Guide to the Human Genome
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Search of human proteins with 21955170

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21955170 single stranded DNA binding protein 3 isoform a
[Homo sapiens]
         (388 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21955170 single stranded DNA binding protein 3 isoform a [Hom...   846   0.0  
gi|21314684 single stranded DNA binding protein 3 isoform b [Hom...   790   0.0  
gi|58218981 single stranded DNA binding protein 3 isoform c [Hom...   770   0.0  
gi|40787999 single-stranded DNA binding protein 2 [Homo sapiens]      639   0.0  
gi|14249150 single stranded DNA binding protein 4 isoform a [Hom...   607   e-174
gi|58218984 single stranded DNA binding protein 4 isoform b [Hom...   561   e-160
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    107   1e-23
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    92   1e-18
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      87   3e-17
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    87   3e-17
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      86   7e-17
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               84   2e-16
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       84   2e-16
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    84   2e-16
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    84   2e-16
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    84   2e-16
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    83   5e-16
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    82   8e-16
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           82   8e-16
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 81   1e-15
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    80   3e-15
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                79   5e-15
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       79   9e-15
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               78   2e-14
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    77   2e-14
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    77   2e-14
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      76   5e-14
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        76   5e-14
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    75   1e-13
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          75   1e-13

>gi|21955170 single stranded DNA binding protein 3 isoform a [Homo
           sapiens]
          Length = 388

 Score =  846 bits (2186), Expect = 0.0
 Identities = 388/388 (100%), Positives = 388/388 (100%)

Query: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60
           MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH
Sbjct: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60

Query: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120
           SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF
Sbjct: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120

Query: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL 180
           FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL
Sbjct: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL 180

Query: 181 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 240
           LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG
Sbjct: 181 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 240

Query: 241 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 300
           PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP
Sbjct: 241 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 300

Query: 301 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 360
           VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT
Sbjct: 301 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 360

Query: 361 PRDDGELGGNFLHSFQNDNYSPSMTMSV 388
           PRDDGELGGNFLHSFQNDNYSPSMTMSV
Sbjct: 361 PRDDGELGGNFLHSFQNDNYSPSMTMSV 388


>gi|21314684 single stranded DNA binding protein 3 isoform b [Homo
           sapiens]
          Length = 368

 Score =  790 bits (2041), Expect = 0.0
 Identities = 368/388 (94%), Positives = 368/388 (94%), Gaps = 20/388 (5%)

Query: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60
           MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH
Sbjct: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60

Query: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120
           SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF
Sbjct: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120

Query: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL 180
           FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP                    PGGVPGTQPL
Sbjct: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQP--------------------PGGVPGTQPL 160

Query: 181 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 240
           LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG
Sbjct: 161 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 220

Query: 241 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 300
           PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP
Sbjct: 221 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 280

Query: 301 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 360
           VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT
Sbjct: 281 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 340

Query: 361 PRDDGELGGNFLHSFQNDNYSPSMTMSV 388
           PRDDGELGGNFLHSFQNDNYSPSMTMSV
Sbjct: 341 PRDDGELGGNFLHSFQNDNYSPSMTMSV 368


>gi|58218981 single stranded DNA binding protein 3 isoform c [Homo
           sapiens]
          Length = 361

 Score =  770 bits (1988), Expect = 0.0
 Identities = 361/388 (93%), Positives = 361/388 (93%), Gaps = 27/388 (6%)

Query: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60
           MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH
Sbjct: 1   MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLH 60

Query: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120
           SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF
Sbjct: 61  SWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGF 120

Query: 121 FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL 180
           FQ                           PFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL
Sbjct: 121 FQ---------------------------PFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL 153

Query: 181 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 240
           LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG
Sbjct: 154 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMG 213

Query: 241 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 300
           PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP
Sbjct: 214 PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 273

Query: 301 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 360
           VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT
Sbjct: 274 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 333

Query: 361 PRDDGELGGNFLHSFQNDNYSPSMTMSV 388
           PRDDGELGGNFLHSFQNDNYSPSMTMSV
Sbjct: 334 PRDDGELGGNFLHSFQNDNYSPSMTMSV 361


>gi|40787999 single-stranded DNA binding protein 2 [Homo sapiens]
          Length = 361

 Score =  639 bits (1648), Expect = 0.0
 Identities = 303/391 (77%), Positives = 329/391 (84%), Gaps = 33/391 (8%)

Query: 1   MFAKGKG--SAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF 58
           M+ KGK   SAVPSD QAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF
Sbjct: 1   MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF 60

Query: 59  LHSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPP 118
           LHSWWCVFWDLYCAAPERR+TCEHSSEAKAFHDYSAAAAPSPVLGNIPP DGMP GP+PP
Sbjct: 61  LHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPP 120

Query: 119 GFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQ 178
           GFF                           QPFMSPRY GGPRPP+R+ NQ  GGVPG+Q
Sbjct: 121 GFF---------------------------QPFMSPRYPGGPRPPLRIPNQALGGVPGSQ 153

Query: 179 PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPGI 237
           PLLP+ MDPTRQQGHPNMGG MQRM PPRGM P+  GPQNYG  MRPP N+L GP MPG+
Sbjct: 154 PLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPL--GPQNYGGAMRPPLNALGGPGMPGM 211

Query: 238 NMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTM 297
           NMGPG GRPWPNP +ANSIPYSS+SPG YVGPPGGGGPPGTPIMPSPADSTNS DN+YT+
Sbjct: 212 NMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTL 271

Query: 298 INPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNP 357
           +N VPPG +R NFPMGPGSDGPMGG+GGME HHMNGSLGSGD+D + KNSPNN+S +SN 
Sbjct: 272 MNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMS-LSNQ 330

Query: 358 PGTPRDDGELGGNFLHSFQNDNYSPSMTMSV 388
           PGTPRDDGE+GGNFL+ FQ+++YSPSMTMSV
Sbjct: 331 PGTPRDDGEMGGNFLNPFQSESYSPSMTMSV 361


>gi|14249150 single stranded DNA binding protein 4 isoform a [Homo
           sapiens]
          Length = 385

 Score =  607 bits (1566), Expect = e-174
 Identities = 285/394 (72%), Positives = 329/394 (83%), Gaps = 15/394 (3%)

Query: 1   MFAKG-KGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFL 59
           M+AKG KGSAVPSD QAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60

Query: 60  HSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPG 119
           HSWWCVFWDLYCAAP+RR+ CEHS EAKAF DYSAAAAPSPV+G++ P D M  G +  G
Sbjct: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120

Query: 120 FFQGPPGSQPSPHAQPPPHNPSS-MMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQ 178
           FFQGPPGSQPS      PHNP++ MMGPH QPFMSPR+ GGPRP +RM +QPP G+PG+Q
Sbjct: 121 FFQGPPGSQPS------PHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ 174

Query: 179 PLLPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPG 236
           PLLP +M+P+ R QGHP+MGG MQR+ PPRGM  +  GPQ+YG GMRPPPNSL GP +P 
Sbjct: 175 PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASV--GPQSYGGGMRPPPNSLAGPGLPA 232

Query: 237 INMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYT 296
           +NMGPG   PW +P S NSIPYSSSSPG+Y GPPGGGGPPGTPIMPSP DSTNSS+N+YT
Sbjct: 233 MNMGPGVRGPWASP-SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYT 291

Query: 297 MINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISN 356
           ++NP+  G  R+NFP+GPG +GPM  M  MEPHH+NGSLGSGD+DGLPK+SP  ++G+SN
Sbjct: 292 IMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSN 351

Query: 357 PPGTPRDDGEL--GGNFLHSFQNDNYSPSMTMSV 388
            PGTPRDDGE+   G FLH F +++YSP MTMSV
Sbjct: 352 APGTPRDDGEMAAAGTFLHPFPSESYSPGMTMSV 385


>gi|58218984 single stranded DNA binding protein 4 isoform b [Homo
           sapiens]
          Length = 363

 Score =  561 bits (1445), Expect = e-160
 Identities = 267/393 (67%), Positives = 309/393 (78%), Gaps = 35/393 (8%)

Query: 1   MFAKG-KGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFL 59
           M+AKG KGSAVPSD QAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60

Query: 60  HSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPG 119
           HSWWCVFWDLYCAAP+RR+ CEHS EAKAF DYSAAAAPSPV+G++ P D M  G +  G
Sbjct: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120

Query: 120 FFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQP 179
           FF                           QPFMSPR+ GGPRP +RM +QPP G+PG+QP
Sbjct: 121 FF---------------------------QPFMSPRFPGGPRPTLRMPSQPPAGLPGSQP 153

Query: 180 LLPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPGI 237
           LLP +M+P+ R QGHP+MGG MQR+ PPRGM  +  GPQ+YG GMRPPPNSL GP +P +
Sbjct: 154 LLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASV--GPQSYGGGMRPPPNSLAGPGLPAM 211

Query: 238 NMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTM 297
           NMGPG   PW +P S NSIPYSSSSPG+Y GPPGGGGPPGTPIMPSP DSTNSS+N+YT+
Sbjct: 212 NMGPGVRGPWASP-SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTI 270

Query: 298 INPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNP 357
           +NP+  G  R+NFP+GPG +GPM  M  MEPHH+NGSLGSGD+DGLPK+SP  ++G+SN 
Sbjct: 271 MNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNA 330

Query: 358 PGTPRDDGEL--GGNFLHSFQNDNYSPSMTMSV 388
           PGTPRDDGE+   G FLH F +++YSP MTMSV
Sbjct: 331 PGTPRDDGEMAAAGTFLHPFPSESYSPGMTMSV 363


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  107 bits (268), Expect = 1e-23
 Identities = 101/313 (32%), Positives = 113/313 (36%), Gaps = 38/313 (12%)

Query: 83  SSEAKAFHDYSAAAAPSPVLGN---IPPNDGMP--GGPIPPGFFQGPP---GSQPSPHAQ 134
           SS      D S   +PS + GN    PP  G    G P PPG  QGPP   G+QP    Q
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQP----Q 69

Query: 135 PPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHP 194
            PP  P    GP  Q    P+   GP PP +    PP G     P  P    P + QG P
Sbjct: 70  GPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQGPPPQGDKSRSPRSP----PGKPQGPP 122

Query: 195 NMGGSMQRMNPPRGMGPMGPGPQ--NYGSGMRPPPNSLGPAMPGINMGPGAGRP-----W 247
             GG+  +  PP    P GP PQ  N   G  PP    GP   G N    +  P      
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182

Query: 248 PNPNSANSIPYSSSSPGTYVGPPGGGG-------PPGTPIMPSPADSTNSSDNIYTMINP 300
           P P   N        PG   GPP  GG       PPG P  P P     S         P
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242

Query: 301 VPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLG---SGDIDGLPKNSPNNISGISNP 357
             P     N P GP    P G   G  P   N   G    G   G P    +      +P
Sbjct: 243 QGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300

Query: 358 PGTPRDDGELGGN 370
           PG P+     GGN
Sbjct: 301 PGKPQGPPPQGGN 313



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 76/234 (32%), Positives = 85/234 (36%), Gaps = 40/234 (17%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPP--GSQPSPHAQPPPHNPSSMMGPHSQPFMSPR 155
           P    G  P     P GP PPG  QGPP  G   S  A+ PP  P    GP  Q    P+
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ---GPPPQGGNQPQ 254

Query: 156 YAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 215
             G P PP +    PP G  G +P  P    P + QG P  GGS  R +      P GP 
Sbjct: 255 --GPPPPPGKPQGPPPQG--GNKPQGPPP--PGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308

Query: 216 PQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGG- 274
           PQ       PPP       PG   GP        P    + P     PG   GPP  GG 
Sbjct: 309 PQGGNQPQGPPP------PPGKPQGP--------PPQGGNKPQGPPPPGKPQGPPPQGGS 354

Query: 275 -------PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG 321
                  PPG P  P   +  N          P PP G     P  P +  P G
Sbjct: 355 KSRSARSPPGKPQGPPQQEGNNPQ-------GPPPPAGGNPQQPQAPPAGQPQG 401



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 64/197 (32%), Positives = 73/197 (37%), Gaps = 25/197 (12%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPP-GFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPF 151
           SA + P    G  P     P GP PP G  QGPP    +    PPP  P    GP  Q  
Sbjct: 234 SARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKPQGPPPQGG 291

Query: 152 MSPRYAGGPR-----PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPP 206
              R +  P      PP + GNQP G  P           P + QG P  GG+  +  PP
Sbjct: 292 SKSRSSRSPPGKPQGPPPQGGNQPQGPPP----------PPGKPQGPPPQGGNKPQGPPP 341

Query: 207 RGMGPMGPGPQNYG---SGMRPPPNSLGPAMPGINMGPGAGRP-WPNPNSANSIPYSSSS 262
            G  P GP PQ      S   PP    GP     N   G   P   NP    + P  +  
Sbjct: 342 PGK-PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP--AGQ 398

Query: 263 PGTYVGPPGGGGPPGTP 279
           P     PP GG P   P
Sbjct: 399 PQGPPRPPQGGRPSRPP 415


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 94/305 (30%), Positives = 109/305 (35%), Gaps = 45/305 (14%)

Query: 83  SSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSS 142
           SS      D S   +PS + GN       P GP P G      G++P    Q PP  P  
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGN-------PQGPSPQG------GNKP----QGPPPPPGK 56

Query: 143 MMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQR 202
             GP  Q    P+   GP PP +    PP G     P  P    P + QG P  GG+  +
Sbjct: 57  PQGPPPQGGNKPQ---GPPPPGKPQGPPPQGDKSRSPRSP----PGKPQGPPPQGGNQPQ 109

Query: 203 MNPPRGMGPMGPGPQ--NYGSGMRPPPNSLGPAMPGIN----MGPGAGRPWPNPNSANSI 256
             PP    P GP PQ  N   G  PP    GP   G        P      P P   N  
Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 169

Query: 257 PYSSSSPGTYVGPPGGGG-------PPGTPIMPSP-ADSTNSSDNIYTMINPVPPGGSRS 308
                 PG   GPP  GG       PPG P  P P  D + SS +        PP G   
Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG--G 227

Query: 309 NFPMGPGSDGPMGGMGGMEPHHMNGSLG---SGDIDGLPKNSPNNISGISNPPGTPRDDG 365
           N P GP    P G   G  P   N   G    G   G P    +      +PPG P+   
Sbjct: 228 NQPQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP 285

Query: 366 ELGGN 370
           +  GN
Sbjct: 286 QQEGN 290



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 79/241 (32%), Positives = 87/241 (36%), Gaps = 41/241 (17%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPS-PHAQPPPHNPSSMMGPHSQPFMSPRY 156
           P P  GN P      G P PPG  QGPP    + P   PPP  P     P      SPR 
Sbjct: 100 PPPQGGNQPQ-----GPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQGDKSRSPRS 153

Query: 157 AGGPR--PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
             G    PP + GNQP G  P           P + QG P  GG   +  PP G  P GP
Sbjct: 154 PPGKPQGPPPQGGNQPQGPPP----------PPGKPQGPPPQGGKKPQGPPPPGK-PQGP 202

Query: 215 GPQN--YGSGMRPPPNSLGPAMPGINMGPGA----GRPWPNPNSANSIPYSSSSPGTYVG 268
            PQ     S   PP    GP   G N   G     G+P   P    + P     PG   G
Sbjct: 203 PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 262

Query: 269 PPGGGG--------PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 320
           PP  GG        PPG P  P   +  N          P PP G     P  P +  P 
Sbjct: 263 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ-------GPPPPAGGNPQQPQAPPAGQPQ 315

Query: 321 G 321
           G
Sbjct: 316 G 316



 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 82/255 (32%), Positives = 90/255 (35%), Gaps = 43/255 (16%)

Query: 98  PSPVLGNIP---PNDGMPGGP-----------IPPGFFQGPP---GSQPSPHAQPPPHNP 140
           P P  GN P   P  G P GP            PPG  QGPP   G+QP    Q PP  P
Sbjct: 60  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP----QGPPPPP 115

Query: 141 SSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM 200
               GP  Q    P+   GP PP +    PP G     P  P    P + QG P  GG+ 
Sbjct: 116 GKPQGPPPQGGNRPQ---GPPPPGKPQGPPPQGDKSRSPRSP----PGKPQGPPPQGGNQ 168

Query: 201 QRMNPPRGMGPMGPGPQNYGSGMRPPP--NSLGPAMPG----INMGPGAGRPWPNPNSAN 254
            +  PP    P GP PQ       PPP     GP   G     +  P      P P   N
Sbjct: 169 PQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228

Query: 255 SIPYSSSSPGTYVGPPGGGG-------PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSR 307
                   PG   GPP  GG       PPG P  P     + S         P  P    
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE 288

Query: 308 SNFPMGPGSDGPMGG 322
            N P GP    P GG
Sbjct: 289 GNNPQGP--PPPAGG 301



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 74/229 (32%), Positives = 81/229 (35%), Gaps = 35/229 (15%)

Query: 98  PSPVLGNIP---PNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPF--M 152
           P P  GN P   P  G P GP P G     P S P     PPP   +   GP   P    
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180

Query: 153 SPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMD----PTRQQGHPNMGGSMQRMNPPRG 208
            P   GG +P    G  PPG   G  P    S      P + QG P  GG+  +  PP  
Sbjct: 181 GPPPQGGKKP---QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237

Query: 209 MGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVG 268
             P GP PQ       PPP       PG   GP A +      SA S P     P    G
Sbjct: 238 GKPQGPPPQGGNKPQGPPP-------PGKPQGPPA-QGGSKSQSARSPPGKPQGPPQQEG 289

Query: 269 ------PPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP 311
                 PP  GG P  P  P PA              P PP G R + P
Sbjct: 290 NNPQGPPPPAGGNPQQPQAP-PAGQPQGP--------PRPPQGGRPSRP 329



 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 50/151 (33%), Positives = 62/151 (41%), Gaps = 33/151 (21%)

Query: 106 PPNDGM-PGGPIPPGFFQGPPGS-QPSPHAQPPPHNPSSMMGPH----SQPFMSPRYAGG 159
           PP  G  P GP PPG  QGPP     S  +Q PP  P    GP     +QP   P   G 
Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ---GPPPQGGNQPQGPPPPPGK 239

Query: 160 PR-PPIRMGNQPPGGVPGTQPLLPNSMD----------------PTRQQGH------PNM 196
           P+ PP + GN+P G  P  +P  P +                  P +Q+G+      P  
Sbjct: 240 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA 299

Query: 197 GGSMQRMNPPRGMGPMG-PGPQNYGSGMRPP 226
           GG+ Q+   P    P G P P   G   RPP
Sbjct: 300 GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 92/311 (29%), Positives = 106/311 (34%), Gaps = 52/311 (16%)

Query: 96  AAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPR 155
           A P    G  P  DG+PGGP      +G PGS   P +   P  P S             
Sbjct: 515 AGPRGAAGE-PGRDGVPGGP----GMRGMPGSPGGPGSDGKPGPPGSQ-----------G 558

Query: 156 YAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 215
            +G P PP   G   P G PG          P    G P   G       P G GP GP 
Sbjct: 559 ESGRPGPP---GPSGPRGQPGVMGF----PGPKGNDGAPGKNGER---GGPGGPGPQGPP 608

Query: 216 PQNYGSGMRPPPNSLG----------PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT 265
            +N  +G + PP   G          P   G+   PG G P P  N     P      G 
Sbjct: 609 GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGP-PGENGKPGEPGPKGDAGA 667

Query: 266 YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP----------G 315
             G PGG G  G P    P     +         P P GG  +  P GP          G
Sbjct: 668 -PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726

Query: 316 SDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPP---GTPRDDGELGGNF 371
             G  GG+G   P    G  G    DG+P K+ P   +G   PP   G P D GE G   
Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786

Query: 372 LHSFQNDNYSP 382
           L        SP
Sbjct: 787 LPGIAGPRGSP 797



 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 99/333 (29%), Positives = 119/333 (35%), Gaps = 71/333 (21%)

Query: 89  FHDYSAAAAPSPVLGNIPPN----DGMPGGPIPPGF--------FQGPPGSQPSPHAQPP 136
           F +  A     P     PPN     G  G P PPG           G PGS  SP   PP
Sbjct: 81  FGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG--PP 138

Query: 137 PHNPSSMMGPHSQPFMSPRY--------------AGGPRPPIRMGNQPPGGVPGTQ--PL 180
               S   GP +    SP+Y              AG P P    G   P G PGT   P 
Sbjct: 139 GICESCPTGPQNY---SPQYDSYDVKSGVAVGGLAGYPGPA---GPPGPPGPPGTSGHPG 192

Query: 181 LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG-PAMPGINM 239
            P S       G P   G      PP  +GP GP  ++  SG    P   G P  PGI  
Sbjct: 193 SPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIK- 251

Query: 240 GPGAGRPW----------------------PNPNSANSIPYSSSSPGTYVGPPGGGGPPG 277
           GP AG P                       P     N +P  + +PG  +GP G  G  G
Sbjct: 252 GP-AGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGP-MGPRGAPGERG 309

Query: 278 TPIMPSPADSTNSSDNIYTMINPVPPGG-SRSNFPMGPGSDGPMGGMGGMEPHHMNGSLG 336
            P +P  A +  +     +   P PPG    + FP  PG+ G +G  G        GS G
Sbjct: 310 RPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP------GSNG 363

Query: 337 SGDIDGLPKNSPNNISGISNPPGTPRDDGELGG 369
           +    G P   P   +G   PPG P  +G  GG
Sbjct: 364 APGQRGEP--GPQGHAGAQGPPGPPGINGSPGG 394



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 97/302 (32%), Positives = 110/302 (36%), Gaps = 55/302 (18%)

Query: 96  AAPSPVLGNIPPNDGMPGGPIPPGFFQGP--PGSQPSPHAQPP--PHNPSSMMGPHSQPF 151
           AA +P L  +P   G  G P P G    P  PG+   P    P  P  P    GP  QP 
Sbjct: 718 AAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPG 777

Query: 152 M-----SPRYAG--GPR--PPIRMGNQPPG--GVPGT--QPLLPNSMDPTRQQGHPNMGG 198
                 +P   G  GPR  P  R    PPG  G PG   Q   P         G    GG
Sbjct: 778 DKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837

Query: 199 SMQRMNPPRGMGPMG-PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIP 257
                 PP G GP G PGPQ    G R  P   GP   G    PGA R  P P  +N  P
Sbjct: 838 PPGVAGPPGGSGPAGPPGPQGV-KGERGSPG--GPGAAGF---PGA-RGLPGPPGSNGNP 890

Query: 258 YSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG---- 313
                     GPPG  G PG    P PA +T +         P  PG S      G    
Sbjct: 891 ----------GPPGPSGSPGKDGPPGPAGNTGA---------PGSPGVSGPKGDAGQPGE 931

Query: 314 ---PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP----KNSPNNISGISNPPGTPRDDGE 366
              PG+ GP G  G +    + G+ G     G+P       P  + G S  PG     GE
Sbjct: 932 KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991

Query: 367 LG 368
            G
Sbjct: 992 RG 993



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 80/277 (28%), Positives = 96/277 (34%), Gaps = 25/277 (9%)

Query: 103  GNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGG-PR 161
            G  P   G PGG  P G    PPG Q     +  P  P +   P ++    P  + G P 
Sbjct: 836  GGPPGVAGPPGGSGPAG----PPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891

Query: 162  PPIRMGNQPPGGVPGTQ-----PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGP 216
            PP   G+    G PG       P  P    P    G P   GS     PP   GP+G   
Sbjct: 892  PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG 951

Query: 217  QNYGSGMRPPPNSLGP-AMPGINMGPG-AGRPWPNPNSA-NSIPYSSSSPGT--YVGPPG 271
                 G+  PP   GP   PG     G +G+P  N  S     P     PG     G PG
Sbjct: 952  ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011

Query: 272  GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHM 331
              G PG+  +P    S     +     +P  PG      P  PG  GP+G  G       
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA-----PGHPGPPGPVGPAGKSGDRGE 1066

Query: 332  NGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
            +G  G     G     P    G   P G   D GE G
Sbjct: 1067 SGPAGPAGAPG-----PAGSRGAPGPQGPRGDKGETG 1098



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 80/286 (27%), Positives = 94/286 (32%), Gaps = 44/286 (15%)

Query: 106  PPNDGMPGGPIPPGF--------FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMS---- 153
            P   G PG P P G           GPPG  P P   P P       G      +S    
Sbjct: 935  PGAQGPPGAPGPLGIAGITGARGLAGPPG-MPGPRGSPGPQGVKGESGKPGANGLSGERG 993

Query: 154  -------PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPP 206
                   P  AG    P R GN    G+PG     P       + G P   G+     PP
Sbjct: 994  PPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS-PGGKGDRGENGSPGAPGAPGHPGPP 1052

Query: 207  RGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT- 265
               GP+GP  ++   G        GPA P    GP   R  P P         +   G  
Sbjct: 1053 ---GPVGPAGKSGDRG------ESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAA 1103

Query: 266  -YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGM 323
               G  G  G PG P  P PA    +  +      P P G      P GP G DG  G  
Sbjct: 1104 GIKGHRGFPGNPGAPGSPGPAGQQGAIGS------PGPAGPRGPVGPSGPPGKDGTSGHP 1157

Query: 324  GGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGG 369
            G + P    G+ G    +G P +      G   PPG P   G   G
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGH-----PGQPGPPGPPGAPGPCCG 1198



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 77/263 (29%), Positives = 92/263 (34%), Gaps = 40/263 (15%)

Query: 108 NDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMG 167
           +DG PG P PPG   G PGS  +     P  +P S   P  +        G P P    G
Sbjct: 328 SDGQPGPPGPPGT-AGFPGSPGAKGEVGPAGSPGSNGAPGQR--------GEPGPQGHAG 378

Query: 168 NQPPGGVPGTQ--PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRP 225
            Q P G PG    P     M P    G P + G+          GP GP   N   G+R 
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR---------GPPGPAGANGAPGLRG 429

Query: 226 PPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPA 285
                G   PG N   G   P      A  IP    + G   G  G  G PG   +P  A
Sbjct: 430 -----GAGEPGKNGAKGEPGPRGERGEAG-IPGVPGAKGED-GKDGSPGEPGANGLPGAA 482

Query: 286 DSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPK 345
               +         P  P G        PG  GP G  G   P    G+ G    DG+P 
Sbjct: 483 GERGAPG----FRGPAGPNGI-------PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPG 531

Query: 346 NSPNNISGISNPPGTPRDDGELG 368
                + G+   PG P  DG+ G
Sbjct: 532 GP--GMRGMPGSPGGPGSDGKPG 552



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 79/266 (29%), Positives = 91/266 (34%), Gaps = 48/266 (18%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIR 165
           P  +G  G P P G  +G  G    P A+       S   P +     P  AG    P  
Sbjct: 434 PGKNGAKGEPGPRGE-RGEAGIPGVPGAKGEDGKDGSPGEPGANGL--PGAAGERGAPGF 490

Query: 166 MGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRG-MGPMGPGPQNYGSGMR 224
            G   P G+PG +        P  ++G P   G       PRG  G  G      G GMR
Sbjct: 491 RGPAGPNGIPGEK-------GPAGERGAPGPAG-------PRGAAGEPGRDGVPGGPGMR 536

Query: 225 PPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP-IMP 282
                    MPG   GPG+ G+P P        P S    G   GPPG  GP G P +M 
Sbjct: 537 --------GMPGSPGGPGSDGKPGP--------PGSQGESGR-PGPPGPSGPRGQPGVMG 579

Query: 283 SPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG 342
            P    N            P        P GPG  GP G  G   P    G  G G   G
Sbjct: 580 FPGPKGNDG---------APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKG 630

Query: 343 LPKNSPNNISGISNPPGTPRDDGELG 368
                P    G+   PGT    GE G
Sbjct: 631 --DTGPPGPQGLQGLPGTGGPPGENG 654



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 57/191 (29%), Positives = 75/191 (39%), Gaps = 16/191 (8%)

Query: 205 PPRGMGPMGP----GP-----QNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSAN 254
           PP G GP GP    GP     +N   G+   P S G P  PGI      G    +P   +
Sbjct: 98  PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS 157

Query: 255 SIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG- 313
               S  + G   G PG  GPPG P  P  +    S  +      P  PG +  + P G 
Sbjct: 158 YDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP 217

Query: 314 PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLH 373
           PG+ GP G  G       +G  G     GLP   P  I G +  PG P   G  G +  +
Sbjct: 218 PGAIGPSGPAG---KDGESGRPGRPGERGLP--GPPGIKGPAGIPGFPGMKGHRGFDGRN 272

Query: 374 SFQNDNYSPSM 384
             + +  +P +
Sbjct: 273 GEKGETGAPGL 283



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 59/200 (29%), Positives = 72/200 (36%), Gaps = 24/200 (12%)

Query: 94   AAAAPSPVLGNIPPNDGMPGGPIPPG-----FFQGPPGSQPSP-HAQPP-PHNPSSMMGP 146
            A  A  P     P +DG+PG    PG        G PG+  +P H  PP P  P+   G 
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD 1063

Query: 147  HSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPP 206
              +   +   AG P P    G   P G  G +         T ++G   + G       P
Sbjct: 1064 RGESGPAGP-AGAPGPAGSRGAPGPQGPRGDK-------GETGERGAAGIKGHRGFPGNP 1115

Query: 207  RGMGPMGPGPQNYGSGMRPPPNSLGPAMP-------GINMGPGAGRPWPNPNSANSIPYS 259
               G  GP  Q    G   P    GP  P       G +  PG   P P P        S
Sbjct: 1116 GAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP-PGPRGNRGERGS 1174

Query: 260  SSSPGTYVGPPGGGGPPGTP 279
              SPG + G PG  GPPG P
Sbjct: 1175 EGSPG-HPGQPGPPGPPGAP 1193



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 58/195 (29%), Positives = 70/195 (35%), Gaps = 23/195 (11%)

Query: 99   SPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSP-HAQPP-PHNPSSMMGPHSQPFMSPRY 156
            +P    +P  DG PGG    G   G PG+  +P H  PP P  P+   G   +   +   
Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGE-NGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP- 1072

Query: 157  AGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGP 216
            AG P P    G   P G  G +         T ++G   + G       P   G  GP  
Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDK-------GETGERGAAGIKGHRGFPGNPGAPGSPGPAG 1125

Query: 217  QNYGSGMRPPPNSLGPAMP-------GINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 269
            Q    G   P    GP  P       G +  PG   P P P        S  SPG     
Sbjct: 1126 QQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP-PGPRGNRGERGSEGSPGH---- 1180

Query: 270  PGGGGPPGTPIMPSP 284
            PG  GPPG P  P P
Sbjct: 1181 PGQPGPPGPPGAPGP 1195


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 70/216 (32%), Positives = 81/216 (37%), Gaps = 37/216 (17%)

Query: 106 PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR-P 162
           PP  G P GP P G    QGPP     P   PPP   +   GP  +P       G P  P
Sbjct: 114 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGNQSQGPPPRP-------GKPEGP 165

Query: 163 PIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSG 222
           P + GNQ  G  P           P + +G P  GG+  +  PPR   P GP PQ     
Sbjct: 166 PPQGGNQSQGPPP----------HPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 215

Query: 223 MRPPPNSLGPAMPGINMG-------PGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGP 275
             PPP    P  P    G       P  G+P   P    + P     PG   GPP  GG 
Sbjct: 216 QGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGN 275

Query: 276 PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP 311
           P  P +P PA              P PP G R + P
Sbjct: 276 PQQP-LPPPAGKPQGP--------PPPPQGGRPHRP 302



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 89/303 (29%), Positives = 105/303 (34%), Gaps = 56/303 (18%)

Query: 83  SSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSS 142
           SS      D S   +PS + G   P    P G   P     PPG    P  +PP     S
Sbjct: 14  SSAQSLNEDVSQEESPSVISGK--PEGRRPQGGNQPQRTPPPPGK---PEGRPPQGGNQS 68

Query: 143 MMGPHSQPFMSPRYAGGPR-PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQ 201
             GP  +P       G P  PP + GNQ  G  P           P + +G P  GG+  
Sbjct: 69  Q-GPPPRP-------GKPEGPPPQGGNQSQGPPPR----------PGKPEGQPPQGGNQS 110

Query: 202 RMNPPRGMGPMGPGPQNYGSGMRPPP---NSLGPAMPGINMG----PGAGRP-WPNPNSA 253
           +  PPR   P GP PQ       PPP      GP   G N      P  G+P  P P   
Sbjct: 111 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG 170

Query: 254 NSIPYSSSSPGTYVGPP--GGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNF- 310
           N        PG   GPP  GG    G P  P   +             P P GG++S   
Sbjct: 171 NQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPE------------GPPPQGGNQSQGP 218

Query: 311 PMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSP---NNISGISNPPGTPRDDGEL 367
           P  PG        GG +P       G     G P+  P    N      PPG P+     
Sbjct: 219 PPRPGKPEGPPSQGGNKPQ------GPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPP 272

Query: 368 GGN 370
           GGN
Sbjct: 273 GGN 275



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 63/189 (33%), Positives = 73/189 (38%), Gaps = 36/189 (19%)

Query: 98  PSPVLGNI----PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPF 151
           P P  GN     PP  G P GP P G    QGPP     P   PPP   +   GP  +P 
Sbjct: 144 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEG-PPPQGGNQSQGPPPRP- 201

Query: 152 MSPRYAGGPR-PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG 210
                 G P  PP + GNQ  G  P           P + +G P+ GG+  +  PP    
Sbjct: 202 ------GKPEGPPPQGGNQSQGPPPR----------PGKPEGPPSQGGNKPQGPPPHPGK 245

Query: 211 PMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPP 270
           P GP PQ      RPPP       PG   GP    P P  N    +P  +  P     PP
Sbjct: 246 PQGPPPQEGNKPQRPPP-------PGRPQGP----PPPGGNPQQPLPPPAGKPQGPPPPP 294

Query: 271 GGGGPPGTP 279
            GG P   P
Sbjct: 295 QGGRPHRPP 303



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 53/154 (34%), Positives = 61/154 (39%), Gaps = 29/154 (18%)

Query: 98  PSPVLGNI----PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPF 151
           P P  GN     PP+ G P GP P G    QGPP     P   PPP   +   GP  +P 
Sbjct: 165 PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGNQSQGPPPRP- 222

Query: 152 MSPRYAGGPR-PPIRMGNQPPGGVP------------GTQPLLPNSMDPTRQQGHPNMGG 198
                 G P  PP + GN+P G  P            G +P  P    P R QG P  GG
Sbjct: 223 ------GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPP--PGRPQGPPPPGG 274

Query: 199 SMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP 232
           + Q+  PP    P GP P   G     PP    P
Sbjct: 275 NPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 86/280 (30%), Positives = 103/280 (36%), Gaps = 54/280 (19%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
           G PG P P GF QGPPG    P A  P       MGP           G P PP + G+ 
Sbjct: 191 GPPGAPGPQGF-QGPPGEPGEPGASGP-------MGPR----------GPPGPPGKNGDD 232

Query: 170 PPGGVPGTQPLLPNSMDPTRQQGHPNMGGS--MQRMNPPRGM----------GPMGPGPQ 217
              G PG     P    P   QG   + G+  +  M   RG           GP GP  +
Sbjct: 233 GEAGKPGR----PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288

Query: 218 NYGSGMRPPPNSLGP-AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPP 276
               G    P  +GP  +PG    PGA    P P  A     ++ + G   GP G  GPP
Sbjct: 289 PGSPGENGAPGQMGPRGLPGERGRPGA----PGPAGARGNDGATGAAGP-PGPTGPAGPP 343

Query: 277 GTPIM------PSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPH 329
           G P          P     S         P PPG + +  P G PG+DG  G  G     
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGA---- 399

Query: 330 HMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGELG 368
             NG+ G     G P    P+   G   PPG   + GE G
Sbjct: 400 --NGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPG 437



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 94/309 (30%), Positives = 113/309 (36%), Gaps = 54/309 (17%)

Query: 96   AAPSPVLGNI--PPNDGMPGGPIPPGFFQ--------GPPGSQPSPHAQPP----PHNPS 141
            A P   +GN+  P   G  G   PPG           GPPG  PS +A PP    P    
Sbjct: 847  AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG--PSGNAGPPGPPGPAGKE 904

Query: 142  SMMGPHSQ--PFMSPRYAGGPRPPIRMGNQP------PGGVPGTQPLLPNSMDPTRQQGH 193
               GP  +  P   P   G P PP   G +       P G PGT    P       Q+G 
Sbjct: 905  GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGT----PGPQGIAGQRGV 960

Query: 194  PNMGGSMQRMNPPRGMGPMG-PGPQ--NYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNP 250
              + G       P   GP G PG Q  +  SG R PP  +GP  PG+   PG       P
Sbjct: 961  VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP--PGLAGPPGESGREGAP 1018

Query: 251  NSANSIPYSSSSPGTY--------VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 302
             +  S P    SPG           GPPG  G PG P    PA  +           P  
Sbjct: 1019 GAEGS-PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGET----GPAG 1073

Query: 303  PGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTP 361
            P G     P+GP G+ GP G  G        G  G   I G      + + G   PPG+P
Sbjct: 1074 PAG-----PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKG--HRGFSGLQGPPGPPGSP 1126

Query: 362  RDDGELGGN 370
             + G  G +
Sbjct: 1127 GEQGPSGAS 1135



 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 90/295 (30%), Positives = 104/295 (35%), Gaps = 45/295 (15%)

Query: 93   SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGS--QPSPHAQPPPHNPSSMMGPHSQP 150
            S  A P+   G  P + G PG P P GF  GPPG+  QP    +P         GP    
Sbjct: 787  SGPAGPTGARG-APGDRGEPGPPGPAGF-AGPPGADGQPGAKGEPGDAGAKGDAGP---- 840

Query: 151  FMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG 210
               P  AG   PP  +GN    G  G +     S  P    G P   G +    P    G
Sbjct: 841  ---PGPAGPAGPPGPIGNVGAPGAKGAR----GSAGPPGATGFPGAAGRVGPPGPSGNAG 893

Query: 211  PMG-PGPQNYGSGMRP--------------PPNSLGPAMPGINMGPGAGRPWPNPNSANS 255
            P G PGP     G  P              PP   GPA  G    PGA  P   P +   
Sbjct: 894  PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA--GEKGSPGADGPAGAPGTPG- 950

Query: 256  IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-P 314
             P   +     VG PG  G  G P +P P+                PPG      PMG P
Sbjct: 951  -PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG------PMGPP 1003

Query: 315  GSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGELG 368
            G  GP G  G        G+ GS   DG P        +G + PPG P   G  G
Sbjct: 1004 GLAGPPGESG---REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG 1055



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 87/289 (30%), Positives = 100/289 (34%), Gaps = 47/289 (16%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMG----PHSQPFMSPRYAGGPR 161
           P   G+PG   PPG   G PG Q  P     P  PS   G    P  +    P    GPR
Sbjct: 640 PGFQGLPGPAGPPGE-AGKPGEQGVPGDLGAP-GPSGARGERGFPGERGVQGPPGPAGPR 697

Query: 162 ----PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP--- 214
                P   G +   G PG     P S      QG P   G+     P    G  GP   
Sbjct: 698 GANGAPGNDGAKGDAGAPGA----PGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753

Query: 215 --GPQNYG-SGMRPPPNSLGPA-MPGINMGPGAGRPWPNPNSANSIPYSSSSPGT----- 265
              P   G  G+  P    GPA  PG     G   P   P  A   P     PG      
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGP-AGPTGARGAPGDRGEPGPPGPAG 812

Query: 266 YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMGGMG 324
           + GPPG  G PG    P  A +   +          PPG      P GP G  GP+G +G
Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAG---------PPG------PAGPAGPPGPIGNVG 857

Query: 325 GMEPHHMNGSLGSGDIDGLP----KNSPNNISGISNPPGTPRDDGELGG 369
                   GS G     G P    +  P   SG + PPG P   G+ GG
Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 89/300 (29%), Positives = 105/300 (35%), Gaps = 54/300 (18%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQPFMSPRY- 156
           P  D  P GP  P    GPPG          P P   P P  P   +G +  P +S  Y 
Sbjct: 113 PKGDTGPRGPRGPA---GPPGRDGIPGQPGLPGPPGPPGPPGPPG-LGGNFAPQLSYGYD 168

Query: 157 ---AGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG 213
               GG   P  MG   P G+PG     P +  P   QG P   G      P    GP G
Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGP----PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG 224

Query: 214 PGPQNYGS---------GMRPPPNSLGP-AMPGINMGPG-------------AGRPWP-N 249
           P  +N            G R PP   G   +PG    PG              G   P  
Sbjct: 225 PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG 284

Query: 250 PNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSN 309
           P      P  + +PG  +GP G  G  G P  P PA     +D       P  P G    
Sbjct: 285 PKGEPGSPGENGAPG-QMGPRGLPGERGRPGAPGPA-GARGNDGATGAAGPPGPTG---- 338

Query: 310 FPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
            P G PG  G +G  G   P    GS G   + G P   P   +G + P G P  DG+ G
Sbjct: 339 -PAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEP--GPPGPAGAAGPAGNPGADGQPG 395



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 87/325 (26%), Positives = 113/325 (34%), Gaps = 59/325 (18%)

Query: 91  DYSAAAAPSPVLGNIPPND-------GMPGGPIPPGFFQGPPGSQPSPHAQ--PPPHNPS 141
           D  A   P PV    PP         G  G P P G   GPPG +  P ++  P     +
Sbjct: 444 DTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL-PGPPGERGGPGSRGFPGADGVA 502

Query: 142 SMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLL--PNSMDPTRQQGHPNMGGS 199
              GP  +   SP  AG    P   G     G+PG + L   P S  P  + G P   G 
Sbjct: 503 GPKGPAGERG-SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQ 561

Query: 200 MQRMNPP-----------------------------RGM----GPMGPGPQNYGSGMRPP 226
             R  PP                             RG+    G +GP  ++  +G + P
Sbjct: 562 DGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGP 621

Query: 227 PNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPAD 286
           P   GPA      GP AG P         +P  +  PG   G PG  G PG    P P+ 
Sbjct: 622 PGPAGPAGERGEQGP-AGSP-----GFQGLPGPAGPPGE-AGKPGEQGVPGDLGAPGPSG 674

Query: 287 STNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPK 345
           +              PPG +      G PG+DG  G  G        GS G+  + G+P 
Sbjct: 675 ARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA---PGAPGSQGAPGLQGMP- 730

Query: 346 NSPNNISGISNPPGTPRDDGELGGN 370
                 +G+  P G   D G  G +
Sbjct: 731 -GERGAAGLPGPKGDRGDAGPKGAD 754



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 61/188 (32%), Positives = 75/188 (39%), Gaps = 28/188 (14%)

Query: 106  PPNDGMPGGPIPPGFF--QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPP 163
            P  DG PG     G     GPPG+  +P A P P  P+   G   +    P    GP  P
Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGA-PGPVGPAGKSGDRGET--GPAGPAGPVGP 1080

Query: 164  IRMGNQPPGGVPGTQPLLPNSMDPTRQQG------HPNMGGSMQRMNPPRGMGPMGPGPQ 217
            +  G + P G  G +         T +QG      H    G      PP   G  GP   
Sbjct: 1081 V--GARGPAGPQGPR----GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134

Query: 218  NYGSGMRPPPNSLG-PAMPGINMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGP 275
            +  +G R PP S G P   G+N  PG  G P P   + ++ P         VGPPG  GP
Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGP---------VGPPGPPGP 1185

Query: 276  PGTPIMPS 283
            PG P  PS
Sbjct: 1186 PGPPGPPS 1193



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 85/302 (28%), Positives = 101/302 (33%), Gaps = 68/302 (22%)

Query: 109 DGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGN 168
           D  P GP      +G PGS P  +  P    P  + G   +P       G P P    GN
Sbjct: 279 DAGPAGP------KGEPGS-PGENGAPGQMGPRGLPGERGRP-------GAPGPAGARGN 324

Query: 169 QPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGSGMRPPP 227
               G  G     P    P    G P   G+     P    GP G  GPQ    G+R  P
Sbjct: 325 DGATGAAGP----PGPTGPAGPPGFPGAVGAKGEAGP---QGPRGSEGPQ----GVRGEP 373

Query: 228 NSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPG-----TYVGPPGGGGPP------ 276
              GPA      G       P    AN  P  + +PG        GP G GGPP      
Sbjct: 374 GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433

Query: 277 GTPIMPSPADSTNSSDNIYTMINPVPPG--------GSR-----SNFP------MGPGSD 317
           G P  P     T +      +    PPG        G+R     +  P       GPGS 
Sbjct: 434 GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSR 493

Query: 318 GPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPN-----------NISGISNPPGTPRDDGE 366
           G  G  G   P    G  GS    G PK SP               G++  PG+P  DG+
Sbjct: 494 GFPGADGVAGPKGPAGERGSPGPAG-PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552

Query: 367 LG 368
            G
Sbjct: 553 TG 554



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 64/233 (27%), Positives = 76/233 (32%), Gaps = 31/233 (13%)

Query: 105  IPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRP 162
            +P   G PG  GP      +GPPG    P    PP        P ++   SP   G P  
Sbjct: 975  LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEG--SPGRDGSPGA 1032

Query: 163  PIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSG 222
                G   P G PG  P  P +  P    G     G      P    GP+GP      +G
Sbjct: 1033 KGDRGETGPAGPPGA-PGAPGAPGPV---GPAGKSGDRGETGPAGPAGPVGPVGARGPAG 1088

Query: 223  MRPPPNSLGPAMP----GINMGPG----AGRPWPNPNSANSIPYSSSSPGTYVGPPGGG- 273
             + P    G        GI    G     G P P  +     P  +S P    GPPG   
Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG 1148

Query: 274  --------GPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDG 318
                    G PG    P P   T  +  +     P PPG      P GP S G
Sbjct: 1149 APGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG------PPGPPSAG 1195



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 76/274 (27%), Positives = 98/274 (35%), Gaps = 71/274 (25%)

Query: 125 PGSQPSPHAQPPPHNPSSMMGPHSQPFMS---PRYAGGPRPPIRMGNQPPG--GVPGTQP 179
           PG++  P  +  P  P     P  Q       P+   GPR P R    PPG  G+PG QP
Sbjct: 82  PGAEV-PEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGP-RGPAGPPGRDGIPG-QP 138

Query: 180 LLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQ-NYGSGMRPPPNSLGPAMPGIN 238
            LP    P    G P +GG+                PQ +YG   +   ++ G ++PG  
Sbjct: 139 GLPGPPGPPGPPGPPGLGGNF--------------APQLSYGYDEK---STGGISVPG-P 180

Query: 239 MGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMI 298
           MGP   R  P                   GPPG  GP G    P       +S  +    
Sbjct: 181 MGPSGPRGLP-------------------GPPGAPGPQGFQGPPGEPGEPGASGPMGPRG 221

Query: 299 NPVPPG----GSRSNFPMGPGSDGPMG-----------GMGGMEPHH----MNGSLGSGD 339
            P PPG       +  P  PG  GP G           G+ GM+ H     ++G+ G   
Sbjct: 222 PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281

Query: 340 IDGLPKNSP-----NNISGISNPPGTPRDDGELG 368
             G PK  P     N   G   P G P + G  G
Sbjct: 282 PAG-PKGEPGSPGENGAPGQMGPRGLPGERGRPG 314



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/110 (31%), Positives = 39/110 (35%), Gaps = 26/110 (23%)

Query: 122  QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPG--GVPGTQP 179
            QGPPG   SP  Q     PS   GP            GPR P       PG  G PG   
Sbjct: 1117 QGPPGPPGSPGEQ----GPSGASGP-----------AGPRGP-------PGSAGAPGKDG 1154

Query: 180  L--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 227
            L  LP  + P   +G     G +    PP   GP GP    +     P P
Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQP 1204


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 97/309 (31%), Positives = 110/309 (35%), Gaps = 54/309 (17%)

Query: 99  SPVLGNIP-PNDGMPGGPIPPGFFQGPPGSQ----------PSPHAQPPPHNPSSMMGPH 147
           +P+LG  P P  G P   IP GF Q  P  Q          P P  Q  P  P   MGP 
Sbjct: 580 TPLLGPQPFPGQG-PMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQ 638

Query: 148 SQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPR 207
             P     + GG  P   MG Q P G P   P   +   P   Q HP   G +    PP 
Sbjct: 639 GPPL----HQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPG 694

Query: 208 GMGPMG----------PGPQNYGSGMRP--PPNSLGPAMP----GINMGPG----AGRPW 247
             G  G          PGPQ +     P  P   LGP  P    G+   PG     G P 
Sbjct: 695 PQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPH 754

Query: 248 PN-----PNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPA-DSTNSSDNIYTMINPV 301
           P+     P S       S  P   + P G  GPPG      PA            M  P 
Sbjct: 755 PHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPH 814

Query: 302 PPGGSRSNFPM---GP----GSDG--PMGGMGGMEPHHMNGSLGSGDIDGLPKNS--PNN 350
           PPGG   + P    GP    G  G  P G M G  P  + G  GS    G P+ S  P  
Sbjct: 815 PPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLG-PPQELRGPPGSQSQQGPPQGSLGPPP 873

Query: 351 ISGISNPPG 359
             G+  PPG
Sbjct: 874 QGGMQGPPG 882



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 77/245 (31%), Positives = 93/245 (37%), Gaps = 35/245 (14%)

Query: 134 QPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGH 193
           QPPP + + ++GP  QPF       GP   I  G Q P   P  Q  +P +M    Q G 
Sbjct: 573 QPPPSSGTPLLGP--QPFPGQ----GPMSQIPQGFQQPH--PSQQ--MPMNM---AQMGP 619

Query: 194 PNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSA 253
           P   G  +   P   MGP GP P + G G   P   +GP  P    GP  G   P P   
Sbjct: 620 PGPQGQFRPPGPQGQMGPQGP-PLHQGGG--GPQGFMGPQGP---QGPPQG--LPRPQDM 671

Query: 254 NSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPAD--STNSSDNIYTMINPVPPGGSRSNF- 310
           +        PG + GP G  GPPG      P               I P  P G + +  
Sbjct: 672 HGPQGMQRHPGPH-GPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730

Query: 311 PMGP-------GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSP---NNISGISNPPGT 360
           P GP       G  GP G  G   PH + G  GS  I G     P    N  G+  PPG 
Sbjct: 731 PQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGP 790

Query: 361 PRDDG 365
             + G
Sbjct: 791 RENQG 795



 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 77/245 (31%), Positives = 87/245 (35%), Gaps = 40/245 (16%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQ--PSPHAQPPPH--NPSSMMGPHSQPFMSPRYAGGP- 160
           P   GM G P P G  QG PGSQ    P +Q P    NP  M GP       PR   GP 
Sbjct: 744 PGPRGMQGPPHPHGI-QGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG-----PRENQGPA 797

Query: 161 -------RPPIRM-GNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPM 212
                   PP  M G  PPGG+ G  P         R    P   GSM  + PP+ +   
Sbjct: 798 PQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSM--LGPPQELR-- 853

Query: 213 GPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNP-----NSANSIPY-SSSSPGTY 266
             GP    S   PP  SLGP   G   GP   +   NP      S   IP+    +P   
Sbjct: 854 --GPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLG 911

Query: 267 VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGM 326
            GP       G    P P             I P+ PG        GPG +   G   G 
Sbjct: 912 DGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPG-------QGPGPN--KGDSRGP 962

Query: 327 EPHHM 331
             HHM
Sbjct: 963 PNHHM 967



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 41/128 (32%), Positives = 49/128 (38%), Gaps = 23/128 (17%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGP-HSQPFMSPRYAGGPRPPI 164
           PP   +  GP P G  QGPPG Q     Q P   P    GP   Q   +P    GPR P 
Sbjct: 864 PPQGSL--GPPPQGGMQGPPGPQGQ---QNPARGPHPSQGPIPFQQQKTPLLGDGPRAPF 918

Query: 165 RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMR 224
               Q      G  PL+P         G     G +  +NP +G GP      N G    
Sbjct: 919 NQEGQS----TGPPPLIPG-------LGQQGAQGRIPPLNPGQGPGP------NKGDSRG 961

Query: 225 PPPNSLGP 232
           PP + +GP
Sbjct: 962 PPNHHMGP 969



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 65/272 (23%), Positives = 92/272 (33%), Gaps = 56/272 (20%)

Query: 89   FHDYSAAAAPSPVL---------GNIPP-NDGMPGGPI------PPGFFQGPPGSQPSPH 132
            F+    +  P P++         G IPP N G   GP       PP    GP   +    
Sbjct: 918  FNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQ 977

Query: 133  AQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQG 192
            +  P H      GP   PF   +   G  PP R G  P      ++   P+   P ++ G
Sbjct: 978  SGGPEH------GPERGPFRGGQDCRG--PPDRRGPHPDFPDDFSR---PDDFHPDKRFG 1026

Query: 193  H-----PNMGGSMQRMNPPRGMGPMGPGPQNY-----GSG---MRPPPNSLGPAMPGINM 239
            H        GG + +    R  GP  P P ++     G G    R PP +     PG   
Sbjct: 1027 HRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDER 1086

Query: 240  GPGAGRPWPNPNSANSIPYSSSSPGTYVG---PPGGGGPPGTPIMPSPADSTNSSDNIYT 296
             P      P         +   +P  + G   P G  G PG P    P ++ ++S+    
Sbjct: 1087 FPRDPED-PRFRGRREESFRRGAPPRHEGRAPPRGRDGFPG-PEDFGPEENFDASEE--- 1141

Query: 297  MINPVPPGGSRSNFPMGPGSDGPMGGMGGMEP 328
                     +R     G G   P GG  G+ P
Sbjct: 1142 --------AARGRDLRGRGRGTPRGGRKGLLP 1165



 Score = 37.4 bits (85), Expect = 0.023
 Identities = 50/170 (29%), Positives = 67/170 (39%), Gaps = 26/170 (15%)

Query: 154  PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMG---GSMQRMNPPRGMG 210
            PR+ GG +P    GN+ PG  PG +    +  D  R    P+ G    S +R +  +GM 
Sbjct: 1171 PRFEGGRKPDSWDGNREPG--PGHE----HFRDTPRPDHPPHDGHSPASRERSSSLQGMD 1224

Query: 211  ----PMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT- 265
                P    P + G G         P  P  + G G GR  P P  A  +P S  S    
Sbjct: 1225 MASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRG-GKGRGGPGP--AQRVPKSGRSSSLD 1281

Query: 266  ------YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPP--GGSR 307
                  Y      GGPPG+   PS    + S+    + +N  PP  G SR
Sbjct: 1282 GEHHDGYHRDEPFGGPPGSG-TPSRGGRSGSNWGRGSNMNSGPPRRGASR 1330


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 87/309 (28%), Positives = 105/309 (33%), Gaps = 37/309 (11%)

Query: 100  PVLGNIPPNDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGP-----HSQPFM 152
            P L   P + G+PG  G +     +GPPG  P P   P    P+   GP        P  
Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGP-PGPAGSPGERGPAGAAGPIGIPGRPGPQG 1111

Query: 153  SPRYAGGPRPPIRMGNQPPGGVPGTQ-PL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMG 210
             P  AG    P   G Q P G  G Q P+ LP    P    G P   G    +  P   G
Sbjct: 1112 PPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPV---GPPGEDGDKGEIGEPGQKG 1168

Query: 211  PMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPP 270
              G        G + PP   GP  P    GP      P P     +       G   G P
Sbjct: 1169 SKGD------KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPR-GFP 1221

Query: 271  GGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGG-SRSNFPMGPGSDGPMGGMGGMEPH 329
            G  GP G   +P P      + ++  M  P PPG    S  P   G  GP GG+G     
Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281

Query: 330  HMNGSLGSGDIDGLP----------------KNSPNNISGISNPPGTPRDDGELGGNFLH 373
               G  G     GLP                ++ P+  +G   P G P DDG  G     
Sbjct: 1282 GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341

Query: 374  SFQNDNYSP 382
             F  D   P
Sbjct: 1342 GFPGDPGPP 1350



 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 88/288 (30%), Positives = 105/288 (36%), Gaps = 39/288 (13%)

Query: 110  GMPG--GPIPPGFFQGPPG-SQPSPHAQPP-PHNPSSMMGPHSQPFMSPRYAGGPRPPIR 165
            G+PG  GP  P   +G  G S PS  A PP P  P    GP   P     + G P PP  
Sbjct: 1294 GLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG-PVGFPGDPGPPGE 1352

Query: 166  MGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYG 220
             G     G PG      +P    S  PT   G P   G   +  PP   GP G   +   
Sbjct: 1353 PGPAGQDGPPGDKGDDGEPGQTGSPGPT---GEPGPSGPPGKRGPPGPAGPEGRQGEKGA 1409

Query: 221  ---SGMRPPPNSLGP----AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGG 273
               +G+  PP   GP      PG   GP   R  P P     +P    SPG   GPPG  
Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGAPG-KPGPDGLRGIPGPVGEQGLP---GSPGP-DGPPGPM 1464

Query: 274  GPPGTPIM--PSPADSTNSSDNIYTMINPVPPGGSRSN--FPMGPGSDGPMGGMGGMEPH 329
            GPPG P +   S          +  +I P    G + +   P   GS GP G  G   P 
Sbjct: 1465 GPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPS 1524

Query: 330  HMNGSLGSGDIDGLP----------KNSPNNISGISNPPGTPRDDGEL 367
               G  G   + G P             P   +G   PPG P   GE+
Sbjct: 1525 GPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV 1572



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 91/312 (29%), Positives = 110/312 (35%), Gaps = 62/312 (19%)

Query: 109  DGMPG--GPIPPGFFQGPPGSQPSPHAQ--PPPHN---PSSMMGPHSQPFMS-------- 153
            DG PG  G + P    GPPG Q +P AQ  P P     P    GP  +P +         
Sbjct: 702  DGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGP 761

Query: 154  PRYAGGPRPPIRMGNQ-PPG-----GVPGTQPL--------LPNSMDPTRQQGHPNMGGS 199
            P + G   PP   G Q PPG     G PG + +        L  +     + G P   G 
Sbjct: 762  PGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGD 821

Query: 200  MQ------RMNPPRGMGPMGP-GPQNYGS-----GMRPPPNSLG----PAMPGI--NMGP 241
            M        + PP   G  GP GP+  G      G   PP   G    P +PG     GP
Sbjct: 822  MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP 881

Query: 242  GAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPV 301
                 +P    AN       +PG   GP G  GP G      P   T           P 
Sbjct: 882  KGSIGFPGFPGANGEKGGRGTPGK-PGPRGQRGPTGPRGERGPRGITG---------KPG 931

Query: 302  PPGGSRSNFPMGP----GSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISN 356
            P G S  + P GP    G +GP G  G   P    G  G   + G P +       G + 
Sbjct: 932  PKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991

Query: 357  PPGTPRDDGELG 368
            PPG P   G  G
Sbjct: 992  PPGPPGVVGPQG 1003



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 81/307 (26%), Positives = 101/307 (32%), Gaps = 80/307 (26%)

Query: 122  QGPPG--SQPSPHAQPPPHNPSSMMGPHSQPFM-------SPRYAGGPRPPIRMGNQPPG 172
            QGPPG      P  QP P       GP  Q  +        PR  G P PP  +G Q   
Sbjct: 1176 QGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPR--GFPGPPGPVGLQ--- 1230

Query: 173  GVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG- 231
            G+PG          P  ++G     G + +M PP   GP GP       G + PP  +G 
Sbjct: 1231 GLPG----------PPGEKGET---GDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277

Query: 232  ---------------PAMPGINMGPG----------------AGRPWPNPNSANSIPYSS 260
                           P +PG    PG                AG P P     +  P  S
Sbjct: 1278 PGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGS 1337

Query: 261  SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 320
              P  + G PG  G PG      P              +P P G    + P  PG  GP 
Sbjct: 1338 PGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP--PGKRGPP 1395

Query: 321  GGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISNP------PGTP 361
            G  G        G+ G   ++G P             K  P+ + GI  P      PG+P
Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP 1455

Query: 362  RDDGELG 368
              DG  G
Sbjct: 1456 GPDGPPG 1462



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 64/194 (32%), Positives = 81/194 (41%), Gaps = 30/194 (15%)

Query: 109  DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRM 166
            +G PG  GPI P   QG PG       +P P     + GP  +  + P   G   PP  M
Sbjct: 1416 EGPPGKTGPIGP---QGAPG-------KPGPDGLRGIPGPVGEQGL-PGSPGPDGPPGPM 1464

Query: 167  GNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSG 222
            G   P G+PG    L     P  ++GHP + G +    PP   G  G    PGPQ   SG
Sbjct: 1465 G---PPGLPG----LKGDSGPKGEKGHPGLIGLI---GPPGEQGEKGDRGLPGPQG-SSG 1513

Query: 223  MRPPPNSLGPAMPGINMGPGA--GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPI 280
             +      GP+ P    GP    G P P     +S P        + GPPG  GPPG  I
Sbjct: 1514 PKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVI 1573

Query: 281  MPSPADSTNSSDNI 294
             P P  ++ +  NI
Sbjct: 1574 QPLPIQASRTRRNI 1587



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 76/267 (28%), Positives = 93/267 (34%), Gaps = 55/267 (20%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIR 165
            PP +  P GP  P  F GP G    P     P +P    G   +     +  G P PP  
Sbjct: 944  PPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHP----GQRGETGFQGK-TGPPGPPGV 998

Query: 166  MGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGS 221
            +G Q P G  G          P  ++GHP   G       P   G  G    PGP     
Sbjct: 999  VGPQGPTGETG----------PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGL-- 1046

Query: 222  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 281
                 P   GP  PG+   PG  R  P P  A  +  +        GPPG  GP G+P  
Sbjct: 1047 -----PGKDGP--PGLRGFPG-DRGLPGPVGALGLKGNE-------GPPGPPGPAGSPGE 1091

Query: 282  PSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDID 341
              PA +            P+         P  PG  GP G  G        G  G    D
Sbjct: 1092 RGPAGAA----------GPI-------GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134

Query: 342  GLPKNSPNNISGISNPPGTPRDDGELG 368
            GL    P  + G + P G P +DG+ G
Sbjct: 1135 GL--QGPVGLPGPAGPVGPPGEDGDKG 1159



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 84/291 (28%), Positives = 102/291 (35%), Gaps = 58/291 (19%)

Query: 110 GMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMG 167
           G PG   PPG    +G PG          P  P  + GP       P  AG P    R G
Sbjct: 568 GRPGPVGPPGSGGLKGEPGDVG-------PQGPRGVQGP-------PGPAGKPGRRGRAG 613

Query: 168 NQPPGGVPG-TQPLLPNSMDPTR----QQGHPNMGGSMQRMNPP-----RG----MGPMG 213
           +    G+PG T P      D       ++GH    G      PP     RG    +GP G
Sbjct: 614 SDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRG 673

Query: 214 ----PGPQNYGSGMRPPPNSLGPAMPGI-----------NMGPGAGRPWPNPNSANSIPY 258
               PGP+    G + PP   GP  PG+           N+GP  G P P     N    
Sbjct: 674 LPGEPGPRGL-LGPKGPPGPPGP--PGVTGMDGQPGPKGNVGP-QGEPGPPGQQGNPGAQ 729

Query: 259 SSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSD 317
               P   +GPPG  GP G P +P    +     +      P   GG     P GP G  
Sbjct: 730 GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789

Query: 318 GPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           GP G  G      + G+ G    DG P        G     G   D GE+G
Sbjct: 790 GPRGVKGADGIRGLKGTKGEKGEDGFP--------GFKGDMGIKGDRGEIG 832



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 86/331 (25%), Positives = 109/331 (32%), Gaps = 73/331 (22%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGFF-----------QGPPGSQPSPHAQPPPHNPSS 142
           A   P  ++   P  +G  G P PPG             +GPPG    P A   P  P +
Sbjct: 459 AIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGT 518

Query: 143 MM---------------GPHSQPFMSPRYA---------GGPRPPIRMGNQP-PGGVPGT 177
           M+               GP      S   A          GP  P+ +  +P P G PG+
Sbjct: 519 MLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGS 578

Query: 178 QPLLPNSMD-----PTRQQGHPNMGGSMQR-----MNPPRGM-GPMGP-GPQNYG----- 220
             L     D     P   QG P   G   R      +  RGM G  GP G + +      
Sbjct: 579 GGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGL 638

Query: 221 ---SGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPG 277
               G R  P   GP  P  + G         P      P     P   +GP G  GPPG
Sbjct: 639 PGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP----GPRGLLGPKGPPGPPG 694

Query: 278 TPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGS 337
            P +           N+     P PPG   +     PG+ G  G  G + P    G LG 
Sbjct: 695 PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGN-----PGAQGLPGPQGAIGPPGEKGPLGK 749

Query: 338 GDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             + G+P        G   PPG P  +G  G
Sbjct: 750 PGLPGMP--------GADGPPGHPGKEGPPG 772



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 77/268 (28%), Positives = 89/268 (33%), Gaps = 49/268 (18%)

Query: 123  GPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLP 182
            GPPG    P  +  P  P    GP+  P        GP  P   G +   GVPG  P  P
Sbjct: 832  GPPG----PRGEDGPEGPKGRGGPNGDP--------GPLGP--PGEKGKLGVPGL-PGYP 876

Query: 183  NSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPPPNSLGPAMP-GINMG 240
                P    G P   G+        G G  G PGP+    G R P    G   P GI   
Sbjct: 877  GRQGPKGSIGFPGFPGANGEKG---GRGTPGKPGPR----GQRGPTGPRGERGPRGIT-- 927

Query: 241  PGAGRPWPNPNSANS---------IPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSS 291
               G+P P  NS             P     P  + GP G  GPPG   +P        +
Sbjct: 928  ---GKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984

Query: 292  DNIYTMINPVPPGGSRSNFPMG----------PGSDGPMGGMGGMEPHHMNGSLGSGDID 341
                    P PPG      P G          PG  GP G  G        G+ G     
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044

Query: 342  GLP-KNSPNNISGISNPPGTPRDDGELG 368
            GLP K+ P  + G     G P   G LG
Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALG 1072



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 54/194 (27%), Positives = 66/194 (34%), Gaps = 34/194 (17%)

Query: 204 NPPRGMGPMGPG-PQNYGS---GMRPPPNSLGPAMPGINMGPGA---GRPWPNPNSANSI 256
           +P      +GPG P N  +   G+  P    G       + PG    G P P   +    
Sbjct: 422 DPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG 481

Query: 257 PYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-- 314
           P  +  P   VG PG  GPPG P +P  AD          M+ P   GG       GP  
Sbjct: 482 PPGTMGPTGQVGDPGERGPPGRPGLPG-ADGLPGPPGTMLML-PFRFGGGGDAGSKGPMV 539

Query: 315 -------------------GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKN-SPNNISGI 354
                              G  GPMG  G   P    G  GSG + G P +  P    G+
Sbjct: 540 SAQESQAQAILQQARLALRGPAGPMGLTGRPGP---VGPPGSGGLKGEPGDVGPQGPRGV 596

Query: 355 SNPPGTPRDDGELG 368
             PPG     G  G
Sbjct: 597 QGPPGPAGKPGRRG 610


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 84/311 (27%), Positives = 110/311 (35%), Gaps = 50/311 (16%)

Query: 98   PSPVLGNI-PPND-GMPGGPIPPGFFQGPPG--------------SQPSPHAQPPPHNPS 141
            P   +GN+ PP + G PG    PG  QG PG               QP     P P  P+
Sbjct: 1113 PPGGVGNLGPPGEKGEPGESGSPGI-QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171

Query: 142  SMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNM 196
               GP   P     + G P PP   G +   G  G      +P  P S  PT + G P  
Sbjct: 1172 GDDGPKGNPG-PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1230

Query: 197  GGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSI 256
             G       P   G  G      G G +  P ++G       +GP      P P+    +
Sbjct: 1231 LGKRGPAGSPGSEGRQG------GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1284

Query: 257  PYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDN--IYTMINPVPPGGSRSN 309
            P S    G        GPPG  GPPG P +   A +     +  +  +I P    G + +
Sbjct: 1285 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1344

Query: 310  FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISN 356
              + PG  G  G  G M     +G +G G   GLP                P    G+  
Sbjct: 1345 RGL-PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1403

Query: 357  PPGTPRDDGEL 367
            PPG P   GE+
Sbjct: 1404 PPGHPGPPGEV 1414



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 86/303 (28%), Positives = 107/303 (35%), Gaps = 65/303 (21%)

Query: 109 DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRM 166
           DG PG  G I     +G  G  P    +  P  P    GP           G P PP  M
Sbjct: 655 DGFPGFKGDIGVKGDRGEVGV-PGSRGEDGPEGPKGRTGP----------TGDPGPPGLM 703

Query: 167 GNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGS--------MQRMNPPRG-MGPMGP--- 214
           G +   GVPG  P  P    P    G P   G+        +   + PRG  GP GP   
Sbjct: 704 GEKGKLGVPGL-PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ 762

Query: 215 -GPQ-----------NYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSS 261
            GP+           + G G   PP   G P   G N  PG   P P P   + +P    
Sbjct: 763 RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-PGPPGKDGLPGHPG 821

Query: 262 SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--------------GSR 307
             G  VG  G  GPPG P +  P  +   +  +    +P PPG              G++
Sbjct: 822 QRGE-VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 880

Query: 308 SN--FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
            +   P  PG DGP G  G      + G+ G   + G          G S PPG     G
Sbjct: 881 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG--------NEGPSGPPGPAGSPG 932

Query: 366 ELG 368
           E G
Sbjct: 933 ERG 935



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 78/279 (27%), Positives = 90/279 (32%), Gaps = 32/279 (11%)

Query: 110  GMPGGPIPPGFFQ--------GPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR 161
            G+PG   PPG           G PG Q         H P    GP   P   P  AG   
Sbjct: 983  GLPGPAGPPGVAGEDGDKGEVGDPG-QKGTKGNKGEHGPPGPPGPIG-PVGQPGAAGADG 1040

Query: 162  PPIRMGNQPPGGVPGTQPL--LPNSMDPTRQQGHPNMGGSMQR------MNPPRGMGPMG 213
             P   G Q   G  G +          P   QG P   G          M PP   GP G
Sbjct: 1041 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1100

Query: 214  PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS--SSPGTYVGPPG 271
            P   N   G + PP  +G      N+GP   +  P  + +  I        P    G  G
Sbjct: 1101 PAGPNGADGPQGPPGGVG------NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154

Query: 272  GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHM 331
              G PG P  P P   T          NP P G      P  PG  GP G  G       
Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDG---PKGNPGPVGFPGD--PGPPGEGGPRGQDGAKGDRGE 1209

Query: 332  NGSLGS-GDIDGLPKNSPNNISGISNPPGTPRDDGELGG 369
            +G  G  G      +N P    G   P G+P  +G  GG
Sbjct: 1210 DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG 1248



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 78/287 (27%), Positives = 97/287 (33%), Gaps = 53/287 (18%)

Query: 122 QGPPG-----SQPSPHAQPP---------------PHNPSSMMGPHSQPFMSPRYA---- 157
           +GPPG      +P P  QP                P  P  + GP  +     R      
Sbjct: 400 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459

Query: 158 -GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-- 214
            G P  P   G++   G+PG    LP       ++GH    G+     PP   G  G   
Sbjct: 460 RGMPGDPGVKGDRGFDGLPG----LPG------EKGHRGDTGAQGLPGPPGEDGERGDDG 509

Query: 215 --GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272
             GP+    G   P   LGP  P    GP   R    P      P  S  P    GPPG 
Sbjct: 510 EIGPRGL-PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG----PKGSLGPQGEPGPPGQ 564

Query: 273 GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHM 331
            G PGT  +P P  +            P  PG   S+ P G PG +GP G  G   P   
Sbjct: 565 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 624

Query: 332 NGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQND 378
            G LG           P  + G+    G     GE G +    F+ D
Sbjct: 625 QGPLG--------YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGD 663



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 80/280 (28%), Positives = 103/280 (36%), Gaps = 51/280 (18%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSM--------MGPHSQP-FMSPR 155
            PP + G+PG P  P  F GP G    P     P +P            GP   P  + P+
Sbjct: 786  PPGERGLPG-PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844

Query: 156  YAGGPRPPI-RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
             A G   P+   G+  P G PG Q L P +      +G P          PP   G  GP
Sbjct: 845  GAAGETGPMGERGHPGPPGPPGEQGL-PGTAGKEGTKGDPG---------PPGAPGKDGP 894

Query: 215  GPQNYGSGMRPPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGG 273
                  +G+R  P   G  +PG   GPG  G   P+       P  + SPG   G  G G
Sbjct: 895  ------AGLRGFPGERG--LPGTAGGPGLKGNEGPS-----GPPGPAGSPGER-GAAGSG 940

Query: 274  GPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP----GSDGPMGGMGGMEPH 329
            GP G P  P P     ++            G      P+GP    G  GP+G  G   P 
Sbjct: 941  GPIGPPGRPGPQGPPGAAGE---------KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 991

Query: 330  HMNGSLG-SGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             + G  G  G++    +       G   PPG P   G +G
Sbjct: 992  GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 85/322 (26%), Positives = 106/322 (32%), Gaps = 71/322 (22%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHN---PSS--MMGPHSQPFMSP-RY--A 157
           PP    P G I P   QG PG    P  + PP     P S    GP     M P R+   
Sbjct: 314 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 373

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLL-----PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPM 212
           GG + P+    +        Q  L     P  M  T + G     GS         +GP 
Sbjct: 374 GGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ 433

Query: 213 GP-GPQNYGSGMRPPPNSLG-------------PAMPGI-----------------NMGP 241
           GP GPQ    G+  PP   G             P  PG+                 + G 
Sbjct: 434 GPRGPQ----GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 489

Query: 242 GAGRPWPNPNSAN------------SIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADS 287
              +  P P   +             +P  S   G     GPPG  GPPG   M  P   
Sbjct: 490 TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 549

Query: 288 TNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KN 346
             S   +     P PPG   +     PG+ G  G  G + PH   G  G   + G+P  +
Sbjct: 550 KGS---LGPQGEPGPPGQQGT-----PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 601

Query: 347 SPNNISGISNPPGTPRDDGELG 368
            P    G   PPGT  + G  G
Sbjct: 602 GPPGHPGKEGPPGTKGNQGPSG 623



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 71/249 (28%), Positives = 86/249 (34%), Gaps = 41/249 (16%)

Query: 97   APSPVLGNIPPND-------GMPGGPIPPGF--FQGPPGSQPSPHAQPP--PHNPSSMMG 145
            +P P   N PP         G PG     G    +G PG+  +P    P  P  P+   G
Sbjct: 1218 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1277

Query: 146  PHSQPFMSPRYAGGPRPPIRMGNQPPGGV-PGTQPLLPNSMDPTRQQGHPNMGGSMQRMN 204
            P     +        RP       PPG V P   P L        ++GHP + G +    
Sbjct: 1278 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI---G 1334

Query: 205  PPRGMGPMG----PGPQNYGS--GMRPPPNSLGPAMPGINMGPGAGRPWP-NPNSANSIP 257
            PP   G  G    PGPQ      G    P + GP  PG   GP  G P P  P  A    
Sbjct: 1335 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG---GP-PGLPGPAGPKGAKGAT 1390

Query: 258  YSSSSPGT--YVGPPGGGGPPGTPIMPSPADSTNSS------DNIYTMINPVPPGGSRSN 309
                  G     GPPG  GPPG  I P P      +        +      +P GG+   
Sbjct: 1391 GPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGA--- 1447

Query: 310  FPMGPGSDG 318
                PGS G
Sbjct: 1448 ----PGSPG 1452


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 84/311 (27%), Positives = 110/311 (35%), Gaps = 50/311 (16%)

Query: 98   PSPVLGNI-PPND-GMPGGPIPPGFFQGPPG--------------SQPSPHAQPPPHNPS 141
            P   +GN+ PP + G PG    PG  QG PG               QP     P P  P+
Sbjct: 1092 PPGGVGNLGPPGEKGEPGESGSPGI-QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150

Query: 142  SMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNM 196
               GP   P     + G P PP   G +   G  G      +P  P S  PT + G P  
Sbjct: 1151 GDDGPKGNPG-PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1209

Query: 197  GGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSI 256
             G       P   G  G      G G +  P ++G       +GP      P P+    +
Sbjct: 1210 LGKRGPAGSPGSEGRQG------GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1263

Query: 257  PYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDN--IYTMINPVPPGGSRSN 309
            P S    G        GPPG  GPPG P +   A +     +  +  +I P    G + +
Sbjct: 1264 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1323

Query: 310  FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISN 356
              + PG  G  G  G M     +G +G G   GLP                P    G+  
Sbjct: 1324 RGL-PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1382

Query: 357  PPGTPRDDGEL 367
            PPG P   GE+
Sbjct: 1383 PPGHPGPPGEV 1393



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 86/303 (28%), Positives = 107/303 (35%), Gaps = 65/303 (21%)

Query: 109 DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRM 166
           DG PG  G I     +G  G  P    +  P  P    GP           G P PP  M
Sbjct: 634 DGFPGFKGDIGVKGDRGEVGV-PGSRGEDGPEGPKGRTGP----------TGDPGPPGLM 682

Query: 167 GNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGS--------MQRMNPPRG-MGPMGP--- 214
           G +   GVPG  P  P    P    G P   G+        +   + PRG  GP GP   
Sbjct: 683 GEKGKLGVPGL-PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ 741

Query: 215 -GPQ-----------NYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSS 261
            GP+           + G G   PP   G P   G N  PG   P P P   + +P    
Sbjct: 742 RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-PGPPGKDGLPGHPG 800

Query: 262 SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--------------GSR 307
             G  VG  G  GPPG P +  P  +   +  +    +P PPG              G++
Sbjct: 801 QRGE-VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 859

Query: 308 SN--FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
            +   P  PG DGP G  G      + G+ G   + G          G S PPG     G
Sbjct: 860 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG--------NEGPSGPPGPAGSPG 911

Query: 366 ELG 368
           E G
Sbjct: 912 ERG 914



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 78/279 (27%), Positives = 90/279 (32%), Gaps = 32/279 (11%)

Query: 110  GMPGGPIPPGFFQ--------GPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR 161
            G+PG   PPG           G PG Q         H P    GP   P   P  AG   
Sbjct: 962  GLPGPAGPPGVAGEDGDKGEVGDPG-QKGTKGNKGEHGPPGPPGPIG-PVGQPGAAGADG 1019

Query: 162  PPIRMGNQPPGGVPGTQPL--LPNSMDPTRQQGHPNMGGSMQR------MNPPRGMGPMG 213
             P   G Q   G  G +          P   QG P   G          M PP   GP G
Sbjct: 1020 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079

Query: 214  PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS--SSPGTYVGPPG 271
            P   N   G + PP  +G      N+GP   +  P  + +  I        P    G  G
Sbjct: 1080 PAGPNGADGPQGPPGGVG------NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133

Query: 272  GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHM 331
              G PG P  P P   T          NP P G      P  PG  GP G  G       
Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDG---PKGNPGPVGFPGD--PGPPGEGGPRGQDGAKGDRGE 1188

Query: 332  NGSLGS-GDIDGLPKNSPNNISGISNPPGTPRDDGELGG 369
            +G  G  G      +N P    G   P G+P  +G  GG
Sbjct: 1189 DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG 1227



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 78/287 (27%), Positives = 97/287 (33%), Gaps = 53/287 (18%)

Query: 122 QGPPG-----SQPSPHAQPP---------------PHNPSSMMGPHSQPFMSPRYA---- 157
           +GPPG      +P P  QP                P  P  + GP  +     R      
Sbjct: 379 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438

Query: 158 -GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-- 214
            G P  P   G++   G+PG    LP       ++GH    G+     PP   G  G   
Sbjct: 439 RGMPGDPGVKGDRGFDGLPG----LPG------EKGHRGDTGAQGLPGPPGEDGERGDDG 488

Query: 215 --GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272
             GP+    G   P   LGP  P    GP   R    P      P  S  P    GPPG 
Sbjct: 489 EIGPRGL-PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG----PKGSLGPQGEPGPPGQ 543

Query: 273 GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHM 331
            G PGT  +P P  +            P  PG   S+ P G PG +GP G  G   P   
Sbjct: 544 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 603

Query: 332 NGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQND 378
            G LG           P  + G+    G     GE G +    F+ D
Sbjct: 604 QGPLG--------YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGD 642



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 80/280 (28%), Positives = 103/280 (36%), Gaps = 51/280 (18%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSM--------MGPHSQP-FMSPR 155
            PP + G+PG P  P  F GP G    P     P +P            GP   P  + P+
Sbjct: 765  PPGERGLPG-PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 823

Query: 156  YAGGPRPPI-RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
             A G   P+   G+  P G PG Q L P +      +G P          PP   G  GP
Sbjct: 824  GAAGETGPMGERGHPGPPGPPGEQGL-PGTAGKEGTKGDPG---------PPGAPGKDGP 873

Query: 215  GPQNYGSGMRPPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGG 273
                  +G+R  P   G  +PG   GPG  G   P+       P  + SPG   G  G G
Sbjct: 874  ------AGLRGFPGERG--LPGTAGGPGLKGNEGPS-----GPPGPAGSPGER-GAAGSG 919

Query: 274  GPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP----GSDGPMGGMGGMEPH 329
            GP G P  P P     ++            G      P+GP    G  GP+G  G   P 
Sbjct: 920  GPIGPPGRPGPQGPPGAAGE---------KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 970

Query: 330  HMNGSLG-SGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             + G  G  G++    +       G   PPG P   G +G
Sbjct: 971  GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 85/322 (26%), Positives = 106/322 (32%), Gaps = 71/322 (22%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHN---PSS--MMGPHSQPFMSP-RY--A 157
           PP    P G I P   QG PG    P  + PP     P S    GP     M P R+   
Sbjct: 293 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 352

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLL-----PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPM 212
           GG + P+    +        Q  L     P  M  T + G     GS         +GP 
Sbjct: 353 GGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ 412

Query: 213 GP-GPQNYGSGMRPPPNSLG-------------PAMPGI-----------------NMGP 241
           GP GPQ    G+  PP   G             P  PG+                 + G 
Sbjct: 413 GPRGPQ----GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 468

Query: 242 GAGRPWPNPNSAN------------SIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADS 287
              +  P P   +             +P  S   G     GPPG  GPPG   M  P   
Sbjct: 469 TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528

Query: 288 TNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KN 346
             S   +     P PPG   +     PG+ G  G  G + PH   G  G   + G+P  +
Sbjct: 529 KGS---LGPQGEPGPPGQQGT-----PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 580

Query: 347 SPNNISGISNPPGTPRDDGELG 368
            P    G   PPGT  + G  G
Sbjct: 581 GPPGHPGKEGPPGTKGNQGPSG 602



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 71/249 (28%), Positives = 86/249 (34%), Gaps = 41/249 (16%)

Query: 97   APSPVLGNIPPND-------GMPGGPIPPGF--FQGPPGSQPSPHAQPP--PHNPSSMMG 145
            +P P   N PP         G PG     G    +G PG+  +P    P  P  P+   G
Sbjct: 1197 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1256

Query: 146  PHSQPFMSPRYAGGPRPPIRMGNQPPGGV-PGTQPLLPNSMDPTRQQGHPNMGGSMQRMN 204
            P     +        RP       PPG V P   P L        ++GHP + G +    
Sbjct: 1257 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI---G 1313

Query: 205  PPRGMGPMG----PGPQNYGS--GMRPPPNSLGPAMPGINMGPGAGRPWP-NPNSANSIP 257
            PP   G  G    PGPQ      G    P + GP  PG   GP  G P P  P  A    
Sbjct: 1314 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG---GP-PGLPGPAGPKGAKGAT 1369

Query: 258  YSSSSPGT--YVGPPGGGGPPGTPIMPSPADSTNSS------DNIYTMINPVPPGGSRSN 309
                  G     GPPG  GPPG  I P P      +        +      +P GG+   
Sbjct: 1370 GPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGA--- 1426

Query: 310  FPMGPGSDG 318
                PGS G
Sbjct: 1427 ----PGSPG 1431



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 78/297 (26%), Positives = 97/297 (32%), Gaps = 58/297 (19%)

Query: 122 QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR--PPIRMGNQPPGGVPGTQP 179
           Q P  +Q SP  QP   +      P SQ    PR   G +  P +        G PG + 
Sbjct: 239 QQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEG 298

Query: 180 LLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQ--------NYGSG----- 222
                + P   QG+P   G      PP   G  G    PGP          +GSG     
Sbjct: 299 -PAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG 357

Query: 223 --------------------MRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSS 261
                               +R PP  +G    PG    PG+  P     S +  P    
Sbjct: 358 PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGS--PGLKGESGDLGPQGPR 415

Query: 262 SPGTYVGPPGGGGPPGTP----IMPSPADSTNSSDNIYTMINPVP-PGGSRSN-----FP 311
            P    GPPG  G  G          P D     D  +  +  +P   G R +      P
Sbjct: 416 GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 475

Query: 312 MGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             PG DG  G  G + P  + G  G   + G PK  P    GI  PPG    DG  G
Sbjct: 476 GPPGEDGERGDDGEIGPRGLPGESGPRGLLG-PKGPP----GIPGPPGVRGMDGPQG 527


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 84/311 (27%), Positives = 110/311 (35%), Gaps = 50/311 (16%)

Query: 98   PSPVLGNI-PPND-GMPGGPIPPGFFQGPPG--------------SQPSPHAQPPPHNPS 141
            P   +GN+ PP + G PG    PG  QG PG               QP     P P  P+
Sbjct: 1199 PPGGVGNLGPPGEKGEPGESGSPGI-QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1257

Query: 142  SMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNM 196
               GP   P     + G P PP   G +   G  G      +P  P S  PT + G P  
Sbjct: 1258 GDDGPKGNPG-PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP 1316

Query: 197  GGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSI 256
             G       P   G  G      G G +  P ++G       +GP      P P+    +
Sbjct: 1317 LGKRGPAGSPGSEGRQG------GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1370

Query: 257  PYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNSSDN--IYTMINPVPPGGSRSN 309
            P S    G        GPPG  GPPG P +   A +     +  +  +I P    G + +
Sbjct: 1371 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1430

Query: 310  FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISN 356
              + PG  G  G  G M     +G +G G   GLP                P    G+  
Sbjct: 1431 RGL-PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1489

Query: 357  PPGTPRDDGEL 367
            PPG P   GE+
Sbjct: 1490 PPGHPGPPGEV 1500



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 86/303 (28%), Positives = 107/303 (35%), Gaps = 65/303 (21%)

Query: 109  DGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRM 166
            DG PG  G I     +G  G  P    +  P  P    GP           G P PP  M
Sbjct: 741  DGFPGFKGDIGVKGDRGEVGV-PGSRGEDGPEGPKGRTGP----------TGDPGPPGLM 789

Query: 167  GNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGS--------MQRMNPPRG-MGPMGP--- 214
            G +   GVPG  P  P    P    G P   G+        +   + PRG  GP GP   
Sbjct: 790  GEKGKLGVPGL-PGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ 848

Query: 215  -GPQ-----------NYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSS 261
             GP+           + G G   PP   G P   G N  PG   P P P   + +P    
Sbjct: 849  RGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP-PGPPGKDGLPGHPG 907

Query: 262  SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--------------GSR 307
              G  VG  G  GPPG P +  P  +   +  +    +P PPG              G++
Sbjct: 908  QRGE-VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 966

Query: 308  SN--FPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
             +   P  PG DGP G  G      + G+ G   + G          G S PPG     G
Sbjct: 967  GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG--------NEGPSGPPGPAGSPG 1018

Query: 366  ELG 368
            E G
Sbjct: 1019 ERG 1021



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 78/279 (27%), Positives = 90/279 (32%), Gaps = 32/279 (11%)

Query: 110  GMPGGPIPPGFFQ--------GPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR 161
            G+PG   PPG           G PG Q         H P    GP   P   P  AG   
Sbjct: 1069 GLPGPAGPPGVAGEDGDKGEVGDPG-QKGTKGNKGEHGPPGPPGPIG-PVGQPGAAGADG 1126

Query: 162  PPIRMGNQPPGGVPGTQPL--LPNSMDPTRQQGHPNMGGSMQR------MNPPRGMGPMG 213
             P   G Q   G  G +          P   QG P   G          M PP   GP G
Sbjct: 1127 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1186

Query: 214  PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSS--SSPGTYVGPPG 271
            P   N   G + PP  +G      N+GP   +  P  + +  I        P    G  G
Sbjct: 1187 PAGPNGADGPQGPPGGVG------NLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240

Query: 272  GGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHM 331
              G PG P  P P   T          NP P G      P  PG  GP G  G       
Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDG---PKGNPGPVGFPGD--PGPPGEGGPRGQDGAKGDRGE 1295

Query: 332  NGSLGS-GDIDGLPKNSPNNISGISNPPGTPRDDGELGG 369
            +G  G  G      +N P    G   P G+P  +G  GG
Sbjct: 1296 DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG 1334



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 78/287 (27%), Positives = 97/287 (33%), Gaps = 53/287 (18%)

Query: 122 QGPPG-----SQPSPHAQPP---------------PHNPSSMMGPHSQPFMSPRYA---- 157
           +GPPG      +P P  QP                P  P  + GP  +     R      
Sbjct: 486 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545

Query: 158 -GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-- 214
            G P  P   G++   G+PG    LP       ++GH    G+     PP   G  G   
Sbjct: 546 RGMPGDPGVKGDRGFDGLPG----LPG------EKGHRGDTGAQGLPGPPGEDGERGDDG 595

Query: 215 --GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272
             GP+    G   P   LGP  P    GP   R    P      P  S  P    GPPG 
Sbjct: 596 EIGPRGL-PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG----PKGSLGPQGEPGPPGQ 650

Query: 273 GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHM 331
            G PGT  +P P  +            P  PG   S+ P G PG +GP G  G   P   
Sbjct: 651 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 710

Query: 332 NGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQND 378
            G LG           P  + G+    G     GE G +    F+ D
Sbjct: 711 QGPLG--------YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGD 749



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 80/280 (28%), Positives = 103/280 (36%), Gaps = 51/280 (18%)

Query: 106  PPND-GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSM--------MGPHSQP-FMSPR 155
            PP + G+PG P  P  F GP G    P     P +P            GP   P  + P+
Sbjct: 872  PPGERGLPG-PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 930

Query: 156  YAGGPRPPI-RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
             A G   P+   G+  P G PG Q L P +      +G P          PP   G  GP
Sbjct: 931  GAAGETGPMGERGHPGPPGPPGEQGL-PGTAGKEGTKGDPG---------PPGAPGKDGP 980

Query: 215  GPQNYGSGMRPPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGG 273
                  +G+R  P   G  +PG   GPG  G   P+       P  + SPG   G  G G
Sbjct: 981  ------AGLRGFPGERG--LPGTAGGPGLKGNEGPS-----GPPGPAGSPGER-GAAGSG 1026

Query: 274  GPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP----GSDGPMGGMGGMEPH 329
            GP G P  P P     ++            G      P+GP    G  GP+G  G   P 
Sbjct: 1027 GPIGPPGRPGPQGPPGAAGE---------KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 1077

Query: 330  HMNGSLG-SGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             + G  G  G++    +       G   PPG P   G +G
Sbjct: 1078 GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1117



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 85/322 (26%), Positives = 106/322 (32%), Gaps = 71/322 (22%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHN---PSS--MMGPHSQPFMSP-RY--A 157
           PP    P G I P   QG PG    P  + PP     P S    GP     M P R+   
Sbjct: 400 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 459

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLL-----PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPM 212
           GG + P+    +        Q  L     P  M  T + G     GS         +GP 
Sbjct: 460 GGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ 519

Query: 213 GP-GPQNYGSGMRPPPNSLG-------------PAMPGI-----------------NMGP 241
           GP GPQ    G+  PP   G             P  PG+                 + G 
Sbjct: 520 GPRGPQ----GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 575

Query: 242 GAGRPWPNPNSAN------------SIPYSSSSPGTY--VGPPGGGGPPGTPIMPSPADS 287
              +  P P   +             +P  S   G     GPPG  GPPG   M  P   
Sbjct: 576 TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 635

Query: 288 TNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KN 346
             S   +     P PPG   +     PG+ G  G  G + PH   G  G   + G+P  +
Sbjct: 636 KGS---LGPQGEPGPPGQQGT-----PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSD 687

Query: 347 SPNNISGISNPPGTPRDDGELG 368
            P    G   PPGT  + G  G
Sbjct: 688 GPPGHPGKEGPPGTKGNQGPSG 709



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 71/249 (28%), Positives = 86/249 (34%), Gaps = 41/249 (16%)

Query: 97   APSPVLGNIPPND-------GMPGGPIPPGF--FQGPPGSQPSPHAQPP--PHNPSSMMG 145
            +P P   N PP         G PG     G    +G PG+  +P    P  P  P+   G
Sbjct: 1304 SPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1363

Query: 146  PHSQPFMSPRYAGGPRPPIRMGNQPPGGV-PGTQPLLPNSMDPTRQQGHPNMGGSMQRMN 204
            P     +        RP       PPG V P   P L        ++GHP + G +    
Sbjct: 1364 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI---G 1420

Query: 205  PPRGMGPMG----PGPQNYGS--GMRPPPNSLGPAMPGINMGPGAGRPWP-NPNSANSIP 257
            PP   G  G    PGPQ      G    P + GP  PG   GP  G P P  P  A    
Sbjct: 1421 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG---GP-PGLPGPAGPKGAKGAT 1476

Query: 258  YSSSSPGT--YVGPPGGGGPPGTPIMPSPADSTNSS------DNIYTMINPVPPGGSRSN 309
                  G     GPPG  GPPG  I P P      +        +      +P GG+   
Sbjct: 1477 GPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGA--- 1533

Query: 310  FPMGPGSDG 318
                PGS G
Sbjct: 1534 ----PGSPG 1538



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 76/323 (23%), Positives = 91/323 (28%), Gaps = 76/323 (23%)

Query: 122 QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLL 181
           Q P  +Q SP  QP   +      P SQP  S  Y            +PP     T    
Sbjct: 239 QQPHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYY----------DYEPPYYDVMTTGTT 288

Query: 182 PNSMDPTRQQGHPNMGGSM---------QRMNPPR---------GMG----PMGPGPQNY 219
           P+  DPT  +    +  S+             PP          G G    P GP    Y
Sbjct: 289 PDYQDPTPGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTY 348

Query: 220 GSG-MRPPPNSLGPAMPGINMGPGAGRPWP-------------NPNSANSIPYSSSSPGT 265
           G G        LGPA+       GA    P              P      P     P  
Sbjct: 349 GYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 408

Query: 266 YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGS--------RSNFPMGP--- 314
            +GPPG  G PG    P        +    +   P PPG S              GP   
Sbjct: 409 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 468

Query: 315 ------------------GSDGPMGGMGGMEPHHMNGSLG-SGDIDGLPKNSPNNISGIS 355
                             G  GPMG  G   P    GS G  G+   L    P    G++
Sbjct: 469 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 528

Query: 356 NPPGTPRDDGELGGNFLHSFQND 378
            PPG     G  G +       D
Sbjct: 529 GPPGKAGRRGRAGADGARGMPGD 551


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 87/272 (31%), Positives = 102/272 (37%), Gaps = 29/272 (10%)

Query: 102  LGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR 161
            L  +P   G PG P  PG   G  GS   P     P  P    G   QP + P + G P 
Sbjct: 1075 LPGLPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTP----GAKGQPGL-PGFPGTPG 1128

Query: 162  PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS 221
            PP   G   P G PG    LP    P    GHP   G       P   G  GP  Q    
Sbjct: 1129 PPGPKGISGPPGNPG----LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 222  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 281
            G     N   P +PG++   G G   P       +P     PG + G PG  GPPG P  
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDG-GLPGIPGNPGLPGPKGEPG-FHGFPGVQGPPGPPGS 1242

Query: 282  PSPADSTNSSDNIYTMINPVPPG-GSRSNFPMGPGSDGPMG--GMGGMEPHHMNGSLGSG 338
            P PA             NP P G   R  F   PG +GP G  G GG++     G+ G  
Sbjct: 1243 PGPALEGPKG-------NPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGE--KGNPGQP 1293

Query: 339  DIDGLPKNSPNNISGISNPPGTPRDDGELGGN 370
             + GLP      + G   PPG   + G  G N
Sbjct: 1294 GLPGLP-----GLKGDQGPPGLQGNPGRPGLN 1320



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 88/288 (30%), Positives = 107/288 (37%), Gaps = 39/288 (13%)

Query: 106 PPNDGMPG-----GPI-PPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQPFMSPRYA 157
           P N G+PG     GP+ PPGF  GPPG       Q    NP    + GP   P  +    
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG-PMGPGP 216
           G P  P   G     G+PG  P LP       Q G P + GS      P G+G P  PGP
Sbjct: 663 GKPGLPGNPGRDGDVGLPG-DPGLPG------QPGLPGIPGSKGEPGIP-GIGLPGPPGP 714

Query: 217 QNYGSGMRPPPNSLG-PAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGT--------- 265
           + +  G+  PP + G P   G+   PG  G P P      ++P     PG          
Sbjct: 715 KGF-PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP 773

Query: 266 -----YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 320
                + GPPG  G  G   +P P      +     M  P  PG      P  PG  GP+
Sbjct: 774 KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 321 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           G  G    H + G  G     GL    P    G    PG P   G  G
Sbjct: 834 GQPG---LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG 878



 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 99/315 (31%), Positives = 119/315 (37%), Gaps = 56/315 (17%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFM 152
           S  A   P L   P  DG+PG P P    +G PG       + PP NP     P +   M
Sbjct: 565 SPGAPGLPGLPGTPGQDGLPGLPGP----KGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 153 SPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSM-DPTR---QQGHPNMGGSMQRMNPPRG 208
            P   G P P    G Q   G PG QP +P    DP +   Q G P + G     NP R 
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPG-QPGIPGPKGDPGQTITQPGKPGLPG-----NPGRD 674

Query: 209 MGPMG-PGPQNYGS--GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPG 264
            G +G PG        G+   P S G P +PGI + PG     P P     IP    +PG
Sbjct: 675 -GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGL-PGP----PGPKGFPGIPGPPGAPG 728

Query: 265 TYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-----------GSRSNFPMG 313
           T  G  G  GPPG P  P P               P PPG           G R  FP  
Sbjct: 729 T-PGRIGLEGPPGPPGFPGP----KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGP 782

Query: 314 PGS------DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGEL 367
           PG       DG  G  G + P+   G +G   + G+       + G   PPG P   G +
Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI------GVQGPPGPPGIP---GPI 833

Query: 368 GGNFLHSFQNDNYSP 382
           G   LH    +   P
Sbjct: 834 GQPGLHGIPGEKGDP 848



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 90/319 (28%), Positives = 104/319 (32%), Gaps = 69/319 (21%)

Query: 103  GNIPPNDGMPGGPIPPGF----FQGPPGSQ--PSPHAQPPPHNPSSMMGPHSQPFMSPRY 156
            G++ PN G PG   PPG      QGPPG    P P  QP  H      G    P +    
Sbjct: 799  GDVGPN-GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV-- 855

Query: 157  AGGPRPPIRMGNQPPGGVPGT--QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG- 213
               P PP   G+    G PG    P  P         G P   G M  M PP   GP+G 
Sbjct: 856  ---PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 214  ---------------------PGPQNYGSGMRPP----------PNSLG-------PAMP 235
                                 PGP         P          PN LG       P +P
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 236  GINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNS 290
            GI   PG       P     +P     PG        GPPG  G PG P  P        
Sbjct: 973  GI---PGVS----GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025

Query: 291  SDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPN 349
               I  M  P P G      P G PG  G   G+ G +    +  + S  + GLP   P 
Sbjct: 1026 KGTIGDMGFPGPQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLPGLP--GPK 1082

Query: 350  NISGISNPPGTPRDDGELG 368
               G+   PG P   G +G
Sbjct: 1083 GEPGLPGYPGNPGIKGSVG 1101



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 85/295 (28%), Positives = 103/295 (34%), Gaps = 41/295 (13%)

Query: 99  SPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-------F 151
           S ++ ++P   G PG P PPG  QG PG    P    PP  P  +MGP   P        
Sbjct: 160 SIIMSSLPGPKGNPGYPGPPG-IQGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGN 217

Query: 152 MSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGP 211
           M   + G        G Q P G PG        +D   Q+G   + G      PP   GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 212 MG-PGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 269
            G PG +    G +  P   G P   G N  PG             IP     PG Y G 
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------IPGLPGDPG-YPGE 323

Query: 270 P---------GGGGPPGTP--IMPSPADSTNSSDNIYTMINPVPPGGSRSNFP---MGPG 315
           P         G  GPPG P  ++P P       +     +  +P       FP     PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 316 SDGPMGG--MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             GP G   MG   P    G  G    +G P  S     G+   PG P   G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 89/298 (29%), Positives = 105/298 (35%), Gaps = 38/298 (12%)

Query: 100  PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGG 159
            P L  +P   G  G P  PG F G PG         PP NP     P   P     + G 
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPG-FPGTPGPPGPKGISGPPGNPGLPGEP--GPVGGGGHPGQ 1159

Query: 160  PRPPIRMGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG- 213
            P PP   G     G+PG      +P  P   +P    G P + G       P   G  G 
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 214  PGPQN----YG----SGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT 265
            PGP+     +G     G   PP S GPA+ G    PG   P P       +P     PG 
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGP-PGRPGFQGLPGPEGPPGL 1277

Query: 266  YVGPPGGG------GPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRSN-----FPM 312
                PG G      G PG P +P                NP  PG  G + +      P 
Sbjct: 1278 ----PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG 1333

Query: 313  GPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNN--ISGISNPPGTPRDDGELG 368
             PG  GP G  G   P    G +G     GLP  S  +  I G + PPG P   G  G
Sbjct: 1334 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1391



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 85/297 (28%), Positives = 103/297 (34%), Gaps = 30/297 (10%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPG--SQPSPHAQPPPHNPSSMMGPHSQP 150
           AA    P     P   G  G   PPG    GPPG   QP     P P  P+   GPH  P
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA---GPHIPP 446

Query: 151 FMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMD------------PTRQQGHPNMGG 198
                  G P PP   G+    G+ G Q +  +  D            P  Q G P + G
Sbjct: 447 SDEICEPGPPGPP---GSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 199 SMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIP 257
               +  P   G  G        G+   P + G P  PG    PG    +P         
Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563

Query: 258 YSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNS---SDNIYTMINPVPPGGSRSNFPMGP 314
            S  +PG   G PG  G  G P +P P                 NP  PG   +  PMGP
Sbjct: 564 GSPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP 622

Query: 315 GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNI---SGISNPPGTPRDDGELG 368
              GP G +G      + G+ G   I G PK  P       G    PG P  DG++G
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPG-PKGDPGQTITQPGKPGLPGNPGRDGDVG 678



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 80/268 (29%), Positives = 102/268 (38%), Gaps = 47/268 (17%)

Query: 110 GMPGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMG 167
           G+PG P P    +GPPG   Q      P P  P  + GP   P   P   G P  P   G
Sbjct: 60  GLPGFPGP----EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF-PGTPGLPGMPGHDG 114

Query: 168 NQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 227
              P G+PG             ++G P   G      PP   GP G        GM+  P
Sbjct: 115 APGPQGIPGCN-------GTKGERGFPGSPGFPGLQGPP---GPPGI------PGMKGEP 158

Query: 228 NSL-GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGTPIMPSP 284
            S+   ++PG    PG    +P P     +P  +  PG     GPPG  GPPG P +P P
Sbjct: 159 GSIIMSSLPGPKGNPG----YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 285 ADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGM--EPHHMNGSLGSGDIDG 342
             +          +N   P G +       G  GP G  G +  +   ++     GD  G
Sbjct: 215 KGNMG--------LNFQGPKGEKGE----QGLQGPPGPPGQISEQKRPIDVEFQKGD-QG 261

Query: 343 LP-KNSPNNISGISNPPGTP-RDDGELG 368
           LP    P    GI  PPG P  + GE G
Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGEKGEKG 289



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 81/270 (30%), Positives = 106/270 (39%), Gaps = 45/270 (16%)

Query: 100  PVLGNIPPNDGMPGGPIPPG-FFQGPPGSQPSPHAQPPPHNP--SSMMGPHSQPFMSPRY 156
            P     P   G PG P  PG   +GP G   +P  Q PP  P    + GP   P +    
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKG---NPGPQGPPGRPGFQGLPGPEGPPGLPGN- 1280

Query: 157  AGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGP 216
             GG +     GN    G+PG  P L     P   QG+P   G    +N  +G  P  PG 
Sbjct: 1281 -GGIKG--EKGNPGQPGLPGL-PGLKGDQGPPGLQGNPGRPG----LNGMKG-DPGLPGV 1331

Query: 217  QNYGSGMRPP---PNSLGP-AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272
              +  GM+ P   P S GP   PG+ +GP      P P+  + I    +      GPPG 
Sbjct: 1332 PGF-PGMKGPSGVPGSAGPEGEPGL-IGPPGPPGLPGPSGQSIIIKGDA------GPPGI 1383

Query: 273  GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGG--SRSNFPMGPGSDGPMGGMGGMEPHH 330
             G PG   +P P            +  P  P G   R+  P   G+ G  G  G      
Sbjct: 1384 PGQPGLKGLPGPQGPQG-------LPGPTGPPGDPGRNGLPGFDGAGGRKGDPG------ 1430

Query: 331  MNGSLGSGDIDGLPKNSPNNISGISNPPGT 360
            + G  G+  +DG P   P+ + G   PPGT
Sbjct: 1431 LPGQPGTRGLDGPP--GPDGLQGPPGPPGT 1458



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 59/189 (31%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 191 QGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLG----PAMPGINMGPG 242
           +GHP + G      PP   G  G    PGP     G+R PP   G    P +PG+    G
Sbjct: 56  EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG-PKGIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 243 AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 302
           A  P   P   N        PG+  G PG  GPPG P +P       S   I     P P
Sbjct: 115 APGPQGIPG-CNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGS---IIMSSLPGP 169

Query: 303 PGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 362
            G         PG  GP G  G   P  + G +G           P  + G   PPG P 
Sbjct: 170 KGN--------PGYPGPPGIQGLPGPTGIPGPIGPP--------GPPGLMGPPGPPGLPG 213

Query: 363 DDGELGGNF 371
             G +G NF
Sbjct: 214 PKGNMGLNF 222



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 75/280 (26%), Positives = 90/280 (32%), Gaps = 80/280 (28%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPG--SQPSPHAQPPPHNPSSMMGPHSQPFMSP 154
            L  IP N G+PG    PGF      QGPPG    P P  + P  NP    GP   P   P
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP----GPQGPPGR-P 1263

Query: 155  RYAGGPRPPIRMGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNMGGSMQR------- 202
             + G P P    G    GG+ G      QP LP        QG P + G+  R       
Sbjct: 1264 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1323

Query: 203  -------------MNPPRGM-GPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPW- 247
                         M  P G+ G  GP  +    G   PP   GP+   I +   AG P  
Sbjct: 1324 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1383

Query: 248  ---------PNPNSANSIPYSSSSPGT-----------------------------YVGP 269
                     P P     +P  +  PG                                GP
Sbjct: 1384 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1443

Query: 270  PGGGG---PPGTPIMPSPADSTNSSDNIYTMINPVPPGGS 306
            PG  G   PPG P   S A     + +  T   P  P G+
Sbjct: 1444 PGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1483



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 39/124 (31%), Positives = 44/124 (35%), Gaps = 10/124 (8%)

Query: 268 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRS-----NFPMGPGSDGPM 320
           G PG  G PG P  P P               P PPG  G R       FP  PG  G  
Sbjct: 51  GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110

Query: 321 GGMGGMEPHHMNGSLGSGDIDGLPKNSPN--NISGISNPPGTPRDDGELGGNFLHSFQND 378
           G  G   P  + G  G+    G P  SP    + G   PPG P   GE G   + S    
Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFP-GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 379 NYSP 382
             +P
Sbjct: 170 KGNP 173


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 87/275 (31%), Positives = 102/275 (37%), Gaps = 32/275 (11%)

Query: 102  LGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR 161
            L  +P   G PG P  PG   G  GS   P     P  P    G   QP + P + G P 
Sbjct: 1075 LPGLPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTP----GAKGQPGL-PGFPGTPG 1128

Query: 162  PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS 221
            PP   G   P G PG    LP    P    GHP   G       P   G  GP  Q    
Sbjct: 1129 PPGPKGISGPPGNPG----LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 222  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 281
            G     N   P +PG++   G G   P       +P     PG + G PG  GPPG P  
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDG-GLPGIPGNPGLPGPKGEPG-FHGFPGVQGPPGPPGS 1242

Query: 282  PSPADSTNSSDNIYTMINPVPPGGSRSNFPMG----PGSDGPMG--GMGGMEPHHMNGSL 335
            P PA             NP P G      P G    PG +GP G  G GG++     G+ 
Sbjct: 1243 PGPALEGPKG-------NPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGE--KGNP 1293

Query: 336  GSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 370
            G   + GLP      + G   PPG   + G  G N
Sbjct: 1294 GQPGLPGLP-----GLKGDQGPPGLQGNPGRPGLN 1323



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 88/288 (30%), Positives = 107/288 (37%), Gaps = 39/288 (13%)

Query: 106 PPNDGMPG-----GPI-PPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQPFMSPRYA 157
           P N G+PG     GP+ PPGF  GPPG       Q    NP    + GP   P  +    
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG-PMGPGP 216
           G P  P   G     G+PG  P LP       Q G P + GS      P G+G P  PGP
Sbjct: 663 GKPGLPGNPGRDGDVGLPG-DPGLPG------QPGLPGIPGSKGEPGIP-GIGLPGPPGP 714

Query: 217 QNYGSGMRPPPNSLG-PAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGT--------- 265
           + +  G+  PP + G P   G+   PG  G P P      ++P     PG          
Sbjct: 715 KGF-PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP 773

Query: 266 -----YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 320
                + GPPG  G  G   +P P      +     M  P  PG      P  PG  GP+
Sbjct: 774 KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 321 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           G  G    H + G  G     GL    P    G    PG P   G  G
Sbjct: 834 GQPG---LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG 878



 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 99/315 (31%), Positives = 119/315 (37%), Gaps = 56/315 (17%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFM 152
           S  A   P L   P  DG+PG P P    +G PG       + PP NP     P +   M
Sbjct: 565 SPGAPGLPGLPGTPGQDGLPGLPGP----KGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 153 SPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSM-DPTR---QQGHPNMGGSMQRMNPPRG 208
            P   G P P    G Q   G PG QP +P    DP +   Q G P + G     NP R 
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPG-QPGIPGPKGDPGQTITQPGKPGLPG-----NPGRD 674

Query: 209 MGPMG-PGPQNYGS--GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPG 264
            G +G PG        G+   P S G P +PGI + PG     P P     IP    +PG
Sbjct: 675 -GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGL-PGP----PGPKGFPGIPGPPGAPG 728

Query: 265 TYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-----------GSRSNFPMG 313
           T  G  G  GPPG P  P P               P PPG           G R  FP  
Sbjct: 729 T-PGRIGLEGPPGPPGFPGP----KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGP 782

Query: 314 PGS------DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGEL 367
           PG       DG  G  G + P+   G +G   + G+       + G   PPG P   G +
Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI------GVQGPPGPPGIP---GPI 833

Query: 368 GGNFLHSFQNDNYSP 382
           G   LH    +   P
Sbjct: 834 GQPGLHGIPGEKGDP 848



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 90/300 (30%), Positives = 106/300 (35%), Gaps = 39/300 (13%)

Query: 100  PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGG 159
            P L  +P   G  G P  PG F G PG         PP NP     P   P     + G 
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPG-FPGTPGPPGPKGISGPPGNPGLPGEP--GPVGGGGHPGQ 1159

Query: 160  PRPPIRMGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG- 213
            P PP   G     G+PG      +P  P   +P    G P + G       P   G  G 
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 214  PGPQN----YG----SGMRPPPNSLGPAMPGINMGPGAGRP--WPNPNSANSIPYSSSSP 263
            PGP+     +G     G   PP S GPA+ G    PG   P   P P     +P     P
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPP 1278

Query: 264  GTYVGPPGGG------GPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRSN-----F 310
            G     PG G      G PG P +P                NP  PG  G + +      
Sbjct: 1279 GL----PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1334

Query: 311  PMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNN--ISGISNPPGTPRDDGELG 368
            P  PG  GP G  G   P    G +G     GLP  S  +  I G + PPG P   G  G
Sbjct: 1335 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1394



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 90/319 (28%), Positives = 104/319 (32%), Gaps = 69/319 (21%)

Query: 103  GNIPPNDGMPGGPIPPGF----FQGPPGSQ--PSPHAQPPPHNPSSMMGPHSQPFMSPRY 156
            G++ PN G PG   PPG      QGPPG    P P  QP  H      G    P +    
Sbjct: 799  GDVGPN-GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV-- 855

Query: 157  AGGPRPPIRMGNQPPGGVPGT--QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG- 213
               P PP   G+    G PG    P  P         G P   G M  M PP   GP+G 
Sbjct: 856  ---PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 214  ---------------------PGPQNYGSGMRPP----------PNSLG-------PAMP 235
                                 PGP         P          PN LG       P +P
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 236  GINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNS 290
            GI   PG       P     +P     PG        GPPG  G PG P  P        
Sbjct: 973  GI---PGVS----GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025

Query: 291  SDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPN 349
               I  M  P P G      P G PG  G   G+ G +    +  + S  + GLP   P 
Sbjct: 1026 KGTIGDMGFPGPQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLPGLP--GPK 1082

Query: 350  NISGISNPPGTPRDDGELG 368
               G+   PG P   G +G
Sbjct: 1083 GEPGLPGYPGNPGIKGSVG 1101



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 85/295 (28%), Positives = 103/295 (34%), Gaps = 41/295 (13%)

Query: 99  SPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-------F 151
           S ++ ++P   G PG P PPG  QG PG    P    PP  P  +MGP   P        
Sbjct: 160 SIIMSSLPGPKGNPGYPGPPG-IQGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGN 217

Query: 152 MSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGP 211
           M   + G        G Q P G PG        +D   Q+G   + G      PP   GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 212 MG-PGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 269
            G PG +    G +  P   G P   G N  PG             IP     PG Y G 
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------IPGLPGDPG-YPGE 323

Query: 270 P---------GGGGPPGTP--IMPSPADSTNSSDNIYTMINPVPPGGSRSNFP---MGPG 315
           P         G  GPPG P  ++P P       +     +  +P       FP     PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 316 SDGPMGG--MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             GP G   MG   P    G  G    +G P  S     G+   PG P   G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 85/297 (28%), Positives = 103/297 (34%), Gaps = 30/297 (10%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPG--SQPSPHAQPPPHNPSSMMGPHSQP 150
           AA    P     P   G  G   PPG    GPPG   QP     P P  P+   GPH  P
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA---GPHIPP 446

Query: 151 FMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMD------------PTRQQGHPNMGG 198
                  G P PP   G+    G+ G Q +  +  D            P  Q G P + G
Sbjct: 447 SDEICEPGPPGPP---GSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 199 SMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIP 257
               +  P   G  G        G+   P + G P  PG    PG    +P         
Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563

Query: 258 YSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNS---SDNIYTMINPVPPGGSRSNFPMGP 314
            S  +PG   G PG  G  G P +P P                 NP  PG   +  PMGP
Sbjct: 564 GSPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP 622

Query: 315 GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNI---SGISNPPGTPRDDGELG 368
              GP G +G      + G+ G   I G PK  P       G    PG P  DG++G
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPG-PKGDPGQTITQPGKPGLPGNPGRDGDVG 678



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 80/268 (29%), Positives = 102/268 (38%), Gaps = 47/268 (17%)

Query: 110 GMPGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMG 167
           G+PG P P    +GPPG   Q      P P  P  + GP   P   P   G P  P   G
Sbjct: 60  GLPGFPGP----EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF-PGTPGLPGMPGHDG 114

Query: 168 NQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 227
              P G+PG             ++G P   G      PP   GP G        GM+  P
Sbjct: 115 APGPQGIPGCN-------GTKGERGFPGSPGFPGLQGPP---GPPGI------PGMKGEP 158

Query: 228 NSL-GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGTPIMPSP 284
            S+   ++PG    PG    +P P     +P  +  PG     GPPG  GPPG P +P P
Sbjct: 159 GSIIMSSLPGPKGNPG----YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 285 ADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGM--EPHHMNGSLGSGDIDG 342
             +          +N   P G +       G  GP G  G +  +   ++     GD  G
Sbjct: 215 KGNMG--------LNFQGPKGEKGE----QGLQGPPGPPGQISEQKRPIDVEFQKGD-QG 261

Query: 343 LP-KNSPNNISGISNPPGTP-RDDGELG 368
           LP    P    GI  PPG P  + GE G
Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGEKGEKG 289



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 81/270 (30%), Positives = 105/270 (38%), Gaps = 42/270 (15%)

Query: 100  PVLGNIPPNDGMPGGPIPPG-FFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAG 158
            P     P   G PG P  PG   +GP G+ P P   P    P+   G        P   G
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGN-PGPQGPPGRPGPTGFQG-------LPGPEG 1276

Query: 159  GPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQR--MNPPRGMGPMGPGP 216
             P  P   G +   G PG QP LP        QG P + G+  R  +N  +G  P  PG 
Sbjct: 1277 PPGLPGNGGIKGEKGNPG-QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG-DPGLPGV 1334

Query: 217  QNYGSGMRPP---PNSLGP-AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272
              +  GM+ P   P S GP   PG+ +GP      P P+  + I    +      GPPG 
Sbjct: 1335 PGF-PGMKGPSGVPGSAGPEGEPGL-IGPPGPPGLPGPSGQSIIIKGDA------GPPGI 1386

Query: 273  GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGG--SRSNFPMGPGSDGPMGGMGGMEPHH 330
             G PG   +P P            +  P  P G   R+  P   G+ G  G  G      
Sbjct: 1387 PGQPGLKGLPGPQGPQG-------LPGPTGPPGDPGRNGLPGFDGAGGRKGDPG------ 1433

Query: 331  MNGSLGSGDIDGLPKNSPNNISGISNPPGT 360
            + G  G+  +DG P   P+ + G   PPGT
Sbjct: 1434 LPGQPGTRGLDGPP--GPDGLQGPPGPPGT 1461



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 59/189 (31%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 191 QGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLG----PAMPGINMGPG 242
           +GHP + G      PP   G  G    PGP     G+R PP   G    P +PG+    G
Sbjct: 56  EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG-PKGIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 243 AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 302
           A  P   P   N        PG+  G PG  GPPG P +P       S   I     P P
Sbjct: 115 APGPQGIPG-CNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGS---IIMSSLPGP 169

Query: 303 PGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 362
            G         PG  GP G  G   P  + G +G           P  + G   PPG P 
Sbjct: 170 KGN--------PGYPGPPGIQGLPGPTGIPGPIGPP--------GPPGLMGPPGPPGLPG 213

Query: 363 DDGELGGNF 371
             G +G NF
Sbjct: 214 PKGNMGLNF 222



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 74/280 (26%), Positives = 90/280 (32%), Gaps = 77/280 (27%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPG--SQPSPHAQPPPHNPS------------- 141
            L  IP N G+PG    PGF      QGPPG    P P  + P  NP              
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGF 1268

Query: 142  -SMMGPHSQPFM-----------SPRYAGGPRPPIRMGNQPPGGVPGT-----------Q 178
              + GP   P +           +P   G P  P   G+Q P G+ G             
Sbjct: 1269 QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1328

Query: 179  PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP----GPQNYG---SGMRPPPNSLG 231
            P LP        +G   + GS      P  +GP GP    GP        G   PP    
Sbjct: 1329 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI-- 1386

Query: 232  PAMPGINMGPGAGRPW--------PNPNSANSIPYSSSS------------PGTY----- 266
            P  PG+   PG   P         P     N +P    +            PGT      
Sbjct: 1387 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1446

Query: 267  VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGS 306
             GP G  GPPG P   S A     + +  T   P  P G+
Sbjct: 1447 PGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1486



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 39/124 (31%), Positives = 44/124 (35%), Gaps = 10/124 (8%)

Query: 268 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRS-----NFPMGPGSDGPM 320
           G PG  G PG P  P P               P PPG  G R       FP  PG  G  
Sbjct: 51  GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110

Query: 321 GGMGGMEPHHMNGSLGSGDIDGLPKNSPN--NISGISNPPGTPRDDGELGGNFLHSFQND 378
           G  G   P  + G  G+    G P  SP    + G   PPG P   GE G   + S    
Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFP-GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 379 NYSP 382
             +P
Sbjct: 170 KGNP 173


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 87/289 (30%), Positives = 105/289 (36%), Gaps = 54/289 (18%)

Query: 110 GMPG--GPIPPGFFQGPPGSQP-----SPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRP 162
           G PG  GPI P   QGPPG +       P A   P  P  + G    P  +P  AG P P
Sbjct: 238 GFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPG-IPGTKGLPG-APGIAGPPGP 295

Query: 163 PI--------RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
           P           G + P G+PG  P       P    G P + G      PP  MGP GP
Sbjct: 296 PGFGKPGLPGLKGERGPAGLPGG-PGAKGEQGPAGLPGKPGLTG------PPGNMGPQGP 348

Query: 215 GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGG 274
                  G+  P    GPA P       AG  +P        P S   PG Y G PG  G
Sbjct: 349 KGIPGSHGLPGPKGETGPAGP-------AG--YPGAKGERGSPGSDGKPG-YPGKPGLDG 398

Query: 275 PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGS 334
           P G P +P P            +  PV P G++      PG +G  G  G        G 
Sbjct: 399 PKGNPGLPGPKGDPGVG-GPPGLPGPVGPAGAKGM----PGHNGEAGPRGAPGIPGTRGP 453

Query: 335 LGSGDIDGLP--KNSPNN-------------ISGISNPPGTPRDDGELG 368
           +G   I G P  K  P +             ++G + PPG P   G  G
Sbjct: 454 IGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSG 502



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 90/290 (31%), Positives = 101/290 (34%), Gaps = 49/290 (16%)

Query: 91  DYSAAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPGSQPSPHAQPPPHNPSSMMGPHSQ 149
           D   A  P P     PP  G PG P P G    G PG Q  P   P P       G    
Sbjct: 128 DVGPAGLPGP---RGPP--GPPGIPGPAGISVPGKPGQQ-GPTGAPGPRGFPGEKGAPGV 181

Query: 150 PFMSPRYA----GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNP 205
           P M+ +      G P  P   G   P G  G  P  P  +    + G P   G       
Sbjct: 182 PGMNGQKGEMGYGAPGRPGERGLPGPQGPTG--PSGPPGVGKRGENGVPGQPGIKGDRGF 239

Query: 206 PRGMGPMG-PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPG 264
           P  MGP+G PGPQ        PP   GP         G G+P      A   P     PG
Sbjct: 240 PGEMGPIGPPGPQG-------PPGERGP--------EGIGKP-----GAAGAPGQPGIPG 279

Query: 265 T--YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG----PGSDG 318
           T    G PG  GPPG P    P       +     + P  PG      P G    PG  G
Sbjct: 280 TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGL-PGGPGAKGEQGPAGLPGKPGLTG 338

Query: 319 PMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           P G MG   P  + GS       GLP   P   +G + P G P   GE G
Sbjct: 339 PPGNMGPQGPKGIPGS------HGLP--GPKGETGPAGPAGYPGAKGERG 380



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 73/222 (32%), Positives = 81/222 (36%), Gaps = 25/222 (11%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
           G+PGGP   G  QGP G    P    PP N    MGP   P   P   G P P    G  
Sbjct: 314 GLPGGPGAKGE-QGPAGLPGKPGLTGPPGN----MGPQG-PKGIPGSHGLPGPKGETGPA 367

Query: 170 PPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRP 225
            P G PG +           ++G P   G       P   GP G    PGP+    G+  
Sbjct: 368 GPAGYPGAKG----------ERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKG-DPGVGG 416

Query: 226 PPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSS--SPGTYVGPPGGGGPPGTPIMPS 283
           PP   GP  P    G         P  A  IP +     P    G PG  G PG+P  P 
Sbjct: 417 PPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPG 476

Query: 284 PADSTNSSDNIYTMINPVPPG-GSRSNFPMGPGSDGPMGGMG 324
           PA       N  T   P PPG    S  P  PG  GP G  G
Sbjct: 477 PAGIATKGLNGPTG-PPGPPGPRGHSGEPGLPGPPGPPGPPG 517



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 67/200 (33%), Positives = 75/200 (37%), Gaps = 36/200 (18%)

Query: 110 GMPGGPIPPGFF--QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFM-----SPRYAGGPRP 162
           G PG   PPG    QGP G  P  H  P P   +   GP   P       SP   G P  
Sbjct: 332 GKPGLTGPPGNMGPQGPKGI-PGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGY 390

Query: 163 PIRMGNQPPGGVPGTQ-----------PLLPNSMDPTRQQGHPNMGGSM-QRMNP--PRG 208
           P + G   P G PG             P LP  + P   +G P   G    R  P  P  
Sbjct: 391 PGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGT 450

Query: 209 MGPMGPG-----PQNYGSGMRP-PPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSS 262
            GP+GP      P + G    P PP   G A  G+N   G   P P P         S  
Sbjct: 451 RGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP-PGPRG------HSGE 503

Query: 263 PGTYVGPPGGGGPPGTPIMP 282
           PG   GPPG  GPPG  +MP
Sbjct: 504 PGL-PGPPGPPGPPGQAVMP 522



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 76/252 (30%), Positives = 89/252 (35%), Gaps = 31/252 (12%)

Query: 123 GPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLP 182
           GPPG    P   P P  P    G  S          GP  P  +G     G+PG     P
Sbjct: 63  GPPGPA-GPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK----P 117

Query: 183 NSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPPPNSLGPAMPGINMGP 241
               P   +G     G      PP   GP G PGP   G  +   P   GP       G 
Sbjct: 118 GERGPYGPKGDVGPAGLPGPRGPP---GPPGIPGPA--GISVPGKPGQQGPT------GA 166

Query: 242 GAGRPWPNPNSANSIPYSSSSPGTY-VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINP 300
              R +P    A  +P  +   G    G PG  G  G P    P   +          N 
Sbjct: 167 PGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENG 226

Query: 301 VP--PG--GSRSNFP--MGP-GSDGPMGGMGGMEPHHMN--GSLGSGDIDGLP--KNSPN 349
           VP  PG  G R  FP  MGP G  GP G  G   P  +   G+ G+    G+P  K  P 
Sbjct: 227 VPGQPGIKGDR-GFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP- 284

Query: 350 NISGISNPPGTP 361
              GI+ PPG P
Sbjct: 285 GAPGIAGPPGPP 296



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 58/178 (32%), Positives = 67/178 (37%), Gaps = 32/178 (17%)

Query: 198 GSMQRMNPPRGMGPMG-PGPQNYGSGMRPPPNSLGPAMPGINMGPGA-GRPWPNPNSANS 255
           G      PP   GP G PGP         PP   G   PG+   PG  G P P+      
Sbjct: 57  GEQGTPGPPGPAGPRGHPGPSG-------PPGKPGYGSPGLQGEPGLPGPPGPSAVGKPG 109

Query: 256 IPYSSSSPGTY--------VGP---PGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG 304
           +P     PG          VGP   PG  GPPG P +P PA        I     P   G
Sbjct: 110 VPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPA-------GISVPGKPGQQG 162

Query: 305 GSRSNFPMG-PGSDGPMG--GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPG 359
            + +  P G PG  G  G  GM G +     G+ G     GLP   P   +G S PPG
Sbjct: 163 PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLP--GPQGPTGPSGPPG 218



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 48/161 (29%), Positives = 57/161 (35%), Gaps = 21/161 (13%)

Query: 239 MGPGAGRPWPNPNSANSIPYSSSSPGTYV-------GPPGGGGPPGTPIMPSPADSTN-S 290
           M  G   P PN  +   IPY+  S G  V       GPPG  GP G P    P       
Sbjct: 27  MPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYG 86

Query: 291 SDNIYTMIN-PVPPGGSR------SNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGL 343
           S  +      P PPG S          P  PG  GP G  G + P  + G  G     G+
Sbjct: 87  SPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI 146

Query: 344 PKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSPSM 384
           P   P  IS     PG P   G  G      F  +  +P +
Sbjct: 147 P--GPAGIS----VPGKPGQQGPTGAPGPRGFPGEKGAPGV 181



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 20/95 (21%)

Query: 100 PVLGNIPPNDGMPGGPIPPGFF----------QGPPGSQPSPH---AQPPPHNPSSMMGP 146
           P +   P + G PG P PPG             GPPG  P P     +P    P    GP
Sbjct: 457 PGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPG-PPGPRGHSGEPGLPGPPGPPGP 515

Query: 147 HSQPFMSPRY-AGGPRP-----PIRMGNQPPGGVP 175
             Q  M   +   G RP     P+   NQ   G+P
Sbjct: 516 PGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 95/305 (31%), Positives = 115/305 (37%), Gaps = 41/305 (13%)

Query: 110 GMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAG--GPR-PPI 164
           G PG   PPG     GP GS  SP  Q PP  P  + G   +  + P   G  GP  PP 
Sbjct: 650 GEPGPHGPPGVPGSVGPKGSSGSPGPQGPP-GPVGLQGLRGEVGL-PGVKGDKGPMGPPG 707

Query: 165 RMGNQ----------PPG--GVPGT--QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG 210
             G+Q           PG  G+PG   +P    +M P    GH    G       P   G
Sbjct: 708 PKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRG 767

Query: 211 PMGPGPQNYGSGMRPPPNSLG----PAMPGINMGPGA-GRPWPNPNSAN-SIPYSSSSPG 264
           P GP       G+  P    G    P  PGI   PGA G+   +  S+  ++P     PG
Sbjct: 768 PPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPG 827

Query: 265 TYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG--G 322
             +GPPG   PPG P    PA      + +     P PPG      P  PG  GP G  G
Sbjct: 828 A-MGPPG---PPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG 883

Query: 323 MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSP 382
            G   P    GS  S        NS   +SG   PPG P   G+ G       Q +   P
Sbjct: 884 EGLPGPPGPPGSFLS--------NSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLP 935

Query: 383 SMTMS 387
             + S
Sbjct: 936 GFSTS 940



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 79/278 (28%), Positives = 99/278 (35%), Gaps = 37/278 (13%)

Query: 100  PVLGNIPPNDGMPGGP--IPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYA 157
            P +   P   G PG P    P   QG PG+   P  +  P  P  ++       ++    
Sbjct: 763  PGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLT--VP 820

Query: 158  GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQ 217
            G P PP  MG   P G PG          P    G P     +    PP   GP GP   
Sbjct: 821  GPPGPPGAMGPPGPPGAPG----------PAGPAGLPGHQEVLNLQGPPGPPGPRGPP-- 868

Query: 218  NYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPG 277
              G  +  PP   GP   G+   PG     P    +NS  + S  P    GPPG  GP G
Sbjct: 869  --GPSIPGPPGPRGPPGEGLPGPPGP----PGSFLSNSETFLSGPP----GPPGPPGPKG 918

Query: 278  TPIMPSPADSTNSSDNIYTMINPVPPGGSRS---NFPMGPGSDGPMGGMGGMEPHHMNGS 334
                P P             +      GS S   N    PG  GP G  G      + G+
Sbjct: 919  DQGPPGPRGHQGEQG-----LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGA 973

Query: 335  LG--SGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 370
            LG  SG  +G   +S   +SG   PPG P   G +  +
Sbjct: 974  LGIPSGPSEG-GSSSTMYVSGPPGPPGPPGPPGSISSS 1010



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 82/273 (30%), Positives = 101/273 (36%), Gaps = 55/273 (20%)

Query: 98   PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYA 157
            P P     PP  G PG P P G   G PG Q   + Q PP  P    GP   P  S    
Sbjct: 823  PGPPGAMGPP--GPPGAPGPAGP-AGLPGHQEVLNLQGPPGPP----GPRGPPGPSIPGP 875

Query: 158  GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GP 216
             GPR P   G   P G PG+   L NS   T   G P   G      PP   G  GP GP
Sbjct: 876  PGPRGPPGEGLPGPPGPPGS--FLSNS--ETFLSGPPGPPG------PPGPKGDQGPPGP 925

Query: 217  QNY-GSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGP 275
            + + G    P  ++ G +  G+N+    G P P                   GP G  G 
Sbjct: 926  RGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQ------------------GPKGDKGD 967

Query: 276  PGTPI---MPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMN 332
            PG P    +PS      SS  +Y    P PPG         PG  G +   G     +++
Sbjct: 968  PGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG--------PPGPPGSISSSGQEIQQYIS 1019

Query: 333  GSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
              + S  I        + +SG+  PPG P   G
Sbjct: 1020 EYMQSDSI-------RSYLSGVQGPPGPPGPPG 1045



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 67/233 (28%), Positives = 78/233 (33%), Gaps = 42/233 (18%)

Query: 158 GGPRPPIRMGNQPPGG---VPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
           G P P   MG+  P G    PGT P +P  +     QG     GS+     P   GPMG 
Sbjct: 567 GSPGPKGDMGSPGPKGDRGFPGT-PGIPGPLGHPGPQGPKGQKGSV---GDPGMEGPMG- 621

Query: 215 GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGG 274
             Q    G   P    GP   G     GA    P P+    +P S       VGP G  G
Sbjct: 622 --QRGREGPMGPRGEAGPPGSGEKGERGAAGE-PGPHGPPGVPGS-------VGPKGSSG 671

Query: 275 PPGTPIMPSPADSTNSSDNI---------YTMINPVPPGGSRSNFPMG----------PG 315
            PG    P P         +           M  P P G      P G          PG
Sbjct: 672 SPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPG 731

Query: 316 SDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           + G  G  G M P   +G  G     GL       + GI  PPG   D G+ G
Sbjct: 732 AVGEPGAKGAMGPAGPDGHQGPRGEQGL-----TGMPGIRGPPGPSGDPGKPG 779



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 76/329 (23%), Positives = 106/329 (32%), Gaps = 74/329 (22%)

Query: 105  IPPNDGMPGGPIPPG-----FFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGG 159
            +P   G+P GP   G     +  GPPG    P   P P    S  G   Q ++S      
Sbjct: 970  VPGALGIPSGPSEGGSSSTMYVSGPPG----PPGPPGPPGSISSSGQEIQQYISEYMQSD 1025

Query: 160  PRPPIRMGNQPPGGVPG----TQPLLPNSMDPTRQQGH-------PNMGGSM-------- 200
                   G Q P G PG       +   + D +    H          G S+        
Sbjct: 1026 SIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSE 1085

Query: 201  ----------------QRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAG 244
                            Q +  PRG  P  PG    GS +      L   +       G  
Sbjct: 1086 DILAVLQRDDVRQYLRQYLMGPRGP-PGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS 1144

Query: 245  RPWPNPNSANSIPYSS----------SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNI 294
               P P     +P +S          S     VGPPG  GPPG   +P    S+ S +++
Sbjct: 1145 IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPG---IPGNVWSSISVEDL 1201

Query: 295  YTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPK--------- 345
             + ++        +     PG  GP G  G   P  ++G+L +   +             
Sbjct: 1202 SSYLHT-------AGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYL 1254

Query: 346  NSPNNISGISNPPGTPRDDGELGGNFLHS 374
             SP+  S I  PPG P   G  G + L S
Sbjct: 1255 TSPDVRSFIVGPPGPPGPQGPPGDSRLLS 1283



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 13/104 (12%)

Query: 268 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGM 326
           GP G  G PGTP +P P            + +P P G       +G PG +GPMG  G  
Sbjct: 579 GPKGDRGFPGTPGIPGP------------LGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626

Query: 327 EPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGN 370
            P    G  G        +       G   PPG P   G  G +
Sbjct: 627 GPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSS 670



 Score = 37.0 bits (84), Expect = 0.030
 Identities = 68/303 (22%), Positives = 89/303 (29%), Gaps = 82/303 (27%)

Query: 110  GMPGGPIPPG------------------------FFQGPPGSQPSPHAQPPPHNPSSMMG 145
            G PG P PPG                        F  GPPG    P   P P  P  + G
Sbjct: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPG----PPGPPGPRGPPGVSG 1233

Query: 146  -------PHSQPFMSPRYAGGPRPPIRM------GNQPPGGVPGTQPLLPNSMDPTRQQG 192
                    +S  F S   +    P +R       G   P G PG   LL      +R   
Sbjct: 1234 ALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSS 1293

Query: 193  HPNMGGSMQR---MNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWP- 248
              +   S++R    +     G  G G    G          GP   G ++GPG G     
Sbjct: 1294 SSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPY--GTDIGPGGGYGAAA 1351

Query: 249  ------------NPNSANSIPYS----------------SSSPGTYVGPPGGGGPPGTP- 279
                          + A  + Y+                     T  GPPG  GP G P 
Sbjct: 1352 EGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPG 1411

Query: 280  ---IMPSPADSTNSSDNIYTMINPV--PPGGSRSNFPMGP-GSDGPMGGMGGMEPHHMNG 333
               +  + ++ T    + +     +  PPG        GP G  GP G  G   P    G
Sbjct: 1412 ISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRG 1471

Query: 334  SLG 336
              G
Sbjct: 1472 HKG 1474



 Score = 35.4 bits (80), Expect = 0.088
 Identities = 54/216 (25%), Positives = 75/216 (34%), Gaps = 35/216 (16%)

Query: 155  RYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
            +Y  GPR P       P G  G   LL         +    M  S   +  P   GP G 
Sbjct: 1102 QYLMGPRGP-----PGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGL 1156

Query: 215  GPQNY--------GS---GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSP 263
               +Y        GS   G+  PP   GP  PGI      G  W + +  +   Y  ++ 
Sbjct: 1157 PGTSYEELLSLLRGSEFRGIVGPPGPPGP--PGI-----PGNVWSSISVEDLSSYLHTAG 1209

Query: 264  GTYV-------GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGS 316
             +++       GPPG  GPPG     +   + NS      +I+ +     RS     PG 
Sbjct: 1210 LSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGP 1269

Query: 317  DGPMGGMG-----GMEPHHMNGSLGSGDIDGLPKNS 347
             GP G  G       +  H  GS  S     + + S
Sbjct: 1270 PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGS 1305



 Score = 32.3 bits (72), Expect = 0.75
 Identities = 61/225 (27%), Positives = 84/225 (37%), Gaps = 55/225 (24%)

Query: 110  GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
            G+PG P PPG     PG+             S + G   +  + P     P PP      
Sbjct: 1146 GLPGPPGPPGL----PGTSYEELL-------SLLRGSEFRGIVGP-----PGPP------ 1183

Query: 170  PPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNS 229
             P G+PG    + +S+       + +  G      PP   GP G            PP  
Sbjct: 1184 GPPGIPGN---VWSSISVEDLSSYLHTAGLSFIPGPP---GPPG------------PPGP 1225

Query: 230  LGPAMPGINMGPGAGRPWPNPNSANS--IPYSSSSP--GTYVGPPGGGGPPGTP-----I 280
             GP  PG++ G  A     N +S  S  I Y +S       VGPPG  GP G P     +
Sbjct: 1226 RGP--PGVS-GALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLL 1282

Query: 281  MPSPADSTNSSDNIYTMINPVPPGGS-RSNFPMGPGSDGPMGGMG 324
                + S  SS + ++  + V  G S  S+   G G  G +G  G
Sbjct: 1283 STDASHSRGSSSSSHS--SSVRRGSSYSSSMSTGGGGAGSLGAGG 1325


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 86/271 (31%), Positives = 101/271 (37%), Gaps = 30/271 (11%)

Query: 102  LGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR 161
            L  +P   G PG P  PG   G  GS   P     P  P    G   QP + P + G P 
Sbjct: 1075 LPGLPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTP----GAKGQPGL-PGFPGTPG 1128

Query: 162  PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGS 221
            PP   G   P G PG    LP    P    GHP   G       P   G  GP  Q    
Sbjct: 1129 PPGPKGISGPPGNPG----LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 222  GMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 281
            G     N   P +PG++   G G   P       +P     PG + G PG  GPPG P  
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDG-GLPGIPGNPGLPGPKGEPG-FHGFPGVQGPPGPPGS 1242

Query: 282  PSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG--GMGGMEPHHMNGSLGSGD 339
            P PA             NP P G      P  PG +GP G  G GG++     G+ G   
Sbjct: 1243 PGPALEGPKG-------NPGPQG--PPGRPGLPGPEGPPGLPGNGGIKGE--KGNPGQPG 1291

Query: 340  IDGLPKNSPNNISGISNPPGTPRDDGELGGN 370
            + GLP      + G   PPG   + G  G N
Sbjct: 1292 LPGLP-----GLKGDQGPPGLQGNPGRPGLN 1317



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 88/288 (30%), Positives = 107/288 (37%), Gaps = 39/288 (13%)

Query: 106 PPNDGMPG-----GPI-PPGFFQGPPGSQPSPHAQPPPHNPSS--MMGPHSQPFMSPRYA 157
           P N G+PG     GP+ PPGF  GPPG       Q    NP    + GP   P  +    
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG-PMGPGP 216
           G P  P   G     G+PG  P LP       Q G P + GS      P G+G P  PGP
Sbjct: 663 GKPGLPGNPGRDGDVGLPG-DPGLPG------QPGLPGIPGSKGEPGIP-GIGLPGPPGP 714

Query: 217 QNYGSGMRPPPNSLG-PAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGT--------- 265
           + +  G+  PP + G P   G+   PG  G P P      ++P     PG          
Sbjct: 715 KGF-PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP 773

Query: 266 -----YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPM 320
                + GPPG  G  G   +P P      +     M  P  PG      P  PG  GP+
Sbjct: 774 KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 321 GGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           G  G    H + G  G     GL    P    G    PG P   G  G
Sbjct: 834 GQPG---LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG 878



 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 99/315 (31%), Positives = 119/315 (37%), Gaps = 56/315 (17%)

Query: 93  SAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFM 152
           S  A   P L   P  DG+PG P P    +G PG       + PP NP     P +   M
Sbjct: 565 SPGAPGLPGLPGTPGQDGLPGLPGP----KGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 153 SPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSM-DPTR---QQGHPNMGGSMQRMNPPRG 208
            P   G P P    G Q   G PG QP +P    DP +   Q G P + G     NP R 
Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPG-QPGIPGPKGDPGQTITQPGKPGLPG-----NPGRD 674

Query: 209 MGPMG-PGPQNYGS--GMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPG 264
            G +G PG        G+   P S G P +PGI + PG     P P     IP    +PG
Sbjct: 675 -GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGL-PGP----PGPKGFPGIPGPPGAPG 728

Query: 265 TYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-----------GSRSNFPMG 313
           T  G  G  GPPG P  P P               P PPG           G R  FP  
Sbjct: 729 T-PGRIGLEGPPGPPGFPGP----KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGP 782

Query: 314 PGS------DGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGEL 367
           PG       DG  G  G + P+   G +G   + G+       + G   PPG P   G +
Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI------GVQGPPGPPGIP---GPI 833

Query: 368 GGNFLHSFQNDNYSP 382
           G   LH    +   P
Sbjct: 834 GQPGLHGIPGEKGDP 848



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 90/319 (28%), Positives = 104/319 (32%), Gaps = 69/319 (21%)

Query: 103  GNIPPNDGMPGGPIPPGF----FQGPPGSQ--PSPHAQPPPHNPSSMMGPHSQPFMSPRY 156
            G++ PN G PG   PPG      QGPPG    P P  QP  H      G    P +    
Sbjct: 799  GDVGPN-GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV-- 855

Query: 157  AGGPRPPIRMGNQPPGGVPGT--QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG- 213
               P PP   G+    G PG    P  P         G P   G M  M PP   GP+G 
Sbjct: 856  ---PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 214  ---------------------PGPQNYGSGMRPP----------PNSLG-------PAMP 235
                                 PGP         P          PN LG       P +P
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 236  GINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YVGPPGGGGPPGTPIMPSPADSTNS 290
            GI   PG       P     +P     PG        GPPG  G PG P  P        
Sbjct: 973  GI---PGVS----GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025

Query: 291  SDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPN 349
               I  M  P P G      P G PG  G   G+ G +    +  + S  + GLP   P 
Sbjct: 1026 KGTIGDMGFPGPQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLPGLP--GPK 1082

Query: 350  NISGISNPPGTPRDDGELG 368
               G+   PG P   G +G
Sbjct: 1083 GEPGLPGYPGNPGIKGSVG 1101



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 91/290 (31%), Positives = 114/290 (39%), Gaps = 74/290 (25%)

Query: 102  LGNIPPNDGMPGGPIPPGFF-----QGPPGSQPSPHAQPPPHNPS-SMMGPHSQPFMSPR 155
            L  IP N G+PG    PGF      QGPPG         PP +P  ++ GP   P     
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPG---------PPGSPGPALEGPKGNP----- 1254

Query: 156  YAGGPR-PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
               GP+ PP R G   P G PG    LP +     ++G+P   G       P   G  GP
Sbjct: 1255 ---GPQGPPGRPGLPGPEGPPG----LPGNGGIKGEKGNPGQPGLP---GLPGLKGDQGP 1304

Query: 215  GPQNYGSGMRPPPNSL--GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272
             P   G+  RP  N +   P +PG+   PG   P   P SA              G PG 
Sbjct: 1305 -PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP-----------EGEPGL 1352

Query: 273  GGPPGTPIMPSPADSTNSSDNIYTMINPVPPG-----GSRS----NFPMG-PGSDGPMG- 321
             GPPG P +P P     S  +I    +  PPG     G +       P G PG  GP G 
Sbjct: 1353 IGPPGPPGLPGP-----SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1407

Query: 322  ----------GMGGME-PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGT 360
                      G GG +    + G  G+  +DG P   P+ + G   PPGT
Sbjct: 1408 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP--GPDGLQGPPGPPGT 1455



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 87/291 (29%), Positives = 104/291 (35%), Gaps = 27/291 (9%)

Query: 100  PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGG 159
            P L  +P   G  G P  PG F G PG         PP NP     P   P     + G 
Sbjct: 1103 PGLPGLPGTPGAKGQPGLPG-FPGTPGPPGPKGISGPPGNPGLPGEP--GPVGGGGHPGQ 1159

Query: 160  PRPPIRMGNQPPGGVPGT-----QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG- 213
            P PP   G     G+PG      +P  P   +P    G P + G       P   G  G 
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 214  PGPQN----YG----SGMRPPPNSLGPAMPGINMGPG----AGRP-WPNPNSANSIPYSS 260
            PGP+     +G     G   PP S GPA+ G    PG     GRP  P P     +P + 
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNG 1278

Query: 261  SSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNI-YTMINPVPPGGSRSNFPMGPGSDGP 319
               G   G PG  G PG P +           N     +N +         P  PG  GP
Sbjct: 1279 GIKGE-KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1337

Query: 320  MGGMGGMEPHHMNGSLGSGDIDGLPKNSPNN--ISGISNPPGTPRDDGELG 368
             G  G   P    G +G     GLP  S  +  I G + PPG P   G  G
Sbjct: 1338 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1388



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 85/295 (28%), Positives = 103/295 (34%), Gaps = 41/295 (13%)

Query: 99  SPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-------F 151
           S ++ ++P   G PG P PPG  QG PG    P    PP  P  +MGP   P        
Sbjct: 160 SIIMSSLPGPKGNPGYPGPPG-IQGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGN 217

Query: 152 MSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGP 211
           M   + G        G Q P G PG        +D   Q+G   + G      PP   GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 212 MG-PGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 269
            G PG +    G +  P   G P   G N  PG             IP     PG Y G 
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------IPGLPGDPG-YPGE 323

Query: 270 P---------GGGGPPGTP--IMPSPADSTNSSDNIYTMINPVPPGGSRSNFP---MGPG 315
           P         G  GPPG P  ++P P       +     +  +P       FP     PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 316 SDGPMGG--MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             GP G   MG   P    G  G    +G P  S     G+   PG P   G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG 438



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 85/297 (28%), Positives = 103/297 (34%), Gaps = 30/297 (10%)

Query: 94  AAAAPSPVLGNIPPNDGMPGGPIPPGF-FQGPPG--SQPSPHAQPPPHNPSSMMGPHSQP 150
           AA    P     P   G  G   PPG    GPPG   QP     P P  P+   GPH  P
Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA---GPHIPP 446

Query: 151 FMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMD------------PTRQQGHPNMGG 198
                  G P PP   G+    G+ G Q +  +  D            P  Q G P + G
Sbjct: 447 SDEICEPGPPGPP---GSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 199 SMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIP 257
               +  P   G  G        G+   P + G P  PG    PG    +P         
Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563

Query: 258 YSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNS---SDNIYTMINPVPPGGSRSNFPMGP 314
            S  +PG   G PG  G  G P +P P                 NP  PG   +  PMGP
Sbjct: 564 GSPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP 622

Query: 315 GSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNI---SGISNPPGTPRDDGELG 368
              GP G +G      + G+ G   I G PK  P       G    PG P  DG++G
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGIPG-PKGDPGQTITQPGKPGLPGNPGRDGDVG 678



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 80/268 (29%), Positives = 102/268 (38%), Gaps = 47/268 (17%)

Query: 110 GMPGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMG 167
           G+PG P P    +GPPG   Q      P P  P  + GP   P   P   G P  P   G
Sbjct: 60  GLPGFPGP----EGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF-PGTPGLPGMPGHDG 114

Query: 168 NQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 227
              P G+PG             ++G P   G      PP   GP G        GM+  P
Sbjct: 115 APGPQGIPGCN-------GTKGERGFPGSPGFPGLQGPP---GPPGI------PGMKGEP 158

Query: 228 NSL-GPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTY--VGPPGGGGPPGTPIMPSP 284
            S+   ++PG    PG    +P P     +P  +  PG     GPPG  GPPG P +P P
Sbjct: 159 GSIIMSSLPGPKGNPG----YPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGP 214

Query: 285 ADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGM--EPHHMNGSLGSGDIDG 342
             +          +N   P G +       G  GP G  G +  +   ++     GD  G
Sbjct: 215 KGNMG--------LNFQGPKGEKGE----QGLQGPPGPPGQISEQKRPIDVEFQKGD-QG 261

Query: 343 LP-KNSPNNISGISNPPGTP-RDDGELG 368
           LP    P    GI  PPG P  + GE G
Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGEKGEKG 289



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 59/189 (31%), Positives = 70/189 (37%), Gaps = 30/189 (15%)

Query: 191 QGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLG----PAMPGINMGPG 242
           +GHP + G      PP   G  G    PGP     G+R PP   G    P +PG+    G
Sbjct: 56  EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPG-PKGIRGPPGLPGFPGTPGLPGMPGHDG 114

Query: 243 AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 302
           A  P   P   N        PG+  G PG  GPPG P +P       S   I     P P
Sbjct: 115 APGPQGIPG-CNGTKGERGFPGS-PGFPGLQGPPGPPGIPGMKGEPGS---IIMSSLPGP 169

Query: 303 PGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 362
            G         PG  GP G  G   P  + G +G           P  + G   PPG P 
Sbjct: 170 KGN--------PGYPGPPGIQGLPGPTGIPGPIGPP--------GPPGLMGPPGPPGLPG 213

Query: 363 DDGELGGNF 371
             G +G NF
Sbjct: 214 PKGNMGLNF 222



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 39/124 (31%), Positives = 44/124 (35%), Gaps = 10/124 (8%)

Query: 268 GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRS-----NFPMGPGSDGPM 320
           G PG  G PG P  P P               P PPG  G R       FP  PG  G  
Sbjct: 51  GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMP 110

Query: 321 GGMGGMEPHHMNGSLGSGDIDGLPKNSPN--NISGISNPPGTPRDDGELGGNFLHSFQND 378
           G  G   P  + G  G+    G P  SP    + G   PPG P   GE G   + S    
Sbjct: 111 GHDGAPGPQGIPGCNGTKGERGFP-GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP 169

Query: 379 NYSP 382
             +P
Sbjct: 170 KGNP 173


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 88/271 (32%), Positives = 104/271 (38%), Gaps = 48/271 (17%)

Query: 106 PPNDGMPGGPIPPGFFQGPPG-SQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPI 164
           PP    P GP  P  F G PG  +P  H QP P  P          F     AG P  P 
Sbjct: 81  PPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPG--------FSRMGKAGPPGLPG 132

Query: 165 RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGM 223
           ++G   P G PG              +G P + G      PP   GP G PGP    SG+
Sbjct: 133 KVG---PPGQPGL-------------RGEPGIRGDQGLRGPP---GPPGLPGP----SGI 169

Query: 224 RPP--PNSLG-PAMPGINMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP 279
             P  P + G P  PG    PG  G P P  +           PG   G PG GG PG P
Sbjct: 170 TIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPG-LPGAPGQGGAPGPP 228

Query: 280 IMPSPAD-STNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGS 337
            +P PA       D +     P  PG    + P G PG  G  G +G   P  ++G +G 
Sbjct: 229 GLPGPAGLGKPGLDGL-----PGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG-VGV 282

Query: 338 GDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
               GLP   P   SG    PGT    G +G
Sbjct: 283 PGAAGLP--GPQGPSGAKGEPGTRGPPGLIG 311



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 88/278 (31%), Positives = 106/278 (38%), Gaps = 51/278 (18%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPH--SQPFM--S 153
           P P    IP   G  G P PPG FQG PG    P  +P P     + G +   QP +  +
Sbjct: 164 PGPSGITIPGKPGAQGVPGPPG-FQGEPG----PQGEPGPPGDRGLKGDNGVGQPGLPGA 218

Query: 154 PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG 213
           P   G P PP         G+PG   L    +D     G P   G      PP   GP G
Sbjct: 219 PGQGGAPGPP---------GLPGPAGLGKPGLD-----GLPGAPGDKGESGPPGVPGPRG 264

Query: 214 -PGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272
            PG      G + PP   G  +PG      AG P P   S      +   PGT  GPPG 
Sbjct: 265 EPG----AVGPKGPPGVDGVGVPG-----AAGLPGPQGPSG-----AKGEPGTR-GPPGL 309

Query: 273 GGPP--GTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHH 330
            GP   G P +P P      +     + +   PG         PG  GP  G+GG  P  
Sbjct: 310 IGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGE-----PGEQGPQ-GLGG--PPG 361

Query: 331 MNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           + GS G     G P   P   +G   PPG P   G+ G
Sbjct: 362 LPGSAGLPGRRGPP--GPKGEAGPGGPPGVPGIRGDQG 397



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 87/309 (28%), Positives = 111/309 (35%), Gaps = 58/309 (18%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMS---- 153
           P P     P  DG+PG P   G   GPPG  P P  +P        +GP   P +     
Sbjct: 231 PGPAGLGKPGLDGLPGAPGDKGE-SGPPGV-PGPRGEP------GAVGPKGPPGVDGVGV 282

Query: 154 PRYAGGPRPPIRMGNQ-------PPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPP 206
           P  AG P P    G +       PPG +  T   +P    P   +G   + G +     P
Sbjct: 283 PGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEP 342

Query: 207 RGMGPMGP-GPQNYGS-----------GMRPPPNSLG-------PAMPGI--NMGPG--A 243
              G  G  GPQ  G            G R PP   G       P +PGI  + GP   A
Sbjct: 343 GEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA 402

Query: 244 GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPP 303
           G+P         +P     PG + GPPG  GP G P           +  +    +   P
Sbjct: 403 GKP--------GVPGERGLPGAH-GPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLP 453

Query: 304 GGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP---KNSPNNISGISNPPG 359
           G      P G PG  GP G +G   P  + G  G   + G P   +      +G + PPG
Sbjct: 454 GQPGLRGPSGIPGLQGPAGPIG---PQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPG 510

Query: 360 TPRDDGELG 368
            P   G  G
Sbjct: 511 VPGSPGITG 519



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 74/273 (27%), Positives = 90/273 (32%), Gaps = 61/273 (22%)

Query: 106 PPNDGMPGGPIPPGFFQGPPG--------SQPSPHAQPPPHNPSSMMGPHSQPFMSPRYA 157
           P   GMPG P P G  +GP G         +P    +P    P  + GP   P  S    
Sbjct: 312 PTGYGMPGLPGPKGD-RGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPG-SAGLP 369

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP--- 214
           G   PP   G   PGG PG  P +     P+   G P + G           GP GP   
Sbjct: 370 GRRGPPGPKGEAGPGGPPGV-PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGE 428

Query: 215 --------GPQNYGS----------------------GMRPPPNSLGP-------AMPGI 237
                   GP   G+                      G++ P   +GP         PG+
Sbjct: 429 PGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGL 488

Query: 238 NMGPGAGRPW-PNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYT 296
              PG GR   P        P    SPG   GPPG  GPPG P  P   D T        
Sbjct: 489 PGPPGEGRAGEPGTAGPTGPPGVPGSPGI-TGPPGPPGPPGPPGAPGAFDETG------- 540

Query: 297 MINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPH 329
           +     P G      +G G   P  G+G +  H
Sbjct: 541 IAGLHLPNGGVEGAVLGKGGK-PQFGLGELSAH 572



 Score = 35.4 bits (80), Expect = 0.088
 Identities = 31/102 (30%), Positives = 34/102 (33%), Gaps = 6/102 (5%)

Query: 267 VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGM 326
           VGPP   G      MP P    +          P PPG      P GP       GMG  
Sbjct: 52  VGPPFREGKGQYLEMPLPLLPMDLKGE------PGPPGKPGPRGPPGPPGFPGKPGMGKP 105

Query: 327 EPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             H   G  G      + K  P  + G   PPG P   GE G
Sbjct: 106 GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPG 147



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 24/72 (33%), Positives = 27/72 (37%), Gaps = 16/72 (22%)

Query: 105 IPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPI 164
           +P   G PG P PPG  +G  G   +     PP  P            SP   G P PP 
Sbjct: 479 LPGLKGEPGLPGPPG--EGRAGEPGTAGPTGPPGVPG-----------SPGITGPPGPP- 524

Query: 165 RMGNQPPGGVPG 176
             G   P G PG
Sbjct: 525 --GPPGPPGAPG 534


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 86/284 (30%), Positives = 98/284 (34%), Gaps = 63/284 (22%)

Query: 106 PPNDGMPGGPIPPGF--------FQGPPGS--QPSPHAQPPPHNPSSMMGPHSQPFMSPR 155
           P   G PG P  PG          +GP G    P    +  P  P   MGP     + PR
Sbjct: 284 PGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGP-----LGPR 338

Query: 156 YAGGPRPPIRMGNQPPGGVPGTQ-----PLLPNSMDPTR---QQGHPNMGGSMQRMNPPR 207
              G R     G   P G PG +     P  P  M P       G P   G      P  
Sbjct: 339 GMPGER-----GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTG 393

Query: 208 GMGPMGPGPQNYGSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTY 266
             GP GP  Q   +G   P  S G P   G +  PGA  P             + SPGT 
Sbjct: 394 ARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGP-------------TGSPGTS 440

Query: 267 VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRS--NFPMGPGSDGPMGGMG 324
            GPPG  GPPG+   P P  ST              P G R     P  PG  G  G  G
Sbjct: 441 -GPPGSAGPPGS---PGPQGSTG-------------PQGIRGQPGDPGVPGFKGEAGPKG 483

Query: 325 GMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
              PH + G +G    +G  K  P    G   PPG   + G  G
Sbjct: 484 EPGPHGIQGPIGPPGEEG--KRGPRGDPGTVGPPGPVGERGAPG 525



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 80/269 (29%), Positives = 101/269 (37%), Gaps = 38/269 (14%)

Query: 112 PGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPP 171
           P GP+      G  G+  +P A+ P  +P +  GP       P  AG P  P   G+  P
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTS-GP-------PGSAGPPGSPGPQGSTGP 460

Query: 172 GGVPGT--QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNS 229
            G+ G    P +P        +G P   G    + PP   G  GP       G   PP  
Sbjct: 461 QGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGD---PGTVGPPGP 517

Query: 230 LGP-AMPGINMGPGA-GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADS 287
           +G    PG    PG+ G P P        P  SS P    G PG  G PG   +P     
Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPG---LPGARGL 574

Query: 288 TNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLG-------SGD 339
           T          NP   G      P+G PG DG  G  G +      GS+G       SGD
Sbjct: 575 TG---------NPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGD 625

Query: 340 IDGLPKNSPNNISGISNPPGTPRDDGELG 368
             G P  + N  +G+    G P  DGE+G
Sbjct: 626 -PGKPGEAGN--AGVPGQRGAPGKDGEVG 651



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 81/286 (28%), Positives = 104/286 (36%), Gaps = 51/286 (17%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
           G PG   PPG  QGP G +  P  +P P  P  + G   +P + P   G P PP    + 
Sbjct: 129 GRPGPAGPPGS-QGPRGER-GPKGRPGPRGPQGIDG---EPGV-PGQPGAPGPPGHPSHP 182

Query: 170 PPGGVP----------------GTQP-LLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPM 212
            P G+                 G+Q  L+P S+ P   +G   + G         G GP 
Sbjct: 183 GPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQ------GGAGPT 236

Query: 213 GPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--YVGPP 270
           GP  +    G   P  S GP  P            P     +  P  + +PG   + G P
Sbjct: 237 GPPGEPGDPGPMGPIGSRGPEGP------------PGKPGEDGEPGRNGNPGEVGFAGSP 284

Query: 271 GGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP-GSDGPMG--GM---- 323
           G  G PG P +P                    PG      P GP G+ GP+G  GM    
Sbjct: 285 GARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGER 344

Query: 324 GGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPGTPRDDGELG 368
           G + P    G  G+  + G P    P  I G S  PG P   GE G
Sbjct: 345 GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 90/313 (28%), Positives = 113/313 (36%), Gaps = 55/313 (17%)

Query: 100  PVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMG-PHSQPFMSPRYAG 158
            P +  +P   GM GG  P     GP GS P P   P    P  + G P  +         
Sbjct: 722  PGITGLPGEKGMAGGHGP----DGPKGS-PGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776

Query: 159  GPRPPI-------RMGNQPPGGVPGTQPL-LPNSMDPTRQQGHPNMGGSMQRMNPPRGMG 210
            G R  I         GN    G+PG  PL  P    PT ++G P   G +    PP   G
Sbjct: 777  GDRGGIGEKGAEGTAGNDGARGLPG--PLGPPGPAGPTGEKGEPGPRGLV---GPPGSRG 831

Query: 211  PMGPGPQNYGSGMRPPPNSLGP-AMPGINMGPG-------AGRPWPN-------PNSANS 255
              G   +N  +G        GP   PG+   PG       AG P P        P+  N 
Sbjct: 832  NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNG 891

Query: 256  IPYSSSSPGTYVGPPGGGGPPGTPIM---PSPADSTNSSDNIYTMINPVPPG-----GSR 307
            +P      GT  GPPG  G PG+      P PA +   +  +       PPG     GS 
Sbjct: 892  VPGLKGGRGTQ-GPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSH 950

Query: 308  SNF--------PMGPGSDGPMG--GMGGME-PHHMNGSLGSGDIDGLP-KNSPNNISGIS 355
                       P GPG  G  G  G  G + P    G+ G   I G+P +     + G+ 
Sbjct: 951  GRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLP 1010

Query: 356  NPPGTPRDDGELG 368
             P GTP   G  G
Sbjct: 1011 GPAGTPGKVGPTG 1023



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 79/280 (28%), Positives = 100/280 (35%), Gaps = 58/280 (20%)

Query: 106 PPNDGMPG-----GPIPPGFFQGPPGSQPSPHAQPPPHNPSS--------MMGPHSQ--P 150
           P +DG+PG     G   P    GP GSQ  P     P  P +        + GP  +  P
Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGP 589

Query: 151 FMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRG-- 208
             +P   G P PP  +G +   G  G      +S DP +     N G   QR  P +   
Sbjct: 590 LGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGE 649

Query: 209 MGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVG 268
           +GP GP               +GP  PG+    G   P P P     +P          G
Sbjct: 650 VGPSGP---------------VGP--PGLAGERGEQGP-PGPTGFQGLPGPP-------G 684

Query: 269 PPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEP 328
           PPG GG PG   +P    +          + P+ P G R N    PG  G  G  G    
Sbjct: 685 PPGEGGKPGDQGVPGDPGA----------VGPLGPRGERGN----PGERGEPGITGLPGE 730

Query: 329 HHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             M G  G     G P   P+   G + PPG     GE G
Sbjct: 731 KGMAGGHGPDGPKGSP--GPSGTPGDTGPPGLQGMPGERG 768



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 71/264 (26%), Positives = 89/264 (33%), Gaps = 31/264 (11%)

Query: 112  PGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPFMS--PRYAGGPRPPIRMG 167
            P GP+     +GPPG    P  H +     P+   GP   P     P   G P P    G
Sbjct: 928  PAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPA---GPPGGPGDKGDPGEDGQPGPD---G 981

Query: 168  NQPPGGVPGTQPL--LPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRP 225
               P G  G + +  +P         G P   G+  ++ P    G  GP       G   
Sbjct: 982  PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGP------PGPVG 1035

Query: 226  PPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP-IMPSP 284
            PP S GP       GP      P  + A         PG   G PG  G PGTP  + +P
Sbjct: 1036 PPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP-AGLPGSQGAPGTPGPVGAP 1094

Query: 285  ADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP 344
             D+    D       P+ P G      + PG  GP G  G        G  G     GL 
Sbjct: 1095 GDAGQRGDP--GSRGPIGPPGRAGKRGL-PGPQGPRGDKGDHGDRGDRGQKGHRGFTGL- 1150

Query: 345  KNSPNNISGISNPPGTPRDDGELG 368
                    G+  PPG   + G  G
Sbjct: 1151 -------QGLPGPPGPNGEQGSAG 1167



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 81/281 (28%), Positives = 95/281 (33%), Gaps = 27/281 (9%)

Query: 106 PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAG--GPR 161
           P   G PG P PPG     GP G      AQ    +  S +G  SQ  + P   G  GPR
Sbjct: 164 PGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLG--SQVGLMPGSVGPVGPR 221

Query: 162 PPI----RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQ 217
            P     + G   P G PG +P  P  M P   +G     G       P   G  G    
Sbjct: 222 GPQGLQGQQGGAGPTGPPG-EPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGF 280

Query: 218 NYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPG 277
               G R  P +  P +PG+  G    +    P      P S    G   GP G  GP G
Sbjct: 281 AGSPGARGFPGA--PGLPGLK-GHRGHKGLEGPKGEVGAPGSKGEAGP-TGPMGAMGPLG 336

Query: 278 TPIMPSP--------ADSTNSSDNIYTMINPVPPGG--SRSNFPMGPGSDGPMGGMGGME 327
              MP          A     +  +     P+ P G    S FP  PG  G  G  G   
Sbjct: 337 PRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARG 396

Query: 328 PHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
           P    G  G     G P  SP  + G     GTP   G  G
Sbjct: 397 PEGPQGQRGETGPPG-PVGSP-GLPGAIGTDGTPGAKGPTG 435



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 58/187 (31%), Positives = 71/187 (37%), Gaps = 26/187 (13%)

Query: 108  NDGMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGP-RPPI 164
            NDG PG  G +     +G PG    P +Q  P  P  +  P          + GP  PP 
Sbjct: 1054 NDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPG 1113

Query: 165  RMGNQPPGGVPGTQPLLPNSMD-----PTRQQGHPNMGGSMQRMNPPRGMGPMG----PG 215
            R G +   G+PG Q    +  D        Q+GH    G      PP   G  G    PG
Sbjct: 1114 RAGKR---GLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPG 1170

Query: 216  PQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGP 275
            P     G R PP  +GP+  G    PG   P   P    S+  +        GPPG  GP
Sbjct: 1171 P----FGPRGPPGPVGPS--GKEGNPGPLGPIGPPGVRGSVGEAGPE-----GPPGEPGP 1219

Query: 276  PGTPIMP 282
            PG P  P
Sbjct: 1220 PGPPGPP 1226



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 52/183 (28%), Positives = 63/183 (34%), Gaps = 17/183 (9%)

Query: 192 GHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPN 251
           G+ N G   +      G+ P+  G +    G   PP S GP       G    +  P P 
Sbjct: 103 GNTNFGRGRKGQKGEPGLVPVVTGIRGR-PGPAGPPGSQGPR------GERGPKGRPGPR 155

Query: 252 SANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP 311
               I      PG     PG  GPPG P  P P   +        M       G  S   
Sbjct: 156 GPQGIDGEPGVPGQ----PGAPGPPGHPSHPGPDGLSRPFSA--QMAGLDEKSGLGSQVG 209

Query: 312 MGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKN----SPNNISGISNPPGTPRDDGEL 367
           + PGS GP+G  G        G  G     G P +     P    G   PPG P +DGE 
Sbjct: 210 LMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEP 269

Query: 368 GGN 370
           G N
Sbjct: 270 GRN 272


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 69/229 (30%), Positives = 92/229 (40%), Gaps = 27/229 (11%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYA 157
           P P++  +PP   +P    PP     PPG  P P   P    PS   GP   P  +P   
Sbjct: 234 PPPLMNGLPPRPPLPESLPPP-----PPGGLPLPPMPPTGPAPSGPPGPPQLPPPAP--- 285

Query: 158 GGPRPPIRMGNQPPGGV----PGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPR-GMGPM 212
            G  PP  + + P  GV    PG  P  P  + P     HP   G    ++PP  G+ P 
Sbjct: 286 -GVHPPAPVVHPPASGVHPPAPGVHPPAPG-VHPPAPGVHPPTSG----VHPPAPGVHPP 339

Query: 213 GPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIP-YSSSSPGTYVGPPG 271
            PG      G+ PP   + P  PG++  P AG     P    + P     +PG  V PP 
Sbjct: 340 APGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPG--VHPPA 397

Query: 272 GGGPPGTP-IMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGP 319
            G  P  P + P P     S+  ++    P PPG   SN  + P +  P
Sbjct: 398 PGMHPQAPGVHPQPPGVHPSAPGVH----PQPPGVHPSNPGVHPPTPMP 442



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 56/202 (27%), Positives = 76/202 (37%), Gaps = 18/202 (8%)

Query: 134 QPPPHNPSSMMGPHSQPFMSPRYAGG--PRPPI--RMGNQPPGGVPGTQPLLPNSMDPTR 189
           + PP  PS   GP       P    G  PRPP+   +   PPGG+P   P+ P    P+ 
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLP-LPPMPPTGPAPSG 273

Query: 190 QQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPN 249
             G P      Q   P  G+ P  P      SG+ PP   + P  PG++  P A    P 
Sbjct: 274 PPGPP------QLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVH--PPAPGVHPP 325

Query: 250 PNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG---GS 306
            +  +        P   V PP  G  P  P +  PA   +   +    ++P  PG    +
Sbjct: 326 TSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPS--AGVHPQAPGVHPAA 383

Query: 307 RSNFPMGPGSDGPMGGMGGMEP 328
            +  P  PG   P  GM    P
Sbjct: 384 PAVHPQAPGVHPPAPGMHPQAP 405


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 88/303 (29%), Positives = 109/303 (35%), Gaps = 54/303 (17%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
           G+  GP+ P   +GPPG   +P  Q    NP     P     M PR  G P PP + G+ 
Sbjct: 197 GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR--GPPGPPGKPGDD 254

Query: 170 -------------PPG-----GVPGTQPLLPN--------SMDPTR-QQGHPNMGGSMQR 202
                        PPG     G PGT P LP          +D  + + G P + G    
Sbjct: 255 GEAGKPGKAGERGPPGPQGARGFPGT-PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313

Query: 203 MNPPRGMGPMGP----------GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNS 252
                  GPMGP          GP    +G R      GPA P   +GP  G  +P    
Sbjct: 314 PGENGSPGPMGPRGLPGERGRTGPAG-AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG 372

Query: 253 ANSIPYSSSSPGTYVGPPGGGGP---PGTPIMPSPADSTNS--SDNIYTMINP--VPPGG 305
           A       + P    GP G  GP   PGTP  P PA ++ +  +D I         P   
Sbjct: 373 AK----GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 428

Query: 306 SRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
               FP   G  GP G  G + P    G  G     G  +  P    G + P G P   G
Sbjct: 429 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG--EQGPKGEPGPAGPQGAPGPAG 486

Query: 366 ELG 368
           E G
Sbjct: 487 EEG 489



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 84/303 (27%), Positives = 98/303 (32%), Gaps = 56/303 (18%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPR 155
           P+   GN P  DG+PG     G     G PG  P P   P P   +  +GP  Q      
Sbjct: 403 PAGASGN-PGTDGIPGAKGSAGAPGIAGAPGF-PGPRGPPGPQGATGPLGPKGQ------ 454

Query: 156 YAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNP---PRGMGPM 212
             G P      G Q P G PG          P   QG P   G   +      P G+GP+
Sbjct: 455 -TGEPGIAGFKGEQGPKGEPG----------PAGPQGAPGPAGEEGKRGARGEPGGVGPI 503

Query: 213 GPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YV 267
           GP  +    G R  P   G A P    G         P  AN  P     PG        
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 268 GPPGGGGP---------PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG----- 313
           G PG  GP         PG    P P     +      M  P P G +      G     
Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 623

Query: 314 --------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
                   PG DG  G  G   P    G  G     G P   P+   G+  PPG P + G
Sbjct: 624 GAPGLRGLPGKDGETGAAG---PPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGG 678

Query: 366 ELG 368
           + G
Sbjct: 679 KPG 681



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 86/286 (30%), Positives = 97/286 (33%), Gaps = 43/286 (15%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIR 165
           P N G PG P PP    GPPG   +  AQ          G        P    GPR P  
Sbjct: 158 PGNPGPPGPPGPP----GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP-- 211

Query: 166 MGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYG---- 220
                P G PG Q    N  +P    G P + G M    PP   GP G PG         
Sbjct: 212 ---PGPAGAPGPQGFQGNPGEP----GEPGVSGPMGPRGPP---GPPGKPGDDGEAGKPG 261

Query: 221 -SGMRPPPNSLG----PAMPGINMGPGAGRPWPNPNSAN------SIPYSSSSPGTYVGP 269
            +G R PP   G    P  PG+  G    R +P  + A        +   S SPG   G 
Sbjct: 262 KAGERGPPGPQGARGFPGTPGL-PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN-GS 319

Query: 270 PGGGGPPGTP-----IMPSPADSTNSSDNIYTMINPVPPGGSRS--NFPMGPGSDGPMGG 322
           PG  GP G P       P+ A     +D       P  P G      FP  PG+ G  G 
Sbjct: 320 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379

Query: 323 MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
            G   P    G  G     G P   P   SG     G P   G  G
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSP--GPAGASGNPGTDGIPGAKGSAG 423



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 85/307 (27%), Positives = 98/307 (31%), Gaps = 61/307 (19%)

Query: 106  PPNDGMPGGPIPPGFF-----------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSP 154
            P ++G PG P PPG              GPPG    P  Q P   P     P       P
Sbjct: 908  PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD---GP 964

Query: 155  RYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
              A GP  P  +  Q   G+ G    LP         G P   G   +   P   G  GP
Sbjct: 965  SGAEGPPGPQGLAGQR--GIVG----LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGP 1018

Query: 215  GPQNYGSGMRPPPNSLGPA-MPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGG 273
                   G   PP   GPA  PG    PGA  P P  + A  +       G  VG PG  
Sbjct: 1019 ------PGPVGPPGLTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGA-VGAPGAP 1070

Query: 274  GPPGTPIMPSPADSTNSSDNIYTM--INPVPPGGSRS-NFPMGPGSD------------- 317
            GPPG+P    P               + P  P G+R    P GP  D             
Sbjct: 1071 GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1130

Query: 318  ---------------GPMGGMGGMEPHHMNGSLGS-GDIDGLPKNSPNNISGISNPPGTP 361
                           GP G  G   P   +G  G  G +    K+  N I G   PPG  
Sbjct: 1131 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1190

Query: 362  RDDGELG 368
               GE G
Sbjct: 1191 GRSGETG 1197



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 85/311 (27%), Positives = 96/311 (30%), Gaps = 60/311 (19%)

Query: 102  LGNIPPNDGMPG--GPIPPGFFQGPPGSQ-----------------------PSPHAQPP 136
            L   P  DG  G  GP  P   QGPPG Q                         P   P 
Sbjct: 721  LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780

Query: 137  PHNPSSMMGPHSQPFMSPRYAGGPR----PPIRMGNQPPGGVPG----TQPLLPNSM-DP 187
                  + GP   P   P  A G +    PP   G+    G PG    T P  P     P
Sbjct: 781  KDGGRGLTGPIGPP--GPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838

Query: 188  TRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPW 247
                G P   G           G   PGPQ        P  + GP  P    GP   R  
Sbjct: 839  PGADGQPGAKGEQGEAGQKGDAG--APGPQG-------PSGAPGPQGPTGVTGPKGARGA 889

Query: 248  PNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSR 307
              P  A   P ++      VGPPG  G PG P  P P+              P   G   
Sbjct: 890  QGPPGATGFPGAAGR----VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPG 945

Query: 308  SNFPMG-------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPG 359
               P G       PG DGP G  G   P  + G  G   I GLP +       G+  P G
Sbjct: 946  LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG---IVGLPGQRGERGFPGLPGPSG 1002

Query: 360  TPRDDGELGGN 370
             P   G  G +
Sbjct: 1003 EPGKQGAPGAS 1013



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 88/315 (27%), Positives = 104/315 (33%), Gaps = 67/315 (21%)

Query: 110  GMPG-----GPIPPGFFQGPPGSQPSPHAQ--------------PPPHNPSSMMGPHSQP 150
            G PG     GP  P  F GPPG+   P A+              P P  PS   GP    
Sbjct: 819  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878

Query: 151  FMS-----------------PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGH 193
             ++                 P  AG   PP   GN  P G PG     P+  D  +  G 
Sbjct: 879  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG-----PSGKDGPK--GA 931

Query: 194  PNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMP-------GINMGPG--AG 244
                G   R   P   GP GP  +    G   P  + GP  P       GI   PG    
Sbjct: 932  RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 991

Query: 245  RPWPNPNSANSIPYSSSSPGTY--------VGPPGGGGPPGTPIMP-SP-ADSTNSSDNI 294
            R +P     +  P    +PG          VGPPG  GP G P    SP AD     D  
Sbjct: 992  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051

Query: 295  YTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG-LPKNSPNNISG 353
              +       G+       PG+ GP G  G   P    G  G     G +  + P    G
Sbjct: 1052 AGVKGDRGETGAVG----APGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1107

Query: 354  ISNPPGTPRDDGELG 368
            I  P G   D GE G
Sbjct: 1108 IQGPQGPRGDKGEAG 1122



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 84/309 (27%), Positives = 106/309 (34%), Gaps = 79/309 (25%)

Query: 110 GMPGG--PIPPGFFQGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQPFMSPRYAGG 159
           G PGG  PI P   +G PG++          P   P    PS + GP           G 
Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK----------GA 544

Query: 160 PRPPIRMGNQPPGGVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG---- 213
              P R G     G+PG + L   P    P  + G     G   R  PP   G  G    
Sbjct: 545 NGDPGRPGEP---GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 601

Query: 214 ---PGPQNYGSGMRPPPNSLG----PAMPGINMGPG-------AGRPWPNPNSANSIPYS 259
              PGP+    G    P   G    P  PG+   PG       AG P P   +       
Sbjct: 602 MGFPGPK----GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 657

Query: 260 SSSPGTYVG------PPGGGGPPGTPIMPSPADSTNSSDNIYTMINP----------VPP 303
           +  P  + G      PPG GG PG   +P  A +         ++ P            P
Sbjct: 658 APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG-------LVGPRGERGFPGERGSP 710

Query: 304 GGSRSNFPMG----PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPG 359
           G      P G    PG+DGP G  G   P    G+ G   + G+P       +GI+ P G
Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMP--GERGAAGIAGPKG 765

Query: 360 TPRDDGELG 368
              D GE G
Sbjct: 766 DRGDVGEKG 774



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 79/285 (27%), Positives = 98/285 (34%), Gaps = 67/285 (23%)

Query: 106  PPNDGMPGGPIPPGF--------------FQGPPGSQPSPHAQPPPHNPSSMMGPH---- 147
            P  +G PG   PPG                 G PG+ P P   P P  P+   G      
Sbjct: 1034 PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-PGPPGSPGPAGPTGKQGDRGEAG 1092

Query: 148  SQPFMSPRYAGGPR----PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRM 203
            +Q  M P    G R    P    G++   G PG + L          +GH    G     
Sbjct: 1093 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL----------KGHRGFTGLQGLP 1142

Query: 204  NPPRGMGPMGPGPQNYGSGMRPPPNSLGPA-MPGINMGPGA-GRPWPNPNSANSIPYSSS 261
             PP   G  G       SG R PP  +GP+   G N  PG  G P P   S  + P    
Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGP---- 1198

Query: 262  SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP-MGPGSDGPM 320
                  GPPG  GPPG P                    P  PG   S F  +GP   GP 
Sbjct: 1199 -----AGPPGNPGPPGPP-------------------GPPGPGIDMSAFAGLGPREKGP- 1233

Query: 321  GGMGGMEPHHMNGSLGSGD--IDGLPKNSPNNISGISNPPGTPRD 363
              +  M      G L   D  +D   K+  N I  I +P G+ ++
Sbjct: 1234 DPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKN 1278



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 74/257 (28%), Positives = 88/257 (34%), Gaps = 35/257 (13%)

Query: 128 QPSPHAQP-PPHNPSSMMGPHSQPF-MSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSM 185
           QP P  Q   P +   ++GP   P    P    GPR     G++   G PG         
Sbjct: 99  QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD--RGDKGEKGAPG--------- 147

Query: 186 DPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPP-PNSLGPAMPGINMGP--- 241
            P  + G P   G+     PP   GP G G  N+ + M        G A  G+  GP   
Sbjct: 148 -PRGRDGEPGTPGNPGPPGPPGPPGPPGLG-GNFAAQMAGGFDEKAGGAQLGVMQGPMGP 205

Query: 242 --------GAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDN 293
                    AG P P     N  P     PG   GP G  GPPG P  P   D       
Sbjct: 206 MGPRGPPGPAGAPGPQGFQGN--PGEPGEPGV-SGPMGPRGPPGPPGKPGD-DGEAGKPG 261

Query: 294 IYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSP--NNI 351
                 P  P G+R  FP  PG  G  G  G        G  G+  + G    SP  N  
Sbjct: 262 KAGERGPPGPQGAR-GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG-ESGSPGENGS 319

Query: 352 SGISNPPGTPRDDGELG 368
            G   P G P + G  G
Sbjct: 320 PGPMGPRGLPGERGRTG 336


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 88/303 (29%), Positives = 109/303 (35%), Gaps = 54/303 (17%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
           G+  GP+ P   +GPPG   +P  Q    NP     P     M PR  G P PP + G+ 
Sbjct: 128 GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR--GPPGPPGKPGDD 185

Query: 170 -------------PPG-----GVPGTQPLLPN--------SMDPTR-QQGHPNMGGSMQR 202
                        PPG     G PGT P LP          +D  + + G P + G    
Sbjct: 186 GEAGKPGKAGERGPPGPQGARGFPGT-PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244

Query: 203 MNPPRGMGPMGP----------GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNS 252
                  GPMGP          GP    +G R      GPA P   +GP  G  +P    
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAG-AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG 303

Query: 253 ANSIPYSSSSPGTYVGPPGGGGP---PGTPIMPSPADSTNS--SDNIYTMINP--VPPGG 305
           A       + P    GP G  GP   PGTP  P PA ++ +  +D I         P   
Sbjct: 304 AK----GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 359

Query: 306 SRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
               FP   G  GP G  G + P    G  G     G  +  P    G + P G P   G
Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG--EQGPKGEPGPAGPQGAPGPAG 417

Query: 366 ELG 368
           E G
Sbjct: 418 EEG 420



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 84/303 (27%), Positives = 98/303 (32%), Gaps = 56/303 (18%)

Query: 98  PSPVLGNIPPNDGMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPR 155
           P+   GN P  DG+PG     G     G PG  P P   P P   +  +GP  Q      
Sbjct: 334 PAGASGN-PGTDGIPGAKGSAGAPGIAGAPGF-PGPRGPPGPQGATGPLGPKGQ------ 385

Query: 156 YAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNP---PRGMGPM 212
             G P      G Q P G PG          P   QG P   G   +      P G+GP+
Sbjct: 386 -TGEPGIAGFKGEQGPKGEPG----------PAGPQGAPGPAGEEGKRGARGEPGGVGPI 434

Query: 213 GPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT-----YV 267
           GP  +    G R  P   G A P    G         P  AN  P     PG        
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494

Query: 268 GPPGGGGP---------PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG----- 313
           G PG  GP         PG    P P     +      M  P P G +      G     
Sbjct: 495 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 554

Query: 314 --------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
                   PG DG  G  G   P    G  G     G P   P+   G+  PPG P + G
Sbjct: 555 GAPGLRGLPGKDGETGAAG---PPGPAGPAGERGEQGAP--GPSGFQGLPGPPGPPGEGG 609

Query: 366 ELG 368
           + G
Sbjct: 610 KPG 612



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 86/286 (30%), Positives = 97/286 (33%), Gaps = 43/286 (15%)

Query: 106 PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIR 165
           P N G PG P PP    GPPG   +  AQ          G        P    GPR P  
Sbjct: 89  PGNPGPPGPPGPP----GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP-- 142

Query: 166 MGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYG---- 220
                P G PG Q    N  +P    G P + G M    PP   GP G PG         
Sbjct: 143 ---PGPAGAPGPQGFQGNPGEP----GEPGVSGPMGPRGPP---GPPGKPGDDGEAGKPG 192

Query: 221 -SGMRPPPNSLG----PAMPGINMGPGAGRPWPNPNSAN------SIPYSSSSPGTYVGP 269
            +G R PP   G    P  PG+  G    R +P  + A        +   S SPG   G 
Sbjct: 193 KAGERGPPGPQGARGFPGTPGL-PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN-GS 250

Query: 270 PGGGGPPGTP-----IMPSPADSTNSSDNIYTMINPVPPGGSRS--NFPMGPGSDGPMGG 322
           PG  GP G P       P+ A     +D       P  P G      FP  PG+ G  G 
Sbjct: 251 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310

Query: 323 MGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
            G   P    G  G     G P   P   SG     G P   G  G
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSP--GPAGASGNPGTDGIPGAKGSAG 354



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 85/307 (27%), Positives = 98/307 (31%), Gaps = 61/307 (19%)

Query: 106  PPNDGMPGGPIPPGFF-----------QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSP 154
            P ++G PG P PPG              GPPG    P  Q P   P     P       P
Sbjct: 839  PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD---GP 895

Query: 155  RYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP 214
              A GP  P  +  Q   G+ G    LP         G P   G   +   P   G  GP
Sbjct: 896  SGAEGPPGPQGLAGQR--GIVG----LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGP 949

Query: 215  GPQNYGSGMRPPPNSLGPA-MPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGG 273
                   G   PP   GPA  PG    PGA  P P  + A  +       G  VG PG  
Sbjct: 950  ------PGPVGPPGLTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGA-VGAPGAP 1001

Query: 274  GPPGTPIMPSPADSTNSSDNIYTM--INPVPPGGSRS-NFPMGPGSD------------- 317
            GPPG+P    P               + P  P G+R    P GP  D             
Sbjct: 1002 GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1061

Query: 318  ---------------GPMGGMGGMEPHHMNGSLGS-GDIDGLPKNSPNNISGISNPPGTP 361
                           GP G  G   P   +G  G  G +    K+  N I G   PPG  
Sbjct: 1062 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR 1121

Query: 362  RDDGELG 368
               GE G
Sbjct: 1122 GRSGETG 1128



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 85/311 (27%), Positives = 96/311 (30%), Gaps = 60/311 (19%)

Query: 102 LGNIPPNDGMPG--GPIPPGFFQGPPGSQ-----------------------PSPHAQPP 136
           L   P  DG  G  GP  P   QGPPG Q                         P   P 
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711

Query: 137 PHNPSSMMGPHSQPFMSPRYAGGPR----PPIRMGNQPPGGVPG----TQPLLPNSM-DP 187
                 + GP   P   P  A G +    PP   G+    G PG    T P  P     P
Sbjct: 712 KDGGRGLTGPIGPP--GPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 769

Query: 188 TRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPW 247
               G P   G           G   PGPQ        P  + GP  P    GP   R  
Sbjct: 770 PGADGQPGAKGEQGEAGQKGDAG--APGPQG-------PSGAPGPQGPTGVTGPKGARGA 820

Query: 248 PNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSR 307
             P  A   P ++      VGPPG  G PG P  P P+              P   G   
Sbjct: 821 QGPPGATGFPGAAGR----VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPG 876

Query: 308 SNFPMG-------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNPPG 359
              P G       PG DGP G  G   P  + G  G   I GLP +       G+  P G
Sbjct: 877 LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG---IVGLPGQRGERGFPGLPGPSG 933

Query: 360 TPRDDGELGGN 370
            P   G  G +
Sbjct: 934 EPGKQGAPGAS 944



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 88/315 (27%), Positives = 104/315 (33%), Gaps = 67/315 (21%)

Query: 110  GMPG-----GPIPPGFFQGPPGSQPSPHAQ--------------PPPHNPSSMMGPHSQP 150
            G PG     GP  P  F GPPG+   P A+              P P  PS   GP    
Sbjct: 750  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809

Query: 151  FMS-----------------PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGH 193
             ++                 P  AG   PP   GN  P G PG     P+  D  +  G 
Sbjct: 810  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG-----PSGKDGPK--GA 862

Query: 194  PNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMP-------GINMGPG--AG 244
                G   R   P   GP GP  +    G   P  + GP  P       GI   PG    
Sbjct: 863  RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 922

Query: 245  RPWPNPNSANSIPYSSSSPGTY--------VGPPGGGGPPGTPIMP-SP-ADSTNSSDNI 294
            R +P     +  P    +PG          VGPPG  GP G P    SP AD     D  
Sbjct: 923  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982

Query: 295  YTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDG-LPKNSPNNISG 353
              +       G+       PG+ GP G  G   P    G  G     G +  + P    G
Sbjct: 983  AGVKGDRGETGAVG----APGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1038

Query: 354  ISNPPGTPRDDGELG 368
            I  P G   D GE G
Sbjct: 1039 IQGPQGPRGDKGEAG 1053



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 84/309 (27%), Positives = 106/309 (34%), Gaps = 79/309 (25%)

Query: 110 GMPGG--PIPPGFFQGPPGSQ--------PSPHAQPPPHNPSSMMGPHSQPFMSPRYAGG 159
           G PGG  PI P   +G PG++          P   P    PS + GP           G 
Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK----------GA 475

Query: 160 PRPPIRMGNQPPGGVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG---- 213
              P R G     G+PG + L   P    P  + G     G   R  PP   G  G    
Sbjct: 476 NGDPGRPGEP---GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 532

Query: 214 ---PGPQNYGSGMRPPPNSLG----PAMPGINMGPG-------AGRPWPNPNSANSIPYS 259
              PGP+    G    P   G    P  PG+   PG       AG P P   +       
Sbjct: 533 MGFPGPK----GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 588

Query: 260 SSSPGTYVG------PPGGGGPPGTPIMPSPADSTNSSDNIYTMINP----------VPP 303
           +  P  + G      PPG GG PG   +P  A +         ++ P            P
Sbjct: 589 APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG-------LVGPRGERGFPGERGSP 641

Query: 304 GGSRSNFPMG----PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPG 359
           G      P G    PG+DGP G  G   P    G+ G   + G+P       +GI+ P G
Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMP--GERGAAGIAGPKG 696

Query: 360 TPRDDGELG 368
              D GE G
Sbjct: 697 DRGDVGEKG 705



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 79/285 (27%), Positives = 98/285 (34%), Gaps = 67/285 (23%)

Query: 106  PPNDGMPGGPIPPGF--------------FQGPPGSQPSPHAQPPPHNPSSMMGPH---- 147
            P  +G PG   PPG                 G PG+ P P   P P  P+   G      
Sbjct: 965  PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-PGPPGSPGPAGPTGKQGDRGEAG 1023

Query: 148  SQPFMSPRYAGGPR----PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRM 203
            +Q  M P    G R    P    G++   G PG + L          +GH    G     
Sbjct: 1024 AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL----------KGHRGFTGLQGLP 1073

Query: 204  NPPRGMGPMGPGPQNYGSGMRPPPNSLGPA-MPGINMGPGA-GRPWPNPNSANSIPYSSS 261
             PP   G  G       SG R PP  +GP+   G N  PG  G P P   S  + P    
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGP---- 1129

Query: 262  SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFP-MGPGSDGPM 320
                  GPPG  GPPG P                    P  PG   S F  +GP   GP 
Sbjct: 1130 -----AGPPGNPGPPGPP-------------------GPPGPGIDMSAFAGLGPREKGP- 1164

Query: 321  GGMGGMEPHHMNGSLGSGD--IDGLPKNSPNNISGISNPPGTPRD 363
              +  M      G L   D  +D   K+  N I  I +P G+ ++
Sbjct: 1165 DPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKN 1209



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 76/263 (28%), Positives = 90/263 (34%), Gaps = 35/263 (13%)

Query: 122 QGPPGSQPSPHAQP-PPHNPSSMMGPHSQPF-MSPRYAGGPRPPIRMGNQPPGGVPGTQP 179
           QG    QP P  Q   P +   ++GP   P    P    GPR     G++   G PG   
Sbjct: 24  QGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD--RGDKGEKGAPG--- 78

Query: 180 LLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPP-PNSLGPAMPGIN 238
                  P  + G P   G+     PP   GP G G  N+ + M        G A  G+ 
Sbjct: 79  -------PRGRDGEPGTPGNPGPPGPPGPPGPPGLG-GNFAAQMAGGFDEKAGGAQLGVM 130

Query: 239 MGP-----------GAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADS 287
            GP            AG P P     N  P     PG   GP G  GPPG P  P   D 
Sbjct: 131 QGPMGPMGPRGPPGPAGAPGPQGFQGN--PGEPGEPGV-SGPMGPRGPPGPPGKPGD-DG 186

Query: 288 TNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNS 347
                       P  P G+R  FP  PG  G  G  G        G  G+  + G    S
Sbjct: 187 EAGKPGKAGERGPPGPQGAR-GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG-ESGS 244

Query: 348 P--NNISGISNPPGTPRDDGELG 368
           P  N   G   P G P + G  G
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTG 267


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 85/287 (29%), Positives = 101/287 (35%), Gaps = 43/287 (14%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
           G PG P  PG  QG PG +  P     P       G H     +P  AG P  P  +G  
Sbjct: 356 GDPGLPGEPGL-QGRPG-ELGPQGPTGPPGAKGQEGAHG----APGAAGNPGAPGHVGAP 409

Query: 170 PPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-------PGPQNYGS- 221
            P G PG+    P       + G     G+      P  +GP G       PGP   G  
Sbjct: 410 GPSGPPGSVGA-PGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 468

Query: 222 ---GMRPPPNSLGP-------AMPGINMGPG---------AGRPWPN-PNSANSIPYSSS 261
              G+R  P   GP         PGI   PG         AG P P+ P      P S  
Sbjct: 469 GEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG 528

Query: 262 SPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMG 321
            PG + GP G  G  G   + SP D    + ++     P PPG      P  PG  G  G
Sbjct: 529 LPG-FPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPG-----LPGLPGFKGDKG 582

Query: 322 GMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
             G        G  G     GLP   P  I+G     G    DGE+G
Sbjct: 583 VPGKPGREGTEGKKGEAGPPGLP--GPPGIAGPQGSQGERGADGEVG 627



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 85/277 (30%), Positives = 103/277 (37%), Gaps = 32/277 (11%)

Query: 105 IPPNDGMPGGPIPPGF-----FQGPPGSQPSP--HAQPPPHNPSSMMGPHSQPFMSPRYA 157
           +P   G PG P PPG        GPPG Q SP     P P  PS + G   +     R  
Sbjct: 637 VPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGR-D 695

Query: 158 GGPRPPIRMGNQPPGGVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 215
           G P PP   G     G+PG +     P     T   G P   G    M  P   G  G  
Sbjct: 696 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 755

Query: 216 PQNYGSGMRPPPNSLGPAMPGINMGPGA-GRPWPN--PNSANSIPYSSSSPGT--YVGPP 270
                +G + P    GP  PG N  PG+ G P P+  P    S    + SPG   ++GP 
Sbjct: 756 GDTGPTGPQGPQGPRGP--PGKNGSPGSPGEPGPSGTPGQKGS-KGENGSPGLPGFLGPR 812

Query: 271 GGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPG--GSRSNFPMGPGSDGPMGGMGGMEP 328
           G  G PG   +P                 P  PG  G R + P   G  GP GG G    
Sbjct: 813 GPPGEPGEKGVPGKEGVPG---------KPGEPGFKGERGD-PGIKGDKGPPGGKGQPGD 862

Query: 329 HHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDG 365
             + G  G   + G P+  P   +G   PPG P   G
Sbjct: 863 PGIPGHKGHTGLMG-PQGLPGE-NGPVGPPGPPGQPG 897



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 88/323 (27%), Positives = 117/323 (36%), Gaps = 45/323 (13%)

Query: 99  SPVLGNIPPNDGMPGGPI--PPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRY 156
           +P +   P + G PG  +  PPG   GPPG + SP ++  P  P    GP  +  +S   
Sbjct: 491 APGIPGSPGSRGDPGIGVAGPPGP-SGPPGDKGSPGSRGLPGFPGPQ-GPAGRDGLSSLL 548

Query: 157 AGGPRPPIRMG--NQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMN---PPRGMGP 211
           + G    +     N  P G PG  P LP         G P   G+  +     PP   GP
Sbjct: 549 SPGDINLLAKDVCNDCPPGPPGL-PGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 607

Query: 212 MG-PGPQNYGSGMRPPPNSLG-------PAMPGINMGPGAGRPWPNPNSANSIPYSSSSP 263
            G  GPQ    G R     +G       P +PG  MGP      P P  A+ I  ++  P
Sbjct: 608 PGIAGPQG-SQGERGADGEVGQKGDQGHPGVPGF-MGPPGN---PGPPGADGIAGAAGPP 662

Query: 264 GTY-----VGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG----P 314
           G        GPPG  GP G P +P                 P   G      P G    P
Sbjct: 663 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP 722

Query: 315 GSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-------------KNSPNNISGISNPPGTP 361
           G  G  G  G   P   +G++G    +GLP                P    G +  PG+P
Sbjct: 723 GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 782

Query: 362 RDDGELGGNFLHSFQNDNYSPSM 384
            + G  G       + +N SP +
Sbjct: 783 GEPGPSGTPGQKGSKGENGSPGL 805



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 80/296 (27%), Positives = 100/296 (33%), Gaps = 44/296 (14%)

Query: 110 GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
           G PG P PPG   GP GSQ    A            P    FM P   G P PP   G  
Sbjct: 600 GPPGLPGPPGI-AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP--PGNPGPPGADGIA 656

Query: 170 PPGGVPGTQ--PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 227
              G PG Q  P       P    G P + G   +       GP G   +    G+  P 
Sbjct: 657 GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPE 716

Query: 228 NSLGPAMPGINMGPG-AGRPWPNPNS-ANSIPYSSSSPGTYV--------------GPPG 271
            + GP  PG     G +G P P   S A  +P     PG                 GPPG
Sbjct: 717 GARGP--PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 774

Query: 272 GGGPPGTPIMPSPADS--------TNSSDNIYTMINPVPPGGSRS-----------NFPM 312
             G PG+P  P P+ +         N S  +   + P  P G                P 
Sbjct: 775 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 834

Query: 313 GPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
            PG  G  G  G        G  G     G+P +  +  +G+  P G P ++G +G
Sbjct: 835 EPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH--TGLMGPQGLPGENGPVG 888



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 88/318 (27%), Positives = 109/318 (34%), Gaps = 58/318 (18%)

Query: 106  PPNDGMPGGPIPPGFFQGPPG--SQPSPHAQPPPHNPSSMMGPHSQPFM----------S 153
            P   G PG P P G  +GPPG          P P   S  MG   Q  +           
Sbjct: 704  PGKAGEPGLPGPEGA-RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 762

Query: 154  PRYAGGPR-PPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPM 212
            P+   GPR PP + G+    G PG     P       + G P + G +    PP   G  
Sbjct: 763  PQGPQGPRGPPGKNGSPGSPGEPGPSGT-PGQKGSKGENGSPGLPGFLGPRGPPGEPGEK 821

Query: 213  G-PGPQNYGSGMRPPPNSLGPAMPGI--NMGP--GAGRPW----PNPNSANSIPYSSSSP 263
            G PG +        P        PGI  + GP  G G+P     P       +      P
Sbjct: 822  GVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP 881

Query: 264  GTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMIN----------------PVPPGGSR 307
            G   GP G  GPPG P  P     + S + +  +I                  +PP   +
Sbjct: 882  GEN-GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 940

Query: 308  SN----FPMG-------PGSDGPMG-----GMGGME-PHHMNGSLGSGDIDGLPKNSPNN 350
            S+     P G       PG  GPMG     G GG+E P    G  G     G P      
Sbjct: 941  SSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVG 1000

Query: 351  ISGISNPPGTPRDDGELG 368
            + G   PPG P   GE G
Sbjct: 1001 LRGEMGPPGIPGQPGEPG 1018



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 87/335 (25%), Positives = 115/335 (34%), Gaps = 46/335 (13%)

Query: 70  YCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPN----DGMPGGP-----IPPGF 120
           + AA   +   +  ++A+A    +A  AP     N  P     DG+PG P     I    
Sbjct: 215 FSAALGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQG 274

Query: 121 FQGPPGSQ-----PSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVP 175
             G PG +     P     P         G   +  + P   G        G   P G+P
Sbjct: 275 LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL-PGLKGDRGEKGEAGPAGPPGLP 333

Query: 176 GT------QPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGS--GMRPP 226
           GT       P +P    P  ++G P + G       P  +GP GP GP       G    
Sbjct: 334 GTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGA 393

Query: 227 PNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGT--YVGPPGGGGPPGTPIMPS 283
           P + G P  PG    PG   P   P S  + P    +PG     G  G  G  G+P    
Sbjct: 394 PGAAGNPGAPGHVGAPGPSGP---PGSVGA-PGLRGTPGKDGERGEKGAAGEEGSPGPVG 449

Query: 284 PADSTNSSDNIYTMINPVPPGGSRSNFPM---GPGSDGPMGGMGGMEPHHMNGSLGSGDI 340
           P     +         P PPG  +   P     PG  GP+G  G      + GS GS   
Sbjct: 450 PRGDPGAPGL------PGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGD 503

Query: 341 DGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSF 375
            G+       ++G   P G P D G  G   L  F
Sbjct: 504 PGI------GVAGPPGPSGPPGDKGSPGSRGLPGF 532



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 83/309 (26%), Positives = 106/309 (34%), Gaps = 60/309 (19%)

Query: 105  IPPNDGMPG--------GPIPPGFFQGPPGSQPSPHA--QPPPHNPSSMMGPHSQPFMSP 154
            +P  +G+PG        GP  P   +GPPG   SP +  +P P       G   +   SP
Sbjct: 745  LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG-SP 803

Query: 155  RYAG--GPRPPIRMGNQPPGGVPGTQ--PLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMG 210
               G  GPR P   G     GVPG +  P  P       ++G P + G      PP G G
Sbjct: 804  GLPGFLGPRGP--PGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDK---GPPGGKG 858

Query: 211  PMG----PGPQNYGSGMRPP--PNSLGPAMPGINMG----PGAGRPWPNPNSANSIPYS- 259
              G    PG + +   M P   P   GP  P    G    PG     P+  +   +    
Sbjct: 859  QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 918

Query: 260  -------------SSSPGTYV----GPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 302
                         +  P  Y+    G PG  GPPG   +P  A           M  P  
Sbjct: 919  LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP---------MGEPGR 969

Query: 303  PGGSRSNFPMGP-GSDGPMGGMG--GMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPG 359
            PG      P GP G  G  G  G  G     + G +G   I G P        G+   PG
Sbjct: 970  PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPG 1029

Query: 360  TPRDDGELG 368
               + G  G
Sbjct: 1030 PQGETGPAG 1038



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 64/241 (26%), Positives = 81/241 (33%), Gaps = 63/241 (26%)

Query: 105  IPPNDGMPGGPIPPGFF-----------QGPPGS--QPSPHAQPPPHNPSSMMGPHSQPF 151
            +P  +G+PG P  PGF            +GPPG   QP     P     + +MGP   P 
Sbjct: 823  VPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG 882

Query: 152  MSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQ--------------------- 190
             +    G P PP     QP  G PG +   P SM+  R+                     
Sbjct: 883  ENGP-VGPPGPP----GQP--GFPGLRGESP-SMETLRRLIQEELGKQLETRLAYLLAQM 934

Query: 191  --------QGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGMRPPPNSLGP--------- 232
                    QG P   G   +   P   GPMG PG    G G+  P   +GP         
Sbjct: 935  PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQG-GLEGPSGPIGPKGERGAKGD 993

Query: 233  -AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSS 291
               PG+ +    G P   P       Y+        GP G  GP G P +P P       
Sbjct: 994  PGAPGVGLRGEMGPPGI-PGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQC 1052

Query: 292  D 292
            D
Sbjct: 1053 D 1053


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 83/281 (29%), Positives = 93/281 (33%), Gaps = 63/281 (22%)

Query: 110  GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQ 169
            G PG P PPGF  G  GS P P           + GP   P       G P PP   G Q
Sbjct: 1159 GFPGPPGPPGF-PGKVGS-PGPPGPQAEKGSEGIRGPSGLP-------GSPGPPGPPGIQ 1209

Query: 170  PPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG----------PGPQNY 219
             P G+ G             + G P + G      PP  MGP G          PGP+  
Sbjct: 1210 GPAGLDGLDG----------KDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKG- 1258

Query: 220  GSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTP 279
              G   PP S G   PG    PGA  P   P                 GPPG  GPPG P
Sbjct: 1259 DCGKPGPPGSTG--RPGAEGEPGAMGPQGRP-----------------GPPGHVGPPGPP 1299

Query: 280  IMPSPA-----------DSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEP 328
              P PA            +T           P PPG      P  PG+DG  G  G    
Sbjct: 1300 GQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG--HPGPPGEPGTDGAAGKEGPPGK 1357

Query: 329  HHMNGSLG-SGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
                G  G  GD     +       G +  PG P   G +G
Sbjct: 1358 QGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMG 1398



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 86/321 (26%), Positives = 111/321 (34%), Gaps = 64/321 (19%)

Query: 102  LGNIPPNDGMPG-----GPIPPGFFQGPPGSQ--------PSPHA---QPPPHNPSSMMG 145
            L  +   DG PG     GP  P    GPPG +        P P     +P P   +   G
Sbjct: 1214 LDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPG 1273

Query: 146  PHSQP-FMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTR-QQGHPNMGGSMQRM 203
               +P  M P+  G P PP  +G   P G PG   +    +   R   G   + G   + 
Sbjct: 1274 AEGEPGAMGPQ--GRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQP 1331

Query: 204  NPPRGMGPMGPGPQNYGSGMRPPPNSLG-PAMPGINMGPGA-------------GRPWPN 249
             PP   GP G    +  +G   PP   G    PG    PGA             G P   
Sbjct: 1332 GPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGP 1391

Query: 250  PNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMP----SPADSTNSSD-------NIYTMI 298
              S +  P     P    G PG  GP G+P +P    S  D  N  +        I  M 
Sbjct: 1392 GKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMF 1451

Query: 299  NP-VPPGGSRSNFPM----------GPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNS 347
            +  +    SR  FPM           PG DG  G  G      + G +G     GLP   
Sbjct: 1452 DERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLP--- 1508

Query: 348  PNNISGISNPPGTPRDDGELG 368
                 G+   PGT  + G++G
Sbjct: 1509 -----GVRGLPGTKGEKGDIG 1524



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 79/275 (28%), Positives = 92/275 (33%), Gaps = 56/275 (20%)

Query: 110  GMPGGPIPPGF-----FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPI 164
            G PG P PPG       +GPPG + SP   P P  P    G    P + P   G      
Sbjct: 1018 GSPGLPGPPGLPGQRGEEGPPGMRGSP-GPPGPIGPPGFPGAVGSPGL-PGLQGERGLTG 1075

Query: 165  RMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG-PGPQNYGSGM 223
              G++   G PG QP  P +  P      P + G           G  G PGP     G+
Sbjct: 1076 LTGDKGEPGPPG-QPGYPGATGP------PGLPGIKGERGYTGSAGEKGEPGPPG-SEGL 1127

Query: 224  RPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPS 283
              PP   GP           G   P  NS             + G PG  GPPG P  P 
Sbjct: 1128 PGPPGPAGPR----------GERGPQGNSGEK------GDQGFQGQPGFPGPPGPPGFPG 1171

Query: 284  PADSTNSSDNIYTMINPVPPG-----GSR-----SNFPMGPGSDGPMGGMGGMEPHHMNG 333
               S            P PPG     GS      S  P  PG  GP G  G      ++G
Sbjct: 1172 KVGS------------PGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDG 1219

Query: 334  SLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
              G   + G P   P    G+  PPG     G  G
Sbjct: 1220 KDGKPGLRGDP--GPAGPPGLMGPPGFKGKTGHPG 1252



 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 77/284 (27%), Positives = 98/284 (34%), Gaps = 21/284 (7%)

Query: 95  AAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPS---PHAQPPPHNPSS--MMGPHSQ 149
           A  P P     PP  G+PG P  PG   GP G + S   P  + P   P    + G    
Sbjct: 446 AGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGD 505

Query: 150 PF-MSPRYAGGPRPPIRMGNQP-PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPR 207
           P  + P    G +  + +  +P P G PG         DP   +G P + G       P 
Sbjct: 506 PCEVCPTLPEGFQNFVGLPGKPGPKGEPG---------DPVPARGDPGIQGIKGEKGEPC 556

Query: 208 GMGPMGPGPQNYGS--GMRPPPNSLGPAMPGINMGPGA-GRPWPNPNSANSIPYSSSSPG 264
                  G Q+  S  G      S G  +PG+    G  G      N   + P  S  P 
Sbjct: 557 LSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPP 616

Query: 265 TYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMG 324
             VGP G  G  G P  P PA S     ++  +  P P G      P G G  G  G  G
Sbjct: 617 GPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAG 676

Query: 325 GMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
                   G  G+    G P  +     G+S  PG     G  G
Sbjct: 677 ERGLKGQKGDAGNPGDPGTPGTTGR--PGLSGEPGVQGPAGPKG 718



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 88/332 (26%), Positives = 104/332 (31%), Gaps = 90/332 (27%)

Query: 98  PSPVLGNIPPND----------GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPH 147
           P P L N+   D          G  G P PPGF  G PG Q     +          G  
Sbjct: 634 PCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF--GLPGKQ----GKAGERGLKGQKGDA 687

Query: 148 SQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQ-PLLPNSMDPTRQQGHPNMGGSMQRM-NP 205
             P       G P  P   G     G PG Q P  P           P++ G++  M   
Sbjct: 688 GNP-------GDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGR 740

Query: 206 PRGMGPMGP-GPQNYGSGMRPPPNSLGPAMPGINMGPGA----GRPWPNPNSANSIPYSS 260
           P   GP G  GP+  G   +P      P +PG+   PG     G P P            
Sbjct: 741 PGQPGPKGEQGPEGVGRPGKPGQ----PGLPGVQGPPGLKGVQGEPGP------------ 784

Query: 261 SSPGTYV----GPPGGGGPPGTPIMPSP--------ADSTNSSDNIYTMINPVPPGGSRS 308
             PG  V    G PG  G PG   +P P              S  +     PV P G+  
Sbjct: 785 --PGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASV 842

Query: 309 NFPMG-------------PGSDGPMGGMGGMEPHHMN----GSLGSGDIDGLP------- 344
           + P G             PG  GP G  G  EP   +    G L    + G P       
Sbjct: 843 SGPPGRDGQQGQTGLRGTPGEKGPRGEKG--EPGECSCPSQGDLIFSGMPGAPGLWMGSS 900

Query: 345 ----KNSPNNISGISNPPGTPRDDGELGGNFL 372
                  P  I G   PPG P   G  G N L
Sbjct: 901 WQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGL 932



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 65/261 (24%), Positives = 78/261 (29%), Gaps = 72/261 (27%)

Query: 102  LGNIPPNDGMPGGPIPPGF--------FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMS 153
            L  +P   G PG P PPG          +GPPG Q   +  P P       G   Q    
Sbjct: 1324 LAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGF-YGPPGPKGDPGAAGQKGQAGEK 1382

Query: 154  PRYAGGPRPPIRMGNQPPGGVPGT--QPLLPNSMDPTRQQGHPNMGGSM----------- 200
             R AG P  P + G+  P G PG   +   P +  P+   G P + GSM           
Sbjct: 1383 GR-AGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKR 1441

Query: 201  ------------------QRMNPPRGMG--PMGPGPQNYGSGMRPPPNSLGPAMPG---- 236
                               RM  P  M   P  PGP         P     P +PG    
Sbjct: 1442 FIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGR 1501

Query: 237  ---------------------INMGPGAGRPWPNPNSANSIP----YSSSSPGTYVGPPG 271
                                 I +G       P P      P      ++ P    G PG
Sbjct: 1502 EGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPG 1561

Query: 272  GGGPPGTPIMPSPADSTNSSD 292
              GPPG    P  A   N SD
Sbjct: 1562 IPGPPGPMGQPGKAGHCNPSD 1582



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 76/304 (25%), Positives = 102/304 (33%), Gaps = 49/304 (16%)

Query: 91  DYSAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNP---------- 140
           D +   APS   G      G  G P PPG  +G  G++ +   +  P  P          
Sbjct: 325 DSNVTLAPSGPKGG----KGERGLPGPPGS-KGEKGARGNDCVRISPDAPLQCAEGPKGE 379

Query: 141 ---SSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMG 197
              S  +GP   P       G      + G +  GG+ G    +P       + G   + 
Sbjct: 380 KGESGALGPSGLP-------GSTGEKGQKGEKGDGGIKG----VPGKPGRDGRPGEICVI 428

Query: 198 GSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIP 257
           G   +   P  +GP G   +    G+  PP    P  PG    PG G P P  +  +S  
Sbjct: 429 GPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPG---DPG-GPPGPKGDKGSSGI 484

Query: 258 YSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPM--GPG 315
                PG   G PG  G  G P    P       + +     P P G      P    PG
Sbjct: 485 PGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPG 544

Query: 316 SDGPMGGMGGMEP----------HHMNGSLG-SGDIDGLPKNSPNNISGISNPPGTPRDD 364
             G  G  G  EP           H+  S G SGD+ G P      + G +  PG   + 
Sbjct: 545 IQGIKGEKG--EPCLSCSSVVGAQHLVSSTGASGDV-GSPGFGLPGLPGRAGVPGLKGEK 601

Query: 365 GELG 368
           G  G
Sbjct: 602 GNFG 605



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 76/283 (26%), Positives = 92/283 (32%), Gaps = 69/283 (24%)

Query: 106  PPNDGMPGGPIPPGF--FQGPPGSQPSPHAQP-----------PPHNPSSMMGPHSQPFM 152
            PP  G+PG P PPG    QG PG+   P  QP             H   S+ G   Q   
Sbjct: 908  PP--GIPGPPGPPGVPGLQGVPGNNGLP-GQPGLTAELGSLPIEQHLLKSICGDCVQGQR 964

Query: 153  S-PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGP 211
            + P Y       +  G +   G+PG               G  N       +  PR    
Sbjct: 965  AHPGYL------VEKGEKGDQGIPGVP-------------GLDNCAQCFLSLERPRAEEA 1005

Query: 212  MGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPG 271
             G   +         P  +G   PG+   PG     P        P    SPG    PPG
Sbjct: 1006 RGDNSEG-------DPGCVGS--PGLPGPPGL----PGQRGEEGPPGMRGSPG----PPG 1048

Query: 272  GGGPPGTP-IMPSPADSTNSSDNIYTMI-----NPVPPGGSRSNFPMGPGSDGPMGGMGG 325
              GPPG P  + SP       +   T +      P PPG      P  PG+ GP G  G 
Sbjct: 1049 PIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQ-----PGYPGATGPPGLPGI 1103

Query: 326  MEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELG 368
                   GS G     G     P    G+  PPG     GE G
Sbjct: 1104 KGERGYTGSAGEKGEPG-----PPGSEGLPGPPGPAGPRGERG 1141



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 41/144 (28%), Positives = 49/144 (34%), Gaps = 29/144 (20%)

Query: 97   APSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRY 156
            A +P     P  DG PG P       G PGS P    Q        + G    P      
Sbjct: 1469 AAAPGRPGPPGKDGAPGRP-------GAPGS-PGLPGQIGREGRQGLPGVRGLPGTK--- 1517

Query: 157  AGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMG-----GSMQRMNPPRGMGP 211
              G +  I +G     G+PG          P   QG P  G     G M +   P   GP
Sbjct: 1518 --GEKGDIGIGIAGENGLPG----------PPGPQGPPGYGKMGATGPMGQQGIPGIPGP 1565

Query: 212  MGPGPQNYGSGMRPPPNSLGPAMP 235
             GP  Q   +G   P +  G AMP
Sbjct: 1566 PGPMGQPGKAGHCNPSDCFG-AMP 1588


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 82/311 (26%), Positives = 106/311 (34%), Gaps = 55/311 (17%)

Query: 105  IPPNDGMPGGPIPPGF--FQGPPGSQPSP--------------HAQPPPHNPSSMMGPHS 148
            IP   G+PG   PPGF   +GPPG Q                   Q  P  P+ ++GP  
Sbjct: 864  IPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQG 923

Query: 149  Q-----PFMSPRYAGGPRPPIRMGNQ-------------PPG-----------GVPGTQP 179
            +     P       G P PP   G               PPG           G PG + 
Sbjct: 924  KTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKG 983

Query: 180  LLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINM 239
              P    PT  +G     G +     P   GP+GP     G G+     S GP  P    
Sbjct: 984  -GPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAG---GIGLPGQSGSEGPVGPAGKK 1039

Query: 240  GPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMIN 299
            G    R  P P   + IP     P   +GPPG  GP G         +     +     +
Sbjct: 1040 GSRGERGPPGPTGKDGIP----GPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGD 1095

Query: 300  PVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDG-LPKNSPNNISGISNP 357
              PPG      P G PG  G  G  G   P  + G  G   + G +    P  + G+  P
Sbjct: 1096 AGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGP 1155

Query: 358  PGTPRDDGELG 368
            PG   + G++G
Sbjct: 1156 PGEKGEVGDVG 1166



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 86/295 (29%), Positives = 102/295 (34%), Gaps = 55/295 (18%)

Query: 106 PPND-GMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQP-----FMSPRYAGG 159
           PP   G+ G P P G   G PG +    A+ P   P  + GPH  P        P   G 
Sbjct: 480 PPGPVGLTGRPGPVGL-PGHPGLKGEEGAEGP-QGPRGLQGPHGPPGRVGKMGRPGADGA 537

Query: 160 PRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGH------PNMGGSMQRMNPPRGMGPMG 213
              P   G +   G  G  P LP         GH      P   G      PP   G  G
Sbjct: 538 RGLPGDTGPKGDRGFDGL-PGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596

Query: 214 -PGPQNYGSGMRPPPNSLG-PAMPGINMGPGA-------GRPWPNPNSANSIPYSSSSPG 264
            PGP+    G R  P   G P + GI+  PGA       G P P     N        P 
Sbjct: 597 EPGPRGL-LGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655

Query: 265 TYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-PGSDGPMGGM 323
             +G PG  GPPG                     NP  PG   S+ P+G PG +GP G  
Sbjct: 656 GLIGTPGEKGPPG---------------------NPGIPGLPGSDGPLGHPGHEGPTGEK 694

Query: 324 GGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQND 378
           G   P       GS    G P   P  + G S   G   + GE G +    F+ D
Sbjct: 695 GAQGPP------GSAGPPGYP--GPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGD 741



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 84/314 (26%), Positives = 103/314 (32%), Gaps = 82/314 (26%)

Query: 106  PPNDGMPGGPIPPGFF-----QGPPGSQPSPHAQPPPHNPSSM-----------MGPHSQ 149
            P   G PG P P G        GP G+   P  + PP    +            +GP   
Sbjct: 1213 PGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGD 1272

Query: 150  PFMS-----------PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGG 198
            P +S           P   GGP PP   G     G PG     P    P+   G     G
Sbjct: 1273 PGVSGIDGSPGEKGDPGDVGGPGPP---GASGEPGAPGP----PGKRGPSGHMGREGREG 1325

Query: 199  SMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGP----------AMPGINMGPGAGRPWP 248
                   P   GP GP  +    G R PP  +GP            PG+   PG   P P
Sbjct: 1326 EKGAKGEP---GPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGP-P 1381

Query: 249  NPNSANSIPYSSSSPGT-----------YVGPPGGGGPPGTPIMPSPADSTNSSDNIYTM 297
             P   + +P      G             +GPPG  G  G   +P               
Sbjct: 1382 GPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQG----------- 1430

Query: 298  INPVPPGGSRSNFPMG-PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKN-SPNNISGIS 355
                PPG      P G PG  GP+G +G   P  + G LG     G P +  P   +G +
Sbjct: 1431 ----PPG------PKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPA 1480

Query: 356  NPPGTPRDDGELGG 369
             PPG P    EL G
Sbjct: 1481 GPPGPPGAPAELHG 1494



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 88/330 (26%), Positives = 103/330 (31%), Gaps = 82/330 (24%)

Query: 110 GMPGGPIPPGF-----FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYA------- 157
           G  G P PPG       +GPPG    P  Q     P  ++GP   P  + R         
Sbjct: 569 GHVGQPGPPGEDGERGAEGPPG----PTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGA 624

Query: 158 ----------GGPRPPIRMGNQPPGGVPGTQ-----------------PLLPNSMDPTRQ 190
                     G P PP + GN    G+PG Q                 P LP S  P   
Sbjct: 625 PGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGH 684

Query: 191 QGHPNMGGSMQRMNPPRGMGPMG-PGPQNYG--SGMRPPPNSLGP----AMPGINMGPGA 243
            GH    G      PP   GP G PGP+     SG R      G       PG     G 
Sbjct: 685 PGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGL 744

Query: 244 -------GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGP---------PGTPIMPSPADS 287
                  G P P        P   +      GPPG  G          PG P  P P  S
Sbjct: 745 KGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGS 804

Query: 288 TNSSDNIYTMINPVPPGG--SRSNFPMGPGSDGPMGGMGGMEPHHMNGSLG----SGDI- 340
                       P+ P G   +S     PG +G  G  G        G+ G     GD+ 
Sbjct: 805 IG-------FPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVG 857

Query: 341 -DGLPK-NSPNNISGISNPPGTPRDDGELG 368
            DG P       + G+  PPG P   G  G
Sbjct: 858 QDGAPGIPGEKGLPGLQGPPGFPGPKGPPG 887



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 68/250 (27%), Positives = 87/250 (34%), Gaps = 67/250 (26%)

Query: 98   PSPVLGNIPPN-DGMPGGPIPPGFFQGPPG--------SQPSPHAQPPPHNPSSMMGPHS 148
            P  V G  PP   G PG P PPG  +GP G         +     +P P  P    GP  
Sbjct: 1288 PGDVGGPGPPGASGEPGAPGPPGK-RGPSGHMGREGREGEKGAKGEPGPDGPPGRTGP-- 1344

Query: 149  QPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRG 208
                     G   PP R+G +   G+PG               G P + G+  +M PP  
Sbjct: 1345 --------MGARGPPGRVGPEGLRGIPGPV-------------GEPGLLGAPGQMGPPGP 1383

Query: 209  MGPMG-------PGPQNYGS-----GMRPPPNSLGP----AMPGINMGPGA-GRPWPNPN 251
            +GP G        GP+         G+  PP   G      +PG+   PG  G P P P 
Sbjct: 1384 LGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGP-PG 1442

Query: 252  SANSIPY--------------SSSSPGTYV--GPPGGGGPPGTPIMPSPADSTNSSDNIY 295
               S+ +              S  SPG+    G  G  GPPG P  P+            
Sbjct: 1443 PIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFV 1502

Query: 296  TMINPVPPGG 305
             +  PV  GG
Sbjct: 1503 PVPLPVVEGG 1512



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 35/129 (27%), Positives = 40/129 (31%), Gaps = 48/129 (37%)

Query: 232 PAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSS 291
           P+     + PGAG        A   P        + GPPG  GP G      P       
Sbjct: 361 PSRTQFQIFPGAGE-----KGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGP------- 408

Query: 292 DNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNI 351
                   P PPG     FP  PG  GP G                  + G+P      I
Sbjct: 409 --------PGPPG-----FPGDPGPPGPAG------------------LPGIP-----GI 432

Query: 352 SGISNPPGT 360
            GI  PPGT
Sbjct: 433 DGIRGPPGT 441


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 83/288 (28%), Positives = 101/288 (35%), Gaps = 23/288 (7%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRP--P 163
            P   G PG P  PG  +G PG  P P   P    P    GP  +P    +  GG  P  P
Sbjct: 1310 PGRAGNPGTPGAPGL-KGSPGL-PGPRGDPGERGPR---GPKGEPGAPGQVIGGEGPGLP 1364

Query: 164  IRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRG-MGPMGPGPQNYGSG 222
             R G+  P G PG +  L +   P    G P  G +M+     RG  GP GPG      G
Sbjct: 1365 GRKGDPGPSGPPGPRGPLGDP-GPRGPPGLP--GTAMKGDKGDRGERGPPGPGEGGIAPG 1421

Query: 223  MRPPPNSLGPAMPGINMGPGA--GRPWPNPNSANSIPYSSSSPGTYV--GPPGGGGPPGT 278
                P   G   P   +GP    G    + + A  +P    SPG     GPPG  GP G 
Sbjct: 1422 EPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGD 1481

Query: 279  PIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSG 338
               P P               P  P GSR      PG  G  G  G   P    G  G  
Sbjct: 1482 RGFPGPLGEAGEKGER----GPPGPAGSRGL----PGVAGRPGAKGPEGPPGPTGRQGEK 1533

Query: 339  DIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSPSMTM 386
               G P +       ++ P G   D G  G       Q +   P + +
Sbjct: 1534 GEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL 1581



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 88/300 (29%), Positives = 107/300 (35%), Gaps = 41/300 (13%)

Query: 97   APSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRY 156
            AP  V+G   P  G+PG    PG   GPPG +  P   P P  P  + G   +     R 
Sbjct: 1351 APGQVIGGEGP--GLPGRKGDPG-PSGPPGPR-GPLGDPGPRGPPGLPGTAMKGDKGDRG 1406

Query: 157  AGGPRPPIRMGNQP-PGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPG 215
              GP  P   G  P   G+PG  P  P    P    G     G  +   P     P  PG
Sbjct: 1407 ERGPPGPGEGGIAPGEPGLPGL-PGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPG 1465

Query: 216  PQNYGSGMRPPPNSLGP----AMPGI--NMGPGAGRPWPNPNSANSIPYSSSSPGTYVGP 269
             Q    G R PP ++GP      PG     G    R  P P  +  +P  +  PG   GP
Sbjct: 1466 EQ----GPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGA-KGP 1520

Query: 270  PGGGGP------------PGTPIMPSPADSTNSSDNIYTMINPVPPGGSR----SNFPMG 313
             G  GP            PG P +  PA +    +     + P  P G+        P G
Sbjct: 1521 EGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK--GDVGPAGPRGATGVQGERGPPG 1578

Query: 314  ---PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP--KNSPNNISGISNPPGTPRDDGELG 368
               PG  GP G  G   P  + G  G     G P  K  P    G   P G    DGE+G
Sbjct: 1579 LVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR-PGPPGPVGPRGRDGEVG 1637



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 84/317 (26%), Positives = 105/317 (33%), Gaps = 61/317 (19%)

Query: 91   DYSAAAAPSPVLGNIPPND----GMPGGPIPPGFFQGPPGS----------------QPS 130
            D      P P  G I P +    G+PG P P G   GPPG                 QP 
Sbjct: 1404 DRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPV-GPPGKKGEKGDSEDGAPGLPGQPG 1462

Query: 131  PHAQPPPHNPSSMMGPHS-QPFMSPRYAGGPR----PPIRMGNQPPGGVPGTQPLL---- 181
               +  P  P   +GP   + F  P    G +    PP   G++   GV G         
Sbjct: 1463 SPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEG 1522

Query: 182  -PNSMDPTRQQGHPNMGGSMQRMNP----PRG----MGPMGPGPQNYGSGMRPPPNSLGP 232
             P       ++G P   G    + P    P+G    +GP GP       G R PP  + P
Sbjct: 1523 PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLP 1582

Query: 233  AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSD 292
              PG    PG   P         +   +  PG   GPPG  G PG P  P P        
Sbjct: 1583 GDPGPKGDPGDRGPI-------GLTGRAGPPGDS-GPPGEKGDPGRPGPPGPVGPRGRDG 1634

Query: 293  NIYTMINPVPPG-------GSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPK 345
             +    +  PPG                PG  GP+G  G        G  G    +G P 
Sbjct: 1635 EVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD------QGDPGEDGRNGSPG 1688

Query: 346  NS-PNNISGISNPPGTP 361
            +S P    G   PPG P
Sbjct: 1689 SSGPKGDRGEPGPPGPP 1705



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 86/321 (26%), Positives = 107/321 (33%), Gaps = 75/321 (23%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIR 165
            PP  G+PG P PPG    PPG  P      P    S   GP       P   G    P  
Sbjct: 2077 PP--GLPGTPGPPG----PPG--PKVSVDEPGPGLSGEQGP-------PGLKGAKGEPGS 2121

Query: 166  MGNQPPGG---VPGTQ--------------PLLPNSMDPTRQQGHPNMGGSMQRMNPPRG 208
             G+Q P G   VPG +              P LP        +G P + G      P  G
Sbjct: 2122 NGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGG 2181

Query: 209  MGPMGP----------GPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPY 258
             G  GP          GPQ   SG++  P   GP   G+  GP      P P   + +  
Sbjct: 2182 HGDPGPPGAPGLAGPAGPQG-PSGLKGEPGETGPPGRGLT-GPTGAVGLPGPPGPSGLVG 2239

Query: 259  SSSSPGT-----YVGPP---------------GGGGPPGTPIMPSPADSTNSSDNIYTMI 298
               SPG        G P               G  G PG+P +P P              
Sbjct: 2240 PQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKG--------- 2290

Query: 299  NPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLP-KNSPNNISGISNP 357
             P P G         PG+ G  G  GG+    + G  G+    GLP        +G +  
Sbjct: 2291 EPGPTGAPGQAVVGLPGAKGEKGAPGGL-AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE 2349

Query: 358  PGTPRDDGELGGNFLHSFQND 378
            PG P +DG+ G      F+ D
Sbjct: 2350 PGDPGEDGQKGAPGPKGFKGD 2370



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 79/293 (26%), Positives = 98/293 (33%), Gaps = 67/293 (22%)

Query: 106  PPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIR 165
            P  DG  G P P G F+G PG                 +G    P       G P PP  
Sbjct: 2353 PGEDGQKGAPGPKG-FKGDPG-----------------VGVPGSP-------GPPGPPGV 2387

Query: 166  MGNQPPGGVPGTQPLL--PNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGP-GPQNYGSG 222
             G+    G+PG   ++  P    P  + G P   G      PP   G  GP GP      
Sbjct: 2388 KGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPG---- 2443

Query: 223  MRPPPNSLGP----AMPGINMGPGAGRPWPNPNSAN-SIPYSSSSPGT-----YVGPPGG 272
               PP S+GP     + G    PG G P P        I      PG        GPPG 
Sbjct: 2444 ---PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGS 2500

Query: 273  GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMN 332
             G  G       A       +   ++ P  P G++ +     G  GP G  G   P   N
Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDM----GERGPRGLDGDKGPRGDN 2556

Query: 333  ------------GSLGSGDIDGL-----PKNSPNNISGISNPPGTPRDDGELG 368
                        G  GS  + GL     P+  P   +GI   PG+P  DG  G
Sbjct: 2557 GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQP-GAAGIPGDPGSPGKDGVPG 2608



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 86/312 (27%), Positives = 104/312 (33%), Gaps = 56/312 (17%)

Query: 98   PSPVLGNIPPND-GMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSP 154
            P PV G+  P   G PG  GP  P   QGP G +  P    PP     + GP        
Sbjct: 2176 PGPVGGHGDPGPPGAPGLAGPAGP---QGPSGLKGEPGETGPPGR--GLTGPTGA----- 2225

Query: 155  RYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSM----QRMNP----- 205
               G P PP   G   P G PG    LP  +  T + G P   G+      R +P     
Sbjct: 2226 --VGLPGPPGPSGLVGPQGSPG----LPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGS 2279

Query: 206  ---PRGMGPMG-PGPQNY-GSGMRPPPNSLG-PAMPGINMGPGAGRPWPNPNSANSIPYS 259
               P  +GP G PGP    G  +   P + G    PG   G   G P    +     P  
Sbjct: 2280 PGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG 2339

Query: 260  SSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG------ 313
                    G PG  G  G    P P         +    +P PPG       +G      
Sbjct: 2340 EKGEAGRAGEPGDPGEDGQKGAPGP-KGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPG 2398

Query: 314  -------PGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGE 366
                   PG  GP G MG   P    G  G    +G+P        G   PPG P   G 
Sbjct: 2399 APGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP--------GPLGPPGPPGSVGP 2450

Query: 367  LGGNFLHSFQND 378
             G + L   + D
Sbjct: 2451 PGASGLKGDKGD 2462



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 72/248 (29%), Positives = 87/248 (35%), Gaps = 51/248 (20%)

Query: 110  GMPGGPIPPGF--FQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMG 167
            G+PG P   G   F+GPPG    P   P    P+   G    P +  R +G    P   G
Sbjct: 1737 GLPGAPGERGIEGFRGPPG----PQGDPGVRGPAGEKGDRGPPGLDGR-SGLDGKPGAAG 1791

Query: 168  NQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGM-GPMGPGPQNYGSGMRPP 226
               P G  G       + DP R  G P + G        +G+ GP GP       G+   
Sbjct: 1792 PSGPNGAAG------KAGDPGRD-GLPGLRGE-------QGLPGPSGP------PGLPGK 1831

Query: 227  PNSLG-PAMPGINMGPGA----GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIM 281
            P   G P + G N  PG     GR     +S  S       P    G PG  GP G P +
Sbjct: 1832 PGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGL 1891

Query: 282  PSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDID 341
            P P                 PPG     FP  PG  GP G  G        G  G   + 
Sbjct: 1892 PGPVG---------------PPG---QGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLR 1933

Query: 342  GLPKNSPN 349
            G P + PN
Sbjct: 1934 GEPGSVPN 1941



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 77/276 (27%), Positives = 93/276 (33%), Gaps = 48/276 (17%)

Query: 110  GMPG--GPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMG 167
            G PG  GP+     QG PG +   +  P    P    G   +P       G P PP R+ 
Sbjct: 1661 GAPGVRGPVGEKGDQGDPG-EDGRNGSPGSSGPK---GDRGEP-------GPPGPPGRLV 1709

Query: 168  NQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPP 227
            +  PG     +P       P   +G P + G+          GP  PGPQ    G+R P 
Sbjct: 1710 DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGP--PGPQG-DPGVRGPA 1766

Query: 228  NSLGPAMP-------GINMGPGAGRPWPNPNSA---NSIPYSSSSPGT--YVGPPGGGGP 275
               G   P       G++  PGA  P   PN A      P     PG     G PG  GP
Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGP-SGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP 1825

Query: 276  PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSL 335
            PG P  P                +  P    ++  P  PG DG  G  G        G  
Sbjct: 1826 PGLPGKPGE--------------DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRD 1871

Query: 336  GSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNF 371
            G     G P      I G   PPG P   G  G  F
Sbjct: 1872 GPKGERGAP-----GILGPQGPPGLPGPVGPPGQGF 1902



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 51/182 (28%), Positives = 61/182 (33%), Gaps = 30/182 (16%)

Query: 187  PTRQQGHPNMGGSMQRMNPPRGMGPMG----PGPQNYGSGMRPPPNSLGPAMPGINMGPG 242
            P  Q+G P   G   ++ PP   G  G    PGPQ       PP ++      G    PG
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQG------PPGSATAKGERGF---PG 1302

Query: 243  A-GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPV 301
            A GRP          P  + +PGT    PG  G  G+P +P P               P 
Sbjct: 1303 ADGRP--------GSPGRAGNPGT----PGAPGLKGSPGLPGPRGDPGERGPRGPKGEPG 1350

Query: 302  PPG----GSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNP 357
             PG    G     P   G  GP G  G   P    G  G   + G          G   P
Sbjct: 1351 APGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGP 1410

Query: 358  PG 359
            PG
Sbjct: 1411 PG 1412



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 65/233 (27%), Positives = 80/233 (34%), Gaps = 53/233 (22%)

Query: 157  AGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGP 216
            +G   PP   G + P G PG + L  +  DP   QG P +    +        GP GP  
Sbjct: 1984 SGEQGPP---GKEGPIGFPGERGLKGDRGDPG-PQGPPGLALGER--------GPPGP-- 2029

Query: 217  QNYGSGMRPPPNSLG-PAMPGINMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGG 274
                SG+   P   G P +PG   G G AGRP                     GPPG  G
Sbjct: 2030 ----SGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRD---GPPGLPG 2082

Query: 275  PPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMG-------PGSDGPMGGMGGME 327
             PG P  P P  S          ++   PG S    P G       PGS+G  G  G   
Sbjct: 2083 TPGPPGPPGPKVS----------VDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRG 2132

Query: 328  PHHMNGSLGSGDIDGLPKN----------SPNNISGISNPPGTPRDDGELGGN 370
               + G  G     G   N           P    G+  P G P   G +GG+
Sbjct: 2133 VPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPP---GPVGGH 2182



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 76/291 (26%), Positives = 92/291 (31%), Gaps = 35/291 (12%)

Query: 109  DGMPGGPIPPGFF--QGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPR--PPI 164
            DG  G    PG    QGPPG  P P   P    P    G   +       + G +  P  
Sbjct: 1871 DGPKGERGAPGILGPQGPPGL-PGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGE 1929

Query: 165  RMGNQPPGGVPGTQPLLPNS---MDPTRQ--QGHPNMGGSMQRMNPPRGMGPMGPGPQNY 219
            R     PG VP    LL  +       R+  +      GS   + P R  GP G      
Sbjct: 1930 RGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPV-PERRRGPKGD----- 1983

Query: 220  GSGMRPPPNSLGP-AMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGT 278
             SG + PP   GP   PG   G    R  P P     +      P    G  G  G PG 
Sbjct: 1984 -SGEQGPPGKEGPIGFPG-ERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGI 2041

Query: 279  PIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGP----GSDGPMGGMGGMEPHHMNGS 334
            P +P  A     +           PG        G     G DGP G  G   P    G 
Sbjct: 2042 PGLPGRAGGVGEAGR---------PGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGP 2092

Query: 335  LGSGDIDG---LPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSP 382
              S D  G     +  P  + G    PG+  D G  G   +   + D   P
Sbjct: 2093 KVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEP 2143



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 78/293 (26%), Positives = 103/293 (35%), Gaps = 46/293 (15%)

Query: 109  DGMPGGPIPPGFFQGPPGSQP---------SPHAQPPPHNPSSMMGPHSQPFMSPRYAGG 159
            DG PG   P G   GPPGS+          S   +    + + ++GP       PR A G
Sbjct: 2483 DGRPGQEGPRGL-TGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG-----PRGAKG 2536

Query: 160  PRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQ--QGHPNMGGSMQRMNPPRGMGPMGPGPQ 217
                  MG + P G+ G +    ++ DP  +  +G P   GS      P   G +GP  Q
Sbjct: 2537 D-----MGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSA---GLPGLRGLLGPQGQ 2588

Query: 218  NYGSGMRPPPNSLGP-AMPGINMGPG-AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGP 275
               +G+   P S G   +PGI    G  G   P           +       G  G  GP
Sbjct: 2589 PGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGP 2648

Query: 276  PGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMG------GMEPH 329
            PG P +               M  P  PG  +S  P   G  GP G  G           
Sbjct: 2649 PGRPGLAGHKGE---------MGEPGVPG--QSGAPGKEGLIGPKGDRGFDGQPGPKGDQ 2697

Query: 330  HMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSP 382
               G  G+  I G P  S N+  G + PPG P   G  G   L   + +   P
Sbjct: 2698 GEKGERGTPGIGGFPGPSGND--GSAGPPGPPGSVGPRGPEGLQGQKGERGPP 2748



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 48/187 (25%), Positives = 57/187 (30%), Gaps = 40/187 (21%)

Query: 100  PVLGNIPPNDGMPGGPIPPGF--------FQGP---------------PGSQPSPHAQPP 136
            P    IP + G PG    PG         F GP                G +       P
Sbjct: 2589 PGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGP 2648

Query: 137  PHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGT--QPLLPNSMDPTRQQGHP 194
            P  P   +  H      P   G    P + G   P G  G   QP          ++G P
Sbjct: 2649 PGRPG--LAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTP 2706

Query: 195  NMGG---------SMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPG--- 242
             +GG         S     PP  +GP GP       G R PP       PG+   PG   
Sbjct: 2707 GIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERG 2766

Query: 243  -AGRPWP 248
              GRP P
Sbjct: 2767 EQGRPGP 2773



 Score = 37.4 bits (85), Expect = 0.023
 Identities = 55/232 (23%), Positives = 75/232 (32%), Gaps = 28/232 (12%)

Query: 123  GPPGSQPSPHAQPPPHNPS--SMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPL 180
            G  GS+  P  +     P    ++GP  QP      AG P  P   G+    GVPG +  
Sbjct: 2560 GDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGA----AGIPGDP---GSPGKDGVPGIRGE 2612

Query: 181  LPNS--MDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLG-PAMPGI 237
              +   M P   +G   + G+          G  GP  +    G+      +G P +PG 
Sbjct: 2613 KGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGR---PGLAGHKGEMGEPGVPGQ 2669

Query: 238  NMGPGA-------------GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSP 284
            +  PG              G+P P  +        +   G + GP G  G  G P  P  
Sbjct: 2670 SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGS 2729

Query: 285  ADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLG 336
                             PPG      P  PG+ G  G  G   P    G  G
Sbjct: 2730 VGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.136    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,221,076
Number of Sequences: 37866
Number of extensions: 2172421
Number of successful extensions: 22600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 288
Number of HSP's successfully gapped in prelim test: 1518
Number of HSP's that attempted gapping in prelim test: 8559
Number of HSP's gapped (non-prelim): 6313
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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