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Search of human proteins with 218156270
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
(334 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 676 0.0
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 676 0.0
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 628 e-180
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 628 e-180
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 553 e-157
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 547 e-156
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 532 e-151
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 516 e-146
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 447 e-126
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 447 e-126
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 184 1e-46
gi|52630447 palmitoylated membrane protein 2 [Homo sapiens] 166 3e-41
gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] 165 5e-41
gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] 165 6e-41
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 158 7e-39
gi|4505237 palmitoylated membrane protein 1 [Homo sapiens] 141 9e-34
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 140 2e-33
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 140 2e-33
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 137 1e-32
gi|95089461 discs large homolog 5 [Homo sapiens] 129 4e-30
gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens] 122 6e-28
gi|10092691 tight junction protein 3 [Homo sapiens] 100 1e-21
gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 98 9e-21
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 98 9e-21
gi|226874833 guanylate kinase 1 isoform b [Homo sapiens] 95 8e-20
gi|226874831 guanylate kinase 1 isoform a [Homo sapiens] 95 8e-20
gi|4504221 guanylate kinase 1 isoform b [Homo sapiens] 95 8e-20
gi|42518065 tight junction protein 2 (zona occludens 2) isoform ... 91 1e-18
gi|42518070 tight junction protein 2 (zona occludens 2) isoform ... 91 1e-18
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 62 5e-10
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 676 bits (1743), Expect = 0.0
Identities = 334/334 (100%), Positives = 334/334 (100%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW
Sbjct: 416 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 475
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT 120
WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT
Sbjct: 476 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT 535
Query: 121 KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK 180
KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK
Sbjct: 536 KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK 595
Query: 181 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 240
RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV
Sbjct: 596 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 655
Query: 241 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA 300
SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA
Sbjct: 656 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA 715
Query: 301 IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
Sbjct: 716 IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 749
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 676 bits (1743), Expect = 0.0
Identities = 334/334 (100%), Positives = 334/334 (100%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW
Sbjct: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT 120
WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT
Sbjct: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT 120
Query: 121 KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK 180
KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK
Sbjct: 121 KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK 180
Query: 181 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 240
RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV
Sbjct: 181 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 240
Query: 241 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA 300
SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA
Sbjct: 241 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA 300
Query: 301 IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
Sbjct: 301 IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 628 bits (1619), Expect = e-180
Identities = 319/352 (90%), Positives = 321/352 (91%), Gaps = 18/352 (5%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW
Sbjct: 624 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 683
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGY-- 118
WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKG +
Sbjct: 684 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIF 743
Query: 119 ----------------GTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLI 162
+ RGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLI
Sbjct: 744 SRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLI 803
Query: 163 SEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTS 222
SEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTS
Sbjct: 804 SEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTS 863
Query: 223 VQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKK 282
VQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKK
Sbjct: 864 VQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKK 923
Query: 283 TYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
TYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
Sbjct: 924 TYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 975
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 628 bits (1619), Expect = e-180
Identities = 319/352 (90%), Positives = 321/352 (91%), Gaps = 18/352 (5%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW
Sbjct: 519 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 578
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGY-- 118
WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKG +
Sbjct: 579 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIF 638
Query: 119 ----------------GTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLI 162
+ RGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLI
Sbjct: 639 SRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLI 698
Query: 163 SEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTS 222
SEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTS
Sbjct: 699 SEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTS 758
Query: 223 VQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKK 282
VQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKK
Sbjct: 759 VQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKK 818
Query: 283 TYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
TYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
Sbjct: 819 TYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 870
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 553 bits (1424), Expect = e-157
Identities = 267/334 (79%), Positives = 304/334 (91%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMN SMSSGSGSLRT++KRSLYVRA+FDYD+++DS LPSQGLSF YGDILHVINASDDEW
Sbjct: 484 MMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEW 543
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT 120
WQAR V G+SE++GVIPSK+RVE+KERARLKTVKF+A+ G+I+S D PGL DD YG
Sbjct: 544 WQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGA 603
Query: 121 KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK 180
K L+GQED ILSYEPVTRQEI+Y RPVIILGPMKDR+NDDLISEFP KFGSCVPHTTRP+
Sbjct: 604 KNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPR 663
Query: 181 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 240
RD EVDG+DYHFV+SREQMEKDIQ++KFIEAGQ+NDNLYGTS+QSVR VAERGKHCILDV
Sbjct: 664 RDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDV 723
Query: 241 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA 300
SGNAIKRLQ AQLYPIAIFIKP+S+E LMEMN+R T EQA K YD+A+KLEQEFGEYFTA
Sbjct: 724 SGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTA 783
Query: 301 IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
IVQGD+LE+IYN+ K +IE+QSG +IW+PS EKL
Sbjct: 784 IVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 817
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 547 bits (1409), Expect = e-156
Identities = 271/344 (78%), Positives = 308/344 (89%), Gaps = 13/344 (3%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMN S+SSGSGSLRT+QKRSLYVRA+FDYDK+KDSGLPSQGL+FK+GDILHVINASDDEW
Sbjct: 564 MMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEW 623
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPG-LGDDGY- 118
WQAR+V +G+S+E+GVIPSKRRVE+KERARLKTVKFN+K KG+IP +G G
Sbjct: 624 WQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTR---DKGEIPDDMGSKGLK 680
Query: 119 --------GTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFG 170
+ RGQE+ +LSYEPV +QE+NYTRPVIILGPMKDRINDDLISEFPDKFG
Sbjct: 681 HVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFPDKFG 740
Query: 171 SCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVA 230
SCVPHTTRPKRDYEVDGRDYHFV SREQMEKDIQEHKFIEAGQYN++LYGTSVQSVR VA
Sbjct: 741 SCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVA 800
Query: 231 ERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKL 290
E+GKHCILDVSGNAIKRLQ+AQLYPI+IFIKP+S+E +MEMNKRLTEEQA+KT++RA+KL
Sbjct: 801 EKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKL 860
Query: 291 EQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
EQEF E+FTAIVQGDTLEDIYNQ K +IEEQSG +IW+P+KEKL
Sbjct: 861 EQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPAKEKL 904
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 532 bits (1371), Expect = e-151
Identities = 267/365 (73%), Positives = 304/365 (83%), Gaps = 33/365 (9%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMN S+SSGSGSLRT+QKRSLYVRA+FDYDK+KDSGLPSQGL+FK+GDILHVINASDDEW
Sbjct: 564 MMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEW 623
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPG------------------ 102
WQAR+V +G+S+E+GVIPSKRRVE+KERARLKTVKFN+K
Sbjct: 624 WQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRDKGQSFNDKRKKNLFSRK 683
Query: 103 -------------VIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVII 149
D+ + D + RGQE+ +LSYEPV +QE+NYTRPVII
Sbjct: 684 FPFYKNKDQSEQETSDADQHVTSNASDS--ESSYRGQEEYVLSYEPVNQQEVNYTRPVII 741
Query: 150 LGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFI 209
LGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFV SREQMEKDIQEHKFI
Sbjct: 742 LGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFI 801
Query: 210 EAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLM 269
EAGQYN++LYGTSVQSVR VAE+GKHCILDVSGNAIKRLQ+AQLYPI+IFIKP+S+E +M
Sbjct: 802 EAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIM 861
Query: 270 EMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIP 329
EMNKRLTEEQA+KT++RA+KLEQEF E+FTAIVQGDTLEDIYNQ K +IEEQSG +IW+P
Sbjct: 862 EMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVP 921
Query: 330 SKEKL 334
+KEKL
Sbjct: 922 AKEKL 926
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 516 bits (1328), Expect = e-146
Identities = 260/366 (71%), Positives = 300/366 (81%), Gaps = 32/366 (8%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
MMN SMSSGSGSLRT++KRSLYVRA+FDYD+++DS LPSQGLSF YGDILHVINASDDEW
Sbjct: 147 MMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEW 206
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIP--------- 111
WQAR V G+SE++GVIPSK+RVE+KERARLKTVKF+A+ G+I+S I
Sbjct: 207 WQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRL 266
Query: 112 -----------------GLGDDGYGTKTL------RGQEDLILSYEPVTRQEINYTRPVI 148
+ + G + T +GQED ILSYEPVTRQEI+Y RPVI
Sbjct: 267 SRKFPFYKSKENMAQESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVI 326
Query: 149 ILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKF 208
ILGPMKDR+NDDLISEFP KFGSCVPHTTRP+RD EVDG+DYHFV+SREQMEKDIQ++KF
Sbjct: 327 ILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKF 386
Query: 209 IEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPL 268
IEAGQ+NDNLYGTS+QSVR VAERGKHCILDVSGNAIKRLQ AQLYPIAIFIKP+S+E L
Sbjct: 387 IEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEAL 446
Query: 269 MEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWI 328
MEMN+R T EQA K YD+A+KLEQEFGEYFTAIVQGD+LE+IYN+ K +IE+QSG +IW+
Sbjct: 447 MEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWV 506
Query: 329 PSKEKL 334
PS EKL
Sbjct: 507 PSPEKL 512
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 447 bits (1150), Expect = e-126
Identities = 213/334 (63%), Positives = 270/334 (80%), Gaps = 20/334 (5%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
+MN S+ SG+ SLR+N KR Y+RA+FDYDK+KD G SQ LSF++GD+LHVI+ASD+EW
Sbjct: 454 LMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEW 513
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT 120
WQARRV + +++++G IPSKRRVER+E +RLK + + G
Sbjct: 514 WQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGS----------------- 556
Query: 121 KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK 180
+G+ED +LSYE VT+ E++Y RP+IILGP KDR NDDL+SEFPDKFGSCVPHTTRPK
Sbjct: 557 ---QGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPK 613
Query: 181 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 240
R+YE+DGRDYHFV SRE+MEKDIQ HKFIEAGQYN +LYGTSVQSVR VAE+GKHCILDV
Sbjct: 614 REYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDV 673
Query: 241 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA 300
S NA++RLQ A L+PIAIFI+PRSLE ++E+NKR+TEEQA+K +DRA KLEQEF E F+A
Sbjct: 674 SANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSA 733
Query: 301 IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
IV+GD+ E+IY++ K VIE+ SGP+IW+P++E+L
Sbjct: 734 IVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 767
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 447 bits (1150), Expect = e-126
Identities = 213/334 (63%), Positives = 270/334 (80%), Gaps = 20/334 (5%)
Query: 1 MMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW 60
+MN S+ SG+ SLR+N KR Y+RA+FDYDK+KD G SQ LSF++GD+LHVI+ASD+EW
Sbjct: 408 LMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEW 467
Query: 61 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT 120
WQARRV + +++++G IPSKRRVER+E +RLK + + G
Sbjct: 468 WQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGS----------------- 510
Query: 121 KTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPK 180
+G+ED +LSYE VT+ E++Y RP+IILGP KDR NDDL+SEFPDKFGSCVPHTTRPK
Sbjct: 511 ---QGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPK 567
Query: 181 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 240
R+YE+DGRDYHFV SRE+MEKDIQ HKFIEAGQYN +LYGTSVQSVR VAE+GKHCILDV
Sbjct: 568 REYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDV 627
Query: 241 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTA 300
S NA++RLQ A L+PIAIFI+PRSLE ++E+NKR+TEEQA+K +DRA KLEQEF E F+A
Sbjct: 628 SANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSA 687
Query: 301 IVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 334
IV+GD+ E+IY++ K VIE+ SGP+IW+P++E+L
Sbjct: 688 IVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 721
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 184 bits (467), Expect = 1e-46
Identities = 120/335 (35%), Positives = 182/335 (54%), Gaps = 36/335 (10%)
Query: 21 LYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVI 78
++V+A FDYD S D +P + GLSF+ GDILHVI+ D WWQA R E + G++
Sbjct: 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLV 407
Query: 79 PSKRRVERKERARLKTVKFNAKPGVIDSKGDI---------------PGLGDDGYGTKTL 123
P K +++E A +T++ + +P + G + +D Y + +
Sbjct: 408 PGKSFQQQRE-AMKQTIEEDKEP---EKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
Query: 124 RGQEDLILSYEPVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPK 180
E++ L ++P R+ RP+I++GP ++ + L+++ D+F S VPHTTR +
Sbjct: 464 LTYEEMSLYHQPANRK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR 518
Query: 181 RDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDV 240
RD EV GRDYHFV SR+ E DI KFIE G++ NLYGTS+ SVR V GK C+L +
Sbjct: 519 RDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSL 577
Query: 241 SGNAIKRLQVAQLYPIAIFIKPRSLEPLMEM----NKRLTEEQAKKTYDRAIKLEQEFGE 296
++K L+ + L P IFI P S E L + K E+ ++ ++ ++EQ G
Sbjct: 578 RTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGH 637
Query: 297 YF-TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 330
YF TAIV D L+ Y + +I + W+PS
Sbjct: 638 YFDTAIVNSD-LDKAYQELLRLINKLDTEPQWVPS 671
>gi|52630447 palmitoylated membrane protein 2 [Homo sapiens]
Length = 552
Score = 166 bits (420), Expect = 3e-41
Identities = 102/329 (31%), Positives = 172/329 (52%), Gaps = 25/329 (7%)
Query: 19 RSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMG 76
R ++V+ FDYD ++DS +P + GL F GD+L ++N D WWQA V EG S G
Sbjct: 226 RQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHV--EGGSA--G 281
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGY---GTKTLRGQEDLILSY 133
+IPS+ E+++ + ++ G + G + G TK +L Y
Sbjct: 282 LIPSQLLEEKRKAFVKRDLELTPNSGTLC--GSLSGKKKKRMMYLTTKNAEFDRHELLIY 339
Query: 134 EPVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDY 190
E V R + ++++G + + + LI PD++G+ VP+T+R +D E +G+ Y
Sbjct: 340 EEVARMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGY 399
Query: 191 HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQV 250
FV SR +ME D++ +++E G+Y NLYGT + S+R V GK C+LDV+ A+K L+
Sbjct: 400 SFV-SRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRT 458
Query: 251 AQLYPIAIFIKPRSLEPLMEMN----------KRLTEEQAKKTYDRAIKLEQEFGEYFTA 300
A+ P +FI+ E L MN K+LTE ++T + + ++++ +G YF
Sbjct: 459 AEFVPYVVFIEAPDFETLRAMNRAALESGISTKQLTEADLRRTVEESSRIQRGYGHYFDL 518
Query: 301 IVQGDTLEDIYNQCKLVIEEQSGPFIWIP 329
+ LE + + + +E+ W+P
Sbjct: 519 CLVNSNLERTFRELQTAMEKLRTEPQWVP 547
>gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
Length = 585
Score = 165 bits (418), Expect = 5e-41
Identities = 108/360 (30%), Positives = 186/360 (51%), Gaps = 51/360 (14%)
Query: 17 QKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSE- 73
++ +++RA+F Y+ +D +P Q GL F+ +L V++ D WWQA+RV GD+
Sbjct: 225 KESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---GDTNL 281
Query: 74 EMGVIPSKRRVERKERAR-----LKTVKFNAKPG--------VIDSKGDIPG-------- 112
G+IPSK ER+ R L + + KP D +G + G
Sbjct: 282 RAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRR 341
Query: 113 ---------LGDDGYGTKTLRGQEDLILSYEPVTR---QEINYTRPVIILGPMKDRIND- 159
LG G + + +L+YE V R Q R V+++G + R+++
Sbjct: 342 SFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHEL 401
Query: 160 --DLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDN 217
+++E P FG VPHTTRP++ +E +G +YHFV S++ E D+ +KF+E G+Y +N
Sbjct: 402 KQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQAFEADLHHNKFLEHGEYKEN 460
Query: 218 LYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPR--------SLEPLM 269
LYGTS+++++ V + K C++DV A+K+L+ ++ P IF+KP + P
Sbjct: 461 LYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPAC 520
Query: 270 EMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIP 329
E +EQ ++ A +++ +G A++ + L+ Y+Q K+V+E+ S W+P
Sbjct: 521 EDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVP 580
>gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]
Length = 576
Score = 165 bits (417), Expect = 6e-41
Identities = 112/364 (30%), Positives = 175/364 (48%), Gaps = 55/364 (15%)
Query: 9 GSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRV 66
GS +++ ++++A+FDY+ ++D +P + GLSFK GDIL +++ D WWQA+
Sbjct: 219 GSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKH- 277
Query: 67 MLEGDSE-EMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRG 125
E D+ G+IPSK ER+ R +P ++ + G+
Sbjct: 278 --EADANPRAGLIPSKHFQERRLALR--------RPEILVQPLKVSNRKSSGFRKSFRLS 327
Query: 126 QEDL-------------------ILSYEPVT---RQEINYTRPVIILGPMKDRIND---D 160
++D + +YE VT RQ R V+++GP+ +N+
Sbjct: 328 RKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRK 387
Query: 161 LISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYG 220
L+ +G VPHTTR +R E DG +Y F IS+ E D+Q +KFIE G+Y +N YG
Sbjct: 388 LLISDTQHYGVTVPHTTRARRSQESDGVEYIF-ISKHLFETDVQNNKFIEYGEYKNNYYG 446
Query: 221 TSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKR------ 274
TS+ SVR V + K C+LDV + +K L+ + P IFIKP S+E L E K
Sbjct: 447 TSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISS 506
Query: 275 ---------LTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPF 325
TEE ++ A +E ++G F I+ D L +N+ K ++
Sbjct: 507 RDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETET 566
Query: 326 IWIP 329
W+P
Sbjct: 567 HWVP 570
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 158 bits (399), Expect = 7e-39
Identities = 103/328 (31%), Positives = 168/328 (51%), Gaps = 25/328 (7%)
Query: 19 RSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMG 76
+ ++V+ FDY+ D+ +P + GL F G+IL ++N D WWQA V G + G
Sbjct: 216 QQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSA---G 272
Query: 77 VIPSKRRVERKERARLKTVKFNAKP--GVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYE 134
+IPS+ +E K +A ++ N+ P G I SK + T+ I YE
Sbjct: 273 LIPSQF-LEEKRKAFVRRDWDNSGPFCGTISSKKKKKMMY---LTTRNAEFDRHEIQIYE 328
Query: 135 PVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYH 191
V + + ++++G + + + I P +FG+ VP T+R R+ E DG+ Y
Sbjct: 329 EVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYK 388
Query: 192 FVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVA 251
FV SR +ME DI+ K++E G+Y NLYGT + S+ V + G+ CILDV+ A+K L+ +
Sbjct: 389 FV-SRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTS 447
Query: 252 QLYPIAIFIKPRSLEPLMEMNKR----------LTEEQAKKTYDRAIKLEQEFGEYFTAI 301
+ P +FI LE L M+K LT+ KKT D + ++++ + YF I
Sbjct: 448 EFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLI 507
Query: 302 VQGDTLEDIYNQCKLVIEEQSGPFIWIP 329
+ D L+ + + + IE+ W+P
Sbjct: 508 IINDNLDKAFEKLQTAIEKLRMEPQWVP 535
>gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]
Length = 466
Score = 141 bits (355), Expect = 9e-34
Identities = 92/320 (28%), Positives = 159/320 (49%), Gaps = 30/320 (9%)
Query: 21 LYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEM-GV 77
+++RA FDYD KD+ +P + GL F GDI+ +IN D WWQ R +EG S+E G+
Sbjct: 161 MFMRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINKDDSNWWQGR---VEGSSKESAGL 217
Query: 78 IPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDL-----ILS 132
IPS E + V A+ ++ P Y K L + ++S
Sbjct: 218 IPSPELQEWR-------VASMAQSAPSEAPSCSPFGKKKKYKDKYLAKHSSIFDQLDVVS 270
Query: 133 YEPVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRD 189
YE V R + ++++G + I + L+S+ P+KF VP+TTRP R E DG++
Sbjct: 271 YEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKE 330
Query: 190 YHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQ 249
YHF IS E+M ++I ++F+E G Y N++GT ++V + ++ K ILD+ +K ++
Sbjct: 331 YHF-ISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVR 389
Query: 250 VAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLED 309
A+L P +FI P E ++L ++ + ++ YF + + +++
Sbjct: 390 TAELSPFIVFIAPTDQGTQTEALQQLQKDSE--------AIRSQYAHYFDLSLVNNGVDE 441
Query: 310 IYNQCKLVIEEQSGPFIWIP 329
+ + ++ W+P
Sbjct: 442 TLKKLQEAFDQACSSPQWVP 461
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 140 bits (352), Expect = 2e-33
Identities = 87/316 (27%), Positives = 158/316 (50%), Gaps = 17/316 (5%)
Query: 19 RSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMG 76
R +YVRA F+YD +KD +P + G+ F+ GDI+ +I+ D WWQ + + + G
Sbjct: 590 RQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGK--LENSKNGTAG 647
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPV 136
+IPS E R+ + + G Y K L +++YE V
Sbjct: 648 LIPSPELQEW----RVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEV 703
Query: 137 TRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFV 193
+ + +++LG + I + LI++ PD+F +PHTTRP + E +G++Y+FV
Sbjct: 704 VKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFV 763
Query: 194 ISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQL 253
S +QM +DI ++++E G + D +YGT ++++R + E+G ILDV A+K L+ A+
Sbjct: 764 -SHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEF 822
Query: 254 YPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQ 313
P +FI ++ P + ++ L Q + L++ + YF + + +++
Sbjct: 823 APFVVFIAAPTITPGLNEDESLQRLQKESDI-----LQRTYAHYFDLTIINNEIDETIRH 877
Query: 314 CKLVIEEQSGPFIWIP 329
+ +E W+P
Sbjct: 878 LEEAVELVCTAPQWVP 893
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 140 bits (352), Expect = 2e-33
Identities = 87/316 (27%), Positives = 158/316 (50%), Gaps = 17/316 (5%)
Query: 19 RSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMG 76
R +YVRA F+YD +KD +P + G+ F+ GDI+ +I+ D WWQ + + + G
Sbjct: 613 RQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGK--LENSKNGTAG 670
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPV 136
+IPS E R+ + + G Y K L +++YE V
Sbjct: 671 LIPSPELQEW----RVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEV 726
Query: 137 TRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFV 193
+ + +++LG + I + LI++ PD+F +PHTTRP + E +G++Y+FV
Sbjct: 727 VKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFV 786
Query: 194 ISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQL 253
S +QM +DI ++++E G + D +YGT ++++R + E+G ILDV A+K L+ A+
Sbjct: 787 -SHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEF 845
Query: 254 YPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQ 313
P +FI ++ P + ++ L Q + L++ + YF + + +++
Sbjct: 846 APFVVFIAAPTITPGLNEDESLQRLQKESDI-----LQRTYAHYFDLTIINNEIDETIRH 900
Query: 314 CKLVIEEQSGPFIWIP 329
+ +E W+P
Sbjct: 901 LEEAVELVCTAPQWVP 916
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 137 bits (346), Expect = 1e-32
Identities = 89/318 (27%), Positives = 159/318 (50%), Gaps = 16/318 (5%)
Query: 19 RSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMG 76
R +YVRA F+YD +KD +P + G+ F+ GDI+ +I+ D WWQ + + + G
Sbjct: 584 RQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGK--LENSKNGTAG 641
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTK--TLRGQEDLILSYE 134
+IPS E + + G D Y K + Q DL+ +YE
Sbjct: 642 LIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLV-TYE 700
Query: 135 PVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYH 191
V + + +++LG + I + LI++ PD+F +PHTTRP + E +G++Y+
Sbjct: 701 EVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYY 760
Query: 192 FVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVA 251
FV S +QM +DI ++++E G + D +YGT ++++R + E+G ILDV A+K L+ A
Sbjct: 761 FV-SHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTA 819
Query: 252 QLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIY 311
+ P +FI ++ P + ++ L Q + L++ + YF + + +++
Sbjct: 820 EFAPFVVFIAAPTITPGLNEDESLQRLQKESDI-----LQRTYAHYFDLTIINNEIDETI 874
Query: 312 NQCKLVIEEQSGPFIWIP 329
+ +E W+P
Sbjct: 875 RHLEEAVELVCTAPQWVP 892
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 129 bits (324), Expect = 4e-30
Identities = 94/342 (27%), Positives = 168/342 (49%), Gaps = 51/342 (14%)
Query: 20 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW---WQARRVMLEGDSEEMG 76
S Y+RA+ YD+ D Q LSFK DIL+V + W A ++ + G
Sbjct: 1595 SFYIRAL--YDRLADV---EQELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRG 1649
Query: 77 VIPSKRRVERKERARL------------KTVKFNAKPGVIDSK------GDIPG---LGD 115
IPSK ++++ RL KT+ A+ K G G L
Sbjct: 1650 QIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLAL 1709
Query: 116 DGYGTKTLRGQEDLI-LSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVP 174
D + + ++ ED + L+Y+ V + + RPV+ILGP+ D + + L++E P KF C
Sbjct: 1710 DAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPL 1769
Query: 175 HTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGK 234
+ S++ +E+ +++ F++ + + + T+V S++ + E+ +
Sbjct: 1770 EVMKA---------------SQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR 1814
Query: 235 HCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLME------MNKRLTEEQAKKTYDRAI 288
HC+LD++ +AI+RL +YPI IFI +S + + E + ++T+ +K+ ++ A
Sbjct: 1815 HCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQ 1874
Query: 289 KLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 330
KLEQE+ YFT ++QG L I Q ++ ++ +WIP+
Sbjct: 1875 KLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPA 1916
>gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens]
Length = 637
Score = 122 bits (305), Expect = 6e-28
Identities = 69/216 (31%), Positives = 117/216 (54%), Gaps = 19/216 (8%)
Query: 133 YEPVTRQEINYT---RPVIILGPMKDRIND---DLISEFPDKFGSCVPHTTRPKRDYEVD 186
YE V R + + R ++++GP +N+ LI P F S VPHTTR K+ YE++
Sbjct: 413 YEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMN 472
Query: 187 GRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIK 246
GR+YH+V S+E E I H+ +E G+Y +LYGTSV +V+ V GK C++D+ I+
Sbjct: 473 GREYHYV-SKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQ 531
Query: 247 RLQVAQLYPIAIFIKPRSLEPLMEMNK------------RLTEEQAKKTYDRAIKLEQEF 294
++ +L P IFIKP ++ + + K + +E ++ + A ++E +F
Sbjct: 532 GVRTHELKPYVIFIKPSNMRCMKQSRKNAKVITDYYVDMKFKDEDLQEMENLAQRMETQF 591
Query: 295 GEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 330
G++F ++ D+L D Q I++ W+P+
Sbjct: 592 GQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPA 627
Score = 57.0 bits (136), Expect = 2e-08
Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 4/76 (5%)
Query: 16 NQKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSE 73
N ++ +YVRAM +Y +D +P GL F+ GDIL +++ +D WWQAR++ +
Sbjct: 240 NSQQMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIVDQNDALWWQARKI--SDPAT 297
Query: 74 EMGVIPSKRRVERKER 89
G++PS ++RK+R
Sbjct: 298 CAGLVPSNHLLKRKQR 313
>gi|10092691 tight junction protein 3 [Homo sapiens]
Length = 952
Score = 100 bits (250), Expect = 1e-21
Identities = 90/336 (26%), Positives = 138/336 (41%), Gaps = 71/336 (21%)
Query: 20 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINA---------SDDEWWQARRVMLEG 70
S Y+R F+ + S P GL F GD+ HV++ + W A R+ +
Sbjct: 510 SFYIRTHFELEPS-----PPSGLGFTRGDVFHVLDTLHPGPGQSHARGGHWLAVRMGRDL 564
Query: 71 DSEEMGVIPSKRRVERKERARLKTVKFNAKPGVI---DSKGDIPGLGDDGYGTK--TLRG 125
+E G+IP++ R E+ PG +++ + L G K T R
Sbjct: 565 REQERGIIPNQSRAEQLASLEAAQRAVGVGPGSSAGSNARAEFWRLRGLRRGAKKTTQRS 624
Query: 126 QEDLIL--------SYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKF--GSCVPH 175
+EDL YE V +E ++ RPV+ILGP+ D L +E PD+F V
Sbjct: 625 REDLSALTRQGRYPPYERVVLREASFKRPVVILGPVADIAMQKLTAEMPDQFEIAETVSR 684
Query: 176 TTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKH 235
T P + ++D +VR +AE+ KH
Sbjct: 685 TDSPSKIIKLD--------------------------------------TVRVIAEKDKH 706
Query: 236 CILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRL---TEEQAKKTYDRAIKLEQ 292
+LDV+ +AI+RL Q YPI +F P S L + + L + ++ Y +A KL +
Sbjct: 707 ALLDVTPSAIERLNYVQYYPIVVFFIPESRPALKALRQWLAPASRRSTRRLYAQAQKLRK 766
Query: 293 EFGEYFTAIVQ-GDTLEDIYNQCKLVIEEQSGPFIW 327
FTA + T + Y + K +I EQ IW
Sbjct: 767 HSSHLFTATIPLNGTSDTWYQELKAIIREQQTRPIW 802
>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
Length = 1668
Score = 98.2 bits (243), Expect = 9e-21
Identities = 84/325 (25%), Positives = 135/325 (41%), Gaps = 58/325 (17%)
Query: 20 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW---WQARRVMLEGDSEEMG 76
S Y+R F+Y+K GLSF G++ V++ + W A R+ E G
Sbjct: 518 SFYIRTHFEYEKESP-----YGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERG 572
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLR-GQEDLIL---- 131
+IP+K R E+ L +V++ + D + LR +EDL
Sbjct: 573 IIPNKNRAEQ-----LASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQ 627
Query: 132 ----SYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 187
+YE V +E + RPV I GP+ D + L E PD + RD D
Sbjct: 628 TKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKSEP----RDAGTDQ 683
Query: 188 RDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKR 247
R + + +++ + ++ KH +LDV+ NA+ R
Sbjct: 684 RSSGII----------------------------RLHTIKQIIDQDKHALLDVTPNAVDR 715
Query: 248 LQVAQLYPIAIFIKPRSLEPLMEMNKRLTEE---QAKKTYDRAIKLEQEFGEYFTAIVQG 304
L AQ YPI +F+ P S + + M RL E A+K Y+R+ KL + FT +
Sbjct: 716 LNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINL 775
Query: 305 DTLED-IYNQCKLVIEEQSGPFIWI 328
+++ D Y K I++Q +W+
Sbjct: 776 NSMNDGWYGALKEAIQQQQNQLVWV 800
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 98.2 bits (243), Expect = 9e-21
Identities = 84/325 (25%), Positives = 135/325 (41%), Gaps = 58/325 (17%)
Query: 20 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW---WQARRVMLEGDSEEMG 76
S Y+R F+Y+K GLSF G++ V++ + W A R+ E G
Sbjct: 518 SFYIRTHFEYEKESP-----YGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERG 572
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLR-GQEDLIL---- 131
+IP+K R E+ L +V++ + D + LR +EDL
Sbjct: 573 IIPNKNRAEQ-----LASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQ 627
Query: 132 ----SYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 187
+YE V +E + RPV I GP+ D + L E PD + RD D
Sbjct: 628 TKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKSEP----RDAGTDQ 683
Query: 188 RDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKR 247
R + + +++ + ++ KH +LDV+ NA+ R
Sbjct: 684 RSSGII----------------------------RLHTIKQIIDQDKHALLDVTPNAVDR 715
Query: 248 LQVAQLYPIAIFIKPRSLEPLMEMNKRLTEE---QAKKTYDRAIKLEQEFGEYFTAIVQG 304
L AQ YPI +F+ P S + + M RL E A+K Y+R+ KL + FT +
Sbjct: 716 LNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINL 775
Query: 305 DTLED-IYNQCKLVIEEQSGPFIWI 328
+++ D Y K I++Q +W+
Sbjct: 776 NSMNDGWYGALKEAIQQQQNQLVWV 800
>gi|226874833 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 95.1 bits (235), Expect = 8e-20
Identities = 60/185 (32%), Positives = 97/185 (52%), Gaps = 9/185 (4%)
Query: 145 RPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEK 201
RPV++ GP K + L+ E FG V HTTR R E +G+DY+FV +RE M++
Sbjct: 5 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFV-TREVMQR 63
Query: 202 DIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIK 261
DI FIE +++ NLYGTS +V+ V + C+LDV ++ ++ L PI I ++
Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 123
Query: 262 PRSLEPLMEMNKRLTEEQAKKTYDR--AIKLEQEFGE---YFTAIVQGDTLEDIYNQCKL 316
P SL L + ++ E + R A + + E + F ++ D+L+ Y + K
Sbjct: 124 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAELKE 183
Query: 317 VIEEQ 321
+ E+
Sbjct: 184 ALSEE 188
>gi|226874831 guanylate kinase 1 isoform a [Homo sapiens]
Length = 218
Score = 95.1 bits (235), Expect = 8e-20
Identities = 60/185 (32%), Positives = 97/185 (52%), Gaps = 9/185 (4%)
Query: 145 RPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEK 201
RPV++ GP K + L+ E FG V HTTR R E +G+DY+FV +RE M++
Sbjct: 26 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFV-TREVMQR 84
Query: 202 DIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIK 261
DI FIE +++ NLYGTS +V+ V + C+LDV ++ ++ L PI I ++
Sbjct: 85 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 144
Query: 262 PRSLEPLMEMNKRLTEEQAKKTYDR--AIKLEQEFGE---YFTAIVQGDTLEDIYNQCKL 316
P SL L + ++ E + R A + + E + F ++ D+L+ Y + K
Sbjct: 145 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAELKE 204
Query: 317 VIEEQ 321
+ E+
Sbjct: 205 ALSEE 209
>gi|4504221 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 95.1 bits (235), Expect = 8e-20
Identities = 60/185 (32%), Positives = 97/185 (52%), Gaps = 9/185 (4%)
Query: 145 RPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEK 201
RPV++ GP K + L+ E FG V HTTR R E +G+DY+FV +RE M++
Sbjct: 5 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFV-TREVMQR 63
Query: 202 DIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIK 261
DI FIE +++ NLYGTS +V+ V + C+LDV ++ ++ L PI I ++
Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 123
Query: 262 PRSLEPLMEMNKRLTEEQAKKTYDR--AIKLEQEFGE---YFTAIVQGDTLEDIYNQCKL 316
P SL L + ++ E + R A + + E + F ++ D+L+ Y + K
Sbjct: 124 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAELKE 183
Query: 317 VIEEQ 321
+ E+
Sbjct: 184 ALSEE 188
>gi|42518065 tight junction protein 2 (zona occludens 2) isoform 2
[Homo sapiens]
Length = 1043
Score = 91.3 bits (225), Expect = 1e-18
Identities = 84/327 (25%), Positives = 140/327 (42%), Gaps = 65/327 (19%)
Query: 20 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW---WQARRVMLEGDSEEMG 76
S ++R+ F+ +K Q L+F G++ V++ D W A R+ G+ E G
Sbjct: 606 SFFIRSHFECEKETP-----QSLAFTRGEVFRVVDTLYDGKLGNWLAVRI---GNELEKG 657
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKT--LRGQEDLIL--- 131
+IP+K R E+ + NA+ + D + G K + +EDL
Sbjct: 658 LIPNKSRAEQMASVQ------NAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVVS 711
Query: 132 ------SYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEV 185
+YE V +E + RPV++ GP+ D + L +E PD F + T PK
Sbjct: 712 VSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTA---KTEPK----- 763
Query: 186 DGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAI 245
D K + N +VR + E+ KH +LDV+ A+
Sbjct: 764 ----------------DAGSEKSTGVVRLN---------TVRQIIEQDKHALLDVTPKAV 798
Query: 246 KRLQVAQLYPIAIFIKPRSLEPLMEMNKRL---TEEQAKKTYDRAIKLEQEFGEYFTAIV 302
L Q +PI IF P S + + M +RL + + ++K +D+A KL++ FTA +
Sbjct: 799 DLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTATI 858
Query: 303 QGDTLEDI-YNQCKLVIEEQSGPFIWI 328
++ D + K I+ Q G +W+
Sbjct: 859 NLNSANDSWFGSLKDTIQHQQGEAVWV 885
>gi|42518070 tight junction protein 2 (zona occludens 2) isoform 1
[Homo sapiens]
Length = 1190
Score = 91.3 bits (225), Expect = 1e-18
Identities = 84/327 (25%), Positives = 140/327 (42%), Gaps = 65/327 (19%)
Query: 20 SLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEW---WQARRVMLEGDSEEMG 76
S ++R+ F+ +K Q L+F G++ V++ D W A R+ G+ E G
Sbjct: 606 SFFIRSHFECEKETP-----QSLAFTRGEVFRVVDTLYDGKLGNWLAVRI---GNELEKG 657
Query: 77 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKT--LRGQEDLIL--- 131
+IP+K R E+ + NA+ + D + G K + +EDL
Sbjct: 658 LIPNKSRAEQMASVQ------NAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVVS 711
Query: 132 ------SYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEV 185
+YE V +E + RPV++ GP+ D + L +E PD F + T PK
Sbjct: 712 VSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTA---KTEPK----- 763
Query: 186 DGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAI 245
D K + N +VR + E+ KH +LDV+ A+
Sbjct: 764 ----------------DAGSEKSTGVVRLN---------TVRQIIEQDKHALLDVTPKAV 798
Query: 246 KRLQVAQLYPIAIFIKPRSLEPLMEMNKRL---TEEQAKKTYDRAIKLEQEFGEYFTAIV 302
L Q +PI IF P S + + M +RL + + ++K +D+A KL++ FTA +
Sbjct: 799 DLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTATI 858
Query: 303 QGDTLEDI-YNQCKLVIEEQSGPFIWI 328
++ D + K I+ Q G +W+
Sbjct: 859 NLNSANDSWFGSLKDTIQHQQGEAVWV 885
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 62.4 bits (150), Expect = 5e-10
Identities = 45/162 (27%), Positives = 73/162 (45%), Gaps = 9/162 (5%)
Query: 168 KFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVR 227
++G+C HTTRP E D DYHF IS++ ++ + KFI Y ++ YG + +V
Sbjct: 443 RYGAC--HTTRPPYFGEGDRVDYHF-ISQDVFDEMVNMGKFILTFSYGNHKYGLNRDTVE 499
Query: 228 FVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPL------MEMNKRLTEEQAK 281
+A G + + ++ L+ + P I + P + E + R E A
Sbjct: 500 GIARDGLASCIHMEIEGVRSLKYSYFEPRYILVVPMNKEKYEGYLRRKGLFSRAEIEFAV 559
Query: 282 KTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSG 323
D IK+ Q F YF ++ D L+ Y + +I E G
Sbjct: 560 SRVDLYIKINQNFPGYFDEVINADDLDVAYQKLSQLIREYLG 601
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,405,621
Number of Sequences: 37866
Number of extensions: 548490
Number of successful extensions: 1584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 1375
Number of HSP's gapped (non-prelim): 198
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.