22%), Positives = 64/195 (32%), Gaps = 57/195 (29%)
Query: 867 LALVDANQHCICREEFE----------------GKNCEIDVKDCLFLSCQDYGDCEDMV- 909
+A +HC FE G + D+ C +L C + DC D +
Sbjct: 234 MASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYL-CDEGKDCCDRMG 292
Query: 910 --------NNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGP 961
+F CIC G+ G + E C S K G+ +++
Sbjct: 293 SCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISS------------- 339
Query: 962 FCELDVNKCKISPCLDEENC--VYRTDGYNCLCAPGY--TGINCEINLDECLSEPCLHDG 1017
PC DE + T +C+C GY +G CE+ L P +G
Sbjct: 340 ----------CIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPP--ENG 387
Query: 1018 VCIDGI--NHYTCDC 1030
I NH+ C
Sbjct: 388 YFIQNTCNNHFNAAC 402
Score = 33.5 bits (75), Expect = 3.4
Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 5/38 (13%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
C C NG TC G SF+C C FTG CE
Sbjct: 1349 CLSQPCKNGATC-----KDGANSFRCLCAAGFTGSHCE 1381
Score = 33.5 bits (75), Expect = 3.4
Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 2605 SVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVST 2651
++ +C ++PC N TC++ S C C G+ G C ST
Sbjct: 1383 NINECQSNPCR-----NQATCVDELNSYSCKCQPGFSGKRCETEQST 1424
Score = 32.3 bits (72), Expect = 7.6
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 18/77 (23%)
Query: 1144 TFDCR---CLPGFSGQFCEININECSSSP-------CLHGADCEDHIN------GYVCKC 1187
T+ C L G S FC N + SP C G+DC +H + Y+C C
Sbjct: 1713 TYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSC 1772
Query: 1188 QPGWS--GHHCENELEC 1202
P ++ G +C ++C
Sbjct: 1773 VPPYTGDGKNCAEPIKC 1789
Score = 32.0 bits (71), Expect = 9.9
Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 813 CDS--DPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDL-LHNPCRNN---STC 866
CD D C G C T G F C+C Y G+ C + P + S+C
Sbjct: 281 CDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSC 340
Query: 867 LALVDAN----------QHCICREEF--EGKNCEI 889
+ D N + C+CRE + G+ CE+
Sbjct: 341 IPCPDENHTSPPGSTSPEDCVCREGYRASGQTCEL 375
Score = 32.0 bits (71), Expect = 9.9
Identities = 37/140 (26%), Positives = 51/140 (36%), Gaps = 19/140 (13%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFP-SFNGNSYLELPFL 2161
CQ + C N TC + S+ C C F+G+ CE + F F + L
Sbjct: 1387 CQSNPCRNQATC-----VDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVML 1441
Query: 2162 KFVLEKEHNRTVTIYLTIKTNSLNGT-ILYSNGNNCGKQFL------HLFLVEGR----- 2209
+L H T T ++ + GT I Y+ N L + V GR
Sbjct: 1442 DGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITN 1501
Query: 2210 -PSVKYGCGNSQNILTVSAN 2228
PSV G + I SAN
Sbjct: 1502 CPSVNDGRWHHIAITWTSAN 1521
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 228 bits (581), Expect = 7e-59
Identities = 203/737 (27%), Positives = 335/737 (45%), Gaps = 96/737 (13%)
Query: 2428 SFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQK---GHGLN----GDDFLAV 2480
SFL I D +E + F+ + + ++ + GQK G N DF++
Sbjct: 3672 SFLPLPTIKDAYRKFEIKITFRPDS-----ADGMLLYNGQKRVPGSPTNLANRQPDFISF 3726
Query: 2481 GLLNGSVVYSYNLGSGIASIRSEPLNLSLG-VHTVHLGKFFQEGWLKVDDHKNKSIIAPG 2539
GL+ G + ++ GSG+A+IR P L+LG HTV L + +G L V D + + G
Sbjct: 3727 GLVGGRPEFRFDAGSGMATIR-HPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQG 3785
Query: 2540 RLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGH 2599
+ GL++ + Y+GGY +Y +P A +GF GC+ L+++ E+ F L N H
Sbjct: 3786 KFQGLDLNEELYLGGYPDY--GAIPK-AGLSSGFIGCVRELRIQGEEIV-FHDL-NLTAH 3840
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDP 2658
G H C C NGG C +S +S Y C C G+ GS C + + H
Sbjct: 3841 -------GISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQAL----HCH 3889
Query: 2659 PHHCSRGATCISLP--HGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSF-ASFHVR 2715
P C ATC++ P GYTC C LG +G+ CE+ ++++ PS S S+++ A +
Sbjct: 3890 PEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSL-SGAGSYLALPALTNTH 3948
Query: 2716 KKTHIQLQFQPLAADGILFYAAQHLKAQSG---DFLCISLVNSSVQLRYNLGDRTIILET 2772
+ + ++F+PLA DG+L ++ +SG DF+ +++V ++ RY LG +L +
Sbjct: 3949 HELRLDVEFKPLAPDGVLLFSG----GKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRS 4004
Query: 2773 LQKVTINGSTWHIIKAGRVGAEGYLDLDGIN-VTEKASTKMSSLDTNTDFYIGGVSSLNL 2831
+ + + WH + A R+ +G L ++G V + K L+ +T Y+GGV
Sbjct: 4005 AEPLAL--GRWHRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVP 4062
Query: 2832 VNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDC-DGTACGYNTCRNGGEC 2890
++P N F+GC+ +V +N + L LT + G +G C D + C C++G C
Sbjct: 4063 LSPAT--NMSAHFRGCVGEVSVNGKRLDLT-YSFLGSQGIGQCYDSSPCERQPCQHGATC 4119
Query: 2891 TVNGT-TFSCRCLPDWAGNTC--NQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRY 2947
G F C C + G+ C ++ L CLH C + CLC G+ G
Sbjct: 4120 MPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTR-----CLCLPGFSGPR 4174
Query: 2948 CENKTSFSTAK--------------------FMGNSYIKYIDPNYRMRNLQFT--TISLN 2985
C+ + A+ F + ++ + + R+L TI L
Sbjct: 4175 CQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFLAF-PGHVFSRSLPEVPETIELE 4233
Query: 2986 FSTTKTEGLIVWMGIAQNEE---NDFLAIGLHNQTLKIAVNLGE---RISVPMSYNNGTF 3039
T+ GL++W G+ E DF+++GL + L LG R+ N+G
Sbjct: 4234 VRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG-- 4291
Query: 3040 CCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIV 3099
+WH V ++ ++ ++S P N VA+N G Y+GG V +
Sbjct: 4292 ---EWHRVTALREGRRGSIQVDGEELVS-GRSPGPN-VAVNAKGSVYIGG---APDVATL 4343
Query: 3100 TQEIFKTNFVGKIKDVV 3116
T F + G +K++V
Sbjct: 4344 TGGRFSSGITGCVKNLV 4360
Score = 207 bits (527), Expect = 1e-52
Identities = 199/776 (25%), Positives = 331/776 (42%), Gaps = 113/776 (14%)
Query: 2154 SYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYS----------NGNNCGKQFLHL 2203
S+L LP +K + R I +T + +S +G +LY+ N N F+
Sbjct: 3672 SFLPLPTIK-----DAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISF 3726
Query: 2204 FLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGS--PGVVCMIEMTAD 2261
LV GRP ++ G+ + T+ + F +T+ + GS G + + T+
Sbjct: 3727 GLVGGRPEFRFDAGSG--MATIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQ 3784
Query: 2262 GKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFI 2321
GK Q D E ++LG P I KAG GF GC+ +L++ +E
Sbjct: 3785 GK--FQGLDLN---------EELYLGGYPDYGAI-PKAGLSSGFIGCVRELRIQGEEIVF 3832
Query: 2322 IDEARHGKNIENCHVPWCAHHLCRNNGTCI-SDNENLFCECPRLYSGKLCQFAS---CEN 2377
D I +C P C C+N G C S++ + C CP ++G C+ + C
Sbjct: 3833 HDLNLTAHGISHC--PTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHP 3890
Query: 2378 NPCGNGATCVPK-SGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRIS 2436
CG ATCV + G C C GRSG C + + +T P SG S+LA ++
Sbjct: 3891 EACGPDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAG-----SYLALPALT 3945
Query: 2437 DISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSG 2496
+ H+E L + + ++ F+G K + +DF+++ ++ G + + Y LGSG
Sbjct: 3946 NT--HHELRLDVEFK---PLAPDGVLLFSGGKSGPV--EDFVSLAMVGGHLEFRYELGSG 3998
Query: 2497 IASIRS-EPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGY 2555
+A +RS EPL L H V + ++G L+V+ + +PG+ GLN+ + Y+GG
Sbjct: 3999 LAVLRSAEPLALGRW-HRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGV 4057
Query: 2556 SEYTPDLLPNGADFKNGFQGCIFTLQVRTEK-DGHFRGLGNPEGHPNAGRSVGQCH-ASP 2613
P L + F+GC+ + V ++ D + LG+ + +GQC+ +SP
Sbjct: 4058 EPSVP--LSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGS--------QGIGQCYDSSP 4107
Query: 2614 CSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP 2672
C C +G TC+ +G + C C G+KG C + C C G TC
Sbjct: 4108 CERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREP----CLHGGTC---- 4159
Query: 2673 HGYTCFCPLGTTGIYCEQALS--ISDPSFR-----SNELSWMSFASFH------------ 2713
G C C G +G C+Q I++ + N+ A FH
Sbjct: 4160 QGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFLAFPGHVF 4219
Query: 2714 ----VRKKTHIQLQFQPLAADGILFYAAQHL--KAQSGDFLCISLVNSSVQLRYNLGDRT 2767
I+L+ + A G+L + + Q DF+ + L + + RY LG
Sbjct: 4220 SRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGE 4279
Query: 2768 IILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGIN-VTEKASTKMSSLDTNTDFYIGGV 2826
L + + IN WH + A R G G + +DG V+ ++ +++ YIGG
Sbjct: 4280 ARL--VSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGA 4337
Query: 2827 SSLNLVNPMAIENEPVGFQGCIRQVIINN--------QELQLTEFGAKGGSNVGDC 2874
+ + + G GC++ +++++ Q L L + A+ G+N C
Sbjct: 4338 PDVATLTGGRFSS---GITGCVKNLVLHSARPGAPPPQPLDL-QHRAQAGANTRPC 4389
Score = 116 bits (290), Expect = 4e-25
Identities = 151/610 (24%), Positives = 242/610 (39%), Gaps = 72/610 (11%)
Query: 2013 VFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSP 2072
+++GG+PD +G I F GC+ + I +H N + G P
Sbjct: 3796 LYLGGYPD-YGAIPKAGLSSGFIGCVRELRIQGEEIV--------FHDLNLTAHGISHCP 3846
Query: 2073 TASFVDASDVTQGVDTMWTS---VSPSVAAPSVCQQ--------DVCHNGGTCHAIFLSS 2121
T + Q D+ +S V P+ S C+ + C TC
Sbjct: 3847 TCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGR 3906
Query: 2122 GIVSFQCDCPLHFTGRFCEKDAGLFFPSFNG-NSYLELPFLKFVLEKEHNRTVTIYLTIK 2180
G + C C L +G CE+ + PS +G SYL LP L H+ + + + K
Sbjct: 3907 G---YTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALP----ALTNTHHE-LRLDVEFK 3958
Query: 2181 TNSLNGTILYSNGNNCG-KQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPI 2239
+ +G +L+S G + + F+ L +V G +Y G+ +L + P+
Sbjct: 3959 PLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVL----------RSAEPL 4008
Query: 2240 TIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKA 2299
+ V + + + +G PV + S + ++LG + +V +
Sbjct: 4009 ALGRWHRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLH-TLLYLGGVEPSVPLSPAT 4067
Query: 2300 GPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPW-CAHHLCRNNGTCISDNENLF 2358
FRGC+ ++ VN K + + I C+ C C++ TC+ E F
Sbjct: 4068 NMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEF 4127
Query: 2359 -CECPRLYSGKLCQFAS--CE-NNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN-- 2412
C C + G LC+ C+ PC +G TC GT CLC G SGP C
Sbjct: 4128 QCLCRDGFKGDLCEHEENPCQLREPCLHGGTC---QGTR--CLCLPGFSGPRCQQGSGHG 4182
Query: 2413 ITQPRF-----SGTDAFGY-------TSFLAYSRISDISFHYEFHLKFQLANNHSALQNN 2460
I + + G DA G FLA+ E +L S
Sbjct: 4183 IAESDWHLEGSGGNDAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGL 4242
Query: 2461 LIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSE-PLNLSLGVHTVHLGKF 2519
L++ + G G DF+++GL +G +V+ Y LGSG A + SE P+N H V +
Sbjct: 4243 LLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPIN-DGEWHRVTALRE 4301
Query: 2520 FQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLP-NGADFKNGFQGCIF 2578
+ G ++VD + S +PG V +N Y+GG PD+ G F +G GC+
Sbjct: 4302 GRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGG----APDVATLTGGRFSSGITGCVK 4357
Query: 2579 TLQVRTEKDG 2588
L + + + G
Sbjct: 4358 NLVLHSARPG 4367
Score = 63.5 bits (153), Expect = 3e-09
Identities = 58/233 (24%), Positives = 84/233 (36%), Gaps = 45/233 (19%)
Query: 913 RCICRPGFSGSLCEIEINECSSEPCKN-NGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK 971
+C C PG+ G C+ +C + + +G + R C+C H CE + C
Sbjct: 1125 QCSCPPGYRGPSCQ----DCDTGYTRTPSGLYLGTCER--CSCHG--HSEACEPETGAC- 1175
Query: 972 ISPCLDEENCVYRTDGYNC-LCAPGYTGINCEINLDECLSEPCLHDGVC--------IDG 1022
+ C + T+G C C PGY G +C PC D +D
Sbjct: 1176 -------QGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDT 1228
Query: 1023 INHYTCD-CKSGFFGTHCETNANDCLSNPCLHGRC---TELINEYPCSCDADGT------ 1072
H TCD C G G HCE A NP C +++ C+CD G+
Sbjct: 1229 DGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD 1288
Query: 1073 ---STQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCA 1122
QCK ++ T C F +++ P G +C CA
Sbjct: 1289 AAGQCQCKAQVEGLTCSHCRPHHFHLSASN------PDGCLPCFCMGITQQCA 1335
Score = 59.3 bits (142), Expect = 6e-08
Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECS-SSPCLHGADCEDHINGYVCKCQP 1189
C +G C+ + F C C GF G CE N C PCLHG C+ G C C P
Sbjct: 4113 CQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQ----GTRCLCLP 4168
Query: 1190 GWSGHHCE 1197
G+SG C+
Sbjct: 4169 GFSGPRCQ 4176
Score = 58.2 bits (139), Expect = 1e-07
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 10/114 (8%)
Query: 724 GYVGIRCEQDIDDCILNACEHNSTCKDL-HLSYQCVCLSDWEGNFCEQESNECKM-NPCK 781
G GI D C C+H +TC +QC+C ++G+ CE E N C++ PC
Sbjct: 4095 GSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCL 4154
Query: 782 NNSTCTDLYKSYRCECTSGWTGQNCSEEINE--CDSDPCMNGGLCHESTIPGQF 833
+ TC + RC C G++G C + +SD + G +++ PGQ+
Sbjct: 4155 HGGTC----QGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDA--PGQY 4202
Score = 57.8 bits (138), Expect = 2e-07
Identities = 35/94 (37%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 1083 CTSIPCMNEGFCQKS-AHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGP 1141
C PC N G C S + + C+CP G+TG+ CE S PE C CV+ P
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPE----ACGPDATCVNRP 3903
Query: 1142 -GHTFDCRCLPGFSGQFCEININECSSSPCLHGA 1174
G + CRC G SG CE + ++P L GA
Sbjct: 3904 DGRGYTCRCHLGRSGLRCEEGVT--VTTPSLSGA 3935
Score = 56.2 bits (134), Expect = 5e-07
Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 771 ESNECKMNPCKNNSTCTDLYK-SYRCECTSGWTGQNCSEEINECD-SDPCMNGGLCHEST 828
+S+ C+ PC++ +TC + ++C C G+ G C E N C +PC++GG C +
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTR 4163
Query: 829 IPGQFVCLCPPLYTGQFCHQ 848
CLC P ++G C Q
Sbjct: 4164 ------CLCLPGFSGPRCQQ 4177
Score = 55.8 bits (133), Expect = 6e-07
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 5/106 (4%)
Query: 822 GLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREE 881
G E ++ G+ + L Q Q Y+ PC++ +TC+ + C+CR+
Sbjct: 4075 GCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDG 4134
Query: 882 FEGKNCEIDVKDC-LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCE 926
F+G CE + C L C G C+ RC+C PGFSG C+
Sbjct: 4135 FKGDLCEHEENPCQLREPCLHGGTCQ----GTRCLCLPGFSGPRCQ 4176
Score = 55.8 bits (133), Expect = 6e-07
Identities = 36/142 (25%), Positives = 53/142 (37%), Gaps = 30/142 (21%)
Query: 876 CICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSE 935
C+ GK ++ FL Q G C D + C +
Sbjct: 4076 CVGEVSVNGKRLDLTYS---FLGSQGIGQCYDS---------------------SPCERQ 4111
Query: 936 PCKNNGTCVDLTN-RFFCNCEPEYHGPFCELDVNKCKI-SPCLDEENCVYRTDGYNCLCA 993
PC++ TC+ F C C + G CE + N C++ PCL C G CLC
Sbjct: 4112 PCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTC----QGTRCLCL 4167
Query: 994 PGYTGINCEINLDECLSEPCLH 1015
PG++G C+ ++E H
Sbjct: 4168 PGFSGPRCQQGSGHGIAESDWH 4189
Score = 53.5 bits (127), Expect = 3e-06
Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 19/97 (19%)
Query: 677 QCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDD 736
QC D C PC++GATC+ G Y F CLC G+ G CE + +
Sbjct: 4101 QC-YDSSPCERQPCQHGATCMPA-GEY------------EFQCLCRDGFKGDLCEHEENP 4146
Query: 737 CIL-NACEHNSTCKDLHLSYQCVCLSDWEGNFCEQES 772
C L C H TC+ +C+CL + G C+Q S
Sbjct: 4147 CQLREPCLHGGTCQ----GTRCLCLPGFSGPRCQQGS 4179
Score = 50.8 bits (120), Expect = 2e-05
Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 13/133 (9%)
Query: 719 CLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMN 778
C C PGY+G+ C+ DC A + T L+L + +C + + C E+ C +
Sbjct: 1530 CRCPPGYIGLSCQ----DC---APGYTRTGSGLYLGHCELCECNGHSDLCHPETGAC--S 1580
Query: 779 PCKNNST---CTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVC 835
C++N+ C Y + T+G T ++C + M C G
Sbjct: 1581 QCQHNAAGEFCELCAPGYYGDATAG-TPEDCQPCACPLTNPENMFSRTCESLGAGGYRCT 1639
Query: 836 LCPPLYTGQFCHQ 848
C P YTGQ+C Q
Sbjct: 1640 ACEPGYTGQYCEQ 1652
Score = 50.4 bits (119), Expect = 3e-05
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 20/92 (21%)
Query: 643 DTEDCKSASCKNGTTSTHLRGYFFR-KCVPGFKGTQCEIDIDECA-SHPCKNGATCIDQP 700
D+ C+ C++G T Y F+ C GFKG CE + + C PC +G TC
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTC---- 4159
Query: 701 GNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQ 732
G CLC PG+ G RC+Q
Sbjct: 4160 --------------QGTRCLCLPGFSGPRCQQ 4177
Score = 50.1 bits (118), Expect = 4e-05
Identities = 35/116 (30%), Positives = 48/116 (41%), Gaps = 11/116 (9%)
Query: 940 NGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD-GYNCLCAPGYTG 998
NG +DLT F + G D + C+ PC C+ + + CLC G+ G
Sbjct: 4083 NGKRLDLTYSFLGS-----QGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKG 4137
Query: 999 INCEINLDEC-LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH 1053
CE + C L EPCLH G C C C GF G C+ + ++ H
Sbjct: 4138 DLCEHEENPCQLREPCLHGGTC----QGTRCLCLPGFSGPRCQQGSGHGIAESDWH 4189
Score = 48.9 bits (115), Expect = 8e-05
Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 13/90 (14%)
Query: 1165 CSSSPCLHGADCED-HINGYVCKCQPGWSGHHCENE--LECIPNSCVHELCMENEP---G 1218
C PC +G C D + YVC C G++G CE+ L C P +C + N P G
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRG 3907
Query: 1219 STCLCTPGFMTCSIGLLCGDEIRRITCLTP 1248
TC C G GL C + +T TP
Sbjct: 3908 YTCRCHLG----RSGLRCEE---GVTVTTP 3930
Score = 48.9 bits (115), Expect = 8e-05
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 4/75 (5%)
Query: 932 CSSEPCKNNGTCVDL-TNRFFCNCEPEYHGPFCE-LDVNKCKISPCLDEENCVYRTD--G 987
C PC+N G C D ++ + C C + G CE C C + CV R D G
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRG 3907
Query: 988 YNCLCAPGYTGINCE 1002
Y C C G +G+ CE
Sbjct: 3908 YTCRCHLGRSGLRCE 3922
Score = 48.5 bits (114), Expect = 1e-04
Identities = 26/70 (37%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCE-ININECSSSPCLHGADCEDHIN--GYVCKC 1187
C NGG C D ++ C C GF+G CE C C A C + + GY C+C
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCRC 3912
Query: 1188 QPGWSGHHCE 1197
G SG CE
Sbjct: 3913 HLGRSGLRCE 3922
Score = 48.5 bits (114), Expect = 1e-04
Identities = 35/119 (29%), Positives = 49/119 (41%), Gaps = 19/119 (15%)
Query: 1083 CTSIPCMNEGFCQKSA-HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGP 1141
C PC + C + + F C+C G+ G CE + C E CL+GG C
Sbjct: 4108 CERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLRE----PCLHGGTC---- 4159
Query: 1142 GHTFDCRCLPGFSGQFCEININECSSSPCLHG-ADCEDHINGYVCKCQPGWSGHHCENE 1199
C CLPGFSG C+ HG A+ + H+ G PG G + ++
Sbjct: 4160 -QGTRCLCLPGFSGPRCQQGSG--------HGIAESDWHLEGSGGNDAPGQYGAYFHDD 4209
Score = 47.0 bits (110), Expect = 3e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFC-HQRYNLCDLLHNPCRNNSTCLALVD 871
C PC NGG CH+S +VC+CP +TG C H + C C ++TC+ D
Sbjct: 3848 CRDRPCQNGGQCHDSE-SSSYVCVCPAGFTGSRCEHSQALHCH--PEACGPDATCVNRPD 3904
Query: 872 ANQH-CICREEFEGKNCE 888
+ C C G CE
Sbjct: 3905 GRGYTCRCHLGRSGLRCE 3922
Score = 46.6 bits (109), Expect = 4e-04
Identities = 48/180 (26%), Positives = 60/180 (33%), Gaps = 40/180 (22%)
Query: 914 CICRPGFSGSLCEI------------EINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGP 961
C C G+SG CE + CS C + + D NC+ GP
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGP 790
Query: 962 FC------------ELDVNKCKISPC--LD-----EENCVYRTDGY-NC-LCAPGYTGIN 1000
C + C+ PC +D + C TDG C CAPGYTG
Sbjct: 791 QCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRR 850
Query: 1001 CEINLDECLSEPCLHDGVCIDGINHYTCDC-KSGFFGT-----HCETNANDCLSNPCLHG 1054
CE P G C +N C + G GT C+ N L N C G
Sbjct: 851 CESCAPGYEGNPIQPGGKC-RPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Score = 46.2 bits (108), Expect = 5e-04
Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 970 CKISPCLDEENCV-YRTDGYNCLCAPGYTGINCEINLD-ECLSEPCLHDGVCI---DGIN 1024
C+ PC + C + Y C+C G+TG CE + C E C D C+ DG
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDG-R 3906
Query: 1025 HYTCDCKSGFFGTHCETNANDCLSNPCLHG 1054
YTC C G G CE ++ P L G
Sbjct: 3907 GYTCRCHLGRSGLRCEEGVT--VTTPSLSG 3934
Score = 46.2 bits (108), Expect = 5e-04
Identities = 24/62 (38%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 995 GYTGINCEINLDECLSEPCLHDGVCID-GINHYTCDCKSGFFGTHCETNANDC-LSNPCL 1052
G GI + C +PC H C+ G + C C+ GF G CE N C L PCL
Sbjct: 4095 GSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCL 4154
Query: 1053 HG 1054
HG
Sbjct: 4155 HG 4156
Score = 45.4 bits (106), Expect = 9e-04
Identities = 48/209 (22%), Positives = 76/209 (36%), Gaps = 38/209 (18%)
Query: 589 RCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCK 648
+CSC Y G C C ++ + GL L C+C G CE +T C+
Sbjct: 1125 QCSCPPGYRGPSC----QDCDTGYTRTPSGLYLGTCERCSCHG----HSEACEPETGACQ 1176
Query: 649 SASCKNGTTSTHLRGYFFRKCVPGF-----KGTQCEIDIDECASHPCKNGA--TC-IDQP 700
C++ H G +C PG+ +GT + + C P A TC +D
Sbjct: 1177 G--CQH-----HTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTD 1229
Query: 701 GNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCL 760
G+ C C+PG+ G CE+ N + +D + C
Sbjct: 1230 GHPTCDA-------------CSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCN 1276
Query: 761 SDWEGNFCEQ--ESNECKMNPCKNNSTCT 787
D +G+ Q + +C+ TC+
Sbjct: 1277 CDPQGSVSSQCDAAGQCQCKAQVEGLTCS 1305
Score = 44.3 bits (103), Expect = 0.002
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDA--CSFKPCKNNGSCINKRENWDEQAY 240
C G+C ++ S +Y C C F+G C+ A C + C + +C+N+ D + Y
Sbjct: 3853 CQNGGQC-HDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRP---DGRGY 3908
Query: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGN 269
C CH +G C E + P + G+
Sbjct: 3909 TCRCHLGRSGLRCEEGVTVTTPSLSGAGS 3937
Score = 43.5 bits (101), Expect = 0.003
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 9/83 (10%)
Query: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQ-PHVCFHGN 269
C + C +PC++ +C+ E ++C+C F G C CQ C HG
Sbjct: 4102 CYDSSPCERQPCQHGATCMPA----GEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGG 4157
Query: 270 CSNITSNSFICECDEQFSGPFCE 292
T C C FSGP C+
Sbjct: 4158 ----TCQGTRCLCLPGFSGPRCQ 4176
Score = 43.5 bits (101), Expect = 0.003
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 1165 CSSSPCLHGADCEDHIN-GYVCKCQPGWSGHHCENELECIPNSC-VHELCMENEP--GST 1220
C PC HGA C + C C+ G+ G CE+E N C + E C+ G+
Sbjct: 4108 CERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHE----ENPCQLREPCLHGGTCQGTR 4163
Query: 1221 CLCTPGF 1227
CLC PGF
Sbjct: 4164 CLCLPGF 4170
Score = 43.1 bits (100), Expect = 0.004
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 45/165 (27%)
Query: 889 IDVKDC------LFLSCQD-------------YGDCEDMVNNFRCICRPGFSGSLCEIEI 929
++V++C + LSCQD G CE +C LC E
Sbjct: 1525 LEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCE--------LCECNGHSDLCHPET 1576
Query: 930 NECSSEPCKNNGTCVDLTNRFFCN-CEPEYHGPFCELDVNKCKISPC--LDEENCVYRT- 985
CS C++N FC C P Y+G C+ C + EN RT
Sbjct: 1577 GACSQ--CQHNAAGE------FCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTC 1628
Query: 986 -----DGYNCL-CAPGYTGINCEINLDECLSEPCLHDGVCIDGIN 1024
GY C C PGYTG CE + P + G C+ N
Sbjct: 1629 ESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETN 1673
Score = 42.7 bits (99), Expect = 0.006
Identities = 42/158 (26%), Positives = 57/158 (36%), Gaps = 18/158 (11%)
Query: 1028 CDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIP 1087
C C G+ G C+ DC G L + C C+ G S C + C+
Sbjct: 1530 CRCPPGYIGLSCQ----DCAPGYTRTGSGLYLGHCELCECN--GHSDLCHPETGACSQ-- 1581
Query: 1088 CMNEGFCQKSAHGFTC-ICPRGYTG---AYCEKSIDNCAEPELNSVICLNGGICVDGPGH 1143
CQ +A G C +C GY G A + CA P N + G G
Sbjct: 1582 ------CQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGG 1635
Query: 1144 TFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHIN 1181
C PG++GQ+CE +P + G C N
Sbjct: 1636 YRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETN 1673
Score = 42.4 bits (98), Expect = 0.007
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
Query: 737 CILNACEHNSTCKDLHLS-YQCVCLSDWEGNFCE-QESNECKMNPCKNNSTCTDL--YKS 792
C C++ C D S Y CVC + + G+ CE ++ C C ++TC + +
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRG 3907
Query: 793 YRCECTSGWTGQNCSEEI 810
Y C C G +G C E +
Sbjct: 3908 YTCRCHLGRSGLRCEEGV 3925
Score = 42.0 bits (97), Expect = 0.010
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 7/79 (8%)
Query: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIG-QCQPHVCF-HGNCSN-I 273
C +PC+N G C + + +Y CVC FTG C C P C C N
Sbjct: 3848 CRDRPCQNGGQCHDS----ESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRP 3903
Query: 274 TSNSFICECDEQFSGPFCE 292
+ C C SG CE
Sbjct: 3904 DGRGYTCRCHLGRSGLRCE 3922
Score = 41.2 bits (95), Expect = 0.016
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 14/90 (15%)
Query: 647 CKSASCKNGTTSTHLRGY-FFRKCVPGFKGTQCE-IDIDECASHPCKNGATCIDQPGNYF 704
C+ C+NG + C GF G++CE C C ATC+++P
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGR- 3906
Query: 705 CQCVPPFKVVDGFSCLCNPGYVGIRCEQDI 734
G++C C+ G G+RCE+ +
Sbjct: 3907 -----------GYTCRCHLGRSGLRCEEGV 3925
Score = 40.8 bits (94), Expect = 0.021
Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 21/155 (13%)
Query: 642 IDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPG 701
++ E+C+ C G G + C PG+ T + + C C NG + + P
Sbjct: 1525 LEVEECR---CPPGYI-----GLSCQDCAPGYTRTGSGLYLGHCELCEC-NGHSDLCHPE 1575
Query: 702 NYFC-QCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACE-------HNSTCKDLHL 753
C QC F LC PGY G +DC AC + TC+ L
Sbjct: 1576 TGACSQC--QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGA 1633
Query: 754 -SYQC-VCLSDWEGNFCEQESNECKMNPCKNNSTC 786
Y+C C + G +CEQ NP C
Sbjct: 1634 GGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 40.4 bits (93), Expect = 0.028
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Query: 1042 NANDCLSNPCLHGRCTELINEY--PCSCDADGTSTQCKIKINDC-TSIPCMNEGFCQKSA 1098
+++ C PC HG EY C C C+ + N C PC++ G CQ
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQ--- 4160
Query: 1099 HGFTCICPRGYTGAYCEK 1116
G C+C G++G C++
Sbjct: 4161 -GTRCLCLPGFSGPRCQQ 4177
Score = 40.0 bits (92), Expect = 0.036
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 11/72 (15%)
Query: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFK-PCKNNGSCINKRENWDEQAYECV 243
HG A + C C+ F G C+ E + C + PC + G+C Q C+
Sbjct: 4115 HGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTC---------QGTRCL 4165
Query: 244 CHPPFTGKNCSE 255
C P F+G C +
Sbjct: 4166 CLPGFSGPRCQQ 4177
Score = 39.7 bits (91), Expect = 0.048
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 6/82 (7%)
Query: 332 DVSEFSLVPCQNGTDCIKISN-DVMCICSPIFTDLLCKSIQTSCE-SFPLRNNATCKKCE 389
D S PCQ+G C+ + C+C F LC+ + C+ P + TC+
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTR 4163
Query: 390 KDYPCSCISGFTEKNCEKAIDH 411
C C+ GF+ C++ H
Sbjct: 4164 ----CLCLPGFSGPRCQQGSGH 4181
Score = 39.3 bits (90), Expect = 0.062
Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 2/76 (2%)
Query: 775 CKMNPCKNNSTCTDLYKS-YRCECTSGWTGQNCS-EEINECDSDPCMNGGLCHESTIPGQ 832
C+ PC+N C D S Y C C +G+TG C + C + C C
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRG 3907
Query: 833 FVCLCPPLYTGQFCHQ 848
+ C C +G C +
Sbjct: 3908 YTCRCHLGRSGLRCEE 3923
Score = 38.9 bits (89), Expect = 0.081
Identities = 38/139 (27%), Positives = 50/139 (35%), Gaps = 28/139 (20%)
Query: 990 CLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSN 1049
C C PGY G++C+ +C G G Y C+ CE N + L +
Sbjct: 1530 CRCPPGYIGLSCQ----DCAP------GYTRTGSGLYLGHCEL------CECNGHSDLCH 1573
Query: 1050 P-------CLHGRCTELINEYPCSCDAD---GTSTQCKIKINDCTSIPCMNEGFCQK-SA 1098
P C H E D GT C+ T+ M C+ A
Sbjct: 1574 PETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGA 1633
Query: 1099 HGFTCI-CPRGYTGAYCEK 1116
G+ C C GYTG YCE+
Sbjct: 1634 GGYRCTACEPGYTGQYCEQ 1652
Score = 37.4 bits (85), Expect = 0.24
Identities = 51/206 (24%), Positives = 68/206 (33%), Gaps = 58/206 (28%)
Query: 990 CLCAPGYTGINCEI------------NLDECLSEPCLHDGVCIDGI-------NHYT--- 1027
C C GY+G++CE L C C D + H T
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGP 790
Query: 1028 -CD-CKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTS 1085
C+ CK+GFFG + A C PC + + ++ C D DG +T
Sbjct: 791 QCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSD-TCFLDTDGQAT----------- 838
Query: 1086 IPCMNEGFCQKSAHGFT---C-ICPRGYTGAYCEKSIDNCAEPELNSVIC-LNGGICVDG 1140
C A G+T C C GY G + C V C G + G
Sbjct: 839 --------CDACAPGYTGRRCESCAPGYEGNPIQPG-GKCRPVNQEIVRCDERGSMGTSG 889
Query: 1141 PGHTFDCRCLPGFSGQFCEININECS 1166
CRC G+ C NEC+
Sbjct: 890 EA----CRCKNNVVGRLC----NECA 907
Score = 37.4 bits (85), Expect = 0.24
Identities = 52/227 (22%), Positives = 81/227 (35%), Gaps = 48/227 (21%)
Query: 668 KCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVG 727
+C G+ G CE C +H + G Y C C CN G+
Sbjct: 732 RCPIGYSGLSCE----SCDAHFTRVPG------GPYLGTCS---------GCNCN-GHAS 771
Query: 728 IRCEQDIDDCILNACEHNSTCKDLHLSYQC-VCLSDWEGNFCEQESNECKMNPC------ 780
C+ C+ C+HN+ QC C + + G+ + + C+ PC
Sbjct: 772 -SCDPVYGHCL--NCQHNTE------GPQCNKCKAGFFGDAMKATATSCRPCPCPYIDAS 822
Query: 781 -KNNSTC-TDLYKSYRCE-CTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLC 837
+ + TC D C+ C G+TG+ C + +P GG C Q + C
Sbjct: 823 RRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRP---VNQEIVRC 879
Query: 838 PPL----YTGQFCHQRYNLCDLLHNPCRNNSTCLAL--VDANQHCIC 878
+G+ C + N+ L N C + S L+ D C C
Sbjct: 880 DERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 37.4 bits (85), Expect = 0.24
Identities = 48/206 (23%), Positives = 69/206 (33%), Gaps = 64/206 (31%)
Query: 719 CLCNPGYVGIRCEQDIDD--------CILNACE------HNSTCKDLHLSYQCVCLSDWE 764
C C PGY G C QD D L CE H+ C+ + Q C E
Sbjct: 1126 CSCPPGYRGPSC-QDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQG-CQHHTE 1183
Query: 765 GNFCEQ------------ESNECKMNPCKNNS-------TC---TDLYKSYRCE-CTSGW 801
G CEQ +C++ PC + TC TD + + C+ C+ G
Sbjct: 1184 GPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPT--CDACSPGH 1241
Query: 802 TGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCR 861
+G++C +P +S +PG C C P
Sbjct: 1242 SGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDP---------------------- 1279
Query: 862 NNSTCLALVDANQHCICREEFEGKNC 887
+ + DA C C+ + EG C
Sbjct: 1280 -QGSVSSQCDAAGQCQCKAQVEGLTC 1304
Score = 37.0 bits (84), Expect = 0.31
Identities = 33/126 (26%), Positives = 48/126 (38%), Gaps = 35/126 (27%)
Query: 1103 CICPRGYTGAYCEKSIDNCAEPELNSVICLNGGIC--VDGPGHTFDC--------RCLPG 1152
C CP GY G C+ +CA + L G C + GH+ C +C
Sbjct: 1530 CRCPPGYIGLSCQ----DCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHN 1585
Query: 1153 FSGQFCEI------------NINECSSSPC-------LHGADCED-HINGYVCK-CQPGW 1191
+G+FCE+ +C C + CE GY C C+PG+
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 1192 SGHHCE 1197
+G +CE
Sbjct: 1646 TGQYCE 1651
Score = 36.6 bits (83), Expect = 0.40
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 6/83 (7%)
Query: 1151 PGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGH----HCENELE-CIPN 1205
PG S + + + EC P G C+D GY + GH C + C P
Sbjct: 1516 PGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPE 1575
Query: 1206 SCVHELCMENEPGSTC-LCTPGF 1227
+ C N G C LC PG+
Sbjct: 1576 TGACSQCQHNAAGEFCELCAPGY 1598
Score = 35.4 bits (80), Expect = 0.90
Identities = 34/150 (22%), Positives = 49/150 (32%), Gaps = 42/150 (28%)
Query: 1103 CICPRGYTGAYCEKS------------IDNCAEPELNSVICLNGGICVDGPGHTFDC--- 1147
C CP GY+G CE + C+ N + C GH +C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNG----HASSCDPVYGHCLNCQHN 786
Query: 1148 -------RCLPGFSGQFCEININECSSSPCLH-------GADCEDHINGYVC--KCQPGW 1191
+C GF G + C PC + C +G C PG+
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 1192 SGHHCENELECIPNSCVHELCMENEPGSTC 1221
+G CE+ C P + + +PG C
Sbjct: 847 TGRRCES---CAPGYEGNPI----QPGGKC 869
Score = 34.7 bits (78), Expect = 1.5
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 374 CESFPLRNNATCKKC-EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRF 432
CE P ++ ATC E ++ C C GF CE + C+L CL+ C
Sbjct: 4108 CERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLRE-PCLHGGTCQGT---- 4162
Query: 433 KYVCIPGCTKNPC 445
+ +C+PG + C
Sbjct: 4163 RCLCLPGFSGPRC 4175
Score = 34.3 bits (77), Expect = 2.0
Identities = 45/171 (26%), Positives = 57/171 (33%), Gaps = 35/171 (20%)
Query: 1078 IKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI----DNCAEPELNSVICLN 1133
+++ C+ P CQ G+T P G CE+ EPE
Sbjct: 1121 LEVEQCSCPPGYRGPSCQDCDTGYTRT-PSGLYLGTCERCSCHGHSEACEPET------- 1172
Query: 1134 GGICVDGPGHTFDCRC---LPGFSGQFCEININECSSSPCLHGA-------DCEDHINGY 1183
G C HT RC PG+ G +C PC C +G+
Sbjct: 1173 -GACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGH 1231
Query: 1184 -VCK-CQPGWSGHHCENELECIP----NSCVHELCMENE--PGST-CLCTP 1225
C C PG SG HCE C P N + C + PG C C P
Sbjct: 1232 PTCDACSPGHSGRHCE---RCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDP 1279
Score = 34.3 bits (77), Expect = 2.0
Identities = 27/123 (21%), Positives = 44/123 (35%), Gaps = 31/123 (25%)
Query: 200 CHCQPPFSGKYCQE-------------LDACSFKPCKNN--------GSCINKRENWDEQ 238
C C P + G CQ+ L C C + G+C + N +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGE 1589
Query: 239 AYECVCHPPFTGKNCSEIIGQCQPHVC--------FHGNCSNITSNSFIC-ECDEQFSGP 289
E +C P + G + CQP C F C ++ + + C C+ ++G
Sbjct: 1590 FCE-LCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQ 1648
Query: 290 FCE 292
+CE
Sbjct: 1649 YCE 1651
Score = 33.9 bits (76), Expect = 2.6
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 3/71 (4%)
Query: 859 PCRNNSTCLALVDANQHCICREEFEGKNCE-IDVKDCLFLSCQDYGDCEDMVN--NFRCI 915
PC+N C ++ C+C F G CE C +C C + + + C
Sbjct: 3852 PCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCR 3911
Query: 916 CRPGFSGSLCE 926
C G SG CE
Sbjct: 3912 CHLGRSGLRCE 3922
Score = 32.3 bits (72), Expect = 7.6
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
Query: 260 CQPHVCFHGN-CSNITSNSFICECDEQFSGPFCEVS-AKPCVSLLFWKRGICPN--SSSA 315
C+ C +G C + S+S++C C F+G CE S A C C N
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRG 3907
Query: 316 YTYECPKGSSSQNGETDVS 334
YT C G S E V+
Sbjct: 3908 YTCRCHLGRSGLRCEEGVT 3926
Score = 32.0 bits (71), Expect = 9.9
Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 20/117 (17%)
Query: 2592 GLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC------ 2645
GL + P R+ + C L +C T C G FC
Sbjct: 1538 GLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPG 1597
Query: 2646 ------TETVSTCD----PEHDPPHHCSRGATCISL-PHGYTC-FCPLGTTGIYCEQ 2690
T C P +P + SR TC SL GY C C G TG YCEQ
Sbjct: 1598 YYGDATAGTPEDCQPCACPLTNPENMFSR--TCESLGAGGYRCTACEPGYTGQYCEQ 1652
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 227 bits (579), Expect = 1e-58
Identities = 129/374 (34%), Positives = 180/374 (48%), Gaps = 53/374 (14%)
Query: 781 KNNSTCTDLYKSYRCECTSGWTGQNCSEEINE--------------------------CD 814
+ ST T L SYR C+ + G NCS + C
Sbjct: 159 EQTSTLTRLRYSYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQ 218
Query: 815 SDPCMNGGLCHES----TIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALV 870
C++G CHE + P + CLC P + G+ C N C + HN CR + TC
Sbjct: 219 QPICLSG--CHEQNGYCSKPAE--CLCRPGWQGRLC----NEC-IPHNGCR-HGTC---- 264
Query: 871 DANQHCICREEFEGKNCEIDVKDCLFLS-CQDYGDCEDM-VNNFRCICRPGFSGSLCEIE 928
C C E + G C+ D+ C S C++ C + ++ C CRPG++G CE+E
Sbjct: 265 STPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELE 324
Query: 929 INECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG- 987
++EC S PC+N G+C D + + C C P Y+G CE C SPC + +C R G
Sbjct: 325 LSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGA 384
Query: 988 -YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDC 1046
Y C C P +TG NCE +D C S PC + G C++ C C+ GF GT+CE + +DC
Sbjct: 385 NYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDC 444
Query: 1047 LSNPCLH-GRCTELINEYPCSCDADGTSTQCKIK--INDCTSIPCMNEGFC--QKSAHGF 1101
NPC H G C +L N C+C A + +C+++ I+ C S PC N C S F
Sbjct: 445 ARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTF 504
Query: 1102 TCICPRGYTGAYCE 1115
C CP G+ G+ CE
Sbjct: 505 VCNCPYGFVGSRCE 518
Score = 210 bits (535), Expect = 2e-53
Identities = 106/336 (31%), Positives = 160/336 (47%), Gaps = 22/336 (6%)
Query: 759 CLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC 818
CL W G +C+Q C + N C+ K C C GW G+ C+E C
Sbjct: 208 CLPGWTGEYCQQPI--CLSGCHEQNGYCS---KPAECLCRPGWQGRLCNE---------C 253
Query: 819 MNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCIC 878
+ C T + C C + G FC Q N C H+PC+N +TC + C C
Sbjct: 254 IPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTH-HSPCKNGATCSNSGQRSYTCTC 312
Query: 879 REEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCK 938
R + G +CE+++ +C C++ G C+D + + C+C PG+ G CE C+ PC
Sbjct: 313 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 372
Query: 939 NNGTCVDLTN--RFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY 996
N G+C + + C C P + G CE V++C +PC + C+ R C C PG+
Sbjct: 373 NGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF 432
Query: 997 TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCE--TNANDCLSNPCLH- 1053
TG CE+++ +C PC H G C D N C C +GF G CE T+ + C S+PC +
Sbjct: 433 TGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNR 492
Query: 1054 GRC-TELINE-YPCSCDADGTSTQCKIKINDCTSIP 1087
C T+L + + C+C ++C+ + S P
Sbjct: 493 ATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPPSFP 528
Score = 209 bits (533), Expect = 3e-53
Identities = 113/317 (35%), Positives = 153/317 (48%), Gaps = 21/317 (6%)
Query: 669 CVPGFKGTQCEIDIDECASHP----CKNGATCIDQPG--NYFC-QCVPPFKVVDG----- 716
C+PG+ G C+ I H C A C+ +PG C +C+P G
Sbjct: 208 CLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTP 267
Query: 717 FSCLCNPGYVGIRCEQDIDDCILNA-CEHNSTCKDL-HLSYQCVCLSDWEGNFCEQESNE 774
+ C C+ G+ G+ C+QD++ C ++ C++ +TC + SY C C + G CE E +E
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE 327
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
C NPC+N +C D Y C C G+ G +C C PC NGG C E +
Sbjct: 328 CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYA 387
Query: 835 CLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC 894
C CPP +TG C ++ + C NPC N CL ++ C CR F G CE+ V DC
Sbjct: 388 CECPPNFTGSNCEKKVDRC--TSNPCANGGQCLNR-GPSRMCRCRPGFTGTYCELHVSDC 444
Query: 895 LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEI--EINECSSEPCKNNGTC-VDL-TNRF 950
C G C D+ N C C GFSG CE+ I+ C+S PC N TC DL T+ F
Sbjct: 445 ARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTF 504
Query: 951 FCNCEPEYHGPFCELDV 967
CNC + G CE V
Sbjct: 505 VCNCPYGFVGSRCEFPV 521
Score = 192 bits (487), Expect = 6e-48
Identities = 116/372 (31%), Positives = 167/372 (44%), Gaps = 45/372 (12%)
Query: 877 ICREEFEGKNCEIDVKDCL----FLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINEC 932
IC + + G NC K CQ G+ C PG++G C+ I C
Sbjct: 174 ICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLS---------CLPGWTGEYCQQPI--C 222
Query: 933 SSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG--YNC 990
S + NG C C C P + G C + C+ C + T + C
Sbjct: 223 LSGCHEQNGYCSKPAE---CLCRPGWQGRLC---------NECIPHNGCRHGTCSTPWQC 270
Query: 991 LCAPGYTGINCEINLDECLSE-PCLHDGVCID-GINHYTCDCKSGFFGTHCETNANDCLS 1048
C G+ G+ C+ +L+ C PC + C + G YTC C+ G+ G CE ++C S
Sbjct: 271 TCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDS 330
Query: 1049 NPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHG--FTCIC 1105
NPC +G C + + Y C C C+ C PC N G C++ G + C C
Sbjct: 331 NPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 390
Query: 1106 PRGYTGAYCEKSIDNCAEPELNSVICLNGGICVD-GPGHTFDCRCLPGFSGQFCEININE 1164
P +TG+ CEK +D C S C NGG C++ GP CRC PGF+G +CE+++++
Sbjct: 391 PPNFTGSNCEKKVDRCT-----SNPCANGGQCLNRGPSRM--CRCRPGFTGTYCELHVSD 443
Query: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCT 1224
C+ +PC HG C D NG +C C G+SG C E+ ++C C T L T
Sbjct: 444 CARNPCAHGGTCHDLENGLMCTCPAGFSGRRC--EVRTSIDACASSPCFNRATCYTDLST 501
Query: 1225 PGFM-TCSIGLL 1235
F+ C G +
Sbjct: 502 DTFVCNCPYGFV 513
Score = 137 bits (345), Expect = 2e-31
Identities = 76/260 (29%), Positives = 111/260 (42%), Gaps = 12/260 (4%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDACSF-KPCKNNGSCINKRENWDEQAY 240
C H C S + C C + G +C Q+L+ C+ PCKN +C N +++Y
Sbjct: 253 CIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNS----GQRSY 308
Query: 241 ECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVS 300
C C P +TG +C + +C + C +G + + C C + G CE S C
Sbjct: 309 TCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCAD 368
Query: 301 LLFWKRGICP--NSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCIC 358
+ G C N + Y ECP + N E V + PC NG C+ MC C
Sbjct: 369 SPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRC 428
Query: 359 SPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE--KAIDHCKLLS 416
P FT C+ + C P + TC E C+C +GF+ + CE +ID C S
Sbjct: 429 RPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDAC--AS 486
Query: 417 INCLNEEWCFNIIGRFKYVC 436
C N C+ + +VC
Sbjct: 487 SPCFNRATCYTDLSTDTFVC 506
Score = 125 bits (313), Expect = 9e-28
Identities = 86/284 (30%), Positives = 121/284 (42%), Gaps = 37/284 (13%)
Query: 202 CQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQ 261
C P ++G+YCQ+ C + NG C + EC+C P + G+ C+E C
Sbjct: 208 CLPGWTGEYCQQ-PICLSGCHEQNGYC--------SKPAECLCRPGWQGRLCNE----CI 254
Query: 262 PHV-CFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRG-ICPNSSS-AYTY 318
PH C HG CS + C CDE + G FC+ C K G C NS +YT
Sbjct: 255 PHNGCRHGTCST----PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTC 310
Query: 319 ECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFP 378
C G + + E ++SE PC+NG C + C+C P + L C+ SC P
Sbjct: 311 TCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP 370
Query: 379 LRNNATCKKCEK--DYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFN--------- 427
N +C++ + +Y C C FT NCEK +D C S C N C N
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC--TSNPCANGGQCLNRGPSRMCRC 428
Query: 428 ---IIGRFKYVCIPGCTKNPCWFLKNVYLIHQHL-CYCGVTFHG 467
G + + + C +NPC + + L C C F G
Sbjct: 429 RPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSG 472
Score = 115 bits (289), Expect = 5e-25
Identities = 78/269 (28%), Positives = 113/269 (42%), Gaps = 44/269 (16%)
Query: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCD------CKSGFFGTHCET 1041
Y +C+ Y G NC S C D HY C C G+ G +C+
Sbjct: 171 YRVICSDNYYGDNC--------SRLCKKRN---DHFGHYVCQPDGNLSCLPGWTGEYCQQ 219
Query: 1042 NANDCLSNPC--LHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAH 1099
CLS C +G C++ C C C N+C G C
Sbjct: 220 PI--CLSG-CHEQNGYCSKPAE---CLCRPGWQGRLC----NECIPHNGCRHGTCSTP-- 267
Query: 1100 GFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCE 1159
+ C C G+ G +C++ ++ C C NG C + ++ C C PG++G CE
Sbjct: 268 -WQCTCDEGWGGLFCDQDLNYCTHHSP----CKNGATCSNSGQRSYTCTCRPGYTGVDCE 322
Query: 1160 ININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENE-LECIPNSCVH-ELCMENEP 1217
+ ++EC S+PC +G C+D +GY C C PG+ G HCE+ L C + C + C E
Sbjct: 323 LELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQ 382
Query: 1218 GS--TCLCTPGFMTCSIGLLCGDEIRRIT 1244
G+ C C P F G C ++ R T
Sbjct: 383 GANYACECPPNF----TGSNCEKKVDRCT 407
Score = 98.2 bits (243), Expect = 1e-19
Identities = 67/241 (27%), Positives = 100/241 (41%), Gaps = 22/241 (9%)
Query: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
C NG +C S + Y C + G ++ N C++ CKD+ + C C
Sbjct: 294 CKNGATC-SNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP 352
Query: 595 SYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCN--CSGLQRYERNICEIDTEDCKSASC 652
Y G C + C + + G C + N C + + CE + C S C
Sbjct: 353 GYYGLHCEHSTLSCADSPCFN-GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPC 411
Query: 653 KNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFK 712
NG + +C PGF GT CE+ + +CA +PC +G TC D
Sbjct: 412 ANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHD-------------- 457
Query: 713 VVDGFSCLCNPGYVGIRCE--QDIDDCILNACEHNSTC-KDLHL-SYQCVCLSDWEGNFC 768
+ +G C C G+ G RCE ID C + C + +TC DL ++ C C + G+ C
Sbjct: 458 LENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Query: 769 E 769
E
Sbjct: 518 E 518
Score = 68.2 bits (165), Expect = 1e-10
Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 14/103 (13%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
N + V +C ++PC+ NGG C+ G S C C G+ G++C VS C +
Sbjct: 398 NCEKKVDRCTSNPCA-----NGGQCLNRGPSRMCRCRPGFTGTYCELHVSDC-----ARN 447
Query: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCEQALSI----SDPSF 2699
C+ G TC L +G C CP G +G CE SI S P F
Sbjct: 448 PCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCF 490
Score = 65.5 bits (158), Expect = 8e-10
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 12/119 (10%)
Query: 179 SSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDE 237
+S C+ G+CL+ S+ C C+P F+G YC+ + C+ PC + G+C + E
Sbjct: 407 TSNPCANGGQCLNRGPSRM--CRCRPGFTGTYCELHVSDCARNPCAHGGTCHDL-----E 459
Query: 238 QAYECVCHPPFTGKNCS--EIIGQCQPHVCFH-GNC-SNITSNSFICECDEQFSGPFCE 292
C C F+G+ C I C CF+ C +++++++F+C C F G CE
Sbjct: 460 NGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 64.7 bits (156), Expect = 1e-09
Identities = 32/78 (41%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 2335 HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ----FASCENNPCGNGATCVPKS 2390
HV CA + C + GTC L C CP +SG+ C+ +C ++PC N ATC
Sbjct: 440 HVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDL 499
Query: 2391 GTD-IVCLCPYGRSGPLC 2407
TD VC CPYG G C
Sbjct: 500 STDTFVCNCPYGFVGSRC 517
Score = 61.6 bits (148), Expect = 1e-08
Identities = 31/76 (40%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C N C NGG+C G + CRC P + G C VS C N C H C D C
Sbjct: 406 CTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC-HDLENGLMC 464
Query: 2938 LCTLGWVGRYCENKTS 2953
C G+ GR CE +TS
Sbjct: 465 TCPAGFSGRRCEVRTS 480
Score = 59.7 bits (143), Expect = 4e-08
Identities = 34/89 (38%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 2610 HASPCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC 2668
H SPC NG TC SG Y C C G+ G C +S CD + C G +C
Sbjct: 290 HHSPCK-----NGATCSNSGQRSYTCTCRPGYTGVDCELELSECDS-----NPCRNGGSC 339
Query: 2669 ISLPHGYTCFCPLGTTGIYCEQA-LSISD 2696
GY C CP G G++CE + LS +D
Sbjct: 340 KDQEDGYHCLCPPGYYGLHCEHSTLSCAD 368
Score = 54.7 bits (130), Expect = 1e-06
Identities = 32/75 (42%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCI-SLPHGYTCFCPL 2681
GTC T C C GW G FC + ++ C H P C GATC S YTC C
Sbjct: 262 GTC---STPWQCTCDEGWGGLFCDQDLNYC-THHSP---CKNGATCSNSGQRSYTCTCRP 314
Query: 2682 GTTGIYCEQALSISD 2696
G TG+ CE LS D
Sbjct: 315 GYTGVDCELELSECD 329
Score = 53.9 bits (128), Expect = 2e-06
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKS-GTDIV 2395
C + CRN G+C + C CP Y G C+ + SC ++PC NG +C ++ G +
Sbjct: 328 CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYA 387
Query: 2396 CLCPYGRSGPLCTDAIN 2412
C CP +G C ++
Sbjct: 388 CECPPNFTGSNCEKKVD 404
Score = 53.9 bits (128), Expect = 2e-06
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGAT 2385
G N E V C + C N G C++ + C C ++G C+ + C NPC +G T
Sbjct: 396 GSNCEK-KVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGT 454
Query: 2386 CVPKSGTDIVCLCPYGRSGPLC 2407
C ++C CP G SG C
Sbjct: 455 CHDLE-NGLMCTCPAGFSGRRC 475
Score = 53.5 bits (127), Expect = 3e-06
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS-VSCLNNLCLHQSLCIP-DQSFSYS 2936
C N CRNGG C + C C P + G C S +SC ++ C + C +Q +Y+
Sbjct: 328 CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYA 387
Query: 2937 CLCTLGWVGRYCENKTSFSTAKFMGN 2962
C C + G CE K T+ N
Sbjct: 388 CECPPNFTGSNCEKKVDRCTSNPCAN 413
Score = 51.2 bits (121), Expect = 2e-05
Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 2338 WCAHHL-CRNNGTCISDNENLF-CECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTD 2393
+C HH C+N TC + + + C C Y+G C+ + C++NPC NG +C +
Sbjct: 287 YCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQE-DG 345
Query: 2394 IVCLCPYGRSGPLC 2407
CLCP G G C
Sbjct: 346 YHCLCPPGYYGLHC 359
Score = 49.7 bits (117), Expect = 5e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
+ H S C+ C +GGTC + + C C G+ G C E ++ D P C AT
Sbjct: 438 ELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC-EVRTSIDACASSP--CFNRAT 494
Query: 2668 CIS--LPHGYTCFCPLGTTGIYCEQALSISDPSF 2699
C + + C CP G G CE + + PSF
Sbjct: 495 CYTDLSTDTFVCNCPYGFVGSRCEFPVGL-PPSF 527
Score = 49.3 bits (116), Expect = 6e-05
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
S C C NGG+C + +C C G+ G C + +C D P C G +C
Sbjct: 326 SECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSC---ADSP--CFNGGSCRER 380
Query: 2672 PHG--YTCFCPLGTTGIYCEQ 2690
G Y C CP TG CE+
Sbjct: 381 NQGANYACECPPNFTGSNCEK 401
Score = 45.1 bits (105), Expect = 0.001
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS---CLNNLCLHQSLCIPDQSF-S 2934
C N C +GG C C C ++G C S C ++ C +++ C D S +
Sbjct: 444 CARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDT 503
Query: 2935 YSCLCTLGWVGRYCE 2949
+ C C G+VG CE
Sbjct: 504 FVCNCPYGFVGSRCE 518
Score = 42.4 bits (98), Expect = 0.007
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 7/58 (12%)
Query: 2899 CRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFST 2956
C C P W G CN+ + +N C H + P + C C GW G +C+ ++ T
Sbjct: 239 CLCRPGWQGRLCNECIP--HNGCRHGTCSTP-----WQCTCDEGWGGLFCDQDLNYCT 289
Score = 40.8 bits (94), Expect = 0.021
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 14/79 (17%)
Query: 2881 YNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQS------LCIPDQSFS 2934
+N CR+G C+ T + C C W G C+Q + N C H S C S
Sbjct: 256 HNGCRHG-TCS---TPWQCTCDEGWGGLFCDQDL----NYCTHHSPCKNGATCSNSGQRS 307
Query: 2935 YSCLCTLGWVGRYCENKTS 2953
Y+C C G+ G CE + S
Sbjct: 308 YTCTCRPGYTGVDCELELS 326
Score = 39.3 bits (90), Expect = 0.062
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 10/69 (14%)
Query: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK----DAGLFFPSFN-GNSY 2155
S C ++ C +GGTCH L +G++ C CP F+GR CE DA P FN Y
Sbjct: 442 SDCARNPCAHGGTCHD--LENGLM---CTCPAGFSGRRCEVRTSIDACASSPCFNRATCY 496
Query: 2156 LELPFLKFV 2164
+L FV
Sbjct: 497 TDLSTDTFV 505
Score = 38.5 bits (88), Expect = 0.11
Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 5/48 (10%)
Query: 2901 CLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
CLP W G C Q + CL+ C S CLC GW GR C
Sbjct: 208 CLPGWTGEYCQQPI-CLSGCHEQNGYC----SKPAECLCRPGWQGRLC 250
Score = 36.2 bits (82), Expect = 0.53
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 5/56 (8%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK--DAGLFFPSFNGNSYL 2156
C C NGG+C + ++ C+CP +FTG CEK D P NG L
Sbjct: 366 CADSPCFNGGSCRE---RNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCL 418
Score = 35.8 bits (81), Expect = 0.69
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 7/70 (10%)
Query: 2341 HHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASC-ENNPCGNGATCVPKSGTDIVCL 2397
H+ CR+ GTC + + C C + G C C ++PC NGATC C
Sbjct: 256 HNGCRH-GTCSTPWQ---CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCT 311
Query: 2398 CPYGRSGPLC 2407
C G +G C
Sbjct: 312 CRPGYTGVDC 321
Score = 32.7 bits (73), Expect = 5.8
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSF 2150
C C N TC+ + +F C+CP F G CE GL PSF
Sbjct: 484 CASSPCFNRATCYTDLSTD---TFVCNCPYGFVGSRCEFPVGL-PPSF 527
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 222 bits (565), Expect = 5e-57
Identities = 116/332 (34%), Positives = 168/332 (50%), Gaps = 22/332 (6%)
Query: 877 ICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEP 936
+C ++G C + CL + +G C+ C CR G+ G C+ EC P
Sbjct: 211 VCNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYCD----ECIRYP 261
Query: 937 CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKI-SPCLDEENCVYRTDG-YNCLCAP 994
+GTC + CNC+ + G FC D+N C PC + C G Y C C P
Sbjct: 262 GCLHGTC---QQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP 318
Query: 995 GYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG 1054
GYTG CE+ +DEC PC + G C D N Y+C C GF+G CE +A C PC +G
Sbjct: 319 GYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNG 378
Query: 1055 -RCTELINE-YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGA 1112
RC++ + Y C C + C+ KI+ C+S PC N C + C C G++G
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGR 438
Query: 1113 YCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLH 1172
+C+ ++D+CA S C NGG C DG + F C C PG++G+ C ++ C +PC +
Sbjct: 439 HCDDNVDDCA-----SSPCANGGTCRDGV-NDFSCTCPPGYTGRNCSAPVSRCEHAPCHN 492
Query: 1173 GADCEDHINGYVCKCQPGWSGHHCENELECIP 1204
GA C + + YVC+C G+ G +C+ L +P
Sbjct: 493 GATCHERGHRYVCECARGYGGPNCQFLLPELP 524
Score = 218 bits (556), Expect = 6e-56
Identities = 126/351 (35%), Positives = 163/351 (46%), Gaps = 34/351 (9%)
Query: 669 CVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGI 728
C PG+KG C I C G C +Q G FC C C G+ G
Sbjct: 212 CNPGWKGPYCTEPI-------CLPG--CDEQHG--FCD--------KPGECKCRVGWQGR 252
Query: 729 RCEQDIDDCI-LNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMN-PCKNNSTC 786
C D+CI C H TC+ +QC C W G FC Q+ N C + PCKN +TC
Sbjct: 253 YC----DECIRYPGCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATC 304
Query: 787 TDLYK-SYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQF 845
T+ + SY C C G+TG C I+ECD PC NGG C + + + C CPP + G+
Sbjct: 305 TNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTD--LENSYSCTCPPGFYGKI 362
Query: 846 CHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDC 905
C C PC N C D C C + G NCE + C C + C
Sbjct: 363 CELSAMTC--ADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC 420
Query: 906 EDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCEL 965
D+ + + C C+ GFSG C+ +++C+S PC N GTC D N F C C P Y G C
Sbjct: 421 VDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA 480
Query: 966 DVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHD 1016
V++C+ +PC + C R Y C CA GY G NC+ L E P + D
Sbjct: 481 PVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVD 531
Score = 218 bits (555), Expect = 7e-56
Identities = 125/404 (30%), Positives = 183/404 (45%), Gaps = 52/404 (12%)
Query: 782 NNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVC------ 835
++S TDL SYR C + G+ CS D G F C
Sbjct: 164 HSSGRTDLKYSYRFVCDEHYYGEGCSVFCRPRDD-------------AFGHFTCGERGEK 210
Query: 836 LCPPLYTGQFCHQRYNL--CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE--IDV 891
+C P + G +C + L CD H C D C CR ++G+ C+ I
Sbjct: 211 VCNPGWKGPYCTEPICLPGCDEQHGFC----------DKPGECKCRVGWQGRYCDECIRY 260
Query: 892 KDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSS-EPCKNNGTCVDL-TNR 949
CL +CQ ++C C+ G+ G C ++N C+ +PCKN TC +
Sbjct: 261 PGCLHGTCQQ---------PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGS 311
Query: 950 FFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECL 1009
+ C+C P Y G CEL +++C SPC + +C + Y+C C PG+ G CE++ C
Sbjct: 312 YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCA 371
Query: 1010 SEPCLHDGVCIDGINH-YTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYPCSC 1067
PC + G C D + Y+C C G+ G +CE + C S+PC +G +C +L + Y C C
Sbjct: 372 DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRC 431
Query: 1068 DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELN 1127
A + C ++DC S PC N G C+ + F+C CP GYTG C + C
Sbjct: 432 QAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAP-- 489
Query: 1128 SVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCL 1171
C NG C + GH + C C G+ G C+ + E P +
Sbjct: 490 ---CHNGATCHER-GHRYVCECARGYGGPNCQFLLPELPPGPAV 529
Score = 213 bits (543), Expect = 2e-54
Identities = 112/342 (32%), Positives = 164/342 (47%), Gaps = 24/342 (7%)
Query: 707 CVPPFKVVDGFSC------LCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCL 760
C P F+C +CNPG+ G C + I C+ E + C +C C
Sbjct: 192 CRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPI--CLPGCDEQHGFCDK---PGECKCR 246
Query: 761 SDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD-PCM 819
W+G +C+ EC P + TC + ++C C GW G C++++N C PC
Sbjct: 247 VGWQGRYCD----ECIRYPGCLHGTCQ---QPWQCNCQEGWGGLFCNQDLNYCTHHKPCK 299
Query: 820 NGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICR 879
NG C +T G + C C P YTG C + CD +PC+N +C L + + C C
Sbjct: 300 NGATC-TNTGQGSYTCSCRPGYTGATCELGIDECD--PSPCKNGGSCTDL-ENSYSCTCP 355
Query: 880 EEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNN-FRCICRPGFSGSLCEIEINECSSEPCK 938
F GK CE+ C C + G C D + + C C G+SG CE +I+ CSS PC
Sbjct: 356 PGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCS 415
Query: 939 NNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTG 998
N CVDL + + C C+ + G C+ +V+ C SPC + C + ++C C PGYTG
Sbjct: 416 NGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTG 475
Query: 999 INCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
NC + C PC + C + + Y C+C G+ G +C+
Sbjct: 476 RNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
Score = 212 bits (539), Expect = 5e-54
Identities = 105/334 (31%), Positives = 155/334 (46%), Gaps = 17/334 (5%)
Query: 758 VCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP 817
VC W+G +C + C + + C K C+C GW G+ C E
Sbjct: 211 VCNPGWKGPYCTEPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYCDE--------- 256
Query: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCI 877
C+ C T + C C + G FC+Q N C H PC+N +TC + C
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTH-HKPCKNGATCTNTGQGSYTCS 315
Query: 878 CREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
CR + G CE+ + +C C++ G C D+ N++ C C PGF G +CE+ C+ PC
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 938 KNNGTCVDLTNR-FFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY 996
N G C D + + C C Y G CE ++ C SPC + CV D Y C C G+
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGF 435
Query: 997 TGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-R 1055
+G +C+ N+D+C S PC + G C DG+N ++C C G+ G +C + C PC +G
Sbjct: 436 SGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGAT 495
Query: 1056 CTELINEYPCSCDADGTSTQCKIKINDCTSIPCM 1089
C E + Y C C C+ + + P +
Sbjct: 496 CHERGHRYVCECARGYGGPNCQFLLPELPPGPAV 529
Score = 198 bits (503), Expect = 8e-50
Identities = 115/365 (31%), Positives = 170/365 (46%), Gaps = 45/365 (12%)
Query: 877 ICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRC------ICRPGFSGSLCEIEIN 930
+C E + G+ C + F +D D +F C +C PG+ G C I
Sbjct: 178 VCDEHYYGEGCSV------FCRPRD-----DAFGHFTCGERGEKVCNPGWKGPYCTEPI- 225
Query: 931 ECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRT--DGY 988
C + +G C D C C + G +C+ C+ C++ T +
Sbjct: 226 -CLPGCDEQHGFC-DKPGE--CKCRVGWQGRYCD---------ECIRYPGCLHGTCQQPW 272
Query: 989 NCLCAPGYTGINCEINLDECLS-EPCLHDGVCID-GINHYTCDCKSGFFGTHCETNANDC 1046
C C G+ G+ C +L+ C +PC + C + G YTC C+ G+ G CE ++C
Sbjct: 273 QCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDEC 332
Query: 1047 LSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHG-FTCI 1104
+PC +G CT+L N Y C+C C++ C PC N G C S G ++C
Sbjct: 333 DPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR 392
Query: 1105 CPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININE 1164
CP GY+G CEK ID C+ S C NG CVD G + CRC GFSG+ C+ N+++
Sbjct: 393 CPVGYSGFNCEKKIDYCS-----SSPCSNGAKCVD-LGDAYLCRCQAGFSGRHCDDNVDD 446
Query: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHE--LCMENEPGSTCL 1222
C+SSPC +G C D +N + C C PG++G +C + ++ H C E C
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCE 506
Query: 1223 CTPGF 1227
C G+
Sbjct: 507 CARGY 511
Score = 181 bits (460), Expect = 8e-45
Identities = 107/327 (32%), Positives = 157/327 (48%), Gaps = 29/327 (8%)
Query: 907 DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELD 966
D+ ++R +C + G C + + + TC + + C P + GP+C
Sbjct: 170 DLKYSYRFVCDEHYYGEGCSVFCRP--RDDAFGHFTCGERGEKV---CNPGWKGPYCTEP 224
Query: 967 VNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEP-CLHDGVCIDGINH 1025
+ P DE++ G C C G+ G C DEC+ P CLH G C
Sbjct: 225 I----CLPGCDEQHGFCDKPG-ECKCRVGWQGRYC----DECIRYPGCLH-GTCQQP--- 271
Query: 1026 YTCDCKSGFFGTHCETNANDCLSN-PCLHGR-CTEL-INEYPCSCDADGTSTQCKIKIND 1082
+ C+C+ G+ G C + N C + PC +G CT Y CSC T C++ I++
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDE 331
Query: 1083 CTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPG 1142
C PC N G C + ++C CP G+ G CE S CA+ C NGG C D P
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP-----CFNGGRCSDSPD 386
Query: 1143 HTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-E 1201
+ CRC G+SG CE I+ CSSSPC +GA C D + Y+C+CQ G+SG HC++ + +
Sbjct: 387 GGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDD 446
Query: 1202 CIPNSCVH-ELCMENEPGSTCLCTPGF 1227
C + C + C + +C C PG+
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGY 473
Score = 155 bits (391), Expect = 8e-37
Identities = 87/280 (31%), Positives = 123/280 (43%), Gaps = 15/280 (5%)
Query: 172 QFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDACSF-KPCKNNGSCI 229
++C E + C HG C + + C+CQ + G +C Q+L+ C+ KPCKN +C
Sbjct: 252 RYCDECIRYPGCL-HGTC-----QQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCT 305
Query: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
N + +Y C C P +TG C I +C P C +G NS+ C C F G
Sbjct: 306 NTGQG----SYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGK 361
Query: 290 FCEVSAKPCVSLLFWKRGICPNS-SSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCI 348
CE+SA C + G C +S Y+ CP G S N E + S PC NG C+
Sbjct: 362 ICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 349 KISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA 408
+ + +C C F+ C C S P N TC+ D+ C+C G+T +NC
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 409 IDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFL 448
+ C+ C N C R+ C G C FL
Sbjct: 482 VSRCE--HAPCHNGATCHERGHRYVCECARGYGGPNCQFL 519
Score = 108 bits (271), Expect = 6e-23
Identities = 85/349 (24%), Positives = 125/349 (35%), Gaps = 70/349 (20%)
Query: 435 VCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQ-------LGFAG 487
+C+PGC + HG C G + WQ + + G
Sbjct: 225 ICLPGCDEQ----------------------HGFCDKPGECKCRVGWQGRYCDECIRYPG 262
Query: 488 SEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDS 547
CQ NC E + +D N + H + C NG +C +
Sbjct: 263 CLHGTCQQPWQC------NCQEGWGGLFCNQDLN---YCTHH---KPCKNGATCTNTGQG 310
Query: 548 QEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDY 607
Y C + G + + C++ C D N C+C + G++C ++
Sbjct: 311 S-YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT 369
Query: 608 CL-------GNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTH 660
C G S S G ++C C Y CE + C S+ C NG
Sbjct: 370 CADGPCFNGGRCSDSPDG-----GYSCRCP--VGYSGFNCEKKIDYCSSSPCSNGAKCVD 422
Query: 661 LRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL 720
L + +C GF G C+ ++D+CAS PC NG TC D V+ FSC
Sbjct: 423 LGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDG--------------VNDFSCT 468
Query: 721 CNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCE 769
C PGY G C + C C + +TC + Y C C + G C+
Sbjct: 469 CPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
Score = 77.0 bits (188), Expect = 3e-13
Identities = 98/435 (22%), Positives = 142/435 (32%), Gaps = 113/435 (25%)
Query: 282 CDEQFSGPFCEVSAKP----CVSLLFWKRG--IC-PNSSSAYTYE--CPKGSSSQNGETD 332
CDE + G C V +P +RG +C P Y E C G Q+G D
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCD 238
Query: 333 VSEFSLVPCQNG------TDCIKISNDV--------MCICSPIFTDLLCKSIQTSCESF- 377
+ C+ G +CI+ + C C + L C C
Sbjct: 239 --KPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHK 296
Query: 378 PLRNNATCKKC-EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVC 436
P +N ATC + Y CSC G+T CE ID C C N C ++ + C
Sbjct: 297 PCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECD--PSPCKNGGSCTDLENSYSCTC 354
Query: 437 IPGCTKNPCWFLKNVYLIHQHLCYCGVTFH-GICQDKGPAQFEYVWQLGFAGSEGEKCQG 495
PG F + + C G F+ G C D + +G++G
Sbjct: 355 PPG-------FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG-------- 399
Query: 496 VIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCF 555
NC + Y + C+NG C+ D+ Y C
Sbjct: 400 ---------FNCEKKIDYCSSSP----------------CSNGAKCVDLGDA--YLCRCQ 432
Query: 556 LRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSIS 615
++G +N D + C + C+D +N C+C Y GR
Sbjct: 433 AGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR---------------- 476
Query: 616 VHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGY-FFRKCVPGFK 674
NCS C+ A C NG T H RG+ + +C G+
Sbjct: 477 ------------NCSA-----------PVSRCEHAPCHNGAT-CHERGHRYVCECARGYG 512
Query: 675 GTQCEIDIDECASHP 689
G C+ + E P
Sbjct: 513 GPNCQFLLPELPPGP 527
Score = 63.2 bits (152), Expect = 4e-09
Identities = 47/166 (28%), Positives = 61/166 (36%), Gaps = 36/166 (21%)
Query: 2554 GYSEYTPDLLPNGA---DFKN--------GFQGCIFTLQVRTEKDGHFRGLGNPEGHPNA 2602
G E P NG D +N GF G I L T DG G P+
Sbjct: 328 GIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDG 387
Query: 2603 GRS---------------VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTE 2647
G S + C +SPCS NG C++ G + C C G+ G C +
Sbjct: 388 GYSCRCPVGYSGFNCEKKIDYCSSSPCS-----NGAKCVDLGDAYLCRCQAGFSGRHCDD 442
Query: 2648 TVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
V C C+ G TC + ++C CP G TG C +S
Sbjct: 443 NVDDC-----ASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVS 483
Score = 61.2 bits (147), Expect = 2e-08
Identities = 45/139 (32%), Positives = 57/139 (41%), Gaps = 23/139 (16%)
Query: 2565 NGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGT 2624
NGA N QG +T R G LG + +C SPC NGG+
Sbjct: 300 NGATCTNTGQGS-YTCSCRPGYTGATCELG-----------IDECDPSPCK-----NGGS 342
Query: 2625 CIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHG-YTCFCPLGT 2683
C + S C C G+ G C + TC D P C G C P G Y+C CP+G
Sbjct: 343 CTDLENSYSCTCPPGFYGKICELSAMTCA---DGP--CFNGGRCSDSPDGGYSCRCPVGY 397
Query: 2684 TGIYCEQALSISDPSFRSN 2702
+G CE+ + S SN
Sbjct: 398 SGFNCEKKIDYCSSSPCSN 416
Score = 60.8 bits (146), Expect = 2e-08
Identities = 33/85 (38%), Positives = 40/85 (47%), Gaps = 10/85 (11%)
Query: 2605 SVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
+V C +SPC+ NGGTC + C C G+ G C+ VS C EH P C
Sbjct: 443 NVDDCASSPCA-----NGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRC--EHAP---CHN 492
Query: 2665 GATCISLPHGYTCFCPLGTTGIYCE 2689
GATC H Y C C G G C+
Sbjct: 493 GATCHERGHRYVCECARGYGGPNCQ 517
Score = 60.1 bits (144), Expect = 3e-08
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS-VSCLNNLCLHQSLCIPDQSFSYSC 2937
C + C+NGG CT ++SC C P + G C S ++C + C + C YSC
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 2938 LCTLGWVGRYCENKTSFSTAKFMGN 2962
C +G+ G CE K + ++ N
Sbjct: 392 RCPVGYSGFNCEKKIDYCSSSPCSN 416
Score = 59.7 bits (143), Expect = 4e-08
Identities = 30/71 (42%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
CA C N GTC + C CP Y+G+ C + CE+ PC NGATC + G VC
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATC-HERGHRYVC 505
Query: 2397 LCPYGRSGPLC 2407
C G GP C
Sbjct: 506 ECARGYGGPNC 516
Score = 58.9 bits (141), Expect = 8e-08
Identities = 37/97 (38%), Positives = 44/97 (45%), Gaps = 13/97 (13%)
Query: 2603 GRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHC 2662
GR +C P L GTC + CNC GW G FC + ++ C H P C
Sbjct: 251 GRYCDECIRYPGCLH-----GTCQQPWQ---CNCQEGWGGLFCNQDLNYC-THHKP---C 298
Query: 2663 SRGATCISLPHG-YTCFCPLGTTGIYCEQALSISDPS 2698
GATC + G YTC C G TG CE + DPS
Sbjct: 299 KNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPS 335
Score = 54.7 bits (130), Expect = 1e-06
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDIVC 2396
C C+N G+C + C CP + GK+C+ + +C + PC NG C C
Sbjct: 332 CDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 2397 LCPYGRSGPLCTDAIN 2412
CP G SG C I+
Sbjct: 392 RCPVGYSGFNCEKKID 407
Score = 52.8 bits (125), Expect = 5e-06
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 7/85 (8%)
Query: 2333 NCH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVP 2388
NC + +C+ C N C+ + C C +SG+ C C ++PC NG TC
Sbjct: 401 NCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTC-- 458
Query: 2389 KSG-TDIVCLCPYGRSGPLCTDAIN 2412
+ G D C CP G +G C+ ++
Sbjct: 459 RDGVNDFSCTCPPGYTGRNCSAPVS 483
Score = 50.8 bits (120), Expect = 2e-05
Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 2/78 (2%)
Query: 2874 CDGTA--CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQ 2931
CD C + C NGG C FSC C P + G C+ VS + H ++
Sbjct: 440 CDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHER 499
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
Y C C G+ G C+
Sbjct: 500 GHRYVCECARGYGGPNCQ 517
Score = 50.4 bits (119), Expect = 3e-05
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 2881 YNTCRNGGECTVNGT-TFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCL 2938
+ C+NG CT G +++C C P + G TC + C + C + C D SYSC
Sbjct: 295 HKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSC-TDLENSYSCT 353
Query: 2939 CTLGWVGRYCE 2949
C G+ G+ CE
Sbjct: 354 CPPGFYGKICE 364
Score = 50.4 bits (119), Expect = 3e-05
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
C + C NG +C G + CRC ++G C+ +V C ++ C + C D +SC
Sbjct: 409 CSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTC-RDGVNDFSC 467
Query: 2938 LCTLGWVGRYCENKTS 2953
C G+ GR C S
Sbjct: 468 TCPPGYTGRNCSAPVS 483
Score = 48.1 bits (113), Expect = 1e-04
Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2879 CGYNTCRNGGECTVNGTT-FSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYS 2936
C C NGG C+ + +SCRC ++G C + + C ++ C + + C+ D +Y
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV-DLGDAYL 428
Query: 2937 CLCTLGWVGRYCEN 2950
C C G+ GR+C++
Sbjct: 429 CRCQAGFSGRHCDD 442
Score = 46.6 bits (109), Expect = 4e-04
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 41/139 (29%)
Query: 159 CPLGLR-LNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDA 216
CP+G N K +C SS CS KC+ Y C CQ FSG++C + +D
Sbjct: 393 CPVGYSGFNCEKKIDYC----SSSPCSNGAKCVD--LGDAYLCRCQAGFSGRHCDDNVDD 446
Query: 217 CSFKPCKNNGSCINKRENWD-------------------EQA--------------YECV 243
C+ PC N G+C + ++ E A Y C
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCE 506
Query: 244 CHPPFTGKNCSEIIGQCQP 262
C + G NC ++ + P
Sbjct: 507 CARGYGGPNCQFLLPELPP 525
Score = 43.5 bits (101), Expect = 0.003
Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 24/91 (26%)
Query: 2624 TCIESGTSVYCNCTTGWKGSFCTETVST--CDPEH---DPPHHCSRGA--------TCIS 2670
TC E G V C GWKG +CTE + CD +H D P C CI
Sbjct: 203 TCGERGEKV---CNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIR 259
Query: 2671 LP---HG-----YTCFCPLGTTGIYCEQALS 2693
P HG + C C G G++C Q L+
Sbjct: 260 YPGCLHGTCQQPWQCNCQEGWGGLFCNQDLN 290
Score = 39.7 bits (91), Expect = 0.048
Identities = 20/49 (40%), Positives = 20/49 (40%), Gaps = 2/49 (4%)
Query: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP 2379
NC P C H C N TC CEC R Y G CQF E P
Sbjct: 477 NCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPP 525
Score = 38.9 bits (89), Expect = 0.081
Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 11/73 (15%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNL-CLHQSLCIPDQSFSYS 2936
C + TC+ + C C W G CNQ ++ C ++ C + + C SY+
Sbjct: 263 CLHGTCQQ---------PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYT 313
Query: 2937 CLCTLGWVGRYCE 2949
C C G+ G CE
Sbjct: 314 CSCRPGYTGATCE 326
Score = 37.4 bits (85), Expect = 0.24
Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 13/93 (13%)
Query: 2328 GKNIENC-HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENN-PCGNG 2383
G+ + C P C H GTC + C C + G C C ++ PC NG
Sbjct: 251 GRYCDECIRYPGCLH------GTC---QQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
ATC C C G +G C I+ P
Sbjct: 302 ATCTNTGQGSYTCSCRPGYTGATCELGIDECDP 334
Score = 37.4 bits (85), Expect = 0.24
Identities = 16/37 (43%), Positives = 18/37 (48%), Gaps = 5/37 (13%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
C C NGGTC G+ F C CP +TGR C
Sbjct: 447 CASSPCANGGTCR-----DGVNDFSCTCPPGYTGRNC 478
Score = 35.8 bits (81), Expect = 0.69
Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 14/72 (19%)
Query: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
A G+ TC GE C P W G C + + CL C C
Sbjct: 198 AFGHFTCGERGEKV---------CNPGWKGPYCTEPI-CLPGCDEQHGFCDKPGE----C 243
Query: 2938 LCTLGWVGRYCE 2949
C +GW GRYC+
Sbjct: 244 KCRVGWQGRYCD 255
Score = 34.3 bits (77), Expect = 2.0
Identities = 16/58 (27%), Positives = 25/58 (43%), Gaps = 7/58 (12%)
Query: 2899 CRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFST 2956
C+C W G C++ + CLH + P + C C GW G +C ++ T
Sbjct: 243 CKCRVGWQGRYCDECIRYPG--CLHGTCQQP-----WQCNCQEGWGGLFCNQDLNYCT 293
Score = 34.3 bits (77), Expect = 2.0
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 7/59 (11%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFF--PSFNGNSYLELP 2159
C C NGG+C + S + C CP F G+ CE A P FNG + P
Sbjct: 332 CDPSPCKNGGSCTDLENS-----YSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 201 bits (511), Expect = 9e-51
Identities = 196/775 (25%), Positives = 314/775 (40%), Gaps = 103/775 (13%)
Query: 2375 CENNPCGNGATCVPKS-GTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYS 2433
C++ PC +G TC + G C CP GR G +C + P F G + + AY
Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYH 1392
Query: 2434 RISDISFHYEFHLKFQLANNHSALQ-NNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYN 2492
+ +LA AL+ L+ + G G DFLA+ LL+G V ++
Sbjct: 1393 TL-------------RLALEFRALEPQGLLLYNGNA----RGKDFLALALLDGRVQLRFD 1435
Query: 2493 LGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYV 2552
GSG A + S H + L + ++ G L VD +P GLN+ + +V
Sbjct: 1436 TGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFV 1495
Query: 2553 GGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHAS 2612
GG E + G +GCI L V ++ LG G G VG+C
Sbjct: 1496 GGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQR----LELGIGPGAATRGSGVGECGDH 1551
Query: 2613 PCSLMKCGNGGTC--IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
PC C G C +E+G +C C G G C + S C P + C A C
Sbjct: 1552 PCLPNPCHGGAPCQNLEAGR-FHCQCPPGRVGPTCADEKSPCQP-----NPCHGAAPCRV 1605
Query: 2671 LPHGYT-CFCPLGTTGIYCEQALSISDPS---------FRSNELSWMSFASFHVRKKTHI 2720
LP G C CPLG G +C+ A S D S F EL + + + +K +
Sbjct: 1606 LPEGGAQCECPLGREGTFCQTA-SGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMAL 1664
Query: 2721 QLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTING 2780
++ F G+L Y Q + GDF+ ++L + ++ RY+LG ++ + + VT+
Sbjct: 1665 EVVFLARGPSGLLLYNGQKTDGK-GDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGA 1723
Query: 2781 STWHIIKAGRVGAEGYLDL-DGINVTEKASTKMSSLDTNTDFYIGGVSSLN-LVNPMAIE 2838
W + R G +G L + DG V ++ + L+ Y+GG + L A+
Sbjct: 1724 --WTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVS 1781
Query: 2839 NEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTAC---GYNTCRNGGECTVNGT 2895
+ GF G I+ V + ++L LT +V G C + C NG C
Sbjct: 1782 S---GFDGAIQLVSLGGRQL-LTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREA 1837
Query: 2896 TFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFS 2955
+ C C ++G C + G ++
Sbjct: 1838 AYVCLCPGGFSGPHCEK--------------------------------GLVEKSAGDVD 1865
Query: 2956 TAKFMGNSYIKYIDP-NYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLH 3014
T F G ++++Y++ + LQ L+ T T+GL++W G A E D++A+ +
Sbjct: 1866 TLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKA-TERADYVALAIV 1924
Query: 3015 NQTLKIAVNLGE-----RISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSED 3069
+ L+++ NLG R +VP++ N+W VV + Q + N ++
Sbjct: 1925 DGHLQLSYNLGSQPVVLRSTVPVN-------TNRWLRVVAHREQREGSLQVGNEAPVTG- 1976
Query: 3070 IDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKNI 3124
L+ DG +LGG V + + T FVG ++DVV + P ++
Sbjct: 1977 -SSPLGATQLDTDGALWLGGLP-ELPVGPALPKAYGTGFVGCLRDVVVGRHPLHL 2029
Score = 194 bits (493), Expect = 1e-48
Identities = 206/785 (26%), Positives = 323/785 (41%), Gaps = 105/785 (13%)
Query: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELP 2159
P C C +GGTC L G F C CP G CEK G P+F G S+L P
Sbjct: 1330 PKPCDSQPCFHGGTCQDWALGGG---FTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFP 1386
Query: 2160 FLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNS 2219
L+ T+ + L + G +LY NGN GK FL L L++GR +++ G+
Sbjct: 1387 TLRAY------HTLRLALEFRALEPQGLLLY-NGNARGKDFLALALLDGRVQLRFDTGSG 1439
Query: 2220 QNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQA 2279
+LT + + + + + G+ ++ DG+ PV + +
Sbjct: 1440 PAVLTSAV--PVEPGQWHRLELSRHWRRGT--------LSVDGETPVLGESPSGTDGLNL 1489
Query: 2280 YFESMFLGHIP---ANVQIHKKAGPVYGFRGCILDLQVNNKEFFI---IDEARHGKNIEN 2333
+ +F+G +P A V + + G RGCI L VNN+ + A G +
Sbjct: 1490 DTD-LFVGGVPEDQAAVALERTFVGA-GLRGCIRLLDVNNQRLELGIGPGAATRGSGVGE 1547
Query: 2334 CHVPWCAHHLCRNNGTCISDNENLF-CECPRLYSGKLC--QFASCENNPCGNGATC--VP 2388
C C + C C + F C+CP G C + + C+ NPC A C +P
Sbjct: 1548 CGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLP 1607
Query: 2389 KSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFG--YTSFLAYSRISDISFH-YEFH 2445
+ G C CP GR G C A SG D G F +S + H +
Sbjct: 1608 EGGAQ--CECPLGREGTFCQTA--------SGQDGSGPFLADFNGFSHLELRGLHTFARD 1657
Query: 2446 LKFQLANNHSAL---QNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRS 2502
L ++A L + L+ + GQK G DF+++ L + + + Y+LG G A IRS
Sbjct: 1658 LGEKMALEVVFLARGPSGLLLYNGQKTDGKG--DFVSLALRDRRLEFRYDLGKGAAVIRS 1715
Query: 2503 -EPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPD 2561
EP+ L V L + ++G L+V D +P LN+ YVGG +++
Sbjct: 1716 REPVTLGAWTR-VSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSK- 1773
Query: 2562 LLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMK--- 2618
L A +GF G I + + R L PE H V PC+
Sbjct: 1774 -LARAAAVSSGFDGAIQLVSLGG------RQLLTPE-HVLRQVDVTSFAGHPCTRASGHP 1825
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
C NG +C+ + C C G+ G HC +G S T
Sbjct: 1826 CLNGASCVPREAAYVCLCPGGFSGP-----------------HCEKGLVEKSAGDVDTLA 1868
Query: 2679 CPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQ 2738
G T + A++ S+ + +SN H +L + A G++ ++ +
Sbjct: 1869 FD-GRTFVEYLNAVTESEKALQSN----------------HFELSLRTEATQGLVLWSGK 1911
Query: 2739 HLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLD 2798
+ D++ +++V+ +QL YNLG + ++L + V +N + W + A R EG L
Sbjct: 1912 --ATERADYVALAIVDGHLQLSYNLGSQPVVLRS--TVPVNTNRWLRVVAHREQREGSLQ 1967
Query: 2799 L-DGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQE 2857
+ + VT + + LDT+ ++GG+ L V P + GF GC+R V++
Sbjct: 1968 VGNEAPVTGSSPLGATQLDTDGALWLGGLPELP-VGPALPKAYGTGFVGCLRDVVVGRHP 2026
Query: 2858 LQLTE 2862
L L E
Sbjct: 2027 LHLLE 2031
Score = 110 bits (275), Expect = 2e-23
Identities = 152/714 (21%), Positives = 271/714 (37%), Gaps = 97/714 (13%)
Query: 1888 YYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYH 1947
+ G S+L F + ++LEF+ GLLLY + N F+ L + +G ++
Sbjct: 1377 FEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLY---NGNARGKDFLALALLDGRVQLR 1433
Query: 1948 FYCPGEAKFKSINTTVRVDNGQKYTLLI----RQELDPCNAELTILGRNTQICESINHVL 2003
F + + V V+ GQ + L + R+ + E +LG + + +N
Sbjct: 1434 FDTGSGPAV--LTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLN--- 1488
Query: 2004 GKPLPKSGSVFIGGFPDLHGKIQMPVPV--KNFTGCIEVIEINNWRSFI---PSKAVKNY 2058
+F+GG P+ + + GCI ++++NN R + P A +
Sbjct: 1489 -----LDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGS 1543
Query: 2059 HINNCRSQGFMLSPTASFVDASDVTQG---VDTMWTSVSPSVA-APSVCQQDVCHNGGTC 2114
+ C + +P ++ G V P+ A S CQ + CH C
Sbjct: 1544 GVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPC 1603
Query: 2115 HAIFLSSGIVSFQCDCPLHFTGRFCEKDAGL-----FFPSFNGNSYLELPFLKFVLEKEH 2169
L G QC+CPL G FC+ +G F FNG S+LEL L ++
Sbjct: 1604 RV--LPEG--GAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLH-TFARDL 1658
Query: 2170 NRTVTIYLTIKTNSLNGTILYSNGNNCGK-QFLHLFLVEGRPSVKYGCGNSQNILTVSAN 2228
+ + + +G +LY+ GK F+ L L + R +Y G + + +
Sbjct: 1659 GEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAV--IRSR 1716
Query: 2229 YSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGH 2288
+ A+T +++ G+ V G P ++ + H E +++G
Sbjct: 1717 EPVTLGAWTRVSLERNGRKGALRV---------GDGPRVLGESPVPHTVLNLKEPLYVGG 1767
Query: 2289 IPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAH---HLCR 2345
P ++ + A GF G I + + ++ + ++ + C H C
Sbjct: 1768 APDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCL 1827
Query: 2346 NNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGP 2405
N +C+ C CP +SG C+ V KS D+ L
Sbjct: 1828 NGASCVPREAAYVCLCPGGFSGPHCE------------KGLVEKSAGDVDTLA------- 1868
Query: 2406 LCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFT 2465
F G Y + + S + S H+E L+ + L+ ++
Sbjct: 1869 ------------FDGRTFVEYLNAVTESEKALQSNHFELSLRTEAT-------QGLVLWS 1909
Query: 2466 GQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSE-PLNLSLGVHTVHLGKFFQEGW 2524
G+ D++A+ +++G + SYNLGS +RS P+N + + V + +EG
Sbjct: 1910 GK---ATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVV-AHREQREGS 1965
Query: 2525 LKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEY-TPDLLPNGADFKNGFQGCI 2577
L+V + + +P L+ ++GG E LP + GF GC+
Sbjct: 1966 LQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKA--YGTGFVGCL 2017
Score = 60.8 bits (146), Expect = 2e-08
Identities = 121/556 (21%), Positives = 176/556 (31%), Gaps = 133/556 (23%)
Query: 748 CKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKN--NSTCTDLYKSYRCECTSGWTGQN 805
C+ + + VC + EG + S CK +PC + C +Y EC
Sbjct: 172 CRGMLCGFGAVCEPNAEGP--GRASCVCKKSPCPSVVAPVCGSDASTYSNECEL--QRAQ 227
Query: 806 CSEEIN-------ECDS-DPCMN-----GGLCHESTIPGQFVCLCPPLYTG--------- 843
CS++ C S DPC N G C S CLCP G
Sbjct: 228 CSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGS 287
Query: 844 -------------QFCHQRYNLCDLLHNPCRNNSTCL-ALVDANQHCICREEFEGKNCEI 889
+ C ++ N+ PC C AL D ++ C +
Sbjct: 288 DGADYPGECQLLRRACARQENVFKKFDGPC---DPCQGALPDPSRSCRVNPRTRRPEMLL 344
Query: 890 DVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLC--EIEINECSS-----EPCKNNGT 942
+ C GD N + R G + L ++ +C EPC+ N
Sbjct: 345 RPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAV 404
Query: 943 CVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG-YNCLCA-PGYT-GI 999
C+ R C+C D C DG Y +CA G T
Sbjct: 405 CLSRRGRPRCSC----------------------DRVTC----DGAYRPVCAQDGRTYDS 438
Query: 1000 NCEINLDECLSE---PCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRC 1056
+C EC + P H G C S G C A + N C
Sbjct: 439 DCWRQQAECRQQRAIPSKHQGPC--------DQAPSPCLGVQCAFGATCAVKNGQAACEC 490
Query: 1057 TELINE-YPCSCDADGTS--TQCKIKINDCT---SIPCMNEGFCQKSAHGFTCICPRGYT 1110
+ + Y C +DG + + C+++ CT I +G C + C +
Sbjct: 491 LQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDR--------CGQCRF 542
Query: 1111 GAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPC 1170
GA CE C P + + L +C GHT+ C+ +I+++ S+ PC
Sbjct: 543 GALCEAETGRCVCP--SECVALAQPVC-GSDGHTYPSECMLHVHACTHQISLHVASAGPC 599
Query: 1171 LHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTC 1230
C D + + C G CV C PG C G
Sbjct: 600 ---ETCGDAVCAFGAVCSAG---------------QCVCPRCEHPPPGPVC----GSDGV 637
Query: 1231 SIGLLCGDEIRRITCL 1246
+ G C E+R CL
Sbjct: 638 TYGSAC--ELREAACL 651
Score = 57.8 bits (138), Expect = 2e-07
Identities = 175/881 (19%), Positives = 267/881 (30%), Gaps = 156/881 (17%)
Query: 282 CDEQFSGP---FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSL 338
C+ GP C PC S++ +C + +S Y+ EC + + + + S
Sbjct: 183 CEPNAEGPGRASCVCKKSPCPSVV---APVCGSDASTYSNECELQRAQCSQQRRIRLLSR 239
Query: 339 VPCQNGTDCIKISNDVMCICSPIFTDLLCKSI-QTSCESFPLRNNATCKKCEKDYPCSCI 397
PC + C ++ C+ L + +C P C DYP
Sbjct: 240 GPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAP--EGTVCGSDGADYP---- 293
Query: 398 SGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP----------GCTKNPCWF 447
C+LL C +E N+ +F C P C NP
Sbjct: 294 ------------GECQLLRRACARQE---NVFKKFDGPCDPCQGALPDPSRSCRVNPRTR 338
Query: 448 LKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAG-SEGEKCQGVIDAYFFLAAN 506
+ L + C +C D G +E +G +G + G Q V
Sbjct: 339 RPEMLLRPES---CPARQAPVCGDDG-VTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQ 394
Query: 507 CTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLEN 566
C E + N+ C G CSC YR +C G Y ++
Sbjct: 395 CPEPCRF-------NAVC-LSRRGRPR-----CSCDRVTCDGAYRPVC--AQDGRTY-DS 438
Query: 567 TTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGL--CLAL- 623
Q+ EC+ + + P +G C + N + L C +L
Sbjct: 439 DCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLY 498
Query: 624 SHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDID 683
C G+ + CE++ + +C G R +C G CE +
Sbjct: 499 DPVCGSDGVT--YGSACELE-----ATACTLGREIQVARKGPCDRCGQCRFGALCEAETG 551
Query: 684 ECASHPCKNGATCIDQP------GNYFCQCV---------PPFKVVDGFSC-LCNPGYVG 727
C C + + QP Y +C+ V C C
Sbjct: 552 RCV---CPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCA 608
Query: 728 IRCEQDIDDCILNACEH---NSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNS 784
C+ CEH C ++Y C + + E + PC+
Sbjct: 609 FGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCE--- 665
Query: 785 TCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC-MNGGLCHESTIPGQFVC--LCPPLY 841
+ EC SG +G S E +C+ + C GG+ E + G VC C +
Sbjct: 666 ---------QAECGSGGSG---SGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVP 713
Query: 842 TGQFCHQ---RYNL-CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFL 897
C Y+ C+L C + CR + C
Sbjct: 714 GSPVCGSDGVTYSTECELKKARCESQRGLYVAAQG----ACRGPTFAPLPPVAPLHC--- 766
Query: 898 SCQDYGDCEDMVNNFR----------CICRP-GFSGSLCEIEINECSSEPCKNNGTCVDL 946
+ YG C+D + R C C P G G C+ +CS P C
Sbjct: 767 AQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRC--- 823
Query: 947 TNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYN----CLCAPGYTGINCE 1002
CEP + + + +PC + R D C C PG G C
Sbjct: 824 -----DRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKC- 877
Query: 1003 INLDECLSEPCLHDGVC-IDGINHYTCDCKSGFFGTHC--ETNANDCLSNPCLHGRCTEL 1059
+C L C D TC FG C E+ + C+ C C E
Sbjct: 878 ---GQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCV---CPMLTCPEA 931
Query: 1060 INEYPCSCDADGTSTQCKIKINDC---TSIPCMNEGFCQKS 1097
C D +C++K C I + G CQ++
Sbjct: 932 NATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEA 972
Score = 57.8 bits (138), Expect = 2e-07
Identities = 138/639 (21%), Positives = 198/639 (30%), Gaps = 141/639 (22%)
Query: 662 RGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLC 721
RG +K G QC+ D+C PC+ A C+ + G C C D +C
Sbjct: 377 RGLLLQKVRSG----QCQ-GRDQCPE-PCRFNAVCLSRRGRPRCSC-------DRVTC-- 421
Query: 722 NPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCK 781
G C QD + + C+ Q S +G C+Q + C C
Sbjct: 422 -DGAYRPVCAQDGRTYDSDCWRQQAECRQ-----QRAIPSKHQGP-CDQAPSPCLGVQCA 474
Query: 782 NNSTCTDLYKSYRCECTSGWTGQNCSEEINE-CDSDPCMNGGLCH-EST--IPGQFVCLC 837
+TC CEC Q CS + C SD G C E+T G+ + +
Sbjct: 475 FGATCAVKNGQAACECL-----QACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVA 529
Query: 838 PPLYTGQFCHQRYN-LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC-- 894
+ R+ LC+ C S C+AL A C C + V C
Sbjct: 530 RKGPCDRCGQCRFGALCEAETGRCVCPSECVAL--AQPVCGSDGHTYPSECMLHVHACTH 587
Query: 895 -LFLSCQDYGDCE---DMVNNFRCICRPGFSGSLCEIEINECSSEP----CKNNGTCVDL 946
+ L G CE D V F +C G + C P C ++G
Sbjct: 588 QISLHVASAGPCETCGDAVCAFGAVCSAG------QCVCPRCEHPPPGPVCGSDGV---- 637
Query: 947 TNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGI----NCE 1002
+ CE + + + + PC E C G +G +CE
Sbjct: 638 --TYGSACELREAACLQQTQIEEARAGPCEQAE------------CGSGGSGSGEDGDCE 683
Query: 1003 INL---------DECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH 1053
L ++ PC+ D C C + T CE C S L+
Sbjct: 684 QELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLY 743
Query: 1054 ----GRCTE------------LINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKS 1097
G C + P C D + + + C S
Sbjct: 744 VAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPS------------ 791
Query: 1098 AHGFTCIC-PRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQ 1156
C C P G G C+ + C+ C G G RC PGF
Sbjct: 792 ----ACQCNPHGSYGGTCDPATGQCS--------------CRPGVGGLRCDRCEPGFWNF 833
Query: 1157 FCEININECSSSPCL---HGA---DCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHE 1210
+ +PC GA DCE +C C+PG +G C +C +
Sbjct: 834 RGIVTDGRSGCTPCSCDPQGAVRDDCEQMTG--LCSCKPGVAGPKCG---QCPDGRALGP 888
Query: 1211 LCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPI 1249
E + + C M C G C +E C+ P+
Sbjct: 889 AGCEADASAPATCAE--MRCEFGARCVEESGSAHCVCPM 925
Score = 47.8 bits (112), Expect = 2e-04
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 775 CKMNPCKNNSTCTDLYKS-YRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIP-GQ 832
C NPC + C +L + C+C G G C++E + C +PC C +P G
Sbjct: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR--VLPEGG 1610
Query: 833 FVCLCPPLYTGQFC 846
C CP G FC
Sbjct: 1611 AQCECPLGREGTFC 1624
Score = 47.4 bits (111), Expect = 2e-04
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 932 CSSEPCKNNGTCVDL-TNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENC-VYRTDGYN 989
C PC C +L RF C C P GP C + + C+ +PC C V G
Sbjct: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
Query: 990 CLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH 1025
C C G G C+ + S P L D +G +H
Sbjct: 1613 CECPLGREGTFCQTASGQDGSGPFLAD---FNGFSH 1645
Score = 46.6 bits (109), Expect = 4e-04
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 810 INECDSDPCM----NGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNST 865
+ EC PC+ +GG ++ G+F C CPP G C + C NPC +
Sbjct: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ--PNPCHGAAP 1602
Query: 866 CLALVDANQHCICREEFEGKNCE 888
C L + C C EG C+
Sbjct: 1603 CRVLPEGGAQCECPLGREGTFCQ 1625
Score = 45.8 bits (107), Expect = 7e-04
Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 16/97 (16%)
Query: 685 CASHPCKNGATCID-QPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACE 743
C +PC GA C + + G + CQC PG VG C + C N C
Sbjct: 1553 CLPNPCHGGAPCQNLEAGRFHCQCP--------------PGRVGPTCADEKSPCQPNPCH 1598
Query: 744 HNSTCKDL-HLSYQCVCLSDWEGNFCEQESNECKMNP 779
+ C+ L QC C EG FC+ S + P
Sbjct: 1599 GAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 737 CILNACEHNSTCKDLHLS-YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYK-SYR 794
C+ N C + C++L + C C G C E + C+ NPC + C L + +
Sbjct: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
Query: 795 CECTSGWTGQNCSEEINECDSDP 817
CEC G G C + S P
Sbjct: 1613 CECPLGREGTFCQTASGQDGSGP 1635
Score = 44.7 bits (104), Expect = 0.001
Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 1134 GGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSG 1193
GG + P H + F+G C S PCL+GA C YVC C G+SG
Sbjct: 1794 GGRQLLTPEHVLRQVDVTSFAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSG 1849
Query: 1194 HHCENEL 1200
HCE L
Sbjct: 1850 PHCEKGL 1856
Score = 42.7 bits (99), Expect = 0.006
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 7/81 (8%)
Query: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHG--NCSNIT 274
C PC C +N + + C C P G C++ CQP+ C HG C +
Sbjct: 1553 CLPNPCHGGAPC----QNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPC-HGAAPCRVLP 1607
Query: 275 SNSFICECDEQFSGPFCEVSA 295
CEC G FC+ ++
Sbjct: 1608 EGGAQCECPLGREGTFCQTAS 1628
Score = 41.6 bits (96), Expect = 0.013
Identities = 20/36 (55%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 1083 CTSIPCMNEGFCQKSA--HGFTCICPRGYTGAYCEK 1116
C S PC + G CQ A GFTC CP G GA CEK
Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
Score = 40.4 bits (93), Expect = 0.028
Identities = 15/36 (41%), Positives = 19/36 (52%)
Query: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQ 848
CDS PC +GG C + + G F C CP G C +
Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
Score = 39.3 bits (90), Expect = 0.062
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 3/79 (3%)
Query: 1040 ETNANDCLSNPCLHGR-CTEL-INEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKS 1097
E + CL NPC G C L + C C C + + C PC C+
Sbjct: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
Query: 1098 AHGFT-CICPRGYTGAYCE 1115
G C CP G G +C+
Sbjct: 1607 PEGGAQCECPLGREGTFCQ 1625
Score = 38.9 bits (89), Expect = 0.081
Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 2/89 (2%)
Query: 894 CLFLSCQDYGDCEDM-VNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDL-TNRFF 951
CL C C+++ F C C PG G C E + C PC C L
Sbjct: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
Query: 952 CNCEPEYHGPFCELDVNKCKISPCLDEEN 980
C C G FC+ + P L + N
Sbjct: 1613 CECPLGREGTFCQTASGQDGSGPFLADFN 1641
Score = 38.9 bits (89), Expect = 0.081
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 1/68 (1%)
Query: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCED-HINGYVCKCQP 1189
C G C + F C+C PG G C + C +PC A C G C+C
Sbjct: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPL 1617
Query: 1190 GWSGHHCE 1197
G G C+
Sbjct: 1618 GREGTFCQ 1625
Score = 38.5 bits (88), Expect = 0.11
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 2/38 (5%)
Query: 1165 CSSSPCLHGADCEDHI--NGYVCKCQPGWSGHHCENEL 1200
C S PC HG C+D G+ C C G G CE L
Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
Score = 38.5 bits (88), Expect = 0.11
Identities = 25/85 (29%), Positives = 32/85 (37%), Gaps = 2/85 (2%)
Query: 970 CKISPCLDEENCVYRTDG-YNCLCAPGYTGINCEINLDECLSEPCLHDGVC-IDGINHYT 1027
C +PC C G ++C C PG G C C PC C +
Sbjct: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
Query: 1028 CDCKSGFFGTHCETNANDCLSNPCL 1052
C+C G GT C+T + S P L
Sbjct: 1613 CECPLGREGTFCQTASGQDGSGPFL 1637
Score = 38.5 bits (88), Expect = 0.11
Identities = 12/32 (37%), Positives = 19/32 (59%)
Query: 1087 PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
PC+N C + C+CP G++G +CEK +
Sbjct: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
Score = 37.4 bits (85), Expect = 0.24
Identities = 16/34 (47%), Positives = 21/34 (61%)
Query: 974 PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDE 1007
PCL+ +CV R Y CLC G++G +CE L E
Sbjct: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
Score = 36.6 bits (83), Expect = 0.40
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 1159 EININECSSSPCLHGADCEDHING-YVCKCQPGWSGHHCENELE-CIPNSC--VHELCME 1214
E + C +PC GA C++ G + C+C PG G C +E C PN C +
Sbjct: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
Query: 1215 NEPGSTCLCTPG 1226
E G+ C C G
Sbjct: 1607 PEGGAQCECPLG 1618
Score = 36.2 bits (82), Expect = 0.53
Identities = 41/185 (22%), Positives = 57/185 (30%), Gaps = 34/185 (18%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELD---------------ACSFKPCKNNGS 227
C+ HG T C C+P G C + C+ C G+
Sbjct: 795 CNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGA 854
Query: 228 CINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQ------PHVCFHGNCSNITSNSFICE 281
R++ ++ C C P G C GQC P C + T CE
Sbjct: 855 V---RDDCEQMTGLCSCKPGVAGPKC----GQCPDGRALGPAGCEADASAPATCAEMRCE 907
Query: 282 ----CDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS 337
C E+ C C K +C + Y EC + + +S S
Sbjct: 908 FGARCVEESGSAHCVCPMLTCPEANATK--VCGSDGVTYGNECQLKTIACRQGLQISIQS 965
Query: 338 LVPCQ 342
L PCQ
Sbjct: 966 LGPCQ 970
Score = 35.8 bits (81), Expect = 0.69
Identities = 26/90 (28%), Positives = 28/90 (31%), Gaps = 6/90 (6%)
Query: 1083 CTSIPCMNEGFCQKSAHG-FTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGP 1141
C PC CQ G F C CP G G C C C C P
Sbjct: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNP-----CHGAAPCRVLP 1607
Query: 1142 GHTFDCRCLPGFSGQFCEININECSSSPCL 1171
C C G G FC+ + S P L
Sbjct: 1608 EGGAQCECPLGREGTFCQTASGQDGSGPFL 1637
Score = 35.4 bits (80), Expect = 0.90
Identities = 21/69 (30%), Positives = 26/69 (37%), Gaps = 2/69 (2%)
Query: 641 EIDTEDCKSASCKNGTTSTHLR-GYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699
E C C G +L G F +C PG G C + C +PC A C
Sbjct: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
Query: 700 P-GNYFCQC 707
P G C+C
Sbjct: 1607 PEGGAQCEC 1615
Score = 35.4 bits (80), Expect = 0.90
Identities = 21/82 (25%), Positives = 28/82 (34%), Gaps = 1/82 (1%)
Query: 856 LHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDM-VNNFRC 914
L NPC + C L HC C G C + C C C + +C
Sbjct: 1554 LPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQC 1613
Query: 915 ICRPGFSGSLCEIEINECSSEP 936
C G G+ C+ + S P
Sbjct: 1614 ECPLGREGTFCQTASGQDGSGP 1635
Score = 35.0 bits (79), Expect = 1.2
Identities = 16/48 (33%), Positives = 21/48 (43%), Gaps = 6/48 (12%)
Query: 257 IGQCQPHVCF----HGN--CSNITSNSFICECDEQFSGPFCEVSAKPC 298
+G+C H C HG C N+ + F C+C GP C PC
Sbjct: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPC 1592
Score = 34.7 bits (78), Expect = 1.5
Identities = 47/197 (23%), Positives = 73/197 (37%), Gaps = 50/197 (25%)
Query: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
CQ+++++ G C S +C C P G Y G+C
Sbjct: 774 CQDNITAARGVGLAGCPS-------ACQCNP--HGSY--------------GGTC----- 805
Query: 234 NWDEQAYECVCHPPFTGKNCSEIIGQCQPHVC-FHGNCSNITSNSFICECDEQFS-GPFC 291
D +C C P G C +C+P F G ++ S C CD Q + C
Sbjct: 806 --DPATGQCSCRPGVGGLRCD----RCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDC 859
Query: 292 E-----VSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTD 346
E S KP V+ K G CP+ + C +S+ + + + C+ G
Sbjct: 860 EQMTGLCSCKPGVAGP--KCGQCPDGRALGPAGCEADASAP------ATCAEMRCEFGAR 911
Query: 347 CIKISNDVMCICSPIFT 363
C++ S C+C P+ T
Sbjct: 912 CVEESGSAHCVC-PMLT 927
Score = 34.7 bits (78), Expect = 1.5
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 18/65 (27%)
Query: 670 VPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIR 729
V F G C + HPC NGA+C+ + Y CLC G+ G
Sbjct: 1810 VTSFAGHPCT----RASGHPCLNGASCVPREAAYV--------------CLCPGGFSGPH 1851
Query: 730 CEQDI 734
CE+ +
Sbjct: 1852 CEKGL 1856
Score = 34.3 bits (77), Expect = 2.0
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1008 CLSEPCLHDGVCIDGI--NHYTCDCKSGFFGTHCE 1040
C S+PC H G C D +TC C +G G CE
Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
Score = 34.3 bits (77), Expect = 2.0
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 1012 PCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
PCL+ C+ Y C C GF G HCE
Sbjct: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
Score = 33.9 bits (76), Expect = 2.6
Identities = 84/443 (18%), Positives = 124/443 (27%), Gaps = 111/443 (25%)
Query: 905 CEDMVNNFRCICRPGFSG---SLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGP 961
C M+ F +C P G + C C PC + V C + +
Sbjct: 172 CRGMLCGFGAVCEPNAEGPGRASCV-----CKKSPCPSVVAPV-------CGSDASTYSN 219
Query: 962 FCELDVNKCKIS---------PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEP 1012
CEL +C PC + C T + CA G L+
Sbjct: 220 ECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADG----------LTAS 269
Query: 1013 CLHDGVCIDGINHYTCDCKSGFFGTHCETNANDC---------LSNPCLHGRCTELINEY 1063
CL C C + C+ C PC C + +
Sbjct: 270 CLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPC--DPCQGALPDP 327
Query: 1064 PCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGA----------- 1112
SC + + + ++ + S P C + C G +GA
Sbjct: 328 SRSCRVNPRTRRPEMLLRP-ESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRS 386
Query: 1113 -YCEKSIDNCAEPELNSVICLNGG------------------ICV-DGPGHTFDC----- 1147
C+ D C EP + +CL+ +C DG + DC
Sbjct: 387 GQCQGR-DQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQA 445
Query: 1148 -----RCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWS---------- 1192
R +P C+ + C C GA C C+C S
Sbjct: 446 ECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSD 505
Query: 1193 ----GHHCENELECIPNSCVHELCMENE-PGSTCLCTPGFMTCSIGLLCGDEIRRITCLT 1247
G CE LE + E+ + + P C C G LC E R C +
Sbjct: 506 GVTYGSACE--LEATACTLGREIQVARKGPCDRC------GQCRFGALCEAETGRCVCPS 557
Query: 1248 PIFQRTDPISTQTYTIPPSETLV 1270
P+ PSE ++
Sbjct: 558 ECVALAQPVCGSDGHTYPSECML 580
Score = 33.1 bits (74), Expect = 4.4
Identities = 15/55 (27%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
Query: 758 VCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINE 812
V ++ + G+ C + S +PC N ++C +Y C C G++G +C + + E
Sbjct: 1808 VDVTSFAGHPCTRASG----HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
Score = 33.1 bits (74), Expect = 4.4
Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 4/45 (8%)
Query: 920 FSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE 964
F+G C S PC N +CV + C C + GP CE
Sbjct: 1813 FAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
Score = 32.7 bits (73), Expect = 5.8
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 932 CSSEPCKNNGTCVD--LTNRFFCNCEPEYHGPFCE 964
C S+PC + GTC D L F C+C G CE
Sbjct: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
Score = 32.7 bits (73), Expect = 5.8
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 372 TSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI 409
T P N A+C E Y C C GF+ +CEK +
Sbjct: 1819 TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
Score = 32.3 bits (72), Expect = 7.6
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 8/50 (16%)
Query: 206 FSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSE 255
F+G C S PC N SC+ + E AY C+C F+G +C +
Sbjct: 1813 FAGHPCTR---ASGHPCLNGASCVPR-----EAAYVCLCPGGFSGPHCEK 1854
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 194 bits (494), Expect = 9e-49
Identities = 211/801 (26%), Positives = 298/801 (37%), Gaps = 228/801 (28%)
Query: 587 RPRCSCSLSYIGRLCVVN-VDYCLGNHSISVHGLCLALSHNCNCSGLQRYER--NICEID 643
+ +C G +CV + D C VHG C+A + C C + C+ D
Sbjct: 91 KSQCCPGFYESGEMCVPHCADKC-------VHGRCIA-PNTCQCEPGWGGTNCSSACDGD 142
Query: 644 T--EDCKS-ASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHP----------C 690
C S CKNG + G C GF+G +CE D C C
Sbjct: 143 HWGPHCTSRCQCKNGALCNPITGACH--CAAGFRGWRCE---DRCEQGTYGNDCHQRCQC 197
Query: 691 KNGATCIDQPGNYFCQCVPPFKVVDGFSC--LCNPGYVGIRCEQDIDDCILNACEHNSTC 748
+NGATC G C+C P + G C LC PG G +CEQ C++ C
Sbjct: 198 QNGATCDHVTGE--CRCPPGYT---GAFCEDLCPPGKHGPQCEQRCP------CQNGGVC 246
Query: 749 KDLHLSYQCVCLSDWEGNFCEQE----------SNECKMNPCKNNSTCTDLYKSYRCECT 798
H++ +C C S W G C Q S EC+ C N TC + +C C+
Sbjct: 247 H--HVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQ---CHNGGTCDAA--TGQCHCS 299
Query: 799 SGWTGQNCSEE-------INECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQR-- 849
G+TG+ C +E + ++ C+NGG C+ + G CLC + G+ C R
Sbjct: 300 PGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYH--VSG--ACLCEAGFAGERCEARLC 355
Query: 850 ----YNL-CDLLHNPCR--NNSTCLALVDANQHCICREEFEGKNCEIDVKDCLF------ 896
Y + CD PC N +C + + C C+ + G C +
Sbjct: 356 PEGLYGIKCDK-RCPCHLENTHSCHPM---SGECACKPGWSGLYCNETCSPGFYGEACQQ 411
Query: 897 -LSCQDYGDCEDMVNNFRCICRPGFSGSLCEIE-------INECSSEPCKNNGTCVDLTN 948
SCQ+ DC+ + +C C PGF G C IN S CKN+ C +
Sbjct: 412 ICSCQNGADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG 469
Query: 949 RFFCNCEPEYHGPFCELDV------------------------------------NKCKI 972
C C+ +HG C + KC++
Sbjct: 470 S--CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCEL 527
Query: 973 SPCLDEE---NCVYRTDGYN----------CLCAPGYTGINCEINLDEC-----LSEPCL 1014
PC D NC R D + C C PG++G++C+ E S PC
Sbjct: 528 -PCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCY 586
Query: 1015 ---------HDGVC--IDGINHYTCD--CKSGFFGTHCETNANDCL--SNPCLHGRCTEL 1059
DG+C G TC C GF+G C C+ S PC H T L
Sbjct: 587 CKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHH--ITGL 644
Query: 1060 INEYPCSCDADGTSTQCKIKI------NDCTSI-PCMNEGFCQKSAHGFTCICPRGYTGA 1112
C C T C +C I C N G C +C C G+ G+
Sbjct: 645 -----CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDR--SCQCYPGWIGS 697
Query: 1113 YCEKSID------NCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEINI---- 1162
C + NC +++ C NG C G +C+C PG++G +C
Sbjct: 698 DCSQPCPPAHWGPNC----IHTCNCHNGAFCSAYDG---ECKCTPGWTGLYCTQRCPLGF 750
Query: 1163 --NECSS-SPCLHGADCEDHINGYVCKCQPGWSGHHCENE-------------LECIPNS 1206
+C+ C +GADC DHI+G C C+ G+ G HCE + +C+ NS
Sbjct: 751 YGKDCALICQCQNGADC-DHISGQ-CTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNS 808
Query: 1207 CVHELCMENEPGSTCLCTPGF 1227
+ TC C+PG+
Sbjct: 809 TCDHIT------GTCYCSPGW 823
Score = 156 bits (395), Expect = 3e-37
Identities = 220/927 (23%), Positives = 317/927 (34%), Gaps = 228/927 (24%)
Query: 136 VNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAW- 194
V S W S Y +TV S P P + C + L+ C+ H A+
Sbjct: 33 VCSHWES----YSVTVQESYPHPFD-------QIYYTSCTDILNWFKCTRHRVSYRTAYR 81
Query: 195 --SKTY---SCHCQPPF--SGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPP 247
KT C P F SG+ C + C+ K +G CI C C P
Sbjct: 82 HGEKTMYRRKSQCCPGFYESGEMC--VPHCADKCV--HGRCIAPNT--------CQCEPG 129
Query: 248 FTGKNCSEII--GQCQPHVCFHGNCSN---ITSNSFICECDEQFSGPFCEVSAKPCVSLL 302
+ G NCS PH C N + C C F G CE +
Sbjct: 130 WGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCE------ 183
Query: 303 FWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIF 362
Y +C + CQNG C ++ + C C P +
Sbjct: 184 ----------QGTYGNDCHQRCQ---------------CQNGATCDHVTGE--CRCPPGY 216
Query: 363 TDLLCKSI------QTSCES-FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLL 415
T C+ + CE P +N C + CSC SG+ C + +
Sbjct: 217 TGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQPCPEGR-F 273
Query: 416 SINCLNEEWCFN----IIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQD 471
NC E C N + C PG T C ++ + + C T C +
Sbjct: 274 GKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC---QDECPVGTYGVLCAETCQ--CVN 328
Query: 472 KGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTE------DATYVNDPEDNNSSC- 524
G L AG GE+C+ + C + + T+ P +C
Sbjct: 329 GGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACK 388
Query: 525 --W------------FPHEGTKEICA--NGCSCLSEEDSQEYRYLCFLRWAG-------N 561
W F E ++IC+ NG C DS + C + G
Sbjct: 389 PGWSGLYCNETCSPGFYGEACQQICSCQNGADC----DSVTGKCTCAPGFKGIDCSTPCP 444
Query: 562 MYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISV----- 616
+ C+++AVC C+C + G C + ++
Sbjct: 445 LGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCL 502
Query: 617 -HGLCLALSHNCNCSGLQRYERNICEIDTED-CKSASCKNGTTSTHLRGYF----FRKCV 670
G C L C C+ R E+ CE+ +D +C +H G +C+
Sbjct: 503 NGGACNTLDGTCTCAPGWRGEK--CELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCL 560
Query: 671 PGFKGTQCEIDIDECASHP-------CKNGATCIDQPGNYFCQCVPPFKVVDGFSC--LC 721
PG+ G C+ E P CKNGA+C P + C+C P F+ G +C +C
Sbjct: 561 PGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC--SPDDGICECAPGFR---GTTCQRIC 615
Query: 722 NPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQ-------ESNE 774
+PG+ G RC Q C+ +S+ H++ C CL + G C + N
Sbjct: 616 SPGFYGHRCSQTCPQCV------HSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC 669
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP-------CMNGGLCHES 827
+ C NN TC + +S C+C GW G +CS+ P C NG C S
Sbjct: 670 AGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFC--S 725
Query: 828 TIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
G+ C C P +TG +C QR C F GK+C
Sbjct: 726 AYDGE--CKCTPGWTGLYCTQR----------------------------CPLGFYGKDC 755
Query: 888 EIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSE----------PC 937
L CQ+ DC+ + + +C CR GF G CE +C S C
Sbjct: 756 ------ALICQCQNGADCDHI--SGQCTCRTGFMGRHCE---QKCPSGTYGYGCRQICDC 804
Query: 938 KNNGTCVDLTNRFFCNCEPEYHGPFCE 964
NN TC +T C C P + G C+
Sbjct: 805 LNNSTCDHITGT--CYCSPGWKGARCD 829
Score = 137 bits (346), Expect = 1e-31
Identities = 213/943 (22%), Positives = 302/943 (32%), Gaps = 229/943 (24%)
Query: 262 PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECP 321
P+VC H ++T E + PF ++ C +L W + C +Y
Sbjct: 31 PNVCSHWESYSVT-------VQESYPHPFDQIYYTSCTDILNWFK--CTRHRVSYR---- 77
Query: 322 KGSSSQNGETDVSEFSLVPC----QNGTDCIKISNDVM----------CICSPIFTDLLC 367
++ ++GE + C ++G C+ D C C P + C
Sbjct: 78 --TAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNC 135
Query: 368 KSIQTSCESFP-------LRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN-- 418
S P +N A C C C +GF CE D C+ +
Sbjct: 136 SSACDGDHWGPHCTSRCQCKNGALCNPITG--ACHCAAGFRGWRCE---DRCEQGTYGND 190
Query: 419 ------CLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGI-CQD 471
C N C ++ G + C PG T C + LC G HG C+
Sbjct: 191 CHQRCQCQNGATCDHVTGECR--CPPGYTGAFC----------EDLCPPGK--HGPQCEQ 236
Query: 472 KGPAQFEYVWQLGFAGSEGEKCQGVIDAYF----FLAANCTEDATYVNDPEDNNSSCWFP 527
+ P Q G C V ++ C + ++ + C
Sbjct: 237 RCPCQ------------NGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCH 284
Query: 528 HEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEA---VCKDE 584
+ GT + C C + + C + G + E +C H + +C+
Sbjct: 285 NGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAG 344
Query: 585 INRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNC----SGLQRYERNIC 640
RC L G L + D H + H C +S C C SGL E
Sbjct: 345 FAGERCEARLCPEG-LYGIKCDKRCPCHLENTHS-CHPMSGECACKPGWSGLYCNETCSP 402
Query: 641 EIDTEDCKS-ASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699
E C+ SC+NG + G C PGFKG C S PC G I+
Sbjct: 403 GFYGEACQQICSCQNGADCDSVTGKC--TCAPGFKGIDC--------STPCPLGTYGINC 452
Query: 700 PGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDD------CILNA-CEHNSTCKDLH 752
C+ VDG SC C G+ G+ C C L C + C L
Sbjct: 453 SSRCGCKNDAVCSPVDG-SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLD 511
Query: 753 LSYQCVCLSDWEGNFCEQESNECKMN-PCKNNSTCTDLYKSY----RCECTSGWTGQNCS 807
+ C C W G CE + C C+ + C C GW+G +C
Sbjct: 512 GT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCD 569
Query: 808 EEINECDSDP-------CMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPC 860
E P C NG C P +C C P + G C +
Sbjct: 570 SVCAEGRWGPNCSLPCYCKNGASCS----PDDGICECAPGFRGTTCQR------------ 613
Query: 861 RNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGF 920
IC F G C C+ S G C + C C PGF
Sbjct: 614 ----------------ICSPGFYGHRCSQTCPQCVHSS----GPCHHITG--LCDCLPGF 651
Query: 921 SGSLCEIEINECSSE----------PCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKC 970
+G+LC C S C NNGTC + C C P + G C
Sbjct: 652 TGALCN---EVCPSGRFGKNCAGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPA 706
Query: 971 KISPCLDEENCVYRTDGYN----------CLCAPGYTGINCEINLD------ECLSEPCL 1014
P NC++ + +N C C PG+TG+ C +C
Sbjct: 707 HWGP-----NCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQC 761
Query: 1015 HDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTST 1074
+G D I+ C C++GF G HCE C S +G C ++ CD
Sbjct: 762 QNGADCDHISGQ-CTCRTGFMGRHCE---QKCPSGTYGYG-CRQI-------CD------ 803
Query: 1075 QCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKS 1117
C+N C TC C G+ GA C+++
Sbjct: 804 -------------CLNNSTCDHITG--TCYCSPGWKGARCDQA 831
Score = 117 bits (293), Expect = 2e-25
Identities = 133/524 (25%), Positives = 181/524 (34%), Gaps = 134/524 (25%)
Query: 771 ESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSD----------PCMN 820
ES E + C + C+C GW G NCS + CD D C N
Sbjct: 100 ESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCS---SACDGDHWGPHCTSRCQCKN 156
Query: 821 GGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICRE 880
G LC+ T C C + G C R C + D +Q C C+
Sbjct: 157 GALCNPIT----GACHCAAGFRGWRCEDR----------CEQGTYGN---DCHQRCQCQN 199
Query: 881 EFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNN 940
G C+ +C CED+ C PG G CE C PC+N
Sbjct: 200 ---GATCDHVTGECRCPPGYTGAFCEDL-------CPPGKHGPQCE---QRC---PCQNG 243
Query: 941 GTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE---ENCVYRTDGYN-------- 989
G C +T C+C + G C PC + +NC +N
Sbjct: 244 GVCHHVTGE--CSCPSGWMGTVCG--------QPCPEGRFGKNCSQECQCHNGGTCDAAT 293
Query: 990 --CLCAPGYTGINCEINLDEC----LSEPCLHDGVCIDGINHY----TCDCKSGFFGTHC 1039
C C+PGYTG C+ DEC C C++G Y C C++GF G C
Sbjct: 294 GQCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERC 350
Query: 1040 ETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA 1098
E L L+G +C + C C + T + C +C P + +C ++
Sbjct: 351 EAR----LCPEGLYGIKCDKR-----CPCHLENTHS-CHPMSGECACKPGWSGLYCNET- 399
Query: 1099 HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFC 1158
C G+ G C++ C NG C G C C PGF G C
Sbjct: 400 ------CSPGFYGEACQQICS-----------CQNGADCDSVTGK---CTCAPGFKGIDC 439
Query: 1159 EI-------NINECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELEC--------- 1202
IN S C + A C ++G C C+ GW G C + C
Sbjct: 440 STPCPLGTYGINCSSRCGCKNDAVCSP-VDGS-CTCKAGWHGVDCS--IRCPSGTWGFGC 495
Query: 1203 -IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
+ C++ G TC C PG+ L C D + C
Sbjct: 496 NLTCQCLNGGACNTLDG-TCTCAPGWRGEKCELPCQDGTYGLNC 538
Score = 50.1 bits (118), Expect = 4e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 13/80 (16%)
Query: 2880 GYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQ 2931
G TC N G C N SC+C P W G+ C+Q +C++ C + + C
Sbjct: 671 GICTCTNNGTC--NPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFC---S 725
Query: 2932 SFSYSCLCTLGWVGRYCENK 2951
++ C CT GW G YC +
Sbjct: 726 AYDGECKCTPGWTGLYCTQR 745
Score = 48.5 bits (114), Expect = 1e-04
Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 12/77 (15%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPH 2673
C N GTC S C C GW GS C++ C P H P+ +C GA C + +
Sbjct: 675 CTNNGTCNPIDRS--CQCYPGWIGSDCSQ---PCPPAHWGPNCIHTCNCHNGAFCSA--Y 727
Query: 2674 GYTCFCPLGTTGIYCEQ 2690
C C G TG+YC Q
Sbjct: 728 DGECKCTPGWTGLYCTQ 744
Score = 43.5 bits (101), Expect = 0.003
Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 13/72 (18%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPHGYTC 2677
G CI T C C GW G+ C+ S CD +H PH C GA C P C
Sbjct: 116 GRCIAPNT---CQCEPGWGGTNCS---SACDGDHWGPHCTSRCQCKNGALC--NPITGAC 167
Query: 2678 FCPLGTTGIYCE 2689
C G G CE
Sbjct: 168 HCAAGFRGWRCE 179
Score = 42.7 bits (99), Expect = 0.006
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 15/76 (19%)
Query: 2884 CRNGGEC-TVNGTTFSCRCLPDWAGNTC-------NQSVSCLNNL-CLHQSLCIPDQSFS 2934
C NGG C T++GT C C P W G C ++C C H C P
Sbjct: 501 CLNGGACNTLDGT---CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG-- 555
Query: 2935 YSCLCTLGWVGRYCEN 2950
C C GW G +C++
Sbjct: 556 -HCRCLPGWSGVHCDS 570
Score = 42.0 bits (97), Expect = 0.010
Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 18/94 (19%)
Query: 2323 DEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--------FAS 2374
D G +CH C+N TC D+ C CP Y+G C+
Sbjct: 180 DRCEQGTYGNDCH----QRCQCQNGATC--DHVTGECRCPPGYTGAFCEDLCPPGKHGPQ 233
Query: 2375 CENN-PCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
CE PC NG C +G C CP G G +C
Sbjct: 234 CEQRCPCQNGGVCHHVTGE---CSCPSGWMGTVC 264
Score = 39.7 bits (91), Expect = 0.048
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 16/80 (20%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP-EHDPPHH----CSRGATCISLP 2672
+C NG TC + C C G+ G+FC + C P +H P C G C
Sbjct: 196 QCQNGATC--DHVTGECRCPPGYTGAFCED---LCPPGKHGPQCEQRCPCQNGGVC---- 246
Query: 2673 HGYT--CFCPLGTTGIYCEQ 2690
H T C CP G G C Q
Sbjct: 247 HHVTGECSCPSGWMGTVCGQ 266
Score = 39.7 bits (91), Expect = 0.048
Identities = 35/113 (30%), Positives = 40/113 (35%), Gaps = 29/113 (25%)
Query: 2602 AGRSVGQCHASPCSL----MKCGNGGTCIESGT------SVYCNCTTGWKGSFCTETVST 2651
AG + +C A C +KC C T S C C GW G +C E T
Sbjct: 343 AGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNE---T 399
Query: 2652 CDPEH-----DPPHHCSRGATCISLPHGYTCF-----------CPLGTTGIYC 2688
C P C GA C S+ TC CPLGT GI C
Sbjct: 400 CSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINC 452
Score = 38.9 bits (89), Expect = 0.081
Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 13/81 (16%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS--------CLNNLCLHQSLCIPDQSFSY 2935
C NG C+ C+C P W G C Q L C + + C S
Sbjct: 718 CHNGAFCSAYDG--ECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC---DHISG 772
Query: 2936 SCLCTLGWVGRYCENKTSFST 2956
C C G++GR+CE K T
Sbjct: 773 QCTCRTGFMGRHCEQKCPSGT 793
Score = 38.9 bits (89), Expect = 0.081
Identities = 25/74 (33%), Positives = 29/74 (39%), Gaps = 6/74 (8%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP--HHCSRGATCISLPHGYT 2676
C NG C S C CT GW G +CT+ D C GA C +
Sbjct: 718 CHNGAFC--SAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHI--SGQ 773
Query: 2677 CFCPLGTTGIYCEQ 2690
C C G G +CEQ
Sbjct: 774 CTCRTGFMGRHCEQ 787
Score = 38.5 bits (88), Expect = 0.11
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 2615 SLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS--RGATCISLP 2672
S +C NG C + + C+C G++G C + +D C GATC +
Sbjct: 150 SRCQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVT 207
Query: 2673 HGYTCFCPLGTTGIYCE 2689
C CP G TG +CE
Sbjct: 208 G--ECRCPPGYTGAFCE 222
Score = 38.5 bits (88), Expect = 0.11
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 13/85 (15%)
Query: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFS 2934
+C+NG +C + T C C P + G C+ ++C + C + ++C P
Sbjct: 414 SCQNGADC--DSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG-- 469
Query: 2935 YSCLCTLGWVGRYCENKTSFSTAKF 2959
SC C GW G C + T F
Sbjct: 470 -SCTCKAGWHGVDCSIRCPSGTWGF 493
Score = 38.1 bits (87), Expect = 0.14
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 7/78 (8%)
Query: 2630 TSVYCNCTTGWKGSFCTETVS--TCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIY 2687
T+ +C C GW G C + P P +C GA+C P C C G G
Sbjct: 553 TTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC--SPDDGICECAPGFRGTT 610
Query: 2688 CEQALSISDPSFRSNELS 2705
C++ I P F + S
Sbjct: 611 CQR---ICSPGFYGHRCS 625
Score = 37.7 bits (86), Expect = 0.18
Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 23/89 (25%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETV------STCDPEHDPPHHCSRGATC---- 2668
C NGG C + C+C +GW G+ C + C E C G TC
Sbjct: 240 CQNGGVCHH--VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQE----CQCHNGGTCDAAT 293
Query: 2669 --ISLPHGYT---C--FCPLGTTGIYCEQ 2690
GYT C CP+GT G+ C +
Sbjct: 294 GQCHCSPGYTGERCQDECPVGTYGVLCAE 322
Score = 36.6 bits (83), Expect = 0.40
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 23/93 (24%)
Query: 2610 HASPCSLM-KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVST----------CDPEHDP 2658
+ C+L+ +C NG C S C C TG+ G C + + CD
Sbjct: 751 YGKDCALICQCQNGADC--DHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD----- 803
Query: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCEQA 2691
C +TC + TC+C G G C+QA
Sbjct: 804 ---CLNNSTCDHITG--TCYCSPGWKGARCDQA 831
Score = 36.2 bits (82), Expect = 0.53
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 9/102 (8%)
Query: 2593 LGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTE--TVS 2650
+G G P G+ + C +C NGGTC + C+C+ G+ G C + V
Sbjct: 260 MGTVCGQPCPEGRFGKNCSQEC---QCHNGGTC--DAATGQCHCSPGYTGERCQDECPVG 314
Query: 2651 TCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQAL 2692
T C G C + C C G G CE L
Sbjct: 315 TYGVLCAETCQCVNGGKCYHV--SGACLCEAGFAGERCEARL 354
Score = 36.2 bits (82), Expect = 0.53
Identities = 29/114 (25%), Positives = 38/114 (33%), Gaps = 29/114 (25%)
Query: 2605 SVGQCHASP--------------------CSLMKCGNGGTCIESGTSVYCNCTTGWKGS- 2643
+ GQCH SP +C NGG C S C C G+ G
Sbjct: 292 ATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYH--VSGACLCEAGFAGER 349
Query: 2644 ----FCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
C E + + P H +C P C C G +G+YC + S
Sbjct: 350 CEARLCPEGLYGIKCDKRCPCHLENTHSCH--PMSGECACKPGWSGLYCNETCS 401
Score = 36.2 bits (82), Expect = 0.53
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 19/77 (24%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTC-----------NQSVSCLNNLCLHQSLCIPDQS 2932
C + C + TT CRCLP W+G C N S+ C C + + C PD
Sbjct: 544 CSHADGC--HPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPC---YCKNGASCSPDDG 598
Query: 2933 FSYSCLCTLGWVGRYCE 2949
C C G+ G C+
Sbjct: 599 I---CECAPGFRGTTCQ 612
Score = 35.8 bits (81), Expect = 0.69
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 13/80 (16%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIP 2929
N DCD + G TCR G G +C G C Q CLNN S C
Sbjct: 763 NGADCDHIS-GQCTCRTG----FMGRHCEQKCPSGTYGYGCRQICDCLNN-----STC-- 810
Query: 2930 DQSFSYSCLCTLGWVGRYCE 2949
+ +C C+ GW G C+
Sbjct: 811 -DHITGTCYCSPGWKGARCD 829
Score = 35.4 bits (80), Expect = 0.90
Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 14/89 (15%)
Query: 2614 CSL-MKCGNGGTCIES-----------GTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH 2661
CSL C NG +C GT+ C+ G+ G C++T C P HH
Sbjct: 581 CSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHH 640
Query: 2662 CSRGATCISLPHGYTC--FCPLGTTGIYC 2688
+ C+ G C CP G G C
Sbjct: 641 ITGLCDCLPGFTGALCNEVCPSGRFGKNC 669
Score = 35.0 bits (79), Expect = 1.2
Identities = 29/104 (27%), Positives = 39/104 (37%), Gaps = 31/104 (29%)
Query: 2867 GGSNVGD-CDGTACGYNT-----CRNGGECTVNGTTFSCRCLPDWAG------------- 2907
GG+N CDG G + C+NG C N T +C C + G
Sbjct: 131 GGTNCSSACDGDHWGPHCTSRCQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYG 188
Query: 2908 NTCNQSVSCLNNL-CLHQSLCIPDQSFSYSCLCTLGWVGRYCEN 2950
N C+Q C N C H + C C G+ G +CE+
Sbjct: 189 NDCHQRCQCQNGATCDH---------VTGECRCPPGYTGAFCED 223
Score = 33.9 bits (76), Expect = 2.6
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 14/77 (18%)
Query: 2888 GECTVNGTTFSCRCLPDWAGNTCNQSVS-------CLNNL-CLHQSLCIPDQSFSYSCLC 2939
G C T C+C P W G C+ + C + C + +LC P + +C C
Sbjct: 116 GRCIAPNT---CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNP---ITGACHC 169
Query: 2940 TLGWVGRYCENKTSFST 2956
G+ G CE++ T
Sbjct: 170 AAGFRGWRCEDRCEQGT 186
Score = 33.9 bits (76), Expect = 2.6
Identities = 21/81 (25%), Positives = 32/81 (39%), Gaps = 13/81 (16%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFSY 2935
C+NGG C + T C C W G C Q +C C + C + +
Sbjct: 240 CQNGGVC--HHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC---DAATG 294
Query: 2936 SCLCTLGWVGRYCENKTSFST 2956
C C+ G+ G C+++ T
Sbjct: 295 QCHCSPGYTGERCQDECPVGT 315
Score = 33.9 bits (76), Expect = 2.6
Identities = 23/79 (29%), Positives = 28/79 (35%), Gaps = 12/79 (15%)
Query: 2884 CRNGGECT-VNGTTFSCRCLPDWAGNTCNQ--------SVSCLNNLCLHQSLCIPDQSFS 2934
C NGG+C V+G +C C +AG C + C H S
Sbjct: 326 CVNGGKCYHVSG---ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMS 382
Query: 2935 YSCLCTLGWVGRYCENKTS 2953
C C GW G YC S
Sbjct: 383 GECACKPGWSGLYCNETCS 401
Score = 33.5 bits (75), Expect = 3.4
Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 25/88 (28%)
Query: 2614 CSLM-KCGNGGTCIE-SGTSVYCNCTTGWKGSFC----------TETVSTCDPEHDPPHH 2661
C+L +C NGG C GT C C GW+G C CD H H
Sbjct: 495 CNLTCQCLNGGACNTLDGT---CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCH 551
Query: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
+ G C C G +G++C+
Sbjct: 552 PTTG----------HCRCLPGWSGVHCD 569
Score = 33.1 bits (74), Expect = 4.4
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 8/41 (19%)
Query: 2103 CQQDV-CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
C Q+ CHNGGTC A + QC C +TG C+ +
Sbjct: 277 CSQECQCHNGGTCDA-------ATGQCHCSPGYTGERCQDE 310
Score = 33.1 bits (74), Expect = 4.4
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 16/94 (17%)
Query: 2860 LTEFGAKGGSNVGDCDGTAC----GYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS 2915
L +G S G + C G TC+ G +G S RC G CN +
Sbjct: 445 LGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGW----HGVDCSIRCPSGTWGFGCNLTCQ 500
Query: 2916 CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
CLN C + +C C GW G CE
Sbjct: 501 CLNG-----GAC---NTLDGTCTCAPGWRGEKCE 526
Score = 32.7 bits (73), Expect = 5.8
Identities = 22/79 (27%), Positives = 28/79 (35%), Gaps = 25/79 (31%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWA-------------GNTCNQSVSCLN-NLCLHQSLCIP 2929
C+NG C + T CRC P + G C Q C N +C H
Sbjct: 197 CQNGATC--DHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHH------ 248
Query: 2930 DQSFSYSCLCTLGWVGRYC 2948
+ C C GW+G C
Sbjct: 249 ---VTGECSCPSGWMGTVC 264
Score = 32.3 bits (72), Expect = 7.6
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 10/73 (13%)
Query: 2874 CDGTACGYNTCRNGGECTVNGT----TFSCRCLPDWAGNTCNQS----VSCLNNLCLHQS 2925
C GY CR +C N T T +C C P W G C+Q+ V LN+L S
Sbjct: 789 CPSGTYGYG-CRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLS-RTS 846
Query: 2926 LCIPDQSFSYSCL 2938
+P S+ +
Sbjct: 847 TALPADSYQIGAI 859
Score = 32.0 bits (71), Expect = 9.9
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 16/76 (21%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP----------CGNGATCVPKSGTD 2393
C+N C + C C + G C+ CE C NGATC +G
Sbjct: 154 CKNGALC--NPITGACHCAAGFRGWRCE-DRCEQGTYGNDCHQRCQCQNGATCDHVTGE- 209
Query: 2394 IVCLCPYGRSGPLCTD 2409
C CP G +G C D
Sbjct: 210 --CRCPPGYTGAFCED 223
Score = 32.0 bits (71), Expect = 9.9
Identities = 18/58 (31%), Positives = 23/58 (39%), Gaps = 11/58 (18%)
Query: 2899 CRCLPDWAGNTCNQ-------SVSCLN-NLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
C CLP + G CN+ +C C + C P SC C GW+G C
Sbjct: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNP---IDRSCQCYPGWIGSDC 699
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 184 bits (466), Expect = 2e-45
Identities = 282/1125 (25%), Positives = 372/1125 (33%), Gaps = 297/1125 (26%)
Query: 222 CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICE 281
C+N G+C+ + C C +TG C+E C P F NCS F C
Sbjct: 527 CRNGGTCLLGLDG-------CDCPEGWTGLICNET---CPPDT-FGKNCS------FSCS 569
Query: 282 CDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYE--CPKGSSSQNGETDVSEFSLV 339
C +G C+ C CP S E CPKG ++ +
Sbjct: 570 CQ---NGGTCDSVTGACR---------CPPGVSGTNCEDGCPKGYYGKHCRKKCN----- 612
Query: 340 PCQNGTDCIKISNDVMCICSP----IFTDLLCK--SIQTSCESFPLRNNATCKKCEK-DY 392
C N C ++ C+C P F L C + C + C+K D
Sbjct: 613 -CANRGRCHRLYG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDG 669
Query: 393 PCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVY 452
CSC +GF + C+ C+L G F C CT
Sbjct: 670 SCSCKAGFRGERCQA---ECEL---------------GYFGPGCWQACT----------- 700
Query: 453 LIHQHLCYCGV---TFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTE 509
C GV + G C + PA F+ GE C F NC+
Sbjct: 701 ------CPVGVACDSVSGECGKRCPAGFQ-----------GEDCGQECPVGTF-GVNCSS 742
Query: 510 DATYVNDP-EDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTT 568
+ P C P T E C E D E R+
Sbjct: 743 SCSCGGAPCHGVTGQCRCPPGRTGEDC--------EADCPEGRW--------------GL 780
Query: 569 DDQE--NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYC-LGNHSISVHGLCLALSH 625
QE CQH A C E C C ++G C D C G + S C
Sbjct: 781 GCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQ---DVCPAGWYGPSCQTRC----- 830
Query: 626 NCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDEC 685
+C G C T C SC G T + R C G G C
Sbjct: 831 SCANDGH-------CHPATGHC---SCAPGWTGFSCQ----RACDTGHWGPDC------- 869
Query: 686 ASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILN----- 740
SHPC A G+ C + CLC GYVG RCEQ
Sbjct: 870 -SHPCNCSA------GHGSCDAISGL-------CLCEAGYVGPRCEQQCPQGHFGPGCEQ 915
Query: 741 --ACEHNSTCKDLHLSYQCVCLSDWEGNFCEQE------SNECKMN-PCKNNSTCTDLYK 791
C+H + C H+S C C + W G FCE +C+ C + C +
Sbjct: 916 RCQCQHGAACD--HVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNG 973
Query: 792 SYRCECTSGWTGQNCSEEI-------NECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQ 844
S C C +G G C+E N + C NG C + GQ C C P + G
Sbjct: 974 S--CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC--DPVHGQ--CHCAPGWMGP 1027
Query: 845 FCHQRYNLCDLLHNPCRNNSTCL---ALVDANQHCICREEFEGKNCEIDVKDCL----FL 897
C Q L + CR++ C + HC C E + G CE K+CL
Sbjct: 1028 SCLQACP-AGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE---KECLPRDVRA 1083
Query: 898 SCQDYGDCED----MVNNFRCICRPGFSGSLCEIEI------NECSSE-PCKNNGTCVDL 946
C+ G C + + RC+C G++G C+ C+ C C +
Sbjct: 1084 GCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHV 1143
Query: 947 TNRFFCNCEPEYHGPFCE-------LDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGI 999
T C C P + G CE + ++ C E + G C CA GY G
Sbjct: 1144 TGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATG-TCSCAAGYHGP 1200
Query: 1000 NCEINLDECLSEP-------CLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNP-C 1051
+C+ P CL+ G C C C +GF GT C P C
Sbjct: 1201 SCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDCNLTCPQGRFGPNC 1258
Query: 1052 LH-------GRCTELINEYPCSCDADGTSTQC-------KIKINDCTSIPCMNEGFCQKS 1097
H C + C C +C + + + C N G C
Sbjct: 1259 THVCGCGQGAACDPVTG--TCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH-- 1314
Query: 1098 AHGFTCICPRGYTGAYCEKSIDNCAEPELNSVI-----CLNGGICVDGPGHTFDCRCLPG 1152
A +C C G+TG +CE + C + C N C G CRC PG
Sbjct: 1315 ASNGSCSCGLGWTGRHCELA---CPPGRYGAACHLECSCHNNSTCEPATG---TCRCGPG 1368
Query: 1153 FSGQFCEININECSSSPCLHGADCE-----------DHINGYVCKCQPGWSGHHCENELE 1201
F GQ CE + C P HGA C+ D I+G C C G+ GH CE
Sbjct: 1369 FYGQACE---HPC--PPGFHGAGCQGLCWCQHGAPCDPISGR-CLCPAGFHGHFCER--G 1420
Query: 1202 CIPNSC---VHELCMENEPGS-------TCLCTPGFMTCSIGLLC 1236
C P S H+ C + + G+ CLC PG + L C
Sbjct: 1421 CEPGSFGEGCHQRC-DCDGGAPCDPVTGLCLCPPGRSGATCNLDC 1464
Score = 181 bits (460), Expect = 8e-45
Identities = 292/1190 (24%), Positives = 411/1190 (34%), Gaps = 263/1190 (22%)
Query: 179 SSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDE 237
S+ C G+C+ CHC P F G CQ ++D C +NG C ++ N
Sbjct: 129 SASLCFHGGRCVP---GSAQPCHCPPGFQGPRCQYDVDECR----THNGGCQHRCVN-TP 180
Query: 238 QAYECVCHPPFT----GKNCSEII------GQCQPHVCFHGNCSNITSNSFICECDEQFS 287
+Y C C P F + C I G CQ H C +T C+C F
Sbjct: 181 GSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHH------CVQLTITRHRCQCRPGFQ 234
Query: 288 ----GPFCEVSAKPCVSLLFWKRGICPNSSSAYT----YECPKGSS-SQNGET--DVSEF 336
G C V PC + + G C + EC G + +G+ DV E
Sbjct: 235 LQEDGRHC-VRRSPCAN----RNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC 289
Query: 337 SLVPCQNGTDCIKISNDVMCICSPIFT----DLLCKSIQ----TSCESFPLRNNATCKKC 388
+ Q C+ C+C + C I+ SCE+ + C
Sbjct: 290 AAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHT 349
Query: 389 EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFL 448
C+C G+ ++ C++ + C + C CT NP +
Sbjct: 350 SAGPLCTCPRGYELDTDQRT----------CIDVDDCAD-----SPCCQQVCTNNPGGY- 393
Query: 449 KNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCT 508
+ CY G ++G C+ V D C
Sbjct: 394 -------ECGCYAGYRL---------------------SADGCGCEDV-DECASSRGGCE 424
Query: 509 EDATYVNDPEDNNSSC---WFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYL- 564
T N SC + HE + GCS L E L F+R ++ +
Sbjct: 425 HHCT--NLAGSFQCSCEAGYRLHEDRR-----GCSPLEEPMVDLDGELPFVRPLPHIAVL 477
Query: 565 -----ENTTDDQENECQHEAVCKDEIN-RPRCSCSLSYIGRLCVVNVDYCLGNHSISVHG 618
+ DD + EA + E + C G C + D C G
Sbjct: 478 QDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG------G 531
Query: 619 LCLALSHNCNC----SGLQRYERNICEIDT--EDCK-SASCKNGTTSTHLRGYFFRKCVP 671
CL C+C +GL E C DT ++C S SC+NG T + G +C P
Sbjct: 532 TCLLGLDGCDCPEGWTGLICNET--CPPDTFGKNCSFSCSCQNGGTCDSVTGAC--RCPP 587
Query: 672 GFKGTQCEIDIDECA----SHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVG 727
G GT CE D C C+ C ++ +C + +CLC+PG G
Sbjct: 588 GVSGTNCE---DGCPKGYYGKHCRKKCNCANRG-----RCHRLYG-----ACLCDPGLYG 634
Query: 728 IRCEQDIDDCILN-ACEHNSTCKDLHLSY------QCVCLSDWEGNFCEQESNECKMNP- 779
C C C H C C + + G C+ E P
Sbjct: 635 RFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPG 694
Query: 780 ------CKNNSTCTDLYKSYRCECTSGWTGQNCSEEIN------ECDSDPCMNGGLCHES 827
C C + C +G+ G++C +E C S G CH
Sbjct: 695 CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV 754
Query: 828 TIPGQFVCLCPPLYTGQFCHQ-----RYNL-CDLLHNPCRNNSTCLALVDANQHCICREE 881
T GQ C CPP TG+ C R+ L C + C++ + C A C+C
Sbjct: 755 T--GQ--CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA---CLCLPG 807
Query: 882 FEGKNCEIDV-------KDC-LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEIN--- 930
F G C+ DV C SC + G C + C C PG++G C+ +
Sbjct: 808 FVGSRCQ-DVCPAGWYGPSCQTRCSCANDGHCHPATGH--CSCAPGWTGFSCQRACDTGH 864
Query: 931 ---ECSSEPCK---NNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISP-----CLDEE 979
+C S PC +G+C ++ C CE Y GP CE + P C +
Sbjct: 865 WGPDC-SHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQH 921
Query: 980 NCVYRTDGYNCLCAPGYTGINCE-------INLDECLSEPCLHDGVCIDGINHYTCDCKS 1032
C C G+ G CE LD C S G D +N +C C +
Sbjct: 922 GAACDHVSGACTCPAGWRGTFCEHACPAGFFGLD-CRSACNCTAGAACDAVNG-SCLCPA 979
Query: 1033 GFFGTHC------ETNANDC-LSNPCLHGRCTELINEYPCSCDADGTSTQC------KIK 1079
G G C T ++C + C +G + ++ C C C +
Sbjct: 980 GRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG-QCHCAPGWMGPSCLQACPAGLY 1038
Query: 1080 INDCT-SIPCMNEGFCQK-SAHGFTCICPRGYTGAYCEKSIDNCAEPEL-----NSVICL 1132
++C S C N G C S H C CP G+ G CEK C ++ +S CL
Sbjct: 1039 GDNCRHSCLCQNGGTCDPVSGH---CACPEGWAGLACEK---ECLPRDVRAGCRHSGGCL 1092
Query: 1133 NGGICVDGPGHTFDCRCLPGFSGQFC----------EININECSSSPCLHGADCEDHING 1182
NGG+C HT C C G++G C E CS P GA C H+ G
Sbjct: 1093 NGGLC---DPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPP---GAACH-HVTG 1145
Query: 1183 YVCKCQPGWSGHHCENELECIPNSCVHELC-MENEPGSTCLCTPGFMTCS 1231
C+C PG++G CE C P S + M PG C P TCS
Sbjct: 1146 -ACRCPPGFTGSGCEQ--ACPPGSFGEDCAQMCQCPGENPACHPATGTCS 1192
Score = 130 bits (328), Expect = 2e-29
Identities = 163/655 (24%), Positives = 227/655 (34%), Gaps = 200/655 (30%)
Query: 684 ECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACE 743
EC++ C +G C+ PG+ C C PG+ G RC+ D+D+C
Sbjct: 127 ECSASLCFHGGRCV--PGS-------------AQPCHCPPGFQGPRCQYDVDEC----RT 167
Query: 744 HNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTG 803
HN C+ C + SY CEC G+
Sbjct: 168 HNGGCQ----------------------------------HRCVNTPGSYLCECKPGFRL 193
Query: 804 QNCSEEINECDSDPCMNGGL---CHESTIPGQFVCLCPPLY----TGQFCHQRYNLCDLL 856
S +S NGG C + TI + C C P + G+ C +R
Sbjct: 194 HTDSRTCLAINSCALGNGGCQHHCVQLTIT-RHRCQCRPGFQLQEDGRHCVRR------- 245
Query: 857 HNPCRN-NSTCL---ALVDANQHCICREEF----EGKNCEIDVKDCLFLSCQDYGDCEDM 908
+PC N N +C+ +V C C + +GK CE DV +C Q C +
Sbjct: 246 -SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECAAGLAQCAHGCLNT 303
Query: 909 VNNFRCICRPGF----SGSLC---EIEI-NECSSEPCKNNGTCVDLTNRFFCNCEPEYHG 960
+F+C+C G+ G C E+EI N C + NNG C C G
Sbjct: 304 QGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEA----NNGGCSH-------GCSHTSAG 352
Query: 961 PFCE--------------LDVNKCKISPCLDEENCVYRTDGYNCLCAPGY----TGINCE 1002
P C +DV+ C SPC ++ C GY C C GY G CE
Sbjct: 353 PLCTCPRGYELDTDQRTCIDVDDCADSPCC-QQVCTNNPGGYECGCYAGYRLSADGCGCE 411
Query: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNP------------ 1050
++DEC S + C + + C C++G + H + L P
Sbjct: 412 -DVDECASSRGGCEHHCTNLAGSFQCSCEAG-YRLHEDRRGCSPLEEPMVDLDGELPFVR 469
Query: 1051 ------CLHGRCTELINEYPCSCD-------ADGTSTQCKIKIND-------CTSIPCMN 1090
L +L + D + T T+ + ++D T C N
Sbjct: 470 PLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRN 529
Query: 1091 EGFCQKSAHGFTCICPRGYTGAYCEKSI--DNCAEPELNSVICLNGGICVDGPGHTFDCR 1148
G C G C CP G+TG C ++ D + S C NGG C G CR
Sbjct: 530 GGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTG---ACR 584
Query: 1149 CLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCV 1208
C PG S G +CED C G+ G HC + C
Sbjct: 585 CPPGVS------------------GTNCED-------GCPKGYYGKHCRKKCNCANRGRC 619
Query: 1209 HELCMENEPGSTCLCTPGF------MTC---SIGLLCGDEIRRITCLTPIFQRTD 1254
H L CLC PG +TC + G C +E + C+ P Q D
Sbjct: 620 HRLY------GACLCDPGLYGRFCHLTCPPWAFGPGCSEECQ---CVQPHTQSCD 665
Score = 123 bits (309), Expect = 3e-27
Identities = 223/963 (23%), Positives = 304/963 (31%), Gaps = 216/963 (22%)
Query: 183 CSGHGKCLSEAWSKTY-SCHCQPPFSGKYCQ-ELDACSFKP-CKNNGSCINKR-ENWDEQ 238
C+ G+C + Y +C C P G++C +F P C C+ ++ D++
Sbjct: 613 CANRGRC-----HRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKR 667
Query: 239 AYECVCHPPFTGKNCSEII-------GQCQPHVCFHGNCSNITSNSFICECDEQFSGPFC 291
C C F G+ C G Q C G + S C F G C
Sbjct: 668 DGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC 727
Query: 292 EVSAKPCVSLLFWKR-------GICPNSSSAYTYECPKGSSSQNGETDVSEF-------S 337
+ C F G P CP G + ++ E D E
Sbjct: 728 ---GQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQE 784
Query: 338 LVP-CQNGTDCIKISNDVMCICSPIFTDLLCKSI----------QTSCESFPLRNNATCK 386
+ P CQ+ C + C+C P F C+ + QT C N+ C
Sbjct: 785 ICPACQHAARCDPETG--ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSC---ANDGHCH 839
Query: 387 KCEKDYPCSCISGFTEKNCEKAID-------------------HCKLLSINCLNEEWCFN 427
CSC G+T +C++A D C +S CL E
Sbjct: 840 PATGH--CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEA---G 894
Query: 428 IIG-RFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFA 486
+G R + C G C + C C HG D A
Sbjct: 895 YVGPRCEQQCPQGHFGPGC----------EQRCQCQ---HGAACDHVSGACTCP-----A 936
Query: 487 GSEGEKCQGVIDAYFF-----LAANCTEDATYVNDPEDNNSSCWFP--HEGTK------- 532
G G C+ A FF A NCT A + N SC P G +
Sbjct: 937 GWRGTFCEHACPAGFFGLDCRSACNCTAGAAC----DAVNGSCLCPAGRRGPRCAETCPA 992
Query: 533 ----EICANGCSCLSEEDSQEYRYLCFLR--WAGNMYLENTTDDQENE-CQHEAVCKD-- 583
C+ C+C + C W G L+ + C+H +C++
Sbjct: 993 HTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGG 1052
Query: 584 --EINRPRCSCSLSYIGRLCVVNV------------DYCLGNHSISVH-GLCLA----LS 624
+ C+C + G C CL H G CL
Sbjct: 1053 TCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG 1112
Query: 625 HNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDI-- 682
C L+ + C + SC G H+ G +C PGF G+ CE
Sbjct: 1113 DKCQSPCLRGWFGEAC------AQRCSCPPGAACHHVTGAC--RCPPGFTGSGCEQACPP 1164
Query: 683 ----DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL--CNPGYVGIRCEQDIDD 736
++CA G P C C + G SC C PG G CEQ
Sbjct: 1165 GSFGEDCAQMCQCPGENPACHPATGTCSCAAGYH---GPSCQQRCPPGRYGPGCEQ---- 1217
Query: 737 CILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP-------CKNNSTCTDL 789
L C + +C + C C + + G C + + P C + C +
Sbjct: 1218 --LCGCLNGGSCDAA--TGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPV 1273
Query: 790 YKSYRCECTSGWTGQNCSEEINE------CDSD-PCMNGGLCHESTIPGQFVCLCPPLYT 842
+ C C G G C + C+ C NGGLCH S C C +T
Sbjct: 1274 TGT--CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS----CSCGLGWT 1327
Query: 843 GQFCHQ-----RYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE------IDV 891
G+ C RY L C NNSTC A C C F G+ CE
Sbjct: 1328 GRHCELACPPGRYGAACHLECSCHNNSTC---EPATGTCRCGPGFYGQACEHPCPPGFHG 1384
Query: 892 KDCLFLS-CQDYGDCEDMVNNFRCICRPGFSGSLCEI-----EINECSSEPCKNNG--TC 943
C L CQ C+ + RC+C GF G CE E + C +G C
Sbjct: 1385 AGCQGLCWCQHGAPCDPISG--RCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPC 1442
Query: 944 VDLTNRFFCNCEPEYHGPFCELDVNKCKISP-CLDEENCVYRTD----GYNCLCAPGYTG 998
+T C C P G C LD + + P C +C D C C GY G
Sbjct: 1443 DPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMG 1500
Query: 999 INC 1001
C
Sbjct: 1501 PTC 1503
Score = 75.9 bits (185), Expect = 6e-13
Identities = 153/690 (22%), Positives = 218/690 (31%), Gaps = 158/690 (22%)
Query: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCH-CQPPFSGKYCQELDACSFKPCKNNGSCINKR 232
CQ + + SG C + W T+ H C F G C+ AC+ C +C
Sbjct: 919 CQHGAACDHVSGACTCPA-GWRGTFCEHACPAGFFGLDCRS--ACN---CTAGAAC---- 968
Query: 233 ENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
D C+C G C+E C H H NCS C C F+G C+
Sbjct: 969 ---DAVNGSCLCPAGRRGPRCAET---CPAHTYGH-NCSQA------CAC---FNGASCD 1012
Query: 293 VSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISN 352
C W C + CP G N CQNG C +S
Sbjct: 1013 PVHGQCHCAPGWMGPSCLQA-------CPAGLYGDNCRHSCL------CQNGGTCDPVSG 1059
Query: 353 DVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKK---------CEKDYP-CSCISGFTE 402
C C + L C+ E P A C+ C+ C C +G+T
Sbjct: 1060 H--CACPEGWAGLACEK-----ECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG 1112
Query: 403 KNCEKA-----IDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCW-------FLKN 450
C+ +C C ++ G + C PG T + C F ++
Sbjct: 1113 DKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACR--CPPGFTGSGCEQACPPGSFGED 1170
Query: 451 VYLIHQ------------HLCYCGVTFHG-ICQDKGPAQFEYVWQLGFAGSEGEKCQGVI 497
+ Q C C +HG CQ + P G G E+ G +
Sbjct: 1171 CAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPP--------GRYGPGCEQLCGCL 1222
Query: 498 DAYFFLAAN--CTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCF 555
+ AA C ++ D N +C P C + C C C
Sbjct: 1223 NGGSCDAATGACRCPTGFLGT--DCNLTC--PQGRFGPNCTHVCGCGQGAACDPVTGTCL 1278
Query: 556 LRWAGNMYLENTTDDQENE----CQHEAVCKD----EINRPRCSCSLSYIGRLCVVNVDY 607
G + +N C+H C++ + CSC L + GR C +
Sbjct: 1279 CP-PGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPP 1337
Query: 608 CLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFR 667
G + + H C+C + + CE T C+ G H
Sbjct: 1338 --GRYGAACH-------LECSC-----HNNSTCEPATGTCRCGPGFYGQACEH------- 1376
Query: 668 KCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL--CNPGY 725
C PGF G C+ C++GA C G C C F G C C PG
Sbjct: 1377 PCPPGFHGAGCQ------GLCWCQHGAPCDPISGR--CLCPAGFH---GHFCERGCEPGS 1425
Query: 726 VGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP------ 779
G C Q D C+ + C + + C+C G C + + P
Sbjct: 1426 FGEGCHQRCD------CDGGAPCDPV--TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHC 1477
Query: 780 -CKNNSTCTDLYKSYRCECTSGWTGQNCSE 808
C + C + S +C C G+ G C E
Sbjct: 1478 DCGGGADCDPV--SGQCHCVDGYMGPTCRE 1505
Score = 66.2 bits (160), Expect = 5e-10
Identities = 40/135 (29%), Positives = 57/135 (42%), Gaps = 15/135 (11%)
Query: 1119 DNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININEC--SSSPCLHGADC 1176
+ C E ++ +C +GG CV PG C C PGF G C+ +++EC + C H C
Sbjct: 121 EGCLSAECSASLCFHGGRCV--PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH--RC 176
Query: 1177 EDHINGYVCKCQPGWSGHHCENELECIPN------SCVHELCMENEPGSTCLCTPGFMTC 1230
+ Y+C+C+PG+ H I + C H C C PGF
Sbjct: 177 VNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQ 236
Query: 1231 SIGLLCGDEIRRITC 1245
G C +RR C
Sbjct: 237 EDGRHC---VRRSPC 248
Score = 50.1 bits (118), Expect = 4e-05
Identities = 153/684 (22%), Positives = 200/684 (29%), Gaps = 174/684 (25%)
Query: 154 SGPSPCPLGLRLNVTVKQQFCQESLSSEF----CSGHGKCLSEAWSKTY--SCHCQPPFS 207
SG CP G R FC+ + + F C C + A SC C
Sbjct: 929 SGACTCPAGWR------GTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRR 982
Query: 208 GKYCQEL-----------DACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSE- 255
G C E AC+ C N SC D +C C P + G +C +
Sbjct: 983 GPRCAETCPAHTYGHNCSQACA---CFNGASC-------DPVHGQCHCAPGWMGPSCLQA 1032
Query: 256 ----IIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKP-CVSLLFWKRGICP 310
+ G H C N S C C E ++G CE P V G C
Sbjct: 1033 CPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCL 1092
Query: 311 NSSSAYTYE----CPKGSSSQN----------GETDVSEFSLVPCQNGTDCIKISNDVMC 356
N + CP G + GE S C G C ++ C
Sbjct: 1093 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS---CPPGAACHHVTG--AC 1147
Query: 357 ICSPIFTDLLCKSIQTSCESFPLRNN-ATCKKCEKDYP--------CSCISGFTEKNCEK 407
C P FT C + +C + A +C + P CSC +G+ +C++
Sbjct: 1148 RCPPGFTGSGC---EQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1204
Query: 408 AI------DHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPC-------WFLKNVYLI 454
C+ L CLN C G + C G C F N
Sbjct: 1205 RCPPGRYGPGCEQL-CGCLNGGSCDAATGACR--CPTGFLGTDCNLTCPQGRFGPNC--- 1258
Query: 455 HQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYV 514
H+C CG G D P + G AG E+ G F + T
Sbjct: 1259 -THVCGCG---QGAACD--PVTGTCLCPPGRAGVRCER--GCPQNRFGVGCEHTCSCRNG 1310
Query: 515 NDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENE 574
+N SC T C C Y C L E
Sbjct: 1311 GLCHASNGSCSCGLGWTGRHCELAC------PPGRYGAACHL---------------ECS 1349
Query: 575 CQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQR 634
C + + C+ C C + G+ C G H GLC H C +
Sbjct: 1350 CHNNSTCEPATG--TCRCGPGFYGQAC--EHPCPPGFHGAGCQGLCWC-QHGAPCDPIS- 1403
Query: 635 YERNICEIDTEDCKSASCKNGTTSTHLRGYFF-RKCVPGFKGTQCEIDIDECASHPCKNG 693
R +C G+F R C PG G C D C G
Sbjct: 1404 -GRCLC-----------------PAGFHGHFCERGCEPGSFGEGCHQRCD------CDGG 1439
Query: 694 ATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDI------DDCILNA-CEHNS 746
A C G CLC PG G C D C L+ C +
Sbjct: 1440 APCDPVTG----------------LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGA 1483
Query: 747 TCKDLHLSYQCVCLSDWEGNFCEQ 770
C +S QC C+ + G C +
Sbjct: 1484 DCDP--VSGQCHCVDGYMGPTCRE 1505
Score = 48.9 bits (115), Expect = 8e-05
Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 14/83 (16%)
Query: 2614 CSLM--KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGA 2666
CSL C NGGTC+ C+C GW G C E TC P+ + C G
Sbjct: 520 CSLTCDDCRNGGTCLLGLDG--CDCPEGWTGLICNE---TCPPDTFGKNCSFSCSCQNGG 574
Query: 2667 TCISLPHGYTCFCPLGTTGIYCE 2689
TC S+ C CP G +G CE
Sbjct: 575 TCDSVTG--ACRCPPGVSGTNCE 595
Score = 46.6 bits (109), Expect = 4e-04
Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 6/73 (8%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH--CSRGATCISLPHGYT 2676
C NGGTC S +C C GW G C + D H C G C PH
Sbjct: 1048 CQNGGTC--DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCD--PHTGR 1103
Query: 2677 CFCPLGTTGIYCE 2689
C CP G TG C+
Sbjct: 1104 CLCPAGWTGDKCQ 1116
Score = 45.8 bits (107), Expect = 7e-04
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 15/79 (18%)
Query: 2339 CAHH-LCRNNGTCISDNENLFCECPRLYSGKLCQF--------ASCENNP-CGNGATCVP 2388
C H LC+N GTC D + C CP ++G C+ A C ++ C NG C P
Sbjct: 1042 CRHSCLCQNGGTC--DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDP 1099
Query: 2389 KSGTDIVCLCPYGRSGPLC 2407
+G CLCP G +G C
Sbjct: 1100 HTGR---CLCPAGWTGDKC 1115
Score = 44.3 bits (103), Expect = 0.002
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
Query: 2609 CHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC 2668
C ++ CS C +GG C+ G++ C+C G++G C V C + H C
Sbjct: 123 CLSAECSASLCFHGGRCV-PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH-----RC 176
Query: 2669 ISLPHGYTCFCPLG 2682
++ P Y C C G
Sbjct: 177 VNTPGSYLCECKPG 190
Score = 44.3 bits (103), Expect = 0.002
Identities = 29/80 (36%), Positives = 38/80 (47%), Gaps = 12/80 (15%)
Query: 2616 LMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCIS 2670
L C NGG+C ++ T C C TG+ G+ C TC P+ C +GA C
Sbjct: 1218 LCGCLNGGSC-DAATGA-CRCPTGFLGTDCN---LTCPQGRFGPNCTHVCGCGQGAACD- 1271
Query: 2671 LPHGYTCFCPLGTTGIYCEQ 2690
P TC CP G G+ CE+
Sbjct: 1272 -PVTGTCLCPPGRAGVRCER 1290
Score = 44.3 bits (103), Expect = 0.002
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 14/73 (19%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENN---------PCGNGATCVPKSGTDI 2394
C N G+C D C CP + G C + CG GA C P +GT
Sbjct: 1221 CLNGGSC--DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT-- 1276
Query: 2395 VCLCPYGRSGPLC 2407
CLCP GR+G C
Sbjct: 1277 -CLCPPGRAGVRC 1288
Score = 43.9 bits (102), Expect = 0.003
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 14/75 (18%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFA--------SCE-NNPCGNGATCVPKSGTDI 2394
CRN GTC+ + C+CP ++G +C +C + C NG TC +G
Sbjct: 527 CRNGGTCLLGLDG--CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTG--- 581
Query: 2395 VCLCPYGRSGPLCTD 2409
C CP G SG C D
Sbjct: 582 ACRCPPGVSGTNCED 596
Score = 43.9 bits (102), Expect = 0.003
Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 14/99 (14%)
Query: 2864 GAKGGSNVGDCDGTACGYN-----TCRNGGECT-VNGTTFSCRCLPDWAGNTCNQS--VS 2915
G +G C G+N C NG C V+G C C P W G +C Q+
Sbjct: 980 GRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG---QCHCAPGWMGPSCLQACPAG 1036
Query: 2916 CLNNLCLHQSLCIPD---QSFSYSCLCTLGWVGRYCENK 2951
+ C H LC S C C GW G CE +
Sbjct: 1037 LYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKE 1075
Score = 43.5 bits (101), Expect = 0.003
Identities = 54/227 (23%), Positives = 83/227 (36%), Gaps = 44/227 (19%)
Query: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPH--VCFHGNCSNIT 274
CS C + G C+ A C C P F G C + +C+ H C H C N T
Sbjct: 128 CSASLCFHGGRCV------PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH-RCVN-T 179
Query: 275 SNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVS 334
S++CEC F ++ C+++ C + + C + + +++
Sbjct: 180 PGSYLCECKPGFR---LHTDSRTCLAI-----NSCALGNGGCQHHCVQLTITRHRCQCRP 231
Query: 335 EFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSC--ESFPLRNNATCKKCEKDY 392
F L ++G C++ S C + SC +R A C +C Y
Sbjct: 232 GFQLQ--EDGRHCVRRSP--------------CANRNGSCMHRCQVVRGLARC-ECHVGY 274
Query: 393 PCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG 439
+ K CE +D C C + C N G FK VC G
Sbjct: 275 QLAA----DGKACED-VDECAAGLAQCAH--GCLNTQGSFKCVCHAG 314
Score = 42.4 bits (98), Expect = 0.007
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 19/78 (24%)
Query: 2884 CRNGGECT-VNGTTFSCRCLPDWAGNTCNQSVSCL----------NNLCLHQSLCIPDQS 2932
C+NGG C V+G C C WAG C + CL + CL+ LC P
Sbjct: 1048 CQNGGTCDPVSG---HCACPEGWAGLACEKE--CLPRDVRAGCRHSGGCLNGGLCDPHTG 1102
Query: 2933 FSYSCLCTLGWVGRYCEN 2950
CLC GW G C++
Sbjct: 1103 ---RCLCPAGWTGDKCQS 1117
Score = 40.0 bits (92), Expect = 0.036
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 5/74 (6%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVST--CDPEHDPPHHCSRGATCISLPHGYT 2676
C N G C + + +C+C GW G C T P+ P +CS G G
Sbjct: 832 CANDGHCHPA--TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG-L 888
Query: 2677 CFCPLGTTGIYCEQ 2690
C C G G CEQ
Sbjct: 889 CLCEAGYVGPRCEQ 902
Score = 40.0 bits (92), Expect = 0.036
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENN----PCGNGATCVPKSGTDIV---C 2396
C++ C D+ + C CP + G C+ A C C + C + D V C
Sbjct: 919 CQHGAAC--DHVSGACTCPAGWRGTFCEHA-CPAGFFGLDCRSACNCTAGAACDAVNGSC 975
Query: 2397 LCPYGRSGPLCTD 2409
LCP GR GP C +
Sbjct: 976 LCPAGRRGPRCAE 988
Score = 39.7 bits (91), Expect = 0.048
Identities = 34/121 (28%), Positives = 45/121 (37%), Gaps = 35/121 (28%)
Query: 2841 PVGFQG--CIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFS 2898
P GFQG C QE + FG S+ C G C +G T
Sbjct: 719 PAGFQGEDC-------GQECPVGTFGVNCSSSCS-CGGAPC-------------HGVTGQ 757
Query: 2899 CRCLPDWAGNTCNQ-------SVSC--LNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
CRC P G C + C + C H + C P+ +CLC G+VG C+
Sbjct: 758 CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETG---ACLCLPGFVGSRCQ 814
Query: 2950 N 2950
+
Sbjct: 815 D 815
Score = 39.7 bits (91), Expect = 0.048
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 16/79 (20%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS-------VSCLNNL-CLHQSLCIPD 2930
CG C G C + T +C C P AG C + V C + C + LC
Sbjct: 1262 CG---CGQGAAC--DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLC--- 1313
Query: 2931 QSFSYSCLCTLGWVGRYCE 2949
+ + SC C LGW GR+CE
Sbjct: 1314 HASNGSCSCGLGWTGRHCE 1332
Score = 39.3 bits (90), Expect = 0.062
Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 8/75 (10%)
Query: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC--LNNLCLHQSLCIPD----QSFSYS 2936
+C N G C + T C C P W G +C ++ C H C + S
Sbjct: 831 SCANDGHC--HPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL 888
Query: 2937 CLCTLGWVGRYCENK 2951
CLC G+VG CE +
Sbjct: 889 CLCEAGYVGPRCEQQ 903
Score = 38.9 bits (89), Expect = 0.081
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 14/85 (16%)
Query: 2873 DCDGTACGYN-TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-------CLNNL-CLH 2923
D G C ++ +C+NGG C + T +CRC P +G C C C +
Sbjct: 558 DTFGKNCSFSCSCQNGGTC--DSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN 615
Query: 2924 QSLCIPDQSFSYSCLCTLGWVGRYC 2948
+ C +CLC G GR+C
Sbjct: 616 RGRC---HRLYGACLCDPGLYGRFC 637
Score = 38.9 bits (89), Expect = 0.081
Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 22/83 (26%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETV----------STCDPEHDPPHHCSRGAT 2667
+C +G C S C C GW+G+FC S C +C+ GA
Sbjct: 918 QCQHGAAC--DHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSAC--------NCTAGAA 967
Query: 2668 CISLPHGYTCFCPLGTTGIYCEQ 2690
C ++ +C CP G G C +
Sbjct: 968 CDAV--NGSCLCPAGRRGPRCAE 988
Score = 38.9 bits (89), Expect = 0.081
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 16/74 (21%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP----------CGNGATCVPKSGTD 2393
C++ C D + C CP + G C+ CE C GA C P +G
Sbjct: 1393 CQHGAPC--DPISGRCLCPAGFHGHFCE-RGCEPGSFGEGCHQRCDCDGGAPCDPVTG-- 1447
Query: 2394 IVCLCPYGRSGPLC 2407
+CLCP GRSG C
Sbjct: 1448 -LCLCPPGRSGATC 1460
Score = 38.5 bits (88), Expect = 0.11
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 15/79 (18%)
Query: 2339 CAHHL-CRNNGTCISDNENLFCECPRLYSGKLCQFA--------SCENN-PCGNGATCVP 2388
C H CRN G C + N + C C ++G+ C+ A +C C N +TC P
Sbjct: 1301 CEHTCSCRNGGLCHASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEP 1358
Query: 2389 KSGTDIVCLCPYGRSGPLC 2407
+GT C C G G C
Sbjct: 1359 ATGT---CRCGPGFYGQAC 1374
Score = 38.1 bits (87), Expect = 0.14
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 6/74 (8%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH--CSRGATCISLPHGYT 2676
C NG +C C+C GW G C + + H C G TC P
Sbjct: 1005 CFNGASC--DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCD--PVSGH 1060
Query: 2677 CFCPLGTTGIYCEQ 2690
C CP G G+ CE+
Sbjct: 1061 CACPEGWAGLACEK 1074
Score = 37.4 bits (85), Expect = 0.24
Identities = 26/83 (31%), Positives = 32/83 (38%), Gaps = 14/83 (16%)
Query: 2876 GTACGYN-TCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSL 2926
G AC +C N C T +CRC P + G C C C H +
Sbjct: 1341 GAACHLECSCHNNSTC--EPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAP 1398
Query: 2927 CIPDQSFSYSCLCTLGWVGRYCE 2949
C P S CLC G+ G +CE
Sbjct: 1399 CDP---ISGRCLCPAGFHGHFCE 1418
Score = 37.0 bits (84), Expect = 0.31
Identities = 41/144 (28%), Positives = 46/144 (31%), Gaps = 54/144 (37%)
Query: 2592 GLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT----- 2646
G+ G P VG H CS C NGG C S S C+C GW G C
Sbjct: 1285 GVRCERGCPQNRFGVGCEHT--CS---CRNGGLCHASNGS--CSCGLGWTGRHCELACPP 1337
Query: 2647 -------------ETVSTCDP----------------EHD--PPHH---------CSRGA 2666
STC+P EH P H C GA
Sbjct: 1338 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGA 1397
Query: 2667 TCISLPHGYTCFCPLGTTGIYCEQ 2690
C P C CP G G +CE+
Sbjct: 1398 PCD--PISGRCLCPAGFHGHFCER 1419
Score = 36.6 bits (83), Expect = 0.40
Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 12/78 (15%)
Query: 2341 HHLCRNNGTCISDNENLFCECPRLYSGKLC-------QFA-SCENN-PCGNGATCVPKSG 2391
H C +G D C CP SG C QF SC + CG GA C P SG
Sbjct: 1431 HQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSG 1490
Query: 2392 TDIVCLCPYGRSGPLCTD 2409
C C G GP C +
Sbjct: 1491 Q---CHCVDGYMGPTCRE 1505
Score = 36.2 bits (82), Expect = 0.53
Identities = 27/82 (32%), Positives = 31/82 (37%), Gaps = 12/82 (14%)
Query: 2615 SLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS---- 2670
S C G C S C C G +G C ET P H H+CS+ C +
Sbjct: 958 SACNCTAGAACDAVNGS--CLCPAGRRGPRCAETC----PAHTYGHNCSQACACFNGASC 1011
Query: 2671 -LPHGYTCFCPLGTTGIYCEQA 2691
HG C C G G C QA
Sbjct: 1012 DPVHG-QCHCAPGWMGPSCLQA 1032
Score = 35.8 bits (81), Expect = 0.69
Identities = 28/86 (32%), Positives = 30/86 (34%), Gaps = 28/86 (32%)
Query: 2619 CGNGGTCIE-----------SGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
C NGG C +G C GW G C + S C GA
Sbjct: 1091 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS-----------CPPGAA 1139
Query: 2668 CISLPHGYT--CFCPLGTTGIYCEQA 2691
C H T C CP G TG CEQA
Sbjct: 1140 C----HHVTGACRCPPGFTGSGCEQA 1161
Score = 35.4 bits (80), Expect = 0.90
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 16/85 (18%)
Query: 2613 PCSLMKCGNG-GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGA 2666
PC+ C G G+C S C C G+ G C + C H P C GA
Sbjct: 872 PCN---CSAGHGSC--DAISGLCLCEAGYVGPRCEQQ---CPQGHFGPGCEQRCQCQHGA 923
Query: 2667 TCISLPHGYTCFCPLGTTGIYCEQA 2691
C + C CP G G +CE A
Sbjct: 924 ACDHVSGA--CTCPAGWRGTFCEHA 946
Score = 34.7 bits (78), Expect = 1.5
Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 22/89 (24%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSC-----------RCLPDWAGNTCNQSVSCLNNLC 2921
DC T + CRNGG C + C C PD G C+ S SC N
Sbjct: 519 DCSLTC---DDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG-- 573
Query: 2922 LHQSLCIPDQSFSYSCLCTLGWVGRYCEN 2950
C S + +C C G G CE+
Sbjct: 574 ---GTC---DSVTGACRCPPGVSGTNCED 596
Score = 34.3 bits (77), Expect = 2.0
Identities = 17/33 (51%), Positives = 19/33 (57%), Gaps = 7/33 (21%)
Query: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
C NGG CHA S+G C C L +TGR CE
Sbjct: 1307 CRNGGLCHA---SNG----SCSCGLGWTGRHCE 1332
Score = 33.5 bits (75), Expect = 3.4
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
Query: 2370 CQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
C A C + C +G CVP G+ C CP G GP C
Sbjct: 123 CLSAECSASLCFHGGRCVP--GSAQPCHCPPGFQGPRC 158
Score = 33.1 bits (74), Expect = 4.4
Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 4/72 (5%)
Query: 2332 ENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPK 2389
E C C+ LC + G C+ + C CP + G CQ+ C + G CV
Sbjct: 121 EGCLSAECSASLCFHGGRCVPGSAQP-CHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNT 179
Query: 2390 SGTDIVCLCPYG 2401
G+ +C C G
Sbjct: 180 PGS-YLCECKPG 190
Score = 33.1 bits (74), Expect = 4.4
Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 14/78 (17%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC----LNNLCLHQSLC---IPDQ 2931
CG C NGG C + T +CRC + G CN ++C C H C
Sbjct: 1219 CG---CLNGGSC--DAATGACRCPTGFLGTDCN--LTCPQGRFGPNCTHVCGCGQGAACD 1271
Query: 2932 SFSYSCLCTLGWVGRYCE 2949
+ +CLC G G CE
Sbjct: 1272 PVTGTCLCPPGRAGVRCE 1289
Score = 32.3 bits (72), Expect = 7.6
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 14/73 (19%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFA--------SCENNP-CGNGATCVPKSGTDI 2394
C N +C D + C C + G C A +C ++ C NG TC P SG
Sbjct: 1005 CFNGASC--DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGH-- 1060
Query: 2395 VCLCPYGRSGPLC 2407
C CP G +G C
Sbjct: 1061 -CACPEGWAGLAC 1072
Score = 32.3 bits (72), Expect = 7.6
Identities = 21/83 (25%), Positives = 33/83 (39%), Gaps = 9/83 (10%)
Query: 2876 GTACGYN-TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV--SCLNNLCLHQSLCIPDQS 2932
G AC +C G C + T +CRC P + G+ C Q+ C C +
Sbjct: 1125 GEACAQRCSCPPGAAC--HHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP 1182
Query: 2933 FSY----SCLCTLGWVGRYCENK 2951
+ +C C G+ G C+ +
Sbjct: 1183 ACHPATGTCSCAAGYHGPSCQQR 1205
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 178 bits (452), Expect = 7e-44
Identities = 185/675 (27%), Positives = 255/675 (37%), Gaps = 176/675 (26%)
Query: 652 CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECA--SH--------PCKNGATCIDQPG 701
C+NG + G C GF+G +CE + CA +H C++GA+C + G
Sbjct: 148 CQNGALCNPITGACV--CAAGFRGWRCE---ELCAPGTHGKGCQLPCQCRHGASCDPRAG 202
Query: 702 NYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDID------DCILNA-CEHNSTCKDLHLS 754
CLC PGY G+ CE+ C L C++ TC H++
Sbjct: 203 E----------------CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCH--HIT 244
Query: 755 YQCVCLSDWEGNFCEQE------SNECKMN-PCKNNSTCTDLYKSYRCECTSGWTGQNCS 807
+C C W G C Q C + PC + C + + +C CT+G+ G C
Sbjct: 245 GECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCD--HVTGQCHCTAGYMGDRCQ 302
Query: 808 EEI----------NECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC-DLL 856
EE CD C NGG C +T C C P Y G C +R LC + L
Sbjct: 303 EECPFGSFGFQCSQHCD---CHNGGQCSPTT----GACECEPGYKGPRCQER--LCPEGL 353
Query: 857 HNP-CRNNSTCLALVDANQH-----CICREEFEGKNCEIDVKDC----------LFLSCQ 900
H P C C A + H C C+ + G +C + C L +CQ
Sbjct: 354 HGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN---ESCPVGYYGDGCQLPCTCQ 410
Query: 901 DYGDCEDMVNNFRCICRPGFSGSLCEIEI------NECSSE-PCKNNGTCVDLTNRFFCN 953
+ DC + C C PGF G +C + CSS C N GTC + C
Sbjct: 411 NGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CT 466
Query: 954 CEPEYHGPFCEL-------DVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLD 1006
C+ + G C L +N + C + C DG +C C PG+ G CE+
Sbjct: 467 CKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAAC-SPIDG-SCSCTPGWLGDTCELPCP 524
Query: 1007 E------CLSE-PCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTEL 1059
+ C C H C H C C +G+ G C++ C GR
Sbjct: 525 DGTFGLNCSEHCDCSHADGCDPVTGH--CCCLAGWTGIRCDST--------CPPGRWGPN 574
Query: 1060 INEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSID 1119
+ CSC+ G+ C + C P CQ+ ICP G+ G
Sbjct: 575 CS-VSCSCENGGS---CSPEDGSCECAPGFRGPLCQR-------ICPPGFYG-------H 616
Query: 1120 NCAEPELNSVICLNGGICVDGPGHTFD--CRCLPGFSGQFC-EININECSSSPCLHGADC 1176
CA+P +C++ P H C CLPGFSG C ++ C C
Sbjct: 617 GCAQP---CPLCVHS----SRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSC 669
Query: 1177 EDH-----INGYVCKCQPGWSGHHCENELECIPN----SCVHELCMEN------EPGSTC 1221
++ I+G C+C PGW G C C P +C H N E G+ C
Sbjct: 670 ANNGTCSPIDG-SCQCFPGWIGKDCSQ--ACPPGFWGPACFHACSCHNGASCSAEDGA-C 725
Query: 1222 LCTPGFMTCSIGLLC 1236
CTPG+ GL C
Sbjct: 726 HCTPGW----TGLFC 736
Score = 173 bits (439), Expect = 2e-42
Identities = 200/792 (25%), Positives = 291/792 (36%), Gaps = 172/792 (21%)
Query: 575 CQHEAVCKDEINRPRCSCSLSYIGRLCVVNVD------YCLGNHSISVHGLCLALSHNCN 628
C E V ++ C C + G C D +C LC ++ C
Sbjct: 103 CTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACV 162
Query: 629 CSGLQRYER--NICEIDT--EDCK-SASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDID 683
C+ R R +C T + C+ C++G + G C PG+ G CE ++
Sbjct: 163 CAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECL--CAPGYTGVYCE-ELC 219
Query: 684 ECASH--------PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL--CNPGYVGIRCEQD 733
SH PC+NG TC G C C P + G C C PG G C QD
Sbjct: 220 PPGSHGAHCELRCPCQNGGTCHHITGE--CACPPGWT---GAVCAQPCPPGTFGQNCSQD 274
Query: 734 IDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESN------ECKMN-PCKNNSTC 786
C H C H++ QC C + + G+ C++E +C + C N C
Sbjct: 275 CP------CHHGGQCD--HVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQC 326
Query: 787 TDLYKSYRCECTSGWTGQNCSEEINE-------------CDSDPCMNGGLCHESTIPGQF 833
+ + CEC G+ G C E + CD+D ++ CH P
Sbjct: 327 SPTTGA--CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTIS---CH----PVTG 377
Query: 834 VCLCPPLYTGQFCHQR-----YNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE 888
C C P ++G C++ Y L C+N + C ++ C C F G+ C
Sbjct: 378 ACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG---CTCAPGFMGEVCA 434
Query: 889 IDVK------DCLFL-SCQDYGDCEDMVNNFRCICRPGFSGSLCEIE-------INECSS 934
+ +C + SC + G C + + C C+ G+ G C + +N S
Sbjct: 435 VSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNES 492
Query: 935 EPCKNNGTCVDLTNRFFCNCEPEYHGPFCELD-------VNKCKISPCLDEENCVYRTDG 987
C N C + C+C P + G CEL +N + C + C T
Sbjct: 493 CTCANGAACSPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG- 549
Query: 988 YNCLCAPGYTGINCEINLDE-------CLSEPCLHDGVC---------IDGINHYTCD-- 1029
+C C G+TGI C+ +S C + G C G C
Sbjct: 550 -HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRI 608
Query: 1030 CKSGFFGTHCETNANDCL--SNPCLH--GRCTELINEYPCSCD---ADGTSTQCKIKIND 1082
C GF+G C C+ S PC H G C L C+ A G Q D
Sbjct: 609 CPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQ------D 662
Query: 1083 CTSI-PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGP 1141
C + C N G C S +C C G+ G C ++ P C + C +G
Sbjct: 663 CAQLCSCANNGTC--SPIDGSCQCFPGWIGKDCSQA----CPPGFWGPACFHACSCHNGA 716
Query: 1142 GHTFD---CRCLPGFSGQFCEINI------NECSS-SPCLHGADCEDHINGYVC------ 1185
+ + C C PG++G FC +C C +GA C DHI+G
Sbjct: 717 SCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC-DHISGKCTCRTGFT 775
Query: 1186 ------KCQPGWSGHHCENELECIPNS-CVHELCMENEPGSTCLCTPGF--MTCSIGLLC 1236
+C PG G+ C+ EC+ NS C H TC C+PGF + C L
Sbjct: 776 GQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVT-------GTCYCSPGFKGIRCDQAALM 828
Query: 1237 GDEIRRITCLTP 1248
+E+ T ++P
Sbjct: 829 MEELNPYTKISP 840
Score = 152 bits (384), Expect = 5e-36
Identities = 236/991 (23%), Positives = 331/991 (33%), Gaps = 277/991 (27%)
Query: 162 GLRLNVTVKQQFCQESLSS-EFCSG-------HGKCLSEAWSKTYSCHCQPPFSGKYCQE 213
GLR + Q C S +FC HG+C+S +CHC+P + G C
Sbjct: 77 GLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPD-----TCHCEPGWGGPDCSS 131
Query: 214 -LDACSFKP-CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271
D+ + P C N C N + CVC F G C E+ C P HG
Sbjct: 132 GCDSDHWGPHCSNRCQCQNGAL-CNPITGACVCAAGFRGWRCEEL---CAPGT--HGKGC 185
Query: 272 NITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYE-CPKGSSSQNGE 330
+ C+C G C+ A C+ P + Y E CP GS + E
Sbjct: 186 QLP-----CQCRH---GASCDPRAGECLC--------APGYTGVYCEELCPPGSHGAHCE 229
Query: 331 TDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSI-------QTSCESFPLRNNA 383
PCQNG C I+ + C C P +T +C Q + P +
Sbjct: 230 LRC------PCQNGGTCHHITGE--CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 281
Query: 384 TCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKN 443
C C C +G+ C+ EE F G F + C C
Sbjct: 282 QCDHVTGQ--CHCTAGYMGDRCQ---------------EECPF---GSFGFQCSQHCD-- 319
Query: 444 PCWFLKNVYLIHQHLCYCGVTFHGICQDK-GPAQFEYVWQLGFAGSEGEKCQGVIDAYFF 502
C+ G G C G + E G +G +CQ +
Sbjct: 320 ---------------CHNG----GQCSPTTGACECE-------PGYKGPRCQERLCPEGL 353
Query: 503 LAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNM 562
CT DN SC H T C+C C + + G+
Sbjct: 354 HGPGCTLPCPC---DADNTISC---HPVT-----GACTCQPGWSGHHCNESCPVGYYGDG 402
Query: 563 YLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLA 622
T CQ+ A C C+C+ ++G +C V+ C A
Sbjct: 403 CQLPCT------CQNGADCHSITGG--CTCAPGFMGEVCAVS---------------CAA 439
Query: 623 LSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDI 682
++ NCS +IC SC NG T + + G C G++G C +
Sbjct: 440 GTYGPNCS-------SIC----------SCNNGGTCSPVDGSC--TCKEGWQGLDCTL-- 478
Query: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCI--LN 740
PC +G ++ + C +DG SC C PG++G CE D LN
Sbjct: 479 ------PCPSGTWGLNCNESCTCANGAACSPIDG-SCSCTPGWLGDTCELPCPDGTFGLN 531
Query: 741 ACEHNSTCKDLH------LSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYR 794
EH C H ++ C CL+ W G C+ + P C S
Sbjct: 532 CSEH---CDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGP-----NC-----SVS 578
Query: 795 CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 854
C C +G + CS E C+ P G LC +CPP + G C Q LC
Sbjct: 579 CSCENGGS---CSPEDGSCECAPGFRGPLCQR---------ICPPGFYGHGCAQPCPLCV 626
Query: 855 LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFL-SCQDYGDCEDMVNNFR 913
PC + S + +C + G +DC L SC + G C + +
Sbjct: 627 HSSRPCHHISGICECLPGFSGALCNQVCAGGYFG---QDCAQLCSCANNGTCSPIDGS-- 681
Query: 914 CICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKIS 973
C C PG+ G +CS C P + GP C + C
Sbjct: 682 CQCFPGWIGK-------DCSQA------------------CPPGFWGPAC---FHACS-- 711
Query: 974 PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECL-SEPCLHDGVCIDGIN--HYT--C 1028
C + +C DG C C PG+TG+ C + C C +G + H + C
Sbjct: 712 -CHNGASCSAE-DGA-CHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKC 768
Query: 1029 DCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCS--CDADGTSTQCKIKINDCTSI 1086
C++GF G HCE RC Y C C+
Sbjct: 769 TCRTGFTGQHCEQ-------------RCAPGTFGYGCQQLCE------------------ 797
Query: 1087 PCMNEGFCQKSAHGFTCICPRGYTGAYCEKS 1117
CMN C TC C G+ G C+++
Sbjct: 798 -CMNNSTCDHVTG--TCYCSPGFKGIRCDQA 825
Score = 109 bits (272), Expect = 5e-23
Identities = 126/498 (25%), Positives = 163/498 (32%), Gaps = 178/498 (35%)
Query: 765 GNFCEQE-SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGL 823
G+FC + EC C + TC C GW G +CS + CDSD
Sbjct: 96 GDFCIPLCTEECVHGRCVSPDTC---------HCEPGWGGPDCS---SGCDSD------- 136
Query: 824 CHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFE 883
+ G C R C+N + C + A C+C F
Sbjct: 137 -----------------HWGPHCSNRCQ--------CQNGALCNPITGA---CVCAAGFR 168
Query: 884 GKNC-EIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGT 942
G C E+ CQ C CR G S C+ EC P
Sbjct: 169 GWRCEELCAPGTHGKGCQ-----------LPCQCRHGAS---CDPRAGECLCAPGYTGVY 214
Query: 943 CVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCE 1002
C +L C P HG CEL +C PC + C + T C C PG+TG C
Sbjct: 215 CEEL-------CPPGSHGAHCEL---RC---PCQNGGTCHHITG--ECACPPGWTGAVC- 258
Query: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELIN 1061
++PC G FG +C + DC PC HG +C +
Sbjct: 259 -------AQPC-----------------PPGTFGQNC---SQDC---PCHHGGQCDHVTG 288
Query: 1062 EYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNC 1121
+ C C A +C+ + CP G G C + D
Sbjct: 289 Q--CHCTAGYMGDRCQEE-------------------------CPFGSFGFQCSQHCD-- 319
Query: 1122 AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC----- 1176
C NGG C G C C PG+ G C+ + C LHG C
Sbjct: 320 ---------CHNGGQCSPTTGA---CECEPGYKGPRCQERL--CPEG--LHGPGCTLPCP 363
Query: 1177 -------EDHINGYVCKCQPGWSGHHCENELEC--------IPNSCVHELCMENEPGSTC 1221
H C CQPGWSGHHC +P +C + + G C
Sbjct: 364 CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG-C 422
Query: 1222 LCTPGFM--TCSIGLLCG 1237
C PGFM C++ G
Sbjct: 423 TCAPGFMGEVCAVSCAAG 440
Score = 63.5 bits (153), Expect = 3e-09
Identities = 87/321 (27%), Positives = 119/321 (37%), Gaps = 65/321 (20%)
Query: 158 PCPLG-LRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDA 216
PCP G LN + + C + + +GH CL+ C P G C +
Sbjct: 522 PCPDGTFGLNCS-EHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV--S 578
Query: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEII-------GQCQP-HVCFHG 268
CS C+N GSC + C C P F G C I G QP +C H
Sbjct: 579 CS---CENGGSC-------SPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHS 628
Query: 269 N--CSNITSNSFICECDEQFSGPFC-EVSA-----KPCVSLLFW-KRGIC-PNSSSAYTY 318
+ C +I+ ICEC FSG C +V A + C L G C P S +
Sbjct: 629 SRPCHHISG---ICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCF 685
Query: 319 ECPKGSSSQN----GETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLC------- 367
G G + F C NG C + D C C+P +T L C
Sbjct: 686 PGWIGKDCSQACPPGFWGPACFHACSCHNGASCS--AEDGACHCTPGWTGLFCTQRCPAA 743
Query: 368 ---KSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAID------HCKLLSIN 418
K C+ +N A+C C+C +GFT ++CE+ C+ L
Sbjct: 744 FFGKDCGRVCQC---QNGASCDHISGK--CTCRTGFTGQHCEQRCAPGTFGYGCQQL-CE 797
Query: 419 CLNEEWCFNIIGRFKYVCIPG 439
C+N C ++ G C PG
Sbjct: 798 CMNNSTCDHVTG--TCYCSPG 816
Score = 47.8 bits (112), Expect = 2e-04
Identities = 37/94 (39%), Positives = 42/94 (44%), Gaps = 15/94 (15%)
Query: 2602 AGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP-- 2659
AG GQ A CS C N GTC S C C GW G C++ C P P
Sbjct: 655 AGGYFGQDCAQLCS---CANNGTCSPIDGS--CQCFPGWIGKDCSQ---ACPPGFWGPAC 706
Query: 2660 -HHCS--RGATCISLPHGYTCFCPLGTTGIYCEQ 2690
H CS GA+C S G C C G TG++C Q
Sbjct: 707 FHACSCHNGASC-SAEDG-ACHCTPGWTGLFCTQ 738
Score = 47.0 bits (110), Expect = 3e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 2883 TCRNGGECT-VNGTTFSCRCLPDWAGNTCNQSV--SCLNNLCLHQSLCIPDQSFSY---S 2936
+C N G C+ ++G SC+C P W G C+Q+ C H C S S +
Sbjct: 668 SCANNGTCSPIDG---SCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGA 724
Query: 2937 CLCTLGWVGRYCENK 2951
C CT GW G +C +
Sbjct: 725 CHCTPGWTGLFCTQR 739
Score = 47.0 bits (110), Expect = 3e-04
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 6/74 (8%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH--HCSRGATCISLPHGYT 2676
C NG +C S C+CT GW G FCT+ D C GA+C +
Sbjct: 712 CHNGASC--SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHI--SGK 767
Query: 2677 CFCPLGTTGIYCEQ 2690
C C G TG +CEQ
Sbjct: 768 CTCRTGFTGQHCEQ 781
Score = 43.9 bits (102), Expect = 0.003
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 2598 GHPNAGRSVGQCHASP-CS-LMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS--TCD 2653
G P+ H P CS +C NG C + + C C G++G C E + T
Sbjct: 125 GGPDCSSGCDSDHWGPHCSNRCQCQNGALC--NPITGACVCAAGFRGWRCEELCAPGTHG 182
Query: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690
P C GA+C P C C G TG+YCE+
Sbjct: 183 KGCQLPCQCRHGASCD--PRAGECLCAPGYTGVYCEE 217
Score = 43.9 bits (102), Expect = 0.003
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 15/77 (19%)
Query: 2883 TCRNGGECT-VNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSF 2933
TC NG C+ ++G SC C P W G+TC ++C + C H C P
Sbjct: 494 TCANGAACSPIDG---SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDP---V 547
Query: 2934 SYSCLCTLGWVGRYCEN 2950
+ C C GW G C++
Sbjct: 548 TGHCCCLAGWTGIRCDS 564
Score = 43.1 bits (100), Expect = 0.004
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 13/73 (17%)
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPHGYTC 2677
G C+ T C+C GW G C+ S CD +H PH C GA C P C
Sbjct: 110 GRCVSPDT---CHCEPGWGGPDCS---SGCDSDHWGPHCSNRCQCQNGALC--NPITGAC 161
Query: 2678 FCPLGTTGIYCEQ 2690
C G G CE+
Sbjct: 162 VCAAGFRGWRCEE 174
Score = 42.4 bits (98), Expect = 0.007
Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 15/89 (16%)
Query: 2615 SLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETV--STCDPEHDPPHHCSRGATCISLP 2672
S+ C NGGTC S C C GW+G CT T + C+ GA C +
Sbjct: 448 SICSCNNGGTC--SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPID 505
Query: 2673 HGYTCF-----------CPLGTTGIYCEQ 2690
+C CP GT G+ C +
Sbjct: 506 GSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
Score = 41.6 bits (96), Expect = 0.013
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFSY 2935
C+NGG C + T C C P W G C Q +C + C H C +
Sbjct: 234 CQNGGTC--HHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC---DHVTG 288
Query: 2936 SCLCTLGWVGRYCENKTSFSTAKF 2959
C CT G++G C+ + F + F
Sbjct: 289 QCHCTAGYMGDRCQEECPFGSFGF 312
Score = 41.6 bits (96), Expect = 0.013
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 20/95 (21%)
Query: 2863 FGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL-- 2920
FG+ G CD C NGG+C+ TT +C C P + G C + + C L
Sbjct: 307 FGSFGFQCSQHCD--------CHNGGQCSP--TTGACECEPGYKGPRCQERL-CPEGLHG 355
Query: 2921 --CLHQSLCIPDQSFSY-----SCLCTLGWVGRYC 2948
C C D + S +C C GW G +C
Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC 390
Score = 40.4 bits (93), Expect = 0.028
Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 10/88 (11%)
Query: 2876 GTACGYN-TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC------LNNLCLHQSLCI 2928
G AC + +C NG C+ +C C P W G C Q +C Q+
Sbjct: 703 GPACFHACSCHNGASCSAEDG--ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGAS 760
Query: 2929 PDQSFSYSCLCTLGWVGRYCENKTSFST 2956
D S C C G+ G++CE + + T
Sbjct: 761 CDH-ISGKCTCRTGFTGQHCEQRCAPGT 787
Score = 38.9 bits (89), Expect = 0.081
Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 11/82 (13%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE--HDP----PHHCSRGATCISLP 2672
C NGG C S T+ C C G+KG C E + PE H P P C T P
Sbjct: 320 CHNGGQC--SPTTGACECEPGYKGPRCQERLC---PEGLHGPGCTLPCPCDADNTISCHP 374
Query: 2673 HGYTCFCPLGTTGIYCEQALSI 2694
C C G +G +C ++ +
Sbjct: 375 VTGACTCQPGWSGHHCNESCPV 396
Score = 38.1 bits (87), Expect = 0.14
Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 17/76 (22%)
Query: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL----------CLHQSLCIPDQS 2932
TC+NG +C + T C C P + G C +VSC C + C P
Sbjct: 408 TCQNGADC--HSITGGCTCAPGFMGEVC--AVSCAAGTYGPNCSSICSCNNGGTCSPVDG 463
Query: 2933 FSYSCLCTLGWVGRYC 2948
SC C GW G C
Sbjct: 464 ---SCTCKEGWQGLDC 476
Score = 37.7 bits (86), Expect = 0.18
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 17/102 (16%)
Query: 2610 HASPCSLM-KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP-------EHDPPHH 2661
H + C L C NGGTC + C C GW G+ C + C P D P
Sbjct: 224 HGAHCELRCPCQNGGTCHH--ITGECACPPGWTGAVCAQ---PCPPGTFGQNCSQDCP-- 276
Query: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNE 2703
C G C + C C G G C++ F+ ++
Sbjct: 277 CHHGGQCDHVTG--QCHCTAGYMGDRCQEECPFGSFGFQCSQ 316
Score = 37.7 bits (86), Expect = 0.18
Identities = 27/99 (27%), Positives = 39/99 (39%), Gaps = 22/99 (22%)
Query: 2613 PCSLMKCGNGGTC--IESGTSVYCNCTTGWKGSFCTETVS--TCDPEHDPPHHCSRGATC 2668
PC+ C NG C I G C C G+ G C + + T P C+ G TC
Sbjct: 406 PCT---CQNGADCHSITGG----CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC 458
Query: 2669 ISLPHGYTCF-----------CPLGTTGIYCEQALSISD 2696
+ TC CP GT G+ C ++ + ++
Sbjct: 459 SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCAN 497
Score = 37.7 bits (86), Expect = 0.18
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS--TCDPEHDPPHHCSRGATCISLPHGY 2675
+C NG +C S C C TG+ G C + + T C +TC +
Sbjct: 754 QCQNGASC--DHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTG-- 809
Query: 2676 TCFCPLGTTGIYCEQA 2691
TC+C G GI C+QA
Sbjct: 810 TCYCSPGFKGIRCDQA 825
Score = 36.2 bits (82), Expect = 0.53
Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 14/101 (13%)
Query: 2610 HASPCSL-MKCGNGGTCIESGTSVYCNCTTGWKGSFCTET--VSTCDPEHDPPHHCSRGA 2666
H C+L C T + C C GW G C E+ V P C GA
Sbjct: 354 HGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGA 413
Query: 2667 TCISLPHGYTC-----------FCPLGTTGIYCEQALSISD 2696
C S+ G TC C GT G C S ++
Sbjct: 414 DCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNN 454
Score = 35.0 bits (79), Expect = 1.2
Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 11/58 (18%)
Query: 2899 CRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
C CLP ++G CNQ C C + C P SC C GW+G+ C
Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSP---IDGSCQCFPGWIGKDC 693
Score = 34.7 bits (78), Expect = 1.5
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 13/74 (17%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-------C-LNNLCLHQSLCIPDQSFSY 2935
C+NG C N T +C C + G C + + C L C H + C P
Sbjct: 148 CQNGALC--NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAG--- 202
Query: 2936 SCLCTLGWVGRYCE 2949
CLC G+ G YCE
Sbjct: 203 ECLCAPGYTGVYCE 216
Score = 34.7 bits (78), Expect = 1.5
Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 18/85 (21%)
Query: 2339 CAHHL-CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGAT------------ 2385
C+ H C N G C CEC Y G CQ C G G T
Sbjct: 314 CSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTIS 371
Query: 2386 CVPKSGTDIVCLCPYGRSGPLCTDA 2410
C P +G C C G SG C ++
Sbjct: 372 CHPVTG---ACTCQPGWSGHHCNES 393
Score = 34.7 bits (78), Expect = 1.5
Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 10/75 (13%)
Query: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL----PHG 2674
C NG C S C+CT GW G C P+ +CS C P
Sbjct: 495 CANGAACSPIDGS--CSCTPGWLGDTCELPC----PDGTFGLNCSEHCDCSHADGCDPVT 548
Query: 2675 YTCFCPLGTTGIYCE 2689
C C G TGI C+
Sbjct: 549 GHCCCLAGWTGIRCD 563
Score = 34.3 bits (77), Expect = 2.0
Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 5/70 (7%)
Query: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQS--VSCLNNLCLHQSLC---IPDQSFSYSCL 2938
C + + T +C C P W+G+ CN+S V + C C S + C
Sbjct: 364 CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCT 423
Query: 2939 CTLGWVGRYC 2948
C G++G C
Sbjct: 424 CAPGFMGEVC 433
Score = 34.3 bits (77), Expect = 2.0
Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 2633 YCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPHGYTCFCPLGTTGIY 2687
+C C GW G C STC P P+ C G +C P +C C G G
Sbjct: 550 HCCCLAGWTGIRCD---STCPPGRWGPNCSVSCSCENGGSC--SPEDGSCECAPGFRGPL 604
Query: 2688 CEQALSISDPSF 2699
C++ I P F
Sbjct: 605 CQR---ICPPGF 613
Score = 33.9 bits (76), Expect = 2.6
Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 17/107 (15%)
Query: 2603 GRSVGQCHASPCSLMKCGNGGTCIESGTSVYCN-----------CTTGWKGSFCTETVST 2651
GR C S CS C NGG+C S C C G+ G C +
Sbjct: 569 GRWGPNCSVS-CS---CENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPL 624
Query: 2652 CDPEHDPPHHCSRGATCISLPHGYTC--FCPLGTTGIYCEQALSISD 2696
C P HH S C+ G C C G G C Q S ++
Sbjct: 625 CVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCAN 671
Score = 33.5 bits (75), Expect = 3.4
Identities = 24/86 (27%), Positives = 32/86 (37%), Gaps = 18/86 (20%)
Query: 2332 ENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENN---------PCGN 2382
+ C +P C C+N C S C C + G++C + C N
Sbjct: 401 DGCQLP-CT---CQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNN 454
Query: 2383 GATCVPKSGTDIVCLCPYGRSGPLCT 2408
G TC P G+ C C G G CT
Sbjct: 455 GGTCSPVDGS---CTCKEGWQGLDCT 477
Score = 33.5 bits (75), Expect = 3.4
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 12/73 (16%)
Query: 2350 CISDNENLFCE--CPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
C++ + C+ CP G C SC C NG +C P+ G+ C C G GPLC
Sbjct: 553 CLAGWTGIRCDSTCPPGRWGPNCS-VSCS---CENGGSCSPEDGS---CECAPGFRGPLC 605
Query: 2408 TDAINITQPRFSG 2420
I P F G
Sbjct: 606 Q---RICPPGFYG 615
Score = 33.1 bits (74), Expect = 4.4
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 13/75 (17%)
Query: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLN--NLCLHQSLCIPDQSF 2933
+C NGG C+ SC C P + G C + C LC+H S P
Sbjct: 580 SCENGGSCSPEDG--SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSR--PCHHI 635
Query: 2934 SYSCLCTLGWVGRYC 2948
S C C G+ G C
Sbjct: 636 SGICECLPGFSGALC 650
Score = 33.1 bits (74), Expect = 4.4
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 13/80 (16%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIP 2929
N CD + G TCR G G RC P G C Q C+NN S C
Sbjct: 757 NGASCDHIS-GKCTCRTG----FTGQHCEQRCAPGTFGYGCQQLCECMNN-----STC-- 804
Query: 2930 DQSFSYSCLCTLGWVGRYCE 2949
+ +C C+ G+ G C+
Sbjct: 805 -DHVTGTCYCSPGFKGIRCD 823
Score = 32.7 bits (73), Expect = 5.8
Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 11/60 (18%)
Query: 2898 SCRCLPDWAGNTCNQSVS-------CLNNL-CLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+C C P W G C+ C N C + +LC P + +C+C G+ G CE
Sbjct: 117 TCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNP---ITGACVCAAGFRGWRCE 173
Score = 32.7 bits (73), Expect = 5.8
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 14/73 (19%)
Query: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFA--------SC-ENNPCGNGATCVPKSGTDI 2394
C N GTC + + C C + G C +C E+ C NGA C P G+
Sbjct: 452 CNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGS-- 507
Query: 2395 VCLCPYGRSGPLC 2407
C C G G C
Sbjct: 508 -CSCTPGWLGDTC 519
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 175 bits (444), Expect = 6e-43
Identities = 103/333 (30%), Positives = 144/333 (43%), Gaps = 44/333 (13%)
Query: 795 CECTSGWTGQNCSEEINECDSDPCMNGGLCHES---TIPGQ-FVCLCPPLYTGQFCHQRY 850
C+C W E E C G + T P + F C P +
Sbjct: 863 CDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGP---VDVNILAKC 919
Query: 851 NLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDC---ED 907
N C L NPC+N+ TC + C C F+G++C++ + C+ C+ G C E
Sbjct: 920 NPC--LSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEG 977
Query: 908 MVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDV 967
+ F CIC GF G CE+ +++C C+NN TCVD N + C C PEY G CE +
Sbjct: 978 EEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKL 1037
Query: 968 NKCK--ISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH 1025
+ C ++PC + C+ G+ C C PGY G +C+I+ D+C C + C D +N
Sbjct: 1038 DFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNG 1097
Query: 1026 YTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTS 1085
YTC C G+ G CE S P + R + PC QC ++I
Sbjct: 1098 YTCICPEGYSGLFCE------FSPPMVLPRTS------PCDNFDCQNGAQCIVRI----- 1140
Query: 1086 IPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
NE CQ C GY G CEK +
Sbjct: 1141 ----NEPICQ---------CLPGYQGEKCEKLV 1160
Score = 171 bits (433), Expect = 1e-41
Identities = 85/252 (33%), Positives = 135/252 (53%), Gaps = 26/252 (10%)
Query: 647 CKSASCKN-GTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFC 705
C S CKN GT ++ ++ C GFKG C++ I C S+PCK+G TC + G
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEE-- 979
Query: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEG 765
DGF C+C G+ G CE ++DDC N CE+NSTC D +Y C+C ++ G
Sbjct: 980 ---------DGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTG 1030
Query: 766 NFCEQESNEC--KMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGL 823
CE++ + C +NPC+++S C K ++C+CT G+ G++C + ++C + C NG
Sbjct: 1031 ELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAH 1090
Query: 824 CHESTIPGQFVCLCPPLYTGQFCH-------QRYNLCDLLHNPCRNNSTCLALVDANQHC 876
C ++ + C+CP Y+G FC R + CD + C+N + C+ ++ C
Sbjct: 1091 CTDAV--NGYTCICPEGYSGLFCEFSPPMVLPRTSPCD--NFDCQNGAQCIVRIN-EPIC 1145
Query: 877 ICREEFEGKNCE 888
C ++G+ CE
Sbjct: 1146 QCLPGYQGEKCE 1157
Score = 166 bits (421), Expect = 3e-40
Identities = 87/242 (35%), Positives = 117/242 (48%), Gaps = 16/242 (6%)
Query: 773 NECKMNPCKNNSTC-TDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCH--ESTI 829
N C NPCKN+ TC +D YRC C G+ GQ+C I+ C S+PC +GG CH E
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEE 979
Query: 830 PGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEI 889
G F C+C + G+ C + C+ N C NNSTC+ ++ N C+C E+ G+ CE
Sbjct: 980 DG-FWCICADGFEGENCEVNVDDCE--DNDCENNSTCVDGIN-NYTCLCPPEYTGELCEE 1035
Query: 890 DVKDCL--FLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLT 947
+ C CQ C F+C C PG+ G C+I+ ++C CKN C D
Sbjct: 1036 KLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAV 1095
Query: 948 NRFFCNCEPEYHGPFCELD-------VNKCKISPCLDEENCVYRTDGYNCLCAPGYTGIN 1000
N + C C Y G FCE + C C + C+ R + C C PGY G
Sbjct: 1096 NGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEK 1155
Query: 1001 CE 1002
CE
Sbjct: 1156 CE 1157
Score = 166 bits (420), Expect = 3e-40
Identities = 80/259 (30%), Positives = 124/259 (47%), Gaps = 17/259 (6%)
Query: 717 FSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLS-YQCVCLSDWEGNFCEQESNEC 775
F+C G V + + C+ N C+++ TC + Y+C C ++G C+ + C
Sbjct: 905 FTC---QGPVDVNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHAC 961
Query: 776 KMNPCKNNSTC---TDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQ 832
NPCK+ TC + C C G+ G+NC +++C+ + C N C +
Sbjct: 962 ISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGI--NN 1019
Query: 833 FVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVK 892
+ CLCPP YTG+ C ++ + C NPC+++S C+ L C C + G++C+ID
Sbjct: 1020 YTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCI-LTPKGFKCDCTPGYVGEHCDIDFD 1078
Query: 893 DCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIE-------INECSSEPCKNNGTCVD 945
DC C++ C D VN + CIC G+SG CE + C + C+N C+
Sbjct: 1079 DCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIV 1138
Query: 946 LTNRFFCNCEPEYHGPFCE 964
N C C P Y G CE
Sbjct: 1139 RINEPICQCLPGYQGEKCE 1157
Score = 166 bits (419), Expect = 4e-40
Identities = 104/351 (29%), Positives = 155/351 (44%), Gaps = 43/351 (12%)
Query: 910 NNFRCICRPGFSG----SLCEIEINECSSEPCKNNGTCVDLT---------NRFFCNCEP 956
N RCI F G L + N+ S P G DL+ N +C+C
Sbjct: 811 NRLRCIPPRTFDGLKSLRLLSLHGNDISVVP---EGAFNDLSALSHLAIGANPLYCDCNM 867
Query: 957 EYHGPFCELDVNKCKISPCLDE----ENCVYRTDGYNCLCAPGYTGINCEINLDECLSEP 1012
++ + + + + I+ C + + T C G +N + CLS P
Sbjct: 868 QWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQ-GPVDVNILAKCNPCLSNP 926
Query: 1013 CLHDGVC-IDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELI----NEYPCSC 1067
C +DG C D ++ Y C C GF G C+ + C+SNPC HG L + + C C
Sbjct: 927 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCIC 986
Query: 1068 DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELN 1127
C++ ++DC C N C + +TC+CP YTG CE+ +D CA+ +LN
Sbjct: 987 ADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ-DLN 1045
Query: 1128 SVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKC 1187
C + C+ P F C C PG+ G+ C+I+ ++C + C +GA C D +NGY C C
Sbjct: 1046 P--CQHDSKCILTP-KGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCIC 1102
Query: 1188 QPGWSGHHCENELECI---PNSCVHELCME--------NEPGSTCLCTPGF 1227
G+SG CE + + C + C NEP C C PG+
Sbjct: 1103 PEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEP--ICQCLPGY 1151
Score = 160 bits (405), Expect = 2e-38
Identities = 90/284 (31%), Positives = 125/284 (44%), Gaps = 62/284 (21%)
Query: 930 NECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYN 989
N C S PCKN+GTC N +P D Y
Sbjct: 920 NPCLSNPCKNDGTC---------NSDP----------------------------VDFYR 942
Query: 990 CLCAPGYTGINCEINLDECLSEPCLHDGVCI------DGINHYTCDCKSGFFGTHCETNA 1043
C C G+ G +C++ + C+S PC H G C DG + C C GF G +CE N
Sbjct: 943 CTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDG---FWCICADGFEGENCEVNV 999
Query: 1044 NDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTSI--PCMNEGFCQKSAHG 1100
+DC N C + C + IN Y C C + T C+ K++ C PC ++ C + G
Sbjct: 1000 DDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKG 1059
Query: 1101 FTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEI 1160
F C C GY G +C+ D+C + + C NG C D + + C C G+SG FCE
Sbjct: 1060 FKCDCTPGYVGEHCDIDFDDCQDNK-----CKNGAHCTDAV-NGYTCICPEGYSGLFCEF 1113
Query: 1161 N-------INECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCE 1197
+ + C + C +GA C IN +C+C PG+ G CE
Sbjct: 1114 SPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1157
Score = 129 bits (323), Expect = 6e-29
Identities = 98/348 (28%), Positives = 149/348 (42%), Gaps = 28/348 (8%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH--CSRGATCISL 2671
C KC NG C ++ C C G+ G FC + P P + C GA CI
Sbjct: 1080 CQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVR 1139
Query: 2672 PHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADG 2731
+ C C G G CE+ +S++ N+ S++ S VR +T+I LQ G
Sbjct: 1140 INEPICQCLPGYQGEKCEKLVSVNF----INKESYLQIPSAKVRPQTNITLQIATDEDSG 1195
Query: 2732 ILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKV-TINGSTWHIIKAGR 2790
IL Y D + + L V+ Y+ G + V TIN +HI++
Sbjct: 1196 ILLYKGDK------DHIAVELYRGRVRASYDTGSHPA--SAIYSVETINDGNFHIVELLA 1247
Query: 2791 VGAEGYLDLDGINVTEKAS-TKMSSLDTNTDFYIGGVSSLNLVNPM--AIENEPVGFQGC 2847
+ L +DG N + +K S+L+ ++ Y+GG+ + V + A F GC
Sbjct: 1248 LDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGC 1307
Query: 2848 IRQVIINNQELQLTEFGAKGGSNVG--DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDW 2905
IR + IN++ + + G G C C + TC+ + F+C C W
Sbjct: 1308 IRNLYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGTCQPSSQAG-----FTCECQEGW 1362
Query: 2906 AGNTCNQSVS--CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENK 2951
G C+Q + CL N C+H C+P +FSYSC C G G C+ +
Sbjct: 1363 MGPLCDQRTNDPCLGNKCVH-GTCLPINAFSYSCKCLEGHGGVLCDEE 1409
Score = 123 bits (308), Expect = 3e-27
Identities = 63/223 (28%), Positives = 96/223 (43%), Gaps = 38/223 (17%)
Query: 625 HNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGY---FFRKCVPGFKGTQCEID 681
+ C C ++ C++ C S CK+G T G F+ C GF+G CE++
Sbjct: 941 YRCTCP--YGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVN 998
Query: 682 IDECASHPCKNGATCIDQPGNYFCQCVPPFK--------------------------VVD 715
+D+C + C+N +TC+D NY C C P +
Sbjct: 999 VDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPK 1058
Query: 716 GFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCE------ 769
GF C C PGYVG C+ D DDC N C++ + C D Y C+C + G FCE
Sbjct: 1059 GFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMV 1118
Query: 770 -QESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEIN 811
++ C C+N + C C+C G+ G+ C + ++
Sbjct: 1119 LPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVS 1161
Score = 116 bits (290), Expect = 4e-25
Identities = 64/191 (33%), Positives = 87/191 (45%), Gaps = 26/191 (13%)
Query: 1079 KINDCTSIPCMNEGFCQKSAHGF-TCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGIC 1137
K N C S PC N+G C F C CP G+ G C+ I C S C +GG C
Sbjct: 918 KCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACI-----SNPCKHGGTC 972
Query: 1138 --VDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHH 1195
+G F C C GF G+ CE+N+++C + C + + C D IN Y C C P ++G
Sbjct: 973 HLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGEL 1032
Query: 1196 CENELECIP---NSCVHEL-CMENEPGSTCLCTPGFM--------------TCSIGLLCG 1237
CE +L+ N C H+ C+ G C CTPG++ C G C
Sbjct: 1033 CEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCT 1092
Query: 1238 DEIRRITCLTP 1248
D + TC+ P
Sbjct: 1093 DAVNGYTCICP 1103
Score = 108 bits (269), Expect = 1e-22
Identities = 71/275 (25%), Positives = 117/275 (42%), Gaps = 23/275 (8%)
Query: 159 CPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDAC 217
C + +N+ K C LS+ C G C S+ Y C C F G+ C + AC
Sbjct: 907 CQGPVDVNILAK---CNPCLSNP-CKNDGTCNSDPVD-FYRCTCPYGFKGQDCDVPIHAC 961
Query: 218 SFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNS 277
PCK+ G+C K +E + C+C F G+NC + C+ + C + + N+
Sbjct: 962 ISNPCKHGGTCHLKEG--EEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINN 1019
Query: 278 FICECDEQFSGPFCEVSAKPCVSLL--FWKRGICPNSSSAYTYECPKGSSSQNGETDVSE 335
+ C C +++G CE C L C + + +C G ++ + D +
Sbjct: 1020 YTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDD 1079
Query: 336 FSLVPCQNGTDCIKISNDVMCICSPIFTDLLCK-------SIQTSCESFPLRNNATCKKC 388
C+NG C N CIC ++ L C+ + C++F +N A C
Sbjct: 1080 CQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVR 1139
Query: 389 EKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEE 423
+ C C+ G+ + CE KL+S+N +N+E
Sbjct: 1140 INEPICQCLPGYQGEKCE------KLVSVNFINKE 1168
Score = 106 bits (265), Expect = 3e-22
Identities = 73/274 (26%), Positives = 105/274 (38%), Gaps = 40/274 (14%)
Query: 493 CQGVIDAYFFLAAN------CTEDATYVNDPED----------NNSSCWFP-HEGTKEIC 535
CQG +D N C D T +DP D C P H C
Sbjct: 907 CQGPVDVNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPC 966
Query: 536 ANGCSC-LSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
+G +C L E + + +C + G N D ++N+C++ + C D IN C C
Sbjct: 967 KHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPP 1026
Query: 595 SYIGRLCVVNVDYCLGNHSISVH-GLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCK 653
Y G LC +D+C + + H C+ C Y C+ID +DC+ CK
Sbjct: 1027 EYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCK 1086
Query: 654 NGTTSTHLRGYFFRKCVPGFKGTQCEID-------IDECASHPCKNGATCIDQPGNYFCQ 706
NG T + C G+ G CE C + C+NGA CI + CQ
Sbjct: 1087 NGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQ 1146
Query: 707 CVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILN 740
C+ PGY G +CE+ + +N
Sbjct: 1147 CL--------------PGYQGEKCEKLVSVNFIN 1166
Score = 99.8 bits (247), Expect = 4e-20
Identities = 97/383 (25%), Positives = 149/383 (38%), Gaps = 55/383 (14%)
Query: 2332 ENCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF---------ASCENNPC 2380
E+C + + C + C+N C C CP YSG C+F + C+N C
Sbjct: 1071 EHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDC 1130
Query: 2381 GNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISF 2440
NGA C+ + + +C C G G C +++ + + +Y +I
Sbjct: 1131 QNGAQCIVRI-NEPICQCLPGYQGEKCEKLVSV-----------NFINKESYLQIPSAKV 1178
Query: 2441 HYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASI 2500
+ ++ Q+A + + ++ + G K H +AV L G V SY+ GS AS
Sbjct: 1179 RPQTNITLQIATDE---DSGILLYKGDKDH-------IAVELYRGRVRASYDTGSHPASA 1228
Query: 2501 RSEPLNLSLG-VHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYT 2559
++ G H V L Q L VD K I + LN S YVGG +
Sbjct: 1229 IYSVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKS 1288
Query: 2560 PDLLPNGADFKNG--FQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLM 2617
A +NG F GCI L + +E L + + P + C PC
Sbjct: 1289 NVASLRQAPGQNGTSFHGCIRNLYINSE-------LQDFQKVPMQTGILPGC--EPCHKK 1339
Query: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDP--PHHCSRGATCISL-PHG 2674
C +G S C C GW G C + +DP + C G TC+ +
Sbjct: 1340 VCAHGTCQPSSQAGFTCECQEGWMGPLCDQRT------NDPCLGNKCVHG-TCLPINAFS 1392
Query: 2675 YTCFCPLGTTGIYCEQALSISDP 2697
Y+C C G G+ C++ + +P
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNP 1415
Score = 73.2 bits (178), Expect = 4e-12
Identities = 91/368 (24%), Positives = 135/368 (36%), Gaps = 86/368 (23%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPS------------- 2149
CQ + C NG C + + + C CP ++G FCE + P
Sbjct: 1080 CQDNKCKNGAHC-----TDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGA 1134
Query: 2150 ------------------------------FNGNSYLELPFLKFVLEKEHNRTVTIYLTI 2179
N SYL++P K I L I
Sbjct: 1135 QCIVRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKV------RPQTNITLQI 1188
Query: 2180 KTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPI 2239
T+ +G +LY K + + L GR Y G+ SA YS+ T I
Sbjct: 1189 ATDEDSGILLYKG----DKDHIAVELYRGRVRASYDTGSH----PASAIYSVET-----I 1235
Query: 2240 TIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFES-MFLGHIP--ANVQIH 2296
V + + ++ DG P K T +S S F+S +++G +P +NV
Sbjct: 1236 NDGNFHIVELLALDQSLSLSVDGGNP--KIITNLSKQSTLNFDSPLYVGGMPGKSNVASL 1293
Query: 2297 KKAGPVYG--FRGCILDLQVNNK-EFFIIDEARHG--KNIENCHVPWCAHHLCRNNGTCI 2351
++A G F GCI +L +N++ + F + G E CH CAH C+
Sbjct: 1294 RQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGTCQP----- 1348
Query: 2352 SDNENLFCECPRLYSGKLCQFAS---CENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCT 2408
S CEC + G LC + C N C +G TC+P + C C G G LC
Sbjct: 1349 SSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHG-TCLPINAFSYSCKCLEGHGGVLCD 1407
Query: 2409 DAINITQP 2416
+ ++ P
Sbjct: 1408 EEEDLFNP 1415
Score = 70.9 bits (172), Expect = 2e-11
Identities = 77/317 (24%), Positives = 112/317 (35%), Gaps = 79/317 (24%)
Query: 297 PCVSLLFWKRGICPNSS-SAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDC-IKISND- 353
PC+S G C + Y CP G Q+ + + PC++G C +K +
Sbjct: 921 PCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEED 980
Query: 354 -VMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHC 412
CIC+ F C+ CE NN+TC +Y C C +T + CE+ +D C
Sbjct: 981 GFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFC 1040
Query: 413 KLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDK 472
C ++ C FK C PG + +H C + F CQD
Sbjct: 1041 AQDLNPCQHDSKCILTPKGFKCDCTPG-------------YVGEH---CDIDFDD-CQD- 1082
Query: 473 GPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTK 532
KC+ A+CT+ N +C
Sbjct: 1083 ------------------NKCKN--------GAHCTDAV--------NGYTC-------- 1100
Query: 533 EICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSC 592
IC G S L F ++ M L T+ +CQ+ A C IN P C C
Sbjct: 1101 -ICPEGYSGL------------FCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQC 1147
Query: 593 SLSYIGRLC--VVNVDY 607
Y G C +V+V++
Sbjct: 1148 LPGYQGEKCEKLVSVNF 1164
Score = 70.1 bits (170), Expect = 3e-11
Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Query: 716 GFSCLCNPGYVGIRCEQDIDD-CILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQES-- 772
GF+C C G++G C+Q +D C+ N C H + SY C CL G C++E
Sbjct: 1353 GFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEEDL 1412
Query: 773 -NECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEIN 811
N C+ CK+ CEC+SG+TG +C EI+
Sbjct: 1413 FNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREIS 1452
Score = 67.0 bits (162), Expect = 3e-10
Identities = 42/120 (35%), Positives = 54/120 (45%), Gaps = 14/120 (11%)
Query: 1011 EPCLHDGVCIDGINH------YTCDCKSGFFGTHCETNAND-CLSNPCLHGRCTEL-INE 1062
EPC H VC G +TC+C+ G+ G C+ ND CL N C+HG C +
Sbjct: 1334 EPC-HKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS 1392
Query: 1063 YPCSCDADGTSTQCKIK---INDCTSIPCMNEGFCQKSAHGFT-CICPRGYTGAYCEKSI 1118
Y C C C + N C +I C G C+ S G C C GYTG C++ I
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKC-KHGKCRLSGLGQPYCECSSGYTGDSCDREI 1451
Score = 64.7 bits (156), Expect = 1e-09
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 9/115 (7%)
Query: 1092 GFCQKSAH-GFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCL 1150
G CQ S+ GFTC C G+ G C++ + +P L + C++G C+ ++ C+CL
Sbjct: 1344 GTCQPSSQAGFTCECQEGWMGPLCDQRTN---DPCLGNK-CVHG-TCLPINAFSYSCKCL 1398
Query: 1151 PGFSGQFCEIN---INECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELEC 1202
G G C+ N C + C HG + C+C G++G C+ E+ C
Sbjct: 1399 EGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISC 1453
Score = 60.5 bits (145), Expect = 3e-08
Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Query: 735 DDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNE-CKMNPCKNNSTCTDLYKSY 793
+ C C H + + C C W G C+Q +N+ C N C + + SY
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSY 1393
Query: 794 RCECTSGWTGQNCSEE---INECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFC 846
C+C G G C EE N C + C + G C S + GQ C C YTG C
Sbjct: 1394 SCKCLEGHGGVLCDEEEDLFNPCQAIKCKH-GKCRLSGL-GQPYCECSSGYTGDSC 1447
Score = 58.5 bits (140), Expect = 1e-07
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 19/120 (15%)
Query: 935 EPCKN----NGTCVDLTNR-FFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD--- 986
EPC +GTC + F C C+ + GP C+ N PCL + CV+ T
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTN----DPCLGNK-CVHGTCLPI 1388
Query: 987 ---GYNCLCAPGYTGINCEINLD---ECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
Y+C C G+ G+ C+ D C + C H + G+ C+C SG+ G C+
Sbjct: 1389 NAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCD 1448
Score = 57.4 bits (137), Expect = 2e-07
Identities = 55/222 (24%), Positives = 86/222 (38%), Gaps = 29/222 (13%)
Query: 598 GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEID-TEDCKSASCKNGT 656
G+ V ++ G + S HG L N Q+ + E C C +GT
Sbjct: 1286 GKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGT 1345
Query: 657 TSTHLRGYFFRKCVPGFKGTQCEIDI-DECASHPCKNGATCIDQPGNYFCQCVPPFKVVD 715
+ F +C G+ G C+ D C + C +G TC+ P N F
Sbjct: 1346 CQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHG-TCL--PINAF----------- 1391
Query: 716 GFSCLCNPGYVGIRCEQDID---DCILNACEHNSTCKDLHLSY-QCVCLSDWEGNFCEQE 771
+SC C G+ G+ C+++ D C C+H C+ L C C S + G+ C++E
Sbjct: 1392 SYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGK-CRLSGLGQPYCECSSGYTGDSCDRE 1450
Query: 772 SNECKMNPCKN-------NSTCTDLYKSYRCECTSGWTGQNC 806
+ C+ ++ + C K R EC G G C
Sbjct: 1451 IS-CRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1491
Score = 56.2 bits (134), Expect = 5e-07
Identities = 38/165 (23%), Positives = 60/165 (36%), Gaps = 23/165 (13%)
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIP---G 831
C C + + + CEC GW G C + N DPC+ H + +P
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTN----DPCLGNKCVHGTCLPINAF 1391
Query: 832 QFVCLCPPLYTGQFCHQRYNLCDLLHNPCR----NNSTCLALVDANQHCICREEFEGKNC 887
+ C C + G C + +L NPC+ + C +C C + G +C
Sbjct: 1392 SYSCKCLEGHGGVLCDEEEDL----FNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSC 1447
Query: 888 EIDVKDC-------LFLSCQDYGDCEDMVNNFRCICRPGFSGSLC 925
+ ++ C + Q Y C+ R CR G +G C
Sbjct: 1448 DREIS-CRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1491
Score = 53.1 bits (126), Expect = 4e-06
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 9/83 (10%)
Query: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNL--CLHQSL 2926
NV DC+ N C N C ++C C P++ G C + + C +L C H S
Sbjct: 998 NVDDCED-----NDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSK 1052
Query: 2927 CIPDQSFSYSCLCTLGWVGRYCE 2949
CI + C CT G+VG +C+
Sbjct: 1053 CILTPK-GFKCDCTPGYVGEHCD 1074
Score = 52.8 bits (125), Expect = 5e-06
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLF-CECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTD-- 2393
C + C+N+GTC SD + + C CP + G+ C +C +NPC +G TC K G +
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDG 981
Query: 2394 IVCLCPYGRSGPLC 2407
C+C G G C
Sbjct: 982 FWCICADGFEGENC 995
Score = 52.8 bits (125), Expect = 5e-06
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 2614 CSLMKCGNGGTC-IESGTS--VYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
C C +GGTC ++ G +C C G++G C V C+ + C +TC+
Sbjct: 961 CISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCED-----NDCENNSTCVD 1015
Query: 2671 LPHGYTCFCPLGTTGIYCEQAL 2692
+ YTC CP TG CE+ L
Sbjct: 1016 GINNYTCLCPPEYTGELCEEKL 1037
Score = 52.4 bits (124), Expect = 7e-06
Identities = 34/98 (34%), Positives = 46/98 (46%), Gaps = 11/98 (11%)
Query: 2863 FGAKGGSNVGDCDGT--ACGYNTCRNGGECTVNGTT---FSCRCLPDWAGNTCNQSVS-C 2916
+G KG DCD AC N C++GG C + F C C + G C +V C
Sbjct: 947 YGFKGQ----DCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDC 1002
Query: 2917 LNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSF 2954
+N C + S C+ D +Y+CLC + G CE K F
Sbjct: 1003 EDNDCENNSTCV-DGINNYTCLCPPEYTGELCEEKLDF 1039
Score = 52.4 bits (124), Expect = 7e-06
Identities = 64/278 (23%), Positives = 116/278 (41%), Gaps = 45/278 (16%)
Query: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN--------QSVSCLNNLCLHQ 2924
D D C N C+NG CT ++C C ++G C ++ C N C +
Sbjct: 1074 DIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNG 1133
Query: 2925 SLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISL 2984
+ CI + C C G+ G CE S + SY++ P+ ++R T I+L
Sbjct: 1134 AQCIV-RINEPICQCLPGYQGEKCEKLVSVNFIN--KESYLQI--PSAKVR--PQTNITL 1186
Query: 2985 NFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGER----ISVPMSYNNGTFC 3040
+T + G++++ G + D +A+ L+ ++ + + G I + N+G F
Sbjct: 1187 QIATDEDSGILLYKG-----DKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNF- 1240
Query: 3041 CNKWHHVVVIQNQTLIKAYINNSLILSED------IDPHKNFVALNYDGICYLGGFEYGR 3094
H+V + ++ SL LS D I LN+D Y+GG
Sbjct: 1241 -----HIVEL-------LALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKS 1288
Query: 3095 KVNIVTQEIFK--TNFVGKIKDVVFFQEPKNIELIKLE 3130
V + Q + T+F G I+++ E ++ + + ++
Sbjct: 1289 NVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQ 1326
Score = 50.4 bits (119), Expect = 3e-05
Identities = 37/157 (23%), Positives = 60/157 (38%), Gaps = 12/157 (7%)
Query: 260 CQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAK-PCVSLLFWKRGICPNSSSAYTY 318
C VC HG C + F CEC E + GP C+ PC+ P ++ +Y+
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSC 1395
Query: 319 ECPKGSSSQNGETDVSEFS---LVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCE 375
+C +G + + F+ + C++G + C CS +T C + SC
Sbjct: 1396 KCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDR-EISCR 1454
Query: 376 SFPLRN-------NATCKKCEKDYPCSCISGFTEKNC 405
+R+ A C+ +K C G C
Sbjct: 1455 GERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1491
Score = 50.4 bits (119), Expect = 3e-05
Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE--CIPNSCVHELCME-NEPGSTC 1221
C C HG G+ C+CQ GW G C+ C+ N CVH C+ N +C
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSC 1395
Query: 1222 LCTPGFMTCSIGLLCGDE 1239
C G G+LC +E
Sbjct: 1396 KCLEGHG----GVLCDEE 1409
Score = 50.1 bits (118), Expect = 4e-05
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 17/119 (14%)
Query: 577 HEAVCKDEINRPR------CSCSLSYIGRLCVVNV-DYCLGNHSISVHGLCL---ALSHN 626
H+ VC +P C C ++G LC D CLGN VHG CL A S++
Sbjct: 1337 HKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC--VHGTCLPINAFSYS 1394
Query: 627 CNCSGLQRYERNICEIDTE---DCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDI 682
C C L+ + +C+ + + C++ CK+G G + +C G+ G C+ +I
Sbjct: 1395 CKC--LEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1451
Score = 49.3 bits (116), Expect = 6e-05
Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 6/121 (4%)
Query: 853 CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKD-CLFLSCQDYGDCEDM-VN 910
C+ H + TC A C C+E + G C+ D CL C +G C +
Sbjct: 1333 CEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCV-HGTCLPINAF 1391
Query: 911 NFRCICRPGFSGSLCEIE---INECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDV 967
++ C C G G LC+ E N C + CK+ + + +C C Y G C+ ++
Sbjct: 1392 SYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1451
Query: 968 N 968
+
Sbjct: 1452 S 1452
Score = 48.1 bits (113), Expect = 1e-04
Identities = 41/132 (31%), Positives = 55/132 (41%), Gaps = 20/132 (15%)
Query: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNN----STCLA 868
C C +G C S+ G F C C + G C QR N +PC N TCL
Sbjct: 1336 CHKKVCAHG-TCQPSSQAG-FTCECQEGWMGPLCDQRTN------DPCLGNKCVHGTCLP 1387
Query: 869 LVDANQHCICREEFEGKNCEIDVKDCLFLSCQ----DYGDCE-DMVNNFRCICRPGFSGS 923
+ + C C E G C D ++ LF CQ +G C + C C G++G
Sbjct: 1388 INAFSYSCKCLEGHGGVLC--DEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGD 1445
Query: 924 LCEIEINECSSE 935
C+ EI+ C E
Sbjct: 1446 SCDREIS-CRGE 1456
Score = 48.1 bits (113), Expect = 1e-04
Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 1046 CLSNPCLHGRCTELINE-YPCSCDADGTSTQCKIKIND-CTSIPCMNEGFCQKSAHGFTC 1103
C C HG C + C C C + ND C C++ +A ++C
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSC 1395
Query: 1104 ICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININ 1163
C G+ G C++ D ++ C +G + G G + C C G++G C+ I+
Sbjct: 1396 KCLEGHGGVLCDEEED--LFNPCQAIKCKHGKCRLSGLGQPY-CECSSGYTGDSCDREIS 1452
Score = 45.4 bits (106), Expect = 9e-04
Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 11/112 (9%)
Query: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQEL--DACSFKPCKNNGSCINKRENWDEQAYECV 243
HG C + + ++C CQ + G C + D C C + G+C+ + +Y C
Sbjct: 1343 HGTCQPSSQAG-FTCECQEGWMGPLCDQRTNDPCLGNKCVH-GTCLPI----NAFSYSCK 1396
Query: 244 CHPPFTGKNCSE---IIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
C G C E + CQ C HG C CEC ++G C+
Sbjct: 1397 CLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCD 1448
Score = 37.4 bits (85), Expect = 0.24
Identities = 59/255 (23%), Positives = 101/255 (39%), Gaps = 57/255 (22%)
Query: 1891 DSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYC 1950
+SYL+ + + PQ NI+L+ T G+LLY K D D ++L+ G ++ Y
Sbjct: 1168 ESYLQIPSAKVRPQTNITLQIATDEDSGILLY-KGDK---DHIAVELY--RGRVRAS-YD 1220
Query: 1951 PGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKS 2010
G +I + +++G + ++ LD + L++ G N +I +++ L
Sbjct: 1221 TGSHPASAIYSVETINDGN-FHIVELLALDQ-SLSLSVDGGNPKIITNLSKQ--STLNFD 1276
Query: 2011 GSVFIGGFPDLHGKIQM-PVPVKN---FTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQ 2066
+++GG P + P +N F GCI +N +IN+ Q
Sbjct: 1277 SPLYVGGMPGKSNVASLRQAPGQNGTSFHGCI-----------------RNLYINS-ELQ 1318
Query: 2067 GFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSF 2126
F P M T + P C + VC +G TC S F
Sbjct: 1319 DFQKVP----------------MQTGILPGCEP---CHKKVCAHG-TCQP----SSQAGF 1354
Query: 2127 QCDCPLHFTGRFCEK 2141
C+C + G C++
Sbjct: 1355 TCECQEGWMGPLCDQ 1369
Score = 34.3 bits (77), Expect = 2.0
Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 5/39 (12%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK 2141
C+ + C N TC GI ++ C CP +TG CE+
Sbjct: 1002 CEDNDCENNSTC-----VDGINNYTCLCPPEYTGELCEE 1035
Score = 33.9 bits (76), Expect = 2.6
Identities = 12/39 (30%), Positives = 20/39 (51%)
Query: 2612 SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS 2650
+PC +KC +G + YC C++G+ G C +S
Sbjct: 1414 NPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREIS 1452
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 175 bits (443), Expect = 7e-43
Identities = 110/351 (31%), Positives = 153/351 (43%), Gaps = 43/351 (12%)
Query: 910 NNFRCICRPGFSG----SLCEIEINECSSEPCKNNGTCVDLT---------NRFFCNCEP 956
N RCI F+G + + N+ SS P G+ DLT N C+C
Sbjct: 809 NRLRCIPVHAFNGLRSLRVLTLHGNDISSVP---EGSFNDLTSLSHLALGTNPLHCDCSL 865
Query: 957 EYHGPFCELDVNKCKISPCLDEENCVYR------TDGYNCLCAPGYTGINCEINLDECLS 1010
+ + + + I+ C E R T + C G IN + CLS
Sbjct: 866 RWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQC---KGPVDINIVAKCNACLS 922
Query: 1011 EPCLHDGVCI-DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINE----YPC 1065
PC ++G C D + Y C C + G C N C+ NPC HG L + + C
Sbjct: 923 SPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSC 982
Query: 1066 SCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPE 1125
SC +C+I +DC C N C + + CICP YTG C++ ID+C PE
Sbjct: 983 SCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV-PE 1041
Query: 1126 LNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVC 1185
LN +C + C+ F C C+PG+SG+ CE + ++C + C HGA C D INGY C
Sbjct: 1042 LN--LCQHEAKCIP-LDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTC 1098
Query: 1186 KCQPGWSGHHCEN--------ELECIPNSCVH-ELCMENEPGSTCLCTPGF 1227
C G+SG CE+ C C + C+ + TC C PGF
Sbjct: 1099 TCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGF 1149
Score = 173 bits (438), Expect = 3e-42
Identities = 90/273 (32%), Positives = 121/273 (44%), Gaps = 37/273 (13%)
Query: 851 NLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDC---ED 907
N C L +PC+NN TC C C ++GK+C + + C+ CQ G C +
Sbjct: 918 NAC--LSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDS 975
Query: 908 MVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDV 967
+ F C C GF G CEI ++C C+NN TCVD N + C C P Y G C+ +
Sbjct: 976 HKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVI 1035
Query: 968 NKC--KISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH 1025
+ C +++ C E C+ G++C C PGY+G CE + D+C++ C H C+D IN
Sbjct: 1036 DHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095
Query: 1026 YTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTS 1085
YTC C GF G CE H L+ PC
Sbjct: 1096 YTCTCPQGFSGPFCE------------HPPPMVLLQTSPCD------------------Q 1125
Query: 1086 IPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
C N C TC CP G+ G CEK I
Sbjct: 1126 YECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
Score = 157 bits (396), Expect = 2e-37
Identities = 82/244 (33%), Positives = 115/244 (47%), Gaps = 20/244 (8%)
Query: 930 NECSSEPCKNNGTCV-DLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVY---RT 985
N C S PCKNNGTC D + C C Y G C + +N C +PC C
Sbjct: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
Query: 986 DGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNAND 1045
DG++C C G+ G CEIN D+C C ++ C+DGIN+Y C C + G C+ +
Sbjct: 978 DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1037
Query: 1046 CLS--NPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFT 1102
C+ N C H +C L + C C + C+ +DC + C + C + +G+T
Sbjct: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
Query: 1103 CICPRGYTGAYCEK-------SIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSG 1155
C CP+G++G +CE C + E C NG C+ CRC PGF+G
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYE-----CQNGAQCIVVQQEP-TCRCPPGFAG 1151
Query: 1156 QFCE 1159
CE
Sbjct: 1152 PRCE 1155
Score = 152 bits (384), Expect = 5e-36
Identities = 94/316 (29%), Positives = 145/316 (45%), Gaps = 30/316 (9%)
Query: 586 NRPRCSCSLSYIGRLCVVN-----VDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNIC 640
N C CSL ++ + C ++ L +H C G + NI
Sbjct: 857 NPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKG--PVDINIV 914
Query: 641 EIDTEDCKSASCKNGTTSTHLRGYFFRKCVP-GFKGTQCEIDIDECASHPCKNGATCIDQ 699
C S+ CKN T T +R P +KG C + I+ C +PC++G TC
Sbjct: 915 A-KCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLS 973
Query: 700 PGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVC 759
+ DGFSC C G+ G RCE + DDC N CE+N+TC D +Y C+C
Sbjct: 974 DSHK-----------DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCIC 1022
Query: 760 LSDWEGNFCEQESNEC--KMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP 817
++ G C++ + C ++N C++ + C L K + CEC G++G+ C + ++C +
Sbjct: 1023 PPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHK 1082
Query: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNP-----CRNNSTCLALVDA 872
C +G C + TI G + C CP ++G FC + L +P C+N + C+ +V
Sbjct: 1083 CRHGAQCVD-TING-YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCI-VVQQ 1139
Query: 873 NQHCICREEFEGKNCE 888
C C F G CE
Sbjct: 1140 EPTCRCPPGFAGPRCE 1155
Score = 128 bits (321), Expect = 1e-28
Identities = 77/270 (28%), Positives = 112/270 (41%), Gaps = 70/270 (25%)
Query: 575 CQHEAVC-KDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQ 633
C++ C +D + RC+C SY G+ C V ++ C+
Sbjct: 925 CKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCI------------------------ 960
Query: 634 RYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNG 693
+N C+ S S K+G F C GF+G +CEI+ D+C + C+N
Sbjct: 961 ---QNPCQHGGTCHLSDSHKDG---------FSCSCPLGFEGQRCEINPDDCEDNDCENN 1008
Query: 694 ATCIDQPGNYFCQCVPPF------KVVD--------------------GFSCLCNPGYVG 727
ATC+D NY C C P + +V+D GFSC C PGY G
Sbjct: 1009 ATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSG 1068
Query: 728 IRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQ-------ESNECKMNPC 780
CE D DDC+ + C H + C D Y C C + G FCE +++ C C
Sbjct: 1069 KLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYEC 1128
Query: 781 KNNSTCTDLYKSYRCECTSGWTGQNCSEEI 810
+N + C + + C C G+ G C + I
Sbjct: 1129 QNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
Score = 124 bits (311), Expect = 1e-27
Identities = 103/365 (28%), Positives = 159/365 (43%), Gaps = 52/365 (14%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP-----------HHC 2662
C KC +G C+++ C C G+ G FC EH PP + C
Sbjct: 1078 CVAHKCRHGAQCVDTINGYTCTCPQGFSGPFC---------EHPPPMVLLQTSPCDQYEC 1128
Query: 2663 SRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQL 2722
GA CI + TC CP G G CE+ +++ +F + S++ AS VR + +I L
Sbjct: 1129 QNGAQCIVVQQEPTCRCPPGFAGPRCEKLITV---NFVGKD-SYVELASAKVRPQANISL 1184
Query: 2723 QFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRY-NLGDRTIILETLQKVTINGS 2781
Q +GIL Y + D L + L V+L Y +L + +++ T+N
Sbjct: 1185 QVATDKDNGILLYKGDN------DPLALELYQGHVRLVYDSLSSPPTTVYSVE--TVNDG 1236
Query: 2782 TWHIIKAGRVGAEGYLDLD-GINVTEKASTKMSSLDTNTDFYIGGV-SSLNLVNPMAIEN 2839
+H ++ + L +D G + K ++ N+ Y+GG+ +S L +
Sbjct: 1237 QFHSVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTD 1296
Query: 2840 EPV-GFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDG----TACGYNTCRNGGECTVNG 2894
P+ GF GCI +V INN +L +F A ++G G T C + CR +V
Sbjct: 1297 RPLGGFHGCIHEVRINN---ELQDFKALPPQSLGVSPGCKSCTVCKHGLCR-----SVEK 1348
Query: 2895 TTFSCRCLPDWAGNTCNQSV--SCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKT 2952
+ C C P W G C+Q CL + C H C+ + SY C C G+ G C+NK
Sbjct: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGT-SYMCKCAEGYGGDLCDNKN 1406
Query: 2953 SFSTA 2957
+ A
Sbjct: 1407 DSANA 1411
Score = 107 bits (266), Expect = 2e-22
Identities = 70/267 (26%), Positives = 110/267 (41%), Gaps = 40/267 (14%)
Query: 492 KCQGVIDAYFFLAAN------CTEDATYVNDP-EDNNSSCWFPHEGT----------KEI 534
+C+G +D N C + T DP E +C + ++G +
Sbjct: 904 QCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNP 963
Query: 535 CANGCSC-LSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCS 593
C +G +C LS+ + C L + G N D ++N+C++ A C D IN C C
Sbjct: 964 CQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICP 1023
Query: 594 LSYIGRLCVVNVDYCLGNHSISVH-GLCLALSHNCNCSGLQRYERNICEIDTEDCKSASC 652
+Y G LC +D+C+ ++ H C+ L +C + Y +CE D +DC + C
Sbjct: 1024 PNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKC 1083
Query: 653 KNGTTSTHLRGYFFRKCVPGFKGTQCE-------IDIDECASHPCKNGATCIDQPGNYFC 705
++G + C GF G CE + C + C+NGA CI
Sbjct: 1084 RHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCI-------- 1135
Query: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQ 732
V +C C PG+ G RCE+
Sbjct: 1136 ------VVQQEPTCRCPPGFAGPRCEK 1156
Score = 101 bits (252), Expect = 1e-20
Identities = 68/261 (26%), Positives = 108/261 (41%), Gaps = 17/261 (6%)
Query: 159 CPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDAC 217
C + +N+ K C LSS C +G C + + Y C C + GK C ++ C
Sbjct: 905 CKGPVDINIVAK---CNACLSSP-CKNNGTCTQDP-VELYRCACPYSYKGKDCTVPINTC 959
Query: 218 SFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNS 277
PC++ G+C + D + C C F G+ C C+ + C + N+
Sbjct: 960 IQNPCQHGGTCHLSDSHKD--GFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINN 1017
Query: 278 FICECDEQFSGPFCEVSAKPCVSLL--FWKRGICPNSSSAYTYECPKGSSSQNGETDVSE 335
++C C ++G C+ CV L C ++ EC G S + ETD +
Sbjct: 1018 YVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDD 1077
Query: 336 FSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKS------IQTS-CESFPLRNNATCKKC 388
C++G C+ N C C F+ C+ +QTS C+ + +N A C
Sbjct: 1078 CVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVV 1137
Query: 389 EKDYPCSCISGFTEKNCEKAI 409
+++ C C GF CEK I
Sbjct: 1138 QQEPTCRCPPGFAGPRCEKLI 1158
Score = 100 bits (248), Expect = 3e-20
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 9/215 (4%)
Query: 197 TYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
T+ C+ P + +AC PCKNNG+C + Y C C + GK+C+
Sbjct: 900 THRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQD----PVELYRCACPYSYKGKDCTVP 955
Query: 257 IGQCQPHVCFHGNCSNITSN---SFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSS 313
I C + C HG +++ + F C C F G CE++ C C +
Sbjct: 956 INTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGI 1015
Query: 314 SAYTYECPKGSSSQNGETDVSEF--SLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQ 371
+ Y CP + + + + L CQ+ CI + C C P ++ LC++
Sbjct: 1016 NNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDN 1075
Query: 372 TSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
C + R+ A C Y C+C GF+ CE
Sbjct: 1076 DDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
Score = 92.8 bits (229), Expect = 5e-18
Identities = 96/365 (26%), Positives = 141/365 (38%), Gaps = 53/365 (14%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC---------QFASCENNPCGNGATCVPK 2389
C H CR+ C+ C CP+ +SG C Q + C+ C NGA C+
Sbjct: 1078 CVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVV 1137
Query: 2390 SGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQ 2449
+ C CP G +GP C I + F G D +Y ++ + ++ Q
Sbjct: 1138 Q-QEPTCRCPPGFAGPRCEKLITV---NFVGKD--------SYVELASAKVRPQANISLQ 1185
Query: 2450 LANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSY-NLGSGIASIRSEPLNLS 2508
+A + N ++ + G +D LA+ L G V Y +L S ++ S
Sbjct: 1186 VATDK---DNGILLYKGD-------NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVND 1235
Query: 2509 LGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTP-DLLPNGA 2567
H+V L Q L VD KS+ + + + S Y+GG T L G
Sbjct: 1236 GQFHSVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGT 1295
Query: 2568 DFK-NGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCI 2626
D GF GCI +++ E F+ L P+ + G S G C++ C +G
Sbjct: 1296 DRPLGGFHGCIHEVRINNELQ-DFKAL-PPQ---SLGVSPG---CKSCTV--CKHGLCRS 1345
Query: 2627 ESGTSVYCNCTTGWKGSFCTETVSTCDPEHDP--PHHCSRGATCISLPHGYTCFCPLGTT 2684
SV C C GW G C + DP H C G C++ Y C C G
Sbjct: 1346 VEKDSVVCECRPGWTGPLCDQEA------RDPCLGHRCHHG-KCVATGTSYMCKCAEGYG 1398
Query: 2685 GIYCE 2689
G C+
Sbjct: 1399 GDLCD 1403
Score = 82.8 bits (203), Expect = 5e-15
Identities = 62/232 (26%), Positives = 82/232 (35%), Gaps = 78/232 (33%)
Query: 183 CSGHGKC-LSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAY 240
C G C LS++ +SC C F G+ C+ D C C+NN +C++ N Y
Sbjct: 964 CQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINN-----Y 1018
Query: 241 ECVCHPPFTGKNCSEIIGQCQP-------------------------------------- 262
C+C P +TG+ C E+I C P
Sbjct: 1019 VCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDC 1078
Query: 263 --HVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYEC 320
H C HG T N + C C + FSGPFCE P V L +S YE
Sbjct: 1079 VAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE-HPPPMVLL---------QTSPCDQYE- 1127
Query: 321 PKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQT 372
CQNG CI + + C C P F C+ + T
Sbjct: 1128 --------------------CQNGAQCIVVQQEPTCRCPPGFAGPRCEKLIT 1159
Score = 71.6 bits (174), Expect = 1e-11
Identities = 87/326 (26%), Positives = 135/326 (41%), Gaps = 63/326 (19%)
Query: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNG-NSYLELP 2159
S C Q C NG C + C CP F G CEK L +F G +SY+EL
Sbjct: 1121 SPCDQYECQNGAQCIVVQQEP-----TCRCPPGFAGPRCEK---LITVNFVGKDSYVELA 1172
Query: 2160 FLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNS 2219
K I L + T+ NG +LY N+ L L L +G + Y +S
Sbjct: 1173 SAKV------RPQANISLQVATDKDNGILLYKGDNDP----LALELYQGHVRLVYDSLSS 1222
Query: 2220 QNILTVSANYSINTNAFTPI-------TIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTE 2272
TV + ++N F + T+ G+P + ++ +P V
Sbjct: 1223 PPT-TVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPKSLGKLQK----QPAV------ 1271
Query: 2273 ISHASQAYFESMFLGHIPANVQIHK-KAG---PVYGFRGCILDLQVNN--KEFFIIDEAR 2326
++LG IP + + + G P+ GF GCI ++++NN ++F +
Sbjct: 1272 ------GINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQS 1325
Query: 2327 HG--KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS---CENNPCG 2381
G ++C V C H LCR+ + +++ CEC ++G LC + C + C
Sbjct: 1326 LGVSPGCKSCTV--CKHGLCRS-----VEKDSVVCECRPGWTGPLCDQEARDPCLGHRCH 1378
Query: 2382 NGATCVPKSGTDIVCLCPYGRSGPLC 2407
+G CV +GT +C C G G LC
Sbjct: 1379 HG-KCV-ATGTSYMCKCAEGYGGDLC 1402
Score = 64.7 bits (156), Expect = 1e-09
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 19/147 (12%)
Query: 1083 CTSIPCMNEGFCQK-SAHGFTCICPRGYTGAYCEKSI-DNCAEPELNSVICLNGGICVDG 1140
C S G C+ C C G+TG C++ D C + G CV
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH------GKCV-A 1384
Query: 1141 PGHTFDCRCLPGFSGQFCEI---NINECSSSPCLHGADCEDHINGY---VCKCQPGWSGH 1194
G ++ C+C G+ G C+ + N CS+ C HG + HI+ C CQPG+SG
Sbjct: 1385 TGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHG---QCHISDQGEPYCLCQPGFSGE 1441
Query: 1195 HCENELECIPNSCVHELCMENEPGSTC 1221
HC+ E C+ V E+ + ++C
Sbjct: 1442 HCQQENPCL-GQVVREVIRRQKGYASC 1467
Score = 62.4 bits (150), Expect = 7e-09
Identities = 53/193 (27%), Positives = 69/193 (35%), Gaps = 43/193 (22%)
Query: 919 GFSGSLCEIEINE------------------CSSEPCKNNGTCVDLT-NRFFCNCEPEYH 959
GF G + E+ IN C S +G C + + C C P +
Sbjct: 1301 GFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWT 1360
Query: 960 GPFCELDVNKCKISPCLDEE----NCVYRTDGYNCLCAPGYTGINCEINLDE---CLSEP 1012
GP C+ + PCL CV Y C CA GY G C+ D C +
Sbjct: 1361 GPLCDQEAR----DPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFK 1416
Query: 1013 CLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYP--CSCDAD 1070
C H I C C+ GF G HC+ NPCL E+I SC
Sbjct: 1417 CHHGQCHISDQGEPYCLCQPGFSGEHCQQ------ENPCLGQVVREVIRRQKGYASC--- 1467
Query: 1071 GTSTQCKIKINDC 1083
+T K+ I +C
Sbjct: 1468 --ATASKVPIMEC 1478
Score = 62.0 bits (149), Expect = 9e-09
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 6/176 (3%)
Query: 298 CVSLLFWKRGICPNSS-SAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCI---KISND 353
C+S G C Y CP ++ ++ PCQ+G C +
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
Query: 354 VMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCK 413
C C F C+ CE NNATC +Y C C +T + C++ IDHC
Sbjct: 980 FSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV 1039
Query: 414 LLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIH--QHLCYCGVTFHG 467
C +E C + F C+PG + C + + H +H C T +G
Sbjct: 1040 PELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095
Score = 60.1 bits (144), Expect = 3e-08
Identities = 33/95 (34%), Positives = 51/95 (53%), Gaps = 8/95 (8%)
Query: 2332 ENCHVP--WCAHHLCRNNGTC-ISDN--ENLFCECPRLYSGKLCQFA--SCENNPCGNGA 2384
++C VP C + C++ GTC +SD+ + C CP + G+ C+ CE+N C N A
Sbjct: 950 KDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNA 1009
Query: 2385 TCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFS 2419
TCV + VC+CP +G LC + I+ P +
Sbjct: 1010 TCVDGIN-NYVCICPPNYTGELCDEVIDHCVPELN 1043
Score = 59.3 bits (142), Expect = 6e-08
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Query: 1124 PELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININE-CSSSPCLHGADCEDHING 1182
P S G+C + C C PG++G C+ + C C HG C
Sbjct: 1330 PGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGK-CVATGTS 1388
Query: 1183 YVCKCQPGWSGHHCENELE----CIPNSCVHELCMENEPGST-CLCTPGF 1227
Y+CKC G+ G C+N+ + C C H C ++ G CLC PGF
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGF 1438
Score = 57.4 bits (137), Expect = 2e-07
Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 715 DGFSCLCNPGYVGIRCEQDI-DDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQE-- 771
D C C PG+ G C+Q+ D C+ + C H+ C SY C C + G+ C+ +
Sbjct: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYMCKCAEGYGGDLCDNKND 1407
Query: 772 -SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINEC 813
+N C C + C C G++G++C +E N C
Sbjct: 1408 SANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPC 1449
Score = 57.0 bits (136), Expect = 3e-07
Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 11/88 (12%)
Query: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
V +C+A C C N GTC + +Y C C +KG CT ++TC + C
Sbjct: 914 VAKCNA--CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTC-----IQNPCQH 966
Query: 2665 GATC-ISLPH--GYTCFCPLGTTGIYCE 2689
G TC +S H G++C CPLG G CE
Sbjct: 967 GGTCHLSDSHKDGFSCSCPLGFEGQRCE 994
Score = 56.2 bits (134), Expect = 5e-07
Identities = 31/74 (41%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLF-CECPRLYSGKLC--QFASCENNPCGNGATC-VPKSGTD- 2393
C C+NNGTC D L+ C CP Y GK C +C NPC +G TC + S D
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
Query: 2394 IVCLCPYGRSGPLC 2407
C CP G G C
Sbjct: 980 FSCSCPLGFEGQRC 993
Score = 55.1 bits (131), Expect = 1e-06
Identities = 54/197 (27%), Positives = 91/197 (46%), Gaps = 32/197 (16%)
Query: 2873 DCDGTACGYNTCRNGGEC--TVNGTTFSCRCLPDWAGNTCN--------QSVSCLNNLCL 2922
+ D C + CR+G +C T+NG ++C C ++G C Q+ C C
Sbjct: 1072 ETDNDDCVAHKCRHGAQCVDTING--YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQ 1129
Query: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMG-NSYIKYIDPNYRMRNLQFTT 2981
+ + CI Q +C C G+ G CE T F+G +SY++ R +
Sbjct: 1130 NGAQCIVVQQ-EPTCRCPPGFAGPRCE---KLITVNFVGKDSYVELASAKVRPQ----AN 1181
Query: 2982 ISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMS--YNNGTF 3039
ISL +T K G++++ G +ND LA+ L+ +++ + +S P + Y+ T
Sbjct: 1182 ISLQVATDKDNGILLYKG-----DNDPLALELYQGHVRLVY---DSLSSPPTTVYSVETV 1233
Query: 3040 CCNKWHHV-VVIQNQTL 3055
++H V +V NQTL
Sbjct: 1234 NDGQFHSVELVTLNQTL 1250
Score = 55.1 bits (131), Expect = 1e-06
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
Query: 264 VCFHGNCSNITSNSFICECDEQFSGPFCEVSAK-PCVSLLFWKRGICPNSSSAYTYECPK 322
VC HG C ++ +S +CEC ++GP C+ A+ PC+ G C + ++Y +C +
Sbjct: 1337 VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHR-CHHGKCVATGTSYMCKCAE 1395
Query: 323 GSSS---QNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCK 368
G N + S C +G I + C+C P F+ C+
Sbjct: 1396 GYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
Score = 53.1 bits (126), Expect = 4e-06
Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLN--NLCLHQSLCIP-DQSFS 2934
C N C N C + C C P++ G C++ + C+ NLC H++ CIP D+ F
Sbjct: 1000 CEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGF- 1058
Query: 2935 YSCLCTLGWVGRYCE 2949
SC C G+ G+ CE
Sbjct: 1059 -SCECVPGYSGKLCE 1072
Score = 53.1 bits (126), Expect = 4e-06
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 775 CKMNPCKNNSTCTDLYK-SYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPG-- 831
CK + C + K S CEC GWTG C +E DPC+ G CH
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----DPCL-GHRCHHGKCVATG 1386
Query: 832 -QFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE 888
++C C Y G C + + + ++ C +C+C+ F G++C+
Sbjct: 1387 TSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
Score = 50.8 bits (120), Expect = 2e-05
Identities = 64/268 (23%), Positives = 104/268 (38%), Gaps = 48/268 (17%)
Query: 1891 DSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYC 1950
DSY+E + + PQ NISL+ T G+LLY K D+ D ++L+ + L Y
Sbjct: 1166 DSYVELASAKVRPQANISLQVATDKDNGILLY-KGDN---DPLALELYQGHVRLVYDSLS 1221
Query: 1951 PGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKS 2010
S+ T V++GQ +++ EL L +++N V+ K PKS
Sbjct: 1222 SPPTTVYSVET---VNDGQFHSV-----------ELVTLN------QTLNLVVDKGTPKS 1261
Query: 2011 -------------GSVFIGGFPDLHGKIQM----PVPVKNFTGCIEVIEINNWRSFIPSK 2053
+++GG P G + P+ F GCI + INN +
Sbjct: 1262 LGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKAL 1321
Query: 2054 AVKNYHIN-NCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGG 2112
++ ++ C+S V+ V WT A C CH+G
Sbjct: 1322 PPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGK 1381
Query: 2113 TCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
+++G S+ C C + G C+
Sbjct: 1382 C-----VATG-TSYMCKCAEGYGGDLCD 1403
Score = 48.5 bits (114), Expect = 1e-04
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 13/108 (12%)
Query: 2878 ACGYNTCRNGGECTVNGTT-FSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFS- 2934
AC + C+N G CT + + C C + G C ++ C+ N C H C S
Sbjct: 919 ACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKD 978
Query: 2935 -YSCLCTLGWVGRYCE--------NKTSFSTAKFMG-NSYIKYIDPNY 2972
+SC C LG+ G+ CE N + G N+Y+ PNY
Sbjct: 979 GFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNY 1026
Score = 48.5 bits (114), Expect = 1e-04
Identities = 39/154 (25%), Positives = 58/154 (37%), Gaps = 20/154 (12%)
Query: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQE--LDACSFKPCKNNGSCINKRENWDEQAYECV 243
HG C S + C C+P ++G C + D C C ++G C+ + Y C
Sbjct: 1340 HGLCRSVE-KDSVVCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTS-----YMCK 1392
Query: 244 CHPPFTGKNC---SEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCV- 299
C + G C ++ C C HG C C C FSG C+ PC+
Sbjct: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ-QENPCLG 1451
Query: 300 ----SLLFWKRGI--CPNSSSAYTYECPKGSSSQ 327
++ ++G C +S EC G Q
Sbjct: 1452 QVVREVIRRQKGYASCATASKVPIMECRGGCGPQ 1485
Score = 46.2 bits (108), Expect = 5e-04
Identities = 39/129 (30%), Positives = 52/129 (40%), Gaps = 20/129 (15%)
Query: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCR----NNSTCLA 868
C S GLC S VC C P +TG C Q +PC ++ C+A
Sbjct: 1332 CKSCTVCKHGLCR-SVEKDSVVCECRPGWTGPLCDQE------ARDPCLGHRCHHGKCVA 1384
Query: 869 LVDANQHCICREEFEGKNCEI---DVKDCLFLSCQDYGDCE--DMVNNFRCICRPGFSGS 923
+ C C E + G C+ C C +G C D + C+C+PGFSG
Sbjct: 1385 -TGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCH-HGQCHISDQGEPY-CLCQPGFSGE 1441
Query: 924 LCEIEINEC 932
C+ E N C
Sbjct: 1442 HCQQE-NPC 1449
Score = 45.8 bits (107), Expect = 7e-04
Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 575 CQHEAVCKDEINRPRCSCSLSYIGRLCVVNV-DYCLGNHSISVHGLCLALSHNCNCSGLQ 633
C+H E + C C + G LC D CLG+ HG C+A + C +
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCH--HGKCVATGTSYMCKCAE 1395
Query: 634 RYERNICEIDTED---CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE 679
Y ++C+ + C + C +G +G + C PGF G C+
Sbjct: 1396 GYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
Score = 40.0 bits (92), Expect = 0.036
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
+ C Q+ C +GGTCH S F C CPL F G+ CE
Sbjct: 957 NTCIQNPCQHGGTCH--LSDSHKDGFSCSCPLGFEGQRCE 994
Score = 40.0 bits (92), Expect = 0.036
Identities = 30/128 (23%), Positives = 49/128 (38%), Gaps = 24/128 (18%)
Query: 613 SISVHGLCLALSHN---CNCSGLQRYERNICEIDTED-CKSASCKNGTTSTHLRGYFFRK 668
++ HGLC ++ + C C + +C+ + D C C +G Y K
Sbjct: 1336 TVCKHGLCRSVEKDSVVCECR--PGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMC-K 1392
Query: 669 CVPGFKGTQCEIDIDE---CASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGY 725
C G+ G C+ D C++ C +G I G +C C PG+
Sbjct: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCL--------------CQPGF 1438
Query: 726 VGIRCEQD 733
G C+Q+
Sbjct: 1439 SGEHCQQE 1446
Score = 35.8 bits (81), Expect = 0.69
Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 5/52 (9%)
Query: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFN 2151
P C+ + C N TC GI ++ C CP ++TG C++ P N
Sbjct: 997 PDDCEDNDCENNATC-----VDGINNYVCICPPNYTGELCDEVIDHCVPELN 1043
Score = 35.0 bits (79), Expect = 1.2
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 180 SEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDAC 217
S F HG+C + Y C CQP FSG++CQ+ + C
Sbjct: 1413 SAFKCHHGQCHISDQGEPY-CLCQPGFSGEHCQQENPC 1449
Score = 34.7 bits (78), Expect = 1.5
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 2374 SCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
+C ++PC N TC C CPY G CT IN
Sbjct: 919 ACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPIN 957
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 169 bits (429), Expect = 3e-41
Identities = 113/373 (30%), Positives = 161/373 (43%), Gaps = 44/373 (11%)
Query: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNP---CRNNSTCLAL 869
C S+PC NGG C + F C+CPP + G C N C++ C+N TC+
Sbjct: 136 CSSNPCQNGGTC--LNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNT 193
Query: 870 VDANQHCICREEFEGKNCEIDVKDCLFLSCQD--YGDCEDMVNN------FRCICRPGFS 921
+ + C C E G C DC S +G CED++ + C+C G+
Sbjct: 194 M-GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWM 252
Query: 922 GS----LCEIEINECSSEP--CKNNGTCVDLTNRFFCNCEP---EYHGPFCELDVNKCKI 972
S C ++ +ECS +P C C + F+C P + +G CE D+N+C+I
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICE-DINECEI 311
Query: 973 S----PCLDEENCVYRTDGYNC-LCAPGYTGINCEINLDECLSEP---CLHDGVCIDGIN 1024
+ CV +C C PGY G L + S C D C +
Sbjct: 312 NNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLG 371
Query: 1025 HYT-CDCKSGFFGTH-----CETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKI 1078
C C G+ G C +N CLS+PCL+G+C + ++ Y C CD+ T C
Sbjct: 372 SLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTE 431
Query: 1079 KINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICV 1138
IN+C S PC+N G C F+C C R +TGA C+ C E S+ +NG
Sbjct: 432 NINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGE----SLSGINGSFSY 487
Query: 1139 DGP--GHTFDCRC 1149
P G+ D C
Sbjct: 488 RSPDVGYVHDVNC 500
Score = 162 bits (410), Expect = 5e-39
Identities = 111/365 (30%), Positives = 157/365 (43%), Gaps = 57/365 (15%)
Query: 642 IDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASH-----PCKNGATC 696
+D + C S C+NG T +L FF C P +KG C D++EC + C+NG TC
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 697 IDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDC---ILNACEHNSTCKDL-- 751
++ G+Y SC C P G +C DDC + C H C+DL
Sbjct: 191 VNTMGSY--------------SCHCPPETYGPQCASKYDDCEGGSVARCVH-GICEDLMR 235
Query: 752 ----HLSYQCVCLSDW----EGNFCEQESNECKM--NPCKNNSTCTDLYKSYRC-ECTSG 800
Y CVC + W C + +EC PC C + S+ C C +G
Sbjct: 236 EQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTG 295
Query: 801 WTGQN-CSEEINECDSDPCMNGGLCHES------TIPGQFVC-LCPPLY--TGQFCHQRY 850
W G E+INEC+ +N G C + PG C CPP Y G+ C
Sbjct: 296 WQGNGYICEDINECE----INNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVC-TLT 350
Query: 851 NLCDLLHNPCRNNSTCLALVDANQHCICREEFEG-----KNCEIDVKDCLFLSCQDYGDC 905
++C + + C +++C + + + C C + G C CL C + G C
Sbjct: 351 DICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLN-GQC 409
Query: 906 EDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCEL 965
D V+ + C C G++G C INEC S PC N GTCVD + F C C + G C++
Sbjct: 410 IDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 469
Query: 966 DVNKC 970
C
Sbjct: 470 PQQVC 474
Score = 162 bits (410), Expect = 5e-39
Identities = 115/363 (31%), Positives = 161/363 (44%), Gaps = 49/363 (13%)
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECD---SDP--CMNGGLCHESTI 829
C NPC+N TC +L+ S+ C C W G CS ++NEC+ P C NGG C +
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM- 194
Query: 830 PGQFVCLCPPLYTGQFCHQRYNLCD------LLHNPCRNNSTCLALVDANQHCICREEF- 882
G + C CPP G C +Y+ C+ +H C + A + C+C +
Sbjct: 195 -GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQA-GEPKYSCVCDAGWM 252
Query: 883 ---EGKNCEIDVKDCLFL--SCQDYGDCEDMVNNFRC-ICRPGFSGS--LCEIEINECSS 934
C +D +C F C C + +F C C G+ G+ +CE +INEC
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICE-DINECEI 311
Query: 935 EPCKNNG--------TCVDLTNRFFCN-CEPEYHGP--FCEL-DVNKCKISPCLDEENCV 982
NNG CV+ C C P Y G C L D+ C + +C
Sbjct: 312 ----NNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCS 367
Query: 983 YRTDGYN-CLCAPGYTG-----INCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFG 1036
C C PGYTG C + CLS PCL +G CID ++ Y C C SG+ G
Sbjct: 368 STLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCL-NGQCIDTVSGYFCKCDSGWTG 426
Query: 1037 THCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDC-TSIPCMNEGFC 1094
+C N N+CLSNPCL+ G C + ++ + C C T C++ C S+ +N F
Sbjct: 427 VNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSFS 486
Query: 1095 QKS 1097
+S
Sbjct: 487 YRS 489
Score = 154 bits (389), Expect = 1e-36
Identities = 98/353 (27%), Positives = 157/353 (44%), Gaps = 33/353 (9%)
Query: 725 YVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMN-----P 779
+ G++ D C N C++ TC +LH S+ C+C W+G C + NEC++
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS 183
Query: 780 CKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP---CMNG---GLCHESTIPGQF 833
C+N TC + SY C C G C+ + ++C+ C++G L E ++
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKY 243
Query: 834 VCLCPPLY----TGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKN--C 887
C+C + C + C PC C + C ++G C
Sbjct: 244 SCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYIC 303
Query: 888 EIDVKDCLF----LSCQDYGDCEDMVNNFRC-ICRPGFSGS--LCEI-EINECSSEPCKN 939
E D+ +C S +C + + C C PG+ G +C + +I S+ C
Sbjct: 304 E-DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHP 362
Query: 940 NGTCVD-LTNRFFCNCEPEY----HGP-FCELDVNKCKISPCLDEENCVYRTDGYNCLCA 993
+ +C L + C C P Y +GP C N C PCL+ + C+ GY C C
Sbjct: 363 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCD 421
Query: 994 PGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDC 1046
G+TG+NC N++ECLS PCL+ G C+DG++ ++C+C + G C+ C
Sbjct: 422 SGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVC 474
Score = 150 bits (380), Expect = 1e-35
Identities = 110/353 (31%), Positives = 155/353 (43%), Gaps = 65/353 (18%)
Query: 920 FSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKI-----SP 974
F G ++ CSS PC+N GTC++L + FFC C P++ GP C DVN+C+I
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS 183
Query: 975 CLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLS---EPCLHDGVCID------GINH 1025
C + CV Y+C C P G C D+C C+H G+C D G
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH-GICEDLMREQAGEPK 242
Query: 1026 YTCDCKSGFF----GTHCETNANDCLSNPCLHGRCTELINEYPCS----CDADGTSTQ-- 1075
Y+C C +G+ C + ++C P G C+ L+ + C A T Q
Sbjct: 243 YSCVCDAGWMFSPNSPACTLDRDECSFQP---GPCSTLVQCFNTQGSFYCGACPTGWQGN 299
Query: 1076 ---------CKIKINDCTSIP---CMN---EGFCQKSAHGFTCICPRGY--TGAYCEKSI 1118
C+I C+ P C+N CQ CP GY G C +
Sbjct: 300 GYICEDINECEINNGGCSVAPPVECVNTPGSSHCQ--------ACPPGYQGDGRVCTLT- 350
Query: 1119 DNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSG-----QFCEININECSSSPCLHG 1173
D C+ +++ C C G C CLPG++G C N C S PCL+G
Sbjct: 351 DICS---VSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG 407
Query: 1174 ADCEDHINGYVCKCQPGWSGHHC-ENELECIPNSCVH-ELCMENEPGSTCLCT 1224
C D ++GY CKC GW+G +C EN EC+ N C++ C++ +C CT
Sbjct: 408 -QCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECT 459
Score = 132 bits (333), Expect = 4e-30
Identities = 102/362 (28%), Positives = 154/362 (42%), Gaps = 81/362 (22%)
Query: 881 EFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINEC---SSEP- 936
+F+G +D K C CQ+ G C ++ ++F CIC P + G LC ++NEC S P
Sbjct: 123 KFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPL 182
Query: 937 -CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK---ISPCLDE--ENCVYRTDG--- 987
C+N GTCV+ + C+C PE +GP C + C+ ++ C+ E+ + G
Sbjct: 183 SCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK 242
Query: 988 YNCLCAPGY----TGINCEINLDECLSEP--CLHDGVCIDGINHYTCD-CKSGFFGT--- 1037
Y+C+C G+ C ++ DEC +P C C + + C C +G+ G
Sbjct: 243 YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 302
Query: 1038 -----HCETNANDCLSNP---CLH-----------------GRCTEL-----INEYPCSC 1067
CE N C P C++ GR L ++ C
Sbjct: 303 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHP 362
Query: 1068 DADGTSTQCKIKI---------------------NDCTSIPCMNEGFCQKSAHGFTCICP 1106
DA +ST + + N C S PC+N G C + G+ C C
Sbjct: 363 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLN-GQCIDTVSGYFCKCD 421
Query: 1107 RGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECS 1166
G+TG C ++I+ C S CLNGG CVDG +F C C ++G C++ C
Sbjct: 422 SGWTGVNCTENINECL-----SNPCLNGGTCVDGVD-SFSCECTRLWTGALCQVPQQVCG 475
Query: 1167 SS 1168
S
Sbjct: 476 ES 477
Score = 122 bits (306), Expect = 6e-27
Identities = 98/364 (26%), Positives = 140/364 (38%), Gaps = 90/364 (24%)
Query: 564 LENTTDDQ---ENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYC------------ 608
L+ T D + N CQ+ C + + C C + G LC +V+ C
Sbjct: 127 LQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQN 186
Query: 609 -------LGNHSI-------------------------SVHGLCLAL--------SHNCN 628
+G++S VHG+C L ++C
Sbjct: 187 GGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 629 CSGLQRYERN--ICEIDTEDC--KSASCKNGTTSTHLRGYFF-RKCVPGFKG-------- 675
C + N C +D ++C + C + +G F+ C G++G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI 306
Query: 676 TQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDID 735
+CEI+ C+ P C++ PG+ CQ PP DG C DI
Sbjct: 307 NECEINNGGCSVAP---PVECVNTPGSSHCQACPPGYQGDGRVCTLT----------DIC 353
Query: 736 DCILNACEHNSTCKDLHLSYQ-CVCLSDWEG-----NFCEQESNECKMNPCKNNSTCTDL 789
C +++C S C CL + G N C Q SN C +PC N C D
Sbjct: 354 SVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDT 412
Query: 790 YKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQR 849
Y C+C SGWTG NC+E INEC S+PC+NGG C + F C C L+TG C
Sbjct: 413 VSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGV--DSFSCECTRLWTGALCQVP 470
Query: 850 YNLC 853
+C
Sbjct: 471 QQVC 474
Score = 117 bits (293), Expect = 2e-25
Identities = 95/355 (26%), Positives = 135/355 (38%), Gaps = 68/355 (19%)
Query: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQ-----ENECQHEAVCKDEINRPR 589
C NG +CL+ DS + +C +W G + + + + CQ+ C + +
Sbjct: 141 CQNGGTCLNLHDS--FFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYS 198
Query: 590 CSCSLSYIGRLCVVNVDYCLGNH-SISVHGLCLAL--------SHNCNCSGLQRYERN-- 638
C C G C D C G + VHG+C L ++C C + N
Sbjct: 199 CHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSP 258
Query: 639 ICEIDTEDC--KSASCKNGTTSTHLRGYFF-RKCVPGFKGT--------QCEIDIDECAS 687
C +D ++C + C + +G F+ C G++G +CEI+ C+
Sbjct: 259 ACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSV 318
Query: 688 HPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCL--------------------------- 720
P C++ PG+ CQ PP DG C
Sbjct: 319 AP---PVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPL 375
Query: 721 --CNPGYVGIR-----CEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESN 773
C PGY G C Q + C+ + C N C D Y C C S W G C + N
Sbjct: 376 CTCLPGYTGNGYGPNGCVQLSNICLSHPCL-NGQCIDTVSGYFCKCDSGWTGVNCTENIN 434
Query: 774 ECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINEC-DSDPCMNGGLCHES 827
EC NPC N TC D S+ CECT WTG C C +S +NG + S
Sbjct: 435 ECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSFSYRS 489
Score = 72.0 bits (175), Expect = 9e-12
Identities = 82/346 (23%), Positives = 116/346 (33%), Gaps = 88/346 (25%)
Query: 165 LNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ----ELDACSFK 220
L TV ++ C SS C G CL+ ++ C C P + G C E + S
Sbjct: 127 LQQTVDKKVC----SSNPCQNGGTCLN--LHDSFFCICPPQWKGPLCSADVNECEIYSGT 180
Query: 221 P--CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHV---CFHGNCSNITS 275
P C+N G+C+N + Y C C P G C+ C+ C HG C ++
Sbjct: 181 PLSCQNGGTCVNTMGS-----YSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMR 235
Query: 276 NS-----FICECDEQF----SGPFCEVSAK-------PCVSLL-------FWKRGICPNS 312
+ C CD + + P C + PC +L+ + G CP
Sbjct: 236 EQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTG 295
Query: 313 ---------------------------------SSAYTYECPKGSSSQNGE---TDVSEF 336
S++ CP G TD+
Sbjct: 296 WQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSV 355
Query: 337 SLVPCQNGTDCIKISNDV-MCICSPIFTDLL-----CKSIQTSCESFPLRNNATCKKCEK 390
S C C + +C C P +T C + C S P N C
Sbjct: 356 SNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVS 414
Query: 391 DYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVC 436
Y C C SG+T NC + I+ C LS CLN C + + F C
Sbjct: 415 GYFCKCDSGWTGVNCTENINEC--LSNPCLNGGTCVDGVDSFSCEC 458
Score = 72.0 bits (175), Expect = 9e-12
Identities = 87/385 (22%), Positives = 125/385 (32%), Gaps = 97/385 (25%)
Query: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQ-----PHVCFHGNCS 271
CS PC+N G+C+N + ++ C+C P + G CS + +C+ P C +G
Sbjct: 136 CSSNPCQNGGTCLNLHD-----SFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190
Query: 272 NITSNSFICECDEQFSGPFCEVSAKPCV--SLLFWKRGICPN------SSSAYTYECPKG 323
T S+ C C + GP C C S+ GIC + Y+ C G
Sbjct: 191 VNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAG 250
Query: 324 ------SSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI---FTDLLCKSIQTSC 374
S + + D F PC C C P +C+ I C
Sbjct: 251 WMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI-NEC 309
Query: 375 ESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA-------------IDHCKLLSINCLN 421
E NN C P C++ +C+ D C + + C
Sbjct: 310 EI----NNGGCSVAP---PVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHP 362
Query: 422 EEWCFNIIGRFKY-VCIPGCT-----KNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPA 475
+ C + +G C+PG T N C L N+ L H C G
Sbjct: 363 DASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICL--SHPCLNG------------- 407
Query: 476 QFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEIC 535
+C + YF C T VN E+ N P C
Sbjct: 408 ----------------QCIDTVSGYF---CKCDSGWTGVNCTENINECLSNP-------C 441
Query: 536 ANGCSCLSEEDSQEYRYLCFLRWAG 560
NG +C+ DS + C W G
Sbjct: 442 LNGGTCVDGVDS--FSCECTRLWTG 464
Score = 69.7 bits (169), Expect = 4e-11
Identities = 29/75 (38%), Positives = 37/75 (49%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
CS C NGGTC+ S +C C WKG C+ V+ C+ P C G TC++
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMG 195
Query: 2674 GYTCFCPLGTTGIYC 2688
Y+C CP T G C
Sbjct: 196 SYSCHCPPETYGPQC 210
Score = 63.9 bits (154), Expect = 2e-09
Identities = 95/405 (23%), Positives = 140/405 (34%), Gaps = 54/405 (13%)
Query: 276 NSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECP---KG--SSSQNGE 330
NS + + + +F G V K C S G C N ++ CP KG S+ E
Sbjct: 114 NSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNE 173
Query: 331 TDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRN--NATCKKC 388
++ + + CQNG C+ C C P C S CE + + C+
Sbjct: 174 CEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDL 233
Query: 389 ------EKDYPCSCISGF----TEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP 438
E Y C C +G+ C D C C CFN G F
Sbjct: 234 MREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFY----- 288
Query: 439 GCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVID 498
C P + N Y I + + C + +G C P + + GS CQ
Sbjct: 289 -CGACPTGWQGNGY-ICEDINECEIN-NGGCSVAPPVEC-----VNTPGS--SHCQACPP 338
Query: 499 AYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRW 558
Y CT C + G C SC S S C +
Sbjct: 339 GYQGDGRVCT-----------LTDICSVSNGG----CHPDASCSSTLGSLPL-CTCLPGY 382
Query: 559 AGNMYLENTTDDQENEC-QHEAV---CKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSI 614
GN Y N N C H + C D ++ C C + G C N++ CL N +
Sbjct: 383 TGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCL 442
Query: 615 SVHGLCLALSHNCNCSGLQRYERNICEIDTEDC-KSASCKNGTTS 658
+ G C+ + +C + + +C++ + C +S S NG+ S
Sbjct: 443 N-GGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSFS 486
Score = 60.5 bits (145), Expect = 3e-08
Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 13/128 (10%)
Query: 177 SLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKY-----CQEL-DACSFKPCKNNGSCIN 230
S+S+ C C S S C C P ++G C +L + C PC N G CI+
Sbjct: 354 SVSNGGCHPDASCSSTLGSLPL-CTCLPGYTGNGYGPNGCVQLSNICLSHPCLN-GQCID 411
Query: 231 KRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPF 290
Y C C +TG NC+E I +C + C +G +SF CEC ++G
Sbjct: 412 T-----VSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGAL 466
Query: 291 CEVSAKPC 298
C+V + C
Sbjct: 467 CQVPQQVC 474
Score = 53.5 bits (127), Expect = 3e-06
Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCE---NNP--CGNGATCVPKSG 2391
C+ + C+N GTC++ +++ FC CP + G LC CE P C NG TCV G
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMG 195
Query: 2392 TDIVCLCPYGRSGPLC 2407
+ C CP GP C
Sbjct: 196 S-YSCHCPPETYGPQC 210
Score = 52.4 bits (124), Expect = 7e-06
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
C + C NG +C + + C+C W G C ++++ CL+N CL+ C+ D S+SC
Sbjct: 399 CLSHPCLNG-QCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCV-DGVDSFSC 456
Query: 2938 LCTLGWVGRYCE 2949
CT W G C+
Sbjct: 457 ECTRLWTGALCQ 468
Score = 52.0 bits (123), Expect = 9e-06
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 11/96 (11%)
Query: 2594 GNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653
GN G + C + PC G CI++ + +C C +GW G CTE ++ C
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCL------NGQCIDTVSGYFCKCDSGWTGVNCTENINEC- 436
Query: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
+ C G TC+ ++C C TG C+
Sbjct: 437 ----LSNPCLNGGTCVDGVDSFSCECTRLWTGALCQ 468
Score = 51.2 bits (121), Expect = 2e-05
Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 26/185 (14%)
Query: 207 SGKYCQELDACSFKPCKNNGSCINKRE----NWDEQAYECVCHPPFTGKN--------CS 254
+G C++++ C NNG C N ++ C P + G CS
Sbjct: 299 NGYICEDINECEI----NNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICS 354
Query: 255 EIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPF-----CEVSAKPCVSLLFWKRGIC 309
G C P +CS+ + +C C ++G C + C+S G C
Sbjct: 355 VSNGGCHPDA----SCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLN-GQC 409
Query: 310 PNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKS 369
++ S Y +C G + N +++E PC NG C+ + C C+ ++T LC+
Sbjct: 410 IDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 469
Query: 370 IQTSC 374
Q C
Sbjct: 470 PQQVC 474
Score = 48.5 bits (114), Expect = 1e-04
Identities = 77/291 (26%), Positives = 100/291 (34%), Gaps = 73/291 (25%)
Query: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDAC---SFKPCKNNGSCIN-KRENWDE 237
C G C++ S YSCHC P G C + D C S C + G C + RE E
Sbjct: 184 CQNGGTCVNTMGS--YSCHCPPETYGPQCASKYDDCEGGSVARCVH-GICEDLMREQAGE 240
Query: 238 QAYECVCH---------PPFT--GKNCSEIIGQCQPHV-CFH-------GNC-SNITSNS 277
Y CVC P T CS G C V CF+ G C + N
Sbjct: 241 PKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNG 300
Query: 278 FICE----CDEQFSGPFCEVSAK-PCVS-------------------------LLFWKRG 307
+ICE C+ G C V+ CV+ + G
Sbjct: 301 YICEDINECEINNGG--CSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG 358
Query: 308 IC-PNSSSAYTY------ECPKGSSSQ----NGETDVSEFSLV-PCQNGTDCIKISNDVM 355
C P++S + T C G + NG +S L PC NG CI +
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYF 417
Query: 356 CICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
C C +T + C C S P N TC + C C +T C+
Sbjct: 418 CKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQ 468
Score = 47.8 bits (112), Expect = 2e-04
Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTD-IV 2395
C H C N G CI FC+C ++G C C +NPC NG TCV G D
Sbjct: 399 CLSHPCLN-GQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCV--DGVDSFS 455
Query: 2396 CLCPYGRSGPLCTDAINITQPRFSGTD-AFGYTS 2428
C C +G LC + SG + +F Y S
Sbjct: 456 CECTRLWTGALCQVPQQVCGESLSGINGSFSYRS 489
Score = 45.8 bits (107), Expect = 7e-04
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 7/83 (8%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV------SCLNNLCLHQSLCI 2928
D C N C+NGG C +F C C P W G C+ V S C + C+
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCV 191
Query: 2929 PDQSFSYSCLCTLGWVGRYCENK 2951
SYSC C G C +K
Sbjct: 192 NTMG-SYSCHCPPETYGPQCASK 213
Score = 42.0 bits (97), Expect = 0.010
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 23/107 (21%)
Query: 2283 SMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIEN-------CH 2335
S LG +P + G YG GC+ Q++N + +G+ I+ C
Sbjct: 367 SSTLGSLPLCTCLPGYTGNGYGPNGCV---QLSN--ICLSHPCLNGQCIDTVSGYFCKCD 421
Query: 2336 VPW-----------CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ 2371
W C + C N GTC+ ++ CEC RL++G LCQ
Sbjct: 422 SGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQ 468
Score = 42.0 bits (97), Expect = 0.010
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 5/52 (9%)
Query: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTC 2652
N ++ +C ++PC NGGTC++ S C CT W G+ C C
Sbjct: 428 NCTENINECLSNPCL-----NGGTCVDGVDSFSCECTRLWTGALCQVPQQVC 474
Score = 40.8 bits (94), Expect = 0.021
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 27/146 (18%)
Query: 2087 DTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC---EKDA 2143
D+ WT V+ + + C + C NGGTC G+ SF C+C +TG C ++
Sbjct: 421 DSGWTGVNCTENI-NECLSNPCLNGGTC-----VDGVDSFSCECTRLWTGALCQVPQQVC 474
Query: 2144 GLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTIL--------YSNGNN 2195
G NG+ P + +V V + IKT G +L + +N
Sbjct: 475 GESLSGINGSFSYRSPDVGYV------HDVNCFWVIKTEM--GKVLRITFTFFRLESMDN 526
Query: 2196 CGKQFLHLFLVEGRPSVKYG--CGNS 2219
C +FL ++ + + + G CG+S
Sbjct: 527 CPHEFLQVYDGDSSSAFQLGRFCGSS 552
Score = 40.0 bits (92), Expect = 0.036
Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 16/88 (18%)
Query: 2869 SNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS---------CLNN 2919
++V +C+ + +C+NGG C ++SC C P+ G C C++
Sbjct: 169 ADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHG 228
Query: 2920 LC---LHQSLCIPDQSFSYSCLCTLGWV 2944
+C + + P YSC+C GW+
Sbjct: 229 ICEDLMREQAGEP----KYSCVCDAGWM 252
Score = 39.7 bits (91), Expect = 0.048
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 2375 CENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGT 2421
C +NPC NG TC+ + C+CP GPLC+ +N + +SGT
Sbjct: 136 CSSNPCQNGGTCLNLHDS-FFCICPPQWKGPLCSADVNECE-IYSGT 180
Score = 37.7 bits (86), Expect = 0.18
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 10/68 (14%)
Query: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAG-------NTCNQSVSCLNNLCLHQSLCIPDQ 2931
C N C NGG C +FSC C W G C +S+S +N ++S PD
Sbjct: 436 CLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSFSYRS---PDV 492
Query: 2932 SFSYSCLC 2939
+ + C
Sbjct: 493 GYVHDVNC 500
Score = 36.6 bits (83), Expect = 0.40
Identities = 49/171 (28%), Positives = 62/171 (36%), Gaps = 47/171 (27%)
Query: 2809 STKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQG----C--IRQVIINNQELQLTE 2862
ST + +T FY G P G+QG C I + INN +
Sbjct: 275 STLVQCFNTQGSFYCGAC--------------PTGWQGNGYICEDINECEINNGGCSVAP 320
Query: 2863 ----FGAKGGSNVGDC------DGTACGYN---TCRNGG-----ECTVN-GTTFSCRCLP 2903
G S+ C DG C + NGG C+ G+ C CLP
Sbjct: 321 PVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP 380
Query: 2904 DWAG-----NTCNQ-SVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
+ G N C Q S CL++ CL+ CI D Y C C GW G C
Sbjct: 381 GYTGNGYGPNGCVQLSNICLSHPCLN-GQCI-DTVSGYFCKCDSGWTGVNC 429
Score = 36.2 bits (82), Expect = 0.53
Identities = 29/110 (26%), Positives = 43/110 (39%), Gaps = 14/110 (12%)
Query: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIES-GTSVYCNCTTGWKGSF-----CTETV 2649
P G+ GR S C +C + G+ C C G+ G+ C +
Sbjct: 337 PPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS 396
Query: 2650 STCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS--ISDP 2697
+ C H C G CI GY C C G TG+ C + ++ +S+P
Sbjct: 397 NIC-----LSHPCLNGQ-CIDTVSGYFCKCDSGWTGVNCTENINECLSNP 440
Score = 35.4 bits (80), Expect = 0.90
Identities = 15/54 (27%), Positives = 22/54 (40%)
Query: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD 2653
P V +C + + C NGGTC+ + S C+C G C C+
Sbjct: 165 PLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCE 218
Score = 33.1 bits (74), Expect = 4.4
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 5/41 (12%)
Query: 2102 VCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
VC + C NGGTC + SF C CP + G C D
Sbjct: 135 VCSSNPCQNGGTCLNLH-----DSFFCICPPQWKGPLCSAD 170
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 169 bits (428), Expect = 4e-41
Identities = 85/246 (34%), Positives = 120/246 (48%), Gaps = 15/246 (6%)
Query: 735 DDCILNACEHNSTCKDLHLS-YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKS- 792
D C+ + C++ TC + L Y+C C S ++G CE + C PC+N TC
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 793 --YRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRY 850
+ C C +G+ G C ++C C NGG+C + G + C CP Y G+ C Q
Sbjct: 987 APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGV--GNYTCQCPLQYEGKACEQLV 1044
Query: 851 NLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVN 910
+LC NPC++ + C+ D + C C + G NC + DC CQ+ C D VN
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPR-CECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVN 1103
Query: 911 NFRCICRPGFSGSLCEIEIN------ECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE 964
++ C+C G+SG LCEI + C C+N CVD NR C C P + GP CE
Sbjct: 1104 SYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Query: 965 --LDVN 968
L VN
Sbjct: 1164 KLLSVN 1169
Score = 155 bits (391), Expect = 8e-37
Identities = 92/291 (31%), Positives = 122/291 (41%), Gaps = 25/291 (8%)
Query: 795 CEC----TSGWTGQNCSEE-INECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQR 849
C+C S W E I C M G L +T +F C PP Q
Sbjct: 870 CDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLL-TTPAKKFECQGPPTLAVQA---- 924
Query: 850 YNLCDL-LHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDM 908
CDL L +PC+N TC C C ++G++CE+ + C C++ G C
Sbjct: 925 --KCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 909 VNN---FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCEL 965
F C C GF G C + ++C C N G CVD + C C +Y G CE
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQ 1042
Query: 966 DVNKCK--ISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGI 1023
V+ C ++PC E CV DG C C PGY G NC N D+C C + C+D +
Sbjct: 1043 LVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEV 1102
Query: 1024 NHYTCDCKSGFFGTHCE------TNANDCLSNPCLHG-RCTELINEYPCSC 1067
N Y+C C G+ G CE + C C +G C + N C C
Sbjct: 1103 NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQC 1153
Score = 154 bits (388), Expect = 2e-36
Identities = 82/244 (33%), Positives = 118/244 (48%), Gaps = 19/244 (7%)
Query: 970 CKISPCLDEENCVYRT-DGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH--- 1025
C SPC ++ C + Y C C GY G +CE++LD C S PC + G C
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988
Query: 1026 YTCDCKSGFFGTHCETNANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCT 1084
+TC C +GF G C N +DC+ + C +G C + + Y C C C+ ++ C+
Sbjct: 989 FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1048
Query: 1085 SI--PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPG 1142
PC +E C + G C C GY G C ++ D+C + C NG C+D
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHR-----CQNGAQCMDEV- 1102
Query: 1143 HTFDCRCLPGFSGQFCEININ------ECSSSPCLHGADCEDHINGYVCKCQPGWSGHHC 1196
+++ C C G+SGQ CEI + C + C +GA+C D N VC+C PG+ G C
Sbjct: 1103 NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPEC 1162
Query: 1197 ENEL 1200
E L
Sbjct: 1163 EKLL 1166
Score = 152 bits (383), Expect = 7e-36
Identities = 92/299 (30%), Positives = 129/299 (43%), Gaps = 26/299 (8%)
Query: 948 NRFFCNCEPEYHGPFCELDVNKCKISPCL---DEENCVYRTDGYNCLCAPGYTGINCEIN 1004
N +C+C + + + + I+ C D E + T G + +
Sbjct: 866 NPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLAVQAK 925
Query: 1005 LDECLSEPCLHDGVCI-DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINE 1062
D CLS PC + G C D + Y C C SG+ G CE + + C S PC +G C E
Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGE 985
Query: 1063 ---YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSID 1119
+ CSC C + +DC C N G C +TC CP Y G CE+ +D
Sbjct: 986 DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVD 1045
Query: 1120 NCAEPELNSVICLNGGICV---DGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADC 1176
C+ P+LN C + CV DGP C C+PG++G C N ++C C +GA C
Sbjct: 1046 LCS-PDLNP--CQHEAQCVGTPDGPR----CECMPGYAGDNCSENQDDCRDHRCQNGAQC 1098
Query: 1177 EDHINGYVCKCQPGWSGHHCE-------NELECIPNSCVHEL-CMENEPGSTCLCTPGF 1227
D +N Y C C G+SG CE + C C + C++ C C PGF
Sbjct: 1099 MDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGF 1157
Score = 137 bits (345), Expect = 2e-31
Identities = 80/267 (29%), Positives = 116/267 (43%), Gaps = 42/267 (15%)
Query: 608 CLGNHSISVHGLC-LALSHNCN--------------CSGLQRYERNICEIDTEDCKSASC 652
C G +++V C L LS C C+ Y+ CE+ + C S C
Sbjct: 914 CQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPC 973
Query: 653 KNGTTSTHLRGY---FFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVP 709
+NG T G F C GF+G C ++ D+C H C NG C+D GNY CQC
Sbjct: 974 ENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQC-- 1031
Query: 710 PFKVVDGFSCLCNPGYVGIRCEQDIDDCI--LNACEHNSTCKDLHLSYQCVCLSDWEGNF 767
P + Y G CEQ +D C LN C+H + C +C C+ + G+
Sbjct: 1032 PLQ------------YEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDN 1079
Query: 768 CEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCS------EEINECDSDPCMNG 821
C + ++C+ + C+N + C D SY C C G++GQ C + C+ C NG
Sbjct: 1080 CSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNG 1139
Query: 822 GLCHESTIPGQFVCLCPPLYTGQFCHQ 848
C + + VC C P + G C +
Sbjct: 1140 ANCVDQ--GNRPVCQCLPGFGGPECEK 1164
Score = 117 bits (294), Expect = 1e-25
Identities = 79/270 (29%), Positives = 107/270 (39%), Gaps = 37/270 (13%)
Query: 1022 GINHYTCDCKSGFFGTHCETNAND-----CLSNPCLHGRCTELINEYPCSCDADGTSTQC 1076
G N CDC + + +T + C + G+ C T
Sbjct: 864 GANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLA-V 922
Query: 1077 KIKINDCTSIPCMNEGFCQKSA-HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGG 1135
+ K + C S PC N+G C + C CP GY G CE S+D+C+ S C NGG
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCS-----SGPCENGG 977
Query: 1136 IC--VDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSG 1193
C +G F C C GF G C +N ++C C +G C D + Y C+C + G
Sbjct: 978 TCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG 1037
Query: 1194 HHCENELE-CIP--NSCVHEL-CMENEPGSTCLCTPGFM--------------TCSIGLL 1235
CE ++ C P N C HE C+ G C C PG+ C G
Sbjct: 1038 KACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQ 1097
Query: 1236 CGDEIRRITCLTPIFQRTDPISTQTYTIPP 1265
C DE+ +CL + S Q IPP
Sbjct: 1098 CMDEVNSYSCLC-----AEGYSGQLCEIPP 1122
Score = 109 bits (272), Expect = 5e-23
Identities = 136/612 (22%), Positives = 212/612 (34%), Gaps = 144/612 (23%)
Query: 575 CQHEAVC-KDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHN---CNCS 630
CQ++ C D + RC+C Y GR C V++D C + G C A CS
Sbjct: 934 CQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSC-SSGPCENGGTCHAQEGEDAPFTCS 992
Query: 631 GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECAS--H 688
+E C ++T+DC +C NG G + +C ++G CE +D C+ +
Sbjct: 993 CPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 689 PCKNGATCIDQPGNYFCQCVPPFK------------------------VVDGFSCLCNPG 724
PC++ A C+ P C+C+P + V+ +SCLC G
Sbjct: 1053 PCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEG 1112
Query: 725 YVGIRCE------QDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMN 778
Y G CE C C++ + C D C CL + G EC+
Sbjct: 1113 YSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGP-------ECE-K 1164
Query: 779 PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCM--NGGLCH----------- 825
N D Y + W N + +++ + + + NG H
Sbjct: 1165 LLSVNFVDRDTYLQFTD--LQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVR 1222
Query: 826 ----ESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREE 881
+ P + + GQF D + N + + + + + +H E
Sbjct: 1223 VSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSE 1282
Query: 882 ---FEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCK 938
+ G +DV F Q ++N GF G + + IN + K
Sbjct: 1283 APLYVG-GMPVDVNSAAFRLWQ-------ILNG------TGFHGCIRNLYINNELQDFTK 1328
Query: 939 NNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTG 998
+ CEP C+ CL T G C C G+ G
Sbjct: 1329 TQ-----MKPGVVPGCEP-------------CRKLYCLHGICQPNATPGPMCHCEAGWVG 1370
Query: 999 INCEINLD-ECLSEPCLHDGVCI--DGINHYTCDCKSGFFGTHCE---TNANDCLSNPCL 1052
++C+ D C C+H G C+ D ++ Y+C C+ G+ G C A C CL
Sbjct: 1371 LHCDQPADGPCHGHKCVH-GQCVPLDALS-YSCQCQDGYSGALCNQAGALAEPCRGLQCL 1428
Query: 1053 HGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGA 1112
HG C A GT K AH C+C G++G
Sbjct: 1429 HGH-----------CQASGT-----------------------KGAH---CVCDPGFSGE 1451
Query: 1113 YCEKSIDNCAEP 1124
CE+ + +P
Sbjct: 1452 LCEQESECRGDP 1463
Score = 108 bits (270), Expect = 8e-23
Identities = 101/376 (26%), Positives = 149/376 (39%), Gaps = 58/376 (15%)
Query: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--------ASCENNPCGNGATCVPKS 2390
C H C+N C+ + + C C YSG+LC+ + CE C NGA CV +
Sbjct: 1087 CRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQ- 1145
Query: 2391 GTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQL 2450
G VC C G GP C +++ F D Y + +D+ ++ Q+
Sbjct: 1146 GNRPVCQCLPGFGGPECEKLLSV---NFVDRD--------TYLQFTDLQNWPRANITLQV 1194
Query: 2451 ANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLNLSLG 2510
+ +A N ++ + G H +AV L G V SY+ GS +S ++ G
Sbjct: 1195 S---TAEDNGILLYNGDNDH-------IAVELYQGHVRVSYDPGSYPSSAIYSAETINDG 1244
Query: 2511 -VHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADF 2569
HTV L F Q L +D ++ G+ LN + YVGG + N A F
Sbjct: 1245 QFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGM-----PVDVNSAAF 1299
Query: 2570 K-------NGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCGNG 2622
+ GF GCI L + E + P P PC + C +G
Sbjct: 1300 RLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPG---------CEPCRKLYCLHG 1350
Query: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH-GYTCFCPL 2681
+ C+C GW G C + P H H C G C+ L Y+C C
Sbjct: 1351 ICQPNATPGPMCHCEAGWVGLHCDQPAD--GPCHG--HKCVHG-QCVPLDALSYSCQCQD 1405
Query: 2682 GTTGIYCEQALSISDP 2697
G +G C QA ++++P
Sbjct: 1406 GYSGALCNQAGALAEP 1421
Score = 107 bits (268), Expect = 1e-22
Identities = 87/351 (24%), Positives = 131/351 (37%), Gaps = 27/351 (7%)
Query: 123 QLLFGCRLKGMHTVNSKWLSVGTHYFITVMA-----SGPSPCPLGLR-LNVTVKQQFCQE 176
Q L RL +H + L G +T ++ + P C LR L+ VK + +
Sbjct: 829 QGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEP 888
Query: 177 SLSSEFCSG----HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKR 232
++ C+G GK L +K + C P + + + D C PC+N G+C N
Sbjct: 889 GIAR--CAGPQDMEGKLLLTTPAKKFECQGPPTLAVQ--AKCDLCLSSPCQNQGTCHND- 943
Query: 233 ENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNS---FICECDEQFSGP 289
+ Y C C + G++C + C C +G + F C C F GP
Sbjct: 944 ---PLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGP 1000
Query: 290 FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGE--TDVSEFSLVPCQNGTDC 347
C V+ CV G+C + YT +CP + E D+ L PCQ+ C
Sbjct: 1001 TCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQC 1060
Query: 348 IKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE- 406
+ + C C P + C Q C +N A C Y C C G++ + CE
Sbjct: 1061 VGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEI 1120
Query: 407 ---KAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLI 454
C N C + R C+PG C L +V +
Sbjct: 1121 PPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKLLSVNFV 1171
Score = 103 bits (256), Expect = 3e-21
Identities = 95/354 (26%), Positives = 140/354 (39%), Gaps = 47/354 (13%)
Query: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----------HC 2662
C +C NG C++ S C C G+ G C PPH C
Sbjct: 1087 CRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLC----------EIPPHLPAPKSPCEGTEC 1136
Query: 2663 SRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQL 2722
GA C+ + C C G G CE+ LS++ F + +++ F + +I L
Sbjct: 1137 QNGANCVDQGNRPVCQCLPGFGGPECEKLLSVN---FVDRD-TYLQFTDLQNWPRANITL 1192
Query: 2723 QFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGST 2782
Q +GIL Y + D + + L V++ Y+ G TIN
Sbjct: 1193 QVSTAEDNGILLYNGDN------DHIAVELYQGHVRVSYDPGSYPSSA-IYSAETINDGQ 1245
Query: 2783 WHIIKAGRVGAEGYLDLDGIN-VTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEP 2841
+H ++ L +DG + +T K +L++ Y+GG+ VN A
Sbjct: 1246 FHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVD--VNSAAFRLWQ 1303
Query: 2842 V----GFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTF 2897
+ GF GCIR + INN+ T+ K G G C+ C C +G C N T
Sbjct: 1304 ILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPG-CE--PCRKLYCLHG-ICQPNATPG 1359
Query: 2898 S-CRCLPDWAGNTCNQSVS--CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
C C W G C+Q C + C+H C+P + SYSC C G+ G C
Sbjct: 1360 PMCHCEAGWVGLHCDQPADGPCHGHKCVHGQ-CVPLDALSYSCQCQDGYSGALC 1412
Score = 75.5 bits (184), Expect = 8e-13
Identities = 88/346 (25%), Positives = 139/346 (40%), Gaps = 48/346 (13%)
Query: 2084 QGVDTMWTSVSPSVAAP-SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
+G + P + AP S C+ C NG C + G C C F G CEK
Sbjct: 1111 EGYSGQLCEIPPHLPAPKSPCEGTECQNGANC----VDQGNRPV-CQCLPGFGGPECEKL 1165
Query: 2143 AGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLH 2202
+ F + ++YL+ L ++ I L + T NG +LY NG+N +
Sbjct: 1166 LSVNF--VDRDTYLQFTDL------QNWPRANITLQVSTAEDNGILLY-NGDN---DHIA 1213
Query: 2203 LFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADG 2262
+ L +G V Y G+ + SA +IN F + + M+ ++ DG
Sbjct: 1214 VELYQGHVRVSYDPGSYPSSAIYSAE-TINDGQFHTVELVAFDQ--------MVNLSIDG 1264
Query: 2263 KPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVY------GFRGCILDLQVNN 2316
P+ D H + +++G +P V ++ A ++ GF GCI +L +NN
Sbjct: 1265 GSPMTM-DNFGKHYTLNSEAPLYVGGMP--VDVNSAAFRLWQILNGTGFHGCIRNLYINN 1321
Query: 2317 K-EFFIIDEARHG--KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA 2373
+ + F + + G E C +C H +C+ N T C C + G C
Sbjct: 1322 ELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNAT-----PGPMCHCEAGWVGLHCDQP 1376
Query: 2374 S---CENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP 2416
+ C + C +G CVP C C G SG LC A + +P
Sbjct: 1377 ADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALCNQAGALAEP 1421
Score = 72.0 bits (175), Expect = 9e-12
Identities = 77/315 (24%), Positives = 107/315 (33%), Gaps = 89/315 (28%)
Query: 374 CESFPLRNNATCKKCEKD-YPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRF 432
C S P +N TC + Y C+C SG+ ++CE
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCE-------------------------- 962
Query: 433 KYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEK 492
V + C+ PC +N G T H Q+ A F GF EG
Sbjct: 963 --VSLDSCSSGPC---EN-----------GGTCHA--QEGEDAPFTCSCPTGF---EGPT 1001
Query: 493 CQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRY 552
C D +C + A CANG C+ + Y
Sbjct: 1002 CGVNTD-------DCVDHA-----------------------CANGGVCV--DGVGNYTC 1029
Query: 553 LCFLRWAGNM--YLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLG 610
C L++ G L + N CQHEA C + PRC C Y G C N D C
Sbjct: 1030 QCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDC-R 1088
Query: 611 NHSISVHGLCLALSHNCNCSGLQRYERNICEI------DTEDCKSASCKNGTTSTHLRGY 664
+H C+ ++ +C + Y +CEI C+ C+NG
Sbjct: 1089 DHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNR 1148
Query: 665 FFRKCVPGFKGTQCE 679
+C+PGF G +CE
Sbjct: 1149 PVCQCLPGFGGPECE 1163
Score = 68.9 bits (167), Expect = 7e-11
Identities = 45/141 (31%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 1070 DGTSTQCKIKI----NDCTSIPCMNEGFCQKSAH-GFTCICPRGYTGAYCEKSIDNCAEP 1124
D T TQ K + C + C++ G CQ +A G C C G+ G +C++ D
Sbjct: 1325 DFTKTQMKPGVVPGCEPCRKLYCLH-GICQPNATPGPMCHCEAGWVGLHCDQPADGPCHG 1383
Query: 1125 ELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCE---ININECSSSPCLHGADCEDHIN 1181
C++G CV ++ C+C G+SG C C CLHG
Sbjct: 1384 HK----CVHGQ-CVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTK 1438
Query: 1182 GYVCKCQPGWSGHHCENELEC 1202
G C C PG+SG CE E EC
Sbjct: 1439 GAHCVCDPGFSGELCEQESEC 1459
Score = 63.2 bits (152), Expect = 4e-09
Identities = 30/74 (40%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Query: 2339 CAHHLCRNNGTCISDNENLF-CECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTD-- 2393
C C+N GTC +D ++ C CP Y G+ C+ + SC + PC NG TC + G D
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988
Query: 2394 IVCLCPYGRSGPLC 2407
C CP G GP C
Sbjct: 989 FTCSCPTGFEGPTC 1002
Score = 62.4 bits (150), Expect = 7e-09
Identities = 58/249 (23%), Positives = 106/249 (42%), Gaps = 52/249 (20%)
Query: 2882 NTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCT 2940
N C++ +C C C+P +AG+ C+++ C ++ C + + C+ D+ SYSCLC
Sbjct: 1052 NPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCM-DEVNSYSCLCA 1110
Query: 2941 LGWVGRYCENKTSFSTAK----------------------------FMGNSYIKYIDPNY 2972
G+ G+ CE K F G K + N+
Sbjct: 1111 EGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKLLSVNF 1170
Query: 2973 RMRN--LQFT--------TISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAV 3022
R+ LQFT I+L ST + G++++ N +ND +A+ L+ ++++
Sbjct: 1171 VDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLY-----NGDNDHIAVELYQGHVRVSY 1225
Query: 3023 NLGERISVPMS--YNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALN 3080
+ G S P S Y+ T ++H V ++ ++ I+ ++ +D LN
Sbjct: 1226 DPG---SYPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMT--MDNFGKHYTLN 1280
Query: 3081 YDGICYLGG 3089
+ Y+GG
Sbjct: 1281 SEAPLYVGG 1289
Score = 58.5 bits (140), Expect = 1e-07
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 2614 CSLMKCGNGGTC-IESGTSV--YCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
CS C NGGTC + G C+C TG++G C C H C+ G C+
Sbjct: 968 CSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC-----VDHACANGGVCVD 1022
Query: 2671 LPHGYTCFCPLGTTGIYCEQALSISDP 2697
YTC CPL G CEQ + + P
Sbjct: 1023 GVGNYTCQCPLQYEGKACEQLVDLCSP 1049
Score = 55.8 bits (133), Expect = 6e-07
Identities = 46/175 (26%), Positives = 62/175 (35%), Gaps = 26/175 (14%)
Query: 645 EDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDID-ECASHPCKNGATCIDQPGNY 703
E C+ C +G + C G+ G C+ D C H C +G
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHG---------- 1389
Query: 704 FCQCVPPFKVVDGFSCLCNPGYVGIRCEQD---IDDCILNACEHNSTCKDLHLSYQCVCL 760
QCVP + +SC C GY G C Q + C C H CVC
Sbjct: 1390 --QCVPLDAL--SYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCD 1445
Query: 761 SDWEGNFCEQESNECKMNPCKN-------NSTCTDLYKSYRCECTSGWTGQNCSE 808
+ G CEQES EC+ +P ++ + C EC GQ C +
Sbjct: 1446 PGFSGELCEQES-ECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQ 1499
Score = 55.1 bits (131), Expect = 1e-06
Identities = 42/166 (25%), Positives = 61/166 (36%), Gaps = 47/166 (28%)
Query: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEIN-ECDSDPCMNGGLCHESTIPGQF 833
C C+ N+T + C C +GW G +C + + C C++G + +
Sbjct: 1347 CLHGICQPNATPGPM-----CHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDAL--SY 1399
Query: 834 VCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKD 893
C C Y+G C+Q L + PCR
Sbjct: 1400 SCQCQDGYSGALCNQAGALAE----PCRG-----------------------------LQ 1426
Query: 894 CLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKN 939
CL CQ G C+C PGFSG LCE E +EC +P ++
Sbjct: 1427 CLHGHCQASG-----TKGAHCVCDPGFSGELCEQE-SECRGDPVRD 1466
Score = 53.5 bits (127), Expect = 3e-06
Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 7/109 (6%)
Query: 2847 CIRQVIINNQELQLTEFGAKGGSNVGDCDGT--ACGYNTCRNGGECTVN---GTTFSCRC 2901
C Q +N L++ G DC+ + +C C NGG C F+C C
Sbjct: 934 CQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSC 993
Query: 2902 LPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
+ G TC + C+++ C + +C+ D +Y+C C L + G+ CE
Sbjct: 994 PTGFEGPTCGVNTDDCVDHACANGGVCV-DGVGNYTCQCPLQYEGKACE 1041
Score = 53.5 bits (127), Expect = 3e-06
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Query: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
HG C A + CHC+ + G +C D + PC + + D +Y C C
Sbjct: 1349 HGICQPNA-TPGPMCHCEAGWVGLHC---DQPADGPCHGHKCVHGQCVPLDALSYSCQCQ 1404
Query: 246 PPFTGKNCSE---IIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCE 292
++G C++ + C+ C HG+C + C CD FSG CE
Sbjct: 1405 DGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
Score = 50.1 bits (118), Expect = 4e-05
Identities = 36/115 (31%), Positives = 47/115 (40%), Gaps = 11/115 (9%)
Query: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININ-ECSSSPCLHGADCEDHINGYVCKCQP 1189
CL+G IC C C G+ G C+ + C C+HG Y C+CQ
Sbjct: 1347 CLHG-ICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQD 1405
Query: 1190 GWSGHHCENE----LECIPNSCVHELCMEN-EPGSTCLCTPGFMTCSIGLLCGDE 1239
G+SG C C C+H C + G+ C+C PGF G LC E
Sbjct: 1406 GYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFS----GELCEQE 1456
Score = 50.1 bits (118), Expect = 4e-05
Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 43/144 (29%)
Query: 242 CVCHPPFTGKNCSEII-GQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS---AKP 297
C C + G +C + G C H C HG C + + S+ C+C + +SG C + A+P
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEP 1421
Query: 298 CVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCI 357
C RG+ +C G +G + C+
Sbjct: 1422 C-------RGL----------QCLHGHCQASG---------------------TKGAHCV 1443
Query: 358 CSPIFTDLLCKSIQTSCESFPLRN 381
C P F+ LC+ ++ C P+R+
Sbjct: 1444 CDPGFSGELCEQ-ESECRGDPVRD 1466
Score = 45.8 bits (107), Expect = 7e-04
Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 18/144 (12%)
Query: 186 HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCH 245
HG+C+ + +YSC CQ +SG C + A + +PC+ + + CVC
Sbjct: 1388 HGQCVPLD-ALSYSCQCQDGYSGALCNQAGALA-EPCRGLQCLHGHCQASGTKGAHCVCD 1445
Query: 246 PPFTGKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEVS--AKPCVSL 301
P F+G+ C E +C+ P FH + IC+ S C S + C
Sbjct: 1446 PGFSGELC-EQESECRGDPVRDFH----QVQRGYAICQTTRPLSWVECRGSCPGQGCCQG 1500
Query: 302 LFWKRGICPNSSSAYTYECPKGSS 325
L KR +T+EC G+S
Sbjct: 1501 LRLKR-------RKFTFECSDGTS 1517
Score = 40.0 bits (92), Expect = 0.036
Identities = 55/268 (20%), Positives = 104/268 (38%), Gaps = 30/268 (11%)
Query: 1891 DSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYC 1950
D+YL+F ++ P+ NI+L+ T G+LLY + ++ ++L+ + + Y
Sbjct: 1174 DTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIA----VELYQGHVRVSYD--- 1226
Query: 1951 PGEAKFKSINTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESI--NHVLGKPLP 2008
PG +I + +++GQ +T+ + N L+I G + ++ ++ L P
Sbjct: 1227 PGSYPSSAIYSAETINDGQFHTVELVAFDQMVN--LSIDGGSPMTMDNFGKHYTLNSEAP 1284
Query: 2009 KSGSVFIGGFP-DLHG---KIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCR 2064
+++GG P D++ ++ + F GCI + INN +K + C
Sbjct: 1285 ----LYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGC- 1339
Query: 2065 SQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSV-CQQDV---CHNGGTCHAIFLS 2120
P + Q T + C Q CH H +
Sbjct: 1340 ------EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVP 1393
Query: 2121 SGIVSFQCDCPLHFTGRFCEKDAGLFFP 2148
+S+ C C ++G C + L P
Sbjct: 1394 LDALSYSCQCQDGYSGALCNQAGALAEP 1421
Score = 39.7 bits (91), Expect = 0.048
Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFN 2151
C C NGG C G+ ++ C CPL + G+ CE+ L P N
Sbjct: 1009 CVDHACANGGVC-----VDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Score = 35.8 bits (81), Expect = 0.69
Identities = 16/37 (43%), Positives = 16/37 (43%), Gaps = 2/37 (5%)
Query: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
C C NGGTCHA F C CP F G C
Sbjct: 968 CSSGPCENGGTCHA--QEGEDAPFTCSCPTGFEGPTC 1002
Score = 33.9 bits (76), Expect = 2.6
Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 4/39 (10%)
Query: 2102 VCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
+C C N GTCH + + ++C CP + GR CE
Sbjct: 928 LCLSSPCQNQGTCH----NDPLEVYRCACPSGYKGRDCE 962
Score = 33.1 bits (74), Expect = 4.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 2916 CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
CL++ C +Q C D Y C C G+ GR CE
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCE 962
Score = 32.7 bits (73), Expect = 5.8
Identities = 33/128 (25%), Positives = 46/128 (35%), Gaps = 21/128 (16%)
Query: 175 QESLSSEFCSG----HGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCIN 230
Q +E C G HG C + +K C C P FSG+ C++ C P ++
Sbjct: 1414 QAGALAEPCRGLQCLHGHCQASG-TKGAHCVCDPGFSGELCEQESECRGDPVRDFHQV-- 1470
Query: 231 KRENWDEQAYE-CVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
++ Y C P + C G C C G + F EC + S
Sbjct: 1471 ------QRGYAICQTTRPLSWVECR---GSCPGQGCCQG--LRLKRRKFTFECSDGTS-- 1517
Query: 290 FCEVSAKP 297
F E KP
Sbjct: 1518 FAEEVEKP 1525
Score = 32.0 bits (71), Expect = 9.9
Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 8/112 (7%)
Query: 2611 ASPCSLMKCGNGGTCIESGTS-VYCNCTTGWKGSFCTETVSTC--DPEHDPPHHCSRG-A 2666
A PC ++C +G C SGT +C C G+ G C E S C DP D H RG A
Sbjct: 1419 AEPCRGLQCLHGH-CQASGTKGAHCVCDPGFSGELC-EQESECRGDPVRD-FHQVQRGYA 1475
Query: 2667 TCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKT 2718
C + C G C Q L + F SFA V K T
Sbjct: 1476 ICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAE-EVEKPT 1526
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 168 bits (426), Expect = 7e-41
Identities = 160/561 (28%), Positives = 239/561 (42%), Gaps = 88/561 (15%)
Query: 682 IDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGY----VGIRCEQDIDDC 737
ID CA+ GAT + PG CV + DG+ C+C+PGY C D ++C
Sbjct: 845 IDRCAA-----GATNVCGPGT----CV---NLPDGYRCVCSPGYQLHPSQAYCTDD-NEC 891
Query: 738 ILNACEHNSTCKDLHLSYQCVCLSDW----EGNFCE-QESNECKMNPCKNNSTCTDLYKS 792
+ + C+ C + SY C C + G E Q+ NEC+ + CT+ S
Sbjct: 892 LRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGS 951
Query: 793 YRCECTSGW--TGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCL-CPPLYTGQFCHQR 849
Y CEC G+ + ++INEC G C S PG + CL C Y G Q
Sbjct: 952 YHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNS--PGSYTCLACEEGYRG----QS 1005
Query: 850 YNLCDLLHNPCRNNSTC----LALVDANQHCICREEFE----GKNCEIDVKDCLFLSCQD 901
+ D+ N C C ++ + C C + +E K C+ DV +C +
Sbjct: 1006 GSCVDV--NECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQ-DVDECASRASCP 1062
Query: 902 YGDCEDMVNNFRC-ICRPGF----SGSLCEIEINECSSEPCKNNGTCVDLTNRFFC-NCE 955
G C + +F C C G+ G+ CE +++EC+ +G C + F C +C+
Sbjct: 1063 TGLCLNTEGSFACSACENGYWVNEDGTACE-DLDECAFPGVCPSGVCTNTAGSFSCKDCD 1121
Query: 956 PEYH----GPFCELDVNKCK--ISPCLDEENCVYRTDGYNCLCAPGY---TGINCEINLD 1006
Y G CE DV++C+ S CL E C Y CLC G+ G CE +++
Sbjct: 1122 GGYRPSPLGDSCE-DVDECEDPQSSCLGGE-CKNTVGSYQCLCPQGFQLANGTVCE-DVN 1178
Query: 1007 ECLSEP-CLHDGVCIDGINHYTCDCKSGFF----GTHCETNANDCLSNPCLHGRCTELIN 1061
EC+ E C G C++ + C C GF GT C+ ++PC+ G C
Sbjct: 1179 ECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEG 1238
Query: 1062 EYPCSCDA----DGTSTQCKIKINDCTSI--PCMNEGFCQKSAHGFTCI--CPRGYTGAY 1113
+ C C+ S +C + I++C P C+ S + C+ C G+ A
Sbjct: 1239 SFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAP 1297
Query: 1114 CEK--SIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF----SGQFCEININECSS 1167
ID CA N +C + G C D +F C C GF SG C +++NEC
Sbjct: 1298 NGDCIDIDECA----NDTMCGSHGFC-DNTDGSFRCLCDQGFEISPSGWDC-VDVNECEL 1351
Query: 1168 SPCLHGAD-CEDHINGYVCKC 1187
+ GA CE+ ++C C
Sbjct: 1352 MLAVCGAALCENVEGSFLCLC 1372
Score = 157 bits (398), Expect = 1e-37
Identities = 112/372 (30%), Positives = 172/372 (46%), Gaps = 48/372 (12%)
Query: 903 GDCEDMVNNFRCICRPGF----SGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEY 958
G C ++ + +RC+C PG+ S + C + NEC +PCK G C++ + C C P Y
Sbjct: 859 GTCVNLPDGYRCVCSPGYQLHPSQAYCTDD-NECLRDPCKGKGRCINRVGSYSCFCYPGY 917
Query: 959 ----HGPFCEL-DVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGI---NCEINLDECLS 1010
G E D+N+C+ C Y+C C GY + +C+ +++EC
Sbjct: 918 TLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQ-DINECRH 976
Query: 1011 EPCLHDGVCIDGINHYTC-DCKSGFFGTHCE-TNANDCLS-NPCLHGRCTELINEYPCSC 1067
DG C++ YTC C+ G+ G + N+CL+ C HG+CT L + CSC
Sbjct: 977 PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSC 1036
Query: 1068 DADGTSTQ----CKIKINDCTSIPCMNEGFCQKSAHGFTC-ICPRGY----TGAYCEKSI 1118
+ T C+ +++C S G C + F C C GY G CE +
Sbjct: 1037 EQGYEVTSDEKGCQ-DVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACE-DL 1094
Query: 1119 DNCAEPELNSVICLNGGICVDGPGHTFDCR-CLPGFS----GQFCEININECS--SSPCL 1171
D CA P +C G+C + G +F C+ C G+ G CE +++EC S CL
Sbjct: 1095 DECAFPG----VC-PSGVCTNTAG-SFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCL 1147
Query: 1172 HGADCEDHINGYVCKCQPGW---SGHHCENELECI--PNSCVHELCMENEPGSTCLCTPG 1226
G +C++ + Y C C G+ +G CE+ EC+ + H C+ + CLC PG
Sbjct: 1148 -GGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPG 1206
Query: 1227 FMTCSIGLLCGD 1238
F++ G C D
Sbjct: 1207 FVSAEGGTSCQD 1218
Score = 157 bits (397), Expect = 2e-37
Identities = 174/705 (24%), Positives = 266/705 (37%), Gaps = 169/705 (23%)
Query: 669 CVPGFKGTQCEI---DIDECASHPCKNGATCIDQPGNYFCQCVPPFKVV----------- 714
C PG++ + D +EC PCK CI++ G+Y C C P + +
Sbjct: 872 CSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDI 931
Query: 715 ------------------DGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHL--- 753
+ C C+ GY+ +R D +N C H TC D
Sbjct: 932 NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQD---INECRHPGTCPDGRCVNS 988
Query: 754 --SYQCV-CLSDWEGNFCE-QESNECKMNPCKNNSTCTDLYKSYRCECTSGW---TGQNC 806
SY C+ C + G + NEC + CT+L S+RC C G+ + +
Sbjct: 989 PGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKG 1048
Query: 807 SEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTC 866
++++EC S GLC + G F C G + ++ C+ L + C C
Sbjct: 1049 CQDVDECASRASCPTGLCLNT--EGSFA--CSACENGYWVNEDGTACEDL-DECAFPGVC 1103
Query: 867 LALVDANQHCICREEFEGKNCEIDVKDC-LFLSCQDYGDCED------------MVNNFR 913
+ V N F K+C+ + L SC+D +CED V +++
Sbjct: 1104 PSGVCTN----TAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQ 1159
Query: 914 CICRPGF---SGSLCEIEINEC-SSEPCKNNGTCVDLTNRFFCNCEPEY----HGPFCEL 965
C+C GF +G++CE ++NEC E C +G C++ FFC C P + G C+
Sbjct: 1160 CLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQ- 1217
Query: 966 DVNKCKIS-PCLDEENCVYRTDGYNCLCAPGY----TGINCEINLDEC--LSEPCLHDGV 1018
DV++C + PC+ +CV +NCLC G+ C +++DEC +P
Sbjct: 1218 DVDECATTDPCVG-GHCVNTEGSFNCLCETGFQPSPESGEC-VDIDECEDYGDPVCGTWK 1275
Query: 1019 CIDGINHYTC--DCKSGFFGTHCETNANDCLS-NPCL-------HGRCTELINEYPCSCD 1068
C + Y C C+ GF H N DC+ + C HG C + C CD
Sbjct: 1276 CENSPGSYRCVLGCQPGF---HMAPN-GDCIDIDECANDTMCGSHGFCDNTDGSFRCLCD 1331
Query: 1069 ----ADGTSTQCKIKINDC-TSIPCMNEGFCQKSAHGFTCIC---------------PRG 1108
+ C + +N+C + C+ F C+C PRG
Sbjct: 1332 QGFEISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRG 1390
Query: 1109 YTGAYCEKSIDNCAEPELNSVICLNG----GICVDGPGHT---FDCRCLPGFS-GQFCEI 1160
G ++ P + C +G C G +C C G S G C++
Sbjct: 1391 AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDL 1450
Query: 1161 NINECS---SSPCLHG-------------------AD--------------CEDHINGYV 1184
+E S S C G AD C + + GYV
Sbjct: 1451 CPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYV 1510
Query: 1185 CKCQPGW----SGHHCENELECIPNSCVHELCMENEPGSTCLCTP 1225
C C PG+ S CE+ EC +C + C+ E C C+P
Sbjct: 1511 CLCNPGFHYDASHKKCEDHDECQDLACENGECVNTEGSFHCFCSP 1555
Score = 154 bits (388), Expect = 2e-36
Identities = 138/501 (27%), Positives = 199/501 (39%), Gaps = 62/501 (12%)
Query: 785 TCTDLYKSYRCECTSGWT---GQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLY 841
TC +L YRC C+ G+ Q + NEC DPC G C G + C C P Y
Sbjct: 860 TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRV--GSYSCFCYPGY 917
Query: 842 TGQFCHQRYNLCDLLHNPCRNNSTC----LALVDANQHCICREEF---EGKNCEIDVKDC 894
T D+ N C C + + HC C + + +C+ D+ +C
Sbjct: 918 TLATSGATQECQDI--NECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQ-DINEC 974
Query: 895 LFLSCQDYGDCEDMVNNFRCI-CRPGFSGSLCE-IEINECSSEPCKNNGTCVDLTNRFFC 952
G C + ++ C+ C G+ G +++NEC + +G C +L F C
Sbjct: 975 RHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRC 1034
Query: 953 NCEPEYHGPFCEL---DVNKCKISPCLDEENCVYRTDGYNC-LCAPGY----TGINCEIN 1004
+CE Y E DV++C C+ + C C GY G CE +
Sbjct: 1035 SCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACE-D 1093
Query: 1005 LDECLSEPCLHDGVCIDGINHYTC-DCKSGF----FGTHCETNANDCLS--NPCLHGRCT 1057
LDEC GVC + ++C DC G+ G CE + ++C + CL G C
Sbjct: 1094 LDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCLGGECK 1152
Query: 1058 ELINEYPCSCDAD---GTSTQCKIKINDCTSIP-CMNEGFCQKSAHGFTCICPRGYT--- 1110
+ Y C C T C+ +N+C C G C S F C+C G+
Sbjct: 1153 NTVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAE 1211
Query: 1111 -GAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF-----SGQFCEININE 1164
G C+ +D CA + C+ GG CV+ G +F+C C GF SG+ +I+ E
Sbjct: 1212 GGTSCQ-DVDECATTDP----CV-GGHCVNTEG-SFNCLCETGFQPSPESGECVDIDECE 1264
Query: 1165 CSSSPCLHGADCEDHINGYVCK--CQPGWS---GHHCENELECIPNSCV--HELCMENEP 1217
P CE+ Y C CQPG+ C + EC ++ H C +
Sbjct: 1265 DYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDG 1324
Query: 1218 GSTCLCTPGFMTCSIGLLCGD 1238
CLC GF G C D
Sbjct: 1325 SFRCLCDQGFEISPSGWDCVD 1345
Score = 144 bits (364), Expect = 1e-33
Identities = 260/1122 (23%), Positives = 396/1122 (35%), Gaps = 255/1122 (22%)
Query: 210 YCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPF----------TGKNCSEIIGQ 259
+CQ+++ C + C+N R + Y C C P + K S + G
Sbjct: 619 HCQDINECLTLGLCKDAECVNTRGS-----YLCTCRPGLMLDPSRSRCVSDKAISMLQGL 673
Query: 260 CQ----PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSA 315
C P C IT C + G CE P R ICP +
Sbjct: 674 CYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAF---REICP-AGHG 729
Query: 316 YTYECPKGSSSQNGETDVSEFSLVPCQNGTDC------------IKISNDVMCICS--PI 361
YTY S + + E + P + G +++ D P
Sbjct: 730 YTYASSDIRLSMR-KAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPD 788
Query: 362 FTDLLCKSIQTSCESFP--LRNNATCKKCEKDYPCSCISGFTEKNCEKA----------- 408
D + TS P + NAT P I+ E+ +
Sbjct: 789 KGDSQAGQVTTSVTHAPAWVTGNATTPPM----PEQGIAEIQEEQVTPSTDVLVTLSTPG 844
Query: 409 IDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYC---GVTF 465
ID C + N C N+ ++ VC PG Y +H YC
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPG------------YQLHPSQAYCTDDNECL 892
Query: 466 HGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCW 525
C+ KG + GS C Y + T++ +N+ E
Sbjct: 893 RDPCKGKGRC-------INRVGSYSCFC---YPGYTLATSGATQECQDINECEQPG---- 938
Query: 526 FPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDE- 584
+C+ G C + E S Y C G + + NEC+H C D
Sbjct: 939 --------VCSGG-QCTNTEGS--YHCECD---QGYIMVRKGHCQDINECRHPGTCPDGR 984
Query: 585 -INRPR----CSCSLSYIGRL-CVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERN 638
+N P +C Y G+ V+V+ CL + HG C L + CS Q YE
Sbjct: 985 CVNSPGSYTCLACEEGYRGQSGSCVDVNECL-TPGVCAHGKCTNLEGSFRCSCEQGYEVT 1043
Query: 639 ICE---IDTEDCKS-ASCKNGTTSTHLRGYFFRKCVPGF----KGTQCEIDIDECASHPC 690
E D ++C S ASC G + C G+ GT CE D+DECA
Sbjct: 1044 SDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACE-DLDECAFPGV 1102
Query: 691 KNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDC--ILNACEHNSTC 748
C + G++ C K DG P +G CE D+D+C ++C C
Sbjct: 1103 CPSGVCTNTAGSFSC------KDCDGG---YRPSPLGDSCE-DVDECEDPQSSC-LGGEC 1151
Query: 749 KDLHLSYQCVCLSDWE---GNFCEQESNECK-MNPCKNNSTCTDLYKSYRCECTSGWT-- 802
K+ SYQC+C ++ G CE + NEC C + C + + S+ C C G+
Sbjct: 1152 KNTVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSA 1210
Query: 803 -GQNCSEEINEC-DSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPC 860
G ++++EC +DPC+ G H G F CLC TG P
Sbjct: 1211 EGGTSCQDVDECATTDPCVGG---HCVNTEGSFNCLCE---TG-------------FQPS 1251
Query: 861 RNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGD-------CEDMVNNFR 913
+ C+ +ID C+DYGD CE+ ++R
Sbjct: 1252 PESGECV--------------------DID-------ECEDYGDPVCGTWKCENSPGSYR 1284
Query: 914 CI--CRPGF----SGSLCEIEINECSSEP-CKNNGTCVDLTNRFFCNCEPEYH----GPF 962
C+ C+PGF +G I+I+EC+++ C ++G C + F C C+ + G
Sbjct: 1285 CVLGCQPGFHMAPNGDC--IDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWD 1342
Query: 963 CELDVNKCKISPCLDEENCVYRTDG-YNCLCAPGYTGINCEINLDECLSEPCLHDGVCID 1021
C +DVN+C++ + +G + CLCA L E +G C
Sbjct: 1343 C-VDVNECELMLAVCGAALCENVEGSFLCLCASD-------------LEEYDAQEGHCRP 1388
Query: 1022 -GINHYTCDCKSGFFGTHCETNAN-DCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIK 1079
G + G H DC S H C+ ++ + A+ TQ
Sbjct: 1389 RGAGGQS--MSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRN--TTQAECCCTQGASW 1444
Query: 1080 INDCTSIPCMNEGFCQKSAHGFTCICP--RGYTGAYCEKSIDNCAEPELNSVICLNGGIC 1137
+ C P + + F+ ICP +GY + + + + G+C
Sbjct: 1445 GDACDLCP-------SEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLC 1497
Query: 1138 VDG------PGHTFDCRCLPGF----SGQFCEININECSSSPCLHGADCEDHINGYVCKC 1187
+G PG+ C C PGF S + CE + +EC C +G +C + + C C
Sbjct: 1498 PNGRCLNTVPGYV--CLCNPGFHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFC 1553
Query: 1188 QP----GWSGHHCEN---ELECIPNSCVH-ELCMENEPGSTC 1221
P S C N E +P+ +H ++C + C
Sbjct: 1554 SPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVC 1595
Score = 127 bits (318), Expect = 2e-28
Identities = 205/899 (22%), Positives = 317/899 (35%), Gaps = 236/899 (26%)
Query: 131 KGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSSEFCSGHGKCL 190
+G+ + + ++ T +T+ G C G ++ C G G C+
Sbjct: 820 QGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAG----------------ATNVC-GPGTCV 862
Query: 191 SEAWSKTYSCHCQPPF----SGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHP 246
+ Y C C P + S YC + + C PCK G CIN+ +Y C C+P
Sbjct: 863 N--LPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINR-----VGSYSCFCYP 915
Query: 247 PFT------GKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQF---SGPFCEVSAKP 297
+T + C +I QP VC G C+N T S+ CECD+ + C+
Sbjct: 916 GYTLATSGATQECQDINECEQPGVCSGGQCTN-TEGSYHCECDQGYIMVRKGHCQ-DINE 973
Query: 298 CVSLLFWKRGICPNSSSAYT-YECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMC 356
C G C NS +YT C +G Q+G C + +C+
Sbjct: 974 CRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGS----------CVDVNECLTPG----- 1018
Query: 357 ICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF----TEKNCEKAIDHC 412
+C+ + C E + CSC G+ EK C+ +D C
Sbjct: 1019 VCA----------------------HGKCTNLEGSFRCSCEQGYEVTSDEKGCQD-VDEC 1055
Query: 413 KLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYC---------GV 463
S C N G F C +N Y +++ C GV
Sbjct: 1056 --ASRASCPTGLCLNTEGSF-----------ACSACENGYWVNEDGTACEDLDECAFPGV 1102
Query: 464 TFHGICQDKGPAQFEYVWQLGFAGSEGEK-CQGVIDAYFFLAANCTEDATYVNDPEDNNS 522
G+C + AGS K C G + + + V++ ED S
Sbjct: 1103 CPSGVCTNT-------------AGSFSCKDCDG-----GYRPSPLGDSCEDVDECEDPQS 1144
Query: 523 SCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHE---- 578
SC G C + S Y+ LC G T + NEC E
Sbjct: 1145 SCL------------GGECKNTVGS--YQCLC---PQGFQLANGTVCEDVNECMGEEHCA 1187
Query: 579 --AVCKDEINRPRCSCSLSYI----GRLC-----VVNVDYCLGNHSISVHGLCLALSHNC 627
C + C C+ ++ G C D C+G H ++ G S NC
Sbjct: 1188 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEG-----SFNC 1242
Query: 628 NC-SGLQRYERNICEIDTEDCK--------SASCKNGTTSTHLRGYFFRKCVPGF---KG 675
C +G Q + +D ++C+ + C+N S C PGF
Sbjct: 1243 LCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRC----VLGCQPGFHMAPN 1298
Query: 676 TQCEIDIDECASHP-CKNGATCIDQPGNYFCQCVPPFKV-VDGFSCLCNPGYVGIRCEQD 733
C IDIDECA+ C + C + G++ C C F++ G+ C+ D
Sbjct: 1299 GDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCV------------D 1345
Query: 734 IDDC-ILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNS-----TCT 787
+++C ++ A + C+++ S+ C+C SD E + + C+ S T
Sbjct: 1346 VNECELMLAVCGAALCENVEGSFLCLCASDLEE--YDAQEGHCRPRGAGGQSMSEAPTGD 1403
Query: 788 DLYKSYRCECTSGWTGQ-NCSEEI--NECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQ 844
R +C SG G CS + N ++ C C + G LCP + +
Sbjct: 1404 HAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECC-----CTQGASWGDACDLCPSEDSAE 1458
Query: 845 FCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLS---CQD 901
F C + + + A G+ D +C+ C +
Sbjct: 1459 F-----------SEICPSGKGYIPVEGAWTF--------GQTMYTDADECVIFGPGLCPN 1499
Query: 902 YGDCEDMVNNFRCICRPGF----SGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEP 956
G C + V + C+C PGF S CE + +EC C+ NG CV+ F C C P
Sbjct: 1500 -GRCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACE-NGECVNTEGSFHCFCSP 1555
Score = 97.4 bits (241), Expect = 2e-19
Identities = 217/998 (21%), Positives = 343/998 (34%), Gaps = 243/998 (24%)
Query: 307 GICPNSSSAYTYECPKGSS---SQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFT 363
G C N Y C G SQ TD +E PC+ CI C C P +T
Sbjct: 859 GTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYT 918
Query: 364 DLLCKSIQ-----TSCESFPLRNNATCKKCEKDYPCSCISGF--TEKNCEKAIDHCKLLS 416
+ Q CE + + C E Y C C G+ K + I+ C+
Sbjct: 919 LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECR--H 976
Query: 417 INCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQ 476
+ C N G Y C+ C + + +++ L GV HG C +
Sbjct: 977 PGTCPDGRCVNSPG--SYTCL-ACEEGYRGQSGSCVDVNECLTP-GVCAHGKCTNL-EGS 1031
Query: 477 FEYVWQLGFAGSEGEK-CQGV--------------IDAYFFLAANCTEDATYVNDPE--- 518
F + G+ + EK CQ V ++ A + E+ +VN+
Sbjct: 1032 FRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTAC 1091
Query: 519 DNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHE 578
++ C FP +C N S +D C + + ++ D E E
Sbjct: 1092 EDLDECAFPGVCPSGVCTNTAGSFSCKD-------CDGGYRPSPLGDSCEDVDECEDPQS 1144
Query: 579 AV----CKDEINRPRCSCSLSYI---GRLCVVNVDYCLGNHSISVHGLCLALSHN---CN 628
+ CK+ + +C C + G +C +V+ C+G + HG CL SH C
Sbjct: 1145 SCLGGECKNTVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLN-SHGSFFCL 1202
Query: 629 CS-GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGT----QCEIDID 683
C+ G E D ++C + G + G F C GF+ + +C +DID
Sbjct: 1203 CAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGEC-VDID 1261
Query: 684 ECASH--PCKNGATCIDQPGNYFCQ--CVPPFKVV------------------------- 714
EC + P C + PG+Y C C P F +
Sbjct: 1262 ECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDN 1321
Query: 715 -DG-FSCLCNPGYV----GIRCEQDIDDC-ILNACEHNSTCKDLHLSYQCVCLSDWE--- 764
DG F CLC+ G+ G C D+++C ++ A + C+++ S+ C+C SD E
Sbjct: 1322 TDGSFRCLCDQGFEISPSGWDCV-DVNECELMLAVCGAALCENVEGSFLCLCASDLEEYD 1380
Query: 765 -----------GNFCEQESNECKMNPCKNNSTCTDLYKSY--------------RCECTS 799
G E+ P C K + C CT
Sbjct: 1381 AQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQ 1440
Query: 800 GWT-GQNC-------SEEINEC----------------------DSDPCM--NGGLCHE- 826
G + G C S E +E D+D C+ GLC
Sbjct: 1441 GASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG 1500
Query: 827 ---STIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFE 883
+T+PG +VCLC P + H++ D + N C+ + + HC C
Sbjct: 1501 RCLNTVPG-YVCLCNPGFHYDASHKKCEDHDECQDLACENGECVN-TEGSFHCFCSPPL- 1557
Query: 884 GKNCEIDVKDCL--FLSCQDYGD----------------CEDMVNNFR-----CICRPGF 920
++ + C+ S +D D C + + R C C+ G
Sbjct: 1558 --TLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGE 1615
Query: 921 SGS----LCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEY-HGPFCELDVNKCKISPC 975
+ S LC +E ++ C N ++ + P Y +GP +
Sbjct: 1616 AWSQQCALCPPRSSEVYAQLC--NVARIEAEREAGVHFRPGYEYGPGPD----------- 1662
Query: 976 LDEENCVYRTDGYNCLCAPGYTGINCEINLDECL----------SEPCLHDGVCIDGIN- 1024
D +Y DG AP Y + E + E P L + +
Sbjct: 1663 -DLHYSIYGPDG-----APFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQP 1716
Query: 1025 HYTC---DCKSGFFGTHCETNANDC-LSNPCLHGRCTELINEYPCSC----DADGTSTQC 1076
HY + +GF G E +C + N C +GRC + Y C C D C
Sbjct: 1717 HYVASHPEPPAGFEGLQAE----ECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMAC 1772
Query: 1077 KIKINDC-----TSIPCMNEGFCQKSAHGFTCICPRGY 1109
+ +N+C ++ C++ G+C+ + + C C GY
Sbjct: 1773 -VDVNECDDLNGPAVLCVH-GYCENTEGSYRCHCSPGY 1808
Score = 42.4 bits (98), Expect = 0.007
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 186 HGKCLSEAWSKTYSCHCQPPF----SGKYCQELDACSFKPCKNNGSCINKRENWDEQAYE 241
+G+CL+ Y C C P F S K C++ D C C+N G C+N E ++
Sbjct: 1499 NGRCLNTV--PGYVCLCNPGFHYDASHKKCEDHDECQDLACEN-GECVNT-----EGSFH 1550
Query: 242 CVCHPPFT 249
C C PP T
Sbjct: 1551 CFCSPPLT 1558
Score = 37.0 bits (84), Expect = 0.31
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 17/137 (12%)
Query: 992 CAPGYTGIN---CEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLS 1048
C GY +N C+ +++ECL+ D C++ Y C C+ G + + + C+S
Sbjct: 608 CPQGYKRLNLTHCQ-DINECLTLGLCKDAECVNTRGSYLCTCRPGLM---LDPSRSRCVS 663
Query: 1049 NPC---LHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQK----SAHGF 1101
+ L G C + C+ T+ +I C+ + C+K F
Sbjct: 664 DKAISMLQGLCYRSLGPGTCTLPLAQRITK---QICCCSRVGKAWGSECEKCPLPGTEAF 720
Query: 1102 TCICPRGYTGAYCEKSI 1118
ICP G+ Y I
Sbjct: 721 REICPAGHGYTYASSDI 737
Score = 34.7 bits (78), Expect = 1.5
Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 5/31 (16%)
Query: 817 PCMNGGLCHESTIPGQFVCLCPPLYTGQFCH 847
PC+NGG C G+ C CP TG+FCH
Sbjct: 403 PCLNGGRCI-----GRDECWCPANSTGKFCH 428
Score = 34.3 bits (77), Expect = 2.0
Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 5/75 (6%)
Query: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLN-NLCLHQSLCIPDQ-- 2931
D C + C+ G C ++SC C P + T + C + N C +C Q
Sbjct: 887 DDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCT 946
Query: 2932 --SFSYSCLCTLGWV 2944
SY C C G++
Sbjct: 947 NTEGSYHCECDQGYI 961
Score = 34.3 bits (77), Expect = 2.0
Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 17/85 (20%)
Query: 771 ESNECK-MNPCKNNSTCTDLYKSYRCECTSGW---TGQNCSEEINECDSDPCMNG----- 821
++ EC +N C+N C + + Y C+C G+ ++NECD +NG
Sbjct: 1733 QAEECGILNGCENGR-CVRVREGYTCDCFEGFQLDAAHMACVDVNECDD---LNGPAVLC 1788
Query: 822 --GLCHESTIPGQFVCLCPPLYTGQ 844
G C + G + C C P Y +
Sbjct: 1789 VHGYCENT--EGSYRCHCSPGYVAE 1811
Score = 33.9 bits (76), Expect = 2.6
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 16/86 (18%)
Query: 1152 GFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGW---SGHH-CENELECIPNS- 1206
G + C I +N C + C+ + GY C C G+ + H C + EC +
Sbjct: 1731 GLQAEECGI-LNGCENGRCVRVRE------GYTCDCFEGFQLDAAHMACVDVNECDDLNG 1783
Query: 1207 ----CVHELCMENEPGSTCLCTPGFM 1228
CVH C E C C+PG++
Sbjct: 1784 PAVLCVHGYCENTEGSYRCHCSPGYV 1809
Score = 33.5 bits (75), Expect = 3.4
Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 5/71 (7%)
Query: 2623 GTCIESGTSVYC-NCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPL 2681
G C + S C +C G++ S ++ D DP C G C + Y C CP
Sbjct: 1106 GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCL-GGECKNTVGSYQCLCPQ 1164
Query: 2682 G---TTGIYCE 2689
G G CE
Sbjct: 1165 GFQLANGTVCE 1175
Score = 32.7 bits (73), Expect = 5.8
Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 779 PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP 817
PC+N +C+ + C C SG+ G C E I + + DP
Sbjct: 194 PCQNRGSCS---RPQLCVCRSGFRGARCEEVIPDEEFDP 229
Score = 32.3 bits (72), Expect = 7.6
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 668 KCVPGFKG---TQCEIDIDECASHPCKNGATCIDQPGNYFCQCVP 709
+C G+K T C+ DI+EC + A C++ G+Y C C P
Sbjct: 607 ECPQGYKRLNLTHCQ-DINECLTLGLCKDAECVNTRGSYLCTCRP 650
Score = 32.0 bits (71), Expect = 9.9
Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 4/50 (8%)
Query: 992 CAPGYTGINCEINLDECLSEP-CLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
C PG+T N + + + EP C + G C C C+SGF G CE
Sbjct: 173 CCPGWTTANSTNHCIKPVCEPPCQNRGSCS---RPQLCVCRSGFRGARCE 219
Score = 32.0 bits (71), Expect = 9.9
Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 3/32 (9%)
Query: 1087 PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
PC N G C + C+C G+ GA CE+ I
Sbjct: 194 PCQNRGSCSRPQ---LCVCRSGFRGARCEEVI 222
Score = 32.0 bits (71), Expect = 9.9
Identities = 21/80 (26%), Positives = 31/80 (38%), Gaps = 12/80 (15%)
Query: 2875 DGTAC-------GYNTCRNGGECTVNGTTFSCRCLPDW----AGNTCNQSVSCLNNLCLH 2923
+GT C G C GEC + +F C C P + G +C C
Sbjct: 1170 NGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCV 1229
Query: 2924 QSLCIPDQSFSYSCLCTLGW 2943
C+ + S++CLC G+
Sbjct: 1230 GGHCVNTEG-SFNCLCETGF 1248
Score = 32.0 bits (71), Expect = 9.9
Identities = 20/87 (22%), Positives = 29/87 (33%), Gaps = 4/87 (4%)
Query: 2599 HPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWK---GSFCTETVSTCDPE 2655
HP A C ++ G C+ C+C G++ V+ CD
Sbjct: 1722 HPEPPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDL 1781
Query: 2656 HDPPHHCSRGATCISLPHGYTCFCPLG 2682
+ P C G C + Y C C G
Sbjct: 1782 NGPAVLCVHG-YCENTEGSYRCHCSPG 1807
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 132,885,776
Number of Sequences: 37866
Number of extensions: 6736256
Number of successful extensions: 38233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 181
Number of HSP's successfully gapped in prelim test: 263
Number of HSP's that attempted gapping in prelim test: 13353
Number of HSP's gapped (non-prelim): 10001
length of query: 3144
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3023
effective length of database: 13,665,732
effective search space: 41311507836
effective search space used: 41311507836
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.