Search of human proteins with 21040355

Search of human proteins with 21040355

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
         (168 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s...   342   9e-95
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa...   295   1e-80
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa...   295   1e-80
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa...   295   1e-80
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap...   295   1e-80
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa...   271   1e-73
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa...   268   1e-72
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa...   268   1e-72
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi...   119   9e-28
gi|17986001 major histocompatibility complex, class I, B precurs...   118   3e-27
gi|52630342 major histocompatibility complex, class I, C precurs...   117   5e-27
gi|149158702 major histocompatibility complex, class I, F isofor...   116   8e-27
gi|149158698 major histocompatibility complex, class I, F isofor...   116   8e-27
gi|62912479 major histocompatibility complex, class I, E precurs...   110   4e-25
gi|24797067 major histocompatibility complex, class I, A precurs...   108   3e-24
gi|4504415 major histocompatibility complex, class I, G precurso...   102   2e-22
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s...    99   2e-21
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi...    87   5e-18
gi|4504417 major histocompatibility complex, class I-related [Ho...    86   2e-17
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa...    83   1e-16
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]                 79   2e-15
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...    67   6e-12
gi|239740855 PREDICTED: similar to major histocompatibility comp...    67   6e-12
gi|239740853 PREDICTED: similar to major histocompatibility comp...    67   6e-12
gi|18641375 major histocompatibility complex, class II, DR beta ...    67   7e-12
gi|52630344 major histocompatibility complex, class II, DR beta ...    67   9e-12
gi|239758090 PREDICTED: major histocompatibility complex, class ...    67   9e-12
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...    67   9e-12
gi|239740745 PREDICTED: similar to HLA class II histocompatibili...    67   9e-12
gi|239740743 PREDICTED: similar to HLA class II histocompatibili...    67   9e-12

>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
           sapiens]
          Length = 168

 Score =  342 bits (877), Expect = 9e-95
 Identities = 168/168 (100%), Positives = 168/168 (100%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 60
           MGPRARPALLLLMLLQTAVLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 60

Query: 61  KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 120
           KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 61  KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 120

Query: 121 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 168
           PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 121 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 168


>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
           sapiens]
          Length = 325

 Score =  295 bits (756), Expect = 1e-80
 Identities = 142/143 (99%), Positives = 143/143 (100%)

Query: 26  LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           +PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 183 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 242

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
           GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 243 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 302

Query: 146 FIILRKRQGSRGAMGHYVLAERE 168
           FIILRKRQGSRGAMGHYVLAERE
Sbjct: 303 FIILRKRQGSRGAMGHYVLAERE 325



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
           sapiens]
          Length = 260

 Score =  295 bits (756), Expect = 1e-80
 Identities = 142/143 (99%), Positives = 143/143 (100%)

Query: 26  LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           +PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 118 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 177

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
           GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 178 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 237

Query: 146 FIILRKRQGSRGAMGHYVLAERE 168
           FIILRKRQGSRGAMGHYVLAERE
Sbjct: 238 FIILRKRQGSRGAMGHYVLAERE 260



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
           sapiens]
          Length = 256

 Score =  295 bits (756), Expect = 1e-80
 Identities = 142/143 (99%), Positives = 143/143 (100%)

Query: 26  LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           +PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 114 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
           GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 233

Query: 146 FIILRKRQGSRGAMGHYVLAERE 168
           FIILRKRQGSRGAMGHYVLAERE
Sbjct: 234 FIILRKRQGSRGAMGHYVLAERE 256



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
           sapiens]
          Length = 348

 Score =  295 bits (756), Expect = 1e-80
 Identities = 142/143 (99%), Positives = 143/143 (100%)

Query: 26  LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           +PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 206 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 265

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
           GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 266 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 325

Query: 146 FIILRKRQGSRGAMGHYVLAERE 168
           FIILRKRQGSRGAMGHYVLAERE
Sbjct: 326 FIILRKRQGSRGAMGHYVLAERE 348



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
           sapiens]
          Length = 242

 Score =  271 bits (694), Expect = 1e-73
 Identities = 131/135 (97%), Positives = 132/135 (97%)

Query: 34  HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 93
           +H  S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP
Sbjct: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167

Query: 94  PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 153
           PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ
Sbjct: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227

Query: 154 GSRGAMGHYVLAERE 168
           GSRGAMGHYVLAERE
Sbjct: 228 GSRGAMGHYVLAERE 242



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
           sapiens]
          Length = 246

 Score =  268 bits (686), Expect = 1e-72
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 40  VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 99
           VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR
Sbjct: 118 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 177

Query: 100 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 159
           YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM
Sbjct: 178 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 237

Query: 160 GHYVLAERE 168
           GHYVLAERE
Sbjct: 238 GHYVLAERE 246



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
           sapiens]
          Length = 334

 Score =  268 bits (686), Expect = 1e-72
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 40  VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 99
           VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR
Sbjct: 206 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 265

Query: 100 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 159
           YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM
Sbjct: 266 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 325

Query: 160 GHYVLAERE 168
           GHYVLAERE
Sbjct: 326 GHYVLAERE 334



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
           sapiens]
          Length = 366

 Score =  119 bits (299), Expect = 9e-28
 Identities = 58/135 (42%), Positives = 84/135 (62%), Gaps = 3/135 (2%)

Query: 27  PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PP   VTHH ++    TLRC AL +YP+ I++ W ++ +    ++ E  +  P+GDGT+Q
Sbjct: 221 PPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQ 279

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
            W  L VP GEEQRYTC+V+H GL +PL + WEP  +  L++G+I G+ + VV L  G +
Sbjct: 280 KWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV 339

Query: 146 FIILRKRQGSRGAMG 160
            I  +KR G  G  G
Sbjct: 340 -IWRKKRSGREGREG 353


>gi|17986001 major histocompatibility complex, class I, B precursor
           [Homo sapiens]
          Length = 362

 Score =  118 bits (295), Expect = 3e-27
 Identities = 56/138 (40%), Positives = 85/138 (61%), Gaps = 3/138 (2%)

Query: 27  PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PP   VTHH ++    TLRC AL +YP  IT+ W +D +    ++ E  +  P GD T+Q
Sbjct: 208 PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQ 266

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
            W  + VP GEEQRYTC V+H GL +PL + WEPS   T+ ++G+++G+AV  V++   +
Sbjct: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAV 326

Query: 145 LFIILRKRQGSRGAMGHY 162
           +  ++ +R+ S G  G Y
Sbjct: 327 VAAVMCRRKSSGGKGGSY 344


>gi|52630342 major histocompatibility complex, class I, C precursor
           [Homo sapiens]
          Length = 366

 Score =  117 bits (293), Expect = 5e-27
 Identities = 57/136 (41%), Positives = 83/136 (61%), Gaps = 3/136 (2%)

Query: 27  PPLVKVTHHVTSS-VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PP   VTHH  S    TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q
Sbjct: 208 PPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQ 266

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
            W  + VP G+EQRYTC ++H GL +PL + WEPS   T+ ++G+++G+AV VV+  +G 
Sbjct: 267 KWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGA 326

Query: 145 LFIILRKRQGSRGAMG 160
           +   +  R+ S G  G
Sbjct: 327 VVTAMMCRRKSSGGKG 342


>gi|149158702 major histocompatibility complex, class I, F isoform 1
           precursor [Homo sapiens]
          Length = 442

 Score =  116 bits (291), Expect = 8e-27
 Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)

Query: 27  PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PP   V HH ++    TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q
Sbjct: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
            W  + VPPGEEQRYTC V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   +
Sbjct: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323

Query: 145 LFIILRKRQGSRGAMGHY 162
           +  ++ +++ S    G Y
Sbjct: 324 VAAVMWRKKSSDRNRGSY 341


>gi|149158698 major histocompatibility complex, class I, F isoform 2
           precursor [Homo sapiens]
          Length = 346

 Score =  116 bits (291), Expect = 8e-27
 Identities = 55/138 (39%), Positives = 84/138 (60%), Gaps = 3/138 (2%)

Query: 27  PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PP   V HH ++    TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q
Sbjct: 205 PPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQ 263

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
            W  + VPPGEEQRYTC V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   +
Sbjct: 264 KWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAV 323

Query: 145 LFIILRKRQGSRGAMGHY 162
           +  ++ +++ S    G Y
Sbjct: 324 VAAVMWRKKSSDRNRGSY 341


>gi|62912479 major histocompatibility complex, class I, E precursor
           [Homo sapiens]
          Length = 358

 Score =  110 bits (276), Expect = 4e-25
 Identities = 54/144 (37%), Positives = 87/144 (60%), Gaps = 3/144 (2%)

Query: 25  LLPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 83
           L PP   VTHH ++    TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT
Sbjct: 203 LEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGT 261

Query: 84  YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFI 142
           +Q W  + VP GEEQRYTC V+H GL +P+ + W+P+   T+ ++G+I+G+ +   ++  
Sbjct: 262 FQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSG 321

Query: 143 GILFIILRKRQGSRGAMGHYVLAE 166
            ++  ++ +++ S G  G Y  AE
Sbjct: 322 AVVAAVIWRKKSSGGKGGSYSKAE 345


>gi|24797067 major histocompatibility complex, class I, A precursor
           [Homo sapiens]
          Length = 365

 Score =  108 bits (269), Expect = 3e-24
 Identities = 53/141 (37%), Positives = 83/141 (58%), Gaps = 3/141 (2%)

Query: 27  PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PP   +THH ++    TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q
Sbjct: 208 PPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQ 266

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
            W  + VP GEEQRYTC V+H GL +PL + WE S   T+ ++G+I+G+ +   ++   +
Sbjct: 267 KWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAV 326

Query: 145 LFIILRKRQGSRGAMGHYVLA 165
           +  ++ +R+ S    G Y  A
Sbjct: 327 VAAVMWRRKSSDRKGGSYTQA 347


>gi|4504415 major histocompatibility complex, class I, G precursor
           [Homo sapiens]
          Length = 338

 Score =  102 bits (254), Expect = 2e-22
 Identities = 50/131 (38%), Positives = 78/131 (59%), Gaps = 3/131 (2%)

Query: 27  PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PP   VTHH V     TLRC AL +YP  I + W +D +    ++ E  +  P GDGT+Q
Sbjct: 208 PPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQ 266

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 144
            W  + VP GEEQRYTC V+H GL +PL++ W+ S   T+ ++G+++G+ V   ++    
Sbjct: 267 KWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAA 326

Query: 145 LFIILRKRQGS 155
           +  +L +++ S
Sbjct: 327 VAAVLWRKKSS 337


>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
           sapiens]
          Length = 76

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 50/51 (98%), Positives = 51/51 (100%)

Query: 118 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 168
           +PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26  QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76



 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 26/27 (96%), Positives = 26/27 (96%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLLLP 27
          MGPRARPALLLLMLLQTAVLQGRLL P
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLLQP 27


>gi|4557751 MHC class I polypeptide-related sequence A [Homo
           sapiens]
          Length = 383

 Score = 87.4 bits (215), Expect = 5e-18
 Identities = 48/130 (36%), Positives = 68/130 (52%), Gaps = 16/130 (12%)

Query: 23  RLLLPPLVKVTHHVTSSVT-TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 81
           R  +PP+V VT    S    T+ CRA  +YP NIT+ W +D   +     +  DVLP+G+
Sbjct: 202 RRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGN 261

Query: 82  GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG----------TLVIGVIS 131
           GTYQ W+   +  GEEQR+TC +EH G          P PSG          T  +  ++
Sbjct: 262 GTYQTWVATRICQGEEQRFTCYMEHSGNHST-----HPVPSGKVLVLQSHWQTFHVSAVA 316

Query: 132 GIAVFVVILF 141
             A+FV+I+F
Sbjct: 317 AAAIFVIIIF 326


>gi|4504417 major histocompatibility complex, class I-related [Homo
           sapiens]
          Length = 341

 Score = 85.5 bits (210), Expect = 2e-17
 Identities = 49/127 (38%), Positives = 74/127 (58%), Gaps = 4/127 (3%)

Query: 27  PPLVKVTHHVT-SSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
           PPLV+V    T   VT L C+A  +YP  I M W+K+ + +  +E +  D+LP+GDGTYQ
Sbjct: 203 PPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQ 261

Query: 86  GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
            W ++ + P     Y+C VEH G+   L V  E S +  LV+  +SG  V V++L  G+ 
Sbjct: 262 AWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVG 319

Query: 146 FIILRKR 152
            ++ R+R
Sbjct: 320 VLVWRRR 326


>gi|167857788 MHC class I polypeptide-related sequence B [Homo
           sapiens]
          Length = 383

 Score = 82.8 bits (203), Expect = 1e-16
 Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 6/106 (5%)

Query: 23  RLLLPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 81
           R  +PP+V VT   V+    T+ CRA ++YP+NIT+ W +D   +     +  DVLP+G+
Sbjct: 202 RRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGN 261

Query: 82  GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 127
           GTYQ W+   +  GEEQR+TC +EH G          P PSG  ++
Sbjct: 262 GTYQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302


>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
          Length = 298

 Score = 79.0 bits (193), Expect = 2e-15
 Identities = 43/117 (36%), Positives = 61/117 (52%), Gaps = 8/117 (6%)

Query: 7   PALLLLMLLQTAVLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPM 66
           PA L   L  +  +  R   P +V  +H        L+C A ++YP  I + W +  +  
Sbjct: 187 PATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQ 246

Query: 67  DAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 120
                EP+   DVL NG+GTYQ W+ +AVPP +   Y+C V+H  L QPL+V WE S
Sbjct: 247 -----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS 298


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score = 67.4 bits (163), Expect = 6e-12
 Identities = 51/152 (33%), Positives = 76/152 (50%), Gaps = 7/152 (4%)

Query: 11  LLMLLQTAVLQGRLLLPPLVKVTHHVTSSV---TTLRCRALNYYPQNITMKWLKDKQPMD 67
           LL L  +  L   LL+ P V V    T  +     L C    +YP +I ++W ++ Q   
Sbjct: 96  LLCLPDSFPLPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK 155

Query: 68  AKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 127
           A       ++ NGD T+Q  + L   P   + YTCQVEHP +  PL V W  + S +   
Sbjct: 156 AGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQS 213

Query: 128 GVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
            ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 214 KMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 245


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 67.4 bits (163), Expect = 6e-12
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 145 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 203

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 204 QVEHPSVTSPLTVEWS-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 259


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score = 67.4 bits (163), Expect = 6e-12
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 144 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 202

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 203 QVEHPSVTSPLTVEWS-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 258


>gi|18641375 major histocompatibility complex, class II, DR beta 5
           precursor [Homo sapiens]
          Length = 266

 Score = 67.0 bits (162), Expect = 7e-12
 Identities = 40/117 (34%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 144 LVCSVNGFYPGSIEVRWFRNSQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 202

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  + ++G  G
Sbjct: 203 QVEHPSVTSPLTVEWR-AQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQKGHSG 258


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 144 LVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 202

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 203 QVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSG 258


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 156 LVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 214

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 215 QVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSG 270


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 144 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 202

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 203 QVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 258


>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 144 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 202

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 203 QVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 258


>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
           L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L   P   + YTC
Sbjct: 142 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLETVPRSGEVYTC 200

Query: 103 QVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIILRKRQGSRG 157
           QVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  R ++G  G
Sbjct: 201 QVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 256


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.142    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,280,084
Number of Sequences: 37866
Number of extensions: 348080
Number of successful extensions: 1071
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 900
Number of HSP's gapped (non-prelim): 164
length of query: 168
length of database: 18,247,518
effective HSP length: 95
effective length of query: 73
effective length of database: 14,650,248
effective search space: 1069468104
effective search space used: 1069468104
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.