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Search of human proteins with 221625422
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
sapiens]
(1015 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 2071 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 2056 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 1410 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 1327 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 1319 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 1253 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 1221 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1177 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1175 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1139 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 1097 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 1027 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 934 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 925 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 798 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 759 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 737 0.0
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 555 e-158
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 318 2e-86
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 236 1e-61
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens] 236 1e-61
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 229 1e-59
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 226 6e-59
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 226 6e-59
gi|4503787 fyn-related kinase [Homo sapiens] 223 7e-58
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 223 9e-58
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 222 1e-57
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 222 1e-57
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 222 2e-57
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 221 4e-57
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 2071 bits (5367), Expect = 0.0
Identities = 1015/1015 (100%), Positives = 1015/1015 (100%)
Query: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
Sbjct: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
Query: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
Sbjct: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
Query: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
Sbjct: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
Query: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
Sbjct: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
Query: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
Sbjct: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
Query: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
Sbjct: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
Query: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
Sbjct: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
Query: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
Sbjct: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
Query: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
Sbjct: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
Query: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGRRCG 600
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGRRCG
Sbjct: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGRRCG 600
Query: 601 YSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIG 660
YSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIG
Sbjct: 601 YSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIG 660
Query: 661 AGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGV 720
AGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGV
Sbjct: 661 AGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGV 720
Query: 721 VTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLA 780
VTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLA
Sbjct: 721 VTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLA 780
Query: 781 ARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVW 840
ARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVW
Sbjct: 781 ARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVW 840
Query: 841 SYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSR 900
SYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSR
Sbjct: 841 SYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSR 900
Query: 901 PKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRY 960
PKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRY
Sbjct: 901 PKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRY 960
Query: 961 TEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1015
TEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL
Sbjct: 961 TEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1015
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 2056 bits (5328), Expect = 0.0
Identities = 1014/1037 (97%), Positives = 1014/1037 (97%), Gaps = 22/1037 (2%)
Query: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
Sbjct: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
Query: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
Sbjct: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
Query: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
Sbjct: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
Query: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
Sbjct: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
Query: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
Sbjct: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
Query: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
Sbjct: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
Query: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
Sbjct: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
Query: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
Sbjct: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
Query: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
Sbjct: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
Query: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGR--- 597
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSG
Sbjct: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE 600
Query: 598 -------------------RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 638
RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
Sbjct: 601 CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 660
Query: 639 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 698
QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
Sbjct: 661 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 720
Query: 699 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 758
FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
Sbjct: 721 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 780
Query: 759 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 818
LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
Sbjct: 781 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 840
Query: 819 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 878
PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
Sbjct: 841 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 900
Query: 879 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 938
MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
Sbjct: 901 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 960
Query: 939 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 998
PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
Sbjct: 961 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 1020
Query: 999 NSLQEMKVQLVNGMVPL 1015
NSLQEMKVQLVNGMVPL
Sbjct: 1021 NSLQEMKVQLVNGMVPL 1037
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapiens]
Length = 983
Score = 1410 bits (3650), Expect = 0.0
Identities = 668/977 (68%), Positives = 819/977 (83%), Gaps = 8/977 (0%)
Query: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
Query: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
Query: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
Query: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
Query: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
Query: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
Query: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
Query: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
Query: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP-VFAASSDQSQIPVIAVS 578
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P F+ S + SQ+ +IA+S
Sbjct: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAIS 548
Query: 579 VTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 638
V +ILL VVI VL+ GR CGY K+K +E+++HF NGH+KLPG+RTY+DPHTYEDP
Sbjct: 549 AAVAIILLTVVIYVLI-GRFCGY-KSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPT 606
Query: 639 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 698
QAVHEFAKE++A+ I+I++V+GAGEFGEVCSGRLKLP K+E+ VAIKTLKVGYTEKQRRD
Sbjct: 607 QAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRD 666
Query: 699 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 758
FLGEASIMGQFDHPNII LEGVVTKSKPVMIVTEYMENGSLD+FL+K+D QFTVIQLVGM
Sbjct: 667 FLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGM 726
Query: 759 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 818
LRGI++GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
Sbjct: 727 LRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 786
Query: 819 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 878
PIRWT+PEAIA+RKFTSASDVWSYGIV+WEV+SYGERPYWEM+NQDVIKAV+EGYRLP P
Sbjct: 787 PIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPP 846
Query: 879 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 938
MDCPAALYQLMLDCWQK+RN+RPKF++IV++LDKLIRNP SLK + +A+ R SNLL + S
Sbjct: 847 MDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQS 906
Query: 939 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 998
+ +R+ G+WL + EIF YSS D +A+++ +D++++GVT+VG QKKI+
Sbjct: 907 NVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKII 966
Query: 999 NSLQEMKVQLVNGMVPL 1015
+S++ ++ Q NG VP+
Sbjct: 967 SSIKALETQSKNGPVPV 983
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 1327 bits (3434), Expect = 0.0
Identities = 642/990 (64%), Positives = 791/990 (79%), Gaps = 21/990 (2%)
Query: 37 RAPLWTCLLLCAALR---TLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENY 93
R P W L LR T A + EV LLDS+ +L WI+ P NGWEEI +DENY
Sbjct: 6 RYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENY 65
Query: 94 APIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNM 153
PI TYQVC+VME NQNNWL T+WIS A RIF+ELKFTLRDCNSLPG LGTCKETFN+
Sbjct: 66 TPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNL 125
Query: 154 YYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLA 213
YY+E+D GRNI+EN Y+KIDTIAADESFT+ DLG+R MKLNTEVR++GPLSKKGFYLA
Sbjct: 126 YYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLA 185
Query: 214 FQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV--TDEP 271
FQDVGACIALVSV+VYYKKC S++ +LA+FPDT+TG++ S L+EV G+CV+ + +
Sbjct: 186 FQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENA 245
Query: 272 PKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEE 331
P+MHCSAEGEWLVPIGKC+CKAGY++K TC+ C GF+K+S C +CP HS++ +E
Sbjct: 246 PRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKE 305
Query: 332 ASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSY 391
S+ C CE Y+R SDPP +ACTRPPSAP+N I N+N+T+V LEW PPAD GGR DV+Y
Sbjct: 306 GSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTY 365
Query: 392 YIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLS 451
I CK+C+ G C CG ++ Y+P+Q+GL++ V ++DLLAH NYTFE+EAVNGVSDLS
Sbjct: 366 RILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLS 425
Query: 452 PGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ 511
R + +V++TT QAAPS V+ V K ++ + S+ LSWQEP+ PNG+I EYEIKY+EKDQ
Sbjct: 426 RSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQ 485
Query: 512 -ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP--------V 562
E +Y+ +K+K T+ + LKP +VYVFQIRA TAAGYG +S R + T
Sbjct: 486 RERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEA 545
Query: 563 FAASSDQSQIPVIAVSVTVGVILLA-VVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIK 621
A SS+Q+ + +IAV G I+L +V G ++ R CGYSKA Q+ +EE ++FH K
Sbjct: 546 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEE-LYFH---FK 601
Query: 622 LPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELP 681
PG +TYIDP TYEDPN+AVH+FAKE++ASCI IERVIGAGEFGEVCSGRLKLPGKR++
Sbjct: 602 FPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVA 661
Query: 682 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 741
VAIKTLKVGYTEKQRRDFL EASIMGQFDHPN++HLEGVVT+ KPVMIV E+MENG+LD
Sbjct: 662 VAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDA 721
Query: 742 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 801
FL+K+DGQFTVIQLVGMLRGI+AGM+YL+DMGYVHRDLAARNIL+NSNLVCKVSDFGLSR
Sbjct: 722 FLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSR 781
Query: 802 VLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMT 861
V+EDDPEA YTT GGKIP+RWTAPEAI +RKFTSASDVWSYGIVMWEV+SYGERPYW+M+
Sbjct: 782 VIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMS 841
Query: 862 NQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLK 921
NQDVIKA+EEGYRLP+PMDCPA L+QLMLDCWQKER RPKF++IV +LDK+IRNP+SLK
Sbjct: 842 NQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLK 901
Query: 922 TLVNASCR-VSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980
T + R +S LL +++P + SVGEWL+AIKM RY + F GY+S+++VA++T+
Sbjct: 902 TPLGTCSRPISPLLDQNTP-DFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI 960
Query: 981 EDLRRLGVTLVGHQKKIMNSLQEMKVQLVN 1010
ED+ LG+TLVGHQKKIM+S+Q M+ Q+++
Sbjct: 961 EDVMSLGITLVGHQKKIMSSIQTMRAQMLH 990
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 1319 bits (3413), Expect = 0.0
Identities = 646/975 (66%), Positives = 774/975 (79%), Gaps = 13/975 (1%)
Query: 40 LWTCLL-LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDENYAPIH 97
L++CL +C A+ P+NEV LLDSR+V G+LGWIA P + GWEE+ +DE PI
Sbjct: 9 LFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIR 68
Query: 98 TYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFE 157
TYQVC VME +QNNWL T WI+ EGA R++IE+KFTLRDCNSLPG +GTCKETFN+YY+E
Sbjct: 69 TYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYE 128
Query: 158 SDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDV 217
SD+ R I+ENQ++KIDTIAADESFT++D+GDR+MKLNTE+RDVGPLSKKGFYLAFQDV
Sbjct: 129 SDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDV 188
Query: 218 GACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCS 277
GACIALVSVRV+YKKCP VR+LA FPDTITGAD+S L+EV GSCVN+S + PKM+C
Sbjct: 189 GACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCG 248
Query: 278 AEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCV 337
A+GEWLVPIG C+C AG+EE++G CQ C+ G++KA +C KCPPHSY+ E +TSC
Sbjct: 249 ADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCT 308
Query: 338 CEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKK 397
C++ +FR ++D +M CTRPPSAP N ISNVNETSV LEW P +TGGR+D+SY + CKK
Sbjct: 309 CDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKK 368
Query: 398 CNS-HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQ 456
C + C CG V Y P+Q+GLK T V + DLLAHTNYTFEI AVNGVS +P Q
Sbjct: 369 CGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQ 428
Query: 457 YVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSY 515
VSV VTTNQAAPS + V+ ++ + S++L+W EPDRPNG+ILEYE+KY+EKDQ E SY
Sbjct: 429 SVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSY 488
Query: 516 TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAAS-SDQSQIPV 574
I+++ +GL P + YVF +RARTAAGYG FS E T V + D + V
Sbjct: 489 RIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTV 548
Query: 575 IAVSVTVGVILLAVVIGV-LLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHT 633
+ VSV+ V+L+ ++I ++S RR YSKAKQ+ +EEK H+ GVRTY+DP T
Sbjct: 549 LLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEK------HLN-QGVRTYVDPFT 601
Query: 634 YEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTE 693
YEDPNQAV EFAKEI+ASCI IE+VIG GEFGEVCSGRLK+PGKRE+ VAIKTLK GYT+
Sbjct: 602 YEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTD 661
Query: 694 KQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI 753
KQRRDFL EASIMGQFDHPNIIHLEGVVTK KPVMI+TEYMENGSLD FL+KNDG+FTVI
Sbjct: 662 KQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI 721
Query: 754 QLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTT 813
QLVGMLRGI +GMKYLSDM YVHRDLAARNIL+NSNLVCKVSDFG+SRVLEDDPEAAYTT
Sbjct: 722 QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT 781
Query: 814 RGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGY 873
RGGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SYGERPYW+M+NQDVIKA+EEGY
Sbjct: 782 RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 841
Query: 874 RLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNL 933
RLP PMDCP AL+QLMLDCWQKER+ RPKF +IVNMLDKLIRNP+SLK S R +
Sbjct: 842 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTA 901
Query: 934 LAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGH 993
L + S A SVG+WL+AIKM RY + F GY++++AV V EDL R+G+T + H
Sbjct: 902 LLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITH 961
Query: 994 QKKIMNSLQEMKVQL 1008
Q KI++S+Q M+ Q+
Sbjct: 962 QNKILSSVQAMRTQM 976
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 1253 bits (3242), Expect = 0.0
Identities = 605/1002 (60%), Positives = 766/1002 (76%), Gaps = 54/1002 (5%)
Query: 58 SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSW 117
+N+V LLD+ TV+G+LGW +P NGW+ I E+DE+ PIHTYQVC VME NQNNWL T+W
Sbjct: 126 NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
Query: 118 ISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTI 177
IS + A +I++E+KFTLRDCNS+P LGTCKETFN++Y ESD+ +G K NQY KIDTI
Sbjct: 186 ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
Query: 178 AADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVV 237
AADESFT++DLGDR++KLNTE+R+VGP+ +KGFYLAFQD+GACIALVSVRV+YKKCP V
Sbjct: 246 AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
Query: 238 RHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEE 297
R+LA+FPDTI DSS L+EV GSCV + + PK++C A+G+WLVP+G+C+C GYEE
Sbjct: 306 RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
Query: 298 KNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRP 357
G+C CRPGF+KA C KCPPHS T+ EA++ C CEK YFR E DPP+MACTRP
Sbjct: 366 IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
Query: 358 PSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPR 417
PSAPRN + N+NET++ LEW PP+DTGGRKD++Y + CKKC CE+CGG +R++PR
Sbjct: 426 PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
Query: 418 QSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKK 477
+GL N SV+++D ++H NYTFEIEA+NGVS+LS + + ++ VTT+Q APS + V+K
Sbjct: 486 HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
Query: 478 GKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTIIKSKETTITAEGLKPASVY 536
++NSI+LSWQ P NG IL+YEIKY+EK+ E +Y+ +SK ++ GLKPA+ Y
Sbjct: 546 DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
Query: 537 VFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSVTVGVILLAVV-IGVLL 594
VF IR RTA GY +S++FEFET +++Q QI VIA + G LL ++ + L+
Sbjct: 606 VFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLI 665
Query: 595 SGRRCGYSKAKQDPEEEKM-HFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 653
+GR Y KAK EE++ H NGH++ PG++TYIDP TYEDP+ AVHEFAKEI+ S I
Sbjct: 666 TGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRI 725
Query: 654 TIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 713
IERVIGAGEFGEVCSGRLK PGKRE+PVAIKTLK G+ ++QRRDFL EASIMGQFDHPN
Sbjct: 726 RIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPN 785
Query: 714 IIHLEGVVTK------------------------------------------SKPVMIVT 731
II LEGVVTK +PVMIV
Sbjct: 786 IIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVV 845
Query: 732 EYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLV 791
EYMENGSLD+FL+K+DG FTVIQLVGMLRGI++GMKYLSDMGYVHRDLAARNIL+NSNLV
Sbjct: 846 EYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLV 905
Query: 792 CKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS 851
CKVSDFGLSRVLEDDPEAAYTT GGKIPIRWTAPEAIA+RKF+SASD WSYGIVMWEV+S
Sbjct: 906 CKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMS 965
Query: 852 YGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 911
YGERPYWEM+NQDVI ++EEGYRLP+PM CPA+L+QLML CWQKERN RPKF +IV+ LD
Sbjct: 966 YGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLD 1025
Query: 912 KLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYR---SVGEWLEAIKMGRYTEIFMENG 968
KLIRNPS+L TLV L+ SP Y +VG+WL++IKMG+Y F+ G
Sbjct: 1026 KLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG 1080
Query: 969 YSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVN 1010
+++ D +++++++D+RR+GV L+GHQ++I++S+Q +++ +++
Sbjct: 1081 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMH 1122
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
Length = 1005
Score = 1221 bits (3159), Expect = 0.0
Identities = 586/994 (58%), Positives = 746/994 (75%), Gaps = 23/994 (2%)
Query: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
LW + AA T +++ EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 12 LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
Query: 100 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
QVC VM NQNNWL TSW+ +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
Query: 160 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
G + +E+Q++KIDTIAADESFT DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
Query: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS + PKM+CSAE
Sbjct: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
Query: 280 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
GEWLVPIGKC+C AGYEE+ C C GF+K++P Q C +CPPHS++ A+ +C C+
Sbjct: 251 GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
Query: 340 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
Y+R DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y C++C
Sbjct: 311 LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
Query: 400 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
CE CG R++P+Q+ L S+++ +LLAH NY+F IEAVNGVSDLSP R+
Sbjct: 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
Query: 460 VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTII 518
VN+TTNQAAPS V +++ + + S+SL WQEP++PNGIILEYEIKY+EKD+E SY+ +
Sbjct: 431 VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTL 490
Query: 519 KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVS 578
K+ T T GLKP + YVFQ+RART+AG G FS+ E ET D I I ++
Sbjct: 491 KAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKP-RPRYDTRTIVWICLT 549
Query: 579 VTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHI-------------KLPGV 625
+ G+++L +++ + R CGYSKA QD +EEKMH+ NG KLP
Sbjct: 550 LITGLVVLLLLL--ICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEP 607
Query: 626 RTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIK 685
+ Y +PHTYE+P +A F +EIEAS I IE++IG+G+ GEVC GRL++PG+R++PVAIK
Sbjct: 608 QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIK 667
Query: 686 TLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKK 745
LK GYTE+QRRDFL EASIMGQFDHPNII LEGVVT+ + MIVTEYMENGSLDTFL+
Sbjct: 668 ALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRT 727
Query: 746 NDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLED 805
+DGQFT++QLVGMLRG+ AGM+YLSD+GYVHRDLAARN+L++SNLVCKVSDFGLSRVLED
Sbjct: 728 HDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLED 787
Query: 806 DPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDV 865
DP+AAYTT GGKIPIRWTAPEAIAFR F+SASDVWS+G+VMWEV++YGERPYW MTN+DV
Sbjct: 788 DPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDV 847
Query: 866 IKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVN 925
I +VEEGYRLP+PM CP AL+QLMLDCW K+R RP+F +IV++LD LIR+P SL+
Sbjct: 848 ISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATAT 907
Query: 926 AS-----CRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980
S V + G G +VG+WL++I+MGRY + F GYSS+ V ++
Sbjct: 908 VSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNA 967
Query: 981 EDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVP 1014
+D+R LG+TL+GHQKKI+ S+Q M+ QL + P
Sbjct: 968 QDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapiens]
Length = 987
Score = 1177 bits (3046), Expect = 0.0
Identities = 576/975 (59%), Positives = 742/975 (76%), Gaps = 13/975 (1%)
Query: 46 LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105
L AAL L + E L+DS T +LGW+ P +GWEE+ DEN I TYQVC V
Sbjct: 6 LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65
Query: 106 EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164
E +QNNWL T +I GA RI +E+KF++RDC+S+P G+CKETFN+YY+E+D +
Sbjct: 66 ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
Query: 165 ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221
N EN ++K+DTIAADESF+++DLG RVMK+NTEVR GP+S+ GFYLAFQD G C+
Sbjct: 126 TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
Query: 222 ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280
+L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+ GSC+ N D P K++C+ +G
Sbjct: 186 SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245
Query: 281 EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338
EWLVPIG+CMCKAG+E +NGT C+ C G FKA+ ++C CP +S T E +T+CVC
Sbjct: 246 EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305
Query: 339 EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398
Y+R + DP M CT PSAP+ IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 306 RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365
Query: 399 NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458
S G C CG +V+Y PRQ GL + + DLLAHT YTFEI+AVNGV+D SP + Q+
Sbjct: 366 GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425
Query: 459 SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517
SVN+TTNQAAPS V+ + + +SI+LSW +PD+PNG+IL+YE++Y+EK+ E + T
Sbjct: 426 SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485
Query: 518 IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576
IKS T+T +GLK ++YVFQ+RART AGYG +S + F+T T +S Q ++P+I
Sbjct: 486 IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545
Query: 577 VSVTVGVI-LLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYE 635
S G++ L+AVV+ ++ RR G+ +A + ++ H+ +GH+ PG++ YIDP TYE
Sbjct: 546 GSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMT-PGMKIYIDPFTYE 604
Query: 636 DPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQ 695
DPN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKLPGKRE+ VAIKTLK GYTEKQ
Sbjct: 605 DPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQ 664
Query: 696 RRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQL 755
RRDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+MENGSLD+FL++NDGQFTVIQL
Sbjct: 665 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 724
Query: 756 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR 814
VGMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDD + YT+
Sbjct: 725 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 784
Query: 815 -GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGY 873
GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SYGERPYW+MTNQDVI A+E+ Y
Sbjct: 785 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 844
Query: 874 RLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNL 933
RLP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK+IRNP+SLK + S ++
Sbjct: 845 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLP 904
Query: 934 LAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGH 993
L + + ++ +V EWLEAIKMG+Y E F G++S D V+Q+ +ED+ R+GVTL GH
Sbjct: 905 LLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGH 964
Query: 994 QKKIMNSLQEMKVQL 1008
QKKI+NS+Q M+ Q+
Sbjct: 965 QKKILNSIQVMRAQM 979
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sapiens]
Length = 986
Score = 1175 bits (3040), Expect = 0.0
Identities = 573/974 (58%), Positives = 738/974 (75%), Gaps = 12/974 (1%)
Query: 46 LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105
L AAL L + E L+DS T +LGW+ P +GWEE+ DEN I TYQVC V
Sbjct: 6 LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65
Query: 106 EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164
E +QNNWL T +I GA RI +E+KF++RDC+S+P G+CKETFN+YY+E+D +
Sbjct: 66 ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
Query: 165 ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221
N EN ++K+DTIAADESF+++DLG RVMK+NTEVR GP+S+ GFYLAFQD G C+
Sbjct: 126 TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
Query: 222 ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280
+L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+ GSC+ N D P K++C+ +G
Sbjct: 186 SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245
Query: 281 EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338
EWLVPIG+CMCKAG+E +NGT C+ C G FKA+ ++C CP +S T E +T+CVC
Sbjct: 246 EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305
Query: 339 EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398
Y+R + DP M CT PSAP+ IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 306 RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365
Query: 399 NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458
S G C CG +V+Y PRQ GL + + DLLAHT YTFEI+AVNGV+D SP + Q+
Sbjct: 366 GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425
Query: 459 SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517
SVN+TTNQAAPS V+ + + +SI+LSW +PD+PNG+IL+YE++Y+EK+ E + T
Sbjct: 426 SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485
Query: 518 IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576
IKS T+T +GLK ++YVFQ+RART AGYG +S + F+T T +S Q ++P+I
Sbjct: 486 IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545
Query: 577 VSVTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYED 636
S G++ L V+ + + R G+ +A + ++ H+ +GH+ PG++ YIDP TYED
Sbjct: 546 GSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMT-PGMKIYIDPFTYED 604
Query: 637 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 696
PN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKLPGKRE+ VAIKTLK GYTEKQR
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQR 664
Query: 697 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLV 756
RDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+MENGSLD+FL++NDGQFTVIQLV
Sbjct: 665 RDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLV 724
Query: 757 GMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR- 814
GMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDD + YT+
Sbjct: 725 GMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSAL 784
Query: 815 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 874
GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SYGERPYW+MTNQDVI A+E+ YR
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 875 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLL 934
LP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK+IRNP+SLK + S ++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPL 904
Query: 935 AEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQ 994
+ + ++ +V EWLEAIKMG+Y E F G++S D V+Q+ +ED+ R+GVTL GHQ
Sbjct: 905 LDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQ 964
Query: 995 KKIMNSLQEMKVQL 1008
KKI+NS+Q M+ Q+
Sbjct: 965 KKILNSIQVMRAQM 978
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 1139 bits (2945), Expect = 0.0
Identities = 564/972 (58%), Positives = 723/972 (74%), Gaps = 15/972 (1%)
Query: 50 LRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQ 107
L LLAS + E L+D+RT +LGW A P +GWEE+ DEN I TYQVC V E
Sbjct: 7 LLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEP 66
Query: 108 NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD----QNG 163
NQNNWLLT++I+ GA RI+ E++FT+RDC+SLP G+CKETFN+YY+E+D +
Sbjct: 67 NQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKS 126
Query: 164 RNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIAL 223
E Y+K+DTIAADESF+++D G R+MK+NTEVR GPL++ GFYLAFQD GAC++L
Sbjct: 127 AFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSL 186
Query: 224 VSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEGEW 282
+SVRV++KKCPS+V++ AVFP+T+TGA+S+ L+ G+C+ N D P K++C+ +GEW
Sbjct: 187 LSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEW 246
Query: 283 LVPIGKCMCKAGYEEKNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKD 341
+VPIG+C CK GYE +N C+ C G FKAS + C CP +S + EAS C C
Sbjct: 247 MVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTG 306
Query: 342 YFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSH 401
Y+R + DPP +ACT PS PRN IS VNETS+ LEW PP +TGGR DV+Y I CKKC +
Sbjct: 307 YYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRAD 366
Query: 402 AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVN 461
C C +V ++PRQ GL V + L AHT YTF+I+A+NGVS SP Q+VSVN
Sbjct: 367 RRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVN 426
Query: 462 VTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSYTIIKS 520
+TTNQAAPS V + + SI+LSW +P++PNGIIL+YEI+Y+EK+ E + ++ +S
Sbjct: 427 ITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARS 486
Query: 521 KETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSV 579
+ T +GL+P VYV Q+RART AGYG FS + F+T T S + Q+P+IA S
Sbjct: 487 QTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSA 546
Query: 580 TVGVILLAVVIGV-LLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 638
GV+ + ++ + ++ R+ YSK + +K+ ++ PG++ YIDP TYEDPN
Sbjct: 547 AAGVVFVVSLVAISIVCSRKRAYSK--EAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPN 604
Query: 639 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 698
+AV EFAKEI+ S + IE VIGAGEFGEV GRLKLPGKRE+ VAIKTLK GY+EKQRRD
Sbjct: 605 EAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRD 664
Query: 699 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 758
FL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+MENG+LD+FL++NDGQFTVIQLVGM
Sbjct: 665 FLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGM 724
Query: 759 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GG 816
LRGI+AGMKYL++M YVHRDLAARNIL+NSNLVCKVSDFGLSR L+DD + YT+ GG
Sbjct: 725 LRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGG 784
Query: 817 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLP 876
KIP+RWTAPEAIA+RKFTSASDVWSYGIVMWEV+S+GERPYW+M+NQDVI A+E+ YRLP
Sbjct: 785 KIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP 844
Query: 877 SPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAE 936
PMDCPAAL+QLMLDCWQK+RNSRP+F EIVN LDK+IRNP+SLKT+ + S L +
Sbjct: 845 PPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLD 904
Query: 937 HSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKK 996
S A+ +V +WL AIKM +Y + F+ G++S+ V Q+T EDL R+G+TL GHQKK
Sbjct: 905 RSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKK 964
Query: 997 IMNSLQEMKVQL 1008
I+NS+ M+VQ+
Sbjct: 965 ILNSIHSMRVQI 976
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 1097 bits (2838), Expect = 0.0
Identities = 550/988 (55%), Positives = 708/988 (71%), Gaps = 25/988 (2%)
Query: 35 PRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYA 94
P PL LLL L + E L+D++ V +L W + P++GWEE+ DE
Sbjct: 14 PGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMN 73
Query: 95 PIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMY 154
PI TYQVC V E +QNNWL T +I R+++ELKFT+RDCNS+P G+CKETFN++
Sbjct: 74 PIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLF 133
Query: 155 YFESDDQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGF 210
Y+E+D EN Y+K+DTIA DESF+ LD G ++NT+VR GPLSK GF
Sbjct: 134 YYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGF 189
Query: 211 YLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV-TD 269
YLAFQD GAC++L+SVR +YKKC S A+FP+T+TGA+ + L+ G+C+ ++V
Sbjct: 190 YLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVS 249
Query: 270 EPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSY 327
P K++C+ +GEW+VP+G C C G+E K C+ C PG +KA C CPP+S
Sbjct: 250 VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSR 309
Query: 328 THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK 387
T A++ C C +++R +SD ACT PS PR ISNVNETS+ LEW P D GGR
Sbjct: 310 TTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRD 369
Query: 388 DVSYYIACKKCNSHAGV--CEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN 445
D+ Y + CKKC+ G C C +V ++PRQ GL V + LLAHT YTFE++AVN
Sbjct: 370 DLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVN 429
Query: 446 GVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIK 505
GVS SP +Y +VN+TTNQAAPS V ++ + +S++LSW P+RPNG+IL+YE+K
Sbjct: 430 GVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMK 489
Query: 506 YFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565
YFEK + + T+ S+ ++ +GL+P + YV Q+RART AGYG +SR EFETT +
Sbjct: 490 YFEKSEGIASTVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGS 548
Query: 566 SSDQ--SQIPVIAVSVTVGVI-LLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKL 622
+ Q Q+P+I S T G++ ++AVV+ ++ R+ + + E+ + +
Sbjct: 549 GAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYI------A 602
Query: 623 PGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPV 682
PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE VIGAGEFGEVC GRLK PG+RE+ V
Sbjct: 603 PGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFV 662
Query: 683 AIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTF 742
AIKTLKVGYTE+QRRDFL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+MEN +LD+F
Sbjct: 663 AIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSF 722
Query: 743 LKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRV 802
L+ NDGQFTVIQLVGMLRGI+AGMKYLS+M YVHRDLAARNIL+NSNLVCKVSDFGLSR
Sbjct: 723 LRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRF 782
Query: 803 LEDDP-EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEM 860
LEDDP + YT+ GGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SYGERPYW+M
Sbjct: 783 LEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDM 842
Query: 861 TNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSL 920
+NQDVI AVE+ YRLP PMDCP AL+QLMLDCW ++RN RPKF +IVN LDKLIRN +SL
Sbjct: 843 SNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASL 902
Query: 921 KTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980
K + +A +S L + + + +VG+WL+AIKMGRY E F+ G++S D VAQ+T
Sbjct: 903 KVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTA 962
Query: 981 EDLRRLGVTLVGHQKKIMNSLQEMKVQL 1008
EDL R+GVTL GHQKKI++S+Q+M++Q+
Sbjct: 963 EDLLRIGVTLAGHQKKILSSIQDMRLQM 990
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 1027 bits (2656), Expect = 0.0
Identities = 525/984 (53%), Positives = 680/984 (69%), Gaps = 24/984 (2%)
Query: 38 APLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPI 96
A LW C L AA A+ EV LLD G+LGW+ P GW+ + + N PI
Sbjct: 11 ALLWGCALAAAA-----AAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPI 64
Query: 97 HTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYF 156
+ Y VC VM +Q+NWL T+W+ A RIFIELKFT+RDCNS PGG +CKETFN+YY
Sbjct: 65 YMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYA 124
Query: 157 ESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQD 216
ESD G N ++ + KIDTIA DE D R +KLN E R VGPL++KGFYLAFQD
Sbjct: 125 ESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQD 184
Query: 217 VGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTD---EPPK 273
+GAC+AL+SVRVYYKKCP +++ LA FP+TI G+D+ L V+G+CV+H+V E P+
Sbjct: 185 IGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPR 244
Query: 274 MHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEAS 333
MHC+ +GEWLVPIG+C+C+AGYE+ CQ C PGFFK C +CP H+ E +
Sbjct: 245 MHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGA 304
Query: 334 TSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYI 393
TSC CE+ +FR DP +M CTRPPSAP + V L W PP D+GGR+D+ Y +
Sbjct: 305 TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364
Query: 394 ACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPG 453
C++C +G C C VRY GL TSV + DL H NYTF +EA NGVS L
Sbjct: 365 TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423
Query: 454 ARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET 513
+R + + +V+ NQ P V +G+ + S+S+SW P + +YE+ Y +K
Sbjct: 424 SRSFRTASVSINQTEPPKVR--LEGR-STTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
Query: 514 SYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIP 573
SY + +++ ++T + L P + Y+ Q++A T G G S+ EF+T S + S
Sbjct: 481 SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTL-----SPEGSGNL 535
Query: 574 VIAVSVTVGVILLAVVIGV-LLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPH 632
+ V VGV+LL V+ GV RR +A+Q PE+ ++F +L ++TY+DPH
Sbjct: 536 AVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPED--VYFSKSE-QLKPLKTYVDPH 592
Query: 633 TYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLP-GKRELPVAIKTLKVGY 691
TYEDPNQAV +F EI SC+T ++VIGAGEFGEV G LK GK+E+PVAIKTLK GY
Sbjct: 593 TYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGY 652
Query: 692 TEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFT 751
TEKQR DFLGEA IMGQF H NII LEGV++K KP+MI+TEYMENG+LD FL++ DG+F+
Sbjct: 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFS 712
Query: 752 VIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 811
V+QLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNLVCKVSDFGLSRVLEDDPEA Y
Sbjct: 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATY 772
Query: 812 TTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEE 871
TT GGKIPIRWTAPEAI++RKFTSASDVWS+GIVMWEV++YGERPYWE++N +V+KA+ +
Sbjct: 773 TTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAIND 832
Query: 872 GYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVS 931
G+RLP+PMDCP+A+YQLM+ CWQ+ER RPKF +IV++LDKLIR P SLKTL + RVS
Sbjct: 833 GFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVS 892
Query: 932 NLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLV 991
L S +R+V EWLE+IKM +YTE FM GY++++ V Q+T +D++R+GV L
Sbjct: 893 IRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLP 952
Query: 992 GHQKKIMNSLQEMKVQLVNGMVPL 1015
GHQK+I SL +K Q+ +P+
Sbjct: 953 GHQKRIAYSLLGLKDQVNTVGIPI 976
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 934 bits (2414), Expect = 0.0
Identities = 478/1000 (47%), Positives = 665/1000 (66%), Gaps = 28/1000 (2%)
Query: 33 SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
+ P L+ C + LC AL P + EV LLDS+ +LGW A P NGWEEI V
Sbjct: 5 AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64
Query: 90 DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
DE+ PI TYQVC V+E NQ+NWL T WIS RIF+EL+FTLRDC+S+PG GTCKE
Sbjct: 65 DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124
Query: 150 TFNMYYFESDDQNGRN---IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
TFN+YY E++ GR + ++ KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184
Query: 207 KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T + S L+EV+G+CV HS
Sbjct: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244
Query: 267 VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPP 324
+ PP+MHC A+GEWLVP+G+C C AG++E+ C+ C PGF+K SP C CP
Sbjct: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPE 304
Query: 325 HSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLE--WIPPAD 382
HS E AST CVC+ Y R +DPP+ +CTRPPSAPR+ +++ + + L W+PPAD
Sbjct: 305 HSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPAD 364
Query: 383 TGGRKDVSYYIACKKCNSH--AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFE 440
+GGR DV+Y + C +C AG CE CG V +LPRQ+GL+ + ++ L YT
Sbjct: 365 SGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVR 424
Query: 441 IEAVNGVSDLSPGA-RQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEP---DRPN 496
+ A+NGVS + A Y V V+T AP +++ ++ S+SLSW+EP P
Sbjct: 425 VAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPG 484
Query: 497 GIILEYEIKYFEKDQ-ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV---FS 552
EYEI+Y+EK Q E +Y+++K+ T+T LKPA+ YVFQIRA + F+
Sbjct: 485 ANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFN 544
Query: 553 RRFEFETTPVFAASS-DQSQIPVIAVSVTVGVILLAVVIGVLLSGRR-CGYSKAKQDP-E 609
E +T A+ S DQS V+ V +++L V+ VL RR C Y K D +
Sbjct: 545 PSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHD 604
Query: 610 EEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCS 669
EE+++FH K+P RT++DP + D QAVH FAKE++A +T+ER +G G FGE+C
Sbjct: 605 EEELYFH---FKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCC 661
Query: 670 GRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMI 729
G L+LPG++EL VA+ L+ ++ QR FL EA +GQFDH +I+ LEGVVT+ +MI
Sbjct: 662 GCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMI 721
Query: 730 VTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSN 789
VTEYM +G+LD FL++++GQ QL+G+L G+++ MKYLS+MGYVHR LAAR++L++S+
Sbjct: 722 VTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSD 781
Query: 790 LVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEV 849
LVCK+S FG R D EA YTT G+ P W APE + F F+SASDVWS+GI+MWEV
Sbjct: 782 LVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEV 839
Query: 850 VSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNM 909
+++GERPYW+M+ QDVIKAVE+G+RLP P +CP L++LMLDCWQK+ RP+F +I ++
Sbjct: 840 MAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSI 899
Query: 910 LDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGY 969
L K++++P K + R LA+ + ++ SVG WLEA+ + RY + F GY
Sbjct: 900 LSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGY 959
Query: 970 SSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLV 1009
S++AVA++T +DL LG++L H++ +++ + ++ +++
Sbjct: 960 GSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVL 999
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 925 bits (2391), Expect = 0.0
Identities = 486/985 (49%), Positives = 650/985 (65%), Gaps = 31/985 (3%)
Query: 44 LLLC-AALRTLLASPSNEVNLLDSRTVMGDLGWIAFPK--NGWEEIGEVDENYAPIHTYQ 100
+LLC A+L L E LL+++ DL W+ FP+ WEE+ +DE + TY+
Sbjct: 5 VLLCWASLAAAL-----EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYE 59
Query: 101 VCKVMEQ-NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
VC V Q +WL T W+ GA ++ L+FT+ +C SLP +CKETF ++Y+ESD
Sbjct: 60 VCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESD 119
Query: 160 DQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQ 215
+ EN YIK+DT+AA+ + + K+N + +GPLSK GFYLAFQ
Sbjct: 120 ADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQ 179
Query: 216 DVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVT--DEPPK 273
D GAC+AL+S+ ++YKKC + +L FP+T+ ++ V+GSCV +V P
Sbjct: 180 DQGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPS 236
Query: 274 MHCSAEGEWLV-PIGKCMCKAGYE--EKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHE 330
++C +G+W P+ C C G+E E N C+ C G FK SC CP +S+++
Sbjct: 237 LYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNT 296
Query: 331 EASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVS 390
S C C YFR +DP CT PPSAPR+ +S +N +S+ LEW P ++GGR+D++
Sbjct: 297 IGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLT 356
Query: 391 YYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL 450
Y + C++C G C CGG + + P L V++ L YTFE+ A+NGVS L
Sbjct: 357 YALRCRECRP-GGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSL 415
Query: 451 SPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD 510
+ G + VNVTT++ P V++++ + + +S+SL+W P P+G +L+YE+KY EK
Sbjct: 416 ATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKG 475
Query: 511 QE--TSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSD 568
E +S +K+ E GLK + Y+ Q+RAR+ AGYG F + +T + +
Sbjct: 476 AEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQ-LDESEGW 534
Query: 569 QSQIPVIAVSVTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTY 628
+ Q+ +IA + VGV+L+ VVI V + R K E E H ++ G + Y
Sbjct: 535 REQLALIAGTAVVGVVLVLVVIVVAVLCLR----KQSNGREAEYSDKHGQYLIGHGTKVY 590
Query: 629 IDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLK 688
IDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGEVC GRLK PGK+E VAIKTLK
Sbjct: 591 IDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLK 650
Query: 689 VGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG 748
GYTE+QRR+FL EASIMGQF+HPNII LEGVVT S PVMI+TE+MENG+LD+FL+ NDG
Sbjct: 651 GGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDG 710
Query: 749 QFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-P 807
QFTVIQLVGMLRGI++GM+YL++M YVHRDLAARNIL+NSNLVCKVSDFGLSR LE++
Sbjct: 711 QFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSS 770
Query: 808 EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVI 866
+ YT+ GGKIPIRWTAPEAIAFRKFTSASD WSYGIVMWEV+S+GERPYW+M+NQDVI
Sbjct: 771 DPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVI 830
Query: 867 KAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNA 926
A+E+ YRLP P DCP +L+QLMLDCWQK+RN+RP+F ++V+ LDK+IRNP+SLK +
Sbjct: 831 NAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARE 890
Query: 927 SCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRL 986
+ S+ L + A+ SVGEWL AIKMGRY E F G+ S + V+Q++ EDL R+
Sbjct: 891 NGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRI 950
Query: 987 GVTLVGHQKKIMNSLQEMKVQLVNG 1011
GVTL GHQKKI+ S+Q MK Q G
Sbjct: 951 GVTLAGHQKKILASVQHMKSQAKPG 975
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 798 bits (2060), Expect = 0.0
Identities = 433/987 (43%), Positives = 610/987 (61%), Gaps = 31/987 (3%)
Query: 36 RRAPLWT--CLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDEN 92
RR PL LLLCA L + + EV L+D+ G+LGW+ P K+GW E ++ N
Sbjct: 3 RRWPLGLGLVLLLCAPLPP--GARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LN 59
Query: 93 YAPIHTYQVCKVM-EQNQNNWLLTSWI-SNEGASRIFIELKFTLRDCNSLPGGLGT--CK 148
P++ YQ C + ++ ++WL ++WI E ASR+ +EL+FT+RDC S PGG G CK
Sbjct: 60 GTPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCK 119
Query: 149 ETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKK 208
ETFN+ Y ESD G ++ + K+ T+AAD+SFT DL +KLN E +G L+++
Sbjct: 120 ETFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRR 179
Query: 209 GFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS-V 267
G YLAF + GAC+ALVSVRV+Y++CP + LA FPDT+ G + L+EV+G+C+ H+
Sbjct: 180 GLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARA 237
Query: 268 TDEP---PKMHCSAEGEWLVPIGKCMCKAGYEEKNG--TCQVCRPGFFKASPHIQSCGKC 322
+ P P+MHCS +GEWLVP+G+C C+ GYEE C C G ++ C C
Sbjct: 238 SPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTC 297
Query: 323 PPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPAD 382
P S E +T C CE ++R + P +ACT PPSAPRN + + T + L W PPAD
Sbjct: 298 PQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPAD 357
Query: 383 TGGRKDVSYYIACKKCNSHA---GVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTF 439
TGGR+DV Y + C +C A G C+ CG V + P GL +V + L + NYTF
Sbjct: 358 TGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTF 417
Query: 440 EIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQ-EPDRPNGI 498
+EA NGVS L SV+++ A +++ K + L+W R G
Sbjct: 418 NVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGA 477
Query: 499 ILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFE 558
L YE+ +D+E ++ E + L+P + Y+ ++R T G G FS EF
Sbjct: 478 NLTYELHVLNQDEERYQMVL---EPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFR 534
Query: 559 TTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNG 618
T+P + +I + + +G LL +G+L+ R + +Q + ++ +
Sbjct: 535 TSPPVSRGLTGGEIVAVIFGLLLGAALL---LGILVFRSRRA-QRQRQQRQRDRATDVDR 590
Query: 619 HIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR 678
KL ++ Y+D YEDP Q +F +E++ + + ++ VIG GEFGEV G L+LP +
Sbjct: 591 EDKL-WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQD 649
Query: 679 ELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGS 738
VAIKTLK Q +FL EA+IMGQF HP+I+HLEGVVTK KP+MI+TE+MENG+
Sbjct: 650 CKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGA 709
Query: 739 LDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFG 798
LD FL++ + Q QLV ML+GI++GM YLS+ YVHRDLAARNIL+N NL CKVSDFG
Sbjct: 710 LDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFG 769
Query: 799 LSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYW 858
L+R+L DD + Y T+GGKIPIRWTAPEAIA R FT+ASDVWS+GIVMWEV+S+G++PY
Sbjct: 770 LTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828
Query: 859 EMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPS 918
EM+NQ+V+K++E+GYRLP P+DCPA LY+LM +CW +R RP F ++ L++L+ NP
Sbjct: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888
Query: 919 SLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQV 978
SL+T+ N R++ L S YR+V EWLE+I+M RY F G +M+ V ++
Sbjct: 889 SLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLEL 948
Query: 979 TLEDLRRLGVTLVGHQKKIMNSLQEMK 1005
T EDL ++G+TL GHQK+I+ S+Q K
Sbjct: 949 TAEDLTQMGITLPGHQKRILCSIQGFK 975
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 759 bits (1960), Expect = 0.0
Identities = 407/1023 (39%), Positives = 599/1023 (58%), Gaps = 83/1023 (8%)
Query: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
LW LL+ + L E LLD+ ++GW+ +P GW+E+ +D+ T+
Sbjct: 20 LWVLLLVSSVLAL-------EEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTF 72
Query: 100 QVCKVMEQ----NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYY 155
+ C V Q+NWL T ++ GA R I L F++R C+SL GTC+ETF +YY
Sbjct: 73 EACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYY 132
Query: 156 FESDDQNGRNIKENQYIK----IDTIAADESFTELD-----------------LGDRV-M 193
++++ + + + ++K +DTIAADESF G R +
Sbjct: 133 RQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGL 192
Query: 194 KLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDT-ITGADS 252
+LN + R GPL+++GFY+AFQD GAC+ALV+VR++ CP+V+R A FP+T +GA
Sbjct: 193 QLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGG 252
Query: 253 SQLLEVSGSCVNHSVTDE----------PPKMHCSAEGEWLVPIGKCMCKAGYEEKNG-- 300
+ L+ G+CV H+ +E PP++HC+ EG+W+V +G C C+ GY+ G
Sbjct: 253 ASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDK 312
Query: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
CQ C G +K+S C CP S+ A+ C C + ++R SDPP CT PPSA
Sbjct: 313 ACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSA 372
Query: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSH-------AGVCEECGGHVR 413
P+ V +++ L W P + GGR D+ + + CK+C G C C V
Sbjct: 373 PQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVH 432
Query: 414 YLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVT 473
+ PRQ GL + V++ L AH Y E++AVNGVS+LSP Q ++NV+T+ PS V
Sbjct: 433 FDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVP 492
Query: 474 NVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKET-TITAEGLKP 532
V + A NSI++SW +PD+ NG IL+Y+++Y+++ ++ S++ + ET T T L P
Sbjct: 493 VVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSP 552
Query: 533 ASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVI---LLAV- 588
+Y FQ+RARTAAG+G + + F+T P SS + + + +G + LLA
Sbjct: 553 GHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAI 612
Query: 589 -VIGVLLSGRR--CGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFA 645
V+ V+ +R GY++ Q + GV+ YIDP TYEDP QA+ E A
Sbjct: 613 TVLAVVFQRKRRGTGYTEQLQQYSSPGL----------GVKYYIDPSTYEDPCQAIRELA 662
Query: 646 KEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASI 705
+E++ + I IE VIG G FGEV GRL+ G+RE VAI+ L G E + FLG A++
Sbjct: 663 REVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAV 722
Query: 706 MGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAG 765
+GQF HPNI+ LEGVVTKS+P+M++TE+ME G LD+FL++ +GQF+ +QLV M RG++A
Sbjct: 723 LGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAA 782
Query: 766 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAP 825
M+YLS +VHR L+A ++L+NS+LVCKV+ G ++ +G +RW AP
Sbjct: 783 MQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG------------HSPQGPSCLLRWAAP 830
Query: 826 EAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAAL 885
E IA K T++SDVWS+GI+MWEV+SYGERPYW+M+ Q+V+ A+E+ +RLP P CP L
Sbjct: 831 EVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGL 890
Query: 886 YQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAY 945
+ LMLD WQK+R RP FD++V DK+IR P +L+ + R S L L
Sbjct: 891 HLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCL 950
Query: 946 RSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMK 1005
S WL AI + Y + F + G + VAQ++LEDL LG+TL GHQKK+++ +Q ++
Sbjct: 951 DSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQ 1010
Query: 1006 VQL 1008
L
Sbjct: 1011 QHL 1013
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 737 bits (1902), Expect = 0.0
Identities = 339/522 (64%), Positives = 423/522 (81%), Gaps = 5/522 (0%)
Query: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
Query: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
Query: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
Query: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
Query: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
Query: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
Query: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
Query: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
Query: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP 561
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P
Sbjct: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 555 bits (1430), Expect = e-158
Identities = 253/428 (59%), Positives = 322/428 (75%), Gaps = 1/428 (0%)
Query: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
LW + AA T +++ EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 12 LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
Query: 100 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
QVC VM NQNNWL TSW+ +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
Query: 160 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
G + +E+Q++KIDTIAADESFT DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
Query: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS + PKM+CSAE
Sbjct: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
Query: 280 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
GEWLVPIGKC+C AGYEE+ C C GF+K++P Q C +CPPHS++ A+ +C C+
Sbjct: 251 GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
Query: 340 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
Y+R DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y C++C
Sbjct: 311 LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
Query: 400 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
CE CG R++P+Q+ L S+++ +LLAH NY+F IEAVNGVSDLSP R+
Sbjct: 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
Query: 460 VNVTTNQA 467
VN+TTNQA
Sbjct: 431 VNITTNQA 438
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 318 bits (814), Expect = 2e-86
Identities = 158/279 (56%), Positives = 200/279 (71%), Gaps = 8/279 (2%)
Query: 33 SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
+ P L+ C + LC AL P + EV LLDS+ +LGW A P NGWEEI V
Sbjct: 5 AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64
Query: 90 DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
DE+ PI TYQVC V+E NQ+NWL T WIS RIF+EL+FTLRDC+S+PG GTCKE
Sbjct: 65 DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124
Query: 150 TFNMYYFESDDQNGR---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
TFN+YY E++ GR + ++ KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184
Query: 207 KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T + S L+EV+G+CV HS
Sbjct: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244
Query: 267 VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQ 303
+ PP+MHC A+GEWLVP+G+C C AG++E+ C+
Sbjct: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283
>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
Length = 1370
Score = 236 bits (601), Expect = 1e-61
Identities = 158/513 (30%), Positives = 253/513 (49%), Gaps = 37/513 (7%)
Query: 416 PRQSGLKNTSVMMVDLLAHTNYTFEIEAVN-GVSDLSPGARQYVSVNVTTNQAAPSPVTN 474
P + + S+++ L T Y E++A N + YVS A V
Sbjct: 785 PFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGP 844
Query: 475 VKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSK----ETTITAEGL 530
V N + L WQEP PNG+I+ YE+ Y E + + K E GL
Sbjct: 845 VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGL 904
Query: 531 KPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVI 590
P + Y +IRA + AG G + T P + +D +P + +G ++ +
Sbjct: 905 SPGN-YSVRIRATSLAGNGSW-------TEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLF 956
Query: 591 GVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEA 650
V++ K + D ++ + L + P + P++ E+
Sbjct: 957 SVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVF--PCSVYVPDEW------EVSR 1008
Query: 651 SCITIERVIGAGEFGEVCSGRLK--LPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQ 708
IT+ R +G G FG V G + + G+ E VA+KT+ + ++R +FL EAS+M
Sbjct: 1009 EKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG 1068
Query: 709 FDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKK-------NDGQF--TVIQLVGML 759
F +++ L GVV+K +P ++V E M +G L ++L+ N G+ T+ +++ M
Sbjct: 1069 FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA 1128
Query: 760 RGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK-- 817
I+ GM YL+ +VHRDLAARN ++ + K+ DFG++R D E Y +GGK
Sbjct: 1129 AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYETDYYRKGGKGL 1185
Query: 818 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS 877
+P+RW APE++ FT++SD+WS+G+V+WE+ S E+PY ++N+ V+K V +G L
Sbjct: 1186 LPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQ 1245
Query: 878 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 910
P +CP + LM CWQ RP F EIVN+L
Sbjct: 1246 PDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1278
>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
Length = 1382
Score = 236 bits (601), Expect = 1e-61
Identities = 158/513 (30%), Positives = 253/513 (49%), Gaps = 37/513 (7%)
Query: 416 PRQSGLKNTSVMMVDLLAHTNYTFEIEAVN-GVSDLSPGARQYVSVNVTTNQAAPSPVTN 474
P + + S+++ L T Y E++A N + YVS A V
Sbjct: 797 PFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGP 856
Query: 475 VKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSK----ETTITAEGL 530
V N + L WQEP PNG+I+ YE+ Y E + + K E GL
Sbjct: 857 VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGL 916
Query: 531 KPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVI 590
P + Y +IRA + AG G + T P + +D +P + +G ++ +
Sbjct: 917 SPGN-YSVRIRATSLAGNGSW-------TEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLF 968
Query: 591 GVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEA 650
V++ K + D ++ + L + P + P++ E+
Sbjct: 969 SVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVF--PCSVYVPDEW------EVSR 1020
Query: 651 SCITIERVIGAGEFGEVCSGRLK--LPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQ 708
IT+ R +G G FG V G + + G+ E VA+KT+ + ++R +FL EAS+M
Sbjct: 1021 EKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG 1080
Query: 709 FDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKK-------NDGQF--TVIQLVGML 759
F +++ L GVV+K +P ++V E M +G L ++L+ N G+ T+ +++ M
Sbjct: 1081 FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA 1140
Query: 760 RGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK-- 817
I+ GM YL+ +VHRDLAARN ++ + K+ DFG++R D E Y +GGK
Sbjct: 1141 AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYETDYYRKGGKGL 1197
Query: 818 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS 877
+P+RW APE++ FT++SD+WS+G+V+WE+ S E+PY ++N+ V+K V +G L
Sbjct: 1198 LPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQ 1257
Query: 878 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 910
P +CP + LM CWQ RP F EIVN+L
Sbjct: 1258 PDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1290
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 229 bits (583), Expect = 1e-59
Identities = 120/277 (43%), Positives = 175/277 (63%), Gaps = 12/277 (4%)
Query: 637 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 696
P + + A EI + +E+ +GAG+FGEV + VA+KT+K G +
Sbjct: 246 PQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYN----KHTKVAVKTMKPGSMSVEA 301
Query: 697 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 755
FL EA++M H ++ L VVTK +P+ I+TE+M GSL FLK ++G + +L
Sbjct: 302 --FLAEANVMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKL 358
Query: 756 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 814
+ I+ GM ++ Y+HRDL A NIL++++LVCK++DFGL+RV+ED+ YT R
Sbjct: 359 IDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE---YTARE 415
Query: 815 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 874
G K PI+WTAPEAI F FT SDVWS+GI++ E+V+YG PY M+N +VI+A+E GYR
Sbjct: 416 GAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYR 475
Query: 875 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 911
+P P +CP LY +M+ CW+ RP F+ I ++LD
Sbjct: 476 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 226 bits (577), Expect = 6e-59
Identities = 121/277 (43%), Positives = 175/277 (63%), Gaps = 11/277 (3%)
Query: 637 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 696
P + + A EI I + + +GAG+FGEV G K VA+KTLK G Q
Sbjct: 210 PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA 265
Query: 697 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 755
FL EA++M H ++ L VVT+ +P+ I+TEYM GSL FLK ++G ++ +L
Sbjct: 266 --FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKL 323
Query: 756 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 814
+ I+ GM Y+ Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+ YT R
Sbjct: 324 IDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTARE 380
Query: 815 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 874
G K PI+WTAPEAI F FT SDVWS+GI+++E+V+YG+ PY TN DV+ A+ +GYR
Sbjct: 381 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYR 440
Query: 875 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 911
+P +CP LY +M CW+++ RP FD + ++LD
Sbjct: 441 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLD 477
>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform A [Homo sapiens]
Length = 512
Score = 226 bits (577), Expect = 6e-59
Identities = 121/277 (43%), Positives = 175/277 (63%), Gaps = 11/277 (3%)
Query: 637 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 696
P + + A EI I + + +GAG+FGEV G K VA+KTLK G Q
Sbjct: 231 PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA 286
Query: 697 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 755
FL EA++M H ++ L VVT+ +P+ I+TEYM GSL FLK ++G ++ +L
Sbjct: 287 --FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKL 344
Query: 756 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 814
+ I+ GM Y+ Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+ YT R
Sbjct: 345 IDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTARE 401
Query: 815 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 874
G K PI+WTAPEAI F FT SDVWS+GI+++E+V+YG+ PY TN DV+ A+ +GYR
Sbjct: 402 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYR 461
Query: 875 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 911
+P +CP LY +M CW+++ RP FD + ++LD
Sbjct: 462 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLD 498
>gi|4503787 fyn-related kinase [Homo sapiens]
Length = 505
Score = 223 bits (568), Expect = 7e-58
Identities = 116/275 (42%), Positives = 167/275 (60%), Gaps = 8/275 (2%)
Query: 647 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 706
EI+ + I + + +G+G+FGEV G PVA+KTLK G + DFL EA IM
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWN----NTTPVAVKTLKPGSMDPN--DFLREAQIM 281
Query: 707 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-QFTVIQLVGMLRGISAG 765
HP +I L V T P+ I+TE M +GSL +L+ + G + + Q V M +++G
Sbjct: 282 KNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASG 341
Query: 766 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGG-KIPIRWTA 824
M YL Y+HRDLAARN+L+ + + KV+DFGL+RV + D E Y +R K+P++WTA
Sbjct: 342 MAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTA 401
Query: 825 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 884
PEAI KF+ SDVWS+GI+++E+++YG+ PY MT VI+ + + YRLP P +CP
Sbjct: 402 PEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQ 461
Query: 885 LYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSS 919
Y +ML+CW E RP F+ + L+ SS
Sbjct: 462 FYNIMLECWNAEPKERPTFETLRWKLEDYFETDSS 496
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 223 bits (567), Expect = 9e-58
Identities = 126/281 (44%), Positives = 176/281 (62%), Gaps = 12/281 (4%)
Query: 633 TYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYT 692
T + Q + + A EI + +E +G G FGEV G K VAIKTLK G
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312
Query: 693 EKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV 752
+ FL EA IM + H ++ L VV++ +P+ IVTE+M GSL FLK+ DG++
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLK 369
Query: 753 I-QLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 811
+ QLV M I+ GM Y+ M Y+HRDL A NIL+ NLVCK++DFGL+R++ED+ Y
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---Y 426
Query: 812 TTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 870
T R G K PI+WTAPEA + +FT SDVWS+GI+ E+V+ G PY M N++V++ VE
Sbjct: 427 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE 486
Query: 871 EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 911
GYR+P P CP +L++LM CW+K+ + RP F+ I + L+
Sbjct: 487 RGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 222 bits (566), Expect = 1e-57
Identities = 116/268 (43%), Positives = 161/268 (60%), Gaps = 3/268 (1%)
Query: 647 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 706
EI+ I + R IG G+FG+V G P L VAIKT K ++ R FL EA M
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497
Query: 707 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGM 766
QFDHP+I+ L GV+T++ PV I+ E G L +FL+ + L+ +S +
Sbjct: 498 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556
Query: 767 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPE 826
YL +VHRD+AARN+L++SN K+ DFGLSR +ED Y GK+PI+W APE
Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPE 614
Query: 827 AIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALY 886
+I FR+FTSASDVW +G+ MWE++ +G +P+ + N DVI +E G RLP P +CP LY
Sbjct: 615 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLY 674
Query: 887 QLMLDCWQKERNSRPKFDEIVNMLDKLI 914
LM CW + + RP+F E+ L ++
Sbjct: 675 SLMTKCWAYDPSRRPRFTELKAQLSTIL 702
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 222 bits (566), Expect = 1e-57
Identities = 116/268 (43%), Positives = 161/268 (60%), Gaps = 3/268 (1%)
Query: 647 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 706
EI+ I + R IG G+FG+V G P L VAIKT K ++ R FL EA M
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475
Query: 707 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGM 766
QFDHP+I+ L GV+T++ PV I+ E G L +FL+ + L+ +S +
Sbjct: 476 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
Query: 767 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPE 826
YL +VHRD+AARN+L++SN K+ DFGLSR +ED Y GK+PI+W APE
Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPE 592
Query: 827 AIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALY 886
+I FR+FTSASDVW +G+ MWE++ +G +P+ + N DVI +E G RLP P +CP LY
Sbjct: 593 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLY 652
Query: 887 QLMLDCWQKERNSRPKFDEIVNMLDKLI 914
LM CW + + RP+F E+ L ++
Sbjct: 653 SLMTKCWAYDPSRRPRFTELKAQLSTIL 680
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 222 bits (565), Expect = 2e-57
Identities = 118/267 (44%), Positives = 171/267 (64%), Gaps = 12/267 (4%)
Query: 647 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 706
EI + + + +G G+FGEV G K VAIKTLK G + FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318
Query: 707 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QLVGMLRGISAG 765
+ H ++ L VV++ +P+ IVTEYM GSL FLK +G+ + LV M ++AG
Sbjct: 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query: 766 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR-GGKIPIRWTA 824
M Y+ M Y+HRDL + NIL+ + L+CK++DFGL+R++ED+ YT R G K PI+WTA
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTA 434
Query: 825 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 884
PEA + +FT SDVWS+GI++ E+V+ G PY M N++V++ VE GYR+P P DCP +
Sbjct: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 494
Query: 885 LYQLMLDCWQKERNSRPKFDEIVNMLD 911
L++LM+ CW+K+ RP F+ + + L+
Sbjct: 495 LHELMIHCWKKDPEERPTFEYLQSFLE 521
>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 221 bits (562), Expect = 4e-57
Identities = 122/283 (43%), Positives = 175/283 (61%), Gaps = 12/283 (4%)
Query: 631 PHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVG 690
P + P + E E+ + + +GAG+FGEV G K VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278
Query: 691 YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-Q 749
FL EA++M Q H ++ L VVT+ +P+ I+TEYMENGSL FLK G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIK 335
Query: 750 FTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEA 809
T+ +L+ M I+ GM ++ + Y+HRDL A NIL++ L CK++DFGL+R++ED+
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393
Query: 810 AYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKA 868
YT R G K PI+WTAPEAI + FT SDVWS+GI++ E+V++G PY MTN +VI+
Sbjct: 394 -YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN 452
Query: 869 VEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 911
+E GYR+ P +CP LYQLM CW++ RP FD + ++L+
Sbjct: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,403,713
Number of Sequences: 37866
Number of extensions: 1982007
Number of successful extensions: 9335
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 607
Number of HSP's successfully gapped in prelim test: 356
Number of HSP's that attempted gapping in prelim test: 5504
Number of HSP's gapped (non-prelim): 2167
length of query: 1015
length of database: 18,247,518
effective HSP length: 112
effective length of query: 903
effective length of database: 14,006,526
effective search space: 12647892978
effective search space used: 12647892978
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.