Guide to the Human Genome
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Search of human proteins with 221625401

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
         (1037 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...  2122   0.0  
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...  2056   0.0  
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi...  1398   0.0  
gi|4758282 ephrin receptor EphA7 [Homo sapiens]                      1313   0.0  
gi|4758280 ephrin receptor EphA4 [Homo sapiens]                      1305   0.0  
gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                1243   0.0  
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...  1212   0.0  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...  1165   0.0  
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...  1164   0.0  
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]            1130   0.0  
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]           1088   0.0  
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                     1015   0.0  
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]                 926   0.0  
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                  917   0.0  
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                     789   0.0  
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]           756   0.0  
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi...   737   0.0  
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi...   555   e-158
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]                318   2e-86
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]     229   1e-59
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...   226   7e-59
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...   226   7e-59
gi|4503787 fyn-related kinase [Homo sapiens]                          223   7e-58
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]              223   1e-57
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]   222   1e-57
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]   222   1e-57
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]       222   2e-57
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs...   221   4e-57
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs...   221   4e-57
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...   220   5e-57

>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 2122 bits (5499), Expect = 0.0
 Identities = 1037/1037 (100%), Positives = 1037/1037 (100%)

Query: 1    MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
            MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
Sbjct: 1    MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60

Query: 61   VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
            VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
Sbjct: 61   VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120

Query: 121  EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
            EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
Sbjct: 121  EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180

Query: 181  ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
            ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
Sbjct: 181  ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240

Query: 241  AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
            AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
Sbjct: 241  AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300

Query: 301  TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
            TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
Sbjct: 301  TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360

Query: 361  PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
            PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
Sbjct: 361  PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420

Query: 421  LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
            LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
Sbjct: 421  LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480

Query: 481  AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
            AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
Sbjct: 481  AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540

Query: 541  RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE 600
            RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE
Sbjct: 541  RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE 600

Query: 601  CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 660
            CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
Sbjct: 601  CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 660

Query: 661  QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 720
            QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
Sbjct: 661  QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 720

Query: 721  FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 780
            FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
Sbjct: 721  FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 780

Query: 781  LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 840
            LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
Sbjct: 781  LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 840

Query: 841  PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 900
            PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
Sbjct: 841  PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 900

Query: 901  MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 960
            MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
Sbjct: 901  MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 960

Query: 961  PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 1020
            PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
Sbjct: 961  PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 1020

Query: 1021 NSLQEMKVQLVNGMVPL 1037
            NSLQEMKVQLVNGMVPL
Sbjct: 1021 NSLQEMKVQLVNGMVPL 1037


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 2056 bits (5328), Expect = 0.0
 Identities = 1014/1037 (97%), Positives = 1014/1037 (97%), Gaps = 22/1037 (2%)

Query: 1    MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
            MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
Sbjct: 1    MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60

Query: 61   VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
            VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
Sbjct: 61   VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120

Query: 121  EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
            EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
Sbjct: 121  EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180

Query: 181  ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
            ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
Sbjct: 181  ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240

Query: 241  AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
            AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
Sbjct: 241  AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300

Query: 301  TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
            TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
Sbjct: 301  TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360

Query: 361  PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
            PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
Sbjct: 361  PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420

Query: 421  LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
            LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
Sbjct: 421  LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480

Query: 481  AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
            AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
Sbjct: 481  AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540

Query: 541  RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE 600
            RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSG    
Sbjct: 541  RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGR--- 597

Query: 601  CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 660
                               RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
Sbjct: 598  -------------------RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 638

Query: 661  QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 720
            QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
Sbjct: 639  QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 698

Query: 721  FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 780
            FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
Sbjct: 699  FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 758

Query: 781  LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 840
            LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
Sbjct: 759  LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 818

Query: 841  PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 900
            PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
Sbjct: 819  PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 878

Query: 901  MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 960
            MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
Sbjct: 879  MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 938

Query: 961  PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 1020
            PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
Sbjct: 939  PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 998

Query: 1021 NSLQEMKVQLVNGMVPL 1037
            NSLQEMKVQLVNGMVPL
Sbjct: 999  NSLQEMKVQLVNGMVPL 1015


>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapiens]
          Length = 983

 Score = 1398 bits (3618), Expect = 0.0
 Identities = 668/999 (66%), Positives = 819/999 (81%), Gaps = 30/999 (3%)

Query: 44   LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
            LL C+ L +   L+  PSNEVNLLDS+T+ G+LGWI++P +GWEEI  VDE+Y PI TYQ
Sbjct: 10   LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69

Query: 101  VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
            VC VM+ +QNNWL T+W+    A +I++ELKFTLRDCNS+P  LGTCKETFN+YY ESDD
Sbjct: 70   VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129

Query: 161  QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
             +G   +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 130  DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189

Query: 221  IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
            +ALVSVRVY+KKCP  V++LA+FPDT+   DS  L+EV GSCVN+S  ++PP+M+CS EG
Sbjct: 190  VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248

Query: 281  EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
            EWLVPIGKC C AGYEE+   CQ CRPGF+KA      C KCPPHS T E+ S +C CE 
Sbjct: 249  EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308

Query: 341  DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
            +YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W  P DTGGRKDV++ I CKKC  
Sbjct: 309  NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368

Query: 401  HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
            +   CE C  +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS   RQ+ +V
Sbjct: 369  NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428

Query: 461  NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
            ++TTNQAAPSPV  +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 429  SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488

Query: 520  SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP-VFAASSDQSQIPVIAVS 578
            ++ T +T   LKP ++YVFQIRARTAAGYG  SR+FEFET+P  F+ S + SQ+ +IA+S
Sbjct: 489  ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAIS 548

Query: 579  VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH 638
              V +ILL VVI VL+         GR               CGY K+K   +E+++HF 
Sbjct: 549  AAVAIILLTVVIYVLI---------GRF--------------CGY-KSKHGADEKRLHFG 584

Query: 639  NGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG 698
            NGH+KLPG+RTY+DPHTYEDP QAVHEFAKE++A+ I+I++V+GAGEFGEVCSGRLKLP 
Sbjct: 585  NGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPS 644

Query: 699  KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMEN 758
            K+E+ VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNII LEGVVTKSKPVMIVTEYMEN
Sbjct: 645  KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMEN 704

Query: 759  GSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSD 818
            GSLD+FL+K+D QFTVIQLVGMLRGI++GMKYLSDMGYVHRDLAARNILINSNLVCKVSD
Sbjct: 705  GSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSD 764

Query: 819  FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP 878
            FGLSRVLEDDPEAAYTTRGGKIPIRWT+PEAIA+RKFTSASDVWSYGIV+WEV+SYGERP
Sbjct: 765  FGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERP 824

Query: 879  YWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRN 938
            YWEM+NQDVIKAV+EGYRLP PMDCPAALYQLMLDCWQK+RN+RPKF++IV++LDKLIRN
Sbjct: 825  YWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRN 884

Query: 939  PSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVA 998
            P SLK + +A+ R SNLL + S +    +R+ G+WL  +      EIF    YSS D +A
Sbjct: 885  PGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIA 944

Query: 999  QVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1037
            +++ +D++++GVT+VG QKKI++S++ ++ Q  NG VP+
Sbjct: 945  KISTDDMKKVGVTVVGPQKKIISSIKALETQSKNGPVPV 983


>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
          Length = 998

 Score = 1313 bits (3397), Expect = 0.0
 Identities = 643/1012 (63%), Positives = 792/1012 (78%), Gaps = 43/1012 (4%)

Query: 37   RAPLWTCLLLCAALR---TLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENY 93
            R P W  L     LR   T  A  + EV LLDS+    +L WI+ P NGWEEI  +DENY
Sbjct: 6    RYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENY 65

Query: 94   APIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNM 153
             PI TYQVC+VME NQNNWL T+WIS   A RIF+ELKFTLRDCNSLPG LGTCKETFN+
Sbjct: 66   TPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNL 125

Query: 154  YYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLA 213
            YY+E+D   GRNI+EN Y+KIDTIAADESFT+ DLG+R MKLNTEVR++GPLSKKGFYLA
Sbjct: 126  YYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLA 185

Query: 214  FQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV--TDEP 271
            FQDVGACIALVSV+VYYKKC S++ +LA+FPDT+TG++ S L+EV G+CV+ +    +  
Sbjct: 186  FQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENA 245

Query: 272  PKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEE 331
            P+MHCSAEGEWLVPIGKC+CKAGY++K  TC+ C  GF+K+S     C +CP HS++ +E
Sbjct: 246  PRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKE 305

Query: 332  ASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSY 391
             S+ C CE  Y+R  SDPP +ACTRPPSAP+N I N+N+T+V LEW PPAD GGR DV+Y
Sbjct: 306  GSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTY 365

Query: 392  YIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLS 451
             I CK+C+   G C  CG ++ Y+P+Q+GL++  V ++DLLAH NYTFE+EAVNGVSDLS
Sbjct: 366  RILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLS 425

Query: 452  PGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ 511
               R + +V++TT QAAPS V+ V K ++ + S+ LSWQEP+ PNG+I EYEIKY+EKDQ
Sbjct: 426  RSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQ 485

Query: 512  -ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP--------V 562
             E +Y+ +K+K T+ +   LKP +VYVFQIRA TAAGYG +S R +  T           
Sbjct: 486  RERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEA 545

Query: 563  FAASSDQSQIPVIAVSVTVGVILLA-VVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRC 621
             A SS+Q+ + +IAV    G I+L  +V G ++         GR               C
Sbjct: 546  TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFII---------GRR-------------HC 583

Query: 622  GYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVI 681
            GYSKA Q+ +EE ++FH    K PG +TYIDP TYEDPN+AVH+FAKE++ASCI IERVI
Sbjct: 584  GYSKADQEGDEE-LYFH---FKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVI 639

Query: 682  GAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEG 741
            GAGEFGEVCSGRLKLPGKR++ VAIKTLKVGYTEKQRRDFL EASIMGQFDHPN++HLEG
Sbjct: 640  GAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEG 699

Query: 742  VVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDL 801
            VVT+ KPVMIV E+MENG+LD FL+K+DGQFTVIQLVGMLRGI+AGM+YL+DMGYVHRDL
Sbjct: 700  VVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDL 759

Query: 802  AARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDV 861
            AARNIL+NSNLVCKVSDFGLSRV+EDDPEA YTT GGKIP+RWTAPEAI +RKFTSASDV
Sbjct: 760  AARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDV 819

Query: 862  WSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNS 921
            WSYGIVMWEV+SYGERPYW+M+NQDVIKA+EEGYRLP+PMDCPA L+QLMLDCWQKER  
Sbjct: 820  WSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAE 879

Query: 922  RPKFDEIVNMLDKLIRNPSSLKTLVNASCR-VSNLLAEHSPLGSGAYRSVGEWLEAIKMG 980
            RPKF++IV +LDK+IRNP+SLKT +    R +S LL +++P     + SVGEWL+AIKM 
Sbjct: 880  RPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTP-DFTTFCSVGEWLQAIKME 938

Query: 981  RYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVN 1032
            RY + F   GY+S+++VA++T+ED+  LG+TLVGHQKKIM+S+Q M+ Q+++
Sbjct: 939  RYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLH 990


>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
          Length = 986

 Score = 1305 bits (3378), Expect = 0.0
 Identities = 644/996 (64%), Positives = 771/996 (77%), Gaps = 33/996 (3%)

Query: 40   LWTCLL-LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDENYAPIH 97
            L++CL  +C A+      P+NEV LLDSR+V G+LGWIA P + GWEE+  +DE   PI 
Sbjct: 9    LFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIR 68

Query: 98   TYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFE 157
            TYQVC VME +QNNWL T WI+ EGA R++IE+KFTLRDCNSLPG +GTCKETFN+YY+E
Sbjct: 69   TYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYE 128

Query: 158  SDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDV 217
            SD+   R I+ENQ++KIDTIAADESFT++D+GDR+MKLNTE+RDVGPLSKKGFYLAFQDV
Sbjct: 129  SDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDV 188

Query: 218  GACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCS 277
            GACIALVSVRV+YKKCP  VR+LA FPDTITGAD+S L+EV GSCVN+S   + PKM+C 
Sbjct: 189  GACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCG 248

Query: 278  AEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCV 337
            A+GEWLVPIG C+C AG+EE++G CQ C+ G++KA     +C KCPPHSY+  E +TSC 
Sbjct: 249  ADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCT 308

Query: 338  CEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKK 397
            C++ +FR ++D  +M CTRPPSAP N ISNVNETSV LEW  P +TGGR+D+SY + CKK
Sbjct: 309  CDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKK 368

Query: 398  CNS-HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQ 456
            C +     C  CG  V Y P+Q+GLK T V + DLLAHTNYTFEI AVNGVS  +P   Q
Sbjct: 369  CGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQ 428

Query: 457  YVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSY 515
             VSV VTTNQAAPS +  V+  ++ + S++L+W EPDRPNG+ILEYE+KY+EKDQ E SY
Sbjct: 429  SVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSY 488

Query: 516  TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAAS-SDQSQIPV 574
             I+++       +GL P + YVF +RARTAAGYG FS   E  T  V +    D +   V
Sbjct: 489  RIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTV 548

Query: 575  IAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEK 634
            + VSV+  V+L+ ++I   +                         R  YSKAKQ+ +EEK
Sbjct: 549  LLVSVSGSVVLVVILIAAFVISRR---------------------RSKYSKAKQEADEEK 587

Query: 635  MHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRL 694
                  H+   GVRTY+DP TYEDPNQAV EFAKEI+ASCI IE+VIG GEFGEVCSGRL
Sbjct: 588  ------HLN-QGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRL 640

Query: 695  KLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTE 754
            K+PGKRE+ VAIKTLK GYT+KQRRDFL EASIMGQFDHPNIIHLEGVVTK KPVMI+TE
Sbjct: 641  KVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITE 700

Query: 755  YMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVC 814
            YMENGSLD FL+KNDG+FTVIQLVGMLRGI +GMKYLSDM YVHRDLAARNIL+NSNLVC
Sbjct: 701  YMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVC 760

Query: 815  KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874
            KVSDFG+SRVLEDDPEAAYTTRGGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SY
Sbjct: 761  KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 820

Query: 875  GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934
            GERPYW+M+NQDVIKA+EEGYRLP PMDCP AL+QLMLDCWQKER+ RPKF +IVNMLDK
Sbjct: 821  GERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDK 880

Query: 935  LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994
            LIRNP+SLK     S R +  L + S     A  SVG+WL+AIKM RY + F   GY+++
Sbjct: 881  LIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTL 940

Query: 995  DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
            +AV  V  EDL R+G+T + HQ KI++S+Q M+ Q+
Sbjct: 941  EAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQM 976


>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 1243 bits (3217), Expect = 0.0
 Identities = 606/1024 (59%), Positives = 767/1024 (74%), Gaps = 76/1024 (7%)

Query: 58   SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSW 117
            +N+V LLD+ TV+G+LGW  +P NGW+ I E+DE+  PIHTYQVC VME NQNNWL T+W
Sbjct: 126  NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185

Query: 118  ISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTI 177
            IS + A +I++E+KFTLRDCNS+P  LGTCKETFN++Y ESD+ +G   K NQY KIDTI
Sbjct: 186  ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245

Query: 178  AADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVV 237
            AADESFT++DLGDR++KLNTE+R+VGP+ +KGFYLAFQD+GACIALVSVRV+YKKCP  V
Sbjct: 246  AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305

Query: 238  RHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEE 297
            R+LA+FPDTI   DSS L+EV GSCV  +   + PK++C A+G+WLVP+G+C+C  GYEE
Sbjct: 306  RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365

Query: 298  KNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRP 357
              G+C  CRPGF+KA      C KCPPHS T+ EA++ C CEK YFR E DPP+MACTRP
Sbjct: 366  IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425

Query: 358  PSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPR 417
            PSAPRN + N+NET++ LEW PP+DTGGRKD++Y + CKKC      CE+CGG +R++PR
Sbjct: 426  PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485

Query: 418  QSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKK 477
             +GL N SV+++D ++H NYTFEIEA+NGVS+LS   + + ++ VTT+Q APS +  V+K
Sbjct: 486  HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545

Query: 478  GKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTIIKSKETTITAEGLKPASVY 536
               ++NSI+LSWQ P   NG IL+YEIKY+EK+ E  +Y+  +SK  ++   GLKPA+ Y
Sbjct: 546  DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605

Query: 537  VFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSVTVGVILLAVV-IGVLL 594
            VF IR RTA GY  +S++FEFET       +++Q QI VIA +   G  LL ++ +  L+
Sbjct: 606  VFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLI 665

Query: 595  SGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKM-HFHNGHIKLPGVRTYIDP 653
            +G C                    W   Y KAK   EE++  H  NGH++ PG++TYIDP
Sbjct: 666  TGRC-------------------QW---YIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDP 703

Query: 654  HTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGY 713
             TYEDP+ AVHEFAKEI+ S I IERVIGAGEFGEVCSGRLK PGKRE+PVAIKTLK G+
Sbjct: 704  DTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGH 763

Query: 714  TEKQRRDFLGEASIMGQFDHPNIIHLEGVVTK---------------------------- 745
             ++QRRDFL EASIMGQFDHPNII LEGVVTK                            
Sbjct: 764  MDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPH 823

Query: 746  --------------SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYL 791
                           +PVMIV EYMENGSLD+FL+K+DG FTVIQLVGMLRGI++GMKYL
Sbjct: 824  PVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYL 883

Query: 792  SDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA 851
            SDMGYVHRDLAARNIL+NSNLVCKVSDFGLSRVLEDDPEAAYTT GGKIPIRWTAPEAIA
Sbjct: 884  SDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIA 943

Query: 852  FRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLM 911
            +RKF+SASD WSYGIVMWEV+SYGERPYWEM+NQDVI ++EEGYRLP+PM CPA+L+QLM
Sbjct: 944  YRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLM 1003

Query: 912  LDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYR--- 968
            L CWQKERN RPKF +IV+ LDKLIRNPS+L TLV        L+   SP     Y    
Sbjct: 1004 LHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFV 1058

Query: 969  SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKV 1028
            +VG+WL++IKMG+Y   F+  G+++ D +++++++D+RR+GV L+GHQ++I++S+Q +++
Sbjct: 1059 TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRL 1118

Query: 1029 QLVN 1032
             +++
Sbjct: 1119 HMMH 1122


>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
          Length = 1005

 Score = 1212 bits (3137), Expect = 0.0
 Identities = 587/1016 (57%), Positives = 747/1016 (73%), Gaps = 45/1016 (4%)

Query: 40   LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
            LW  +   AA  T +++   EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 12   LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70

Query: 100  QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
            QVC VM  NQNNWL TSW+  +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 71   QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130

Query: 160  DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
               G + +E+Q++KIDTIAADESFT  DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 131  RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190

Query: 220  CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
            C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS   + PKM+CSAE
Sbjct: 191  CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250

Query: 280  GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
            GEWLVPIGKC+C AGYEE+   C  C  GF+K++P  Q C +CPPHS++   A+ +C C+
Sbjct: 251  GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310

Query: 340  KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
              Y+R   DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y   C++C 
Sbjct: 311  LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370

Query: 400  SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
                 CE CG   R++P+Q+ L   S+++ +LLAH NY+F IEAVNGVSDLSP  R+   
Sbjct: 371  WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430

Query: 460  VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTII 518
            VN+TTNQAAPS V  +++ +  + S+SL WQEP++PNGIILEYEIKY+EKD+E  SY+ +
Sbjct: 431  VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTL 490

Query: 519  KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVS 578
            K+  T  T  GLKP + YVFQ+RART+AG G FS+  E ET        D   I  I ++
Sbjct: 491  KAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKP-RPRYDTRTIVWICLT 549

Query: 579  VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH 638
            +  G+++L +++                  +C   H      CGYSKA QD +EEKMH+ 
Sbjct: 550  LITGLVVLLLLL------------------ICKKRH------CGYSKAFQDSDEEKMHYQ 585

Query: 639  NGHI-------------KLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGE 685
            NG               KLP  + Y +PHTYE+P +A   F +EIEAS I IE++IG+G+
Sbjct: 586  NGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGD 645

Query: 686  FGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTK 745
             GEVC GRL++PG+R++PVAIK LK GYTE+QRRDFL EASIMGQFDHPNII LEGVVT+
Sbjct: 646  SGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTR 705

Query: 746  SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARN 805
             +  MIVTEYMENGSLDTFL+ +DGQFT++QLVGMLRG+ AGM+YLSD+GYVHRDLAARN
Sbjct: 706  GRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARN 765

Query: 806  ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYG 865
            +L++SNLVCKVSDFGLSRVLEDDP+AAYTT GGKIPIRWTAPEAIAFR F+SASDVWS+G
Sbjct: 766  VLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFG 825

Query: 866  IVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKF 925
            +VMWEV++YGERPYW MTN+DVI +VEEGYRLP+PM CP AL+QLMLDCW K+R  RP+F
Sbjct: 826  VVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRF 885

Query: 926  DEIVNMLDKLIRNPSSLKTLVNAS-----CRVSNLLAEHSPLGSGAYRSVGEWLEAIKMG 980
             +IV++LD LIR+P SL+     S       V +        G G   +VG+WL++I+MG
Sbjct: 886  SQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMG 945

Query: 981  RYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVP 1036
            RY + F   GYSS+  V ++  +D+R LG+TL+GHQKKI+ S+Q M+ QL +   P
Sbjct: 946  RYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapiens]
          Length = 987

 Score = 1165 bits (3014), Expect = 0.0
 Identities = 575/996 (57%), Positives = 740/996 (74%), Gaps = 33/996 (3%)

Query: 46   LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105
            L AAL  L    + E  L+DS T   +LGW+  P +GWEE+   DEN   I TYQVC V 
Sbjct: 6    LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65

Query: 106  EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164
            E +QNNWL T +I   GA RI +E+KF++RDC+S+P   G+CKETFN+YY+E+D  +   
Sbjct: 66   ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125

Query: 165  ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221
               N  EN ++K+DTIAADESF+++DLG RVMK+NTEVR  GP+S+ GFYLAFQD G C+
Sbjct: 126  TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185

Query: 222  ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280
            +L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+   GSC+ N    D P K++C+ +G
Sbjct: 186  SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245

Query: 281  EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338
            EWLVPIG+CMCKAG+E  +NGT C+ C  G FKA+   ++C  CP +S T  E +T+CVC
Sbjct: 246  EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305

Query: 339  EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398
               Y+R + DP  M CT  PSAP+  IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 306  RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365

Query: 399  NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458
             S  G C  CG +V+Y PRQ GL    + + DLLAHT YTFEI+AVNGV+D SP + Q+ 
Sbjct: 366  GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425

Query: 459  SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517
            SVN+TTNQAAPS V+ + +     +SI+LSW +PD+PNG+IL+YE++Y+EK+  E + T 
Sbjct: 426  SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485

Query: 518  IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576
            IKS   T+T +GLK  ++YVFQ+RART AGYG +S +  F+T T     +S Q ++P+I 
Sbjct: 486  IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545

Query: 577  VSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMH 636
             S   G++ L  V+ + +        C R              R G+ +A  +  ++  H
Sbjct: 546  GSSAAGLVFLIAVVVIAIV-------CNR--------------RRGFERADSEYTDKLQH 584

Query: 637  FHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKL 696
            + +GH+  PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKL
Sbjct: 585  YTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKL 643

Query: 697  PGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYM 756
            PGKRE+ VAIKTLK GYTEKQRRDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+M
Sbjct: 644  PGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFM 703

Query: 757  ENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKV 816
            ENGSLD+FL++NDGQFTVIQLVGMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKV
Sbjct: 704  ENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKV 763

Query: 817  SDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874
            SDFGLSR LEDD  +  YT+  GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SY
Sbjct: 764  SDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 823

Query: 875  GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934
            GERPYW+MTNQDVI A+E+ YRLP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK
Sbjct: 824  GERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDK 883

Query: 935  LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994
            +IRNP+SLK +   S  ++  L + +     ++ +V EWLEAIKMG+Y E F   G++S 
Sbjct: 884  MIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSF 943

Query: 995  DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
            D V+Q+ +ED+ R+GVTL GHQKKI+NS+Q M+ Q+
Sbjct: 944  DVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQM 979


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sapiens]
          Length = 986

 Score = 1164 bits (3010), Expect = 0.0
 Identities = 574/996 (57%), Positives = 739/996 (74%), Gaps = 34/996 (3%)

Query: 46   LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105
            L AAL  L    + E  L+DS T   +LGW+  P +GWEE+   DEN   I TYQVC V 
Sbjct: 6    LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65

Query: 106  EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164
            E +QNNWL T +I   GA RI +E+KF++RDC+S+P   G+CKETFN+YY+E+D  +   
Sbjct: 66   ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125

Query: 165  ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221
               N  EN ++K+DTIAADESF+++DLG RVMK+NTEVR  GP+S+ GFYLAFQD G C+
Sbjct: 126  TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185

Query: 222  ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280
            +L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+   GSC+ N    D P K++C+ +G
Sbjct: 186  SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245

Query: 281  EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338
            EWLVPIG+CMCKAG+E  +NGT C+ C  G FKA+   ++C  CP +S T  E +T+CVC
Sbjct: 246  EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305

Query: 339  EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398
               Y+R + DP  M CT  PSAP+  IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 306  RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365

Query: 399  NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458
             S  G C  CG +V+Y PRQ GL    + + DLLAHT YTFEI+AVNGV+D SP + Q+ 
Sbjct: 366  GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425

Query: 459  SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517
            SVN+TTNQAAPS V+ + +     +SI+LSW +PD+PNG+IL+YE++Y+EK+  E + T 
Sbjct: 426  SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485

Query: 518  IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576
            IKS   T+T +GLK  ++YVFQ+RART AGYG +S +  F+T T     +S Q ++P+I 
Sbjct: 486  IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545

Query: 577  VSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMH 636
             S   G++ L  V+ + +        C R                G+ +A  +  ++  H
Sbjct: 546  GSSAAGLVFLIAVVVIAIV-------CNRR---------------GFERADSEYTDKLQH 583

Query: 637  FHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKL 696
            + +GH+  PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKL
Sbjct: 584  YTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKL 642

Query: 697  PGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYM 756
            PGKRE+ VAIKTLK GYTEKQRRDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+M
Sbjct: 643  PGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFM 702

Query: 757  ENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKV 816
            ENGSLD+FL++NDGQFTVIQLVGMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKV
Sbjct: 703  ENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKV 762

Query: 817  SDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874
            SDFGLSR LEDD  +  YT+  GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SY
Sbjct: 763  SDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 822

Query: 875  GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934
            GERPYW+MTNQDVI A+E+ YRLP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK
Sbjct: 823  GERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDK 882

Query: 935  LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994
            +IRNP+SLK +   S  ++  L + +     ++ +V EWLEAIKMG+Y E F   G++S 
Sbjct: 883  MIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSF 942

Query: 995  DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
            D V+Q+ +ED+ R+GVTL GHQKKI+NS+Q M+ Q+
Sbjct: 943  DVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQM 978


>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
          Length = 984

 Score = 1130 bits (2924), Expect = 0.0
 Identities = 570/993 (57%), Positives = 723/993 (72%), Gaps = 35/993 (3%)

Query: 50   LRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQ 107
            L  LLAS   + E  L+D+RT   +LGW A P +GWEE+   DEN   I TYQVC V E 
Sbjct: 7    LLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEP 66

Query: 108  NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD----QNG 163
            NQNNWLLT++I+  GA RI+ E++FT+RDC+SLP   G+CKETFN+YY+E+D     +  
Sbjct: 67   NQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKS 126

Query: 164  RNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIAL 223
                E  Y+K+DTIAADESF+++D G R+MK+NTEVR  GPL++ GFYLAFQD GAC++L
Sbjct: 127  AFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSL 186

Query: 224  VSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEGEW 282
            +SVRV++KKCPS+V++ AVFP+T+TGA+S+ L+   G+C+ N    D P K++C+ +GEW
Sbjct: 187  LSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEW 246

Query: 283  LVPIGKCMCKAGYEEKNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKD 341
            +VPIG+C CK GYE +N   C+ C  G FKAS   + C  CP +S +  EAS  C C   
Sbjct: 247  MVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTG 306

Query: 342  YFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSH 401
            Y+R + DPP +ACT  PS PRN IS VNETS+ LEW PP +TGGR DV+Y I CKKC + 
Sbjct: 307  YYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRAD 366

Query: 402  AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVN 461
               C  C  +V ++PRQ GL    V +  L AHT YTF+I+A+NGVS  SP   Q+VSVN
Sbjct: 367  RRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVN 426

Query: 462  VTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSYTIIKS 520
            +TTNQAAPS V  + +      SI+LSW +P++PNGIIL+YEI+Y+EK+  E + ++ +S
Sbjct: 427  ITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARS 486

Query: 521  KETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSV 579
            +  T   +GL+P  VYV Q+RART AGYG FS +  F+T T     S  + Q+P+IA S 
Sbjct: 487  QTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSA 546

Query: 580  TVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHN 639
              GV+ +  ++ + +      C   RA S  AV          YS   Q       H+  
Sbjct: 547  AAGVVFVVSLVAISIV-----CSRKRAYSKEAV----------YSDKLQ-------HYST 584

Query: 640  GHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGK 699
            G    PG++ YIDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGEV  GRLKLPGK
Sbjct: 585  GRGS-PGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK 643

Query: 700  RELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENG 759
            RE+ VAIKTLK GY+EKQRRDFL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+MENG
Sbjct: 644  REIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENG 703

Query: 760  SLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDF 819
            +LD+FL++NDGQFTVIQLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNLVCKVSDF
Sbjct: 704  ALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDF 763

Query: 820  GLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGER 877
            GLSR L+DD  +  YT+  GGKIP+RWTAPEAIA+RKFTSASDVWSYGIVMWEV+S+GER
Sbjct: 764  GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER 823

Query: 878  PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIR 937
            PYW+M+NQDVI A+E+ YRLP PMDCPAAL+QLMLDCWQK+RNSRP+F EIVN LDK+IR
Sbjct: 824  PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIR 883

Query: 938  NPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAV 997
            NP+SLKT+   +   S  L + S     A+ +V +WL AIKM +Y + F+  G++S+  V
Sbjct: 884  NPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLV 943

Query: 998  AQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
             Q+T EDL R+G+TL GHQKKI+NS+  M+VQ+
Sbjct: 944  TQMTSEDLLRIGITLAGHQKKILNSIHSMRVQI 976


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 1088 bits (2813), Expect = 0.0
 Identities = 551/1009 (54%), Positives = 705/1009 (69%), Gaps = 45/1009 (4%)

Query: 35   PRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYA 94
            P   PL   LLL   L       + E  L+D++ V  +L W + P++GWEE+   DE   
Sbjct: 14   PGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMN 73

Query: 95   PIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMY 154
            PI TYQVC V E +QNNWL T +I      R+++ELKFT+RDCNS+P   G+CKETFN++
Sbjct: 74   PIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLF 133

Query: 155  YFESDDQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGF 210
            Y+E+D            EN Y+K+DTIA DESF+ LD G    ++NT+VR  GPLSK GF
Sbjct: 134  YYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGF 189

Query: 211  YLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV-TD 269
            YLAFQD GAC++L+SVR +YKKC S     A+FP+T+TGA+ + L+   G+C+ ++V   
Sbjct: 190  YLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVS 249

Query: 270  EPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSY 327
             P K++C+ +GEW+VP+G C C  G+E   K   C+ C PG +KA      C  CPP+S 
Sbjct: 250  VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSR 309

Query: 328  THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK 387
            T   A++ C C  +++R +SD    ACT  PS PR  ISNVNETS+ LEW  P D GGR 
Sbjct: 310  TTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRD 369

Query: 388  DVSYYIACKKCNSHAGV--CEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN 445
            D+ Y + CKKC+   G   C  C  +V ++PRQ GL    V +  LLAHT YTFE++AVN
Sbjct: 370  DLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVN 429

Query: 446  GVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIK 505
            GVS  SP   +Y +VN+TTNQAAPS V  ++    + +S++LSW  P+RPNG+IL+YE+K
Sbjct: 430  GVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMK 489

Query: 506  YFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565
            YFEK +  + T+  S+  ++  +GL+P + YV Q+RART AGYG +SR  EFETT    +
Sbjct: 490  YFEKSEGIASTVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGS 548

Query: 566  SSDQ--SQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGY 623
             + Q   Q+P+I  S T G++ +  V+ + +        C R                  
Sbjct: 549  GAQQLQEQLPLIVGSATAGLVFVVAVVVIAIV-------CLR------------------ 583

Query: 624  SKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGA 683
             K +   + E       +I  PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE VIGA
Sbjct: 584  -KQRHGSDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGA 641

Query: 684  GEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVV 743
            GEFGEVC GRLK PG+RE+ VAIKTLKVGYTE+QRRDFL EASIMGQFDHPNII LEGVV
Sbjct: 642  GEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVV 701

Query: 744  TKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAA 803
            TKS+PVMI+TE+MEN +LD+FL+ NDGQFTVIQLVGMLRGI+AGMKYLS+M YVHRDLAA
Sbjct: 702  TKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAA 761

Query: 804  RNILINSNLVCKVSDFGLSRVLEDDP-EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDV 861
            RNIL+NSNLVCKVSDFGLSR LEDDP +  YT+  GGKIPIRWTAPEAIA+RKFTSASDV
Sbjct: 762  RNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDV 821

Query: 862  WSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNS 921
            WSYGIVMWEV+SYGERPYW+M+NQDVI AVE+ YRLP PMDCP AL+QLMLDCW ++RN 
Sbjct: 822  WSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNL 881

Query: 922  RPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGR 981
            RPKF +IVN LDKLIRN +SLK + +A   +S  L + +      + +VG+WL+AIKMGR
Sbjct: 882  RPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGR 941

Query: 982  YTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
            Y E F+  G++S D VAQ+T EDL R+GVTL GHQKKI++S+Q+M++Q+
Sbjct: 942  YKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQM 990


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score = 1015 bits (2625), Expect = 0.0
 Identities = 524/1005 (52%), Positives = 680/1005 (67%), Gaps = 44/1005 (4%)

Query: 38   APLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPI 96
            A LW C L  AA     A+   EV LLD     G+LGW+  P   GW+ +  +  N  PI
Sbjct: 11   ALLWGCALAAAA-----AAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPI 64

Query: 97   HTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYF 156
            + Y VC VM  +Q+NWL T+W+    A RIFIELKFT+RDCNS PGG  +CKETFN+YY 
Sbjct: 65   YMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYA 124

Query: 157  ESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQD 216
            ESD   G N ++  + KIDTIA DE     D   R +KLN E R VGPL++KGFYLAFQD
Sbjct: 125  ESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQD 184

Query: 217  VGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTD---EPPK 273
            +GAC+AL+SVRVYYKKCP +++ LA FP+TI G+D+  L  V+G+CV+H+V     E P+
Sbjct: 185  IGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPR 244

Query: 274  MHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEAS 333
            MHC+ +GEWLVPIG+C+C+AGYE+    CQ C PGFFK       C +CP H+    E +
Sbjct: 245  MHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGA 304

Query: 334  TSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYI 393
            TSC CE+ +FR   DP +M CTRPPSAP    +      V L W PP D+GGR+D+ Y +
Sbjct: 305  TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364

Query: 394  ACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPG 453
             C++C   +G C  C   VRY     GL  TSV + DL  H NYTF +EA NGVS L   
Sbjct: 365  TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423

Query: 454  ARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET 513
            +R + + +V+ NQ  P  V    +G+ +  S+S+SW  P      + +YE+ Y +K    
Sbjct: 424  SRSFRTASVSINQTEPPKVR--LEGR-STTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480

Query: 514  SYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIP 573
            SY + +++  ++T + L P + Y+ Q++A T  G G  S+  EF+T      S + S   
Sbjct: 481  SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTL-----SPEGSGNL 535

Query: 574  VIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEE 633
             +   V VGV+LL V+ GV                        +  R    +A+Q PE+ 
Sbjct: 536  AVIGGVAVGVVLLLVLAGVGFF---------------------IHRRRKNQRARQSPED- 573

Query: 634  KMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGR 693
             ++F     +L  ++TY+DPHTYEDPNQAV +F  EI  SC+T ++VIGAGEFGEV  G 
Sbjct: 574  -VYFSKSE-QLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGM 631

Query: 694  LKLP-GKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIV 752
            LK   GK+E+PVAIKTLK GYTEKQR DFLGEA IMGQF H NII LEGV++K KP+MI+
Sbjct: 632  LKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMII 691

Query: 753  TEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNL 812
            TEYMENG+LD FL++ DG+F+V+QLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNL
Sbjct: 692  TEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNL 751

Query: 813  VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVV 872
            VCKVSDFGLSRVLEDDPEA YTT GGKIPIRWTAPEAI++RKFTSASDVWS+GIVMWEV+
Sbjct: 752  VCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVM 811

Query: 873  SYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 932
            +YGERPYWE++N +V+KA+ +G+RLP+PMDCP+A+YQLM+ CWQ+ER  RPKF +IV++L
Sbjct: 812  TYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSIL 871

Query: 933  DKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYS 992
            DKLIR P SLKTL +   RVS  L   S      +R+V EWLE+IKM +YTE FM  GY+
Sbjct: 872  DKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYT 931

Query: 993  SMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1037
            +++ V Q+T +D++R+GV L GHQK+I  SL  +K Q+    +P+
Sbjct: 932  AIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI 976


>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
          Length = 1008

 Score =  926 bits (2394), Expect = 0.0
 Identities = 481/1022 (47%), Positives = 668/1022 (65%), Gaps = 50/1022 (4%)

Query: 33   SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
            + P    L+ C + LC AL      P  + EV LLDS+    +LGW A P NGWEEI  V
Sbjct: 5    AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64

Query: 90   DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
            DE+  PI TYQVC V+E NQ+NWL T WIS     RIF+EL+FTLRDC+S+PG  GTCKE
Sbjct: 65   DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124

Query: 150  TFNMYYFESDDQNGRN---IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
            TFN+YY E++   GR    +  ++  KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 125  TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184

Query: 207  KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
            ++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T   +  S L+EV+G+CV HS
Sbjct: 185  RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244

Query: 267  VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPP 324
              +   PP+MHC A+GEWLVP+G+C C AG++E+   C+ C PGF+K SP    C  CP 
Sbjct: 245  EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPE 304

Query: 325  HSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLE--WIPPAD 382
            HS   E AST CVC+  Y R  +DPP+ +CTRPPSAPR+   +++ + + L   W+PPAD
Sbjct: 305  HSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPAD 364

Query: 383  TGGRKDVSYYIACKKCNSH--AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFE 440
            +GGR DV+Y + C +C     AG CE CG  V +LPRQ+GL+  +  ++ L     YT  
Sbjct: 365  SGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVR 424

Query: 441  IEAVNGVSDLSPGA-RQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEP---DRPN 496
            + A+NGVS  +  A   Y  V V+T   AP     +++ ++   S+SLSW+EP     P 
Sbjct: 425  VAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPG 484

Query: 497  GIILEYEIKYFEKDQ-ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV---FS 552
                EYEI+Y+EK Q E +Y+++K+   T+T   LKPA+ YVFQIRA +         F+
Sbjct: 485  ANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFN 544

Query: 553  RRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAV 612
               E +T    AAS  + Q P  A+ VTV  I   +V+G ++S                 
Sbjct: 545  PSIEVQTLGE-AASGSRDQSP--AIVVTVVTISALLVLGSVMSVLA-------------- 587

Query: 613  AHPSLIWR--CGYSKAKQDP-EEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKE 669
                 IWR  C Y K   D  +EE+++FH    K+P  RT++DP +  D  QAVH FAKE
Sbjct: 588  -----IWRRPCSYGKGGGDAHDEEELYFH---FKVPTRRTFLDPQSCGDLLQAVHLFAKE 639

Query: 670  IEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMG 729
            ++A  +T+ER +G G FGE+C G L+LPG++EL VA+  L+   ++ QR  FL EA  +G
Sbjct: 640  LDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699

Query: 730  QFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMK 789
            QFDH +I+ LEGVVT+   +MIVTEYM +G+LD FL++++GQ    QL+G+L G+++ MK
Sbjct: 700  QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMK 759

Query: 790  YLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEA 849
            YLS+MGYVHR LAAR++L++S+LVCK+S FG  R   D  EA YTT  G+ P  W APE 
Sbjct: 760  YLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPET 817

Query: 850  IAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQ 909
            + F  F+SASDVWS+GI+MWEV+++GERPYW+M+ QDVIKAVE+G+RLP P +CP  L++
Sbjct: 818  LQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHR 877

Query: 910  LMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRS 969
            LMLDCWQK+   RP+F +I ++L K++++P   K  +    R    LA+ +     ++ S
Sbjct: 878  LMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGS 937

Query: 970  VGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQ 1029
            VG WLEA+ + RY + F   GY S++AVA++T +DL  LG++L  H++ +++ +  ++ +
Sbjct: 938  VGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQAR 997

Query: 1030 LV 1031
            ++
Sbjct: 998  VL 999


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score =  917 bits (2371), Expect = 0.0
 Identities = 487/1007 (48%), Positives = 651/1007 (64%), Gaps = 53/1007 (5%)

Query: 44   LLLC-AALRTLLASPSNEVNLLDSRTVMGDLGWIAFPK--NGWEEIGEVDENYAPIHTYQ 100
            +LLC A+L   L     E  LL+++    DL W+ FP+    WEE+  +DE    + TY+
Sbjct: 5    VLLCWASLAAAL-----EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYE 59

Query: 101  VCKVMEQ-NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
            VC V     Q +WL T W+   GA  ++  L+FT+ +C SLP    +CKETF ++Y+ESD
Sbjct: 60   VCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESD 119

Query: 160  DQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQ 215
                  +     EN YIK+DT+AA+    +    +   K+N +   +GPLSK GFYLAFQ
Sbjct: 120  ADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQ 179

Query: 216  DVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVT--DEPPK 273
            D GAC+AL+S+ ++YKKC  +  +L  FP+T+       ++ V+GSCV  +V      P 
Sbjct: 180  DQGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPS 236

Query: 274  MHCSAEGEWLV-PIGKCMCKAGYE--EKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHE 330
            ++C  +G+W   P+  C C  G+E  E N  C+ C  G FK      SC  CP +S+++ 
Sbjct: 237  LYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNT 296

Query: 331  EASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVS 390
              S  C C   YFR  +DP    CT PPSAPR+ +S +N +S+ LEW  P ++GGR+D++
Sbjct: 297  IGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLT 356

Query: 391  YYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL 450
            Y + C++C    G C  CGG + + P    L    V++  L     YTFE+ A+NGVS L
Sbjct: 357  YALRCRECRP-GGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSL 415

Query: 451  SPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD 510
            + G   +  VNVTT++  P  V++++  + + +S+SL+W  P  P+G +L+YE+KY EK 
Sbjct: 416  ATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKG 475

Query: 511  QE--TSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSD 568
             E  +S   +K+ E      GLK  + Y+ Q+RAR+ AGYG F +    +T  +  +   
Sbjct: 476  AEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQ-LDESEGW 534

Query: 569  QSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQ 628
            + Q+ +IA +  VGV+L+ VVI V +              LC              K   
Sbjct: 535  REQLALIAGTAVVGVVLVLVVIVVAV--------------LCL------------RKQSN 568

Query: 629  DPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGE 688
              E E    H  ++   G + YIDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGE
Sbjct: 569  GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628

Query: 689  VCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKP 748
            VC GRLK PGK+E  VAIKTLK GYTE+QRR+FL EASIMGQF+HPNII LEGVVT S P
Sbjct: 629  VCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMP 688

Query: 749  VMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILI 808
            VMI+TE+MENG+LD+FL+ NDGQFTVIQLVGMLRGI++GM+YL++M YVHRDLAARNIL+
Sbjct: 689  VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILV 748

Query: 809  NSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGI 866
            NSNLVCKVSDFGLSR LE++  +  YT+  GGKIPIRWTAPEAIAFRKFTSASD WSYGI
Sbjct: 749  NSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGI 808

Query: 867  VMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFD 926
            VMWEV+S+GERPYW+M+NQDVI A+E+ YRLP P DCP +L+QLMLDCWQK+RN+RP+F 
Sbjct: 809  VMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFP 868

Query: 927  EIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIF 986
            ++V+ LDK+IRNP+SLK +   +   S+ L +       A+ SVGEWL AIKMGRY E F
Sbjct: 869  QVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESF 928

Query: 987  MENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNG 1033
               G+ S + V+Q++ EDL R+GVTL GHQKKI+ S+Q MK Q   G
Sbjct: 929  AAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQAKPG 975


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score =  789 bits (2037), Expect = 0.0
 Identities = 435/1009 (43%), Positives = 612/1009 (60%), Gaps = 53/1009 (5%)

Query: 36   RRAPLWT--CLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDEN 92
            RR PL     LLLCA L     + + EV L+D+    G+LGW+  P K+GW E  ++  N
Sbjct: 3    RRWPLGLGLVLLLCAPLPP--GARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LN 59

Query: 93   YAPIHTYQVCKVM-EQNQNNWLLTSWI-SNEGASRIFIELKFTLRDCNSLPGGLGT--CK 148
              P++ YQ C +   ++ ++WL ++WI   E ASR+ +EL+FT+RDC S PGG G   CK
Sbjct: 60   GTPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCK 119

Query: 149  ETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKK 208
            ETFN+ Y ESD   G  ++   + K+ T+AAD+SFT  DL    +KLN E   +G L+++
Sbjct: 120  ETFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRR 179

Query: 209  GFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS-V 267
            G YLAF + GAC+ALVSVRV+Y++CP  +  LA FPDT+ G   + L+EV+G+C+ H+  
Sbjct: 180  GLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARA 237

Query: 268  TDEP---PKMHCSAEGEWLVPIGKCMCKAGYEEKNG--TCQVCRPGFFKASPHIQSCGKC 322
            +  P   P+MHCS +GEWLVP+G+C C+ GYEE      C  C  G ++       C  C
Sbjct: 238  SPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTC 297

Query: 323  PPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPAD 382
            P  S    E +T C CE  ++R   + P +ACT PPSAPRN   + + T + L W PPAD
Sbjct: 298  PQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPAD 357

Query: 383  TGGRKDVSYYIACKKCNSHA---GVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTF 439
            TGGR+DV Y + C +C   A   G C+ CG  V + P   GL   +V +  L  + NYTF
Sbjct: 358  TGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTF 417

Query: 440  EIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQ-EPDRPNGI 498
             +EA NGVS L        SV+++   A      +++  K     + L+W     R  G 
Sbjct: 418  NVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGA 477

Query: 499  ILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFE 558
             L YE+    +D+E    ++   E  +    L+P + Y+ ++R  T  G G FS   EF 
Sbjct: 478  NLTYELHVLNQDEERYQMVL---EPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFR 534

Query: 559  TTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLI 618
            T+P  +      +I  +   + +G  LL   +G+L+  S       RA            
Sbjct: 535  TSPPVSRGLTGGEIVAVIFGLLLGAALL---LGILVFRS------RRAQ----------- 574

Query: 619  WRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIE 678
                  + +Q  + ++    +   KL  ++ Y+D   YEDP Q   +F +E++ + + ++
Sbjct: 575  ------RQRQQRQRDRATDVDREDKL-WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVD 627

Query: 679  RVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIH 738
             VIG GEFGEV  G L+LP +    VAIKTLK      Q  +FL EA+IMGQF HP+I+H
Sbjct: 628  TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687

Query: 739  LEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVH 798
            LEGVVTK KP+MI+TE+MENG+LD FL++ + Q    QLV ML+GI++GM YLS+  YVH
Sbjct: 688  LEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVH 747

Query: 799  RDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSA 858
            RDLAARNIL+N NL CKVSDFGL+R+L DD +  Y T+GGKIPIRWTAPEAIA R FT+A
Sbjct: 748  RDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTA 806

Query: 859  SDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKE 918
            SDVWS+GIVMWEV+S+G++PY EM+NQ+V+K++E+GYRLP P+DCPA LY+LM +CW  +
Sbjct: 807  SDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYD 866

Query: 919  RNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIK 978
            R  RP F ++   L++L+ NP SL+T+ N   R++  L   S      YR+V EWLE+I+
Sbjct: 867  RARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIR 926

Query: 979  MGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMK 1027
            M RY   F   G  +M+ V ++T EDL ++G+TL GHQK+I+ S+Q  K
Sbjct: 927  MKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFK 975


>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
          Length = 1021

 Score =  756 bits (1953), Expect = 0.0
 Identities = 411/1038 (39%), Positives = 603/1038 (58%), Gaps = 91/1038 (8%)

Query: 40   LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
            LW  LL+ + L         E  LLD+     ++GW+ +P  GW+E+  +D+      T+
Sbjct: 20   LWVLLLVSSVLAL-------EEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTF 72

Query: 100  QVCKVMEQ----NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYY 155
            + C V        Q+NWL T ++   GA R  I L F++R C+SL    GTC+ETF +YY
Sbjct: 73   EACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYY 132

Query: 156  FESDDQNGRNIKENQYIK----IDTIAADESFTELD-----------------LGDRV-M 193
             ++++ +  +   + ++K    +DTIAADESF                      G R  +
Sbjct: 133  RQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGL 192

Query: 194  KLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDT-ITGADS 252
            +LN + R  GPL+++GFY+AFQD GAC+ALV+VR++   CP+V+R  A FP+T  +GA  
Sbjct: 193  QLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGG 252

Query: 253  SQLLEVSGSCVNHSVTDE----------PPKMHCSAEGEWLVPIGKCMCKAGYEEKNG-- 300
            + L+   G+CV H+  +E          PP++HC+ EG+W+V +G C C+ GY+   G  
Sbjct: 253  ASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDK 312

Query: 301  TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
             CQ C  G +K+S     C  CP  S+    A+  C C + ++R  SDPP   CT PPSA
Sbjct: 313  ACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSA 372

Query: 361  PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSH-------AGVCEECGGHVR 413
            P+     V  +++ L W  P + GGR D+ + + CK+C           G C  C   V 
Sbjct: 373  PQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVH 432

Query: 414  YLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVT 473
            + PRQ GL  + V++  L AH  Y  E++AVNGVS+LSP   Q  ++NV+T+   PS V 
Sbjct: 433  FDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVP 492

Query: 474  NVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKET-TITAEGLKP 532
             V +   A NSI++SW +PD+ NG IL+Y+++Y+++ ++ S++   + ET T T   L P
Sbjct: 493  VVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSP 552

Query: 533  ASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGV 592
              +Y FQ+RARTAAG+G +  +  F+T P    SS   Q+P   +S+ +G IL A+   +
Sbjct: 553  GHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSS---QLPE-RLSLVIGSILGALAFLL 608

Query: 593  LLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYID 652
            L            A ++ AV         GY++  Q      +          GV+ YID
Sbjct: 609  LA-----------AITVLAVVFQRKRRGTGYTEQLQQYSSPGL----------GVKYYID 647

Query: 653  PHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVG 712
            P TYEDP QA+ E A+E++ + I IE VIG G FGEV  GRL+  G+RE  VAI+ L  G
Sbjct: 648  PSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAG 707

Query: 713  YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQF 772
              E  +  FLG A+++GQF HPNI+ LEGVVTKS+P+M++TE+ME G LD+FL++ +GQF
Sbjct: 708  GAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQF 767

Query: 773  TVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAA 832
            + +QLV M RG++A M+YLS   +VHR L+A ++L+NS+LVCKV+  G            
Sbjct: 768  SSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG------------ 815

Query: 833  YTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 892
            ++ +G    +RW APE IA  K T++SDVWS+GI+MWEV+SYGERPYW+M+ Q+V+ A+E
Sbjct: 816  HSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIE 875

Query: 893  EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRV 952
            + +RLP P  CP  L+ LMLD WQK+R  RP FD++V   DK+IR P +L+   +   R 
Sbjct: 876  QEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERP 935

Query: 953  SNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTL 1012
            S  L     L      S   WL AI +  Y + F + G  +   VAQ++LEDL  LG+TL
Sbjct: 936  SQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITL 995

Query: 1013 VGHQKKIMNSLQEMKVQL 1030
             GHQKK+++ +Q ++  L
Sbjct: 996  AGHQKKLLHHIQLLQQHL 1013


>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
           sapiens]
          Length = 539

 Score =  737 bits (1902), Expect = 0.0
 Identities = 339/522 (64%), Positives = 423/522 (81%), Gaps = 5/522 (0%)

Query: 44  LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
           LL C+ L +   L+  PSNEVNLLDS+T+ G+LGWI++P +GWEEI  VDE+Y PI TYQ
Sbjct: 10  LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69

Query: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
           VC VM+ +QNNWL T+W+    A +I++ELKFTLRDCNS+P  LGTCKETFN+YY ESDD
Sbjct: 70  VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129

Query: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
            +G   +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189

Query: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
           +ALVSVRVY+KKCP  V++LA+FPDT+   DS  L+EV GSCVN+S  ++PP+M+CS EG
Sbjct: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248

Query: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
           EWLVPIGKC C AGYEE+   CQ CRPGF+KA      C KCPPHS T E+ S +C CE 
Sbjct: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308

Query: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
           +YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W  P DTGGRKDV++ I CKKC  
Sbjct: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368

Query: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
           +   CE C  +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS   RQ+ +V
Sbjct: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428

Query: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
           ++TTNQAAPSPV  +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488

Query: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP 561
           ++ T +T   LKP ++YVFQIRARTAAGYG  SR+FEFET+P
Sbjct: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530


>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
           sapiens]
          Length = 495

 Score =  555 bits (1430), Expect = e-158
 Identities = 253/428 (59%), Positives = 322/428 (75%), Gaps = 1/428 (0%)

Query: 40  LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
           LW  +   AA  T +++   EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 12  LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70

Query: 100 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
           QVC VM  NQNNWL TSW+  +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 71  QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130

Query: 160 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
              G + +E+Q++KIDTIAADESFT  DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190

Query: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
           C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS   + PKM+CSAE
Sbjct: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250

Query: 280 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
           GEWLVPIGKC+C AGYEE+   C  C  GF+K++P  Q C +CPPHS++   A+ +C C+
Sbjct: 251 GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310

Query: 340 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
             Y+R   DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y   C++C 
Sbjct: 311 LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370

Query: 400 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
                CE CG   R++P+Q+ L   S+++ +LLAH NY+F IEAVNGVSDLSP  R+   
Sbjct: 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430

Query: 460 VNVTTNQA 467
           VN+TTNQA
Sbjct: 431 VNITTNQA 438


>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
          Length = 295

 Score =  318 bits (814), Expect = 2e-86
 Identities = 158/279 (56%), Positives = 200/279 (71%), Gaps = 8/279 (2%)

Query: 33  SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
           + P    L+ C + LC AL      P  + EV LLDS+    +LGW A P NGWEEI  V
Sbjct: 5   AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64

Query: 90  DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
           DE+  PI TYQVC V+E NQ+NWL T WIS     RIF+EL+FTLRDC+S+PG  GTCKE
Sbjct: 65  DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124

Query: 150 TFNMYYFESDDQNGR---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
           TFN+YY E++   GR    +  ++  KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184

Query: 207 KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
           ++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T   +  S L+EV+G+CV HS
Sbjct: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244

Query: 267 VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQ 303
             +   PP+MHC A+GEWLVP+G+C C AG++E+   C+
Sbjct: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283


>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
          Length = 526

 Score =  229 bits (583), Expect = 1e-59
 Identities = 120/277 (43%), Positives = 175/277 (63%), Gaps = 12/277 (4%)

Query: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 718
           P +   + A EI    + +E+ +GAG+FGEV          +   VA+KT+K G    + 
Sbjct: 246 PQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYN----KHTKVAVKTMKPGSMSVEA 301

Query: 719 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 777
             FL EA++M    H  ++ L  VVTK +P+ I+TE+M  GSL  FLK ++G    + +L
Sbjct: 302 --FLAEANVMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKL 358

Query: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 836
           +     I+ GM ++    Y+HRDL A NIL++++LVCK++DFGL+RV+ED+    YT R 
Sbjct: 359 IDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE---YTARE 415

Query: 837 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 896
           G K PI+WTAPEAI F  FT  SDVWS+GI++ E+V+YG  PY  M+N +VI+A+E GYR
Sbjct: 416 GAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYR 475

Query: 897 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
           +P P +CP  LY +M+ CW+     RP F+ I ++LD
Sbjct: 476 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512


>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform B [Homo sapiens]
          Length = 491

 Score =  226 bits (577), Expect = 7e-59
 Identities = 121/277 (43%), Positives = 175/277 (63%), Gaps = 11/277 (3%)

Query: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 718
           P +   + A EI    I + + +GAG+FGEV  G      K    VA+KTLK G    Q 
Sbjct: 210 PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA 265

Query: 719 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 777
             FL EA++M    H  ++ L  VVT+ +P+ I+TEYM  GSL  FLK ++G   ++ +L
Sbjct: 266 --FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKL 323

Query: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 836
           +     I+ GM Y+    Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+    YT R 
Sbjct: 324 IDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTARE 380

Query: 837 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 896
           G K PI+WTAPEAI F  FT  SDVWS+GI+++E+V+YG+ PY   TN DV+ A+ +GYR
Sbjct: 381 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYR 440

Query: 897 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
           +P   +CP  LY +M  CW+++   RP FD + ++LD
Sbjct: 441 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLD 477


>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform A [Homo sapiens]
          Length = 512

 Score =  226 bits (577), Expect = 7e-59
 Identities = 121/277 (43%), Positives = 175/277 (63%), Gaps = 11/277 (3%)

Query: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 718
           P +   + A EI    I + + +GAG+FGEV  G      K    VA+KTLK G    Q 
Sbjct: 231 PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA 286

Query: 719 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 777
             FL EA++M    H  ++ L  VVT+ +P+ I+TEYM  GSL  FLK ++G   ++ +L
Sbjct: 287 --FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKL 344

Query: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 836
           +     I+ GM Y+    Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+    YT R 
Sbjct: 345 IDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTARE 401

Query: 837 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 896
           G K PI+WTAPEAI F  FT  SDVWS+GI+++E+V+YG+ PY   TN DV+ A+ +GYR
Sbjct: 402 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYR 461

Query: 897 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
           +P   +CP  LY +M  CW+++   RP FD + ++LD
Sbjct: 462 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLD 498


>gi|4503787 fyn-related kinase [Homo sapiens]
          Length = 505

 Score =  223 bits (568), Expect = 7e-58
 Identities = 116/275 (42%), Positives = 167/275 (60%), Gaps = 8/275 (2%)

Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
           EI+ + I + + +G+G+FGEV  G          PVA+KTLK G  +    DFL EA IM
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWN----NTTPVAVKTLKPGSMDPN--DFLREAQIM 281

Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-QFTVIQLVGMLRGISAG 787
               HP +I L  V T   P+ I+TE M +GSL  +L+ + G +  + Q V M   +++G
Sbjct: 282 KNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASG 341

Query: 788 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGG-KIPIRWTA 846
           M YL    Y+HRDLAARN+L+  + + KV+DFGL+RV + D E  Y +R   K+P++WTA
Sbjct: 342 MAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTA 401

Query: 847 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 906
           PEAI   KF+  SDVWS+GI+++E+++YG+ PY  MT   VI+ + + YRLP P +CP  
Sbjct: 402 PEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQ 461

Query: 907 LYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSS 941
            Y +ML+CW  E   RP F+ +   L+      SS
Sbjct: 462 FYNIMLECWNAEPKERPTFETLRWKLEDYFETDSS 496


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score =  223 bits (567), Expect = 1e-57
 Identities = 126/281 (44%), Positives = 176/281 (62%), Gaps = 12/281 (4%)

Query: 655 TYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYT 714
           T +   Q + + A EI    + +E  +G G FGEV  G      K    VAIKTLK G  
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312

Query: 715 EKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV 774
             +   FL EA IM +  H  ++ L  VV++ +P+ IVTE+M  GSL  FLK+ DG++  
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLK 369

Query: 775 I-QLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 833
           + QLV M   I+ GM Y+  M Y+HRDL A NIL+  NLVCK++DFGL+R++ED+    Y
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---Y 426

Query: 834 TTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 892
           T R G K PI+WTAPEA  + +FT  SDVWS+GI+  E+V+ G  PY  M N++V++ VE
Sbjct: 427 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE 486

Query: 893 EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
            GYR+P P  CP +L++LM  CW+K+ + RP F+ I + L+
Sbjct: 487 RGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527


>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
          Length = 1074

 Score =  222 bits (566), Expect = 1e-57
 Identities = 116/268 (43%), Positives = 161/268 (60%), Gaps = 3/268 (1%)

Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
           EI+   I + R IG G+FG+V  G    P    L VAIKT K   ++  R  FL EA  M
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497

Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGM 788
            QFDHP+I+ L GV+T++ PV I+ E    G L +FL+       +  L+     +S  +
Sbjct: 498 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556

Query: 789 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPE 848
            YL    +VHRD+AARN+L++SN   K+ DFGLSR +ED     Y    GK+PI+W APE
Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPE 614

Query: 849 AIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALY 908
           +I FR+FTSASDVW +G+ MWE++ +G +P+  + N DVI  +E G RLP P +CP  LY
Sbjct: 615 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLY 674

Query: 909 QLMLDCWQKERNSRPKFDEIVNMLDKLI 936
            LM  CW  + + RP+F E+   L  ++
Sbjct: 675 SLMTKCWAYDPSRRPRFTELKAQLSTIL 702


>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
          Length = 1052

 Score =  222 bits (566), Expect = 1e-57
 Identities = 116/268 (43%), Positives = 161/268 (60%), Gaps = 3/268 (1%)

Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
           EI+   I + R IG G+FG+V  G    P    L VAIKT K   ++  R  FL EA  M
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475

Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGM 788
            QFDHP+I+ L GV+T++ PV I+ E    G L +FL+       +  L+     +S  +
Sbjct: 476 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534

Query: 789 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPE 848
            YL    +VHRD+AARN+L++SN   K+ DFGLSR +ED     Y    GK+PI+W APE
Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPE 592

Query: 849 AIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALY 908
           +I FR+FTSASDVW +G+ MWE++ +G +P+  + N DVI  +E G RLP P +CP  LY
Sbjct: 593 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLY 652

Query: 909 QLMLDCWQKERNSRPKFDEIVNMLDKLI 936
            LM  CW  + + RP+F E+   L  ++
Sbjct: 653 SLMTKCWAYDPSRRPRFTELKAQLSTIL 680


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score =  222 bits (565), Expect = 2e-57
 Identities = 118/267 (44%), Positives = 171/267 (64%), Gaps = 12/267 (4%)

Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
           EI    + + + +G G+FGEV  G      K    VAIKTLK G    +   FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318

Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QLVGMLRGISAG 787
            +  H  ++ L  VV++ +P+ IVTEYM  GSL  FLK  +G+   +  LV M   ++AG
Sbjct: 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377

Query: 788 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR-GGKIPIRWTA 846
           M Y+  M Y+HRDL + NIL+ + L+CK++DFGL+R++ED+    YT R G K PI+WTA
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTA 434

Query: 847 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 906
           PEA  + +FT  SDVWS+GI++ E+V+ G  PY  M N++V++ VE GYR+P P DCP +
Sbjct: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 494

Query: 907 LYQLMLDCWQKERNSRPKFDEIVNMLD 933
           L++LM+ CW+K+   RP F+ + + L+
Sbjct: 495 LHELMIHCWKKDPEERPTFEYLQSFLE 521


>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  221 bits (562), Expect = 4e-57
 Identities = 122/283 (43%), Positives = 175/283 (61%), Gaps = 12/283 (4%)

Query: 653 PHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVG 712
           P   + P +   E   E+    + +   +GAG+FGEV  G      K    VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278

Query: 713 YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-Q 771
                   FL EA++M Q  H  ++ L  VVT+ +P+ I+TEYMENGSL  FLK   G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIK 335

Query: 772 FTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEA 831
            T+ +L+ M   I+ GM ++ +  Y+HRDL A NIL++  L CK++DFGL+R++ED+   
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393

Query: 832 AYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKA 890
            YT R G K PI+WTAPEAI +  FT  SDVWS+GI++ E+V++G  PY  MTN +VI+ 
Sbjct: 394 -YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN 452

Query: 891 VEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
           +E GYR+  P +CP  LYQLM  CW++    RP FD + ++L+
Sbjct: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495


>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  221 bits (562), Expect = 4e-57
 Identities = 122/283 (43%), Positives = 175/283 (61%), Gaps = 12/283 (4%)

Query: 653 PHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVG 712
           P   + P +   E   E+    + +   +GAG+FGEV  G      K    VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278

Query: 713 YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-Q 771
                   FL EA++M Q  H  ++ L  VVT+ +P+ I+TEYMENGSL  FLK   G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIK 335

Query: 772 FTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEA 831
            T+ +L+ M   I+ GM ++ +  Y+HRDL A NIL++  L CK++DFGL+R++ED+   
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393

Query: 832 AYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKA 890
            YT R G K PI+WTAPEAI +  FT  SDVWS+GI++ E+V++G  PY  MTN +VI+ 
Sbjct: 394 -YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN 452

Query: 891 VEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
           +E GYR+  P +CP  LYQLM  CW++    RP FD + ++L+
Sbjct: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  220 bits (561), Expect = 5e-57
 Identities = 125/281 (44%), Positives = 172/281 (61%), Gaps = 12/281 (4%)

Query: 655 TYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYT 714
           T +   Q + + A EI    + +E  +G G FGEV  G      +    VAIKTLK G  
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305

Query: 715 EKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV 774
             +   FL EA +M +  H  ++ L  VV++ +P+ IVTEYM  GSL  FLK   G++  
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLR 362

Query: 775 I-QLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 833
           + QLV M   I++GM Y+  M YVHRDL A NIL+  NLVCKV+DFGL+R++ED+    Y
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---Y 419

Query: 834 TTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 892
           T R G K PI+WTAPEA  + +FT  SDVWS+GI++ E+ + G  PY  M N++V+  VE
Sbjct: 420 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 479

Query: 893 EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
            GYR+P P +CP +L+ LM  CW+KE   RP F+ +   L+
Sbjct: 480 RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,582,207
Number of Sequences: 37866
Number of extensions: 2044290
Number of successful extensions: 9536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 607
Number of HSP's successfully gapped in prelim test: 355
Number of HSP's that attempted gapping in prelim test: 5711
Number of HSP's gapped (non-prelim): 2184
length of query: 1037
length of database: 18,247,518
effective HSP length: 112
effective length of query: 925
effective length of database: 14,006,526
effective search space: 12956036550
effective search space used: 12956036550
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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